cdc7-like protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008000 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of cdc7-like protein vs. Ensembl Human
Match: CDC7 (cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745]) HSP 1 Score: 143.665 bits (361), Expect = 1.005e-36 Identity = 70/156 (44.87%), Postives = 101/156 (64.74%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAH 650
E V Q S++ F+I DKIGEG+F++V+ ++ +E ALK IP P RI EL+ L GG+ NV+ + + FR DH+ + MP+++H F+D + E+R+Y+ NL ALK +H+ I+HRDVKP+NFLY+RR KK+ LVDFGLA
Sbjct: 49 EAVPQLSNV---FKIEDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQ 201 HSP 2 Score: 76.2554 bits (186), Expect = 3.961e-14 Identity = 48/184 (26.09%), Postives = 83/184 (45.11%), Query Frame = 3
Query: 696 HSDFGNEKIAIK------SIDSQNNMKRQDTGTLKSRLSDTSIL---SESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKI 1220
HS +E A+K ++D + + +++ +++++ + S +C C C C +R R GT G+R PEV + QTTA+D W+ G+I L+G+YPF+K DDL ++ + AAK + I+ + K +P Q +RK CE++
Sbjct: 295 HSSISHESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVCSICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKTFGKSILCS-KEVP------------AQDLRKLCERL 465
BLAST of cdc7-like protein vs. Ensembl Human
Match: CDC7 (cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745]) HSP 1 Score: 143.665 bits (361), Expect = 1.005e-36 Identity = 70/156 (44.87%), Postives = 101/156 (64.74%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAH 650
E V Q S++ F+I DKIGEG+F++V+ ++ +E ALK IP P RI EL+ L GG+ NV+ + + FR DH+ + MP+++H F+D + E+R+Y+ NL ALK +H+ I+HRDVKP+NFLY+RR KK+ LVDFGLA
Sbjct: 49 EAVPQLSNV---FKIEDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQ 201 HSP 2 Score: 76.2554 bits (186), Expect = 3.961e-14 Identity = 48/184 (26.09%), Postives = 83/184 (45.11%), Query Frame = 3
Query: 696 HSDFGNEKIAIK------SIDSQNNMKRQDTGTLKSRLSDTSIL---SESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKI 1220
HS +E A+K ++D + + +++ +++++ + S +C C C C +R R GT G+R PEV + QTTA+D W+ G+I L+G+YPF+K DDL ++ + AAK + I+ + K +P Q +RK CE++
Sbjct: 295 HSSISHESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVCSICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKTFGKSILCS-KEVP------------AQDLRKLCERL 465
BLAST of cdc7-like protein vs. Ensembl Human
Match: CAMK1G (calcium/calmodulin dependent protein kinase IG [Source:HGNC Symbol;Acc:HGNC:14585]) HSP 1 Score: 85.5001 bits (210), Expect = 2.798e-18 Identity = 63/235 (26.81%), Postives = 115/235 (48.94%), Query Frame = 3
Query: 186 YVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFT--IPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRD---YLRNLLVALKHVHENKIIHRDVKPNNFLY--DRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKR--------QDTGTLKSRL-SDTSILSESNQIEASCI 842
+ KQ ++I F ++ +G G+F+ VF V+ + + ++FALK P +ENE+ +LKKI +N++ L + H +++M V + D L + +D ++ +L A+K++HEN I+HRD+KP N LY K + DFGL+ E +G + + + + S+D+ ++MK+ T+ L S + LS+ + A+C+
Sbjct: 12 WKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQR---LTGKLFALKCIKKSPAFRDSSLENEIAVLKKIK-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACGTPGY---------VGSVDTPHSMKKRSLSFSRRSRRATMSLSLHSGMTFLSQPRTLFATCL 233
BLAST of cdc7-like protein vs. Ensembl Human
Match: CDC7 (cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745]) HSP 1 Score: 80.8777 bits (198), Expect = 2.158e-17 Identity = 42/112 (37.50%), Postives = 66/112 (58.93%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDY 518
E V Q S++ F+I DKIGEG+F++V+ ++ +E ALK IP P RI EL+ L GG+ NV+ + + FR DH+ + MP+++H F+D + E+R+Y
Sbjct: 49 EAVPQLSNV---FKIEDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREY 157
BLAST of cdc7-like protein vs. Ensembl Human
Match: CAMK1G (calcium/calmodulin dependent protein kinase IG [Source:HGNC Symbol;Acc:HGNC:14585]) HSP 1 Score: 84.7297 bits (208), Expect = 5.927e-17 Identity = 52/167 (31.14%), Postives = 89/167 (53.29%), Query Frame = 3
Query: 186 YVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKF--TIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRD---YLRNLLVALKHVHENKIIHRDVKPNNFLY--DRRRKKFTLVDFGLAHSEVHG 665
+ KQ ++I F ++ +G G+F+ VF V+ + + ++FALK P +ENE+ +LKKI +N++ L + H +++M V + D L + +D ++ +L A+K++HEN I+HRD+KP N LY K + DFGL+ E +G
Sbjct: 12 WKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQR---LTGKLFALKCIKKSPAFRDSSLENEIAVLKKIK-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG 174
BLAST of cdc7-like protein vs. Ensembl Celegans
Match: cdc-7 (Cell Division Cycle related [Source:UniProtKB/TrEMBL;Acc:O01493]) HSP 1 Score: 104.375 bits (259), Expect = 4.031e-24 Identity = 93/384 (24.22%), Postives = 154/384 (40.10%), Query Frame = 3
Query: 237 IGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFID--YYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQ-VRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLP-----LIGAFN---DWIKSRCQFIRKNCEKITKLIKDNSDKNCIY------------GNHAEFDDSAYDLLSKLLE 1319
IGEGSF V + + + I A++ I + EL +L ++GG N++KL F + +++ H + ++ D++ Y RNLL A+ ++H N +HRD+K +NFLY + ++F LVDFGLA ++D N S + ++ + C C + C CR +P + GT G R PE+ ++D ++ GI++ ++ K+PFF D+ + L + L E ++ A R+ ++ K P LI D ++ C R+ C K +NS C GN E DLL + LE
Sbjct: 34 IGEGSFGTVISATCRTTQEKRAIKAIR---RIEKMSMLSIELELLSELGGHFNIVKLFEFFHFNGSVAIVLEHFPHCTATELLFHSKRDLSFALSYFRNLLYAVAYLHHNGYVHRDIKLSNFLYSPQTQRFRLVDFGLA----------------------------TVDRSKN-----------ECSRSHAVAAMERDPECCSCKGTSSPCMFCRGKPKRENYNVVGTPGVRAPELLFGIGLCHPSIDIFSCGIVLLSLVSVKHPFFMPKDETENIMHLAFLLGSETIEKMAHSEGLRVTLSEKLPPADYYHLILCLRFGFDHVRRHCSSSRQPCTICQKRSFNNSMGVCFCRKNYETDMFSTGGNETELMTIYVDLLYRTLE 375
BLAST of cdc7-like protein vs. Ensembl Celegans
Match: dapk-1 (Death-associated protein kinase dapk-1 [Source:UniProtKB/Swiss-Prot;Acc:O44997]) HSP 1 Score: 78.9518 bits (193), Expect = 2.942e-15 Identity = 46/157 (29.30%), Postives = 84/157 (53.50%), Query Frame = 3
Query: 213 DNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKF--------TIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYL---LMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRR-KKFTLVDFGLA 647
D +EI ++G G FA V +VR +K E +A KF + + + IE E+R+L+KI G NV++LH + + +++ V + D+ +D E +++ +L+A++H+H I+H D+KP N + +R + ++DFGL+
Sbjct: 26 DVYEIETELGSGQFAVVRRVRDRKT---GEKYAAKFIKKRRYATSRRGVTRQNIEREVRVLQKIRGNSNVVELHAVYETASDVIIVLELVSGGELFDHVCAKECLDEVEAAAFIKQILLAVRHLHSLHIVHLDIKPENVMLKQRGDSQIKIIDFGLS 179
BLAST of cdc7-like protein vs. Ensembl Celegans
Match: rskn-1 (Putative ribosomal protein S6 kinase alpha-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21734]) HSP 1 Score: 73.559 bits (179), Expect = 1.152e-13 Identity = 50/174 (28.74%), Postives = 92/174 (52.87%), Query Frame = 3
Query: 159 TTINIRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKF----TIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFV---DHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEV 659
T I+I V + +D FE++ +G+GSF VF VR + ++A+K T+ + D +R + E IL I ++KLH+AF+ + +++++ F+ D + ++ ++++ YL L +AL+H+H I++RD+KP N L D + DFGL+ +
Sbjct: 79 TEIDIGDVRKCGEKADPR-QFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHIS-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLD-ADGHIKVTDFGLSKEAI 249 HSP 2 Score: 53.5286 bits (127), Expect = 2.338e-7 Identity = 43/169 (25.44%), Postives = 80/169 (47.34%), Query Frame = 3
Query: 168 NIRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIE--NELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYL----LMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLY---DRRRKKFTLVDFGLA 647
++RSV K + D++EI++KIG G+ + V K + K K+ + I+ + E+ IL + + V+KL + + I+M+ + + +D + L E+ + NLL A++++H ++ HRD+ N L+ D +VDFG A
Sbjct: 432 SVRSVPTAKT-NPFTDDYEILEKIGNGAHSVVHKCQMKATRR-------KYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFA 592
BLAST of cdc7-like protein vs. Ensembl Celegans
Match: rskn-1 (Putative ribosomal protein S6 kinase alpha-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21734]) HSP 1 Score: 73.559 bits (179), Expect = 1.309e-13 Identity = 50/174 (28.74%), Postives = 92/174 (52.87%), Query Frame = 3
Query: 159 TTINIRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKF----TIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFV---DHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEV 659
T I+I V + +D FE++ +G+GSF VF VR + ++A+K T+ + D +R + E IL I ++KLH+AF+ + +++++ F+ D + ++ ++++ YL L +AL+H+H I++RD+KP N L D + DFGL+ +
Sbjct: 85 TEIDIGDVRKCGEKADPR-QFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHIS-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLD-ADGHIKVTDFGLSKEAI 255 HSP 2 Score: 53.5286 bits (127), Expect = 2.686e-7 Identity = 43/169 (25.44%), Postives = 80/169 (47.34%), Query Frame = 3
Query: 168 NIRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIE--NELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYL----LMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLY---DRRRKKFTLVDFGLA 647
++RSV K + D++EI++KIG G+ + V K + K K+ + I+ + E+ IL + + V+KL + + I+M+ + + +D + L E+ + NLL A++++H ++ HRD+ N L+ D +VDFG A
Sbjct: 438 SVRSVPTAKT-NPFTDDYEILEKIGNGAHSVVHKCQMKATRR-------KYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFA 598
BLAST of cdc7-like protein vs. Ensembl Celegans
Match: rskn-1 (Putative ribosomal protein S6 kinase alpha-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21734]) HSP 1 Score: 73.1738 bits (178), Expect = 1.613e-13 Identity = 50/174 (28.74%), Postives = 92/174 (52.87%), Query Frame = 3
