Coiled-coil domain-containing protein 22 homolog

Overview
NameCoiled-coil domain-containing protein 22 homolog
Smed IDSMED30008044
Length (bp)1918
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Coiled-coil domain-containing protein 22 homolog (SMED30008044) t-SNE clustered cells

Violin plots show distribution of expression levels for Coiled-coil domain-containing protein 22 homolog (SMED30008044) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Coiled-coil domain-containing protein 22 homolog (SMED30008044) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Coiled-coil domain-containing protein 22 homolog (SMED30008044) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008044

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30008044h1SMcG0013981 dd_Smed_v4_5400_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30008044h1SMcG0013981 dd_Smed_v4_5400_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Human
Match: CCDC22 (coiled-coil domain containing 22 [Source:HGNC Symbol;Acc:HGNC:28909])

HSP 1 Score: 98.5969 bits (244), Expect = 8.497e-21
Identity = 83/252 (32.94%), Postives = 141/252 (55.95%), Query Frame = 3 
Query:  966 ESEKAKSITRRKIALILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESL 1721
            E E+A  +  R + L L +G  NL KL+L +     ++ ++  QW+ H+  L  E + +   +  ++  +S+   +LA++++    L ++ R    E +  +E  KQ++   +   +  +R  +T+RILE+  N +KQKEEI KIL    +LQK IN L GKLDR+F    D ++   +KKD+  ++ +  L  +HENCS+L+  IE+ G ++RE+R+++  IE E  +    NLEKI  DY   +Q    L
Sbjct:  378 EREQALRLKSRAVEL-LPDGTANLAKLQLVVENSAQRVIHLAGQWEKHRVPLLAEYRHLRKLQDCRELESSR---RLAEIQE----LHQSVRAAAEEARRKEEVYKQLMSELETLPRDVSRLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFA-VTDELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETELGKKTLSNLEKIREDYRALRQENAGL 620

HSP 2 Score: 87.8113 bits (216), Expect = 2.185e-17
Identity = 50/172 (29.07%), Postives = 83/172 (48.26%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSVPFSQYSAKSLLIPFKSDR 536
            M+EAD+ILI SL   G  +     +L  F+ ++++ A   CL  I  +           P+ + +R+++  +L++A   LGY   +GYQ FLYP+  D R ++ FL E LP +          +S  + + I +   +    PW+P + R   +   Q SA  L  PF + R
Sbjct:    1 MEEADRILIHSLRQAGTAVPPDVQTLRAFTTELVVEAVVRCLRVINPAVGS--GLSPLLPLAMSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDADQPAGDSAILLRAIGSQIRDQLALPWVPPHLRTPKLQHLQGSA--LQKPFHASR 168
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Fly
Match: CG9951 (gene:FBgn0036671 transcript:FBtr0075337)

HSP 1 Score: 95.1301 bits (235), Expect = 3.776e-20
Identity = 49/157 (31.21%), Postives = 81/157 (51.59%), Query Frame = 3 
Query:   21 MDEADKILIESL--ISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKET-----GPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCR 470
            MDE DKI++  L  +   +E TD    L +F+P+ ++ A   CL  I      P++ P      +  R+ V  +L++  K  GY+  +GYQ FLYPN  + R+++ FLIE LP+E      G S    L+    + + I+   ++   +PW+P + R
Sbjct:    1 MDEVDKIIMHQLHQVDATIEPTD---ELSDFTPEQVVRAVSGCLAEIRPDLQLPRTLPGGA---MAQRFGVASSLAQGCKDSGYRGDIGYQTFLYPNAVELRRLLMFLIEQLPRERQGTEDGASKSQTLSHRQLLERKIRKELAQQLKTPWVPQFAR 151

HSP 2 Score: 76.2554 bits (186), Expect = 3.858e-14
Identity = 58/218 (26.61%), Postives = 115/218 (52.75%), Query Frame = 3 
Query: 1083 NIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLK 1736
             + +QWQ ++  L + ++ +         +T+K   ++  ++  +E LE+    KT +   L+  ++   ++         R ++T+RI E   N +KQ+ +I K+L     LQK +NV+  +L R F    D +   S+K D  AKR +  L  +H NC+ELV  +   G + ++IRE++  I+ E  ++V  +L++IT D  + +Q+ + L++ ++
Sbjct:  345 TLTQQWQDYRKPLLESLEKL---------KTAKEAQEVQGIRNSIEQLEQELLAKTQQHNELNATLRSASQS------LAPRKEYTRRIHEFIGNIRKQRADIYKVLDDTRQLQKQLNVVGAQLQRQFNYTDDLLFQ-SAKHDLHAKRAYKLLAQLHANCNELVECVSLTGNVTKQIRELEVQIDGEKLKNVLTSLQQITGDIQKFEQHIQELQEQIR 546
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Zebrafish
Match: ccdc22 (coiled-coil domain containing 22 [Source:NCBI gene;Acc:556259])

HSP 1 Score: 103.219 bits (256), Expect = 1.477e-22
Identity = 79/227 (34.80%), Postives = 130/227 (57.27%), Query Frame = 3 
Query: 1059 AKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKD 1739
            +KR  Q+ +   QW+ H+  L  E + + +    +++ +S+   +L+++K     L    R+   E K  +   KQ++   +  +K  +R+ +T RILE+  N KKQKEEI KIL    DLQK IN L GKLDR+F    D ++   +KKDE+ ++ +  L  +HENC++L+  IE+ G ++REIR+++  IE EN +    NLEKI  DY   +Q   +L   +++
Sbjct:  423 SKRVVQLAS---QWEKHRVPLIDEHRRLKELCSNRESESSR---KLSEIK----DLHDKIRQSAEEAKKKESLYKQLLTEFETLSKDVSRSAYTIRILEIVGNIKKQKEEITKILSDTKDLQKEINGLTGKLDRTFA-VTDELVFKDAKKDESVRKSYKYLAALHENCTQLIQTIEDTGTIMREIRDLEEQIETENGKRTVSNLEKILEDYKAIRQENSALAAKIRE 638

HSP 2 Score: 98.5969 bits (244), Expect = 5.573e-21
Identity = 51/174 (29.31%), Postives = 88/174 (50.57%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRI-------QSVPFSQYSAKSLLIP 521
            M+E D+ILI SL   G +I +   S++ F+ ++++ A   CL  I    +       S P  + +R+++G +L++A + +G+K  +GYQ FLY N  + R +  FL+E LP+E+  +      +S  + + I          PWLP  CR+        S P   + A+ L +P
Sbjct:    1 MEEVDRILIHSLRQAGTDIDEDVQSVKQFTSELIVEAVVRCLRVI--DPAVGNGLSHSLPPGMSARFRLGMSLAQACQDVGFKGEIGYQTFLYSNEPEIRSLFMFLVERLPRESAEASDQPAGKSVLLQRAIAAQIKAQLSVPWLPPTCRLPVHRKTQSSGPCHSFHAQPLSLP 172
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Xenopus
Match: ccdc22 (coiled-coil domain containing 22 [Source:NCBI gene;Acc:448468])

HSP 1 Score: 103.605 bits (257), Expect = 1.802e-22
Identity = 73/211 (34.60%), Postives = 122/211 (57.82%), Query Frame = 3 
Query: 1074 QIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQ 1706
            ++ N+  QW++H+  L++E + +   +++++  +S+    + D K   E ++        E K  +E  KQ++   +   K  +R  +T+RILE+  N KKQKEEI KIL    +LQK IN L GK+DR+F+   + +    +KKDE  ++ +  L  +HENCS+L+  IE+ G ++REIR+++  IE E  +    NL+KI  DY   KQ
Sbjct:  411 RMANLVGQWESHQVRLSEEYRELKRVQQEQEDESSRW---MKDAKDLYEKIQG----AADEAKRKEELYKQLLSEYESLPKEVSRAAYTQRILEIVSNIKKQKEEITKILSDTKELQKEINNLTGKVDRTFVVTDELVFK-DAKKDEPVRKAYKYLAALHENCSQLIQTIEDTGTILREIRDLEEQIETETTKKTLSNLQKILEDYRAIKQ 613

