DNA-binding regulatory protein, YebC/PmpR family

Overview
NameDNA-binding regulatory protein, YebC/PmpR family
Smed IDSMED30007862
Length (bp)962
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of DNA-binding regulatory protein, YebC/PmpR family (SMED30007862) t-SNE clustered cells

Violin plots show distribution of expression levels for DNA-binding regulatory protein, YebC/PmpR family (SMED30007862) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DNA-binding regulatory protein, YebC/PmpR family (SMED30007862) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DNA-binding regulatory protein, YebC/PmpR family (SMED30007862) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30007862

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
muscle cellSMED30007862SMESG000039610.1 dd_Smed_v4_2722_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Human
Match: TACO1 (translational activator of cytochrome c oxidase I [Source:HGNC Symbol;Acc:HGNC:24316])

HSP 1 Score: 86.6557 bits (213), Expect = 6.294e-19
Identity = 72/249 (28.92%), Postives = 125/249 (50.20%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLN---AIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDPYFI-EFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIA--CKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINVE 943
            AGH+ W  V+  K  KD ++S    I ++L LN   A+KEG    +P+ N+ LA +++  ++ ++P ST+E  L      D Y + E + PGG  L++E+ +  + K + DI  ++ K G      +    +F  KG I    +       N + ALEMA+E GAE+V  E + E E +V+KFIC+   L  V+  L    +  +       P +K+++          +I  + N+ + +H ++ N+E
Sbjct:   58 AGHNKWSKVRHIKGPKDVERS---RIFSKLCLNIRLAVKEGG--PNPEHNSNLANILEVCRSKHMPKSTIETALKMEKSKDTYLLYEGRGPGGSSLLIEALSNSSHKCQADIRHILNKNGGVMAVGA--RHSFDKKGVIVVEVEDREKKAVNLERALEMAIEAGAEDV-KETEDEEERNVFKFICDASSLHQVRKKLDSLGLCSVSCALEFIPNSKVQLAEPDLEQAAHLIQALSNHEDVIH-VYDNIE 297
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Celegans
Match: taco-1 (Translational Activator of Cytochrome c Oxidase [Source:UniProtKB/TrEMBL;Acc:Q965T4])

HSP 1 Score: 85.1149 bits (209), Expect = 6.927e-19
Identity = 69/248 (27.82%), Postives = 115/248 (46.37%), Query Frame = 2 
Query:  209 RQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLL--LKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKY-GFKSCPNSILNAAFKYKGEIACKPNSSG-LNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINV 940
            +Q GHS WQN+K  K   D  +S     L R V  A+  G    D K+N +LA +    +A  +P+ TL+  L  +K+     Y  +   P GIFL+V +   +      D+     K  GF+   +  + + F+ KG +       G + N +E  E+ LE  AEEVL  L  E     ++ IC+   L+ +++ L +    I+ SE    P++ I      +  V ++   ++ + E V +IF N+
Sbjct:   39 QQKGHSKWQNIKAVKGKNDLIRSKATNFLLRKVRGAVSRGG--FDMKLNRELADLESEFRAQGLPLDTLKNFLQKMKDKPEVEYSFDIIGPSGIFLIVTAETSNKKAFENDLRKYFNKLGGFRLAADGGVRSWFEEKGVVHVDTKKGGKILNIEEMEEIGLEFDAEEVL--LIEEDSTKKFELICDAKSLQTLENGLGKGGFSILQSEIEFRPVHPIDCPEAEEPKVQKLYEMLQED-EQVRQIFDNI 281
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Fly
Match: CG4957 (gene:FBgn0032205 transcript:FBtr0079985)

HSP 1 Score: 80.4925 bits (197), Expect = 2.273e-17
Identity = 69/251 (27.49%), Postives = 126/251 (50.20%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDI----IDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNN----EDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINVE 943
            AGHS W N+K TK  KD  +++    ++R +  AI+EG+   DP IN+ L   I+RA   N+P  T++  L K       +  Y ++ +    ++L+      + +  + D   ++KK G +      + + F+  G I  + +++ L N    ED+A   A+E+GAEE+  E+    + SV  F+C+P+ L ++   L +    +  SE+   P+N +++    +   D  + K+R N   +  I+ NVE
Sbjct:    2 AGHSKWANIKHTKALKDGARAALFAKISRQIRMAIQEGNSA-DPAINSLLRTEIERALKQNMPSGTIQNTLNKFKASKVQLKKYRLDIKYKRNVYLICIFYTDNFSGVKMDATPMIKKAGGEFMD---VGSLFEDFGLIETRYDTAKLQNESSLEDKATNDAIELGAEEI--EVVDNVDGSV-NFLCSPVVLTSLSRNLEKAGYTVENSEHIFSPMNVVQLSPEEQKTYDVFVEKLR-NLPGLEDIYDNVE 244
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Zebrafish
Match: taco1 (translational activator of mitochondrially encoded cytochrome c oxidase I [Source:NCBI gene;Acc:570857])

