Malate dehydrogenase 1B
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008051 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Malate dehydrogenase 1B vs. Ensembl Human
Match: MDH1B (malate dehydrogenase 1B [Source:HGNC Symbol;Acc:HGNC:17836]) HSP 1 Score: 267.314 bits (682), Expect = 3.655e-81 Identity = 167/465 (35.91%), Postives = 260/465 (55.91%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 MAK V+AG +DCPY+AK EL+AD L+ N+P+F +HKI + + W W ++C+ N WS K+SPIIWREL+DRGGKG L+GG NEF E+ + YY+V S T+ M IA +N+ +++E K P +V I A A + + L+ G+V +TE++I D + LKSL + T DLA ++RS+SI E AF + ++V+ DD E +++ G IEK V+V+ + +++N+ + + R RI N++ ++ VE + ++++ARKL PS + + I+WGNI G Y+D +RV+RY+ A+ GP +S V ++D +W+K E ++ N ++ G LA A +I T L W +G G I SL I SEG +G+P G+ FSMPV G W V+ D++ EI + + D+I++ Sbjct: 1 MAKFVIAGRADCPYYAKTELVADYLQKNLPDFRIHKITQRPEVWEDWLKDVCEKNKWSHKNSPIIWRELLDRGGKGLLLGGYNEFLEHAQLYYDVTSSMTTELMMVIAQENLGAHIEKEQEEEALKTCINPLQVWITSASAPACYNLIPILTSGEVFGMHTEISITLFDNKQAEEHLKSLVVETQDLASPVLRSVSICTKVEEAFRQAHVIVVLDDSTNKEVFTLE--DCLRSRVPLCRLYGYLIEKNAHESVRVI---VGGRTFVNLKTVLLMRYAPRIAH-NIIAVALGVEGEAKAILARKLKTAPSYIKDVIIWGNISGNNYVDLRKTRVYRYESAIWGPLHYSRPVLNLIFDSEWVKREFVAILKN----LTTTGRQFGGILA-AHSIATTLKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPVKFE-NGTWVVLTDLKDVEISEQIMTRMTSDLIQE 453
BLAST of Malate dehydrogenase 1B vs. Ensembl Human
Match: MDH1B (malate dehydrogenase 1B [Source:HGNC Symbol;Acc:HGNC:17836]) HSP 1 Score: 266.929 bits (681), Expect = 4.879e-81 Identity = 167/465 (35.91%), Postives = 260/465 (55.91%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 MAK V+AG +DCPY+AK EL+AD L+ N+P+F +HKI + + W W ++C+ N WS K+SPIIWREL+DRGGKG L+GG NEF E+ + YY+V S T+ M IA +N+ +++E K P +V I A A + + L+ G+V +TE++I D + LKSL + T DLA ++RS+SI E AF + ++V+ DD E +++ G IEK V+V+ + +++N+ + + R RI N++ ++ VE + ++++ARKL PS + + I+WGNI G Y+D +RV+RY+ A+ GP +S V ++D +W+K E ++ N ++ G LA A +I T L W +G G I SL I SEG +G+P G+ FSMPV G W V+ D++ EI + + D+I++ Sbjct: 1 MAKFVIAGRADCPYYAKTELVADYLQKNLPDFRIHKITQRPEVWEDWLKDVCEKNKWSHKNSPIIWRELLDRGGKGLLLGGYNEFLEHAQLYYDVTSSMTTELMMVIAQENLGAHIEKEQEEEALKTCINPLQVWITSASAPACYNLIPILTSGEVFGMHTEISITLFDNKQAEEHLKSLVVETQDLASPVLRSVSICTKVEEAFRQAHVIVVLDDSTNKEVFTLE--DCLRSRVPLCRLYGYLIEKNAHESVRVI---VGGRTFVNLKTVLLMRYAPRIAH-NIIAVALGVEGEAKAILARKLKTAPSYIKDVIIWGNISGNNYVDLRKTRVYRYESAIWGPLHYSRPVLNLIFDSEWVKREFVAILKN----LTTTGRQFGGILA-AHSIATTLKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPVKFE-NGTWVVLTDLKDVEISEQIMTRMTSDLIQE 453
BLAST of Malate dehydrogenase 1B vs. Ensembl Human
Match: MDH1B (malate dehydrogenase 1B [Source:HGNC Symbol;Acc:HGNC:17836]) HSP 1 Score: 171.4 bits (433), Expect = 1.915e-46 Identity = 112/367 (30.52%), Postives = 186/367 (50.68%), Query Frame = 2 Query: 332 FTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 T+ M IA +N+ +++E K P +V I A A + + L+ G+V +TE++I D + LKSL + T DLA ++RS+SI E AF + ++V+ DD E +++ G IEK V+V+ + +++N+ + + R RI N++ ++ VE + ++++ARKL PS + + I+WGNI G Y+D +RV+RY+ A+ GP +S V ++D +W+K E ++ N ++ G LA A +I T L W +G G I SL I SEG +G+P G+ FSMPV G W V+ D++ EI + + D+I++ Sbjct: 1 MTTELMMVIAQENLGAHIEKEQEEEALKTCINPLQVWITSASAPACYNLIPILTSGEVFGMHTEISITLFDNKQAEEHLKSLVVETQDLASPVLRSVSICTKVEEAFRQAHVIVVLDDSTNKEVFTLE--DCLRSRVPLCRLYGYLIEKNAHESVRVI---VGGRTFVNLKTVLLMRYAPRIAH-NIIAVALGVEGEAKAILARKLKTAPSYIKDVIIWGNISGNNYVDLRKTRVYRYESAIWGPLHYSRPVLNLIFDSEWVKREFVAILKN----LTTTGRQFGGILA-AHSIATTLKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPVKFE-NGTWVVLTDLKDVEISEQIMTRMTSDLIQE 355
BLAST of Malate dehydrogenase 1B vs. Ensembl Human
Match: MDH1B (malate dehydrogenase 1B [Source:HGNC Symbol;Acc:HGNC:17836]) HSP 1 Score: 108.612 bits (270), Expect = 2.832e-27 Identity = 63/133 (47.37%), Postives = 89/133 (66.92%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTK 436 MAK V+AG +DCPY+AK EL+AD L+ N+P+F +HKI + + W W ++C+ N WS K+SPIIWREL+DRGGKG L+GG NEF E+ + YY+V S T+ M IA +N+ +++E K P + Sbjct: 1 MAKFVIAGRADCPYYAKTELVADYLQKNLPDFRIHKITQRPEVWEDWLKDVCEKNKWSHKNSPIIWRELLDRGGKGLLLGGYNEFLEHAQLYYDVTSSMTTELMMVIAQENLGAHIEKEQEEEALKTCINPLQ 133
BLAST of Malate dehydrogenase 1B vs. Ensembl Human
Match: MDH1B (malate dehydrogenase 1B [Source:HGNC Symbol;Acc:HGNC:17836]) HSP 1 Score: 111.694 bits (278), Expect = 1.287e-26 Identity = 65/136 (47.79%), Postives = 91/136 (66.91%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVI 445 MAK V+AG +DCPY+AK EL+AD L+ N+P+F +HKI + + W W ++C+ N WS K+SPIIWREL+DRGGKG L+GG NEF E+ + YY+V S T+ M IA +N+ +++E K P +V I Sbjct: 1 MAKFVIAGRADCPYYAKTELVADYLQKNLPDFRIHKITQRPEVWEDWLKDVCEKNKWSHKNSPIIWRELLDRGGKGLLLGGYNEFLEHAQLYYDVTSSMTTELMMVIAQENLGAHIEKEQEEEALKTCINPLQVWI 136 HSP 2 Score: 57.7658 bits (138), Expect = 1.776e-8 Identity = 39/113 (34.51%), Postives = 58/113 (51.33%), Query Frame = 2 Query: 1097 VW-DKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 VW +W+K E ++ N ++ G LA A +I T L W +G G I SL I SEG +G+P G+ FSMPV G W V+ D++ EI + + D+I++ Sbjct: 134 VWITSEWVKREFVAILKN----LTTTGRQFGGILA-AHSIATTLKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPVKFE-NGTWVVLTDLKDVEISEQIMTRMTSDLIQE 240
BLAST of Malate dehydrogenase 1B vs. Ensembl Celegans
Match: mdh-1 (Malate dehydrogenase [Source:UniProtKB/TrEMBL;Acc:Q8IA49]) HSP 1 Score: 76.2554 bits (186), Expect = 8.481e-15 Identity = 79/341 (23.17%), Postives = 145/341 (42.52%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFA--DSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNIN-LISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 +S P +V++ GA + V+ ++ G V + +V +D + IL+ + D A + S+ + ++AF D + +V R D + AN + ++ G + +Y KV++V A N N I+ +IP N ++R + + +A K NV N I+WGN G + D ++ V++ G E + + V D +L+ + R I + L + ++ A A + W G + G S+ + S+G YG+P G+ FS PVT+ G W +VQ + + I +++ E+ Sbjct: 1 MSAPLRVLVTGAAGQIGYSIVIRIADGTVFGKEQPVELVLLDVPQCSNILEGVVFELQDCALPTLFSVVAVTDEKSAFTGIDYAFLVGAMPRREGMERKD----LLAANVKIFKSQGKALAEYAKPTTKVIVVGNPA----NTNAFIAAKYAAGKIPAKNFSAMTRLDHNRALAQLALKTGTTIGNVKNVIIWGNHSGTQFPDVTHATVNKN-----GTETDAYA---AVGDNAFLQGPFIATVQKRGGVIIEKRK-LSSAMSAAKAACDHIHDWHFGTKAGQFVSMAVPSDGSYGIPQGLIFSFPVTIE-GGEWKIVQGLSFDDFAKGKIAATTKELEEE 323
BLAST of Malate dehydrogenase 1B vs. Ensembl Celegans
Match: mdh-1 (Malate dehydrogenase [Source:UniProtKB/TrEMBL;Acc:Q8IA49]) HSP 1 Score: 51.9878 bits (123), Expect = 1.934e-7 Identity = 44/178 (24.72%), Postives = 79/178 (44.38%), Query Frame = 2 Query: 899 LSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 ++R + + +A K NV N I+WGN G + D ++ V++ G E + + V D +L+ + R I + L + ++ A A + W G + G S+ + S+G YG+P G+ FS PVT+ G W +VQ + + I +++ E+ Sbjct: 1 MTRLDHNRALAQLALKTGTTIGNVKNVIIWGNHSGTQFPDVTHATVNKN-----GTETDAYA---AVGDNAFLQGPFIATVQKRGGVIIE-KRKLSSAMSAAKAACDHIHDWHFGTKAGQFVSMAVPSDGSYGIPQGLIFSFPVTIE-GGEWKIVQGLSFDDFAKGKIAATTKELEEE 168
BLAST of Malate dehydrogenase 1B vs. Ensembl Celegans
