Class E vacuolar protein-sorting machinery protein HSE1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008280 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Human
Match: GRAP (GRB2 related adaptor protein [Source:HGNC Symbol;Acc:HGNC:4562]) HSP 1 Score: 179.874 bits (455), Expect = 2.546e-55 Identity = 90/227 (39.65%), Postives = 139/227 (61.23%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
ME++AL+ F T+SD+L FNK + I++ME D NWY+AE + G +P NYIR+ P+PWY SRQ AEEIL++ GAF++R SE FS+SV ++ HFK+L++ G Y++W +KF S+N+L++F+ +I ++ + L+D +P ++ P + A +D+ A P +LSF+RGD+I V + D +W RGR + G FP +YVQ
Sbjct: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPWYSGRISRQLAEEILMKRNHL-------GAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEP-----LLKSPGACFAQ--AQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQ 213
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Human
Match: GRB2 (growth factor receptor bound protein 2 [Source:HGNC Symbol;Acc:HGNC:4566]) HSP 1 Score: 169.859 bits (429), Expect = 1.864e-51 Identity = 86/226 (38.05%), Postives = 129/226 (57.08%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D++ + +QP V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE-----QVPQQPTY----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 55.4546 bits (132), Expect = 1.881e-8 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRGD++ V +E D NW + L K+G P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Human
Match: GRB2 (growth factor receptor bound protein 2 [Source:HGNC Symbol;Acc:HGNC:4566]) HSP 1 Score: 169.859 bits (429), Expect = 1.864e-51 Identity = 86/226 (38.05%), Postives = 129/226 (57.08%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D++ + +QP V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE-----QVPQQPTY----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 55.4546 bits (132), Expect = 1.881e-8 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRGD++ V +E D NW + L K+G P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Human
Match: GRB2 (growth factor receptor bound protein 2 [Source:HGNC Symbol;Acc:HGNC:4566]) HSP 1 Score: 169.859 bits (429), Expect = 1.864e-51 Identity = 86/226 (38.05%), Postives = 129/226 (57.08%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D++ + +QP V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE-----QVPQQPTY----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 55.4546 bits (132), Expect = 1.881e-8 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRGD++ V +E D NW + L K+G P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Human
Match: GRB2 (growth factor receptor bound protein 2 [Source:HGNC Symbol;Acc:HGNC:4566]) HSP 1 Score: 169.859 bits (429), Expect = 1.864e-51 Identity = 86/226 (38.05%), Postives = 129/226 (57.08%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D++ + +QP V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE-----QVPQQPTY----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 55.4546 bits (132), Expect = 1.881e-8 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRGD++ V +E D NW + L K+G P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Celegans
Match: sem-5 (Sex muscle abnormal protein 5 [Source:UniProtKB/Swiss-Prot;Acc:P29355]) HSP 1 Score: 170.629 bits (431), Expect = 4.691e-52 Identity = 87/226 (38.50%), Postives = 130/226 (57.52%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEA+A HDF D+L F + + +++ + DP+WY+AE G +P NYIR+ WYL +R AE +L + TV DG F++R+ E FS+SV+ + HFK+L+D+ G YY+WA KF S+N+L+ +H S+ ++LL DM VE+ + V A +D+ EL+FKRGDVI + K+D NW G+L ++ G+FP NYV
Sbjct: 1 MEAVAEHDFQAGSPDELSFKRGNTLKVLNKDEDPHWYKAELDGNEGFIPSNYIRMTECNWYLGKITRNDAEVLLKKPTV------RDGHFLVRQCESSPGEFSISVRFQDSVQHFKVLRDQNGKYYLWAVKFNSLNELVAYHRTASVSRTHTILLSDMN----VET--------KFVQALFDFNPQESGELAFKRGDVITLINKDDPNWWEGQLNNRRGIFPSNYV 208 HSP 2 Score: 57.3806 bits (137), Expect = 1.563e-9 Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGK-EDANWLRGRLRDKEGVFPFNYVQ*ITC 732
+A +D+QA SPDELSFKRG+ + V K ED +W + L EG P NY++ C
Sbjct: 3 AVAEHDFQAGSPDELSFKRGNTLKVLNKDEDPHWYKAELDGNEGFIPSNYIRMTEC 58
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Celegans
Match: itsn-1 (ITSN (Intersectin) family [Source:UniProtKB/TrEMBL;Acc:E6N0W1]) HSP 1 Score: 69.3218 bits (168), Expect = 5.744e-13 Identity = 36/71 (50.70%), Postives = 44/71 (61.97%), Query Frame = 1
Query: 517 PSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRG-RLRD--KEGVFPFNYVQ 720
P V+ + + A R A YDY+AS PDEL FK GDVI+VT K +A W G R +D K G+FP NYVQ
Sbjct: 560 PGEYVKVLEEAASPATRATAVYDYEASQPDELGFKTGDVIIVTDKSEAEWWSGHREQDPSKSGLFPSNYVQ 630 HSP 2 Score: 48.1358 bits (113), Expect = 5.162e-6 Identity = 28/80 (35.00%), Postives = 44/80 (55.00%), Query Frame = 1
Query: 517 PSRLVESIRQPAMN---ERRVIAAYDYQASSPDELSFKRGDVIVV--TGKEDANWLRGRLRDKEGVFPFNYVQ*ITCIPV 741
P+ ++ Q A N + A + ++A S DELSF+ GDVI+V + + W G+LR+K G FP +V+ I +P
Sbjct: 193 PAHSKGAVDQSAFNIHDTYKCRALFAFEARSEDELSFEPGDVIIVFQSHAAEPGWRAGQLREKVGWFPEAFVEAIAAVPT 272 HSP 3 Score: 47.7506 bits (112), Expect = 5.797e-6 Identity = 24/71 (33.80%), Postives = 38/71 (53.52%), Query Frame = 1
Query: 508 DMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
D+ PS + + A ++ YD++A +L+ GD I+V K D W +GR +EG+FP NYV+
Sbjct: 414 DVVPSDVTLQASETAPQQQLYTVIYDFEAVETTDLALHVGDTILVLEKND-EWWKGRCNGREGIFPANYVE 483
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Celegans
Match: itsn-1 (ITSN (Intersectin) family [Source:UniProtKB/TrEMBL;Acc:E6N0W1]) HSP 1 Score: 69.3218 bits (168), Expect = 5.968e-13 Identity = 36/71 (50.70%), Postives = 44/71 (61.97%), Query Frame = 1
Query: 517 PSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRG-RLRD--KEGVFPFNYVQ 720
P V+ + + A R A YDY+AS PDEL FK GDVI+VT K +A W G R +D K G+FP NYVQ
Sbjct: 562 PGEYVKVLEEAASPATRATAVYDYEASQPDELGFKTGDVIIVTDKSEAEWWSGHREQDPSKSGLFPSNYVQ 632 HSP 2 Score: 48.1358 bits (113), Expect = 5.260e-6 Identity = 28/80 (35.00%), Postives = 44/80 (55.00%), Query Frame = 1
Query: 517 PSRLVESIRQPAMN---ERRVIAAYDYQASSPDELSFKRGDVIVV--TGKEDANWLRGRLRDKEGVFPFNYVQ*ITCIPV 741
P+ ++ Q A N + A + ++A S DELSF+ GDVI+V + + W G+LR+K G FP +V+ I +P
Sbjct: 195 PAHSKGAVDQSAFNIHDTYKCRALFAFEARSEDELSFEPGDVIIVFQSHAAEPGWRAGQLREKVGWFPEAFVEAIAAVPT 274 HSP 3 Score: 47.7506 bits (112), Expect = 5.907e-6 Identity = 24/71 (33.80%), Postives = 38/71 (53.52%), Query Frame = 1
Query: 508 DMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
D+ PS + + A ++ YD++A +L+ GD I+V K D W +GR +EG+FP NYV+
Sbjct: 416 DVVPSDVTLQASETAPQQQLYTVIYDFEAVETTDLALHVGDTILVLEKND-EWWKGRCNGREGIFPANYVE 485
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Celegans
Match: src-2 (Tyrosine protein-kinase src-2 [Source:UniProtKB/Swiss-Prot;Acc:O45539]) HSP 1 Score: 68.5514 bits (166), Expect = 8.036e-13 Identity = 45/148 (30.41%), Postives = 80/148 (54.05%), Query Frame = 1
Query: 49 IALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQ--KSGLVPFNYI----RLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQK-FGSINKLIEFHYK 471
