Cyclic nucleotide gated channel 1

Overview
NameCyclic nucleotide gated channel 1
Smed IDSMED30007846
Length (bp)2784
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cyclic nucleotide gated channel 1 (SMED30007846) t-SNE clustered cells

Violin plots show distribution of expression levels for Cyclic nucleotide gated channel 1 (SMED30007846) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cyclic nucleotide gated channel 1 (SMED30007846) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cyclic nucleotide gated channel 1 (SMED30007846) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30007846

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30007846h1SMcG0005006 SmedASXL_016633SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30007846h1SMcG0005006 Contig36128uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30007846h1SMcG0005006 Contig36128newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30007846h1SMcG0005006 dd_Smed_v4_16523_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30007846h1SMcG0005006 dd_Smed_v4_16523_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30007846h1SMcG0005006 dd_Smed_v4_16523_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30007846h1SMcG0005006 dd_Smed_v6_16523_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
oocyteSMED30007846h1SMcG0005006 Contig43340newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
oocyteSMED30007846h1SMcG0005006 Contig43340uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
vitelline glandSMED30007846h1SMcG0005006 Contig43340newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
vitelline glandSMED30007846h1SMcG0005006 Contig43340uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30007846h1SMcG0005006 Contig43340newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30007846h1SMcG0005006 Contig43340uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Match: HCN1 (hyperpolarization activated cyclic nucleotide gated potassium channel 1 [Source:HGNC Symbol;Acc:HGNC:4845])

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 286/534 (53.56%), Postives = 394/534 (73.78%), Query Frame = 3
Query:  675 KDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLD 2264
            +D++  +    +++ QF S  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML+M++ NL+I+PV ++FFT+     W+IFN  SDTVFL D+ +NFRTG +  D S EIIL+PK+I  NYL+SWF +D ISSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV   ++ +  W +QY+++LFKAMSHML IGYG   P S+S+ WIT++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQ+I +YYEHRYQGK+F+E+ IL ELN+ LRE+++N+NCR LVA +P F  AD +FV+ ++SKL +EVFQPGD II+EG +G KMYFIQ G+  +ITK  + +  L+DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+  +  F+ DL+
Sbjct:   82 EDAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNED-SSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQK--FQKDLN 610          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Match: HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 [Source:HGNC Symbol;Acc:HGNC:4846])

HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0
Identity = 280/515 (54.37%), Postives = 382/515 (74.17%), Query Frame = 3
Query:  681 SQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIG 2213
             + + S +S+++ QF +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI++ D + EIIL+P+ I + YLR+WF +D +SSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + IC L+ +MLLL HW+ C+QFL+P+L +FP   WV    + +  W E Y+++LFKAMSHML IGYGR  P S+++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQ+I +YYEHRYQGKMF+ED IL ELN  LRE+++N+NCR LVA++P F  AD +FV+ +++KL +EVFQPGD II+EGTIG KMYFIQ G+V ++TK G     LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG
Sbjct:  153 GEPRGSQASFMQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIG 664          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Match: HCN1 (hyperpolarization activated cyclic nucleotide gated potassium channel 1 [Source:HGNC Symbol;Acc:HGNC:4845])

HSP 1 Score: 571.237 bits (1471), Expect = 0.000e+0
Identity = 283/525 (53.90%), Postives = 388/525 (73.90%), Query Frame = 3
Query:  675 KDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITN 2237
            +D++  +    +++ QF S  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML+M++ NL+I+PV ++FFT+     W+IFN  SDTVFL D+ +NFRTG +  D S EIIL+PK+I  NYL+SWF +D ISSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV   ++ +  W +QY+++LFKAMSHML IGYG   P S+S+ WIT++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQ+I +YYEHRYQGK+F+E+ IL ELN+ LRE+++N+NCR LVA +P F  AD +FV+ ++SKL +EVFQPGD II+EG +G KMYFIQ G+  +ITK  + +  L+DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +I    D  T+
Sbjct:   82 EDAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNEDSS-EIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIAKQTDFPTD 603          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Match: HCN4 (hyperpolarization activated cyclic nucleotide gated potassium channel 4 [Source:HGNC Symbol;Acc:HGNC:16882])

HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0
Identity = 279/517 (53.97%), Postives = 384/517 (74.27%), Query Frame = 3
Query:  675 KDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIG 2213
             +++ +   + +++ QF +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML++++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI++ D + EIIL+P+ I   YL+SWF +D ISSIP+DYIFL V    +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV    + ++ W +QY+++LFKAMSHML IGYGR  P  +S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQRI +YYEHRYQGKMF+E+ IL EL+E LRE++IN+NCR LVA++P F  AD +FV+ +++KL +EVFQPGD II+EGTIG KMYFIQ G+V ++TK G   T L+DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG
Sbjct:  202 PEAEVRLGQAGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVEDNT-EIILDPQRIKMKYLKSWFMVDFISSIPVDYIFLIVETRIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSINNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIG 715          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Match: HCN3 (hyperpolarization activated cyclic nucleotide gated potassium channel 3 [Source:HGNC Symbol;Acc:HGNC:19183])

HSP 1 Score: 550.821 bits (1418), Expect = 0.000e+0
Identity = 270/515 (52.43%), Postives = 371/515 (72.04%), Query Frame = 3
Query:  714 KEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVY-AGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNRE 2243
            +    +  QP+ NK +L++FGS  AV  E++R +    WIIHP S FRFYWDL ML++++ NLI+LPV ++FF +     W++FN  SDT FL D+ +NFRTGI++ ++  EI+L P+ I   YLR+WF +DLISSIP+DYIFL V         VY   + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV    + +  W  QY+ +LFKAMSHML IGYG+  P  + + W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQRI  YYEHRYQGKMF+E+ IL EL+E LRE++IN+ CR LVA +P F +AD SFV+ V++KL +EVFQPGDL+++EG++G KMYFIQ G++ ++ + G   T L+DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F AVLE +P+MRR  E+VA +RL +IG    I+  + 
Sbjct:   46 RRHLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVV-EEGAEILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLAR-GARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLLRIGKKNSILQRKR 558          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Match: unc-103 (Potassium voltage-gated channel unc-103 [Source:UniProtKB/Swiss-Prot;Acc:G5EFJ9])

HSP 1 Score: 160.999 bits (406), Expect = 1.956e-40
Identity = 144/544 (26.47%), Postives = 248/544 (45.59%), Query Frame = 3
Query:  657 DLNTDEKDSQQKQS--TSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPC-----SSFRFYWDLFMLVMLIANLIILPVIVSF-------------FTDSMRIQWVIFNCFSDTVFLADIAVNFRTGIL-LTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLML---LLGHWNACIQFLI-PVLMEFPTESWVVKCKLQHSYWF---------------EQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQ-GKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTN--AKRCATVRAEVYCSLYSLDSEQFKAVLENYP 2159
            D N D++    KQS  +S ++ E  L+    SD++   K+      V+ E K Q       IH C     S F+  WD  +L+++I   +  P + +F             FT+ + I  +I     D +F+ DI +NFRT  +   D++ +++ +P  IA +Y + WF +D+++++P D + ++ N  E                L  LL   RLLRL R+ R + ++ E+        G   L+LLM    L+ HW ACI + I    +     +W+ +   Q +  +                +Y  SL+  +S + SIG+G    T+ SE   TII M+ G+  YA   G+ +A+IQ   +    Y  +  ++ E++ + ++P  LRQR+  Y++H +      + + +L    +CL+  +  +  R L++    F  +    +  +  +       PGD ++  G I T +YFI  G V+I+  D  V+  L     FGE  LL +   K    VRA  YC L+ +  +    VL+ YP
Sbjct:   28 DKNDDKQRFLPKQSRGSSRFVSEDVLNN---SDDEEENKVLSLGADVLPEYKLQPTR----IHHCTIVHYSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEIVDLIV----DIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFDLLLVSTNSDET-------------TTLIGLLKTARLLRLVRVARKLDRYSEY--------GAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEYTWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGSTPGCLRALSMRFRTTHSPPGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 539          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Match: unc-103 (Potassium voltage-gated channel unc-103 [Source:UniProtKB/Swiss-Prot;Acc:G5EFJ9])

HSP 1 Score: 158.688 bits (400), Expect = 1.250e-39
Identity = 142/558 (25.45%), Postives = 254/558 (45.52%), Query Frame = 3
Query:  615 TQKRLSDTTGANNLDLNTDEKDSQQKQSTS--SYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPC-----SSFRFYWDLFMLVMLIANLIILPVIVSF-------------FTDSMRIQWVIFNCFSDTVFLADIAVNFRTGIL-LTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLML---LLGHWNACIQFLI-PVLMEFPTESWVVKCKLQHSYWF---------------EQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQ-GKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTN--AKRCATVRAEVYCSLYSLDSEQFKAVLENYP 2159
            +Q+ L   +G+N+ + N   K++ +K+  +  +++   F+        + A K+      V+ E K Q       IH C     S F+  WD  +L+++I   +  P + +F             FT+ + I  +I     D +F+ DI +NFRT  +   D++ +++ +P  IA +Y + WF +D+++++P D + ++ N  E                L  LL   RLLRL R+ R + ++ E+        G   L+LLM    L+ HW ACI + I    +     +W+ +   Q +  +                +Y  SL+  +S + SIG+G    T+ SE   TII M+ G+  YA   G+ +A+IQ   +    Y  +  ++ E++ + ++P  LRQR+  Y++H +      + + +L    +CL+  +  +  R L++    F  +    +  +  +       PGD ++  G I T +YFI  G V+I+  D  V+  L     FGE  LL +   K    VRA  YC L+ +  +    VL+ YP
Sbjct:   73 SQRPLVARSGSNSSEHNLQIKEAVKKKPVADIAHVSGTFVCVCV----RGAQKVLSLGADVLPEYKLQPTR----IHHCTIVHYSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEIVDLIV----DIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFDLLLVSTNSDET-------------TTLIGLLKTARLLRLVRVARKLDRYSEY--------GAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEYTWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGSTPGCLRALSMRFRTTHSPPGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 597          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Match: unc-103 (Potassium voltage-gated channel unc-103 [Source:UniProtKB/Swiss-Prot;Acc:G5EFJ9])

HSP 1 Score: 158.688 bits (400), Expect = 1.385e-39
Identity = 135/512 (26.37%), Postives = 232/512 (45.31%), Query Frame = 3
Query:  747 DNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPC-----SSFRFYWDLFMLVMLIANLIILPVIVSF-------------FTDSMRIQWVIFNCFSDTVFLADIAVNFRTGIL-LTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLML---LLGHWNACIQFLI-PVLMEFPTESWVVKCKLQHSYWF---------------EQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQ-GKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTN--AKRCATVRAEVYCSLYSLDSEQFKAVLENYP 2159
            +N  AL +      V+ E K Q       IH C     S F+  WD  +L+++I   +  P + +F             FT+ + I  +I     D +F+ DI +NFRT  +   D++ +++ +P  IA +Y + WF +D+++++P D + ++ N  E                L  LL   RLLRL R+ R + ++ E+        G   L+LLM    L+ HW ACI + I    +     +W+ +   Q +  +                +Y  SL+  +S + SIG+G    T+ SE   TII M+ G+  YA   G+ +A+IQ   +    Y  +  ++ E++ + ++P  LRQR+  Y++H +      + + +L    +CL+  +  +  R L++    F  +    +  +  +       PGD ++  G I T +YFI  G V+I+  D  V+  L     FGE  LL +   K    VRA  YC L+ +  +    VL+ YP
Sbjct:   81 NNVSALGVLSLGADVLPEYKLQPTR----IHHCTIVHYSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEIVDLIV----DIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFDLLLVSTNSDET-------------TTLIGLLKTARLLRLVRVARKLDRYSEY--------GAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEYTWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGSTPGCLRALSMRFRTTHSPPGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 563          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Match: unc-103 (Potassium voltage-gated channel unc-103 [Source:UniProtKB/Swiss-Prot;Acc:G5EFJ9])

HSP 1 Score: 158.303 bits (399), Expect = 1.807e-39
Identity = 134/508 (26.38%), Postives = 230/508 (45.28%), Query Frame = 3
Query:  759 ALKLFGSKNAVIQEKKRQQKEAKWIIHPC-----SSFRFYWDLFMLVMLIANLIILPVIVSF-------------FTDSMRIQWVIFNCFSDTVFLADIAVNFRTGIL-LTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLML---LLGHWNACIQFLI-PVLMEFPTESWVVKCKLQHSYWF---------------EQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQ-GKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTN--AKRCATVRAEVYCSLYSLDSEQFKAVLENYP 2159
            AL +      V+ E K Q       IH C     S F+  WD  +L+++I   +  P + +F             FT+ + I  +I     D +F+ DI +NFRT  +   D++ +++ +P  IA +Y + WF +D+++++P D + ++ N  E                L  LL   RLLRL R+ R + ++ E+        G   L+LLM    L+ HW ACI + I    +     +W+ +   Q +  +                +Y  SL+  +S + SIG+G    T+ SE   TII M+ G+  YA   G+ +A+IQ   +    Y  +  ++ E++ + ++P  LRQR+  Y++H +      + + +L    +CL+  +  +  R L++    F  +    +  +  +       PGD ++  G I T +YFI  G V+I+  D  V+  L     FGE  LL +   K    VRA  YC L+ +  +    VL+ YP
Sbjct:   77 ALAVLSLGADVLPEYKLQPTR----IHHCTIVHYSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEIVDLIV----DIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFDLLLVSTNSDET-------------TTLIGLLKTARLLRLVRVARKLDRYSEY--------GAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEYTWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGSTPGCLRALSMRFRTTHSPPGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 555          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Match: unc-103 (Potassium voltage-gated channel unc-103 [Source:UniProtKB/Swiss-Prot;Acc:G5EFJ9])

HSP 1 Score: 156.377 bits (394), Expect = 4.252e-39
Identity = 132/498 (26.51%), Postives = 227/498 (45.58%), Query Frame = 3
Query:  789 VIQEKKRQQKEAKWIIHPC-----SSFRFYWDLFMLVMLIANLIILPVIVSF-------------FTDSMRIQWVIFNCFSDTVFLADIAVNFRTGIL-LTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLML---LLGHWNACIQFLI-PVLMEFPTESWVVKCKLQHSYWF---------------EQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQ-GKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTN--AKRCATVRAEVYCSLYSLDSEQFKAVLENYP 2159
            V+ E K Q       IH C     S F+  WD  +L+++I   +  P + +F             FT+ + I  +I     D +F+ DI +NFRT  +   D++ +++ +P  IA +Y + WF +D+++++P D + ++ N  E                L  LL   RLLRL R+ R + ++ E+        G   L+LLM    L+ HW ACI + I    +     +W+ +   Q +  +                +Y  SL+  +S + SIG+G    T+ SE   TII M+ G+  YA   G+ +A+IQ   +    Y  +  ++ E++ + ++P  LRQR+  Y++H +      + + +L    +CL+  +  +  R L++    F  +    +  +  +       PGD ++  G I T +YFI  G V+I+  D  V+  L     FGE  LL +   K    VRA  YC L+ +  +    VL+ YP
Sbjct:   11 VLPEYKLQPTR----IHHCTIVHYSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEIVDLIV----DIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFDLLLVSTNSDET-------------TTLIGLLKTARLLRLVRVARKLDRYSEY--------GAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEYTWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGSTPGCLRALSMRFRTTHSPPGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 479          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Match: Ih (gene:FBgn0263397 transcript:FBtr0100369)

HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0
Identity = 344/519 (66.28%), Postives = 436/519 (84.01%), Query Frame = 3
Query:  699 TSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRG-ENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEE--FLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNRED 2246
            ++++LK Q  S+FQP+DN+LA+KLFGS+ A+++E+ RQ+    W+IHPCSSFRFYWDL ML++L+ANLIILPV +SFF D +  +W+ FNC SDT+FL DI VNFRTGI+  D ++++IL+PK+IA++YLR+WFFLDLISSIPLDYIFL  N+   +    ++AG+ LRILRLAKLLS++RLLRLSRLVRYVSQWEE  FLN+AS F+ I  L+ +MLL+GHW+ C+QFL+P+L  FP+ SWV   +LQ SYW EQY+W+LFKAMSHML IGYGRFPP S+++ W+T++SM++GATCYALF+GHA  LIQS D+S+R YREK KQVEEYM YRKLPR +RQRI  Y+EHRYQGK F+E+ IL EL+E LRE VINYNCR+LVA+VPFF  AD +FVS+VV+KL YEVFQPGD+IIKEGTIGTKMYFIQEG+VDI+  +GEV TSLSDGSYFGEICLLTNA+R A+VRAE YC+L+SL  + F  VL+ YPLMR+TME+VAAERL+KIG NP+I+  +++
Sbjct:  701 SANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDE 1219          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Match: Ih (gene:FBgn0263397 transcript:FBtr0290109)

HSP 1 Score: 719.153 bits (1855), Expect = 0.000e+0
Identity = 345/524 (65.84%), Postives = 436/524 (83.21%), Query Frame = 3
Query:  699 TSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHF------VYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEE--FLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNRED 2246
            ++++LK Q  S+FQP+DN+LA+KLFGS+ A+++E+ RQ+    W+IHPCSSFRFYWDL ML++L+ANLIILPV +SFF D +  +W+ FNC SDT+FL DI VNFRTGI+  D ++++IL+PK+IA++YLR+WFFLDLISSIPLDYIFL  N+      F      ++AG+ LRILRLAKLLS++RLLRLSRLVRYVSQWEE  FLN+AS F+ I  L+ +MLL+GHW+ C+QFL+P+L  FP+ SWV   +LQ SYW EQY+W+LFKAMSHML IGYGRFPP S+++ W+T++SM++GATCYALF+GHA  LIQS D+S+R YREK KQVEEYM YRKLPR +RQRI  Y+EHRYQGK F+E+ IL EL+E LRE VINYNCR+LVA+VPFF  AD +FVS+VV+KL YEVFQPGD+IIKEGTIGTKMYFIQEG+VDI+  +GEV TSLSDGSYFGEICLLTNA+R A+VRAE YC+L+SL  + F  VL+ YPLMR+TME+VAAERL+KIG NP+I+  +++
Sbjct:  701 SANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDE 1224          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Match: Ih (gene:FBgn0263397 transcript:FBtr0308835)

HSP 1 Score: 709.138 bits (1829), Expect = 0.000e+0
Identity = 344/522 (65.90%), Postives = 438/522 (83.91%), Query Frame = 3
Query:  690 KQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRG-ENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEE--FLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNRED 2246
            ++ ++++LK Q  S+FQP+DN+LA+KLFGS+ A+++E+ RQ+    W+IHPCSSFRFYWDL ML++L+ANLIILPV +SFF D +  +W+ FNC SDT+FL DI VNFRTGI+  D ++++IL+PK+IA++YLR+WFFLDLISSIPLDYIFL  N+   +    ++AG+ LRILRLAKLLS++RLLRLSRLVRYVSQWEE  FLN+AS F+ I  L+ +MLL+GHW+ C+QFL+P+L  FP+ SWV   +LQ SYW EQY+W+LFKAMSHML IGYGRFPP S+++ W+T++SM++GATCYALF+GHA  LIQS D+S+R YREK KQVEEYM YRKLPR +RQRI  Y+EHRYQGK F+E+ IL EL+E LRE VINYNCR+LVA+VPFF  AD +FVS+VV+KL YEVFQPGD+IIKEGTIGTKMYFIQEG+VDI+  +GEV TSLSDGSYFGEICLLTNA+R A+VRAE YC+L+SL  + F  VL+ YPLMR+TME+VAAERL+KIG NP+I+  +++
Sbjct:   26 EKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDE 547          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Match: Ih (gene:FBgn0263397 transcript:FBtr0290292)

HSP 1 Score: 709.138 bits (1829), Expect = 0.000e+0
Identity = 344/522 (65.90%), Postives = 438/522 (83.91%), Query Frame = 3
Query:  690 KQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRG-ENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEE--FLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNRED 2246
            ++ ++++LK Q  S+FQP+DN+LA+KLFGS+ A+++E+ RQ+    W+IHPCSSFRFYWDL ML++L+ANLIILPV +SFF D +  +W+ FNC SDT+FL DI VNFRTGI+  D ++++IL+PK+IA++YLR+WFFLDLISSIPLDYIFL  N+   +    ++AG+ LRILRLAKLLS++RLLRLSRLVRYVSQWEE  FLN+AS F+ I  L+ +MLL+GHW+ C+QFL+P+L  FP+ SWV   +LQ SYW EQY+W+LFKAMSHML IGYGRFPP S+++ W+T++SM++GATCYALF+GHA  LIQS D+S+R YREK KQVEEYM YRKLPR +RQRI  Y+EHRYQGK F+E+ IL EL+E LRE VINYNCR+LVA+VPFF  AD +FVS+VV+KL YEVFQPGD+IIKEGTIGTKMYFIQEG+VDI+  +GEV TSLSDGSYFGEICLLTNA+R A+VRAE YC+L+SL  + F  VL+ YPLMR+TME+VAAERL+KIG NP+I+  +++
Sbjct:    9 EKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDE 530          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Match: Ih (gene:FBgn0263397 transcript:FBtr0308836)

HSP 1 Score: 709.138 bits (1829), Expect = 0.000e+0
Identity = 344/522 (65.90%), Postives = 438/522 (83.91%), Query Frame = 3
Query:  690 KQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRG-ENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEE--FLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNRED 2246
            ++ ++++LK Q  S+FQP+DN+LA+KLFGS+ A+++E+ RQ+    W+IHPCSSFRFYWDL ML++L+ANLIILPV +SFF D +  +W+ FNC SDT+FL DI VNFRTGI+  D ++++IL+PK+IA++YLR+WFFLDLISSIPLDYIFL  N+   +    ++AG+ LRILRLAKLLS++RLLRLSRLVRYVSQWEE  FLN+AS F+ I  L+ +MLL+GHW+ C+QFL+P+L  FP+ SWV   +LQ SYW EQY+W+LFKAMSHML IGYGRFPP S+++ W+T++SM++GATCYALF+GHA  LIQS D+S+R YREK KQVEEYM YRKLPR +RQRI  Y+EHRYQGK F+E+ IL EL+E LRE VINYNCR+LVA+VPFF  AD +FVS+VV+KL YEVFQPGD+IIKEGTIGTKMYFIQEG+VDI+  +GEV TSLSDGSYFGEICLLTNA+R A+VRAE YC+L+SL  + F  VL+ YPLMR+TME+VAAERL+KIG NP+I+  +++
Sbjct:   26 EKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDE 547          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Match: hcn4 (hyperpolarization activated cyclic nucleotide-gated potassium channel 4 [Source:ZFIN;Acc:ZDB-GENE-050420-360])

HSP 1 Score: 586.645 bits (1511), Expect = 0.000e+0
Identity = 286/517 (55.32%), Postives = 384/517 (74.27%), Query Frame = 3
Query:  702 SSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
            + ++  QF +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML++++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI+  D + EIIL+P+ I   YLRSWF +D ISSIP+DYIFL V    +   F    + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV K K+ +  W +QY+++LFKAMSHML IGYG +PP  +++ W+TI+SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQRI +YYEHRYQGKMF+E+ IL ELNE LRE++IN+NCR LVA++P F  AD +FV+ +++KL +EVFQPGD II+EGTIG KMYFIQ G+V ++TK G   T LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++
Sbjct:  172 AGFMHRQFGAMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDEHTPPWIVFNVVSDTFFLMDLVLNFRTGIVKEDNA-EIILDPQQIKIKYLRSWFVVDFISSIPVDYIFLIVETRID-SDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPADCWVAKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILQHK 685          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Match: hcn2b (hyperpolarization activated cyclic nucleotide-gated potassium channel 2b [Source:ZFIN;Acc:ZDB-GENE-030131-8228])

HSP 1 Score: 578.556 bits (1490), Expect = 0.000e+0
Identity = 287/549 (52.28%), Postives = 396/549 (72.13%), Query Frame = 3
Query:  687 QKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIG-------------CNPDIITNREDFKDDLDMVKEIV 2282
            + +   +Y++ QF +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF +     W+IFN  SDT FL D+ +NFRTGI+  D + EIIL+P+ I + YL++WF +D +SSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP++ WV   K+ +  W E Y+++LFKAMSHML IGYGR  P S+S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQ+I +YYEHRYQGKMF+E+ IL ELNE LRE+++N+NCR LVA++P F  AD +FV+ +++KL +EVFQPGD II+EGTIG KMYFIQ G+V ++TK G +   LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG              N  +  NRE+     +M++EIV
Sbjct:   74 EARDNQTYMQRQFSAMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKEETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYEDNT-EIILDPEKIKKKYLKTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHKVQHDLNSGVFNNREN-----EMIQEIV 614          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Match: hcn4l (hyperpolarization activated cyclic nucleotide-gated potassium channel 4l [Source:ZFIN;Acc:ZDB-GENE-110411-3])

HSP 1 Score: 576.63 bits (1485), Expect = 0.000e+0
Identity = 281/505 (55.64%), Postives = 376/505 (74.46%), Query Frame = 3
Query:  711 LKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIG 2213
            LK    +F  P  NK +L++FGS+ AV  E++R +    WIIHP S FRFYWDL ML++++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI+  D S EIIL+P+ I   YLRSWF +D +SSIP+DYIFL V    +   F    + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP++ WV K K+ +  W +QY+++LFKAMSHML IGYG +PP  +++ W+TI+SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQRI +YYEHRYQGKMF+E+ IL ELNE LRE++I++NCR LVA +P F  AD +FV+ +++KL +EVFQPGD II+EGT+G KMYFIQ G++ ++TK G   T +SDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG
Sbjct:   18 LKRHLFTFLLPGVNKFSLRMFGSEKAVEHEQERVKSAGFWIIHPYSDFRFYWDLIMLLLMVGNLIIIPVGITFFKDEHTPAWIVFNVVSDTFFLVDLVLNFRTGIVKED-STEIILDPQQIKVRYLRSWFAVDFLSSIPVDYIFLIVETRID-SDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVAKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIISFNCRKLVATMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTVGKKMYFIQHGVLTVLTK-GSKETKISDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFETVALDRLDRIG 519          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Match: hcn1 (hyperpolarization activated cyclic nucleotide-gated potassium channel 1 [Source:ZFIN;Acc:ZDB-GENE-110520-1])

HSP 1 Score: 575.859 bits (1483), Expect = 0.000e+0
Identity = 284/537 (52.89%), Postives = 396/537 (73.74%), Query Frame = 3
Query:  669 DEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVY-AGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLD 2264
            D+ D+  +Q    +++ QF +  QP  NK +L++FGS+ AV +E++R Q    WIIHP S FRFYWDL ML+M++ NLII+PV ++FF++     W++FN  SDT+FL D+ +NFRTGI+  ++S EIIL+PK+I  NYL+SWF +D +SSIP+DYIFL V +G  +   VY   + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV    + +  W +QY+++LFKAMSHML IGYG   P S+S+ WIT++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQ+I +YYEHRYQGK+F+ED IL ELN+ L+E+++N+NCR LVA +P F  AD +FV+ ++SKL +EVFQP D II+EGT+G KMYFIQ G+  +ITK  + +  L+DGSYFGEICLLT  +R A+VRA+ YC L+SL  + F  VLE YP+MRR  E+VA +RL +IG    ++  +  F+ DL+
Sbjct:   59 DDIDAASRQY--GFMQRQFGAMMQPGVNKFSLRMFGSQKAVEKEQERVQTAGYWIIHPYSDFRFYWDLIMLIMMMGNLIIIPVGITFFSEQTTTSWLVFNVASDTIFLVDLVMNFRTGIV-NEESSEIILDPKVIKMNYLKSWFVVDFLSSIPVDYIFLIVEKG--FDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNGMVNDSWGKQYSYALFKAMSHMLCIGYGARAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEDSILNELNDPLKEEIVNFNCRKLVATMPLFANADPNFVTGMLSKLKFEVFQPNDYIIREGTVGKKMYFIQHGVASVITKFNKEL-KLTDGSYFGEICLLTKGRRTASVRADTYCRLFSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSLLLQK--FQKDLN 587          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Match: hcn4 (hyperpolarization activated cyclic nucleotide-gated potassium channel 4 [Source:ZFIN;Acc:ZDB-GENE-050420-360])

HSP 1 Score: 572.392 bits (1474), Expect = 0.000e+0
Identity = 282/522 (54.02%), Postives = 381/522 (72.99%), Query Frame = 3
Query:  702 SSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL---------NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
            + ++  QF +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML++++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI+  D + EIIL+P+ I   YLRSWF +D ISSIP+DYIFL V    +   F    + LRI+R  K+LS+LRLLRLSRL+RY+      +         ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV K K+ +  W +QY+++LFKAMSHML IGYG +PP  +++ W+TI+SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQRI +YYEHRYQGKMF+E+ IL ELNE LRE++IN+NCR LVA++P F  AD +FV+ +++KL +EVFQPGD II+EGTIG KMYFIQ G+V ++TK G   T LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++
Sbjct:  152 AGFMHRQFGAMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDEHTPPWIVFNVVSDTFFLMDLVLNFRTGIVKEDNA-EIILDPQQIKIKYLRSWFVVDFISSIPVDYIFLIVETRID-SDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHHTHTTILHLIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPADCWVAKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILQHK 670          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Match: lsamp (limbic system associated membrane protein [Source:Xenbase;Acc:XB-GENE-5759171])

HSP 1 Score: 580.096 bits (1494), Expect = 0.000e+0
Identity = 284/528 (53.79%), Postives = 389/528 (73.67%), Query Frame = 3
Query:  669 DEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
            ++ D  + ++ S +++ Q  +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI++ D + EIIL+P+ I R YLR+WF +D +SSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FPT  WV   K+ +  W E Y+++LFKAMSHML IGYGR  P S+S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQR+ +YYEHRYQGKMF+ED IL ELNE LRE+++N+NCR LVA++P F  AD SFV+ +++KL +EVFQP D II+EGTIG KMYFIQ G+V ++TK  + V  LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++
Sbjct:  114 EDGDGGEDETRSGFMQRQLSAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTTPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPQKIKRKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIFNLIAMMLLLCHWDGCLQFLVPMLQDFPTNCWVSINKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQRLHDYYEHRYQGKMFDEDSILGELNEPLREEIVNFNCRKLVASMPLFANADPSFVTAMLTKLKFEVFQPTDYIIREGTIGKKMYFIQHGVVSVLTKGNKEV-KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHK 638          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Match: lsamp (limbic system associated membrane protein [Source:Xenbase;Acc:XB-GENE-5759171])

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 284/528 (53.79%), Postives = 389/528 (73.67%), Query Frame = 3
Query:  669 DEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
            ++ D  + ++ S +++ Q  +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI++ D + EIIL+P+ I R YLR+WF +D +SSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FPT  WV   K+ +  W E Y+++LFKAMSHML IGYGR  P S+S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQR+ +YYEHRYQGKMF+ED IL ELNE LRE+++N+NCR LVA++P F  AD SFV+ +++KL +EVFQP D II+EGTIG KMYFIQ G+V ++TK  + V  LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++
Sbjct:   86 EDGDGGEDETRSGFMQRQLSAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTTPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPQKIKRKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIFNLIAMMLLLCHWDGCLQFLVPMLQDFPTNCWVSINKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQRLHDYYEHRYQGKMFDEDSILGELNEPLREEIVNFNCRKLVASMPLFANADPSFVTAMLTKLKFEVFQPTDYIIREGTIGKKMYFIQHGVVSVLTKGNKEV-KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHK 610          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Match: lsamp (limbic system associated membrane protein [Source:Xenbase;Acc:XB-GENE-5759171])