Query: 159 TTINIRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKF----TIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFV---DHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEV 659
T I+I V + +D FE++ +G+GSF VF VR + ++A+K T+ + D +R + E IL I ++KLH+AF+ + +++++ F+ D + ++ ++++ YL L +AL+H+H I++RD+KP N L D + DFGL+ +
Sbjct: 46 TEIDIGDVRKCGEKADPR-QFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHIS-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLD-ADGHIKVTDFGLSKEAI 216 HSP 2 Score: 53.1434 bits (126), Expect = 3.544e-7 Identity = 43/169 (25.44%), Postives = 80/169 (47.34%), Query Frame = 3
Query: 168 NIRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIE--NELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYL----LMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLY---DRRRKKFTLVDFGLA 647
++RSV K + D++EI++KIG G+ + V K + K K+ + I+ + E+ IL + + V+KL + + I+M+ + + +D + L E+ + NLL A++++H ++ HRD+ N L+ D +VDFG A
Sbjct: 399 SVRSVPTAKT-NPFTDDYEILEKIGNGAHSVVHKCQMKATRR-------KYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFA 559
BLAST of cdc7-like protein vs. Ensembl Fly
Match: CG5790 (gene:FBgn0032677 transcript:FBtr0345614) HSP 1 Score: 194.512 bits (493), Expect = 7.533e-55 Identity = 142/470 (30.21%), Postives = 215/470 (45.74%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKK----IEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHS------------------------------DF------------GNEKIAIKSIDSQNNMKRQDTGTL------KSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPL--------IGAFNDWIKSRCQFIRKNCEKITKLIK--DNSDKNCIYGNHAE----------FDDSAYDLLSKLLEPKFHTRITCREALQHKFFN 1376
E + +IN F++ +IG G+F+ V ++ +E + FA+K P P+RI EL + +IGG +NVI ++ R D++ +MP++ H +F D Y ++ EIRDYLRNLL+AL+HVH+ +IHRDVKP+N LY+RR KF L DFGLA + D GS D S D+ G+ + A+ S ++ Q G L R +L+ + + N + + + + H R GT GYRPPEV +R+ +Q+TAVD WA G+IM L+G +PFFK D +I ++ A + R I++ K L + ++ Q + + T++ + + NC+ N F AYDLLS+LLE RIT EAL+H FF+
Sbjct: 133 ELQESIPEINKIFDVHCRIGSGTFSTVLLGTLQRERGLVETQRRRFAIKHHNPTNHPERILRELECMYRIGGVENVIGINCCIRYNDNVAFIMPYMTHDRFHDIYRSLNFPEIRDYLRNLLIALRHVHKFNVIHRDVKPSNILYNRRTGKFLLCDFGLA--QRIADDGSVVQSSDLSSREVFSILRDLENGRSVTLTDGNSAQAEAEDYMARRRMRALGGGGSVERAVTGPPSIQKLREQAGGHLTKKDVANQRADTMRLLNRLRLVSPNADPNNYVVSTNTSKKEMH--ASRAGTPGYRPPEVLLRYPKQSTAVDVWAAGVIMLSLLSGLHPFFKAPHDCGALAEIINLFGDMPVRKTAFLLDRLILLAQKVNTLDLRRVCMRFRHADFFLAPEIQRKYQRPDGTTEMCRSCEQPTFNCLCSNSGHNLERYDGLDIFPAVAYDLLSRLLEVNPQKRITAEEALKHPFFS 598
BLAST of cdc7-like protein vs. Ensembl Fly
Match: CG5790 (gene:FBgn0032677 transcript:FBtr0081050) HSP 1 Score: 194.512 bits (493), Expect = 7.533e-55 Identity = 142/470 (30.21%), Postives = 215/470 (45.74%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKK----IEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHS------------------------------DF------------GNEKIAIKSIDSQNNMKRQDTGTL------KSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPL--------IGAFNDWIKSRCQFIRKNCEKITKLIK--DNSDKNCIYGNHAE----------FDDSAYDLLSKLLEPKFHTRITCREALQHKFFN 1376
E + +IN F++ +IG G+F+ V ++ +E + FA+K P P+RI EL + +IGG +NVI ++ R D++ +MP++ H +F D Y ++ EIRDYLRNLL+AL+HVH+ +IHRDVKP+N LY+RR KF L DFGLA + D GS D S D+ G+ + A+ S ++ Q G L R +L+ + + N + + + + H R GT GYRPPEV +R+ +Q+TAVD WA G+IM L+G +PFFK D +I ++ A + R I++ K L + ++ Q + + T++ + + NC+ N F AYDLLS+LLE RIT EAL+H FF+
Sbjct: 133 ELQESIPEINKIFDVHCRIGSGTFSTVLLGTLQRERGLVETQRRRFAIKHHNPTNHPERILRELECMYRIGGVENVIGINCCIRYNDNVAFIMPYMTHDRFHDIYRSLNFPEIRDYLRNLLIALRHVHKFNVIHRDVKPSNILYNRRTGKFLLCDFGLA--QRIADDGSVVQSSDLSSREVFSILRDLENGRSVTLTDGNSAQAEAEDYMARRRMRALGGGGSVERAVTGPPSIQKLREQAGGHLTKKDVANQRADTMRLLNRLRLVSPNADPNNYVVSTNTSKKEMH--ASRAGTPGYRPPEVLLRYPKQSTAVDVWAAGVIMLSLLSGLHPFFKAPHDCGALAEIINLFGDMPVRKTAFLLDRLILLAQKVNTLDLRRVCMRFRHADFFLAPEIQRKYQRPDGTTEMCRSCEQPTFNCLCSNSGHNLERYDGLDIFPAVAYDLLSRLLEVNPQKRITAEEALKHPFFS 598
BLAST of cdc7-like protein vs. Ensembl Fly
Match: Cdc7 (gene:FBgn0028360 transcript:FBtr0343377) HSP 1 Score: 151.369 bits (381), Expect = 3.242e-39 Identity = 73/160 (45.62%), Postives = 104/160 (65.00%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVF----KVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAH 650
+ + + DI F++ +IG G+F+ V + S + L+ FA+K IP P RI EL+ + K+GGK+NV+ +H R +MPF+ H +F D+Y MD+ EIR Y+RNLLVAL+HVH+ +IHRDVKP+NFLY+RRR++F LVDFGLA
Sbjct: 114 DLLTRIPDIGKLFDVHSRIGNGTFSTVLLGTLRRESHLPDSLRRKFAIKHHIPTSHPDRIMKELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAHDRFQDFYTRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLAQ 273 HSP 2 Score: 102.834 bits (255), Expect = 5.292e-23 Identity = 63/201 (31.34%), Postives = 93/201 (46.27%), Query Frame = 3
Query: 837 CICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPL-----------IGAFNDW--------IKSRCQFIRKNCEK--ITKLIKDNSDKNCIYGNHAEFDDSAYDLLSKLLEPKFHTRITCREALQHKFFN 1376
C+C + C C + R GT GYRPPEV +++ +QTTAVD WA G+I ++ YPFFK +D ++ + ++ A + R I ++ + PL F+D + C+ R NC++ L +D+ + F SAYDLL +LLE H RIT EAL+H FF
Sbjct: 445 CVCFANPSVCLNCLMKKEVHASRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFGDQAIRKTALALDRMITLSQRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVDGSCEVCR-NCDQYFFNCLCEDSDYLTEPLDAYECFPPSAYDLLDRLLEINPHKRITAEEALKHPFFT 644
BLAST of cdc7-like protein vs. Ensembl Fly
Match: Cdc7 (gene:FBgn0028360 transcript:FBtr0070950) HSP 1 Score: 151.369 bits (381), Expect = 3.292e-39 Identity = 73/160 (45.62%), Postives = 104/160 (65.00%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVF----KVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAH 650
+ + + DI F++ +IG G+F+ V + S + L+ FA+K IP P RI EL+ + K+GGK+NV+ +H R +MPF+ H +F D+Y MD+ EIR Y+RNLLVAL+HVH+ +IHRDVKP+NFLY+RRR++F LVDFGLA
Sbjct: 115 DLLTRIPDIGKLFDVHSRIGNGTFSTVLLGTLRRESHLPDSLRRKFAIKHHIPTSHPDRIMKELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAHDRFQDFYTRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLAQ 274 HSP 2 Score: 102.834 bits (255), Expect = 5.205e-23 Identity = 63/201 (31.34%), Postives = 93/201 (46.27%), Query Frame = 3
Query: 837 CICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPL-----------IGAFNDW--------IKSRCQFIRKNCEK--ITKLIKDNSDKNCIYGNHAEFDDSAYDLLSKLLEPKFHTRITCREALQHKFFN 1376
C+C + C C + R GT GYRPPEV +++ +QTTAVD WA G+I ++ YPFFK +D ++ + ++ A + R I ++ + PL F+D + C+ R NC++ L +D+ + F SAYDLL +LLE H RIT EAL+H FF
Sbjct: 446 CVCFANPSVCLNCLMKKEVHASRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFGDQAIRKTALALDRMITLSQRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVDGSCEVCR-NCDQYFFNCLCEDSDYLTEPLDAYECFPPSAYDLLDRLLEINPHKRITAEEALKHPFFT 645
BLAST of cdc7-like protein vs. Ensembl Fly
Match: S6kII (gene:FBgn0262866 transcript:FBtr0333715) HSP 1 Score: 80.1073 bits (196), Expect = 1.596e-15 Identity = 52/171 (30.41%), Postives = 89/171 (52.05%), Query Frame = 3
Query: 183 EYVKQFSDIND--NFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKF----TIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFV---DHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGD 668
E +K+ D D FE++ +GEGSF VF VR + ++A+K T+ + D R NE +IL +G +++LH+AF+ +++++ F+ D + ++ +++ YL L +A+ H+H II+RD+KP N L D L DFGL+ + G
Sbjct: 185 EVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDRVRSTNERKILADVG-HAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLD-EHGHIALTDFGLSKQPLDGS 353 HSP 2 Score: 52.373 bits (124), Expect = 7.002e-7 Identity = 27/103 (26.21%), Postives = 52/103 (50.49%), Query Frame = 3
Query: 357 ELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLL---MDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRK---KFTLVDFGLA 647
E+ I+ + G N++ L+ + +++M + + +D L M +E LR + A+ ++HE+ ++HRD+KP+N +Y R+ L D G A
Sbjct: 618 EVEIMLRYGNHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYLHEHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFA 720
BLAST of cdc7-like protein vs. Ensembl Zebrafish
Match: cdc7 (cell division cycle 7 homolog (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-041114-113]) HSP 1 Score: 197.208 bits (500), Expect = 2.665e-57 Identity = 110/322 (34.16%), Postives = 174/322 (54.04%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTL--KSRLSDTSILSESNQIEASCICGNRLT--TCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVN 1136
E + Q S I F IIDKIGEG+F++V+ ++ + + +FALK IP P RI EL+ L GG +NV+ + + FR + H+ ++MP+++H F+D L+ ++R Y+ +LL ALKH+H+ IIHRD+KP NFL++R+++++ LVDFGLA D S E++ + I S + L K +L S + + C +T C+ C +R R GT G+R PEV + Q TA+D W+ G+I+ L+G+YPFFK +DDL ++ ++ AAK + I+ +
Sbjct: 37 EVLPQLSRI---FRIIDKIGEGTFSSVYLAEAQMTDSSRRLFALKHLIPTSHPVRIAAELQCLTVAGGTENVMGVTYCFRKEHHVVIVMPYMEHQTFVDIVGLLSFEDVRHYIYHLLKALKHIHKFGIIHRDIKPTNFLFNRQKREYALVDFGLAQGT--PDTQIELLKGLLSKPKKEEVIPRKIVSAKHRSVPVRAPLNQKQKLPAESQKPKPAAVNPLLTCNCYMTDRVCNICLSRKQQVAPRAGTPGFRAPEVLTKCPNQGTAIDMWSAGVILLSLLSGRYPFFKANDDLIALTQIMTIRGSKETIEAAKTFGKSIVCS 353
BLAST of cdc7-like protein vs. Ensembl Zebrafish
Match: cdc7 (cell division cycle 7 homolog (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-041114-113]) HSP 1 Score: 195.667 bits (496), Expect = 1.654e-56 Identity = 116/358 (32.40%), Postives = 184/358 (51.40%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHS------EVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMK--------------------------RQDTGTLKSRLSDTSILSESNQIEA--------SCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVN 1136
E + Q S I F IIDKIGEG+F++V+ ++ + + +FALK IP P RI EL+ L GG +NV+ + + FR + H+ ++MP+++H F+D L+ ++R Y+ +LL ALKH+H+ IIHRD+KP NFL++R+++++ LVDFGLA E+ +L D S FG KSI+S N+ K + + +++ L+ L +Q +C C C+ C +R R GT G+R PEV + Q TA+D W+ G+I+ L+G+YPFFK +DDL ++ ++ AAK + I+ +
