TNF receptor-associated factor
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008172 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF6 (TNF receptor associated factor 6 [Source:HGNC Symbol;Acc:HGNC:12036]) HSP 1 Score: 105.531 bits (262), Expect = 2.823e-24 Identity = 95/351 (27.07%), Postives = 154/351 (43.87%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLL---------------VSKIPYIQSSIHDLKEDLENNKNIITELFS-----------ISKSIQELIMKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHLGIWIVE 2259
+C +C LR A QT CG R C CI + + KCP DN +LL EN+LF D REI L V CP + C + +L+ + H CE+ ++DC +C++ H H + C R V+C+ C S+ + IH P +C+ N ++ + L+C C F+ C+ +K+ + +L H +N H +L +S++ Q +IH L+ L + I EL + + ++I+ L K I A++C +G +IWKI NF + + + I S FY+ + GY C +HL + +
Sbjct: 69 ECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCP-VDNEILL-ENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDK-EIHDQNCPLANVICE------YCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCH--EKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQC------NGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKL-CMRLHLQLPTAQ 401 HSP 2 Score: 28.4906 bits (62), Expect = 2.823e-24 Identity = 10/32 (31.25%), Postives = 19/32 (59.38%), Query Frame = 3
Query: 2259 GSHLSVSFEIINGDYDQILSWPFKHNIQIGIF 2354
+++S+ + G+YD L WPF+ I++ I
Sbjct: 404 ANYISLFVHTMQGEYDSHLPWPFQGTIRLTIL 435
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF6 (TNF receptor associated factor 6 [Source:HGNC Symbol;Acc:HGNC:12036]) HSP 1 Score: 105.531 bits (262), Expect = 2.823e-24 Identity = 95/351 (27.07%), Postives = 154/351 (43.87%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLL---------------VSKIPYIQSSIHDLKEDLENNKNIITELFS-----------ISKSIQELIMKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHLGIWIVE 2259
+C +C LR A QT CG R C CI + + KCP DN +LL EN+LF D REI L V CP + C + +L+ + H CE+ ++DC +C++ H H + C R V+C+ C S+ + IH P +C+ N ++ + L+C C F+ C+ +K+ + +L H +N H +L +S++ Q +IH L+ L + I EL + + ++I+ L K I A++C +G +IWKI NF + + + I S FY+ + GY C +HL + +
Sbjct: 69 ECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCP-VDNEILL-ENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDK-EIHDQNCPLANVICE------YCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCH--EKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQC------NGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKL-CMRLHLQLPTAQ 401 HSP 2 Score: 28.4906 bits (62), Expect = 2.823e-24 Identity = 10/32 (31.25%), Postives = 19/32 (59.38%), Query Frame = 3
Query: 2259 GSHLSVSFEIINGDYDQILSWPFKHNIQIGIF 2354
+++S+ + G+YD L WPF+ I++ I
Sbjct: 404 ANYISLFVHTMQGEYDSHLPWPFQGTIRLTIL 435
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF2 (TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032]) HSP 1 Score: 75.485 bits (184), Expect = 2.938e-19 Identity = 79/363 (21.76%), Postives = 144/363 (39.67%), Query Frame = 1
Query: 1294 CKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSC-------DNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSI-GVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDY-VSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKI----PYIQSSIHDLKEDLE----------NNKNII-------------------------TELFSISKSIQEL----IMKKFSIN--AEKCLQNEFRS--GNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
C C VLR Q +CG R C C+ L++G + C +C + +L + F D A RE+ L VCP D C ++ L+ H C + +C CK + ++ H + C R ++C +C+ ++ H E+C + ++ + + + H+ C + C F+ I C ++ + E H + H +L+S + P + H E L+ +NI+ ++ ++S +Q+L +K ++ +K L+ E + G FIWKI +F + + +IFS +FY+ +GY
Sbjct: 34 CSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHH------EVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGC--LETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGY 388 HSP 2 Score: 41.2022 bits (95), Expect = 2.938e-19 Identity = 29/110 (26.36%), Postives = 50/110 (45.45%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTELHSFIFK---------DKSIYLKLIVN 2516
++ ++IY G RG+HLS+ F ++ G D +L WPF + + + + RE P++ S + V N S L + K D +I++K IV+
Sbjct: 389 KMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNRE-HVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF4 (TNF receptor associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034]) HSP 1 Score: 72.7886 bits (177), Expect = 1.187e-16 Identity = 84/358 (23.46%), Postives = 151/358 (42.18%), Query Frame = 1
Query: 1261 FEFTNAPDR-CKCKLCFKVLRNAKQ-TECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVC--PLDLCQFRSKLQSIGVHMNSCEYRVIDC-RKCKQKITAIHEQDHNINLCEMRIVTCEYC-----------------QRSIKLN-----EMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLV----------SKIPYIQSSIHDLKEDLENNKNIITELFSISKS-IQELI--MKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
++F P R C LC K +R Q + CG R C C+QE+L+ G KCP ++ + L+ K++ D ++ L + C + C++ L+ + H+N+C + VI C +C K++ H + C R + CE+C Q S+ M+ L C C + I+ H +C CP NQ T+ ++E+L H + NT LV + P + + H ++E ++ + ++ L S + +QEL +++ S+ ++ G IWKI ++ + + + K FS +FY+ ++GY
Sbjct: 6 YKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCP--EDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACP-NQCGVGTV---AREDLPGHLKDS---CNTALVLCPFKDSGCKHRCPKLAMARH-VEESVKPHLAMMCALVSRQRQELQELRRELEELSVGSD---------GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGY 344 HSP 2 Score: 35.4242 bits (80), Expect = 1.187e-16 Identity = 15/61 (24.59%), Postives = 30/61 (49.18%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIA 2396
+LQ+ + G G+HLS+ ++ G +D +L WPF + + + L++ Q +
Sbjct: 345 KLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVT 405
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF4 (TNF receptor associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034]) HSP 1 Score: 72.7886 bits (177), Expect = 3.833e-16 Identity = 84/358 (23.46%), Postives = 151/358 (42.18%), Query Frame = 1
Query: 1261 FEFTNAPDR-CKCKLCFKVLRNAKQ-TECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVC--PLDLCQFRSKLQSIGVHMNSCEYRVIDC-RKCKQKITAIHEQDHNINLCEMRIVTCEYC-----------------QRSIKLN-----EMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLV----------SKIPYIQSSIHDLKEDLENNKNIITELFSISKS-IQELI--MKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
++F P R C LC K +R Q + CG R C C+QE+L+ G KCP ++ + L+ K++ D ++ L + C + C++ L+ + H+N+C + VI C +C K++ H + C R + CE+C Q S+ M+ L C C + I+ H +C CP NQ T+ ++E+L H + NT LV + P + + H ++E ++ + ++ L S + +QEL +++ S+ ++ G IWKI ++ + + + K FS +FY+ ++GY
Sbjct: 6 YKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCP--EDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACP-NQCGVGTV---AREDLPGHLKDS---CNTALVLCPFKDSGCKHRCPKLAMARH-VEESVKPHLAMMCALVSRQRQELQELRRELEELSVGSD---------GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGY 344 HSP 2 Score: 33.4982 bits (75), Expect = 3.833e-16 Identity = 20/79 (25.32%), Postives = 34/79 (43.04%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDS----PHENQFVGI 2438
+LQ+ + G G+HLS+ ++ G +D +L WPF R R + E+ + P ++ VGI
Sbjct: 345 KLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRGLSPFLGRADMPWCRSHSTRTEVPAQVLCPKSHKGVGI 423
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80]) HSP 1 Score: 65.0846 bits (157), Expect = 8.205e-16 Identity = 69/327 (21.10%), Postives = 130/327 (39.76%), Query Frame = 1
Query: 1279 PDRCKCKLCFKVLRNAKQTECGCRVCGQCIQ-EYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDL--CQFRSKLQSIGVHMNSCEYR-VIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYV--SXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQELIMKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYN---CKCKF 2232
P C C +C + LR+ + C C QC + E G C +C ++ D+A ++I L VVC + C + +L ++ H++ C ++ + C KC ++ + H CE+ C +C ++I+ ++ + + C + + ++ I+ H C N CPF C KE++ H + + H L +I ++ + ++ D+ + + T + S +++ E+ + IWKI+ + + K +IFS F S FGY C C F
Sbjct: 13 PADCTCPICEQALRDPIKLNCDHHYCRQCFENENRTPG---CAAC--QTIIQPELCQHDRAKQKQILALPVVCTFESSGCPWDGQLGTLHDHLSECTFKSSLKCEKCGRQFAKNDLEKHRAK-CELNRAVCSFCNKTIRDSD------RERHPKTCPQVIISCPFQCGLTDRPRLEIEAHCPSCPNVDNVCPFVPYGCTFAG--GKESIQQHLSDEPVRHLMYLCDEITDLKGTYELMERDMGSFNDRQTRILSAAETCTEMFGPQ-----------------LIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLF 308 HSP 2 Score: 38.891 bits (89), Expect = 8.205e-16 Identity = 28/107 (26.17%), Postives = 47/107 (43.93%), Query Frame = 3
Query: 2238 FGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQ---TIAPEIDSPHE----------NQFVGIQNFLSFTELHSFIFKDKSIYLKLIVNK 2519
FG G +S+ ++ G++D L WPF I+I + + R R I P +E N G Q+F S L +++ KD IY+++ V++
Sbjct: 308 FGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVNITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCSLAILQNYV-KDDKIYVQIDVDR 413
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf6 (gene:FBgn0265464 transcript:FBtr0071188) HSP 1 Score: 50.0618 bits (118), Expect = 9.272e-6 Identity = 32/96 (33.33%), Postives = 45/96 (46.88%), Query Frame = 1
Query: 1285 RCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDL--CQFRSKLQSIGVHMNSCEYR 1566
R +C +C L T CG R C C+ ++ ++ CP DN L E+ +F D T REI QL+ CP C + + H+ SC YR