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 284/528 (53.79%), Postives = 388/528 (73.48%), Query Frame = 3
Query:  669 DEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
            ++ D  + ++ S +++ Q  +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI++ D + EIIL+P+ I R YLR+WF +D +SSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FPT  WV   K+ +  W E Y+++LFKAMSHML IGYGR  P S+S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQR+ +YYEHRYQGKMF+ED IL ELNE LRE+++N+NCR LVA++P F  AD SFV+ +++KL +EVFQP D II+EGTIG KMYFIQ G+V ++TK G     LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++
Sbjct:   89 EDGDGGEDETRSGFMQRQLSAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTTPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPQKIKRKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIFNLIAMMLLLCHWDGCLQFLVPMLQDFPTNCWVSINKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQRLHDYYEHRYQGKMFDEDSILGELNEPLREEIVNFNCRKLVASMPLFANADPSFVTAMLTKLKFEVFQPTDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEVKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHK 613          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Match: lsamp (limbic system associated membrane protein [Source:Xenbase;Acc:XB-GENE-5759171])

HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0
Identity = 283/522 (54.21%), Postives = 386/522 (73.95%), Query Frame = 3
Query:  687 QKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
            + ++ S +++ Q  +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI++ D + EIIL+P+ I R YLR+WF +D +SSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FPT  WV   K+ +  W E Y+++LFKAMSHML IGYGR  P S+S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQR+ +YYEHRYQGKMF+ED IL ELNE LRE+++N+NCR LVA++P F  AD SFV+ +++KL +EVFQP D II+EGTIG KMYFIQ G+V ++TK  + V  LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++
Sbjct:   58 EDETRSGFMQRQLSAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTTPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPQKIKRKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIFNLIAMMLLLCHWDGCLQFLVPMLQDFPTNCWVSINKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQRLHDYYEHRYQGKMFDEDSILGELNEPLREEIVNFNCRKLVASMPLFANADPSFVTAMLTKLKFEVFQPTDYIIREGTIGKKMYFIQHGVVSVLTKGNKEV-KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHK 576          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Match: lsamp (limbic system associated membrane protein [Source:Xenbase;Acc:XB-GENE-5759171])

HSP 1 Score: 574.704 bits (1480), Expect = 0.000e+0
Identity = 284/525 (54.10%), Postives = 386/525 (73.52%), Query Frame = 3
Query:  678 DSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
            D    ++ S +++ Q  +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI++ D + EIIL+P+ I R YLR+WF +D +SSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FPT  WV   K+ +  W E Y+++LFKAMSHML IGYGR  P S+S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQR+ +YYEHRYQGKMF+ED IL ELNE LRE+++N+NCR LVA++P F  AD SFV+ +++KL +EVFQP D II+EGTIG KMYFIQ G+V ++TK  + V  LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++
Sbjct:   30 DLYSNETRSGFMQRQLSAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTTPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPQKIKRKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIFNLIAMMLLLCHWDGCLQFLVPMLQDFPTNCWVSINKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQRLHDYYEHRYQGKMFDEDSILGELNEPLREEIVNFNCRKLVASMPLFANADPSFVTAMLTKLKFEVFQPTDYIIREGTIGKKMYFIQHGVVSVLTKGNKEV-KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHK 551          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Match: Hcn1 (hyperpolarization activated cyclic nucleotide gated potassium channel 1 [Source:MGI Symbol;Acc:MGI:1096392])

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 286/534 (53.56%), Postives = 395/534 (73.97%), Query Frame = 3
Query:  675 KDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLD 2264
            +D++  +    +++ QF S  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML+M++ NL+I+PV ++FFT+     W+IFN  SDTVFL D+ +NFRTG +  D S EIIL+PK+I  NYL+SWF +D ISSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV   ++ +  W +QY+++LFKAMSHML IGYG   P S+S+ WIT++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQ+I +YYEHRYQGK+F+E+ IL+ELN+ LRE+++N+NCR LVA +P F  AD +FV+ ++SKL +EVFQPGD II+EG +G KMYFIQ G+  +ITK  + +  L+DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+  +  F+ DL+
Sbjct:   71 EDAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNED-SSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILSELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQK--FQKDLN 599          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Match: Hcn2 (hyperpolarization-activated, cyclic nucleotide-gated K+ 2 [Source:MGI Symbol;Acc:MGI:1298210])

HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0
Identity = 282/524 (53.82%), Postives = 388/524 (74.05%), Query Frame = 3
Query:  681 SQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
             + + S +S+L+ QF +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI++ D + EIIL+P+ I + YLR+WF +D +SSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + IC L+ +MLLL HW+ C+QFL+P+L +FP++ WV    + +  W E Y+++LFKAMSHML IGYGR  P S+++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQ+I +YYEHRYQGKMF+ED IL ELN  LRE+++N+NCR LVA++P F  AD +FV+ +++KL +EVFQPGD II+EGTIG KMYFIQ G+V ++TK G     LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++
Sbjct:  126 GEPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHK 646          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Match: Hcn2 (hyperpolarization-activated, cyclic nucleotide-gated K+ 2 [Source:MGI Symbol;Acc:MGI:1298210])

HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0
Identity = 282/524 (53.82%), Postives = 388/524 (74.05%), Query Frame = 3
Query:  681 SQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
             + + S +S+L+ QF +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI++ D + EIIL+P+ I + YLR+WF +D +SSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + IC L+ +MLLL HW+ C+QFL+P+L +FP++ WV    + +  W E Y+++LFKAMSHML IGYGR  P S+++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQ+I +YYEHRYQGKMF+ED IL ELN  LRE+++N+NCR LVA++P F  AD +FV+ +++KL +EVFQPGD II+EGTIG KMYFIQ G+V ++TK G     LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++
Sbjct:  126 GEPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHK 646          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Match: Hcn4 (hyperpolarization-activated, cyclic nucleotide-gated K+ 4 [Source:MGI Symbol;Acc:MGI:1298209])

HSP 1 Score: 569.696 bits (1467), Expect = 0.000e+0
Identity = 281/525 (53.52%), Postives = 388/525 (73.90%), Query Frame = 3
Query:  678 DSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
            +++ +   S +++ QF +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML++++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI++ D + EIIL+P+ I   YL+SWF +D ISSIP+DYIFL V    +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV    + ++ W +QY+++LFKAMSHML IGYGR  P  +S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQRI +YYEHRYQGKMF+E+ IL EL+E LRE++IN+NCR LVA++P F  AD +FV+ +++KL +EVFQPGD II+EGTIG KMYFIQ G+V ++TK G   T L+DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++
Sbjct:  203 EAEVRLGQSGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVEDNT-EIILDPQRIKMKYLKSWFVVDFISSIPVDYIFLIVETRIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSINGMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHK 724          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Match: Hcn3 (hyperpolarization-activated, cyclic nucleotide-gated K+ 3 [Source:MGI Symbol;Acc:MGI:1298211])

HSP 1 Score: 558.14 bits (1437), Expect = 0.000e+0
Identity = 271/512 (52.93%), Postives = 373/512 (72.85%), Query Frame = 3
Query:  693 QSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVY-AGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIG 2213
            +S     + Q  +  QP+ NK +L++FGS  AV  E++R +    WIIHP S FRFYWDL ML++++ NLI+LPV ++FF +     W++FN  SDT FL D+ +NFRTGI++ ++  EI+L P+ I   YLR+WF +DLISSIP+DYIFL V         VY   + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP++ WV   ++ +  W  QY+ +LFKAMSHML IGYG+  P  + + W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQRI  YYEHRYQGKMF+E+ IL EL+E LRE++IN+ CR LVA +P F +AD SFV+ V++KL +EVFQPGDL+++EG++G KMYFIQ G++ ++ + G   T L+DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F AVLE +P+MRR  E+VA +RL +IG
Sbjct:   38 ESAPEPKRRQLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVV-EEGAEILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSMNRMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLAR-GARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLRRIG 547          
BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Match: sp|Q9JKB0|HCN1_RAT (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 OS=Rattus norvegicus OX=10116 GN=Hcn1 PE=2 SV=1)

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 286/534 (53.56%), Postives = 395/534 (73.97%), Query Frame = 3
Query:  675 KDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLD 2264
            +D++  +    +++ QF S  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML+M++ NL+I+PV ++FFT+     W+IFN  SDTVFL D+ +NFRTG +  D S EIIL+PK+I  NYL+SWF +D ISSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV   ++ +  W +QY+++LFKAMSHML IGYG   P S+S+ WIT++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQ+I +YYEHRYQGK+F+E+ IL+ELN+ LRE+++N+NCR LVA +P F  AD +FV+ ++SKL +EVFQPGD II+EG +G KMYFIQ G+  +ITK  + +  L+DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+  +  F+ DL+
Sbjct:   71 EDAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNED-SSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILSELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQK--FQKDLN 599          
BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Match: sp|O88704|HCN1_MOUSE (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 OS=Mus musculus OX=10090 GN=Hcn1 PE=1 SV=1)

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 286/534 (53.56%), Postives = 395/534 (73.97%), Query Frame = 3
Query:  675 KDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLD 2264
            +D++  +    +++ QF S  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML+M++ NL+I+PV ++FFT+     W+IFN  SDTVFL D+ +NFRTG +  D S EIIL+PK+I  NYL+SWF +D ISSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV   ++ +  W +QY+++LFKAMSHML IGYG   P S+S+ WIT++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQ+I +YYEHRYQGK+F+E+ IL+ELN+ LRE+++N+NCR LVA +P F  AD +FV+ ++SKL +EVFQPGD II+EG +G KMYFIQ G+  +ITK  + +  L+DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+  +  F+ DL+
Sbjct:   71 EDAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNED-SSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILSELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQK--FQKDLN 599          
BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Match: sp|O60741|HCN1_HUMAN (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 OS=Homo sapiens OX=9606 GN=HCN1 PE=1 SV=3)

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 286/534 (53.56%), Postives = 394/534 (73.78%), Query Frame = 3
Query:  675 KDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLD 2264
            +D++  +    +++ QF S  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML+M++ NL+I+PV ++FFT+     W+IFN  SDTVFL D+ +NFRTG +  D S EIIL+PK+I  NYL+SWF +D ISSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV   ++ +  W +QY+++LFKAMSHML IGYG   P S+S+ WIT++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQ+I +YYEHRYQGK+F+E+ IL ELN+ LRE+++N+NCR LVA +P F  AD +FV+ ++SKL +EVFQPGD II+EG +G KMYFIQ G+  +ITK  + +  L+DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+  +  F+ DL+
Sbjct:   82 EDAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNED-SSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQK--FQKDLN 610          
BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Match: sp|Q9MZS1|HCN1_RABIT (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 OS=Oryctolagus cuniculus OX=9986 GN=HCN1 PE=2 SV=2)

HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0
Identity = 286/534 (53.56%), Postives = 394/534 (73.78%), Query Frame = 3
Query:  675 KDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLD 2264
            +D++  +    +++ QF S  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML+M++ NL+I+PV ++FFT+     W+IFN  SDTVFL D+ +NFRTG +  D S EIIL+PK+I  NYL+SWF +D ISSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV   ++ +  W +QY+++LFKAMSHML IGYG   P S+S+ WIT++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQ+I +YYEHRYQGK+F+E+ IL ELN+ LRE+++N+NCR LVA +P F  AD +FV+ ++SKL +EVFQPGD II+EG +G KMYFIQ G+  +ITK  + +  L+DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+  +  F+ DL+
Sbjct:   18 EDAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNED-SSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQK--FQKDLN 546          
BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Match: sp|Q9JKA9|HCN2_RAT (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Rattus norvegicus OX=10116 GN=Hcn2 PE=1 SV=3)

HSP 1 Score: 575.474 bits (1482), Expect = 0.000e+0
Identity = 281/515 (54.56%), Postives = 384/515 (74.56%), Query Frame = 3
Query:  681 SQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIG 2213
             + + S +S+L+ QF +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI++ D + EIIL+P+ I + YLR+WF +D +SSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + IC L+ +MLLL HW+ C+QFL+P+L +FP++ WV    + +  W E Y+++LFKAMSHML IGYGR  P S+++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQ+I +YYEHRYQGKMF+ED IL ELN  LRE+++N+NCR LVA++P F  AD +FV+ +++KL +EVFQPGD II+EGTIG KMYFIQ G+V ++TK G     LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG
Sbjct:  126 GEPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIG 637          
BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Match: A0A1Z1R0Y6 (Cyclic nucleotide gated channel 1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 1347.41 bits (3486), Expect = 0.000e+0
Identity = 717/721 (99.45%), Postives = 718/721 (99.58%), Query Frame = 3
Query:  465 MSGDKINSNLIPHNRWNQFRSRFLQLGSHNSTSKIASMTDVGFYCSNEKLTQKRLSDTTGANNLDLNTDEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSXXXXXXXXXXXXXKSFNGSLKKPKESRRKSVVKLGLHKLGLIKSKSNNSLVEKKDNPNSNVITPKKEKHLDIXXXXXXXXXXXXXXXXVRSPDGLKNTHFKISFDMA 2627
            MSGDKINSNLIPHNRWNQFRSRFLQLGSHNSTSKIASMTDVGFYCSNEKLTQKRLSDTTGANNLDLNTDEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTLRILRLAKLLSMLRLLRLSRLVR VSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTW+LFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYA FVGHAAALIQSFDTSKRLYREKFKQVEEYMTY KLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSDDENDNAEDNGNDKSFNGSLKKPKESRRKSVVKLGLHKLGLIKSKSNNSLVEKKDNPNSNVITPKKEKHLDIEKEKAKSLSKESLNLLVRSPDGLKNTHFKISFDMA
Sbjct:    1 MSGDKINSNLIPHNRWNQFRSRFLQLGSHNSTSKIASMTDVGFYCSNEKLTQKRLSDTTGANNLDLNTDEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTLRILRLAKLLSMLRLLRLSRLVRCVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWALFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYASFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYCKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSDDENDNAEDNGNDKSFNGSLKKPKESRRKSVVKLGLHKLGLIKSKSNNSLVEKKDNPNSNVITPKKEKHLDIEKEKAKSLSKESLNLLVRSPDGLKNTHFKISFDMA 721          
BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Match: A0A267GGH4 (Cyclic nucleotide-binding domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003625g4 PE=4 SV=1)

HSP 1 Score: 883.634 bits (2282), Expect = 0.000e+0
Identity = 447/618 (72.33%), Postives = 523/618 (84.63%), Query Frame = 3
Query:  630 SDTTGANNLDLNTDEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSXXXXXXXXXXXXXKSFN-----GSLKK---PKESRRKSVVKLGLHKLGL-IKSKSNNSL 2456
            S T   ++L+L   E     KQSTSSYLKEQF +FFQPSDNKLA+KLFG+KNA+++EK+RQQ+  KWIIHPCS+FRFYWDL MLV+LI NL++LPV +SFF D +  QW+IFNC SDT+FL+DIAVNFRTG++  D ++EI+L+PK+IA++Y++SWFFLDLISSIP+DYIFL +N+  N    ++AG+ LRILRLAKLLS+LRLLRLSRLVRYVSQWEEF  IASK  GI KLVL+M+LLGHWNAC QFLIP L +FP +SWV K  L+ ++WF QYTW+LFKAMSHMLSIGYG+ PPTSISEAWITI+SMMTG++CYALFVGHAAALIQSFDTSKRLYREKFKQVEEYM YRKLPRALRQRIANYYEHRYQGKMFNE+ IL+EL+ECLREQ+INYNCRALVAAVPFFTYADQ FVSEVV++L YEVFQPGDLIIKEGTIGTKMYFIQEGIVDIIT+DGEV TSLSDGSYFGEICLLTNA+R A+VRAE YC+LYSL+ E F +VL+NYPLMRRTMESVAAERLSKIG NP ++++R D K+DL++VKEIV+ V+P  SDD +D+        +       G  KK   P   RRKSVVKLGL KLGL  KSKS  +L
Sbjct:  275 SATAVGDDLELGELE---DPKQSTSSYLKEQFFAFFQPSDNKLAMKLFGNKNALLKEKRRQQQSGKWIIHPCSNFRFYWDLLMLVLLITNLVVLPVAISFFNDDLSPQWIIFNCVSDTIFLSDIAVNFRTGVITNDFAEEIVLDPKMIAQHYMKSWFFLDLISSIPMDYIFLVLNQRNNMSQLMHAGRALRILRLAKLLSLLRLLRLSRLVRYVSQWEEFFQIASKCFGIIKLVLIMMLLGHWNACFQFLIPFLNDFPPDSWVAKRGLKEAHWFRQYTWALFKAMSHMLSIGYGQHPPTSISEAWITIVSMMTGSSCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFNENDILSELSECLREQIINYNCRALVAAVPFFTYADQDFVSEVVTRLKYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITRDGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLYSLERENFLSVLDNYPLMRRTMESVAAERLSKIGQNPQLVSSRADLKEDLNLVKEIVNQVTPATSDDNDDSCGGGAGAGACGGSAVCGDGKKSSPPHTERRKSVVKLGLQKLGLSSKSKSRGNL 889          
BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Match: A0A267GPW9 (Cyclic nucleotide-binding domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003625g3 PE=4 SV=1)

