slc30a-2

Overview
Nameslc30a-2 (AKN21622.1)
Smed IDSMED30008023
Length (bp)1293
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of slc30a-2 (SMED30008023) t-SNE clustered cells

Violin plots show distribution of expression levels for slc30a-2 (SMED30008023) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc30a-2 (SMED30008023) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc30a-2 (SMED30008023) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008023

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cephalic gangliaSMED30008023SMESG000008561.1 dd_Smed_v4_10605_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30008023SMESG000008561.1 dd_Smed_v4_10605_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of slc30a-2 vs. Ensembl Human
Match: SLC30A8 (solute carrier family 30 member 8 [Source:HGNC Symbol;Acc:HGNC:20303])

HSP 1 Score: 50.8322 bits (120), Expect = 2.512e-6
Identity = 33/123 (26.83%), Postives = 60/123 (48.78%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIF-KDLKITNCVIQTEKINNEENDALECQMHCQ 1094
            DP+ +   +I+++ + I  L +  I +ME  P  L N S +  LI +VDGV S H  H++S +   +I + H+  +      + ++   K   K   + +  IQ E   +++ D L C+  C 
Sbjct:  199 DPICTFIFSILVLASTITILKDFSILLMEGVPKSL-NYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCEDPCD 320
[Close]
BLAST of slc30a-2 vs. Ensembl Human
Match: SLC30A8 (solute carrier family 30 member 8 [Source:HGNC Symbol;Acc:HGNC:20303])

HSP 1 Score: 50.8322 bits (120), Expect = 2.512e-6
Identity = 33/123 (26.83%), Postives = 60/123 (48.78%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIF-KDLKITNCVIQTEKINNEENDALECQMHCQ 1094
            DP+ +   +I+++ + I  L +  I +ME  P  L N S +  LI +VDGV S H  H++S +   +I + H+  +      + ++   K   K   + +  IQ E   +++ D L C+  C 
Sbjct:  199 DPICTFIFSILVLASTITILKDFSILLMEGVPKSL-NYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCEDPCD 320
[Close]
BLAST of slc30a-2 vs. Ensembl Human
Match: SLC30A8 (solute carrier family 30 member 8 [Source:HGNC Symbol;Acc:HGNC:20303])

HSP 1 Score: 50.8322 bits (120), Expect = 2.512e-6
Identity = 33/123 (26.83%), Postives = 60/123 (48.78%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIF-KDLKITNCVIQTEKINNEENDALECQMHCQ 1094
            DP+ +   +I+++ + I  L +  I +ME  P  L N S +  LI +VDGV S H  H++S +   +I + H+  +      + ++   K   K   + +  IQ E   +++ D L C+  C 
Sbjct:  199 DPICTFIFSILVLASTITILKDFSILLMEGVPKSL-NYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCEDPCD 320
[Close]
BLAST of slc30a-2 vs. Ensembl Human
Match: SLC30A10 (solute carrier family 30 member 10 [Source:HGNC Symbol;Acc:HGNC:25355])

HSP 1 Score: 51.2174 bits (121), Expect = 2.560e-6
Identity = 37/137 (27.01%), Postives = 66/137 (48.18%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEEN-DALECQMHCQTS--SKNCFPRKCC 1130
            DP  ++ M +I+IL+  FPL      ++        N   + + +++V G+ S H  H++   +G IIAT+H+   K+  +  A     +IF    I N  IQ E ++ +E  +  +  + C +   SK C  + CC
Sbjct:  280 DPSLTVLM-VIIILSSAFPLIKETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDRGYQDASTKIREIFHHAGIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKGCAKQLCC 415
[Close]
BLAST of slc30a-2 vs. Ensembl Human
Match: SLC30A8 (solute carrier family 30 member 8 [Source:HGNC Symbol;Acc:HGNC:20303])

HSP 1 Score: 50.447 bits (119), Expect = 3.846e-6
Identity = 33/123 (26.83%), Postives = 60/123 (48.78%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIF-KDLKITNCVIQTEKINNEENDALECQMHCQ 1094
            DP+ +   +I+++ + I  L +  I +ME  P  L N S +  LI +VDGV S H  H++S +   +I + H+  +      + ++   K   K   + +  IQ E   +++ D L C+  C 
Sbjct:  248 DPICTFIFSILVLASTITILKDFSILLMEGVPKSL-NYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCEDPCD 369
[Close]
BLAST of slc30a-2 vs. Ensembl Fly
Match: ZnT63C (gene:FBgn0035432 transcript:FBtr0073054)

HSP 1 Score: 59.6918 bits (143), Expect = 2.543e-9
Identity = 43/162 (26.54%), Postives = 77/162 (47.53%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPL-SNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSK-EEHFPLAQK-------------SCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI*NSLITST 1169
            DP  SI + ++LIL  ++PL   + + +++  PT++  D+    L+  VDGV + H FH++  +   IIA+ H+ C    E+  +A+K             + +  F +++  N    T  IN   +D   C + C T+ + C    CC   +  N L + T
Sbjct:  233 DPALSIVL-VVLILHSVWPLLRESALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFSEIEGCNMSDGTSSINISGSDC--CALDCPTTEEGCVKATCCQNNNKLNQLPSPT 391
[Close]
BLAST of slc30a-2 vs. Ensembl Fly
Match: ZnT63C (gene:FBgn0035432 transcript:FBtr0330104)