Sbjct: 101 RYECAICIDWLNEPVLTSCGHRFCRSCLTAWMQKNNQCCP-MDNKRLSAEHDIFPDNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPYR 195
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 84.3445 bits (207), Expect = 2.505e-16 Identity = 81/361 (22.44%), Postives = 149/361 (41.27%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHL-LECINKKKKCPFNQINCNTIDKLSKENLVSH--------------FNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQEL---IMKKFSINAEKCLQNEFR--------------------------SGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHL 2241
+C +C LR+A QT CG R C CI++ + +KCP DN VLL E +LF D REI L V C C + +L+ + H++ C + C +C++ + H +H C RI+TC C S + ++E+ C ++C + + + H +C+ C F+ C +K+++ L H F +++ +N + S ++ S ++ EL ++ +++ EL ++++ E C+ N+ + G ++W++ENF + + + + S FY+ GY C +HL
Sbjct: 70 ECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCP-VDNEVLLEE-QLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCPQCQESVPISHLDEHKSQHCLQRIMTCPDCAGSFVYA------VKQNHEQFCPFANTVCEYCEMELIRDQLALHCDTDCLKAPVACTFSTFGCR--EKMTRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKL-CLRLHL 419
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 84.3445 bits (207), Expect = 2.505e-16 Identity = 81/361 (22.44%), Postives = 149/361 (41.27%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHL-LECINKKKKCPFNQINCNTIDKLSKENLVSH--------------FNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQEL---IMKKFSINAEKCLQNEFR--------------------------SGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHL 2241
+C +C LR+A QT CG R C CI++ + +KCP DN VLL E +LF D REI L V C C + +L+ + H++ C + C +C++ + H +H C RI+TC C S + ++E+ C ++C + + + H +C+ C F+ C +K+++ L H F +++ +N + S ++ S ++ EL ++ +++ EL ++++ E C+ N+ + G ++W++ENF + + + + S FY+ GY C +HL
Sbjct: 70 ECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCP-VDNEVLLEE-QLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCPQCQESVPISHLDEHKSQHCLQRIMTCPDCAGSFVYA------VKQNHEQFCPFANTVCEYCEMELIRDQLALHCDTDCLKAPVACTFSTFGCR--EKMTRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKL-CLRLHL 419
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 84.3445 bits (207), Expect = 2.505e-16 Identity = 81/361 (22.44%), Postives = 149/361 (41.27%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHL-LECINKKKKCPFNQINCNTIDKLSKENLVSH--------------FNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQEL---IMKKFSINAEKCLQNEFR--------------------------SGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHL 2241
+C +C LR+A QT CG R C CI++ + +KCP DN VLL E +LF D REI L V C C + +L+ + H++ C + C +C++ + H +H C RI+TC C S + ++E+ C ++C + + + H +C+ C F+ C +K+++ L H F +++ +N + S ++ S ++ EL ++ +++ EL ++++ E C+ N+ + G ++W++ENF + + + + S FY+ GY C +HL
Sbjct: 70 ECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCP-VDNEVLLEE-QLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCPQCQESVPISHLDEHKSQHCLQRIMTCPDCAGSFVYA------VKQNHEQFCPFANTVCEYCEMELIRDQLALHCDTDCLKAPVACTFSTFGCR--EKMTRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKL-CLRLHL 419
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2a (Tnf receptor-associated factor 2a [Source:ZFIN;Acc:ZDB-GENE-071120-2]) HSP 1 Score: 82.0333 bits (201), Expect = 1.615e-15 Identity = 70/270 (25.93%), Postives = 121/270 (44.81%), Query Frame = 1
Query: 1282 DRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSC-------DNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGV-HMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSX-XXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLK-EDLENNKNIITELFSISKSIQELIMK 2055
D+ C +C K+LR Q +CG R C C + +++G +KC +C + +L + F D A RE+ LE VC + C + ++ H C++R++ C CK+ + A + HN C R + C+YC+ P H ++E+C Y I + + H+ C + C F+ + C+ + KE + H H LL+ I I+ ++ L+ + LE + I EL +S++EL +K
Sbjct: 30 DKHLCNICLKILRRPFQAQCGHRFCSYCFNKAVSSGPQKCSACIKEDIFEEPTSILKQGCAFPDNAAKREVEALEAVCINEECSWTGTIKEYEANHEGKCDFRILPCPSCKELLRANELERHNERECPERTLNCKYCKE--------PFHFKNIKAHDEICPKYPMICEGCAKKKIPREKYVDHIKLCTKFRTPCRFHVVGCDMT--VEKEKIHDHEQACSYEHLNLLLHFIMGIKVNLESLQPQSLELASHKIHELH---QSLRELELK 286 HSP 2 Score: 41.9726 bits (97), Expect = 2.445e-7 Identity = 31/111 (27.93%), Postives = 53/111 (47.75%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTEL----------HSFIFKDKSIYLKLIVN 2516
++ ++IY G RG+HLS+ F ++ G D +L WPF + + + + RE P+I S + V N S L +S+I +D +I++K IV+
Sbjct: 463 KMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNRE-HIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYI-RDDTIFIKAIVD 571 HSP 3 Score: 33.8834 bits (76), Expect = 2.445e-7 Identity = 13/37 (35.14%), Postives = 21/37 (56.76%), Query Frame = 1
Query: 2104 GNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
G F+WKI +F K ++FS +FY+ ++GY
Sbjct: 426 GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGY 462
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 72.7886 bits (177), Expect = 8.898e-13 Identity = 83/384 (21.61%), Postives = 159/384 (41.41%), Query Frame = 1
Query: 1261 FEFTNAPDR-CKCKLCFKVLRNAKQ-TECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVC--PLDLCQFRSKLQSIGVHMNSCEYRVIDC-RKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPF------------NQINCN----------TIDKLSKENLVSHFNKNEIYHNTLLV---------SKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQELI-----MKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY----------NCKCKFIHLGIWI 2253
++F P R +C LC K +R Q + CG R C C+QE+L+ G KCP ++ + L+ K++ D ++I L + C + C++ +++ + H ++C + VI C +C K+T +H + C R V CE+C E H P C++ Q + EC + + C + +Q +C +++E+L +H E + L++ + P + H L+E +++ ++ L + + QE++ M++ S++ + G IWK+ ++ + + + K+ FS FY+ +GY N + HL I+I
Sbjct: 6 YKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCP--EDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCPNRCSVKLTRRDLPEHLQHDCPKRKVKCEFCGSEF-TGEAYENHQGICPQESVYCENKCGARMMRRLLSQHT-----MTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHV--KESCGSALVLCPFKEAGCKHRCPKMAIGRH-LEESTKSHLTMMCSL--VGRQRQEILELRREMEELSVSHD---------GVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYI 367
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: egf (epidermal growth factor [Source:Xenbase;Acc:XB-GENE-951823]) HSP 1 Score: 88.9669 bits (219), Expect = 1.557e-17 Identity = 88/374 (23.53%), Postives = 150/374 (40.11%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCD-DYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSI-----------------------------------HDLKEDLENNKNIITE----LFSISKSIQELIMK-----------KFSI----NAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHLGI 2247
+C +C LR A QT CG R C CI + + KCP DN L+ EN+LF D REI L V CP C +L+ + H+ C++ ++C +C+ Q H C R + CE C ++ L + + ++++ C YV+ N ++ + ++C C + + C +K+ + +L H + H ++ + SS+ +D ++ N + I + L I+ELI K K +I N ++++ SG FIW+I NF+ L+ + I S+ FY+ + GY C +HL +
Sbjct: 71 ECPICLMALREAVQTPCGHRFCKACILKSIRDAGHKCP-VDNESLM-ENQLFPDNFAKREILSLRVKCPSQGCTETMELRHLERHLVRCDFAGVECSQCQSSFPKYSLQKHKFEECPRRQIFCENCALAMALEDKL------NHDQTCPLAYVTCEYCQTNLIREQMPAHYSMDCTMAPIPCMYYEFGCT--EKMQRNDLARHLQEFTQAHMRMMAQTLRSFSSSVTPTSHMPDISFCDPSQFEPAPPSVATVHSSHTPSQNDCTQETRNLRETIEQLEGRLVRQDHQIRELIAKMETQCTYVNELKHTIRSLDNRLGEMESQQCSGIFIWRINNFNSLLKNQEEERPVVIHSQGFYTGKPGYKL-CLRLHLQL 433
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: sytl2 (synaptotagmin like 2 [Source:Xenbase;Acc:XB-GENE-945155]) HSP 1 Score: 87.8113 bits (216), Expect = 1.863e-17 Identity = 85/375 (22.67%), Postives = 161/375 (42.93%), Query Frame = 1
Query: 1294 CKLCFKVLRNAKQ-TECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVC--PLDLCQFRSKLQSIGVHMNSCEYRVIDC-RKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPF------------NQINCN----------TIDKLSKENLVSHFNKNE-------IYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQELI-----MKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHLGIWIVEAVICLFPLKLLTG 2298
C LC K +R Q + CG R C C+QE+L+ G KCP ++ + L+ K++ D+ ++ L + C + C++ +L+ + H+N C + VI C +C K+ +H + C R V CE+C E H P C++ Q L+EC + + CP+ +Q C I +++E+L +H + + ++ + P I S H L+E++ + ++++ L +S+ QE++ +++ S+++E G IWKI ++ + + + K+ F FS FY+ ++GY + G E +++L G
Sbjct: 18 CPLCGKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCP--EDQLPLDYAKIYPDRDLETQVMGLSIRCIHSEEGCRWSGQLKQLQPHLNICAFNVIPCPNRCSTKLIRRDLPEHMQHDCPKRKVRCEFCGADF-TGEAYEDHQGCCPQESVYCENKCGARMMRRVLSQHS-----LVECPKRTQPCPYCNKEFVFDTIQSHQYQCPRYPTPCPNQCGIASIAREDLSNHLKDSCSSALVLCPFKDSGCKHRGPKITISRH-LEENMRAHLSMMSSL--VSRQRQEILELRKQVEELSVSSE---------GVLIWKISDYSRKVQEAKVRGNFESFSPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPG 372
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 74.7146 bits (182), Expect = 3.734e-13 Identity = 67/246 (27.24%), Postives = 119/246 (48.37%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDL--CQFRSKLQSIGVHMNS-CEYRVIDCRK--CKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSX--XXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLK-EDLENNKNI 2004
KC+ C VL N +QTECG R C C+ L++ S +C +C++ + ++K+F D RE+ L++ C + C+ L ++ +H+ S C++ + C + CK+K+ DH C+ R C++C+ + L EM H + D C V + + + HLLEC+N C F + C K + + + +H + + H L+ Y+++ + L+ E E NK+I
