Retrovirus-related Pol polyprotein LINE-1

Overview
NameRetrovirus-related Pol polyprotein LINE-1
Smed IDSMED30008223
Length (bp)2854
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Retrovirus-related Pol polyprotein LINE-1 (SMED30008223) t-SNE clustered cells

Violin plots show distribution of expression levels for Retrovirus-related Pol polyprotein LINE-1 (SMED30008223) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Retrovirus-related Pol polyprotein LINE-1 (SMED30008223) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Retrovirus-related Pol polyprotein LINE-1 (SMED30008223) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008223

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30008223 SmedASXL_007527SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
zeta neoblastSMED30008223 dd_Smed_v4_18284_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Zebrafish
Match: CU462878.3 (pep chromosome:GRCz11:17:8542203:8545189:1 gene:ENSDARG00000103562.2 transcript:ENSDART00000158873.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CU462878.3)

HSP 1 Score: 60.077 bits (144), Expect = 1.388e-8
Identity = 68/276 (24.64%), Postives = 120/276 (43.48%), Query Frame = 2 
Query:  116 FNNIFRNRKFPKQWKRFKTKLILIKGKE-NELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWIT------KGGFLCANQ------KAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQ-----LYIHDHNVNILAHSDCIVLMSDSKEGITSILN--STIEFADMADLKFIPSKCGYYQLHKNQETK 883
            FN + R  + P+ W+     +I  +GK+ NE S   S+RPI  L+  YK+F +IL+ +L   I+      + GF+   Q      + + I S     N+              +  ++ LD    F  +  + ++  + + G N K  E IK ++   +   +  NG   S  I + RG  QGCPLS TLF L I  +   +  E +     +   +H + + A  D ++ +++ K  I  +++  +TI F     +    ++   Y    N E K
Sbjct:  310 FNYVLRGGEIPQSWQEAVISIIPKQGKDKNECS---SYRPISVLNVDYKLFASILSKRLEVVISELVDLDQTGFIQNRQTQDNLRRTLQIMSHITTENI--------------SAMLLSLDAEKAFDSVGWDYLYQVLARFGFNNKFIECIKGLYLSPKAKIKI-NG-HLSKTIYLERGTRQGCPLSPTLFALFIEPLAQAIREEPEIKGIVIKKEEHKICMYA-DDVLLFLANPKSSIPKLMSLLNTINFYSGYKINIQKTQTLTYNFRPNLEMK 565
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Zebrafish
Match: CABZ01033394.1 (pep chromosome:GRCz11:13:6032844:6038477:-1 gene:ENSDARG00000101795.2 transcript:ENSDART00000166130.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01033394.1)

HSP 1 Score: 54.6842 bits (130), Expect = 5.888e-7
Identity = 55/252 (21.83%), Postives = 110/252 (43.65%), Query Frame = 2 
Query:   74 WRIVGPDKKCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYV-SRENQLYIHDHNV--NILAHSDCIVLMSDSKEGITSILNSTIEFADMA 820
            W ++G D     A+ N        P   +R    L+  KG   +L +  +WRP+  L   +KI    L  +L   I  G  +  +Q          ++  ++    + S     +L ++ +D    F  + H  +W T++  G       +IK ++Q + +  +   G      IN  RGI QGC LS  L+ L+I  +L  + SR     + + +V   + A++D +++  + ++ + ++++   EF  ++
Sbjct:  510 WDVLGED---FLAVLNESLTEGSLPLSCRRAVVTLLPKKG---DLQEIKNWRPVSLLCSDFKILSKTLANRLKNVI--GHIIHPDQTYCVPGRSIMDNISLVRDILDLSSYFNLDLGLISIDQEKAFDRVEHQYLWNTLEAFGFGSGFIGMIKVLYQDIESVLKINGGLSAPFKIN--RGIRQGCALSGMLYSLAIEPMLRKLRSRIEGFMLANKSVQHQLSAYADDVIVFVNGQKDVNTLVSIISEFDKLS 751
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Zebrafish
Match: CT956002.2 (pep chromosome:GRCz11:4:64279882:64284924:-1 gene:ENSDARG00000102873.2 transcript:ENSDART00000166733.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CT956002.2)

HSP 1 Score: 54.299 bits (129), Expect = 9.014e-7
Identity = 62/238 (26.05%), Postives = 104/238 (43.70%), Query Frame = 2 
Query:  173 KLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITS-GCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQ---LYIHDHNVN--ILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHK 868
            KLI  KG++  L +   +RPI  L+   KI   IL  +L   + K   +    +A  I     A+  M I    EY    K+  +I+ LD    F  + H  ++  + K G  +  R+ IK +++G+ T  +  NG   +    I R I QGCPLS  L+ L    +   ++ E +   + I ++ VN  +  ++D   L+   KE +   +    +F   +  K    K  Y +  K
Sbjct:  516 KLIHKKGEKTLLKN---YRPITMLNTDLKILTKILANRLKEVMPK---IIKTTQAYAIKGRDIADITMSIKDIIEYMKEKKEEGYIISLDFEKAFDRVEHQFLFKVLKKFGFGEVFRKWIKILYKGILTKVKC-NGF-LTECFKITRSIRQGCPLSALLYSLVAEPLGLAINEEEKIKGIEIEENKVNKKMFQYADDTTLIVKGKESVKEAMKIVQQFCKGSGSKVNEDKTVYMKFGK 745
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Zebrafish
Match: si:dkeyp-88h4.2 (si:dkeyp-88h4.2 [Source:ZFIN;Acc:ZDB-GENE-131121-105])

HSP 1 Score: 51.9878 bits (123), Expect = 3.350e-6
Identity = 65/284 (22.89%), Postives = 113/284 (39.79%), Query Frame = 2 
Query:  212 DPT---SWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSG--CAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLY---IHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLH 1039
            DPT   +WRPI  L+  YK+  +I   +L     +      N+   G   G   + +  ++    +Y      +  I++LD    F  + H  +  ++   G   K   +++ +++ + +     +    S    + RGI QGCPLS  LF   +  +   +   N L    I +  + I   +D   L    K+ ++ +L     F+D + LK    KC    L+   + K+    E IP+  E    KY G N                LS++K I +S L 
Sbjct:   62 DPTIIDNWRPITLLNFDYKLLASIFAKRL----KRHLHYIINETQTGFIKGRHISCNTRLVLDLIDYKNEIDSDAIILFLDFYKAFDTVKHEFLLDSLKAFGFPLKFLNVVQMLYKDINSCVILNSCT--SPRFPVLRGIRQGCPLSPFLFLFVVETLSIDILHNNNLVGINIFNREIRISQLADDTTLFLKDKDQVSPVLTIINAFSDASGLKLNLLKCEIICLYDTLDAKI----ENIPIKEE---VKYLGINITKNLISRQFLNFSTRLSKVKYIFNSWLQ 332
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Zebrafish
Match: CU024870.2 (pep chromosome:GRCz11:25:23489979:23495448:1 gene:ENSDARG00000103841.2 transcript:ENSDART00000158200.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CU024870.2)

HSP 1 Score: 51.6026 bits (122), Expect = 4.796e-6
Identity = 65/284 (22.89%), Postives = 113/284 (39.79%), Query Frame = 2 
Query:  212 DPT---SWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSG--CAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLY---IHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLH 1039
            DPT   +WRPI  L+  YK+  +I   +L     +      N+   G   G   + +  ++    +Y      +  I++LD    F  + H  +  ++   G   K   +++ +++ + +     +    S    + RGI QGCPLS  LF   +  +   +   N L    I +  + I   +D   L    K+ ++ +L     F+D + LK    KC    L+   + K+    E IP+  E    KY G N                LS++K I +S L 
Sbjct:  527 DPTIIDNWRPITLLNFDYKLLASIFAKRL----KRHLHYIINETQTGFIKGRHISCNTRLVLDLIDYKNEIDSDAIILFLDFYKAFDTVKHEFLLDSLKAFGFPLKFLNVVQMLYKDINSCVILNSCT--SPRFPVLRGIRQGCPLSPFLFLFVVETLSIDILHNNNLVGINIFNREIRISQLADDTTLFLKDKDQVSPVLTIINAFSDASGLKLNLLKCEIICLYDTLDAKI----ENIPIKEE---VKYLGINITKNLISRQFLNFSTRLSKVKYIFNSWLQ 797
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Xenopus
Match: bmi1 (BMI1 proto-oncogene, polycomb ring finger [Source:Xenbase;Acc:XB-GENE-942188])