Sbjct: 37 EVLPQLSRI---FRIIDKIGEGTFSSVYLAEAQMTDSSRRLFALKHLIPTSHPVRIAAELQCLTVAGGTENVMGVTYCFRKEHHVVIVMPYMEHQTFVDIVGLLSFEDVRHYIYHLLKALKHIHKFGIIHRDIKPTNFLFNRQKREYALVDFGLAQGTPDTQIELLKELMG-LDKAPRSVFGE-----KSINSTNSHKPGSDKVEGLLSKPKKEEVIPRKIVSAKHRSVPVRAPLNQKQKLPAESQKPKPAAVNPLLTCNCYMTDRVCNICLSRKQQVAPRAGTPGFRAPEVLTKCPNQGTAIDMWSAGVILLSLLSGRYPFFKANDDLIALTQIMTIRGSKETIEAAKTFGKSIVCS 385
BLAST of cdc7-like protein vs. Ensembl Zebrafish
Match: cdc7 (cell division cycle 7 homolog (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-041114-113]) HSP 1 Score: 147.902 bits (372), Expect = 1.497e-38 Identity = 73/190 (38.42%), Postives = 118/190 (62.11%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHS--EVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQ 746
E + Q S I F IIDKIGEG+F++V+ ++ + + +FALK IP P RI EL+ L GG +NV+ + + FR + H+ ++MP+++H F+D L+ ++R Y+ +LL ALKH+H+ IIHRD+KP NFL++R+++++ LVDFGLA + +L + H G+ K+ +S+ Q
Sbjct: 37 EVLPQLSRI---FRIIDKIGEGTFSSVYLAEAQMTDSSRRLFALKHLIPTSHPVRIAAELQCLTVAGGTENVMGVTYCFRKEHHVVIVMPYMEHQTFVDIVGLLSFEDVRHYIYHLLKALKHIHKFGIIHRDIKPTNFLFNRQKREYALVDFGLAQGTPDTQIELLKVVKSKGHKGGGSSKMVEESLGKQ 223 HSP 2 Score: 73.559 bits (179), Expect = 1.917e-13 Identity = 34/101 (33.66%), Postives = 53/101 (52.48%), Query Frame = 3
Query: 834 SCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVN 1136
+C C C+ C +R R GT G+R PEV + Q TA+D W+ G+I+ L+G+YPFFK +DDL ++ ++ AAK + I+ +
Sbjct: 343 TCNCYMTDRVCNICLSRKQQVAPRAGTPGFRAPEVLTKCPNQGTAIDMWSAGVILLSLLSGRYPFFKANDDLIALTQIMTIRGSKETIEAAKTFGKSIVCS 443
BLAST of cdc7-like protein vs. Ensembl Zebrafish
Match: camk1gb (calcium/calmodulin-dependent protein kinase IGb [Source:ZFIN;Acc:ZDB-GENE-040426-1694]) HSP 1 Score: 78.5666 bits (192), Expect = 3.063e-15 Identity = 55/176 (31.25%), Postives = 93/176 (52.84%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKR---IENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFID------YYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLY--DRRRKKFTLVDFGLAHSEVHGDLGS 677
E+ K +I D F+ +D +G G+F+ VF V+ +K ++FA+K KR +ENE+ +L+KI +NV+ L + + H +++M V + D Y MD + + +R +L A+ ++H N I+HRD+KP N LY K + DFGL+ E +G + +
Sbjct: 9 EWKKSTDNIQDVFDFMDVLGSGAFSEVFMVKERKT---GKLFAMKCVKK--KNKRDINLENEIAVLRKIK-HENVVCLEDFYESRTHYYLVMQLVSGGELFDRILDRGMYSEMDASSV---IRQVLEAVSYLHNNGIVHRDLKPENLLYYSPDENSKIMISDFGLSKMEDNGVMST 175
BLAST of cdc7-like protein vs. Ensembl Zebrafish
Match: si:ch73-60h1.1 (si:ch73-60h1.1 [Source:ZFIN;Acc:ZDB-GENE-140106-152]) HSP 1 Score: 78.1814 bits (191), Expect = 4.102e-15 Identity = 79/340 (23.24%), Postives = 137/340 (40.29%), Query Frame = 3
Query: 168 NIRSVEY----VKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFID------YYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRR--KKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLI----YFLS--FEKMQAAAKDIQRRIIV 1133
+ R VEY ++ + + D + + ++G G+ + V + K+ E + +A+K ID K + E+ +L ++ N+I+L F + IF+++ V + D YY D + ++ +L A+ ++HEN ++HRD+KP N LY + DFGL+ K ID Q MK +CG T GY PE+ +R VD W+VG+I+ I L G PFF D ++ ++ F+S ++++ AKD+ ++IV
Sbjct: 7 DARPVEYWVDGSRRDATVEDFYNMGPELGRGATSVVLRCEEKQTE---KPYAVKVLKKTIDKKIVRTEIGVLLRLS-HPNIIRLKEIFETETEIFLILELVTGGELFDRIVERGYYSERDAAHV---IKQILEAVAYLHENGVVHRDLKPENLLYADLSIDAPLKIADFGLS---------------------------KIIDEQVTMK--------------------------TVCG---------------------TPGYCAPEI-LRGNAYGPEVDMWSVGVILYILLCGFEPFFDQRGDQYMYSRILNCDYEFVSPWWDEVSLNAKDLVNKLIV 264
BLAST of cdc7-like protein vs. Ensembl Xenopus
Match: arid1a (AT-rich interaction domain 1A [Source:Xenbase;Acc:XB-GENE-492490]) HSP 1 Score: 189.119 bits (479), Expect = 6.059e-54 Identity = 136/463 (29.37%), Postives = 209/463 (45.14%), Query Frame = 3
Query: 189 VKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHS--EVHGDL----------GSWFDDEDHSDFGNEKIAIKSIDSQNNM----------------KRQDTGTLKSRLSDTSILSESN---QIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFL-SFEKMQAA--------------AKDIQ------RRIIVNPK-------------PLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFD---DSAYDLLSKLLEPKFHTRITCREALQHKFF 1373
V Q +I F I KIGEG+F++V+ + FALK IP P RI EL+ L GG+ NV+ + + FR KDH+ ++MP+++H F D + + E ++Y+ NLL AL+ +H I+HRDVKP+NFLY+R KKF LVDFGLA + DL G + S FG + S + +N K T+ ++ + +S+ +++ Q +C C + C+ C R R GT G+R PEV + QTTA+D W+ GII L+G+Y FF DD++ ++ S E +QA+ +KD++ R ++ P + ++ + W I + + + + N +D + AY LL +LL+ TRIT EAL H F
Sbjct: 20 VPQLRNI---FYIKSKIGEGTFSSVYLAIGRLRSGEDVTFALKHLIPTSHPTRIAAELQCLSVAGGEDNVMGVKYCFRNKDHVVIVMPYLEHECFADILHSLSLEETKEYMFNLLKALRRIHSFGIVHRDVKPSNFLYNRSLKKFALVDFGLAQGTPDTKIDLLKVLQPKKQEGLFGSSAQRSVFGERNFNVHSAVTTDNTTLKAVKPSKMLDVTTRKLATRKTVSAKSTSSSVNKKASSICQTSLACDCYAKDQVCNICLARTRQVAPRAGTPGFRAPEVLTKCPHQTTAIDMWSAGIIFLSLLSGRYHFFNAADDMNALAQIMTIRGSKETIQASKCFGKNLLCSKELPSKDLKTLCEGLRSAVLLPNGDQHDIQKQRAALQMQIMENQDGWFSPESSNITHASSMVASCVSAPDNMDIEQSNLNGWDRVPNEAYHLLDRLLDMNPATRITAEEALIHPLF 479
BLAST of cdc7-like protein vs. Ensembl Xenopus
Match: arid1a (AT-rich interaction domain 1A [Source:Xenbase;Acc:XB-GENE-492490]) HSP 1 Score: 181.8 bits (460), Expect = 5.862e-51 Identity = 137/488 (28.07%), Postives = 211/488 (43.24%), Query Frame = 3
Query: 189 VKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAH---------------------SEVHGDL--GSWF--------------DDEDHSDFGNEKIAIKSIDSQNNM----------------KRQDTGTLKSRLSDTSILSESN---QIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFL-SFEKMQAA--------------AKDIQ------RRIIVNPK-------------PLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFD---DSAYDLLSKLLEPKFHTRITCREALQHKFF 1373
V Q +I F I KIGEG+F++V+ + FALK IP P RI EL+ L GG+ NV+ + + FR KDH+ ++MP+++H F D + + E ++Y+ NLL AL+ +H I+HRDVKP+NFLY+R KKF LVDFGLA S+ H + G+W S FG + S + +N K T+ ++ + +S+ +++ Q +C C + C+ C R R GT G+R PEV + QTTA+D W+ GII L+G+Y FF DD++ ++ S E +QA+ +KD++ R ++ P + ++ + W I + + + + N +D + AY LL +LL+ TRIT EAL H F
Sbjct: 18 VPQLRNI---FYIKSKIGEGTFSSVYLAIGRLRSGEDVTFALKHLIPTSHPTRIAAELQCLSVAGGEDNVMGVKYCFRNKDHVVIVMPYLEHECFADILHSLSLEETKEYMFNLLKALRRIHSFGIVHRDVKPSNFLYNRSLKKFALVDFGLAQGTPDTKIDLLKVLQPKKQGSCSQNHPYIISGNWVHQNIPVLRKEGLFGSSAQRSVFGERNFNVHSAVTTDNTTLKAVKPSKMLDVTTRKLATRKTVSAKSTSSSVNKKASSICQTSLACDCYAKDQVCNICLARTRQVAPRAGTPGFRAPEVLTKCPHQTTAIDMWSAGIIFLSLLSGRYHFFNAADDMNALAQIMTIRGSKETIQASKCFGKNLLCSKELPSKDLKTLCEGLRSAVLLPNGDQHDIQKQRAALQMQIMENQDGWFSPESSNITHASSMVASCVSAPDNMDIEQSNLNGWDRVPNEAYHLLDRLLDMNPATRITAEEALIHPLF 502
BLAST of cdc7-like protein vs. Ensembl Xenopus
Match: arid1a (AT-rich interaction domain 1A [Source:Xenbase;Acc:XB-GENE-492490]) HSP 1 Score: 134.035 bits (336), Expect = 1.816e-33 Identity = 68/154 (44.16%), Postives = 95/154 (61.69%), Query Frame = 3
Query: 189 VKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAH 650
V Q +I F I KIGEG+F++V+ + FALK IP P RI EL+ L GG+ NV+ + + FR KDH+ ++MP+++H F D + + E ++Y+ NLL AL+ +H I+HRDVKP+NFLY+R KKF LVDFGLA
Sbjct: 37 VPQLRNI---FYIKSKIGEGTFSSVYLAIGRLRSGEDVTFALKHLIPTSHPTRIAAELQCLSVAGGEDNVMGVKYCFRNKDHVVIVMPYLEHECFADILHSLSLEETKEYMFNLLKALRRIHSFGIVHRDVKPSNFLYNRSLKKFALVDFGLAQ 187 HSP 2 Score: 74.7146 bits (182), Expect = 9.938e-14 Identity = 68/294 (23.13%), Postives = 113/294 (38.44%), Query Frame = 3
Query: 660 HGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNM----------------KRQDTGTLKSRLSDTSILSESN---QIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFL-SFEKMQAA--------------AKDIQ------RRIIVNPK-------------PLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFD---DSAYDLLSKLLEPKFHTRITCREALQHKFF 1373
HG G + S FG + S + +N K T+ ++ + +S+ +++ Q +C C + C+ C R R GT G+R PEV + QTTA+D W+ GII L+G+Y FF DD++ ++ S E +QA+ +KD++ R ++ P + ++ + W I + + + + N +D + AY LL +LL+ TRIT EAL H F
Sbjct: 256 HGQEGLFGSSAQRSVFGERNFNVHSAVTTDNTTLKVIKPSKMLDVTTRKLATRKTVSAKSTSSSVNKKASSICQTSLACDCYAKDQVCNICLARTRQVAPRAGTPGFRAPEVLTKCPHQTTAIDMWSAGIIFLSLLSGRYHFFNAADDMNALAQIMTIRGSKETIQASKCFGKNLLCSKELPSKDLKTLCEGLRSAVLLPNGDQHDIQKQRAALQMQIMENQDGWFSPESSNITHASSMVASCVSAPDNMDIEQSNLNGWDRVPNEAYHLLDRLLDMNPATRITAEEALIHPLF 549
BLAST of cdc7-like protein vs. Ensembl Xenopus
Match: arid1a (AT-rich interaction domain 1A [Source:Xenbase;Acc:XB-GENE-492490]) HSP 1 Score: 134.035 bits (336), Expect = 2.119e-33 Identity = 68/154 (44.16%), Postives = 95/154 (61.69%), Query Frame = 3
Query: 189 VKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAH 650
V Q +I F I KIGEG+F++V+ + FALK IP P RI EL+ L GG+ NV+ + + FR KDH+ ++MP+++H F D + + E ++Y+ NLL AL+ +H I+HRDVKP+NFLY+R KKF LVDFGLA
Sbjct: 46 VPQLRNI---FYIKSKIGEGTFSSVYLAIGRLRSGEDVTFALKHLIPTSHPTRIAAELQCLSVAGGEDNVMGVKYCFRNKDHVVIVMPYLEHECFADILHSLSLEETKEYMFNLLKALRRIHSFGIVHRDVKPSNFLYNRSLKKFALVDFGLAQ 196 HSP 2 Score: 75.485 bits (184), Expect = 6.215e-14 Identity = 67/285 (23.51%), Postives = 111/285 (38.95%), Query Frame = 3
Query: 660 HGDLGSWFDDEDHSDFGNEKIAIKSIDSQ-------NNMKRQDTGTLKSRLSDTSILSESN---QIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFL-SFEKMQAA--------------AKDIQ------RRIIVNPK-------------PLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFD---DSAYDLLSKLLEPKFHTRITCREALQHKFF 1373
HG G + S FG + S + K T+ ++ + +S+ +++ Q +C C + C+ C R R GT G+R PEV + QTTA+D W+ GII L+G+Y FF DD++ ++ S E +QA+ +KD++ R ++ P + ++ + W I + + + + N +D + AY LL +LL+ TRIT EAL H F
Sbjct: 265 HGQEGLFGSSAQRSVFGERNFNVHSAAVKPSKMLDVTTRKLATRKTVSAKSTSSSVNKKASSICQTSLACDCYAKDQVCNICLARTRQVAPRAGTPGFRAPEVLTKCPHQTTAIDMWSAGIIFLSLLSGRYHFFNAADDMNALAQIMTIRGSKETIQASKCFGKNLLCSKELPSKDLKTLCEGLRSAVLLPNGDQHDIQKQRAALQMQIMENQDGWFSPESSNITHASSMVASCVSAPDNMDIEQSNLNGWDRVPNEAYHLLDRLLDMNPATRITAEEALIHPLF 549