HSP 1 Score: 80.4925 bits (197), Expect = 4.303e-17
Identity = 57/193 (29.53%), Postives = 103/193 (53.37%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLL--LKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSAL 787
            AGH+ W  VK  K  KD  ++      T ++  A++EG    +P++N  LA ++++ +  N+P +T+E  L   K+     Y  E   PGG  +++E    +  +   ++  ++ K G      +  N  F  KG +A   +  G+++E +ALE+A+E GAE+V  E++ E +  + +FIC+   +K V+SAL
Sbjct:   34 AGHNKWSKVKDIKIPKDAARARVIAKYTMMIRIAVREGGP--NPELNVGLAQILEQCRNKNLPKTTIEGALKGAKSKPGVQYLYEATGPGGCKILIEVLTDNNMRSLNEVKRIMTKNGGALREGARRN--FDRKGVVAA--SRDGISSE-KALELAIEAGAEDVQ-EMEDEEDRPILQFICDMTSMKAVRSAL 218
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Zebrafish
Match: taco1 (translational activator of mitochondrially encoded cytochrome c oxidase I [Source:ZFIN;Acc:ZDB-GENE-070410-35])

HSP 1 Score: 80.4925 bits (197), Expect = 4.795e-17
Identity = 57/193 (29.53%), Postives = 103/193 (53.37%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLL--LKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSAL 787
            AGH+ W  VK  K  KD  ++      T ++  A++EG    +P++N  LA ++++ +  N+P +T+E  L   K+     Y  E   PGG  +++E    +  +   ++  ++ K G      +  N  F  KG +A   +  G+++E +ALE+A+E GAE+V  E++ E +  + +FIC+   +K V+SAL
Sbjct:   34 AGHNKWSKVKDIKIPKDAARARVIAKYTMMIRIAVREGGP--NPELNVGLAQILEQCRNKNLPKTTIEGALKGAKSKPGVQYLYEATGPGGCKILIEVLTDNNMRSLNEVKRIMTKNGGALREGARRN--FDRKGVVAA--SRDGISSE-KALELAIEAGAEDVQ-EMEDEEDRPILQFICDMTSMKAVRSAL 218
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Zebrafish
Match: taco1 (translational activator of mitochondrially encoded cytochrome c oxidase I [Source:ZFIN;Acc:ZDB-GENE-070410-35])

HSP 1 Score: 80.4925 bits (197), Expect = 7.982e-17
Identity = 57/193 (29.53%), Postives = 103/193 (53.37%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLL--LKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSAL 787
            AGH+ W  VK  K  KD  ++      T ++  A++EG    +P++N  LA ++++ +  N+P +T+E  L   K+     Y  E   PGG  +++E    +  +   ++  ++ K G      +  N  F  KG +A   +  G+++E +ALE+A+E GAE+V  E++ E +  + +FIC+   +K V+SAL
Sbjct:   70 AGHNKWSKVKDIKIPKDAARARVIAKYTMMIRIAVREGGP--NPELNVGLAQILEQCRNKNLPKTTIEGALKGAKSKPGVQYLYEATGPGGCKILIEVLTDNNMRSLNEVKRIMTKNGGALREGARRN--FDRKGVVAA--SRDGISSE-KALELAIEAGAEDVQ-EMEDEEDRPILQFICDMTSMKAVRSAL 254
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Zebrafish
Match: taco1 (translational activator of mitochondrially encoded cytochrome c oxidase I [Source:ZFIN;Acc:ZDB-GENE-070410-35])

HSP 1 Score: 80.4925 bits (197), Expect = 8.060e-17
Identity = 57/193 (29.53%), Postives = 103/193 (53.37%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLL--LKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSAL 787
            AGH+ W  VK  K  KD  ++      T ++  A++EG    +P++N  LA ++++ +  N+P +T+E  L   K+     Y  E   PGG  +++E    +  +   ++  ++ K G      +  N  F  KG +A   +  G+++E +ALE+A+E GAE+V  E++ E +  + +FIC+   +K V+SAL
Sbjct:   70 AGHNKWSKVKDIKIPKDAARARVIAKYTMMIRIAVREGGP--NPELNVGLAQILEQCRNKNLPKTTIEGALKGAKSKPGVQYLYEATGPGGCKILIEVLTDNNMRSLNEVKRIMTKNGGALREGARRN--FDRKGVVAA--SRDGISSE-KALELAIEAGAEDVQ-EMEDEEDRPILQFICDMTSMKAVRSAL 254
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Xenopus
Match: TACO1 (translational activator of mitochondrially encoded cytochrome c oxidase I [Source:NCBI gene;Acc:100135399])