HSP 2 Score: 81.6481 bits (200), Expect = 1.473e-15
Identity = 42/138 (30.43%), Postives = 71/138 (51.45%), Query Frame = 3 
Query:   93 SLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSVPFSQYSAK 506
            S+  F+ ++++ A   CL  I  + S   +     P  + +R+++G +L++A + LGY   VGYQ FLY +  D R ++ FL E LP+++         +S  + + I  T       PWLP  CRI ++  SQ S +
Sbjct:   13 SIRQFNTELIVEAVVRCLRVI--NPSLGATLSHVLPPGMSARFRIGTSLAQACQDLGYPGEVGYQTFLYSSEPDIRALLIFLAEKLPRDSPEDAHQPAGKSALLQREIAATIKRQLSLPWLPSSCRICALRRSQNSCR 148
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Xenopus
Match: ccdc22 (coiled-coil domain containing 22 [Source:NCBI gene;Acc:448468])

HSP 1 Score: 103.219 bits (256), Expect = 2.064e-22
Identity = 91/290 (31.38%), Postives = 158/290 (54.48%), Query Frame = 3 
Query:  882 NTLLDKFDKLNEKFNKLSLSDKQLDVEL---------------ESEKAKSITRRKIALILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQ 1706
            ++L ++ D + ++   LS S+K+L + +               E EK   + +R + L L + + NL KL+  +     ++ N+  QW++H+  L++E + +   +++++  +S+    + D K   E ++        E K  +E  KQ++   +   K  +R  +T+RILE+  N KKQKEEI KIL    +LQK IN L GK+DR+F+   D ++   +KKDE  ++ +  L  +HENCS+L+  IE+ G ++REIR+++  IE E  +    NL+KI  DY   KQ
Sbjct:  340 SSLQEQIDSIEQEIRGLSESNKRLQLTVSQVEGEVNEMRQSCEEKEKIVRVKKRAVEL-LPDADNNLVKLQALVDASSHRMANLVGQWESHQVRLSEEYRELKRVQQEQEDESSRW---MKDAKDLYEKIQG----AADEAKRKEELYKQLLSEYESLPKEVSRAAYTQRILEIVSNIKKQKEEITKILSDTKELQKEINNLTGKVDRTFV-VTDELVFKDAKKDEPVRKAYKYLAALHENCSQLIQTIEDTGTILREIRDLEEQIETETTKKTLSNLQKILEDYRAIKQ 620

HSP 2 Score: 101.293 bits (251), Expect = 1.002e-21
Identity = 53/162 (32.72%), Postives = 86/162 (53.09%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSVPFSQYSAK 506
            M+E D+ILI SL S G E+ +   S+  F+ ++++ A   CL  I  + S   +     P  + +R+++G +L++A + LGY   VGYQ FLY +  D R ++ FL E LP+++         +S  + + I  T       PWLP  CRI ++  SQ S +
Sbjct:    1 MEEVDRILIHSLRSCGTEVPEDVQSIRQFNTELIVEAVVRCLRVI--NPSLGATLSHVLPPGMSARFRIGTSLAQACQDLGYPGEVGYQTFLYSSEPDIRALLIFLAEKLPRDSPEDAHQPAGKSALLQREIAATIKRQLSLPWLPSSCRICALRRSQNSCR 160
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Mouse
Match: Ccdc22 (coiled-coil domain containing 22 [Source:MGI Symbol;Acc:MGI:1859608])

HSP 1 Score: 100.908 bits (250), Expect = 8.392e-22
Identity = 84/247 (34.01%), Postives = 138/247 (55.87%), Query Frame = 3 
Query:  966 ESEKAKSITRRKIALILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQ 1706
            E E+A  +  R + L L +G  NL KL+L +     ++ ++  QW+ H+  L  E + +   +R +  R  +   +LA++++    L  + R    E +  +E  KQ++   +   K  +R  +T+RILE+  N +KQKEEI KIL    +LQK IN L GKLDR+F    D ++   +KKD+  ++ +  L  +HENCS+L+  IE+ G ++RE+R+++  IE E  +    NLEKI  DY   +Q
Sbjct:  378 EQEQALRLKSRTVEL-LPDGAANLAKLQLVVESSAQRLIHLASQWEKHRVPLLAEYRHL---RRLQDCRELESSRRLAEIQE----LHHSVRAAAEEARRKEEVYKQLVSELETLPKDVSRLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFA-VTDELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETEMGKKTLSNLEKICEDYRALRQ 615

HSP 2 Score: 88.1965 bits (217), Expect = 1.144e-17
Identity = 63/226 (27.88%), Postives = 101/226 (44.69%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSVPFSQYSAKSLLIPFKSDR--KPSLND----W-FNSFPTI---DKQVDRFDEFLFLAINYDLKTRICENINPD 668
            M+EAD+ILI SL   G  +     +L  F+ ++++ A   CL  I              P  + +R+++  +L++A   LGY   +GYQ FLYP+  D R ++ FL E LP +          +S    + I +   +    PW+P   R   V   Q SA  L  PF S R   P LN     W F + P +     QV +        + +   +++C+++N D
Sbjct:    1 MEEADRILIHSLRQAGTAVPPEVQTLRAFTTELVVEAVVRCLRVINPDVGS--GLSHLLPPAMSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPSDASEDADQPAGDSAIFLRAIGSQIRDQLALPWVPPLLRTPKVQRLQGSA--LQQPFHSSRLVLPELNSSGELWEFQASPLLLPAPTQVPQLQGRAASLLEHH-ASQLCQHVNRD 221
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. UniProt/SwissProt
Match: sp|Q16VW9|CCD22_AEDAE (Coiled-coil domain-containing protein 22 homolog OS=Aedes aegypti OX=7159 GN=AAEL009388 PE=3 SV=1)