HSP 1 Score: 882.478 bits (2279), Expect = 0.000e+0
Identity = 447/618 (72.33%), Postives = 523/618 (84.63%), Query Frame = 3
Query:  630 SDTTGANNLDLNTDEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSXXXXXXXXXXXXXKSFN-----GSLKK---PKESRRKSVVKLGLHKLGL-IKSKSNNSL 2456
            S T   ++L+L   E     KQSTSSYLKEQF +FFQPSDNKLA+KLFG+KNA+++EK+RQQ+  KWIIHPCS+FRFYWDL MLV+LI NL++LPV +SFF D +  QW+IFNC SDT+FL+DIAVNFRTG++  D ++EI+L+PK+IA++Y++SWFFLDLISSIP+DYIFL +N+  N    ++AG+ LRILRLAKLLS+LRLLRLSRLVRYVSQWEEF  IASK  GI KLVL+M+LLGHWNAC QFLIP L +FP +SWV K  L+ ++WF QYTW+LFKAMSHMLSIGYG+ PPTSISEAWITI+SMMTG++CYALFVGHAAALIQSFDTSKRLYREKFKQVEEYM YRKLPRALRQRIANYYEHRYQGKMFNE+ IL+EL+ECLREQ+INYNCRALVAAVPFFTYADQ FVSEVV++L YEVFQPGDLIIKEGTIGTKMYFIQEGIVDIIT+DGEV TSLSDGSYFGEICLLTNA+R A+VRAE YC+LYSL+ E F +VL+NYPLMRRTMESVAAERLSKIG NP ++++R D K+DL++VKEIV+ V+P  SDD +D+        +       G  KK   P   RRKSVVKLGL KLGL  KSKS  +L
Sbjct:  279 SATAVGDDLELGELE---DPKQSTSSYLKEQFFAFFQPSDNKLAMKLFGNKNALLKEKRRQQQSGKWIIHPCSNFRFYWDLLMLVLLITNLVVLPVAISFFNDDLSPQWIIFNCVSDTIFLSDIAVNFRTGVITNDFAEEIVLDPKMIAQHYMKSWFFLDLISSIPMDYIFLVLNQRNNMSQLMHAGRALRILRLAKLLSLLRLLRLSRLVRYVSQWEEFFQIASKCFGIIKLVLIMMLLGHWNACFQFLIPFLNDFPPDSWVAKRGLKEAHWFRQYTWALFKAMSHMLSIGYGQHPPTSISEAWITIVSMMTGSSCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFNENDILSELSECLREQIINYNCRALVAAVPFFTYADQDFVSEVVTRLKYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITRDGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLYSLERENFLSVLDNYPLMRRTMESVAAERLSKIGQNPQLVSSRADLKEDLNLVKEIVNQVTPATSDDNDDSCGGGAGAGACGGSAVCGDGKKSSPPHTERRKSVVKLGLQKLGLSSKSKSRGNL 893          
BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Match: A0A4Z2DGN8 (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_001166 PE=4 SV=1)

HSP 1 Score: 868.611 bits (2243), Expect = 0.000e+0
Identity = 428/537 (79.70%), Postives = 486/537 (90.50%), Query Frame = 3
Query:  690 KQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSS-VSP 2297
            KQSTSSYLKEQF +FFQPSDNKLA+KLFGSKNA+++EK+RQ ++ KW+IHPCS+FRFYWDL ML++LIANLIILPV +SFF D + I W+IFN  SD VF+ADIAV FRTG++  D +DEIILNPK IAR+YL+SWF LD ISSIP+DY++L  N+ ++Y+ F  AG+TLRILRLAKLLSMLRLLRL+RLVRYVSQWEEFLNIASKF+GI  LVLLMLLLGHWNAC+Q+LIP+LMEFP +SWV +CKL+++ WF+QYTW+LFKAMSHMLSIGYGRFPPTSI EAWITI+SMM+GATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYM YRKLPRALRQRIANYYEHRYQGKMF+E QIL E +ECLREQVINYNCRALVAAVPFFTYADQ FVSEVV+KL +EVFQPGDLIIKEGTIG KMYFIQEGIVDIITKDGEV TSLSDGSYFGEI LLTNA+R A+V+A VY +LYSLD E F +VLENYPLMRRTMESVAAERL+KIG NP I++NRED K+DL +VKEIVSS V+P
Sbjct:  592 KQSTSSYLKEQFQAFFQPSDNKLAMKLFGSKNALLKEKRRQVQQGKWVIHPCSNFRFYWDLLMLMLLIANLIILPVAISFFNDDLSIHWIIFNSISDVVFIADIAVKFRTGVVANDYADEIILNPKEIARHYLKSWFVLDFISSIPMDYLYLIFNKKDHYNQFFSAGRTLRILRLAKLLSMLRLLRLTRLVRYVSQWEEFLNIASKFMGIFNLVLLMLLLGHWNACLQYLIPMLMEFPPDSWVKRCKLENADWFQQYTWALFKAMSHMLSIGYGRFPPTSIGEAWITIVSMMSGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEAQILNEFSECLREQVINYNCRALVAAVPFFTYADQDFVSEVVTKLKFEVFQPGDLIIKEGTIGNKMYFIQEGIVDIITKDGEVATSLSDGSYFGEITLLTNARRVASVKAVVYSNLYSLDRESFLSVLENYPLMRRTMESVAAERLNKIGQNPSIVSNREDLKEDLSLVKEIVSSAVTP 1128          
BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Match: A0A4E0S1I5 (Cyclic nucleotide and voltage-activated ion channel OS=Fasciola hepatica OX=6192 GN=D915_002800 PE=4 SV=1)

HSP 1 Score: 865.914 bits (2236), Expect = 0.000e+0
Identity = 439/584 (75.17%), Postives = 503/584 (86.13%), Query Frame = 3
Query:  603 NEKLTQKRLSDTTGANNLDLNT---------------DEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSS-VSPMVS 2306
            NE+LT K    +T  NN +LN+               ++     K STSSYLKEQFL+FFQPSDNKLA+KLFGSKNA+++EK+RQ ++ KWIIHPCSSFRFYWDL MLV+LIANLIILPV +SFF D + I W+IFN  SD +F+ADIAV FRTG++  D +DEIILNPK IAR+YL+SWF LD ISSIP+DYI+L  N+ ++Y+ F  AG+TLRILRLAKLLSMLRLLRL+RLVRYVSQWEEFLNIASKF+GI  LVLLMLLLGHWNAC+Q+LIP+LMEFP +SWV +CKL+++ WF+QYTW+LFKAMSHMLSIGYGRFPP SI +AWITI+SMM+GATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYM YRKLPRALRQRIANYYEHRYQGKMF+E QIL E +ECLREQ+INYNCRALVAAVPFFTYADQ FVSEVV+KL +EVFQPGDLIIKEGT+G KMYFIQEGIVDIITKDGEV TSLSDGSYFGEICLLTNA+R A+V+A VY +LYSLD E F +VL+NYPLMRRTMESVAAERLSKIG NP I++NRED K+DL +VKEIVSS V+P  S
Sbjct:  420 NEQLTDK----STSTNNFNLNSHSTYSIAALADGNFVEQGSEMAKPSTSSYLKEQFLAFFQPSDNKLAMKLFGSKNALLKEKRRQAQQGKWIIHPCSSFRFYWDLLMLVLLIANLIILPVAISFFNDDLSIHWIIFNSISDIIFIADIAVKFRTGVVTNDYADEIILNPKEIARHYLKSWFVLDCISSIPMDYIYLIFNKKDHYNQFFSAGRTLRILRLAKLLSMLRLLRLTRLVRYVSQWEEFLNIASKFMGIFNLVLLMLLLGHWNACLQYLIPMLMEFPPDSWVKRCKLENADWFQQYTWALFKAMSHMLSIGYGRFPPISIGDAWITIVSMMSGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEAQILNEFSECLREQIINYNCRALVAAVPFFTYADQDFVSEVVTKLKFEVFQPGDLIIKEGTMGNKMYFIQEGIVDIITKDGEVATSLSDGSYFGEICLLTNARRVASVKAVVYSNLYSLDRESFLSVLDNYPLMRRTMESVAAERLSKIGQNPAIVSNREDLKEDLSLVKEIVSSAVTPEAS 999          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Match: hcn4l (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3-like [Source:NCBI gene;Acc:103030119])

HSP 1 Score: 585.489 bits (1508), Expect = 0.000e+0
Identity = 284/522 (54.41%), Postives = 387/522 (74.14%), Query Frame = 3
Query:  660 LNTDEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIG 2213
            L + E+  +++   + ++  Q  +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML++++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI+  D S EIIL+P++I   YLRSWF +D ISSIP+DYIFL V    +   F    + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP++ WV K K+ +  W +QY+++LFKAMSHML IGYG +PP  +++ W+TI+SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQRI +YYEHRYQGKMF+E+ IL ELNE LRE++I++NCR LVA +P F  AD +FV+ +++KL +EVFQPGD II+EGT+G KMYFIQ G++ ++TK G   T +SDGSYFGEICLLT  +R A+VRAE YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG
Sbjct:  166 LESGEQMDEERLYQAGFMHRQLGAMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLIMLLLMVGNLIIIPVGITFFKDEHTPAWIVFNVVSDTFFLVDLVLNFRTGIVKED-STEIILDPQLIKVRYLRSWFAVDFISSIPVDYIFLIVETRID-SDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIISFNCRKLVATMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTVGKKMYFIQHGVLTVLTK-GSKETKISDGSYFGEICLLTRGRRTASVRAETYCRLYSLSVDHFNEVLEEYPMMRRAFETVALDRLDRIG 684          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Match: hcn4l (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3-like [Source:NCBI gene;Acc:103030119])

HSP 1 Score: 585.104 bits (1507), Expect = 0.000e+0
Identity = 284/522 (54.41%), Postives = 387/522 (74.14%), Query Frame = 3
Query:  660 LNTDEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIG 2213
            L + E+  +++   + ++  Q  +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML++++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI+  D S EIIL+P++I   YLRSWF +D ISSIP+DYIFL V    +   F    + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP++ WV K K+ +  W +QY+++LFKAMSHML IGYG +PP  +++ W+TI+SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQRI +YYEHRYQGKMF+E+ IL ELNE LRE++I++NCR LVA +P F  AD +FV+ +++KL +EVFQPGD II+EGT+G KMYFIQ G++ ++TK G   T +SDGSYFGEICLLT  +R A+VRAE YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG
Sbjct:  145 LESGEQMDEERLYQAGFMHRQLGAMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLIMLLLMVGNLIIIPVGITFFKDEHTPAWIVFNVVSDTFFLVDLVLNFRTGIVKED-STEIILDPQLIKVRYLRSWFAVDFISSIPVDYIFLIVETRID-SDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIISFNCRKLVATMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTVGKKMYFIQHGVLTVLTK-GSKETKISDGSYFGEICLLTRGRRTASVRAETYCRLYSLSVDHFNEVLEEYPMMRRAFETVALDRLDRIG 663          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Match: hcn2b (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [Source:NCBI gene;Acc:103044493])

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 291/570 (51.05%), Postives = 401/570 (70.35%), Query Frame = 3
Query:  552 NSTSKIASMTDVGFYCSNEKLTQKRLSDTTGANNLDLNTDEK---DSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
            +  S++A  T      S       R+S +T         D +   D  + +   ++++ QF S  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W+IFN  SDT FL D+ +NFRTGI+  D + EIIL+PK I + YLR+WF +D ISSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP++ WV   K+ +  W E Y+++LFKAMSHML IGYGR  P S+S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQ+I +YYEHRYQGKMF+E+ IL ELNE LRE+++N+NCR LVA++P F  AD +FV+ +++KL +EVFQP D II+EGTIG KMYFIQ G+V ++TK G +   LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL ++G    I+ ++
Sbjct:  110 DGASELAPNTTPSTPASAPDRRDPRVSFSTAPGPTKTPEDAQLAGDDGEARDAQTFMQRQFSSMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKDETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYEDNT-EIILDPKQIKKKYLRTWFVVDFISSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPLDYIIREGTIGKKMYFIQHGVVSVLTK-GSIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRLGKKNSILMHK 676          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Match: hcn2b (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [Source:NCBI gene;Acc:103044493])

HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0
Identity = 291/570 (51.05%), Postives = 401/570 (70.35%), Query Frame = 3
Query:  552 NSTSKIASMTDVGFYCSNEKLTQKRLSDTTGANNLDLNTDEK---DSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
            +  S++A  T      S       R+S +T         D +   D  + +   ++++ QF S  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W+IFN  SDT FL D+ +NFRTGI+  D + EIIL+PK I + YLR+WF +D ISSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP++ WV   K+ +  W E Y+++LFKAMSHML IGYGR  P S+S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQ+I +YYEHRYQGKMF+E+ IL ELNE LRE+++N+NCR LVA++P F  AD +FV+ +++KL +EVFQP D II+EGTIG KMYFIQ G+V ++TK G +   LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL ++G    I+ ++
Sbjct:   62 DGASELAPNTTPSTPASAPDRRDPRVSFSTAPGPTKTPEDAQLAGDDGEARDAQTFMQRQFSSMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKDETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYEDNT-EIILDPKQIKKKYLRTWFVVDFISSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPLDYIIREGTIGKKMYFIQHGVVSVLTK-GSIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRLGKKNSILMHK 628          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Match: hcn1 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 [Source:NCBI gene;Acc:103022855])

