TPR repeat-containing protein DDB_G0287407 isoform X2
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008115 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Zebrafish
Match: ttc41 (tetratricopeptide repeat domain 41 [Source:ZFIN;Acc:ZDB-GENE-110914-190]) HSP 1 Score: 86.6557 bits (213), Expect = 2.417e-16 Identity = 110/438 (25.11%), Postives = 190/438 (43.38%), Query Frame = 2 Query: 320 VSINLDSIKQNGSISICLLGENFER-LPKLYEDIGYDYPEFLENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFR--------VSGGPISDDDDGNEN-----EIESKQPSSENDRMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFERFPDKISXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDF--YRKDFSDKLSVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQS-KTKNTDVICIPYYCEASYASSDLQKMLNSLIKRIRLDCGYNLEQDDYETYSLETEMLSLSQKFLGAMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFK-RTDIAIIEVLP 1579 + I+LD + ++ S ICLLG ++ + LP DI + L IAA SGYPW+ + S+ E+ + + FYF+ +DDDG+E ++ SKQ E R+ +LK+ +I LP++F+ + E + RKD +E KIS KD + + ++ + S S +L W + P E LN F + + N L + + + +LV++G RG GKS++ LQ+ +N D+ I ++C S +S+D++ +L ++R +N + D++ T + + A A N+ +L+I S +++KS W+P V+P ++IIT+T +D L F RTD+ I++ P Sbjct: 27 LKISLDLVDRS-SFFICLLGHSYGQCLP----DIESCSSSEVVRKLNIAASSGYPWVLE-DEYRTCSLTELEITKAAFIDNHRLCFFYFKDYTPQDTEDDDDDDDNDDDGSEEMSIFLDMLSKQSQRERQRLRDLKRRIINHCLPVRFFRNQYELGEMIRKD----WEEVISKIS-------------KDSKHLISGWQDSFDLHSH-KSYSRALCNWFV------PSVPATETLNAFDKFLHPVTHNAKYETHAKNPGALFNSDLNDSEKSVLVISGERGCGKSTLAAWCLQTFSEQNPDLPVIRHFCGTSTSSTDVRSLLRLCTAQLRK--AHNGDSPDWDESLENTSEFEYLHRAVQAFTAALNLRPCILLIDGIDLLTET-LGLSKQEVKSLQWLPAVLPPFCKMIITTTFTD--LTHKSFSCRTDVQILKCPP 429
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Xenopus
Match: ccnol.13 (Putative ortholog of g2/mitotic-specific cyclin B3, 13 of 14 [Source:Xenbase;Acc:XB-GENE-940407]) HSP 1 Score: 100.138 bits (248), Expect = 2.980e-20 Identity = 118/502 (23.51%), Postives = 213/502 (42.43%), Query Frame = 2 Query: 140 PFIISSGDDFTYELNAIKNEIFPSVKSYYFPKKHFSVNCFDLIYP-NPKPMDILSNPLKDFVSINLDSIKQNGSISICLLGENF-ERLPKLYEDIGY------DYPEF--LENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPISDDDDGNENEIESKQPS--SEND----RMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFER-FPDKISXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDFYRKDFSDKL---SVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQS-KTKNTDVICIPYYCEASYASSDLQKMLNSLIKRIRLDCGY-NLEQDDYETYSLETEMLS---LSQKFLGAMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIE 1570 P++ S+ DF E N + IF + + + + S DL +P +P + + + ++++LD I+++ IC+LG + E +P+ + D+ +E L +AA+SGY W+ N + S+ E+ + ++ + FYFR NE E ++ + SEND ++ LK ++ +G P++F+ + E KD DI ER +P K+ + K F+E L K + SN ++ +L+DF ++K S+ ++ L + + ILVL G RG GKS+I W S +T N D+ I Y+ +S SS++ + I L C Y ++ +D T+M + L + FL + L + I + +Q K W+P +P+ +II+T++ + S +K R+D+ + E Sbjct: 17 PYVCSTIKDFQEERNYLSKNIFEQLNDFCYARG-TSFKAVDLRWPLEGQPYHVKPFNVAEQLTLSLDYIERSSPFFICILGHTYGEFIPEAHSHCPINSVSISDFSALPNVEQKLVVAANSGYSWLLEGGNRE-CSITELEIHHAAFSRDVGFQYFYFRDHVCIEEQLHKANEEEKKTILSTFESENDYERTKIWELKIRIVDKGFPVRFFKTKEELGNLVLKDWCDIIERLYP------------LSATPKNIGHEHSLQHAYNKAFAE------CLCKDFVPTEQSN---KLLTVLDDFVFGAQAEKQSTHSLGSESIDCDVLHNTAARSGAASILVLYGDRGCGKSTIAAKWFNSFRTNNPDITVISYFVGSSGRSSNIMSFMRYCI--TVLQCEYFGVQAEDLMNNENSTDMWAFPLLLEVFLSCITLKPCVLLLDGIDGLSGIN-----GIPAEQAKGFLWLPVNLPDYCKIILTTSPTHLSFKCLKV-RSDVVLAE 487
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Mouse
Match: Ttc41 (tetratricopeptide repeat domain 41 [Source:MGI Symbol;Acc:MGI:2387653]) HSP 1 Score: 70.4774 bits (171), Expect = 1.605e-11 Identity = 119/515 (23.11%), Postives = 209/515 (40.58%), Query Frame = 2 Query: 137 FPFIISSGDDFTYELNAIKNEIFPSVKSYYFPKKHFSVNCFDLIYPNPKPM-DILSNPLKDF-------VSINLDSIKQNGSISICLLGENFERLPKLYEDIGYDYPEFL-------------ENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPI---SDDDDGNENEIESKQPSSENDRME--NLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFERFPDKISXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDFYRKDFSDKLSV--TIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQS-KTKNTDVICIPYYCEASYASSDLQKMLNSLIKRI-------RLDCGYNLEQDDYETYSLETEMLSLSQKFLGAMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEV 1573 P+I S+ DF E + + IFP + + + DL + K SN + + + ++LD + + I LLG+ Y D DY