guanylate cyclase soluble subunit beta-2-like

Overview


Name	guanylate cyclase soluble subunit beta-2-like
Smed ID	SMED30008141
Length (bp)	743

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of guanylate cyclase soluble subunit beta-2-like (SMED30008141) t-SNE clustered cells

Violin plots show distribution of expression levels for guanylate cyclase soluble subunit beta-2-like (SMED30008141) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of guanylate cyclase soluble subunit beta-2-like (SMED30008141) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Homology

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BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Human
Match: NPR1 (natriuretic peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:7943])

HSP 1 Score: 63.1586 bits (152), Expect = 8.749e-11
Identity = 33/93 (35.48%), Postives = 54/93 (58.06%), Query Frame = 3

Query:  465 ITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            + EL++E   R Q    EK+K+E LLYQ++P   A QL++   V+ + F+S +I F++I  F   +A   P ++V  LN ++  FD  I+  D
Sbjct:  827 LEELVEE---RTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFD 916

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Human
Match: GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:4687])

HSP 1 Score: 62.3882 bits (150), Expect = 1.586e-10
Identity = 37/98 (37.76%), Postives = 59/98 (60.20%), Query Frame = 3

Query:  441 KLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTE----IVRFLNLVFNVFD 722
            KL ++L ++T+ +  T+   +  E EKKK++TLLY ++P   AN+LR KRPV  K +++ +ILF+ I  F+ F +     E    IV  LN ++  FD
Sbjct:  386 KLTQELEILTDRLQLTL---RALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD 480

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Human
Match: GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:4687])

HSP 1 Score: 62.003 bits (149), Expect = 1.674e-10
Identity = 37/98 (37.76%), Postives = 59/98 (60.20%), Query Frame = 3

Query:  441 KLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTE----IVRFLNLVFNVFD 722
            KL ++L ++T+ +  T+   +  E EKKK++TLLY ++P   AN+LR KRPV  K +++ +ILF+ I  F+ F +     E    IV  LN ++  FD
Sbjct:  364 KLTQELEILTDRLQLTL---RALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD 458

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Human
Match: GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:4687])

HSP 1 Score: 62.003 bits (149), Expect = 1.686e-10
Identity = 37/98 (37.76%), Postives = 59/98 (60.20%), Query Frame = 3

Query:  441 KLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTE----IVRFLNLVFNVFD 722
            KL ++L ++T+ +  T+   +  E EKKK++TLLY ++P   AN+LR KRPV  K +++ +ILF+ I  F+ F +     E    IV  LN ++  FD
Sbjct:  396 KLTQELEILTDRLQLTL---RALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD 490

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Human
Match: GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:4687])

HSP 1 Score: 62.003 bits (149), Expect = 1.793e-10
Identity = 37/98 (37.76%), Postives = 59/98 (60.20%), Query Frame = 3

Query:  441 KLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTE----IVRFLNLVFNVFD 722
            KL ++L ++T+ +  T+   +  E EKKK++TLLY ++P   AN+LR KRPV  K +++ +ILF+ I  F+ F +     E    IV  LN ++  FD
Sbjct:  296 KLTQELEILTDRLQLTL---RALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD 390

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Celegans
Match: gcy-6 (Receptor-type guanylate cyclase gcy-6 [Source:UniProtKB/Swiss-Prot;Acc:N1NVB7])

HSP 1 Score: 66.6254 bits (161), Expect = 2.444e-12
Identity = 31/90 (34.44%), Postives = 54/90 (60.00%), Query Frame = 3

Query:  474 LIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            L DE   R +    EKKKS+ LLY+M+P + A++L+  + V+P+ F+  ++ F+++ +F        P ++V  LN ++ +FD  IE HD
Sbjct:  845 LEDEVAERMKELVEEKKKSDVLLYRMLPRQVADKLKLGQTVEPETFDIVTLFFSDVVSFTTLAGKCTPLQVVNLLNGLYTIFDGIIEQHD 934

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Celegans
Match: gcy-6 (Receptor-type guanylate cyclase gcy-6 [Source:UniProtKB/Swiss-Prot;Acc:N1NVB7])

HSP 1 Score: 66.6254 bits (161), Expect = 2.465e-12
Identity = 31/90 (34.44%), Postives = 54/90 (60.00%), Query Frame = 3

Query:  474 LIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            L DE   R +    EKKKS+ LLY+M+P + A++L+  + V+P+ F+  ++ F+++ +F        P ++V  LN ++ +FD  IE HD
Sbjct:  841 LEDEVAERMKELVEEKKKSDVLLYRMLPRQVADKLKLGQTVEPETFDIVTLFFSDVVSFTTLAGKCTPLQVVNLLNGLYTIFDGIIEQHD 930

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Celegans
Match: gcy-7 (Receptor-type guanylate cyclase gcy-7 [Source:UniProtKB/Swiss-Prot;Acc:H2L002])

HSP 1 Score: 65.4698 bits (158), Expect = 5.271e-12
Identity = 32/92 (34.78%), Postives = 54/92 (58.70%), Query Frame = 3

Query:  468 TELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            + L +E   R +    EKKKS+ LLY+M+P   A++L+  + V+P+ FE  +I F+++  F    +   P ++V  LN ++ +FD  IE HD
Sbjct:  845 SSLEEEVSERTKELVEEKKKSDVLLYRMLPKTVADKLKLGQTVEPETFEQVTIFFSDVVQFTTLASKCTPLQVVNLLNDLYTIFDGIIEKHD 936

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Celegans
Match: gcy-7 (Receptor-type guanylate cyclase gcy-7 [Source:UniProtKB/Swiss-Prot;Acc:H2L002])

HSP 1 Score: 65.4698 bits (158), Expect = 5.942e-12
Identity = 32/92 (34.78%), Postives = 54/92 (58.70%), Query Frame = 3

Query:  468 TELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            + L +E   R +    EKKKS+ LLY+M+P   A++L+  + V+P+ FE  +I F+++  F    +   P ++V  LN ++ +FD  IE HD
Sbjct:  845 SSLEEEVSERTKELVEEKKKSDVLLYRMLPKTVADKLKLGQTVEPETFEQVTIFFSDVVQFTTLASKCTPLQVVNLLNDLYTIFDGIIEKHD 936

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Celegans
Match: gcy-22 (Receptor-type guanylate cyclase gcy-22 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTY1])

HSP 1 Score: 65.0846 bits (157), Expect = 8.329e-12
Identity = 31/92 (33.70%), Postives = 54/92 (58.70%), Query Frame = 3

Query:  468 TELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            + L DE   R +    EKK+S+ LLY+M+P + A +L+  + V+P+ F+  +I F+++ +F    +   P ++V  LN ++  FD  IE HD
Sbjct:  816 SNLEDEVQARMKELTEEKKRSDVLLYRMLPKQVAEKLKLGQSVEPETFDCVTIFFSDVVSFTTLASRCTPLQVVNLLNDLYTTFDAIIEQHD 907

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Fly
Match: CG33958 (gene:FBgn0053958 transcript:FBtr0099994)