HSP 1 Score: 166.777 bits (421), Expect = 5.324e-43
Identity = 154/613 (25.12%), Postives = 287/613 (46.82%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQ-SFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQI---IKNTFSENWMSPWLPHYCRI---------------QSVPFSQYSAKSLLIPF--KSDRKPSLNDWFNSFPTIDKQVDRFDEF-----LFLAINYDLKTRICENINPDNLTKIIKEMNSTKSEQIINERLNQSKPEVRKRTKFIEKKSENVDDXXXXXXXXXXXXXXXXXRFDEIVTIYNTLLDKFDKL-------NEKFNKLSLSDKQLDVELESEKAKSITRRK--------IALILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLK 1736
            MDE D I++ SL  +   + +  +SL++ SP +L+     C+  I     +P    P++ P  +  R+    +L+EA +++GY+  +GYQ FLY N+ + R+++ FL+E LPKE            +  TQ+   I ++      +PW+P +C++                 + F ++  + + +PF  + D    + ++++      + +D  DE      L  A +  +KT         N    I E++       INE+L Q   +   + +  E                 N    T+       T   +L ++ D L       +E+  +L  S K+ D  +E E  K+I R K          ++L + E N++KLE  IA    ++  ++ QW AH+  L   +++   +   K +++ ++  Q+   +Q+ E +  + + K +    L ++ +++       NK  +R  +T RILE+  N +KQK  I +IL     LQK IN + G+LDR F    D +   ++KKDE +KR +  L+ +H +C EL+ +++E G + RE+R+++  IENE   +   NL +IT D  E +   + L++ ++
Sbjct:    1 MDEIDNIILHSLRQIECNLDEEVISLDDLSPSMLVQVVSKCISLI-----DPGLELPRTLPPGMAQRFTATASLAEACRTIGYRRDIGYQTFLYSNVAEVRRVLMFLVEKLPKEAADKTSGSGQPVDSATQLENRILSSLQSQLQAPWMPEFCQVGRPEGLSTTSGGESPAQIAFRRFIPRKISVPFVTQGDVAAEVKEFWSR-----RNLDCLDEGSLVPSLIAANDGAIKT---------NAKGAIDEVDRQVKLPAINEKLLQYYSKGGTKHRLAEPSGAAASSGTTEKVVLNNITVETKPGK----TPLESLQEEIDALQQEIVQHSEEGVQLESSRKETDESIE-EYRKTIVRLKEEKKIKERTHILLEDPEVNVKKLEAIIAAGGERMKKLQDQWDAHRIPLVDTLEAYRLKNSDKLSKSQQVLDQIESTRQKCEEVVIDLQTKGAMYARLQKEFEKL-------NKTVSRTAYTSRILEIIGNIRKQKNGIDQILQDTRSLQKEINNITGQLDRQFTVTDDLIFR-NAKKDEHSKRAYKLLVTLHSDCEELIKLVQETGAIKREVRDLEDQIENEKGRNTAANLAQITHDLTEMQNESQRLEESIR 581
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. UniProt/SwissProt
Match: sp|Q8I145|CCD22_DROWI (Coiled-coil domain-containing protein 22 homolog OS=Drosophila willistoni OX=7260 GN=GK20894 PE=3 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 4.923e-36
Identity = 146/596 (24.50%), Postives = 269/596 (45.13%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKET-----GPSVIDRLNESNDITQIIKNTFSENWMSPWLPHY-----------CRIQSVPFSQYSAKSLLIPFKSDRKPSLNDWFNS-FPTIDKQVDRFDEFLFLAINYDLKTRICE-----------NINPDNLTKIIKEMNSTKSEQIINERLNQSKPEVRKRTKFIEKKSENVDDXXXXXXXXXXXXXXXXXRFDEIVTIYNTLLDKFDKLNEKFNKLSLSDKQLDVELESEKAKSITRRKIALILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLK 1724
            MDE DKI++  L  +   I   E  L NF+P +++ A   CL+ I +S  +    P+S P+ +  R+ V   L+E  +  GY+  +GYQ FLYPN  + R+++ FLIE LP+E             L+    + + I+         PW+P +           C  Q + F      ++      DR   +  +F+   P + +Q          A  YDL   +             +++P  LT        + S+ ++ + L  S     + +   EK +++               E+  +   E+ T    +L+    +  K N+L + +     E E+ ++K  +  K++L+LS  EEN+ KLE  +     +   + +QWQ ++  L   + ++ + +  +Q +          ++  +E LE+    K+ +   L+  +K   ++         R ++T+RI E  +N +KQ+E+I K+L     LQK +NV+  +L R F    D +   S+K D  AK+ +  L  +H NCSELV  +   G + +EIR+++  I+ E  ++V   L++IT D   ++Q+ + L+
Sbjct:    1 MDEVDKIIMHQLHQIDASIEPTE-ELANFTPALVVRAVASCLQEISQSLKD---LPRSLPMAMAQRFNVATILAERCQESGYRGDIGYQTFLYPNPVELRRLLMFLIEQLPRERQSEDDANRTSHPLSSREQLERQIRQKLKAQLKMPWVPQFCRMVANRKSLGCNSQCISFEPQLNLNVPSANPEDRSKEVQQYFDQQAPNLFQQTS--------ANCYDLIASVMHKNDLERWGDLPSMDPVTLT--------STSDDLVGKALPTSP---TQTSTTAEKAAQDNSSEATATSTTTTPLELLGQEVQELRTQTEIMLNHRKMVTSKLNELKIRETTASQEKETIESKLKSHEKLSLVLSEPEENVGKLEALVEATENKRQTLNQQWQDYRRPLLDTLSTLRNAQEAQQVQI---------IRNSIEKLEQEIIAKSQQHNELNSSLKNATQSVA------PRQEYTRRIHEFIKNIRKQREDIFKVLDDTRQLQKQLNVVNAQLQRQFNYTDDLLFQ-SAKHDLHAKKAYKLLAQLHSNCSELVECVSLTGNVTKEIRDLEVQIDGEKLKNVLSRLQQITGDIQRSEQHIQELQ 557
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. UniProt/SwissProt
Match: sp|A7RNG8|CCD22_NEMVE (Coiled-coil domain-containing protein 22 homolog OS=Nematostella vectensis OX=45351 GN=v1g180167 PE=3 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 6.627e-26
Identity = 80/221 (36.20%), Postives = 132/221 (59.73%), Query Frame = 3 
Query: 1083 NIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKDYK 1745
            N+ +QW+ H++ L  E + +      K + T K   +L ++K    SL +  +E   E +  D+  KQ++   ++ ++  NR+ +T+RILE+  N KKQKEEI KILV    +QK IN L GKLDR+F    D ++   +KKDE  ++ +  L  +HENC EL+  +E+ G ++REIR+++  I+ E++ +   NLE+ITAD+ + K+   +L K +K  K
Sbjct:  430 NLAQQWETHRTALIDEYRELKVINANKVSETQK---KLEEIK----SLREKMKEVAEETRGKDDLYKQLVSEYERMSRDVNRSAYTRRILEIVGNIKKQKEEINKILVDTKSVQKEINQLSGKLDRTFT-VTDELIFRDAKKDEACRKAYKYLASLHENCKELIQAVEDTGVIMREIRDLEEQIDTESQRNTANNLERITADHKQMKEENATLTKKIKALK 642

HSP 2 Score: 102.064 bits (253), Expect = 2.904e-21
Identity = 49/156 (31.41%), Postives = 85/156 (54.49%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSVPF 488
            M+E D I+I +L  +G EI +   SL  F+  +++ A+  CL  I    +E    P + P ++ ++++VG  L+ A++ LGY+  +GYQ FLY N KD R +  FL+E LPKET  +  + L  S  + + + +  ++     W P + +   V +
Sbjct:    1 MEEVDNIIIHTLRQIGCEIPEEIQSLREFTTTVIVQASSKCLHVI----NEDIDIPSNLPSSMSAKFRVGTMLAAALQDLGYRGEIGYQTFLYSNEKDIRSVFMFLVEHLPKETSLAASEPLGSSVLLNRRVASDLAQRLTLSWTPTFLKKGGVRW 152
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. UniProt/SwissProt
Match: sp|B0WTU5|CCD22_CULQU (Coiled-coil domain-containing protein 22 homolog OS=Culex quinquefasciatus OX=7176 GN=CPIJ010681 PE=3 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 7.000e-26
Identity = 55/177 (31.07%), Postives = 92/177 (51.98%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDR---LNESNDITQIIKNTFSENWMSPWLPHYCRIQSVP------FSQYSAKSLLIPF 524
            MDE D I++ SL  +G  + D   SL+ FSP +L+     C+  I  S       P++ P  +  R+    +L+EA +++GY+  +GYQ FLY N+ + R+++ FLIE LPKE+          L+ + ++   I  +      +PW+P +CR  + P      F ++  + L IPF
Sbjct:    1 MDEIDNIILHSLRQIGCTLDDEVTSLDEFSPTLLVQVVSKCITLIDSSLD----LPRTLPPGMAQRFTATASLAEACRTIGYRRDIGYQTFLYSNVAEVRRVLMFLIERLPKESADKAAGTGQPLDVTTELESRICASLQSQLQAPWMPEFCRTAAGPSSSQIAFRRFVPRKLNIPF 173