FL E +L IAA +GYPW+ N S+ E + ++ FYFR S + +++++ E ++ S +E +M+ LK +I +GLP++FY E KD + E+ M + + L F EN K++F T E+N R E+L F KD L TI ++ I++ IL+L+G RG GKS+++ NW+ + ++K+ V+ IPY+ ++ S D+ +++ + + RL+ + E + +SL E+ + +L+ I + I S ++ K W+P +P + + I S+ S S + R D+ I+E+ Sbjct: 25 LPYICST-LDFQEERDFLAKSIFPRLNDICSSRGTY-FKAVDLRWSAVKAHKSFTSNQFRQYSCLQSQHLKLSLDYVNRCFPFFIGLLGQT-------YGDFLPDYTPFLLSQVKDFESLSKGEQNLYIAAKNGYPWVLKTPN---CSLTEFEIIQAVFRKKSQFQFFYFRTSNSLLRTFNEEEEEEEEKLSSAYLLNEQGKMKVGKLKAKIIGKGLPVRFYRDLEELGDMVWKDWSAVVEKL---YPFTTIMGNIDYKHSFENLYHEEFVENCKQVFV------------TSKESN-----RTFEILERFAIKDLDLDLDTDSTIAGSGLDSILRINSLPTCKSILLLSGERGCGKSTLIANWVSNFQSKHPGVLMIPYFVGSTCESCDIMSVIHYFVMELQHRANGPRLEMDFLNEDSNVLVFSLLVEVFIAAISLKPCILVLDGIEELIGIY-----------GISGQKAKDFSWLPRSLPPHCK-FILSSVSSSLSCKSLCARPDVKIVEL 495
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Mouse
Match: Ttc41 (tetratricopeptide repeat domain 41 [Source:MGI Symbol;Acc:MGI:2387653]) HSP 1 Score: 70.4774 bits (171), Expect = 2.579e-11 Identity = 122/521 (23.42%), Postives = 212/521 (40.69%), Query Frame = 2 Query: 137 FPFIISSGDDFTYELNAIKNEIFP------SVKSYYFPKKHFSVNCFDLIYPNPKPM-DILSNPLKDF-------VSINLDSIKQNGSISICLLGENFERLPKLYEDIGYDYPEFL-------------ENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPI---SDDDDGNENEIESKQPSSENDRME--NLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFERFPDKISXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDFYRKDFSDKLSV--TIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQS-KTKNTDVICIPYYCEASYASSDLQKMLNSLIKRI-------RLDCGYNLEQDDYETYSLETEMLSLSQKFLGAMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEV 1573 P+I S+ DF E + + IFP S + YF DL + K SN + + + ++LD + + I LLG+ Y D DY FL E +L IAA +GYPW+ N S+ E + ++ FYFR S + +++++ E ++ S +E +M+ LK +I +GLP++FY E KD + E+ M + + L F EN K++F T E+N R E+L F KD L TI ++ I++ IL+L+G RG GKS+++ NW+ + ++K+ V+ IPY+ ++ S D+ +++ + + RL+ + E + +SL E+ + +L+ I + I S ++ K W+P +P + + I++S +S S + R D+ I+E+ Sbjct: 25 LPYICST-LDFQEERDFLAKSIFPRLNDICSSRGTYF-------KAVDLRWSAVKAHKSFTSNQFRQYSCLQSQHLKLSLDYVNRCFPFFIGLLGQT-------YGDFLPDYTPFLLSQVKDFESLSKGEQNLYIAAKNGYPWVLKTPN---CSLTEFEIIQAVFRKKSQFQFFYFRTSNSLLRTFNEEEEEEEEKLSSAYLLNEQGKMKVGKLKAKIIGKGLPVRFYRDLEELGDMVWKDWSAVVEKL---YPFTTIMGNIDYKHSFENLYHEEFVENCKQVFV------------TSKESN-----RTFEILERFAIKDLDLDLDTDSTIAGSGLDSILRINSLPTCKSILLLSGERGCGKSTLIANWVSNFQSKHPGVLMIPYFVGSTCESCDIMSVIHYFVMELQHRANGPRLEMDFLNEDSNVLVFSLLVEVFIAAISLKPCILVLDGIEELIGIY-----------GISGQKAKDFSWLPRSLPPHCKFILSSVSSSLS-CKSLCARPDVKIVEL 495
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Mouse
Match: Ttc41 (tetratricopeptide repeat domain 41 [Source:MGI Symbol;Acc:MGI:2387653]) HSP 1 Score: 67.0106 bits (162), Expect = 1.081e-10 Identity = 98/403 (24.32%), Postives = 170/403 (42.18%), Query Frame = 2 Query: 140 PFIISSGDDFTYELNAIKNEIFPSVKSYYFPKKHFSVNCFDLIYPNPKPM-DILSNPLKDF-------VSINLDSIKQNGSISICLLGENFERLPKLYEDIGYDYPEFL-------------ENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPI---SDDDDGNENEIESKQPSSENDRME--NLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFER-FPDKISXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDFYRKDFSDKLSV--TIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQS-KTKNTDVICIPYYCEASYASSDLQKMLNSLIKRIR 1258 P+I S+ DF E + + IFP + + + DL + K SN + + + ++LD + + I LLG+ Y D DY FL E +L IAA +GYPW+ N S+ E + ++ FYFR S + +++++ E ++ S +E +M+ LK +I +GLP++FY E KD + E+ +P M + + L F EN K++F T E+N R E+L F KD L TI ++ I++ IL+L+G RG GKS+++ NW+ + ++K+ V+ IPY+ ++ S D+ +++ + ++ Sbjct: 26 PYICST-LDFQEERDFLAKSIFPRLNDICSSRGTY-FKAVDLRWSAVKAHKSFTSNQFRQYSCLQSQHLKLSLDYVNRCFPFFIGLLGQT-------YGDFLPDYTPFLLSQVKDFESLSKGEQNLYIAAKNGYPWVLKTPN---CSLTEFEIIQAVFRKKSQFQFFYFRTSNSLLRTFNEEEEEEEEKLSSAYLLNEQGKMKVGKLKAKIIGKGLPVRFYRDLEELGDMVWKDWSAVVEKLYP----FTTIMGNIDYKHSFENLYHEEFVENCKQVFV------------TSKESN-----RTFEILERFAIKDLDLDLDTDSTIAGSGLDSILRINSLPTCKSILLLSGERGCGKSTLIANWVSNFQSKHPGVLMIPYFVGSTCESCDIMSVIHYFVMELQ 395
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Mouse