HSP 1 Score: 71.2478 bits (173), Expect = 6.544e-14
Identity = 33/76 (43.42%), Postives = 51/76 (67.11%), Query Frame = 3

Query:  516 EKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            EK+KS++LL+QM+P   A QL+Q + V  +L+E+ +I F++I  F    A   P E+V FLN ++ VFD+ IE +D
Sbjct:  459 EKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYD 534

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Fly
Match: Gycbeta100B (gene:FBgn0013973 transcript:FBtr0085753)

HSP 1 Score: 64.6994 bits (156), Expect = 1.241e-11
Identity = 34/100 (34.00%), Postives = 61/100 (61.00%), Query Frame = 3

Query:  435 QRKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLP----PTEIVRFLNLVFNVFD 722
            + KL + L ++T+ + +T    +  E+EK+K++ LLY ++P   AN+LR +RPV PK ++S +++F+ I  F  + A         +IV+ LN ++ VFD
Sbjct:  472 EYKLTKNLEMLTDKLQQTF---RDLESEKQKTDRLLYSVLPKSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYTVFD 568

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Fly
Match: CG31183 (gene:FBgn0051183 transcript:FBtr0346151)

HSP 1 Score: 63.5438 bits (153), Expect = 3.500e-11
Identity = 35/93 (37.63%), Postives = 53/93 (56.99%), Query Frame = 3

Query:  465 ITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            + EL++E   R Q    EKKK E LLYQ++P   A QL   +PV  + F+  +I F++I  F   +A   P ++V+FLN ++  FD  +E  D
Sbjct:  904 LEELVEE---RTQDYHEEKKKCEKLLYQLLPQSVAAQLISGQPVVAETFDQVTIYFSDIVGFTAISAESTPMQVVQFLNDLYTCFDSIVENFD 993

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Fly
Match: CG31183 (gene:FBgn0051183 transcript:FBtr0083187)

HSP 1 Score: 63.5438 bits (153), Expect = 3.500e-11
Identity = 35/93 (37.63%), Postives = 53/93 (56.99%), Query Frame = 3

Query:  465 ITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            + EL++E   R Q    EKKK E LLYQ++P   A QL   +PV  + F+  +I F++I  F   +A   P ++V+FLN ++  FD  +E  D
Sbjct:  904 LEELVEE---RTQDYHEEKKKCEKLLYQLLPQSVAAQLISGQPVVAETFDQVTIYFSDIVGFTAISAESTPMQVVQFLNDLYTCFDSIVENFD 993

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Fly
Match: CG10738 (gene:FBgn0036368 transcript:FBtr0304792)

HSP 1 Score: 62.3882 bits (150), Expect = 8.304e-11
Identity = 32/90 (35.56%), Postives = 53/90 (58.89%), Query Frame = 3

Query:  474 LIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            L+D+   R    + EKKK++ LL++M+P   A+QL++   V P+ +E  SI F++I  F   +A   P ++V FLN ++  FD  I  +D
Sbjct:  861 LVDD---RTDQLQEEKKKTDALLHEMLPRCVADQLKKGHKVDPEHYEQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYD 947

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Zebrafish
Match: gucy1b2 (guanylate cyclase 1, soluble, beta 2 [Source:ZFIN;Acc:ZDB-GENE-130530-664])

HSP 1 Score: 66.6254 bits (161), Expect = 3.160e-12
Identity = 33/88 (37.50%), Postives = 53/88 (60.23%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            +E  I  ++ E EK+KSE LLY M+P   ANQL++ + V+   F+ C+ILF+++  F    A   P +IV  LN +++ FD    +H+
Sbjct:  421 EELRILSRNLEIEKQKSEKLLYAMLPTHVANQLKEGKRVEAGEFKVCTILFSDVVTFTNICAACEPIQIVNMLNAMYSRFDRLTSIHN 508

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Zebrafish
Match: gucy2d (guanylate cyclase 2D, retinal [Source:ZFIN;Acc:ZDB-GENE-011128-9])

HSP 1 Score: 66.2402 bits (160), Expect = 4.556e-12
Identity = 35/102 (34.31%), Postives = 58/102 (56.86%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E E++K++ LL QM+P   A  L+  +PVKP+ F   ++ F++I  F   +A+  P E+V  LN ++  FD  I +HD
Sbjct:  856 RMLEQYSSNLEDLIRE---RTEELEVERQKTDALLAQMLPKSVALALKTGKPVKPEHFAEVTLYFSDIVGFTTISALSEPIEVVDLLNDLYTHFDGIIAIHD 954

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Zebrafish
Match: gucy2d (guanylate cyclase 2D, retinal [Source:ZFIN;Acc:ZDB-GENE-011128-9])

HSP 1 Score: 66.2402 bits (160), Expect = 4.581e-12
Identity = 35/102 (34.31%), Postives = 58/102 (56.86%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E E++K++ LL QM+P   A  L+  +PVKP+ F   ++ F++I  F   +A+  P E+V  LN ++  FD  I +HD
Sbjct:  895 RMLEQYSSNLEDLIRE---RTEELEVERQKTDALLAQMLPKSVALALKTGKPVKPEHFAEVTLYFSDIVGFTTISALSEPIEVVDLLNDLYTHFDGIIAIHD 993

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Zebrafish
Match: gucy2d (guanylate cyclase 2D, retinal [Source:ZFIN;Acc:ZDB-GENE-011128-9])

HSP 1 Score: 66.2402 bits (160), Expect = 4.641e-12
Identity = 35/102 (34.31%), Postives = 58/102 (56.86%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E E++K++ LL QM+P   A  L+  +PVKP+ F   ++ F++I  F   +A+  P E+V  LN ++  FD  I +HD
Sbjct:  854 RMLEQYSSNLEDLIRE---RTEELEVERQKTDALLAQMLPKSVALALKTGKPVKPEHFAEVTLYFSDIVGFTTISALSEPIEVVDLLNDLYTHFDGIIAIHD 952

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Zebrafish
Match: gucy2d (guanylate cyclase 2D, retinal [Source:ZFIN;Acc:ZDB-GENE-011128-9])

HSP 1 Score: 66.2402 bits (160), Expect = 4.807e-12
Identity = 35/102 (34.31%), Postives = 58/102 (56.86%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E E++K++ LL QM+P   A  L+  +PVKP+ F   ++ F++I  F   +A+  P E+V  LN ++  FD  I +HD
Sbjct:  841 RMLEQYSSNLEDLIRE---RTEELEVERQKTDALLAQMLPKSVALALKTGKPVKPEHFAEVTLYFSDIVGFTTISALSEPIEVVDLLNDLYTHFDGIIAIHD 939

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Xenopus
Match: ank1 (ankyrin 1 [Source:Xenbase;Acc:XB-GENE-5838516])

HSP 1 Score: 66.6254 bits (161), Expect = 4.223e-12
Identity = 35/88 (39.77%), Postives = 52/88 (59.09%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            +E  I  +H E EKKK+E LLY M+P   ANQL++ + V+   F+ C+ILF+++  F    A   P +IV  LN ++  FD    +HD
Sbjct:  341 EELRILSKHLEEEKKKTELLLYAMLPKHVANQLKEGKRVEAGEFKECTILFSDVVTFTNICAQCEPIQIVFMLNSMYLRFDRLTTVHD 428

