Discoidin domain-containing receptor 2

Query: 1687 NNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSH--RSIPMYGPAR-----VSIQGPLRNSKLQSITTVNDPEIM----------FSLGSLFNDL-SYANVALEN-----LKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDS--VVVSEHTALDDAYSYLQNFTLKELSDLH-----YETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFL 2997
            NN   + S+    S YD + P+  +        EPS   R +P + P         +  P++ S  + +    + +I+          +S+ ++  DL S  +VA+E      L + + +    FG +H+ E        +E  +KF+  ++  L  S    +             + ++K+L  +  +  +N+F KEIK +  L     P I+      + D    +++E         Y++N  L +    H       +  + +S +NL +MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE  T C++QPY +L++EQVI N+        R   LP P          +  C   +   RPSF EI + L
Sbjct:  456 NNRSSSPSEQGSNSTYDRIFPLRPD------YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCE--------VEGMEKFKDKDF-ALDVSANQPV-------------LVAVKMLRADANKNARNDFLKEIKIMSRLKD---PNIIHLLAVCITDDPLCMITE---------YMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV-GKNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849          

Query:  121 TNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR--------MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKND-------QLVGW-DKQKTNQ-VQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRV-LQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSD 1101
             N   C   L  +  ++PD   T SS + E    K+ R  +   + AWCP   +  D  ++FL IDL  ++ + ++ T+G     HG   A  Y I Y R+  + W  +R+R  ++ + GN +      + L+P I+AR+V+  P  +    +C+ +++YGC ++  ++ Y         +  GS + L D  YDG    S ++ GLG+L      L  D F   ++         VGW ++  TN  ++I F F + +NF+ + +  +   +K VK+F  +Q  F  +   ++   +     +D+      F +VP  L + +   +K    F   W++   I FQSD
Sbjct:   25 VNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDG-TRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYS-MTEGLGQLTDGVSGL--DDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVP--LHHRMASAIKCQYHFADTWMMFSEITFQSD 367          

Query: 1687 NNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSH--RSIPMYGPAR-----VSIQGPLRNSKLQSITTVNDPEIM----------FSLGSLFNDL-SYANVALEN-----LKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDS--VVVSEHTALDDAYSYLQNFTLKELSDLH-----YETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFL 2997
            NN   + S+    S YD + P+  +        EPS   R +P + P         +  P++ S  + +    + +I+          +S+ ++  DL S  +VA+E      L + + +    FG +H+ E        +E  +KF+  ++  L  S    +             + ++K+L  +  +  +N+F KEIK +  L     P I+      + D    +++E         Y++N  L +    H       +  + +S +NL +MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE  T C++QPY +L++EQVI N+        R   LP P          +  C   +   RPSF EI + L
Sbjct:  456 NNRSSSPSEQGSNSTYDRIFPLRPD------YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCE--------VEGMEKFKDKDF-ALDVSANQPV-------------LVAVKMLRADANKNARNDFLKEIKIMSRLKD---PNIIHLLAVCITDDPLCMITE---------YMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV-GKNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849          

Query:  121 TNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR--------MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKND-------QLVGW-DKQKTNQ-VQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRV-LQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSD 1101
             N   C   L  +  ++PD   T SS + E    K+ R  +   + AWCP   +  D  ++FL IDL  ++ + ++ T+G     HG   A  Y I Y R+  + W  +R+R  ++ + GN +      + L+P I+AR+V+  P  +    +C+ +++YGC ++  ++ Y         +  GS + L D  YDG    S ++ GLG+L      L  D F   ++         VGW ++  TN  ++I F F + +NF+ + +  +   +K VK+F  +Q  F  +   ++   +     +D+      F +VP  L + +   +K    F   W++   I FQSD
Sbjct:   25 VNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDG-TRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYS-MTEGLGQLTDGVSGL--DDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVP--LHHRMASAIKCQYHFADTWMMFSEITFQSD 367          

Query: 1687 NNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSH--RSIPMYGPAR-----VSIQGPLRNSKLQSITTVNDPEIM----------FSLGSLFNDL-SYANVALEN-----LKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDS--VVVSEHTALDDAYSYLQNFTLKELSDLH-----YETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFL 2997
            NN   + S+    S YD + P+  +        EPS   R +P + P         +  P++ S  + +    + +I+          +S+ ++  DL S  +VA+E      L + + +    FG +H+ E        +E  +KF+  ++  L  S    +             + ++K+L  +  +  +N+F KEIK +  L     P I+      + D    +++E         Y++N  L +    H       +  + +S +NL +MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE  T C++QPY +L++EQVI N+        R   LP P          +  C   +   RPSF EI + L
Sbjct:  456 NNRSSSPSEQGSNSTYDRIFPLRPD------YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCE--------VEGMEKFKDKDF-ALDVSANQPV-------------LVAVKMLRADANKNARNDFLKEIKIMSRLKD---PNIIHLLAVCITDDPLCMITE---------YMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV-GKNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849          

Query:  121 TNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR--------MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKND-------QLVGW-DKQKTNQ-VQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRV-LQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSD 1101
             N   C   L  +  ++PD   T SS + E    K+ R  +   + AWCP   +  D  ++FL IDL  ++ + ++ T+G     HG   A  Y I Y R+  + W  +R+R  ++ + GN +      + L+P I+AR+V+  P  +    +C+ +++YGC ++  ++ Y         +  GS + L D  YDG    S ++ GLG+L      L  D F   ++         VGW ++  TN  ++I F F + +NF+ + +  +   +K VK+F  +Q  F  +   ++   +     +D+      F +VP  L + +   +K    F   W++   I FQSD
Sbjct:   25 VNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDG-TRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYS-MTEGLGQLTDGVSGL--DDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVP--LHHRMASAIKCQYHFADTWMMFSEITFQSD 367          

Query: 1861 LQSITTVNDPEI-MFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYLQNFTLKELS------DLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            LQ +T  N   +     G++ +     +     L++ + +    FG +H+ E   P D +                 SL   +   N+ +  P   + ++K+L  + T+  +N+F KE+K +  L     P I++      ++ PL    +++++    D   +L    L++ +      D     G   IS   L+++A+QIA GM++L  L  VHRDL+ RN L+  ++  IKI+D  ++   ++ DY                                  +    VLPIRWM W+ +L G F+  SDV++FGVT WE+L LCR QP+ +LT+EQVI N+        R   L  P    +   + +  C       RP F ++  FL   ++
Sbjct:  540 LQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLV-----------------SLDFPL---NVRKGHP--LLVAVKILRPDATKNARNDFLKEVKIMSRLKD---PNIIRLLGVCVQDDPL---CMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQG-PTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV-GENFTIKIADFGMSRNLYAGDY--------------------------------YRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDAL 873          

Query:  226 ARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGS--YLN----LTDFNYDG-----DKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTND 1113
            +R  +S  + AWCP   +  K  ++L +DL  ++++ ++ T+G    G     + SY + Y R+    W  ++ R  Q+ I GN+D      + L P ++AR V+ YP A+   ++CL +++YGC +   ++ Y    G   YL+    L D  YDG      +         G + L+    S++         VGW      +  V++ F F + + F  + +  +   +   +L   ++ +F        E   ++ ++          +V V L   V +F++    F   W++   I F SD  N+
Sbjct:   62 SRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGR-RWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNN 371          

Query: 1861 LQSITTVNDPEI-MFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYLQNFTLKELS------DLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            LQ +T  N   +     G++ +     +     L++ + +    FG +H+ E   P D +                 SL   +   N+ +  P   + ++K+L  + T+  +N+F KE+K +  L     P I++      ++ PL    +++++    D   +L    L++ +      D     G   IS   L+++A+QIA GM++L  L  VHRDL+ RN L+  ++  IKI+D  ++   ++ DY                                  +    VLPIRWM W+ +L G F+  SDV++FGVT WE+L LCR QP+ +LT+EQVI N+        R   L  P    +   + +  C       RP F ++  FL   ++
Sbjct:  540 LQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLV-----------------SLDFPL---NVRKGHP--LLVAVKILRPDATKNARNDFLKEVKIMSRLKD---PNIIRLLGVCVQDDPL---CMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQG-PTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV-GENFTIKIADFGMSRNLYAGDY--------------------------------YRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDAL 873          

Query:  226 ARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGS--YLN----LTDFNYDG-----DKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTND 1113
            +R  +S  + AWCP   +  K  ++L +DL  ++++ ++ T+G    G     + SY + Y R+    W  ++ R  Q+ I GN+D      + L P ++AR V+ YP A+   ++CL +++YGC +   ++ Y    G   YL+    L D  YDG      +         G + L+    S++         VGW      +  V++ F F + + F  + +  +   +   +L   ++ +F        E   ++ ++          +V V L   V +F++    F   W++   I F SD  N+
Sbjct:   62 SRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGR-RWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNN 371          

Query:   82 ILISLELLFTATITNT---KSCSDKLLENKNK-VPDSAFTESSY--KEEFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLTDFN---YDGDK--SDSYLSGGLGKLVLNSDTLSKDPF--NTKNDQLVGWDKQKTN-QVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNF---HSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQS 1098
            I + L  ++  T TNT     C +  L  +N  + DS  T SS   K+    + AR  +     AWCP  +I+ K  +FL + L D +++  + T+G   +G     AS Y+I+Y R   S W  Y++R     + GN D  T     LDP I+A  ++  P +    T+C+  +I+GCK+        + DGS L+  DF    ++  +  ++S +  GLG L+ +       PF  N  N+  +GW++  T+ ++ I F F +  NF+ +++  + F ++       I + FS DG T+      Q S  E + +NN    +   V L N  G+ V+IS+ F+S W+ L  + F S
Sbjct:    3 IALVLLAIYGTTTTNTLRIDQCGENALGMQNGDIADSQITASSSFDKQSVGPQNARLHSELASGAWCPKPQINSKSYEFLQVTLNDTFLITSVETQGRYGNGTGREFASHYMIDYLRPG-SQWIRYKNRTGHVYMDGNFDTTTPVIRVLDPPIVASRIRFVPSSKNTRTVCMRAEIHGCKHEGVTYYSTVPDGSRLDTLDFKDSMFEDSQIYTESGIKRGLG-LLTDGFVAQASPFEKNQMNNSWIGWNRDTTDGRITILFEFEEVHNFTDVVL--ATFGNR----IDGIDVIFSQDGKTF--PLFSQISSSERQSLNNTSRRYDFRVPLHNRAGRKVRISIKFSSDWMFLTEVHFTS 350          

Query: 2701 IRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILP-VPNNYSKEFSDFITHCMHFNESTRPSF 2976
            +R+   ++++   F++KSD ++   T +E+   CR++PY ELTNEQ++ N+    L  +   ++P +P  ++ E    +T C   ++  RP+F
Sbjct:  666 LRYSAPESIVNNEFTHKSDAWAVATTVYEMAYQCRQRPYEELTNEQIVDNA-CALLDHQPNAVVPLMPTVFNYEILQLLTRCFRVDQLERPTF 757          

Query:  109 TATITNTKSCSDKLLENKNKVPDSAFT-ESSYKEEFKG-KWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGL--SRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDG---SYLNLTDFNYDGDKSDS-YLSGGLGKLVLNSDTLSKDPFNTKNDQLVGWDKQKTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRV-INNFHSVPVDLKNNVGKFVKISLTF--NSIWIILKYIEFQSDPTN 1110
            T      + CS +L  +  K+ D   +  SS+  +  G + AR        AWCP N+I+   +++L I      ++  + T+G      G   A+++ I+Y R + + W  Y+   + + I  N D        LD AIIAR ++I P +N   T+C+ ++++GC +   ++ Y +D G   S ++  DF+YDG+ ++S +L+GG+GKL      + K+     + + VGW +++   V++ F F++ +N S +LI  S    K+ K FS   + FS +G  + +  V   + ++T   +  +  +PV+  N + K  KI L F  +S W+ +  + F+S+ TN
Sbjct:   16 TVVALELRECSHQLGMSNRKIRDEQISASSSFDLQSTGPQHARAHQESGSGAWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKDDFELETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGCPFDDSLVFYNVDQGDLQSGISYHDFSYDGNLANSPHLTGGIGKLY--DGEVGKNNVFVNHHKWVGWRRKRNGNVKLAFEFSELRNISGILIHTSNEFKKSAKAFSSATVLFSINGKDFSDTIVHFNNPEDTESEVPRWIRIPVN--NRIAKVAKIRLNFGTDSDWLFISEVNFESNHTN 356          

Query: 2332 YLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGD--------ERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQ 3000
            Y++N  LK      Y      I  S  I + +Q+A G+ +LE    VHRD++ RN L+ + +  +KI+D  +A   +S +Y                                 ++    VLPIRWM W+ALL G FS  SDV+ FGVT WE+ +LC ++PY ++T++ V+   NLQ++           R R+ P     SK +++ I  C ++  S RPSF  + + LQ
Sbjct:  601 YMENGDLKS-----YILKNPTIQTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLV-DGEGNVKIADFGMARSLYSQEYY--------------------------------KVEGKFVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVV--ENLQSMSSTGSLKQVLSRPRMCP-----SKLYNEQILPCWNYESSRRPSFENVHLHLQ 786          

Query: 2098 TGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLH-----YETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIG 3015
            +GI T  +F   PE    ++K    + T   + +  +EI+ + + +H   P ++K       D+ +++        + Y+ +  L EL  +      ++ G    + +  +Y+A+QIA GM++L  +  VHRDL+ RN L+  D   IKI+D  +    + SDY          +H+S                          +P+RWM  +A+ QG FS  SDV+SFGVT WE+ +  R QPY   +N+QVI    L A       +L  P+N        +  C H N   RP+F EI   LQ  S+ 
Sbjct:  447 SGIYTSGLFA--PEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDH---PNVIKLIGVCYMDNSLLA-------VFEYMVHGDLHELLKVRVPPADHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLV-GDTRTIKIADFGLMRTSYGSDYYKM-------LHRSW-------------------------MPVRWMSKEAIEQGRFSEASDVWSFGVTLWEIWSFGR-QPYEGASNQQVI---ELVA----NRHLLECPHNCPTNIYSLMVECWHENIERRPTFSEIRSRLQSWSLA 704          

Query: 2098 TGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLH-----YETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIG 3015
            +GI T  +F   PE    ++K    + T   + +  +EI+ + + +H   P ++K       D+ +++        + Y+ +  L EL  +      ++ G    + +  +Y+A+QIA GM++L  +  VHRDL+ RN L+  D   IKI+D  +    + SDY          +H+S                          +P+RWM  +A+ QG FS  SDV+SFGVT WE+ +  R QPY   +N+QVI    L A       +L  P+N        +  C H N   RP+F EI   LQ  S+ 
Sbjct:  606 SGIYTSGLFA--PEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDH---PNVIKLIGVCYMDNSLLA-------VFEYMVHGDLHELLKVRVPPADHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLV-GDTRTIKIADFGLMRTSYGSDYYKM-------LHRSW-------------------------MPVRWMSKEAIEQGRFSEASDVWSFGVTLWEIWSFGR-QPYEGASNQQVI---ELVA----NRHLLECPHNCPTNIYSLMVECWHENIERRPTFSEIRSRLQSWSLA 863          

Query: 2098 TGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLH-----YETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIG 3015
            +GI T  +F   PE    ++K    + T   + +  +EI+ + + +H   P ++K       D+ +++        + Y+ +  L EL  +      ++ G    + +  +Y+A+QIA GM++L  +  VHRDL+ RN L+  D   IKI+D  +    + SDY          +H+S                          +P+RWM  +A+ QG FS  SDV+SFGVT WE+ +  R QPY   +N+QVI    L A       +L  P+N        +  C H N   RP+F EI   LQ  S+ 
Sbjct:  580 SGIYTSGLFA--PEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDH---PNVIKLIGVCYMDNSLLA-------VFEYMVHGDLHELLKVRVPPADHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLV-GDTRTIKIADFGLMRTSYGSDYYKM-------LHRSW-------------------------MPVRWMSKEAIEQGRFSEASDVWSFGVTLWEIWSFGR-QPYEGASNQQVI---ELVA----NRHLLECPHNCPTNIYSLMVECWHENIERRPTFSEIRSRLQSWSLA 837          

Query: 2146 ISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDS--VVVSEHT-ALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLA--IANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIGIK 3021
            + ++  L       L+ EF  + K++  L+    P + +     L D    +V +++  L D   +LQ   + E S L      K +S   L+Y+A+QIA GMKHLE +  VHRDL+ R+ +I   +L +K+  +   I    ++SDY      T              QS P               +PIRWM W+++L G F+ KSDV+SF V  WE+LT  R+QPY  L+++ VI N  L     +   +LP+P N  +E  D +  C   +ES+RPSF EI ++LQ K++G K
Sbjct:  785 LVAVATLRPGANDHLRKEFRSKAKQLAQLSD---PNVARLVGACLRDEPICIVQDYSHCLGDLNQFLQEH-VAETSGL---MAKKSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCII-GPELCVKVCSIGTVINRSAYASDYCQLEGFTGR------------QSQP---------------MPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHLYLQRKNLGFK 1046          

Query:  133 SCSDKLLENKNKVPDSAFTESSYKE--EFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGL--SRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR----MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNT------KNDQLVGW--DKQKTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPT 1107
            +C   L      + D   T SS  +      + AR        AWCP + +     ++L +DL  ++++  I T+G      G     +Y+IEY R     W  +RS   ++ + GN +  +E    L P++ A  V++YPY+  + T+CL  +I GC +   I+ Y     M  G  ++L+D  YDG +   +   GLG+LV       KD F        K  + +GW  D      V+I F F   +N S ++I  +   SK+V++F H ++ FS  G  +  + V Q S     V+++   V + L + +G++V++ L F + W+++  I F S P 
Sbjct:  105 TCKQALGMESGAIADFQITASSAHDMGNVGPQHARLKIDNNGGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPGLKKWIRWRSLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLRAEIVGCAWEEGIVSYSIPKGMQRGMDIDLSDKTYDGYEEGDHYVNGLGQLV--DGQRGKDNFRADINGLGKGYEWIGWRNDTLLGRPVEIIFEFETVRNLSAVIIHTNNMFSKDVQVFVHAKVFFSIGGRHFSGEPV-QFSYMPDLVLDHARDVTIKLHHRLGRYVQLHLYFAARWMMISEITFISAPV 442          