Sbjct: 47 KCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNI--TKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQK-HEDVD----CPSVVISCPHMCSVKSLLRSELNAHLLECVNAPSTCSFKRYGCTF--KGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSI 283
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 63.5438 bits (153), Expect = 1.091e-9 Identity = 43/143 (30.07%), Postives = 78/143 (54.55%), Query Frame = 1
Query: 1282 DRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDL--CQFRSKLQSIGVHMNS-CEYRVIDCRK--CKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEM 1695
++ KC+ C VL N +QTECG R C C+ L++ S +C +C++ + ++K+F D RE+ L++ C + C+ L ++ +H+ S C++ + C + CK+K+ DH C+ R C++C+ + L EM
Sbjct: 44 EKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNI--TKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEM 184
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415]) HSP 1 Score: 41.5874 bits (96), Expect = 6.201e-9 Identity = 79/343 (23.03%), Postives = 127/343 (37.03%), Query Frame = 1
Query: 1294 CKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTI---DK-LSKEN--LVSHFNKNEIYHNT------------------LLVSKIPYIQSSIHDLKEDLENNKNIITELF----SISKSIQELIMKKFSINAE---KCLQNEFRS--GNFIWKIENFDKL---IIKGKMCERFSIFSKSFYSDEFGY 2214
C C +LR Q +CG R C C+ + + +V N + + VC + + L S+G H C Y + C CK I A + H+ C R + C YC+ S + I H +E+C + C +K R L C+ C + + C + DK L EN L H K L K ++ + L ++E + + EL + ++ + +K I AE + ++E + G FIWKI F K I G+ C ++FS FY++++GY
Sbjct: 37 CSDCKNLLRRPLQAQCGHRYCSHCLNKII-----------RWVARNWGG----------VPECPAVC--ERSDWTGALISVG-HEGKCPYLLAPCPACKTIIRAANRDLHSERECPERKLNCRYCKLSFYFPD-IKAH-----DEICPKFPMTCEGCGRKKIPREKVR-LFVCM----PCRYAAVGCTEMVENDKCLEHENKSLAEHLAKGSPAPPANAPPNNSAKVAEMLLKFDTLDKKNTTFENIVSVLNREVERSSHAAEELARQLRAADTRLERTLGQKELIVAELETRMQESELSTYDGVFIWKISEFGKKRQDAINGR-CP--AMFSPPFYTNKYGY 341 HSP 2 Score: 40.4318 bits (93), Expect = 6.201e-9 Identity = 27/110 (24.55%), Postives = 51/110 (46.36%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTELHSFIFK---------DKSIYLKLIVN 2516
++ ++IY G R +HLS+ F ++ G+ D +L WPF + + + + RE P++ S + + N S L + K D +I++K+IV+
Sbjct: 342 KMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNNRE-HVIDAFRPDVSSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIVD 450
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf6 (TNF receptor-associated factor 6 [Source:MGI Symbol;Acc:MGI:108072]) HSP 1 Score: 93.9745 bits (232), Expect = 4.912e-21 Identity = 96/360 (26.67%), Postives = 150/360 (41.67%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKI-----------------------PYIQSSIHDLKEDLENNKNIITELFS-----------ISKSIQELIMKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCER-FSIFSKSFYSDEFGYNCKCKFIHLGIWIVE 2259
+C +C LR A QT CG R C CI + + KCP DN +LL EN+LF D REI L V CP C + +L+ + H CE+ +++C +C++ H I C R V+C C S+ E IH P +C +Y ++ + L+C C F+ C+ +K+ + +L H +N H LL + P + +I L+ L + I EL + + ++I+ L K + A++C +G +IWKI NF + +K + ER I S FY+ GY C +HL + +
Sbjct: 69 ECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCP-VDNEILL-ENQLFPDNFAKREILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCPQCQRPFQKCQVNTHIIEDCPRRQVSCVNCAVSMAYEEK-EIHDQSCPLANIIC-EYCG-----TILIREQMPNHYDLDCPTAPIPCTFSVFGCH--EKMQRNHLARHLQENTQLHMRLLAQAVHNVNLALRPCDAASPSRGCRPEDPNYEETIKQLESRLVRQDHQIRELTAKMETQSMYVGELKRTIRTLEDKVAEMEAQQC------NGIYIWKIGNFG-MHLKSQEEERPVVIHSPGFYTGRPGYKL-CMRLHLQLPTAQ 409 HSP 2 Score: 28.4906 bits (62), Expect = 4.912e-21 Identity = 10/32 (31.25%), Postives = 19/32 (59.38%), Query Frame = 3
Query: 2259 GSHLSVSFEIINGDYDQILSWPFKHNIQIGIF 2354
+++S+ + G+YD L WPF+ I++ I
Sbjct: 412 ANYISLFVHTMQGEYDSHLPWPFQGTIRLTIL 443
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 80.8777 bits (198), Expect = 9.255e-21 Identity = 79/363 (21.76%), Postives = 147/363 (40.50%), Query Frame = 1
Query: 1294 CKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSC-------DNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSI-GVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDY-VSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKE---DLENNKNIITELFSISKSIQELI---MKKFSINAEKC-------------LQNEFR----------------------------SGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
C C +LR Q +CG R C C+ L++G + C +C + +L + F D A RE+ L VCP D C ++ L+ H C + + +C CK + ++ H C R ++C++C R+ + + +H E+C + ++ + + + H+ C + C F+ + C+ + + ENL H + H LL+S Q+S L + +L I+ + + ++I ++ +++ ++ AE C L N+ + G FIWKI +F + + +IFS +FY+ +GY
Sbjct: 34 CSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHC-RAPCSHVDLEVHY-----EVCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEM--VETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGY 388 HSP 2 Score: 40.4318 bits (93), Expect = 9.255e-21 Identity = 28/110 (25.45%), Postives = 49/110 (44.55%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTELHSFIFK---------DKSIYLKLIVN 2516
++ +++Y G RG+HLS+ F ++ G D +L WPF + + + RE P++ S + V N S L + K D +I++K IV+
Sbjct: 389 KMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNRE-HVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 73.9442 bits (180), Expect = 1.134e-18 Identity = 79/370 (21.35%), Postives = 147/370 (39.73%), Query Frame = 1
Query: 1294 CKLCFKVLRNAKQTECGCRVCGQCIQEYL-------AAGSRKCPSC-------DNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSI-GVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDY-VSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKE---DLENNKNIITELFSISKSIQELI---MKKFSINAEKC-------------LQNEFR----------------------------SGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
C C +LR Q +CG R C C+ L ++G + C +C + +L + F D A RE+ L VCP D C ++ L+ H C + + +C CK + ++ H C R ++C++C R+ + + +H E+C + ++ + + + H+ C + C F+ + C+ + + ENL H + H LL+S Q+S L + +L I+ + + ++I ++ +++ ++ AE C L N+ + G FIWKI +F + + +IFS +FY+ +GY
Sbjct: 34 CSACKNILRRPFQAQCGHRYCSFCLTSILRCASILSSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHC-RAPCSHVDLEVHY-----EVCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEM--VETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGY 395 HSP 2 Score: 40.4318 bits (93), Expect = 1.134e-18 Identity = 28/110 (25.45%), Postives = 49/110 (44.55%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTELHSFIFK---------DKSIYLKLIVN 2516
++ +++Y G RG+HLS+ F ++ G D +L WPF + + + RE P++ S + V N S L + K D +I++K IV+
Sbjct: 396 KMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNRE-HVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 504
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 81.2629 bits (199), Expect = 3.081e-15 Identity = 69/247 (27.94%), Postives = 118/247 (47.77%), Query Frame = 1
Query: 1282 DRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLD--LCQFRSKLQSIGVHM-NSCEYRVIDCRK--CKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLK-EDLENNKNI 2004
D+ KC+ C VL N KQTECG R C C+ L++ S KC +C ++ ++K+F D REI L+V C + C + L + VH+ N C++ + C + CK+K+ +DH C+ R TC +C+ + MI + + D + C + + + HL EC+N C F + C + + + + + +H + + H LL ++ + L+ E +E NK+I
Sbjct: 48 DKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESII--KDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVP---MIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGC--VFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSI 287
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf4 (TNF receptor associated factor 4 [Source:MGI Symbol;Acc:MGI:1202880]) HSP 1 Score: 71.633 bits (174), Expect = 2.205e-12 Identity = 85/378 (22.49%), Postives = 156/378 (41.27%), Query Frame = 1
Query: 1261 FEFTNAPDR-CKCKLCFKVLRNAKQ-TECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVC--PLDLCQFRSKLQSIGVHMNSCEYRVIDC-RKCKQKITAIHEQDHNINLCEMRIVTCEYC-----------------QRSIKLN-----EMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKN-------EIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKS-IQELI--MKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY----------NCKCKFIHLGIWI 2253
++F P R C LC K +R Q + CG R C C+QE+L+ G KCP ++ + L+ K++ D ++ L + C + C++ L+ + H+N+C + V+ C +C K++ H + C R + CE+C Q S+ M+ L C C + I+ H +C CP NQ T+ ++E+L +H + + + + P + H ++E ++ + ++ L S + +QEL +++ SI ++ G IWKI ++ + + + K FS +FY+ ++GY N + HL I+I
Sbjct: 6 YKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCP--EDQLPLDYAKIYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCP-NQCGVGTV---AREDLPTHLKDSCSTAFVLCPFKESGCKHRCPKLAMGRH-VEESVKPHLAMMCALVSRQRQELQELRRELEELSIGSD---------GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYI 367
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q9Y4K3|TRAF6_HUMAN (TNF receptor-associated factor 6 OS=Homo sapiens OX=9606 GN=TRAF6 PE=1 SV=1) HSP 1 Score: 105.531 bits (262), Expect = 1.248e-23 Identity = 95/351 (27.07%), Postives = 154/351 (43.87%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLL---------------VSKIPYIQSSIHDLKEDLENNKNIITELFS-----------ISKSIQELIMKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHLGIWIVE 2259