BLAST of cdc7-like protein vs. Ensembl Xenopus
Match: arid1a (AT-rich interaction domain 1A [Source:Xenbase;Acc:XB-GENE-492490]) HSP 1 Score: 133.65 bits (335), Expect = 2.933e-33 Identity = 68/154 (44.16%), Postives = 95/154 (61.69%), Query Frame = 3
Query: 189 VKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAH 650
V Q +I F I KIGEG+F++V+ + FALK IP P RI EL+ L GG+ NV+ + + FR KDH+ ++MP+++H F D + + E ++Y+ NLL AL+ +H I+HRDVKP+NFLY+R KKF LVDFGLA
Sbjct: 41 VPQLRNI---FYIKSKIGEGTFSSVYLAIGRLRSGEDVTFALKHLIPTSHPTRIAAELQCLSVAGGEDNVMGVKYCFRNKDHVVIVMPYLEHECFADILHSLSLEETKEYMFNLLKALRRIHSFGIVHRDVKPSNFLYNRSLKKFALVDFGLAQ 191 HSP 2 Score: 75.0998 bits (183), Expect = 6.839e-14 Identity = 68/294 (23.13%), Postives = 113/294 (38.44%), Query Frame = 3
Query: 660 HGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNM----------------KRQDTGTLKSRLSDTSILSESN---QIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFL-SFEKMQAA--------------AKDIQ------RRIIVNPK-------------PLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFD---DSAYDLLSKLLEPKFHTRITCREALQHKFF 1373
HG G + S FG + S + +N K T+ ++ + +S+ +++ Q +C C + C+ C R R GT G+R PEV + QTTA+D W+ GII L+G+Y FF DD++ ++ S E +QA+ +KD++ R ++ P + ++ + W I + + + + N +D + AY LL +LL+ TRIT EAL H F
Sbjct: 260 HGQEGLFGSSAQRSVFGERNFNVHSAVTTDNTTLKVIKPSKMLDVTTRKLATRKTVSAKSTSSSVNKKASSICQTSLACDCYAKDQVCNICLARTRQVAPRAGTPGFRAPEVLTKCPHQTTAIDMWSAGIIFLSLLSGRYHFFNAADDMNALAQIMTIRGSKETIQASKCFGKNLLCSKELPSKDLKTLCEGLRSAVLLPNGDQHDIQKQRAALQMQIMENQDGWFSPESSNITHASSMVASCVSAPDNMDIEQSNLNGWDRVPNEAYHLLDRLLDMNPATRITAEEALIHPLF 553
BLAST of cdc7-like protein vs. Ensembl Mouse
Match: Cdc7 (cell division cycle 7 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1309511]) HSP 1 Score: 200.29 bits (508), Expect = 1.011e-57 Identity = 130/422 (30.81%), Postives = 200/422 (47.39%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHS------EVHGDLGSWFDDED------HSDFGNEKI----AIKSIDSQ----NNMKRQDTGTLKSRLSDTSILSESNQIE--------------------------------ASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSA 1292
E V Q ++ F+I DKIGEG+F++V+ ++ E +E ALK IP P RI EL+ L GG+ NV+ L + FR DH+ + MP+++H F+D + E+R+Y+ NL VALK +H+ I+HRDVKP+NFLY+RR KK+ LVDFGLA E+ + S ED H G++ + A K++D Q ++KR T + D ++ +S ++ +C C C C +R R GT G+R PEV + +QTTA+D W+ G+I L+G+YPF+K DDL ++ + AAK + ++ + K +P Q +R CE++ L +A +D +A
Sbjct: 43 EAVPQLVNV---FKIKDKIGEGTFSSVYLATAQLQEGHEEKIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTRDTKIELLKFVQSEAQQEDCSRNKYHGVVGHKGLLSRPAPKTVDQQCTPKTSVKRSYTQVHIKQGKDGKLIKQSKTVDIISRKLATKKTAISTKAMNSVMRETARSCPAVLTCDCYGSDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSVLCS-KEVP------------AQDLRALCERLRGLDSTTPRSASGPPGNASYDPAA 448
BLAST of cdc7-like protein vs. Ensembl Mouse
Match: Cdc7 (cell division cycle 7 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1309511]) HSP 1 Score: 183.341 bits (464), Expect = 1.640e-51 Identity = 127/422 (30.09%), Postives = 195/422 (46.21%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHS------EVHGDLGSWFDDED------HSDFGNEKI----AIKSIDSQ----NNMKRQDTGTLKSRLSDTSILSESNQIE--------------------------------ASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSA 1292
E V Q ++ F+I DKIGEG+F++V+ ++ E +E ALK IP P RI EL+ L GG+ NV+ L + FR DH+ + MP+++H F+D + E+R+Y+ NL VALK +H+ I+HRDVKP+NFLY+RR KK+ LVDFGLA E+ + S ED H G++ + A K++D Q ++KR T + D ++ +S ++ +C C C C +R R GT G+R PEV + +QTT G+I L+G+YPF+K DDL ++ + AAK + ++ + K +P Q +R CE++ L +A +D +A
Sbjct: 43 EAVPQLVNV---FKIKDKIGEGTFSSVYLATAQLQEGHEEKIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTRDTKIELLKFVQSEAQQEDCSRNKYHGVVGHKGLLSRPAPKTVDQQCTPKTSVKRSYTQVHIKQGKDGKLIKQSKTVDIISRKLATKKTAISTKAMNSVMRETARSCPAVLTCDCYGSDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTT-------GVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSVLCS-KEVP------------AQDLRALCERLRGLDSTTPRSASGPPGNASYDPAA 441
BLAST of cdc7-like protein vs. Ensembl Mouse
Match: Cdc7 (cell division cycle 7 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1309511]) HSP 1 Score: 145.976 bits (367), Expect = 1.273e-39 Identity = 72/157 (45.86%), Postives = 102/157 (64.97%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHS 653
E V Q ++ F+I DKIGEG+F++V+ ++ E +E ALK IP P RI EL+ L GG+ NV+ L + FR DH+ + MP+++H F+D + E+R+Y+ NL VALK +H+ I+HRDVKP+NFLY+RR KK+ LVDFGLA
Sbjct: 43 EAVPQLVNV---FKIKDKIGEGTFSSVYLATAQLQEGHEEKIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQG 196
BLAST of cdc7-like protein vs. Ensembl Mouse
Match: Cdc7 (cell division cycle 7 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1309511]) HSP 1 Score: 149.443 bits (376), Expect = 6.414e-39 Identity = 72/156 (46.15%), Postives = 102/156 (65.38%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAH 650
E V Q ++ F+I DKIGEG+F++V+ ++ E +E ALK IP P RI EL+ L GG+ NV+ L + FR DH+ + MP+++H F+D + E+R+Y+ NL VALK +H+ I+HRDVKP+NFLY+RR KK+ LVDFGLA
Sbjct: 43 EAVPQLVNV---FKIKDKIGEGTFSSVYLATAQLQEGHEEKIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQ 195 HSP 2 Score: 76.2554 bits (186), Expect = 2.558e-14 Identity = 43/153 (28.10%), Postives = 68/153 (44.44%), Query Frame = 3
Query: 834 SCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSA 1292
+C C C C +R R GT G+R PEV + +QTTA+D W+ G+I L+G+YPF+K DDL ++ + AAK + ++ + K +P Q +R CE++ L +A +D +A
Sbjct: 341 TCDCYGSDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSVLCS-KEVP------------AQDLRALCERLRGLDSTTPRSASGPPGNASYDPAA 480
BLAST of cdc7-like protein vs. Ensembl Mouse
Match: Cdc7 (cell division cycle 7 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1309511]) HSP 1 Score: 149.443 bits (376), Expect = 6.414e-39 Identity = 72/156 (46.15%), Postives = 102/156 (65.38%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAH 650
E V Q ++ F+I DKIGEG+F++V+ ++ E +E ALK IP P RI EL+ L GG+ NV+ L + FR DH+ + MP+++H F+D + E+R+Y+ NL VALK +H+ I+HRDVKP+NFLY+RR KK+ LVDFGLA
Sbjct: 43 EAVPQLVNV---FKIKDKIGEGTFSSVYLATAQLQEGHEEKIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQ 195 HSP 2 Score: 76.2554 bits (186), Expect = 2.558e-14 Identity = 43/153 (28.10%), Postives = 68/153 (44.44%), Query Frame = 3
Query: 834 SCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSA 1292
+C C C C +R R GT G+R PEV + +QTTA+D W+ G+I L+G+YPF+K DDL ++ + AAK + ++ + K +P Q +R CE++ L +A +D +A
Sbjct: 341 TCDCYGSDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSVLCS-KEVP------------AQDLRALCERLRGLDSTTPRSASGPPGNASYDPAA 480
BLAST of cdc7-like protein vs. UniProt/SwissProt
Match: sp|Q8SR83|CDC72_ENCCU (Probable cell division control protein 7 homolog 2 OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813 GN=CDC7-2 PE=3 SV=1) HSP 1 Score: 170.244 bits (430), Expect = 2.533e-47 Identity = 119/396 (30.05%), Postives = 184/396 (46.46%), Query Frame = 3
Query: 189 VKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSAYDLLSKLLEPKFHTRITCREALQHKFFN 1376
++ S + + I+KIGEGSF+ V+K + ALK P R+ +E+ LK +GG+KN + L FR +D + + P+ + I F ++ ++ +I+ YL NLL+A++HVH N I+HRD+KP NFLY++ + L+DFGLA E + + H++ G + G L L S++S++ + + RP + R GT G+R PEV R QT A+D W+VG+I LT +YPFF DD+D + +M+ AAK R N +P + R F E I + + AE YDLL ++L+ +RIT +AL H FF+
Sbjct: 11 LRHISFVMPKYTPIEKIGEGSFSVVYKALDAES---GRYVALKAITRTSSPARVLDEMMFLKTLGGRKNCMGLLGCFRNEDQVVAVFPYFEPIDFREFISNANLADIKRYLHNLLIAIEHVHSNGIMHRDLKPGNFLYNKESGRGMLIDFGLAQYEE-------YSEGQHAEGGA----------------KPAGPL---LFFNSVVSKT-----------KPPGYYERDGRPPMKAPRAGTRGFRAPEVLFRCQRQTGAIDMWSVGVIFLTILTTQYPFFYSSDDIDSIVEIATIFGHAEMRKAAKFYGRVWRSNIDSIP---------EERIPF-----ETIVESLNP----------WAEVGSDGYDLLYRMLDLCSSSRITASDALSHPFFD 342
BLAST of cdc7-like protein vs. UniProt/SwissProt
Match: sp|Q8SR85|CDC71_ENCCU (Probable cell division control protein 7 homolog 1 OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813 GN=CDC7-1 PE=3 SV=1) HSP 1 Score: 169.859 bits (429), Expect = 2.587e-47 Identity = 119/396 (30.05%), Postives = 184/396 (46.46%), Query Frame = 3
Query: 189 VKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSAYDLLSKLLEPKFHTRITCREALQHKFFN 1376
++ S + + I+KIGEGSF+ V+K + ALK P R+ +E+ LK +GG+KN + L FR +D + + P+ + I F ++ ++ +I+ YL NLL+A++HVH N I+HRD+KP NFLY++ + L+DFGLA E + + H++ G + G L L S++S++ + + RP + R GT G+R PEV R QT A+D W+VG+I LT +YPFF DD+D + +M+ AAK R N +P + R F E I + + AE YDLL ++L+ +RIT +AL H FF+
Sbjct: 11 LRHISFVMPKYTPIEKIGEGSFSVVYKALDAES---GRYVALKAITRTSSPARVLDEMMFLKTLGGRKNCMGLLGCFRNEDQVVAVFPYFEPIDFREFISNANLADIKRYLHNLLIAIEHVHSNGIMHRDLKPGNFLYNKESGRGMLIDFGLAQYEE-------YSEGQHAEGGA----------------KPAGPL---LFFNSVVSKT-----------KPPGYYERDGRPPMKAPRAGTRGFRAPEVLFRCQRQTGAIDMWSVGVIFLTILTTQYPFFYSSDDIDSIVEIATIFGHAEMRKAAKFYGRVWRSNIDSIP---------EERIPF-----ETIVESLNP----------WAEIGSDGYDLLYRMLDLCSSSRITASDALSHPFFD 342
BLAST of cdc7-like protein vs. UniProt/SwissProt
Match: sp|Q9UQY9|SPO4_SCHPO (Cell cycle protein kinase spo4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=spo4 PE=1 SV=1) HSP 1 Score: 163.696 bits (413), Expect = 3.520e-44 Identity = 116/421 (27.55%), Postives = 193/421 (45.84%), Query Frame = 3
Query: 189 VKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIF-----------------------ALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDS-QNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDS-AYDLLSKLLEPKFHTRITCREALQHKFFN 1376