HSP 1 Score: 58.151 bits (139), Expect = 3.390e-8
Identity = 56/220 (25.45%), Postives = 100/220 (45.45%), Query Frame = 2 
Query:  161 RFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSI--RNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYI---LDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIE 805
            R  + ++L KGK++E  +  +WRPI  L+   KI   +   +L+ +   G  L   Q   G   G +    ++TI +   +     K  +IV LD    F  + H  +W T+ K G+  K  + +  +++G  ++    NG  + +  N+  G+ QGCPLS  L+  +I+     L+              +  LA++D + ++  S  G   +LN  IE
Sbjct:  117 RVSSLILLSKGKDSERIE--NWRPIALLNNDRKILARVFFDRLIQF--SGTLLSGFQ--FGTVKGRSIFGALLTIRETLEVCKAQSKGCYIVSLDQAKAFDRVNHEYLWSTLGKYGIPGKFIQWLAVLYEGAVSF-PLVNGW-RGDDFNVESGVRQGCPLSPLLYVFAIDPFLRSLESCGLRGMSIPRCQTLASLAYADDVTVVV-SSPGDRRLLNEAIE 327
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Xenopus
Match: ENSXETT00000039541.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:1:4874907:4875967:-1 gene:ENSXETG00000012548.1 transcript:ENSXETT00000039541.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.6102 bits (135), Expect = 9.727e-8
Identity = 47/185 (25.41%), Postives = 80/185 (43.24%), Query Frame = 2 
Query:  116 FNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAV--GITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSIN 664
            +N   R  + P+   +    L+   GK+  L  P S+RPI  L    KI   +L  +L   I  G  +  +Q     G T+      + + +   ++  N     I  LDI   F  +    +W  +DK G   K   L+K +++    + +   G +++   ++ RG  QGCPLS  LF ++I 
Sbjct:  132 YNEAHREGQLPQSMYQAAIVLLPKAGKDPTL--PESYRPISLLTADVKILAKLLANRLKKII--GSIIADDQLGFMPGKTTAMNIRRLFLNLTTAHA--NSGERAIAALDIAKAFDTVEWPYLWKALDKFGFGTKFVNLVKLLYKSPTAFLRV--GTDEAPPFSLTRGTLQGCPLSPLLFAIAIE 308
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Xenopus
Match: ENSXETT00000025099.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV461626.1:454:2734:-1 gene:ENSXETG00000014681.1 transcript:ENSXETT00000025099.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.225 bits (134), Expect = 2.364e-7
Identity = 55/219 (25.11%), Postives = 99/219 (45.21%), Query Frame = 2 
Query:  161 RFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSI--RNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYI---LDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTI 802
            R  + ++L KGK++E  +  +WRPI  L+   KI   +   +L+ +   G  L   Q   G   G +    ++TI +   +     K  +IV LD    F  + H  +W T+ K G+  K  + +  +++G  ++    NG  + +  N+  G+ QGCPLS  L+  +I+     L+              +  LA++D + ++  S  G   +LN  I
Sbjct:  231 RVSSLILLSKGKDSERIE--NWRPIALLNNDRKILARVFFDRLIQF--SGTLLSGFQ--FGTVKGRSIFGALLTIRETLEVCKAQSKGCYIVSLDQAKAFDRVNHEYLWSTLGKYGIPGKFIQWLAVLYEGAVSF-PLVNG-WRGDDFNVESGVRQGCPLSPLLYVFAIDPFLRSLESCGLRGMSIPRCQTLASLAYADDVTVVVSSP-GDRRLLNEAI 440
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Xenopus
Match: ENSXETT00000032317.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:1:130520927:130524992:-1 gene:ENSXETG00000008594.1 transcript:ENSXETT00000032317.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 5.574e-7
Identity = 64/269 (23.79%), Postives = 112/269 (41.64%), Query Frame = 2 
Query:  113 LFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKG------GFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIF---RGINQGCPLSITLFRLSINYILDYVSRENQLYIHDH-----NVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQE 877
            LF    +  +FP+        L+  +GK+  L +  S+RPI  L    KIF  +L  +L   ITK       GF+ A       T+      + + +A   + +  K   I  LDI   F  +    +W  +   G  KK  ++++ +++     Y   + +  S     F   RG  QGCPLS  LF ++I      V    Q+   ++      V + A  D +V + D    +T++ + T +F  ++ L+   +K   + + K Q 
Sbjct:  491 LFKEAVQLGQFPESLYEAAIVLLPKQGKDPHLCE--SFRPISLLTADVKIFAKVLARRLSRVITKIIHPDQIGFIPAK------TAALNTRRLYLNLAHASAGQGAKA--IAALDITKAFDTVEWPYLWQVLTHFGFGKKYIQMVQLLYK-----YPVASIRINSLTTPAFALSRGTRQGCPLSPLLFAIAIEPFAQAVRAHPQITGFEYPGFNEKVQLYA-DDTLVYLGDRGPSLTALTDLTQKFGRISGLQTSMAKSVLFLVDKQQP 743
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Xenopus
Match: ENSXETT00000036577.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV460393.1:598533:603041:-1 gene:ENSXETG00000016126.1 transcript:ENSXETT00000036577.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.0694 bits (131), Expect = 6.887e-7
Identity = 64/316 (20.25%), Postives = 133/316 (42.09%), Query Frame = 2 
Query:   53 GKLTIADWRIVGPDKKCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKK-NLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSD------SKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKV----TMHDEEIPLINEQNFYKYFGENFGYKG 967
             +L +A W ++GPD   +  L+  +    K P+  +  +  + ++  ++ +  D  +WRPI  L+  YKI   +L  +L   I   G +    +  GI       ++ +     + I++++ +  +V LD    F  + H  +   + + GL +     +  M++ + +     NG  K+++  +  G+ QGCPLS  LF   I    + + R  ++          +   C + M D       ++ + S++ +  +F+  +  K     CG        ET +     +  + +P   + +F K  G  FG +G
Sbjct:  470 AELYVALWDLIGPD---LLELYEEMAVEGKMPQSLR--EGMITILYKQKGDRCDLKNWRPISLLNVDYKILAKVLANRLKTVI---GQIVHPDQTCGIPERRIADSLALIRDTVHYIKDRRVHAALVSLDQEKAFDRVSHVFMNKVLRRFGLGEMFCSYVSLMYRDIFSLV-LVNG-WKTDLFPVLSGVRQGCPLSPLLFVCCIELFAECIRRNPEIRGITAPGPARSQIKCSLYMDDVTVFCADQQSVRSLVQTCEDFSKASGAKV---NCG------KSETLLFGDWNLASDNVPFSIKADFIKILGVWFGGEG 766
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. UniProt/SwissProt
Match: sp|P16423|POLR_DROME (Retrovirus-related Pol polyprotein from type-2 retrotransposable element R2DM OS=Drosophila melanogaster OX=7227 GN=pol PE=4 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 6.574e-18
Identity = 94/403 (23.33%), Postives = 174/403 (43.18%), Query Frame = 2 
Query:  215 PTSWRPIPKLDPLYKIFLAILNYKL---LGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKVTMHD--------EEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLG---DDSENIHDYFLYGSSSLGCLGIVPSIDEYCIQSIIHLLRMLN------TNDNKLRKFFEKE 1363
            P  +RPI     L +   AIL  +L   + W  +       Q+    T GCA++  I+ +   +S ++ ++ +I  LD++  F  L H  I+ T+   G  K   + ++  ++G  T    +    +  V    RG+ QG PLS  LF L ++ +L  +  E    + +   N  A +D +VL ++++ G+  +L+ T++F  +  LK    KC    +    + K T+ +         EIP +   + +KY G NF   G+    N  +    +++ +  + L P Q+  A R  +  +L   L   SV            +G  +K  KL++ ++    +   ++   F++     G LGI PS+    +  ++ L R+ N      T +     F E E
Sbjct:  412 PQDFRPISVPSVLVRQLNAILATRLNSSINWDPR-------QRGFLPTDGCADNATIVDLVLRHSHKHFRSCYIANLDVSKAFDSLSHASIYDTLRAYGAPKGFVDYVQNTYEGGGTSLNGDGWSSEEFVPA--RGVKQGDPLSPILFNLVMDRLLRTLPSEIGAKVGNAITNAAAFADDLVLFAETRMGLQVLLDKTLDFLSIVGLKLNADKCFTVGIKGQPKQKCTVLEAQSFYVGSSEIPSLKRTDEWKYLGINFTATGRVRC-NPAEDIGPKLQRLTKAPLKPQQRLFALRTVLIPQLYHKLALGSV-----------AIGVLRKTDKLIRYYVRRWLNLPLDVPIAFVHAPPKSGGLGI-PSL--RWVAPMLRLRRLSNIKWPHLTQNEVASSFLEAE 790
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. UniProt/SwissProt
Match: sp|Q03278|PO21_NASVI (Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Fragment) OS=Nasonia vitripennis OX=7425 PE=4 SV=2)

HSP 1 Score: 89.3521 bits (220), Expect = 8.949e-17
Identity = 85/353 (24.08%), Postives = 154/353 (43.63%), Query Frame = 2 
Query:   98 KCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQL---HKNQETKVTMH------DEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAY-----RKFIHLELIFPLQNSSV 1114
            +CI++LFN I  + + P+++   +T LI    KE    DP  +RP+       + F  IL  +    I + G L   Q+A  +  G AE+  +++   + +    K L+I  LD+   F  + H  I   + +  L  + R  I  +++  +T  + E  K K   I   RG+ QG PLS  LF   ++ +L  +       +    +  L  +D +VL+++++EG+ + L+          L+ +P KC    L    K ++ KV  H      ++EI  +   + +KY G  +   G   +   +   L R+     + L P Q+          +FIH  ++    N+ V
Sbjct:  350 ECIKSLFNMIMYHGQCPRRYLDSRTVLI---PKEPGTMDPACFRPLSIASVALRHFHRILANR----IGEHGLLDTRQRAFIVADGVAENTSLLSAMIKEARMKIKGLYIAILDVKKAFDSVEHRSILDALRRKKLPLEMRNYIMWVYRNSKT--RLEVVKTKGRWIRPARGVRQGDPLSPLLFNCVMDAVLRRLPENTGFLMGAEKIGALVFADDLVLLAETREGLQASLSRIEAGLQEQGLEMMPRKCHTLALVPSGKEKKIKVETHKPFTVGNQEITQLGHADQWKYLGVVYNSYGPIQVKINIAGDLQRVTA---APLKPQQRMAILGMFLIPRFIHKLVLGRTSNADV 690
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. UniProt/SwissProt
Match: sp|Q03279|PO21_BRACO (Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Fragment) OS=Bradysia coprophila OX=38358 PE=4 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 2.939e-11
Identity = 99/432 (22.92%), Postives = 168/432 (38.89%), Query Frame = 2 
Query:  212 DPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETK---------VTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFI---HLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFL---GDDSENIHDYFLYGSSSLGCLGIVPSIDEYCIQSIIHLLRML------NTNDNKLRKFFEKELFDIIGNNGEDSSISKALEWINNESGS 1444
            DP  +RP+     + + F  IL  + +   T      A     G+   C   +M+  I  E + R +K LHI  LD+   F  + H+ +   + + G      + I +M+  V T  QFE    K  + +I  G+ QG PLS  LF L+    L  ++ E +  I D  VN  A+SD  +L++ +  G+   L+   E      L+    K     L  +   K         + +   E+  +   + +KY G  +   G       MD  LS++       L P Q+ H  + F+   HL  +          V+           D  + K ++ +L   GD    +   FLY     G  GI       C++  I L+R L       T  +++      +L+  I ++ +   +S  L W +  +G 
Sbjct:  226 DPGVFRPLSICSVILREFNKILARRFVSCYTYDERQTAYLPIDGV---CINVSMLTAIIAE-AKRLRKELHIAILDLVKAFNSVYHSALIDAITEAGCPPGVVDYIADMYNNVITEMQFEG---KCELASILAGVYQGDPLSGPLFTLAYEKALRALNNEGRFDIADVRVNASAYSDDGLLLAMTVIGLQHNLDKFGETLAKIGLRINSRKSKTVSLVPSGREKKMKIVSNRRLLLKASELKPLTISDLWKYLGVVYTTSGPEVAKVSMDDDLSKLT---KGPLKPQQRIHLLKTFVIPKHLNRL----------VLSRTTATGLCKMDLLIRKYVRRWLRLPGD----VPVAFLYAPVKAGGKGIP------CLKQWIPLMRFLRLNKAKRTGGDRIAAVLNCQLYASISHSCKTGPVSVGL-WRSTNTGG 626
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. UniProt/SwissProt
Match: sp|Q03274|PO22_POPJA (Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Fragment) OS=Popillia japonica OX=7064 PE=4 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 1.659e-9
Identity = 78/336 (23.21%), Postives = 145/336 (43.15%), Query Frame = 2 
Query:  146 PKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQL--YIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKN-----QETKVTMHDEEI--PLINEQNFYKYFGENFGYKG--KYDMGNLMDKALSR-IKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVN 1117
            P  W   +T LI    K+ +L +P++WRPI     L ++   IL  +L   +     L   QK      G   +++++          +K  ++V LD+   F  + H+ I   + ++G+++ T   I        T  +   G + +  I I RG+ QG PLS  LF   ++ +L  +     +   I +  + +LA +D ++L+ D+   + + L +   F  +  +     K     +  +       TK  +  + +  P+ +    ++Y G  FG  G  K  + N     LSR +K +  + L P QK    R+ +  +L++ LQN SV 
Sbjct:   53 PTPWTAMRTTLI---PKDGDLENPSNWRPITIASALQRLLHRILAKRLEAAVE----LHPAQKGYARIDGTLVNSLLLDTYISSRREQRKTYNVVSLDVRKAFDTVSHSSICRALQRLGIDEGTSNYITGSLSDSTTTIRVGPGSQ-TRKICIRRGVKQGDPLSPFLFNAVLDELLCSLQSTPGIGGTIGEEKIPVLAFADDLLLLEDNDVLLPTTLATVANFFRLRGMSLNAKKSVSISVAASGGVCIPRTKPFLRVDNVLLPVTDRMQTFRYLGHFFGLSGAAKPTVYN-----LSRWLKCVEAAPLKPEQKLSLIREHVVPKLLYGLQNPSVT 375
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. TrEMBL
Match: A0A131XRS2 (Putative reverse transcriptase (Fragment) OS=Ixodes ricinus OX=34613 PE=2 SV=1)