+AL + DDL F K+ I+ I++ ++ +W+ A +K ++G +P NY+ + PWY R AE+ LL + + GAF++R SE SLSV+++ + H++I Q + G Y+I ++ F +++ LI HY+
Sbjct: 63 VALFQYDARTDDDLSFKKDDILEILN-DTQGDWWFARHKATGRTGYIPSNYVAREKSIESQPWYFGKMRRIDAEKCLLHT------LNEHGAFLVRDSESRQHDLSLSVRENDSVKHYRIRQLDHGGYFIARRRPFATLHDLIA-HYQ 202
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Celegans
Match: itsn-1 (ITSN (Intersectin) family [Source:UniProtKB/TrEMBL;Acc:E6N0W1]) HSP 1 Score: 68.9366 bits (167), Expect = 8.269e-13 Identity = 36/71 (50.70%), Postives = 44/71 (61.97%), Query Frame = 1
Query: 517 PSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRG-RLRD--KEGVFPFNYVQ 720
P V+ + + A R A YDY+AS PDEL FK GDVI+VT K +A W G R +D K G+FP NYVQ
Sbjct: 753 PGEYVKVLEEAASPATRATAVYDYEASQPDELGFKTGDVIIVTDKSEAEWWSGHREQDPSKSGLFPSNYVQ 823 HSP 2 Score: 47.7506 bits (112), Expect = 7.441e-6 Identity = 24/61 (39.34%), Postives = 37/61 (60.66%), Query Frame = 1
Query: 565 RVIAAYDYQASSPDELSFKRGDVIVV--TGKEDANWLRGRLRDKEGVFPFNYVQ*ITCIPV 741
+ A + ++A S DELSF+ GDVI+V + + W G+LR+K G FP +V+ I +P
Sbjct: 405 KCRALFAFEARSEDELSFEPGDVIIVFQSHAAEPGWRAGQLREKVGWFPEAFVEAIAAVPT 465
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Fly
Match: drk (gene:FBgn0004638 transcript:FBtr0087695) HSP 1 Score: 172.555 bits (436), Expect = 6.501e-53 Identity = 90/226 (39.82%), Postives = 128/226 (56.64%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA HDF T D+L F K I+ I++ME D NWYRAE K GL+P NYI + + WY +R AE++L + +GAF++R SE FSLSVK + HFK+L+D +++W KF S+N+L+E+H S+ + + L+DM P ++ V A YD+ EL F+RGDVI VT + D NW G + +++G+FP YV
Sbjct: 1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRITRADAEKLLSN--------KHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEML------------VQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYV 206 HSP 2 Score: 48.9062 bits (115), Expect = 1.345e-6 Identity = 20/52 (38.46%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVI-VVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
IA +D+ A++ DELSF++ ++ ++ ++D+NW R L KEG+ P NY++
Sbjct: 3 AIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Fly
Match: drk (gene:FBgn0004638 transcript:FBtr0087694) HSP 1 Score: 172.555 bits (436), Expect = 6.501e-53 Identity = 90/226 (39.82%), Postives = 128/226 (56.64%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA HDF T D+L F K I+ I++ME D NWYRAE K GL+P NYI + + WY +R AE++L + +GAF++R SE FSLSVK + HFK+L+D +++W KF S+N+L+E+H S+ + + L+DM P ++ V A YD+ EL F+RGDVI VT + D NW G + +++G+FP YV
Sbjct: 1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRITRADAEKLLSN--------KHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEML------------VQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYV 206 HSP 2 Score: 48.9062 bits (115), Expect = 1.345e-6 Identity = 20/52 (38.46%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVI-VVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
IA +D+ A++ DELSF++ ++ ++ ++D+NW R L KEG+ P NY++
Sbjct: 3 AIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Fly
Match: drk (gene:FBgn0004638 transcript:FBtr0087698) HSP 1 Score: 172.555 bits (436), Expect = 6.501e-53 Identity = 90/226 (39.82%), Postives = 128/226 (56.64%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA HDF T D+L F K I+ I++ME D NWYRAE K GL+P NYI + + WY +R AE++L + +GAF++R SE FSLSVK + HFK+L+D +++W KF S+N+L+E+H S+ + + L+DM P ++ V A YD+ EL F+RGDVI VT + D NW G + +++G+FP YV
Sbjct: 1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRITRADAEKLLSN--------KHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEML------------VQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYV 206 HSP 2 Score: 48.9062 bits (115), Expect = 1.345e-6 Identity = 20/52 (38.46%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVI-VVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
IA +D+ A++ DELSF++ ++ ++ ++D+NW R L KEG+ P NY++
Sbjct: 3 AIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Fly
Match: drk (gene:FBgn0004638 transcript:FBtr0087696) HSP 1 Score: 172.555 bits (436), Expect = 6.501e-53 Identity = 90/226 (39.82%), Postives = 128/226 (56.64%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA HDF T D+L F K I+ I++ME D NWYRAE K GL+P NYI + + WY +R AE++L + +GAF++R SE FSLSVK + HFK+L+D +++W KF S+N+L+E+H S+ + + L+DM P ++ V A YD+ EL F+RGDVI VT + D NW G + +++G+FP YV
Sbjct: 1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRITRADAEKLLSN--------KHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEML------------VQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYV 206 HSP 2 Score: 48.9062 bits (115), Expect = 1.345e-6 Identity = 20/52 (38.46%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVI-VVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
IA +D+ A++ DELSF++ ++ ++ ++D+NW R L KEG+ P NY++
Sbjct: 3 AIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Fly
Match: drk (gene:FBgn0004638 transcript:FBtr0087697) HSP 1 Score: 172.555 bits (436), Expect = 6.501e-53 Identity = 90/226 (39.82%), Postives = 128/226 (56.64%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA HDF T D+L F K I+ I++ME D NWYRAE K GL+P NYI + + WY +R AE++L + +GAF++R SE FSLSVK + HFK+L+D +++W KF S+N+L+E+H S+ + + L+DM P ++ V A YD+ EL F+RGDVI VT + D NW G + +++G+FP YV
Sbjct: 1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRITRADAEKLLSN--------KHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEML------------VQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYV 206 HSP 2 Score: 48.9062 bits (115), Expect = 1.345e-6 Identity = 20/52 (38.46%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVI-VVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
IA +D+ A++ DELSF++ ++ ++ ++D+NW R L KEG+ P NY++
Sbjct: 3 AIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Zebrafish
Match: grb2a (growth factor receptor-bound protein 2a [Source:ZFIN;Acc:ZDB-GENE-041121-1]) HSP 1 Score: 171.014 bits (432), Expect = 4.164e-52 Identity = 87/226 (38.50%), Postives = 125/226 (55.31%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N L+++H S+ + + L+D I Q N V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKEGFIPKNYIEMKPHPWFYGKIPRAKAEEMLNKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNSLVDYHRSTSVSRNQPIFLRD---------IEQVPQNSTYVQALFDFDPQEDGELGFRRGDFIQVLDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 55.0694 bits (131), Expect = 1.433e-8 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRG+++ V +E D NW + L KEG P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKEGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Zebrafish
Match: grb2a (growth factor receptor-bound protein 2a [Source:ZFIN;Acc:ZDB-GENE-041121-1]) HSP 1 Score: 171.014 bits (432), Expect = 4.164e-52 Identity = 87/226 (38.50%), Postives = 125/226 (55.31%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N L+++H S+ + + L+D I Q N V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKEGFIPKNYIEMKPHPWFYGKIPRAKAEEMLNKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNSLVDYHRSTSVSRNQPIFLRD---------IEQVPQNSTYVQALFDFDPQEDGELGFRRGDFIQVLDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 55.0694 bits (131), Expect = 1.433e-8 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRG+++ V +E D NW + L KEG P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKEGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Zebrafish