HSP 1 Score: 79.7221 bits (195), Expect = 2.193e-16
Identity = 73/303 (24.09%), Postives = 149/303 (49.17%), Query Frame = 2 
Query:   71 STIYTVILNKI------YMIRTVFFNKLSIKSLY-KIENSLQFSFNSILKSNTRQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDP---YFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPN--SSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINVE 943
            + I +++L++I      +  R++ F +  +   +  +  S +  F++ L      AGH+ W  VK  K  KD  ++     L+ ++  A++EG    +P +N  L+ +I++ +  N+P +++E  +   D   P      E + PGG  L++E    +  +   ++  ++ K G   C  +    +F+ KG +  + +    G    ++ALE+A+E GAE+V  E D E ++ +YK+IC+   L+ V+S+LS   +  I S     P   +++ +        ++  I N+ E + R++ N+E
Sbjct:   12 ARIMSLVLSRICSAHRKHAFRSLLFCQEPLGRWFLPVVASQETYFHTSL---MMSAGHNKWSKVKHIKGPKDEARARVFAKLSMMIKVAVREGG--PNPDLNMALSQLIEQCRERNMPKTSIEAAIKGADKAKPSACVLYEGRGPGGASLLIELLTDNNNRSYAEVKLLMGKNGGVMCDGA--RHSFEKKGVVTVRTHDKDGGDVPLEKALELAIEAGAEDVQEEQDEEDKD-IYKYICDIPSLREVRSSLSSFGLVPISSGPEFRPKTTVQLSNTDIEQASHLLDLINNHPEVI-RVYDNIE 305
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Mouse
Match: Taco1 (translational activator of mitochondrially encoded cytochrome c oxidase I [Source:MGI Symbol;Acc:MGI:1917457])

HSP 1 Score: 82.0333 bits (201), Expect = 1.954e-17
Identity = 69/249 (27.71%), Postives = 120/249 (48.19%), Query Frame = 2 
Query:  200 SNTRQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDPYFI-EFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINVE 943
            S T  AGH+ W  V+  K  KD ++S   + LT  +  A+KEG    +P+ N+ LA +++  ++ N+P ST+E  L        Y + E + PGG  L++E+ +    K   DI  ++ K G      +      K    +  +       N + ALE+A+E GAE+V  E + E E++++KFIC+   L  V+  L    +  +       P +K+++          +I  + NN+E V  ++ N+E
Sbjct:   50 SATASAGHNKWSKVRHIKGPKDMERSRIFSKLTLSIRLAVKEGG--PNPENNSSLANILELCRSKNMPKSTIESALKTEKNKGIYLLYEGRGPGGSSLLIEALSNSGPKCHLDIKYILNKNGGMMAEGARHFFDKKGVVVVGVEDREKKAVNLERALELAIEAGAEDVK-EAEDEEEKNLFKFICDASSLHQVRKKLDSLGLCPVSCSMEFIPHSKVQLAEPELEQAAHLIQAL-NNYEDVIHVYDNIE 294
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. UniProt/SwissProt
Match: sp|Q8RAR7|Y1135_CALS4 (Probable transcriptional regulatory protein TTE1135 OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=TTE1135 PE=3 SV=2)

HSP 1 Score: 90.5077 bits (223), Expect = 5.232e-20
Identity = 68/249 (27.31%), Postives = 120/249 (48.19%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLL------LKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINVE 943
            AGHS W N+K  K+  D +K    T LT+ ++ A KEG G  DP+ N+KL   I+RAKA N+P   +++ +      L    ++    E   P G  ++VE+   +  +   +I  +  + G        +   F   G I  +   S   NE++ + +A+E GAE      D   +E  ++ I +P + + V+ A+ +   +I  +E  + P N IK+        +++I K+ +N + V  ++ NVE
Sbjct:    2 AGHSKWANIKHKKEKMDAKKGRIFTKLTKDIIKAAKEGGG--DPETNSKLKLAIERAKAFNLPSENIQRAIKRGTGELGGAKLEEVIYEGYGPAGTAIIVEALTDNKNRTAGEIRHIFDRNGGTLGAAGSVTWMFDKVGVIVVEKTDS--INEEDLMMVAIEAGAE------DFSADEGEFEIITDPSNFQEVREAIEKAGYKISEAEITMLPKNTIKLSPEDYEKFEKLIDKLEDN-DDVQNVYHNVE 239
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. UniProt/SwissProt
Match: sp|B8CXG6|Y1235_HALOH (Probable transcriptional regulatory protein Hore_12350 OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) OX=373903 GN=Hore_12350 PE=3 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 1.303e-19
Identity = 60/220 (27.27%), Postives = 112/220 (50.91%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLL------LKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIE 856
            AGHS W N+K  K  +DR++    + L++++  A +EG G  DP++N  L   I +AK  N+P   +E+ +      L+    + +  E   PGG+ L +E  + +  +   +I  V+ K G     +  ++  FK +G++    N S   +EDE +  ALE GAE+V+      TE+++     +P D + V+  L E+ ++   ++  + P N + ++
Sbjct:    2 AGHSKWANIKHKKAKEDRKRGKLFSKLSKMITVAAREGGG--DPEMNPDLRLAIQKAKDNNMPNDNIERAIKRGTGELEGVKYEKFVYEGYGPGGVALYLELMSDNRNRTAAEIRHVLSKNGGNLGESGCVSWMFKRRGQLIVDLNESDF-DEDELMLEALEAGAEDVV------TEDNLLTIYTDPSDFEEVRKQLEEQGIKFSSADIAMVPENNVNVD 212
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. UniProt/SwissProt
Match: sp|C5CGU7|Y1935_KOSOT (Probable transcriptional regulatory protein Kole_1935 OS=Kosmotoga olearia (strain ATCC BAA-1733 / DSM 21960 / TBF 19.5.1) OX=521045 GN=Kole_1935 PE=3 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 4.077e-19
Identity = 68/249 (27.31%), Postives = 124/249 (49.80%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLK--NDIIDPYFI----EFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINVE 943
            +GH+ W N+K  K ++D +KS   T + R ++ A +EG    DP  N  L A I+RAKA N+P  T+EK + K   ++    F+    E  APGG+ +++ +   +  +   +I  ++ K+G     +  +   F+ KG I   P S  +++ DE   +A++ GAE++      + EE   + I  P +  NV++AL E      Y   Y+ P N + +       + +++  + +N + V  ++ N E
Sbjct:    2 SGHNKWANIKHRKMAQDAKKSKIFTKIIRELMVAAREGG--TDPNTNNALRAAIERAKAANMPKDTMEKAIKKGAGELEGQSFVEALYEVYAPGGVAMLIRALTDNKNRTAQEIRHLLSKHGGNMAESGSVAWMFERKGVITV-PRSE-ISDMDEFQLLAIDAGAEDI------QDEEDPVRIITAPEEASNVKNALEENGYTASYELTYI-PKNTVSVSGNDAEKLLKLLNVLEDN-DDVQEVYANFE 238
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. UniProt/SwissProt
Match: sp|A1W753|Y1898_ACISJ (Probable transcriptional regulatory protein Ajs_1898 OS=Acidovorax sp. (strain JS42) OX=232721 GN=Ajs_1898 PE=3 SV=1)