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Xenopus
Match: slc8a3 (solute carrier family 8 (sodium/calcium exchanger), member 3 [Source:Xenbase;Acc:XB-GENE-954537])

HSP 1 Score: 66.6254 bits (161), Expect = 4.899e-12
Identity = 35/102 (34.31%), Postives = 58/102 (56.86%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E EK+K++ LL QM+P   A  L+   PV+P+ F+  +I F++I  F   +++  P E+V  LN ++ +FD  I  HD
Sbjct:  780 RMLEQYSSNLEDLIRE---RTEELEVEKQKTDKLLTQMLPPSVAEALKTGTPVEPEYFDEVTIYFSDIVGFTTISSLSDPIEVVDLLNDLYTLFDAIIGSHD 878

[Close]

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E EK+K++ LL QM+P   A  L+   PV+P+ F+  +I F++I  F   +++  P E+V  LN ++ +FD  I  HD
Sbjct:  763 RMLEQYSSNLEDLIRE---RTEELEVEKQKTDKLLTQMLPPSVAEALKTGTPVEPEYFDEVTIYFSDIVGFTTISSLSDPIEVVDLLNDLYTLFDAIIGSHD 861

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Xenopus
Match: slc8a3 (solute carrier family 8 (sodium/calcium exchanger), member 3 [Source:Xenbase;Acc:XB-GENE-954537])

HSP 1 Score: 66.6254 bits (161), Expect = 5.340e-12
Identity = 35/102 (34.31%), Postives = 58/102 (56.86%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E EK+K++ LL QM+P   A  L+   PV+P+ F+  +I F++I  F   +++  P E+V  LN ++ +FD  I  HD
Sbjct:  794 RMLEQYSSNLEDLIRE---RTEELEVEKQKTDKLLTQMLPPSVAEALKTGTPVEPEYFDEVTIYFSDIVGFTTISSLSDPIEVVDLLNDLYTLFDAIIGSHD 892

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Xenopus
Match: slc8a3 (solute carrier family 8 (sodium/calcium exchanger), member 3 [Source:Xenbase;Acc:XB-GENE-954537])

HSP 1 Score: 66.6254 bits (161), Expect = 5.508e-12
Identity = 35/102 (34.31%), Postives = 58/102 (56.86%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E EK+K++ LL QM+P   A  L+   PV+P+ F+  +I F++I  F   +++  P E+V  LN ++ +FD  I  HD
Sbjct:  788 RMLEQYSSNLEDLIRE---RTEELEVEKQKTDKLLTQMLPPSVAEALKTGTPVEPEYFDEVTIYFSDIVGFTTISSLSDPIEVVDLLNDLYTLFDAIIGSHD 886

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Mouse
Match: Gucy1b2 (guanylate cyclase 1, soluble, beta 2 [Source:MGI Symbol;Acc:MGI:2660873])

HSP 1 Score: 74.3294 bits (181), Expect = 1.132e-14
Identity = 35/88 (39.77%), Postives = 52/88 (59.09%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            +E  +   H   EKKK+ETLLY M+P   ANQL++ + V    FE+C+ILF+++  F    A   P +IV  LN +++ FD    +HD
Sbjct:  487 EELRVLSNHLAIEKKKTETLLYAMLPEHVANQLKEGKKVAAGEFETCTILFSDVVTFTNICAACEPIQIVNMLNSMYSKFDRLTNIHD 574

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Mouse
Match: Gucy1b2 (guanylate cyclase 1, soluble, beta 2 [Source:MGI Symbol;Acc:MGI:2660873])

HSP 1 Score: 73.9442 bits (180), Expect = 1.373e-14
Identity = 35/88 (39.77%), Postives = 52/88 (59.09%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            +E  +   H   EKKK+ETLLY M+P   ANQL++ + V    FE+C+ILF+++  F    A   P +IV  LN +++ FD    +HD
Sbjct:  502 EELRVLSNHLAIEKKKTETLLYAMLPEHVANQLKEGKKVAAGEFETCTILFSDVVTFTNICAACEPIQIVNMLNSMYSKFDRLTNIHD 589

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Mouse
Match: Gucy2e (guanylate cyclase 2e [Source:MGI Symbol;Acc:MGI:105123])

HSP 1 Score: 65.0846 bits (157), Expect = 1.291e-11
Identity = 35/102 (34.31%), Postives = 57/102 (55.88%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E EK+K++ LL QM+P   A  L+    V+P+ FE  ++ F++I  F   +A+  P E+V  LN ++ +FD  I  HD
Sbjct:  825 RMLEQYSSNLEDLIRE---RTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGAHD 923

[Close]

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E EK+K++ LL QM+P   A  L+    V+P+ FE  ++ F++I  F   +A+  P E+V  LN ++ +FD  I  HD
Sbjct:  825 RMLEQYSSNLEDLIRE---RTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGAHD 923

[Close]

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E EK+K++ LL QM+P   A  L+    V+P+ FE  ++ F++I  F   +A+  P E+V  LN ++ +FD  I  HD
Sbjct:  825 RMLEQYSSNLEDLIRE---RTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGAHD 923

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. UniProt/SwissProt
Match: sp|P22717|GCYB2_RAT (Guanylate cyclase soluble subunit beta-2 OS=Rattus norvegicus OX=10116 GN=Gucy1b2 PE=2 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 1.028e-13
Identity = 36/88 (40.91%), Postives = 52/88 (59.09%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            +E  +   H   EKKK+ETLLY M+P   ANQL++ R V    FE+C+ILF+++  F    A   P +IV  LN +++ FD    +HD
Sbjct:  361 EELRVLSNHLAIEKKKTETLLYAMLPEHVANQLKEGRKVAAGEFETCTILFSDVVTFTNICAACEPIQIVNMLNSMYSKFDRLTSVHD 448

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. UniProt/SwissProt
Match: sp|O75343|GCYB2_HUMAN (Guanylate cyclase soluble subunit beta-2 OS=Homo sapiens OX=9606 GN=GUCY1B2 PE=5 SV=2)

HSP 1 Score: 69.707 bits (169), Expect = 2.372e-12
Identity = 34/87 (39.08%), Postives = 51/87 (58.62%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELH 740
            +E  +  +H   EKKK+ETLLY M+P   ANQLR+ + V    F+SC+ILF+++  F        P +IV  LN +++ FD    +H
Sbjct:  344 EELQVLSKHLAIEKKKTETLLYAMLPKHVANQLREGKKVAAGEFKSCTILFSDVVTFTNICTACEPIQIVNVLNSMYSKFDRLTSVH 430

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. UniProt/SwissProt
Match: sp|N1NVB7|GCY6_CAEEL (Receptor-type guanylate cyclase gcy-6 OS=Caenorhabditis elegans OX=6239 GN=gcy-6 PE=2 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 3.109e-11
Identity = 31/90 (34.44%), Postives = 54/90 (60.00%), Query Frame = 3