HSP 2 Score: 93.9745 bits (232), Expect = 1.031e-18
Identity = 65/221 (29.41%), Postives = 124/221 (56.11%), Query Frame = 3 
Query: 1086 IERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKDYKR 1748
            ++ QW  H+  L QE++    +   K +++ ++  Q+   + + E +  + + K++    L ++++++       N+  +R  +T RILE+  N +KQK +I KIL     LQK IN + G+LDR F    D +   ++KKDE AK+ +  L+ +H +C+EL+++++E G + REIR+++  IE E   +   NL +I  D  E +   + L++ L+ + R
Sbjct:  359 LQDQWDVHRIPLEQELEGYRVKHSDKLSQSQQIVDQIEATRHKSEEVMMDLQTKSAMHARLQKELEKL-------NRTVSRTAYTSRILEIVGNIRKQKTDIDKILQDTRTLQKEINTITGQLDRQFTVTDDLIFR-NAKKDEHAKKAYKLLVTLHSDCAELMALVQETGAVKREIRDLEDQIETERSRNTAANLAQICRDLAEMQSESQRLEESLRAHLR 571
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. UniProt/SwissProt
Match: sp|Q28G12|CCD22_XENTR (Coiled-coil domain-containing protein 22 OS=Xenopus tropicalis OX=8364 GN=ccdc22 PE=2 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 2.610e-22
Identity = 92/290 (31.72%), Postives = 158/290 (54.48%), Query Frame = 3 
Query:  882 NTLLDKFDKLNEKFNKLSLSDKQLDVEL---------------ESEKAKSITRRKIALILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQ 1706
            ++L ++ D + ++   LS S+K+L + +               E EK   + +R + L L + + NL KL+  +     ++ N+  QW++H+  L++E + +   +++++  +S+    + D K     L +  R    E K  +E  KQ++   +   K  +R  +T+RILE+  N KKQKEEI KIL    +LQK IN L GK+DR+F+   D ++   +KKDE  ++ +  L  +HENCS+L+  IE+ G ++REIR+++  IE E  +    NL+KI  DY   KQ
Sbjct:  340 SSLQEQIDSIEQEIRGLSESNKRLQLTVSQVEGEVNEMRQSCEEKEKIVRVKKRAVEL-LPDADNNLVKLQALVDASSHRMANLVGQWESHQVRLSEEYRELKRVQQEQEDESSRW---MKDAK----DLYEKIRGAADEAKRKEELYKQLLSEYESLPKEVSRAAYTQRILEIVSNIKKQKEEITKILSDTKELQKEINNLTGKVDRTFV-VTDELVFKDAKKDEPVRKAYKYLAALHENCSQLIQTIEDTGTILREIRDLEEQIETETTKKTLSNLQKILEDYRAIKQ 620

HSP 2 Score: 101.293 bits (251), Expect = 5.261e-21
Identity = 53/162 (32.72%), Postives = 86/162 (53.09%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSVPFSQYSAK 506
            M+E D+ILI SL S G E+ +   S+  F+ ++++ A   CL  I  + S   +     P  + +R+++G +L++A + LGY   VGYQ FLY +  D R ++ FL E LP+++         +S  + + I  T       PWLP  CRI ++  SQ S +
Sbjct:    1 MEEVDRILIHSLRSCGTEVPEDVQSIRQFNTELIVEAVVRCLRVI--NPSLGATLSHVLPPGMSARFRIGTSLAQACQDLGYPGEVGYQTFLYSSEPDIRALLIFLAEKLPRDSPEDAHQPAGKSALLQREIAATIKRQLSLPWLPSSCRICALRRSQNSCR 160
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. TrEMBL
Match: A0A154P9V2 (Coiled-coil domain-containing protein 22 like protein OS=Dufourea novaeangliae OX=178035 GN=WN55_09061 PE=4 SV=1)

HSP 1 Score: 207.223 bits (526), Expect = 5.768e-55
Identity = 174/597 (29.15%), Postives = 311/597 (52.09%), Query Frame = 3 
Query:   18 VMDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQ--------SVPFSQYSAKSLLIPFKSDRKPSLNDWFNSFPTIDKQVDRFDEFLFLAINYDLKTRICENINPDNLTKIIKEMNSTKSEQIINERLNQ--------SKPEVRKRTKFIEKKSENVDDXXXXXXXXXXXXXXXXXRFDEIVTIYNTLLDKFDKLNEKFNKLSLSDKQLDVELESEKAKSIT----RRKIAL----ILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLK 1736
            +M+E D I+I SL  +G +I +   +L  F+ ++++ AT  CL+ I              P+N+ +R+++G TL++A   LGYK  +GYQ FLY +  D R++  FLIE LPKE   ++ + ++    + + I     +    PWLPHYC  +        SVP   Y + SL +P     +   N   +    + KQV     FL   I+Y+ K     +  P NL   I  +N  +SE+ I+   ++        S  +    +K ++ K  NV       +E  N+ +  +   ++I      L    ++L ++  KLS S  Q+ +  ++E+ K +T    ++KI +    +L +GEE+++KLE+ I     ++ ++  QW+ H+  L   IQ    ++ +  T+ S  + +L ++K     L++  RE   E ++ D++  Q++    +  K  NR+ +T+RILE+  N +KQ++EI K+L    ++QK IN L G+++RSF    + +    ++ +E +++ +  L  +H +CSELVS++EE G  IREIR+++  I++E+ ++V  NLE+ITAD  + KQ    L   L+
Sbjct:    1 MMEEVDNIIIHSLRQIGCDIKENITNLGGFTTELVVEATIRCLDIIRPG----LGVSTILPINMAARFRLGATLAQACADLGYKGDIGYQTFLYSSEVDLRRVFMFLIEKLPKECDKTLNEPISNVALLEKSIAAAVLQGLSVPWLPHYCHTKGFRNRGRASVP---YVSISLEVPTTKSEEEYQNYCIHYLQPVPKQVQNPQSFLPSLISYNAKAL---HPKPMNLLDRINWLNKIQSEKAIDTNASKDANVLNRVSIKDTTLTSKQLQAKEVNVAKPVLPKQETLNKVKKQKLEVEKIKVECEILRSNMEELQDEIKKLSTSITQITINYQNEE-KELTINEEQKKIKVRIYDLLQDGEESIKKLEIAIESTTNKLISLGNQWEKHRVPL---IQKYRQEREKHSTKASASQKKLDEIK----LLKERERELQEECRNKDQQYSQLVAEVQKLPKEVNRSAYTQRILEIINNVRKQRDEINKVLADTREIQKEINTLTGRVERSFTVVDELIFR-DARTNEASRKAYKLLATLHSDCSELVSLVEETGATIREIRDLEEQIDSESTKNVGANLERITADLKQMKQETAVLTAQLQ 578
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. TrEMBL
Match: A0A0L7R2I8 (Coiled-coil domain-containing protein 22 OS=Habropoda laboriosa OX=597456 GN=WH47_04633 PE=4 SV=1)