Match: Ttc41 (tetratricopeptide repeat domain 41 [Source:MGI Symbol;Acc:MGI:2387653]) HSP 1 Score: 67.0106 bits (162), Expect = 1.081e-10 Identity = 98/403 (24.32%), Postives = 170/403 (42.18%), Query Frame = 2 Query: 140 PFIISSGDDFTYELNAIKNEIFPSVKSYYFPKKHFSVNCFDLIYPNPKPM-DILSNPLKDF-------VSINLDSIKQNGSISICLLGENFERLPKLYEDIGYDYPEFL-------------ENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPI---SDDDDGNENEIESKQPSSENDRME--NLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFER-FPDKISXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDFYRKDFSDKLSV--TIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQS-KTKNTDVICIPYYCEASYASSDLQKMLNSLIKRIR 1258 P+I S+ DF E + + IFP + + + DL + K SN + + + ++LD + + I LLG+ Y D DY FL E +L IAA +GYPW+ N S+ E + ++ FYFR S + +++++ E ++ S +E +M+ LK +I +GLP++FY E KD + E+ +P M + + L F EN K++F T E+N R E+L F KD L TI ++ I++ IL+L+G RG GKS+++ NW+ + ++K+ V+ IPY+ ++ S D+ +++ + ++ Sbjct: 26 PYICST-LDFQEERDFLAKSIFPRLNDICSSRGTY-FKAVDLRWSAVKAHKSFTSNQFRQYSCLQSQHLKLSLDYVNRCFPFFIGLLGQT-------YGDFLPDYTPFLLSQVKDFESLSKGEQNLYIAAKNGYPWVLKTPN---CSLTEFEIIQAVFRKKSQFQFFYFRTSNSLLRTFNEEEEEEEEKLSSAYLLNEQGKMKVGKLKAKIIGKGLPVRFYRDLEELGDMVWKDWSAVVEKLYP----FTTIMGNIDYKHSFENLYHEEFVENCKQVFV------------TSKESN-----RTFEILERFAIKDLDLDLDTDSTIAGSGLDSILRINSLPTCKSILLLSGERGCGKSTLIANWVSNFQSKHPGVLMIPYFVGSTCESCDIMSVIHYFVMELQ 395
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. UniProt/SwissProt
Match: sp|Q6P3V7|TTC41_RAT (Tetratricopeptide repeat protein 41 OS=Rattus norvegicus OX=10116 GN=Ttc41 PE=2 SV=2) HSP 1 Score: 77.7962 bits (190), Expect = 1.030e-12 Identity = 97/411 (23.60%), Postives = 158/411 (38.44%), Query Frame = 2 Query: 140 PFIISSGDDFTYELNAIKNEIFPSVKSYYFPKKHFSVNCFDLIYPNPKPMDILSNPL--------KDFVSINLDSIKQNGSISICLLGENFERLPKLYEDIGYDYPEFL-------------ENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPISDDDDGNENEIESKQPSSENDR-----MENLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFERFPDKISXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDFYRKDFSDKLSVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQS-KTKNTDVICIPYYCEASYASSDLQKMLNSLIKRIRLDC-GYNLEQD 1288 P+I S+ DF E + + IFP + + + + DL + K +N + + LD + + ICLLG+ Y D DY FL E +L +AA +GYPW+ N S+ E + ++ FYFR S + + E E E + DR + LK +I +GLP++FY E KD + E M + + L F EN K++F S R E+L F KD T+ ++ I++ IL+L G RG GKS+++ NW+ K+++ V+ +PY+ ++ S D+ +++ I ++ G LE D Sbjct: 26 PYICST-IDFQDERDFLAKTIFPQLNDFCSSRGTY-FKAVDLRWSALKAHKSFTNNQFRQYSCLHSQHLKLCLDYVNRCFPFFICLLGQT-------YGDFLPDYTPFLLSKVKDLESLSKGEQNLYVAAKNGYPWVLKTPN---CSLTEFEIIQAAFRKKSQFQFFYFRTSNSLLRTFSEEEEEEEEKLSSGYQVDRQGKVKVGKLKAKIIGKGLPVRFYRDLDELGDMVLKDWSAVVEEL---YPVTMIMENIDYKHSFENLYHEEFVENCKQVF-----------------VISKESNRTFEMLERFAIKDLELNSDSTVAGAGLDSILRINSLPTCKSILLLCGERGCGKSTLIANWVDDFKSRHPGVLMVPYFVGSTCESCDIMSVMHYFIMELQHRANGPQLEMD 404
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. UniProt/SwissProt
Match: sp|Q6P2S7|TTC41_HUMAN (Putative tetratricopeptide repeat protein 41 OS=Homo sapiens OX=9606 GN=TTC41P PE=5 SV=3) HSP 1 Score: 77.0258 bits (188), Expect = 1.757e-12 Identity = 103/423 (24.35%), Postives = 169/423 (39.95%), Query Frame = 2 Query: 140 PFIISSGDDFTYELNAIKNEIFPSVK------SYYFPKKHFSVNCFDLIYPNPKPMDIL---SNPLKDFVSINLDSIKQNGSISICLLGENFERLPKLYEDIGYDYPEFLEN------------SLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPISDDDDGNENEIESKQPSS------ENDRMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFERFPDKISXXXXXXXXXXXXAKDRLQMFTFNENIKK---IFSEFNSLYTSLTKWTLNET-----NSNPEARIDELLNDFYRKDFSDKLSVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQS-KTKNTDVICIPYY----CEASYASSDLQKMLNSLIKRIRLDCGYNLEQD 1288 P+I S+ +DF E + + N IFP + YF K ++ L P P + S + + LD + IC+LG+ Y D DY F+ + +L +AA +GYPW+ N S+ E L+E ++ FYFR + DD + E + PSS E R+ LK +I +GLP++FY E + KD + E+ + + +R F E K+ I E + + L K+ L + N ++ +D + F R+N + +Y+ IL+L+ G GKS+++ NW+ K K+ ++ IP++ CE+SY S + + L R + G LE D Sbjct: 25 PYICSTLNDFQEERDFLANNIFPQLNELCNSWGTYF--KAVDLSWSALKAPKSLPTHLFRQYSCLRSQRLKLCLDYVNSCFPFFICMLGQT-------YGDFLPDYSHFMTSKVTRLSSLSKVENLYVAAKNGYPWVLE---NPSCSLTEFEIIQAAFLNESQFQYFYFRTGTTLLKALDDEKKGE---RLPSSSSTNEEETLRIGKLKAKIISKGLPVRFYSDLHELGELVFKDWSVVIEKLH---PATLMIENIDYKHSFERFYHEEFTEKCKQMCVISKESDRTFEILEKFALKDVELDFNNVAADSSLDSVPRFF--------------RINP------TPTYKS--ILLLSREHGCGKSTLIANWVNYFKKKHPSMLLIPHFVGSTCESSYIMSVIHYFITELQYR---NYGTQLETD 404
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. UniProt/SwissProt