HSP 1 Score: 574.704 bits (1480), Expect = 0.000e+0
Identity = 285/552 (51.63%), Postives = 400/552 (72.46%), Query Frame = 3
Query:  645 ANNLDLNTDEK-------DSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVY-AGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLD 2264
            AN++ + TD +       D+     +  +++ Q  +  QP  NK +L++FGS+ AV +E++R Q    WIIHP S FRFYWDL ML+M++ NLII+PV ++FF++     W++FN  SDT+FL D+ +NFRTGI+  ++S EIIL+PK+I  NYL+SWF +D +SSIP+DYIFL V +G  +   VY   + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV    + +  W +QY+++LFKAMSHML IGYG   P S+S+ WIT++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQ+I +YYEHRYQGK+F+ED IL ELN+ L+E+++N+NCR LVA +P F  AD +FV+ ++SKL +EVFQP D II+EGT+G KMYFIQ G+  +ITK  + +  L+DGSYFGEICLLT  +R A+VRA+ YC L+SL  + F  VLE YP+MRR  E+VA +RL +IG    ++  +  F+ DL+
Sbjct:   72 ANSVAVKTDREETMLGLEDADPAGRSHGFMQRQIGAMLQPGVNKFSLRMFGSQKAVEKEQERVQTAGYWIIHPYSDFRFYWDLIMLIMMMGNLIIIPVGITFFSEQTTTTWLVFNVASDTIFLVDLVMNFRTGIV-NEESSEIILDPKVIKMNYLKSWFVVDFLSSIPVDYIFLIVEKG--FDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNGMVNDSWGKQYSYALFKAMSHMLCIGYGARAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEDNILNELNDPLKEEIVNFNCRKLVATMPLFANADPNFVTGMLSKLKFEVFQPNDYIIREGTVGKKMYFIQHGVASVITKHNKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLFSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSLLLQK--FQKDLN 617          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007865.1 (pep scaffold:Pmarinus_7.0:GL480431:10244:18565:-1 gene:ENSPMAG00000007113.1 transcript:ENSPMAT00000007865.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 245.358 bits (625), Expect = 2.226e-74
Identity = 136/287 (47.39%), Postives = 199/287 (69.34%), Query Frame = 3
Query:  864 WDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEF-LNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWV--------------------VKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFK 1661
            WD+ ML++++ NLI++PV ++FF +     W++FN  SDT FL D+ +NFRTGI++ D +D IIL+P++I   YL+SWF +D +SSIP+DYIFL V    +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE   ++AS  + I  L+ +MLLL HW+ C+QFL+P+L EFP + W+                    +    Q+  W +QY+++LFKAMSHML IGYG+  P S+++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK +
Sbjct:    1 WDIIMLLLMVGNLIVIPVGITFFHEEDTTAWIVFNVLSDTCFLVDLVLNFRTGIVVEDNTD-IILDPQVIKMRYLKSWFLVDFVSSIPVDYIFLIVETRIDSEMYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEMTYDLASAVVRIVNLIAMMLLLCHWDGCLQFLVPMLQEFPHDCWISLNGMVVGLAASRTHLRFFAITPVCQNDSWGKQYSYALFKAMSHMLCIGYGQRAPVSMADLWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKMQ 285          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005594.1 (pep scaffold:Pmarinus_7.0:GL476331:707593:738342:1 gene:ENSPMAG00000005049.1 transcript:ENSPMAT00000005594.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 166.007 bits (419), Expect = 3.677e-43
Identity = 133/495 (26.87%), Postives = 228/495 (46.06%), Query Frame = 3
Query:  789 VIQEKKRQQKEA-KWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQ------------WVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLM---LLLGHWNACIQFLIPVLMEFPTES-------WVVKCKLQHSYWF------------EQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQ-GKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEIC--LLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYP 2159
            V+ E K Q     KW I   S F+  WD  +L+++I   I  P   +F     +++              I +   D +F+ DI +NFRT  +  +K++E++ +P  IA +Y + WF +D++++IP D +      G        +G+T  ++ L K   +LRL+R++R +   S++           G   LVLLM    L+ HW ACI + I   ME P +S       W+ +   Q    +            ++Y  +L+   S + S+G+G   P +  E   +I  M+ G+  YA   G+ +A+IQ   +    Y  +  +V+E++ + ++P  LRQR+  Y++H +      + + +L    ECL+  +  +  R L+ +   F  A +  +  +  K       PGD ++  G + T MYF+  G ++I+ +D  VV  L     FGE         K  A VRA  YC L+ +  E    VL+ YP
Sbjct:   75 VLPEYKLQAPRIHKWTILHYSPFKAVWDWLILLLVIYTAIFTPYTAAFLLSDQQVENERQKCGYSCNPLNIVDLMVDIMFMVDIFINFRTTYI--NKNEEVVSHPGKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSG--------SGETTTLIGLLKTARLLRLVRVARKLDRYSEY-----------GAAVLVLLMCTFALIAHWLACIWYAIGN-MERPVDSLAKDRIGWLDQLGGQIGKPYNDTDTSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNYEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNMVLKGFPECLQADICLHLNRTLLESCKAFNGASKGCLRALAMKFKTTHAPPGDTLVHSGDVITAMYFLSRGSIEILRED-IVVAILGKNDIFGEPVNQYSRPGKSSADVRALTYCDLHKIVREDMLEVLDMYP 546          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Match: kcnh1b (potassium voltage-gated channel, subfamily H (eag-related), member 1b [Source:ZFIN;Acc:ZDB-GENE-121128-4])

HSP 1 Score: 156.762 bits (395), Expect = 2.399e-39
Identity = 131/509 (25.74%), Postives = 216/509 (42.44%), Query Frame = 3
Query:  750 NKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFV--------YAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKF-----IGICKLVLLMLLLG---HWNACIQFLI---PVLME----FPTESWVVKC--KLQHSYWFEQYTW------------SLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQ-GKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTN--AKRCATVRAEVYCSLYSLDSEQFKAVLENY 2156
            ++LA  L    + + Q K+   K    II    +F+  WD  +L++     I++P  VSF T    + W++ +   D +FL DI +NF T       + E+I +PK+I  NYL++WF +DL+S +P D I    N  EN    V        +  ++   L  A      + +        V +      +A K       G   LVLL+ + G   HW ACI + I    V+ E        SW+ +    +   Y F    W            SL+  M+ + SIG+G   PT+  E    +  MM G+  YA   G+   + Q    +   Y E    V +++   ++P+ L +R+ +Y    +   K  + +++L    + +R  +  +  R +    P F  A    +  +  +       PGDLI   G     + F+  G +++I +D EVV  L  G  FG++       A  CA VRA  YC L+ +  +    VL+ Y
Sbjct:  162 SRLAEVLQLGSDILPQYKQETPKTPPHIILHYCAFKTTWDWIILILTFYTAIMVPYNVSFKTKQNNVAWLVVDSVVDVIFLVDIVLNFHT--TFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDII----NAFENVDEVVRAAQIRGPFGSRSPSRLLDAWPRVAPQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWLACIWYSIGDYEVIDEATNLIRKHSWLYQLGETIGTPYHFNGTQWEGGPSKDAVYISSLYFTMTSLTSIGFGNIAPTTDGEKIFAVAMMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLHICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQTHHCAPGDLIYHAGESVDTLCFVVSGSLEVI-QDDEVVAILGKGDVFGDVFWKERVIAPSCANVRALTYCDLHVIRRDALVKVLDFY 663          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005922.1 (pep scaffold:Pmarinus_7.0:GL476456:333240:381928:-1 gene:ENSPMAG00000005344.1 transcript:ENSPMAT00000005922.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 117.087 bits (292), Expect = 4.140e-27
Identity = 120/502 (23.90%), Postives = 228/502 (45.42%), Query Frame = 3
Query:  750 NKLALK--LFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQ----WVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIP-VLMEF-PTESWVVKC------KLQHSYWFEQ----------YTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQ-GKMFNEDQILTELNECLREQV-INYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFG------EICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYP 2159
            NKL +   +FG K ++ + K    +++++I+    +F+  WDL +L+      + +P  V F      I       + +   + +F+ DI +NFRT  +   KS +++ + + I  +Y+ +WFF+DLI+++P D ++ A N             T  +  L  +  +  L  L  L RY SQ+   +        +  L+ +  LL HW ACI + I    +E     SW +        KL+  +              Y  SL+ A+S + S+G+G     + +E   ++ +M+ GA  +A+  G+  A+IQ   + +  Y  + K +++++   +LP+ L+QR+  Y++  +      +  ++L +  + LR  + ++ N   L  A+  F  A +  +  +   +      PG+ +I++G      YF+  G ++++ KD  V+  L  G   G      +  L TNA     V+A  YC L  +       VL+ YP
Sbjct:   21 NKLKINNNVFGEKPSLPEYKVAAIQKSRFILLHYGTFKAGWDLLILLATFYVAVTVPYNVCFSETVENISDPRSTAVVDISVEILFIIDILLNFRTTYV--SKSGQVVYDGRSICVHYVTTWFFIDLIAALPFDLLY-AFN----------VSVTTLVHLLKTVRLLRLLRLLQNLDRY-SQYSTVV--------LTLLMFMFGLLAHWMACIWYKIGRAEIEINDRHSWDIGWLHELGKKLETPFHTNNTGGGPSTRSAYIASLYFALSSLTSVGFGNVSANTDAEKIFSVCAMLIGALMHAVVFGNVTAIIQRMYSRRSQYHTRTKDLKDFIRVHRLPKQLKQRMLEYFQTTWSVNNGIDTHELLKDFPDELRADIAMHMNKEILQLAI--FESASRGCLRSLSLSIKPSFCAPGEFLIRQGDALQAFYFVCSGSMEVL-KDDMVLAILGKGDLIGSDLSSKDQVLKTNAD----VKALTYCDLQCIHLRGLYDVLDLYP 493          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Match: kcnh8 (potassium voltage-gated channel, subfamily H (eag-related), member 8 [Source:ZFIN;Acc:ZDB-GENE-060503-204])

HSP 1 Score: 105.145 bits (261), Expect = 3.710e-24
Identity = 101/435 (23.22%), Postives = 204/435 (46.90%), Query Frame = 3
Query:  795 QEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRI----QWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTE------SWV--VKCKLQHSYW----------FEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQ-GKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSD 2030
            + K    + ++ I+    +F+  WD  +L+      + +P  V F     +       ++ +  S+ +F+ DI +NFRT  +    S +++ N + I  +Y+ +WF +DLI+++P D + +  + GE    FV+  KT+R+LRL +LL  L            SQ+          + +  L+ +  LL HW ACI ++I       T+       W+  ++ +L   ++             Y  SL+  +S + S+G+G     +  E   +I +M+ GA  +A+  G+  A+IQ   + + LY  + + ++E++   +LP  L+QR+  Y++  +      + +++L +  + LR  V  +  + ++  +P F  A +  +  +   +      PG+ +I++G      YFI  G ++ + KDG V+  L +
Sbjct:    3 EYKVAAAQRSRLILLHYGTFKAGWDWLILLATFYVAVTVPYNVCFLNSDEQCTSSRSTMVSDITSEILFIIDIVLNFRTTYV--SGSGQVVYNGRSICLHYVTTWFPIDLIAALPFDLLVIVRSWGERGTSFVHLLKTVRLLRLLRLLQKLDRY---------SQYSA--------VVLAMLMCMFALLAHWMACIWYIIGFEEMKSTDLVTHQIGWLQELQRRLVAPHYPNITQGMPPIRSAYITSLYFTLSSITSVGFGNVSANTDGEKIFSICAMLIGALMHAVVFGNVTAIIQRMYSRRSLYLTRTRDLKEFIRIHRLPHQLKQRMLEYFQTTWSVNNGIDTNELLKDFPDELRADVTMHLNKEML-QLPLFESASRGCLRSLSLNVKTTFCAPGEYLIRQGDALQAFYFILSGSMEAL-KDGTVLAILGE 416          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Yeast
Match: BCY1 (Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA); PKA is a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation [Source:SGD;Acc:S000001295])

HSP 1 Score: 65.855 bits (159), Expect = 1.056e-11
Identity = 32/90 (35.56%), Postives = 49/90 (54.44%), Query Frame = 3
Query: 1878 SEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVL 2147
            +++   L  +++QPG+ II+EG  G   Y I+ G VD+  K   V+  L D  YFGE+ LL +  R ATV A     + +L    F+ +L
Sbjct:  312 AKLADALDTKIYQPGETIIREGDQGENFYLIEYGAVDVSKKGQGVINKLKDHDYFGEVALLNDLPRQATVTATKRTKVATLGKSGFQRLL 401          

HSP 2 Score: 60.4622 bits (145), Expect = 5.243e-10
Identity = 33/86 (38.37%), Postives = 47/86 (54.65%), Query Frame = 3
Query: 1920 GDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTM 2177
            G  IIK+G  G   Y +++G VD    D +V +S   GS FGE+ L+ N+ R ATV A   C L++LD   F+ +L      +R M
Sbjct:  208 GATIIKQGDQGDYFYVVEKGTVDFYVNDNKVNSS-GPGSSFGELALMYNSPRAATVVATSDCLLWALDRLTFRKILLGSSFKKRLM 292          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Match: EDO34316 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPS0])

HSP 1 Score: 514.612 bits (1324), Expect = 3.675e-174
Identity = 260/495 (52.53%), Postives = 366/495 (73.94%), Query Frame = 3
Query:  729 SFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIG 2213
            S+ +P DNK+ +K+FGSK A+  E+ R  + A W+IHP S FR YWD+++L++L+ NL  LPV++SFF D++  +W+ FN  SDT FL DI +NFRTG+L+    ++ IL+PKIIA+ YL++WFF+DLISS+P+DYI  A  +       + A +TL++LR AKLL +L+LLRLSRLVRYV Q+EE LN+    I    LV ++LL+ HWN C+QFL+P L +FP  SWV    L  + W+EQY WSLFKAMSHML IGYGR+PP +I+E W+T  SM+TGAT YA+F+ +    IQ  D+  R YREK +Q+EEYM+YR+LP  LR R+  YY+HRYQG+MF+E++IL E+++ LREQ+INYNCR LV +VPFFT A+  FVS ++++L +EV+  GD+I++EG +GT+MYF++EG+V  +T  G+    L DG+YFGEICLLTNA+R A+V A+  C ++ L++E F+ V++ +P MR  ME VA +RL+K+G
Sbjct:    7 SWLKPMDNKMNMKVFGSKRAMKDEQLRYSR-AGWVIHPTSIFRLYWDMWVLLLLLINLFALPVLISFFADNVSARWIAFNAVSDTAFLLDILLNFRTGVLVHGSPNKFILDPKIIAKRYLKTWFFIDLISSLPIDYIVEAATQSST-KSLIGATRTLKLLRFAKLLGLLKLLRLSRLVRYVQQYEEILNVTRSVIRFINLVSIILLIAHWNGCLQFLVPYLQDFPETSWVSIHNLMDNDWWEQYCWSLFKAMSHMLCIGYGRYPPQNIAEVWVTTFSMLTGATFYAMFIAYCINFIQQLDSPGRNYREKIQQIEEYMSYRRLPVELRDRMTKYYDHRYQGRMFDEEKILHEISKPLREQIINYNCRDLVQSVPFFTEAEPDFVSAIITRLSFEVYLEGDIIVREGELGTEMYFLREGVVS-VTVGGKHANELCDGAYFGEICLLTNARRTASVTAKTVCDVFILNAEHFRDVVDEFPTMRILMEIVAEDRLNKMG 498          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Match: EDO49064 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI02])

HSP 1 Score: 498.819 bits (1283), Expect = 3.405e-168
Identity = 251/495 (50.71%), Postives = 359/495 (72.53%), Query Frame = 3
Query:  747 DNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLT-NAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDI 2228
            DNKLALKLFG+K AV+ E++RQ ++ K +IHP S+FR+YWD+ +++ +  ++++LPV ++F +D + I W+I N  SD  F+ DI +NFRTGI+  +  +E+IL+ K+I+  YLR WF +DL SS+P DY +   +        + A + LRIL+LAKLLS+LRLLR+SRLVRY++++EE LNIA   + I KL+  ML+L HWN CIQF +P L EFP +SWV    L+ +   EQY+WSLF+A+SHML IGYG +PP ++++ W+T+ SM  GAT YA+F+G  ++LI S D+S RL+ EK  QVEEYM YRKLP  +R ++ ++YEHR+  K+F+ED ILTEL++ LRE ++ +N + L+  VPFF+ A  SF++++V+KL +EVF  GD I + G  G KMYFIQ+GIVDI+T++G + TSL DGS+FGEICLLT  A+R A+VRA   C +YSL +  F  VL++YP M+  +E VA ERLS++G  P +
Sbjct:    1 DNKLALKLFGNKAAVMLEQRRQSQQGKGVIHPFSTFRWYWDILLIIFIFMHVLLLPVSIAFLSDDLSIHWLILNGVSDVFFVVDIFLNFRTGIVDPNNQEEVILDKKVISMMYLRGWFIIDLASSLPFDYAYFIASSTTEEQTLLRASRALRILKLAKLLSLLRLLRVSRLVRYMTRFEELLNIAKGQLRIMKLICCMLVLSHWNGCIQFFVPYLQEFPDDSWVSTSNLKTASPGEQYSWSLFRALSHMLCIGYGHYPPQNLTDLWLTVCSMTAGATFYAVFIGIMSSLIMSIDSSGRLFNEKLNQVEEYMRYRKLPLRIRLQVQDFYEHRFHHKLFDEDAILTELSKNLRETILVHNIKPLLTTVPFFSGASISFITDIVTKLKFEVFLNGDYICRSGHRGDKMYFIQKGIVDILTREGALATSLGDGSHFGEICLLTKEARRVASVRAATTCDVYSLSATHFHEVLQDYPEMKSVLEEVAKERLSRLGLKPKL 495          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Match: EDO35393 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLM8])