HSP 1 Score: 86.6557 bits (213), Expect = 1.306e-18
Identity = 66/254 (25.98%), Postives = 115/254 (45.28%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPM-----------STLEKLLLKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINVE 943
            AGHS W N++  K  +D ++    T + R +  A + G G  DP  N +L   ID+AKA N+P             TLE +  +    + Y I     GG  ++V++   +  +   ++     KYG        +   FK  G+I   P +S    ED+ +E+ALE GAE+V+ +     +E   + +  P D + V+ AL    ++   +E  + P N I +E      + +++  I  + + V  ++ N E
Sbjct:    2 AGHSKWANIQHRKGRQDEKRGKIWTRIIREITVAARTGGG--DPSANPRLRLAIDKAKAANMPADRIKYNIDKASGTLEGVSYEEIRYEGYGI-----GGAAIIVDTMTDNRVRTVAEVRHAFSKYGGNMGTEGSVAFQFKNVGQIIFAPGTS----EDKVMEVALEAGAEDVITD-----DEGAIEVLTAPGDFEAVRDALGAAGLQPEVAEVTMRPENTIALEGDDVARMQKLLDMI-EDLDDVQEVYHNAE 238
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. UniProt/SwissProt
Match: sp|Q3A233|Y2335_PELCD (Probable transcriptional regulatory protein Pcar_2335 OS=Pelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1) OX=338963 GN=Pcar_2335 PE=3 SV=1)

HSP 1 Score: 86.6557 bits (213), Expect = 1.699e-18
Identity = 68/249 (27.31%), Postives = 119/249 (47.79%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLK--NDIIDPYF----IEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINVE 943
            AGHS W N+K  K ++D ++    T L + +  A K G G  D + N +L   +D+AK  N+P   +E+ + K   D+    +     E   PGG+ ++VE    + T+   D+     K+G     +  +   F  KG+I    NS    + ++  E+ALE GAE+V        E+ V + I  P D + V++ L+E+ +    +E  + P N   +E     ++ +MI  + +N + V  +F N +
Sbjct:    2 AGHSKWANIKHRKGAQDAKRGKIFTKLIKEITVAAKIGGG--DLEANARLRLAVDKAKQANMPKDNIERAIKKGTGDLDGVTYEEGTFEGYGPGGVAVIVEFMTDNRTRTVADVRHSFNKFGGSLGVSGSVAFMFDRKGQIIFGENS----DFEKIFEVALEAGAEDV------NDEDGVTEVITAPADFETVRNTLAEQGLTPESAEVTMIPQNMTAVEGKQAESLMKMIDMLEDN-DDVQNVFANFD 237
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. TrEMBL
Match: A0A1S8WMH1 (DNA-binding regulatory protein, YebC/PmpR family OS=Opisthorchis viverrini OX=6198 GN=X801_08527 PE=4 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 2.038e-53
Identity = 101/247 (40.89%), Postives = 149/247 (60.32%), Query Frame = 2 
Query:  209 RQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNS--SGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALS-ERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINV 940
            R AGHSHWQNV+ TK+++D+QKS  A I  R V NAIK G GIRDPK+N++LA+V+  AKA +VP+STLE+ +      DPYFIE QAPGG+F+++ESC K    ER  I  +VK+YG    P   +   F  +    C P S  S L + D A    +++GA +V  E  +   +  +KF C+P +++ ++  L  +  ++ +  E+ L P  K++++S    N+ EM  +IR+  E V RI  NV
Sbjct:   40 RFAGHSHWQNVRHTKEARDKQKSKAAQIYIRAVNNAIKAGGGIRDPKLNSQLASVLAEAKANSVPLSTLERFMKAEFTTDPYFIEVQAPGGLFILIESCAKSVNAERHQIAGIVKRYGCSISPAGKIANEFFDRLAWVCVPGSPASNLTDLDAATNFGIDIGANDV--EEVTVDGQIAFKFYCDPSNVEQMRLLLERDHAIQPVSVEDVLVPKCKVQVDSKAYANLLEMYERIRDQHEYVDRIVDNV 284
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. TrEMBL
Match: A0A075AHL2 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_13255 PE=4 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 4.141e-53
Identity = 101/247 (40.89%), Postives = 149/247 (60.32%), Query Frame = 2 
Query:  209 RQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNS--SGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALS-ERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINV 940
            R AGHSHWQNV+ TK+++D+QKS  A I  R V NAIK G GIRDPK+N++LA+V+  AKA +VP+STLE+ +      DPYFIE QAPGG+F+++ESC K    ER  I  +VK+YG    P   +   F  +    C P S  S L + D A    +++GA +V  E  +   +  +KF C+P +++ ++  L  +  ++ +  E+ L P  K++++S    N+ EM  +IR+  E V RI  NV
Sbjct:   40 RFAGHSHWQNVRHTKEARDKQKSKAAQIYIRAVNNAIKAGGGIRDPKLNSQLASVLAEAKANSVPLSTLERFMKAEFTTDPYFIEVQAPGGLFILIESCAKSVNAERHQIAGIVKRYGCSISPAGKIANEFFDRLAWVCVPGSPASNLTDLDAATNFGIDIGANDV--EEVTVDGQIAFKFYCDPSNVEQMRLLLERDHAIQPMSVEDVLVPKCKVQVDSKAYANLLEMYERIRDQHEYVDRIVDNV 284
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. TrEMBL
Match: H2KRE6 (Putative transcriptional regulatory protein OS=Clonorchis sinensis OX=79923 GN=CLF_106110 PE=4 SV=1)