Match: sp|Q692V3|TTC41_MOUSE (Tetratricopeptide repeat protein 41 OS=Mus musculus OX=10090 GN=Ttc41 PE=1 SV=1) HSP 1 Score: 68.5514 bits (166), Expect = 6.556e-10 Identity = 121/521 (23.22%), Postives = 212/521 (40.69%), Query Frame = 2 Query: 137 FPFIISSGDDFTYELNAIKNEIFP------SVKSYYFPKKHFSVNCFDLIYPNPKPM-DILSNPLKDF-------VSINLDSIKQNGSISICLLGENFERLPKLYEDIGYDYPEFL-------------ENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPI---SDDDDGNENEIESKQPSSENDRME--NLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFERFPDKISXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDFYRKDFSDKLSV--TIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQS-KTKNTDVICIPYYCEASYASSDLQKMLNSLIKRI-------RLDCGYNLEQDDYETYSLETEMLSLSQKFLGAMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEV 1573 P+I S+ DF E + + IFP S + YF DL + K SN + + + ++LD + + I LLG+ Y D DY FL + +L IAA +GYPW+ N S+ E + ++ FYFR S + +++++ E ++ S +E +M+ LK +I +GLP++FY E KD + E+ M + + L F EN K++F T E+N R E+L F KD L TI ++ I++ IL+L+G RG GKS+++ NW+ + ++K+ V+ IPY+ ++ S D+ +++ + + RL+ + E + +SL E+ + +L+ I + I S ++ K W+P +P + + I++S +S S + R D+ I+E+ Sbjct: 25 LPYICST-LDFQEERDFLAKSIFPRLNDICSSRGTYF-------KAVDLRWSAVKAHKSFTSNQFRQYSCLQSQHLKLSLDYVNRCFPFFIGLLGQT-------YGDFLPDYTPFLLSQVKDFESLSKGKKNLYIAAKNGYPWVLKTPN---CSLTEFEIIQAVFRKKSQFQFFYFRTSNSLLRTFNEEEEEEEEKLSSAYLLNEQGKMKVGKLKAKIIGKGLPVRFYRDLEELGDMVWKDWSAVVEKL---YPFTTIMGNIDYKHSFENLYHEEFVENCKQVFV------------TSKESN-----RTFEILERFAIKDLDLDLDTDSTIAGSGLDSILRINSLPTCKSILLLSGERGCGKSTLIANWVSNFQSKHPGVLMIPYFVGSTCESCDIMSVIHYFVMELQHRANGPRLEMDFLNEDSNVLVFSLLVEVFIAAISLKPCILVLDGIEELIGIY-----------GISGQKAKDFSWLPRSLPPHCKFILSSVSSSLS-CKSLCARPDVKIVEL 495
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. TrEMBL
Match: A0A1I8JC28 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 104.375 bits (259), Expect = 1.876e-35 Identity = 136/554 (24.55%), Postives = 238/554 (42.96%), Query Frame = 2 Query: 434 EFLENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPISDDDDGNENEIES--KQPSSEND----RMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMD-IFERFPDKI-----SXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARI-DELLNDFYRKDFSDKLSVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQSKTKNTDV----------------------ICIPYYCEASYASSDLQKMLNSLIKRIRLDCGYNLEQDDYETYSLETEMLSLSQKFLG---AMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEVLPGSIDEQNELIKSGIDGLKTWISKHGQVYPSNFPQPIYSWPLIAN-PLIQKILARVYHTLGTTV-KWKSFIEKASECQTLVELVRRVLKFHIYHINW---ELTVKSDKLKKNYIVNKEEEMEERSIQGWVPDCLS 1966 E+L+ SL+ AA++GY W+ N + SS+ ++ + L K+ Y R + S E E E KQ E+D ++E LKQ LIR+GLPIKF+ + E + D + + R+ D + S D M DQ+I + RLQ N + + ++ + E + A + + L+ F R+D S+ ++ T + + S S +I +L G RG GKS++L +WL++ + V + IPYY A+ AS D + + +R+ N +E L + Q+ +G A L I + + D +G +C ++K W+P +P RI+ ++ +SD + A + +R+D+ I +G + + + + GQ +F + PL + PL Q +LA YH +G T K +F+ + ++ +L +L+ W L KSD+ +K+ + KEE + + WV + L+ Sbjct: 863 EWLKASLKKAAENGYTWLLN-DAYTNSSVNDLQTTLAVFLKACKHCFIYVRSAAHQDSLYRHLGEAERERLLKQFKVESDYAAMKVEELKQRLIRKGLPIKFFTTPDELEQVILADFEEHLGVRYIDSVDLPGMSLFDAMERDQRIEQELRLQGLQINSDFSRCIADIDRFVAD------GEEDDRANASVAHDPLDAFVRRDHSEIMAKT----HLQQHSGARQSATSPRIFLLAGERGCGKSTLLSHWLRNYAETQAVARADAASDGGPAGEAAWLRQQPLVIPYYVGANRASCDAMNFMELVKQRVH----RNFNVRSHEPPFLMLDPAFTYQEVVGSFEAALSMGKILLVIDGLDCFGDSVGCRC----DEVKRLAWLPARLPPGCRIVASTLSSDLTCASLS-RRSDVQIYRF--------GATADTGAEMMANFSADFGQTPGDDFWEAFVESPLAPSCPLAQALLALEYHIVGCTADKRAAFVNAVGDLVSIRQLFLHLLRRWSSEYGWVKLTLMEKSDQTQKS-LFEKEESQIKHEWEDWVSESLA 1387 HSP 2 Score: 78.1814 bits (191), Expect = 1.876e-35 Identity = 49/145 (33.79%), Postives = 72/145 (49.66%), Query Frame = 1 Query: 1966 LLVLSRNGLPLDIILSCLDKLGYVKDFEVVESDVWSLFHLTREIILKFHNEKFKLTHSICKEIVEHAFLAIASCSSVEARTRECQEYMYIDKRCKFHLLLAYHFWNQRNANLENISECVYHLDRGSDYESMETVLFLPRTLLGLF 2400 L+ LSR GL L ILS L +LGY +V D W F + L+ + ++K H EIVEH F + + ++VE R + + R KFH LL +HF + + +E +YH DR S +E + +L P L +F Sbjct: 1388 LIALSRRGLCLQGILSLLGRLGYSSQAQVALFD-WHRFFNSAAGTLQLVDGRYKFIHMHFAEIVEHIFFSCVAPAAVETRCKPSRLPTASGLRYKFHSLLGHHFLEEGDH-----AEAIYHFDRASQFEKLMEILSDPYVFLDVF 1526
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. TrEMBL