Query:  474 LIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            L DE   R +    EKKKS+ LLY+M+P + A++L+  + V+P+ F+  ++ F+++ +F        P ++V  LN ++ +FD  IE HD
Sbjct:  845 LEDEVAERMKELVEEKKKSDVLLYRMLPRQVADKLKLGQTVEPETFDIVTLFFSDVVSFTTLAGKCTPLQVVNLLNGLYTIFDGIIEQHD 934

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. UniProt/SwissProt
Match: sp|H2L002|GCY7_CAEEL (Receptor-type guanylate cyclase gcy-7 OS=Caenorhabditis elegans OX=6239 GN=gcy-7 PE=2 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 6.705e-11
Identity = 32/92 (34.78%), Postives = 54/92 (58.70%), Query Frame = 3

Query:  468 TELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            + L +E   R +    EKKKS+ LLY+M+P   A++L+  + V+P+ FE  +I F+++  F    +   P ++V  LN ++ +FD  IE HD
Sbjct:  845 SSLEEEVSERTKELVEEKKKSDVLLYRMLPKTVADKLKLGQTVEPETFEQVTIFFSDVVQFTTLASKCTPLQVVNLLNDLYTIFDGIIEKHD 936

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. UniProt/SwissProt
Match: sp|P52785|GUC2E_MOUSE (Retinal guanylyl cyclase 1 OS=Mus musculus OX=10090 GN=Gucy2e PE=1 SV=2)

HSP 1 Score: 65.0846 bits (157), Expect = 9.030e-11
Identity = 35/102 (34.31%), Postives = 57/102 (55.88%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E EK+K++ LL QM+P   A  L+    V+P+ FE  ++ F++I  F   +A+  P E+V  LN ++ +FD  I  HD
Sbjct:  825 RMLEQYSSNLEDLIRE---RTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGAHD 923

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. TrEMBL
Match: G3PRL3 (Guanylate cyclase 1, soluble, beta 2 OS=Gasterosteus aculeatus OX=69293 PE=3 SV=1)

HSP 1 Score: 80.1073 bits (196), Expect = 1.783e-13
Identity = 40/88 (45.45%), Postives = 53/88 (60.23%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            +E  I  QH ETEK+K+ETLLY M+P   ANQL+  R VK   FE C+ILF+++  F    A   P  IV  LN +++ FD    +HD
Sbjct:  418 EELRILSQHLETEKEKTETLLYAMLPRHIANQLKDGRSVKAGEFEVCTILFSDVVTFTSICAACEPIHIVHMLNSMYSKFDRLTSIHD 505

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. TrEMBL
Match: R7UFR9 (Guanylate cyclase domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_166290 PE=3 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 2.346e-12
Identity = 33/76 (43.42%), Postives = 55/76 (72.37%), Query Frame = 3

Query:  516 EKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            EKK++++LLYQM+P + A+QL++++ V  + F+  +I F++I  F  FTA L P ++VR LN +F +FD+ IE +D
Sbjct:  342 EKKRTDSLLYQMMPRQVADQLKRRKGVTAEYFKEVTIFFSDIVGFTRFTAELTPMQVVRVLNEIFTLFDERIEQYD 417

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. TrEMBL
Match: A0A0F8ARX1 (Guanylate cyclase soluble subunit beta-2 OS=Larimichthys crocea OX=215358 GN=EH28_04318 PE=3 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 3.158e-12
Identity = 38/88 (43.18%), Postives = 52/88 (59.09%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            +E  I  QH E EK+K+ETLLY M+P   ANQL+  + VK   FE C+ILF+++  F    A   P  IV  LN +++ FD    +HD
Sbjct:  318 EELRILSQHLEAEKEKTETLLYAMLPRHIANQLKDGKSVKAGDFEVCTILFSDVVTFTNICAACEPIHIVHMLNSMYSKFDRLTNIHD 405

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. TrEMBL
Match: A0A3Q1IDN3 (Guanylate cyclase 1, soluble, beta 2 OS=Anabas testudineus OX=64144 PE=3 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 3.394e-12
Identity = 37/88 (42.05%), Postives = 54/88 (61.36%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            +E  I  +H E EK+K+ETLLY M+P   ANQL+  + V+   FE C+ILF+++  F    A   P +IV  LNL+++ FD    +HD
Sbjct:  392 EELRILSRHLEAEKEKTETLLYAMLPRHIANQLKDGKSVQAGEFEVCTILFSDVVTFTNICAACEPIDIVHMLNLMYSKFDRLTNVHD 479

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. TrEMBL
Match: A0A0F8AVG5 (Guanylate cyclase soluble subunit beta-2 OS=Larimichthys crocea OX=215358 GN=EH28_08350 PE=3 SV=1)

HSP 1 Score: 76.2554 bits (186), Expect = 3.957e-12
Identity = 38/88 (43.18%), Postives = 52/88 (59.09%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            +E  I  QH E EK+K+ETLLY M+P   ANQL+  + VK   FE C+ILF+++  F    A   P  IV  LN +++ FD    +HD
Sbjct:  289 EELRILSQHLEAEKEKTETLLYAMLPRHIANQLKDGKSVKAGDFEVCTILFSDVVTFTNICAACEPIHIVHMLNSMYSKFDRLTNIHD 376

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Cavefish
Match: gucy1b2 (guanylate cyclase 1, soluble, beta 2 [Source:ZFIN;Acc:ZDB-GENE-130530-664])

HSP 1 Score: 70.0922 bits (170), Expect = 2.137e-13
Identity = 35/88 (39.77%), Postives = 53/88 (60.23%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            +E  I  ++ E EKKK+ETLLY M+P   ANQL++ + V    F+ C+ILF+++  F    A   P +IV  LN +++ FD    +HD
Sbjct:  390 EELRILSRNLEVEKKKTETLLYAMLPRHVANQLKEGKKVDAGEFKVCTILFSDVVTFTNICAACEPIQIVHMLNSMYSRFDRLTNVHD 477

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Cavefish
Match: gucy1b2 (guanylate cyclase 1, soluble, beta 2 [Source:ZFIN;Acc:ZDB-GENE-130530-664])

HSP 1 Score: 70.0922 bits (170), Expect = 2.234e-13
Identity = 35/88 (39.77%), Postives = 53/88 (60.23%), Query Frame = 3

Query:  480 DETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            +E  I  ++ E EKKK+ETLLY M+P   ANQL++ + V    F+ C+ILF+++  F    A   P +IV  LN +++ FD    +HD
Sbjct:  384 EELRILSRNLEVEKKKTETLLYAMLPRHVANQLKEGKKVDAGEFKVCTILFSDVVTFTNICAACEPIQIVHMLNSMYSRFDRLTNVHD 471

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Cavefish
Match: ENSAMXT00000016107.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001112.1:50819:73979:1 gene:ENSAMXG00000015515.2 transcript:ENSAMXT00000016107.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.1662 bits (165), Expect = 1.047e-12
Identity = 30/83 (36.14%), Postives = 51/83 (61.45%), Query Frame = 3