Query: 2146 ISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDS--VVVSEHT-ALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLA--IANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIGIK 3021
            + ++  L       L+ EF  + K++  L+    P + +     L D    +V +++  L D   +LQ   + E S L      K +S   L+Y+A+QIA GMKHLE +  VHRDL+ R+ +I   +L +K+  +   I    ++SDY      T              QS P               +PIRWM W+++L G F+ KSDV+SF V  WE+LT  R+QPY  L+++ VI N  L     +   +LP+P N  +E  D +  C   +ES+RPSF EI ++LQ K++G K
Sbjct:  785 LVAVATLRPGANDHLRKEFRSKAKQLAQLSD---PNVARLVGACLRDEPICIVQDYSHCLGDLNQFLQEH-VAETSGL---MAKKSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCII-GPELCVKVCSIGTVINRSAYASDYCQLEGFTGR------------QSQP---------------MPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHLYLQRKNLGFK 1046          

Query:  133 SCSDKLLENKNKVPDSAFTESSYKE--EFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGL--SRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR----MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNT------KNDQLVGW--DKQKTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPT 1107
            +C   L      + D   T SS  +      + AR        AWCP + +     ++L +DL  ++++  I T+G      G     +Y+IEY R     W  +RS   ++ + GN +  +E    L P++ A  V++YPY+  + T+CL  +I GC +   I+ Y     M  G  ++L+D  YDG +   +   GLG+LV       KD F        K  + +GW  D      V+I F F   +N S ++I  +   SK+V++F H ++ FS  G  +  + V Q S     V+++   V + L + +G++V++ L F + W+++  I F S P 
Sbjct:  105 TCKQALGMESGAIADFQITASSAHDMGNVGPQHARLKIDNNGGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPGLKKWIRWRSLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLRAEIVGCAWEEGIVSYSIPKGMQRGMDIDLSDKTYDGYEEGDHYVNGLGQLV--DGQRGKDNFRADINGLGKGYEWIGWRNDTLLGRPVEIIFEFETVRNLSAVIIHTNNMFSKDVQVFVHAKVFFSIGGRHFSGEPV-QFSYMPDLVLDHARDVTIKLHHRLGRYVQLHLYFAARWMMISEITFISAPV 442          

Query:   79 LILISLELLFTATIT---NTKSCSDKLLENKNKVPDSAFTESSYKE-EFKG-KWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGL--SRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSY----LNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNT------KNDQLVGWDKQKTN----QVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPT 1107
            L++ S  L+  A  T   +  +C+  L      + D+  T SS  +  F G + AR  T     AWCP + + +  +++L +DL   +++  I T+G      G     +Y++EY R     W  +++   ++ + GN +  +E   +L P I A  ++IYPY   + T+CL  +I GC +   I+ Y +  G      ++L+D  YDG++       GLG+LV       KD F T      K  + +GW           V+I F F   +NFS +++  +   +K+V++F H ++ FS  G  +  + V    + +T ++++   V + L + VGK++KI+L F   WI+L  I F S P 
Sbjct:   56 LVIASGCLMLNAPTTMAFDIATCNVPLGMESLLITDAQITASSAHDMAFVGPQHARLKTDNDGGAWCPKHMVSNALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLEYWRPGFDKWQRWKNIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLRAEIVGCPWEEGIVSYSIPKGVQRGMEVDLSDKTYDGNEQGDRYVDGLGQLV--DGQKGKDNFRTDIHGFGKGYEWIGWRNDTPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTKDVQVFVHAKVFFSIGGRYFSGEPVQFSYMPDT-IMDHARDVTIKLHHRVGKYLKINLYFAVKWIMLSEISFISVPA 416          

Query:   79 LILISLELLFTATIT---NTKSCSDKLLENKNKVPDSAFTESSYKE-EFKG-KWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGL--SRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSY----LNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNT------KNDQLVGWDKQKTN----QVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPT 1107
            L++ S  L+  A  T   +  +C+  L      + D+  T SS  +  F G + AR  T     AWCP + + +  +++L +DL   +++  I T+G      G     +Y++EY R     W  +++   ++ + GN +  +E   +L P I A  ++IYPY   + T+CL  +I GC +   I+ Y +  G      ++L+D  YDG++       GLG+LV       KD F T      K  + +GW           V+I F F   +NFS +++  +   +K+V++F H ++ FS  G  +  + V    + +T ++++   V + L + VGK++KI+L F   WI+L  I F S P 
Sbjct:   56 LVIASGCLMLNAPTTMAFDIATCNVPLGMESLLITDAQITASSAHDMAFVGPQHARLKTDNDGGAWCPKHMVSNALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLEYWRPGFDKWQRWKNIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLRAEIVGCPWEEGIVSYSIPKGVQRGMEVDLSDKTYDGNEQGDRYVDGLGQLV--DGQKGKDNFRTDIHGFGKGYEWIGWRNDTPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTKDVQVFVHAKVFFSIGGRYFSGEPVQFSYMPDT-IMDHARDVTIKLHHRVGKYLKINLYFAVKWIMLSEISFISVPA 416          

Query:   79 LILISLELLFTATIT---NTKSCSDKLLENKNKVPDSAFTESSYKE-EFKG-KWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGL--SRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSY----LNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNT------KNDQLVGWDKQKTN----QVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPT 1107
            L++ S  L+  A  T   +  +C+  L      + D+  T SS  +  F G + AR  T     AWCP + + +  +++L +DL   +++  I T+G      G     +Y++EY R     W  +++   ++ + GN +  +E   +L P I A  ++IYPY   + T+CL  +I GC +   I+ Y +  G      ++L+D  YDG++       GLG+LV       KD F T      K  + +GW           V+I F F   +NFS +++  +   +K+V++F H ++ FS  G  +  + V    + +T ++++   V + L + VGK++KI+L F   WI+L  I F S P 
Sbjct:   56 LVIASGCLMLNAPTTMAFDIATCNVPLGMESLLITDAQITASSAHDMAFVGPQHARLKTDNDGGAWCPKHMVSNALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLEYWRPGFDKWQRWKNIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLRAEIVGCPWEEGIVSYSIPKGVQRGMEVDLSDKTYDGNEQGDRYVDGLGQLV--DGQKGKDNFRTDIHGFGKGYEWIGWRNDTPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTKDVQVFVHAKVFFSIGGRYFSGEPVQFSYMPDT-IMDHARDVTIKLHHRVGKYLKINLYFAVKWIMLSEISFISVPA 416          

Query: 1861 LQSITTVNDPEIMFSLGSLFNDL-SYANVALEN-----LKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETG-------AKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARI-LPVPNNYSKEFSDFITHCMHFNESTRPSFVEI 2985
            LQ +T  N     +++ +L  DL S  +VA+E      L + + +    FG +H+ E     D  M+ +  F   E  T+                     + ++K+L  +  +  +N+F KEIK +  L     P I++          V      L     Y++N  L +    H   G       A  +S SNL +MASQIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+LT C++QPY +L++EQVI N+  +   D+R +I LP P          +  C H N   RPSF EI
Sbjct:  541 LQGVTGGN----TYAVPALTMDLLSGKDVAVEEFSRKLLTFKEKLGEGQFGEVHLCEAEGMQD-FMDKDFSFDVTENQTV---------------------LVAVKMLRADANKNARNDFLKEIKIMSRLKD---PNIIRL-------LAVCMSSDPLCMITEYMENGDLNQFLSRHEPEGMIALLSNAPTVSYSNLHHMASQIASGMKYLSSLNFVHRDLATRNCLV-GKNFTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTSSDVWAFGVTLWEMLTFCKEQPYSQLSDEQVIENTG-EFFRDQRRQIYLPQPPMCPDPVYKLMLSCWHRNTKERPSFQEI 859          

Query:   67 RMNFLILISLELLFTA-TITNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMD-------DGSYLNLTDFNYDGDKSDSYLSGGLGKLV-----LNSDTLSKDPFNTKNDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRV-LQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITKTVIPFTQKPN 1173
            +M+F +LI L L     +  N   C   L  ++ ++ D   + SS + E    K+ R      + AWCP      +  ++FL IDL  ++ + ++ T+G    G  +  A +Y I+Y R+  S W  +R+R  ++ I+GN++      + L+P IIAR+V+  P  +    +C+ +++YGC+++  ++ Y          +G ++ L D  YDG  S S ++ GLG+L      L+  TLS           VGW  +      V+I F F + +NF+ + +  +   S+ VK F  +   F  + + ++   V     +D+      F  V V L N++   +K    F+ IW++   I FQSD       + P   +T  P T +P 
Sbjct:   14 KMHFPLLILLYLSGAVQSQVNPGVCRSPLGMSRGQILDEDISASSQWSESTAAKYGRLDCEEGDGAWCPEIPAEPENMKEFLQIDLRSLHFITLVGTQGRHAGGIGNEFAQTYKIKYSRDG-SRWISWRNRQGKEVIEGNRNAYDIVLKDLEPPIIARFVRFMPVIDHSMNVCMRVELYGCEWLDGLVSYNSPLGQQMSLNGQHIYLNDSVYDGAMSYS-MTEGLGQLTDGMCGLDDFTLSHVYNVWPGYDYVGWTNESFPNGYVEIMFEFDRTRNFTTMKVHCNNMFSRRVKTFQKVVCYFRSE-LDWEATPVSFSPVMDDVNPSARF--VTVSLYNHMASAIKCQYYFSDIWMMFSEITFQSDTAMYNTTLTP--PRTDPPLTNQPG 395          

Query: 2146 ISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLI-MNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARI-LPVPNNYSKEFSDFITHCMHFNESTRPSFVEI 2985
            + ++K L ++  +  +N+F KEI+ I  L     P I++      E  PL    +++E+    D   +L    L+E      +  +  IS   LI MASQI+ GMK+L  L  VHRDL+ RN L+ MN+  +IKI+D  ++   +  DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+LTLC++QPY + T+EQVI N+  +   D+  ++ L  P    +     + +C   N   RP+F+EI
Sbjct:  594 LVAVKTLREDADKNARNDFMKEIRIISRLRD---PNIIRLLAVCVESDPL---CMITEYMENGDLNQFLSRHQLQEDG---VQADSTSISYGTLINMASQISSGMKYLSSLNFVHRDLATRNCLVGMNN--IIKIADFGMSRNLYRGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTMASDVWAFGVTLWEILTLCKEQPYAQFTDEQVIENTG-EFFRDQNKQVYLLRPACCPESLYSLMLNCWRRNAKERPTFLEI 836          

Query:  100 LLFTA--TITNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIHDKR-RDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLN-------LTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKND--------QLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASI-------FPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSD 1101
            LLF A  +  N   C   L  N  ++ D   + SS + E    ++ R      + AWCP+        ++FL IDL  ++ + ++ T+G    G  +  A  Y I+Y R+  + W  +R R  ++ I+GN +      + L+P IIAR+V+  P  +    +C+ +++YGC+++  ++ Y    G  +        L D  YDG  S S ++ GLG+L   S  L  D F TK+           VGW         V++TF F + +NF+ + I   +         +  VK+F      F  D          +   D       F  + V L N +   ++    F+ IW++   I FQSD
Sbjct:   12 LLFGAVNSQVNPAVCRYPLGMNGGQIQDEDISASSQWSESTAARYGRLDFDDGDGAWCPDVMAEAHSLKEFLQIDLRTLHFVTLVGTQGRHADGVGNEFAQRYRIKYSRDG-TRWVSWRDRQGRQIIEGNSNAYDIVLKDLEPPIIARFVRFMPVTDPSMIVCMRVELYGCEWLDGLVSYSAPAGQQMTFRGQQIYLNDTVYDGAVSSS-MAEGLGQLTDGSWGL--DDF-TKSQVYGVWPGYDYVGWTNASLPGGSVEMTFEFDRVRNFTSMKINLLVQQVHCNNMYAWGVKMFRQAVCSFRSDADWEPNPVFFKPKADSISPSARF--ITVALGNRMASAIRCRFAFSDIWMMFSEIAFQSD 368          

Query: 1861 LQSITTVNDPEIMFSLGSLF------NDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSF 2976
            LQ +T  N    M+S+ +L        D+S A    + L + + +    FG +H+                  C E   L + L  G     + +Q     + ++K L  + T   +N+F KEIK +  LN+   P I++         PL    +V+E+    D   +L    ++  S L +      +S ++L++M+ QI+ GMK+L  L  VHRDL+ RN L ++  L IKISD  ++   +SSDY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+ TLC++QPY  L++EQVI N+        R   L  P          +  C   + + RPSF
Sbjct:  532 LQGVTGSN----MYSVPALTVDSLTRKDISVAEFPRQRLLFREKLGEGQFGEVHL------------------C-EAEGLAEFLGEGAP---LPEQDGRPVLVAVKQLRADATSNARNDFLKEIKIMSRLNN---PNIIQLLCVCVSSDPL---CMVTEYMENGDLNMFLSQREIE--STLTHANNIPSVSIADLLHMSVQISSGMKYLASLNFVHRDLATRNCL-LDRHLTIKISDFGMSRNLYSSDYY--------------------------------RIQGRAVLPIRWMAWESILLGKFTTASDVWAFGVTLWEIFTLCKEQPYSLLSDEQVIENTGEFFRNQGRQIFLSAPPLCPSSLFKLMMRCWSRDITDRPSF 847          

Query:  136 CSDKLLENKNKVPDSAFTESSYKEEFKG-KWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYL--------NLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQL------VGW--DKQKTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQ--QSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITKTVI 1152
            C   L     ++ +   T SS   +  G ++AR +    E AWC   ++      +L IDL  +  L ++ T+G      G   A  Y +EY R+ +  W  +R+R   + I GN +        L P II R++++ P  +   T+C+ ++++GC +   +M Y   +G  +        +L D  YDG      LSGGLG+L      L  D   ++  +L      VGW  D      V++ F+F + +NF+ + + ++   S  VK+FS +   F    ++  E   ++    ID+      + +VP  LK+     ++    F   W++   I FQS     + IV PT    V+
Sbjct:   11 CRYPLGMEDGRIKNDDITASSQWYDSTGPQYARLNREEGEGAWCAAGQLQPSDVQYLQIDLRQLIFLTVVATQGRYARNSGIEFARKYRLEYSRDGH-RWISWRNRFGNEIIMGNVNTYDTVVRDLHPPIITRFLRLIPVTDAVHTVCMRVELFGCAWQDGLMAYSSPEGQIMMAPGFPITSLNDSTYDGPLERRKLSGGLGQLADGVVGLD-DFVESRQYRLWPGYDYVGWRNDGLGPAYVEMEFQFDRQRNFTSMKVHSNNMFSMGVKIFSSVSCVFKLHLISEWESEPVEFHTVIDDRNPSARYVTVP--LKHRSATALRCRFYFADTWMMFSEISFQS-----VTIVLPTKKPPVL 361          

Query: 1861 LQSITTVNDPEIMFSLGSLF------NDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQ 3000
            LQ +T  N    M+S+ +L        D+S A    + L + + +    FG +H+                  C E   L + L  G     + +Q     + ++K L  + T   +N+F KEIK +  LN+   P I++         PL    +V+E+    D   +L    ++  S L +      +S ++L++M+ QI+ GMK+L  L  VHRDL+ RN L ++  L IKISD  ++   +SSDY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+ TLC++QPY  L++EQVI N+        R   L  P          +  C   + + RPSF ++   L+
Sbjct:  522 LQGVTGSN----MYSVPALTVDSLTRKDISVAEFPRQRLLFREKLGEGQFGEVHL------------------C-EAEGLAEFLGEGAP---LPEQDGRPVLVAVKQLRADATSNARNDFLKEIKIMSRLNN---PNIIQLLCVCVSSDPL---CMVTEYMENGDLNMFLSQREIE--STLTHANNIPSVSIADLLHMSVQISSGMKYLASLNFVHRDLATRNCL-LDRHLTIKISDFGMSRNLYSSDYY--------------------------------RIQGRAVLPIRWMAWESILLGKFTTASDVWAFGVTLWEIFTLCKEQPYSLLSDEQVIENTGEFFRNQGRQIFLSAPPLCPSSLFKLMMRCWSRDITDRPSFNKLHQALR 845          

Query:  136 CSDKLLENKNKVPDSAFTESSYKEEFKG-KWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYL--------NLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQL------VGW--DKQKTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQ--QSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITKTVI 1152
            C   L     ++ +   T SS   +  G ++AR +    E AWC   ++      +L IDL  +  L ++ T+G      G   A  Y +EY R+ +  W  +R+R   + I GN +        L P II R++++ P  +   T+C+ ++++GC +   +M Y   +G  +        +L D  YDG      LSGGLG+L      L  D   ++  +L      VGW  D      V++ F+F + +NF+ + + ++   S  VK+FS +   F    ++  E   ++    ID+      + ++P  LK+     ++    F   W++   I FQS     + IV PT    V+
Sbjct:   23 CRYPLGMEDGRIKNDDITASSQWYDSTGPQYARLNREEGEGAWCAAGQLQPSDVQYLQIDLRQLIFLTVVATQGRYARNSGIEFARKYRLEYSRDGH-RWISWRNRFGNEIIMGNVNTYDTVVRDLHPPIITRFLRLIPVTDAVHTVCMRVELFGCAWQDGLMAYSSPEGQIMMAPGFPITSLNDSTYDGPLERRKLSGGLGQLADGVVGLD-DFVESRQYRLWPGYDYVGWRNDGLGPGYVEMEFQFDRQRNFTSMKVHSNNMFSMGVKIFSSVSCVFKLHLISEWESEPVEFHTVIDDRNPSARYVTIP--LKHRSATALRCRFYFADTWMMFSEISFQS-----VTIVLPTKKPPVL 373          

Query: 1861 LQSITTVNDPEIMFSLGSLF------NDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSF 2976
            LQ +T  N    M+S+ +L        D+S A    + L + + +    FG +H+                  C E   L + L  G     + +Q     + ++K L  + T   +N+F KEIK +  LN+   P I++         PL    +V+E+    D   +L    ++  S L +      +S ++L++M+ QI+ GMK+L  L  VHRDL+ RN L ++  L IKISD  ++   +SSDY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+ TLC++QPY  L++EQVI N+        R   L  P          +  C   + + RPSF
Sbjct:  522 LQGVTGSN----MYSVPALTVDSLTRKDISVAEFPRQRLLFREKLGEGQFGEVHL------------------C-EAEGLAEFLGEGAP---LPEQDGRPVLVAVKQLRADATSNARNDFLKEIKIMSRLNN---PNIIQLLCVCVSSDPL---CMVTEYMENGDLNMFLSQREIE--STLTHANNIPSVSIADLLHMSVQISSGMKYLASLNFVHRDLATRNCL-LDRHLTIKISDFGMSRNLYSSDYY--------------------------------RIQGRAVLPIRWMAWESILLGKFTTASDVWAFGVTLWEIFTLCKEQPYSLLSDEQVIENTGEFFRNQGRQIFLSAPPLCPSSLFKLMMRCWSRDITDRPSF 837          