V+ F I +++ ++ +G GSF++VFK + + + ALK + P RI+ EL +L ++ G V+ + A R +D + +++PF+ H +F D+Y+ + EI YLR+LL L H+ IIHRD+KP NF ++ ++ ++DFGLA W +D E + + + K D + ++D E + RP + R GT G+R PEV R QT+++D W+VG+I+ FLT +YPFF+ +DD+D L + M A + +I + P L+ ++W+ + I + K+ D+N I +++ + A DLL KLLE R+ + ALQH+FFN
Sbjct: 30 VQAFPTIEEDYHVVKLVGAGSFSSVFKAVDRHFDSYDNSYWISSQIEDQMPHDKTKRPKNHFVALKRIYATVLPSRIQTELEMLHELRGSDCVLNMITAVRHQDQVLIVLPFIQHAEFRDFYMKYSLPEIGAYLRDLLKGLAHIDAKGIIHRDIKPGNFAWNPYTQRGVILDFGLAQ---------W----QEADAPTENCCVDKLRKLKQEGKYYDYFPFEKTIADPP--------EGYLLHD----------PRPTKRADRAGTRGFRAPEVLFRCQNQTSSIDVWSVGVILLCFLTHRYPFFRCEDDIDAIVELAHIFGRNGMSNCAL-LHGQIWSDNIPT-LLDQKHNWL-----------DLIASITKN--DENLILETSSDYQVALAIDLLDKLLELHPSKRVKAKTALQHEFFN 404
BLAST of cdc7-like protein vs. UniProt/SwissProt
Match: sp|Q9Z0H0|CDC7_MOUSE (Cell division cycle 7-related protein kinase OS=Mus musculus OX=10090 GN=Cdc7 PE=1 SV=2) HSP 1 Score: 149.443 bits (376), Expect = 4.486e-38 Identity = 72/156 (46.15%), Postives = 102/156 (65.38%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAH 650
E V Q ++ F+I DKIGEG+F++V+ ++ E +E ALK IP P RI EL+ L GG+ NV+ L + FR DH+ + MP+++H F+D + E+R+Y+ NL VALK +H+ I+HRDVKP+NFLY+RR KK+ LVDFGLA
Sbjct: 43 EAVPQLVNV---FKIKDKIGEGTFSSVYLATAQLQEGHEEKIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQ 195 HSP 2 Score: 76.2554 bits (186), Expect = 1.789e-13 Identity = 43/153 (28.10%), Postives = 68/153 (44.44%), Query Frame = 3
Query: 834 SCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSA 1292
+C C C C +R R GT G+R PEV + +QTTA+D W+ G+I L+G+YPF+K DDL ++ + AAK + ++ + K +P Q +R CE++ L +A +D +A
Sbjct: 341 TCDCYGSDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSVLCS-KEVP------------AQDLRALCERLRGLDSTTPRSASGPPGNASYDPAA 480
BLAST of cdc7-like protein vs. UniProt/SwissProt
Match: sp|P06243|CDC7_YEAST (Cell division control protein 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CDC7 PE=1 SV=2) HSP 1 Score: 144.05 bits (362), Expect = 1.676e-36 Identity = 96/319 (30.09%), Postives = 159/319 (49.84%), Query Frame = 3
Query: 207 INDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEI-----------FALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDE-DHSDFGNEK-IAIKSIDSQNN-----MKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHG-CRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAA 1106
I + +++IDKIGEG+F++V+K + ++ K+ ALK P+RI NEL +L + G V L A RV+D + ++P+ H +F +Y + I I+ Y+ LL ALK VH IIHRD+KP NFL++ + LVDFGLA +++ D S + D+ ++ N S+ + M+ Q + ++ + + + + G LT + TR + R GT G+R PEV M+ Q+T +D W+VG+I+ L ++P F+ DD D L +++++ A
Sbjct: 29 IENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSSPQRIYNELNLLYIMTGSSRVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDLPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLVDFGLAEAQM--DYKSMISSQNDYDNYANTNHDGGYSMRNHEQFCPCIMRNQYSPNSHNQTPPMVTIQNGKVVHLNNVNGVDLTKGYPKNETRRIKRANRAGTRGFRAPEVLMKCGAQSTKIDIWSVGVILLSLLGRRFPMFQSLDDADSLLELCTIFGWKELRKCA 345
BLAST of cdc7-like protein vs. TrEMBL
Match: D2DJV6 (Cdc7-like protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 460.685 bits (1184), Expect = 4.552e-160 Identity = 217/217 (100.00%), Postives = 217/217 (100.00%), Query Frame = 3
Query: 630 VDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEF 1280
VDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEF
Sbjct: 1 VDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEF 217
BLAST of cdc7-like protein vs. TrEMBL
Match: G4VG92 (Serine/threonine kinase OS=Schistosoma mansoni OX=6183 GN=Smp_177120 PE=4 SV=1) HSP 1 Score: 374.785 bits (961), Expect = 3.027e-122 Identity = 194/432 (44.91%), Postives = 269/432 (62.27%), Query Frame = 3
Query: 171 IRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSE----------VHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPH-PQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFND--WIKSRC---------QFIRKNCEKITKLIKDNSDKNCIYGNHAE---------FDDSAYDLLSKLLEPKFHTRITCREALQHKFF 1373
+RS++Y+ +F I D F + ++ G+G+FA+V VRSK+ + +ALK IP +D +RIENE+RIL+++GGK NVI++H A R++DH+F+LMPF+D+I F +YYL D EIR Y+R LL AL HVH+ K+IHRDVKP NFL D++ K+F LVDFGLAHSE V S+ D D + A K +N ++KS + ++ L++S + C+CG+RLT C GCR P P VRRGGT+G+RPPEV MRH EQTTAVD WAVGII FL+G+YPF KV+DDLDV H+ + + +E+MQ A+ I RR++++P+P P+ + + W+K R +RK K T L DNS + N F SAYDLL++LLEP RIT ++AL H +F
Sbjct: 6 VRSLQYIFEFPQITDLFNVSERQGQGTFASVLAVRSKQDPDESKYYALKMIIPTVDVRRIENEIRILRRLGGKHNVIQMHTAMRIRDHVFILMPFIDYIPFTEYYLTADEKEIRRYMRALLSALAHVHKYKVIHRDVKPTNFLMDQKTKQFFLVDFGLAHSEDISENNQRVNVTNRENSYTHKRDCVDSTSTLFAYKCNSKIDNKSSFKGASVKSSQTISNNLTQSLG-QGGCVCGSRLTVCRGCRHLPRAPTVRRGGTLGFRPPEVMMRHIEQTTAVDIWAVGIIFISFLSGRYPFIKVEDDLDVLHAFTHLIGYERMQMGARSIGRRLLLDPRPPPMEASDSPVMWLKIRLYEKKFAGLPPLLRKTSTKSTNLTNDNSIQTTELSNGKPMIALSSTHIFPTSAYDLLARLLEPCPQKRITAQDALHHPYF 436
BLAST of cdc7-like protein vs. TrEMBL
Match: A0A3Q0KTJ7 (Serine/threonine kinase OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 372.474 bits (955), Expect = 8.354e-121 Identity = 202/474 (42.62%), Postives = 279/474 (58.86%), Query Frame = 3
Query: 171 IRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGS-W---FDDEDHSDF---------------------GNEKIAIKSIDSQNNMKR---QDTGTL-----------KSRLSDTSILSE---SNQI-----EASCICGNRLTTCHGCRTRPH-PQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFND--WIKSRCQ--------------FIRKNCEKITKLIKDNSDKNCIYGNHAE---------FDDSAYDLLSKLLEPKFHTRITCREALQHKFF 1373
+RS++Y+ +F I D F + ++ G+G+FA+V VRSK+ + +ALK IP +D +RIENE+RIL+++GGK NVI++H A R++DH+F+LMPF+D+I F +YYL D EIR Y+R LL AL HVH+ K+IHRDVKP NFL D++ K+F LVDFGLAHSE GD+ W F+ + SD N+++ + + ++ KR T TL KS S+ S SN + + C+CG+RLT C GCR P P VRRGGT+G+RPPEV MRH EQTTAVD WAVGII FL+G+YPF KV+DDLDV H+ + + +E+MQ A+ I RR++++P+P P+ + + W+K RC +RK K T L DNS + N F SAYDLL++LLEP RIT ++AL H +F
Sbjct: 6 VRSLQYIFEFPQITDLFNVSERQGQGTFASVLAVRSKQDPDESKYYALKMIIPTVDVRRIENEIRILRRLGGKHNVIQMHTAMRIRDHVFILMPFIDYIPFTEYYLTADEKEIRRYMRALLSALAHVHKYKVIHRDVKPTNFLMDQKTKQFFLVDFGLAHSEEFGDIDERWERKFEIKSDSDTKKNELMKRISSFPRTNPSISENNQRVNVTNRENSYTHKRDCVDSTSTLFAYKCNSKIDNKSSFKGASVKSSQTISNNLTQSLGQGGCVCGSRLTVCRGCRHLPRAPTVRRGGTLGFRPPEVMMRHIEQTTAVDIWAVGIIFISFLSGRYPFIKVEDDLDVLHAFTHLIGYERMQMGARSIGRRLLLDPRPPPMEASDSPVMWLKIRCSAIRLYEKKFAGLPPLLRKTSTKSTNLTNDNSIQTTELSNGKPMIALSSTHIFPTSAYDLLARLLEPCPQKRITAQDALHHPYF 479
BLAST of cdc7-like protein vs. TrEMBL
Match: A0A2H1CIK5 (Kinase domain protein OS=Fasciola hepatica OX=6192 GN=D915_06234 PE=4 SV=1) HSP 1 Score: 372.089 bits (954), Expect = 1.533e-120 Identity = 202/476 (42.44%), Postives = 276/476 (57.98%), Query Frame = 3
Query: 171 IRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGS-WFDDED-------HSDFGNEKIAIKSIDSQNN------------------MKRQDTGTLKSRLSDTSILSES-----------------------NQIEASCICGNRLTTCHGCRTRPH-PQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFND--WIKSRCQFIRKNCEKITKLI------KDNSDKN----------------CIYGNHAEFDDSAYDLLSKLLEPKFHTRITCREALQHKFFN 1376
+R+V Y++ F +IND F I+DK G+G+FA+VF V+ K K ++ALK IP +D +RIENELRIL+++GGK N++K+H A RV+DH+F+LMPF++ F +YYL D NEI Y+R+LL AL +VH +IIHRDVKP NFL D K+F LVDFGLAHSE +GD+ W D D H+ K + +++N + ++T T S + +S+ + I +C+CG R+T C GCR P RRGGT+G+RPPEV MRH EQTTAVD WAVG+I+ FL+G+YPF KVDDDLDV H+ + + +E+MQA AK + RR++V+PKP P+ A W+K RC IRK +K L K SDKN + +H F SAYDL++KLLEP + R++ EAL+H F N
Sbjct: 6 VRNVSYLRTFPEINDAFTIVDKRGQGTFASVFAVKDKNKPDSKRVYALKMLIPTVDVRRIENELRILRRLGGKCNIVKMHTALRVRDHVFILMPFINFTPFSEYYLSADENEIVRYIRSLLFALSYVHRYRIIHRDVKPTNFLMDSTTKRFYLVDFGLAHSENYGDVDERWELDCDVYEENLKHAHSRKSKRPLSPSSNKDNHQNKTPRLADDLRPSLAVLNSENTPTFPSPDASSSMRIPAATVPHKVVGRATVNHTPSSTVAHTAIPGACVCGFRMTICRGCRQLPRITAARRGGTLGFRPPEVMMRHVEQTTAVDVWAVGVILLSFLSGRYPFIKVDDDLDVLHAFTHLIGYERMQACAKALGRRLLVDPKPPPMEAAETPATWLKLRCVAIRKQEKKFAGLPPLLSNEKKVSDKNGVSTGLTTIESKKNVIALPASHV-FPLSAYDLMAKLLEPSPNKRVSAYEALRHPFLN 480
BLAST of cdc7-like protein vs. TrEMBL
Match: A0A4E0RF94 (Cell division cycle 7 protein kinase OS=Fasciola hepatica OX=6192 GN=D915_004111 PE=4 SV=1) HSP 1 Score: 371.703 bits (953), Expect = 5.278e-120 Identity = 202/476 (42.44%), Postives = 276/476 (57.98%), Query Frame = 3
Query: 171 IRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGS-WFDDED-------HSDFGNEKIAIKSIDSQNN------------------MKRQDTGTLKSRLSDTSILSES-----------------------NQIEASCICGNRLTTCHGCRTRPH-PQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFND--WIKSRCQFIRKNCEKITKLI------KDNSDKN----------------CIYGNHAEFDDSAYDLLSKLLEPKFHTRITCREALQHKFFN 1376
+R+V Y++ F +IND F I+DK G+G+FA+VF V+ K K ++ALK IP +D +RIENELRIL+++GGK N++K+H A RV+DH+F+LMPF++ F +YYL D NEI Y+R+LL AL +VH +IIHRDVKP NFL D K+F LVDFGLAHSE +GD+ W D D H+ K + +++N + ++T T S + +S+ + I +C+CG R+T C GCR P RRGGT+G+RPPEV MRH EQTTAVD WAVG+I+ FL+G+YPF KVDDDLDV H+ + + +E+MQA AK + RR++V+PKP P+ A W+K RC IRK +K L K SDKN + +H F SAYDL++KLLEP + R++ EAL+H F N
Sbjct: 33 VRNVSYLRTFPEINDAFTIVDKRGQGTFASVFAVKDKNKPDSKRVYALKMLIPTVDVRRIENELRILRRLGGKCNIVKMHTALRVRDHVFILMPFINFTPFSEYYLSADENEIVRYIRSLLFALSYVHRYRIIHRDVKPTNFLMDSTTKRFYLVDFGLAHSENYGDVDERWELDCDVYEENLKHAHSRKSKRPLSPSSNKDNHQNKTPRLADDLRPSLAVLNSENTPTFPSPDASSSMRIPAATVPHKVVGRATVNHTPSSTVAHTAIPGACVCGFRMTICRGCRQLPRITAARRGGTLGFRPPEVMMRHVEQTTAVDVWAVGVILLSFLSGRYPFIKVDDDLDVLHAFTHLIGYERMQACAKALGRRLLVDPKPPPMEAAETPATWLKLRCVAIRKQEKKFAGLPPLLSNEKKVSDKNGVSTGLTTIESKKNVIALPASHV-FPLSAYDLMAKLLEPSPNKRVSAYEALRHPFLN 507
BLAST of cdc7-like protein vs. Ensembl Cavefish
Match: cdc7 (cell division cycle 7 homolog (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-041114-113]) HSP 1 Score: 204.142 bits (518), Expect = 2.480e-60 Identity = 115/326 (35.28%), Postives = 175/326 (53.68%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLT--TCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPL 1154
