Family S60 non-peptidase homologue (S60 family)

Overview


Name	Family S60 non-peptidase homologue (S60 family)
Smed ID	SMED30007845
Length (bp)	2484

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Family S60 non-peptidase homologue (S60 family) (SMED30007845) t-SNE clustered cells

Violin plots show distribution of expression levels for Family S60 non-peptidase homologue (S60 family) (SMED30007845) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Family S60 non-peptidase homologue (S60 family) (SMED30007845) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30007845

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30007845	h1SMcG0018957	dd_Smed_v4_2523_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30007845	h1SMcG0018957	dd_Smed_v4_2523_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30007845	h1SMcG0018957	dd_Smed_v4_2523_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30007845	h1SMcG0018957	dd_Smed_v4_2523_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30007845	h1SMcG0018957	dd_Smed_v4_2523_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
Category 4 cell	SMED30007845	h1SMcG0018957	dd_Smed_v4_2523_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
epidermis	SMED30007845	h1SMcG0018957	dd_Smed_v4_4642_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

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Homology

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Human
Match: MELTF (melanotransferrin [Source:HGNC Symbol;Acc:HGNC:7037])

HSP 1 Score: 289.271 bits (739), Expect = 1.721e-85
Identity = 217/747 (29.05%), Postives = 350/747 (46.85%), Query Frame = 3

Query:  105 DIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNS--DPFAGNAGSMNCL-----DAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAM----HRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDD---TSYYAVAIAKR-ADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAG--GQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRD--EMWRLLRYSQEYFASDSNT-VFAMF-ASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            +++WC  S+ E  KC  +    R+     S     CV   S+  C+ L+  + AD + LD G  Y A + +G++    E Y+     +     Y +V VV + +  +   L G  +C  G     GW  P+  ++ES  +++  C+  +K V+ +F  GSC  G+    +      S   C  C   S     C  S  + +   +G+  CL     D A +   T      G TL +W      L+  ++LLC     DG+  + + +   C+  +  +  ++ +  +    I++  LN     F   G   S+F +F S              GQ           DL+F D+T     P  T +     +L  E+ +A+  +    +R P   ++WCV+S  E+ KC +M +A   + L+PE  CV   S  +CM  I     D +TL   ++Y  GK   LVP A E+Y  +    SYY VA+ +R +     +   + KR+CH+G G  +GW +PV   ++    R     ++ + SE    SC+P  + +P N     P +LC +C     G+++C+ +++E+YYG  GAFRC++EN GDVAF RHTTV DNT+G N   WA   RS+DYELLCP+G R +   ++ CNL +IP H ++      +P  +   ++ LL  +Q+ F  D N   F MF +S Y   DL+F D+ V   P+  +K  Y   L   +   +E +
Sbjct:   22 EVRWCATSDPEQHKCGNMSEAFREAGIQPS---LLCVRGTSADHCVQLIAAQEADAITLDGGAIYEAGKEHGLKPVVGEVYDQEVGTS-----YYAVAVVRRSSHVTIDTLKGVKSCHTGINRTVGWNVPVGYLVESGRLSVMGCDV-LKAVSDYF-GGSCVPGAGETSY------SESLCRLCRGDSSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSW--GQALLSQDFELLC----RDGSRAD-VTEWRQCHLARVPAHAVVVRADTDGGLIFR-LLNEGQRLFSHEG---SSFQMFSSEA-----------YGQK----------DLLFKDSTSEL-VPIATQTYEA--WLGHEYLHAMKGLLCDPNRLP-PYLRWCVLSTPEIQKCGDMAVAFRRQRLKPEIQCVSAKSPQHCMERIQAEQVDAVTLSGEDIYTAGKTYGLVPAAGEHYAPEDSSNSYYVVAVVRRDSSHAFTLDELRGKRSCHAGFGSPAGWDVPVGALIQRGFIRPKDCDVLTAVSEFFNASCVP--VNNPKN----YPSSLCALCVGDEQGRNKCVGNSQERYYGYRGAFRCLVENAGDVAFVRHTTVFDNTNGHNSEPWAAELRSEDYELLCPNGARAEVSQFAACNLAQIPPHAVMV-----RPDTNIFTVYGLLDKAQDLFGDDHNKNGFKMFDSSNYHGQDLLFKDATVRAVPV-GEKTTYRGWLGLDYVAALEGM 704