+C +C LR A QT CG R C CI + + KCP DN +LL EN+LF D REI L V CP + C + +L+ + H CE+ ++DC +C++ H H + C R V+C+ C S+ + IH P +C+ N ++ + L+C C F+ C+ +K+ + +L H +N H +L +S++ Q +IH L+ L + I EL + + ++I+ L K I A++C +G +IWKI NF + + + I S FY+ + GY C +HL + +
Sbjct: 69 ECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCP-VDNEILL-ENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDK-EIHDQNCPLANVICE------YCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCH--EKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQC------NGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKL-CMRLHLQLPTAQ 401 HSP 2 Score: 28.4906 bits (62), Expect = 1.248e-23 Identity = 10/32 (31.25%), Postives = 19/32 (59.38%), Query Frame = 3
Query: 2259 GSHLSVSFEIINGDYDQILSWPFKHNIQIGIF 2354
+++S+ + G+YD L WPF+ I++ I
Sbjct: 404 ANYISLFVHTMQGEYDSHLPWPFQGTIRLTIL 435
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|B6CJY5|TRAF6_MACMU (TNF receptor-associated factor 6 OS=Macaca mulatta OX=9544 GN=TRAF6 PE=2 SV=1) HSP 1 Score: 104.76 bits (260), Expect = 2.044e-23 Identity = 95/351 (27.07%), Postives = 153/351 (43.59%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLL---------------VSKIPYIQSSIHDLKEDLENNKNIITELFS-----------ISKSIQELIMKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHLGIWIVE 2259
+C +C LR A QT CG R C CI + + KCP DN +LL EN+LF D REI L V CP + C + +L+ + H CE+ ++DC +C++ H H + C R V+C+ C + + IH P +C+ N ++ + L+C C F+ C+ +K+ + +L H +N H +L VS++ Q +IH L+ L + I EL + + ++I+ L K I A++C +G +IWKI NF + + + I S FY+ + GY C +HL + +
Sbjct: 69 ECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCP-VDNEILL-ENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALVDCPQCQRPFQKFHINIHILKDCPRRQVSCDNCAALVAFEDK-EIHDQNCPLANVICE------YCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCH--EKMQRNHLARHLQENTQSHMRMLAQAVHSLSLIPDSGYVSEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSTYVSELKRTIRTLEDKVAEIEAQQC------NGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKL-CMRLHLQLPTAQ 401 HSP 2 Score: 28.4906 bits (62), Expect = 2.044e-23 Identity = 10/32 (31.25%), Postives = 19/32 (59.38%), Query Frame = 3
Query: 2259 GSHLSVSFEIINGDYDQILSWPFKHNIQIGIF 2354
+++S+ + G+YD L WPF+ I++ I
Sbjct: 404 ANYISLFVHTMQGEYDSHLPWPFQGTIRLTIL 435
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|B6CJY4|TRAF6_CERAT (TNF receptor-associated factor 6 OS=Cercocebus atys OX=9531 GN=TRAF6 PE=2 SV=1) HSP 1 Score: 104.76 bits (260), Expect = 2.112e-23 Identity = 95/351 (27.07%), Postives = 153/351 (43.59%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLL---------------VSKIPYIQSSIHDLKEDLENNKNIITELFS-----------ISKSIQELIMKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHLGIWIVE 2259
+C +C LR A QT CG R C CI + + KCP DN +LL EN+LF D REI L V CP + C + +L+ + H CE+ ++DC +C++ H H + C R V+C+ C + + IH P +C+ N ++ + L+C C F+ C+ +K+ + +L H +N H +L VS++ Q +IH L+ L + I EL + + ++I+ L K I A++C +G +IWKI NF + + + I S FY+ + GY C +HL + +
Sbjct: 69 ECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCP-VDNEILL-ENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALVDCPQCQRPFQKFHINIHILKDCPRRQVSCDNCAALVAFEDK-EIHDQNCPLANVICE------YCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCH--EKMQRNHLARHLQENTQSHMRMLAQAVHSLSLIPDSGYVSEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSTYVSELKRTIRTLEDKVAEIEAQQC------NGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKL-CMRLHLQLPTAQ 401 HSP 2 Score: 28.4906 bits (62), Expect = 2.112e-23 Identity = 10/32 (31.25%), Postives = 19/32 (59.38%), Query Frame = 3
Query: 2259 GSHLSVSFEIINGDYDQILSWPFKHNIQIGIF 2354
+++S+ + G+YD L WPF+ I++ I
Sbjct: 404 ANYISLFVHTMQGEYDSHLPWPFQGTIRLTIL 435
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P70196|TRAF6_MOUSE (TNF receptor-associated factor 6 OS=Mus musculus OX=10090 GN=Traf6 PE=1 SV=2) HSP 1 Score: 93.9745 bits (232), Expect = 2.997e-20 Identity = 96/360 (26.67%), Postives = 150/360 (41.67%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKI-----------------------PYIQSSIHDLKEDLENNKNIITELFS-----------ISKSIQELIMKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCER-FSIFSKSFYSDEFGYNCKCKFIHLGIWIVE 2259
+C +C LR A QT CG R C CI + + KCP DN +LL EN+LF D REI L V CP C + +L+ + H CE+ +++C +C++ H I C R V+C C S+ E IH P +C +Y ++ + L+C C F+ C+ +K+ + +L H +N H LL + P + +I L+ L + I EL + + ++I+ L K + A++C +G +IWKI NF + +K + ER I S FY+ GY C +HL + +
Sbjct: 69 ECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCP-VDNEILL-ENQLFPDNFAKREILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCPQCQRPFQKCQVNTHIIEDCPRRQVSCVNCAVSMAYEEK-EIHDQSCPLANIIC-EYCG-----TILIREQMPNHYDLDCPTAPIPCTFSVFGCH--EKMQRNHLARHLQENTQLHMRLLAQAVHNVNLALRPCDAASPSRGCRPEDPNYEETIKQLESRLVRQDHQIRELTAKMETQSMYVGELKRTIRTLEDKVAEMEAQQC------NGIYIWKIGNFG-MHLKSQEEERPVVIHSPGFYTGRPGYKL-CMRLHLQLPTAQ 409 HSP 2 Score: 28.4906 bits (62), Expect = 2.997e-20 Identity = 10/32 (31.25%), Postives = 19/32 (59.38%), Query Frame = 3
Query: 2259 GSHLSVSFEIINGDYDQILSWPFKHNIQIGIF 2354
+++S+ + G+YD L WPF+ I++ I
Sbjct: 412 ANYISLFVHTMQGEYDSHLPWPFQGTIRLTIL 443
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P39429|TRAF2_MOUSE (TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1) HSP 1 Score: 80.8777 bits (198), Expect = 5.647e-20 Identity = 79/363 (21.76%), Postives = 147/363 (40.50%), Query Frame = 1
Query: 1294 CKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSC-------DNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSI-GVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDY-VSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKE---DLENNKNIITELFSISKSIQELI---MKKFSINAEKC-------------LQNEFR----------------------------SGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
C C +LR Q +CG R C C+ L++G + C +C + +L + F D A RE+ L VCP D C ++ L+ H C + + +C CK + ++ H C R ++C++C R+ + + +H E+C + ++ + + + H+ C + C F+ + C+ + + ENL H + H LL+S Q+S L + +L I+ + + ++I ++ +++ ++ AE C L N+ + G FIWKI +F + + +IFS +FY+ +GY
Sbjct: 34 CSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHC-RAPCSHVDLEVHY-----EVCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEM--VETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGY 388 HSP 2 Score: 40.4318 bits (93), Expect = 5.647e-20 Identity = 28/110 (25.45%), Postives = 49/110 (44.55%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTELHSFIFK---------DKSIYLKLIVN 2516
++ +++Y G RG+HLS+ F ++ G D +L WPF + + + RE P++ S + V N S L + K D +I++K IV+
Sbjct: 389 KMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNRE-HVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: D5JG59 (TNF receptor-associated factor-2-like protein A OS=Dugesia japonica OX=6161 GN=TRAF-2A PE=2 SV=1) HSP 1 Score: 142.895 bits (359), Expect = 5.368e-41 Identity = 93/238 (39.08%), Postives = 143/238 (60.08%), Query Frame = 1
Query: 1543 HMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFS-----------ISKSIQELIMKKFSINAEKCLQNE---FRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
H+ SC+ R I C KC K A + +H+ + CEMR+V C+YC ++K ++ IHLNPD +E+C YV IC NNCN+ +++N+K HL C NKK +CPF+Q +C IDK++KE L+ H ++ H + L++K+ ++S I DL+ +L N I ELF I K+I+EL KK + + + N+ FR+ +FIWK +F+ + + R S+ S +FY+ EFGY
Sbjct: 4 HIESCDLREITCEKCGIKFGAKEKANHDKDKCEMRMVNCDYCGITMKSKDLNIIHLNPDRDELCSKYVGICSNNCNETRKVNLKDHLKICPNKKLECPFHQFDCK-IDKMTKEKLMKHLDEEYFNHTSSLINKVKDLESKIIDLESELHNQILITKELFEMNKKSSESRLKIEKTIEEL-KKKAPATSIQTIDNKNVIFRNASFIWKFTDFEVRRVDAESGGRVSVTSDAFYTSEFGY 239 HSP 2 Score: 57.3806 bits (137), Expect = 5.368e-41 Identity = 35/110 (31.82%), Postives = 58/110 (52.73%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDS-----PHE--NQFVGIQNF--LSFTELHSFIFKDKSIYLKLIVN 2516
++ +++YP G +G+HLSV F I+ G++D +LSWPFK + + I +E+ T P+ S P + N G F LS +S K+ +I+LK+ V+
Sbjct: 240 KMCLRVYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSILDQESGSKPHSDTFKPDARSACYQKPTDECNIASGFPKFILLSLIMNNSIYCKNDTIFLKIAVD 349
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: D5JG60 (TNF receptor-associated factor-2-like protein B OS=Dugesia japonica OX=6161 GN=TRAF-2B PE=2 SV=1) HSP 1 Score: 165.622 bits (418), Expect = 3.197e-40 Identity = 113/353 (32.01%), Postives = 184/353 (52.12%), Query Frame = 1
Query: 1237 IMNYDMRLFEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLK-EDLENN------KNIITELFSISKSIQELIMKKFSINAEKCLQNE---FRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHLGIWIVEAV 2265
I Y + F F N D KC +C ++L A QT+CGCR C +C++EY A G KC + L N + D A REI +L V C C+ L+ IG H++SC ++ I+C+ C +++T I ++H C MR+V+C +C ++ + + +HLN E++C V CP C+ +++N+ H C K C F++I CN + ++KE+L+ H N+ + H+ LL+ +I +++ I +LK + LE N +E+ KS++++ + E +R+G FIWKIE F +L + + R SI S FY+ EFGY K G + +
Sbjct: 12 IKRYRKKHFPF-NISDNLKCIICSQLLLEALQTDCGCRYCKECLKEYQAKGKTKCLTDGCGDLGN---IIPDNAVNREIGKLTVKCLFPGCEHSELLKDIGDHLDSCIHQTINCKSCNEELTKIELKEHTEKKCPMRLVSCTHCGEEMEYSNLTELHLNVHTEKLCAKLVGKCPYKCDNGKEVNLLDHRKSCSKKPVTCLFSEIGCNRV--MTKEDLIKHNNEESLQHSRLLMKEIITMKNDISELKMKTLEFNILKIEFSKFQSEILDKIKSLEKIPRHTSPSTSSVRSSEEKTVYRNGVFIWKIERFSELKSEAERGNRISITSDYFYTKEFGYKMSMKIYPAGDGVGKGT 358