Query:  495 RKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R Q    EK+K++ LLY M+P + A+ LRQ +P + + + S ++ F++I  F   ++   P ++V FLN ++  FDD I+ HD
Sbjct:  600 RTQDLMHEKQKTDRLLYSMLPKQVADDLRQGKPSQAQSYVSATVFFSDIVGFTQLSSTSTPYQVVDFLNKLYTTFDDIIDNHD 682

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Cavefish
Match: gc2 (retinal guanylyl cyclase 2 [Source:NCBI gene;Acc:103025043])

HSP 1 Score: 65.4698 bits (158), Expect = 7.757e-12
Identity = 37/102 (36.27%), Postives = 57/102 (55.88%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + ELI E   R +  E EK+K+E LL QM+P   A  L+    V+P+ +E  +I F++I  F   +A   P E+V  LN +++ FD+ I  HD
Sbjct:  833 RMLEQYSSNLEELIRE---RTEELEVEKQKTEKLLTQMLPPSVAEALKLGTTVEPEYYECVTIYFSDIVGFTTISANSEPIEVVDLLNDLYSTFDEIIANHD 931

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Cavefish
Match: ENSAMXT00000020840.2 (retinal guanylyl cyclase 2 [Source:NCBI gene;Acc:103026799])

HSP 1 Score: 65.0846 bits (157), Expect = 1.241e-11
Identity = 38/102 (37.25%), Postives = 57/102 (55.88%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + ELI E   R +  E EK+K+E LL QM+P   A  L+    V+P+ F+S S+ F++I  F   +A   P E+V  LN ++ +FD  I  HD
Sbjct:  809 RMLEQYSSNLEELIRE---RTEELEIEKQKTEKLLTQMLPPSVAEALKVGGTVEPEYFDSVSLYFSDIVGFTTISANSEPIEVVDLLNDLYTLFDAIIGNHD 907

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Sea Lamprey
Match: gucy1b2 (guanylate cyclase 1, soluble, beta 2 [Source:ZFIN;Acc:ZDB-GENE-130530-664])

HSP 1 Score: 65.855 bits (159), Expect = 6.873e-13
Identity = 31/78 (39.74%), Postives = 48/78 (61.54%), Query Frame = 3

Query:  510 ETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            + EKKK+E LLY M+P   ANQL++ + V+   F+ C+ILF+++  F    AV  P +IV  LN ++  FD    +H+
Sbjct:  149 QVEKKKTEALLYAMLPHHVANQLKEGKKVEAGEFKVCTILFSDVVTFTNICAVCEPIQIVHMLNAMYMRFDRLTTVHN 226

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006352.1 (pep scaffold:Pmarinus_7.0:GL477176:19246:83539:-1 gene:ENSPMAG00000005587.1 transcript:ENSPMAT00000006352.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.6178 bits (148), Expect = 2.800e-11
Identity = 34/93 (36.56%), Postives = 55/93 (59.14%), Query Frame = 3

Query:  465 ITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            + EL++E   R Q    EK+K+ETLLYQ++P   A QL++   V+ + F+S +I F++I  F   +A   P ++V  LN ++  FD  I+  D
Sbjct:  593 LEELVEE---RTQAYLEEKRKAETLLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSLSAESTPMQVVTLLNDLYTCFDAIIDNFD 682

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002650.1 (pep scaffold:Pmarinus_7.0:GL478983:4063:28109:1 gene:ENSPMAG00000002416.1 transcript:ENSPMAT00000002650.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.077 bits (144), Expect = 9.417e-11
Identity = 30/89 (33.71%), Postives = 55/89 (61.80%), Query Frame = 3

Query:  483 ETIIRKQHQET--EKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            E+++ ++ Q+   EK+K++ LLY M+P + A+ LRQ R  K + + S ++ F++I  F   ++   P E+V FLN ++  FD  I+ +D
Sbjct:  271 ESVVTERTQDLVLEKQKTDRLLYSMLPKQIADDLRQGRVTKAQSYASATVFFSDIVGFTQLSSSSTPYEVVDFLNKLYTSFDGIIDNYD 359

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Sea Lamprey
Match: NPR1 (natriuretic peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:7943])

HSP 1 Score: 58.5362 bits (140), Expect = 2.594e-10
Identity = 32/90 (35.56%), Postives = 51/90 (56.67%), Query Frame = 3

Query:  465 ITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIE 734
            + EL++E   R Q    EK K+E LLYQ++P   A QL++   V  + F+S +I  ++I  F   +A   P ++V FLN ++  FD  I+
Sbjct:  276 LEELVEE---RTQAYLEEKGKAEALLYQILPHSVAEQLKRGETVPAEAFDSVTIYLSDIVGFTAMSAQSTPMQVVAFLNDLYTCFDAIID 362

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000043.1 (pep scaffold:Pmarinus_7.0:GL480785:4349:14716:1 gene:ENSPMAG00000000040.1 transcript:ENSPMAT00000000043.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.2174 bits (121), Expect = 7.392e-8
Identity = 29/102 (28.43%), Postives = 53/102 (51.96%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R+L +    +  L++E   R +  + E+ +++ L YQ++P      L+    V+P+LFE  +I F++I  F        P E+V  LN ++  FD  ++ HD
Sbjct:  214 RRLEQYSKNLERLVEE---RTELYKRERDRADHLNYQLLPKTVVQALKSVGSVQPELFEEVTIYFSDIVGFTTICKHCEPMEVVCLLNDLYKEFDSIVDSHD 312

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Nematostella
Match: EDO44983 (Guanylate cyclase [Source:UniProtKB/TrEMBL;Acc:A7RUA8])

HSP 1 Score: 62.003 bits (149), Expect = 2.795e-11
Identity = 28/83 (33.73%), Postives = 52/83 (62.65%), Query Frame = 3

Query:  495 RKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R +  ETEK K++ LLY+M+P   A+QL+   P+K + F   ++ + +I +F   TA+  P ++++ LN V+++FD  +  +D
Sbjct:  235 RTRQLETEKSKTDELLYRMLPRLIADQLKAGLPLKAESFSEVTVFYCDIVDFTVITALSEPMQVIKLLNDVYSLFDTIMGRYD 317

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Nematostella
Match: EDO36204 (Guanylate cyclase [Source:UniProtKB/TrEMBL;Acc:A7SJA3])

HSP 1 Score: 60.8474 bits (146), Expect = 8.424e-11
Identity = 28/83 (33.73%), Postives = 51/83 (61.45%), Query Frame = 3

Query:  495 RKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R +  E EK K++ LLY+M+P   A+QL+  + V+ +LF+  ++ F++I  F   ++   P ++V FLN ++  FD+ I  +D
Sbjct:  247 RTRQLEAEKAKTDQLLYEMLPRPVADQLKSGKSVEAELFDQVTVFFSDIVGFTKLSSSSTPIQVVTFLNDLYTYFDNIIPNYD 329

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Nematostella
Match: EDO27923 (Guanylate cyclase [Source:UniProtKB/TrEMBL;Acc:A7T7X3])

HSP 1 Score: 59.6918 bits (143), Expect = 2.034e-10
Identity = 28/83 (33.73%), Postives = 48/83 (57.83%), Query Frame = 3