Match: grb2a (growth factor receptor-bound protein 2a [Source:ZFIN;Acc:ZDB-GENE-041121-1]) HSP 1 Score: 171.014 bits (432), Expect = 4.164e-52 Identity = 87/226 (38.50%), Postives = 125/226 (55.31%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N L+++H S+ + + L+D I Q N V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKEGFIPKNYIEMKPHPWFYGKIPRAKAEEMLNKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNSLVDYHRSTSVSRNQPIFLRD---------IEQVPQNSTYVQALFDFDPQEDGELGFRRGDFIQVLDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 55.0694 bits (131), Expect = 1.433e-8 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRG+++ V +E D NW + L KEG P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKEGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Zebrafish
Match: grb2a (growth factor receptor-bound protein 2a [Source:ZFIN;Acc:ZDB-GENE-041121-1]) HSP 1 Score: 171.014 bits (432), Expect = 4.164e-52 Identity = 87/226 (38.50%), Postives = 125/226 (55.31%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N L+++H S+ + + L+D I Q N V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKEGFIPKNYIEMKPHPWFYGKIPRAKAEEMLNKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNSLVDYHRSTSVSRNQPIFLRD---------IEQVPQNSTYVQALFDFDPQEDGELGFRRGDFIQVLDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 55.0694 bits (131), Expect = 1.433e-8 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRG+++ V +E D NW + L KEG P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKEGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Zebrafish
Match: grb2b (growth factor receptor-bound protein 2b [Source:ZFIN;Acc:ZDB-GENE-040426-1975]) HSP 1 Score: 169.088 bits (427), Expect = 2.721e-51 Identity = 87/226 (38.50%), Postives = 125/226 (55.31%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + +PW+ R RAEEIL + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D I Q + V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKAHPWFFGRIPRARAEEILNKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRTTSVSRNQQIFLRD---------IEQVPQHPTYVQALFDFDPQEDGELGFRRGDFIQVLDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 53.5286 bits (127), Expect = 4.554e-8 Identity = 24/52 (46.15%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRG+++ V +E D NW + L K+G P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Xenopus
Match: ndufs3 (NADH:ubiquinone oxidoreductase core subunit S3 [Source:Xenbase;Acc:XB-GENE-997488]) HSP 1 Score: 170.244 bits (430), Expect = 1.766e-51 Identity = 86/233 (36.91%), Postives = 130/233 (55.79%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKP-------SRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEA+A +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D++ R ++QP V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAVAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLGKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQVHGGDRATNLLQQPTY----VQALFDFDPQEDGELGFRRGDFIQVVDNSDPNWWKGTCLGQTGMFPRNYV 222 HSP 2 Score: 54.6842 bits (130), Expect = 3.046e-8 Identity = 24/52 (46.15%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
+A YD++A++ DELSFKRGD++ V +E D NW + L K+G P NY++
Sbjct: 3 AVAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Xenopus
Match: ndufs3 (NADH:ubiquinone oxidoreductase core subunit S3 [Source:Xenbase;Acc:XB-GENE-997488]) HSP 1 Score: 169.088 bits (427), Expect = 3.193e-51 Identity = 85/226 (37.61%), Postives = 129/226 (57.08%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEA+A +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D++ + +QP V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAVAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLGKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE-----QVPQQPTY----VQALFDFDPQEDGELGFRRGDFIQVVDNSDPNWWKGTCLGQTGMFPRNYV 210 HSP 2 Score: 54.6842 bits (130), Expect = 2.715e-8 Identity = 24/52 (46.15%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
+A YD++A++ DELSFKRGD++ V +E D NW + L K+G P NY++
Sbjct: 3 AVAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Xenopus
Match: ddx59 (Xenopus tropicalis GRB2 related adaptor protein (grap), mRNA. [Source:RefSeq mRNA;Acc:NM_001345939]) HSP 1 Score: 169.088 bits (427), Expect = 4.584e-51 Identity = 92/229 (40.17%), Postives = 130/229 (56.77%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEV--GNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
MEA A+++F T+ D+L F K II I++ME D NW++AE + G +P NYI++ P+PWY SRQ AEEILL+ GAF++R SE FS+SV + HFK+L+D G YY+W KF S+N+L++++ ++SI + L D + R + R V A YD+ P L F+RGD+I V D NW RGR+ G+FP NYV
Sbjct: 1 MEATAIYNFKTTERDELPFKKGDIIKILNMEDDQNWFKAELFGREGYIPKNYIKVKPHPWYAGRISRQVAEEILLKRNFV-------GAFLIRDSESSPGDFSISVNYGHHVQHFKVLRDTESNGKYYLWEAKFNSLNELVDYYRRHSIAKFHEVFLCDEEQKRKI----------RYVQARYDFTPDQPTGLFFRRGDIIEVLDCSDPNWWRGRISGVTGMFPQNYVH 212
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Xenopus
Match: GRAP2 (GRB2 related adaptor protein 2 [Source:NCBI gene;Acc:100492322]) HSP 1 Score: 163.31 bits (412), Expect = 5.996e-49 Identity = 92/227 (40.53%), Postives = 133/227 (58.59%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAA-YDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEA A+++F + D+L F K ++ I + SD NWY++E G VP NY+ + WY N SR AE IL+ G FV GAFI+R S+ FS+SV+ + ++ HFK+++D GNYY+W +KF S+NKL+E++ SI +K + L++ E+ P R++ A YD+QA PDEL F DVI V DA+W GRL ++ G+FP NYV
Sbjct: 1 MEAQAMYEFNASGEDELSFKKGDVLKI--LSSDDNWYKSELNGSEGYVPKNYVEVHFPRWYCENISRGEAESILI-----GRFV---GAFIIRASQTSKGEFSMSVRDEDDVQHFKVMRDIRGNYYLWTEKFKSLNKLVEYYKTASISRQKEIYLREEGS----EAQASPTPQRIRMVKALYDFQAMEPDELGFIYSDVIEVLDCSDASWWMGRLGERVGLFPSNYV 213 HSP 2 Score: 48.9062 bits (115), Expect = 2.739e-6 Identity = 23/49 (46.94%), Postives = 31/49 (63.27%), Query Frame = 1
Query: 574 AAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
A Y++ AS DELSFK+GDV+ + +D NW + L EG P NYV+
Sbjct: 5 AMYEFNASGEDELSFKKGDVLKILSSDD-NWYKSELNGSEGYVPKNYVE 52
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Xenopus
Match: GRAP2 (GRB2 related adaptor protein 2 [Source:NCBI gene;Acc:100492322]) HSP 1 Score: 160.614 bits (405), Expect = 5.913e-48 Identity = 91/226 (40.27%), Postives = 132/226 (58.41%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEA A+++F + D+L F K ++ I + SD NWY++E G VP NY+ + WY N SR AE IL+ G FV GAFI+R S+ FS+SV+ + ++ HFK+++D GNYY+W +KF S+NKL+E++ SI +K + L++ V++ Q A+ YD+QA PDEL F DVI V DA+W GRL ++ G+FP NYV
Sbjct: 1 MEAQAMYEFNASGEDELSFKKGDVLKI--LSSDDNWYKSELNGSEGYVPKNYVEVHFPRWYCENISRGEAESILI-----GRFV---GAFIIRASQTSKGEFSMSVRDEDDVQHFKVMRDIRGNYYLWTEKFKSLNKLVEYYKTASISRQKEIYLREE-----VQTTPQGAL--------YDFQAMEPDELGFIYSDVIEVLDCSDASWWMGRLGERVGLFPSNYV 203 HSP 2 Score: 48.9062 bits (115), Expect = 2.448e-6 Identity = 23/49 (46.94%), Postives = 31/49 (63.27%), Query Frame = 1