HSP 1 Score: 59.6918 bits (143), Expect = 2.543e-9
Identity = 43/162 (26.54%), Postives = 77/162 (47.53%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPL-SNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSK-EEHFPLAQK-------------SCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI*NSLITST 1169
            DP  SI + ++LIL  ++PL   + + +++  PT++  D+    L+  VDGV + H FH++  +   IIA+ H+ C    E+  +A+K             + +  F +++  N    T  IN   +D   C + C T+ + C    CC   +  N L + T
Sbjct:  233 DPALSIVL-VVLILHSVWPLLRESALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFSEIEGCNMSDGTSSINISGSDC--CALDCPTTEEGCVKATCCQNNNKLNQLPSPT 391
[Close]
BLAST of slc30a-2 vs. Ensembl Fly
Match: ZnT63C (gene:FBgn0035432 transcript:FBtr0073056)

HSP 1 Score: 59.6918 bits (143), Expect = 2.543e-9
Identity = 43/162 (26.54%), Postives = 77/162 (47.53%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPL-SNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSK-EEHFPLAQK-------------SCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI*NSLITST 1169
            DP  SI + ++LIL  ++PL   + + +++  PT++  D+    L+  VDGV + H FH++  +   IIA+ H+ C    E+  +A+K             + +  F +++  N    T  IN   +D   C + C T+ + C    CC   +  N L + T
Sbjct:  233 DPALSIVL-VVLILHSVWPLLRESALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFSEIEGCNMSDGTSSINISGSDC--CALDCPTTEEGCVKATCCQNNNKLNQLPSPT 391
[Close]
BLAST of slc30a-2 vs. Ensembl Fly
Match: ZnT63C (gene:FBgn0035432 transcript:FBtr0073058)

HSP 1 Score: 59.6918 bits (143), Expect = 2.543e-9
Identity = 43/162 (26.54%), Postives = 77/162 (47.53%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPL-SNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSK-EEHFPLAQK-------------SCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI*NSLITST 1169
            DP  SI + ++LIL  ++PL   + + +++  PT++  D+    L+  VDGV + H FH++  +   IIA+ H+ C    E+  +A+K             + +  F +++  N    T  IN   +D   C + C T+ + C    CC   +  N L + T
Sbjct:  233 DPALSIVL-VVLILHSVWPLLRESALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFSEIEGCNMSDGTSSINISGSDC--CALDCPTTEEGCVKATCCQNNNKLNQLPSPT 391
[Close]
BLAST of slc30a-2 vs. Ensembl Fly
Match: ZnT63C (gene:FBgn0035432 transcript:FBtr0073057)

HSP 1 Score: 59.6918 bits (143), Expect = 2.543e-9
Identity = 43/162 (26.54%), Postives = 77/162 (47.53%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPL-SNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSK-EEHFPLAQK-------------SCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI*NSLITST 1169
            DP  SI + ++LIL  ++PL   + + +++  PT++  D+    L+  VDGV + H FH++  +   IIA+ H+ C    E+  +A+K             + +  F +++  N    T  IN   +D   C + C T+ + C    CC   +  N L + T
Sbjct:  233 DPALSIVL-VVLILHSVWPLLRESALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFSEIEGCNMSDGTSSINISGSDC--CALDCPTTEEGCVKATCCQNNNKLNQLPSPT 391
[Close]
BLAST of slc30a-2 vs. Ensembl Zebrafish
Match: slc30a1a (solute carrier family 30 member 1a [Source:ZFIN;Acc:ZDB-GENE-040426-1840])

HSP 1 Score: 51.6026 bits (122), Expect = 1.217e-6
Identity = 37/139 (26.62%), Postives = 62/139 (44.60%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKIN-NEENDALECQMHCQTSSKNCFPRKCCMIKD 1142
            DP   I M  IL+ T    L  + + +++  P  + +   +   +  ++GV + H  H++  +   IIAT H+ C     +    K  +  F D  I    IQ E +  N E+ A  C++ C+T    C P+ CC   D
Sbjct:  307 DPTLCIIMVCILLYTTYPLLKESALILLQTVPKQI-DMHQLNARLRDLEGVLAVHELHIWQLAGSRIIATAHIKCHDPTSYMDVAKRIKDFFHDEGIHATTIQPEFVTVNSESRASLCELSCRT---QCAPKLCCGAVD 441
[Close]
BLAST of slc30a-2 vs. Ensembl Zebrafish
Match: slc30a1b (solute carrier family 30 member 1b [Source:ZFIN;Acc:ZDB-GENE-070424-43])

HSP 1 Score: 49.2914 bits (116), Expect = 6.827e-6
Identity = 33/135 (24.44%), Postives = 62/135 (45.93%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTE-KINNEENDALECQMHCQTSSKNCFPRKCC 1130
            DP   + M  IL+ T    L  + + +++  P  + +   +   + S+DGV + H  H++  +   IIAT H+ C+    +    K  + +F D  I    +Q E    +E     +C++ C++    C P+ CC
Sbjct:  300 DPTLCLIMVCILLYTTFPLLKESALILLQTVPEQI-DMPKLKGKLKSLDGVLAVHDLHIWQLAGARIIATAHIKCTDPALYMDIAKRIKDVFHDEGIHATTVQPEFSAFSEGFGDPQCELSCRS---QCKPKLCC 430
[Close]
BLAST of slc30a-2 vs. Ensembl Xenopus
Match: cib3 (calcium and integrin binding family member 3 [Source:Xenbase;Acc:XB-GENE-5787572])