Query:  136 CSDKLLENKNKVPDSAFTESSYKEEFKG-KWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYL--------NLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQL------VGW--DKQKTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQ--QSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITKTVI 1152
            C   L     ++ +   T SS   +  G ++AR +    E AWC   ++      +L IDL  +  L ++ T+G      G   A  Y +EY R+ +  W  +R+R   + I GN +        L P II R++++ P  +   T+C+ ++++GC +   +M Y   +G  +        +L D  YDG      LSGGLG+L      L  D   ++  +L      VGW  D      V++ F+F + +NF+ + + ++   S  VK+FS +   F    ++  E   ++    ID+      + +VP  LK+     ++    F   W++   I FQS     + IV PT    V+
Sbjct:   23 CRYPLGMEDGRIKNDDITASSQWYDSTGPQYARLNREEGEGAWCAAGQLQPSDVQYLQIDLRQLIFLTVVATQGRYARNSGIEFARKYRLEYSRDGH-RWISWRNRFGNEIIMGNVNTYDTVVRDLHPPIITRFLRLIPVTDAVHTVCMRVELFGCAWQDGLMAYSSPEGQIMMAPGFPITSLNDSTYDGPLERRKLSGGLGQLADGVVGLD-DFVESRQYRLWPGYDYVGWRNDGLGPAYVEMEFQFDRQRNFTSMKVHSNNMFSMGVKIFSSVSCVFKLHLISEWESEPVEFHTVIDDRNPSARYVTVP--LKHRSATALRCRFYFADTWMMFSEISFQS-----VTIVLPTKKPPVL 373          

Query:   82 ILISLELLFT-------ATITNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR--------MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLV-----LNSDTLSKDPFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHS----VPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITKTVIPFTQKPNIPFDNDFFSIPLAYTXXXXXXXXXXXXXXXXPCVTILVRRQKYRNKKCKEALRRHFQEEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCIAPNFS----FINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVND---PEIMFSLGSLFNDLSYANVALE-----NLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFP-EKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILK--FEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARI-LPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKS 3009
            I+IS+ LL+        A +  T  C   L  +   +PD   T SS + E    K+ R  +   + AWCP   +  ++  +FL IDL  ++ + ++ T+G     HG   A  + I Y R+  + W  +R+R  ++ + GN +      + L+P I+AR+++  P  +    +CL +++YGC ++  ++ Y         + +G  + L D  YDG    S ++ GLG+L      L+  TL+ +         VGW  +      V+I F F + +NF+ + +  +   SK VK+F  +Q  F  D   ++       SI  T V+++ +     V V L N++ + +K    F   W++   I FQSD       + P    +V P T  P +  D+    I +   + I+  ++          + +++  +++  K  ++A RR   EE    LT+S     DS              S+ N N R       + S++ S+ ESN   D+   + P++      I   P     T       N    ++  +     A  VP+Y              +  D+VN                                      LQ +T  N    P I   L      LS   VA+E     +L + + +    FG +H+ E         E  ++F               ++ + I +  P +  + ++K+L  +  +  +N+F KEIK +  L       +L     E PL    +++E         Y++N  L +    H E   K   +++L +MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++F VT WE LT CR+QPY E+++EQVI N+  +   D+  ++ LP PN   +     +  C       RPSF EI   LQ +S
Sbjct:    2 IIISMALLYLFRTVAPWALLLFTSVCRYPLGMSGGHIPDEDITASSQWSESTAAKYGRLDSEGGDGAWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDG-TRWISWRNRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSGQQFLLPEGYAIYLNDTIYDGAIGYS-MTEGLGQLTDGVSGLDDFTLTHEYHMWPGYDYVGWSNESFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEWE-----ANSISSTLVLDDANPSARYVTVQLHNHMARAIKCHYYFADSWMMFSEITFQSDAAMYNNSMNPPQPASV-PTTYDPTLKVDDSNTRILIGCLVAIIFILVA---------IIVIILWRQFWQKMLEKASRRMLDEE----LTVSLSLPSDS--------------SMYNTNRR-------HDSVSASEQESNSTYDRIFPLGPDYQEPTRLIRKLPEFTAQTVGEEETGNSAGKSALPA----SADGVPHY--------------AEADIVN--------------------------------------LQGVTGGNTYSVPAITMDL------LSGKEVAVEEFPRKHLTFKEKLGEGQFGEVHLCE--------AEGVEEF---------------LDKDLILETSPGQPTLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIRLLAVCIAEDPL---CMITE---------YMENGDLNQFLSRHRENNVK-FHKNDLRHMAAQIASGMKYLSSLNFVHRDLATRNCLV-GRNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFAVTLWETLTFCREQPYSEMSDEQVIENTG-EFFRDQGKQVYLPKPNICPERVYKLMLSCWRRETKDRPSFQEICQSLQSES 849          

Query:  169 VPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR--------MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLV-----LNSDTLSKDPFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHS----VPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITKTVIPFTQKPNIPFDNDFFSIPLAYTXXXXXXXXXXXXXXXXPCVTILVRRQKYRNKKCKEALRRHFQEEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCIAPNFS----FINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVND---PEIMFSLGSLFNDLSYANVALE-----NLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFP-EKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILK--FEETPLGDSVVVSEHTALDDAYSYLQNFTLKE-LSDLHYETGAKVIS-QSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARI-LPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKS 3009
            +PD   T SS + E    K+ R  +   + AWCP   +  ++  +FL IDL  ++ + ++ T+G     HG   A  + I Y R+  + W  +R+R  ++ + GN +      + L+P I+AR+++  P  +    +CL +++YGC ++  ++ Y         + +G  + L D  YDG    S ++ GLG+L      L+  TL+ +         VGW  +      V+I F F + +NF+ + +  +   SK VK+F  +Q  F  D   ++       SI  T V+++ +     V V L N++ + +K    F   W++   I FQSD       + P    +V P T  P +  D+    I +   + I+  ++          + +++  +++  K  ++A RR   EE    LT+S     DS              S+ N N R       + S++ S+ ESN   D+   + P++      I   P     T       N    ++  +     A  VP+Y              +  D+VN                                      LQ +T  N    P I   L      LS   VA+E     +L + + +    FG +H+ E         E  ++F               ++ + I +  P +  + ++K+L  +  +  +N+F KEIK +  L       +L     E PL    +++E         Y++N  L + LS    E G    +  ++L +MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++F VT WE LT CR+QPY E+++EQVI N+  +   D+  ++ LP PN   +     +  C       RPSF EI   LQ +S
Sbjct:    6 IPDEDITASSQWSESTAAKYGRLDSEGGDGAWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDG-TRWISWRNRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSGQQFLLPEGYAIYLNDTIYDGAIGYS-MTEGLGQLTDGVSGLDDFTLTHEYHMWPGYDYVGWSNESFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEWE-----ANSISSTLVLDDANPSARYVTVQLHNHMARAIKCHYYFADSWMMFSEITFQSDAAMYNNSMNPPQPASV-PTTYDPTLKVDDSNTRILIGCLVAIIFILVA---------IIVIILWRQFWQKMLEKASRRMLDEE----LTVSLSLPSDS--------------SMYNTNRR-------HDSVSASEQESNSTYDRIFPLGPDYQEPTRLIRKLPEFTAQTVGEEETGNSAGKSALPA----SADGVPHY--------------AEADIVN--------------------------------------LQGVTGGNTYSVPAITMDL------LSGKEVAVEEFPRKHLTFKEKLGEGQFGEVHLCE--------AEGVEEF---------------LDKDLILETSPGQPTLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIRLLAVCIAEDPL---CMITE---------YMENGDLNQFLSRQQPEGGLPAATLYTDLRHMAAQIASGMKYLSSLNFVHRDLATRNCLV-GRNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFAVTLWETLTFCREQPYSEMSDEQVIENTG-EFFRDQGKQVYLPKPNICPERVYKLMLSCWRRETKDRPSFQEICQSLQSES 820          

Query: 1792 SHRSIPMYGPAR-VSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALE-----NLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFP-EKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILK--FEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARI-LPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKS 3009
            S   +P Y  A  V++QG      +    T + P I   L      LS   VA+E     +L + + +    FG +H+ E         E  ++F               ++ + I +  P +  + ++K+L  +  +  +N+F KEIK +  L       +L     E PL    +++E+    D    L  F  ++  +         IS ++L +MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++F VT WE LT CR+QPY E+++EQVI N+  +   D+  ++ LP PN   +     +  C       RPSF EI   LQ +S
Sbjct:  413 SADGVPHYAEADIVNLQG------VTGGNTYSVPAITMDL------LSGKEVAVEEFPRKHLTFKEKLGEGQFGEVHLCE--------AEGVEEF---------------LDKDLILETSPGQPTLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIRLLAVCIAEDPL---CMITEYMENGD----LNQFLSRQQPEGGLPAATLPISYTDLRHMAAQIASGMKYLSSLNFVHRDLATRNCLV-GRNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFAVTLWETLTFCREQPYSEMSDEQVIENTG-EFFRDQGKQVYLPKPNICPERVYKLMLSCWRRETKDRPSFQEICQSLQSES 752          

Query:  169 VPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR--------MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLV-----LNSDTLSKDPFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHS----VPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITKTV 1149
            +PD   T SS + E    K+ R  +   + AWCP   +  ++  +FL IDL  ++ + ++ T+G     HG   A  + I Y R+  + W  +R+R  ++ + GN +      + L+P I+AR+++  P  +    +CL +++YGC ++  ++ Y         + +G  + L D  YDG    S ++ GLG+L      L+  TL+ +         VGW  +      V+I F F + +NF+ + +  +   SK VK+F  +Q  F  D   ++       SI  T V+++ +     V V L N++ + +K    F   W++   I FQS       I+E  +  T+
Sbjct:    6 IPDEDITASSQWSESTAAKYGRLDSEGGDGAWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDG-TRWISWRNRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSGQQFLLPEGYAIYLNDTIYDGAIGYS-MTEGLGQLTDGVSGLDDFTLTHEYHMWPGYDYVGWSNESFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEWE-----ANSISSTLVLDDANPSARYVTVQLHNHMARAIKCHYYFADSWMMFSEITFQSGKKQLKNIMEVWVNPTL 348          

Query: 1792 SHRSIPMYGPAR-VSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALE-----NLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFP-EKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILK--FEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARI-LPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKS 3009
            S   +P Y  A  V++QG      +    T + P I   L      LS   VA+E     +L + + +    FG +H+ E         E  ++F               ++ + I +  P +  + ++K+L  +  +  +N+F KEIK +  L       +L     E PL    +++E+    D    L  F  ++  +         IS ++L +MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++F VT WE LT CR+QPY E+++EQVI N+  +   D+  ++ LP PN   +     +  C       RPSF EI   LQ +S
Sbjct:  464 SADGVPHYAEADIVNLQG------VTGGNTYSVPAITMDL------LSGKEVAVEEFPRKHLTFKEKLGEGQFGEVHLCE--------AEGVEEF---------------LDKDLILETSPGQPTLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIRLLAVCIAEDPL---CMITEYMENGD----LNQFLSRQQPEGGLPAATLPISYTDLRHMAAQIASGMKYLSSLNFVHRDLATRNCLV-GRNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFAVTLWETLTFCREQPYSEMSDEQVIENTG-EFFRDQGKQVYLPKPNICPERVYKLMLSCWRRETKDRPSFQEICQSLQSES 803          

Query:  169 VPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR--------MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHS----VPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITK 1143
            +PD   T SS + E    K+ R  +   + AWCP   +  ++  +FL IDL  ++ + ++ T+G     HG   A  + I Y R+  + W  +R+R  ++ + GN +      + L+P I+AR+++  P  +    +CL +++YGC ++  ++ Y         + +G  + L D  YDG      L+ G+    L+  TL+ +         VGW  +      V+I F F + +NF+ + +  +   SK VK+F  +Q  F  D   ++       SI  T V+++ +     V V L N++ + +K    F   W++   I FQS       I+E  +++
Sbjct:    6 IPDEDITASSQWSESTAAKYGRLDSEGGDGAWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDG-TRWISWRNRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSGQQFLLPEGYAIYLNDTIYDGAIGLGQLTDGVSG--LDDFTLTHEYHMWPGYDYVGWSNESFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEWE-----ANSISSTLVLDDANPSARYVTVQLHNHMARAIKCHYYFADSWMMFSEITFQSGKKQLKNIMEVWVSR 340          

Query: 1861 LQSITTVNDPEIMFSLGSLFNDL-SYANVALE-----NLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFP-EKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILK--FEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQ 3000
            LQ +T  N     +S+ ++  DL S   VA+E     +L + + +    FG +H+ E         E  ++F               ++ + I +  P +  + ++K+L  +  +  +N+F KEIK +  L       +L     E PL    +++E+    D    L  F  ++  +         IS ++L +MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++F VT WE LT CR+QPY E+++EQVI N+        +   LP PN   +     +  C       RPSF EI   LQ
Sbjct:  490 LQGVTGGN----TYSVPAITMDLLSGKEVAVEEFPRKHLTFKEKLGEGQFGEVHLCE--------AEGVEEF---------------LDKDLILETSPGQPTLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIRLLAVCIAEDPL---CMITEYMENGD----LNQFLSRQQPEGGLPAATLPISYTDLRHMAAQIASGMKYLSSLNFVHRDLATRNCLV-GRNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFAVTLWETLTFCREQPYSEMSDEQVIENTGEFFRDQGKQVYLPKPNICPERVYKLMLSCWRRETKDRPSFQEICQSLQ 811          

Query:  169 VPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR--------MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLV-----LNSDTLSKDPFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHS----VPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITKTVIPFTQKPNIPFDN 1188
            +PD   T SS + E    K+ R  +   + AWCP   +  ++  +FL IDL  ++ + ++ T+G     HG   A  + I Y R+  + W  +R+R  ++ + GN +      + L+P I+AR+++  P  +    +CL +++YGC ++  ++ Y         + +G  + L D  YDG    S ++ GLG+L      L+  TL+ +         VGW  +      V+I F F + +NF+ + +  +   SK VK+F  +Q  F  D   ++       SI  T V+++ +     V V L N++ + +K    F   W++   I FQSD       + P    +V P T  P +  D+
Sbjct:    6 IPDEDITASSQWSESTAAKYGRLDSEGGDGAWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDG-TRWISWRNRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSGQQFLLPEGYAIYLNDTIYDGAIGYS-MTEGLGQLTDGVSGLDDFTLTHEYHMWPGYDYVGWSNESFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEWE-----ANSISSTLVLDDANPSARYVTVQLHNHMARAIKCHYYFADSWMMFSEITFQSDAAMYNNSMNPPQPASV-PTTYDPTLKVDD 360          

Query: 1801 SIPMYGPARVSIQGPLRNSKLQSITTVNDPEI-MFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSY--LQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            S+P Y  A +          LQ +T  N   +     G++ +     +     L++ + +    FG +H+ E   P D ++ ++     H+ + L                     + ++K+L  + T+  +N+F KE+K +  L     P I++      ++ PL       E+  L+   S   L+N   + LS          IS   L+++ +QIA GM++L  L  VHRDL+ RN L+  ++  IKI+D  ++   ++ DY                                  +    VLPIRWM W+ +L G F+  SDV++FGVT WE+L LCR QP+ +LT+EQVI N+        R   L  P    +   + +  C       RP F ++  FL   ++
Sbjct:  526 SVPHYAEADIVT--------LQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVEDPQD-LVSSDFPISVHKGHPL---------------------LVAVKILRPDATKNARNDFLKEVKIMSRLKD---PNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSARQLENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLV-GENFTIKIADFGMSRNLYAGDY--------------------------------YRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCWSREPEQRPPFAQLHRFLADDAL 871          

Query:  226 ARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLT-------DFNYDGDKSDSYLSGGL-----GKLVLNSDTLSKDPFNTKNDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTND 1113
            +R  +S  + AWCP   +  K  ++L +DL  ++++ ++ T+G    G     + SY + Y R+    W +++ R  Q+ I GN+D      + L P ++AR V+ YP A+   ++CL +++YGC +   ++ Y    G  + L+       D  YDG  +     GGL     G + L+    S++         VGW  Q   T  V++ F F + + F  + +  +   +   +L   ++ +F        E   ++ ++  +       ++ V L  +VG+F++    F   W++   I F SD  ND
Sbjct:   63 SRLESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGR-RWMDWKDRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMQLSEVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWPGYDYVGWSNQSFPTGYVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFKRGPAMAWEGEPVRHALGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDVVND 373          

Query: 1801 SIPMYGPARVSIQGPLRNSKLQSITTVNDPEI-MFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSY--LQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            S+P Y  A +          LQ +T  N   +     G++ +     +     L++ + +    FG +H+ E   P D ++ ++     H+ + L                     + ++K+L  + T+  +N+F KE+K +  L     P I++      ++ PL       E+  L+   S   L+N   + LS          IS   L+++ +QIA GM++L  L  VHRDL+ RN L+  ++  IKI+D  ++   ++ DY                                  +    VLPIRWM W+ +L G F+  SDV++FGVT WE+L LCR QP+ +LT+EQVI N+        R   L  P    +   + +  C       RP F ++  FL   ++
Sbjct:  563 SVPHYAEADIVT--------LQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVEDPQD-LVSSDFPISVHKGHPL---------------------LVAVKILRPDATKNARNDFLKEVKIMSRLKD---PNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSARQLENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLV-GENFTIKIADFGMSRNLYAGDY--------------------------------YRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCWSREPEQRPPFAQLHRFLADDAL 908          

Query:  226 ARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLT-------DFNYDGDKSDSYLSGGL-----GKLVLNSDTLSKDPFNTKNDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTND 1113
            +R  +S  + AWCP   +  K  ++L +DL  ++++ ++ T+G    G     + SY + Y R+    W +++ R  Q+ I GN+D      + L P ++AR V+ YP A+   ++CL +++YGC +   ++ Y    G  + L+       D  YDG  +     GGL     G + L+    S++         VGW  Q   T  V++ F F + + F  + +  +   +   +L   ++ +F        E   ++ ++  +       ++ V L  +VG+F++    F   W++   I F SD  ND
Sbjct:   63 SRLESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGR-RWMDWKDRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMQLSEVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWPGYDYVGWSNQSFPTGYVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFKRGPAMAWEGEPVRHALGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDVVND 373          