Query:  495 RKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R +    EK K++ LLY+M+P   A++L++  PV  + F+S +I F++I  F    A   P ++V  LN ++  FD  ++ HD
Sbjct:  222 RTKQLAEEKAKTDELLYKMLPRPIADELKKGNPVSAESFQSVTIFFSDIVGFTSVAAQSTPLQVVDLLNQLYTRFDKVVDEHD 304

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Nematostella
Match: EDO36203 (Guanylate cyclase [Source:UniProtKB/TrEMBL;Acc:A7SJA1])

HSP 1 Score: 57.7658 bits (138), Expect = 9.031e-10
Identity = 31/89 (34.83%), Postives = 49/89 (55.06%), Query Frame = 3

Query:  483 ETII--RKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            ETI+  R +    EK K++ LLY+M+P   A  L++  PV  + + S +I F++I  F    A   P ++V  LN ++  FD  I+ HD
Sbjct:  337 ETIVDERTRQLADEKAKTDELLYKMLPRYIAESLKRGEPVIAESYSSVTIFFSDIVGFTELAAASTPLQVVDLLNDLYTCFDTIIDKHD 425

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Nematostella
Match: EDO47084 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN70])

HSP 1 Score: 56.9954 bits (136), Expect = 1.550e-9
Identity = 31/95 (32.63%), Postives = 56/95 (58.95%), Query Frame = 3

Query:  441 KLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNF-DFFTAVLPPTEIVRFLNLVFNVFD 722
            KL ++L ++T+ + +T    +  E E++ ++ LLY ++P   AN LR ++PV    +E  +I+F+ I +F ++   +  P EIV  LN V+  FD
Sbjct:  375 KLSQRLEILTDKLQQT---SRELENEQQLNDRLLYSILPASVANDLRLRKPVNANKYEIVTIMFSGIVDFTNYCNKIKEPMEIVEMLNEVYTEFD 466

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Medaka
Match: olgc3 (membrane guanylyl cyclase [Source:NCBI gene;Acc:100192404])

HSP 1 Score: 67.0106 bits (162), Expect = 2.478e-12
Identity = 33/102 (32.35%), Postives = 58/102 (56.86%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R    E E+ K+E L+ Q++P   A  L++ +PV+P+ +  C++ F++I  F   +A+  P E+V  LN ++ +FD  I  HD
Sbjct:  778 RMLEQYSSNLEDLIRE---RTDELEVERNKTEKLVGQLLPKSVAQALKKGKPVQPEHYSDCTLYFSDIVGFTTISALSEPIEVVDLLNDLYTMFDAIIASHD 876

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Medaka
Match: olgc3 (membrane guanylyl cyclase [Source:NCBI gene;Acc:100192404])

HSP 1 Score: 67.0106 bits (162), Expect = 2.490e-12
Identity = 33/102 (32.35%), Postives = 58/102 (56.86%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R    E E+ K+E L+ Q++P   A  L++ +PV+P+ +  C++ F++I  F   +A+  P E+V  LN ++ +FD  I  HD
Sbjct:  778 RMLEQYSSNLEDLIRE---RTDELEVERNKTEKLVGQLLPKSVAQALKKGKPVQPEHYSDCTLYFSDIVGFTTISALSEPIEVVDLLNDLYTMFDAIIASHD 876

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Medaka
Match: olgc-r2 (guanylate cyclase OlGC-R2 [Source:NCBI gene;Acc:100216004])

HSP 1 Score: 65.855 bits (159), Expect = 5.885e-12
Identity = 39/102 (38.24%), Postives = 56/102 (54.90%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + ELI E   R +  E EK+K+E LL QM+P   A  L     VKP+ F+S S+ F++I  F   +A   P E+V  LN ++ +FD  I  HD
Sbjct:  833 RMLEQYSSNLEELIRE---RTEELEIEKQKTEKLLTQMLPPSVAEALMVGGTVKPEYFDSVSLYFSDIVGFTTISANSEPIEVVDLLNDLYTLFDAIIGNHD 931

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Medaka
Match: olgc5 (guanylate cyclase OlGC5 [Source:NCBI gene;Acc:100125800])

HSP 1 Score: 65.855 bits (159), Expect = 6.919e-12
Identity = 33/102 (32.35%), Postives = 59/102 (57.84%), Query Frame = 3

Query:  438 RKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R L +  + + +LI E   R +  E E++K++ L+ QM+P   A  L+  +PV+P+ F   ++ F++I  F   + +  P E+V  LN ++++FD  I LHD
Sbjct:  873 RMLEQYSSNLEDLIRE---RTEELEVERQKTDNLVAQMLPKSVAQSLKLGKPVEPEHFSEVTLYFSDIVGFSTISTLSEPIEVVDLLNDLYSLFDAIIPLHD 971

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Medaka
Match: olgc2 (membrane guanylyl cyclase [Source:NCBI gene;Acc:100125799])

HSP 1 Score: 63.929 bits (154), Expect = 2.864e-11
Identity = 35/93 (37.63%), Postives = 54/93 (58.06%), Query Frame = 3

Query:  465 ITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            + EL++E   R Q    EK+K+E LLYQ++P   A QL++   V+ + F+S SI F++I  F   +A   P E+V  LN ++  FD  I+  D
Sbjct:  832 LEELVEE---RTQAYHEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVSIYFSDIVGFTALSAESTPMEVVTLLNDLYTCFDAVIDNFD 921

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Planmine SMEST
Match: SMESG000060260.1 (SMESG000060260.1)

HSP 1 Score: 377.867 bits (969), Expect = 5.607e-128
Identity = 216/218 (99.08%), Postives = 216/218 (99.08%), Query Frame = 3

Query:    3 TDYYTIQLYTLMNNCRSDGISAGSWIAAGKLNSVNNSLNRLKYQINPNNITKYLTSEYMKTTFSPLINENFSIYCLQNQSAFVFLFIEYYEEFQSFHRXXXXXXXXXXRDLLSSDRTSQINWSISMAXXXXXXXXXXXXXXXXXQRKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDF 656
            TDYYTIQLYTLMNNCRSDGISAGSWIAAGKLNSVNNSLNRLKYQINPNNITKYLTSEYMKTTFSPLINENFSIYCLQNQSAFVFLFIEYYEEFQSFHRSVVVQAVSSVRDLLSSDRTSQINWSISMALIFGFLLSFFSLCTFWFQRKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISN  F
Sbjct:  176 TDYYTIQLYTLMNNCRSDGISAGSWIAAGKLNSVNNSLNRLKYQINPNNITKYLTSEYMKTTFSPLINENFSIYCLQNQSAFVFLFIEYYEEFQSFHRSVVVQAVSSVRDLLSSDRTSQINWSISMALIFGFLLSFFSLCTFWFQRKLHRKLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNLIF 393

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Planmine SMEST
Match: SMESG000041839.1 (SMESG000041839.1)

HSP 1 Score: 65.4698 bits (158), Expect = 5.451e-12
Identity = 32/84 (38.10%), Postives = 49/84 (58.33%), Query Frame = 3