HSP 1 Score: 53.5286 bits (127), Expect = 4.587e-7
Identity = 36/135 (26.67%), Postives = 64/135 (47.41%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALE-CQMHCQTSSKNCFPRKCC 1130
            DP   + M  IL+ T    L  + + +++  P  + + SS+   + ++DGV++ H  H++  +   IIAT H+ C     +    K  +  F D  I    IQ E  + E    +  C++ C+T    C P++CC
Sbjct:  309 DPSLCVIMVCILLYTTYPLLKESALILLQTVPKQI-DISSLKQKLKNLDGVEAVHELHVWQLAESRIIATAHIKCHDPTAYMDVAKRIKDFFHDEGIHATTIQPEFSSVESGSRISLCELSCRT---QCAPKQCC 439
[Close]
BLAST of slc30a-2 vs. Ensembl Mouse
Match: Slc30a10 (solute carrier family 30, member 10 [Source:MGI Symbol;Acc:MGI:2685058])

HSP 1 Score: 52.373 bits (124), Expect = 7.038e-7
Identity = 42/142 (29.58%), Postives = 70/142 (49.30%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPL-SNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALE-------CQMHCQTSSKNCFPRKCC 1130
            DP  ++ M +I+IL+  FPL     + +++  P  + N   + + +++V G+ S H  H++   +G IIAT+H+   K   +  A +   +IF    I N  IQ E ++ +E  ALE       C   C T S  C  + CC
Sbjct:  272 DPSLTVVM-VIIILSSAFPLIKETAVILLQMVPKGV-NMEELMSQLSTVPGISSVHEVHIWELISGKIIATLHIKHQKGTEYQDASRKIREIFHHAGIHNVTIQFETLDLKE--ALEQKDFLLTCSAPCITQS--CAKKLCC 407
[Close]
BLAST of slc30a-2 vs. Ensembl Mouse
Match: Slc30a1 (solute carrier family 30 (zinc transporter), member 1 [Source:MGI Symbol;Acc:MGI:1345281])

HSP 1 Score: 50.0618 bits (118), Expect = 4.235e-6
Identity = 34/138 (24.64%), Postives = 63/138 (45.65%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKIN-NEENDALECQMHCQTSSKNCFPRKCCMIK 1139
            DP   I M  IL+ T    L  + + +++  P  + +   +   +  VDGV+  H  H++  +   IIAT H+ C     +    K+ + +F +  I    IQ E  +   ++  L C++ C+T    C  ++CC  +
Sbjct:  312 DPTLCIIMVCILLYTTYPLLKESALILLQTVPKQI-DIKHLVKELRDVDGVEEVHELHVWQLAGSRIIATAHIKCEDPASYMQVAKTIKDVFHNHGIHATTIQPEFASVGSKSSVLPCELACRT---QCALKQCCGTR 445
[Close]
BLAST of slc30a-2 vs. Ensembl Mouse
Match: Slc30a1 (solute carrier family 30 (zinc transporter), member 1 [Source:MGI Symbol;Acc:MGI:1345281])

HSP 1 Score: 50.0618 bits (118), Expect = 4.235e-6
Identity = 34/138 (24.64%), Postives = 63/138 (45.65%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKIN-NEENDALECQMHCQTSSKNCFPRKCCMIK 1139
            DP   I M  IL+ T    L  + + +++  P  + +   +   +  VDGV+  H  H++  +   IIAT H+ C     +    K+ + +F +  I    IQ E  +   ++  L C++ C+T    C  ++CC  +
Sbjct:  312 DPTLCIIMVCILLYTTYPLLKESALILLQTVPKQI-DIKHLVKELRDVDGVEEVHELHVWQLAGSRIIATAHIKCEDPASYMQVAKTIKDVFHNHGIHATTIQPEFASVGSKSSVLPCELACRT---QCALKQCCGTR 445
[Close]
BLAST of slc30a-2 vs. UniProt/SwissProt
Match: sp|Q3UVU3|ZNT10_MOUSE (Zinc transporter 10 OS=Mus musculus OX=10090 GN=Slc30a10 PE=1 SV=1)

HSP 1 Score: 52.373 bits (124), Expect = 4.923e-6
Identity = 42/142 (29.58%), Postives = 70/142 (49.30%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPL-SNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALE-------CQMHCQTSSKNCFPRKCC 1130
            DP  ++ M +I+IL+  FPL     + +++  P  + N   + + +++V G+ S H  H++   +G IIAT+H+   K   +  A +   +IF    I N  IQ E ++ +E  ALE       C   C T S  C  + CC
Sbjct:  272 DPSLTVVM-VIIILSSAFPLIKETAVILLQMVPKGV-NMEELMSQLSTVPGISSVHEVHIWELISGKIIATLHIKHQKGTEYQDASRKIREIFHHAGIHNVTIQFETLDLKE--ALEQKDFLLTCSAPCITQS--CAKKLCC 407
[Close]
BLAST of slc30a-2 vs. TrEMBL
Match: A0A0H3YFH9 (Slc30a-2 OS=Schmidtea mediterranea OX=79327 GN=slc30a-2 PE=2 SV=1)