HSP 1 Score: 213.386 bits (542), Expect = 1.089e-53
Identity = 193/784 (24.62%), Postives = 345/784 (44.01%), Query Frame = 2 
Query:   56 KLTIADWRIVGPDKKCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKVTMHDEE-------IPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLGDDSENIHDYFLYGSSSLGCLGIVPSIDEYCIQSIIHLLRMLNTNDNKLRKFFEKELFDIIGNN-GEDSSISKALEWINNESGSDREEAHGNMFVKYRYSVRAIRDKFNIIIKLKNENEKYIIEIKFLDSKCHLNCEKLKDKFTIIHEM---IGLIYTQKWLQLENPVKI-----ARPAGIIWVTSYLINTIELDDANYFFLINARNNVLDLNYSPSRLKKGLNVDCRLCKMEYETQKHIFNNCIEGIITRENAFNNVRKTVSDYFLNKGFNFYVKKAFPGVGAISQPDLIIIKSNRNETLNILIINVQYDSNQH-FERIRDENYQKYKDVVAELEKRNNCKTTLALLVVGALGSWDSDNDNVLKVMGLTDSEIRELIELSTMAAVNASYNIYMNHL 2356
            +LT   W  V PD + + A FN   + R  P  W++ +T L+  KG   E+   TSWRPI  L    K+F  +L  +L  W+ +   L   QK      G  EHN ++    + +     +L   +LD +N F  +PHN I   V  +G  +   EL+++M+    +     +G   ++ I +  GI QGCPLS  LF    N ++D V R+ Q    DH   ILA++D +  ++     + + +N   E A    L    +KC    LH +  + V +   +       IP+I +   + Y G   G+    D G+ +D A+     IL S+L P Q+  A + F++  L   ++  +V        + E    D+ L  L+K  L       +DY +YGSS  G  GI  + +   +  +  + ++L + D ++ +    EL  I+      D  +  A  +++  +  D       +   +    R    + N+  +L  E     +  + +           + +  ++H +   +  +   +   L N  K+     A PAG  ++ + L        A++ F+  AR N+L LN +    ++G +  CR C    ET  H+ N+C+          NNV + V      + F    + A  G   + +PDL+++   R E   ++ + + +++ +    + R    +KY+ V+  L +R   + T+  +VVGALGSWD  ND  LK +  + S ++ + +++    + AS +IY  H+
Sbjct:  127 RLTYHHWLAVDPDCRFLTAAFNICLQYRAIPDSWRQSRTILVPKKGDPAEI---TSWRPISLLRTASKLFSGVLAARLQAWLLEHDVLSRTQKGFLPYDGVFEHNYVLQRRMDEARTTSGDLCAAFLDFSNAFGCVPHNAIVDAVRGVGAGEAFAELVQDMYYESSSSVVTNDG--CTDPIPMRCGIRQGCPLSGLLF----NLVVDPVIRKVQGTTADH--RILAYADDLTPLARDPASLQASINLIEEEAGRLGLTLNAAKC--RSLHLSGCSPVGLRGSQFLVNGTPIPVIRDFEAFAYLGRPVGFNILQD-GSDVDAAIQLGTRILGSMLAPWQRLDAIKMFLYPALHHLMRTGTVG-------KTEWARLDEALRPLIKRTLYLPPGASNDY-IYGSSRAGACGIPCAAETSDVCRVDSVFKLLTSRDPEVARMALDELMGIVKARLRRDCDLPDAELYLSGHNEGDFRMPATQLRSVWTEG-RKASGRLNVAWELGPEGASITVGSQVITP---------RGRSKVMHSLRFQLAQLKDARLHALPNQGKVMECVAADPAGSHFIRTGLYTRF----ADWRFIHRARLNLLPLNGA-QPWRRGGDQRCRRCGFASETLPHVLNHCMRQSQAITQRHNNVVERVKKASAGR-FTLVSENAAVGDTHL-RPDLVLV---RGEEAVVVDVCIPFENRKEALVQARRTKEEKYRPVIDHLRRRYQ-RVTVEAVVVGALGSWDPANDRFLKKL-CSRSYLKRMKQMAASDTIRASRDIYAAHI 866
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. TrEMBL
Match: A0A2G5S9Z3 (Reverse transcriptase domain-containing protein OS=Caenorhabditis nigoni OX=1611254 GN=B9Z55_028893 PE=4 SV=1)

HSP 1 Score: 201.06 bits (510), Expect = 1.873e-49
Identity = 196/789 (24.84%), Postives = 344/789 (43.60%), Query Frame = 2 
Query:   89 PDKKCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSI-NYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQ---ETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLGDDSENIHDYFLYGSSSLGCLGIVPSIDEYCIQSIIHLLRMLNTNDNKLRKFFEKELFDII-GNNG-EDSSISKALEWINNESGSDREEAHGNMFVKYRYSVRAI---RD----KFNIIIK----------LKNENEKYIIEIKFLDSKCHLNCEKLKDKFTIIHEMIGLIYTQKWLQLENPVKIARPAGIIWVTSYLINTIELDD----ANYFFLINARNNVLDLNYSPSRLKKGLNVDCRLCKMEYETQKHIFNNCIEG----IITRENAFNNVRKTVSDYFLNKGFNFYVKKAFPGVGAISQPDLIIIKSNRNETLNILIINVQYDSN-QHFERIRDENYQKYKDVVAELEKRNNCKTTLALLVVGALGSWDSDNDNVLKVMGLTDSEIRELIELSTMAAVNASYNIYMNHLH 2359
            P  K +  L+N    +R+ P  WK  +T L+   G E   S P +WRPI  +  +YK++ ++ N ++    +  G +   Q+      GC E   I+  A + +   K NL + WLD+ N F  +PH +I +T++  G  +   ++I +M++G     + +N  EKS+ I I  G+ QG P+S TLF + + N I  ++   N     +  V +LA +D + ++S+SK  + + L    E     +L F P+KC    + K +   + ++ +  + I  + E++ YKY G   G + +     LM  A   ++ +  S L P QK    R F+  ++ F   NS   P +      E   +     + +K   G   +     ++      G LGI        I  ++ +++ L + D  + K F + L  +     G ED+++    E+++NE   D++    N F + R   R +   +D    K  I++K          +K+  EK   E +  + +  L  E       ++H             +E PVK +    +I         ++LD     A   F+  AR N+L  NY  +     ++  CR C  E E+Q HI + C  G    I  R +A     K + +    K +  ++ +  PG   + +PD I +KS   + + +  + V Y+   +  +R  D   +KY D  A L K      ++  +VVGALG+W       L+ +G+    IR  I       +  S N Y NH++
Sbjct:  133 PSSKFLTLLYNECKEHRRIPAHWKEAETVLLYKGGDE---SKPENWRPISLMPTIYKLYSSLWNRRIR---SIKGIMSRCQRGFQEREGCNESIGILRAAIDVAKGKKSNLSVAWLDLTNAFGSVPHELIKHTLETYGFPEIVVQIIMDMYKGAAIRVKSKN--EKSDRILIKSGVKQGDPISPTLFNMCLENVIRRHLETANGHKCLNTRVKVLAFADDMAILSESKTQLQNELLKMDEDCTPLNLIFKPAKCASLVIEKGRVKSDAEIKLKSQSIRCLTEKDTYKYLGVQTGIETRKSELELMKSATKELEMVYRSKLTPPQKLDCVRTFVLPKMSFMYANSV--PKL-----TELKAFANMTMRAVKMMHGIPVKGSPVEYVQLPVGKGGLGIACPKITALITYLVSMMKKLWSKDRYIEKLFSEYLKKVAEAETGIEDATLEDMAEYLSNEKPVDKKAFGYNSFTRIREVCRGLCGNKDSPLFKIKIVVKDGKLAILTQAIKDGKEKVFTEERVKNLQALLKAEVTT---ALLHR----------FNVEKPVK-SEVCRVIQQYPQCNKFVKLDGKVSYAAQRFVHKARLNLLACNY--NTYSDVVSKACRHCGYERESQWHIISKCNFGMPRKITQRHDAVLFKVKKLIESGSKKDWELHIDETPPGPNRL-RPD-IYMKSPDGKQIILADVTVPYEHGVEAMQRAWDRKVEKYTDSFAHL-KVGGASLSVLPIVVGALGTWWKPTSKSLEQLGIEKGVIRRAIPEICSTVLEYSKNAYWNHIY 887
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. TrEMBL
Match: A0A2G5SAA7 (Reverse transcriptase domain-containing protein OS=Caenorhabditis nigoni OX=1611254 GN=B9Z55_028808 PE=4 SV=1)

HSP 1 Score: 199.519 bits (506), Expect = 3.178e-49
Identity = 192/777 (24.71%), Postives = 341/777 (43.89%), Query Frame = 2 
Query:   89 PDKKCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSI-NYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQ---ETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLGDDSENIHDYFLYGSSSLGCLGIVPSIDEYCIQSIIHLLRMLNTNDNKLRKFFEKELFDII-GNNG-EDSSISKALEWINNESGSDREEAHGNMFVKYRYSVRAI---RDKFNIIIKLKNENEKYIIEIKFL-DSKCHLNCEKLKDKFTIIHEMIGLIYTQKWLQLENPVKIARPAGIIWVTSYLINTIELDD----ANYFFLINARNNVLDLNYSPSRLKKGLNVDCRLCKMEYETQKHIFNNCIEG----IITRENAFNNVRKTVSDYFLNKGFNFYVKKAFPGVGAISQPDLIIIKSNRNETLNILIINVQYDSN-QHFERIRDENYQKYKDVVAELEKRNNCKTTLALLVVGALGSWDSDNDNVLKVMGLTDSEIRELIELSTMAAVNASYNIYMNHLHS 2362
            P  K +  L+N    +R+ P  WK  +T L+   G E   S P +WRPI  +  +YK++ ++ N ++    +  G +   Q+      GC E   I+  A + +   K NL + WLD+ N F  +PH +I +T++  G  +   ++I +M++G     + +N  EKS+ I I  G+ QG P+S TLF + + N I  ++   N     +  V +LA +D + ++S+SK  + + L    E     +L F P+KC    + K +   + ++ +  + I  + E++ YKY G   G + +     LM  A   ++ +  S L P QK    R F+  ++ +   NS   P +      E   +     + +K   G   +     ++      G LGI        I  ++ +++ L + D  + K F + L  +     G ED+++    E+++NE   D++    N F + R   R +   +D     IK+  ++ K  I  + + D K  +  E+       + +       Q    +E PVK +    +I         ++LD     A   F+  AR N+L  NY  +     ++  CR C  E E+Q HI + C  G    I  R +A     K + +    K +  ++ +  PG   + +PD I +KS   + + +  + V Y+   +  +R  D   +KY D  A L K      ++  +VVG LG+W       L+ +G+    IR  I       +  S N Y NH++ 
Sbjct:   41 PSSKFLTLLYNECKEHRRIPAHWKEAETVLLYKGGDE---SKPENWRPISLMPTIYKLYSSLWNRRIR---SIKGIMSRCQRGFQEREGCNESIGILRAAIDVAKGKKSNLSVAWLDLTNAFGSVPHELIKHTLETYGFPEIVVQIIMDMYKGAAIRVKSKN--EKSDRILIKSGVKQGDPISPTLFNMCLENVIRRHLETANGHKCLNTRVKVLAFADDMAILSESKTQLQNELLKMDEDCTPLNLIFKPAKCASLVIEKGRVKSDAEIKLKSQSIRCLTEKDTYKYLGVQTGIETRKSELELMKSATKELEMVYRSKLTPPQKLDCVRTFVLPKMSYMYANSV--PKL-----TELKAFANMTMRAVKMMHGIPVKGSPVEYVQLPVGKGGLGIACPKITALITYLVSMMKKLWSKDKYIEKLFSEYLKKVAEAETGIEDATLEDMAEYLSNEKPVDKKAFGYNSFTRIREVCRGLCGNKDSPLFKIKIVVKDGKLAILTQAIKDGKEKIFTEERVKNLQALLKAEVTTALQHRFNVEKPVK-SEVCRVIQQYPQCNKFVKLDGKVSYAAQRFVHKARLNLLACNY--NTYSDVVSKACRHCGYERESQWHIISKCNFGMPRKITQRHDAVLFKVKKLIESGSKKDWELHIDETPPGPNRL-RPD-IYMKSPDGKQIILADVTVPYEHGVEAMQRAWDRKVEKYTDSFAHL-KVGGASLSVLPIVVGTLGTWWKPTSKSLEQLGIEIGVIRRAIPEICSTVLEYSKNAYWNHIYG 796
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. TrEMBL
Match: A0A4D5S5F8 (Putative reverse transcriptase (Fragment) OS=Ixodes scapularis OX=6945 PE=4 SV=1)