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Human
Match: TF (transferrin [Source:HGNC Symbol;Acc:HGNC:11740])

HSP 1 Score: 281.182 bits (718), Expect = 8.035e-83
Identity = 215/744 (28.90%), Postives = 328/744 (44.09%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR--CPFAG------IKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGD--------DTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFAS---DSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            ++WC +SE E  KC      ++     S   + +CV   S  DC+  +    AD V LD GL Y A +    ++    E Y    DP   Q FY +V VV K +      L GK +C  G G + GW  P+  +    + ++      ++     F SGSCA  +    F  L       C  C         CS  + + G +G+  CL      G    AF++  T+   LAN  +    Y+LLC     D T    +++ + C+  +  S  ++ + +  +  +  + LN    +FG +   S  F LF                      S+P    DL+F D+   F   +    ++   YL  E+  AI  +    CP A       +KWC +S  E LKC    +    K+      CV   +T +C+  I +G AD M+LD   +YI GK   LVP+  E Y          +  Y+A+A+ K++   +   N K K++CH+  G+ +GW IP+ +        +Y+      F E  +  C PG          K   +LC++C   G + C P+ +E YYG +GAFRC++E GDVAF +H TV  NT G+NP  WA+N    DYELLC DGTR     ++ C+L + P H +VT     + +   + ++LR  Q  F S   D +  F +F S     DL+F D  V L  +  D+  Y   L   + + V NL
Sbjct:   25 VRWCAVSEHEATKCQSFRDHMKSVIP-SDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDP---QTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLL----YCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQL-------CQLCPGCG-----CSTLNQYFGYSGAFKCLK----DGAGDVAFVKHSTIFENLANKADRDQ-YELLC----LDNTR-KPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDK--SKEFQLF----------------------SSPHG-KDLLFKDSAHGFL--KVPPRMDAKMYLGYEYVTAIRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEWSVNSVGKI-----ECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGK-CGLVPVLAENYNKSDNCEDTPEAGYFAIAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIPMGL--------LYNKINHCRFDEFFSEGCAPG---------SKKDSSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT----RKDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRSE--TKDLLFRDDTVCLAKL-HDRNTYEKYLGEEYVKAVGNL 681

HSP 2 Score: 178.333 bits (451), Expect = 3.065e-46
Identity = 115/355 (32.39%), Postives = 181/355 (50.99%), Query Frame = 3

Query: 1248 PFAGIKWCVISDDEMLKCRNMKLALDSKMLR--PEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYL---NLVPIAQEYYGD----DTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIA-METVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            P   ++WC +S+ E  KC++ +  + S +    P   CV   S  +C+R I+   AD +TLDA  +Y    YL   NL P+  E+YG      T YYAVA+ K+ D G  ++  + K++CH+G G+++GW IP+ +   +  + R   ++ V +F    + SC P   G  +         LC++C       C   T  QY+G SGAF+C+ +  GDVAF +H+T+ +N         A     D YELLC D TR     +  C+L ++P H +V        + D +W LL  +QE+F  D +  F +F+SP+G+ DL+F DSA     +P  + +  M L   +   + NL
Sbjct:   21 PDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDA--YLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANF---FSGSCAPCADGTDFP-------QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENL--------ANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGG--KEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGK-DLLFKDSAHGFLKVPP-RMDAKMYLGYEYVTAIRNL 345

HSP 3 Score: 73.9442 bits (180), Expect = 6.575e-13
Identity = 97/395 (24.56%), Postives = 156/395 (39.49%), Query Frame = 3

Query:   90 VENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTD-PATMQLFYTSVVVVIKGTISSPVI---LNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCL----DAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGT-LSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRC 1247
             +  + +KWC +S  E +KC        D  +++S     CV   ++ DC+  +    AD ++LD G  Y A +  G+     ENYN + +   T +  Y ++ VV K   +S +    L GK +C    G   GW  P+  +    +  I  C       + FF+ G CA GS          +S+L C  C  +  +    +N + + G  G+  CL    D A +  QT      G     W A N N    Y+LLC     DGT    + +   C+  +  +  ++T+    +       L    + FG N T  S NF LF+S                           DL+F D T+      D  +    +YL +E+  A+  + +C
Sbjct:  355 TDECKPVKWCALSHHERLKC--------DEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGK-CGLVPVLAENYNKSDNCEDTPEAGYFAIAVVKKS--ASDLTWDNLKGKKSCHTAVGRTAGWNIPMGLL----YNKINHCR-----FDEFFSEG-CAPGSKK--------DSSL-CKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPW-AKNLNEKD-YELLC----LDGTR-KPVEEYANCHLARAPNHAVVTR--KDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRSET------------------------KDLLFRDDTVCLAKLHDRNTYE--KYLGEEYVKAVGNLRKC 684