HSP 1 Score: 701.434 bits (1809), Expect = 0.000e+0
Identity = 361/361 (100.00%), Postives = 361/361 (100.00%), Query Frame = 3 
Query:   63 FCYIPCLVIEILFIPSSIYVCFTQKCVLTFINLINVLNVFVGNIILIKTMCILQNKKLGVPRLHTLIELINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIIISVYGLFQXXXXXXXXXXXXXDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI 1145
            FCYIPCLVIEILFIPSSIYVCFTQKCVLTFINLINVLNVFVGNIILIKTMCILQNKKLGVPRLHTLIELINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIIISVYGLFQINKTINKNILNLIDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI
Sbjct:   10 FCYIPCLVIEILFIPSSIYVCFTQKCVLTFINLINVLNVFVGNIILIKTMCILQNKKLGVPRLHTLIELINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIIISVYGLFQINKTINKNILNLIDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI 370
[Close]
BLAST of slc30a-2 vs. TrEMBL
Match: A0A1Y1K3C1 (Uncharacterized protein OS=Photinus pyralis OX=7054 GN=PPYR_07979 PE=4 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 3.516e-12
Identity = 77/316 (24.37%), Postives = 141/316 (44.62%), Query Frame = 3 
Query:  237 GVPRLHTLIELINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFSSDHS--NSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGT-LHFLCSIIISVYGLFQXX--XXXXXXXXXXXDPVSSITMAIILILTKIFPL-SNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSK-EEHFPLAQKSCEKIFKDLKITNCVIQTEKIN-------NEENDAL--ECQMHCQTSSKN--CFPRKCC 1130
            G  R   L  L+N +      F+  + + + F    E+ DP  L+ +G  G+  N I +    ++ +       +S++  R S   +  + + +T +NE        P ++  +   H +S   S     +M   G  LH L   + SV  +         +    + IDP  S+ + +ILIL  ++PL  ++ + +++  PT++  D+    L+  VDGV + H FH++  +   IIA+ H+ C    E+  +A+K  ++ F +  I +  IQ E I+        EEN+    +C + C  S+ N  C    CC
Sbjct:   71 GWARAEVLGALVNAVFLVALCFSITVEACKRFIETTEIHDPQLLLTVGVIGLIVNLIGLF---LFQEHGG----SSHSHGRLSGSRNRLSQLAVTDDNENDATYPSPPPAVSAKHSMHGHSHGSS---AGQMNMRGVFLHVLSDALGSVIVIISATIFWLTDWKYKDYIDPGLSVIL-VILILRSVWPLLRDSALILLQTVPTHIQIDAIQRRLLTKVDGVLAVHEFHVWQLAGDRIIASAHIRCRNLSEYMRIAEK-VKEFFHNEGIHSTTIQPEFIDYREYPESTEENEQQTEDCILDCPRSTSNDTCILNTCC 374
[Close]
BLAST of slc30a-2 vs. TrEMBL
Match: A0A1I8PAC3 (Uncharacterized protein OS=Stomoxys calcitrans OX=35570 GN=106093336 PE=4 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 6.393e-11
Identity = 78/308 (25.32%), Postives = 132/308 (42.86%), Query Frame = 3 
Query:  237 GVPRLHTLIELINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFSSDHSN--SVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLC----SIIISVYGLFQXXXXXXXXXXXXXDPVSSITMAIILILTKIFPL-SNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSK-EEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMI 1136
            G  R   L  L+N +      F+  I + + F     + +P  L+I+G  G+  N I +   ++Y    +    +    RR  S  +   +V     NE    +K+K K +      H +      P  + M     LH L     SII+ +  L       +      +DP  SI + + LIL  ++PL   + + +++  PT++  D+    L+  VDGV + H FH++  +   IIA+ H+ C    E+  +A+K  ++ F +  I +  IQ E +   E D   C M   TSS N     CC +
Sbjct:   71 GWARAEVLGALVNAVFLVALCFSITIEACKRFIEEETIHEPKLLVIVGALGLLVNVIGLC--LLYEHGGHHGHSHGGGLRRNHSRLTELANVDEGEANEEFAYEKQKEKPVKKSSHGHSHD-----PGAMNM-RGAFLHVLSDALGSIIVVISALV--VWKTDWRYRYYMDPALSIVL-VCLILHSVWPLLRESALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRCHNLSEYMKIAEK-VKEFFHNEGIHSTTIQPEFV---EMDGGGCIMSDGTSSLNMSGSDCCAL 363
[Close]
BLAST of slc30a-2 vs. TrEMBL
Match: R7TA79 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_151660 PE=4 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.387e-10
Identity = 41/134 (30.60%), Postives = 67/134 (50.00%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCC 1130
            DP  S+ M +I++ T I  L  + + +++ APT++        LI+ V+GV + H FH++  +   IIA+ H+ C     +    +  +  F D  I +  IQ E +  EE    +C + C    KNCFP  CC
Sbjct:  241 DPAMSMAMVLIILCTTIPLLKQSAMILLQTAPTHIQVQEIQEKLISKVEGVLAVHEFHVWQLAGNRIIASAHIRCQNLRDYMRIAEEVKMFFHDEGIHSTTIQPEFVEFEEISGRDCVLEC-GPDKNCFPDTCC 373
[Close]
BLAST of slc30a-2 vs. TrEMBL
Match: A0A1B6D2D7 (Uncharacterized protein OS=Clastoptera arizonana OX=38151 GN=g.41833 PE=4 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 2.589e-10
Identity = 76/315 (24.13%), Postives = 132/315 (41.90%), Query Frame = 3 
Query:  237 GVPRLHTLIELINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEI-ITDIIYSQENNFIMFNSYTQRRFSSDHSNSVCITTEN-ETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGT-LHFLCSIIISVYGLFQXXXXXXXXXXXX--XDPVSSITMAIILILTKIFPL-SNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSK-EEHFPLAQKSCEKIFKDLKITNCVIQTE----------KINNEENDALECQMHCQTSSKNCFPRKCC 1130
            G  R   L  L+N +      F+  + + + F    E+ +P  ++I+G  G+  N I + +         +     +++  R +   S       EN ET       PKS   +   H  S         +M   G  LH L   + SV  +   +            +DPV SI M +ILIL  ++PL   + + +++  PT++  D+    L++ VDGV + H FH++  +   IIA+ H+ C    E+  +A+K  ++ F +  I +  IQ E          KI N  ++  +C + C  +   C    CC
Sbjct:   71 GWARAEVLGALVNAVFLVALCFSITVEACKRFIEVEEIHEPKMIVIVGALGLLVNIIGLFLFHDHGGGHGHSHGGITHSHPRLTQLVSVGATDDNENDETFRPPPSNPKSASEKNHSHNAS-------ADQMNMRGVFLHVLADALGSVIVIASASIVWLTEWKYRYYMDPVLSIVM-VILILRSVWPLLQESALILLQTVPTHIQVDAIQRKLLDKVDGVLAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEK-VKEFFHNEGIHSTTIQPEFVEIAEFSEDKIQNSPSE--DCVLDCPKTDTPCALSTCC 374
[Close]
BLAST of slc30a-2 vs. Ensembl Cavefish
Match: slc30a1a (solute carrier family 30 member 1 [Source:NCBI gene;Acc:103024690])