HSP 1 Score: 197.978 bits (502), Expect = 2.709e-48
Identity = 188/783 (24.01%), Postives = 344/783 (43.93%), Query Frame = 2 
Query:   56 KLTIADWRIVGPDKKCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLH-----KNQETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLGDDSENIHDY-FLYGSSSLGCLGIVPSIDEYCIQSIIHLLRMLNTNDNKLRKFFEKELFDIIGNNGEDSSISKALE-WINNESGSDREEAHGNMFVKYRYSVRAIRDKFNIIIKLKNENEKYIIEIKFLDSKCHLNCEKLKDKFTIIHEMIGLIYTQKWLQLENPVKIARPAGIIWV---TSYLINTIELDD-ANYFFLINARNNVLDLNYSPSRLKKGLNVDCRLCKMEYETQKHIFNNCI---EGIITRENAFNNVRKTVSDYFLNKGFNFYVKKAFPGVGAIS-QPDLIIIKSNRNETLNILIINVQYDSNQ-HFERIRDENYQKYKDVVAELEKRNNCKTTLALLVVGALGSWDSDNDNVLKVMGLTDSEIRELIELSTMAAVNASYNIYMNHL 2356
            +LT   W+ V PD   + A++N   R+R+ P  WK  +T LI  KG      DPT+WRPI     + K++   L  +L  W+++   L   QK      G  EHN ++    + +  +   L + +LD  N F  + HN +   V   G  +    ++++++Q   T    E G   +  I+I  GI QGCPLS  LF    N +LD V R  Q     H  NILA++D +  ++D  + +   +N+    +    LK  P+KC    L        + T  T+ +  IP I +   + + G   GY+   D   + D A++  K +L S+L P Q+  A + F+   L F ++  ++        +++    D+ L  LLK  L   S + ++Y +   ++    + +   I + C   I    ++L++ D ++R      + DI        +    +E ++  ++  D       +   +  + +A R +  +  +L+ +  +    I F ++         K +  +I  +  ++  +K   L+      +    +     +S+ I + +    A++ F+  AR N+L LN +       ++  CR C  + ET  H+  +C+     I  R N      K V          F V      VG    +PDL+++   R E   +L +   +++ +   +  R +  +KY   V EL +R   + T+  +VVGALG+WD DND +L+ +  + S +R + +L     +  S +IY+ H+
Sbjct:  307 RLTYHHWKTVDPDACFLTAVYNICLRHRRVPAIWKETRTILIYKKGDRQ---DPTNWRPISLGCTIAKLYAGCLASRLQDWMSEHSVLSRCQKGFLPHDGVFEHNFVLQERLDRARTSGGQLCVAFLDFANAFGSVAHNALIEAVRGAGAGEAFASIVQDLYQDNITTVAAEEG--TTEPISIAAGIRQGCPLSGLLF----NLVLDPVIRAVQGGERRH--NILAYADDLTPLADDPDMLQQRINTVAALSGRLGLKLNPAKCRTIHLTGEHPVGTRPTTFTIDESPIPTIGDFTGHSFLGRPVGYRVLADNATIRD-AINLGKRLLTSVLAPWQRLDAVKTFLFPALNFAMRAGTLG-------KEDWRRLDETLRPLLKRTLYLPSNSSNEYLYGGAAAGAVGIPVAADISDAC--RIDGAFKLLSSPDPEIRSMALLAVTDITAKRLRRPAAEGDIEAYLTGKTEGDFRSTATQLKPVWTEARKASR-RLGVSWELRPDGAR----IAFGETSL-----SPKHRHKVIRTLREVLMAEKNAALQQKPSQGKAMECVAADRTSSHFIRSGQFTRFADWRFIHRARLNLLPLNGA-RPWAAAVDQRCRTCGYQQETLPHVVCHCMPRSRDITERHN------KIVRRIKAAATSRFTVTHEDQSVGDTGLRPDLVLV---RGEEAIVLDVCCPFENRRVAMQEARAKKIEKYAP-VRELLRRRFQRVTVEAVVVGALGAWDPDNDKILRRL-CSRSYLRLMKKLIVSETIAKSRDIYVAHV 1046
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. TrEMBL
Match: A0A4Y2UBZ6 (Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 OS=Araneus ventricosus OX=182803 GN=PO21_35 PE=4 SV=1)