Match: A0A267FI96 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013431g1 PE=4 SV=1) HSP 1 Score: 104.76 bits (260), Expect = 5.938e-35 Identity = 136/554 (24.55%), Postives = 238/554 (42.96%), Query Frame = 2 Query: 434 EFLENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPISDDDDGNENEIES--KQPSSEND----RMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMD-IFERFPDKI-----SXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARI-DELLNDFYRKDFSDKLSVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQSKTKNTDV----------------------ICIPYYCEASYASSDLQKMLNSLIKRIRLDCGYNLEQDDYETYSLETEMLSLSQKFLG---AMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEVLPGSIDEQNELIKSGIDGLKTWISKHGQVYPSNFPQPIYSWPLIAN-PLIQKILARVYHTLGTTV-KWKSFIEKASECQTLVELVRRVLKFHIYHINW---ELTVKSDKLKKNYIVNKEEEMEERSIQGWVPDCLS 1966 E+L+ SL+ AA++GY W+ N + SS+ ++ + L K+ Y R + S E E E KQ E+D ++E LKQ LIR+GLPIKF+ + E + D + + R+ D + S D M DQ+I + RLQ N + + ++ + E + A + + L+ F R+D S+ ++ T + + S S +I +L G RG GKS++L +WL++ + V + IPYY A+ AS D + + +R+ N +E L + Q+ +G A L I + + D +G +C ++K W+P +P RI+ ++ +SD + A + +R+D+ I +G + + + + GQ +F + PL + PL Q +LA YH +G T K +F+ + ++ +L +L+ W L KSD+ +K+ + KEE + + WV + L+ Sbjct: 158 EWLKASLKKAAENGYTWLLN-DAYTNSSVNDLQTTLAVFLKACKHCFIYVRSAAHQDSLYRHLGEAERERLLKQFKVESDYAAMKVEELKQRLIRKGLPIKFFTTPDELEQVILADFEEHLGVRYIDSVDLPGMSLFDAMERDQRIEQELRLQGLQINSDFSRCIADIDRFVAD------GEEDDRANASVAHDPLDAFVRRDHSEIMAKT----HLQQHSGARQSATSPRIFLLAGERGCGKSTLLSHWLRNYAETQAVARADAASDGGPAGEAAWLRQQPLVIPYYVGANRASCDAMNFMELVKQRVH----RNFNVRSHEPPFLMLDPAFTYQEVVGSFEAALSMGKILLVIDGLDCFGDSVGCRC----DEVKRLAWLPARLPPGCRIVASTLSSDLTCASLS-RRSDVQIYRF--------GATADTGAEMMANFSADFGQTPGDDFWEAFVESPLAPSCPLAQALLALEYHIVGCTADKRAAFVNAVGDLVSIRQLFLHLLRRWSSEYGWVKLTLMEKSDQTQKS-LFEKEESQIKHEWEDWVSESLA 682 HSP 2 Score: 75.8702 bits (185), Expect = 5.938e-35 Identity = 49/146 (33.56%), Postives = 72/146 (49.32%), Query Frame = 1 Query: 1966 LLVLSRNGLPLDIILSCLDKLGYVKDFEVVESDVWSLFHLTREIILKFHNEKFKLTHSICKEIVEHAFLAIASCSSVEARTRECQEYMYIDKRCKFHLLLAYHFWNQRNANLENISECVYHLDRGSDYESMETVLFLPRTLLGLFN 2403 L+ LSR GL L ILS L +LGY +V D W F + L+ + ++K H EIVEH F + + ++VE R + + R KFH LL +HF + + +E +YH DR S +E + +L P L +F Sbjct: 683 LIALSRRGLCLQGILSLLGRLGYSSQAQVALFD-WHRFFNSAAGTLQLVDGRYKFIHMHFAEIVEHIFFSCVAPAAVETRCKPSRLPTASGLRYKFHSLLGHHFLEEGDH-----AEAIYHFDRASQFEKLMEILSDPYVFLDVFG 822
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. TrEMBL
Match: A0A1I8JG25 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 104.375 bits (259), Expect = 7.139e-35 Identity = 135/553 (24.41%), Postives = 238/553 (43.04%), Query Frame = 2 Query: 434 EFLENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPISDDDDGNENEIES--KQPSSEND----RMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMD-IFERFPDKI-----SXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDFYRKDFSDKLSVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQSKTKNTDV----------------------ICIPYYCEASYASSDLQKMLNSLIKRIRLDCGYNLEQDDYETYSLETEMLSLSQKFLG---AMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEVLPGSIDEQNELIKSGIDGLKTWISKHGQVYPSNFPQPIYSWPLIAN-PLIQKILARVYHTLGTTV-KWKSFIEKASECQTLVELVRRVLKFHIYHINW---ELTVKSDKLKKNYIVNKEEEMEERSIQGWVPDCLS 1966 E+L+ SL+ AA++GY W+ N + SS+ ++ + L K+ Y R + S E E E KQ E+D ++E LKQ LIR+GLPIKF+ + E + D + + R+ D + S D M DQ+I + RLQ N + + ++ + E + + + L+ F R+D S+ ++ T + + S S + +I +L G RG GKS++L +WL++ + V + IPYY A+ AS D + + +R+ N +E L + Q+ +G A L I + + D +G +C ++K W+P +P RI+ ++ +SD + A + +R+D+ I +G + + + + GQ +F + PL + PL Q +LA YH +G T K +F+ + ++ +L +L+ W L KSD+ +K+ + KEE + + WV + L+ Sbjct: 161 EWLKASLKKAAENGYTWLLN-DAYTNSSVNDLQTTLAVFLKACKHCFIYVRSAAHQDSLYRHLGEAERERLLKQFKVESDYAAMKVEELKQRLIRKGLPIKFFTTPDELEQVILADFEEHLGVRYIDSVDLPGMSLFDAMERDQRIEQELRLQGLQINSDFSRCIADIDRFVAD-----GEEDDRANMSVAHDPLDAFVRRDHSEIMAKT----HLQQHSGARQSAKSPRIFLLAGERGCGKSTLLSHWLRNYAETQAVARADAASDGGPAGEAAWLRRQPLVIPYYVGANRASCDAMNFMELVKQRVH----RNFNVRSHEPPFLMLDPAFTYQEVVGSFEAALSMGKILLVIDGLDCFGDSVGCRC----DEVKRLAWLPARLPPGCRIVASTLSSDLTCASLS-RRSDVQIYRF--------GATADTGAEMMANFSADFGQTPGDDFWEAFVESPLAPSCPLAQALLALEYHIVGCTADKRAAFVNAVGDLVSIRQLFLHLLRRWSSEYGWVKLTLMEKSDQTQKS-LFEKEESQIKHEWEDWVSESLA 685 HSP 2 Score: 76.2554 bits (186), Expect = 7.139e-35 Identity = 49/146 (33.56%), Postives = 72/146 (49.32%), Query Frame = 1 Query: 1966 LLVLSRNGLPLDIILSCLDKLGYVKDFEVVESDVWSLFHLTREIILKFHNEKFKLTHSICKEIVEHAFLAIASCSSVEARTRECQEYMYIDKRCKFHLLLAYHFWNQRNANLENISECVYHLDRGSDYESMETVLFLPRTLLGLFN 2403 L+ LSR GL L ILS L +LGY +V D W F + L+ + ++K H EIVEH F + + ++VE R + + R KFH LL +HF + + +E +YH DR S +E + +L P L +F Sbjct: 686 LIALSRRGLCLQGILSLLGRLGYSSQAQVALFD-WHRFFNSAAGTLQLVDGRYKFIHMHFAEIVEHIFFSCVAPAAVETRCKPSRLPTASGLRYKFHSLLGHHFLEEGDH-----AEAIYHFDRASQFEKLMEILSDPYVFLDVFG 825