Query: 574 AAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
A Y++ AS DELSFK+GDV+ + +D NW + L EG P NYV+
Sbjct: 5 AMYEFNASGEDELSFKKGDVLKILSSDD-NWYKSELNGSEGYVPKNYVE 52
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Mouse
Match: Grap (GRB2-related adaptor protein [Source:MGI Symbol;Acc:MGI:1918770]) HSP 1 Score: 181.415 bits (459), Expect = 3.766e-56 Identity = 91/227 (40.09%), Postives = 137/227 (60.35%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
ME++AL+ F T+SD+L FNK + I++ME D NWY+AE + G VP NYIR+ P+PWY SRQ AEE L++ GAF++R SE FS+SV ++ HFK+L++ G Y++W +KF S+N+L++F+ +I R+ + L D +P L++ R A +D+ A P +LS +RGD++ V +ED +W RGR + G FP +YVQ
Sbjct: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGAEGFVPKNYIRVKPHPWYSGRISRQLAEETLMKRNHL-------GAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNELVDFYRTTTIAKRRQIFLCDEQP--LIKPSRACFAQ-----AQFDFSAQDPSQLSLRRGDIVEVVEREDPHWWRGRAGGRLGFFPRSYVQ 213
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Mouse
Match: Grb2 (growth factor receptor bound protein 2 [Source:MGI Symbol;Acc:MGI:95805]) HSP 1 Score: 170.244 bits (430), Expect = 1.149e-51 Identity = 86/226 (38.05%), Postives = 129/226 (57.08%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D++ + +QP V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE-----QMPQQPTY----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 55.4546 bits (132), Expect = 1.197e-8 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRGD++ V +E D NW + L K+G P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Mouse
Match: Grb2 (growth factor receptor bound protein 2 [Source:MGI Symbol;Acc:MGI:95805]) HSP 1 Score: 170.244 bits (430), Expect = 1.149e-51 Identity = 86/226 (38.05%), Postives = 129/226 (57.08%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D++ + +QP V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE-----QMPQQPTY----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 55.4546 bits (132), Expect = 1.197e-8 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRGD++ V +E D NW + L K+G P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Mouse
Match: Grb2 (growth factor receptor bound protein 2 [Source:MGI Symbol;Acc:MGI:95805]) HSP 1 Score: 158.688 bits (400), Expect = 1.840e-47 Identity = 83/226 (36.73%), Postives = 122/226 (53.98%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D +E + Q EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRD------IEQMPQ-----------------EDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 196 HSP 2 Score: 55.4546 bits (132), Expect = 9.295e-9 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRGD++ V +E D NW + L K+G P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Mouse
Match: Grb2 (growth factor receptor bound protein 2 [Source:MGI Symbol;Acc:MGI:95805]) HSP 1 Score: 117.472 bits (293), Expect = 8.614e-32 Identity = 67/226 (29.65%), Postives = 104/226 (46.02%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + I+ +++ E D NWY+AE K G +P NYI + P+P+ ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D++ + +QP V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPF------------------------------------------------GNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE-----QMPQQPTY----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 169 HSP 2 Score: 55.4546 bits (132), Expect = 7.405e-9 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRGD++ V +E D NW + L K+G P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. UniProt/SwissProt
Match: sp|A6QLK6|GRAP_BOVIN (GRB2-related adapter protein OS=Bos taurus OX=9913 GN=GRAP PE=2 SV=1) HSP 1 Score: 187.578 bits (475), Expect = 1.116e-57 Identity = 97/227 (42.73%), Postives = 138/227 (60.79%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
ME++AL+ F T+SD+L FNK + I++ME D NWY+AE + G VP NYIRL P+PWY SRQ AEEIL++ GAF++R SE FS+SV ++ HFK+L+D G YY+W +KF S+N+L+ F+ +I ++ + LQD +P L + R A +D+ A P +LSF+RGD+I V + D +W RGRL + G FP +YVQ
Sbjct: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGAEGFVPKNYIRLKPHPWYSGRISRQLAEEILMKRN-------HQGAFLIRESESSPGEFSVSVNYGDQVQHFKVLRDPSGKYYLWEEKFNSLNELVAFYRTTTIAKKRQVFLQDEEP--LPKPPRACFAQ-----AQFDFSAQDPSQLSFRRGDIIEVLERLDPSWWRGRLSGRIGFFPRSYVQ 213
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. UniProt/SwissProt
Match: sp|Q9CX99|GRAP_MOUSE (GRB2-related adapter protein OS=Mus musculus OX=10090 GN=Grap PE=1 SV=1) HSP 1 Score: 181.415 bits (459), Expect = 2.634e-55 Identity = 91/227 (40.09%), Postives = 137/227 (60.35%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
ME++AL+ F T+SD+L FNK + I++ME D NWY+AE + G VP NYIR+ P+PWY SRQ AEE L++ GAF++R SE FS+SV ++ HFK+L++ G Y++W +KF S+N+L++F+ +I R+ + L D +P L++ R A +D+ A P +LS +RGD++ V +ED +W RGR + G FP +YVQ
Sbjct: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGAEGFVPKNYIRVKPHPWYSGRISRQLAEETLMKRNHL-------GAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNELVDFYRTTTIAKRRQIFLCDEQP--LIKPSRACFAQ-----AQFDFSAQDPSQLSLRRGDIVEVVEREDPHWWRGRAGGRLGFFPRSYVQ 213
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. UniProt/SwissProt
Match: sp|Q13588|GRAP_HUMAN (GRB2-related adapter protein OS=Homo sapiens OX=9606 GN=GRAP PE=1 SV=1) HSP 1 Score: 179.874 bits (455), Expect = 1.223e-54 Identity = 90/227 (39.65%), Postives = 139/227 (61.23%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
ME++AL+ F T+SD+L FNK + I++ME D NWY+AE + G +P NYIR+ P+PWY SRQ AEEIL++ GAF++R SE FS+SV ++ HFK+L++ G Y++W +KF S+N+L++F+ +I ++ + L+D +P ++ P + A +D+ A P +LSF+RGD+I V + D +W RGR + G FP +YVQ
Sbjct: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPWYSGRISRQLAEEILMKRNHL-------GAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEP-----LLKSPGACFAQ--AQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQ 213
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. UniProt/SwissProt
Match: sp|Q08012|GRAP_DROME (Protein enhancer of sevenless 2B OS=Drosophila melanogaster OX=7227 GN=drk PE=1 SV=1) HSP 1 Score: 172.555 bits (436), Expect = 6.516e-52 Identity = 90/226 (39.82%), Postives = 128/226 (56.64%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA HDF T D+L F K I+ I++ME D NWYRAE K GL+P NYI + + WY +R AE++L + +GAF++R SE FSLSVK + HFK+L+D +++W KF S+N+L+E+H S+ + + L+DM P ++ V A YD+ EL F+RGDVI VT + D NW G + +++G+FP YV
Sbjct: 1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRITRADAEKLLSN--------KHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEML------------VQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYV 206
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. UniProt/SwissProt
Match: sp|Q6YKA8|DRK_DROSI (Protein E(sev)2B OS=Drosophila simulans OX=7240 GN=drk PE=3 SV=1) HSP 1 Score: 172.555 bits (436), Expect = 6.516e-52 Identity = 90/226 (39.82%), Postives = 128/226 (56.64%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA HDF T D+L F K I+ I++ME D NWYRAE K GL+P NYI + + WY +R AE++L + +GAF++R SE FSLSVK + HFK+L+D +++W KF S+N+L+E+H S+ + + L+DM P ++ V A YD+ EL F+RGDVI VT + D NW G + +++G+FP YV