HSP 1 Score: 195.667 bits (496), Expect = 8.623e-51
Identity = 171/606 (28.22%), Postives = 310/606 (51.16%), Query Frame = 3 
Query:   18 VMDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYC-----RIQSVPFSQYSAKSLLIPFKSDRKPSLNDW-FNSFPTIDKQVDRFDEFLFLAINYDLK------TRICENIN------PDNLTKI-IKEMNSTKSEQIINERLNQSKPEVR----KRTKFIEKKSENVDDXXXXXXXXXXXXXXXXXRFDEIVTIYNTLLDKFDKLNEKFNKLSLSDKQLDVELESEKAKSIT--------RRKIALILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQ-TRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKD 1739
            +M+E D I+I SL  +G +I +   +L  F+ ++++ AT  CL+ I              P+N+ +R+++G TL++A   LGYK  +GYQ FLY +  D RK+  FLIE LPKE+   + + ++    + + I +  S+   +PWLPH+C     R +      Y + +L +P   +      D+  +   ++ +QV      L   I+Y+ +      T I + IN       D +T++ I   N      I +  L  ++ +++    + TK  E+K               ++ E  +   + I      L D  ++L +   KL+ S  Q+ +  ++E+ K +T        + +I  +  +GEEN++KLE  I     ++ N+  QW+ H+  L Q+ +    Q+R+K  T+ S  + +L ++K     L++  RE   E ++ D++  Q++    +  K  NR+ +T+RILE+  N +KQ++EI K+L    ++QK IN L G+L+RSF    + +    ++ +E +++ +  L  +H +CSELV ++EE G  IREIR+++  I++E  ++V  NLE+ITAD  + KQ    L   L++
Sbjct:    1 MMEEVDNIIIHSLRQIGCDIEENITNLSGFNTELVVEATIKCLDII----KSGLGLSTVLPINMAARFRLGATLAQACSDLGYKGDIGYQTFLYSSEADLRKVFMFLIEKLPKESDKPLSEPVSNIALLEKSIASAISQGLSAPWLPHFCHTKGFRNKGRARVSYKSINLEVPKLQELSAEYQDYCIHYLQSVPEQVQNQSSVLPSLISYNARALHLHSTSILDQINWLNKQHCDKITEVNISGDNVLNRVSIKDTTLASNESQIKNNGTRETKLTEQK-------------ILDKVEKQDLHVERIKVECEDLRDDIEELQDTIKKLTTSVTQVTINYQNEE-KELTINEEQKKIKARIYDLFQDGEENIKKLEAAIEATTNKLINLGNQWEKHRVPLIQKYR----QEREKHSTKASASQKKLDEIK----LLKEKERELQEECRNKDQQYSQLVSEVQKLPKEVNRSAYTQRILEIINNIRKQRDEINKVLADTREIQKDINTLTGRLERSFTVVDELIFR-DARTNEASRKAYKLLATLHSDCSELVGLVEETGATIREIRDLEEQIDSETTKNVGANLERITADLKQMKQETAELTAQLQN 579
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. TrEMBL
Match: A0A026W2Z7 (Coiled-coil domain-containing protein 22-like protein OS=Ooceraea biroi OX=2015173 GN=DMN91_008877 PE=4 SV=1)

HSP 1 Score: 194.512 bits (493), Expect = 2.328e-50
Identity = 171/597 (28.64%), Postives = 301/597 (50.42%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSV-----PFSQYSAKSLLIPFKS---DRKPSLNDWFNSFPTIDKQVDRFDEFLFLAINYDLKT------RICENINPDNLTKIIKEMNSTKSEQIINERLNQSKPEVRKRTKF-IEKKSENVDDXXXXXXXXXXXXXXXXXRFDEIVTIYNTLLDKFDKLNEKFNKLSLSDKQLDVELE--------SEKAKSITRRKIALILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQK-QTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKD 1739
            M+E D I+I SL  +G +I +   +L  F+ ++++ AT  CLE I              PVN+ +R+++G TL++    LGY+  +GYQ FLY +  D R++  FLIE LPKE+  +V + +++   + + + +  S     PWLPHYC  + V       + Y++ ++ +P  +   D K     +    P    Q+     FL   I+Y+ +T       + E +N  N  +   E   + +  I+NE  N+   E + R+    + KSE+        +E        E   + +      L    D+L  +  KL     Q  V  +        SE+ K +  R   L L +G EN++KLE  I     ++ ++  QW+ H+  L  + +    Q+R+K  T+ +  + +L ++K     L++  RE   E +  D++  Q+I    +  K  NR+ +T+RILE+  N +KQ++EI K+L    ++QK IN L G+L+RSF    + +    ++ +E +++ +  L  +H +CSELV+++EE G  IREIR+++  I++E+ ++V  NLE+ITAD  + KQ   +L   L++
Sbjct:    1 MEEIDNIIIHSLRQIGCDIDESVTNLSGFNTELVVEATVRCLETIRPG----LGLSTVLPVNMAARFRLGATLAQTCTELGYRGDIGYQTFLYNSEADLRRVFMFLIEKLPKESEKTVNESVSKVALLEKSVASAISHALSIPWLPHYCHKRGVRNRGRASTPYASVNIEVPVANAGDDHKDYYTRYLQPVP---HQMQNISCFLPSLISYNARTLGTPSMDLVERVNWLNSQQQQSEKAYSNAHNIVNE-FNKFSSENKARSATESQMKSESTTHSVLPNQETLKTEARQEIELENMRKECEDLRIDMDELQNEIKKLISRLAQATVAAQNDEKELRISEEQKKLKARAFEL-LQDGPENVKKLESAIEASTNKLISLANQWEKHRVPLIMKYR----QEREKYSTKANASQKKLDEIKL----LKEKERELQEECRIKDQQYSQLIAEVQKLPKEVNRSAYTQRILEIINNVRKQRDEISKVLADTREIQKEINTLTGRLERSFTVVDELIFR-DARTNEASRKAYKFLATLHSDCSELVNLVEETGATIREIRDLEEQIDSESAKNVGANLERITADLKQMKQESAALTAQLQN 579
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. TrEMBL
Match: E2BUK9 (Coiled-coil domain-containing protein 22-like protein OS=Harpegnathos saltator OX=610380 GN=EAI_04202 PE=4 SV=1)

HSP 1 Score: 192.586 bits (488), Expect = 1.160e-49
Identity = 170/603 (28.19%), Postives = 314/603 (52.07%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYC-----RIQSVPFSQYSAKSLLIPFKS---DRKPSLNDWFNSFPTIDKQVDRFDEFLFLAINYDLKTRICENINPDNLTKIIKEMNSTKSEQ--------IINE-------------RLNQSKPEVRKRTKFIEKKS-ENVDDXXXXXXXXXXXXXXXXXRFDEIVTIYNTLLDKFDKLNEKFNKLSLSDKQLDVELE-SEKAKSITRRKIALILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLK 1736
            M+E D I++ SL  +G +I +   +L  F+ ++++ AT  CLE I              PVN+ +R+++G TL++    LGY+  +GYQ FLY +  D R++  FLIE LPKE+  ++ + +++   + ++I +  S+  + PWLPHYC     R +    + Y++ ++ +P  S   D K     +    P    Q+     FL   I+Y+ +     N    ++T+ I  +NS +SE+        I++E             + +Q KP+    +   ++++ +NV   E  IE  + E E      +E       L ++  KL  +  + +++ +  + EL+ SE+ K I  R   L L +G EN++KLE  I     ++ N+  QW+ H+  L    +    Q+R+K +  +    +  D  + ++  EK  +E   E ++ D++  Q++    +  +  NR+ +T+RILE+  N +KQ++EI K+L    ++QK IN+L G+++RSF    + +    ++ +E +++ +  L  +H +C+ELVS++EE G  IREIR+++  I+ E+ ++V  NLE+ITAD  + KQ   +L   L+
Sbjct:    1 MEEIDNIIVHSLRQIGCDIEESVTNLSGFNTELVVEATVRCLEAIRPG----LGLSTVLPVNMAARFRLGATLAQTCMELGYRGDIGYQTFLYNSEADLRRVFMFLIEKLPKESEKTINESMSKIALLEKLIASAISQGLLIPWLPHYCHKREFRNRGRANTSYTSVNIEVPVASVEDDYKDYNMRYLQPVP---DQMQNISCFLPSIISYNARAL---NTCSVDITERINWLNSQQSEKNVYPNASNIVSELSKFSSDNKAQISKDSQVKPKSATHSVLPDQETLKNVAKQEVEIESMKVECESLRLNIEE-------LQNEIKKLTTRLAQATVTSQNEEKELKTSEEQKKIKARTYEL-LQDGPENIKKLESIIEASTNKLINLANQWEKHRVPLIIRYR----QEREKHSTKANASQKKLDEIKLLKEREKELQE---ECRNKDQQYSQLVAEVQKLPREVNRSAYTQRILEIINNVRKQRDEISKVLADTREIQKEINMLTGRVERSFTVVDELIFR-DARTNEASRKAYKLLATLHSDCNELVSLVEETGATIREIRDLEEQIDTESTKNVGANLERITADLKQMKQETAALTAQLQ 577
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. TrEMBL
Match: A0A310SJS2 (Coiled-coil domain-containing protein 22 like protein OS=Eufriesea mexicana OX=516756 GN=WN48_07824 PE=4 SV=1)