HSP 1 Score: 51.2174 bits (121), Expect = 1.257e-6
Identity = 36/139 (25.90%), Postives = 64/139 (46.04%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKIN-NEENDALECQMHCQTSSKNCFPRKCCMIKD 1142
            DP   + M  IL+ T    L  + + +++  P  + +  S+ + +  ++GV + H  H++  +   IIAT H+ C     +    K  +  F D  I    IQ E +  N E+ A  C++ C+T    C  ++CC   D
Sbjct:  317 DPTLCVIMVCILLYTTYPLLKESALILLQTVPKQI-DMHSLNSRLQELEGVLAVHELHIWQLAGSRIIATAHIKCHDPASYMDVAKRIKAFFHDEGIHATTIQPEFVTVNSESRASLCELSCRT---QCATKQCCGSGD 451
[Close]
BLAST of slc30a-2 vs. Ensembl Yeast
Match: ZRC1 (Vacuolar membrane zinc transporter; transports zinc from cytosol to vacuole for storage; also has role in resistance to zinc shock resulting from sudden influx of zinc into cytoplasm; human ortholog SLC30A10 functions as a Mn transporter and mutations in SLC30A10 cause neurotoxic accumulation of Mn in liver and brain; ZRC1 has a paralog, COT1, that arose from the whole genome duplication [Source:SGD;Acc:S000004856])

HSP 1 Score: 46.595 bits (109), Expect = 4.174e-6
Identity = 66/313 (21.09%), Postives = 130/313 (41.53%), Query Frame = 3 
Query:  237 GVPRLHTLIELINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEII------TDIIYSQENNFI------------MFNSYTQRRFSSDHS--NSVCITTENETIIVKKKKPKSLFMRFF----------KHFYSLYWSYPRVVKMLTCGT-LHFLCSII--ISVYGLFQXXXXXXXXXXXXXDPVSSITMAIILILTKIFPLSNNLITVM-EAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLV--CSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEEND 1067
            G  R   L  LIN +      F+ +I ++Q    P E+Q+P  ++ +G  G+  N + +       +D ++S  +  +              +S++     +D+   +   I++   +  + +  P+S+  R             H +S     P    +   G  LH L   +  I V            +     DP+ S+ + II+  +   PLS     ++ +A P+ +  D  I   I +V GV + H FH+++ +  + IA+IH+   C+ ++ F  + K   KIF    I +  +Q E ++ + N+
Sbjct:   71 GWKRAEILGALINAVFLIALCFSIMIEALQRLIEPQEIQNPRLVLYVGVAGLISNVVGLFLFHDHGSDSLHSHSHGSVESGNNDLDIESNATHSHSHASLPNDNLAIDEDAISSPGPSGQIGEVLPQSVVNRLSNESQPLLNHDDHDHSHESKKPGHRSLNMHGVFLHVLGDALGNIGVIAAALFIWKTEYSWRYYSDPIVSLIITIII-FSSALPLSRRASRILLQATPSTISADQ-IQREILAVPGVIAVHDFHVWNLTESIYIASIHVQIDCAPDK-FMSSAKLIRKIFHQHGIHSATVQPEFVSGDVNE 380
[Close]
BLAST of slc30a-2 vs. Ensembl Medaka
Match: slc30a1a (solute carrier family 30 member 1 [Source:NCBI gene;Acc:101156788])