Match: mdh-1 (Malate dehydrogenase [Source:UniProtKB/TrEMBL;Acc:Q8IA49]) HSP 1 Score: 50.8322 bits (120), Expect = 1.264e-6 Identity = 48/211 (22.75%), Postives = 90/211 (42.65%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFA--DSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNIN-LISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHR 1042 +S P +V++ GA + V+ ++ G V + +V +D + IL+ + D A + S+ + ++AF D + +V R D + AN + ++ G + +Y KV++V A N N I+ +IP N ++R + + +A K NV N I+WGN G + D ++ V++ Sbjct: 1 MSAPLRVLVTGAAGQIGYSIVIRIADGTVFGKEQPVELVLLDVPQCSNILEGVVFELQDCALPTLFSVVAVTDEKSAFTGIDYAFLVGAMPRREGMERKD----LLAANVKIFKSQGKALAEYAKPTTKVIVVGNPA----NTNAFIAAKYAAGKIPAKNFSAMTRLDHNRALAQLALKTGTTIGNVKNVIIWGNHSGTQFPDVTHATVNK 203
BLAST of Malate dehydrogenase 1B vs. Ensembl Fly
Match: Mdh1 (gene:FBgn0262782 transcript:FBtr0345435) HSP 1 Score: 78.9518 bits (193), Expect = 1.424e-15 Identity = 77/322 (23.91%), Postives = 136/322 (42.24%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSE 1384 ++ P +VV+ GA + + ++RG+V + + + +D + +L+ + M D A L+ + T + F D S + + E + AN + + G ++K+ DVKVL+V A N N + IP+ N ++R + + S +A KL V S V N I+WGN Y D ++V +G V SV + D +L+ + R + + + ++ A A + W NG G S+ + S+G Y P + FS PV + + W +V + LS+ Sbjct: 1 MAEPIRVVVTGAAGQIAYSLLYMIARGEVFGKDQPIVLHLLDIPPMVGVLEGVVMELADCALPLLVEVVPTTDPAVGFKDVSAAFLVGAM--PRKEGMERKDLLSANVKIFRTQGQALDKFAKKDVKVLVVGNPA----NTNALVCSSYAPSIPRENFSAMTRLDQNRATSQIAAKLGVPISAVKNIIIWGNHSSTQYPDAGQAKV-TANGTVK-------SVVDAINDNGYLQGSFVETVQKRGAAVIAARK-MSSAMSAAKAACDHMHDWWNGTAPGQFVSMGVFSDGSYDSPKDVIFSFPVEIKNK-QWKIVSGLTLSD 306
BLAST of Malate dehydrogenase 1B vs. Ensembl Fly
Match: Mdh1 (gene:FBgn0262782 transcript:FBtr0080050) HSP 1 Score: 78.9518 bits (193), Expect = 1.424e-15 Identity = 77/322 (23.91%), Postives = 136/322 (42.24%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSE 1384 ++ P +VV+ GA + + ++RG+V + + + +D + +L+ + M D A L+ + T + F D S + + E + AN + + G ++K+ DVKVL+V A N N + IP+ N ++R + + S +A KL V S V N I+WGN Y D ++V +G V SV + D +L+ + R + + + ++ A A + W NG G S+ + S+G Y P + FS PV + + W +V + LS+ Sbjct: 1 MAEPIRVVVTGAAGQIAYSLLYMIARGEVFGKDQPIVLHLLDIPPMVGVLEGVVMELADCALPLLVEVVPTTDPAVGFKDVSAAFLVGAM--PRKEGMERKDLLSANVKIFRTQGQALDKFAKKDVKVLVVGNPA----NTNALVCSSYAPSIPRENFSAMTRLDQNRATSQIAAKLGVPISAVKNIIIWGNHSSTQYPDAGQAKV-TANGTVK-------SVVDAINDNGYLQGSFVETVQKRGAAVIAARK-MSSAMSAAKAACDHMHDWWNGTAPGQFVSMGVFSDGSYDSPKDVIFSFPVEIKNK-QWKIVSGLTLSD 306
BLAST of Malate dehydrogenase 1B vs. Ensembl Zebrafish
Match: mdh1b (malate dehydrogenase 1B, NAD (soluble) [Source:NCBI gene;Acc:767794]) HSP 1 Score: 251.136 bits (640), Expect = 5.512e-76 Identity = 152/463 (32.83%), Postives = 242/463 (52.27%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKE-NEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDI 1423 MAK V+AG +DCPY+AK ELLAD L+ N+P+FH+HKI +W W + C + W SP++WREL+DRGGKG L+GG ++F E+ + YYN+ SD S M IA +N KE ++E+ K+L P + I A+N + L + + ++ +D + +L++L+M T DLA + + N D++N D D+ E++ G IE DV+VL + ++N+ + I N V ++ +E + R+ +A+KL+V S++ N IVWGNI G +ID ++V RYDGA+ GP+ FS V + ++D KWLK + L+ IS N T ++ +AI L W N + + SL + S G +G+P G+ FSMPV+ G+W+V DV +++ +++ C ++ Sbjct: 8 MAKFVLAGKADCPYYAKAELLADVLQRNLPDFHIHKIPVPPDDWKKWLEDTCASIGWKHSSSPLVWRELIDRGGKGMLLGGFSDFLEHAQGYYNITSDMNSDLMLKIAEENQATKELCMEEEVHRLKSLR-PLHIWISSALNPVCYSLIPHLFTPGLFSGLPIFSLHLMDTSGSEEMLQALKMETVDLAIPRLHEPAGEYN--------------DEQN----DKDQV-------AEHFHRYGQLIETNAQKDVRVL---VAGDFFINMKCSLLIENAPSIDPRNFVAMTTQLEYEARTQLAQKLSVKTSDITNVIVWGNISGSFHIDLQRAKVFRYDGAIRGPDGFSQHVMEMIYDWKWLKTDFRSLLHKHRATISSKTNK-ATAISTTNAILAILKAWNNAESPEEVFSLGVLSTGQFGIPAGLVFSMPVSFT-DGHWSVRSDVIVTDELRVNLDACADEL 439
BLAST of Malate dehydrogenase 1B vs. Ensembl Zebrafish
Match: mdh1aa (malate dehydrogenase 1Aa, NAD (soluble) [Source:ZFIN;Acc:ZDB-GENE-040204-1]) HSP 1 Score: 111.694 bits (278), Expect = 2.271e-26 Identity = 92/345 (26.67%), Postives = 155/345 (44.93%), Query Frame = 2 Query: 401 IREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEG-WYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 +R A + P +V++ GA + + S+++GDV + + +V +D T LP+L + M D A L+R + TD E F D ++ + + E +KAN ++ G +EKY VKVL+V A N N + + IPK N L+R + RS VA ++ V +V N +WGN Y D +++ V R G E ++ V D+ WLK + + R + L + ++ A AI + G G S+ I S G YGVPD + +S PV + + W VV + +++ ++ +++E+ Sbjct: 12 VRTASAQAEPIRVLVTGAAGQIAYSLLYSIAKGDVFGKDQPIILVLLDITPMLPVLDGVVMELQDCALPLLREVIPTDKVEVGFKDLDAAILVG--SMPRKEGMERKDLLKANVAIFKTQGEALEKYAKKTVKVLVVGNPA----NTNCLIASKSAPSIPKENFSCLTRLDHNRARSQVAMRVGVPSDSVKNVTIWGNHSSTQYPDVHHAIVTRN-----GKE---IAAFDAVNDESWLKGDFISTVQQRGAAVIKARK-LSSAMSAAKAICDHMRDIWFGTPDGEWVSMGIYSSGNSYGVPDDLMYSFPVKIKNKS-WKVVDGLSINDFSRGKMDATAAELVEE 340
BLAST of Malate dehydrogenase 1B vs. Ensembl Zebrafish
Match: mdh1ab (malate dehydrogenase 1Ab, NAD (soluble) [Source:ZFIN;Acc:ZDB-GENE-030131-7655]) HSP 1 Score: 110.923 bits (276), Expect = 3.270e-26 Identity = 85/338 (25.15%), Postives = 153/338 (45.27%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 +S P +V++ GA + + +++GDV + L ++ +D T LP+L+ + M D A L+R + TD + AF D ++ + E +KAN ++ G ++KY VKVL+V A N N + + IPK N L+R + S VA + + P+NV N I+WGN Y D ++ +V+ V G + + K D WLK E + R + L + ++ A AI + W E +I V ++ YGVP+ + +S P+++ + W +V + +++ + +++E+ Sbjct: 1 MSEPIRVLVTGAAGQIAYSLLYGIAKGDVFGKDQPLVLLLLDITPMLPVLEGVVMELQDCALPLLREVIPTDKEDVAFKDLDAAILVGSMPRR--EGMERKDLLKANVAIFKSQGEALDKYAKKTVKVLVVGNPA----NTNCLIAAKSAPSIPKENFSCLTRLDHNRASSQVALRCGIAPNNVKNVIIWGNHSSTQYPDVHHCKVN-----VQGKDETAFDAVK---DDAWLKGEFISTVQQRGAAVIKARK-LSSAMSAAKAI*QDI--WTGTPEGEFISMGVYSTGNSYGVPEDLIYSFPISIKDKN-WKIVDGLPINDFSKAKMEATAAELVEE 320
BLAST of Malate dehydrogenase 1B vs. Ensembl Zebrafish
Match: mdh1aa (malate dehydrogenase 1Aa, NAD (soluble) [Source:ZFIN;Acc:ZDB-GENE-040204-1]) HSP 1 Score: 110.153 bits (274), Expect = 6.256e-26 Identity = 90/339 (26.55%), Postives = 153/339 (45.13%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEG-WYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 ++ P +V++ GA + + S+++GDV + + +V +D T LP+L + M D A L+R + TD E F D ++ + + E +KAN ++ G +EKY VKVL+V A N N + + IPK N L+R + RS VA ++ V +V N +WGN Y D +++ V R G E ++ V D+ WLK + + R + L + ++ A AI + G G S+ I S G YGVPD + +S PV + + W VV + +++ ++ +++E+ Sbjct: 1 MAEPIRVLVTGAAGQIAYSLLYSIAKGDVFGKDQPIILVLLDITPMLPVLDGVVMELQDCALPLLREVIPTDKVEVGFKDLDAAILVG--SMPRKEGMERKDLLKANVAIFKTQGEALEKYAKKTVKVLVVGNPA----NTNCLIASKSAPSIPKENFSCLTRLDHNRARSQVAMRVGVPSDSVKNVTIWGNHSSTQYPDVHHAIVTRN-----GKE---IAAFDAVNDESWLKGDFISTVQQRGAAVIKARK-LSSAMSAAKAICDHMRDIWFGTPDGEWVSMGIYSSGNSYGVPDDLMYSFPVKIKNKS-WKVVDGLSINDFSRGKMDATAAELVEE 323
BLAST of Malate dehydrogenase 1B vs. Ensembl Zebrafish
Match: mdh1aa (malate dehydrogenase 1Aa, NAD (soluble) [Source:ZFIN;Acc:ZDB-GENE-040204-1]) HSP 1 Score: 52.7582 bits (125), Expect = 3.820e-8 Identity = 26/86 (30.23%), Postives = 44/86 (51.16%), Query Frame = 2 Query: 401 IREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFAD 658 +R A + P +V++ GA + + S+++GDV + + +V +D T LP+L + M D A L+R + TD E F D Sbjct: 12 VRTASAQAEPIRVLVTGAAGQIAYSLLYSIAKGDVFGKDQPIILVLLDITPMLPVLDGVVMELQDCALPLLREVIPTDKVEVGFKD 97
BLAST of Malate dehydrogenase 1B vs. Ensembl Xenopus