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. TrEMBL
Match: A0A1I8HRS8 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 103.605 bits (257), Expect = 1.062e-34 Identity = 135/553 (24.41%), Postives = 239/553 (43.22%), Query Frame = 2 Query: 434 EFLENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPISDDDDGNENEIES--KQPSSEND----RMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMD-IFERFPDKI-----SXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDFYRKDFSDKLSVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQSKTKNTDV----------------------ICIPYYCEASYASSDLQKMLNSLIKRIRLDCGYNLEQDDYETYSLETEMLSLSQKFLG---AMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEVLPGSIDEQNELIKSGIDGLKTWISKHGQVYPSNFPQPIYSWPLIAN-PLIQKILARVYHTLGTTV-KWKSFIEKASECQTLVELVRRVLKFHIYHINW---ELTVKSDKLKKNYIVNKEEEMEERSIQGWVPDCLS 1966 E+L+ SL+ AA++GY W+ N + SS+ ++ + L K+ Y R + S E E E KQ E+D ++E LKQ LIR+GLPIKF+ + E + D + + R+ D + S D M DQ+I + RLQ N + + ++ + E + + + L+ F R+D S+ ++ T L + + + S + +I +L G RG GKS++L +WL++ + V + IPYY A+ AS D + + +R+ N +E L + Q+ +G A L I + + D +G +C ++K W+P +P RI+ ++ +SD + A + +R+D+ I +G + + + + GQ +F + PL + PL Q +LA YH +G T K +F+ + ++ +L +L+ W L KSD+ +K+ + KEE + + WV + L+ Sbjct: 161 EWLKASLKKAAENGYTWLLN-DAYTNSSVNDLQTTLAVFLKACKHCFVYVRSAAHQDSLYRHLGEAERERLLKQFKVESDYAAMKVEELKQRLIRKGLPIKFFTTPDELEQVILADFEEHLGVRYIDSVDLPGMSLFDAMERDQRIEQELRLQGLQINSDFSRCIADIDRFVAD-----GEEDDRANMSVAHDPLDAFVRRDHSEIMAKT--HLQQHSGARQSAT--SPRIFLLAGERGCGKSTLLSHWLRNYAETQAVARADAASDGGPAGEAAWLRRQPLVIPYYVGANRASCDAMNFMELVKQRVH----RNFNVRSHEPPFLMLDPAFTYQEVVGSFEAALSMGKILLVIDGLDCFGDSVGCRC----DEVKRLAWLPARLPPGCRIVASTLSSDLTCASLS-RRSDVQIYRF--------GATADTGAEMMANFSADFGQTPGDDFWEAFVESPLAPSCPLAQALLALEYHIVGCTADKRAAFVNAVGDLVSIRQLFLHLLRRWSSEYGWVKLTLMEKSDQTQKS-LFEKEESQIKHEWEDWVSESLA 685 HSP 2 Score: 76.2554 bits (186), Expect = 1.062e-34 Identity = 49/146 (33.56%), Postives = 72/146 (49.32%), Query Frame = 1 Query: 1966 LLVLSRNGLPLDIILSCLDKLGYVKDFEVVESDVWSLFHLTREIILKFHNEKFKLTHSICKEIVEHAFLAIASCSSVEARTRECQEYMYIDKRCKFHLLLAYHFWNQRNANLENISECVYHLDRGSDYESMETVLFLPRTLLGLFN 2403 L+ LSR GL L ILS L +LGY +V D W F + L+ + ++K H EIVEH F + + ++VE R + + R KFH LL +HF + + +E +YH DR S +E + +L P L +F Sbjct: 686 LIALSRRGLCLQGILSLLGRLGYSSQAQVALFD-WHRFFNSAAGTLQLVDGRYKFIHMHFAEIVEHIFFSCVAPAAVETRCKPSRLPTASGLRYKFHSLLGHHFLEEGDH-----AEAIYHFDRASQFEKLMEILSDPYVFLDVFG 825
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. TrEMBL
Match: A0A1I8JAW9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 103.605 bits (257), Expect = 1.153e-34 Identity = 136/553 (24.59%), Postives = 240/553 (43.40%), Query Frame = 2 Query: 434 EFLENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPISDDDDGNENEIES--KQPSSEND----RMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMD-IFERFPDKI-----SXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDFYRKDFSDKLSVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQSKTKNTDV----------------------ICIPYYCEASYASSDLQKMLNSLIKRIRLDCGYNLEQDDYETYSLETEMLSLSQKFLG---AMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEVLPGSIDEQNELIKSGIDGLKTWISKHGQVYPSNFPQPIYSWPLIAN-PLIQKILARVYHTLGTTV-KWKSFIEKASECQTLVELVRRVLKFHIYHINW---ELTVKSDKLKKNYIVNKEEEMEERSIQGWVPDCLS 1966 E+L+ SL+ AA++GY W+ N + SS+ ++ + L K+ Y R + S E E E KQ E+D ++E LKQ LIR+GLPIKF+ + E + D + + R+ D + S D M DQ+I + RLQ N + + ++ + + + +N D L+ F R+D S+ ++ T L + + + S + +I +L G RG GKS++L +WL++ + V + IPYY A+ AS D + + +R+ N +E L + Q+ +G A L I + + D +G +C ++K W+P +P RI+ ++ +SD + A + +R+D+ I +G + + + + GQ +F + PL + PL Q +LA YH +G T K +F+ + ++ +L +L+ W L KSD+ +K+ + KEE + + WV + L+ Sbjct: 161 EWLKASLKKAAENGYTWLLN-DAYTNSSVNDLQTTLAVFLKACKHCFIYVRSAAHQDSLYRHLGEAERERLLKQFKVESDYAAMKVEELKQRLIRKGLPIKFFTTPDELEQVILADFEEHLGVRYIDSVDLPGMSLFDAMERDQRIEQELRLQGLQINSDFSRCIADIDRFVADGEE----DDRANMSVAHDP-LDAFVRRDHSEIMAKT--HLQQHSGARQSAT--SPRIFLLAGERGCGKSTLLSHWLRNYAETQAVARADAASDGGPAGEAAWLRRQPLVIPYYVGANRASCDAMNFMELVKQRVH----RNFNVRSHEPPFLMLDPAFTYQEVVGSFEAALSMGKILLVIDGLDCFGDSVGCRC----DEVKRLAWLPARLPPGCRIVASTLSSDLTCASLS-RRSDVQIYRF--------GATADTGAEMMANFSADFGQTPGDDFWEAFVESPLAPSCPLAQALLALEYHIVGCTADKRAAFVNAVGDLVSIRQLFLHLLRRWSSEYGWVKLTLMEKSDQTQKS-LFEKEESQIKHEWEDWVSESLA 