HSP 1 Score: 55.8398 bits (133), Expect = 4.761e-8
Identity = 38/135 (28.15%), Postives = 61/135 (45.19%), Query Frame = 3 
Query:  729 DPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKIN-NEENDALECQMHCQTSSKNCFPRKCC 1130
            DP   I M  IL+ T    L  + + +++  P  + N   +   + S+DGV + H  H++  +   IIAT H+ C     +    K  +  F D  I    IQ E +  N E    +C++ C+T    C P+ CC
Sbjct:  296 DPTLCIIMVGILLYTTYPLLKESALILLQTVPKQI-NMHRLNERLLSLDGVLAIHDLHIWQLAGSRIIATAHIKCHDPTSYMDVAKRIKDFFHDEGIHATTIQPEFVTFNSETQGSQCELSCRT---QCAPKLCC 426
[Close]
BLAST of slc30a-2 vs. Planmine SMEST
Match: SMESG000008561.1 (SMESG000008561.1)

HSP 1 Score: 694.115 bits (1790), Expect = 0.000e+0
Identity = 357/361 (98.89%), Postives = 359/361 (99.45%), Query Frame = 3 
Query:   63 FCYIPCLVIEILFIPSSIYVCFTQKCVLTFINLINVLNVFVGNIILIKTMCILQNKKLGVPRLHTLIELINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIIISVYGLFQXXXXXXXXXXXXXDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI 1145
            F YIPCLVIEILFIPSSIYVCFTQKCVLTFINLINVLNVFVGNIILIKTMCILQNKKLGVPRLHTLIE+INYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIII+VYGLFQINKTINKNILNLIDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGM IATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI
Sbjct:   10 FFYIPCLVIEILFIPSSIYVCFTQKCVLTFINLINVLNVFVGNIILIKTMCILQNKKLGVPRLHTLIEIINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIIIAVYGLFQINKTINKNILNLIDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMFIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI 370
[Close]
BLAST of slc30a-2 vs. Planmine SMEST
Match: SMESG000008561.1 (SMESG000008561.1)

HSP 1 Score: 605.134 bits (1559), Expect = 0.000e+0
Identity = 309/312 (99.04%), Postives = 311/312 (99.68%), Query Frame = 3 
Query:  210 MCILQNKKLGVPRLHTLIELINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIIISVYGLFQXXXXXXXXXXXXXDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI 1145
            MCILQNKKLGVPRLHTLIE+INYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIII+VYGLFQINKTINKNILNLIDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGM IATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI
Sbjct:    1 MCILQNKKLGVPRLHTLIEIINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIIIAVYGLFQINKTINKNILNLIDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMFIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI 312
[Close]
BLAST of slc30a-2 vs. Planmine SMEST
Match: SMESG000008561.1 (SMESG000008561.1)

HSP 1 Score: 442.195 bits (1136), Expect = 2.482e-156
Identity = 230/238 (96.64%), Postives = 233/238 (97.90%), Query Frame = 3 
Query:  432 SQENNFIMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIIISVYGLFQXXXXXXXXXXXXXDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI 1145
            S  ++  MFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIII+VYGLFQINKTINKNILNLIDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGM IATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI
Sbjct:   12 SSHHDNSMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIIIAVYGLFQINKTINKNILNLIDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMFIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQMHCQTSSKNCFPRKCCMIKDI 249
[Close]
BLAST of slc30a-2 vs. Planmine SMEST
Match: SMESG000069698.1 (SMESG000069698.1)

HSP 1 Score: 67.781 bits (164), Expect = 3.519e-12
Identity = 79/356 (22.19%), Postives = 148/356 (41.57%), Query Frame = 3 
Query:  147 TFINLINVLNVFVGNIILIKTMCILQNK--KLGVPRLHTLIELINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEI----------ITDIIYSQENNFIMFNSYTQRRFSSDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLH----FLCSIIISVYGLF-----QXXXXXXXXXXXXXDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALE--CQMHCQTSSKNCFPRKCCMIKDI 1145
            +F  L +V+++ +G I+ IK   + ++     G  R      LIN +      FT  + +IQ FF P +V DP  ++ +G  G+  NFI +          I +I   +  N++               + +      + +I+    P  + +       S+          +T   LH    F+ S+I+ +  L         K+ +      +DP  SI M II++L  I  +    + ++++ P  + N   ++N I  +  V S H  H++     +II T+H+     + F L   + +K+  D  I    +Q E   + E++  +  C++ C  SS  C P  CC  ++I
Sbjct:   42 SFHMLSDVVSIIIG-IVAIKVSKLPKSGLNTFGWQRAEVFGSLINCISLIALSFTVFVSAIQRFFEPEKVSDPLIMLFVGTGGLFINFIGLVLLSSTHSHKIKEIENPKLPNYVKSTDSEGEDTLIPTESQISEIENKDDLIMGPPIPGQVRLSTINEDQSMN---------MTAVFLHVFADFVGSVIVCISALLLLYGPGDIKSSSGLYKLYVDPSLSIIMVIIIVLPTISLVKQASLVLLQSVPQEI-NIKHLSNDIRQIKNVISMHDLHIWRLRPKVIIGTVHVKVRSIDDFNLTALAVKKLLHDYNIHCTTVQPEFTQSSEDNKSDDKCELTCDPSSL-CTPNICCPQEEI 385
[Close]
BLAST of slc30a-2 vs. Planmine SMEST
Match: SMESG000075723.1 (SMESG000075723.1)