HSP 1 Score: 197.208 bits (500), Expect = 1.164e-47
Identity = 206/786 (26.21%), Postives = 348/786 (44.27%), Query Frame = 2 
Query:   56 KLTIADWRIVGPDKKCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLH-----KNQETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLGDDSENIHDYFLYGSSSLGCLGIVPSIDEYC-IQSIIHLLRMLNTNDNKLRKFFEKELFDIIGNNGEDSSISKA-LEWINNESGSDREEAHGNMFVKYRYSVRAIRD--KFN---IIIKLKNENEKYIIEIKFLDSKCHLNCEKLKDKFTIIHEMIGLIYTQKWLQLENPVKIARPAGIIWVTSYLINTIELDDANYFFLINARNNVLDLNYSPSRLKKGLNVDCRLC-KMEYETQKHIFNNCIEGIITRENAFNNVRKTVSD----YFLNKGFNFYVKKAFPGVGAISQPDLIIIKSNRNETLNILIINVQYDSN-QHFERIRDENYQKYKDVVAELEKRNNCKTTLALLVVGALGSWDSDNDN-VLKVMGLTDSEIRELIELSTMAAVNASYNIYMNHL 2356
            +LT   W+ +      +  +FN     RK P  WK   T LI    K   L+DP +WRPI     +YK+F   L  +L  W+ K   L   QK      G  EHN ++  + E + + KK+L I +LDI+N F  LPH+ I   ++   +     ++IK+++ G  T    E+G   S  I I  G+ QGCP+S  LF + I    D V RE Q    +H   ILA +D + L++ S   + + L+      +  +LK  P KC  + L        ++T   +    +  + +  F K+ G+  G+    +  +L D      K +++S L    +  A + FI+    FP++ S          +K     D+ L K +K  L       +DY LYG    G   I P + E C +  +    ++L + D K++    + L   +    +  S+S A LE   + +  D + A  N F   R +   ++   +FN     +KL++      + IK  D K  L    L+D+F  +     L+  ++   +E   K       ++   Y    +      Y F  +AR ++L L  +    KK  ++ CR C + + ET  H+ N+C +G   R  A+      V+D      L KG      +    +G   +PDL+       + + I+ + + +++  + FER R E   KY+ +V +  K +  K T+  ++VG+LGSWD  ND  +LKVM  + S + +  +L     +  S  I++ H+
Sbjct: 1228 RLTYFHWKSLESSSLFLSTVFNACLHFRKIPPSWKLSSTILI---PKAGNLNDPVNWRPIALSSTIYKLFTKCLASRLTQWLEKYDILSPCQKGFTPFDGVVEHNYVLQRSIELARKRKKDLCIAFLDISNAFGSLPHSTIIDALNACAVGPAFVDIIKDIYSGATTKVLSESGATDS--IPILSGVKQGCPISGILFDICI----DPVIREIQGSHSEH--RILAFADDVCLLAPSVVELQAQLDRIDVLFNSLNLKLNPKKCVSFHLSGAKPAGARDTSFFIDRTRLTSLKDGEFTKFLGKPVGFNPCPNYSSLND-MYEAAKAVMESGLSQWMRIDALKSFIYPAFQFPMRTSQF-------PKKAWHSIDKALRKSIKQTLSLPERASNDY-LYGHRKFGSYAI-PILAEECELNRLDSAFKLLTSKDEKIKIMALEHLSSTVRARMQKDSVSDADLEAYLSATFHDNDNAFSNTFTCARIASSRLKVHWQFNDGAPTLKLED------LTIKPSDRKKVLF--SLRDRFRTMRSNRLLLCPKQGKAMECVAKSTASTHFLFSGEYTSFAV------YRFFGSARLDLLSLRGN-QPWKKNTDMSCRGCDECDLETLPHVLNHC-KG---RSRAWTLRHNCVADRLKKALLTKGTLLAENQCVGPLG--KRPDLVF---QIGKEIYIIDVTIPFENRYESFERARQEKIDKYQHLVDQYAK-DGVKATVVPIIVGSLGSWDPKNDKFLLKVM--SKSYLNKFRKLCCSDVLEWSRKIFVEHV 1965
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Cavefish
Match: ENSAMXT00000031340.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000052.1:450620:454069:1 gene:ENSAMXG00000031773.1 transcript:ENSAMXT00000031340.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 84.7297 bits (208), Expect = 3.570e-16
Identity = 84/318 (26.42%), Postives = 140/318 (44.03%), Query Frame = 2 
Query:  113 LFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMII-TIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYI---LDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKVTMHDEEIPLINEQNF-----YKYFGENFGYKGKYDMG--NLMDKALSRIKTILDSL 1033
            LFN I     FP  W      LI    K  +  +P ++R I     L KIF +ILN ++  ++ +   L  NQ         ++H   + T+  ++  +NK  +   ++D    F  + H  ++Y + + G+  +T ++IK M+   +   + EN   +++     RG+ QGC LS TLF L IN +   LD  S    L + D  V  L ++D +VL+S ++EG+   L    +F     LK    K       K  +++  ++ +    IN  N      Y Y G  F   G + +    L +KA   I  I  S+
Sbjct:  541 LFNFILNVGHFPTMWNE---GLITPIFKTGDKFNPNNYRGICVSSNLGKIFCSILNSRITQFLIEHDVLSKNQIGFLPNHRTSDHIFTLHTLIDKHVTQNKHKIFTCFVDFQKAFDSIWHTGLFYKLIENGVGGRTYDVIKSMYSQSKCAVKIEN--LRTDFFPQSRGVRQGCSLSPTLFNLYINELAEKLDQSSNIPGLTLGDTEVKCLLYADDLVLLSPTREGLQQSLEMLEDFCHTWALKINHQKTKIMVFQKGTKSQGNLNFK----INNTNIEYTKTYTYLGITFSCTGSFGLAVKELKEKARRAIFAIKKSV 849
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Cavefish
Match: ENSAMXT00000033573.1 (pep primary_assembly:Astyanax_mexicanus-2.0:3:31407009:31410218:-1 gene:ENSAMXG00000030324.1 transcript:ENSAMXT00000033573.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.6481 bits (200), Expect = 2.784e-15
Identity = 95/424 (22.41%), Postives = 183/424 (43.16%), Query Frame = 2 
Query:  113 LFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGI--TSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQF----ENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVS---RENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQ---ETKVTMHDEEIPLINEQNFYKYFGENF--GYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLGDDSENIHDYFLYGSSSLGCLGIVPSIDEYCIQSIIHLLRMLNTNDNKL 1342
            +   I+R  K  +QW RF   + + K + ++  D   +R I  L    KIF +IL  +L  +++   ++  + +  GI    GC EH  ++T     +  NK +L ++WLD+ N +  +PH ++  T+++  +  +  ELI      +  Y QF      G   S    +  GI  GC +S+ LF L++N ++       R  +         + A  D + + ++S  G   IL    E    A ++F P K     L + +   + + ++    IP ++E+   K  G+ F    K    +     +  S ++ +  S L    K   Y+  I   +++PL    V   I         G ++K+S  L+ +LG    ++    LYG ++   L +    +E+ +     ++   +++D K+
Sbjct:  298 ILKVIWRRGKVARQW-RFAEGVWIPKEEVSKNID--QFRIISLLSVEGKIFFSILARRLTDFLSSNHYIDTSVQKGGIPGVPGCLEHTGVVTQLIREARENKGDLAVLWLDLANAYGSIPHKLVQTTLERHHVPGQVAELI------MNYYDQFSMRVSTGSITSEWHRVEVGIITGCTISVILFVLAMNMLVKSAETQCRGPKTMTGVRQPPVRAFMDDLTITTESVPGSRWILQGLEELCGWARMRFKPEKSRSLVLKRGKVVDKFRFSIGGASIPTVSEKPV-KSLGKEFNSSLKDSVSVQGTCQELESWLRAVDRSGLPGKFKAWIYQHGILPRVLWPLLVYEVPISIVE-------GLERKVSSFLRRWLG-LPRSLSSIALYGRNTKLQLPLRSLEEEFKVTRAREVMMYRDSSDPKV 703
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Cavefish
Match: ENSAMXT00000034831.1 (pep primary_assembly:Astyanax_mexicanus-2.0:3:16211297:16215948:1 gene:ENSAMXG00000034228.1 transcript:ENSAMXT00000034831.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 75.0998 bits (183), Expect = 3.096e-13
Identity = 83/371 (22.37%), Postives = 163/371 (43.94%), Query Frame = 2 
Query:  113 LFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGIT--SGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYIL---DYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQ--ETKVTMHDEEIPLINEQNFYKYFGENF--GYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLG 1198
            L   +++    PK+W R    LI    KE +      +RPI  L+   KIF +++  +L  ++ +   +  + +  GI   SGC EHN +I    + +   KK+LH+V+LD+ N F  +PH ++W   +   + ++   L+K   + ++  + F  G+  ++   +  GI  GC +S+  F +++  I+    +V    +L+       + A  D +  ++ +      +L    +   +A +K  PSK     + K +  + +  M  E IP I E+   K  G  +      K  +  L  + +  I  I  S L    K    +  +   L +PL        +++    E    ++ +SK ++++LG
Sbjct:  413 LMAIVWKKGIIPKEWHRAGGVLI---PKEKDSVAIDQFRPISLLNVEGKIFFSVVARRLATYLKRNNLIDTSVQKAGIAGFSGCIEHNSMIWHQIQTARAEKKDLHVVFLDLANAFGSVPHALLWKAFNFFRVPEEISRLVKAYFEDIQ--FCFSVGECVTSWQRLEIGIMAGCTISLLAFTMAMEVIIRASKWVVGGERLHDGTRLPPVRAFMDDMTTLTTTVPCTRRLLGKLNDNLRLARMKVKPSKSRSVSIVKGKLIQERFMMEGEVIPSILEKPI-KSLGRWYTAALNDKEQVEGLRTEMVEAINRIDKSFLPGKLKLWCLQFGLLPRLRWPL-------TVYDIPISEVERLERVMSKAIRTWLG 770
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Cavefish
Match: ENSAMXT00000055550.1 (pep primary_assembly:Astyanax_mexicanus-2.0:1:16555187:16560144:-1 gene:ENSAMXG00000035203.1 transcript:ENSAMXT00000055550.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.1738 bits (178), Expect = 1.117e-12
Identity = 73/335 (21.79%), Postives = 147/335 (43.88%), Query Frame = 2 
Query:  125 IFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGIT--SGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYIL---DYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKVTMHDEE--IPLINE---QNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPL 1099
            ++  +  PK W+R    LI    KE + S+   +R I  L+   K+F +I+  +L  ++ +   +  + +  GI   SGC EH  +I    + + +  ++LH+++LD+ N F  +PH++IW   D   +      +++   Q ++   Q          + +  GI  GC +S   F +++  I+    +V    +L        I A+ D +  ++ +      +L    +  D A ++F PSK     + K +      H +E  IPL++E   ++  +++  N   K       L  + +  + +I  +LL    K    +  +   L++PL
Sbjct:  360 MWTKQTIPKAWRRAGGVLI---PKEKDASNIGQFRQINLLNVEGKVFFSIVAKRLTKYLKENNMIDTSVQKAGIPGFSGCLEHISMIWHQIQSARKEGRDLHVLFLDLANAFGSIPHSLIWAAFDFFHIPNTITNMVRNYFQDLQFCIQTTEYTTSWQSLEV--GIMAGCTISPLAFTMAMEVIIRASKWVVGGERLQSGHRLPPIRAYMDDLTTLTSTVACTKQLLGKLQDNIDWARMRFKPSKSRSLSISKGKLVDQRFHIKETPIPLVSELPVKSLGRWY--NASLKDSDQADQLRKETIKGLASIDKTLLPGRLKLWCLQFGLLPRLMWPL 687
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Cavefish
Match: ENSAMXT00000029797.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:11908834:11912265:1 gene:ENSAMXG00000039541.1 transcript:ENSAMXT00000029797.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.5514 bits (166), Expect = 2.660e-11
Identity = 73/346 (21.10%), Postives = 141/346 (40.75%), Query Frame = 2 
Query:  113 LFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITS--GCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYY---QFENGKEKSNVINIFRGINQGCPLSITLFRLSINYIL---DYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHK---NQETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQ-KFHAYRKFIHLELIFPLQNSSV 1114
            L   +++N+  P +W+      I    KE   +  + +R I  L+   KIF  +L  ++  ++    ++  + +  G+    GC EH  +I    + + R K +LH+VWLD+ N +  +PH ++ + ++   +      +I +    +R  +    F  G ++  V     GI  GC +S  LF  +   IL     V+R  +         +  + D +  +  +      +L    E    A +K   SK     + K   +  T  +   E+IPL+ EQ       E         MG ++ + L      ++S   P + K   Y+  +   +++PL+   V
Sbjct:  378 LMRVVWKNKSVPAEWQEAVGIFI---PKEQNSTTTSQFRSIALLNVEGKIFFTVLARRIAQFLKSNSYIDTSCQKAGLPGFPGCIEHATMIWEQIQRAKREKSDLHVVWLDMANAYGSVPHKLVEFALEFFYIPDCIITIIGKYFSNLRMSFVMDGFATGWQQLEV-----GIAMGCSISPILFVAAFEVILIGARQVARGLKTPEGGRFPALRGYMDDVTSILQTAPCTARLLKRLEELTMWARMKIKSSKSRSLSIRKGVRDDRTVFSAGGEKIPLLAEQPIRSLGREYTAELSDRQMGTMIQRQLREGLIKINSSQLPGKLKVWCYQFTLFQRVMWPLKVCEV 715
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Medaka
Match: ENSORLT00000037842.1 (pep primary_assembly:ASM223467v1:6:23612405:23615659:1 gene:ENSORLG00000030391.1 transcript:ENSORLT00000037842.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.337 bits (194), Expect = 1.305e-14
Identity = 83/418 (19.86%), Postives = 181/418 (43.30%), Query Frame = 2 
Query:   77 RIVGPDK------KCI--------RALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQL-HKNQETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALS-------RIKTILDSLLHPTQ-KFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLGDDS-ENIHDYFLYGSSSLGCL 1258
            + VGPD       KC+          LFN I  + K P++W+R  + L+ I   + ++ + +++R I  +    K++  ++  +L     K   +C  Q          +    + + +E     +K LH V++D+   +  +P   +WY +   G+ +K   ++++M++   T  +   G+ +   + +  G++QG  LS  LF + ++ + D V +E+           +  +D IV+ S+S+E +   L       +   +K   SK  Y  L  K+Q   V +   E+  + E   +KY G    + G  + G  + + +        ++  +L     P + K   Y+  +   L++ L+  +V        ++++   +    K+L+  LG    + I + ++ G++ + C+
Sbjct:  529 KAVGPDDVPVEVWKCLGETAVEFLTRLFNRILESEKMPEEWRR--SVLVPIFKNKGDMQNCSNYRGIKLMSHTMKLWERVVEARL----RKKVEICEQQYGFMPRKSTTDAIFALRMLREKYREGQKELHCVFVDLEKAYDRVPREELWYCMRSSGVAEKYVRVVQDMYERSMTVVRCAVGQTEEFKVEV--GLHQGSALSPFLFAMLMDRLTDEVRQESPW--------TMMFADDIVICSESREQVEEQLERWRFALERRGMKVSRSKTEYMCLNEKDQGRSVRLQGAEVKKVQE---FKYLGSTVQWDG--ECGKEVKRRVQAGWSGWRKVSGVLCDRKVPARLKGKVYKTVVRPALLYGLETVAVR-------QRQEAEMEVAEMKMLRFSLGVTRLDRIRNEYIRGTAHVACV 918
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Medaka
Match: ENSORLT00000043092.1 (pep primary_assembly:ASM223467v1:4:30731179:30734007:-1 gene:ENSORLG00000025660.1 transcript:ENSORLT00000043092.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.9518 bits (193), Expect = 1.628e-14
Identity = 102/423 (24.11%), Postives = 185/423 (43.74%), Query Frame = 2 
Query:   65 IADWRIVGPD-------KKC------IRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMII--TIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNI--LAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQ---ETKVTMHDEEIPLINEQNFYKYFG--ENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLGDDSENIHDYFLYGSSSLGCLGIV 1267
            + +W   GPD       KK       + A  N + R+   P+     +T  ILI+   ++ + P+++RPI  L P +K+   I+  K+   + +  F+   QK +G  S  A+H +++  T+A++   R+  NL   W+D    +  +PH  I   ++   +N+  R  I    + ++T  +  NGK  + V +I  G  QG  LS  LF + +N +   +++    Y   +  NI  L + D I L + S+  I S++++T  ++    + F   KC      + +      V++ +  I  I  ++ YKY G  +  G   +        K L R++ +L S L+   K  A   +    + +P         I    ++E    D K  KLL    G  +++ +   LY S   G  G+V
Sbjct:  124 MKNWTAPGPDMIHAYWLKKLTALHERLAAQMNQLLRDGTHPEWLTEGRT--ILIQKDPSKGAIPSNYRPITCLSPTWKLMSGIIATKINRHMDQ--FMSNTQKGIGRDSRGAKHQLLVDRTVAQDCKSRH-TNLCTAWIDYKKAYDSMPHTWITECLELYNINRTLRAFIGNSMKLLKTTLEA-NGKPLAQV-SIKCGTYQGDALSPLLFCIGLNPLSQIITKTGYGYRLRNGANISHLLYMDDIKLYAKSERDIDSLIHTTRIYSTDIGMSFGLEKCSRMVTKRGKVVHTGGVSLPEGTIADI--EDSYKYLGIPQANGNLEQATRKAATAKYLQRVRQVLRSQLNGKNKTRAINSYALPVIRYPAG-------IIRWPKEEIQTTDVKTRKLLTMHGGFHAKS-NTLRLYASRKEGGRGLV 529
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Medaka
Match: ENSORLT00000029550.1 (pep primary_assembly:ASM223467v1:10:12459435:12462428:-1 gene:ENSORLG00000024533.1 transcript:ENSORLT00000029550.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.9518 bits (193), Expect = 1.916e-14
Identity = 83/418 (19.86%), Postives = 179/418 (42.82%), Query Frame = 2 
Query:   77 RIVGPDK------KCI--------RALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQL-HKNQETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALS-------RIKTILDSLLHPTQ-KFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLGDDS-ENIHDYFLYGSSSLGCL 1258
            + VGPD       KC+          LFN I  + K P++W+R  + L+ I   + ++ + +++R I  +    K++  ++  +L   +     +C  Q          +    + +  E     +K LH V++D+   +  +P   +WY +   G+ +K   ++++M++   T  +   G+ +   + +  G++QG  LS  LF + I+ + D V +E+           +  +D IV+ S+S+E +   L       +   +K   SK  Y  L  ++Q   V +   E+  + E   +KY G      G  D G  + + +        ++  +L     P + K   Y+  +   L++ L+  +V        ++++   +    K+L+  LG    + I + ++ G++ + C+
Sbjct:  530 KAVGPDDVPVEVWKCLGETAVEFLTRLFNRILESEKMPEEWRR--SVLVPIFKNKGDMQNCSNYRGIKLMSHTMKLWERVVEARLRKKVE----ICEQQYGFMPRKSTTDAIFALRMVMEKYREGQKELHCVFVDLEKAYDRVPREELWYCMRSSGVAEKYVRVVQDMYERSMTVVRCAVGQTEEFKVEV--GLHQGSALSPFLFAMLIDRLTDEVRQESPW--------TMMFADDIVICSESREQVEEQLERWRFALERRGMKVSRSKTEYMCLNERDQGRSVRLQGTEVKKVQE---FKYLGSTVQCDG--DCGKEVKRRVQAGWSGWRKVSGVLCDRRVPARLKGKVYKTVVRPALLYGLETVAVR-------QRQEAEMEVAEMKMLRFSLGVTRLDRIRNEYIRGTAHVACV 919
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Medaka
Match: ENSORLT00000046874.1 (pep primary_assembly:ASM223467v1:7:16581403:16583898:1 gene:ENSORLG00000023007.1 transcript:ENSORLT00000046874.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.5666 bits (192), Expect = 2.016e-14
Identity = 82/342 (23.98%), Postives = 160/342 (46.78%), Query Frame = 2 
Query:  104 IRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMII--TIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNI--LAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKVTMHDEE--IP---LINEQNFYKYFG--ENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFP 1096
            + A  N + R+   P+     +T  ILI+   ++ + P+++RPI +L   +K+   I+  K+   + +  F+   QK +G  S  A+H +++  T+A++  +R+  NL   W+D    +  +PH  I   ++   +N+  R  I    +  +T  +  NGK  + V +I  GI+QG  LS  LF + +N +   +++    Y   +  NI  L + D I L + S+  I S++++T  ++    + F   KC      + +     +H E+  +P   + + ++ YKY G  +  G   +        K L R++ +L S L+   K  A   +    + +P
Sbjct:  120 LAAQMNQLLRDGTHPEWLTEGRT--ILIQKDPSKGAVPSNYRPITRLSTTWKLMSGIIATKINRHMDQ--FMSNTQKGIGRDSRGAKHQLLVDRTVAQDCKLRH-TNLCTAWIDYKKAYDSMPHTWITECLELYNINRTLRAFIGNSMKLWKTTLEA-NGKPLAQV-SIKCGIHQGDALSPLLFCIGLNPLSRIITKTGYGYRLRNGANISHLLYMDDIKLYAKSERDIESLIHTTRIYSTDIGMSFGLEKCSRMVTKRGK----VVHTEQAIVPEGTIADIEDSYKYLGIPQANGNLEQATRKAATAKYLQRVRQVLRSQLNGKNKTRAINSYALPVIRYP 450
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Medaka
Match: ENSORLT00000033783.1 (pep primary_assembly:ASM223467v1:22:28528438:28531431:-1 gene:ENSORLG00000030281.1 transcript:ENSORLT00000033783.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.5666 bits (192), Expect = 2.086e-14
Identity = 83/418 (19.86%), Postives = 179/418 (42.82%), Query Frame = 2 
Query:   77 RIVGPDK------KCI--------RALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQL-HKNQETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALS-------RIKTIL-DSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLGDDS-ENIHDYFLYGSSSLGCL 1258
            + VGPD       KC+          LFN I  + K P++W+R  + L+ I   + +  + +++R I  +    K++  ++  +L   +     +C  Q          +    + +  E     +K LH V++D+   +  +P   +WY +   G+ +K   ++++M++   T  +   G+ +   + +  G++QG  LS  LF + ++ + D V +E+           +  +D IV+ S+S+E +   L S     +   +K   SK  Y  L  ++Q   V +   E+  + E   +KY G      G  D G  + + +        ++  +L D  +    K   Y+  +   L++ L+  +V        ++++   +    K+L+  LG    + I + ++ G++ + C+
Sbjct:  530 KAVGPDDVPVEVWKCLGETAVEFLTRLFNRILESEKMPEEWRR--SVLVPIFKNKGDTQNCSNYRGIKLMSHTMKLWERVVEARLRKKVE----ICEQQYGFMPRKSTTDAIFALRMVMEKYREGQKELHCVFVDLEKAYDRVPREELWYCMRSSGVAEKYVRVVQDMYERSMTVVRCAVGQTEEFKVEV--GLHQGSALSPFLFAMLMDRLTDEVRQESPW--------TMMFADDIVICSESREQVEEQLESWRFALERRGMKVSRSKTEYMCLNERDQGRSVRLQGAEVKKVQE---FKYLGSTVQCDG--DCGKEVKRRVQAGWSGWRKVSGVLCDRRVSARLKGKVYKTVVRPALLYGLETVAVR-------QRQEAEMEVAEMKMLRFSLGVTRLDRIRNEYIRGTAHVACV 919
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Planmine SMEST
Match: SMESG000053822.1 (SMESG000053822.1)