Match: MDH1B (malate dehydrogenase 1B [Source:NCBI gene;Acc:100490547]) HSP 1 Score: 249.595 bits (636), Expect = 6.831e-74 Identity = 165/465 (35.48%), Postives = 253/465 (54.41%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDV----ELSEIQFKSINECIQD 1420 MAK V+AG +DCPY+AK E+LA+ L+ N+P+F VHKI + ++W W ++C N WS SPIIWREL+DRGGKG L+GG N+F E+ + YYN+ +D SS M+DIAL+N+R KE E L P V I A + + L+ G+V E+ + ++ + L++L M DLA+ L+R I++ + AF + V++ DD + E +K E G I++ +VKV+ + +Y+N+ I + NVV L+ +E + R+ +A+KLN+N + V + I+WGNI G ++D ++++++YD AV GP+ F + K ++D+KWLKNE +R Q N LG ++ A +I L W G I SL I SEG + +P G+ +SMPV G W V V E E F++ E I++ Sbjct: 13 MAKFVLAGKADCPYYAKAEILAEYLQKNLPSFRVHKITQHPEDWEEWLQKICMQNGWSHNHSPIIWRELLDRGGKGLLLGGFNDFFEHAQEYYNITTDMMSSLMKDIALENLRTHMEIKKEQEEICCLFNPLHVWITSATTPTCYNLISLLASGEVFGMRKEIWLHLLETSHCNGTLRALVMEAEDLAFPLLRKITVHKMADDAFLQADFVIVLDDVYVTNDQSPEIC--IKQIAERCLQYGALIDQNSDKEVKVV---VAGSTYVNLKAQMILSNAPSVKPHNVVALATQLEYEARAQIAKKLNINSAVVKDVILWGNISGTNFLDLQHAKIYQYDSAVWGPQGFWRPLKKMIFDRKWLKNEFLKEWRSRQQ------NRLG--MSAAHSIAMVLSWWQQESNTGDIVSLGIISEGQFELPKGIVYSMPVQF-INGEWQVYTKVTVLDETKETLFQAARELIKE 463
BLAST of Malate dehydrogenase 1B vs. Ensembl Xenopus
Match: mdh1 (malate dehydrogenase 1 [Source:NCBI gene;Acc:448318]) HSP 1 Score: 103.605 bits (257), Expect = 1.911e-23 Identity = 83/350 (23.71%), Postives = 160/350 (45.71%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDD--RNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEG-WYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRIIYPWIN 1459 L P KV++ GA + + +++GDV + L +V +D T + +L+ + M D A L++ + TD + AF D + ++ R D +KAN + ++ G + KY VKV++V A N N ++ + IPK N L+R + + +A KLNV +V N I+WGN Y D +++ V+ + G + + K + WLK E + R + L + ++ A AI + G G S+ + S+G YG+P+ + +S P+T+ + W +V+ + +++ + ++ +++ E+ +++ Sbjct: 7 LPEPVKVLVTGAAGQIAYSLLYGIAKGDVFGKDQPLILVLLDITPMMTVLEGVVMELQDCALPLLKEVIATDKEDVAFKDLDVAILVGSMPRREGMERKD----LLKANVKIFKSQGAALNKYSKKSVKVIVVGNPA----NTNCLTAMKSAPSIPKENFSCLTRLDHNRAKGQIALKLNVASDDVKNVIIWGNHSSTQYPDASHATVN-----LQGKDVGAFEAVK---NDDWLKGEFITTVQQRGAAVIKARK-LSSAMSAAKAICDHVRDIWFGTPDGQFVSMGVISDGNSYGIPEDLMYSFPLTIKNK-TWKIVEGLPINDFSREKMDLTAKELHEEKETALEFLS 338
BLAST of Malate dehydrogenase 1B vs. Ensembl Xenopus
Match: mdh1 (malate dehydrogenase 1 [Source:NCBI gene;Acc:448318]) HSP 1 Score: 102.834 bits (255), Expect = 3.050e-23 Identity = 81/345 (23.48%), Postives = 159/345 (46.09%), Query Frame = 2 Query: 428 PTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEG-WYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRIIYPWIN 1459 P KV++ GA + + +++GDV + L +V +D T + +L+ + M D A L++ + TD + AF D + ++ + E +KAN + ++ G + KY VKV++V A N N ++ + IPK N L+R + + +A KLNV +V N I+WGN Y D +++ V+ + G + + K + WLK E + R + L + ++ A AI + G G S+ + S+G YG+P+ + +S P+T+ + W +V+ + +++ + ++ +++ E+ +++ Sbjct: 4 PVKVLVTGAAGQIAYSLLYGIAKGDVFGKDQPLILVLLDITPMMTVLEGVVMELQDCALPLLKEVIATDKEDVAFKDLDVAILVGSM--PRREGMERKDLLKANVKIFKSQGAALNKYSKKSVKVIVVGNPA----NTNCLTAMKSAPSIPKENFSCLTRLDHNRAKGQIALKLNVASDDVKNVIIWGNHSSTQYPDASHATVN-----LQGKDVGAFEAVK---NDDWLKGEFITTVQQRGAAVIKARK-LSSAMSAAKAICDHVRDIWFGTPDGQFVSMGVISDGNSYGIPEDLMYSFPLTIKNK-TWKIVEGLPINDFSREKMDLTAKELHEEKETALEFLS 332
BLAST of Malate dehydrogenase 1B vs. Ensembl Xenopus
Match: mdh1 (malate dehydrogenase 1 [Source:NCBI gene;Acc:448318]) HSP 1 Score: 102.834 bits (255), Expect = 3.278e-23 Identity = 81/345 (23.48%), Postives = 159/345 (46.09%), Query Frame = 2 Query: 428 PTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEG-WYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRIIYPWIN 1459 P KV++ GA + + +++GDV + L +V +D T + +L+ + M D A L++ + TD + AF D + ++ + E +KAN + ++ G + KY VKV++V A N N ++ + IPK N L+R + + +A KLNV +V N I+WGN Y D +++ V+ + G + + K + WLK E + R + L + ++ A AI + G G S+ + S+G YG+P+ + +S P+T+ + W +V+ + +++ + ++ +++ E+ +++ Sbjct: 5 PVKVLVTGAAGQIAYSLLYGIAKGDVFGKDQPLILVLLDITPMMTVLEGVVMELQDCALPLLKEVIATDKEDVAFKDLDVAILVGSM--PRREGMERKDLLKANVKIFKSQGAALNKYSKKSVKVIVVGNPA----NTNCLTAMKSAPSIPKENFSCLTRLDHNRAKGQIALKLNVASDDVKNVIIWGNHSSTQYPDASHATVN-----LQGKDVGAFEAVK---NDDWLKGEFITTVQQRGAAVIKARK-LSSAMSAAKAICDHVRDIWFGTPDGQFVSMGVISDGNSYGIPEDLMYSFPLTIKNK-TWKIVEGLPINDFSREKMDLTAKELHEEKETALEFLS 333
BLAST of Malate dehydrogenase 1B vs. Ensembl Xenopus
Match: mdh1 (malate dehydrogenase 1 [Source:NCBI gene;Acc:448318]) HSP 1 Score: 102.449 bits (254), Expect = 5.673e-23 Identity = 82/338 (24.26%), Postives = 156/338 (46.15%), Query Frame = 2 Query: 428 PTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDD--RNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEG-WYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 P KV++ GA + + +++GDV + L +V +D T + +L+ + M D A L++ + TD + AF D + ++ R D +KAN + ++ G + KY VKV++V A N N ++ + IPK N L+R + + +A KLNV +V N I+WGN Y D +++ V+ + G + + K + WLK E + R + L + ++ A AI + G G S+ + S+G YG+P+ + +S P+T+ + W +V+ + +++ + ++ +++ E+ Sbjct: 20 PVKVLVTGAAGQIAYSLLYGIAKGDVFGKDQPLILVLLDITPMMTVLEGVVMELQDCALPLLKEVIATDKEDVAFKDLDVAILVGSMPRREGMERKD----LLKANVKIFKSQGAALNKYSKKSVKVIVVGNPA----NTNCLTAMKSAPSIPKENFSCLTRLDHNRAKGQIALKLNVASDDVKNVIIWGNHSSTQYPDASHATVN-----LQGKDVGAFEAVK---NDDWLKGEFITTVQQRGAAVIKARK-LSSAMSAAKAICDHVRDIWFGTPDGQFVSMGVISDGNSYGIPEDLMYSFPLTIKNK-TWKIVEGLPINDFSREKMDLTAKELHEE 339
BLAST of Malate dehydrogenase 1B vs. Ensembl Mouse
Match: Mdh1b (malate dehydrogenase 1B, NAD (soluble) [Source:MGI Symbol;Acc:MGI:1923918]) HSP 1 Score: 246.128 bits (627), Expect = 1.729e-73 Identity = 153/465 (32.90%), Postives = 252/465 (54.19%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 MAK V+AG ++CPY+AK ELLAD L+ N+P+F + KI + +W W ++C+ N W + SPIIWREL+DRGG+G L+GG NEF E+ + YY V S+ T+ M IA +N++ + + K L +P +V I A H + L G+V +TE+++ D+ + L+S+ M T DLA ++R++S + AF + +++I DD E +++ G IEK VKV+ + +++N+ + + I N++ ++ VE Q ++V+ARK+ +N+ + I+WGNI G Y+D ++V+ Y+ AV GP SV ++D++W+ E + + +S G LA A +I T L W +G G I SL + SEG + +P+G+ FSMPV G W V+ D+E + K+++ D+I++ Sbjct: 1 MAKFVIAGKANCPYYAKAELLADYLQKNLPDFRIFKITQHPDKWEDWVEDVCERNMWDHRTSPIIWRELLDRGGRGLLLGGYNEFLEHAQLYYGVTSNMTTELMMVIAKENMQTHTEQQLDKETMKDLISPLQVWIASAGTYVCCHLIPLLLSGEVFGMHTEISLTLFDQEQREDCLRSIVMETQDLASPVLRTVSFCTTVKEAFLQAQVIIILDDSTEEEVYSLESC--LRSRVPLCRLYGYLIEKNAHKSVKVI---VGGKNFVNLKTTLLMQYAPNIAS-NIIAVALGVEGQAKAVLARKMKTTSANIKDVIIWGNITGNNYVDLRKAKVYNYESAVKGPPGHYHSVLSLIFDREWITKEF----VQTLKILSSTGKQFGGILA-AHSIATTLKYWYHGSPPGEIVSLGVMSEGQFDIPEGIVFSMPVKFE-NGTWVVLTDLEDISLSEKTLSRLTGDLIQE 453
BLAST of Malate dehydrogenase 1B vs. Ensembl Mouse
Match: Mdh1 (malate dehydrogenase 1, NAD (soluble) [Source:MGI Symbol;Acc:MGI:97051]) HSP 1 Score: 115.161 bits (287), Expect = 1.739e-27 Identity = 88/352 (25.00%), Postives = 161/352 (45.74%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDD--RNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQ-WINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRIIYPWINNS 1465 +S P +V++ GA + + S+ G V + + +V +D T + +L + M D A L++ + TD E AF D + V+ R D +KAN + ++ G +EKY VKV++V A N N ++ + IPK N L+R + +S +A KL V +V N I+WGN Y D N+++V + G E + V + + D WLK E + R + L + ++ A AI + W E ++ VI+ YGVPD + +S PV + + W V+ + +++ + ++ +++ E+ + +++++ Sbjct: 1 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLQDVIATDKEEIAFKDLDVAVLVGSMPRREGMERKD----LLKANVKIFKSQGTALEKYAKKSVKVIVVGNPA----NTNCLTASKSAPSIPKENFSCLTRLDHNRAKSQIALKLGVTADDVKNVIIWGNHSSTQYPDVNHAKVK-----LQGKE---VGVYEALKDDSWLKGEFITTVQQRGAAVIKARK-LSSAMSAAKAIADHIRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNK-TWKFVEGLPINDFSREKMDLTAKELTEEKETAFEFLSSA 334