Query: 1801 SIPMYGPARVSIQGPLRNSKLQSITTVNDPEI-MFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSY--LQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            S+P Y  A +          LQ +T  N   +     G++ +     +     L++ + +    FG +H+ E   P D ++ ++     H+ + L                     + ++K+L  + T+  +N+F KE+K +  L     P I++      ++ PL       E+  L+   S   L+N   + LS          IS   L+++ +QIA GM++L  L  VHRDL+ RN L+  ++  IKI+D  ++   ++ DY                                  +    VLPIRWM W+ +L G F+  SDV++FGVT WE+L LCR QP+ +LT+EQVI N+        R   L  P    +   + +  C       RP F ++  FL   ++
Sbjct:  563 SVPHYAEADIVT--------LQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVEDPQD-LVSSDFPISVHKGHPL---------------------LVAVKILRPDATKNARNDFLKEVKIMSRLKD---PNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSARQLENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLV-GENFTIKIADFGMSRNLYAGDY--------------------------------YRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCWSREPEQRPPFAQLHRFLADDAL 908          

Query:  226 ARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLT-------DFNYDGDKSDSYLSGGL-----GKLVLNSDTLSKDPFNTKNDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTND 1113
            +R  +S  + AWCP   +  K  ++L +DL  ++++ ++ T+G    G     + SY + Y R+    W +++ R  Q+ I GN+D      + L P ++AR V+ YP A+   ++CL +++YGC +   ++ Y    G  + L+       D  YDG  +     GGL     G + L+    S++         VGW  Q   T  V++ F F + + F  + +  +   +   +L   ++ +F        E   ++ ++  +       ++ V L  +VG+F++    F   W++   I F SD  ND
Sbjct:   63 SRLESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGR-RWMDWKDRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMQLSEVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWPGYDYVGWSNQSFPTGYVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFKRGPAMAWEGEPVRHALGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDVVND 373          

Query: 1801 SIPMYGPARVSIQGPLRNSKLQSITTVNDPEI-MFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSY--LQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            S+P Y  A +          LQ +T  N   +     G++ +     +     L++ + +    FG +H+ E   P D ++ ++     H+ + L                     + ++K+L  + T+  +N+F KE+K +  L     P I++      ++ PL       E+  L+   S   L+N   + LS          IS   L+++ +QIA GM++L  L  VHRDL+ RN L+  ++  IKI+D  ++   ++ DY                                  +    VLPIRWM W+ +L G F+  SDV++FGVT WE+L LCR QP+ +LT+EQVI N+        R   L  P    +   + +  C       RP F ++  FL   ++
Sbjct:  563 SVPHYAEADIVT--------LQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVEDPQD-LVSSDFPISVHKGHPL---------------------LVAVKILRPDATKNARNDFLKEVKIMSRLKD---PNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSARQLENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLV-GENFTIKIADFGMSRNLYAGDY--------------------------------YRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCWSREPEQRPPFAQLHRFLADDAL 908          

Query:  226 ARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLT-------DFNYDGDKSDSYLSGGL-----GKLVLNSDTLSKDPFNTKNDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTND 1113
            +R  +S  + AWCP   +  K  ++L +DL  ++++ ++ T+G    G     + SY + Y R+    W +++ R  Q+ I GN+D      + L P ++AR V+ YP A+   ++CL +++YGC +   ++ Y    G  + L+       D  YDG  +     GGL     G + L+    S++         VGW  Q   T  V++ F F + + F  + +  +   +   +L   ++ +F        E   ++ ++  +       ++ V L  +VG+F++    F   W++   I F SD  ND
Sbjct:   63 SRLESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGR-RWMDWKDRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMQLSEVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWPGYDYVGWSNQSFPTGYVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFKRGPAMAWEGEPVRHALGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDVVND 373          

Query: 1801 SIPMYGPARVSIQGPLRNSKLQSITTVNDPEI-MFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSY--LQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            S+P Y  A +          LQ +T  N   +     G++ +     +     L++ + +    FG +H+ E   P D ++ ++     H+ + L                     + ++K+L  + T+  +N+F KE+K +  L     P I++      ++ PL       E+  L+   S   L+N   + LS          IS   L+++ +QIA GM++L  L  VHRDL+ RN L+  ++  IKI+D  ++   ++ DY                                  +    VLPIRWM W+ +L G F+  SDV++FGVT WE+L LCR QP+ +LT+EQVI N+        R   L  P    +   + +  C       RP F ++  FL   ++
Sbjct:  563 SVPHYAEADIVT--------LQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVEDPQD-LVSSDFPISVHKGHPL---------------------LVAVKILRPDATKNARNDFLKEVKIMSRLKD---PNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSARQLENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLV-GENFTIKIADFGMSRNLYAGDY--------------------------------YRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCWSREPEQRPPFAQLHRFLADDAL 908          

Query:  226 ARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLT-------DFNYDGDKSDSYLSGGL-----GKLVLNSDTLSKDPFNTKNDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTND 1113
            +R  +S  + AWCP   +  K  ++L +DL  ++++ ++ T+G    G     + SY + Y R+    W +++ R  Q+ I GN+D      + L P ++AR V+ YP A+   ++CL +++YGC +   ++ Y    G  + L+       D  YDG  +     GGL     G + L+    S++         VGW  Q   T  V++ F F + + F  + +  +   +   +L   ++ +F        E   ++ ++  +       ++ V L  +VG+F++    F   W++   I F SD  ND
Sbjct:   63 SRLESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGR-RWMDWKDRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMQLSEVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWPGYDYVGWSNQSFPTGYVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFKRGPAMAWEGEPVRHALGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDVVND 373          

Query: 1687 NNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSH--RSIPMYGPAR-----VSIQGPLRNSKLQSITTVNDPEIM----------FSLGSLFNDL-SYANVALEN-----LKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDS--VVVSEHTALDDAYSYLQNFTLKELSDLH-----YETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFL 2997
            NN   + S+    S YD + P+  +        EPS   R +P + P         +  P++ S  + +    + +I+          +S+ ++  DL S  +VA+E      L + + +    FG +H+ E        +E  +KF+  ++  L  S    +             + ++K+L  +  +  +N+F KEIK +  L     P I+      + D    +++E         Y++N  L +    H       +  + +S +NL +MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE  T C++QPY +L++EQVI N+        R   LP P          +  C   +   RPSF EI + L
Sbjct:  456 NNRSSSPSEQGSNSTYDRIFPLRPD------YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCE--------VEGMEKFKDKDF-ALDVSANQPV-------------LVAVKMLRADANKNARNDFLKEIKIMSRLKD---PNIIHLLAVCITDDPLCMITE---------YMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV-GKNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849          

Query:  121 TNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR--------MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKND-------QLVGW-DKQKTNQ-VQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRV-LQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSD 1101
             N   C   L  +  ++PD   T SS + E    K+ R  +   + AWCP   +  D  ++FL IDL  ++ + ++ T+G     HG   A  Y I Y R+  + W  +R+R  ++ + GN +      + L+P I+AR+V+  P  +    +C+ +++YGC ++  ++ Y         +  GS + L D  YDG    S ++ GLG+L      L  D F   ++         VGW ++  TN  ++I F F + +NF+ + +  +   +K VK+F  +Q  F  +   ++   +     +D+      F +VP  L + +   +K    F   W++   I FQSD
Sbjct:   25 VNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDG-TRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYS-MTEGLGQLTDGVSGL--DDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVP--LHHRMASAIKCQYHFADTWMMFSEITFQSD 367          

Query: 1801 SIPMYGPARVSIQGPLRNSKLQSITTVNDPEI-MFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSY--LQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            S+P Y  A +          LQ +T  N   +     G++ +     +     L++ + +    FG +H+ E   P D ++ ++     H+ + L                     + ++K+L  + T+  +N+F KE+K +  L     P I++      ++ PL       E+  L+   S   L+N   + LS          IS   L+++ +QIA GM++L  L  VHRDL+ RN L+  ++  IKI+D  ++   ++ DY                                  +    VLPIRWM W+ +L G F+  SDV++FGVT WE+L LCR QP+ +LT+EQVI N+        R   L  P    +   + +  C       RP F ++  FL   ++
Sbjct:  563 SVPHYAEADIVT--------LQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVEDPQD-LVSSDFPISVHKGHPL---------------------LVAVKILRPDATKNARNDFLKEVKIMSRLKD---PNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSARQLENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLV-GENFTIKIADFGMSRNLYAGDY--------------------------------YRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCWSREPEQRPPFAQLHRFLADDAL 908          

Query:  226 ARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLT-------DFNYDGDKSDSYLSGGL-----GKLVLNSDTLSKDPFNTKNDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTND 1113
            +R  +S  + AWCP   +  K  ++L +DL  ++++ ++ T+G    G     + SY + Y R+    W +++ R  Q+ I GN+D      + L P ++AR V+ YP A+   ++CL +++YGC +   ++ Y    G  + L+       D  YDG  +     GGL     G + L+    S++         VGW  Q   T  V++ F F + + F  + +  +   +   +L   ++ +F        E   ++ ++  +       ++ V L  +VG+F++    F   W++   I F SD  ND
Sbjct:   63 SRLESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGR-RWMDWKDRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMQLSEVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWPGYDYVGWSNQSFPTGYVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFKRGPAMAWEGEPVRHALGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDVVND 373          

Query: 1861 LQSITTVND---PEIMFSLGSLFNDLSYANVALEN-----LKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGA----KVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFL 2997
            LQ +T  N    P +   L      LS  +VA+E      L + + +    FG +H+ E        +E  +KF+  ++  L  S    +             + ++K+L  +  +  +N+F KEIK +  L     P I++        +V ++E   L     Y++N  L +    H    +      +S +NL +MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE  T C++QPY +L++EQVI N+        R   LP P          +  C       RPSF EI + L
Sbjct:  529 LQGVTGGNTYCVPAVTMDL------LSGKDVAVEEFPRKLLAFKEKLGEGQFGEVHLCE--------VEGMEKFKDKDF-ALDVSANQPV-------------LVAVKMLRADANKNARNDFLKEIKIMSRLKD---PNIIRLL------AVCITED-PLCMITEYMENGDLNQFLSRHEPLSSCSSDATVSYANLKFMATQIASGMKYLSSLNFVHRDLATRNCLV-GKNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQIYLPQPALCPDSVYKLMLSCWRRETKHRPSFQEIHLLL 848          

Query:  121 TNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYR--------MDDGSYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKND-------QLVGW-DKQKTNQ-VQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRV-LQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSD 1101
             N   C   L  +   +PD   T SS + E    K+ R  +   + AWCP   +  D  ++FL IDL  ++ + ++ T+G     HG   A  Y I Y R+  S W  +R+R  ++ + GN +      + L+P I+AR+V++ P  +    +C+ +++YGC ++  ++ Y         +  GS + L D  YDG    S ++ GLG+L      L  D F   ++         VGW ++  TN  ++I F F + +NF+ + +  +   +K VK+F  +Q  F  +   ++   V     +D+      F +VP  L + +   +K    F   W++   I FQSD
Sbjct:   25 VNPAICRYPLGMSGGHIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVQPDDLKEFLQIDLRTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDG-SRWISWRNRHGKQVLDGNSNPYDVFLKDLEPPIVARFVRLIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYS-MTEGLGQLTDGVSGL--DDFTQTHEYHVWPGYDYVGWRNESATNGFIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPTAVYFPLVLDDVNPSARFVTVP--LHHRMASAIKCQYHFADTWMMFSEITFQSD 367          

Query: 1861 LQSITTVNDPEI-MFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYLQNFTLKELS------DLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            LQ +T  N   +     G++ +     +     L++ + +    FG +H+ E   P D +                 SL   +   N+ +  P   + ++K+L  + T+  +N+F KE+K +  L     P I++      ++ PL    +++++    D   +L    L++ +      D     G   IS   L+++A+QIA GM++L  L  VHRDL+ RN L+  ++  IKI+D  ++   ++ DY                                  +    VLPIRWM W+ +L G F+  SDV++FGVT WE+L LCR QP+ +LT+EQVI N+        R   L  P    +   + +  C       RP F ++  FL   ++
Sbjct:  573 LQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLV-----------------SLDFPL---NVRKGHP--LLVAVKILRPDATKNARNDFLKEVKIMSRLKD---PNIIRLLGVCVQDDPL---CMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQG-PTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV-GENFTIKIADFGMSRNLYAGDY--------------------------------YRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDAL 906          

Query:  238 TSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGS--YLN----LTDFNYDG-----DKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTND 1113
            +S  + AWCP   +  K  ++L +DL  ++++ ++ T+G    G     + SY + Y R+    W  ++ R  Q+ I GN+D      + L P ++AR V+ YP A+   ++CL +++YGC +   ++ Y    G   YL+    L D  YDG      +         G + L+    S++         VGW      +  V++ F F + + F  + +  +   +   +L   ++ +F        E   ++ ++          +V V L   V +F++    F   W++   I F SD  N+
Sbjct:   62 SSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGR-RWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNN 367          

Query: 1861 LQSITTVNDPEI-MFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYLQNFTLKELS------DLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            LQ +T  N   +     G++ +     +     L++ + +    FG +H+ E   P D +                 SL   +   N+ +  P   + ++K+L  + T+  +N+F KE+K +  L     P I++      ++ PL    +++++    D   +L    L++ +      D     G   IS   L+++A+QIA GM++L  L  VHRDL+ RN L+  ++  IKI+D  ++   ++ DY                                  +    VLPIRWM W+ +L G F+  SDV++FGVT WE+L LCR QP+ +LT+EQVI N+        R   L  P    +   + +  C       RP F ++  FL   ++
Sbjct:  577 LQGVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLV-----------------SLDFPL---NVRKGHP--LLVAVKILRPDATKNARNDFLKEVKIMSRLKD---PNIIRLLGVCVQDDPL---CMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQG-PTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV-GENFTIKIADFGMSRNLYAGDY--------------------------------YRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDAL 910          

Query:  226 ARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGS--YLN----LTDFNYDG-----DKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTND 1113
            +R  +S  + AWCP   +  K  ++L +DL  ++++ ++ T+G    G     + SY + Y R+    W  ++ R  Q+ I GN+D      + L P ++AR V+ YP A+   ++CL +++YGC +   ++ Y    G   YL+    L D  YDG      +         G + L+    S++         VGW      +  V++ F F + + F  + +  +   +   +L   ++ +F        E   ++ ++          +V V L   V +F++    F   W++   I F SD  N+
Sbjct:   62 SRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGR-RWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNN 371          

Query:  118 ITNTKSCSDKLLENKNKVPDSAFT-ESSYKEEFKG-KWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSY--------LNLTDFNYDGDKSDSYLSGGLGKLV--------LNSDTLSKDPFNTKNDQLVGWDKQKTNQ---VQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTN-DIRIVEPTITKTV-----------IPFTQKPNIPFDNDF------FSIPLAYTXXXXXXXXXXXXXXXXPCVT----ILVRRQKYRNKKCKEALRRHFQEEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESN---CNSDKPQCIAPNFSFINTCPIIN------PLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNP---NESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF--EETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIG 3015
            I +   C   L      +PD A T  SSYKE   G + AR        AWCP N ++    ++L IDL  + ++  + T+G   +G        +++EY+RE +  W  +R+R   +    N +  T +   + P IIA+ V+  PY     T+C+ +++YGC +   ++ Y M  G          L   DF YDG   + +L  G+G+L+          SD  ++     K  + VGW  +  +    VQI F+F   +NF+ L I A+ F  K+V +FS   + FS  G+ Y +   +    +    +    +V + L+N VGK+VK+ L F+  W+++  + F+S+ T  ++ +  P +T  V           +P  +  NI    D        S+           I II+  +    VT     ++     R+K+ K+   RH  +   R + L+    ++  N      VSN N               +Y S+A  + ES+   CN  +  C +P++S      +        P  +   S S DY+    T   S     +P +     +  S  N  +   M N ++  P   +  +A  +  H ++P       ++QG   N    ++  V + E++ +L     + +      ENL+++  +    FG +H+ E +     I +        +Y   R S  T             K + ++K+L +N   + + +F KEIK +  L       +L     E PL    ++ E+    D   +L +   +  S +   T AK +S   L+YMASQIA GMK+LE L +VHRDL+ RN L+   +  IKISD  ++   +S+DY                                  I    VLPIRWM W+++L G F+ KSDV+SF VT WE+LT  + QP+  LT+EQVI N+      D +   L +P N  KE  D +  C + NE+ RP+F E+ MFLQ K++G
Sbjct:   10 IVHAGQCQTALGMESGAIPDDAITASSSYKEGSVGPESARIRKEWQGGAWCPKNILNKNSYEYLQIDLYKLMVITKVETQGRFGNGLGQEFTEKFLLEYQREDDGEWIRFRNRQAAEHFSANYNTHTAEMNEVSPPIIAKRVRFIPYTETPRTVCMRVELYGCTWNDGVLSYSMPQGDRRGKHSSDELAFLDFTYDGIIKEDHLYNGIGQLMDGEEGQANFRSDLQAR---GIKGYEWVGWKTENPDDNIPVQIVFKFDDVRNFTLLNIHANNFYDKDVSVFSMAHVYFSVSGIYY-QPNYIDHKFERDSWMEYARTVSIPLENRVGKYVKVELFFDRKWMLISEVSFKSEVTKANVTMELPPLTPAVHTTKAPTIGERLPVDRNINIQIGQDSQQHVEDRSVQTKEATTENDMIGIIVGTLSALIVTLLVVAVIVIILIRHKRSKQNNNRHCLKPVERHIALNMNGMRNMQNG----KVSNGN---------------MYNSVAQEEMESDRELCNGGEKLCKSPSYSEPQDSLVGGRDLPDLPGCAAGNSDSRDYAVPDVTK--SALIVALPPHTQTP-IRVSPANNGTPIMMNNCLTEKPPTYDALYAAADIVHVNVPNIP----NLQGVSGN----NVYAVPNAELLLTL-----EHAVVQFPRENLQFVDVLGEGQFGEVHLCEAVNVDGYISD--------DYFMNRASTHT------------PKVLVAVKMLRRNADDRARADFSKEIKIMSQLKDPNIVRVLGVCTREEPL---CMIVEYMKYGDLNQFLLDHVPE--SPVAMATNAKTLSYGCLVYMASQIASGMKYLESLNMVHRDLATRNCLV-GTNYTIKISDFGMSRSLYSADY--------------------------------YRIEGRAVLPIRWMAWESILLGKFTTKSDVWSFAVTLWEILTFAKDQPFDTLTDEQVIENAGHYYRNDNKEVYLSLPPNCPKEIYDLMVECWNRNEACRPTFREVHMFLQRKNMG 937          