HSP 1 Score: 183.341 bits (464), Expect = 2.832e-52
Identity = 98/254 (38.58%), Postives = 152/254 (59.84%), Query Frame = 2 
Query:  188 SILKSNTRQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPN--SSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALS-ERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINV 940
            ++     R AGHSHWQNV+ TK+++D+QKS  + I  R V NAIK G G+RDPK+N++LA+V+  AKA +VP+STLE+ +      DPYFIE QAPGG+F+++ESC K    ER  I  +VK+YG    P   + + F  +    C P   +S L + D A +  +++GA +V  E  +   +  +KF C+P ++  ++  L  +  ++ +  E+ L P  K++++S    N+ EM  +IR+  E V RI  NV
Sbjct:   33 AVFTEARRFAGHSHWQNVRHTKEARDKQKSKASQIYIRAVNNAIKAGGGVRDPKLNSQLASVLAEAKANSVPLSTLERFIKAEFTTDPYFIEVQAPGGLFILIESCAKSVNSERHQIAGLVKRYGCSISPAGKIASEFFDRLAWICVPGGPASKLTDLDAATDFGIDIGANDV--EEVTVDGQIAFKFYCDPSNVDQMRLLLERDHAIQPMSVEDVLVPKCKVQVDSKAYANLLEMYERIRDQHEYVDRIIDNV 284
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. TrEMBL
Match: A0A4S2MAP1 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_001474 PE=4 SV=1)

HSP 1 Score: 180.644 bits (457), Expect = 4.056e-51
Identity = 98/254 (38.58%), Postives = 149/254 (58.66%), Query Frame = 2 
Query:  188 SILKSNTRQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSG--LNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALS-ERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINV 940
            +I     R AGHSHWQNV+ TK+++D+QK+  A +  R V NAIK G GIRDPK+N+ LA+V+  AKA +VP+STLE+ +      DPYFIE QAPGG+F+++ESC K    ER  I  +VK+YG        + + F  +    C P   G  L + D A    +++GA +V  E  +   +  +KF C+P +++ ++  L  +  ++ +  E+ L P  K++++S    N+ EM  +IR+  E V RI  NV
Sbjct:   33 AIFTEARRFAGHSHWQNVRHTKEARDKQKAKTAQLYIRAVNNAIKAGGGIRDPKLNSHLASVLAEAKANSVPLSTLERFIKAEFTTDPYFIEVQAPGGLFILIESCAKSVNAERHQIAGLVKRYGCSLSTAGKIASEFFDRLAWICVPGGPGSNLTDLDAATNFGIDIGANDV--EEVTVDGQIAFKFYCDPSNVEQMRLLLERDHSIQPMSVEDVLVPKCKVQVDSKAYANLLEMYERIRDQHEYVDRIVDNV 284
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. TrEMBL
Match: A0A183KRZ8 (Uncharacterized protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS17833 PE=4 SV=1)