Query:  483 ETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIE 734
            E + R +    EKK++E LLYQM+P+  A QLRQ + V+ + F+S SI F++I  F        P E++  LN ++  FD  I+
Sbjct:  924 EVMKRTEELREEKKQNEELLYQMLPIPVAEQLRQHKQVEAEAFDSVSIYFSDIVGFTELAGFCSPFEVINLLNQLYTSFDKIID 1007

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Planmine SMEST
Match: SMESG000056474.1 (SMESG000056474.1)

HSP 1 Score: 64.6994 bits (156), Expect = 1.207e-11
Identity = 30/92 (32.61%), Postives = 55/92 (59.78%), Query Frame = 3

Query:  468 TELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
             +L ++  +R    ETE+KK+E L+ +M+P   A  L   +PV+P+ F+  +I F++I  F   +A+  P ++V  LN ++ +FD  I+ +D
Sbjct:  777 ADLEEQVRVRTDELETEQKKTELLIARMLPRMVAQSLLAGKPVEPESFDEVTIYFSDIVGFTTISALSNPMQVVDLLNDLYTMFDATIDFYD 868

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Planmine SMEST
Match: SMESG000005445.1 (SMESG000005445.1)

HSP 1 Score: 62.003 bits (149), Expect = 8.879e-11
Identity = 30/83 (36.14%), Postives = 46/83 (55.42%), Query Frame = 3

Query:  495 RKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R Q    EK+++E LLY M+P   A QL +  PV  + FE  +I F++I  F   +A   P +++  LN ++ +FD   E HD
Sbjct:  914 RTQQYYEEKRRAEDLLYSMLPKSVAGQLIRGEPVTAESFEKVTIYFSDICGFTALSAESTPMQVITLLNNLYTLFDSITEDHD 996

[Close]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Planmine SMEST
Match: SMESG000010241.1 (SMESG000010241.1)

HSP 1 Score: 59.3066 bits (142), Expect = 6.632e-10
Identity = 30/83 (36.14%), Postives = 48/83 (57.83%), Query Frame = 3

Query:  495 RKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKPKLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD 743
            R +    EKKK+E LLY M+P   A+QL + +PV  + ++  +I F++I  F   +A   P +I+  LN ++  FD  IE +D
Sbjct:  912 RTEQYLEEKKKAEDLLYSMLPKSVAHQLIKNQPVNAESYDLVTIFFSDIVGFTALSAESTPMQIIDLLNRLYTTFDSIIENYD 994

The following BLAST results are available for this feature:

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Human
BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Celegans
BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Fly
BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Zebrafish
BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Xenopus
BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Mouse
BLAST of guanylate cyclase soluble subunit beta-2-like vs. UniProt/SwissProt
BLAST of guanylate cyclase soluble subunit beta-2-like vs. TrEMBL
BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Cavefish
BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Sea Lamprey
BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Yeast
BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Nematostella
BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Medaka
BLAST of guanylate cyclase soluble subunit beta-2-like vs. Planmine SMEST

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NPR1	8.749e-11	35.48	natriuretic peptide receptor 1 [Source:HGNC Symbol...	[more]
GUCY1B1	1.586e-10	37.76	guanylate cyclase 1 soluble subunit beta 1 [Source...	[more]
GUCY1B1	1.674e-10	37.76	guanylate cyclase 1 soluble subunit beta 1 [Source...	[more]
GUCY1B1	1.686e-10	37.76	guanylate cyclase 1 soluble subunit beta 1 [Source...	[more]
GUCY1B1	1.793e-10	37.76	guanylate cyclase 1 soluble subunit beta 1 [Source...	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gcy-6	2.444e-12	34.44	Receptor-type guanylate cyclase gcy-6 [Source:Uni...	[more]
gcy-6	2.465e-12	34.44	Receptor-type guanylate cyclase gcy-6 [Source:Uni...	[more]
gcy-7	5.271e-12	34.78	Receptor-type guanylate cyclase gcy-7 [Source:Uni...	[more]
gcy-7	5.942e-12	34.78	Receptor-type guanylate cyclase gcy-7 [Source:Uni...	[more]
gcy-22	8.329e-12	33.70	Receptor-type guanylate cyclase gcy-22 [Source:Un...	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG33958	6.544e-14	43.42	gene:FBgn0053958 transcript:FBtr0099994	[more]
Gycbeta100B	1.241e-11	34.00	gene:FBgn0013973 transcript:FBtr0085753	[more]
CG31183	3.500e-11	37.63	gene:FBgn0051183 transcript:FBtr0346151	[more]
CG31183	3.500e-11	37.63	gene:FBgn0051183 transcript:FBtr0083187	[more]
CG10738	8.304e-11	35.56	gene:FBgn0036368 transcript:FBtr0304792	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gucy1b2	3.160e-12	37.50	guanylate cyclase 1, soluble, beta 2 [Source:ZFIN;...	[more]
gucy2d	4.556e-12	34.31	guanylate cyclase 2D, retinal [Source:ZFIN;Acc:ZDB...	[more]
gucy2d	4.581e-12	34.31	guanylate cyclase 2D, retinal [Source:ZFIN;Acc:ZDB...	[more]
gucy2d	4.641e-12	34.31	guanylate cyclase 2D, retinal [Source:ZFIN;Acc:ZDB...	[more]
gucy2d	4.807e-12	34.31	guanylate cyclase 2D, retinal [Source:ZFIN;Acc:ZDB...	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ank1	4.223e-12	39.77	ankyrin 1 [Source:Xenbase;Acc:XB-GENE-5838516]	[more]
slc8a3	4.899e-12	34.31	solute carrier family 8 (sodium/calcium exchanger)...	[more]
slc8a3	4.899e-12	34.31	solute carrier family 8 (sodium/calcium exchanger)...	[more]
slc8a3	5.340e-12	34.31	solute carrier family 8 (sodium/calcium exchanger)...	[more]
slc8a3	5.508e-12	34.31	solute carrier family 8 (sodium/calcium exchanger)...	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Gucy1b2	1.132e-14	39.77	guanylate cyclase 1, soluble, beta 2 [Source:MGI S...	[more]
Gucy1b2	1.373e-14	39.77	guanylate cyclase 1, soluble, beta 2 [Source:MGI S...	[more]
Gucy2e	1.291e-11	34.31	guanylate cyclase 2e [Source:MGI Symbol;Acc:MGI:10...	[more]
Gucy2e	1.291e-11	34.31	guanylate cyclase 2e [Source:MGI Symbol;Acc:MGI:10...	[more]
Gucy2e	1.291e-11	34.31	guanylate cyclase 2e [Source:MGI Symbol;Acc:MGI:10...	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P22717\|GCYB2_RAT	1.028e-13	40.91	Guanylate cyclase soluble subunit beta-2 OS=Rattus...	[more]
sp\|O75343\|GCYB2_HUMAN	2.372e-12	39.08	Guanylate cyclase soluble subunit beta-2 OS=Homo s...	[more]
sp\|N1NVB7\|GCY6_CAEEL	3.109e-11	34.44	Receptor-type guanylate cyclase gcy-6 OS=Caenorhab...	[more]
sp\|H2L002\|GCY7_CAEEL	6.705e-11	34.78	Receptor-type guanylate cyclase gcy-7 OS=Caenorhab...	[more]
sp\|P52785\|GUC2E_MOUSE	9.030e-11	34.31	Retinal guanylyl cyclase 1 OS=Mus musculus OX=1009...	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
G3PRL3	1.783e-13	45.45	Guanylate cyclase 1, soluble, beta 2 OS=Gasteroste...	[more]
R7UFR9	2.346e-12	43.42	Guanylate cyclase domain-containing protein OS=Cap...	[more]
A0A0F8ARX1	3.158e-12	43.18	Guanylate cyclase soluble subunit beta-2 OS=Larimi...	[more]
A0A3Q1IDN3	3.394e-12	42.05	Guanylate cyclase 1, soluble, beta 2 OS=Anabas tes...	[more]
A0A0F8AVG5	3.957e-12	43.18	Guanylate cyclase soluble subunit beta-2 OS=Larimi...	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gucy1b2	2.137e-13	39.77	guanylate cyclase 1, soluble, beta 2 [Source:ZFIN;...	[more]
gucy1b2	2.234e-13	39.77	guanylate cyclase 1, soluble, beta 2 [Source:ZFIN;...	[more]
ENSAMXT00000016107.2	1.047e-12	36.14	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
gc2	7.757e-12	36.27	retinal guanylyl cyclase 2 [Source:NCBI gene;Acc:1...	[more]
ENSAMXT00000020840.2	1.241e-11	37.25	retinal guanylyl cyclase 2 [Source:NCBI gene;Acc:1...	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gucy1b2	6.873e-13	39.74	guanylate cyclase 1, soluble, beta 2 [Source:ZFIN;...	[more]
ENSPMAT00000006352.1	2.800e-11	36.56	pep scaffold:Pmarinus_7.0:GL477176:19246:83539:-1 ...	[more]
ENSPMAT00000002650.1	9.417e-11	33.71	pep scaffold:Pmarinus_7.0:GL478983:4063:28109:1 ge...	[more]
NPR1	2.594e-10	35.56	natriuretic peptide receptor 1 [Source:HGNC Symbol...	[more]
ENSPMAT00000000043.1	7.392e-8	28.43	pep scaffold:Pmarinus_7.0:GL480785:4349:14716:1 ge...	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO44983	2.795e-11	33.73	Guanylate cyclase [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36204	8.424e-11	33.73	Guanylate cyclase [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27923	2.034e-10	33.73	Guanylate cyclase [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36203	9.031e-10	34.83	Guanylate cyclase [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47084	1.550e-9	32.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
olgc3	2.478e-12	32.35	membrane guanylyl cyclase [Source:NCBI gene;Acc:10...	[more]
olgc3	2.490e-12	32.35	membrane guanylyl cyclase [Source:NCBI gene;Acc:10...	[more]
olgc-r2	5.885e-12	38.24	guanylate cyclase OlGC-R2 [Source:NCBI gene;Acc:10...	[more]
olgc5	6.919e-12	32.35	guanylate cyclase OlGC5 [Source:NCBI gene;Acc:1001...	[more]
olgc2	2.864e-11	37.63	membrane guanylyl cyclase [Source:NCBI gene;Acc:10...	[more]