E V Q S + F I DKIGEG+F++V+ ++ + +E FALK IP P RI EL+ L GGK+NV+ + + FR + H+ ++MP+V+H F++ + E++ Y+ +LL ALKH+HE IIHRD+KP NFLY+RR K++ LVDFGLA + E +A + S KR+ L +R S T + + + C +T C+ C +R R GT G+R PEV + Q TA+D W+ G+I+ L+G+YPFFK DDL ++ ++ AA+ + I+ + + PL
Sbjct: 24 EVVPQLSRV---FRITDKIGEGTFSSVYLGEAQMTDGRREKFALKHLIPTSHPVRIAAELQCLTVAGGKENVMGVTYCFRKEHHVVIVMPYVEHQPFVEIVGTLSFEEVQHYIYHLLKALKHIHEFGIIHRDIKPTNFLYNRREKQYALVDFGLAQGTPDTQI-ELLKAPLLKPTKTEDVAARRFVS---TKRRP---LPARSSTTGQKPKPTSLNPALTCSCYMTDHICNICLSRKQQVAPRAGTPGFRAPEVLTKCPNQGTAIDIWSAGVILLSLLSGRYPFFKASDDLLALTQIMTIRGSKETAQAARKFGKAIVCSRELPPL 339
BLAST of cdc7-like protein vs. Ensembl Cavefish
Match: cdc7 (cell division cycle 7 homolog (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-041114-113]) HSP 1 Score: 149.058 bits (375), Expect = 5.999e-39 Identity = 71/157 (45.22%), Postives = 103/157 (65.61%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHS 653
E V Q S + F I DKIGEG+F++V+ ++ + +E FALK IP P RI EL+ L GGK+NV+ + + FR + H+ ++MP+V+H F++ + E++ Y+ +LL ALKH+HE IIHRD+KP NFLY+RR K++ LVDFGLA
Sbjct: 71 EVVPQLSRV---FRITDKIGEGTFSSVYLGEAQMTDGRREKFALKHLIPTSHPVRIAAELQCLTVAGGKENVMGVTYCFRKEHHVVIVMPYVEHQPFVEIVGTLSFEEVQHYIYHLLKALKHIHEFGIIHRDIKPTNFLYNRREKQYALVDFGLAQG 224 HSP 2 Score: 74.3294 bits (181), Expect = 8.707e-14 Identity = 39/128 (30.47%), Postives = 63/128 (49.22%), Query Frame = 3
Query: 777 LKSRLSDTSILSESNQIEASCICGNRLT--TCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPL 1154
L +R S T + + + C +T C+ C +R R GT G+R PEV + Q TA+D W+ G+I+ L+G+YPFFK DDL ++ ++ AA+ + I+ + + PL
Sbjct: 346 LPARSSTTGQKPKPTSLNPALTCSCYMTDHICNICLSRKQQVAPRAGTPGFRAPEVLTKCPNQGTAIDIWSAGVILLSLLSGRYPFFKASDDLLALTQIMTIRGSKETAQAARKFGKAIVCSRELPPL 473
BLAST of cdc7-like protein vs. Ensembl Cavefish
Match: camk1ga (calcium/calmodulin-dependent protein kinase IGa [Source:ZFIN;Acc:ZDB-GENE-030131-7594]) HSP 1 Score: 78.5666 bits (192), Expect = 2.446e-15 Identity = 52/166 (31.33%), Postives = 87/166 (52.41%), Query Frame = 3
Query: 186 YVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALK-FTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRD---YLRNLLVALKHVHENKIIHRDVKPNNFLY--DRRRKKFTLVDFGLAHSEVHG 665
+ K ++I D FE + +G GSF+ VF VR +K +ALK +D +ENE+ +LK+I NV+ L + + H +++M V + D L + +D +R +L A+ ++H+N ++HRD+KP N L+ + K + DFGL+ HG
Sbjct: 10 WKKVTNNIKDVFEFREILGSGSFSEVFLVRERKT---GNFYALKCVKKKQLDHSNLENEITVLKRIK-HNNVVSLEDFYETRTHYYLVMELVSGGELFDRILDRGVYTEKDASLVIRQVLEAVTYLHQNSVVHRDLKPENLLFYNQDEKAKIMISDFGLSKMVDHG 171
BLAST of cdc7-like protein vs. Ensembl Cavefish
Match: camk1gb (calcium/calmodulin-dependent protein kinase type 1D-like [Source:NCBI gene;Acc:103033882]) HSP 1 Score: 76.2554 bits (186), Expect = 1.432e-14 Identity = 49/170 (28.82%), Postives = 89/170 (52.35%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDY---LRNLLVALKHVHENKIIHRDVKPNNFLYDRR--RKKFTLVDFGLAHSEVHGDLGS 677
++ K +I + F+ I+ +G G+ + VFKV+ K + FA+K I +ENE+ +LK+I N++ L + + H +++M V + D L + +D +R +L + ++H+N I+HRD+KP N LY + K + DFGL+ E +G + +
Sbjct: 27 DWKKTVENIREIFDFIEVLGSGASSEVFKVKEKST---GKFFAMKCVIKKNRNTTLENEIAVLKRIK-HNNIVALEDFYETQSHYYLVMQLVSGGELFDRLLDRGMFSEKDASMVIRQVLEGVHYLHQNNIVHRDLKPENLLYYSQDDNSKIMISDFGLSKIEDNGIMST 192
BLAST of cdc7-like protein vs. Ensembl Cavefish
Match: camk1gb (calcium/calmodulin-dependent protein kinase type 1D-like [Source:NCBI gene;Acc:103033882]) HSP 1 Score: 75.485 bits (184), Expect = 2.450e-14 Identity = 48/163 (29.45%), Postives = 84/163 (51.53%), Query Frame = 3
Query: 183 EYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDY---LRNLLVALKHVHENKIIHRDVKPNNFLY--DRRRKKFTLVDFGLAHSE 656
++ K +I + F+ I+ +G G+ + VFKV+ K + FA+K I +ENE+ +LK+I N++ L + + H +++M V + D L + +D +R +L + ++H+N I+HRD+KP N LY K + DFGL+ E
Sbjct: 27 DWKKTVENIREIFDFIEVLGSGASSEVFKVKEKST---GKFFAMKCVIKKNRNTTLENEIAVLKRIK-HNNIVALEDFYETQSHYYLVMQLVSGGELFDRLLDRGMFSEKDASMVIRQVLEGVHYLHQNNIVHRDLKPENLLYYSQDENSKIMISDFGLSKME 185
BLAST of cdc7-like protein vs. Ensembl Sea Lamprey
Match: cdc7 (cell division cycle 7 homolog (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-041114-113]) HSP 1 Score: 140.584 bits (353), Expect = 1.042e-36 Identity = 68/150 (45.33%), Postives = 104/150 (69.33%), Query Frame = 3
Query: 216 NFEIIDKIGEGSFAAVF----KVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHS 653
NF II KIGEG+F++V+ KVR E +E+ A+K+ IP P RI E++ L + GG NV+++ R KDH+ ++MP+++H F + +M++ E+R+Y+RNLLV+L +H+ IIHRDVKP+NFLY R+++++ LVDFGLA
Sbjct: 22 NFNIIRKIGEGTFSSVYMAKGKVRRSGGE--EEMLAVKYLIPTSHPLRIAAEVQCLMEAGGVDNVMEVLQCLRNKDHVVIIMPYLEHEVFSEVVSVMNVMEVREYMRNLLVSLLRIHKLGIIHRDVKPSNFLYCRKQQRYALVDFGLAQG 169 HSP 2 Score: 75.0998 bits (183), Expect = 9.760e-15 Identity = 36/99 (36.36%), Postives = 49/99 (49.49%), Query Frame = 3
Query: 774 TLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLI 1070
T K ++ + + E +C C C C R R GT G+R PEV ++ QTTA+D W+ GII L+G+YPFFK DDL +I
Sbjct: 304 TAKKAVAPPNAMPRCALQEKTCSCFGYDQVCKLCLARSPQPSPRAGTPGFRAPEVLLKWPYQTTAIDIWSTGIIFLCLLSGRYPFFKTSDDLTALAQII 402
BLAST of cdc7-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008748.1 (pep scaffold:Pmarinus_7.0:GL476577:591:63029:-1 gene:ENSPMAG00000007907.1 transcript:ENSPMAT00000008748.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 65.0846 bits (157), Expect = 9.845e-12 Identity = 48/170 (28.24%), Postives = 87/170 (51.18%), Query Frame = 3
Query: 210 NDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKF----TIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFV------DHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRK--KFTLVDFGLAHSEVHGDLGSWF 683
D +++ +++G+G+F+ V R K+ +E FA K + D +++E E RI + + N+++LH + + +++ V + I +YY D + ++ +L ++ H H++ I+HRD+KP N L + K L DFGLA EV GD +WF
Sbjct: 11 TDEYQLYEELGKGAFSVVR--RCVKVSTGQE-FAAKIINTKKLSARDHQKLEREARICRLLK-HSNIVRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHC---IQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLA-IEVQGDQQAWF 172
BLAST of cdc7-like protein vs. Ensembl Sea Lamprey
Match: mast2 (microtubule associated serine/threonine kinase 2 [Source:ZFIN;Acc:ZDB-GENE-050309-150]) HSP 1 Score: 64.3142 bits (155), Expect = 3.884e-11 Identity = 81/352 (23.01%), Postives = 141/352 (40.06%), Query Frame = 3
Query: 174 RSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALK--FTIPIIDPKRIENEL--RILKKIGGKKNVIKLHFAFRVKDHIFMLMPFV---DHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIY--FLSFEKMQAAAKDIQRRI--IVNPKPLPLIGAFNDWIKSRCQF 1196
R+ E + + ++FE I I G++ AV+ VR K+ ++ FA+K +I +I+ R + V+ + +F K H+ M+M +V D + + ++ + Y ++AL+++H I+HRD+KP+N L + H ++ +DFG KI + S L + L + I ++ + +C GT Y PEV +R VD WA+G+I+ FL G PFF D ++F +I + E A D+Q I ++ PL +G + + QF
Sbjct: 199 RAAESLPKKKPCEEDFETIKLISNGAYGAVYLVRHKET---RQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLIT-----------SMGHVKL-------------TDFGLSKIGLMS--------------LTTNLYEEHIEKDTREFLDKQVC---------------------GTPEYIAPEVILRQG-YGKPVDWWAMGVILYEFLVGCVPFFG-DTPEELFGQVISDEIVWPEGEDALPSDVQDLITGLLERNPLERLGTGGAFEVKQHQF 486
BLAST of cdc7-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008013.1 (pep scaffold:Pmarinus_7.0:GL478839:10839:40406:1 gene:ENSPMAG00000007231.1 transcript:ENSPMAT00000008013.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 63.1586 bits (152), Expect = 5.104e-11 Identity = 40/153 (26.14%), Postives = 81/153 (52.94%), Query Frame = 3
Query: 213 DNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYL-----LMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSE 656
+ + +DK+GEG++A V+K RSK + L + ++ P E+ +LK + N++ LH + ++ +++ K + Y+ +M ++ ++ +L LL L + H+ +++HRD+KP N L + + + L DFGLA ++
Sbjct: 196 ETYTKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLK-HANIVTLHDIVHTDKSLTLVFEYLE--KDLKQYMDDCGNIMSMHNVKIFLLQLLRGLAYCHKRRVLHRDLKPQNLLIN-DKGELKLADFGLARAK 344
BLAST of cdc7-like protein vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741]) HSP 1 Score: 61.2326 bits (147), Expect = 9.257e-11 Identity = 45/155 (29.03%), Postives = 79/155 (50.97%), Query Frame = 3
Query: 213 DNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKF----TIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDH--IKFIDYYLL--MDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHS 653
DNF+ ++KIGEG++ V+K R+K + E ALK T P E+ +L+++ N+++L + ++++ +D KF+D + + ++ YL LL + H ++I+HRD+KP N L + L DFGLA +
Sbjct: 2 DNFQKVEKIGEGTYGVVYKARNK---LTGEAVALKKIRLDTETEGVPSTAIREISLLRELN-HPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLIN-AEGAIKLADFGLARA 151
BLAST of cdc7-like protein vs. Ensembl Yeast
Match: CDC7 (DDK (Dbf4-dependent kinase) catalytic subunit; required for origin firing and replication fork progression in mitotic S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression; required for pre-meiotic DNA replication, meiotic DSB formation, recruitment of monopolin complex to kinetochores during meiosis I, regulation of meiosis-specific Ndt80p; mutation complemented by human CDC7 and DBF4 co-expression [Source:SGD;Acc:S000002175]) HSP 1 Score: 144.05 bits (362), Expect = 2.414e-38 Identity = 96/319 (30.09%), Postives = 159/319 (49.84%), Query Frame = 3
Query: 207 INDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEI-----------FALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDE-DHSDFGNEK-IAIKSIDSQNN-----MKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHG-CRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAA 1106