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1DBK6 (TRAF-4 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 133.265 bits (334), Expect = 3.468e-29 Identity = 114/421 (27.08%), Postives = 199/421 (47.27%), Query Frame = 1
Query: 1282 DRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPS----CDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQELI-----MKKFSINAEKCLQNE----FRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHLGIWIVEAVICLFPLKLLTG---IMTKYCHGHLNIIYRLEFFTEKRVNCPAVKQLHPKSI----PRTRINLWESKIFYLSLNCIRLFLK 2484
D KC +C +L +A QT+CGCR C +CI YL G ++C + C + + D+AT +EI+ L+V C + C F L+SI H++ CEYR C C + E +H N C +R V C+YC+ + E HL ++ ++C Y +ICP C + ++N+ H C NK +CP + +C + + K+ + H N + H +V+++ ++ ++E + NI+ E + K+ E++ SI+ + L+ FR+G ++WKI++F KL + +I S++FY+ +FGY K G + + ++ G + + + II + F+ K N + PKSI P N+ ++S + ++ FLK
Sbjct: 27 DNLKCVMCQDILLDAIQTDCGCRYCKECIDNYLENGEKECVAEYEDCRSVI----TSYIYDRATNKEISLLKVKCLYEGCVFEDTLKSIKGHLDFCEYRNEMCSLCGMEYIIKEESNHLANECLLREVLCQYCRTLLTFKEYNESHLCFESRDLCGKYEAICPYGCTGESKVNLLHHRKSCENKPLECPLHVFDCKQL--IPKDQMTEHLNTSSYEHTLTIVTELRKLEKQNKHMEERM----NILIEENQLLKATLEVMKLDLPKNSGSISRDTSLKRANKTIFRNGKYMWKIKSFSKLRENAMRGKNPTILSEAFYTSDFGYKMCMKIYPCGDGVGKGTHLSIFFVIMKGDYDDILPWPFKNKVIITIFDDFS-KSTNLSDTFKPDPKSICYQRPEEEYNIASGSPKFISFSELKNFLK 436 HSP 2 Score: 68.1662 bits (165), Expect = 5.161e-8 Identity = 41/107 (38.32%), Postives = 63/107 (58.88%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDS-----PHE--NQFVGIQNFLSFTELHSFIFKDKSIYLKLIV 2513
++ M+IYP G +G+HLS+ F I+ GDYD IL WPFK+ + I IF ++ + T P+ S P E N G F+SF+EL +F+ KD ++Y+++ V
Sbjct: 341 KMCMKIYPCGDGVGKGTHLSIFFVIMKGDYDDILPWPFKNKVIITIFDDFSKSTNLSDTFKPDPKSICYQRPEEEYNIASGSPKFISFSELKNFLKKD-TLYIQINV 446
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1DF65 (TRAF-2 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 115.161 bits (287), Expect = 2.924e-28 Identity = 101/342 (29.53%), Postives = 155/342 (45.32%), Query Frame = 1
Query: 1261 FEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDN--EEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDL----ENNKNIITE----LFSISKSIQEL--IMKKFSINAEKCLQNEF------------RSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
FE R C C +VL QT+CGCR+C C++E CP C+ + N DKA +EI +L ++C C++ K++ + H+ +CEY C C + + H C+M I TCE C + ++ H N + + +C + ICP C++ +NIK HLL C + +C N++ C + L +E + HFN YH LL+ + ++ DL + E N I E L S+ I++L +K+F EK L+NE R G + WK+EN + + K I S+SFYS GY
Sbjct: 21 FECEQQKQRISCVKCHQVLIEPYQTQCGCRLCSNCLEECSKDEESHCPGCNETMNSPSNYSKHDKAIEKEILELNIICTNKGCEYTCKVKDLDNHLETCEYIEKRCTACNESYPRKELKKHEEFTCKMIITTCEDCGLELSKGDLEKKHKNVNELIDNVCSKWRDICPFKCSEDTLVNIKDHLLTCERRPVECSLNEMGCRKV--LPREEMREHFNLEANYHTVLLMDALFLLRKEHQDLSVSVSVQNERNSAEIKELKEKLSSLLTEIEDLKTKLKQFQSMYEK-LENERNLAKCSLSETKERYGEYTWKVENIMEKVNDAKKGVNTQILSESFYSSNPGY 359 HSP 2 Score: 41.9726 bits (97), Expect = 2.924e-28 Identity = 33/109 (30.28%), Postives = 51/109 (46.79%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDS-----PHE--NQFVGIQNFLSFTEL--HSFIFKDKSIYLKLIV 2513
++ ++IYP G G++LSV F ++ G YD + WPF I I + + R R + P I+ P E N G F+S +L KD +I L++ V
Sbjct: 360 RMCLKIYPNGDGSAFGNYLSVYFVLMKGKYDDQIQWPFNSIISIRLVNIARRGEDRVLNMRPNINDQCYGRPKEEHNLAAGQPKFVSHLQLVNEDDFIKDGAIILRVNV 468
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T2M357 (TNF receptor-associated factor 6 (Fragment) OS=Hydra vulgaris OX=6087 GN=TRAF6 PE=2 SV=1) HSP 1 Score: 104.76 bits (260), Expect = 2.120e-23 Identity = 105/368 (28.53%), Postives = 155/368 (42.12%), Query Frame = 1
Query: 1276 APDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVC---PLDLCQFRSKLQSIGVHMNSCEYRVIDCR-KCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDY----------VSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKEN---------------------LVSHFNKNEIYHNTLLVSK----IPY---IQSSIHDLKEDLENNKNIITELFSISKS-----IQELIMKKFSINAEKCLQNEF--------RSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
APD +C +C VL QTECG R C CI + L G CP DNY +NE +++ D +REI +L+V C C++ L+S+ HM SCEY + C C +K+T H +N C R+++CEYC+ I ++ D+ E C+ + V I ++ R +L+C K C F + L EN ++ F + EI N S P+ ++SI ++LE N + + +S EL + SI+ E QNE GNFIW+I NFD+L + E +I S FY+ GY
Sbjct: 40 APDVYECPICLLVLNAPVQTECGHRFCRGCILKVLREGRPNCP-IDNYS-INEEQIYPDNFALREILELKVRCQNSKTHNCKWLGSLKSLKEHMMSCEYNLFPCSNNCGEKMTRNALDKHILNDCPKRVISCEYCKLKIVFKKL------QDHYERCEGFPVNCPNVCEVVVIPRGKLKIHMEVECSRAILKCSYKDTGCEFQGTRDEVANHLKTENHQTMLLQMLCDLKLKVANQEKVIESFKEKEITFNKEFQSSNGAGYPFSLKPEASIVGRFDELEKKINQVKATSEVCRSELKHTRSELESRIESISIEVKAQNEVINEVSARTWKGNFIWRISNFDQLFRQALSGEVPAIHSLPFYTGVPGY 399 HSP 2 Score: 36.1946 bits (82), Expect = 2.120e-23 Identity = 14/47 (29.79%), Postives = 29/47 (61.70%), Query Frame = 3
Query: 2259 GSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSR-CQTIA 2396
G+H+S+ ++ G++D ++ WPF N+ I ++TR+ C+T+
Sbjct: 415 GTHVSMFVHMMQGEFDSLIEWPFPGNVIFTILDQDTRDPQHVCETLT 461
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 63.1586 bits (152), Expect = 4.856e-16 Identity = 72/352 (20.45%), Postives = 130/352 (36.93%), Query Frame = 1
Query: 1282 DRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSI-GVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSX-XXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLV----SKIPYIQSSIHDLKEDLENNKNIITEL---FSISKSIQELIMKKFSINAEK--CLQNEFR----------------------------SGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
D+ C +C K+LR Q +CG R + F D A RE+ LE VC + C + ++ H C++ +I C CK+ + A + HN C R + C+YC+ P H ++E+C Y I + + H+ C + C F+ + C+ + NL+ ++ + + V +K+ + +L+ + +NI+ L S + E ++ ++ +K L N+ R G F+WKI +F K ++FS +FY+ ++GY
Sbjct: 30 DKHLCNICQKILRRPFQAQCGHR-------------------------FSPASAFPDNAAKREVEALEAVCINEGCSWTGTIKEYEATHEGQCDFMIIPCPSCKELLRANELERHNERECPERTLNCKYCKE--------PFHFKNIKAHDEICPKYPMICEGCAKKKIPREKYVDHIKLCTKFRTPCRFHVVGCDMSVSKPQWNLI--LTPRDLLYTSFTVPLSQTKVAELSRRCQELELKVGTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGY 346 HSP 2 Score: 41.9726 bits (97), Expect = 4.856e-16 Identity = 31/111 (27.93%), Postives = 53/111 (47.75%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTEL----------HSFIFKDKSIYLKLIVN 2516
++ ++IY G RG+HLS+ F ++ G D +L WPF + + + + RE P+I S + V N S L +S+I +D +I++K IV+
Sbjct: 347 KMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNRE-HIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYI-RDDTIFIKAIVD 455
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 82.4185 bits (202), Expect = 9.514e-16 Identity = 72/282 (25.53%), Postives = 125/282 (44.33%), Query Frame = 1
Query: 1282 DRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSC-------DNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSI-GVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSX-XXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLK-EDLENNKNIITELFSISKSIQELIMKKFSINAEKCLQN 2091
D+ C +C K+LR Q +CG R C C + +++G +KC +C + +L + F D A RE+ LE VC + C + ++ H C++ +I C CK+ + A + HN C R + C+YC+ P H ++E+C Y I + + H+ C + C F+ + C+ + KE + H H LL+ I I+ ++ L+ + LE + I EL +S++EL +K ++A +Q
Sbjct: 30 DKHLCNICQKILRRPFQAQCGHRFCSYCFNKTVSSGPQKCSACIKEDIFEEPTSILKQGCAFPDNAAKREVEALEAVCINEGCSWTGTIKEYEATHEGQCDFMIIPCPSCKELLRANELERHNERECPERTLNCKYCKE--------PFHFKNIKAHDEICPKYPMICEGCAKKKIPREKYVDHIKLCTKFRTPCRFHVVGCDM--SVEKEKIHDHERACSYEHLNLLLHFIMGIKVNLESLQPQSLELASHKIQELH---QSLRELELKMGQLSAGAPVQG 298 HSP 2 Score: 41.5874 bits (96), Expect = 2.324e-7 Identity = 31/111 (27.93%), Postives = 53/111 (47.75%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTEL----------HSFIFKDKSIYLKLIVN 2516
++ ++IY G RG+HLS+ F ++ G D +L WPF + + + + RE P+I S + V N S L +S+I +D +I++K IV+
Sbjct: 460 KMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNRE-HIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYI-RDDTIFIKAIVD 568 HSP 3 Score: 33.8834 bits (76), Expect = 2.324e-7 Identity = 13/37 (35.14%), Postives = 21/37 (56.76%), Query Frame = 1
Query: 2104 GNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
G F+WKI +F K ++FS +FY+ ++GY
Sbjct: 423 GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGY 459
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:103028261]) HSP 1 Score: 78.9518 bits (193), Expect = 1.046e-14 Identity = 58/231 (25.11%), Postives = 100/231 (43.29%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCD-------NYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGV-HMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDY-VSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQ 1956
+C+ C VLR Q +CG R C C ++ ++G C +C + +L+ + F D A REI+ L CP D C + L+ V H CE+ + C C+ I + HN CE R + C+YC+ + + I H +E+C + + + + H C K C F++I C + K++ H + I H L+++ + ++
Sbjct: 41 QCQQCKGVLRKPFQAQCGHRFCVFCFKQLTSSGPIPCEACRAEGIFEMEHSMLSITEAFPDNAARREIDGLPAKCPNDGCSWNGTLKEYEVQHEGRCEFERVKCEACQMMILLSDKDRHNERECEARTLNCKYCKVTFSFKD-IKAH-----DEICQKFPMQCKDCGKKKIPREKFAEHSKSCAKSKSACQFSEIGCRAVVDNGKQH--EHEQSSIIEHLRLMLAVLSTVR 263 HSP 2 Score: 45.8246 bits (107), Expect = 1.901e-8 Identity = 30/110 (27.27%), Postives = 51/110 (46.36%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTEL---------HSFIFKDKSIYLKLIVN 2516