HSP 1 Score: 179.489 bits (454), Expect = 7.957e-51
Identity = 106/287 (36.93%), Postives = 163/287 (56.79%), Query Frame = 2 
Query:  110 IRTVFFNKLSIKSLYKIENSLQFSFNSIL-KSNT------RQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCP-NSILNAAFKYKGEIACKPNSS-GLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSE-RKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINV 940
            ++ V F    +  +Y ++ + Q   +  + K N       R AGH+HWQNVK  K++ DR+K+  A    +    AI++G GIRDPK N+KLAAV+  AK  +VP ST +KLL  ++ I+PY IE +APGG+F++VES  KH   ER  + S+ KKYGF   P   I +  F + G +     SS  L++ D A  + +E+GA+EV  EL S  E+  Y F C   +++N++ +L     + +I +++   P   + I   ++  +DEM  KI+ + E V RIF NV
Sbjct:    4 LKFVLFAHRLLSPMYIVDRTFQIPVHLFVNKINVFSTQIKRFAGHAHWQNVKHIKEAGDREKAQTALYYIKAAQKAIRDGGGIRDPKKNSKLAAVLAEAKTKSVPFSTFDKLLSTDNQIEPYIIEIKAPGGLFVIVESRAKHVANERQRVCSIAKKYGFSLVPAGDIADKFFDHIGLVTVSAKSSKQLSDLDAATNLGIEIGAKEV--EL-SSGEDQNYHFHCEVHEIENLRQSLETIHHIPVINTQDIYSPKIFVPIHHDVRQTLDEMYDKIKTSLEYVDRIFDNV 287
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Cavefish
Match: taco1 (translational activator of cytochrome c oxidase 1 [Source:NCBI gene;Acc:103043171])

HSP 1 Score: 83.1889 bits (204), Expect = 5.422e-18
Identity = 62/223 (27.80%), Postives = 111/223 (49.78%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLL---KNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEII-----YSENYLDPINKIKIES 859
            AGH+ W  VK  K  KD  +S        L+  A+KEG     P+ N  LA +I++ ++ ++P ST++  +    K+     +  E + PGG  L++E    + T+   +I  ++ K G     + + +  F+ KG +  +    G  + + ALE+A+E GAE+V  E + E    + +FIC+    K VQ+AL +  +  +     Y  N+  P+ + ++ES
Sbjct:   44 AGHNKWSKVKDIKIPKDAARSRVIIKYMNLIRVAVKEGG--PKPEFNVALAQLIEQCRSKSIPKSTIDNAIKGGEKSKTAAQFLYEARGPGGCLLLIEVLTDNNTRTNQEIKRILMKNG--GVLSDVGHHNFERKGVVVAE---RGSISTERALELAIESGAEDV-QETEDEEANPILQFICDTSSTKTVQTALKDLGVHTLSTGIEYISNHTTPLAQAQLES 258
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Cavefish
Match: taco1 (translational activator of cytochrome c oxidase 1 [Source:NCBI gene;Acc:103043171])

HSP 1 Score: 83.1889 bits (204), Expect = 5.422e-18
Identity = 62/223 (27.80%), Postives = 111/223 (49.78%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLL---KNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEII-----YSENYLDPINKIKIES 859
            AGH+ W  VK  K  KD  +S        L+  A+KEG     P+ N  LA +I++ ++ ++P ST++  +    K+     +  E + PGG  L++E    + T+   +I  ++ K G     + + +  F+ KG +  +    G  + + ALE+A+E GAE+V  E + E    + +FIC+    K VQ+AL +  +  +     Y  N+  P+ + ++ES
Sbjct:   44 AGHNKWSKVKDIKIPKDAARSRVIIKYMNLIRVAVKEGG--PKPEFNVALAQLIEQCRSKSIPKSTIDNAIKGGEKSKTAAQFLYEARGPGGCLLLIEVLTDNNTRTNQEIKRILMKNG--GVLSDVGHHNFERKGVVVAE---RGSISTERALELAIESGAEDV-QETEDEEANPILQFICDTSSTKTVQTALKDLGVHTLSTGIEYISNHTTPLAQAQLES 258
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Sea Lamprey
Match: taco1 (translational activator of mitochondrially encoded cytochrome c oxidase I [Source:ZFIN;Acc:ZDB-GENE-070410-35])

HSP 1 Score: 92.0485 bits (227), Expect = 8.391e-22
Identity = 71/249 (28.51%), Postives = 128/249 (51.41%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDPYFI---EFQAPGGIFLVVESCNKHTTKERTDIISVVKKYG---FKSCPNSILNAAFKYKGEIACKPNSSGLN-NEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIESIMKTNVDEMIGKIRNNFETVHRIFINV 940
            AGH+ W  VK  K  KD  +S   + L  ++ +A+KEG    +P +N+ LA++++  ++ N+P +T E  +   D   P  I     + PGG  L+VE+C  +  +  +DI ++V K G   F+   NS     F+ +G +  + +S   N   +EALE+A+EVGAE+V  ++ SE +    +F+C    L+ V+  L       + S     P+  ++++S  + +V   +  +  +   V R++ NV
Sbjct:   54 AGHNKWSKVKNIKGPKDTARSLEFSKLGIMIRHAVKEGGP--NPDMNSALASLLEVCRSKNMPKATYETAIKGADKSKPLTIINFGVRGPGGFALLVETCTDNYKRTNSDIRNLVNKNGGSLFEGAKNS-----FEQRGVVTIRKDSDRKNLGLEEALELAIEVGAEDVREQI-SEDDPVNLQFVCAVQSLREVRERLMSLGFTPLSSALEFIPVRTVELKS-EEMDVAAHLVHLMESLPDVVRVYDNV 293
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Yeast
Match: YGR021W_mRNA (Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000003253])