Sbjct: 1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRITRADAEKLLSN--------KHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEML------------VQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYV 206
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. TrEMBL
Match: A0A068Y1U5 (Growth factor receptor bound protein 2 OS=Echinococcus multilocularis OX=6211 PE=4 SV=1) HSP 1 Score: 238.424 bits (607), Expect = 9.496e-75 Identity = 120/231 (51.95%), Postives = 157/231 (67.97%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLES-TVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIR--QPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRD--KEGVFPFNYV 717
MEA A HDF + +D+L F K +++ I+ +E DPNWY AE + GLVP NYI PNPWY+ C R AEE LLE+ TG+ VQ DGAF++RRSE GFSLSVK ++ HFK+LQDE+G Y++W +KF SIN+LI++H + SI LLL D +PSR++ R Q + +RVIA +D+ AS P+ELSF RGDVI V G+ED NW RGR+ + G+FP NYV
Sbjct: 1 MEADAKHDFQASAADELPFCKNSVLKILSVEDDPNWYLAEQDGRKGLVPCNYISFRPNPWYMQACRRNTAEECLLETDPYTGLPVQPDGAFVVRRSESNGPGFSLSVKDGQKVQHFKVLQDEMGKYFVWLRKFDSINQLIDYHRRTSISRDGFLLLVDRQPSRMISMGRGDQQSQMVQRVIARFDFNASEPEELSFHRGDVIEVLGQEDENWWRGRISNTGSTGLFPANYV 231
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. TrEMBL
Match: A0A068WI26 (Growth factor receptor bound protein 2 OS=Echinococcus granulosus OX=6210 GN=EgrG_000587600 PE=4 SV=1) HSP 1 Score: 232.646 bits (592), Expect = 1.982e-72 Identity = 120/231 (51.95%), Postives = 156/231 (67.53%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLES-TVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIR--QPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRD--KEGVFPFNYV 717
MEA A HDF + +D+L F K +I+++ E DPNWY AE + GLVP NYI PNPWY+ C R AEE LLE+ TG+ VQ DGAF++RRSE GFSLSVK ++ HFK+LQDE+G Y++W +KF SIN+LI++H + SI LLL D +PSR++ R Q + +RVIA +D+ AS P+ELSF RGDVI V G+ED NW RGR+ + G+FP NYV
Sbjct: 1 MEADAKHDFQASAADELPFCKNSILSV---EDDPNWYLAEQDGRKGLVPCNYISFRPNPWYMQACRRNTAEECLLETDPYTGLPVQPDGAFVVRRSESNGPGFSLSVKDGQKVQHFKVLQDEMGKYFVWLRKFDSINQLIDYHRRTSISRDGFLLLVDRQPSRMISMGRGDQQSQMVQRVIARFDFNASEPEELSFHRGDVIEVLGQEDENWWRGRISNTGSTGLFPANYV 228
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. TrEMBL
Match: A0A564Y730 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS3074 PE=4 SV=1) HSP 1 Score: 231.876 bits (590), Expect = 4.417e-72 Identity = 119/231 (51.52%), Postives = 152/231 (65.80%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTV-TGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRL--VESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDK--EGVFPFNYV 717
MEA A HDF +D+L F K +++ I+ +E DPNWY AE + GLVP NYI PNPWY+ C R AEE LLE+ TG+ VQ DGAF++RRSE GFSLSVK ++ HFK+LQDE+G Y++W +KF SIN+LIE+H + SI LLL D +PSR + Q + +RVIA +D+ AS +ELSF RGDVI V G+ED NW RGR+ G+FP NYV
Sbjct: 1 MEADAKHDFQANAADELPFCKNSVLKILSVEDDPNWYLAEQDGRKGLVPCNYISFRPNPWYMQACRRNTAEECLLETDPHTGLPVQPDGAFVVRRSESNGPGFSLSVKDGQKVQHFKVLQDEMGKYFVWLRKFDSINQLIEYHRRTSISRDSFLLLVDRQPSRSMGIGGGSQQSQMVQRVIARFDFNASEAEELSFHRGDVIEVLGQEDENWWRGRISTTGATGLFPANYV 231
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. TrEMBL
Match: A0A0X3P562 (Growth factor receptor-bound protein 2 OS=Schistocephalus solidus OX=70667 GN=GRB2 PE=4 SV=1) HSP 1 Score: 231.491 bits (589), Expect = 4.743e-72 Identity = 118/229 (51.53%), Postives = 157/229 (68.56%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTV-TGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRL--RDKEGVFPFNYV 717
MEA A HDF SD+L F K I+ I+++E DPNWY AE + GLVP NYI + PNPW+ CSR RAEE LLE TG +VQ DGAF LR SE +GFSLSVK ++++HFK+LQD+ G Y+IW +F S+N+LIE+H K +I + L L D +PS+ + Q + + +RVIA +D++A+ +ELSF+RGDVI V G+ED NW +GRL D+ G+FP NYV
Sbjct: 1 MEAEAKHDFNTDASDELPFRKNTILKILNVEEDPNWYLAEQDGRRGLVPCNYIAMRPNPWFAQGCSRSRAEERLLEKDPHTGQYVQPDGAFFLRPSEAGGNGFSLSVKDGMKVLHFKVLQDDRGKYFIWMCRFDSVNQLIEYHKKTTISRDRLLTLVDPQPSKTFGNSGQ-SHSIQRVIARFDFEANDKEELSFRRGDVIEVLGREDENWWQGRLTKSDQVGLFPANYV 228
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. TrEMBL
Match: A0A0R3U5H2 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS1971 PE=4 SV=1) HSP 1 Score: 229.565 bits (584), Expect = 3.030e-71 Identity = 116/231 (50.22%), Postives = 155/231 (67.10%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTV-TGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVE--SIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDK--EGVFPFNYV 717
MEA A HDF + +D+L F K ++ I+++E DPNWY AE ++GLVP NYI PNPWY+ C R AEE LLE+ TG VQ DGAF++RRSE G+SLSVK +++HFK+LQDE G Y++W +KF S+N+LI++H + SI + LLL D +PS+L+ Q + +RVIA +D+ AS +ELSF RGDVI V G+ED NW RGR+ G+FP NYV
Sbjct: 1 MEADAKHDFQASAADELPFCKNTVLKILNVEDDPNWYLAEQDGRTGLVPCNYISFRPNPWYMQACRRNTAEECLLETDPRTGAPVQPDGAFLVRRSESNGPGYSLSVKDGQKVLHFKVLQDEFGKYFVWLRKFDSVNQLIDYHRRTSISRDRLLLLVDRQPSKLLSLGGGDQQSHMVQRVIARFDFTASESEELSFHRGDVIEVLGQEDENWWRGRISSTGATGLFPANYV 231
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Cavefish
Match: grb2b (growth factor receptor-bound protein 2 [Source:NCBI gene;Acc:111191028]) HSP 1 Score: 168.318 bits (425), Expect = 4.549e-51 Identity = 85/226 (37.61%), Postives = 125/226 (55.31%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEAIA +DF T D+L F + ++ +++ E D NWY+AE K G +P NYI + +PW+ R RAEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D I Q + V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAIAKYDFKATADDELSFKRGEVLKVLNEECDQNWYKAELNGKDGFIPKNYIEMKAHPWFFGRIPRARAEELLNKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRD---------IEQVTQHPTYVQALFDFDPQEDGELGFRRGDFIQVLDNSDPNWWKGACHGQTGMFPRNYV 210 HSP 2 Score: 54.299 bits (129), Expect = 2.382e-8 Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
IA YD++A++ DELSFKRG+V+ V +E D NW + L K+G P NY++
Sbjct: 3 AIAKYDFKATADDELSFKRGEVLKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Cavefish
Match: grb2a (growth factor receptor-bound protein 2 [Source:NCBI gene;Acc:103046713]) HSP 1 Score: 167.933 bits (424), Expect = 6.286e-51 Identity = 84/230 (36.52%), Postives = 126/230 (54.78%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ*IT 729
MEA+A +DF T D+L F + + +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N L+++H S+ + + L+D I Q + V A +D+ EL F+RGD + V D NW +G + G+FP NYV +T
Sbjct: 1 MEAVAKYDFNATADDELSFRRGETLKVLNEECDQNWYKAELNGKEGFIPKNYIEMKPHPWFYGKIPRAKAEEMLNKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNSLVDYHRSTSVSRNQPIFLRD---------IEQVPQHSTYVQALFDFDPQEEGELGFRRGDFVQVLDNSDPNWWKGACHGQTGMFPRNYVTPVT 214
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Cavefish
Match: ENSAMXT00000055322.1 (growth factor receptor-bound protein 2-like [Source:NCBI gene;Acc:111188768]) HSP 1 Score: 167.933 bits (424), Expect = 6.286e-51 Identity = 84/230 (36.52%), Postives = 126/230 (54.78%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ*IT 729
MEA+A +DF T D+L F + + +++ E D NWY+AE K G +P NYI + P+PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N L+++H S+ + + L+D I Q + V A +D+ EL F+RGD + V D NW +G + G+FP NYV +T