BLAST of Malate dehydrogenase 1B vs. Ensembl Mouse
Match: Mdh1 (malate dehydrogenase 1, NAD (soluble) [Source:MGI Symbol;Acc:MGI:97051]) HSP 1 Score: 114.775 bits (286), Expect = 1.951e-27 Identity = 88/352 (25.00%), Postives = 161/352 (45.74%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDD--RNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQ-WINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRIIYPWINNS 1465 +S P +V++ GA + + S+ G V + + +V +D T + +L + M D A L++ + TD E AF D + V+ R D +KAN + ++ G +EKY VKV++V A N N ++ + IPK N L+R + +S +A KL V +V N I+WGN Y D N+++V + G E + V + + D WLK E + R + L + ++ A AI + W E ++ VI+ YGVPD + +S PV + + W V+ + +++ + ++ +++ E+ + +++++ Sbjct: 1 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLQDVIATDKEEIAFKDLDVAVLVGSMPRREGMERKD----LLKANVKIFKSQGTALEKYAKKSVKVIVVGNPA----NTNCLTASKSAPSIPKENFSCLTRLDHNRAKSQIALKLGVTADDVKNVIIWGNHSSTQYPDVNHAKVK-----LQGKE---VGVYEALKDDSWLKGEFITTVQQRGAAVIKARK-LSSAMSAAKAIADHIRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNK-TWKFVEGLPINDFSREKMDLTAKELTEEKETAFEFLSSA 334
BLAST of Malate dehydrogenase 1B vs. Ensembl Mouse
Match: Mdh1 (malate dehydrogenase 1, NAD (soluble) [Source:MGI Symbol;Acc:MGI:97051]) HSP 1 Score: 114.775 bits (286), Expect = 1.951e-27 Identity = 88/352 (25.00%), Postives = 161/352 (45.74%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDD--RNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQ-WINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRIIYPWINNS 1465 +S P +V++ GA + + S+ G V + + +V +D T + +L + M D A L++ + TD E AF D + V+ R D +KAN + ++ G +EKY VKV++V A N N ++ + IPK N L+R + +S +A KL V +V N I+WGN Y D N+++V + G E + V + + D WLK E + R + L + ++ A AI + W E ++ VI+ YGVPD + +S PV + + W V+ + +++ + ++ +++ E+ + +++++ Sbjct: 1 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLQDVIATDKEEIAFKDLDVAVLVGSMPRREGMERKD----LLKANVKIFKSQGTALEKYAKKSVKVIVVGNPA----NTNCLTASKSAPSIPKENFSCLTRLDHNRAKSQIALKLGVTADDVKNVIIWGNHSSTQYPDVNHAKVK-----LQGKE---VGVYEALKDDSWLKGEFITTVQQRGAAVIKARK-LSSAMSAAKAIADHIRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNK-TWKFVEGLPINDFSREKMDLTAKELTEEKETAFEFLSSA 334
BLAST of Malate dehydrogenase 1B vs. Ensembl Mouse
Match: Mdh1 (malate dehydrogenase 1, NAD (soluble) [Source:MGI Symbol;Acc:MGI:97051]) HSP 1 Score: 56.6102 bits (135), Expect = 5.867e-9 Identity = 43/159 (27.04%), Postives = 72/159 (45.28%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDD--RNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFN 889 +S P +V++ GA + + S+ G V + + +V +D T + +L + M D A L++ + TD E AF D + V+ R D +KAN + ++ G +EKY VKV++V A N N ++ + IPK N Sbjct: 1 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLQDVIATDKEEIAFKDLDVAVLVGSMPRREGMERKD----LLKANVKIFKSQGTALEKYAKKSVKVIVVGNPA----NTNCLTASKSAPSIPKEN 151
BLAST of Malate dehydrogenase 1B vs. UniProt/SwissProt
Match: sp|Q8T773|MDH1B_BRAFL (Putative malate dehydrogenase 1B OS=Branchiostoma floridae OX=7739 GN=MDH1B PE=3 SV=1) HSP 1 Score: 341.658 bits (875), Expect = 7.725e-109 Identity = 182/485 (37.53%), Postives = 288/485 (59.38%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSE---IQFKSINECIQDIIEKTRIIYPWINNSNQSEMV 1483 MAK V+AG +DCPY+AKVELLAD+L+ + +FHVHKIVKT +EW W +LC N W+ SPIIWRELVDRGGKG LIGG N+F EY + YY + S S M++IA +N+ + +E + S P V ++ A H + SL G +L E+A+ D E+L LK L+M FDL++ ++ IS+T + AF ++ + ++ DD + ++ I M+ +Y+ + I + S D++VL+ ++ L ++++ H IP+ N+ +++ E+Q +S++A++L VN + V + IVWGN+GG Y D + +RVH YDGA+ GP +S SV++ V D KWL+ E + +R I D + L++A+AI++ L W NG G + SL + SEG+Y +P+G+ FS PV + +G W VVQD++++E + SI Q + EK +++P N+N +++ Sbjct: 1 MAKFVIAGQADCPYYAKVELLADSLQSKLQDFHVHKIVKTPEEWKPWLQQLCADNGWTHGRSPIIWRELVDRGGKGLLIGGHNDFMEYARSYYGMTSGMLSEMMKNIAAENLAVTQELREEEETIRRQSKPLHVCVINAARSPAYHVLPSLVNGKILREE-EIALHLHDSEENLEKLKGLEMEVFDLSFPFLKEISVTTDLPTAFQNAHIAIVLDDFD--QGGKEDAIGDMETKVSFYKRVAEAINQTASKDIRVLVAGTGPLNSL-VSILIDHT--PSIPRQNIAAVAQVKERQAKSLLAKRLTVNSAGVCDVIVWGNVGGTTYTDVSRARVHGYDGAIWGPPSYSCSVSEMVHDNKWLEGEFLEQLQSRSHTIQD-SLQHSADLSMAAAISSTLSYWWNGSPEGQLFSLAVCSEGFYNIPEGVVFSFPVMFH-KGSWEVVQDIDMNEDMRVMLSSIT--AQLVEEKDLLLHP--TNANHEKLL 473
BLAST of Malate dehydrogenase 1B vs. UniProt/SwissProt
Match: sp|Q5I0G3|MDH1B_HUMAN (Putative malate dehydrogenase 1B OS=Homo sapiens OX=9606 GN=MDH1B PE=2 SV=1) HSP 1 Score: 266.929 bits (681), Expect = 2.343e-80 Identity = 167/465 (35.91%), Postives = 260/465 (55.91%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 MAK V+AG +DCPY+AK EL+AD L+ N+P+F +HKI + + W W ++C+ N WS K+SPIIWREL+DRGGKG L+GG NEF E+ + YY+V S T+ M IA +N+ +++E K P +V I A A + + L+ G+V +TE++I D + LKSL + T DLA ++RS+SI E AF + ++V+ DD E +++ G IEK V+V+ + +++N+ + + R RI N++ ++ VE + ++++ARKL PS + + I+WGNI G Y+D +RV+RY+ A+ GP +S V ++D +W+K E ++ N ++ G LA A +I T L W +G G I SL I SEG +G+P G+ FSMPV G W V+ D++ EI + + D+I++ Sbjct: 1 MAKFVIAGRADCPYYAKTELVADYLQKNLPDFRIHKITQRPEVWEDWLKDVCEKNKWSHKNSPIIWRELLDRGGKGLLLGGYNEFLEHAQLYYDVTSSMTTELMMVIAQENLGAHIEKEQEEEALKTCINPLQVWITSASAPACYNLIPILTSGEVFGMHTEISITLFDNKQAEEHLKSLVVETQDLASPVLRSVSICTKVEEAFRQAHVIVVLDDSTNKEVFTLE--DCLRSRVPLCRLYGYLIEKNAHESVRVI---VGGRTFVNLKTVLLMRYAPRIAH-NIIAVALGVEGEAKAILARKLKTAPSYIKDVIIWGNISGNNYVDLRKTRVYRYESAIWGPLHYSRPVLNLIFDSEWVKREFVAILKN----LTTTGRQFGGILA-AHSIATTLKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPVKFE-NGTWVVLTDLKDVEISEQIMTRMTSDLIQE 453
BLAST of Malate dehydrogenase 1B vs. UniProt/SwissProt
Match: sp|Q08BZ4|MDH1B_DANRE (Putative malate dehydrogenase 1B OS=Danio rerio OX=7955 GN=mdh1b PE=2 SV=1) HSP 1 Score: 255.758 bits (652), Expect = 7.736e-77 Identity = 153/463 (33.05%), Postives = 243/463 (52.48%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKE-NEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDI 1423 MAK V+AG +DCPY+AK ELLAD L+ N+P+FH+HKI +W W + C +N W SP++WREL+DRGGKG L+GG ++F E+ + YY + SD S M IA +N KE ++E+ K+L P + I A+N + L + + L++ +D + +L++L+M T DLA + + N D++N D D+ E++ G IE DV+VL + ++N+ + I N V ++ +E + R+ +A+KL+V S++ N IVWGNI G +ID ++V RYDGA+ GP+ FS V + ++D KWLK + L+ IS N T ++ +AI L W N + + SL + S G +G+P G+ FSMPV+ G+W+V DV +++ +++ C ++ Sbjct: 1 MAKFVLAGKADCPYYAKAELLADVLQRNLPDFHIHKIPVPPDDWKEWLEDTCASNGWKHSSSPLVWRELIDRGGKGMLLGGFSDFLEHAQGYYGITSDMKSDLMLKIAEENQATKELCMEEEVHRLKSLR-PLHIWISSALNPVCYSLIPHLFTPGLFSGLPILSLHLMDTSGSEEMLQALKMETVDLAIPRLHEPAGEYN--------------DEQN----DKDQV-------AEHFHRYGQLIETNAQKDVRVL---VAGDFFINMKCSLLIENAPSIDSRNFVAMTTQLEYEARTQLAQKLSVKTSDITNVIVWGNISGSFHIDLQRAKVFRYDGAIRGPDGFSQHVMEMIYDWKWLKTDFRSLLHKHRATISSKTNK-ATAISTTNAILAILKAWNNAESPEEVFSLGVLSTGQFGIPAGLVFSMPVSFT-DGHWSVRSDVTVTDELRVNLDACADEL 432
BLAST of Malate dehydrogenase 1B vs. UniProt/SwissProt