685 HSP 2 Score: 76.2554 bits (186), Expect = 1.153e-34 Identity = 49/146 (33.56%), Postives = 72/146 (49.32%), Query Frame = 1 Query: 1966 LLVLSRNGLPLDIILSCLDKLGYVKDFEVVESDVWSLFHLTREIILKFHNEKFKLTHSICKEIVEHAFLAIASCSSVEARTRECQEYMYIDKRCKFHLLLAYHFWNQRNANLENISECVYHLDRGSDYESMETVLFLPRTLLGLFN 2403 L+ LSR GL L ILS L +LGY +V D W F + L+ + ++K H EIVEH F + + ++VE R + + R KFH LL +HF + + +E +YH DR S +E + +L P L +F Sbjct: 686 LIALSRRGLCLQGILSLLGRLGYSSQAQVALFD-WHRFFNSAAGTLQLVDGRYKFIHMHFAEIVEHIFFSCVAPAAVETRCKPSRLPTASGLRYKFHSLLGHHFLEEGDH-----AEAIYHFDRASQFEKLMEILSDPYVFLDVFG 825
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Nematostella
Match: EDO45428 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT98]) HSP 1 Score: 79.337 bits (194), Expect = 1.488e-14 Identity = 115/514 (22.37%), Postives = 202/514 (39.30%), Query Frame = 2 Query: 140 PFIISSGDDFTYELNAIKNEIFPSVKSYYFPKKHFSVNCFDLIYPNPKPMDILSNPLKDFVSINLDSIKQNGSISICLLGENFE-RLPKLYEDIGYDYPEFLENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGG---PISDDDDGNENEIESKQPSSEND----RMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFERFPDKISXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNP--EARIDELLNDFYRKDF---------SDKLSV------TIRRLNERTLSHI-------STSYQDN--KILVLTGSRGSGKSSILINWL-QSKTKNTDVICIPYYCEASYASSDLQKMLNSLIKRIRLD-CGYNLEQDDYETYSLETEMLSLSQKFLGAMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEV 1573 PF+ + DF E + + + +FP + ++ S DL + + + + L+ + LD++++ ICLLG+ + P E E+L + ++A GY W+ + SS+ E+ + Y FYFR I D E EI E++ ++ LKQ +I LP++ + + E D + N+LY+ + + + TN+ P + + E +++ YR+ F SD LSV + R LSH+ S D+ IL L G RGSGKS+++ WL Q T +V+ +P++ +S+D+ + + +R G +L +D + T+ +++ F A+ L ++ G H Q K W+P+ IPE R+IIT+ SD + +K +R D IE+ Sbjct: 23 PFVCGTFRDFHAERDFLNDHVFPKLHR-LCQERGTSFLPVDLRWDSKQGQSASDHILR----VCLDNVERCAPYFICLLGDRYGVHRPSESEPPDVATEEWLTKNYELATSHGYEWLKE-DEYRCSSLTELEVVQASFRKKYDYGYFYFRDPEHLKEKIDSADSEEEKEILLSNHKIESEYSAKKLRELKQQVIDTELPVRHFRTLEELGDLVLADWTSV-----------------------------------------INTLYSPIEPFVFSNTNTEPFRQWSLHETVSESYRRTFIRTPRTREISDVLSVHAEVEQGVTRKTSVALSHVMLSTFMTSVPGGDSLPPILTLLGERGSGKSALVSYWLKQFTTARPEVVLVPHHVGCDSSSADVTNFMRRCTRELRTQYLGSDL--NDIIDNNDITDFRRVTEAFHAAIELGPSVIVLDGASEFGKSHD-----LPAYQAKELTWLPKEIPEFCRLIITTIKSDITYRALK-QRKDSYFIEL 481
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Planmine SMEST
Match: SMESG000012448.1 (SMESG000012448.1) HSP 1 Score: 1238.4 bits (3203), Expect = 0.000e+0 Identity = 633/644 (98.29%), Postives = 638/644 (99.07%), Query Frame = 1 Query: 1966 LLVLSRNGLPLDIILSCLDKLGYVKDFEVVESDVWSLFHLTREIILKFHNEKFKLTHSICKEIVEHAFLAIASCSSVEARTRECQEYMYIDKRCKFHLLLAYHFWNQRNANLENISECVYHLDRGSDYESMETVLFLPRTLLGLFNLDASQLTNWHGQLTNTHYFQYYKNILSSKGCDFVNHILNLLNTXXXXXXXXXXXXXXXGPDGNDQKLVKLQYQKSVPYQSDFTKRFKIHVDRDEERESWLTLDQAQRNHFMLFLGRICELMDQMALARKIFNYLEDTLDDKVLLCSILWFDISLDSSLQTIFRNEDYILLVXXXXXXXXXXXXXXXWFDGSTENDTIKYIRSMCLILKCSIGAKTINEIYSPSEYHELRILSESFNSVILNCLVKEMNFNSMGETKDVKITQQKILMLSNIIILLETWTGPAHSHMARLFVKLSRLFEHGNSQLRFKAEACCRRALWIWKYMNKNKTNDYNSEENECREILFQFLIKDPCKSSIIEAKNQIYLTFDSRMKYLGCYHPLTVNLVPSIKLVNNLSDRSRYLLKPDSKILLSNSSKRSIPGSSSFTRNQSNLRVNRSVIDTIGKSRSAESNKVNDHRISESYGSSLQFINRYSKSADGFSEDIDWNEIAHSSSTSLMSRFS 3897 LLVLSRNGLPLDIILSCLDKLGYVKDFEVVESDVWSLFHLTREIILKFHNEKFK THSICKEIVEHAFLAIASCSSVEARTRECQEYMYIDKRCKFHLLLAYHFWNQRNANLENISECVYHLDRGSDYESMET+LFLPRTLLGLFNLDASQLTNWHGQLTNTHYFQYYKNILSSKGCDFVNHILNLLNTFY LEFDAAEAELEDG DGNDQKLVKLQYQKS+PYQSDFTKRFKIHVDRDEE+E+WLTL+QAQRNHFMLFLGRICEL DQMALARKIFNYLEDTLDDKVLLCSILWFDISLDSSLQTIFRNEDYILLVLNKLDDLTADLLKDDWFDGSTENDTIKYIRSMCLILKCSIGAKTINEIYSPSEYHELRILSESFNSVILNCLVKEMNFNSMGETKDVKITQQKILMLSNIIILLETWTGPAHSHMARLFVKLSRLFEHGNSQLRFKAEACCRRALWIWKYMNKNKTNDYNSEENECREILFQFLIKDPCKSSIIEAKNQIYLTFDSRMKYLGCYHPLTVNLVPSIKLVNNLSDRSRYLLKPDSKILLSNSSKRSI GSSSFTRNQSNLRVNRSVIDTIGKSRSA SNKVNDHRISESYGSSLQFINRYSKSADGFSEDIDWNEIAHSSSTSLMSRFS Sbjct: 620 