I + +++IDKIGEG+F++V+K + ++ K+ ALK P+RI NEL +L + G V L A RV+D + ++P+ H +F +Y + I I+ Y+ LL ALK VH IIHRD+KP NFL++ + LVDFGLA +++ D S + D+ ++ N S+ + M+ Q + ++ + + + + G LT + TR + R GT G+R PEV M+ Q+T +D W+VG+I+ L ++P F+ DD D L +++++ A
Sbjct: 29 IENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSSPQRIYNELNLLYIMTGSSRVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDLPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLVDFGLAEAQM--DYKSMISSQNDYDNYANTNHDGGYSMRNHEQFCPCIMRNQYSPNSHNQTPPMVTIQNGKVVHLNNVNGVDLTKGYPKNETRRIKRANRAGTRGFRAPEVLMKCGAQSTKIDIWSVGVILLSLLGRRFPMFQSLDDADSLLELCTIFGWKELRKCA 345
BLAST of cdc7-like protein vs. Ensembl Yeast
Match: CKA2 (Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]) HSP 1 Score: 77.411 bits (189), Expect = 3.750e-16 Identity = 52/150 (34.67%), Postives = 79/150 (52.67%), Query Frame = 3
Query: 216 NFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDP---KRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDY---YLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLA 647
N+EII+KIG G ++ VF R + K I ++ P K+I EL+IL + G NV+ L+ + D + F + IK +D+ Y + +I+ Y LL+AL + H I+HRDVKP N + D +K L+D+GLA
Sbjct: 49 NYEIINKIGRGKYSEVFSGRCI-------VNNQKCVIKVLKPVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIF-EEIKNVDFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLA 190
BLAST of cdc7-like protein vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]) HSP 1 Score: 65.4698 bits (158), Expect = 2.823e-12 Identity = 41/156 (26.28%), Postives = 85/156 (54.49%), Query Frame = 3
Query: 210 NDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDH--IKFIDYYLL------MDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHS 653
+ F+ ++K+G G++A V+K +K + + +K P E+ ++K++ +N+++L+ ++ + ++ F+D+ K++D + +++N ++ + LL L HENKI+HRD+KP N L + +R + L DFGLA +
Sbjct: 4 SSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELK-HENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLIN-KRGQLKLGDFGLARA 157
BLAST of cdc7-like protein vs. Ensembl Yeast
Match: SNF1 (AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]) HSP 1 Score: 66.6254 bits (161), Expect = 3.495e-12 Identity = 81/328 (24.70%), Postives = 131/328 (39.94%), Query Frame = 3
Query: 216 NFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPK---------RIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLL---MDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVF--------HSLIYFLSFEKMQAAAKDIQRRIIVNP 1139
N++I+ +GEGSF KV+ + ALK II+ K RIE E+ L+ + ++IKL+ + KD I M++ + + + DY + M E R + + ++ A+++ H +KI+HRD+KP N L D + DFGL++ I+++ N ++ SC G P+V G Y PE VD W+ G+I+ + L + PF D+ + V ++L FLS AA I+R +IVNP
Sbjct: 54 NYQIVKTLGEGSFG---KVKLAYHTTTGQKVALK----IINKKVLAKSDMQGRIEREISYLRLLR-HPHIIKLYDVIKSKDEIIMVIEYAGN-ELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHL-NVKIADFGLSN---------------------------------------------------IMTDGNFLKTSC----------GSPNYAAPEVISGKL--YAGPE-----------VDVWSCGVILYVMLCRRLPF--DDESIPVLFKNISNGVYTLPKFLS----PGAAGLIKRMLIVNP 291
BLAST of cdc7-like protein vs. Ensembl Yeast
Match: PKH1 (Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]) HSP 1 Score: 63.1586 bits (152), Expect = 4.510e-11 Identity = 42/149 (28.19%), Postives = 75/149 (50.34%), Query Frame = 3
Query: 216 NFEIIDKIGEGSFAAVF--KVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKF---IDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLA 647
+F+ +++G+GS+++V R + ++ + ++ I K + E L+K+ G K + KL F F+ + ++ L+ + H F I Y ++ R Y ++ A+ +H IIHRD+KP N L D+ K L DFG A
Sbjct: 124 DFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNM-KVKLTDFGTA 271
BLAST of cdc7-like protein vs. Ensembl Nematostella
Match: EDO33825 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR42]) HSP 1 Score: 209.149 bits (531), Expect = 8.684e-61 Identity = 131/387 (33.85%), Postives = 199/387 (51.42%), Query Frame = 3
Query: 168 NIRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKK------FTLVDFGLAHSEVHGDLGSWFD------------------DEDHSDFG------NEKIAIKSIDSQNNMKRQDT------GTLKSRLSDTSILSESNQIEASCICGNRL-TTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEK 1217
N + E + QF ++ D F ++ K+GEG+F+ V+ +K + E +ALK IP P+RIENEL+ L+ IGGK N+I + +R DHI ++P+ H KF DY L M + EIR+Y+RNL +ALK VH ++IHRDVKP+NFLY R+ K+ TLV GL++ + S D D+S G N + A++ + QN + + T G K++ S S S ++ C + C C +R H R GT G+R PEV ++ +QTTAVD W+ GI+ L+G+YPFF+ DD+ +I + + A D + ++++ K +KS CQ +R+ C K
Sbjct: 29 NSEAGELLTQFPELKDIFTVVSKVGEGTFSNVY--LAKMHDFPDEFWALKHIIPTSGPERIENELKCLQIIGGKDNIIGVEMTYRRNDHIVFVLPYFPHQKFQDYMLDMSVCEIREYIRNLFIALKRVHSFQVIHRDVKPSNFLYCRQSKRDLLAIVKTLVT-GLSNGKYKSTAISPKSSKLPTRRSTRLSPQIENKDLDYSATGATLSRANTRPALEPRNDQNIIFTRSTKNFKSPGATKTKKSSRSP-SRHGGVKPRCAVKHSPDEICATCISRAHQNTPRAGTPGFRSPEVLLKCPDQTTAVDIWSAGIVFLCALSGRYPFFRAQDDMTALAQIISLIGSSESIHVANDQGKDVVMSEK------CPTGSLKSACQRLRQGCSK 405
BLAST of cdc7-like protein vs. Ensembl Nematostella
Match: EDO41242 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z6]) HSP 1 Score: 76.6406 bits (187), Expect = 9.619e-16 Identity = 49/157 (31.21%), Postives = 85/157 (54.14%), Query Frame = 3
Query: 207 INDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFID------YYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFT--LVDFGLAHS 653
++ N+++++ IGEGSFA VF+ +K + L+ T + D ++IE E+ + K + +N++ L+ + R + + ++M +V D YY + R R LL AL+++H +I+HRD+KP+N L R T L DFGLA +
Sbjct: 1 MSPNYDMLELIGEGSFAKVFRCIERKTGLEFAAKELRLT-DVEDKEKIEQEIAVWKDLR-HENIVSLYSSIREGETVCLIMEYVAGGSLFDEVIQQTYY---SEKQARLVTRQLLNALEYLHSRRIVHRDIKPDNLLLKRTGNNVTIKLADFGLAQA 152
BLAST of cdc7-like protein vs. Ensembl Nematostella
Match: EDO35402 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLJ0]) HSP 1 Score: 72.0182 bits (175), Expect = 8.161e-14 Identity = 54/165 (32.73%), Postives = 85/165 (51.52%), Query Frame = 3
Query: 213 DNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIEN----ELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFID---YYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFD 686
+ +E + +GEGS+ V K R K +I A+K I D K ++ E+R+L+++ +N++ L FR K +F++ FVDH D Y +D N +R + +L A++ +H + IIHRDVKP N L R L DFG A + G ++ D
Sbjct: 2 EKYENLGLVGEGSYGMVMKCRHKDS---NQIVAIKKFIESEDDKMVKKIAMREVRMLRQLR-HENLVNLIEVFRRKKRLFLVFEFVDHTVLDDLERYPNGLDENTVRKVMWQVLRAIEFIHRHNIIHRDVKPENILVS-RSGIVKLCDFGFARTLASGQGEAYTD 161 HSP 2 Score: 47.3654 bits (111), Expect = 8.042e-6 Identity = 38/155 (24.52%), Postives = 58/155 (37.42%), Query Frame = 3
Query: 909 GTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSAYDLLSKLLEPKFHTRITCREALQHKFF 1373
T YR PE+ + T+ AVD WAVG ++A LTG+ P F D D+D + ++ F + I + +KN + + D + + A D+L L+ R TC + L H FF
Sbjct: 164 ATRWYRAPELLVGDTKYGRAVDVWAVGCLLAEMLTGE-PLFPGDSDIDQLYHIMR-----------------------------CFGNLISRHREIFQKNPLFVGMRLPDIKEVEPMERRFPRISPMAVDMLKLCLKMDPSERPTCAQLLNHDFF 288
BLAST of cdc7-like protein vs. Ensembl Nematostella
Match: EDO49898 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF52]) HSP 1 Score: 70.8626 bits (172), Expect = 3.410e-13 Identity = 52/175 (29.71%), Postives = 88/175 (50.29%), Query Frame = 3
Query: 189 VKQFSDINDNFEIIDKIGEGSFAAVFKV--RSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFV------DHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKK--FTLVDFGLAHSEVHGDLGSWF 683
+ + N+ +E+ +++G+G+F+ V K R KIE +I K + D ++E E RI + + NV++LH F++ V + I +YY D + ++ +L++++H HEN I+HRD+KP N L R + L DFGLA EV G+ W+
Sbjct: 7 ITEGGTFNEKYELKEELGKGAFSTVRKCCHRETKIEYAVKILDTK-NMTQRDVHKVEREARICRHLR-HPNVVRLHANIMSDGFYFLVFDLVTGGELFEDIVAREYYSEADASHC---IQQVLLSVQHCHENGIVHRDLKPENLLLASRERGAMVKLADFGLA-IEVDGERLGWY 175
BLAST of cdc7-like protein vs. Ensembl Nematostella
Match: EDO36034 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJR1]) HSP 1 Score: 69.3218 bits (168), Expect = 9.695e-13 Identity = 72/290 (24.83%), Postives = 122/290 (42.07%), Query Frame = 3
Query: 219 FEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPII--DPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFV---DHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGN--------------RLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFF 1031
FE I IG G+F V+ VR ML + L+ + ++ E IL + + V+KL+++F+ +++++ +M +V D + + + + + + Y+ L++A+ VH +HRD+KP+N L D + L DFGL W D + + G RQD+ R + ++ A+C CG+ R R + H V GT Y PEV +R + D W+VG+I+ L G+ PF
Sbjct: 38 FEKIRTIGIGAFGEVWLVRKTDTSMLYAMKILRKSEVFRRNQAAHVKAERDILAE-ADNEWVVKLYYSFQDQENLYFVMDYVPGGDLMSLLIKFGIFPEDYAKFYIAELVLAIDSVHRMGFVHRDIKPDNILID-KDGHIKLTDFGLCTG------FRWTHDSKYYEKGQH-------------MRQDSMEPDERAWE--------EMRATCHCGDISIDKPYSEMKPLERRHFRKHMRCQAHSLV---GTPNYIAPEVLLR-IGYRQSCDWWSVGVILYEMLVGQPPFL 294
BLAST of cdc7-like protein vs. Ensembl Medaka
Match: cdc7 (cell division cycle 7 [Source:NCBI gene;Acc:101159611]) HSP 1 Score: 208.764 bits (530), Expect = 1.484e-61 Identity = 141/458 (30.79%), Postives = 210/458 (45.85%), Query Frame = 3
Query: 192 KQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIG-GKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHG-----------DLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKS-RLSDTS-----ILSESNQ-----IEASCICGNRLT--TCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLP---------------------LIGAFNDWIKSRC------------------QFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSAYDLLSKLLEPKFHTRITCREALQHKFF 1373