HSP 1 Score: 159.458 bits (402), Expect = 5.123e-42
Identity = 127/475 (26.74%), Postives = 233/475 (49.05%), Query Frame = 3
Query:  858 FYWDLFMLVMLIANL--IILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILN--PKIIARNYLRSW-FFLDLISSIPLD--YIFLA------VNRGENYHHF-VYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQH------SYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMF-NEDQILTELNECLREQV-INYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDG-EVVTSLSDGSYFGEICLLTNA----KRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERL 2201
            ++W L + + ++ N   IIL        D +   W+I +   D +++ADI V+ RTG L     +E IL      + R+YL ++ F+LD  + IPLD  YIF+       +NR   +H F  +  +T                              F N+    + +  LV  +LL+ HWNACI F++   + F ++ WV     Q       +     Y +S + +   + +IG    PP S  E  I  +  + G   +A  VG+   +I + + ++  ++ K   ++ YM + K+P+ L++R+  ++++ +  K   +E++IL  L + LR ++ IN +  +L   V  F   +  F+ E+V +L  ++F PGD + ++G +G +MY +  G ++++++ G ++   L  GSYFGEI +L+ +    +R A+VR+  Y  L+ L       VL+ YP ++  +E +A E+L
Sbjct:    6 YFWLLVVSLAVLYNCWAIILRTAFPQINDKITYIWLILDYSCDLIYIADILVSMRTGFL-----EEGILQTCSTKMRRHYLHTYEFYLDAGALIPLDIAYIFIEHEPAFRINRILKFHRFWHFLDRTESRTT-------------------------FPNV----VRLASLVQFILLIIHWNACIYFIVSREIGFGSDVWVYPGVRQEILNSSENTISRMYIYSFYWSTLTLTTIGEVP-PPYSEVEYIIVTLDYLIGVLLFATIVGNVGNIITNLNATRLDFQNKMDGIKAYMRFHKIPQHLQRRVIKWFDYLWTYKKHPDEEEILLSLPDKLRAEIAINVHLDSL-RKVAIFQDCEAGFLCELVLRLRSQLFSPGDYVCRKGEVGREMYIVNRGKLEVVSEHGTKIYAVLEAGSYFGEISVLSMSSAGNRRTASVRSVGYTELFCLAKNDLMEVLDEYPNIKEKIEKIAKEKL 444          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Match: EDO35376 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLM9])

HSP 1 Score: 153.295 bits (386), Expect = 5.443e-40
Identity = 128/474 (27.00%), Postives = 225/474 (47.47%), Query Frame = 3
Query:  831 IIHPCSSFRFYWDLFMLVMLIANLIILPVIVSF--FTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSW-FFLDLISSIPLD--YIFLAV------NRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWV-VKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRF-----PPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKM-FNEDQILTELNECLREQV-INYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAK-----RCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTME 2180
            ++ P  +F F W L + + +I N   L V V+F    ++     +  +   D++F  D  V FR G L   +   +++    + + Y  S+ F LDLIS +P D  Y++L V      NR    H F+                                  E  +   K   + KL+  + L+ HW AC+ F++     F T+ W+  +   Q S    QY +SL+++   M ++G G       P T ++  ++ I++ +TG   +A  VG+A  +I     S+  Y  K   ++EY+   +LP  L++R+ +++++ ++ K   NE ++  +LN+  + ++ I+ N   L+  V  F   D  F+ E+V KL   +  PGD I ++G  G +MY + +G ++++ +   V+ +LS GS+FGEI LL N K     R A+VR+  +  L+ L     + VLE YP  +  ME
Sbjct:    2 VLDPSGTFYFLWLLTVSLGVIYNYWALIVYVAFPSVHEANLKTCIAVDYTFDSIFFLDTLVQFRVGFL---EHGVMVVGCWKLTKKYGCSFGFMLDLISILPFDVLYLYLGVLPILRFNRLFKAHRFLL----------------------------FCDRGEIYSGRPKLFNLAKLIHYLFLIIHWVACVYFILSRYEGFGTDEWLHPRLDGQLSKLSMQYLYSLYRSSVSMTTVGAGVIGTIATPRTELTLCFV-IVTYLTGVLIFATIVGNAGDMIVEMRRSRERYLRKLNGMKEYIEAYQLPAHLKKRVIHWFDYLWRHKRDMNEQELFHKLNDNFKAEIAIHVNLDTLIR-VEMFHDCDPGFLHELVLKLRPVICSPGDFICRQGEKGREMYIVNKGSLEVLDEKETVLATLSAGSHFGEISLL-NMKGIGNLRTASVRSVGFSDLFQLSKTDLEEVLEFYPQAKEQME 441          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Match: EDO34633 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNW2])

HSP 1 Score: 149.058 bits (375), Expect = 1.896e-38
Identity = 120/461 (26.03%), Postives = 219/461 (47.51%), Query Frame = 3
Query:  858 FYWDLFMLVMLIANLIILPVIVSFFTDSMRIQ--WVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFF-LDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSY--WFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKM-FNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTS-LSDGSYFGEICLLT----NAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSK 2207
            F+W   + V ++ N + +     F    +R    W + +   D ++  DI V FRT  L       ++ + K + +NYL +  F LD+IS +P D+++  +            G    + RL +LL + R+++L +     S +   L   +       +VL++LL+ HWNAC  F I   + F ++ WV      ++Y     QY +S + + + M+  G    PP +  E    +  +  G   +A  VG   A++     ++  +      +++YM   K+   L++R+ ++ ++ +  K   + ++IL +L E LR Q+  +   A++  VP F   +   + E+V KL  +VF PGD I ++G +G +MY +  G + ++  DG  V + LS+GSYFGEI +L       +R A VR+  +  L  L  +     + +YP  R  +E    E L++
Sbjct:    2 FFWLYIVSVAVVYNWVFIIARQCFSQLQVRFMTLWFVMDYICDIIYGMDIMVEFRTAYL---DQGLLVRDLKKLRQNYLATVKFKLDMISILPFDFLYFGL------------GTRFTLCRLLRLLRIHRVVKLFQRGETKSSYPNLLQTFA-------VVLVILLVFHWNACFYFAISESIGFGSDKWVYPNLSSNNYDKLSRQYLYSFYWS-TRMMITGESENPPETDMELLFVVADLTVGYLTFAALVGQFGAILGHIMRARVEFITHSNSIKQYMNNHKVNNDLQERVISWIDYMWHKKRSLDHERILKKLPEKLRGQIAVHVYLAVLRHVPVFADCEPGLLREIVVKLRSQVFSPGDYICRKGDVGREMYIVNSGCLQVVGDDGTTVLAILSEGSYFGEISILNLSGIGNRRTAAVRSVGFSDLLCLSKDDLLEAMSDYPEARMRLEERGRELLNR 439          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Match: ENSORLT00000019258.2 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [Source:NCBI gene;Acc:101172279])

HSP 1 Score: 587.8 bits (1514), Expect = 0.000e+0
Identity = 296/593 (49.92%), Postives = 410/593 (69.14%), Query Frame = 3
Query:  675 KDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIG-------------CNPDIITNREDFKDDLDMVKEIVSSVSPMVSXXXXXXXXXXXXXKSFNGSLKKPKESRRKSVV 2402
            +D++ + S +S+++ QF S  QP  NK +L+++GS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W+IFN  SDT FL D+ +NFRTGI++ D SD IIL+PK I   YL++WF +D ISSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L EFP++ WV   K+++  W E Y++++FKAMSHML IGYGR  P S+S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQ+I +YYEHRYQGKMF+E+ IL EL+E LRE+++N+NCR LVA++P F  A+ +FV+ +++KL +EVFQP D II+EGTIG KMYFIQ G+  +ITK G +   LSDGSYFGEICLLT  +R A+VRAE YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG              N  +  N+E+     +M++EIV     MV   +           S  G    P + +  S +
Sbjct:  323 EDAETRGSQASFMQRQFSSMLQPGVNKFSLRMYGSQKAVEREQERVKSAGNWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTTPWIIFNVVSDTFFLMDLVLNFRTGIIIEDNSD-IILDPKTIKTKYLKTWFIVDFISSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIFNLIGMMLLLCHWDGCLQFLVPMLQEFPSDCWVSLNKMENDTWSELYSFAVFKAMSHMLCIGYGRQAPESLSDIWLTMLSMIVGATCYAVFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILGELSEPLREEIVNFNCRKLVASMPLFANAEPNFVTAMLTKLRFEVFQPHDYIIREGTIGKKMYFIQHGVCSVITK-GTLAMKLSDGSYFGEICLLTRGRRTASVRAETYCRLYSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHKVQHDLNSGVFNNQEN-----EMIQEIVKYDREMVKRVDLQRPRAMSMTPSIGGIFAPPGQPQSGSAI 907          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Match: hcn4 (hyperpolarization activated cyclic nucleotide-gated potassium channel 4 [Source:ZFIN;Acc:ZDB-GENE-050420-360])

HSP 1 Score: 585.874 bits (1509), Expect = 0.000e+0
Identity = 285/517 (55.13%), Postives = 383/517 (74.08%), Query Frame = 3
Query:  702 SSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR 2240
            + ++  Q  +  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWDL ML++++ NLII+PV ++FF D     W++FN  SDT FL D+ +NFRTGI+  D + EIIL+P+ I   YLRSWF +D ISSIP+DYIFL V    +   F    + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV K K+ +  W +QY+++LFKAMSHML IGYG +PP  +++ W+TI+SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQRI +YYEHRYQGKMF+E+ IL ELNE LRE++IN+NCR LVA++P F  AD +FV+ +++KL +EVFQPGD II+EGTIG KMYFIQ G+V ++TK G   T LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++
Sbjct:  174 AGFIHRQLGAMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDEHTPPWIVFNVVSDTFFLMDLVLNFRTGIVKEDNT-EIILDPQQIKIKYLRSWFVVDFISSIPVDYIFLVVETRID-SDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPADCWVSKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILQHK 687          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Match: HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 [Source:NCBI gene;Acc:101162512])

HSP 1 Score: 580.482 bits (1495), Expect = 0.000e+0
Identity = 304/616 (49.35%), Postives = 414/616 (67.21%), Query Frame = 3
Query:  693 QSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNR--EDFKDDL------DMVKEIVSSVSPMVSXXXXXXXXXXXXXKSFNGSLKKPKESRRKSVVKLGLHKLGLIKSKSNNSLVEKKDNPNSNVITPKK 2504
            + T +Y++ QF S  QP  NK +L++FGS+ AV +E++R +    WIIHP S FRFYWD  ML+ ++ NLII+PV ++FF D     W+IFN  SDT FL D+ +NFRTGI+  D + EIIL+PK I   YL+SWF +D +SSIP+DYIFL V +G +   +  A + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV    + +  W E Y+++LFKAMSHML IGYGR  P S+S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP   RQ+I +YYEHRYQGKMF+E+ IL ELNE LRE++IN+NCR LVA++P F  AD +FV+ +++KL +EVFQPGD II+EGTIG KMYFIQ G+V I+TK G +   L DGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE YP+MRR  E+VA +RL +IG    I+ ++   D    +      +M++EIV     MV   +              G    P    R S V        L +S + N     + NP  N+ +P++
Sbjct:  213 RGTQTYMQRQFSSLLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKDETTTPWIIFNVISDTFFLMDLVLNFRTGIVFEDNT-EIILDPKKIKMKYLKSWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTA-RALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSLNNMVNDTWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIIGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIINFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSILTK-GNISMKLMDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHKVQHDLNSGVFNNHENEMIQEIVKYDREMVQQVDLSRPRAGTPPPP-AGVFTPPFAQHRDSAVAT------LQQSVAMNFCPPMQGNPVGNLQSPRR 818          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Match: hcn1 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 [Source:NCBI gene;Acc:101168057])

HSP 1 Score: 573.548 bits (1477), Expect = 0.000e+0
Identity = 282/526 (53.61%), Postives = 392/526 (74.52%), Query Frame = 3
Query:  702 SSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVY-AGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLD 2264
            S +++ QF +  QP  NK +L++FGS+ AV +E++R Q    WIIHP S FRFYWDL ML+M++ NLII+PV ++FF++     W++FN  SDT+FL D+ +NFRTGI+  ++S EIIL+PK+I  NYL+SWF +D +SSIP+DYIFL V +G  +   VY   + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+Q+L+P+L +FP + WV    + +  W +QY+++LFKAMSHML IGYG   P S+S+ WIT++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  LRQ+I +YYEHRYQGK+F+ED IL+ELN+ L+E+++N+NCR LVA +P F  AD +FV+ ++SKL +EVFQP D II+EGT+G KMYFIQ G+  +ITK  + +  L+DGSYFGEICLLT  +R A+VRA+ YC L+SL  + F  VLE YP+MRR  E+VA +RL +IG    ++  +  F+ DL+
Sbjct:   67 SGFMQRQFGAMMQPGVNKFSLRMFGSQKAVEKEQERVQTAGYWIIHPYSDFRFYWDLIMLIMMMGNLIIIPVGITFFSEQTTTTWLVFNVASDTIFLVDLVMNFRTGIV-NEESSEIILDPKVIKMNYLKSWFVVDFLSSIPVDYIFLIVEKG--FDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQYLVPLLQDFPPDCWVSLNGMVNVSWGKQYSYALFKAMSHMLCIGYGARAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADLRQKIHDYYEHRYQGKIFDEDNILSELNDPLKEEIVNFNCRKLVATMPLFANADPNFVTGMLSKLKFEVFQPYDYIIREGTVGKKMYFIQHGVASVITKFNKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLFSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSLLLQK--FQKDLN 586          
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Match: ENSORLT00000045599.1 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 [Source:NCBI gene;Acc:101158796])

HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0
Identity = 277/531 (52.17%), Postives = 387/531 (72.88%), Query Frame = 3
Query:  639 TGANNLDLNTDEKD-SQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVY-AGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFL----NIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIG 2213
            +G     +  D +D S   QST  +++ QF +  QP  NK +L++FGS  AV  E++R +    WIIHP S FRFYWDL ML++++ NLI+LPV ++FF D     W+IFN  SDT+F+ D+ +NFRTGI+  D + EI+L+P+ I +NYL+SWF +D +SSIP+DYIFL ++  ++    VY   + LRI+R  K+LS+LRLLRLSRL+RY+ QWEE      ++AS  + I  L+ +MLLL HW+ C+QFL+P+L +FP + WV K  + +  W  QY+++LFKAMSHML IGYG   P  +++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK+KQVE+YM++ KLP  +RQ+I  YYEHR+QGKMF+E+ IL EL+E L+E+++++NCR+LVA +P F  AD +FV+ V++KL +EVFQP D II+EGT+G KMYFIQ G V ++T+ G   T LSDGSYFGEICLLT  +R A+VRA+ YC LYSL  + F  VLE +P+MRR  E+VA +RL +IG
Sbjct:  162 SGFGGFGMGLDGEDYSNSNQST--FIQRQFGAMLQPGVNKFSLRMFGSHKAVAMEQERLKSAGAWIIHPYSDFRFYWDLLMLILMMGNLIVLPVGITFFRDENTASWIIFNVVSDTLFMVDLVLNFRTGIVKEDNT-EILLDPREIRQNYLKSWFLVDFVSSIPVDYIFLMMDSLDSE---VYRTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSKNLMVNDTWGVQYSYALFKAMSHMLCIGYGAQAPEGMTDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHEYYEHRFQGKMFDEENILGELSEPLKEEIVSFNCRSLVANMPLFANADPNFVTAVLTKLRFEVFQPADFIIREGTVGRKMYFIQHGRVSVLTR-GNKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDSFNEVLEEHPMMRRAFETVAVDRLDRIG 685          
BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Match: SMESG000038402.1 (SMESG000038402.1)