HSP 1 Score: 65.0846 bits (157), Expect = 3.087e-11
Identity = 62/284 (21.83%), Postives = 127/284 (44.72%), Query Frame = 3 
Query:  237 GVPRLHTLIELINYLVFYTFLFTCIIHSIQEFFHPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENN------FIMFNSYTQRRFSSDHSNSVC--ITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTCGTLHFLCSIIISVYGLFQXX----XXXXXXXXXXXDPVSSITMAIILILTKIFPLSNNLITVMEAAPTYLWNDSSITNL---INSVDGVKSCHCFHLYSDSNGMIIATIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTE 1043
            G  R   +  L+N ++  T  FT +I SIQ F  P E++ P  +  +G  G+  N I +I  I+ +   +       I+     +     D   S    +   +  I++K  + ++      K    +     R V +     L    +++IS   L+Q+              ++DP+ S+ M ++++++ +  L  + + ++++ P     D SI  L   + +++G++  H  H++   + +II T+H+ CS  E++  A K  +K+F + +I    IQ E
Sbjct:   59 GWQRAEVVGSLVNTVMLTTLTFTILIKSIQRFIQPEEIEKPHIIFYVGLGGLLVNIIGLI--ILRNHHGHSHGPETAILLKEEEEELVDDDIPESPVPNLVDGDVKIVIKDNEGENHGHSQKKGASHMNM---RAVYLHVLADLFGSIAVVISAIVLWQVPNFQNPPKTDYWKLMVDPLISVLMVVLILISTVPLLKQSALILLQSVP----KDVSIKELKDRMENIEGIEKVHDLHVWLLQSDVIIGTVHIRCSN-ENYVTASKKVKKLFHEFRIHCTTIQAE 332
The following BLAST results are available for this feature:
BLAST of slc30a-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SLC30A82.512e-626.83solute carrier family 30 member 8 [Source:HGNC Sym... [more]
SLC30A82.512e-626.83solute carrier family 30 member 8 [Source:HGNC Sym... [more]
SLC30A82.512e-626.83solute carrier family 30 member 8 [Source:HGNC Sym... [more]
SLC30A102.560e-627.01solute carrier family 30 member 10 [Source:HGNC Sy... [more]
SLC30A83.846e-626.83solute carrier family 30 member 8 [Source:HGNC Sym... [more]
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BLAST of slc30a-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of slc30a-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ZnT63C2.543e-926.54gene:FBgn0035432 transcript:FBtr0073054[more]
ZnT63C2.543e-926.54gene:FBgn0035432 transcript:FBtr0330104[more]
ZnT63C2.543e-926.54gene:FBgn0035432 transcript:FBtr0073056[more]
ZnT63C2.543e-926.54gene:FBgn0035432 transcript:FBtr0073058[more]
ZnT63C2.543e-926.54gene:FBgn0035432 transcript:FBtr0073057[more]
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BLAST of slc30a-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
slc30a1a1.217e-626.62solute carrier family 30 member 1a [Source:ZFIN;Ac... [more]
slc30a1b6.827e-624.44solute carrier family 30 member 1b [Source:ZFIN;Ac... [more]
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BLAST of slc30a-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cib34.587e-726.67calcium and integrin binding family member 3 [Sour... [more]
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BLAST of slc30a-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Slc30a107.038e-729.58solute carrier family 30, member 10 [Source:MGI Sy... [more]
Slc30a14.235e-624.64solute carrier family 30 (zinc transporter), membe... [more]
Slc30a14.235e-624.64solute carrier family 30 (zinc transporter), membe... [more]
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BLAST of slc30a-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 1
Match NameE-valueIdentityDescription
sp|Q3UVU3|ZNT10_MOUSE4.923e-629.58Zinc transporter 10 OS=Mus musculus OX=10090 GN=Sl... [more]
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BLAST of slc30a-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YFH90.000e+0100.00Slc30a-2 OS=Schmidtea mediterranea OX=79327 GN=slc... [more]
A0A1Y1K3C13.516e-1224.37Uncharacterized protein OS=Photinus pyralis OX=705... [more]
A0A1I8PAC36.393e-1125.32Uncharacterized protein OS=Stomoxys calcitrans OX=... [more]
R7TA791.387e-1030.60Uncharacterized protein OS=Capitella teleta OX=283... [more]
A0A1B6D2D72.589e-1024.13Uncharacterized protein OS=Clastoptera arizonana O... [more]
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BLAST of slc30a-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
slc30a1a1.257e-625.90solute carrier family 30 member 1 [Source:NCBI gen... [more]
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BLAST of slc30a-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of slc30a-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
ZRC14.174e-621.09Vacuolar membrane zinc transporter; transports zin... [more]
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BLAST of slc30a-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of slc30a-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
slc30a1a4.761e-828.15solute carrier family 30 member 1 [Source:NCBI gen... [more]
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BLAST of slc30a-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000008561.10.000e+098.89SMESG000008561.1[more]
SMESG000008561.10.000e+099.04SMESG000008561.1[more]
SMESG000008561.12.482e-15696.64SMESG000008561.1[more]
SMESG000069698.13.519e-1222.19SMESG000069698.1[more]
SMESG000075723.13.087e-1121.83SMESG000075723.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30008023
GenBankAKN21622.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008023 ID=SMED30008023|Name=slc30a-2|organism=Schmidtea mediterranea sexual|type=transcript|length=1293bp
GTTAATTAATTTTTTTGAAATTATAAATTAAAATCATGAAAGATAAATTA
CGAAGAAAATTGTTTTGTTATATTCCATGTCTTGTTATTGAGATTCTATT
TATTCCATCATCTATTTATGTGTGTTTCACTCAGAAATGTGTTTTAACCT
TTATAAATCTTATCAATGTCTTAAATGTTTTCGTTGGAAATATTATTCTA
ATAAAAACTATGTGCATTTTACAAAACAAGAAATTAGGAGTACCGCGTTT
GCATACTTTAATTGAGTTAATTAACTATTTGGTTTTTTATACATTTCTTT
TCACTTGTATTATTCACTCAATTCAAGAATTTTTTCATCCAAATGAAGTT
CAAGATCCTGGTAGATTGATTATAATCGGATTTTTTGGAATGGCCTGCAA
TTTTATAGAAATTATTACAGATATTATTTATTCTCAAGAAAATAATTTTA
TTATGTTCAATTCTTATACGCAACGGAGATTTTCTTCAGATCATTCTAAT
TCCGTGTGTATAACAACTGAAAATGAAACTATAATTGTTAAAAAGAAGAA
ACCCAAATCATTGTTTATGAGATTTTTCAAACATTTTTATTCCTTATATT
GGTCATATCCAAGAGTTGTTAAAATGCTAACATGCGGTACGTTGCATTTT
CTCTGCTCAATTATAATTTCTGTTTACGGGCTTTTCCAAATTAACAAAAC
TATTAACAAAAATATTCTAAATCTAATTGATCCAGTTTCCAGTATAACCA
TGGCAATCATTCTTATTTTGACCAAAATATTTCCATTGTCAAACAATTTA
ATAACGGTCATGGAAGCGGCGCCAACGTATTTATGGAATGATTCATCCAT
TACAAATTTGATAAATTCGGTAGATGGAGTTAAAAGCTGTCATTGTTTTC
ACCTTTATTCAGACTCGAATGGGATGATCATCGCAACAATACATTTAGTT
TGTTCCAAAGAAGAACACTTTCCATTGGCCCAGAAGTCCTGTGAGAAGAT
ATTCAAAGATTTGAAAATAACCAATTGCGTCATTCAAACAGAAAAGATAA
ACAATGAAGAGAATGATGCACTGGAATGTCAAATGCATTGTCAAACATCG
TCGAAAAATTGTTTTCCTCGAAAATGTTGTATGATAAAAGACATTTGAAA
TTCATTGATAACCTCGACGGTGGGGGTAAGAAGAGAATAGATTAACTATT
TTGATAATACAGTTAAAATGTTATTTTTTATGTTGATGTAATAAATTTTG
TAAATTTTCGTAATAAAGGGATTGTATATATTTTCAAAAAAAA
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protein sequence of SMED30008023-orf-1