HSP 1 Score: 190.66 bits (483), Expect = 4.798e-49
Identity = 177/606 (29.21%), Postives = 313/606 (51.65%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQ-SFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQS--------VPFSQYSAKSLLIPFKSDRKPSLNDW-FNSFPTIDKQVDRFDEFLFLAINYDLKT------RICENINPDNLTKI--IKEMNSTKSEQIIN----------ERLNQSKPEVRKRTKFIEKKSENVDDXXXXXXXXXXXXXXXXXRFDEIVTIYNTLLDKFDKLNEKFNKLSLS----DKQLDVELESEKAKSITRRKIALILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQK-QTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKD 1739
            M+E D I+I SL  +G +I +   +L  F+ +++I AT  CL  I      P        PVN+ +R+++G TL++A   LGYK  +GYQ FLY +  D RK+  FLIE LPKE+   + + ++    + + I    +++  + WLPHYC  +         VP   Y + +L IP K D K    D+  +   ++ +QV      L   I+Y+ +        I + IN  N      + ++N++ +  ++N           + +Q K    + TK +E+K   + D  K  +    + ++  + F    T    L D    L    ++++++    +K+L +  E +K K+    +I  +  +GEEN++KLE  +     ++ N+  QW+ H+  L Q    I  Q+R+K  T+ S  + +L ++K     L++  RE   E ++ D++  Q++    +  K  NR+ +T+RILE+  N +KQ++EI K+L+    +Q  IN L G+L+RSF    D ++   ++ +E +++ +  L  +H +CSELVS++EE G  IREIR+++  I++E  ++V  NLE+ITAD  + KQ    L   L++
Sbjct:    1 MEEVDNIIIHSLRQIGCDIEENITNLSGFNTELVIEATVKCLNII-----RPGLGLSTILPVNMAARFRLGATLAQACSELGYKGDIGYQTFLYSSEADLRKVFMFLIEKLPKESDKPLSEPVSNIALLEKSIATAIAQSLSASWLPHYCHTKGFRNRGRARVP---YKSVNLEIP-KMDNKEEYQDYSIHYLQSVPEQVQNDSSLLPSLISYNARALHSHSMSILDQINWLNKQHYDKVTDVNASDNVSVLNRVSVKDTTLSSKESQIKDNTSRETKQVEEK---ILDKVKKQDLQIEKVKVECENFR---TDIEELQDAIKNLTTSVSQVTINYQNEEKELTINEEQKKLKA----RIYDLFQDGEENIKKLEAAVEATTNKLINLGNQWEKHRVPLIQ----IYRQEREKYSTKASASQKKLDEIK----LLKEKERELQEECRNKDQQYSQLVTEVQKLPKEVNRSAYTQRILEIINNIRKQRDEIDKVLIDTRQIQIEINTLTGRLERSFT-VVDELIFRDARTNEASRQAYKLLAKLHSDCSELVSLVEETGATIREIRDLEEQIDSEATKNVGANLERITADLKQMKQETAELTAQLQN 578
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Cavefish
Match: ccdc22 (coiled-coil domain containing 22 [Source:NCBI gene;Acc:103042406])

HSP 1 Score: 107.457 bits (267), Expect = 7.134e-24
Identity = 81/227 (35.68%), Postives = 129/227 (56.83%), Query Frame = 3 
Query: 1059 AKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKD 1739
            AKR   + ++  QW+ H++ L  E + + +    ++  +S+   +L+++K     L    R+   E K  +   KQ+I   +   K  +R+ +T RILE+  N KKQKEEI KIL    DLQK IN L GKLDR+F    D ++   +KKDE+ ++ +  L  +HENC++L+  IE+ G ++REIR+++  IE EN +    NLEKI  DY   +Q   +L   ++D
Sbjct:  423 AKR---VVHLAAQWEKHRAPLIDEHRRLKELCSNREMESSR---KLSEIK----DLHDKIRQSAEEAKKKEGLYKQLITEYETLPKDVSRSAYTMRILEIVSNIKKQKEEITKILSDTKDLQKEINGLTGKLDRTFA-VTDELVFKDAKKDESVRKSYKYLAALHENCTQLIQTIEDTGTIMREIRDLEEQIETENGKKTVSNLEKILEDYKAIRQENSALAAKIRD 638

HSP 2 Score: 98.9821 bits (245), Expect = 2.835e-21
Identity = 53/175 (30.29%), Postives = 89/175 (50.86%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRI------QSVPFSQ-YSAKSLLIPF 524
            M+E D+ILI SL   G +I +   S++ FS ++++ A   CL  I            + P  + +R+++G +L++A + LGYK  +GYQ FLY N  + R ++ FL+E LP+E+  +      +S  + + I          PWLP  CR+      QS      + A+ L +P+
Sbjct:    1 MEEVDRILIHSLKQAGTDIDEDVQSVKQFSSELIVEAVVRCLRVIDPGLG--SGLSPTLPPGMSARFRLGMSLAQACQDLGYKGEIGYQTFLYSNEPEIRSLLMFLVEKLPRESAEASDQPAGKSVLLQKAIAAQIKAQLALPWLPPSCRLPLHRKTQSPGLCHSFRAQPLSLPY 173
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Nematostella
Match: EDO47059 (Coiled-coil domain-containing protein 22 homolog [Source:UniProtKB/Swiss-Prot;Acc:A7RNG8])

HSP 1 Score: 116.701 bits (291), Expect = 2.716e-27
Identity = 80/221 (36.20%), Postives = 132/221 (59.73%), Query Frame = 3 
Query: 1083 NIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKDYK 1745
            N+ +QW+ H++ L  E + +      K + T K   +L ++K    SL +  +E   E +  D+  KQ++   ++ ++  NR+ +T+RILE+  N KKQKEEI KILV    +QK IN L GKLDR+F    D ++   +KKDE  ++ +  L  +HENC EL+  +E+ G ++REIR+++  I+ E++ +   NLE+ITAD+ + K+   +L K +K  K
Sbjct:  430 NLAQQWETHRTALIDEYRELKVINANKVSETQK---KLEEIK----SLREKMKEVAEETRGKDDLYKQLVSEYERMSRDVNRSAYTRRILEIVGNIKKQKEEINKILVDTKSVQKEINQLSGKLDRTFT-VTDELIFRDAKKDEACRKAYKYLASLHENCKELIQAVEDTGVIMREIRDLEEQIDTESQRNTANNLERITADHKQMKEENATLTKKIKALK 642

HSP 2 Score: 102.064 bits (253), Expect = 1.190e-22
Identity = 49/156 (31.41%), Postives = 85/156 (54.49%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSVPF 488
            M+E D I+I +L  +G EI +   SL  F+  +++ A+  CL  I    +E    P + P ++ ++++VG  L+ A++ LGY+  +GYQ FLY N KD R +  FL+E LPKET  +  + L  S  + + + +  ++     W P + +   V +
Sbjct:    1 MEEVDNIIIHTLRQIGCEIPEEIQSLREFTTTVIVQASSKCLHVI----NEDIDIPSNLPSSMSAKFRVGTMLAAALQDLGYRGEIGYQTFLYSNEKDIRSVFMFLVEHLPKETSLAASEPLGSSVLLNRRVASDLAQRLTLSWTPTFLKKGGVRW 152
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Medaka
Match: ccdc22 (coiled-coil domain containing 22 [Source:NCBI gene;Acc:101174405])