HSP 1 Score: 1543.1 bits (3994), Expect = 0.000e+0
Identity = 808/808 (100.00%), Postives = 808/808 (100.00%), Query Frame = 3
Query:  204 LKQMRQSKTIDIDEPTDINMSLADYRSTQSLDHSPSKHWSNTMNPCSQNLATSAHIHTKQSTGNFDDDLSSSLETCQCKLVNVKNKKMSGDKINSNLIPHNRWNQFRSRFLQLGSHNSTSKIASMTDVGFYCSNEKLTQKRLSDTTGANNLDLNTDEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSXXXXXXXXXXXXXKSFNGSLKKPKESRRKSVVKLGLHKLGLIKSKSNNSLVEKKDNPNSNVITPKKEKHLDIXXXXXXXXXXXXXXXXVRSPDGLKNTHFKISFDMA 2627
            LKQMRQSKTIDIDEPTDINMSLADYRSTQSLDHSPSKHWSNTMNPCSQNLATSAHIHTKQSTGNFDDDLSSSLETCQCKLVNVKNKKMSGDKINSNLIPHNRWNQFRSRFLQLGSHNSTSKIASMTDVGFYCSNEKLTQKRLSDTTGANNLDLNTDEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTLRILRLAKLLSMLRLLRLSRLVRYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSDDENDNAEDNGNDKSFNGSLKKPKESRRKSVVKLGLHKLGLIKSKSNNSLVEKKDNPNSNVITPKKEKHLDIEKEKAKSLSKESLNLLVRSPDGLKNTHFKISFDMA
Sbjct:    8 LKQMRQSKTIDIDEPTDINMSLADYRSTQSLDHSPSKHWSNTMNPCSQNLATSAHIHTKQSTGNFDDDLSSSLETCQCKLVNVKNKKMSGDKINSNLIPHNRWNQFRSRFLQLGSHNSTSKIASMTDVGFYCSNEKLTQKRLSDTTGANNLDLNTDEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTLRILRLAKLLSMLRLLRLSRLVRYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSDDENDNAEDNGNDKSFNGSLKKPKESRRKSVVKLGLHKLGLIKSKSNNSLVEKKDNPNSNVITPKKEKHLDIEKEKAKSLSKESLNLLVRSPDGLKNTHFKISFDMA 815          
BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Match: SMESG000038954.1 (SMESG000038954.1)

HSP 1 Score: 891.338 bits (2302), Expect = 0.000e+0
Identity = 502/835 (60.12%), Postives = 603/835 (72.22%), Query Frame = 3
Query:  204 LKQMRQSKTIDIDEPTDI--NMSLADYRSTQSLDHSPSKHWSNTMNPCSQN-------LATSAHIHTKQSTGNFDDDLSSSLETCQCKLVNVKNKKMSGDKINSNLIPHN---RWNQFRSRFLQLGSHNSTSKIA--------SMTDVGFYCSNEKLTQ--------------KRLSDTTGA-----NNLDLNTDEKDSQ------QKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRG----ENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSXXXXXX------XXXXXXXKSFNGSLK---------KPKESRRKSVVKLGLHK-LGLIKSKSN---NSLVEKKDNPNSNVITPKK 2504
            L+ M  + + +ID PT    N  L+  RS++SL+ S  +    +                T    ++  + G+ +++ SS   T    LV+ +N         +   PH    RW   +S+F + GS      +         S  D   Y  +EK                 KR  +  G         D + DE D Q       K   SSYLKEQF SFFQPSDNKLALKLFG+KNAV +E++RQQ++ K +IHPCS+FRFYWDL MLV+LI NLI+LPV +SFF D + + W++FNC SDT+F+ DIAVNFRTGI+  D +DEIIL+PKIIAR Y++SWF LDL+SSIP+DY+FL +N G    ENY  F +AG+TLRI RLAKLLSMLRLLRLSRLVRYVSQWEEFLN+ASKFIGICKLVLLMLLLGHWNAC+QFLIP+LME+P ESWV+KC L+ +YWF+QYTW+LFKAMSHMLSIGYGRFPPTSISEAWITI+SMMTGATCYALFVGHAAA+IQSFDTSKRLYREKFKQVEEYM YRKLPRALRQRIANYYEHRYQGKMF+E+ IL EL+ECLREQ+INYNCRALVAAVPFFTYADQ FVSEVV+KL +EV+QPGDLIIKEGTIGTKM+FIQEGIVDIITKDGEV TSLSDGSYFGEICLLTNAKR A+VRAE YC+LYSLD+E F+AVLENYPLMRRTMESVAAERLSKIG NP I+++RED K+DL++VKEIVSSV+P+ SDD++D            ++ S N   K         +   S+RKS ++ G+   L L KSKSN   +S V++ +  NS+    +K
Sbjct:   73 LRNMHSNLSFEIDIPTSFITNPRLSGRRSSKSLEFSSLQFAEESRQETIPESIMEQFVCPTPCKAYSAIANGDIENNGSSVASTI---LVSNRNS-------TTYRTPHKNKRRWPSIKSKFGKFGSMGKVDHLQHSVPLIHRSDHDDNNYQGSEKTAHSLSNIDSSFEKDIIKRSHEADGQFEDVDERSDESNDENDDQTNGDLNNKSRASSYLKEQFFSFFQPSDNKLALKLFGNKNAVNKERRRQQQQGKLVIHPCSNFRFYWDLMMLVLLITNLIVLPVAISFFNDDLSLHWIVFNCVSDTIFILDIAVNFRTGIITNDFADEIILDPKIIARRYVKSWFILDLLSSIPMDYLFLVLNHGPDKNENYSQFFHAGRTLRIFRLAKLLSMLRLLRLSRLVRYVSQWEEFLNMASKFIGICKLVLLMLLLGHWNACLQFLIPMLMEYPAESWVIKCNLKDAYWFKQYTWALFKAMSHMLSIGYGRFPPTSISEAWITIVSMMTGATCYALFVGHAAAIIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEEVILIELSECLREQIINYNCRALVAAVPFFTYADQDFVSEVVTKLKFEVYQPGDLIIKEGTIGTKMFFIQEGIVDIITKDGEVATSLSDGSYFGEICLLTNAKRVASVRAETYCNLYSLDAEHFQAVLENYPLMRRTMESVAAERLSKIGQNPQIVSSREDLKEDLNLVKEIVSSVTPIGSDDDDDKCNPDECENLMQSNSSMNARKKKQSSASKKCRNSFSQRKSALRQGIQNVLRLTKSKSNLSFSSAVKRSNARNSSCFVAEK 897          
BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Match: SMESG000038954.1 (SMESG000038954.1)

HSP 1 Score: 879.782 bits (2272), Expect = 0.000e+0
Identity = 503/852 (59.04%), Postives = 603/852 (70.77%), Query Frame = 3
Query:  204 LKQMRQSKTIDIDEPTDI--NMSLADYRSTQSLDHSPSKHWSNTMNPCSQN-------LATSAHIHTKQSTGNFDDDLSSSLETCQCKLVNVKNKKMSGDKINSNLIPHN---RWNQFRSRFLQLGSHNSTSKIA--------SMTDVGFYCSNEKLTQ--------------KRLSDTTGA-----NNLDLNTDEKDSQ------QKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRG----ENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEE-----------------FLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSXXXXXX------XXXXXXXKSFNGSLKKPKE---------SRRKSVVKLGLHK-LGLIKSKSN---NSLVEKKDNPNSNVITPKK 2504
            L+ M  + + +ID PT    N  L+  RS++SL+ S  +    +                T    ++  + G+ +++ SS   T    LV+ +N         +   PH    RW   +S+F + GS      +         S  D   Y  +EK                 KR  +  G         D + DE D Q       K   SSYLKEQF SFFQPSDNKLALKLFG+KNAV +E++RQQ++ K +IHPCS+FRFYWDL MLV+LI NLI+LPV +SFF D + + W++FNC SDT+F+ DIAVNFRTGI+  D +DEIIL+PKIIAR Y++SWF LDL+SSIP+DY+FL +N G    ENY  F +AG+TLRI RLAKLLSMLRLLRLSRLVRYVSQWEE                 FLN+ASKFIGICKLVLLMLLLGHWNAC+QFLIP+LME+P ESWV+KC L+ +YWF+QYTW+LFKAMSHMLSIGYGRFPPTSISEAWITI+SMMTGATCYALFVGHAAA+IQSFDTSKRLYREKFKQVEEYM YRKLPRALRQRIANYYEHRYQGKMF+E+ IL EL+ECLREQ+INYNCRALVAAVPFFTYADQ FVSEVV+KL +EV+QPGDLIIKEGTIGTKM+FIQEGIVDIITKDGEV TSLSDGSYFGEICLLTNAKR A+VRAE YC+LYSLD+E F+AVLENYPLMRRTMESVAAERLSKIG NP I+++RED K+DL++VKEIVSSV+P+ SDD++D            ++ S N   KK            S+RKS ++ G+   L L KSKSN   +S V++ +  NS+    +K
Sbjct:  136 LRNMHSNLSFEIDIPTSFITNPRLSGRRSSKSLEFSSLQFAEESRQETIPESIMEQFVCPTPCKAYSAIANGDIENNGSSVASTI---LVSNRNS-------TTYRTPHKNKRRWPSIKSKFGKFGSMGKVDHLQHSVPLIHRSDHDDNNYQGSEKTAHSLSNIDSSFEKDIIKRSHEADGQFEDVDERSDESNDENDDQTNGDLNNKSRASSYLKEQFFSFFQPSDNKLALKLFGNKNAVNKERRRQQQQGKLVIHPCSNFRFYWDLMMLVLLITNLIVLPVAISFFNDDLSLHWIVFNCVSDTIFILDIAVNFRTGIITNDFADEIILDPKIIARRYVKSWFILDLLSSIPMDYLFLVLNHGPDKNENYSQFFHAGRTLRIFRLAKLLSMLRLLRLSRLVRYVSQWEEKYLISTCDQGYLTFPQKFLNMASKFIGICKLVLLMLLLGHWNACLQFLIPMLMEYPAESWVIKCNLKDAYWFKQYTWALFKAMSHMLSIGYGRFPPTSISEAWITIVSMMTGATCYALFVGHAAAIIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEEVILIELSECLREQIINYNCRALVAAVPFFTYADQDFVSEVVTKLKFEVYQPGDLIIKEGTIGTKMFFIQEGIVDIITKDGEVATSLSDGSYFGEICLLTNAKRVASVRAETYCNLYSLDAEHFQAVLENYPLMRRTMESVAAERLSKIGQNPQIVSSREDLKEDLNLVKEIVSSVTPIGSDDDDDKCNPDECENLMQSNSSMNARKKKQSSASKKCRNSFSQRKSALRQGIQNVLRLTKSKSNLSFSSAVKRSNARNSSCFVAEK 977          
BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Match: SMESG000020049.1 (SMESG000020049.1)

HSP 1 Score: 861.677 bits (2225), Expect = 0.000e+0
Identity = 435/597 (72.86%), Postives = 512/597 (85.76%), Query Frame = 3
Query:  678 DSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSXXXXXXXXXXXXXKSFNGSLKKPKESRRKSVVKLGLHKLGLIKSKSNNSLVEKK 2468
            D   +Q+TSSYLKEQFLSFFQPSDNKLA+KLFG+KNA+ +EK+RQQ++ KW+IHPCS+FRFYWDL ML +LIANLIILPV +SFF D + ++W+IFNC SDT+FL DI VNFRTG++  D +DEIIL PK IA+NYL+SWF LD ISSIPLDYIFL +N+ E ++  ++AG+ LRILRLAKLLS+LRLLRLSRLVRYVSQWEE LN+ASKFIGI  LVLLMLLLGHWNAC+QFLIP+L ++P++SWV+KCKL+ +YWF+QYTW+LFKAMSHMLSIGYGR+PPTSI EAWITI+SMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYM YRKLPR LRQRIANYYEHRYQGKMFNE  IL EL+ECLREQ+INYNCRALVAAVPFFTYADQ+FVSEVV KL YEVFQPGDLIIKEG +GT+MYFIQEGIVDIITK+GEV TSLSDGSYFGEICLLTNA+R A+VRAE YC++YSLD + F +VLENYPLMRRTMESVAAERL KIG NP +++ R+D  +DL +VKEIV+  SP+ S           +D+SFN         RRKSV+++GL K   +++K+   + ++K
Sbjct:  244 DDANRQTTSSYLKEQFLSFFQPSDNKLAMKLFGNKNALNKEKRRQQQQGKWVIHPCSNFRFYWDLLMLSLLIANLIILPVAISFFNDDLSLKWIIFNCISDTIFLLDIFVNFRTGVITNDYADEIILVPKQIAQNYLKSWFALDFISSIPLDYIFLILNKKEYFNQIMHAGRALRILRLAKLLSLLRLLRLSRLVRYVSQWEELLNVASKFIGIFNLVLLMLLLGHWNACLQFLIPMLRDYPSDSWVIKCKLKEAYWFDQYTWALFKAMSHMLSIGYGRYPPTSICEAWITIVSMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRGLRQRIANYYEHRYQGKMFNELDILNELSECLREQIINYNCRALVAAVPFFTYADQNFVSEVVVKLQYEVFQPGDLIIKEGNLGTRMYFIQEGIVDIITKEGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNVYSLDRDSFLSVLENYPLMRRTMESVAAERLIKIGQNPLLVSTRQDLTEDLKLVKEIVNESSPISS-----------DDESFN-----EHNGRRKSVIQIGLEKFNNMRTKAAAGIAKRK 824          
BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Match: SMESG000001696.1 (SMESG000001696.1)