Match: sp|A3KMX7|MDH1B_BOVIN (Putative malate dehydrogenase 1B OS=Bos taurus OX=9913 GN=MDH1B PE=2 SV=1) HSP 1 Score: 251.521 bits (641), Expect = 5.663e-75 Identity = 165/487 (33.88%), Postives = 261/487 (53.59%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKF--NVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRIIYPWINNSN--QSEMVI 1486 MAK V+AG +DCPY+AK ELLAD L+ N+P+F +HKI + W W +LCK N WS SPIIWREL+DRGGKG L+GG NEF E+ + YY V S T+ M+ +A +N+ ++ E K L P +V I A + A H + L+ G+V E++I D L S + DLA ++S+SI E AF + +++I DD + E +++ + G+ IEK K++ + +++N+ +++ P F N++ ++ VE Q ++ +ARKL + PS + + I+WGNI G Y+D ++V+RY+ A+ GP +S V ++D++W+ E + + ++ G LA A +I T L W +G G I SL + SEG +G+P G+ FSMPV G W V+ D++ +EI + + D+I++ + + N QSE +I Sbjct: 1 MAKFVLAGRADCPYYAKAELLADYLQKNLPDFRIHKITQHPDIWEEWLKDLCKKNRWSHNKSPIIWRELLDRGGKGLLLGGYNEFLEHAQLYYGVTSSMTTELMKRVAQENLGTHIEKELEKESLKGLVNPLQVWITSASSLACYHLIPILTSGEVFGPQMEISINLFDNKHTEEKLISHKQEAEDLASPCLQSVSICTQAEEAFHGAHVIIILDDHVDKEINSLE--DCIRSRAPLCQLYGSLIEKNAHNFAKII---VGGKTFVNLK---TALLMKYAPTFAHNIIAVALGVEGQAKAALARKLKITPSCIKDVIIWGNISGNNYVDLRKAKVYRYESAIWGPPHYSRPVLSLLFDREWVNREF----VVSLKTLTATGRQFGGMLA-AHSIATTLKYWCHGSPPGEIVSLGVLSEGQFGIPKGIVFSMPVKFE-NGTWVVLTDLKNTEISQQVMTRMANDLIQEQLVALGELANFQPYQSENLI 473
BLAST of Malate dehydrogenase 1B vs. UniProt/SwissProt
Match: sp|Q5F204|MDH1B_MOUSE (Putative malate dehydrogenase 1B OS=Mus musculus OX=10090 GN=Mdh1b PE=2 SV=1) HSP 1 Score: 246.128 bits (627), Expect = 1.209e-72 Identity = 153/465 (32.90%), Postives = 252/465 (54.19%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 MAK V+AG ++CPY+AK ELLAD L+ N+P+F + KI + +W W ++C+ N W + SPIIWREL+DRGG+G L+GG NEF E+ + YY V S+ T+ M IA +N++ + + K L +P +V I A H + L G+V +TE+++ D+ + L+S+ M T DLA ++R++S + AF + +++I DD E +++ G IEK VKV+ + +++N+ + + I N++ ++ VE Q ++V+ARK+ +N+ + I+WGNI G Y+D ++V+ Y+ AV GP SV ++D++W+ E + + +S G LA A +I T L W +G G I SL + SEG + +P+G+ FSMPV G W V+ D+E + K+++ D+I++ Sbjct: 1 MAKFVIAGKANCPYYAKAELLADYLQKNLPDFRIFKITQHPDKWEDWVEDVCERNMWDHRTSPIIWRELLDRGGRGLLLGGYNEFLEHAQLYYGVTSNMTTELMMVIAKENMQTHTEQQLDKETMKDLISPLQVWIASAGTYVCCHLIPLLLSGEVFGMHTEISLTLFDQEQREDCLRSIVMETQDLASPVLRTVSFCTTVKEAFLQAQVIIILDDSTEEEVYSLESC--LRSRVPLCRLYGYLIEKNAHKSVKVI---VGGKNFVNLKTTLLMQYAPNIAS-NIIAVALGVEGQAKAVLARKMKTTSANIKDVIIWGNITGNNYVDLRKAKVYNYESAVKGPPGHYHSVLSLIFDREWITKEF----VQTLKILSSTGKQFGGILA-AHSIATTLKYWYHGSPPGEIVSLGVMSEGQFDIPEGIVFSMPVKFE-NGTWVVLTDLEDISLSEKTLSRLTGDLIQE 453
BLAST of Malate dehydrogenase 1B vs. TrEMBL
Match: K1QKI3 (Putative malate dehydrogenase 1B OS=Crassostrea gigas OX=29159 GN=CGI_10018565 PE=4 SV=1) HSP 1 Score: 372.474 bits (955), Expect = 4.580e-118 Identity = 196/465 (42.15%), Postives = 276/465 (59.35%), Query Frame = 2 Query: 59 GCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDR-NPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDV-ELSEIQFKSINECIQDIIEKTRIIY 1447 G SDCPY+A+ ELL D L N+P+F +HKIV +EW W E C + WS P++WREL+DRGGKG LIGGANEFQEY YY V S S M+ +A +N +K EDKE KALS P V I A N+ + + +++RGD+ TE+++ +D ++ L+ L+M DLA+ L+R I +T + AF +++ DD D+++ K + E++ I + +VKVLL N+N+ + + IPK N+VGLSRT+E +SVV KLNVNPS V + IVWGNI G YID + RVH YDGA+ GP FSL + +WDKKW++NE L+ R Q+ +L + ++ A+AI T + W NG G I SLV+ASEGWY VP+ + S PVT++P+G W VVQD+ + SE++ K I E ++DII +I+ Sbjct: 10 GKSDCPYYARSELLGDKLVKNLPDFQLHKIVIKPEEWDKWLKETCSSREWSHNKCPLVWRELIDRGGKGVLIGGANEFQEYAFGYYGVQSTQVSDDMRKMAEENKAYKIEEDKEEEAIKALSHPLNVCITNASNQVCYNLINAMARGDIFGETTEISLHLLDDKANMESLEGLRMEAMDLAHGLLREIIVTSDVSKAFQGCDAIIVMDDLVQKEKESRDDFV---KRSVEHHVKYAKVINEKAKKEVKVLLT---GTGPTNLNIYMMIQNAPNIPKQNIVGLSRTLENNAKSVVGEKLNVNPSGVVDLIVWGNINGGTYIDLSKCRVHGYDGAIWGPPSFSLPAVEMIWDKKWMENEFTELVKGRHQKSEELMKHSAS-MSTAAAIETTMAHWWNGTPEGQIFSLVVASEGWYEVPEELVCSFPVTISPKGNWCVVQDINQTSEVKEK-IKEAVKDIIADKNVIF 466
BLAST of Malate dehydrogenase 1B vs. TrEMBL
Match: A0A1S3J549 (putative malate dehydrogenase 1B OS=Lingula unguis OX=7574 GN=LOC106170262 PE=4 SV=1) HSP 1 Score: 368.622 bits (945), Expect = 2.134e-116 Identity = 184/469 (39.23%), Postives = 279/469 (59.49%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRII 1444 MAKIV+AG ++CPYFA+ ELLAD L N+ +F +HKIV +W W CK + SP++WRELVDRGGKG LIGGAN+FQEY YY + SDF S M+ I +N++ K DKE EF++ S P KV I A + H + S+ +GDV TE+++ +D E++ L+ +QM DLA+ L+R +S+ N AF D S ++ DD S D + W K N + + G+ +++ + +VL + +N N +H+ + +IP+ N+V LSR VE +++++ +L VN ++V + IVWGN+GG Y D + +R H YDGA+ GP FS S + V D KWL+ E + R + + + L+ A+A+ + L W NG G + S+ +ASEGWYGVP+G+ FS P T++P+GYW+V+QD+ELS+ I ++++I + +I Sbjct: 1 MAKIVLAGAANCPYFARCELLADTLADNLEDFKLHKIVVQPDKWQNWLESTCKERGFMHSSSPLVWRELVDRGGKGVLIGGANDFQEYAYGYYGIKSDFVSDDMKKIGEENLKVKIEVDKEEEEFRSRSRPLKVCITNASCDVCYHMISSIGQGDVFGKGTEISLHLLDTAENMEYLEGVQMEAIDLAHGLLRKVSVMTNPREAFMDCSAIIFLDDIVKS--DEESKDDWYKRNADCFTNYGHVLDEVAKKNARVL---VAGEGPVNFNTFILHQHITQIPRQNIVALSRMVENHAKAIISERLKVNSADVVDIIVWGNVGGTSYADMSLARTHNYDGAIWGPPFFSRSAVELVHDNKWLEKEFPEELAARGEMVGKALRKKPS-LSKAAAVVSQLAHWWNGSPSGQMWSMGVASEGWYGVPEGLVFSFPTTMSPKGYWSVIQDIELSDETKDKIQTIVKELISEKEVI 463
BLAST of Malate dehydrogenase 1B vs. TrEMBL
Match: A0A1S3H2A8 (putative malate dehydrogenase 1B OS=Lingula unguis OX=7574 GN=LOC106151071 PE=4 SV=1) HSP 1 Score: 368.237 bits (944), Expect = 3.766e-116 Identity = 184/469 (39.23%), Postives = 280/469 (59.70%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRII 1444 MAKIV+AG ++CPYFA+ ELLAD L N+ +F +HKIV +W W CK + SP++WRELVDRGGKG LIGGAN+FQEY YY + SDF S M+ I +N++ K DKE EF++ S P KV I A + H + S+ +GDV TE+++ +D E++ L+ +QM DLA+ L+R +S+ N + AF D S ++ DD S D + W K N + + G+ +++ + +VL + +N N +H+ + +IP+ N+V LSR VE +++++ +L VN ++V + IVWGN+GG Y D + +R H YDGA+ GP FS S + V D KWL+ E + R + + + L+ A+A+ + L W NG G + S+ +ASEGWYGVP+G+ FS P T++P+GYW+V+QD+ELS+ I ++++I + +I Sbjct: 1 MAKIVLAGAANCPYFARCELLADTLADNLEDFKLHKIVVQPDKWQNWLESTCKERGFIHGSSPLVWRELVDRGGKGVLIGGANDFQEYAYGYYGIKSDFVSDDMKKIGEENLKVKIEVDKEEEEFRSRSRPLKVCITNASCDVCYHMISSIGQGDVFGKGTEISLHLLDTAENMEYLEGVQMEAIDLAHGLLRKVSVMTNPKEAFMDCSAIIFLDDIVKS--DEESKDDWYKRNADCFTNYGHVLDEVAKKNARVL---VAGEGPVNFNTFILHQHITQIPRQNIVALSRMVENHAKAIISERLKVNSADVVDIIVWGNVGGTSYADMSLARTHNYDGAIWGPPFFSRSAVELVHDNKWLEKEFPEELAARGEMVGKALRKKPS-LSKAAAVVSQLAHWWNGSPSGQMWSMGVASEGWYGVPEGLVFSFPTTMSPKGYWSVIQDIELSDETKDKIQTIVKELISEKEVI 463
BLAST of Malate dehydrogenase 1B vs. TrEMBL
Match: A0A2C9JX51 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106071519 PE=4 SV=1) HSP 1 Score: 361.303 bits (926), Expect = 1.676e-113 Identity = 195/472 (41.31%), Postives = 273/472 (57.84%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAI-VFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDD--RNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRII 1444 MAKIV+AG SDCPYFA+VELL D L N+ F +HK++ +W W C W SPIIWREL+DRGGKG LIGGANEFQEY+K YY+V S+ TS M+ +A +N + K+ D+E + FK+LS P V I A + H + S+S G VL EL I + V+ E L + M DLA L+R + + E AF D +++ D+ R YI +M + + G I+K + KVL+ I N N + R Q+I + NVV ++ VE Q +SV+ KLNVNP+ V N +VWGNI K ++D + +VH YDGA+ GP +S++ + + D KWL +E L+ R ++S + G + L+ A++I+T L W G HG I SL + SEGWYGVP+G+ FS PVT++P+GYW VVQDV L+ +I I+D+ + II Sbjct: 1 MAKIVIAGRSDCPYFARVELLGDRLAKNLKKFKLHKLMIQPDKWDEWLHTTCAERGWEFHSSPIIWRELIDRGGKGVLIGGANEFQEYVKAYYDVESEMTSYEMRMVAAENKKTKDELDEEEKYFKSLSNPVNVCITNAASPVCYHLLHSISTGQVLGPKVELVIHLLVNSEEDLEQVMGTAMEAEDLALSLLRDVKVFTEAEEAFKDCQIIIFLDEIQRQEDMTMRKWYIQYMA----LFTFYGEIIDKKALRNCKVLVCGNGPI---NFNATILARSAQKIARQNVVAVASVVENQAKSVIGEKLNVNPAGVVNLLVWGNINAKRHLDVSKCQVHGYDGAITGPSWYSVNAIEMLHDNKWLSSEFPALVSARHLKVSRV-MGRSSSLSTANSISTLLKLWFRGSPHGQIFSLAVYSEGWYGVPEGIFFSFPVTMDPKGYWHVVQDVFLTLETKLNIKSSIEDLQYELGII 464