++ +++Y G RGSHLS+ F ++ G YD +L WPF + + + + RE P+I S + + N S L S +D +I++K IV+
Sbjct: 419 KMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQNNRE-HIIDAFRPDISSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 527 HSP 3 Score: 33.8834 bits (76), Expect = 1.901e-8 Identity = 13/37 (35.14%), Postives = 21/37 (56.76%), Query Frame = 1
Query: 2104 GNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
G F+WKI +F + ++FS +FYS ++GY
Sbjct: 382 GVFVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGY 418
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:103024022]) HSP 1 Score: 75.8702 bits (185), Expect = 8.501e-14 Identity = 83/389 (21.34%), Postives = 159/389 (40.87%), Query Frame = 1
Query: 1237 IMNYDMRLFEFTNAPDRCKCKLCFKVLRNAKQ-TECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVC--PLDLCQFRSKLQSIGVHMNSCEYRVIDC-RKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPF------------NQINCN----------TIDKLSKENLVSHFNKN-------EIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQELI-----MKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY----------NCKCKFIHLGIWI 2253
+ YD + E R +C LC K +R Q + CG R C C+QE+L+ G KCP ++ + L+ K++ D ++I L + C + C++ +++ + H ++C + VI C +C K+T +H + C R V CE+C E H P C++ Q + EC + + C + +Q +C +++E+L +H ++ + + + P + H L+E +++ ++ L + + QE+I M++ S++ + G IWK+ ++ + + + K+ FS FY+ +GY N + HL I+I
Sbjct: 1 MPGYDYKFLE--KPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCP--EDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCAVKLTRRDLPEHLQHDCPKRKVKCEFCGSEF-TGEAFENHQGICPQESVYCENKCGARMMRRLLAQHT-----MAECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLATHVKESCGSALVLCPFKDAGCKHRCPKLAIGRH-LEETTKSHLTMMCSL--VGRQRQEIIELRREMEELSVSHD---------GVLIWKLNDYSRKLQEAKLHNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYI 367
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 70.8626 bits (172), Expect = 3.906e-12 Identity = 43/130 (33.08%), Postives = 69/130 (53.08%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSI 1680
+C +C LR+A QT CG R C CI++ + +KCP DN VL E++LF D REI L V C C + +L+ + H+ C++ + C +C++ + ++H C R++TC C +I
Sbjct: 69 ECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQKCP-VDNEVL-TEDQLFPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQESVWKSELEEHINQECSHRLITCPDCAENI 196
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 78.5666 bits (192), Expect = 3.693e-15 Identity = 64/221 (28.96%), Postives = 101/221 (45.70%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCI--QEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHL-LECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKI 1944
+C +C LR QT CG R C CI L KCP DN VL +E +LF D REI L V CP C R +L+++ H CEY + C +C+ + H C RIVTC +C + + + ++E+MC V C + + + + HL ++C + C F+ + C ++ + L +H +++ H LL + +
Sbjct: 64 ECPICLMALREPVQTPCGHRFCRACILHSMRLRDAGPKCP-VDNAVL-HEGQLFPDNFAKREILSLTVRCPNKPCGHRGELRALQEHQLRCEYAQVPCVRCEMPVCRRDLAKHEEQECMRRIVTCLHCCEKMAYKD------SKNHEQMCPLVVVNCKHCQQELIREQLGPHLEVDCQQAQVPCTFSPLGCEA--QMVRSLLAAHMHEHTQVHMRLLANGL 274
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 49.6766 bits (117), Expect = 1.125e-10 Identity = 31/113 (27.43%), Postives = 52/113 (46.02%), Query Frame = 3
Query: 2235 PFGYLDC-----------RGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPH-------ENQFVGIQNFLSFTELHSFIF-KDKSIYLKLIVN 2516
PFGY C RG+HLS+ F ++ G+YD +L WPF+ + + + + T P+ S N G F+S L S + +D +I++K++V+
Sbjct: 358 PFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFKPDPASSSFRRPTSDMNIASGCPLFVSHVALESASYLQDDTIFIKVVVD 470 HSP 2 Score: 35.039 bits (79), Expect = 1.125e-10 Identity = 17/69 (24.64%), Postives = 34/69 (49.28%), Query Frame = 1
Query: 2008 TELFSISKSIQELIMKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
T+LF+ + E+ ++ F + L+ +G +WKI ++ + S++S+ FY+ FGY
Sbjct: 299 TQLFAHDTRLAEMDLR-FQV-----LETASYNGKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGY 361
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 45.8246 bits (107), Expect = 5.241e-10 Identity = 30/113 (26.55%), Postives = 52/113 (46.02%), Query Frame = 3
Query: 2235 PFGYLDC-----------RGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDS-----PHENQFV--GIQNFLSFTELH-SFIFKDKSIYLKLIVN 2516
PFGY C RG+HLS+ F ++ G+YD +L WPF+ + + + + T P+ S P + V G F+S L S D +++++++V+
Sbjct: 301 PFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPDPASGSFRRPDGDMNVASGCPLFVSHVALEGSSYLVDDTVFVRVVVD 413 HSP 2 Score: 36.1946 bits (82), Expect = 5.241e-10 Identity = 13/46 (28.26%), Postives = 24/46 (52.17%), Query Frame = 1
Query: 2077 KCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
+ L+ SG +WKI ++ + + S++S+ FY+ FGY
Sbjct: 259 QVLETAGYSGKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGY 304
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008091.1 (pep scaffold:Pmarinus_7.0:GL477915:34322:50582:-1 gene:ENSPMAG00000007312.1 transcript:ENSPMAT00000008091.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 54.299 bits (129), Expect = 9.266e-8 Identity = 38/143 (26.57%), Postives = 64/143 (44.76%), Query Frame = 1
Query: 1285 RCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSC---DNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGV-HMNSCEYRVIDCRKCKQKITAIHEQDHN--INLCEMRIVTCEYCQRSIKLNEM 1695
R C C +LR+A QT CG R C CI + + R C N+++ + + F D A RE+ L V C + C++R +L V H+ C++ ++ C + + H C +R V C C + + ++
Sbjct: 2 RFACGSCQGLLRDAVQTHCGHRFCKPCIARLITSVHRSCNDTLMNSNFLVYSPTQFFPDAALRREMGVLPVRCVSEGCEWRGRLLEYDVAHVERCDWVLVPCLLAGCALLLPRAELHRHVAQECSVRPVPCAACAQLLPYRQL 144
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO31690 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX76]) HSP 1 Score: 60.8474 bits (146), Expect = 1.986e-16 Identity = 80/336 (23.81%), Postives = 128/336 (38.10%), Query Frame = 1
Query: 1243 NYDMRLFEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSR-KCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDC--RKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIH-DLKEDLENNKNIIT---ELFSISKSIQELIMKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCK 2229
++ FE +P+ C +C V+ T CG C C ++ CP +Y L N+ DK T R++ L V C C ++ +L+ H+ C + VI C C ++ + H CE +IVTCE+C +P P EE +H +C C F+ I C + + V+H H + I I + K+ NNK I T EL + +++I+EL K + G F+W+I ++ L I+S SFY+ ++GY + K
Sbjct: 11 GFNPEQFETPPSPE-LMCGICLMVVNKPVLTYCGHSFCNFCFNKWRNGKDVVTCPV--DYKQLETNQFMADKKTERQVLSLCVKCMNGPCSWKGELRDKKKHLTKCGHEVIKCVFDGCDTRLARNSMEKHE-ETCEWKIVTCEFCD--------VPY---PKREE-------------------ETVKHRGDCPLAILPCKFSDIGCTFEGR--QHAHVAHCENAVQAHLDMACGTIRDNNKEIRKNNKKIRGNNKEIETLHKELNTANQTIRELKGKMAKL-----------IGTFVWRICDYKDLY--------GEIYSPSFYTSKYGYKVQLK 291 HSP 2 Score: 43.8986 bits (102), Expect = 1.986e-16 Identity = 32/115 (27.83%), Postives = 52/115 (45.22%), Query Frame = 3
Query: 2205 IWLQLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHE-----------NQFVGIQNFLSFTELHSFIF-KDKSIYLKLIV 2513
+ L+ ++ PF G+HLS+ I+ G+YD +L WPF+ I + + + + I P+ P N G+ FLS EL S F KD +++K +V
Sbjct: 288 VQLKANLRTNPFN----GGTHLSLYACIMVGEYDALLEWPFRRKITLYVIDQSDQRKHETLLINPDDVLPDRKKCFHRPITGNNVGYGLTRFLSLEELTSGGFIKDGVMFIKAVV 398
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO48773 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI91]) HSP 1 Score: 65.4698 bits (158), Expect = 7.153e-15 Identity = 80/339 (23.60%), Postives = 132/339 (38.94%), Query Frame = 1
Query: 1264 EFTNAP--DRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLD---LCQFRSKLQSIGVHMNSCEYRVIDC-RKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELF-------------SISKSIQELIMKKFSINAEKC-LQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
EF + P + +C +C LR+ QT CG R C CI+ + KCP DN L+E +L+ D RE+ V C L C ++ L+ + H+ C +C +C + H C R V C++C+ + +++ I HL P + C + Q+ + +H E CP + C+ S + SH + H L + QS+ + D+ ++ F S + I EL K + + L+ +G FIWK++NF + +I S FY+ +GY
Sbjct: 46 EFFDPPLESKYECPICLLGLRDPVQTPCGHRFCFNCIRRSIRDAGPKCP-VDN-TPLSERELYRDNFAKREMMSFIVWCRLKKERGCTWKGALKELEEHLKGCPCMDTNCPNECGAVMQRKEVDKHCAEACPNRSVPCDHCKMKVTISK-IEEHLKGCPCMDTNCPNECG------AVMQRKEVDKHCAEA------CPNRSVPCDHCKMKSSKEQASHGPQEHTPHEAELRREA-LFQSANMQREVDMLGSRGDEYRQFLAYLERKVEDVKTSSDRRIAELTHKLMRLETREIELEGRVCNGTFIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGY 368 HSP 2 Score: 34.2686 bits (77), Expect = 7.153e-15 Identity = 20/66 (30.30%), Postives = 29/66 (43.94%), Query Frame = 3
Query: 2259 GSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSF 2456
G H+S+ ++ GD+D IL WPF I + I + + SR P V N L+F
Sbjct: 384 GEHVSLFIHMMQGDWDGILEWPFIGRITLSILDQSDQIDSR---------RPISETLVAKPNLLAF 440
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO32849 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV3]) HSP 1 Score: 60.4622 bits (145), Expect = 1.580e-13 Identity = 78/344 (22.67%), Postives = 141/344 (40.99%), Query Frame = 1