HSP 1 Score: 855.129 bits (2208), Expect = 0.000e+0
Identity = 434/606 (71.62%), Postives = 516/606 (85.15%), Query Frame = 3
Query:  690 KQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTXXXXXXXXXXXXXXXXXXXXXXXYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIVSSVSPMVSXXXXXXXXXXXXXKSFNGSLKKPKESRRKSVVKLGLHKLGLIKSKSNNSLV---EKKDNPNSNVITP 2498
            K ST+ YLKEQF SFFQP+DNKLA+KLFG+KNA+ +EK+RQQ+  KWIIHPCS+FRFYWDL ML++LIANLIILPV +SFF D + + W++FNC SDT+FL DI VNFR+GI+  + +DEIIL+P  I +NY+ SWFFLDLISSIP+DYIFL +NR + Y  FV+AG+ LRIL+LAKLLS+LRLLRLSRLVRYVSQWEEFLN+A+KF+GICKLVL+MLLL HWNAC+Q+LIPVL +FP +SWV KCKLQH+YWF QYTW+LFKA+SHMLSIGYGRFPPTSISEAWIT+ S++ G TCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYM YRKLPRALRQRI +YYEHRYQGKMFNED IL+EL+ECLREQ+INYNCRALVA+VPFFTYADQ FVSEVV+KL +EVFQPGDLIIKEGT+GTKMYFIQEGIVDIITKDGEV TSLSDGSYFGEICLLTNAKR A+VRAE YC+LYSLDS  F  VLENYPLMRRTMESVAAERL+KIG NP+++T+R+D K+DLD+V+E+V+S       +E++  ++         + +KP+  R+ + ++LGL  L   +S+S+ SL    E K N  +N   P
Sbjct:  196 KLSTTGYLKEQFFSFFQPADNKLAMKLFGNKNALNKEKRRQQQAGKWIIHPCSNFRFYWDLMMLILLIANLIILPVAISFFNDDLSLHWIVFNCASDTIFLLDIMVNFRSGIIADNFADEIILDPNQICKNYIHSWFFLDLISSIPMDYIFLIINRKDVYSQFVHAGRGLRILKLAKLLSILRLLRLSRLVRYVSQWEEFLNMANKFMGICKLVLMMLLLAHWNACLQYLIPVLNDFPADSWVTKCKLQHAYWFHQYTWALFKALSHMLSIGYGRFPPTSISEAWITVTSVLIGVTCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIDSYYEHRYQGKMFNEDLILSELSECLREQIINYNCRALVASVPFFTYADQDFVSEVVTKLKFEVFQPGDLIIKEGTVGTKMYFIQEGIVDIITKDGEVATSLSDGSYFGEICLLTNAKRVASVRAETYCNLYSLDSFHFLEVLENYPLMRRTMESVAAERLNKIGKNPEMVTDRKDLKEDLDLVQEMVNSAEAAAKLEESEIEDNKLLSAY---TTEKPR--RKSTAIRLGLQLLKFHRSRSHMSLSNNEENKQNAETNSQMP 796          
The following BLAST results are available for this feature:
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HCN10.000e+053.56hyperpolarization activated cyclic nucleotide gate... [more]
HCN20.000e+054.37hyperpolarization activated cyclic nucleotide gate... [more]
HCN10.000e+053.90hyperpolarization activated cyclic nucleotide gate... [more]
HCN40.000e+053.97hyperpolarization activated cyclic nucleotide gate... [more]
HCN30.000e+052.43hyperpolarization activated cyclic nucleotide gate... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-1031.956e-4026.47Potassium voltage-gated channel unc-103 [Source:U... [more]
unc-1031.250e-3925.45Potassium voltage-gated channel unc-103 [Source:U... [more]
unc-1031.385e-3926.37Potassium voltage-gated channel unc-103 [Source:U... [more]
unc-1031.807e-3926.38Potassium voltage-gated channel unc-103 [Source:U... [more]
unc-1034.252e-3926.51Potassium voltage-gated channel unc-103 [Source:U... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ih0.000e+066.28gene:FBgn0263397 transcript:FBtr0100369[more]
Ih0.000e+065.84gene:FBgn0263397 transcript:FBtr0290109[more]
Ih0.000e+065.90gene:FBgn0263397 transcript:FBtr0308835[more]
Ih0.000e+065.90gene:FBgn0263397 transcript:FBtr0290292[more]
Ih0.000e+065.90gene:FBgn0263397 transcript:FBtr0308836[more]
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BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hcn40.000e+055.32hyperpolarization activated cyclic nucleotide-gate... [more]
hcn2b0.000e+052.28hyperpolarization activated cyclic nucleotide-gate... [more]
hcn4l0.000e+055.64hyperpolarization activated cyclic nucleotide-gate... [more]
hcn10.000e+052.89hyperpolarization activated cyclic nucleotide-gate... [more]
hcn40.000e+054.02hyperpolarization activated cyclic nucleotide-gate... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lsamp0.000e+053.79limbic system associated membrane protein [Source:... [more]
lsamp0.000e+053.79limbic system associated membrane protein [Source:... [more]
lsamp0.000e+053.79limbic system associated membrane protein [Source:... [more]
lsamp0.000e+054.21limbic system associated membrane protein [Source:... [more]
lsamp0.000e+054.10limbic system associated membrane protein [Source:... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Hcn10.000e+053.56hyperpolarization activated cyclic nucleotide gate... [more]
Hcn20.000e+053.82hyperpolarization-activated, cyclic nucleotide-gat... [more]
Hcn20.000e+053.82hyperpolarization-activated, cyclic nucleotide-gat... [more]
Hcn40.000e+053.52hyperpolarization-activated, cyclic nucleotide-gat... [more]
Hcn30.000e+052.93hyperpolarization-activated, cyclic nucleotide-gat... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9JKB0|HCN1_RAT0.000e+053.56Potassium/sodium hyperpolarization-activated cycli... [more]
sp|O88704|HCN1_MOUSE0.000e+053.56Potassium/sodium hyperpolarization-activated cycli... [more]
sp|O60741|HCN1_HUMAN0.000e+053.56Potassium/sodium hyperpolarization-activated cycli... [more]
sp|Q9MZS1|HCN1_RABIT0.000e+053.56Potassium/sodium hyperpolarization-activated cycli... [more]
sp|Q9JKA9|HCN2_RAT0.000e+054.56Potassium/sodium hyperpolarization-activated cycli... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1Z1R0Y60.000e+099.45Cyclic nucleotide gated channel 1 OS=Schmidtea med... [more]
A0A267GGH40.000e+072.33Cyclic nucleotide-binding domain-containing protei... [more]
A0A267GPW90.000e+072.33Cyclic nucleotide-binding domain-containing protei... [more]
A0A4Z2DGN80.000e+079.70Potassium/sodium hyperpolarization-activated cycli... [more]
A0A4E0S1I50.000e+075.17Cyclic nucleotide and voltage-activated ion channe... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hcn4l0.000e+054.41potassium/sodium hyperpolarization-activated cycli... [more]
hcn4l0.000e+054.41potassium/sodium hyperpolarization-activated cycli... [more]
hcn2b0.000e+051.05potassium/sodium hyperpolarization-activated cycli... [more]
hcn2b0.000e+051.05potassium/sodium hyperpolarization-activated cycli... [more]
hcn10.000e+051.63potassium/sodium hyperpolarization-activated cycli... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000007865.12.226e-7447.39pep scaffold:Pmarinus_7.0:GL480431:10244:18565:-1 ... [more]
ENSPMAT00000005594.13.677e-4326.87pep scaffold:Pmarinus_7.0:GL476331:707593:738342:1... [more]
kcnh1b2.399e-3925.74potassium voltage-gated channel, subfamily H (eag-... [more]
ENSPMAT00000005922.14.140e-2723.90pep scaffold:Pmarinus_7.0:GL476456:333240:381928:-... [more]
kcnh83.710e-2423.22potassium voltage-gated channel, subfamily H (eag-... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
BCY11.056e-1135.56Regulatory subunit of the cyclic AMP-dependent pro... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO343163.675e-17452.53Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO490643.405e-16850.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO353935.123e-4226.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO353765.443e-4027.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO346331.896e-3826.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000019258.20.000e+049.92potassium/sodium hyperpolarization-activated cycli... [more]
hcn40.000e+055.13hyperpolarization activated cyclic nucleotide-gate... [more]
HCN20.000e+049.35hyperpolarization activated cyclic nucleotide gate... [more]
hcn10.000e+053.61potassium/sodium hyperpolarization-activated cycli... [more]
ENSORLT00000045599.10.000e+052.17potassium/sodium hyperpolarization-activated cycli... [more]
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BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000038402.10.000e+0100.00SMESG000038402.1[more]
SMESG000038954.10.000e+060.12SMESG000038954.1[more]
SMESG000038954.10.000e+059.04SMESG000038954.1[more]
SMESG000020049.10.000e+072.86SMESG000020049.1[more]
SMESG000001696.10.000e+071.62SMESG000001696.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007846 ID=SMED30007846|Name=Cyclic nucleotide gated channel 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2784bp
ATTTCATTGGCTCTCTTTCTACATATGGGAGCAATTAGTTAAATACAACA
AAATATTTCAATCATAAAACCAAATATTTTTTATTCACGTTAAGGATGTT
TTGAAAGAATTTCATTGAACTCAAGCTTTGATATGAAATAAAAGACTGTT
AATATAATAATCATTAGAAATACTCGTACAAAATGTCCAGCTCCAAAGTC
AAATTGAAACAGATGCGTCAGTCAAAAACCATAGACATTGATGAGCCTAC
AGATATTAACATGTCTCTGGCAGACTACCGAAGTACTCAGTCTTTAGATC
ATTCTCCATCAAAACACTGGTCAAATACTATGAATCCTTGTTCTCAAAAT
CTGGCAACATCAGCGCATATCCATACCAAGCAGTCCACTGGAAATTTTGA
CGATGACCTCTCATCATCATTGGAAACATGTCAGTGTAAATTAGTAAATG
TAAAAAACAAAAAAATGTCGGGTGATAAAATAAACTCGAATCTGATACCT
CATAATCGTTGGAATCAGTTCCGATCCAGATTTCTCCAATTGGGATCACA
CAATTCAACAAGTAAAATTGCAAGTATGACAGACGTTGGATTTTATTGCT
CGAATGAAAAACTAACGCAAAAACGACTCAGCGACACGACTGGAGCTAAT
AATTTAGACCTGAACACAGACGAAAAGGATTCTCAGCAAAAGCAGAGCAC
CTCAAGCTACCTCAAAGAACAGTTCCTTTCATTTTTTCAACCTTCTGATA
ACAAGTTAGCACTGAAATTATTCGGAAGTAAAAATGCAGTTATTCAAGAA
AAGAAAAGACAACAGAAAGAAGCAAAATGGATTATTCATCCTTGCAGTAG
CTTCAGATTTTATTGGGATCTGTTTATGTTGGTAATGCTGATCGCGAATC
TTATTATTCTGCCTGTGATAGTTTCTTTTTTTACTGACAGCATGAGGATC
CAATGGGTTATATTCAACTGTTTCTCTGATACCGTGTTCCTGGCGGACAT
CGCTGTCAATTTCAGAACAGGAATTTTGTTAACGGACAAATCAGATGAAA
TTATTCTCAATCCAAAAATTATTGCTCGTAATTACCTTAGGTCGTGGTTT
TTCCTCGACCTCATCAGTTCCATACCTCTTGATTACATATTCCTTGCCGT
GAATAGGGGCGAAAATTACCATCATTTCGTATATGCCGGAAAGACTCTTC
GAATATTACGATTAGCCAAACTGTTGAGTATGTTAAGATTATTGCGTTTA
TCAAGGCTTGTTAGATACGTCAGTCAATGGGAAGAGTTTTTGAACATAGC
CAGTAAATTTATTGGAATTTGCAAGCTGGTGCTTTTGATGCTGCTTCTTG
GACACTGGAACGCTTGTATTCAATTCCTCATTCCGGTGCTTATGGAATTC
CCGACCGAGTCTTGGGTTGTCAAATGCAAACTACAGCATTCATATTGGTT
TGAACAGTACACTTGGTCACTATTTAAAGCAATGTCTCACATGTTGAGCA
TTGGTTATGGACGGTTTCCTCCGACGAGTATTTCTGAAGCTTGGATTACT
ATAATAAGCATGATGACTGGCGCCACTTGTTATGCATTATTTGTTGGTCA
CGCTGCTGCATTAATTCAATCGTTTGACACCTCCAAGCGACTTTACAGGG
AAAAGTTCAAACAAGTGGAAGAATACATGACATATCGCAAGCTCCCGCGA
GCACTGCGTCAACGTATCGCGAACTATTACGAGCACAGATATCAGGGTAA
AATGTTCAACGAGGACCAGATTTTGACAGAATTGAATGAATGCCTGAGAG
AGCAAGTTATTAATTATAATTGTCGAGCCTTGGTAGCTGCGGTGCCATTT
TTTACATACGCAGATCAATCTTTCGTGTCAGAAGTCGTTTCTAAACTAAT
GTACGAAGTGTTTCAGCCTGGGGATTTAATTATCAAGGAAGGAACAATTG
GGACGAAAATGTATTTCATTCAGGAAGGAATCGTTGATATTATTACTAAA
GATGGAGAGGTTGTAACAAGTCTTTCGGATGGAAGTTATTTCGGAGAAAT
ATGTCTTTTAACAAACGCTAAACGATGTGCCACAGTTCGGGCCGAGGTCT
ATTGCAGTTTGTATTCTCTTGATAGTGAACAATTTAAGGCTGTGCTAGAA
AATTATCCTTTAATGCGAAGAACAATGGAAAGTGTTGCTGCTGAAAGACT
CTCTAAAATTGGGTGTAATCCAGACATCATTACAAATCGAGAAGACTTTA
AAGATGACTTAGACATGGTGAAAGAAATTGTCAGCTCAGTTAGTCCAATG
GTTAGTGATGATGAAAATGACAACGCAGAAGACAATGGAAATGATAAATC
TTTCAATGGTTCACTAAAGAAACCAAAGGAATCTCGACGAAAATCAGTTG
TCAAATTGGGTCTTCATAAATTGGGTCTCATTAAATCCAAATCCAATAAT
TCGCTAGTTGAAAAGAAAGACAATCCAAATTCTAATGTAATAACTCCGAA
AAAAGAAAAACATTTAGATATTGAAAAGGAAAAAGCAAAATCGCTTAGTA
AAGAGTCACTGAATCTTTTAGTGCGATCTCCAGACGGCCTGAAAAATACT
CATTTCAAGATCTCCTTTGATATGGCATAAGGAATGAAGATTTAATTTTG
TAATCTGTCGTCATTTTTATCTAATTTTGCTCATAGATGTGATGCTTGGT
GAATATTTGAACAATTTGTTCTTTCATGCAGCACTTGTATTTAGTTTAGA
TTAATTTATCTCTAGAAACTTTAGTGTAGTGAGA
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protein sequence of SMED30007846-orf-1

>SMED30007846-orf-1 ID=SMED30007846-orf-1|Name=SMED30007846-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=816bp
MSSSKVKLKQMRQSKTIDIDEPTDINMSLADYRSTQSLDHSPSKHWSNTM
NPCSQNLATSAHIHTKQSTGNFDDDLSSSLETCQCKLVNVKNKKMSGDKI
NSNLIPHNRWNQFRSRFLQLGSHNSTSKIASMTDVGFYCSNEKLTQKRLS
DTTGANNLDLNTDEKDSQQKQSTSSYLKEQFLSFFQPSDNKLALKLFGSK
NAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFF
TDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARN
YLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTLRILRLAKLLSM
LRLLRLSRLVRYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLI
PVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSI
SEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMT
YRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRAL
VAAVPFFTYADQSFVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGI
VDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQ
FKAVLENYPLMRRTMESVAAERLSKIGCNPDIITNREDFKDDLDMVKEIV
SSVSPMVSDDENDNAEDNGNDKSFNGSLKKPKESRRKSVVKLGLHKLGLI
KSKSNNSLVEKKDNPNSNVITPKKEKHLDIEKEKAKSLSKESLNLLVRSP
DGLKNTHFKISFDMA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000074oocyte
PLANA:0000099neuron
PLANA:0000231vitelline gland
PLANA:0000418head
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR000595cNMP-bd_dom
IPR005821Ion_trans_dom
IPR013621Ion_trans_N
IPR014710RmlC-like_jellyroll
IPR018488cNMP-bd_CS
IPR018490cNMP-bd-like
Vocabulary: biological process
TermDefinition
GO:0055085transmembrane transport
GO:0006811ion transport
GO:0006810transport
GO:0006813potassium ion transport
GO:0034220ion transmembrane transport
GO:0042391regulation of membrane potential
GO:0071805potassium ion transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0005887integral component of plasma membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0005216ion channel activity
GO:0005249voltage-gated potassium channel activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000595Cyclic nucleotide-binding domainSMARTSM00100cnmp_10coord: 556..673
e-value: 3.0E-20
score: 83.3
IPR000595Cyclic nucleotide-binding domainPFAMPF00027cNMP_bindingcoord: 576..658
e-value: 1.8E-20
score: 72.8
IPR000595Cyclic nucleotide-binding domainPROSITEPS50042CNMP_BINDING_3coord: 556..672
score: 28.412
IPR000595Cyclic nucleotide-binding domainCDDcd00038CAP_EDcoord: 556..665
e-value: 3.23186E-26
score: 101.634
NoneNo IPR availableGENE3DG3DSA:1.10.287.70coord: 227..479
e-value: 3.1E-8
score: 35.4
NoneNo IPR availableGENE3DG3DSA:1.10.287.630coord: 480..547
e-value: 8.5E-33
score: 114.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 704..736
NoneNo IPR availablePANTHERPTHR45689FAMILY NOT NAMEDcoord: 161..690
NoneNo IPR availablePANTHERPTHR45689:SF7POTASSIUM/SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 3coord: 161..690
NoneNo IPR availableSUPERFAMILYSSF81324Voltage-gated potassium channelscoord: 219..479
NoneNo IPR availableTMHMMTMhelixcoord: 455..477
NoneNo IPR availableTMHMMTMhelixcoord: 382..404
NoneNo IPR availableTMHMMTMhelixcoord: 228..250
IPR005821Ion transport domainPFAMPF00520Ion_transcoord: 226..482
e-value: 3.3E-22
score: 78.9
IPR014710RmlC-like jelly roll foldGENE3DG3DSA:2.60.120.10coord: 548..676
e-value: 6.5E-45
score: 153.9
IPR013621Ion transport N-terminalPFAMPF08412Ion_trans_Ncoord: 181..224
e-value: 5.5E-22
score: 77.1
IPR018488Cyclic nucleotide-binding, conserved sitePROSITEPS00888CNMP_BINDING_1coord: 583..599
IPR018490Cyclic nucleotide-binding-likeSUPERFAMILYSSF51206cAMP-binding domain-likecoord: 483..673