HSP 1 Score: 70.4774 bits (171), Expect = 2.408e-14
Identity = 67/255 (26.27%), Postives = 109/255 (42.75%), Query Frame = 2 
Query:  107 MIRTVFFNKLSIKSLYKIENSLQFSFNSILKSNTRQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLK----------NDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEV-GAEEVL--------FELDSETEES--VYKFICNPMDLKNVQSALSERKMEI 808
            ++R  +  +L       ++NS  FS   +L S+ R +GH+ W  +K  K   D +++         +  ++K G+GI DP +N +LA  I+ A   NV    +E  + K          ++  +    E   PGG+ +VVE+   +  +    I S   K      P       F  KG +   P    L+ ED+ LE  LE+ G E++          E D+ETE +   Y+ +  P D   V + L ER   I
Sbjct:    2 LVRNRYLGEL-------LKNSRSFS---VLNSSVR-SGHNKWSTIKHGKAKNDAERNKINNKFANQIAMSVKLGNGITDPSMNIRLATSIELANKNNVSKKVIENAIRKASGSSASGKDSNASELCVYEGMGPGGVAIVVEALTDNKNRTIGLIRSAFNKANGSMTPTLFF---FDKKGYVTMVP-PKMLDTEDKVLESVLEIQGIEDIAPVQEDAEDLECDTETETTGQTYEAVMEPADTNKVAALLKERGFHI 241
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Nematostella
Match: EDO29315 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T3Z7])

HSP 1 Score: 60.077 bits (144), Expect = 1.342e-10
Identity = 44/168 (26.19%), Postives = 76/168 (45.24%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKN------DIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEV 700
            AGHS W N+K  K  +D ++    T + R +  A K G  I  P  N +L   +D+A   N+    +++ + +       D +     E  A GG+ ++VE+   +  +   ++     K G     +  +   F  KG+++  P  S    ED  +E ALE GA++V
Sbjct:    2 AGHSKWANIKHRKGRQDAKRGKIFTKIIRELTVAAKHGGPI--PADNPRLRLAVDKALTSNMSRDVIDRAIARGAGNNEADNVAELSYEGYALGGVAIIVEAMTDNRNRTAAEVRHAFTKCGGNLGTDGSVAYMFDRKGQLSFAPGVS----EDALMEAALEAGADDV 163
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Medaka
Match: taco1 (translational activator of cytochrome c oxidase 1 [Source:NCBI gene;Acc:101168821])

HSP 1 Score: 75.8702 bits (185), Expect = 1.999e-15
Identity = 55/205 (26.83%), Postives = 102/205 (49.76%), Query Frame = 2 
Query:  215 AGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDP---YFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLN-NEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYS 817
            AGH+ W  VK  K  KD  +         ++  A+KEG    +P +N  LA ++++ ++ N+P ++++  +   +   P   + +E + PGG  L++E    + ++   +I  ++ K G         N  F   G +       G N + ++ALE+A+E GA +V  E + E E+ + KFIC+  DL  V+ AL  +++ +  S
Sbjct:   55 AGHNKWSKVKHIKGPKDEARGRMFMKFGMMIRIAVKEGGS--NPDLNVNLAHILEQCRSKNMPKASIDAAVKSAEKAKPALQHMLEARGPGGCVLLIEVLTDNNSRTHQEIKRLLNKNGGTLSDGCRHN--FNRSGVVVL----PGHNISSEKALELAIESGAADVQ-ETEDEEEKPLLKFICDVADLNKVRVALERQELPVTSS 250
[Close]
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Planmine SMEST
Match: SMESG000039610.1 (SMESG000039610.1)

HSP 1 Score: 452.595 bits (1163), Expect = 2.139e-162
Identity = 219/221 (99.10%), Postives = 220/221 (99.55%), Query Frame = 2 
Query:  107 MIRTVFFNKLSIKSLYKIENSLQFSFNSILKSNTRQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLK 769
            MIRTVFFNKLSI SLYKIENSLQF+FNSILKSNTRQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLK
Sbjct:    1 MIRTVFFNKLSINSLYKIENSLQFTFNSILKSNTRQAGHSHWQNVKQTKDSKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPMSTLEKLLLKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKKYGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLFELDSETEESVYKFICNPMDLK 221