Query: 1294 CKLCFKVLRNAKQ-TECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFD-DKATVREINQLEVVCPLD--LCQFRSKLQSIGVHMNSCEYRVIDC-RKCKQKITAIHEQDHNINLCEMRIVTCEYC-QRSIKLNE--------MIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQELIMKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY----------NCKCKFIHLGIWI 2253
C +C + + Q ECG R+C C + + KCP C + ++K+ D D+A ++N+L C C+ + H CEY I C C K +Q H C +I++C YC R ++ N+ +IP+ CD ++I ++ + EC K C F + C + S+E + H K+EI + + I + + KE L+N+ E +I K + + + EK ++ IW+IE++ + + + K ++FS +F + + GY + K K H+ +++
Sbjct: 55 CPVCEDIFVSPVQIKECGHRLCQHCYKTIWRSPEPKCPKCSGDL---DDKIPDVDQAFENDMNELPCRCINHEWGCKVEVPFTQMITHKGECEYSDILCDNDCGAKFQRRFKQKHLDKDCPKKIISCPYCDDRHLRENKKEHLEDCLLIPLPC----PNKCDKTLTIPRGQLDEHIEK-------ECPRAKLMCEFESLGCQH--RCSREKMAKHM-KSEI------IGHVKMIFGVVLEQKEKLDNHAQKFEEHETIMKQVDSRVG-----DLEKIAHSQ-----IIWRIEDYTRKLKEAKAGNAETLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFV 365 HSP 2 Score: 34.6538 bits (78), Expect = 1.580e-13 Identity = 25/101 (24.75%), Postives = 47/101 (46.53%), Query Frame = 3
Query: 2256 RGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQ---TIAPE--------IDSP--HENQFVGIQNFLSFTELHSFIF-KDKSIYLKLIVN 2516
+G+H+SV ++ G +D +L WPF + + + ++ R +I P + P +N G F+ E+ S F KD +++LK+ V+
Sbjct: 357 KGTHMSVFVSVLKGAFDALLKWPFHYRVTFFLLNQHENPEERKHVKFSIKPNPIPDNEPFLGRPRLEKNASFGGAKFIKHEEIESGNFIKDDTVFLKVSVD 457
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO45915 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRA4]) HSP 1 Score: 72.7886 bits (177), Expect = 2.084e-13 Identity = 85/372 (22.85%), Postives = 153/372 (41.13%), Query Frame = 1
Query: 1207 LPIFQIIFYIIMNYDMRLFEFTNAPDRCKCKLCFKVLRNAKQ-TECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCP--LDLCQFRSKLQSIGVHMN-SCEYRVIDCRK-CKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSS----------IHDLKEDLENNKNIITEL-----FSISKSIQELIMKKFSINAE--KCLQNEFRSGNFIWKIENFDKLIIKGKMCERF-SIFSKSFYSDEFGYNCKCKFIHLGIWI 2253
+P +++ F + ++ + FE C +C LR+ Q T CG RVC CI+ + +CP DN + LN K+F D A R+I ++++CP D C+++ + + H+ C + C K C + + H C R+V C +C + + +M HL C + CP + C D L+KE L H N+ LLV + ++ ++E L ++ ++ +L IS + L+++K I + +C ++ +G FIWKI+ F + ++ K + S++FY+ GY + G+W+
Sbjct: 1 MPGYEVRFVVPLD---KSFE---------CPVCLMALRDPVQVTPCGHRVCQTCIKPIIRNRRPRCP-LDN-LTLNVGKIFPDNACHRQILSMDILCPHHGDGCEWQGTISDLEKHLERGCNLSEVRCPKDCGASVERGKLEGHYPE-CSRRLVNCTHCNKEVVFADM--------------------------------NVHLQSCASFPISCP---LTCGAKD-LTKEALAVHLNQE----CPLLVIPCRFAEAGCTFKAKRQKMAAHVQESLTSHVAMLCDLVCEQKLQISAQKERLLLQKEHIQLQIVEC-RSRCANGEFIWKIQCFSRKLMDAKTGRASEPMISEAFYTSPHGYK-----MCAGVWL 311
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO37750 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SER6]) HSP 1 Score: 72.7886 bits (177), Expect = 2.891e-13 Identity = 85/372 (22.85%), Postives = 153/372 (41.13%), Query Frame = 1
Query: 1294 CKLCFKVLRNAKQTE-CGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPL--DLCQFRSKLQSIGVHMNSCEYRVIDCR-KCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNE-EMCDDYVSXXXXXXXXXXXXXXXRHLLE-CINKKKKCPFNQINCNT----IDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELF------------SISKSIQELIMKKFSINAEKCLQNE---------------FRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGYNCKCKFIHLGIWIVEAVICLFPLKLLTG 2298
C++C +RNA Q CG R C C+ L +CP DN ++ ++++ D T + I L V+C C+++ +L+ + H+ C++ DC C +I +H C R V C C+ + E + + L NE + D+V+ N + + + RH+ E C+N+ C + CNT D+ + F + N V++IP + +H L D +N I+ F S+ + I+E + + + +E +Q + + +W+I++F + +GK + S FY+ +GY K G E ++LL G
Sbjct: 18 CRICHLPVRNAVQVSVCGHRFCDSCLNHALGETRLRCP-VDN-TAIDYSQVYADDVTNQMIMSLTVICDYYQAGCKWKGQLRKLQGHLAECKFVSADCSNSCGARIQKRRMSEHTSKDCPKRRVCCARCKAEMSY-EQLRVSLRYRNEGALVSDHVTCPRNCGERMRVQDKARHMREDCLNRWVFCQY----CNTEIVFRDRQTHHQSCPSFPLS--CPNNCGVAQIPRGEVELH-LSRDCRSN--IMQCPFRHVGCHKQFPQRSLQRHIEESVQQHLELVSELAIQQQKEINSLKEIVRHCKPYHDSKLLWRIDDFWEAFDEGKRKPGTELHSPVFYTSNYGYKFKVVLFPYGNGSGEGTHLSLYIRLLPG 377
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: ENSORLT00000020861.2 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101167626]) HSP 1 Score: 85.5001 bits (210), Expect = 1.095e-16 Identity = 74/280 (26.43%), Postives = 122/280 (43.57%), Query Frame = 1
Query: 1282 DRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSC-------DNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSI-GVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSX-XXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLK-EDLENNKNIITELFSISKSIQELIMKKFSINAEKCLQN 2091
D+ C C K+LR Q +CG R C C +++G +KC +C + +L + F D A RE+ L VCP + C + ++ H SC++ +I C CK+ + A ++ HN C R + C+YC+ L I H +E+C Y + + + H+ C K C F+ + C+T + KE + H + H LL+ I I+ S+ L+ + LE + EL + + EL M + + LQ
Sbjct: 31 DKHLCNSCEKILRRPLQAQCGHRFCCFCFNRTVSSGPQKCSACIKEDLFEEPTSILKQGGAFHDNAARREVEALAAVCPNEGCTWTGTVKEYEASHEGSCDFTIIMCPSCKELMRANEQERHNERECPERTLNCKYCKEPFLLKN-IKAH-----DEICPKYPMMCEGCAKKKIPREKYVDHIKFCSKFKAPCRFHVVGCDT--SVEKEKIHDHERQCSYEHLNLLLHFIMGIKVSLESLQPQRLEVASQKLHELHQSLRDL-ELRMSQLGRSGTAPLQG 301 HSP 2 Score: 42.3578 bits (98), Expect = 1.485e-7 Identity = 31/111 (27.93%), Postives = 54/111 (48.65%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTEL----------HSFIFKDKSIYLKLIVN 2516
++ ++IY G RG+HLS+ F ++ G D +L WPF + + + + RE P+I S + V N S L +S+I +D++I++K IV+
Sbjct: 457 KMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNRE-HIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYI-RDETIFIKAIVD 565 HSP 3 Score: 34.2686 bits (77), Expect = 1.485e-7 Identity = 14/37 (37.84%), Postives = 21/37 (56.76%), Query Frame = 1
Query: 2104 GNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
G FIWKI +F K ++FS +FY+ ++GY
Sbjct: 420 GIFIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGY 456
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 83.9593 bits (206), Expect = 2.347e-16 Identity = 56/230 (24.35%), Postives = 100/230 (43.48%), Query Frame = 1
Query: 1282 DRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSC-------DNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGV-HMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDY-VSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKI 1944
D+ KC+ C +VLR Q +CG R C C ++ ++G + C +C + +LN ++ F D A REI L C C + ++ H CE+ I C C+ + + HN CE R + C+YC+ + + I H +E+C + + + + H C K CPF+++ C ++ + + H + + + H LL+ +
Sbjct: 26 DKYKCQQCLQVLRKPVQAQCGHRFCVHCFRQLTSSGPKPCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKD-IKAH-----DEICQKFPLQCKDCGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSV--VENGKISEHEHSSTMEHLRLLLPMV 247 HSP 2 Score: 41.9726 bits (97), Expect = 1.189e-7 Identity = 29/110 (26.36%), Postives = 50/110 (45.45%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTEL---------HSFIFKDKSIYLKLIVN 2516
++ +++Y G RG+HLS+ F ++ YD +L WPF + + + + RE P+I S + V N S L S +D +I++K IV+
Sbjct: 404 KMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNRE-HIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVD 512 HSP 3 Score: 34.6538 bits (78), Expect = 1.189e-7 Identity = 27/116 (23.28%), Postives = 56/116 (48.28%), Query Frame = 1
Query: 1879 ENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQELIMKKFSINAEKCLQNEFR----SGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
EN+V N+ E+ ++L +++ H + D E +N+ ++ + +S L +K ++ + + E + G F+WKI +F + ++FS +FYS ++GY
Sbjct: 298 ENIVCVLNR-EVERSSLT------LEAFSHQHRLDQEKIENLSNKIRQLERS---LTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGY 403
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 83.9593 bits (206), Expect = 2.390e-16 Identity = 56/230 (24.35%), Postives = 100/230 (43.48%), Query Frame = 1
Query: 1282 DRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSC-------DNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGV-HMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDY-VSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKI 1944
D+ KC+ C +VLR Q +CG R C C ++ ++G + C +C + +LN ++ F D A REI L C C + ++ H CE+ I C C+ + + HN CE R + C+YC+ + + I H +E+C + + + + H C K CPF+++ C ++ + + H + + + H LL+ +
Sbjct: 33 DKYKCQQCLQVLRKPVQAQCGHRFCVHCFRQLTSSGPKPCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKD-IKAH-----DEICQKFPLQCKDCGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSV--VENGKISEHEHSSTMEHLRLLLPMV 254 HSP 2 Score: 41.9726 bits (97), Expect = 1.258e-7 Identity = 29/110 (26.36%), Postives = 50/110 (45.45%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQNFLSFTEL---------HSFIFKDKSIYLKLIVN 2516
++ +++Y G RG+HLS+ F ++ YD +L WPF + + + + RE P+I S + V N S L S +D +I++K IV+
Sbjct: 411 KMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNRE-HIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVD 519 HSP 3 Score: 34.6538 bits (78), Expect = 1.258e-7 Identity = 27/116 (23.28%), Postives = 56/116 (48.28%), Query Frame = 1
Query: 1879 ENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQELIMKKFSINAEKCLQNEFR----SGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
EN+V N+ E+ ++L +++ H + D E +N+ ++ + +S L +K ++ + + E + G F+WKI +F + ++FS +FYS ++GY