Query:  100 LLFTATITNTKSCSDKLLENKNKVPDSAFTESS-------------YKEEFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGL--SRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDG----SYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQLVGWDKQ-KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTND---IRIVEPTITKTVIPFTQKPNIPFDNDFFSIPLAYTXXXXXXXXXXXXXXXXPCVTILVRRQKYRNKKCKEALRRHFQEEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCI--APNFSFINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIIN-SNLQALGD-----ERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
             +  A +  T  C   L      +PD   T SS               +E KG            AWCP ++I  +  ++L ++L  ++++    T+G   +  G   A +Y++EY R     W  YR    Q+ + GN +   EK   L P I A  ++  PY++   T+C+ +++YGC +   I+ Y M  G    + + LTD  YDG   +  L GGLG+LV       +     +N   VGW K+ + N   ITF F + + FS +    +    ++V++FS   I FS  G  + ++ + + S  E  +  +  +V + L + +GK+V+I L F + WI++  + F SD          V+ T  K     +   ++P        PL   +V+ +   +++LL     V + +   ++R++KC       F    A+  T+SQ++      NP                  MM ++ +     G D +S+   +  Q +  AP FS+      +            D+   S T L S+ ++Y       A    S   L +   + + +S    +   + +P      M   AR S    +R+    S  + +  E++  L       +        L+ I  ++   FG++++ E     D + E N                 GI T        EK++ ++K L  + T K + +F ++++ + +L+      +L    TP     VV E+  L D  ++L++              A   S  +L+++A+QIA GM++LE L  VHRDL+ RN+LI      IKISD    NE +  DY                                 ++   + +P+RW  W+ LL G+++ KSDV++F VT  E+ T CR++PY  LT+ +V+ N ++LQA        ERA  +P      ++  + +  C   ++  RP FVE+++FLQ KS+
Sbjct:    7 FILIAELNKTAQCIAPLGMENGLIPDKDLTASSSFNDGNVGPQNGRLNQEIKGG-----------AWCPKSQITTESTEWLEVNLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRGADGQEILTGNANTYLEKKNHLQPPIWASKIRFIPYSSHRRTVCMRVELYGCYWSVGIVAYSMPKGDKRSNGIELTDMTYDGQWGEE-LRGGLGQLVDGQYGGDEIREAARNSAWVGWKKESRPNPPVITFEFDKVREFSAVHFYCNNRFMRDVQVFSEAIISFSIGGRHFQDEPI-RYSYVEDSIFESSRNVSIKLHHRIGKWVRIELRFAASWILISEVVFDSDVAQGNYTPETVKATGGKEKTKSSTTKDLPISTAHQEDPLYMAIVVGVLTALVILL----AVAVFLIVHRHRHRKC-------FASPLAKS-TISQKRTVTDTYNPC--------------GTSMMPDNKMILD-CGLDVKSDEYQEPYQALKCAPYFSYSTVLLEM-----------KDFVKDSSTPL-SDSSNY-----EYAVPELSSAPLLTKRRLADSLSGRTTDPLTDHDPE-----MGLGARRSAPASIRSK--HSTRSPSQQEVLTDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAE----ADGVPEYN-----------------GIVTS-------EKRLVAVKFLCHDATPKEREDFERDVRILAALSSPHLARVLGACRTP--PLAVVLEYLELGDLCAFLRS--------------APPPSIGSLLHIATQIATGMQYLESLNFVHRDLAARNILI-GKGYQIKISDFGTDNEAYICDYY--------------------------------KVEGRVPIPLRWAAWETLL-GHYTTKSDVWAFAVTLHEIFTFCRRRPYEHLTDNEVLENLAHLQADDGLFECIERAPGIP------RDLYELMRECWKHDQLERPDFVEVNLFLQRKSL 860          

Query:  121 TNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLTDF-------NYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTK-------NDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITKTVIPFTQKPNIPFDNDFFSIPLAYTXXXXXXXXXXXXXXXXPCVTILVRRQKYRNKKCKEALRRHFQEEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCIAPNFS----FINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVND---PEIMFSLGSLFNDLSYANVALEN-----LKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQ--ISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETG-------AKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEI 2985
             NT  C   L  +  ++ D   + SS + E    ++ R      + AWCP   +  D  ++FL IDL  ++ + ++ T+G    G  +  A  Y I+Y R+  S W  +R+R  ++ I+GN++      + L+P IIAR+V+  P  +    +C+ +++YGC+++  ++ Y    G  +NL  F        YDG  + S ++ GLG+  L       D F              VGW  +   +  V+I F F + +NF+ + +  +   S +VK+F  +   F  +        +   + DE      F  V V L N++   +K    F   W++   I FQSD       + P   KT +P    PN P   D           I+I  L+ ++ I +  + I++ RQ ++ K  ++A RR   +E    L++  + F           V N N                  S   S+ ES+   ++   + P++     FI   P   P     GS +   S TS  ++  +G   VP+Y              +  D+VN                                      LQ +T  N    P +   L      LS  +VA+E      L + + +    FG +H+ E         E   KF               ++ E +F   PE Q  + ++K+L  +  +  +++F KEIK +  L     P I++     L    + S+   +     Y++N  L +    H   G       A  +S SNL YMA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+L  C++QPY +LT+EQVI N+       +R   LP P          +  C   N   RPSF EI
Sbjct:   25 VNTGVCRYPLGMSGGQIQDEDISASSQWSESTAARYGRLDFEEGDGAWCPETTVEPDSLKEFLQIDLRSLHFITLVGTQGRHAGGIGNEFAQMYKIKYSRDG-SRWISWRNRQGEQVIEGNRNTYDIVLKDLEPPIIARFVRFMPVTDHSMNVCMRVELYGCEWLDGLVSYNAPAGEQMNLPSFLVYVNDSVYDGAVTHS-MTEGLGQ--LTDGVFGLDDFTNSCVYKAWPGYDYVGWSNESFPSGYVEIMFEFDRIRNFTTMKVHCNNMFSNHVKVFRQVLCHFRSESDWEPSPLLFSPAADEKNPSARF--VTVSLANHMASAIKCQFYFADTWMLFSEITFQSDTAMYNTTLAP--PKTGLP----PNTPPGEDPTHKVDDSNTRILIGCLVAIIFILVAIIVIMLWRQVWQ-KMLEKASRRMLDDELITSLSIQSETF-----------VYNHN-----------------QSSGASEQESSSTYERIFPLGPDYQEPSRFICKLPEFAPSLEEPGSTAASKSTTS--TVAQDG---VPHY--------------AEADVVN--------------------------------------LQGVTGSNTYAIPAVTMDL------LSGKDVAVEEFPRKMLTFKEKLGEGQFGEVHLCE--------AEGMHKF---------------MDKEFLF-DVPEDQPVLVAVKMLRSDANKNARSDFLKEIKIMSRLKD---PNIIR-----LLAVCICSDPLCM--ITEYMENGDLNQFLSRHEPEGQLALISNASTVSFSNLCYMAAQIASGMKYLSSLNFVHRDLATRNCLV-GKNFTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWEILNFCKEQPYSQLTDEQVIENTGEFFRDQKRQIYLPQPGLCPDSLYKVMLSCWRRNAKERPSFQEI 849          

Query:  121 TNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLTDF-------NYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTK-------NDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITKTVIPFTQKPNIPFDNDFFSIPLAYTXXXXXXXXXXXXXXXXPCVTILVRRQKYRNKKCKEALRRHFQEEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCIAPNFS----FINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVND---PEIMFSLGSLFNDLSYANVALEN-----LKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQ--ISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETG-------AKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEI 2985
             NT  C   L  +  ++ D   + SS + E    ++ R      + AWCP   +  D  ++FL IDL  ++ + ++ T+G    G  +  A  Y I+Y R+  S W  +R+R  ++ I+GN++      + L+P IIAR+V+  P  +    +C+ +++YGC+++  ++ Y    G  +NL  F        YDG  + S ++ GLG+  L       D F              VGW  +   +  V+I F F + +NF+ + +  +   S +VK+F  +   F  +        +   + DE      F  V V L N++   +K    F   W++   I FQSD       + P   KT +P    PN P   D           I+I  L+ ++ I +  + I++ RQ ++ K  ++A RR   +E    L++  + F           V N N                  S   S+ ES+   ++   + P++     FI   P   P     GS +   S TS  ++  +G   VP+Y              +  D+VN                                      LQ +T  N    P +   L      LS  +VA+E      L + + +    FG +H+ E         E   KF               ++ E +F   PE Q  + ++K+L  +  +  +++F KEIK +  L     P I++     L    + S+   +     Y++N  L +    H   G       A  +S SNL YMA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+L  C++QPY +LT+EQVI N+       +R   LP P          +  C   N   RPSF EI
Sbjct:   20 VNTGVCRYPLGMSGGQIQDEDISASSQWSESTAARYGRLDFEEGDGAWCPETTVEPDSLKEFLQIDLRSLHFITLVGTQGRHAGGIGNEFAQMYKIKYSRDG-SRWISWRNRQGEQVIEGNRNTYDIVLKDLEPPIIARFVRFMPVTDHSMNVCMRVELYGCEWLDGLVSYNAPAGEQMNLPSFLVYVNDSVYDGAVTHS-MTEGLGQ--LTDGVFGLDDFTNSCVYKAWPGYDYVGWSNESFPSGYVEIMFEFDRIRNFTTMKVHCNNMFSNHVKVFRQVLCHFRSESDWEPSPLLFSPAADEKNPSARF--VTVSLANHMASAIKCQFYFADTWMLFSEITFQSDTAMYNTTLAP--PKTGLP----PNTPPGEDPTHKVDDSNTRILIGCLVAIIFILVAIIVIMLWRQVWQ-KMLEKASRRMLDDELITSLSIQSETF-----------VYNHN-----------------QSSGASEQESSSTYERIFPLGPDYQEPSRFICKLPEFAPSLEEPGSTAASKSTTS--TVAQDG---VPHY--------------AEADVVN--------------------------------------LQGVTGSNTYAIPAVTMDL------LSGKDVAVEEFPRKMLTFKEKLGEGQFGEVHLCE--------AEGMHKF---------------MDKEFLF-DVPEDQPVLVAVKMLRSDANKNARSDFLKEIKIMSRLKD---PNIIR-----LLAVCICSDPLCM--ITEYMENGDLNQFLSRHEPEGQLALISNASTVSFSNLCYMAAQIASGMKYLSSLNFVHRDLATRNCLV-GKNFTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWEILNFCKEQPYSQLTDEQVIENTGEFFRDQKRQIYLPQPGLCPDSLYKVMLSCWRRNAKERPSFQEI 844          

Query:  466 GNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDG----SYLNLTDFNYDGDKSDSYLSGGLGKLV---LNSDTLSKD-PFNTKNDQLVGWDKQKTNQ----VQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQS--DPTNDIRIVEPTITKTVIPFTQKP----NIPFDNDFF------------SIPLAYTXXXXXXXXXXXXXXXXPCVTILVRRQK---YRNKKCKEALR-RHFQEEHARFLTLSQQQFKDSVNN----PTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCIA-PNFSFINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMIL--KFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIGIK 3021
            GN +  +EK +  DPAI+A  ++  PY +    +C+ +++YGC ++  ++ Y M  G    S ++L+D  YDG +   YLSGGLG+LV      D    D   N K  + VGW     +     V+ITF F   +NF+ + +  + + +K+V++FS+ ++     G  ++ + V    I +  V+     V + L +  G+F+K+ L F + WI+L  + F+S     N+    EP     ++  T  P      P   D              ++P           + +++ I    + +L+       YRN++ K AL    F ++H       Q++ +D        P  +  + +  + P ++  +   S    S+  ++   +C  D+ + I   + +F    P +      +    N    T  T     GA+     +N   +AR    ++ +     PI   P + +A+ E    S+P   P+      P  ++K  S  T   PE M +           +   E L  ++ +   +FG +HI E     D+    ++ F+    NT                      +  +K L   ++  L+ EF +E KR+  L  +    +L    E+ P+    +V E+    D   YLQ+  + E S +H    AK +S   L+YMA+QIA GMKHLE +  VHRDL+ RN L+ +    +K+SDL      +++DY                                  ++    LPIRWM W+++L G  ++KSDV+SF VT WE+LT  R+QP+ EL + +++ N+      D+R  ILP+P N  K+  + +  C H N+  RPSF EI MFLQ K++  K
Sbjct:   72 GNNNPYSEKEQVFDPAIVATKIRFIPYTSHMRMVCIRVELYGCPWIEGLVSYSMPQGIKRGSEVDLSDRTYDGREEAGYLSGGLGQLVDGQKGPDNFRLDVSGNGKGYEWVGWRNDTPSMLGRPVEITFEFDYSRNFTAIHLHMNNYFTKDVQVFSYAKVYLGAGGNQFNGEPVHFSYIPDL-VLEQARDVTIKLHSRAGRFLKLQLYFAARWIMLSEVIFESVISEWNNTDDEEPRNKSAIVLATGSPYQNNEGPLQRDEVKATFNKEENNDNALPDKSKEPESRQFVGLVIGILTTVIVMLLAAIMFIFYRNRRLKAALAPSTFYDQHGDLKVSVQEEGEDKGPICPPLPAQYHPATYTTTTPQLHKTITDYSGCSRSINHANRTPDCIRDRFKVILLRSLNFYIPMPYVRCRFDVKLHRRNQRIIT-ITLWDHGGAAGYNTAIN---LARPIPPVQEYPSNPPPIPPPPEKYYASTEICKNSLPPLPPSPTPSTPPPMSAKASSSMTSYSPEDMLTEEEDEVPECILDFPREKLNIVENLGCGYFGDVHICEV----DRFPGYDEVFR----NT-------------------SSDLVIVKSLRPGSSDALRIEFQQEAKRLARLADRNVARLLGASLEDDPM---CIVLENGEYGDLNQYLQSH-IAETSTVH---TAKTLSFGTLVYMATQIASGMKHLEEMDFVHRDLATRNCLV-SRGYTVKVSDLGSGRNAYAADY--------------------------------FRVDGRPPLPIRWMAWESMLMGRHTSKSDVWSFAVTLWEILTFAREQPFEELPDHRIVENATYFYQEDDRRIILPLPKNCPKDIYELMRECWHRNDVDRPSFREIHMFLQRKNLSYK 892          

Query: 1783 DEPSHRS---IPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARI-LPVPNNYSKEFSDFITHCMHFNESTRPSFVEI-DMFLQHKS 3009
            DEP + S   +P Y  A +  Q    +S   S+T V  P      G+L           E L + + +    FG +H+ E     D + E                   G+E E I        + ++K L ++ T+  +N+F KEI+ +  L     P I++      E  PL    +++E+    D   +L    L++  +   +T +  IS S LI MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +  DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE LTLC++QPY +L+++QVI N+  +   D+  ++ LP P          +  C   N   RPSF  I    LQH++
Sbjct:  502 DEPPNNSTEEVPHYAEADIVNQQEAVSSPGYSVTAVPVPLPPGRDGAL------EEFPREKLTFKEKLGEGQFGEVHLCEANGMQDFMKEDED----------------GVENEPI--------LVAVKTLREDATKNTRNDFLKEIRIMSRLRD---PNIIRLLAVCVESDPL---CMITEYMENGDLNKFLSRHKLQDSGEEQKDT-SSTISYSTLIRMATQIASGMKYLSSLNFVHRDLATRNCLV-GTNYTIKIADFGMSRNLYRGDY--------------------------------YRIQGRAVLPIRWMSWESILLGKFTMASDVWAFGVTLWETLTLCKEQPYSQLSDDQVIENTG-EFFRDQNKQVYLPRPACCPDAVHSLMQSCWRRNAKERPSFQHIHSTLLQHQA 849          

Query:   76 FLILISLELLFTATITNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIHDKR-RDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGS-------YLNLTDFNYDGDKSDSYLSGGLGKLV-----LNSDTLSKDPFNTKNDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQS 1098
            FL+++S  +    +  N   C   L     K+ D   + SS + E    ++ R      + AWCP+     K  ++FL IDL  ++ + ++ T+G    G  +  A SY I+Y R+    W  +  R   + I GNK+      + L+P IIAR+V+  P ++   T+C+ +++YGC+++  ++ Y    G        ++ L D  YDG   D  ++ GLG+L      L++ T S+          VGW      +  V++ F F + +NF+ + +  +   +  V+ F      F  +          +   D T     F  V V L + +   +K    F+  W++   I FQS
Sbjct:    9 FLVILSGAV---RSQVNPGVCRYPLGMTGGKIQDEDISASSQWSESTAARYGRLDFDDGDGAWCPDVVAEAKSLKEFLQIDLRTLHFVTLVGTQGRHADGMGNEFAQSYRIKYSRDG-VRWVSWHDRNGGQVIDGNKNPYEVVLKDLEPPIIARFVRFMPVSDPSMTVCMRVELYGCEWLDGLVSYSAPVGQEMTFQNLHVYLNDTVYDG-TVDHSMTEGLGQLTDGSWGLDNFTQSQVYGVWPGYDYVGWTNASFPSGSVEMVFEFDRVRNFTSMKVHCNNMYTSGVRAFQQAVCYFRSESDWEARPVSFKPEADNTNTSARF--VTVALGHRMASAIKCRFAFSDAWMMFSEIAFQS 360          