BLAST of Malate dehydrogenase 1B vs. TrEMBL
Match: A0A210Q1L4 (Malate dehydrogenase 1B OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT04875 PE=4 SV=1) HSP 1 Score: 359.762 bits (922), Expect = 1.056e-112 Identity = 195/472 (41.31%), Postives = 282/472 (59.75%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDD--RNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRIIY 1447 MAK+V+AG +DCPY+A+ ELL D L N+P+F +HKIVK EW W C W+ SPI+WREL+DRGGKG LIGGAN+FQEY YY + S+ SS M I+ +N+++K+ D+E +EFKA S P V + A N A V ++S+GDV S E+A+ D + + +L+ L+M DLA+ L+R +++ N AF++ S +++ D+ RN D D W K N + I +VKVLL + N N+ + + IP+ N GLSR +E ++V+A KL VN S V N ++WGN+ G+ YID SRVH Y+GA+ GP FSL + +WDK+WL E L+ R + + N G ++ +AI T LG W G G I SL + SEGWYGVPDG+ +S PVT++P+GYW VV+D++L+E +++ +QD+I + I+Y Sbjct: 1 MAKVVIAGKADCPYYARCELLGDKLAKNLPDFCLHKIVKQNDEWEKWLKATCNERGWTHMKSPIVWRELIDRGGKGVLIGGANDFQEYAHGYYGMESELLSSDMLKISKENLQYKKEVDEEEKEFKAQSKPLHVCLTVASNPACYAMVNAISKGDVFGSKQEVALHLYDANDKMEMLEGLRMEAIDLAHGLLRDVTVESNLCKAFSNCSAIILMDEVVRNEGE-DKD---SWYKRNSNLFCNYAKIINDVARKNVKVLLTGDGPV---NFNVFMMLQNAPNIPRQNFAGLSRMLENHTKAVIADKLKVNSSGVVNVVIWGNVSGEYYIDLETSRVHGYEGAIWGPPSFSLPTKEMIWDKQWLAKEFPELVKARKAMVEEALNH-GAYMSKGAAIATMLGHWWTGSPSGEIFSLAVCSEGWYGVPDGLVYSFPVTMHPKGYWYVVEDIDLTEEVKETLKVTVQDLISEKEIMY 464
BLAST of Malate dehydrogenase 1B vs. Ensembl Cavefish
Match: mdh1b (malate dehydrogenase 1B [Source:NCBI gene;Acc:103037214]) HSP 1 Score: 248.054 bits (632), Expect = 1.384e-74 Identity = 147/467 (31.48%), Postives = 247/467 (52.89%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKE-IREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDD---RNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELS-EIQFK---SINECI 1414 MAK V+AG +DCP++AK ELLAD L+ +P+FH+HKI +W W C +N W + SPI+WREL+DRGGKG L+GG ++F E+++ YY + SD S M IA +N+R E +E R+ ++L + I GA++ + L +++ + +++ +D L L+M T DLA + +++ + AF + L++ DD + +P + + + E + G +E DV+V+ + SY+N+ + + V ++ +E + R+ +A KL+V +++ + IVWGNI G ++D ++V RY G++ GP FS V + ++DKKWL+ + L+ R + IS N A + I L W N + SL + S G +GVP G+ FS+PV + G W+V D+ ++ E++ K +INE + Sbjct: 1 MAKFVLAGRADCPHYAKTELLADLLQKILPDFHIHKICVHPSDWQDWLEGTCSSNGWKHESSPIVWRELIDRGGKGMLLGGFSDFLEHVQGYYGITSDMGSEQMMKIAAENLRVTEVLMEEAARQNQSLQV-FHIWITGALSPTCYSLIPKLFTTELIRDISTISLHLLDVNSSEESLLGLKMETEDLALSQLHEVTVHSDMTWAFQSADLILFLDDWPSNSETPVEQGDKDHMVSQVAERFRSYGRLVEANAQKDVRVM---VAGDSYVNLKCSLLIENAPSVDPCRFVAMTTQLEYEARAQLAEKLSVKTTDITDIIVWGNISGSSHVDLQRAKVFRYKGSIWGPTGFSQQVLEMIYDKKWLETDFLSLVALRRRAISLKTNRTAANSA-TNGILAVLNAWSNCYSSREVFSLGVVSSGNFGVPAGLVFSVPVKFH-NGDWSVCSDITINDELRSKLGVAINELL 461
BLAST of Malate dehydrogenase 1B vs. Ensembl Cavefish
Match: mdh1b (malate dehydrogenase 1B [Source:NCBI gene;Acc:103037214]) HSP 1 Score: 228.024 bits (580), Expect = 2.313e-67 Identity = 143/464 (30.82%), Postives = 234/464 (50.43%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKE-IREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELS-EIQFK---SINECI 1414 MAK V+AG +DCP++AK ELLAD L+ +P+FH+HKI +W W C +N W + SPI+WREL+DRGGKG L+GG ++F E+++ YY + SD S M IA +N+R E +E R+ ++L + I GA++ + L +++ + +++ +D L L+M T DLA + + D D + + E + G +E DV+V+ + SY+N+ + + V ++ +E + R+ +A KL+V +++ + IVWGNI G ++D ++V RY G++ GP FS V + ++DKKWL+ + L+ R + IS N A + I L W N + SL + S G +GVP G+ FS+PV + G W+V D+ ++ E++ K +INE + Sbjct: 1 MAKFVLAGRADCPHYAKTELLADLLQKILPDFHIHKICVHPSDWQDWLEGTCSSNGWKHESSPIVWRELIDRGGKGMLLGGFSDFLEHVQGYYGITSDMGSEQMMKIAAENLRVTEVLMEEAARQNQSLQV-FHIWITGALSPTCYSLIPKLFTTELIRDISTISLHLLDVNSSEESLLGLKMETEDLALSQLHETPV----------------------EQGDKDHMVSQVA---ERFRSYGRLVEANAQKDVRVM---VAGDSYVNLKCSLLIENAPSVDPCRFVAMTTQLEYEARAQLAEKLSVKTTDITDIIVWGNISGSSHVDLQRAKVFRYKGSIWGPTGFSQQVLEMIYDKKWLETDFLSLVALRRRAISLKTNRTAANSA-TNGILAVLNAWSNCYSSREVFSLGVVSSGNFGVPAGLVFSVPVKFH-NGDWSVCSDITINDELRSKLGVAINELL 433
BLAST of Malate dehydrogenase 1B vs. Ensembl Cavefish
Match: mdh1aa (malate dehydrogenase, cytoplasmic [Source:NCBI gene;Acc:103036835]) HSP 1 Score: 109.383 bits (272), Expect = 1.404e-25 Identity = 88/345 (25.51%), Postives = 153/345 (44.35%), Query Frame = 2 Query: 401 IREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQ-WINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 +R A + P +V++ GA + + S+++GDV + + +V +D LP+L + M D A L+R + TD E F D ++ + E +KAN ++ G +EKY VKVL+V A N N + + IPK N L+R + RS VA ++ V+ V N I+WGN Y D +++ V+++ G E + V D WLK + + R + L + ++ A AI + W + ++ V +S YGV D + +S PV + + W VV + +++ ++ ++IE+ Sbjct: 12 VRAASAQAEPIRVLVTGAAGQIAYSLLYSIAKGDVFGKDQPIILVLLDIPPMLPVLDGVVMELQDCALPLLREVIPTDKVEVGFKDLDAAILVGSMPRK--EGMERKDLLKANVAIFKTQGAALEKYAKKTVKVLVVGNPA----NTNCLIASKSAPSIPKENFSCLTRLDHNRARSQVAMRVGVSSDKVKNVIIWGNHSSTQYPDVHHATVNQH-----GKE---VPAYDAVKDDSWLKADFISTVQQRGAAVIKARK-LSSAMSAAKAICDHMRDIWFGTPDGEFVSMGVYSSGNSYGVADDLMYSFPVMIKNKS-WKVVDGLPINDFSRGKMDATAAELIEE 340
BLAST of Malate dehydrogenase 1B vs. Ensembl Cavefish
Match: mdh1ab (malate dehydrogenase, cytoplasmic [Source:NCBI gene;Acc:103033607]) HSP 1 Score: 108.227 bits (269), Expect = 2.614e-25 Identity = 86/339 (25.37%), Postives = 153/339 (45.13%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEG-WYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 ++ +V++ GA + + S+++GDV + L +V +D LP+L+ + M D A +++ + TD E AF D ++ + E +KAN ++ G ++KY VKVL+V A N N + + IPK N L+R + RS VA + + NV N I+WGN Y D ++ V +V G + + + K D WLK + + R + L + ++ A AI + NG G S+ + S G YGVP+ + +S PVT+ + W +V + +++ ++ +++E+ Sbjct: 1 MAETIRVLVTGAAGQIAYSLLYSIAKGDVFGRDQPLVLVLLDIPPMLPVLEGVVMELQDCALPILKEVIPTDKEEVAFKDLDAAILVGSMPRK--EGMERKDLLKANVAIFKSQGAALDKYAKKTVKVLVVGNPA----NTNCLVAAKSAPSIPKENFSCLTRLDHNRARSQVAMRCGIPADNVKNVIIWGNHSSTQYPDVHHCMV-----SVGGKDVAAFDMVK---DDDWLKGDFISTVQQRGAAVIKARK-LSSAMSAAKAICDHMRDIWNGTPEGEFISMGVYSTGNPYGVPEDLIYSFPVTIKDKS-WKIVDGLAINDFSRAKMDATAAELVEE 323
BLAST of Malate dehydrogenase 1B vs. Ensembl Cavefish
Match: mdh1aa (malate dehydrogenase, cytoplasmic [Source:NCBI gene;Acc:103036835]) HSP 1 Score: 107.842 bits (268), Expect = 3.247e-25 Identity = 86/339 (25.37%), Postives = 151/339 (44.54%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQ-WINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 ++ P +V++ GA + + S+++GDV + + +V +D LP+L + M D A L+R + TD E F D ++ + E +KAN ++ G +EKY VKVL+V A N N + + IPK N L+R + RS VA ++ V+ V N I+WGN Y D +++ V+++ G E + V D WLK + + R + L + ++ A AI + W + ++ V +S YGV D + +S PV + + W VV + +++ ++ ++IE+ Sbjct: 1 MAEPIRVLVTGAAGQIAYSLLYSIAKGDVFGKDQPIILVLLDIPPMLPVLDGVVMELQDCALPLLREVIPTDKVEVGFKDLDAAILVGSMPRK--EGMERKDLLKANVAIFKTQGAALEKYAKKTVKVLVVGNPA----NTNCLIASKSAPSIPKENFSCLTRLDHNRARSQVAMRVGVSSDKVKNVIIWGNHSSTQYPDVHHATVNQH-----GKE---VPAYDAVKDDSWLKADFISTVQQRGAAVIKARK-LSSAMSAAKAICDHMRDIWFGTPDGEFVSMGVYSSGNSYGVADDLMYSFPVMIKNKS-WKVVDGLPINDFSRGKMDATAAELIEE 323