Sbjct: 1 MEAVAKYDFNATADDELSFRRGETLKVLNEECDQNWYKAELNGKEGFIPKNYIEMKPHPWFYGKIPRAKAEEMLNKQ-------RHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNSLVDYHRSTSVSRNQPIFLRD---------IEQVPQHSTYVQALFDFDPQEEGELGFRRGDFVQVLDNSDPNWWKGACHGQTGMFPRNYVTPVT 214
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Cavefish
Match: grap2a (GRB2-related adapter protein-like [Source:NCBI gene;Acc:103029038]) HSP 1 Score: 159.458 bits (402), Expect = 1.646e-47 Identity = 85/235 (36.17%), Postives = 130/235 (55.32%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPA------MNER---RVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEA L+DF T D+L F K + I+ + D W++AE G VP NY+ W+ N R AEE L+ V GAF++R + GFS+SV+ D ++ HFK+++D G+YY+W++KF S+NKL++++ SI ++ + L+D S+ QP ++ R +V A YD+ A DEL F GD+I V + DA+W +GRL+ + G+FP NY
Sbjct: 1 MEARGLYDFNGTAEDELSFRKGDTLKILGSQDD--WFKAEMHGHEGFVPKNYVERAVPSWFQENTGRTSAEETLISREV--------GAFLIRGCQSSREGFSISVRHDSDVQHFKVMKDNKGHYYLWSEKFTSLNKLVDYYKTTSISKQREIYLRDGSRDEPRPSVPQPVNIFTPYLHPRSTLQVKAMYDFIAEEEDELGFNAGDIIEVIDRSDASWWKGRLQGRTGLFPANYT 225
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Cavefish
Match: grapb (GRB2 related adaptor protein b [Source:ZFIN;Acc:ZDB-GENE-050913-4]) HSP 1 Score: 158.688 bits (400), Expect = 1.655e-46 Identity = 91/235 (38.72%), Postives = 129/235 (54.89%), Query Frame = 1
Query: 28 TIFKMEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEIL--LESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ*I 726
+ MEA AL+ F T+ D+L F K I+ + +M+ DPNWY AE + G VP NYI + P+ W++ SRQ AE L LE GAF++R SE FS+SV + HFK+L+D +G Y+IW + F S+N+L++F+ NSI +++ L++ P RL+ R A +D+ +L F RGDVI + DA RGR R + GVFP YVQ I
Sbjct: 71 CVCLMEAEALYSFRATECDELSFQKGDILKVTNMDDDPNWYTAELSGRRGYVPKNYINVRPHAWFVGGISRQAAEGRLRPLEC----------GAFLIRESESTPGEFSVSVSYGDHVQHFKVLKDGLGQYFIWDEVFSSLNQLVDFYRINSIAKERTVFLRE--PERLLA-------RPRHAHALFDFTPHHVSQLRFLRGDVIDLLDCSDAQCWRGRCRGRVGVFPPEYVQPI 286
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Sea Lamprey
Match: grb2a (growth factor receptor-bound protein 2a [Source:ZFIN;Acc:ZDB-GENE-041121-1]) HSP 1 Score: 172.555 bits (436), Expect = 2.289e-53 Identity = 84/226 (37.17%), Postives = 127/226 (56.19%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEA+A +DF T D+L F + ++ +++ + D NWY+AE + G +P NYI + P+PW+ R +AEE+L DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+E+H S+ + + L+DM+ + P RV A +D++ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAVAKYDFNATAEDELSFKRGDVLKVLNEDCDQNWYKAELNGRDGFIPKNYIDMKPHPWFTGKIPRVKAEEMLNRQKF-------DGAFLVRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVEYHRSTSVSRTQQIFLRDME--------QLPQQAATRVQALFDFEPQEDGELGFRRGDFITVVDSSDPNWWKGSCHGRAGMFPRNYV 211 HSP 2 Score: 47.7506 bits (112), Expect = 7.162e-7 Identity = 20/51 (39.22%), Postives = 31/51 (60.78%), Query Frame = 1
Query: 52 ALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRL 204
AL DF P + +LGF + I ++D SDPNW++ ++G+ P NY+ L
Sbjct: 164 ALFDFEPQEDGELGFRRGDFITVVD-SSDPNWWKGSCHGRAGMFPRNYVTL 213
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Sea Lamprey
Match: frk (fyn-related Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-110411-7]) HSP 1 Score: 69.707 bits (169), Expect = 9.744e-14 Identity = 49/178 (27.53%), Postives = 93/178 (52.25%), Query Frame = 1
Query: 49 IALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKS---------GLVPFNYI----RLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQ-DEVGNYYIWAQ-KFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVES 537
+AL+D+ ++DL F + ++ + D +++ +W+ A+ K S G +P NY+ L PW+ + R AE+ LL V + GAF++R+SE + +SLSV+ + H++I Q DE G ++I + F ++ +L++++ NS L + KP ++E+
Sbjct: 2 VALYDYDGRTNEDLSFKEGELLEVTD-KTNSDWWYAQKKTASTSNERYNTRGYIPANYVAEYQSLDAEPWFFGDIKRADAEKYLLAD------VNTTGAFLIRQSESRKTDYSLSVRDGSTVKHYRIRQLDENGGFFISRRVTFQNLIELVQYYKSNS----DGLCMALQKPCVVIEA 168
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Sea Lamprey
Match: ncf2 (neutrophil cytosolic factor 2 [Source:ZFIN;Acc:ZDB-GENE-070209-29]) HSP 1 Score: 60.077 bits (144), Expect = 1.684e-10 Identity = 33/85 (38.82%), Postives = 47/85 (55.29%), Query Frame = 1
Query: 493 SLLLQDMKPSRLVES----IRQP---AMNER---RVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
+L Q ++ RL+ QP A +ER RV+A DY A P +L F+ GD+I V + +ANWL GR R G+FP ++V
Sbjct: 460 TLCCQQLREPRLLPCQPPHTSQPGEAAADERVLRRVVALCDYDAKEPGDLGFREGDIIRVISEVNANWLEGRCRGNVGIFPTSFV 544
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Sea Lamprey
Match: abl1 (c-abl oncogene 1, non-receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-100812-9]) HSP 1 Score: 59.6918 bits (143), Expect = 2.677e-10 Identity = 39/144 (27.08%), Postives = 69/144 (47.92%), Query Frame = 1
Query: 49 IALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYI----RLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQ-KFGSINKLIEFH 465
+AL+DFV + + L K + ++ + W + G VP NYI L + WY SR A E LL S + +G+F+LR SE S+S++ + + H++I G Y++ ++ +F ++ +L+ H
Sbjct: 42 VALYDFVASGDNTLSITKGEKLRVLGYNQNGEWCEVHSRNGQGWVPSNYITPVNSLEKHSWYHGPISRN-AAEYLLSSGI-------NGSFLLRESESSPGQLSISLRCEGRVYHYRINTASDGKYFVSSESRFSTLAELVHHH 177
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Sea Lamprey
Match: hck (HCK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-090313-72]) HSP 1 Score: 59.3066 bits (142), Expect = 2.715e-10 Identity = 56/177 (31.64%), Postives = 83/177 (46.89%), Query Frame = 1
Query: 49 IALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKS--GLVPFNYI----RLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIM------HFKILQDEVGNYYIWAQ-KFGSINKLIEFHYKNSIHNRKSLL--LQDMKPSRLVE 534
+AL+DF + DD+GF K + II + W+ AE S G +P NY+ L W+ SR+ E +LL S GA++LR SE +SLSV+ D +I H+KI + G Y+I A+ F + LI+ + +S + LL KP +L E
Sbjct: 4 VALYDFEQLNPDDMGFKKGDKMRIIQERGE--WWMAELMDGSHKGYIPSNYVAKANSLETEEWFFSGVSRKEGERLLLAPG------NSIGAYLLRDSESNKGSYSLSVR-DYDITNGDVVRHYKIRTLDNGGYFISARLTFPDLFALIQHYTAHSDGLCQKLLRPCVSKKPQQLWE 171
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Yeast
Match: HSE1 (Subunit of the endosomal Vps27p-Hse1p complex; complex is required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes [Source:SGD;Acc:S000000994]) HSP 1 Score: 59.6918 bits (143), Expect = 1.342e-10 Identity = 27/52 (51.92%), Postives = 34/52 (65.38%), Query Frame = 1
Query: 562 RRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
RRV A YD + PDELSF++GDVI V + +W +G LR G+FP NYV
Sbjct: 220 RRVRALYDLTTNEPDELSFRKGDVITVLEQVYRDWWKGALRGNMGIFPLNYV 271
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Yeast
Match: YSC84 (Actin-binding protein; involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p; YSC84 has a paralog, LSB3, that arose from the whole genome duplication [Source:SGD;Acc:S000001058]) HSP 1 Score: 53.1434 bits (126), Expect = 1.620e-8 Identity = 23/53 (43.40%), Postives = 34/53 (64.15%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKEDA--NWLRGRLRDKEGVFPFNYVQ 720
+A Y++ P +L+FK+GDVI + K D+ +W GR KEG+FP NYV+
Sbjct: 414 AVALYNFAGEQPGDLAFKKGDVITILKKSDSQNDWWTGRTNGKEGIFPANYVR 466
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Yeast