Query: 1792 SHRSIPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDL-SYANVALEN-----LKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETG-------AKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARI-LPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFL 2997
            +   +P Y  A +          LQ +T  N     +++ +L  DL S  ++A+E      L + + +    FG +H+ E     +  M+ +  F   +  T+                     + ++K+L  +  +  +N+F KEIK +  L     P I++          V      L     Y++N  L +    H   G       A  +S +NL +MA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE LT C++QPY +L++EQVI N+  +   D+R +I LP P          +  C + N   RPSF EI   L
Sbjct:  526 AQEGVPHYAEADIV--------NLQGVTGGN----TYAVPALTMDLLSGKDIAVEEFPRKLLTFKEKLGEGQFGEVHLCE-AEDMEDYMDEDFSFDVSDNQTV---------------------LVAVKMLRADANKNARNDFLKEIKIMSRLKD---PNIIRL-------LAVCMSSDPLCMITEYMENGDLNQFLSRHEPEGMIALLSNAPTVSYNNLHHMATQIASGMKYLSSLNFVHRDLATRNCLV-GKNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETLTFCKEQPYSQLSDEQVIENTG-EFFRDQRRQIYLPQPPLCPDPAYKLMLSCWNRNAKERPSFQEIHQVL 863          

Query:  121 TNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGS---------YLNLTDFNYDGDKSDSYLSGGLGKLV-----LNSDTLSKDPFNTKNDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSD 1101
             N   C   L  +  ++ D   + SS + +    K+ R      + AWCP      +  ++FL IDL  ++ + ++ T+G    G  +  A +Y I+Y R+  S W  +R+R  ++ I+GN++      + L P IIAR+V+  P  +    +C+ +++YGC+++  ++ Y    G          YLN  D  YDG  S S ++ GLG+L      L+  T S           VGW  +      V+I F F + +NF+ + +  +   S+ VK F  +   F  +             +D+      F  V V L N++   +K    F+ +W++   I FQSD
Sbjct:   33 VNPSVCRSPLGMSGGQILDEDISASSQWSDSTAAKYGRLDCEEGDGAWCPEIPGEPENMKEFLQIDLRSLHFITLVGTQGRHAGGIGNEFAQTYKIKYSRDG-SRWISWRNRHGKQVIEGNRNAYDVVLQDLQPPIIARFVRFMPVIDHSMNVCMRVELYGCEWLDGLVSYNAPLGQKMILHSQPIYLN--DSVYDGAMSYS-MTEGLGQLTDGMCGLDDFTFSHVYNVWPGYDYVGWTNESFPNGYVEIMFEFDRTRNFTTMKVHCNNMFSQRVKTFQKVVCYFRSESDWEPTPVSFSPVVDDVNPSARF--VTVSLNNHMASAIKCQYYFSDMWMMFSEITFQSD 373          

Query: 1924 DLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSN 2856
            D+S A    E L + + +    FG +H+                  C E   L + L  G     + +Q     + ++K L  + T   +N+F KEIK +  LN    P I++         PL    +V+E+    D   +L    L+  S L +      +S ++L++MA QIA GMK+L  L  VHRDL+ RN L ++  L IKISD  ++   +SSDY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+ TLC +QPY  LT+EQVI NS 
Sbjct:  521 DISVAEFPRERLIFREKLGEGQFGEVHL------------------C-EAEGLAEFLGEGAP---LPEQDGRSVLVAVKQLRADATSNARNDFLKEIKIMSRLND---PNIIRLLCVCVRSDPL---CMVTEYMENGDLNMFLSQRELE--STLTHANNIPSVSMADLLHMAVQIASGMKYLASLNFVHRDLATRNCL-LDRQLTIKISDFGMSRNLYSSDYY--------------------------------RIQGRAVLPIRWMAWESILLGKFTTASDVWAFGVTLWEIFTLCTEQPYSLLTDEQVIENSG 773          

Query:  136 CSDKLLENKNKVPDSAFTESSYKEEFKG-KWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLN--------LTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPF-NTKNDQL------VGW--DKQKTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKR--VLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSD----PTNDIRIVEPTITKTVIP 1155
            C   L     ++ +   T SS   E  G ++ R +    + AWCP  ++      +L +DL  +  + ++ T+G      G   A  Y ++Y R+ +  W  +R+R   + IKGN                     +  YA++         ++GC +   +  Y   +G  +         L D  YDG      L GGLG+  L    + +D F  T+  QL      +GW  D      V++ F+F + +NF+ + +  +   S+ VK+FS +   F    ++  E    V    +D+      + +VP  L    G   +    F   W++   I F S     PT   R++   +++T  P
Sbjct:   22 CRYPLGMEDGRIKNDDITASSQWYETTGPQYGRLNKEEGDGAWCPAGQLQPSDVQYLQVDLRQLTFVTVVATQGRYARSSGNEFARKYRLDYSRDGH-RWISWRNRYGSEIIKGN---------------------VNTYASV---------VFGCPWQDGLTAYSAPEGQTMMAPGFPNTLLNDSTYDGVLERRKLLGGLGQ--LTDGVIGQDDFVQTRQYQLWPGYDYLGWRNDSLGPGYVEMEFQFDRQRNFTSMKVHCNNMFSRGVKVFSSVSCVFKPHLISEWEAEPVVFSTVLDDRNPSARYVTVP--LLQRSGTATRCRFFFADTWMMFSEISFHSAMNPVPTPWSRVMTTPLSETESP 352          

Query: 2146 ISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYL-QNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMND---------DLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            + ++K+L  + ++  +N+F KE+K +  L     P I++         PL    +V+E+    D   YL Q   L +   LH       IS   LI MASQIA GMK L  L  VHRDL+ RN L+  +         +  IKI+D  ++   ++ DY                                  I    VLPIRWM W+ +L G F+  SDV++FGVT WE+L++C++QPY  +T+EQVI N+        R   L  P    +   + +  C + +   RPSF  +  FL   ++
Sbjct:  727 LVAVKILRPDASKNARNDFLKEVKILSRLKD---PNIIRLLGVCVSSDPL---CMVTEYMESGDLNQYLSQRVLLDKTGPLH---NTPTISYPALISMASQIASGMKFLASLNFVHRDLATRNCLVGGERGDGEDRMGERHIKIADFGMSRNLYAGDYY--------------------------------RIQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSHMTDEQVIDNAGEFFRDHGRQIYLTRPAVCPQGLYELMLSCWNRDCKLRPSFTHMHSFLAEDAM 989          

Query:  214 KGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLT-------DFNYDGDKSDSYLSGGLGKL---VLNSDTL--SKDPFNTKNDQLVGWDKQKTNQ--VQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSID-ETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDP 1104
            + K  R ST   + AWCP   +     +FL ++L  ++ L ++ T+G     HG   A SY + Y R+    W  ++ R  Q+ I GN++      + L P IIAR V+ YP A+   ++CL +++YGC +   +  Y    G  ++L+       D  YDG      L GGLG+L   VL  D    SK+         VGW ++   Q  V I F F + + F  + + ++   ++ V++FS +  +F    + +  +  L+  +  E     +  SV + L     + ++    F   W+++  I F S+P
Sbjct:   81 EAKHGRLSTGEGDGAWCPAGAVFPSGSEFLQVNLHKLHFLSLVGTQGRHADGHGREFARSYRLRYSRDGR-QWITWKDRWGQEVISGNENTYDVVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAYAAPMGHVMHLSGSPIYLNDSIYDGSIEAGTLFGGLGQLCDGVLGGDDFMESKELRVWPGYDYVGWSREALGQPTVDIEFHFEKTRIFHVMQVHSNNRHTQGVRVFSEVVCEFKASLLDHWTEPALKLRVPLEDLKDPSSRSVDLPLGGRPAQILRCHFAFADRWLLISEISFNSEP 393          

Query: 2146 ISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-----EETPLGDSVVVSEHTALDDAYSYL-QNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMND---------DLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            + ++K+L  + ++  +N+F KE+K +  L     P I++         PL    +V+E+    D   YL Q   L +   LH       IS   LI MASQIA GMK L  L  VHRDL+ RN L+  +         +  IKI+D  ++   ++ DY                                  I    VLPIRWM W+ +L G F+  SDV++FGVT WE+L++C++QPY  +T+EQVI N+        R   L  P    +   + +  C + +   RPSF  +  FL   ++
Sbjct:  670 LVAVKILRPDASKNARNDFLKEVKILSRLKD---PNIIRLLGVCVSSDPL---CMVTEYMESGDLNQYLSQRVLLDKTGPLH---NTPTISYPALISMASQIASGMKFLASLNFVHRDLATRNCLVGGERGDGEDRMGERHIKIADFGMSRNLYAGDYY--------------------------------RIQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSHMTDEQVIDNAGEFFRDHGRQIYLTRPAVCPQGLYELMLSCWNRDCKLRPSFTHMHSFLAEDAM 932          

Query:  214 KGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLT-------DFNYDGDKSDSYLSGGLGKL---VLNSDTL--SKDPFNTKNDQLVGWDKQKTNQ--VQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSID-ETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDP 1104
            + K  R ST   + AWCP   +     +FL ++L  ++ L ++ T+G     HG   A SY + Y R+    W  ++ R  Q+ I GN++      + L P IIAR V+ YP A+   ++CL +++YGC +   +  Y    G  ++L+       D  YDG      L GGLG+L   VL  D    SK+         VGW ++   Q  V I F F + + F  + + ++   ++ V++FS +  +F    + +  +  L+  +  E     +  SV + L     + ++    F   W+++  I F S+P
Sbjct:   62 EAKHGRLSTGEGDGAWCPAGAVFPSGSEFLQVNLHKLHFLSLVGTQGRHADGHGREFARSYRLRYSRDGR-QWITWKDRWGQEVISGNENTYDVVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAYAAPMGHVMHLSGSPIYLNDSIYDGSIEAGTLFGGLGQLCDGVLGGDDFMESKELRVWPGYDYVGWSREALGQPTVDIEFHFEKTRIFHVMQVHSNNRHTQGVRVFSEVVCEFKASLLDHWTEPALKLRVPLEDLKDPSSRSVDLPLGGRPAQILRCHFAFADRWLLISEISFNSEP 374          

Query: 2191 KNEFFKEIKRILSLNHKCFPMILKFEETPLGDS--VVVSEHTALDDAYSYLQNFTLKELSDLH--YETGAKVISQ----SNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSN 2856
            +N+F KEIK +  L     P I++     + D    +++E+    D   +L       + D+   +    K+IS       L+YMASQI  GM +L  L  VHRDL+ RN L+  +   IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+LTLCR+QPY  LT+EQVI N+ 
Sbjct:    8 RNDFLKEIKIMSRLKD---PNIVRLLGVCMRDDPLSMITEYMVNGDLNQFLSRLP-SAIGDIFIFFAPHQKLISVPPKLDKLVYMASQIVSGMAYLSSLNFVHRDLATRNCLV-GEHHTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMAWESILLGKFTPASDVWAFGVTLWEMLTLCREQPYGALTDEQVIENTG 200          

Query: 2152 SIKVLSKNTTQKLKNEFFKEIKRILSLN--HKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEI 2985
            +IK +++  T + + EF  E   + S N  H    + +  +  P+   +V+ E     D  SYL++       D   +      S   ++ MA +IA GM +L   K VHRDL+ RN ++  +D  +KI D  +  + + +DY            K    L                      LP+RWM  ++L  G F+  SDV+SFGV  WE+ T   +QPY  L+NEQV     L+ + D    +L +P    +   + I  C  +N   RP+F+EI
Sbjct:   93 AIKTVNETATMRERYEFLNEASVMKSFNCHHVVRLLGVVSQAQPI---LVIMELMTRGDLKSYLRSLR----PDAEKKPTRPPSSLPEMLQMAGEIADGMAYLNAKKFVHRDLAARNCMVA-EDFTVKIGDFGMTRDIYETDY----------YRKGGKGL----------------------LPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATQA-EQPYQGLSNEQV-----LKFVMD--GGLLVLPPACPERLQELIRKCWQYNPRMRPTFLEI 324          

Query: 2152 SIKVLSKNTTQKLKNEFFKEIKRILSLN--HKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFT-----LKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEI 2985
            +IK +++  T + + EF  E   + S N  H    + +  +  P+   +V+ E     D  SYL++         E   L  +      S   ++ MA +IA GM +L   K VHRDL+ RN ++  +D  +KI D  +  + + +DY            K    L                      LP+RWM  ++L  G F+  SDV+SFGV  WE+ T   +QPY  L+NEQV     L+ + D    +L +P    +   + I  C  +N   RP+F+EI
Sbjct:   45 AIKTVNETATMRERYEFLNEASVMKSFNCHHVVRLLGVVSQAQPI---LVIMELMTRGDLKSYLRSLRPDAEDFTETIVLEKKPTRPPSSLPEMLQMAGEIADGMAYLNAKKFVHRDLAARNCMV-AEDFTVKIGDFGMTRDIYETDY----------YRKGGKGL----------------------LPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATQA-EQPYQGLSNEQV-----LKFVMD--GGLLVLPPACPERLQELIRKCWQYNPRMRPTFLEI 285          

Query: 2137 EKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHY----------ETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEI 2985
            E  + + K L K+ +   + +F++E + + +L H+    I++F         V  E   L   + Y++N  L +   L            +   +++SQ+ ++ M SQIA GM +L     VHRDL+ RN L+    L++KI D  ++ + +S+DY                                  +    +LPIRWMP ++++   F+  SDV+S GV  WE+ T   KQP+++L+N +V I+   Q       R+L  P +   E  + +  C H     R    +I
Sbjct:  103 EPMLVAAKTL-KDLSDGARKDFYREAELLTNLQHE---HIVRFYG-------VCVEGEPLIMVFEYMKNGDLNKFLRLRGPDAVFMGDAPQAEPRLLSQAQMLNMGSQIAAGMAYLASQHFVHRDLATRNCLV-GAGLVVKIGDFGMSRDVYSTDYY--------------------------------RVGGHTMLPIRWMPPESIMYRKFTADSDVWSLGVVLWEIFTY-GKQPWYQLSNTEV-IDCICQ------GRVLERPRSCPMEVYELMLGCWHREPQHRLGIKDI 343          

Query: 2386 AKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQ 3000
              V+   +LI MA Q+A GM +LE    +HRDL+ RN+L+  D+L  K++D  +A      +Y+      A    K                            P++W   +A     F+ KSDV+SFG+  +E++T   K PY  +TN +V     L+ L  E    +P P N  ++F   + +C H  E+ RPSF+++D  L+
Sbjct:  212 GGVLKMCHLINMAVQVASGMAYLEAQNYIHRDLAARNILV-GDNLTCKVADFGLARVIKDDEYI------AREGGK---------------------------FPVKWTAPEAANYSRFTIKSDVWSFGILLYEIVTY-GKVPYAGMTNAEV-----LEEL--EHGYRMPCPTNCPRDFYSIMYNCWHKEEACRPSFLQLDHQLE 374          

Query: 2422 ASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIGIK*DIKTTRFYKL 3054
             +Q   G+K+L    ++HRD+   N+L+  D+  +K++D  ++                       SS + L                     + WM  + L     S  SD++S G T  E+LT  +  PYH LT+  +           E     P P+++S+   DF++ C   N   RP+    D  L+H  I    ++K  +  K 
Sbjct:  127 VTQTLLGLKYLHGEGVIHRDIKAANILLSADNT-VKLADFGVST-------------------IVNSSALTLAGT------------------LNWMAPEILGNRGASTLSDIWSLGATVVEMLT--KNPPYHNLTDANIY-------YAVENDTYYP-PSSFSEPLKDFLSKCFVKNMYKRPT---ADQLLKHVWINSTENVKVDKLNKF 286          

Query: 2140 KQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSV---VVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELL 2793
            KQ++ IK++ ++T +K  ++  K  + I +L H   P I+  EE  L +S    +V E  +  + Y Y+Q                + + +S+   + +Q+  G+ ++ Y  LVHRDL   N+L+   + L+ I+D    NE F  + ++ T                       SC +P      +V+  +   ++A        K+DV+S GV  + +L
Sbjct:   75 KQVA-IKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEV-LQNSKYIGIVLEFVSGGEFYKYIQR--------------KRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLV-ITDFGFVNEFFEDNELMKT-----------------------SCGSPCYAAPELVVSTKA--YEA-------RKADVWSCGVILYAML 246          

Query: 2131 FPEKQISSIKVLSKNTTQKLKNEFFKEIK---RILSLNHKCFPMILKFEETPLGDSV---VVSEHTALDDAYSYLQN-FTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELL 2793
            FP KQ++ IK++ +++   + N++ KE+K    I +L H   P I+K EE  L +S    +V E+    + Y Y+Q    LKE+               N   + SQ+  G+ ++    LVHRDL   N+L+  ++ L+ I+D    NE  S + ++ T                       SC +P      +V  I   P++A        K+D++S GV  + +L
Sbjct:   73 FP-KQVA-IKLIKRDS---ISNDYRKEVKIYREINALKHLSHPNIVKLEEV-LQNSRYIGIVLEYACGGEFYKYIQKKRRLKEM---------------NACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLV-ITDFGFVNEFCSRNELMKT-----------------------SCGSPCYAAPELV--ISAEPYEA-------RKADIWSCGVILYAIL 246          

Query: 2161 VLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF-EETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDE--------RARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHK 3006
            +L     + +K +FFKE+K +  + H+    +L   ++ P+    ++ E+    D   +L+    +EL+  +     KV  Q+ L+YMA Q+A GMK++   + VHRDL+ RN L+      +KI+D  ++   +S  Y                                  I   ++LPIRWM  + +LQG F++ SDV++FGVT WE+LTL  + PY +LT+E+VI N  L     +        R  I P P+ Y+K     +  C     S RP F +I  FL+++
Sbjct:    1 MLKAGVDKNIKQDFFKEVKIMAGVRHENVVRLLGVCKDDPM---CMIVEYMENGDLNQFLKQ---RELASGNSADPNKVTYQA-LLYMALQLAAGMKYIASHQFVHRDLATRNCLV-GHSFTVKIADFGMSRHLYSKHYY--------------------------------RIQGRVILPIRWMAPECILQGKFTSASDVWAFGVTLWEILTLAAEYPYGDLTDEKVIENVQLMFFRPKSDAITFLSRPEICP-PDVYAK-----MRSCWAIEPSARPDFHDIHSFLENR 245          

Query: 2146 ISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF--EETPLGDSVVVSEHTALDDAYSYLQN---FTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQV 2841
            I ++K L +  + ++K  F +E+  +  L+H     +L    EE P G   ++ E  +  D   Y++    ++L+E          K ++Q +L+ ++ Q++ GM+HL+ ++ VHRDL+ RN L+  D L++KI+D  ++ + ++SDY                                 ++    V+PIRWMP +ALL G F+ +SDVYSFGV  WE+      QPY+  TNE+V
Sbjct:    3 IVAVKTLKQGCSNEMKTSFLQEVTLMAVLHHPNIVELLAVSTEEEPYG---MIFEFMSQGDLNQYMRKRGPYSLEE---------EKSLTQEDLLSISLQVSSGMEHLQSMRFVHRDLATRNCLV-GDGLVVKIADFGMSRDVYASDY--------------------------------YKVEGQAVMPIRWMPPEALLYGRFTVESDVYSFGVLLWEVYAFAL-QPYYGYTNEEV 193          