Sbjct: 305 ENIVCVLNR-EVERSSLT------LEAFSHQHRLDQEKIENLSNKIRQLERS---LTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGY 410
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 58.9214 bits (141), Expect = 2.651e-15 Identity = 71/359 (19.78%), Postives = 147/359 (40.95%), Query Frame = 1
Query: 1261 FEFTNAPDR-CKCKLCFKVLRNAKQ-TECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVC--PLDLCQFRSKLQSIGVHMNSCEYRVIDC-RKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLN--PDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPF------------NQINCN----------TIDKLSKENLVSHFNKN-------EIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQELI-----MKKFSINAEKCLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
++F P R +C LC K +R Q + CG R C C+QE+L+ + + +++ D ++I L + C + C++ +++ + H ++C + VI C +C K+T DH + C R V CE+C E H P C++ +++ + + EC + + C + +Q +C +++E+L +H N + + + P + H L++ +++ ++ L +S+ QE++ M++ S++ + G IWK+ ++ + + + K+ FS FY+ +GY
Sbjct: 6 YKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSI---------FFPMGLLPQIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEF-TGEAFENHQGVCPQESVYCENKCG-----ARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCPNQCGTPNIAREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRH-LEDTTKSHLTMMCNL--VSRQRQEILELRREMEELSVSHD---------GVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGY 337 HSP 2 Score: 43.5134 bits (101), Expect = 2.651e-15 Identity = 21/61 (34.43%), Postives = 32/61 (52.46%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIA 2396
+LQ+ + G GSHLSV ++ G+YD +L WPF + + I + LS+ Q I
Sbjct: 338 KLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHIT 398
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:101161132]) HSP 1 Score: 80.1073 bits (196), Expect = 4.797e-15 Identity = 42/126 (33.33%), Postives = 69/126 (54.76%), Query Frame = 1
Query: 1291 KCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYC 1668
+C +C LRNA QT CG R C CI++ + ++CP DN +L+E++LF D REI L V CP C + +L+ + H+ C++ + C +C+Q + + ++H C R ++C C
Sbjct: 77 ECPICLMALRNAIQTRCGHRFCKSCIEKSIRDTGQRCP-VDNE-MLSEDQLFPDNFAKREILSLTVRCPNSDCGEKMELRHLEKHLAQCQFATVPCSQCQQPVRKSYLEEHATVECPRRPMSCPDC 200
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000027149.1 (SMESG000027149.1) HSP 1 Score: 407.527 bits (1046), Expect = 7.661e-136 Identity = 218/227 (96.04%), Postives = 223/227 (98.24%), Query Frame = 1
Query: 1240 MNYDMRLFEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYH 1920
MNYDMRLFEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLA+GSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSICPNNCNQKQQINIKRHLLECINKKKKCPFNQINCNTIDKLSKENL++ K+ IY+
Sbjct: 1 MNYDMRLFEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLASGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSICPNNCNQKQQINIKRHLLECINKKKKCPFNQINCNTIDKLSKENLLA---KSPIYN 224
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000027149.1 (SMESG000027149.1) HSP 1 Score: 398.667 bits (1023), Expect = 1.821e-132 Identity = 214/223 (95.96%), Postives = 219/223 (98.21%), Query Frame = 1
Query: 1252 MRLFEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYH 1920
MRLFEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLA+GSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSICPNNCNQKQQINIKRHLLECINKKKKCPFNQINCNTIDKLSKENL++ K+ IY+
Sbjct: 1 MRLFEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLASGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSICPNNCNQKQQINIKRHLLECINKKKKCPFNQINCNTIDKLSKENLLA---KSPIYN 220
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000027153.1 (SMESG000027153.1) HSP 1 Score: 227.639 bits (579), Expect = 4.011e-70 Identity = 133/336 (39.58%), Postives = 201/336 (59.82%), Query Frame = 1
Query: 1261 FEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPS----CDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISK-----------SIQELIMKKFSINAEKCLQNE---FRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
F F + DR KC LC ++L+NAKQT CGC+ C CI+ YLA G + CPS C+N +L + + D AT +EI L+V CP LC L+++ H+NSCE+R I C KC+ K+ A ++ H+ N CEMR + CEYC + ++ IHLN D E+ C Y +ICPNNC+ ++ +K HL C KK +CPF+ +NCN +DK++KENL+ H N+ + H + L+SKI ++++I +L ++LEN K + EL ++K +I++L K F + ++N+ FR+ FIWK +F+ I + + S+ S FY+ EFGY
Sbjct: 17 FNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCN-VDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQ-AVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGY 350 HSP 2 Score: 58.5362 bits (140), Expect = 4.011e-70 Identity = 35/110 (31.82%), Postives = 55/110 (50.00%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHENQFVGIQN---------FLSFTELHSFIFKDKSIYLKLIVN 2516
++ ++IYP G +G+HLSV F I+ G++D +LSWPFK + + I +E T P+ S + V N LS +S K+ +IYLK+ V+
Sbjct: 351 KMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVD 460
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000027123.1 (SMESG000027123.1) HSP 1 Score: 172.17 bits (435), Expect = 1.943e-53 Identity = 114/340 (33.53%), Postives = 184/340 (54.12%), Query Frame = 1
Query: 1234 IIMNYDMRLFEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPS--CDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITEL----FSISKSIQELIMKKFSINAEK-------CLQNEFRSGNFIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
++ NY + + N KC +C +L+NAKQT+CGC+VC CI EYL+ G + CP+ C N +L + +++D AT +EI L++ CP C + I H+ SCEYR + C C+++I A +Q H CEMRI CE+C +++ + + +HLN E+C +YV CPNNC + +++N+K HL C+N+K + D+ + F+ ++ + L+ +I + + DL LEN II E+ ++++ +L K ++ AE+ N+FR+G+FIWKI++ I + ER SI S FY+ EFGY
Sbjct: 10 LLTNYSL---DIPNLSSSLKCIICSSLLKNAKQTKCGCKVCENCINEYLSKGPKDCPNKECLNELLSIDKDIYNDNATNKEILNLKIACPFKGCAQLETVFKISQHVKSCEYRDVTCDPCQKRILAKEKQKHIDGECEMRITKCEFCHKTMTIKYLNEMHLNTTKNELCSEYVGHCPNNCGETKELNLKLHLETCLNRK-----------SDDQNDTNYHIQEFSNTQLSN---LLKQIALLNQTSKDLLTKLENQDVIIREMSTKYIALTEDNIKLTKKINALEAERSNPVKIIAKTNDFRNGSFIWKIKDLKSQIQNAERSERLSITSDPFYTSEFGY 332 HSP 2 Score: 58.151 bits (139), Expect = 1.943e-53 Identity = 33/110 (30.00%), Postives = 57/110 (51.82%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSP-------HENQFVGIQNFLSFTEL--HSFIFKDKSIYLKLIVN 2516
+L +++YP G +G+HLSV F ++ G+YD +L WPF+ + + + +E T P+ SP N G F S + L +S +K+ +IY+K+ V+
Sbjct: 333 KLCLRVYPSGDGLGKGTHLSVFFALMKGEYDDLLPWPFRQKLTLSLLDQENFTKHYSDTFKPDPKSPCFQRPILDSNIASGSPKFYSISHLSFNSIYYKNDTIYIKITVD 442
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000010523.1 (SMESG000010523.1) HSP 1 Score: 149.828 bits (377), Expect = 1.662e-44 Identity = 107/345 (31.01%), Postives = 169/345 (48.99%), Query Frame = 1
Query: 1237 IMNYDMRLFEFTNAPDRCKCKLCFKVLRNAKQTECGCRVCGQCIQEYLAAGSRKCPSCDNYVLLNENKLFDDKATVREINQLEVVCPLDLCQFRSKLQSIGVHMNSCEYRVIDCRKCKQKITAIHEQDHNINLCEMRIVTCEYCQRSIKLNEMIPIHLNPDNEEMCDDYVSXXXXXXXXXXXXXXXRHLLECINKKKKCPFNQINCNTIDKLSKENLVSHFNKNEIYHNTLLVSKIPYIQSSIHDLKEDLENNKNIITELFSISKSIQEL---IMKKFSINAEKCLQN------EFRSGN----------FIWKIENFDKLIIKGKMCERFSIFSKSFYSDEFGY 2214
IM +R+ + +R KC C ++L A+QT+CGCR+C C E + + KCP CD +E+ DKAT +EIN L V C + C+++ ++ H N CEY I C KC+ IT ++H+ +C R CE+C + + ++ H NP E++CD Y +C NNC++K ++ +K H EC K KCP NC T +L + H +N I H +++ I + + L+ + + K II E+ K+ ++ +KK + EK +Q E + N FIWKI F + + + K + + S YS E GY
Sbjct: 3782 IMKNKIRMV--NDIKERLKCCKCKELLIGARQTKCGCRICTDCTIEVIETQTIKCPGCDETFEEDEDPTTMDKATNKEINNLLVQCRVKECEWKGLMKEAESHTNECEYNEILCEKCQTIITKKTMKEHH-KICIKREEKCEFCGVTDEWIKIEMEHRNPKEEQICDLYEGVCANNCDKKDKVKLKEHWNECSGKPVKCPLELFNCQT--QLPMAEMQKHMMENSIEHTEIMMKTIGMLAWEVKSLRTENDAQKAIIREILESRKNFEKSQGDTLKKM-VEMEKKMQQMTNNIKELETNNSITRKHPTAPFIWKITEFAEKLQRAKDGTQRILDSPPIYSWENGY 4120 HSP 2 Score: 50.447 bits (119), Expect = 1.662e-44 Identity = 31/105 (29.52%), Postives = 54/105 (51.43%), Query Frame = 3
Query: 2214 QLQMQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETRELSRCQTIAPEIDSPHE--NQFVGIQNFLSFTELHSFIF-KDKSIYLKLIVNK 2519
+L +++YP G + G+H+SV + GDYD++L+WPFK N+ + + +E P++ P N +G F L F ++ ++Y+KL V K
Sbjct: 4121 KLGIRLYPNGDGNATGTHISVFIRVGRGDYDELLTWPFKQNMILTMKGQEDYRNPIRTGNEPQMGRPTTDWNTAIGTPRFYPQQRLRGEGFLREDNLYIKLEVEK 4225 The following BLAST results are available for this feature:
BLAST of TNF receptor-associated factor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TNF receptor-associated factor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of TNF receptor-associated factor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008172 ID=SMED30008172|Name=TNF receptor-associated factor|organism=Schmidtea mediterranea sexual|type=transcript|length=2958bpback to top protein sequence of SMED30008172-orf-1 >SMED30008172-orf-1 ID=SMED30008172-orf-1|Name=SMED30008172-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=100bp MQIYPFGYLDCRGSHLSVSFEIINGDYDQILSWPFKHNIQIGIFHRETREback to top protein sequence of SMED30008172-orf-2 >SMED30008172-orf-2 ID=SMED30008172-orf-2|Name=SMED30008172-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=453bp MFFNKIIFLICVYLYSFDLYKLPIFQIIFYIIMNYDMRLFEFTNAPDRCKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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