>SMED30008023-orf-1 ID=SMED30008023-orf-1|Name=SMED30008023-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=371bp
MKDKLRRKLFCYIPCLVIEILFIPSSIYVCFTQKCVLTFINLINVLNVFV
GNIILIKTMCILQNKKLGVPRLHTLIELINYLVFYTFLFTCIIHSIQEFF
HPNEVQDPGRLIIIGFFGMACNFIEIITDIIYSQENNFIMFNSYTQRRFS
SDHSNSVCITTENETIIVKKKKPKSLFMRFFKHFYSLYWSYPRVVKMLTC
GTLHFLCSIIISVYGLFQINKTINKNILNLIDPVSSITMAIILILTKIFP
LSNNLITVMEAAPTYLWNDSSITNLINSVDGVKSCHCFHLYSDSNGMIIA
TIHLVCSKEEHFPLAQKSCEKIFKDLKITNCVIQTEKINNEENDALECQM
HCQTSSKNCFPRKCCMIKDI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR027469Cation_efflux_TMD_sf
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePANTHERPTHR45820FAMILY NOT NAMEDcoord: 68..127
coord: 206..367
NoneNo IPR availableTMHMMTMhelixcoord: 234..256
NoneNo IPR availableTMHMMTMhelixcoord: 9..31
NoneNo IPR availableTMHMMTMhelixcoord: 77..96
NoneNo IPR availableTMHMMTMhelixcoord: 197..219
NoneNo IPR availableTMHMMTMhelixcoord: 36..56
NoneNo IPR availableTMHMMTMhelixcoord: 111..133
IPR027469Cation efflux transmembrane domain superfamilySUPERFAMILYSSF161111Cation efflux protein transmembrane domain-likecoord: 65..133