LLVLSRNGLPLDIILSCLDKLGYVKDFEVVESDVWSLFHLTREIILKFHNEKFKFTHSICKEIVEHAFLAIASCSSVEARTRECQEYMYIDKRCKFHLLLAYHFWNQRNANLENISECVYHLDRGSDYESMETILFLPRTLLGLFNLDASQLTNWHGQLTNTHYFQYYKNILSSKGCDFVNHILNLLNTFYDLEFDAAEAELEDGLDGNDQKLVKLQYQKSIPYQSDFTKRFKIHVDRDEEKETWLTLEQAQRNHFMLFLGRICELTDQMALARKIFNYLEDTLDDKVLLCSILWFDISLDSSLQTIFRNEDYILLVLNKLDDLTADLLKDDWFDGSTENDTIKYIRSMCLILKCSIGAKTINEIYSPSEYHELRILSESFNSVILNCLVKEMNFNSMGETKDVKITQQKILMLSNIIILLETWTGPAHSHMARLFVKLSRLFEHGNSQLRFKAEACCRRALWIWKYMNKNKTNDYNSEENECREILFQFLIKDPCKSSIIEAKNQIYLTFDSRMKYLGCYHPLTVNLVPSIKLVNNLSDRSRYLLKPDSKILLSNSSKRSITGSSSFTRNQSNLRVNRSVIDTIGKSRSAGSNKVNDHRISESYGSSLQFINRYSKSADGFSEDIDWNEIAHSSSTSLMSRFS 1263 HSP 2 Score: 1195.26 bits (3091), Expect = 0.000e+0 Identity = 615/619 (99.35%), Postives = 618/619 (99.84%), Query Frame = 2 Query: 110 MFHNIDYNNFPFIISSGDDFTYELNAIKNEIFPSVKSYYFPKKHFSVNCFDLIYPNPKPMDILSNPLKDFVSINLDSIKQNGSISICLLGENFERLPKLYEDIGYDYPEFLENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPISDDDDGNENEIESKQPSSENDRMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFERFPDKISXXXXXXXXXXXXAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLNDFYRKDFSDKLSVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQSKTKNTDVICIPYYCEASYASSDLQKMLNSLIKRIRLDCGYNLEQDDYETYSLETEMLSLSQKFLGAMLLAKNXXXXXXXXXXXXXXXXXKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEVLPGSIDEQNELIKSGIDGLKTWISKHGQVYPSNFPQPIYSWPLIANPLIQKILARVYHTLGTTVKWKSFIEKASECQTLVELVRRVLKFHIYHINWELTVKSDKLKKNYIVNKEEEMEERSIQGWVPDCLS 1966 MFHNIDYNNFPFIISSGDDFTYELNAIKNEIFPSVKSYYFPKKHFSVNCFDLIYPNPKPMDILSNPLKDFVSINLDSIKQNGSISICLLGENFERLPKLY+DIGYD+PEFLENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPISDDDDGNENEIESKQ SSENDRMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFERFPDKISDQDDMFIDQQIFAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELL+DFYRKDFSDKLSVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQSKTKNTDVICIPYYCEASYASSDLQKMLNSLIKRIRLDCGYNLEQDDYETYSLETEMLSLSQKFLGAMLLAKNIGHRLLIIIDGIDHLGDKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEVLPGSIDEQNELIKSGIDGLKTWISKHGQVYPSNFPQPIYSWPLIANPLIQKILARVYHTLGTTVKWKSFIEKASECQTLVELVRRVLKFHIYHINWELTVKSDKLKKNYIVNKEEEMEERSIQGWVPDCLS Sbjct: 1 MFHNIDYNNFPFIISSGDDFTYELNAIKNEIFPSVKSYYFPKKHFSVNCFDLIYPNPKPMDILSNPLKDFVSINLDSIKQNGSISICLLGENFERLPKLYKDIGYDFPEFLENSLQIAADSGYPWIYNMNNNDRSSMLEVLSFYNGLLSEIKYPLFYFRVSGGPISDDDDGNENEIESKQASSENDRMENLKQILIRQGLPIKFYGSASEFNKAFRKDLMDIFERFPDKISDQDDMFIDQQIFAKDRLQMFTFNENIKKIFSEFNSLYTSLTKWTLNETNSNPEARIDELLSDFYRKDFSDKLSVTIRRLNERTLSHISTSYQDNKILVLTGSRGSGKSSILINWLQSKTKNTDVICIPYYCEASYASSDLQKMLNSLIKRIRLDCGYNLEQDDYETYSLETEMLSLSQKFLGAMLLAKNIGHRLLIIIDGIDHLGDKCAFSTKQIKSTDWIPEVIPENVRIIITSTASDSSLAQIKFKRTDIAIIEVLPGSIDEQNELIKSGIDGLKTWISKHGQVYPSNFPQPIYSWPLIANPLIQKILARVYHTLGTTVKWKSFIEKASECQTLVELVRRVLKFHIYHINWELTVKSDKLKKNYIVNKEEEMEERSIQGWVPDCLS 619 HSP 3 Score: 258.84 bits (660), Expect = 3.037e-69 Identity = 125/127 (98.43%), Postives = 127/127 (100.00%), Query Frame = 2 Query: 5645 VSRIQSAALNNHSSISVNLPSTPVRSQSVIVGNDVPSHIYFGPNSSLRSLCSPNAEDHNRASGSRNGKQVRFINLTKSGKGKFIQTEMAKMIQQKVQEMKLFGDTININQRRSVSTNFSRPYSNTTD 6025 VSRIQSAALNNHSSISVNLPSTPVRSQSVIVGNDVPSHIYFGPNSSLRSLCSP+AE+HNRASGSRNGKQVRFINLTKSGKGKFIQTEMAKMIQQKVQEMKLFGDTININQRRSVSTNFSRPYSNTTD Sbjct: 1264 VSRIQSAALNNHSSISVNLPSTPVRSQSVIVGNDVPSHIYFGPNSSLRSLCSPSAENHNRASGSRNGKQVRFINLTKSGKGKFIQTEMAKMIQQKVQEMKLFGDTININQRRSVSTNFSRPYSNTTD 1390 The following BLAST results are available for this feature:
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 3
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of TPR repeat-containing protein DDB_G0287407 isoform X2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008115 ID=SMED30008115|Name=TPR repeat-containing protein DDB_G0287407 isoform X2|organism=Schmidtea mediterranea sexual|type=transcript|length=6122bpback to top protein sequence of SMED30008115-orf-1 >SMED30008115-orf-1 ID=SMED30008115-orf-1|Name=SMED30008115-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=632bp MFHNIDYNNFPFIISSGDDFTYELNAIKNEIFPSVKSYYFPKKHFSVNCFback to top protein sequence of SMED30008115-orf-2 >SMED30008115-orf-2 ID=SMED30008115-orf-2|Name=SMED30008115-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=564bp MYIDKRCKFHLLLAYHFWNQRNANLENISECVYHLDRGSDYESMETVLFLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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