K + F I+DKIGEG+F++V+ ++ + KE+FALK IP P RI EL+ L G G++NV+ + + FR DH+ ++MP+++H + I + E+R Y+ +LL AL+H+H+ IIHRD+KPNNFLY+RR + LVDFGLA L K K+ + TG L RLS S LS S+Q ++ C LT C+ C +R R GT G+R PEV + +Q TA+D W+ G+I+ L+G+YPFFK DDL ++ + AAK + ++ + + P + A D ++R Q +CE+ L+K N + + D AY LL +LL+ +TRI+ EALQH F
Sbjct: 21 KAVPQLATAFNILDKIGEGTFSSVYLGEARMRDGRKELFALKHLIPTSHPTRIAAELQCLTAAGCGRENVMGVTYCFRRDDHVVIVMPYMEHREIIGS---LSFAEVRLYVYHLLKALRHIHQFGIIHRDIKPNNFLYNRRSGVYALVDFGLAQGTADTKIELLKVVRPRPLQKGGGSAPQRSRAPPKPFSKTTSGSLPAPPRQTGALPPWRLSSASRAAGRTLSSSSQKPQRAVQPGLTCDCFLTDRVCNICMSRKQQVAPRAGTPGFRAPEVLTKCPDQGTAIDVWSAGVILLSLLSGRYPFFKAGDDLTALAQIMTVRGSRETIRAAKTFGKAVVCSQELPPQDLRTLCETLRGRRRSSTGEGVPPAMADACRNRMDGASARGPADAAEPSLQKQESLSSCERTESLVKPNLEAEEEVEDWDRVPDEAYHLLDRLLDLNPNTRISAAEALQHPLF 475
BLAST of cdc7-like protein vs. Ensembl Medaka
Match: camk1gb (calcium/calmodulin-dependent protein kinase type 1D [Source:NCBI gene;Acc:101164726]) HSP 1 Score: 83.9593 bits (206), Expect = 4.032e-17 Identity = 73/293 (24.91%), Postives = 122/293 (41.64%), Query Frame = 3
Query: 186 YVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPK-----RIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLR---NLLVALKHVHENKIIHRDVKPNNFLYDRRRK--KFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFK 1034
+ K +I + F++++++G G+F+ VF VR +K KF + I K +ENE+ +L++I +NV+ L + + H +++M V + D L + +D R +L A+ ++H+N I+HRD+KP N LY + + K + DFGL S+++DT I+S T C GT GY PEV + + AVD W++G+I I L G PF++
Sbjct: 10 WKKSTENIQEIFDLMEELGSGAFSEVFMVRERKT-------GKKFAMKCIKKKKKRDINLENEMAVLRRIK-HENVVGLEDIYESRTHYYLIMQLVSGGELFDRILDRGMYTEKDASRVIQQVLQAVSYLHQNGIVHRDLKPENILYYSQDEDSKIMISDFGL----------------------------------------------SKMTDTGIMS---------------TAC--------------GTPGYVAPEV-LAQKPYSKAVDCWSIGVITYILLCGYPPFYE 218
BLAST of cdc7-like protein vs. Ensembl Medaka
Match: ENSORLT00000012877.2 (calcium/calmodulin-dependent protein kinase type 1D [Source:NCBI gene;Acc:101157124]) HSP 1 Score: 81.6481 bits (200), Expect = 2.297e-16 Identity = 54/172 (31.40%), Postives = 89/172 (51.74%), Query Frame = 3
Query: 177 SVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLR---NLLVALKHVHENKIIHRDVKPNNFLY--DRRRKKFTLVDFGLAHSEVHGDLGS 677
+ + K S+I D F+ K+G GSF+ VF VR KK L + LK + +ENE+ IL++I +NV+ L + + H +++M V + D L + +D R +L A+ ++H+N I+HRD+KP N L+ K + DFGL+ + HG + +
Sbjct: 7 TCSWKKSTSNIKDVFDFEGKMGSGSFSEVFMVREKKTGRLYALKCLKKKH--LAHSNLENEINILRRIK-HENVVGLEDFYESRTHYYLVMQLVSGGELFDRILDKGVYTEKDASRVIKQVLQAVSYLHQNSIVHRDLKPENLLFFNTDENAKIMVSDFGLSKTPEHGVMST 175
BLAST of cdc7-like protein vs. Ensembl Medaka
Match: camk1da (calcium/calmodulin dependent protein kinase ID [Source:NCBI gene;Acc:101162588]) HSP 1 Score: 73.9442 bits (180), Expect = 7.423e-14 Identity = 54/176 (30.68%), Postives = 91/176 (51.70%), Query Frame = 3
Query: 186 YVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPK----RIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFID------YYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLY--DRRRKKFTLVDFGLAHSEVHGDLGS 677
+ KQ DI F+ + +G G+F+ V + K + +FA+K IP K IENE+ +L+KI +N++ L + DH++++M V + D +Y D + + +R +L A+ ++H+ I+HRD+KP N LY + K + DFGL+ E GD+ S
Sbjct: 14 WKKQVDDIKKIFDFKEVLGTGAFSEVVLAQEK---LSGRMFAVK-CIPKKALKGKESSIENEIAVLRKIK-HENIVALEDIYESPDHLYLIMQLVSGGELFDRIVEKGFYTEKDASTL---IRQVLDAVNYLHKLGIVHRDLKPENLLYFNPQDESKIMISDFGLSKMEGSGDVMS 181
BLAST of cdc7-like protein vs. Ensembl Medaka
Match: rps6kal (highly divergent homeobox [Source:NCBI gene;Acc:101174679]) HSP 1 Score: 72.7886 bits (177), Expect = 3.089e-13 Identity = 46/158 (29.11%), Postives = 83/158 (52.53%), Query Frame = 3
Query: 216 NFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKF----TIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFV---DHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGD 668
FE++ +G+GSF VF VR +++A+K ++ + D R + E IL ++ ++KLH+AF+ + +++++ F+ D + ++ +++ YL L +AL H+H I++RD+KP N L D L DFGL+ V D
Sbjct: 110 QFELLKVLGQGSFGKVFLVRKLVGPDASQLYAMKVLKKASLKVRDRVRTKMERDILVEVN-HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIVYRDLKPENILLD-EAGHIKLTDFGLSKESVDAD 265
BLAST of cdc7-like protein vs. Planmine SMEST
Match: SMESG000069572.1 (SMESG000069572.1) HSP 1 Score: 839.336 bits (2167), Expect = 0.000e+0 Identity = 406/406 (100.00%), Postives = 406/406 (100.00%), Query Frame = 3
Query: 159 TTINIRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSAYDLLSKLLEPKFHTRITCREALQHKFFN 1376
TTINIRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSAYDLLSKLLEPKFHTRITCREALQHKFFN
Sbjct: 13 TTINIRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGDLGSWFDDEDHSDFGNEKIAIKSIDSQNNMKRQDTGTLKSRLSDTSILSESNQIEASCICGNRLTTCHGCRTRPHPQVRRGGTVGYRPPEVTMRHTEQTTAVDTWAVGIIMAIFLTGKYPFFKVDDDLDVFHSLIYFLSFEKMQAAAKDIQRRIIVNPKPLPLIGAFNDWIKSRCQFIRKNCEKITKLIKDNSDKNCIYGNHAEFDDSAYDLLSKLLEPKFHTRITCREALQHKFFN 418
BLAST of cdc7-like protein vs. Planmine SMEST
Match: SMESG000024545.1 (SMESG000024545.1) HSP 1 Score: 74.7146 bits (182), Expect = 1.896e-14 Identity = 51/148 (34.46%), Postives = 82/148 (55.41%), Query Frame = 3
Query: 213 DNFEIIDKIGEGSFAAVFK-VRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFR--VKDHIFMLMPFVDHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLA 647
D+++I+ KIG G ++ VF +R E +K P+ K I+ E++IL+ + G N+I L R + + ++ +VD+ F D Y + +IR Y+ LL AL H I+HRDVKP+N + D +R+K L+D+GLA
Sbjct: 35 DDYQIVRKIGRGKYSEVFAGIRFST----NEEVVIKVLKPVKKDK-IKREIKILQNLKGCINIITLEDIVRDPMSNTPALIFEYVDNTDFKDLYPTLSDYDIRFYIFELLKALNCCHSMGIMHRDVKPHNVMIDHQRRKLRLIDWGLA 177
BLAST of cdc7-like protein vs. Planmine SMEST
Match: SMESG000042100.1 (SMESG000042100.1) HSP 1 Score: 72.0182 bits (175), Expect = 1.558e-13 Identity = 45/147 (30.61%), Postives = 80/147 (54.42%), Query Frame = 3
Query: 219 FEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYLLMDINEIRDY---LRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKK-FTLVDFGLA 647
+EI++KIG GS V+ K+ ++ FA K ++ K I++E+ +L K+ N+I+L+ + + M++ +V + D + +D +R +L A+ ++HEN IIHRD+KP N LY+ + + L DFG+A
Sbjct: 19 YEILNKIGNGSTCTVYCCVRKRTDIK---FAAKVISKKVNKKLIKSEVGVLLKLT-HPNIIRLYEVYESATDVHMVLEYVSGGELFDRIVSRGFYSEKDASRCVREMLQAVSYLHENDIIHRDLKPENLLYESQEESNLKLADFGIA 161
BLAST of cdc7-like protein vs. Planmine SMEST
Match: SMESG000059433.1 (SMESG000059433.1) HSP 1 Score: 72.0182 bits (175), Expect = 3.887e-13 Identity = 46/160 (28.75%), Postives = 84/160 (52.50%), Query Frame = 3
Query: 210 NDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKF----TIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFV---DHIKFIDYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSEVHGD 668
+ +FE++ +G+GSF VF VR ++A+K ++ + D KR + E IL I ++ LH+AF+ + +++++ F+ D + + ++++ YL L +AL H+H I++RD+KP N L D L DFGL+ ++ D
Sbjct: 50 SSHFELLRVLGQGSFGKVFLVRKVSEPQQGILYAMKVLKKASLKVQDRKRTKMERDILAAIR-HPFIVTLHYAFQNEGKVYLILEFLKGGDLFSRLSKEFMFTEDDVKFYLAELALALDHLHSLGIVYRDLKPENILLD-EDGHIKLTDFGLSKESIYND 207 HSP 2 Score: 55.8398 bits (133), Expect = 5.282e-8 Identity = 36/162 (22.22%), Postives = 78/162 (48.15%), Query Frame = 3
Query: 195 QFSDINDNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKR--IENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFVDHIKFIDYYL---LMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLY---DRRRKKFTLVDFGLAHSE 656
+F ++ + + ++IG+GSF+ ++ K + + I +ID + + E+ IL + G +++KL + ++ + ++M +++ + + L E L L + ++H N ++HRD+KP+N LY D + + DFG A +
Sbjct: 403 KFQKVDHYYTLKEEIGKGSFSVCYRAVHKTT-------GVNYAIKVIDGTKRDVIEEVEILFRFGAHPHIVKLKEVYVQQNTVSLIMEYLEGGELLTNILSQKYFSEKEASKILYVLTETVHYLHTNLVVHRDLKPSNILYSKKDTNPENLVICDFGFAKQQ 557
BLAST of cdc7-like protein vs. Planmine SMEST
Match: SMESG000023149.1 (SMESG000023149.1) HSP 1 Score: 70.4774 bits (171), Expect = 1.043e-12 Identity = 42/151 (27.81%), Postives = 80/151 (52.98%), Query Frame = 3
Query: 213 DNFEIIDKIGEGSFAAVFKVRSKKIEMLKEIFALKFTIPIIDPKRIENELRILKKIGGKKNVIKLHFAFRVKDHIFMLMPFV--DHIKFI-DYYLLMDINEIRDYLRNLLVALKHVHENKIIHRDVKPNNFLYDRRRKKFTLVDFGLAHSE 656
+++ +DK+G+G++A VFK RS+ E L + ++ P E+ +L+ + NV+ LH + ++ ++ D +++ D +M +N ++ +L +L L + H +I+HRD+KP N L + R L DFGLA ++
Sbjct: 277 ESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLH-HANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAK 426 The following BLAST results are available for this feature:
BLAST of cdc7-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of cdc7-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of cdc7-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of cdc7-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of cdc7-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of cdc7-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of cdc7-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of cdc7-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of cdc7-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of cdc7-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of cdc7-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of cdc7-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of cdc7-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of cdc7-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008000 ID=SMED30008000|Name=cdc7-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1404bpback to top protein sequence of SMED30008000-orf-1 >SMED30008000-orf-1 ID=SMED30008000-orf-1|Name=SMED30008000-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=421bp MSSVSENSENVNTTINIRSVEYVKQFSDINDNFEIIDKIGEGSFAAVFKVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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