BLAST of guanylate cyclase soluble subunit beta-2-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000060260.1	5.607e-128	99.08	SMESG000060260.1	[more]
SMESG000041839.1	5.451e-12	38.10	SMESG000041839.1	[more]
SMESG000056474.1	1.207e-11	32.61	SMESG000056474.1	[more]
SMESG000005445.1	8.879e-11	36.14	SMESG000005445.1	[more]
SMESG000010241.1	6.632e-10	36.14	SMESG000010241.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30008141 ID=SMED30008141|Name=guanylate cyclase soluble subunit beta-2-like|organism=Schmidtea mediterranea sexual|type=transcript|length=743bp
TTACTGACTATTATACCATTCAGCTGTATACATTAATGAATAATTGTCGT
TCCGACGGGATAAGTGCCGGAAGTTGGATAGCCGCAGGGAAACTGAACTC
GGTGAATAATTCTCTGAATAGACTGAAATATCAAATAAATCCCAACAATA
TTACAAAATATCTCACATCCGAGTATATGAAAACAACATTTTCCCCTTTA
ATAAACGAAAACTTTTCGATATATTGTTTGCAGAACCAATCGGCATTTGT
GTTCTTGTTTATCGAGTATTATGAGGAATTTCAAAGTTTTCATCGGTCGG
TTGTTGTTCAAGCTGTCTCCAGTGTTCGAGATCTTCTTTCTTCGGACAGA
ACTTCACAGATCAACTGGTCTATATCAATGGCACTGATATTCGGATTTCT
CCTCAGTTTTTTTAGCCTGTGCACGTTTTGGTTTCAGCGAAAACTCCACC
GAAAACTGACCGTTATCACTGAGCTCATCGACGAGACAATTATCAGGAAA
CAACATCAGGAAACTGAGAAAAAGAAAAGCGAGACTTTATTATATCAAAT
GATTCCGGTTGAAGCGGCCAATCAGTTGCGACAAAAAAGACCTGTTAAAC
CGAAATTGTTCGAAAGTTGTTCAATATTGTTTACTGAAATTTCGAATTTT
GATTTTTTCACTGCCGTTCTTCCGCCAACTGAGATCGTGAGGTTCCTTAA
CCTTGTTTTCAATGTATTTGATGATGAAATAGAGTTACACGAC

protein sequence of SMED30008141-orf-1

>SMED30008141-orf-1 ID=SMED30008141-orf-1|Name=SMED30008141-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=247bp
TDYYTIQLYTLMNNCRSDGISAGSWIAAGKLNSVNNSLNRLKYQINPNNI
TKYLTSEYMKTTFSPLINENFSIYCLQNQSAFVFLFIEYYEEFQSFHRSV
VVQAVSSVRDLLSSDRTSQINWSISMALIFGFLLSFFSLCTFWFQRKLHR
KLTVITELIDETIIRKQHQETEKKKSETLLYQMIPVEAANQLRQKRPVKP
KLFESCSILFTEISNFDFFTAVLPPTEIVRFLNLVFNVFDDEIELHD

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000074	oocyte
PLANA:0000231	vitelline gland

Vocabulary: **INTERPRO**
Term	Definition
IPR001054	A/G_cyclase
IPR029787	Nucleotide_cyclase

Vocabulary: **biological process**
Term	Definition
GO:0009190	cyclic nucleotide biosynthetic process
GO:0035556	intracellular signal transduction
GO:0006182	cGMP biosynthetic process
GO:0007165	signal transduction

Vocabulary: **molecular function**
Term	Definition
GO:0016849	phosphorus-oxygen lyase activity
GO:0000166	nucleotide binding
GO:0004383	guanylate cyclase activity
GO:0005525	GTP binding
GO:0016829	lyase activity
GO:0020037	heme binding
GO:0043167	ion binding
GO:0046872	metal ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0008074	guanylate cyclase complex, soluble

Main menu

guanylate cyclase soluble subunit beta-2-like

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

Owlery

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