HSP 1 Score: 506.523 bits (1303), Expect = 1.330e-154
Identity = 289/733 (39.43%), Postives = 442/733 (60.30%), Query Frame = 2 
Query:   59 LTIADWRIVGPDKKCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQET--KVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCD-------RKEQLGYDQKLSKLLKSFLGDDSENIHDYFLYGSSSLGCLGIVPSIDEYCIQSIIHLLRMLNTNDNKLRKFFEKELFDIIGNNGEDSSISKALEWINNESGSDREEAHGNMFVKYRYSVRAIRDKFNIIIKLKNENEKYIIEIKFLDSKCHLNCEKLKDKFTIIHEMIGLIYTQKWLQLENPVKIARPAGIIWVTSYLINTIELDDANYFFLINARNNVLDLNYSPSRLKKGLNVDCRLCKMEYETQKHIFNNCIEGIITRENAFNNVRKTVSDYFLNKGFNFYVKKA--FPGVGAISQPDLIIIKSNRNETLNILIINVQYDSNQHFERIRDENYQKYKDVVAELEKRNNCKTTLALLVVGAL 2224
            +T+ADW+I+ P    I A+ NN+ RN   PK+WK F+T LIL  GK++E    +SWRP+  +D  Y+IF  +LN +LL WI KG  +  NQKA+GI  GCAEH+  + +A +++ R KK LH+VWLDI + F  LPH++IWYT++ MG+ K+T  LIKE+++ + T++  +    +S  +NI +G+ QGCPLS+TLF LSI+YIL  V  +   ++HD N++ILA++D IVL+SDS   I   L  T+  A  A+L+F PSK GY  ++ N     K+ +++EE+P+I+ +N YKY G +F +K   D+   +  AL+   T+  S LHP QK +AY+ FIH +LIF  +N  +   I +CD       R++QLGYDQK+  LLK+ +GD    +++YFLY    LG LG+  SIDEY IQS+  + R+ ++ +   R+  +KEL    G    + +   AL+WIN E   D+   + + FVK++ SV A++ KF I IKLK E+  + +E+++ +   ++    L      +H+ +GL Y +KW ++     I    G      YL  +  L+DA Y FLI ARNN+L+LNY+  RLK  L+  CRLC ++ ETQ H  ++C+   I                    GF   V+K+  +  V    +PD+ +I+SNRN+ +++L + V YDS + FE+ R++NY KYKD+  E+ K    K T++ +V+G L
Sbjct:  269 ITVADWKIISPKHILITAICNNVLRNGVCPKKWKLFRTVLILKPGKKDESFKTSSWRPLAIMDTAYRIFATLLNNRLLAWIKKGNLISQNQKAIGIPDGCAEHSATLHLAIDHARRMKKELHVVWLDITDAFGSLPHDLIWYTLEGMGMKKETVCLIKELYRDISTFFDCQGMISES--VNITKGVKQGCPLSMTLFCLSIDYILKSVLIDCPFHLHDMNISILAYADDIVLVSDSFTKIEMALRMTVRLASHANLRFKPSKSGYLSINNNNHDIYKLYLYNEEVPIISNENKYKYLGIDFSHKQYQDIDGRLQSALALTNTLFKSYLHPAQKLNAYKTFIHSKLIFSFRNCIIGHRILDCDRNRITQGREKQLGYDQKVKALLKTMVGDKFHALNNYFLYTHCKLGGLGVSSSIDEYLIQSVTGITRLFHSYNTDFREMMKKELAHARG----EENFEAALKWINCE--IDKPFKNTSFFVKFQKSVYALKRKFEIYIKLKFEDNSFKLEMRYKNRISYIGYRNLGTLSKDLHDFVGLHYAEKWYEMRVQGHIGNAIGDSITAKYLTASDILNDAQYCFLIKARNNLLNLNYNAYRLKFSLDTMCRLCHLDAETQAH--HSCLPREI--------------------GFEIDVEKSPKYISVPTKLKPDM-VIRSNRNKEIHVLDLKVPYDSVEGFEKAREDNYVKYKDLAIEIGKAFGEKATISAVVIGCL 970
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Planmine SMEST
Match: SMESG000053822.1 (SMESG000053822.1)

HSP 1 Score: 506.138 bits (1302), Expect = 2.095e-154
Identity = 290/737 (39.35%), Postives = 443/737 (60.11%), Query Frame = 2 
Query:   59 LTIADWRIVGPDKKCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQET--KVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCD-------RKEQLGYDQKLSKLLKSFLGDDSENIHDYFLYGSSSLGCLGIVPSIDEYCIQSIIHLLRMLNTNDNKLRKFFEKELFDIIGNNGEDSSISKALEWINNESGSDREEAHGNMFVKYRYSVRAIRDKFNIIIKLKNENEKYIIEIKFLDSKCHLNCEKLKDKFTIIHEMIGLIYTQKWLQLENPVKIARPAGIIWVTSYLINTIELDDANYFFLINARNNVLDLNYSPSRLKKGLNVDCRLCKMEYETQKHIFNNCIEGIITRENAFNNVRKTVSDYFLNKGFNFYVKKA--FPGVGAISQPDLIIIKSNRNETLNILIINVQYDSNQHFERIRDENYQKYKDVVAELEKRNNCKTTLALLVVGALGSWD 2236
            +T+ADW+I+ P    I A+ NN+ RN   PK+WK F+T LIL  GK++E    +SWRP+  +D  Y+IF  +LN +LL WI KG  +  NQKA+GI  GCAEH+  + +A +++ R KK LH+VWLDI + F  LPH++IWYT++ MG+ K+T  LIKE+++ + T++  +    +S  +NI +G+ QGCPLS+TLF LSI+YIL  V  +   ++HD N++ILA++D IVL+SDS   I   L  T+  A  A+L+F PSK GY  ++ N     K+ +++EE+P+I+ +N YKY G +F +K   D+   +  AL+   T+  S LHP QK +AY+ FIH +LIF  +N  +   I +CD       R++QLGYDQK+  LLK+ +GD    +++YFLY    LG LG+  SIDEY IQS+  + R+ ++ +   R+  +KEL    G    + +   AL+WIN E   D+   + + FVK++ SV A++ KF I IKLK E+  + +E+++ +   ++    L      +H+ +GL Y +KW ++     I    G      YL  +  L+DA Y FLI ARNN+L+LNY+  RLK  L+  CRLC ++ ETQ H  ++C+   I                    GF   V+K+  +  V    +PD+ +I+SNRN+ +++L + V YDS + FE+ R++NY KYKD+  E+ K    K T++ +V+G L   D
Sbjct:  269 ITVADWKIISPKHILITAICNNVLRNGVCPKKWKLFRTVLILKPGKKDESFKTSSWRPLAIMDTAYRIFATLLNNRLLAWIKKGNLISQNQKAIGIPDGCAEHSATLHLAIDHARRMKKELHVVWLDITDAFGSLPHDLIWYTLEGMGMKKETVCLIKELYRDISTFFDCQGMISES--VNITKGVKQGCPLSMTLFCLSIDYILKSVLIDCPFHLHDMNISILAYADDIVLVSDSFTKIEMALRMTVRLASHANLRFKPSKSGYLSINNNNHDIYKLYLYNEEVPIISNENKYKYLGIDFSHKQYQDIDGRLQSALALTNTLFKSYLHPAQKLNAYKTFIHSKLIFSFRNCIIGHRILDCDRNRITQGREKQLGYDQKVKALLKTMVGDKFHALNNYFLYTHCKLGGLGVSSSIDEYLIQSVTGITRLFHSYNTDFREMMKKELAHARG----EENFEAALKWINCE--IDKPFKNTSFFVKFQKSVYALKRKFEIYIKLKFEDNSFKLEMRYKNRISYIGYRNLGTLSKDLHDFVGLHYAEKWYEMRVQGHIGNAIGDSITAKYLTASDILNDAQYCFLIKARNNLLNLNYNAYRLKFSLDTMCRLCHLDAETQAH--HSCLPREI--------------------GFEIDVEKSPKYISVPTKLKPDM-VIRSNRNKEIHVLDLKVPYDSVEGFEKAREDNYVKYKDLAIEIGKAFGEKATISAVVIGCLDEPD 974
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Planmine SMEST
Match: SMESG000074876.1 (SMESG000074876.1)