BLAST of Malate dehydrogenase 1B vs. Ensembl Sea Lamprey
Match: mdh1b (malate dehydrogenase 1B, NAD (soluble) [Source:NCBI gene;Acc:767794]) HSP 1 Score: 254.988 bits (650), Expect = 5.208e-78 Identity = 153/458 (33.41%), Postives = 246/458 (53.71%), Query Frame = 2 Query: 56 AGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIE 1429 +G +DCPY+AK ELL D L++N+P+F VHKI +EW AW S C+ + W SP++WRELV+RGG+G L+GG N+F EY++ YY ++S S M +A +N+ + E + + LS P V I GA + VP + L G++ +T L++ + K L+ ++ T D+A +R ++I + E AF + LV++ D N +P E W A G+ + + DV+VL+ K + L L++ +P+ N V LS +E++ + ++A KL VN + V + +VWG+ GG Y + +R+ YDGAV GP + + + + D++WL+NE P L + G AL +AI + L W +G + IHSL + S G YG+ G+ FS+PV G W+VV D+ L++ + I+ ++ E Sbjct: 8 SGRADCPYYAKAELLTDYLQLNLPSFRVHKIPVLPEEWEAWLSATCRQHGWRHTTSPLVWRELVERGGRGALLGGYNDFMEYVQGYYGMVSPMLSELMLTLAQENLHTQVKLTDEQAQHRELSRPFHVCITGANSACVPGLLWLLGTGELCGGSTGLSVCLLGKVGEQEALRCVRQDTLDMACAALRDVTIHSDPELAFDGAGLVIVLD--NVAPGLGQE---WSDAGAPLCAAYGSALGRRAGPDVRVLVAAAKGAN-LRAQLLATAAA-PHVPRRNFVALSTHLERRAKGLLAAKLKVNSAGVEDVVVWGDAGGSTYTQLSAARLRGYDGAVWGPG-LTYPLLEVLNDREWLENEF-PAALQARGSLQAKAQGYPATTALNAAIASTLRLWFHGSDDQQIHSLAVPSNGEYGLLQGLVFSLPVRFE-GGDWSVVSDLSLTDAERSRIHAIAAELQE 455
BLAST of Malate dehydrogenase 1B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007050.1 (pep scaffold:Pmarinus_7.0:GL479360:144570:153551:-1 gene:ENSPMAG00000006369.1 transcript:ENSPMAT00000007050.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 52.373 bits (124), Expect = 2.781e-8 Identity = 44/165 (26.67%), Postives = 77/165 (46.67%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFAD--SSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSR 907 ++ KV++ GA + + S++ G+V + +++V +D T L +L+ + M D A L++ + TD E AF D ++++V R D +KAN ++ G + KY VKVL+V A N N + + IP+ N L+R Sbjct: 1 MTGTVKVLVTGAAGQIAYSLLYSIASGNVFGKDQPISLVLLDITPMLGVLEGVVMELQDCALPLLKEVIATDKEEVAFKDLDAAILVGSMPRREGMERKD----LLKANVRIFKSQGAALNKYSKKTVKVLVVGNPA----NTNCLIALKSALTIPRENFTCLTR 157
BLAST of Malate dehydrogenase 1B vs. Ensembl Nematostella
Match: EDO45840 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRY2]) HSP 1 Score: 272.322 bits (695), Expect = 2.453e-84 Identity = 165/470 (35.11%), Postives = 253/470 (53.83%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPA-DPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPE--PFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTR 1438 MAK VV+G SDCP++AK ELLAD L +N+P+F VHKIVK EW W +++C N W SP+IWRELVDRGGKG L+GG ++F E+ + YY + S S+ + I+ +N K DKE E P +V + A + SL +G+V E++I +D E+ L+ + D A+ L R + IT + AF D+S+VV+ D + + D EY + ++ + + G +E + D KVL A N + + I K N V LSR E + + ++A++LNVN + + + IVWGN G Y D +++RV +DGA+ GP F+ V + V D KWL E + ++ S+ N L +A+ S + + Q + D + SL + SEGWY +P+G+AFS PV G W VV+ + LS+ S+ E +++I ++ + Sbjct: 1 MAKFVVSGRSDCPFYAKAELLADELSLNLPDFKVHKIVKRPDEWDDWMNKMCDDNGWKHSGSPLIWRELVDRGGKGILLGGCDDFLEFAEGYYGLASRLKSAKLVSISEENKSTKIEVDKEEEELAKKINPLRVCVSKASGPLAYGMLASLVQGEVFGFQEEVSIYLLDTPENQEALQGVAYEIEDCAWPLFRGVHITSDPAVAFKDASVVVLLDGKAINEGTDKKEY---LLSHAKLFRDYGKALEAHAKPDCKVLTAGGPA----NFSTFIASKFAPSIQKKNFVSLSRIEENRAKGLIAKRLNVNTAGIKDLIVWGNPGFNHYPDASHARVDGFDGAIWGPHVPGFTRPVPEMVHDNKWLSGEF----VEVLKKPSEGENALMGSVAVKSLLQDWC-QCASSD----MWSLGVISEGWYDIPEGIAFSFPVKFT-GGSWQVVEGLALSD----SLKEVLKNIAQEAK 449
BLAST of Malate dehydrogenase 1B vs. Ensembl Nematostella
Match: EDO41218 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4V3]) HSP 1 Score: 106.686 bits (265), Expect = 3.071e-25 Identity = 84/330 (25.45%), Postives = 148/330 (44.85%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSP-ADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSIN 1405 ++ P +V I GA + + S+++GDV +N + + +D T + L + + D A L+ + TD+ E AF D + ++ P + E + AN + +E G ++K K+L+V A N N + R IPK N L+R + + S +A +LN+ V N I+WGN Y D N+ +V V G +++ V D +L E + R I L + ++ A AI + W G G S+ + S+G YG+ +G+ +S PV + + W +VQ + +++ + +N Sbjct: 1 MAEPLRVCITGAAGQIAYSLLYSVAKGDVFGANQPIILHLLDITPMMGALGGVVLELQDCAIPLLHEVVATDDAEKAFTDIDVAILV---GAMPRREGMERKDLLSANAKIFEAQGKALDKVAKKTCKILVVGNPA----NTNCLIAQRWAPSIPKENFSCLTRLDQNRGGSQIAGRLNLRVDQVKNVIIWGNHSATQYPDVNHGKV-----CVNGNW---VAIRDAVKDDDYLNGEFISTVQKRGAAIIKARK-LSSAMSAAKAICDHMRDWWFGTREGEWVSMGVVSDGSYGIEEGLVYSFPVQICDR-TWKIVQGLSINDFSREKMN 313
BLAST of Malate dehydrogenase 1B vs. Ensembl Medaka
Match: mdh1b (malate dehydrogenase 1B [Source:NCBI gene;Acc:101155092]) HSP 1 Score: 201.06 bits (510), Expect = 4.712e-57 Identity = 137/466 (29.40%), Postives = 230/466 (49.36%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQE----YYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDI 1423 MAK VVAG +DCP++A+ E LAD L+ ++PNF HKI EW W C N W ++SP++WRELV++GGKG L+GG ++F + + YY V SD M +A +N+ + +E ++ L P V I GA + + +L ++ +++ +D E+ L+ L+ T LA ++R +++ + + AF ++ ++V+ DD N E K + Y I+ + VKV+ + S++N+ + I V ++ +E + R+VVA KL V P+ V IVWGNI G YID ++V + G + GP F +++ + D+KWL+ ++ L+ R ++ G + AS I L W G I S + G + + D + FS+PVT G W++V DV + + + + C ++ Sbjct: 1 MAKFVVAGKADCPFYAEAERLADTLQRSLPNFRAHKICVLPDEWEGWLDGTCSKNGWKHEESPLVWRELVEQGGKGLLLGGLSDFLNHCQDYYGVSSDVNPDMMLSVAAENLETQIKLLQEEQDHLNLVKPIHVWITGAASHTSRILIPNLLSAEIFPKAPAVSLHLLDLDENEEELQRLREETQSLALSMLRRVTVHTDPQQAFREADVIVLLDDTNGGRRGEGEEEEEEKQEVKSVCNRYREFSRLIDAKANKQVKVI---VSGDSHVNLRCSLLVEGAHSIDSHQFVAVATQLENEARAVVAEKLGVRPTEVTEVIVWGNISGLSYIDLQRAKVFNFQGPIKGPAFFPQPISRILPDRKWLETNLQDLVRRRRDAVTS-RTGQAASASAASGILRVLKAWHAGGGPDEIMSAGVHCSGLFNLRDDIIFSVPVTFEG-GKWSMVLDVTVGDGLMRRLELCADEL 461
BLAST of Malate dehydrogenase 1B vs. Ensembl Medaka
Match: mdhb (cytosolic malate dehydrogenase B [Source:NCBI gene;Acc:100049475]) HSP 1 Score: 108.227 bits (269), Expect = 2.698e-25 Identity = 84/339 (24.78%), Postives = 149/339 (43.95%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEG-WYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 ++ P V++ GA + + S+++GDV + + ++ +D T LP+L+ + M D A L+R + TD E AF D ++ + E +KAN + G ++KY V VL+V A N N + + IPK N L+R + S VA + V ++V N I+WGN Y D ++ +V G L+ V D WLK + + R + L + ++ A AI + +G G S+ + S G YGVP+ + +S PV + + W +V + +++ ++ +++E+ Sbjct: 1 MAEPISVLVTGAAGQIAYSLLFSIAKGDVFGKDQPIILLLLDITPMLPVLEGVVMELQDCALPLLREVIATDKEEVAFKDLDAAILVGSMPRK--EGMERKDLLKANVAIFRSQGAALDKYAKKTVHVLVVGNPA----NTNCLIAAKSAPSIPKENFSCLTRLDHNRACSQVAMRCGVPATHVKNVIIWGNHSSTQYPDVHHCKVSMSSG--------ELACFDAVKDDSWLKGDFIATVQQRGAAVIKARK-LSSAMSAAKAICDHMRDIWSGTPEGEFISMGVYSTGNPYGVPEDLIYSFPVQIKDKA-WKIVDSLAINDFSKSKMDATAAELMEE 323
BLAST of Malate dehydrogenase 1B vs. Ensembl Medaka
Match: mdh1 (malate dehydrogenase 1 [Source:NCBI gene;Acc:100302445]) HSP 1 Score: 105.916 bits (263), Expect = 1.556e-24 Identity = 83/339 (24.48%), Postives = 152/339 (44.84%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQ-WINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 ++ P +VV+ GA + + S+++GDV + + ++ +D LP+L + M D A L+R + TD E F D ++ + + E +KAN ++ G ++KY VKVL+V A N N + + IPK N L+R + S VA + V+ V N I+WGN Y D ++++V+ V G E +S V + WL+ + + R + L + ++ A AI + W E +I V A+ YG+P+ + +S P+ + + W VV + +++ ++ +++E+ Sbjct: 1 MAEPIRVVVTGAAGQIAYSLLFSIAKGDVFGKDQPIILILLDIPPMLPVLDGVVMELQDCALPLLREVIPTDKVEVGFKDIDAAILVG--SMPRKEGMERKDLLKANVAIFKTQGQALDKYAKKTVKVLVVGNPA----NTNCLIASKSAPSIPKENFSCLTRLDHNRACSQVAMRCGVSSDKVKNVIIWGNHSSTQYPDVHHAKVN-----VSGSE---VSAYDAVKNDAWLRGDFISTVQLRGAAVIKARK-LSSAMSAAKAICDHMRDIWFGTKEGEFISMGVYAAGNSYGIPEDLIYSFPIQIKNK-TWKVVDGLPINDFSRAKMDATAAELVEE 323