Query: 1990 FGSIHIG-EWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKE--IKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEI 2985
            F S++I  EW  P ++I +  ++     +  + +      E  +I    P+ +++ +K +S+N + + + EF +E  I +    NH    + +  +  P   ++VV E     D    L+NF      ++  E+     +   ++ MA +IA GM +L   K VHRDL+ RN ++ N +L +KI D  +  + + +DY            K    L                      LP+RWM  ++L  G F++ SDV+SFGV  WE+ TL   QPY   +NE+V     L+ + D    ++P P++      D +T C  F+   RP+F+ I
Sbjct:    2 FPSVYIADEWEVPREKI-KLIRELGNGSFGMVYEG-----EATDIVPNKPKCKVA-VKTVSENASIRDRIEFLQEASIMKAFQCNHVVRLLGVVSDGQP---TLVVMELMDNGD----LKNFLRSHRPEVTMESDEPPPTLQQMLQMAGEIADGMAYLAARKFVHRDLAARNCMV-NANLTVKIGDFGMTRDIYETDY----------YRKGGKGL----------------------LPVRWMAPESLKDGVFTSPSDVWSFGVVMWEMATLA-SQPYPGKSNEEV-----LKYVVD--GGVMPKPDDCPDRLFDLMTLCWQFSPKARPTFLSI 281          

Query: 2266 EETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQV 2841
            EE P G   ++ E     D   YL++    E S       AK     +L+ +A Q+A GM+++  L+ VHRDL+ RN L+   D+++KI+D  ++ + + SDY   +  T                                +LPIRW+  +A L G F+ KSDVYS+GV  WE+ T    QPY+  TN++V
Sbjct:   32 EEEPYG---MIFEFMGEGDLNHYLRSAKPAESSAYKGPDDAK-----DLVGIAEQVAAGMEYVASLRFVHRDLATRNCLV-GTDMVVKIADFGMSRDVYGSDYYKMSRET--------------------------------MLPIRWLAPEAFLYGKFTVKSDVYSYGVLLWEIFTFGL-QPYYGYTNKEV 181          

Query: 2188 LKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHY------ETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSF 2976
            ++ +F +E++ ++++ H                S VVS      D+  +   F   E  DL        + G   ++ S+ + M S I  GM +L   K VH+DL+ RN ++  D L +KI  L ++ + ++++Y  F +                                 I++P+RWMP +A+   +F+ KSDV+SFGV  WE+ +L  + PY + ++E+V     L+ + D+    LP P+N     ++ +  C   N + RP+F
Sbjct:   51 VREDFTRELESLVNMEH----------------SNVVSLLGVCRDSEPFYMIFECFEKGDLKQFLLSCNDNGRSTLTSSHKLTMCSNIVSGMSYLAANKFVHKDLAARNCMVTKD-LQVKIGFLNLSYDLYNAEYYRFNN---------------------------------ILIPLRWMPSEAIFHDDFTEKSDVWSFGVLAWEIYSL-GQIPYTDRSDEEV-----LKCVKDDLR--LPKPDNCPDNMANVMKKCWEPNPNDRPNF 261          

Query: 1861 LQSITTVND---PEIMFSLGSLFNDLSYANVALEN-----LKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQ--ISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETG-------AKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEI 2985
            LQ +T  N    P +   L      LS  +VA+E      L + + +    FG +H+ E         E  ++F   EY               +F   PE Q  + ++K+L  +     +N+F KEIK +  L     P I++          V      L     Y++N  L +    H   G          +S SNL YMA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+L  C++QPY +LT+EQVI N+       +R   LP P   S      +  C   N   RPSF EI
Sbjct:  534 LQGVTGSNTYAIPAVTLDL------LSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCE--------AEGMQEFLHEEY---------------LFD-IPEDQPVLVAVKMLRSDANGNARNDFLKEIKIMSRLKD---PNIIRL-------LAVCIYSNPLCMITEYMENGDLNQFLSRHEPEGQLALLSNTATVSFSNLCYMATQIASGMKYLSSLNFVHRDLATRNCLV-GKNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWEILNFCKEQPYSQLTDEQVIENTGEFFRDQKRQIYLPQPVLCSDSLYKIMLTCWRRNAKERPSFQEI 852          

Query:  121 TNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLTDFN-------YDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKND-------QLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSD-PTNDIRIVEPTI 1137
             N   C   L  +  ++ D   + SS + E    +  R      + AWCP   +  D  ++F+ IDL  ++ + ++ T+G    G  +  A  Y+I+Y R+  S W  +R+R  ++ I+GN++        LDP IIAR+V+  P  +    +C+ +++YGCK++  ++ Y    G  + L  F        YDG  +   ++ GLG+  L+   +  D F   +          VGW+ +   +  V+I F F + +NF+ + +  +   S+++K+F  +   F  D             +DE      F  + V+L N +   +K    F   W++   I FQSD    +  +V PTI
Sbjct:   25 VNPDVCRYPLGMSGGQIRDEDISASSQWSESTAARHGRLDCEEGDGAWCPETTVEPDNLKEFIQIDLNLLHFITLVGTQGRHAGGMGNEFAQMYMIKYSRDG-SRWISWRNRQGKQVIEGNRNTYDTVLRDLDPPIIARFVRFMPVTDHSMNVCMRVELYGCKWLDGLVSYNAPAGEQMKLPAFPVFFNDSVYDGAIT-HMMTEGLGQ--LSDGVMGLDDFTQSHVYQAWPGYDYVGWNNESFPSGFVEIMFEFDRPRNFTTMKVHCNNMFSQHIKIFRQVVCYFRSDSDWESTVLSFSPVVDENDPSARF--ITVELTNRMANAIKCQFYFKDAWMLFSEITFQSDRAMYNTTLVPPTI 378          

Query: 1861 LQSITTVND---PEIMFSLGSLFNDLSYANVALEN-----LKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQ--ISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETG-------AKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEI 2985
            LQ +T  N    P +   L      LS  +VA+E      L + + +    FG +H+ E         E  ++F   EY               +F   PE Q  + ++K+L  +     +N+F KEIK +  L     P I++          V      L     Y++N  L +    H   G          +S SNL YMA+QIA GMK+L  L  VHRDL+ RN L+   +  IKI+D  ++   +S DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+L  C++QPY +LT+EQVI N+       +R   LP P   S      +  C   N   RPSF EI
Sbjct:  534 LQGVTGSNTYAIPAVTLDL------LSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCE--------AEGMQEFLHEEY---------------LFD-IPEDQPVLVAVKMLRSDANGNARNDFLKEIKIMSRLKD---PNIIRL-------LAVCIYSNPLCMITEYMENGDLNQFLSRHEPEGQLALLSNTATVSFSNLCYMATQIASGMKYLSSLNFVHRDLATRNCLV-GKNYTIKIADFGMSRNLYSGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWEILNFCKEQPYSQLTDEQVIENTGEFFRDQKRQIYLPQPVLCSDSLYKIMLTCWRRNAKERPSFQEI 852          

Query:  121 TNTKSCSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIH-DKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLTDFN-------YDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKND-------QLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSD-PTNDIRIVEPTI 1137
             N   C   L  +  ++ D   + SS + E    +  R      + AWCP   +  D  ++F+ IDL  ++ + ++ T+G    G  +  A  Y+I+Y R+  S W  +R+R  ++ I+GN++        LDP IIAR+V+  P  +    +C+ +++YGCK++  ++ Y    G  + L  F        YDG  +   ++ GLG+  L+   +  D F   +          VGW+ +   +  V+I F F + +NF+ + +  +   S+++K+F  +   F  D             +DE      F  + V+L N +   +K    F   W++   I FQSD    +  +V PTI
Sbjct:   25 VNPDVCRYPLGMSGGQIRDEDISASSQWSESTAARHGRLDCEEGDGAWCPETTVEPDNLKEFIQIDLNLLHFITLVGTQGRHAGGMGNEFAQMYMIKYSRDG-SRWISWRNRQGKQVIEGNRNTYDTVLRDLDPPIIARFVRFMPVTDHSMNVCMRVELYGCKWLDGLVSYNAPAGEQMKLPAFPVFFNDSVYDGAIT-HMMTEGLGQ--LSDGVMGLDDFTQSHVYQAWPGYDYVGWNNESFPSGFVEIMFEFDRPRNFTTMKVHCNNMFSQHIKIFRQVVCYFRSDSDWESTVLSFSPVVDENDPSARF--ITVELTNRMANAIKCQFYFKDAWMLFSEITFQSDRAMYNTTLVPPTI 378          

Query: 1921 NDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKEL---SDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKE-FSDFITHCMHFNESTRPSFVEIDMFLQ 3000
             D S      E L + + +    FG +H+ E         E  + F       L + L+ G  +E++        + ++K L ++  +  +N+F KEI+ +  L     P I++          V  +   L     Y++N  L +    S + +  GA  +S + LI MA QIA GMK+L  L  VHRDL+ RN L+   +  I+I+D  ++   +  DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+LTLC++QPY +L++EQVI N+        +   LP P       ++D +  C   N   RPSF EI   LQ
Sbjct:  541 TDSSLREFPREKLSFKEKLGEGQFGEVHLCE--------AEGMQDF-------LDEDLSVGEISESLL-------LVAVKTLREDANKNARNDFLKEIRIMSRLRD---PNIVRL-------LAVCVDTDPLWMITEYMENGDLNQFLSRSKIFFLFGA--LSYTKLINMAVQIASGMKYLSSLNFVHRDLATRNCLV-GKNYTIRIADFGMSRNLYKGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTMASDVWAFGVTLWEILTLCKEQPYSQLSDEQVIENTGEFFRDKGKQVYLPKPPCCPDSVYNDLMLSCWRRNAKQRPSFQEIHAQLQ 837          

Query:   76 FLILISLELLFTATITN-TKSCSDKLLENKNKVPDSAFTESSY-KEEFKGKWARESTSPTEMAWCPN--NKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLTD----FN---YDGDKSDSYLSGGLGKLVLNS----DTLSKDPFNT-KNDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQS 1098
            FL+   +E L+ +  +   + C   L     ++ D   + SSY  E    K+ R      + AWCP+  ++ H   +++L +DL  ++ + ++ T+G    G  +  A  Y I+Y R+  SNW  ++ R  Q+ I+GN++      + L+P IIAR+V+  P  +    +C+ +++YGC+++  ++ Y + DG  +   D    FN   YDG    + L+ GLG+L   +    D L    +        VGW  +      V++ F F   +NF+ + +  S   S+ V++F  +   F  D          + + D  RV      V V L +   K +K    F+ +W++   + FQS
Sbjct:   12 FLLHTHIEYLWISVASCFPEVCRYPLGMTGGQIQDEDISASSYWSESTAAKFGRLDIGGGDGAWCPDIMSEPH-GLKEYLQVDLRSLHFITLVGTQGRHADGMGNEFAQRYRIKYSRDG-SNWVSWQDRKGQQVIEGNRNAYDVVLKDLEPPIIARYVRFMPVTDHSMIVCMRVELYGCEWLDGLVSYSIPDGHQMIYRDLEVSFNDSVYDG----ASLTKGLGQLTDGTWGLDDFLHSQIYGVWPGYDYVGWSNRTFPKGYVEMIFDFDHVRNFTSMKVHTSNMFSRGVRVFRQVTCFFWSDSEWEPGPITFRPTPD--RVSQRARFVTVTLGDRTAKTIKCRFHFSDVWMLFSEVAFQS 364          

Query: 1951 ENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF--EETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDL---HYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSN 2856
            E L + + +    FG +H+ E         E  + F       L + L+ G  +E++        + ++K L ++  +  +N+F KEI+ +  L       +L    +  PL    +++E+    D   +L N  LKE  D      E G   IS + LI MA QIA GMK+L  L  VHRDL+ RN L+   +  I+I+D  ++   +  DY                                  I    VLPIRWM W+++L G F+  SDV++FGVT WE+LTLC++QPY +L++EQVI N+ 
Sbjct:  552 EKLSFKEKLGEGQFGEVHLCE--------AEGMQDF-------LDEDLSVGEISESLL-------LVAVKTLREDANKNARNDFLKEIRIMSRLRDPNIVRLLAVCVDTDPL---WMITEYMENGDLNQFLCNLRLKEAPDEDKPEQEEGEDSISYTKLINMAVQIASGMKYLSSLNFVHRDLATRNCLV-GKNYTIRIADFGMSRNLYKGDYY--------------------------------RIQGRAVLPIRWMSWESILLGKFTMASDVWAFGVTLWEILTLCKEQPYSQLSDEQVIENTG 800          

Query:   85 LISLELLFTATI---TNTKSCSDKLLENKNKVPDSAFTESSY-KEEFKGKWARESTSPTEMAWCPN--NKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFIS--ASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLTD----FN---YDGDKSDSYLSGGLGKLVLNS----DTLSKDPFNT-KNDQLVGWDKQK--TNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQS 1098
            +I L +L  AT+    N + C   L     ++ D   + SSY  E    K+ R      + AWCP+  ++ H   +++L +DL  ++ + ++ T+G    G  +  A  Y I+Y R+  SNW  ++ R  Q+ I+GN++      + L+P IIAR+V+  P  +    +C+ +++YGC+++  ++ Y + DG  +   D    FN   YDG  ++  L+ GLG+L   +    D L    +        VGW  +      V++ F F   +NF+ + +  S   S+ V++F  +   F  D          + + D  RV      V V L +   K +K    F+ +W++   + FQS
Sbjct:    5 VIRLFVLLAATVEAQVNPEVCRYPLGMTGGQIQDEDISASSYWSESTAAKFGRLDIGGGDGAWCPDIMSEPH-GLKEYLQVDLRSLHFITLVGTQGRHADGMGNEFAQRYRIKYSRDG-SNWVSWQDRKGQQVIEGNRNAYDVVLKDLEPPIIARYVRFMPVTDHSMIVCMRVELYGCEWLDGLVSYSIPDGHQMIYRDLEVSFNDSVYDGASAEG-LTKGLGQLTDGTWGLDDFLHSQIYGVWPGYDYVGWSNRTFPKGYVEMIFDFDHVRNFTSMKVHTSNMFSRGVRVFRQVTCFFWSDSEWEPGPITFRPTPD--RVSQRARFVTVTLGDRTAKTIKCRFHFSDVWMLFSEVAFQS 359          

Query: 2146 ISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKF--EETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMND----------DLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSI 3012
            + ++K+L  + ++  +N+F KE+K +  L       +L       PL    +V+E+    D   YL +  L + +   +   A  IS   LI +ASQIA GMK L  L  VHRDL+ RN L+  D          +  IKI+D  ++   ++ DY                                  I    VLPIRWM W+ +L G F+  SDV++FGVT WE+L++C++QPY  LT+EQVI N+        R   L  P    +   + +  C + +   RPSF  I  FL   ++
Sbjct:  488 LVAVKILRPDASKNARNDFLKEVKILSRLKDPNIIQLLGVCVSSDPL---CMVTEYMECGDLNQYLSHRVLLDKTGPSHN--APTISYPALISIASQIASGMKFLSSLNFVHRDLATRNCLVGGDRGENGEDRGGERQIKIADFGMSRNLYAGDYY--------------------------------RIQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSNLTDEQVIDNAGEFFRDQGRQVYLGKPAVCPQGLYELMLSCWNRDCKLRPSFAHIHSFLTEDAM 751          

Query:  136 CSDKLLENKNKVPDSAFTESS-YKEEFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKG--LSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLN-------LTDFNYDGDKSDSYLSGGLGKL---VLNSD--TLSKDPFNTKNDQLVGWDKQKTNQ--VQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQF 915
            C   L      +PDS  + SS + +  + K  R ST   + AWCP   +     ++L IDL  ++ L ++ T+G     HG     SY + Y R+    W  ++ R  Q+ + GN +      + L P I+AR V+ YP A+   ++CL +++YGC +   +  Y    G  +N       L D  YDG        GGLG+L   VL  D  T +K+         VGW ++   Q  V I F F + + F  + + ++   ++ V++FS ++  F
Sbjct:   25 CRYALGMEAGTIPDSDISASSAWSDSTEAKHGRLSTGEGDGAWCPLGPVFPSGSEYLQIDLHKLHFLALVGTQGRHADGHGQEFTRSYRLRYSRDG-VKWITWKDRWGQEVVSGNTNTHEVVLKDLGPPIVARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAYTSPVGHVMNLPGLPVYLNDSIYDGSTEQRMQFGGLGQLCDGVLGGDDFTQTKELRVWPGYDYVGWSREALGQGSVDIEFHFEKPRLFINMQVHSNNRHTQGVRVFSKVECLF 300          

Query:   70 MNFLILISLELLFTATITNTKSCSDKLLENKNKVPDSAFTESSYKEEFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQLVGWDKQKTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQSDPTNDIRIVEPTITKTVIPFTQKPNIPFDNDFFSIPLAYTXXXXXXXXXXXXXXXXPCVTILVRRQKYRNKKCKEALRRHFQEEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCIAPNFSFINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIGIK 3021
            MNFLILISLELLFTATITNTKSCSDKLLENKNKVPDSAFTESSYKEEFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFISASSYIIEYKREANS+WFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQLVGWDKQKTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILK+IEFQSDPTNDIRIVEPTITK VIPFTQKPNIPFDNDFFSIPLAYTLVIVISILIIMLLIGIPCVTILVRRQKYRNKKCKEALRRHFQEEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCIAPNFSFINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIGIK
Sbjct:    1 MNFLILISLELLFTATITNTKSCSDKLLENKNKVPDSAFTESSYKEEFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFISASSYIIEYKREANSSWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGSYLNLTDFNYDGDKSDSYLSGGLGKLVLNSDTLSKDPFNTKNDQLVGWDKQKTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKHIEFQSDPTNDIRIVEPTITKAVIPFTQKPNIPFDNDFFSIPLAYTLVIVISILIIMLLIGIPCVTILVRRQKYRNKKCKEALRRHFQEEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCIAPNFSFINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIGIK 984          