HSP 1 Score: 98.9821 bits (245), Expect = 2.889e-21
Identity = 78/227 (34.36%), Postives = 130/227 (57.27%), Query Frame = 3 
Query: 1059 AKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKD 1739
            AKR   + N+  QW+  ++ L  E + + +   ++   +S+   +L+++K    SL +     T E K  +E  KQ++   +   +  +R+ +T+RILE+  N KKQKEEI KIL    +LQK IN L GKLDR+F    D ++   +KKDE+ ++ +  L  +HENC++L+  IE+ G ++REIR+++  IE EN      NLE+I  D+   +Q   +L   +K+
Sbjct:  419 AKR---VVNLASQWEKRRAPLIDEHRRLKEICSRQDLDSSR---KLSEIK----SLHEKIHVSTEEAKKKEETYKQLLTELESLPQDASRSAYTQRILEIVSNIKKQKEEITKILSDTRELQKEINSLTGKLDRTFA-VTDELVFKDAKKDESVRKSYKYLAALHENCNQLIQTIEDTGTILREIRDLEEQIETENGNKTVANLERILDDFKAIRQENAALAAKVKE 634

HSP 2 Score: 85.5001 bits (210), Expect = 5.830e-17
Identity = 46/160 (28.75%), Postives = 82/160 (51.25%), Query Frame = 3 
Query:   18 VMDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSEN----WMSP--WLPHYCRIQS 479
            +M+E D+ILI +L  +G E+ +   S+  F+ ++L+     C+  I            S P  + +R++VG +L++A + +GYK  +GYQ FLY +  + R ++ FL+E LP+E+  +      +S  + + I           W+ P   LP +C  QS
Sbjct:    1 MMEEVDRILIHALRQVGTEVDEDVDSIRQFTSELLVEGVVRCIRVI--DPGLGGGLAPSLPPGMSARFRVGMSLAQACQDVGYKGEIGYQTFLYSSEPEIRSLLMFLVEKLPRESAEASAQPSGKSAVLQRAIAAAIRAQLDLAWVPPNCSLPLHCETQS 158
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Medaka
Match: ccdc22 (coiled-coil domain containing 22 [Source:NCBI gene;Acc:101174405])

HSP 1 Score: 98.5969 bits (244), Expect = 3.483e-21
Identity = 77/227 (33.92%), Postives = 127/227 (55.95%), Query Frame = 3 
Query: 1059 AKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKD 1739
            AKR   + N+  QW+  ++ L        D+ R+ +   S+ +   +    +++SL +     T E K  +E  KQ++   +   +  +R+ +T+RILE+  N KKQKEEI KIL    +LQK IN L GKLDR+F    D ++   +KKDE+ ++ +  L  +HENC++L+  IE+ G ++REIR+++  IE EN      NLE+I  D+   +Q   +L   +K+
Sbjct:  400 AKR---VVNLASQWEKRRAPLI-------DEHRRLKEICSRQDLDSSRKLSEIKSLHEKIHVSTEEAKKKEETYKQLLTELESLPQDASRSAYTQRILEIVSNIKKQKEEITKILSDTRELQKEINSLTGKLDRTFA-VTDELVFKDAKKDESVRKSYKYLAALHENCNQLIQTIEDTGTILREIRDLEEQIETENGNKTVANLERILDDFKAIRQENAALAAKVKE 615

HSP 2 Score: 85.1149 bits (209), Expect = 7.242e-17
Identity = 44/156 (28.21%), Postives = 79/156 (50.64%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSVPF 488
            M+E D+ILI +L  +G E+ +   S+  F+ ++L+     C+  I            S P  + +R++VG +L++A + +GYK  +GYQ FLY +  + R ++ FL+E LP+E+  +      +S  + + I           W+P  C   S+P 
Sbjct:    1 MEEVDRILIHALRQVGTEVDEDVDSIRQFTSELLVEGVVRCIRVI--DPGLGGGLAPSLPPGMSARFRVGMSLAQACQDVGYKGEIGYQTFLYSSEPEIRSLLMFLVEKLPRESAEASAQPSGKSAVLQRAIAAAIRAQLDLAWVPPNC---SLPL 151
[Close]
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Planmine SMEST
Match: SMESG000036456.1 (SMESG000036456.1)