BLAST of Malate dehydrogenase 1B vs. Ensembl Medaka
Match: mdh1 (malate dehydrogenase 1 [Source:NCBI gene;Acc:100302445]) HSP 1 Score: 105.916 bits (263), Expect = 2.084e-24 Identity = 84/345 (24.35%), Postives = 152/345 (44.06%), Query Frame = 2 Query: 401 IREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQ-WINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 +R + P +VV+ GA + + S+++GDV + + ++ +D LP+L + M D A L+R + TD E F D ++ + E +KAN ++ G ++KY VKVL+V A N N + + IPK N L+R + S VA + V+ V N I+WGN Y D ++++V+ V G E +S V + WL+ + + R + L + ++ A AI + W E +I V A+ YG+P+ + +S P+ + + W VV + +++ ++ +++E+ Sbjct: 12 VRAISPQAEPIRVVVTGAAGQIAYSLLFSIAKGDVFGKDQPIILILLDIPPMLPVLDGVVMELQDCALPLLREVIPTDKVEVGFKDIDAAILVGSMPRK--EGMERKDLLKANVAIFKTQGQALDKYAKKTVKVLVVGNPA----NTNCLIASKSAPSIPKENFSCLTRLDHNRACSQVAMRCGVSSDKVKNVIIWGNHSSTQYPDVHHAKVN-----VSGSE---VSAYDAVKNDAWLRGDFISTVQLRGAAVIKARK-LSSAMSAAKAICDHMRDIWFGTKEGEFISMGVYAAGNSYGIPEDLIYSFPIQIKNK-TWKVVDGLPINDFSRAKMDATAAELVEE 340
BLAST of Malate dehydrogenase 1B vs. Ensembl Medaka
Match: mdh1 (malate dehydrogenase 1 [Source:NCBI gene;Acc:100302445]) HSP 1 Score: 105.145 bits (261), Expect = 2.673e-24 Identity = 83/338 (24.56%), Postives = 150/338 (44.38%), Query Frame = 2 Query: 422 STPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQ-WINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 + P +VV+ GA + + S+++GDV + + ++ +D LP+L + M D A L+R + TD E F D ++ + E +KAN ++ G ++KY VKVL+V A N N + + IPK N L+R + S VA + V+ V N I+WGN Y D ++++V+ V G E +S V + WL+ + + R + L + ++ A AI + W E +I V A+ YG+P+ + +S P+ + + W VV + +++ ++ +++E+ Sbjct: 4 AEPIRVVVTGAAGQIAYSLLFSIAKGDVFGKDQPIILILLDIPPMLPVLDGVVMELQDCALPLLREVIPTDKVEVGFKDIDAAILVGSM--PRKEGMERKDLLKANVAIFKTQGQALDKYAKKTVKVLVVGNPA----NTNCLIASKSAPSIPKENFSCLTRLDHNRACSQVAMRCGVSSDKVKNVIIWGNHSSTQYPDVHHAKVN-----VSGSE---VSAYDAVKNDAWLRGDFISTVQLRGAAVIKARK-LSSAMSAAKAICDHMRDIWFGTKEGEFISMGVYAAGNSYGIPEDLIYSFPIQIKNK-TWKVVDGLPINDFSRAKMDATAAELVEE 325
BLAST of Malate dehydrogenase 1B vs. Planmine SMEST
Match: SMESG000070444.1 (SMESG000070444.1) HSP 1 Score: 1165.6 bits (3014), Expect = 0.000e+0 Identity = 600/607 (98.85%), Postives = 600/607 (98.85%), Query Frame = 2 Query: 38 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEKTRIIYPWINNSNQSEMVIDESFIDSQINALLHEIYPKNEIPSILALITNXXXXXXXXXXXXXXXXXXXTTVSDLRKPPPVKERTDITNPESLPDAQNLSPTNNINAFXXXXXXXXXXXXXXXDPPEHLTTDPSTNDHEDQLE 1858 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDI EKTRIIYPWINNSNQSEMVIDESFIDSQINALLHEIYPKNEIPSILALITNSSLLLEDKLDISKSKDLLLTTVSDLRKPPPVKERTDITNPESLPDAQNLSPTNNINAF ITETSITESDPPEHLTTDPSTNDHEDQLE Sbjct: 1 MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSELCKTNNWSIKDSPIIWRELVDRGGKGHLIGGANEFQEYIKCYYNVISDFTSSHMQDIALDNVRFKENEDKEIREFKALSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDINEKTRIIYPWINNSNQSEMVIDESFIDSQINALLHEIYPKNEIPSILALITNSSLLLEDKLDISKSKDLLLTTVSDLRKPPPVKERTDITNPESLPDAQNLSPTNNINAF-----EITETSITESDPPEHLTTDPSTNDHEDQLE 602
BLAST of Malate dehydrogenase 1B vs. Planmine SMEST
Match: SMESG000056995.1 (SMESG000056995.1) HSP 1 Score: 119.398 bits (298), Expect = 2.567e-29 Identity = 89/339 (26.25%), Postives = 155/339 (45.72%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADSSLVVIFDDRNPSP-ADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSEIQFKSINECIQDIIEK 1432 ++ P VV+ GA + V S++ G+V + + + +D +P LK L M D A+ + S+ TD+ + AF D ++ P + E +KAN ++ G ++KY KV +V A N N + + + IPK N L+R + ++ +A K V +V ++WGN Y D N+ VH +DG +S+ V D WLKN+ + R + L + L+ A A+ W +G + S+ + S+G YGVP + FS PVT++ G W +VQ + + + + ++ +++IE+ Sbjct: 1 MTPPITVVLTGAAGQIGYCLVHSVASGNVFGPHQPINLHLLDIPVMVPSLKGLIMELEDCAFPTLHSVIATDDLKEAFTDVDFALMV---GAMPRKEGMERKDLLKANVNIFKVQGEALDKYAKKTAKVCVVGNPA----NTNCLVMSKYAPSIPKENFSALTRLDHNRAQAQIAAKAGVPCDHVKRCVIWGNHSNTQYPDVNHGLVHGHDGK-------EVSIKDAVKDDTWLKNDFIKTVQTRGAAVIAARK-LSSALSAAKAVADHCRDWFHGTKEWV--SMAVYSDGSYGVPKDVIFSFPVTID-HGKWHIVQGLTIDDFSRQKLDLTGKELIEE 321
BLAST of Malate dehydrogenase 1B vs. Planmine SMEST
Match: SMESG000027913.1 (SMESG000027913.1) HSP 1 Score: 108.227 bits (269), Expect = 1.675e-25 Identity = 87/324 (26.85%), Postives = 145/324 (44.75%), Query Frame = 2 Query: 419 LSTPTKVVIVGAVNEAVPHFVLSLSRGDVLNSNTELAIVFVDKTEHLPILKSLQMGTFDLAYRLVRSISITDNFEAAFADS--SLVVIFDDRNPSPADPDEYIPWMKANQEYYEYIGNFIEKYCSLDVKVLLVPIKAISYLNINLISIHRMLQRIPKFNVVGLSRTVEQQVRSVVARKLNVNPSNVHNNIVWGNIGGKMYIDTNNSRVHRYDGAVMGPEPFSLSVTKTVWDKKWLKNEMEPLILNRFQEISDLNNGLGTPLALASAITTFLGQWINGDEHGYIHSLVIASEGWYGVPDGMAFSMPVTLNPQGYWTVVQDVELSE 1384 +S P V+I GA + V +++ G V ++ + D + +P LK L M D ++ ++SI T + + F D +L+V R D E +KAN ++ G +++KY VKV++V A N N + + IPK N L+R + +S +A K+ V ++VH ++WGN G Y D N V +G +SV + V + WL+ E + R + L + ++ A AI W G S+ + S+G Y P + FS PVT+ G WT+V +++ + Sbjct: 1 MSAPIHVLITGAAGQIGYSLVGNIANGSVFGEKQQVILHLFDIPDMVPALKGLVMELEDCSFPTLKSIIATGDAKEGFTDIDWALMVGAMPRK----DGMERRDLLKANVSIFKVQGEYLDKYAKKTVKVIVVGNPA----NTNCFILSKYAPSIPKENFSALTRLDHNRAQSQIALKVGVGFTDVHRVVIWGNHSGTQYPDVTNGLVKLANGK-------EVSVKEAVKNDGWLQEEFLKTVQTRGAAVIAARK-LSSAMSAAKAICDHCRDWFKGTSDWV--SMAVYSDGSYNSPKDIIFSFPVTIK-NGKWTIVTGLKIDD 305 The following BLAST results are available for this feature:
BLAST of Malate dehydrogenase 1B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Malate dehydrogenase 1B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of Malate dehydrogenase 1B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 2
BLAST of Malate dehydrogenase 1B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Malate dehydrogenase 1B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Malate dehydrogenase 1B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Malate dehydrogenase 1B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Malate dehydrogenase 1B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Malate dehydrogenase 1B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Malate dehydrogenase 1B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of Malate dehydrogenase 1B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Malate dehydrogenase 1B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Malate dehydrogenase 1B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Malate dehydrogenase 1B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008051 ID=SMED30008051|Name=Malate dehydrogenase 1B|organism=Schmidtea mediterranea sexual|type=transcript|length=1950bpback to top protein sequence of SMED30008051-orf-1 >SMED30008051-orf-1 ID=SMED30008051-orf-1|Name=SMED30008051-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=612bp MAKIVVAGCSDCPYFAKVELLADNLKINVPNFHVHKIVKTRKEWSAWSSEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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