Query:   70 MNFLILISLELLFTATITNTKSCSDKLLENKNKVPDSAFTESSYKEEFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGS-YLN---------LTDFNYDGD-KSDSYLSGGLGKLVLNSDTLSKD--PFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQS---DPTNDIRIVEP---------TITKTVIPFTQKPNIPFDNDFF---SIPLAYTXXXXXXXXXXXXXXXXPCVTILVR-RQKYRNKKCKEALRRHFQ-EEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCI--APNFSFINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIGIK 3021
            MNF+ ++S++    A   +  SC  KLL N+  VPD AF  SS++ +++ K+AR+S S  E AWCP  K+H+  ++F+ IDLG IY+LKMIMTKGLSRHG+ SAS Y I+YK E    W  YR+  + KKI GNKDHLTEK+    P+I+ RW++IYP ++  E ICL LQ+YGC+Y + ++EY+M DGS Y N          TD +YDG       L  GLGKL  + D    D  PFN  ++  VGW +   K + + I FRF   + F  + + A+ + + +V L   I+I FS DG  ++  + +  +I E R   +   + +DLK   G+FV I+L F S WI+++ I F S   +  +++   +P         T+TK ++    K N     D F   SI L    ++ I            C+  +++ ++K R +K K+A+    Q EE+ R LTL  Q  K   N    + V+N    L  +N +               TE   N  +   I  A N+ F N   + +    +  S+ ND  AT + S+  N  + + Y      +  SQ                                MY           R + +  I+T N PE   S       L+++      LK I+ IS   +G I +    RP               Y+         ++  NI  +F +  I  ++ + +++   +K  F +E+  +  +NHK     +  ++     S VV+E+T+L D ++ L++     LS L        I QS  +Y+A Q++  + +LEYL LVHRD++CRN+L+ +  L IK+SDLAIA  +F S Y     P              L SN   + QN + I S  ++PIRWMPW+ + + +FS KSDVY FGV  WEL   C++ PY  L+N Q+ +N +      +  + L  P + ++E  D I  C+      RP+F EI +F   K+ G K
Sbjct:    1 MNFITILSIK---NALTEDKDSCYQKLLTNRTNVPDDAFIVSSFEIDYEAKYARDS-SLIEKAWCPRYKVHNSTKEFITIDLGSIYVLKMIMTKGLSRHGYKSASYYYIKYKIEEKQEWIRYRNVSEFKKISGNKDHLTEKFNLFTPSIVTRWIRIYPISSHPEMICLNLQLYGCRYTNNVIEYQMVDGSLYYNQEKKIKEPYFTDQSYDGVLLHTGMLKSGLGKLT-DHDYEKNDNNPFNMSSNPFVGWSRSDFKFDHIHIVFRFINNRKFVNVSLRAANYWTASVALPKRIEIAFSSDGRRFERGKSINHAIKEDRENFDTRWIVIDLKKRTGRFVSINLHFQSQWIMVREILFSSESLESVSNVGTTQPSEFTSKSYSTLTKIIV----KSNAITITDIFLSSSISLGILFLLAI------------CLICIIKWKRKSRIRKYKKAMHLQSQDEEYNRILTLQHQNMK---NQTLYYPVAN----LSTLNTKF-------------HTEERPNKFRQMIIPEAYNYWFYNDFCLDSRSNMDTHSLYND--ATKYFSMEKNIQTDLSYLDVRGPLGNSQ--------------------------------MY-----------RMNLINFISTTNYPEFS-SFHEFVKQLNFS-----ELKTIENISNNSYGRIDVA---RP------------SIGYSPYEMEPYKDMDNSNIEGKFSD-TILCVRKIKQDSPVNVKENFHQELDNLNQINHKNLITFVVVQDKCDLASYVVNEYTSLMDIFTLLES-----LSILQSNNDLISIEQSQFLYIAVQLSDALSYLEYLGLVHRDIACRNILVTSPHLYIKLSDLAIAQNRFRSQYWEVNKPQL------------LDSN---NKQNEV-IKSSHLIPIRWMPWEVISKKDFSTKSDVYGFGVCMWELFNYCQQLPYESLSNYQIFVNKSSLNSNIQPHQSLKFPQSTARETIDIIEQCLVDEALQRPTFKEIHIFFSKKNSGYK 889          

Query:   70 MNFLILISLELLFTATITNTKSCSDKLLENKNKVPDSAFTESSYKEEFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGS-YLN---------LTDFNYDGD-KSDSYLSGGLGKLVLNSDTLSKD--PFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQS---DPTNDIRIVEP---------TITKTVIPFTQKPNIPFDNDFF---SIPLAYTXXXXXXXXXXXXXXXXPCVTILVR-RQKYRNKKCKEALRRHFQ-EEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCI--APNFSFINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIGIK 3021
            MNF+ ++S++    A   +  SC  KLL N+  VPD AF  SS++ +++ K+AR+S S  E AWCP  K+H+  ++F+ IDLG IY+LKMIMTKGLSRHG+ SAS Y I+YK E    W  YR+  + KKI GNKDHLTEK+    P+I+ RW++IYP ++  E ICL LQ+YGC+Y + ++EY+M DGS Y N          TD +YDG       L  GLGKL  + D    D  PFN  ++  VGW +   K + + I FRF   + F  + + A+ + + +V L   I+I FS DG  ++  + +  +I E R   +   + +DLK   G+FV I+L F S WI+++ I F S   +  +++   +P         T+TK ++    K N     D F   SI L    ++ I            C+  +++ ++K R +K K+A+    Q EE+ R LTL  Q  K   N    + V+N    L  +N +               TE   N  +   I  A N+ F N   + +    +  S+ ND  AT + S+  N  + + Y      +  SQ                                MY           R + +  I+T N PE   S       L+++      LK I+ IS   +G I +    RP               Y+         ++  NI  +F +  I  ++ + +++   +K  F +E+  +  +NHK     +  ++     S VV+E+T+L D ++ L++     LS L        I QS  +Y+A Q++  + +LEYL LVHRD++CRN+L+ +  L IK+SDLAIA  +F S Y     P              L SN   + QN + I S  ++PIRWMPW+ + + +FS KSDVY FGV  WEL   C++ PY  L+N Q+ +N +      +  + L  P + ++E  D I  C+      RP+F EI +F   K+ G K
Sbjct:    5 MNFITILSIK---NALTEDKDSCYQKLLTNRTNVPDDAFIVSSFEIDYEAKYARDS-SLIEKAWCPRYKVHNSTKEFITIDLGSIYVLKMIMTKGLSRHGYKSASYYYIKYKIEEKQEWIRYRNVSEFKKISGNKDHLTEKFNLFTPSIVTRWIRIYPISSHPEMICLNLQLYGCRYTNNVIEYQMVDGSLYYNQEKKIKEPYFTDQSYDGVLLHTGMLKSGLGKLT-DHDYEKNDNNPFNMSSNPFVGWSRSDFKFDHIHIVFRFINNRKFVNVSLRAANYWTASVALPKRIEIAFSSDGRRFERGKSINHAIKEDRENFDTRWIVIDLKKRTGRFVSINLHFQSQWIMVREILFSSESLESVSNVGTTQPSEFTSKSYSTLTKIIV----KSNAITITDIFLSSSISLGILFLLAI------------CLICIIKWKRKSRIRKYKKAMHLQSQDEEYNRILTLQHQNMK---NQTLYYPVAN----LSTLNTKF-------------HTEERPNKFRQMIIPEAYNYWFYNDFCLDSRSNMDTHSLYND--ATKYFSMEKNIQTDLSYLDVRGPLGNSQ--------------------------------MY-----------RMNLINFISTTNYPEFS-SFHEFVKQLNFS-----ELKTIENISNNSYGRIDVA---RP------------SIGYSPYEMEPYKDMDNSNIEGKFSD-TILCVRKIKQDSPVNVKENFHQELDNLNQINHKNLITFVVVQDKCDLASYVVNEYTSLMDIFTLLES-----LSILQSNNDLISIEQSQFLYIAVQLSDALSYLEYLGLVHRDIACRNILVTSPHLYIKLSDLAIAQNRFRSQYWEVNKPQL------------LDSN---NKQNEV-IKSSHLIPIRWMPWEVISKKDFSTKSDVYGFGVCMWELFNYCQQLPYESLSNYQIFVNKSSLNSNIQPHQSLKFPQSTARETIDIIEQCLVDEALQRPTFKEIHIFFSKKNSGYK 893          

Query:   70 MNFLILISLELLFTATITNTKSCSDKLLENKNKVPDSAFTESSYKEEFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGS-YLN---------LTDFNYDGD-KSDSYLSGGLGKLVLNSDTLSKD--PFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQS---DPTNDIRIVEP---------TITKTVIPFTQKPNIPFDNDFF---SIPLAYTXXXXXXXXXXXXXXXXPCVTILVR-RQKYRNKKCKEALRRHFQ-EEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCI--APNFSFINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIGIK 3021
            MNF+ ++S++    A   +  SC  KLL N+  VPD AF  SS++ +++ K+AR+S S  E AWCP  K+H+  ++F+ IDLG IY+LKMIMTKGLSRHG+ SAS Y I+YK E    W  YR+     KI GNKDHLTEK+    P+I+ RW++IYP ++  E ICL LQ+YGC+Y + ++EY+M DGS Y N          TD +YDG       L  GLGKL  + D    D  PFN  ++  VGW +   K + + I FRF   + F  + + A+ + + +V L   I+I FS DG  ++  + +  +I E R   +   + +DLK   G+FV I+L F S WI+++ I F S   +  +++   +P         T+TK ++    K N     D F   SI L    ++ I            C+  +++ ++K R +K K+A+    Q EE+ R LTL  Q  K   N    + V+N    L  +N +               TE   N  +   I  A N+ F N   + +    +  S+ ND  AT + S+  N  + + Y      +  SQ                                MY           R + +  I+T N PE   S       L+++      LK I+ IS   +G I +    RP               Y+         ++  NI  +F +  I  ++ + +++   +K  F +E+  +  +NHK     +  ++     S VV+E+T+L D ++ L++     LS L        I QS  +Y+A Q++  + +LEYL LVHRD++CRN+L+ +  L IK+SDLAIA  +F S Y     P              L SN   + QN + I S  ++PIRWMPW+ + + +FS KSDVY FGV  WEL   C++ PY  L+N Q+ +N +      +  + L  P + ++E  D I  C+      RP+F EI +F   K+ G K
Sbjct:    1 MNFITILSIK---NALTEDKDSCYQKLLTNRTNVPDDAFIVSSFEIDYEAKYARDS-SLIEKAWCPRYKVHNSTKEFITIDLGSIYVLKMIMTKGLSRHGYKSASYYYIKYKIEEKQEWIRYRN-----KISGNKDHLTEKFNLFTPSIVTRWIRIYPISSHPEMICLNLQLYGCRYTNNVIEYQMVDGSLYYNQEKKIKEPYFTDQSYDGVLLHTGMLKSGLGKLT-DHDYEKNDNNPFNMSSNPFVGWSRSDFKFDHIHIVFRFINNRKFVNVSLRAANYWTASVALPKRIEIAFSSDGRRFERGKSINHAIKEDRENFDTRWIVIDLKKRTGRFVSINLHFQSQWIMVREILFSSESLESVSNVGTTQPSEFTSKSYSTLTKIIV----KSNAITITDIFLSSSISLGILFLLAI------------CLICIIKWKRKSRIRKYKKAMHLQSQDEEYNRILTLQHQNMK---NQTLYYPVAN----LSTLNTKF-------------HTEERPNKFRQMIIPEAYNYWFYNDFCLDSRSNMDTHSLYND--ATKYFSMEKNIQTDLSYLDVRGPLGNSQ--------------------------------MY-----------RMNLINFISTTNYPEFS-SFHEFVKQLNFS-----ELKTIENISNNSYGRIDVA---RP------------SIGYSPYEMEPYKDMDNSNIEGKFSD-TILCVRKIKQDSPVNVKENFHQELDNLNQINHKNLITFVVVQDKCDLASYVVNEYTSLMDIFTLLES-----LSILQSNNDLISIEQSQFLYIAVQLSDALSYLEYLGLVHRDIACRNILVTSPHLYIKLSDLAIAQNRFRSQYWEVNKPQL------------LDSN---NKQNEV-IKSSHLIPIRWMPWEVISKKDFSTKSDVYGFGVCMWELFNYCQQLPYESLSNYQIFVNKSSLNSNIQPHQSLKFPQSTARETIDIIEQCLVDEALQRPTFKEIHIFFSKKNSGYK 884          

Query:   70 MNFLILISLELLFTATITNTKSCSDKLLENKNKVPDSAFTESSYKEEFKGKWARESTSPTEMAWCPNNKIHDKRRDFLMIDLGDIYILKMIMTKGLSRHGFISASSYIIEYKREANSNWFEYRSRGKQKKIKGNKDHLTEKYESLDPAIIARWVKIYPYANIEETICLVLQIYGCKYMSQIMEYRMDDGS-YLN---------LTDFNYDGD-KSDSYLSGGLGKLVLNSDTLSKD--PFNTKNDQLVGWDKQ--KTNQVQITFRFAQFQNFSKLLIEASIFPSKNVKLFSHIQIQFSYDGVTYDEKRVLQQSIDETRVINNFHSVPVDLKNNVGKFVKISLTFNSIWIILKYIEFQS---DPTNDIRIVEP---------TITKTVIPFTQKPNIPFDNDFF---SIPLAYTXXXXXXXXXXXXXXXXPCVTILVR-RQKYRNKKCKEALRRHFQ-EEHARFLTLSQQQFKDSVNNPTLFTVSNFNPSLPNINGRMMQESSIYTSLAGSDTESNCNSDKPQCI--APNFSFINTCPIINPLTSNRGSISNDYSATSFTSLGSNGASYVPYYVNNAQMARSQINLKSHYDMVNPISSNPNESFANDEPSHRSIPMYGPARVSIQGPLRNSKLQSITTVNDPEIMFSLGSLFNDLSYANVALENLKYIKTISRCHFGSIHIGEWLRPHDQIMETNKKFQCHEYNTLRQSLTTGIETENIFQQFPEKQISSIKVLSKNTTQKLKNEFFKEIKRILSLNHKCFPMILKFEETPLGDSVVVSEHTALDDAYSYLQNFTLKELSDLHYETGAKVISQSNLIYMASQIACGMKHLEYLKLVHRDLSCRNVLIMNDDLLIKISDLAIANEKFSSDYVIFTDPTANHIHKSTSSLIQLQSNPIHSCQNPIEINSVIVLPIRWMPWQALLQGNFSNKSDVYSFGVTFWELLTLCRKQPYHELTNEQVIINSNLQALGDERARILPVPNNYSKEFSDFITHCMHFNESTRPSFVEIDMFLQHKSIGIK 3021
            MNF+ ++S++    A   +  SC  KLL N+  VPD AF  SS++ +++ K+AR+S S  E AWCP  K+H+  ++F+ IDLG IY+LKMIMTKGLSRHG+ SAS Y I+YK E    W  YR+     KI GNKDHLTEK+    P+I+ RW++IYP ++  E ICL LQ+YGC+Y + ++EY+M DGS Y N          TD +YDG       L  GLGKL  + D    D  PFN  ++  VGW +   K + + I FRF   + F  + + A+ + + +V L   I+I FS DG  ++  + +  +I E R   +   + +DLK   G+FV I+L F S WI+++ I F S   +  +++   +P         T+TK ++    K N     D F   SI L    ++ I            C+  +++ ++K R +K K+A+    Q EE+ R LTL  Q  K   N    + V+N    L  +N +               TE   N  +   I  A N+ F N   + +    +  S+ ND  AT + S+  N  + + Y      +  SQ                                MY           R + +  I+T N PE   S       L+++      LK I+ IS   +G I +    RP               Y+         ++  NI  +F +  I  ++ + +++   +K  F +E+  +  +NHK     +  ++     S VV+E+T+L D ++ L++     LS L        I QS  +Y+A Q++  + +LEYL LVHRD++CRN+L+ +  L IK+SDLAIA  +F S Y     P              L SN   + QN + I S  ++PIRWMPW+ + + +FS KSDVY FGV  WEL   C++ PY  L+N Q+ +N +      +  + L  P + ++E  D I  C+      RP+F EI +F   K+ G K
Sbjct:    5 MNFITILSIK---NALTEDKDSCYQKLLTNRTNVPDDAFIVSSFEIDYEAKYARDS-SLIEKAWCPRYKVHNSTKEFITIDLGSIYVLKMIMTKGLSRHGYKSASYYYIKYKIEEKQEWIRYRN-----KISGNKDHLTEKFNLFTPSIVTRWIRIYPISSHPEMICLNLQLYGCRYTNNVIEYQMVDGSLYYNQEKKIKEPYFTDQSYDGVLLHTGMLKSGLGKLT-DHDYEKNDNNPFNMSSNPFVGWSRSDFKFDHIHIVFRFINNRKFVNVSLRAANYWTASVALPKRIEIAFSSDGRRFERGKSINHAIKEDRENFDTRWIVIDLKKRTGRFVSINLHFQSQWIMVREILFSSESLESVSNVGTTQPSEFTSKSYSTLTKIIV----KSNAITITDIFLSSSISLGILFLLAI------------CLICIIKWKRKSRIRKYKKAMHLQSQDEEYNRILTLQHQNMK---NQTLYYPVAN----LSTLNTKF-------------HTEERPNKFRQMIIPEAYNYWFYNDFCLDSRSNMDTHSLYND--ATKYFSMEKNIQTDLSYLDVRGPLGNSQ--------------------------------MY-----------RMNLINFISTTNYPEFS-SFHEFVKQLNFS-----ELKTIENISNNSYGRIDVA---RP------------SIGYSPYEMEPYKDMDNSNIEGKFSD-TILCVRKIKQDSPVNVKENFHQELDNLNQINHKNLITFVVVQDKCDLASYVVNEYTSLMDIFTLLES-----LSILQSNNDLISIEQSQFLYIAVQLSDALSYLEYLGLVHRDIACRNILVTSPHLYIKLSDLAIAQNRFRSQYWEVNKPQL------------LDSN---NKQNEV-IKSSHLIPIRWMPWEVISKKDFSTKSDVYGFGVCMWELFNYCQQLPYESLSNYQIFVNKSSLNSNIQPHQSLKFPQSTARETIDIIEQCLVDEALQRPTFKEIHIFFSKKNSGYK 888