Match: LSB3 (Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; protein abundance increases in response to DNA replication stress; LSB3 has a paralog, YSC84, that arose from the whole genome duplication [Source:SGD;Acc:S000002968]) HSP 1 Score: 50.447 bits (119), Expect = 1.251e-7 Identity = 21/61 (34.43%), Postives = 36/61 (59.02%), Query Frame = 1
Query: 544 QPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDA--NWLRGRLRDKEGVFPFNYVQ 720
P+ + + +A Y + +L F++GDVI + K D+ +W GR+ +EG+FP NYV+
Sbjct: 397 SPSTSSPKAVALYSFAGEESGDLPFRKGDVITILKKSDSQNDWWTGRVNGREGIFPANYVE 457
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Yeast
Match: LSB1 (Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with PIN3 cooperatively inhibits the nucleation of actin filaments; overexpression blocks receptor-mediated endocytosis; protein increases in abundance and forms nuclear foci in response to DNA replication stress; LSB1 has a paralog, PIN3, that arose from the whole genome duplication [Source:SGD;Acc:S000003368]) HSP 1 Score: 48.521 bits (114), Expect = 3.337e-7 Identity = 26/59 (44.07%), Postives = 34/59 (57.63%), Query Frame = 1
Query: 544 QPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
Q A E V A YD++A +LS K GD I V K +W RG+ +K G+FP NYV+
Sbjct: 50 QNADTEEYVEALYDFEAQQDGDLSLKTGDKIQVLEKISPDWYRGKSNNKIGIFPANYVK 108
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Yeast
Match: RVS167 (Calmodulin-binding actin-associated protein; roles in endocytic membrane tabulation and constriction, and exocytosis; N-BAR domain protein that interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; recruited to bud tips by Gyl1p and Gyp5p during polarized growth; homolog of mammalian amphiphysin [Source:SGD;Acc:S000002796]) HSP 1 Score: 49.2914 bits (116), Expect = 3.769e-7 Identity = 27/53 (50.94%), Postives = 32/53 (60.38%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVI-VVTGKEDAN-WLRGRLRDKEGVFPFNYVQ 720
V A YDYQA + +LSF G VI +V D N W GR ++GVFP NYVQ
Sbjct: 426 VTALYDYQAQAAGDLSFPAGAVIEIVQRTPDVNEWWTGRYNGQQGVFPGNYVQ 478
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Nematostella
Match: EDO38076 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE08]) HSP 1 Score: 124.405 bits (311), Expect = 8.476e-35 Identity = 75/229 (32.75%), Postives = 113/229 (49.34%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRL--RDKEGVFPFNYVQ 720
MEA A H+F T DDLGF K +I+N++DM+ D NWY+AE + G +P YI + P+ + E VQ G +R + ++ HFK+ +D YY+W KF S+NKL++ H + S+ + ++L+DM + V A +D++A E+SFKRGD I V D NW RG++ + G+FP NYV+
Sbjct: 1 MEARAKHEFKATQEDDLGFAKGSILNVLDMDQDKNWYKAEQDGREGWIPKTYIEMKPHD--------------VGEEGGNHQVVQCLGRGDHQRF-------------NNQVQHFKVFRDTDRKYYLWNTKFLSLNKLVDHHREASVSRSQHIVLKDMMEA---------------VQALFDFEAQEEGEVSFKRGDCIEVIDNSDVNWWRGKVLTTGEIGMFPSNYVK 187
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Nematostella
Match: EDO29864 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2F6]) HSP 1 Score: 91.6633 bits (226), Expect = 2.511e-23 Identity = 45/117 (38.46%), Postives = 71/117 (60.68%), Query Frame = 1
Query: 373 IMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRD--KEGVFPFNYV 717
I HFK+L+D G Y++W KF S+N+L+E+H +S+ + + L+D+ ++ V+A YD+ A EL+FK+G+ I V KED NW +GR+ + +EG+FP NYV
Sbjct: 6 IQHFKVLRDGAGKYFLWVVKFNSLNQLVEYHRTSSVSRSQQIFLKDVDSE----------CSQDTVVALYDFVAQEAGELNFKKGNHIEVLDKEDDNWWKGRVAETGEEGLFPRNYV 112
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Nematostella
Match: EDO38500 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCW1]) HSP 1 Score: 61.6178 bits (148), Expect = 4.856e-11 Identity = 47/176 (26.70%), Postives = 80/176 (45.45%), Query Frame = 1
Query: 214 PWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGR-LRDKEGVFPFNYVQ*ITCIP 738
PWY R E IL + G +++R S + + LSV + ++ H+ I+ ++ Y I Q F + +IEF+ K H + L++ P+ +V A Y + ++L FK+GD++ V KE+ NW + R +EG+ P YVQ ++ P
Sbjct: 8 PWYHGVLKRVETEGILNG--------KPPGVWLVRDSTTIPGDYVLSVSESGKVSHY-IINNKGTMYTIGDQTFPDLPSIIEFYKK---HFLDTTTLKEHVPNSECNI---------KVKALYAFPGKDDEDLPFKKGDILTVISKEEDNWWKARDSAGREGMIPKPYVQVLSNAP 162
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Nematostella
Match: EDO43872 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXM7]) HSP 1 Score: 56.9954 bits (136), Expect = 2.888e-9 Identity = 24/51 (47.06%), Postives = 35/51 (68.63%), Query Frame = 1
Query: 574 AAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ*I 726
A YDYQA+ DEL+ GD+I VT + D W +G L +++G+FP +YV+ I
Sbjct: 441 AIYDYQATQSDELTIHPGDIITVTARLDNGWWQGDLNNQQGIFPASYVEEI 491
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Nematostella
Match: EDO42689 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0K6]) HSP 1 Score: 55.8398 bits (133), Expect = 6.058e-9 Identity = 23/52 (44.23%), Postives = 37/52 (71.15%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIV-VTGKEDANWLRGRLRDKEGVFPFNYVQ 720
V+A YDY+A+ DELSFK G+++ ++ ++D W RGR+ + G+FP YV+
Sbjct: 386 VLALYDYEAAEDDELSFKAGEIVTKLSERDDQGWCRGRINHRTGLFPAEYVE 437
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Medaka
Match: grb2b (growth factor receptor bound protein 2 [Source:NCBI gene;Acc:101160816]) HSP 1 Score: 166.777 bits (421), Expect = 1.735e-50 Identity = 82/226 (36.28%), Postives = 127/226 (56.19%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEA+A +DF T D+L F + ++ +++ E D NWY+AE K G +P NYI + +PW+ R +AEE+L + + DGAF++R SE FSLSVK ++ HFK+L+D G Y++W KF S+N+L+++H S+ + + L+D++ + P + V A +D+ EL F+RGD I V D NW +G + G+FP NYV
Sbjct: 1 MEAVAKYDFKATADDELSFKRGEVLKVLNEECDQNWYKAELNGKDGFIPKNYIEMKAHPWFFGKIPRAKAEEMLNKQRL-------DGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRTTSVSRNQQIFLRDIE--------QVPQQHPTYVQALFDFDPQEEGELGFRRGDFIQVLDNSDPNWWKGGCHGQTGMFPRNYV 211 HSP 2 Score: 53.5286 bits (127), Expect = 3.628e-8 Identity = 24/52 (46.15%), Postives = 36/52 (69.23%), Query Frame = 1
Query: 568 VIAAYDYQASSPDELSFKRGDVIVVTGKE-DANWLRGRLRDKEGVFPFNYVQ 720
+A YD++A++ DELSFKRG+V+ V +E D NW + L K+G P NY++
Sbjct: 3 AVAKYDFKATADDELSFKRGEVLKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Medaka
Match: grapa (GRB2-related adapter protein [Source:NCBI gene;Acc:101160815]) HSP 1 Score: 164.466 bits (415), Expect = 1.485e-49 Identity = 92/229 (40.17%), Postives = 122/229 (53.28%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ*I 726
MEA+AL+ F T+ D+L FNK ++ I +ME DPNWY AE + G VP NYI L P+ W+ SR AE L GAF+ R SE FS+SV + HFK+LQD G YYIW + F S+N+L+EF++ NSI + + L+D P R+P A +D+ P +L F RGDVI + D+ RGR + G FP YVQ I
Sbjct: 1 MEAVALYTFRATEGDELSFNKGDMLKITNMEDDPNWYTAELHNRKGFVPKNYINLRPHAWFAGRISRGVAESRLRHREC--------GAFLARESESAPGEFSMSVSYGDHVQHFKVLQDRCGQYYIWDETFSSLNELVEFYHSNSIAKERMVFLRD--PEHFA---RRP----HHARALFDFNPHHPSQLRFLRGDVIELIDYSDSVRWRGRCHGRVGYFPPEYVQTI 212
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Medaka
Match: grap2a (growth factor receptor-bound protein 2 [Source:NCBI gene;Acc:101165394]) HSP 1 Score: 133.265 bits (334), Expect = 7.427e-37 Identity = 89/290 (30.69%), Postives = 128/290 (44.14%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQD--------------------------------------------MKPSRLVESIRQPAMNERRVIAAYDY-------QASSP-------------DELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYV 717