HSP 2 Score: 50.8322 bits (120), Expect = 3.151e-7
Identity = 23/23 (100.00%), Postives = 23/23 (100.00%), Query Frame = 1 
Query:  769 KCAICFVREENGNNLQRKLFRSN 837
            KCAICFVREENGNNLQRKLFRSN
Sbjct:  222 KCAICFVREENGNNLQRKLFRSN 244
The following BLAST results are available for this feature:
BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
TACO16.294e-1928.92translational activator of cytochrome c oxidase I ... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
taco-16.927e-1927.82Translational Activator of Cytochrome c Oxidase [... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG49572.273e-1727.49gene:FBgn0032205 transcript:FBtr0079985[more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
taco14.303e-1729.53translational activator of mitochondrially encoded... [more]
taco14.795e-1729.53translational activator of mitochondrially encoded... [more]
taco17.982e-1729.53translational activator of mitochondrially encoded... [more]
taco18.060e-1729.53translational activator of mitochondrially encoded... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
TACO12.193e-1624.09translational activator of mitochondrially encoded... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Taco11.954e-1727.71translational activator of mitochondrially encoded... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8RAR7|Y1135_CALS45.232e-2027.31Probable transcriptional regulatory protein TTE113... [more]
sp|B8CXG6|Y1235_HALOH1.303e-1927.27Probable transcriptional regulatory protein Hore_1... [more]
sp|C5CGU7|Y1935_KOSOT4.077e-1927.31Probable transcriptional regulatory protein Kole_1... [more]
sp|A1W753|Y1898_ACISJ1.306e-1825.98Probable transcriptional regulatory protein Ajs_18... [more]
sp|Q3A233|Y2335_PELCD1.699e-1827.31Probable transcriptional regulatory protein Pcar_2... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S8WMH12.038e-5340.89DNA-binding regulatory protein, YebC/PmpR family O... [more]
A0A075AHL24.141e-5340.89Uncharacterized protein OS=Opisthorchis viverrini ... [more]
H2KRE62.832e-5238.58Putative transcriptional regulatory protein OS=Clo... [more]
A0A4S2MAP14.056e-5138.58Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A183KRZ87.957e-5136.93Uncharacterized protein OS=Schistosoma curassoni O... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
taco15.422e-1827.80translational activator of cytochrome c oxidase 1 ... [more]
taco15.422e-1827.80translational activator of cytochrome c oxidase 1 ... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
taco18.391e-2228.51translational activator of mitochondrially encoded... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
YGR021W_mRNA2.408e-1426.27Putative protein of unknown function; the authenti... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO293151.342e-1026.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
taco11.999e-1526.83translational activator of cytochrome c oxidase 1 ... [more]
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BLAST of DNA-binding regulatory protein, YebC/PmpR family vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000039610.12.139e-16299.10SMESG000039610.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007862 ID=SMED30007862|Name=DNA-binding regulatory protein, YebC/PmpR family|organism=Schmidtea mediterranea sexual|type=transcript|length=962bp
GAAGTTTTCTGATAGCACTTTTAACTACTAATATTTTTAATATAATATAT
TTATATTATTATATATCTATTCAACTATTTATACTGTTATTCTGAACAAA
ATTTACATGATTAGGACAGTTTTTTTTAATAAGCTATCTATTAAATCTTT
ATATAAAATTGAAAATTCCTTACAATTTTCGTTCAATTCCATTTTAAAGA
GTAATACTAGACAAGCAGGTCATTCACATTGGCAAAATGTTAAACAAACT
AAGGATTCAAAGGATCGACAGAAATCTTCAAATGCCACTATACTTACTCG
ATTAGTATTAAATGCGATTAAAGAAGGTGATGGGATTAGAGATCCTAAAA
TAAACACAAAGTTAGCTGCCGTGATTGATAGAGCTAAAGCTCTTAATGTG
CCAATGTCAACCTTGGAAAAACTTTTATTGAAAAATGACATTATTGATCC
TTATTTCATTGAATTCCAAGCTCCTGGTGGTATTTTTTTAGTTGTGGAAT
CATGCAATAAACATACGACTAAAGAAAGAACGGATATTATTTCCGTTGTT
AAAAAATATGGATTTAAATCTTGCCCCAACAGTATTTTAAACGCCGCCTT
CAAATATAAAGGGGAAATAGCATGTAAACCAAATTCAAGTGGCCTGAATA
ACGAAGATGAAGCTCTGGAAATGGCACTGGAAGTGGGAGCAGAGGAAGTA
CTATTTGAACTAGATTCAGAAACTGAAGAATCGGTTTATAAATTTATCTG
TAATCCGATGGATCTTAAAAATGTGCAATCTGCTTTGTCAGAGAGGAAAA
TGGAAATAATTTACAGCGAAAATTATTTAGATCCAATTAATAAAATTAAA
ATTGAGAGCATAATGAAAACTAATGTCGATGAGATGATAGGGAAAATAAG
GAATAATTTTGAAACGGTCCACAGAATATTTATTAATGTTGAATAAATTG
TGGTTGCTCTTT
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protein sequence of SMED30007862-orf-1

>SMED30007862-orf-1 ID=SMED30007862-orf-1|Name=SMED30007862-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=280bp
MIRTVFFNKLSIKSLYKIENSLQFSFNSILKSNTRQAGHSHWQNVKQTKD
SKDRQKSSNATILTRLVLNAIKEGDGIRDPKINTKLAAVIDRAKALNVPM
STLEKLLLKNDIIDPYFIEFQAPGGIFLVVESCNKHTTKERTDIISVVKK
YGFKSCPNSILNAAFKYKGEIACKPNSSGLNNEDEALEMALEVGAEEVLF
ELDSETEESVYKFICNPMDLKNVQSALSERKMEIIYSENYLDPINKIKIE
SIMKTNVDEMIGKIRNNFETVHRIFINVE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0003674molecular_function
Vocabulary: INTERPRO
TermDefinition
IPR002876Transcrip_reg_TACO1-like
IPR026564Transcrip_reg_TACO1-like_dom3
IPR017856Integrase_Zn-bd_dom-like_N
IPR029072YebC-like
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005739mitochondrion
Vocabulary: biological process
TermDefinition
GO:0006417regulation of translation
GO:0008150biological_process