HSP 1 Score: 405.986 bits (1042), Expect = 8.072e-125
Identity = 262/787 (33.29%), Postives = 425/787 (54.00%), Query Frame = 2 
Query:   68 ADWRIVGPDKKCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKN---------LHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSREN-QLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQ-------LGYDQKLSKLLKSFLGDDSENIHDYFLYGSSSLGCLGIVPSIDEYCIQSIIHLLRMLNTNDNKLRKFFEKELFDIIG--NNGEDSSISKALEWINNESGSDREEAHGNMFVKYRYSVRAIRDKFNIIIKLK-NEN--EKYIIEIKFLDSKCHLNCEKLKDKFTIIHEMIGLIYTQKWLQLENPVKIARPAGIIWVTSYLINTIELDDANYFFLINARNNVLDLNYSPSRLKKGLNVDCRLCKMEYETQKHIFNNC-IEGIITRENAFNNVRKTVSDYFLNKGFNFYVKKAFPGVGAISQ-PDLIIIKSNRNETLNILIINVQYDSNQHFERIRDENYQKYKDVVAELEKRNNCKTTLALLVVGALGSWDSDNDNVLKVMGLTDSEIRELIELSTMAAVNASYNIYMNHL 2356
            +DWR + P+ + +   FN I      P+QW+ FKT LI+   K +  +D +S+RPI  LD  Y+IF  +LN +LLGWI  G  L  +QK +    GC+EHN IIT  +E +  N+KN         LH+ +LD+ + F  LPH ++W+T+ K+GLN  T  L K ++   ++ +  ++   K   I + +G+ QGCPLS+TLF LSI++I   + + N    + + N+N LA++D IVL+++S + I ++L      A    L+F  +KCGYY    NQ   + + ++ IP I   + Y Y G  FG   + ++  ++   LS    I  S+L P QK  A + F+   L F L+N  ++    +     Q       +GYD+K+   LKS     S  +++ FLY  ++LG LGI  + ++Y +Q+++H   +  + D  ++    +EL   +   N G + +   AL+WIN   GS  E      F K R S+R ++ K NIIIK K NEN  E  I      ++K   N E   D    +HE+IG+I+  KW   ++  ++A+      +++ LI   +++D+++ F I ARNN+L LNYS  R  K L++ CR CK E E+Q HI  +C  +G I R N   N+   ++   ++      +    P +  I++ PDLII + N ++ ++++ I   YD  ++F+  R+ N +KY  +  +L        TL  +VVGALGSWD  N++VLK++GL+  +I+     S   A+ AS+N+Y  H+
Sbjct:  321 SDWREIDPEFEFLTFFFNYIIEIGLIPEQWRTFKTLLIIKPNKAHLANDISSYRPIAILDTSYRIFTKVLNRRLLGWIKNGNLLSKSQKGIIHPDGCSEHNFIITSLREMT--NRKNYKKKSKLAELHLCYLDLADAFGSLPHELLWFTLKKLGLNTSTLTLFKNLYTDCKSVFICDHMNSKP--IKVTKGVKQGCPLSMTLFCLSIDFIFKRIEKLNPDFTLQNINLNSLAYADDIVLIANSFDNIENLLREVYSLASKVGLEFRANKCGYYSSKLNQNYALKIGNDSIPNIANNDTYDYLGVPFGESKRQNIEKVIALNLSYFNKINKSILSPPQKIKALKLFLQSRLPFHLRNRVIDIQTLSSPHGRQGTNLERDIGYDEKIRHGLKSLFNIPSSLLNNSFLYAHTALGGLGITCANEDYMVQNVVHAFHLFTSKDTNIKHISIEELKSTVKSRNGGINPTERVALDWIN--GGSFNEGHVATWFTKVRKSIRDLKSKLNIIIKFKINENQVEMQIEAPSLQNNKAFFNYENKLDICHYLHELIGIIHFHKWNNCKSQGRLAQCISQSKLSNKLIIDGKMNDSDWLFAIKARNNILQLNYSAYRSLKNLDLKCRKCKAERESQAHILCHCNKDGRIKRHNRIQNL---LAKILIDNNLVVDIDTK-PFLTEINERPDLIITR-NADKKIHLVDIKSPYDLVKNFDEARNNNLKKYAAIRNDLGSNTGFDVTLDTIVVGALGSWDPRNEDVLKMLGLSQDKIKCFAIDSCREAIKASHNMYKLHI 1096
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Planmine SMEST
Match: SMESG000068632.1 (SMESG000068632.1)

HSP 1 Score: 332.413 bits (851), Expect = 3.029e-97
Identity = 165/425 (38.82%), Postives = 265/425 (62.35%), Query Frame = 2 
Query:  221 SWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNCD-------RKEQLGYDQKLSKLLKSFLGDDSENIHDYFLYGSSSLGCLGIVPSIDEYCIQSIIHLLRMLNTNDNKLRKFFEKELFDIIGN-------NGEDSSISKALEWINNESGSDRE 1453
            SWRP+  ++  Y+IF  +LN ++L WI+ G  L  NQKA+G + GCAEH   I + ++YSIRN K LHI+WLDI + F  +PH++IW+T+ +MGL+K T  L+K+M+ G+ T++  E   E S+ I + +G+ QGCPLS+TLF ++I++I+  V  ++  + + HN++ILA++D +VL++DS   I  IL++T+E A   +LKF PSK GY     N   + ++++E IP +N  N Y+Y G +F +  K+++ + ++      K I DS LHP+QK ++Y+ FIH  LIF L+N ++N ++ +C        R+ QLG+DQK+  ++K  +GD    I+D F+Y    L  LG   SIDEY IQS++H L M+++ D      +  EL D  GN       + E SSI+ + + ++     +R+
Sbjct:  658 SWRPLAIMNTSYRIFATLLNDRILNWISSGNLLYKNQKAIGASDGCAEHQTTINLIRDYSIRNNKQLHIIWLDIADAFGSIPHDLIWHTLTEMGLSKNTISLLKDMYTGINTFFDCEG--ETSDRIPLTKGVKQGCPLSMTLFCITIDFIIKTVLEKHPFFFNGHNISILAYADDLVLIADSHTSILDILHTTVECATYMNLKFKPSKSGYMDT-SNANRQTSLYNETIPTVNNDNLYRYLGVDFSFSKKHNIDSRLNICTHDTKLIFDSYLHPSQKIYSYKTFIHSRLIFTLRNCNINHMVLDCHSKLKTKGRESQLGFDQKIKNIIKPMIGDFFHQINDNFIYADCKLVELGFTSSIDEYIIQSVVHTLYMISSKDELFSNMYISELKDARGNGDILRSLSNEISSITHSTKELDKAQAVNRD 1079
[Close]
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Planmine SMEST
Match: SMESG000076041.1 (SMESG000076041.1)