MEA ++F T D+L F K ++ II+ E + W +AE + G VP NY+ + W+ N SR AEEIL V G F++R + FS+SVK + ++ HFK+++D G Y++W++KF S+NKL+EF+ SI + + L+D MK S L E R A+ Y QAS+P DEL F GDVI V + D +W RGRL+ + G+FP NY
Sbjct: 1 MEARGKYEFSATADDELSFRKGDVLKIINFEEE--WCKAELNGQEGYVPKNYLEIQLPAWFQENTSRSGAEEILRHRDV--------GDFVIRGCQTSPGDFSISVKHESDVQHFKVMRDNKGQYFLWSEKFMSLNKLVEFYKTTSISKTRKICLKDGSSNSRSPASAQVKRASLPEQRNPAAAAVASSTRRASEQTPNQLMKRSGLEERAHTIGHTGRNSPASMTYPPQRAQQQASAPMVRALYDFTAEEADELGFCVGDVIEVMDRSDPSWWRGRLQGRTGLFPANYT 280 HSP 2 Score: 50.8322 bits (120), Expect = 5.555e-7 Identity = 22/52 (42.31%), Postives = 34/52 (65.38%), Query Frame = 1
Query: 52 ALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLL 207
AL+DF ++D+LGF +I ++D SDP+W+R + ++GL P NY LL
Sbjct: 233 ALYDFTAEEADELGFCVGDVIEVMD-RSDPSWWRGRLQGRTGLFPANYTVLL 283
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Medaka
Match: grapb (GRB2-related adapter protein [Source:NCBI gene;Acc:101166194]) HSP 1 Score: 126.331 bits (316), Expect = 2.509e-34 Identity = 85/268 (31.72%), Postives = 120/268 (44.78%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMN-----------------------------------------ERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
MEA+AL F +++D+L F K I+ + +ME D W AE + + G VP NYI LLP+PW+ SR AE+ L Q G F++R+SE FS SV + HF++L+ G Y IW + F S+N+L++F+ +SI K + L+D S V+S PA N R A DY L F RGDVI + + RGR R + G+FP +V
Sbjct: 1 MEAVALFSFSASEADELSFQKGDIVKVTEMEEDSYWVIAEIQGRRGFVPVNYISLLPHPWFAGAVSRLEAEQHLR--------WQVTGVFLVRQSESAPGEFSFSVSYGDRVEHFRVLEGG-GQYCIWDKAFCSLNRLVDFYRTHSIAVEKVVCLRDAPSSPRVQS--HPARNPYPSPHRHSSQESISSAHLHSRPCYPERDSSLNLQKPFLEMPRLANALCDYTPDQTTHLHFLRGDVIELLDCSSSLGWRGRCRGRVGIFPPKFVH 257
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Medaka
Match: vav2 (vav guanine nucleotide exchange factor 2 [Source:NCBI gene;Acc:101175178]) HSP 1 Score: 79.337 bits (194), Expect = 4.324e-16 Identity = 62/242 (25.62%), Postives = 108/242 (44.63%), Query Frame = 1
Query: 70 PTDSDDLGFNKEAIINIIDMESDPNWY--RAEYKQKSGLVPFNYIRLLPNP------------WYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMK-PSRLVE------SIRQPAMNERRV---IAAYDYQASSPDELSFKRGDVIVVTGK--EDANWLRGRLRDKEGVFPFNYV 717
P L F II ++ + D W+ R QKSG P + ++ +P W+ N RQ+A+ +L S G +++R + F++S+K + E+ H K+++ + + A+KF S+ +L+E++ +S+ LL ++ P + E S R P R V +A Y++ A ELS + GD++ + K D W +G + G FP YV
Sbjct: 589 PLGKTPLCFQTGEIIELLKGDPDTTWWEGRLIQTQKSGFFPSSCVKPCLDPKVQFSCTAGAQAWFAGNMERQQADNLLKS--------HSSGTYLIRERTAEAERFAISIKFNDEVKHIKVIEKDSWIHITEAKKFESLLELVEYYQSHSLKESFKLLDTTLRYPYKSRERSLTRASTRSPVFTPRVVSTAVARYNFAARDMRELSLREGDIVKIYSKIGGDQGWWKGEANGRIGWFPSTYV 822
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Planmine SMEST
Match: SMESG000077597.1 (SMESG000077597.1) HSP 1 Score: 471.085 bits (1211), Expect = 2.367e-170 Identity = 227/227 (100.00%), Postives = 227/227 (100.00%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 720
MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ
Sbjct: 1 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSIHNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ 227
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Planmine SMEST
Match: SMESG000007565.1 (SMESG000007565.1) HSP 1 Score: 198.749 bits (504), Expect = 7.541e-63 Identity = 104/233 (44.64%), Postives = 151/233 (64.81%), Query Frame = 1
Query: 40 MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIRLLPNPWYLPNCSRQRAEEILLEST-VTGMFVQSDGAFILRRSELLSSGFSLSVKQDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNSI--HNRKSLLLQDMKPSRLVESIRQPAMNERRVIAAYDYQASSPDELSFKRGDVIVVTGKEDANWLRGRLRDKEGVFPFNYVQ*IT 729
MEAI L++F + D+L F K + + I++ME DPNW++AE K+GLVP NYI ++P+PWY+P CSR AE LLE + +Q DGAF++R+S FSLSVK + E++HF+IL +E + IW++ F S+NKLI+FH +S+ ++ L+L++ PS+ QP+ IA +D+ S +ELSFK GDVI G+ED NW G L+ + G+FP NYVQ +T
Sbjct: 1 MEAIGLYNFNSKEPDELSFVKGSQLKILNMEDDPNWFKAECDNKTGLVPANYIEMIPHPWYVPYCSRVEAENRLLECGDSSNQSIQPDGAFLIRQSVNSKGLFSLSVKSENEVIHFRILCNENYKFSIWSELFSSLNKLIDFHMVHSVCKDDQPKLVLRNRVPSK---KFCQPSAC-GYFIAQFDFNGLSSEELSFKHGDVIKKVGEEDVNWWIGELKGRRGIFPSNYVQKVT 229
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Planmine SMEST
Match: SMESG000016115.1 (SMESG000016115.1) HSP 1 Score: 64.3142 bits (155), Expect = 3.957e-12 Identity = 45/149 (30.20%), Postives = 75/149 (50.34%), Query Frame = 1
Query: 52 ALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAE-YKQKSGLVPFNYIRLLP-----NPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVK-QDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNS 477
AL++F ++DL F+K + ++ + SDPNW KQ GLVP N+++L P +PWY SR AEE L+ +G F++R S+ +++ VK D++ H ++ G F S+ +LIE + K++
Sbjct: 11 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPC--------ENGTFLIRSSDKFPGDYTICVKFNDVQFYH--VIYSNKGYTLDEDSWFASMPELIEHYQKDA 149
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Planmine SMEST
Match: SMESG000016115.1 (SMESG000016115.1) HSP 1 Score: 65.0846 bits (157), Expect = 1.335e-11 Identity = 45/149 (30.20%), Postives = 75/149 (50.34%), Query Frame = 1
Query: 52 ALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAE-YKQKSGLVPFNYIRLLP-----NPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSVK-QDLEIMHFKILQDEVGNYYIWAQKFGSINKLIEFHYKNS 477
AL++F ++DL F+K + ++ + SDPNW KQ GLVP N+++L P +PWY SR AEE L+ +G F++R S+ +++ VK D++ H ++ G F S+ +LIE + K++
Sbjct: 11 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPC--------ENGTFLIRSSDKFPGDYTICVKFNDVQFYH--VIYSNKGYTLDEDSWFASMPELIEHYQKDA 149
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Planmine SMEST
Match: SMESG000032667.1 (SMESG000032667.1) HSP 1 Score: 59.3066 bits (142), Expect = 1.087e-9 Identity = 44/154 (28.57%), Postives = 73/154 (47.40%), Query Frame = 1
Query: 46 AIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFNYIR----LLPNPWYLPNCSRQRAEEILLESTVTGMFVQSDGAFILRRSELLSSGFSLSV--KQ--DLEIMHFKILQDEVGNYYIWAQK--FGSINKLIEFHYKNS 477
+AL+ F P + L K +ID WY + + G VP ++++ + W+ + SRQ+AE L E +G FI+R S +G +LSV KQ L + H++I Q V + ++K + S+ +LIE+H N+
Sbjct: 177 VVALYSFTPIQTGQLQLVKGERYTLIDCSHPDWWYMRDNYGEMGYVPRSHVQREDNFCNHDWFYGDVSRQQAESQLYEEG-------REGCFIVRCSSTGDTGLTLSVLTKQSGSLRVHHYRIRQQGVSGPFYLSEKHLWPSVTELIEYHKHNA 323 The following BLAST results are available for this feature:
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Class E vacuolar protein-sorting machinery protein HSE1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008280 ID=SMED30008280|Name=Class E vacuolar protein-sorting machinery protein HSE1|organism=Schmidtea mediterranea sexual|type=transcript|length=890bpback to top protein sequence of SMED30008280-orf-1 >SMED30008280-orf-1 ID=SMED30008280-orf-1|Name=SMED30008280-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=228bp MEAIALHDFVPTDSDDLGFNKEAIINIIDMESDPNWYRAEYKQKSGLVPFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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