HSP 1 Score: 1081.24 bits (2795), Expect = 0.000e+0
Identity = 579/582 (99.48%), Postives = 581/582 (99.83%), Query Frame = 3 
Query:   21 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSVPFSQYSAKSLLIPFKSDRKPSLNDWFNSFPTIDKQVDRFDEFLFLAINYDLKTRICENINPDNLTKIIKEMNSTKSEQIINERLNQSKPEVRKRTKFIEKKSENVDDXXXXXXXXXXXXXXXXXRFDEIVTIYNTLLDKFDKLNEKFNKLSLSDKQLDVELESEKAKSITRRKIALILSNGXXXXXXXXXXIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENXXXXXXXXXXXLVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKDYKRNQQAAQ 1766
            MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSVPFSQYSAKSLLIPFKSDRKPSLNDWFNSFPTIDKQVDRFDEFLFLAINYDLKTRICENINPDNLTKIIKEMNSTKSEQIINERLNQSKPEVRKRTKFIEKKSENVDDIEKTIEEAENEYEITEKRFDEIVTIYNTLLDKFDKLNEKFNKLSLSDKQLDVELESEKAKSITRRKIALILSNGEENLEKLELEIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTS+LEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNK+QNRNDFTKRILELTENKKKQKEEIKKILVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKDYKRNQQA Q
Sbjct:    1 MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKSEPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTRKIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCRIQSVPFSQYSAKSLLIPFKSDRKPSLNDWFNSFPTIDKQVDRFDEFLFLAINYDLKTRICENINPDNLTKIIKEMNSTKSEQIINERLNQSKPEVRKRTKFIEKKSENVDDIEKTIEEAENEYEITEKRFDEIVTIYNTLLDKFDKLNEKFNKLSLSDKQLDVELESEKAKSITRRKIALILSNGEENLEKLELEIAKRRTQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSELEFQLADVKQQMESLEKNFREKTSEIKSLDEKVKQIIKANDQQNKYQNRNDFTKRILELTENKKKQKEEIKKILVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETAKRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNLEKITADYNEAKQNCESLKKLLKDYKRNQQAVQ 582
The following BLAST results are available for this feature:
BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CCDC228.497e-2132.94coiled-coil domain containing 22 [Source:HGNC Symb... [more]
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG99513.776e-2031.21gene:FBgn0036671 transcript:FBtr0075337[more]
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ccdc221.477e-2234.80coiled-coil domain containing 22 [Source:NCBI gene... [more]
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ccdc221.802e-2234.60coiled-coil domain containing 22 [Source:NCBI gene... [more]
ccdc222.064e-2231.38coiled-coil domain containing 22 [Source:NCBI gene... [more]
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Ccdc228.392e-2234.01coiled-coil domain containing 22 [Source:MGI Symbo... [more]
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q16VW9|CCD22_AEDAE5.324e-4325.12Coiled-coil domain-containing protein 22 homolog O... [more]
sp|Q8I145|CCD22_DROWI4.923e-3624.50Coiled-coil domain-containing protein 22 homolog O... [more]
sp|A7RNG8|CCD22_NEMVE6.627e-2636.20Coiled-coil domain-containing protein 22 homolog O... [more]
sp|B0WTU5|CCD22_CULQU7.000e-2631.07Coiled-coil domain-containing protein 22 homolog O... [more]
sp|Q28G12|CCD22_XENTR2.610e-2231.72Coiled-coil domain-containing protein 22 OS=Xenopu... [more]
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A154P9V25.768e-5529.15Coiled-coil domain-containing protein 22 like prot... [more]
A0A0L7R2I88.623e-5128.22Coiled-coil domain-containing protein 22 OS=Habrop... [more]
A0A026W2Z72.328e-5028.64Coiled-coil domain-containing protein 22-like prot... [more]
E2BUK91.160e-4928.19Coiled-coil domain-containing protein 22-like prot... [more]
A0A310SJS24.798e-4929.21Coiled-coil domain-containing protein 22 like prot... [more]
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ccdc227.134e-2435.68coiled-coil domain containing 22 [Source:NCBI gene... [more]
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO470592.716e-2736.20Coiled-coil domain-containing protein 22 homolog ... [more]
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ccdc222.889e-2134.36coiled-coil domain containing 22 [Source:NCBI gene... [more]
ccdc223.483e-2133.92coiled-coil domain containing 22 [Source:NCBI gene... [more]
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BLAST of Coiled-coil domain-containing protein 22 homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000036456.10.000e+099.48SMESG000036456.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008044 ID=SMED30008044|Name=Coiled-coil domain-containing protein 22 homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=1918bp
CTATATAAATCTTATATGTTATGGATGAAGCTGATAAAATCCTGATTGAA
TCATTGATTTCCATGGGATTAGAAATAACAGATCGTGAATTAAGTTTAGA
AAATTTTTCTCCAGATATTTTAATAAATGCAACTGGTCTTTGCTTGGAAT
ATATATTTGAAAGCAAAAGTGAACCACAATCTTTTCCTAAATCTTGCCCA
GTTAATATAGGTAGTCGATACAAAGTTGGTCAAACCTTATCAGAAGCCAT
TAAATCATTAGGATACAAAGATTCAGTTGGTTATCAAGCATTTCTCTACC
CTAATATAAAAGACACAAGAAAAATAATTTCATTTTTAATCGAAACATTA
CCTAAAGAAACTGGTCCATCAGTCATTGACCGATTAAATGAAAGTAATGA
TATCACTCAAATAATTAAAAACACATTTTCCGAAAATTGGATGTCACCTT
GGTTGCCACATTATTGTCGAATTCAATCAGTTCCTTTTTCACAGTATTCC
GCTAAATCTTTATTAATTCCTTTCAAATCAGACAGAAAACCGTCACTAAA
TGATTGGTTTAATTCTTTCCCAACTATCGACAAACAAGTTGATAGATTTG
ATGAATTTCTATTTCTCGCAATCAACTATGATTTAAAAACACGAATCTGT
GAAAATATTAATCCCGATAATTTGACAAAAATTATCAAAGAAATGAATTC
AACAAAATCAGAACAGATAATCAATGAACGATTAAACCAATCGAAACCCG
AAGTGAGAAAACGGACCAAATTTATCGAAAAAAAATCGGAAAATGTTGAT
GATATTGAAAAAACCATCGAAGAAGCCGAAAACGAATACGAAATAACCGA
GAAGAGATTCGATGAAATTGTGACTATTTACAATACGCTGCTTGACAAAT
TCGATAAATTAAACGAAAAATTTAACAAATTATCGTTAAGTGACAAACAA
TTAGACGTTGAACTTGAATCCGAAAAAGCGAAATCGATAACAAGAAGAAA
AATCGCCCTTATTCTATCCAATGGTGAAGAGAACTTAGAGAAGCTCGAAC
TGGAAATCGCGAAACGCCGAACACAAATTGGAAACATCGAGCGTCAATGG
CAAGCTCACAAATCCGAATTGACCCAGGAAATTCAATCGATATCTGATCA
AAAACGCCAAAAACAAACCCGAACGAGTAAGCTCGAATTCCAATTGGCTG
ACGTTAAACAACAAATGGAATCACTGGAAAAAAACTTCCGAGAAAAAACC
TCAGAAATTAAATCTCTCGATGAGAAAGTTAAACAGATTATCAAGGCAAA
CGATCAACAAAACAAGCACCAAAACCGGAACGATTTCACGAAGCGAATCC
TCGAGTTAACGGAAAATAAAAAGAAACAAAAGGAAGAAATCAAAAAGATT
CTCGTTTCGATTTTTGATTTGCAAAAAGGAATTAATGTGTTGCGAGGAAA
ATTAGACCGATCGTTCATGGAAGCGAGAGATTTCATGTTGGATTGCTCGT
CGAAAAAAGACGAAACCGCCAAGAGAATGCATTCGGCTCTTTTGGGAATT
CATGAGAACTGTTCAGAGCTTGTTAGCGTAATCGAAGAAAAAGGCCGATT
GATTCGGGAGATCCGCGAAATCGACACAAACATTGAAAATGAGAACAAGG
AAGACGTAGAGAAAAATCTGGAGAAAATTACCGCAGACTATAACGAGGCT
AAACAAAATTGTGAGAGTTTGAAAAAGTTGCTGAAGGATTACAAACGAAA
TCAGCAAGCGGCCCAATGAAAATTTTGCAACTGAATTTATTGATTATTTT
TACGATTTACCAAACGCAAATCTTACTCCGTCGGATTTTTCTTTACACAA
TTCTAATCATTAATTAATCACTTTTTTATTGTAAATAAAAGTTAATTTTA
AATTAAATTAAACATGAG
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protein sequence of SMED30008044-orf-1

>SMED30008044-orf-1 ID=SMED30008044-orf-1|Name=SMED30008044-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=583bp
MDEADKILIESLISMGLEITDRELSLENFSPDILINATGLCLEYIFESKS
EPQSFPKSCPVNIGSRYKVGQTLSEAIKSLGYKDSVGYQAFLYPNIKDTR
KIISFLIETLPKETGPSVIDRLNESNDITQIIKNTFSENWMSPWLPHYCR
IQSVPFSQYSAKSLLIPFKSDRKPSLNDWFNSFPTIDKQVDRFDEFLFLA
INYDLKTRICENINPDNLTKIIKEMNSTKSEQIINERLNQSKPEVRKRTK
FIEKKSENVDDIEKTIEEAENEYEITEKRFDEIVTIYNTLLDKFDKLNEK
FNKLSLSDKQLDVELESEKAKSITRRKIALILSNGEENLEKLELEIAKRR
TQIGNIERQWQAHKSELTQEIQSISDQKRQKQTRTSKLEFQLADVKQQME
SLEKNFREKTSEIKSLDEKVKQIIKANDQQNKHQNRNDFTKRILELTENK
KKQKEEIKKILVSIFDLQKGINVLRGKLDRSFMEARDFMLDCSSKKDETA
KRMHSALLGIHENCSELVSVIEEKGRLIREIREIDTNIENENKEDVEKNL
EKITADYNEAKQNCESLKKLLKDYKRNQQAAQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR008530CCDC22
Vocabulary: molecular function
TermDefinition
GO:0003674molecular_function
Vocabulary: cellular component
TermDefinition
GO:0005575cellular_component
Vocabulary: biological process
TermDefinition
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 253..287
NoneNo IPR availableCOILSCoilCoilcoord: 333..360
NoneNo IPR availableCOILSCoilCoilcoord: 365..457
NoneNo IPR availableCOILSCoilCoilcoord: 525..578
IPR008530Coiled-coil domain-containing protein 22PFAMPF05667DUF812coord: 218..544
e-value: 1.2E-39
score: 136.8
coord: 2..173
e-value: 2.2E-41
score: 142.5
IPR008530Coiled-coil domain-containing protein 22PANTHERPTHR15668JM1 PROTEINcoord: 2..572