HSP 1 Score: 325.479 bits (833), Expect = 2.526e-95
Identity = 156/387 (40.31%), Postives = 249/387 (64.34%), Query Frame = 2 
Query:   56 KLTIADWRIVGPDKKCIRALFNNIFRNRKFPKQWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWITKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNFFIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVINIFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIVLMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKVTMHDEEIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQKFHAYRKFIHLELIFPLQNSSVNPVIFNC--------DRKEQLGYDQKLSKLLKSF 1192
            K++ +DWRI+ PD     ++ N+I R  + P+ WK F+TKLIL  GK ++    +SWRP+  ++  Y+IF  +LN ++L WI+ G  L  NQKA+G + GCAEH+  I + ++YSIRN K LH++WLDI + F  +PHN+IW+T+ ++GL+K T  L+K+M+ G+ T++  E   E S++I + +G+ QGCPLS+TLF ++I++I+  V  ++  + + HN++ILA++D  VL++DS   I  IL++T+E A   +LKF PSK GY     N   + ++++E IP +N  N Y Y G +F +  K+++   ++      K I DS LHP+Q  ++Y+ FIH  LIF L+N +VN ++ +C         R  QLGYDQK+ K  K++
Sbjct:  698 KISFSDWRIISPDFLFPTSMCNSILRTLRCPEDWKTFRTKLILKTGKSDKSFIASSWRPLAIMNTSYRIFATLLNDRILNWISSGNLLSKNQKAIGASDGCAEHHTTIHLVRDYSIRNNKQLHVIWLDIADAFGSIPHNLIWHTLTEIGLSKNTITLLKDMYTGINTFFDCEG--ETSDLIPLTKGVKQGCPLSMTLFCITIDFIIKTVLEKHPFFFNGHNISILAYADDSVLIADSHASILDILHTTVECATSMNLKFKPSKSGYMDT-SNANRQTSLYNETIPTVNNDNLYSYLGVDFSFSKKHNIDARLNICTHDTKLIFDSYLHPSQNIYSYKTFIHSRLIFTLRNCNVNHMVLDCHTKTKKVNGRMNQLGYDQKIKKPFKTY 1081
The following BLAST results are available for this feature:
BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CU462878.31.388e-824.64pep chromosome:GRCz11:17:8542203:8545189:1 gene:EN... [more]
CABZ01033394.15.888e-721.83pep chromosome:GRCz11:13:6032844:6038477:-1 gene:E... [more]
CT956002.29.014e-726.05pep chromosome:GRCz11:4:64279882:64284924:-1 gene:... [more]
si:dkeyp-88h4.23.350e-622.89si:dkeyp-88h4.2 [Source:ZFIN;Acc:ZDB-GENE-131121-1... [more]
CU024870.24.796e-622.89pep chromosome:GRCz11:25:23489979:23495448:1 gene:... [more]
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bmi13.390e-825.45BMI1 proto-oncogene, polycomb ring finger [Source:... [more]
ENSXETT00000039541.19.727e-825.41pep primary_assembly:Xenopus_tropicalis_v9.1:1:487... [more]
ENSXETT00000025099.12.364e-725.11pep primary_assembly:Xenopus_tropicalis_v9.1:KV461... [more]
ENSXETT00000032317.15.574e-723.79pep primary_assembly:Xenopus_tropicalis_v9.1:1:130... [more]
ENSXETT00000036577.16.887e-720.25pep primary_assembly:Xenopus_tropicalis_v9.1:KV460... [more]
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|P16423|POLR_DROME6.574e-1823.33Retrovirus-related Pol polyprotein from type-2 ret... [more]
sp|Q03278|PO21_NASVI8.949e-1724.08Retrovirus-related Pol polyprotein from type-1 ret... [more]
sp|Q03279|PO21_BRACO2.939e-1122.92Retrovirus-related Pol polyprotein from type-1 ret... [more]
sp|Q03274|PO22_POPJA1.659e-923.21Retrovirus-related Pol polyprotein from type-1 ret... [more]
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A131XRS21.089e-5324.62Putative reverse transcriptase (Fragment) OS=Ixode... [more]
A0A2G5S9Z31.873e-4924.84Reverse transcriptase domain-containing protein OS... [more]
A0A2G5SAA73.178e-4924.71Reverse transcriptase domain-containing protein OS... [more]
A0A4D5S5F82.709e-4824.01Putative reverse transcriptase (Fragment) OS=Ixode... [more]
A0A4Y2UBZ61.164e-4726.21Retrovirus-related Pol polyprotein from type-1 ret... [more]
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000031340.13.570e-1626.42pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000033573.12.784e-1522.41pep primary_assembly:Astyanax_mexicanus-2.0:3:3140... [more]
ENSAMXT00000034831.13.096e-1322.37pep primary_assembly:Astyanax_mexicanus-2.0:3:1621... [more]
ENSAMXT00000055550.11.117e-1221.79pep primary_assembly:Astyanax_mexicanus-2.0:1:1655... [more]
ENSAMXT00000029797.12.660e-1121.10pep primary_assembly:Astyanax_mexicanus-2.0:20:119... [more]
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000037842.11.305e-1419.86pep primary_assembly:ASM223467v1:6:23612405:236156... [more]
ENSORLT00000043092.11.628e-1424.11pep primary_assembly:ASM223467v1:4:30731179:307340... [more]
ENSORLT00000029550.11.916e-1419.86pep primary_assembly:ASM223467v1:10:12459435:12462... [more]
ENSORLT00000046874.12.016e-1423.98pep primary_assembly:ASM223467v1:7:16581403:165838... [more]
ENSORLT00000033783.12.086e-1419.86pep primary_assembly:ASM223467v1:22:28528438:28531... [more]
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BLAST of Retrovirus-related Pol polyprotein LINE-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053822.11.330e-15439.43SMESG000053822.1[more]
SMESG000053822.12.095e-15439.35SMESG000053822.1[more]
SMESG000074876.18.072e-12533.29SMESG000074876.1[more]
SMESG000068632.13.029e-9738.82SMESG000068632.1[more]
SMESG000076041.12.526e-9540.31SMESG000076041.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008223 ID=SMED30008223|Name=Retrovirus-related Pol polyprotein LINE-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2854bp
TATGGAGGATGAAAGTGATGATATAGAGGATGAAAGTGATGAAGAAGAGG
ATGGCAAATTGACCATTGCAGATTGGCGGATAGTAGGCCCAGATAAAAAA
TGCATTCGGGCTTTATTCAACAATATTTTTCGAAATAGAAAATTTCCGAA
ACAATGGAAGAGATTCAAAACTAAACTTATACTTATTAAAGGAAAAGAAA
ATGAATTAAGTGATCCAACATCATGGAGACCTATTCCAAAATTGGATCCA
TTATACAAGATTTTTCTTGCCATTCTAAATTATAAATTGCTTGGTTGGAT
CACAAAAGGTGGATTTTTGTGTGCCAATCAAAAAGCCGTAGGGATAACGA
GTGGATGTGCTGAGCACAATATGATTATTACTATTGCGAAGGAATATTCT
ATTAGAAACAAGAAAAACCTTCACATTGTTTGGTTAGATATTAATAATTT
CTTTATCGATTTACCACATAATGTGATTTGGTATACTGTGGATAAAATGG
GACTTAATAAAAAGACACGTGAGCTGATTAAGGAAATGCACCAAGGTGTC
AGAACATATTATCAATTCGAAAACGGCAAAGAAAAATCGAATGTAATAAA
TATTTTCCGAGGGATAAATCAAGGATGTCCATTGTCCATAACTCTTTTCA
GATTATCAATCAACTATATATTAGATTATGTCAGCCGGGAAAATCAGTTG
TATATCCATGACCATAATGTGAACATTCTGGCTCATTCAGATTGCATAGT
GCTGATGTCTGATTCCAAAGAAGGAATAACCAGTATTCTGAATAGCACTA
TAGAATTTGCTGACATGGCAGACTTAAAGTTTATTCCATCAAAATGTGGG
TATTATCAATTGCATAAGAATCAGGAAACAAAAGTAACAATGCATGACGA
AGAAATACCTCTGATTAATGAGCAAAACTTTTATAAGTATTTTGGAGAGA
ATTTCGGATACAAAGGCAAATATGATATGGGTAACCTAATGGACAAGGCT
CTATCGAGAATAAAAACGATATTGGATTCACTGCTGCATCCAACTCAAAA
ATTTCATGCGTATAGAAAATTTATACACTTAGAATTAATTTTCCCGCTTC
AAAATTCTTCAGTGAATCCCGTGATATTCAATTGCGATCGAAAAGAGCAG
TTGGGGTACGACCAGAAACTTTCAAAACTGCTTAAAAGCTTCCTAGGAGA
TGATAGTGAAAATATCCATGACTATTTTCTGTATGGATCATCGAGCCTCG
GATGTTTGGGGATTGTACCTAGCATTGATGAATATTGCATTCAAAGCATT
ATACACCTTCTGCGTATGCTCAATACAAATGATAACAAGCTGAGGAAATT
CTTTGAGAAAGAGCTATTTGATATTATTGGGAATAATGGTGAGGATTCCA
GCATAAGTAAAGCACTTGAATGGATTAATAATGAATCAGGATCAGATAGA
GAAGAGGCCCATGGCAACATGTTTGTGAAATACCGTTATTCAGTGCGTGC
AATTCGAGATAAATTCAACATCATAATTAAACTGAAGAATGAGAATGAGA
AATATATCATAGAAATCAAGTTTCTCGATAGTAAATGTCACTTAAACTGT
GAAAAATTGAAAGACAAGTTTACAATTATTCATGAAATGATTGGTTTGAT
ATATACCCAAAAATGGCTTCAGTTAGAAAATCCGGTTAAGATTGCCCGAC
CGGCCGGAATCATTTGGGTTACATCATATCTTATCAATACCATTGAGCTT
GATGATGCAAATTATTTTTTCCTTATCAATGCAAGGAACAATGTGCTGGA
TCTCAATTATTCACCTTCTAGGTTGAAGAAAGGTTTGAATGTCGACTGTA
GGTTGTGCAAAATGGAGTACGAAACACAAAAGCACATATTTAACAACTGT
ATTGAAGGAATCATAACTAGAGAAAACGCGTTTAATAACGTCCGGAAAAC
TGTTTCCGATTATTTCCTTAACAAGGGATTTAATTTTTATGTTAAGAAAG
CGTTTCCAGGCGTAGGGGCTATCTCACAACCAGACCTCATCATCATTAAA
TCAAATCGTAATGAAACATTGAATATACTCATTATTAACGTGCAATATGA
TAGTAATCAACATTTTGAAAGGATCCGAGATGAGAATTATCAGAAATATA
AAGATGTAGTTGCGGAATTAGAAAAGAGAAATAATTGCAAGACGACATTA
GCATTGCTTGTTGTAGGAGCATTGGGATCATGGGATTCTGACAATGACAA
TGTCTTGAAAGTAATGGGATTGACTGACAGTGAGATCAGAGAGCTAATAG
AACTTTCAACCATGGCTGCTGTTAATGCAAGCTACAACATTTATATGAAC
CATTTACATAGCCGTCCTTCATAAACATTTCTAGTGCCTTGCTCTCTTTT
AGTCTAGATGTTAGATTTATTGCTATCGGTTTGGTTTGTTGATAAAATAT
GTTTTAAATATATTTTTTCTGAATTTGTTTTTTGTCTATTTTATACTTGT
TTTAGTAGGCAGCAAGAAGTTGTATGGAGTAGTAACTTTTGTTTAAGGGA
GTACCTATTTCTTTATTCTGTTATCAGCCTTAGGTTTAATAATATTCCGC
TAGTATCACCATTTCAATCTCTGTCTACAAGACCGAGCAATAGTGAAACT
ATTGAAACTAAGATTAACTACAACTGGTTTTATTAATATATTCTCTGAGT
ACGATTTTCGACAGGGTTAAAAATTAGTTTGGTAGGTGATCTCTTTATTT
TTGCATTTTCTTATACAGGTTACTCCTGAATTTTCAATGAGTAAAATTTG
TCAAACCTTTTAAATTTGAAAGCTTCCATCTCGTAATCCCTTATTTGCTT
AAGG
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protein sequence of SMED30008223-orf-1

>SMED30008223-orf-1 ID=SMED30008223-orf-1|Name=SMED30008223-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=791bp
MEDESDDIEDESDEEEDGKLTIADWRIVGPDKKCIRALFNNIFRNRKFPK
QWKRFKTKLILIKGKENELSDPTSWRPIPKLDPLYKIFLAILNYKLLGWI
TKGGFLCANQKAVGITSGCAEHNMIITIAKEYSIRNKKNLHIVWLDINNF
FIDLPHNVIWYTVDKMGLNKKTRELIKEMHQGVRTYYQFENGKEKSNVIN
IFRGINQGCPLSITLFRLSINYILDYVSRENQLYIHDHNVNILAHSDCIV
LMSDSKEGITSILNSTIEFADMADLKFIPSKCGYYQLHKNQETKVTMHDE
EIPLINEQNFYKYFGENFGYKGKYDMGNLMDKALSRIKTILDSLLHPTQK
FHAYRKFIHLELIFPLQNSSVNPVIFNCDRKEQLGYDQKLSKLLKSFLGD
DSENIHDYFLYGSSSLGCLGIVPSIDEYCIQSIIHLLRMLNTNDNKLRKF
FEKELFDIIGNNGEDSSISKALEWINNESGSDREEAHGNMFVKYRYSVRA
IRDKFNIIIKLKNENEKYIIEIKFLDSKCHLNCEKLKDKFTIIHEMIGLI
YTQKWLQLENPVKIARPAGIIWVTSYLINTIELDDANYFFLINARNNVLD
LNYSPSRLKKGLNVDCRLCKMEYETQKHIFNNCIEGIITRENAFNNVRKT
VSDYFLNKGFNFYVKKAFPGVGAISQPDLIIIKSNRNETLNILIINVQYD
SNQHFERIRDENYQKYKDVVAELEKRNNCKTTLALLVVGALGSWDSDNDN
VLKVMGLTDSEIRELIELSTMAAVNASYNIYMNHLHSRPS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0022857transmembrane transporter activity
GO:0003964RNA-directed DNA polymerase activity
GO:0004518nuclease activity
GO:0004519endonuclease activity
GO:0016740transferase activity
GO:0016779nucleotidyltransferase activity
GO:0016787hydrolase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0055085transmembrane transport
GO:1902600hydrogen ion transmembrane transport
GO:0006278RNA-dependent DNA biosynthetic process
GO:0090305nucleic acid phosphodiester bond hydrolysis
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR000477RT_dom
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 508..528
NoneNo IPR availablePANTHERPTHR19446REVERSE TRANSCRIPTASEScoord: 35..299
NoneNo IPR availablePANTHERPTHR19446:SF427coord: 35..299
IPR000477Reverse transcriptase domainPFAMPF00078RVT_1coord: 67..288
e-value: 1.2E-19
score: 70.7
IPR000477Reverse transcriptase domainPROSITEPS50878RT_POLcoord: 43..318
score: 11.786