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Human
Match: LTF (lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720])

HSP 1 Score: 237.654 bits (605), Expect = 5.950e-67
Identity = 201/752 (26.73%), Postives = 319/752 (42.42%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCP------FAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTS--------------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAG--GQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYF---ASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLE 2282
            ++WC +S+ E  KC   F   R+   +      SC+   S   C+  + +  AD V LD G  Y A +  Y +R  A E Y     P T    Y +V VV KG       L G  +C  G     GW  P+  +    ++N T     ++     F S SC  G+    F  L       C  C  T +++   S+ +P+   +G+  CL      G    AF+R  T+   L++       Y+LLCP    D T    +++ + C+  +  S  ++ + V+ +     + L      FG +   S  F LF S                      P    DL+F D+ I F      +   +  YL   +  AI  + +         A + WC + + E+ KC        S +      C    +T +C+ L+  G AD M+LD   +Y  GK   LVP+  E Y    S              Y AVA+ +R+D  +  ++ K K++CH+   + +GW IP+ +        +++      F E  ++SC PG   DP +       NLC +C     G+++C+P++ E+YYG +GAFRC+ EN GDVAF +  TV  NTDG N   WA++ +  D+ LLC DG R        C+L   P H +V+       + + + ++L + Q  F    SD    F +F S     +L+F+D+   L  +   K  Y   L   +   + NL+
Sbjct:   12 VQWCAVSQPEATKC---FQWQRNMRKVRGP-PVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRT---HYYAVAVVKKGGSFQLNELQGLKSCHTGLRRTAGWNVPIGTL--RPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFPNL-------CRLCAGTGENKCAFSSQEPYFSYSGAFKCLR----DGAGDVAFIRESTVFEDLSDEAE-RDEYELLCP----DNTR-KPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDK--SPKFQLFGS----------------------PSGQKDLLFKDSAIGFSRVPPRIDSGL--YLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW-----SGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGK-CGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGL--------LFNQTGSCKFDEYFSQSCAPG--SDPRS-------NLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS----RMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARLHG-KTTYEKYLGPQYVAGITNLK 681

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Human
Match: LTF (lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720])

HSP 1 Score: 237.654 bits (605), Expect = 6.622e-67
Identity = 201/752 (26.73%), Postives = 319/752 (42.42%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCP------FAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTS--------------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAG--GQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYF---ASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLE 2282
            ++WC +S+ E  KC   F   R+   +      SC+   S   C+  + +  AD V LD G  Y A +  Y +R  A E Y     P T    Y +V VV KG       L G  +C  G     GW  P+  +    ++N T     ++     F S SC  G+    F  L       C  C  T +++   S+ +P+   +G+  CL      G    AF+R  T+   L++       Y+LLCP    D T    +++ + C+  +  S  ++ + V+ +     + L      FG +   S  F LF S                      P    DL+F D+ I F      +   +  YL   +  AI  + +         A + WC + + E+ KC        S +      C    +T +C+ L+  G AD M+LD   +Y  GK   LVP+  E Y    S              Y AVA+ +R+D  +  ++ K K++CH+   + +GW IP+ +        +++      F E  ++SC PG   DP +       NLC +C     G+++C+P++ E+YYG +GAFRC+ EN GDVAF +  TV  NTDG N   WA++ +  D+ LLC DG R        C+L   P H +V+       + + + ++L + Q  F    SD    F +F S     +L+F+D+   L  +   K  Y   L   +   + NL+
Sbjct:   25 VQWCAVSQPEATKC---FQWQRNMRKVRGP-PVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRT---HYYAVAVVKKGGSFQLNELQGLKSCHTGLRRTAGWNVPIGTL--RPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFPNL-------CRLCAGTGENKCAFSSQEPYFSYSGAFKCLR----DGAGDVAFIRESTVFEDLSDEAE-RDEYELLCP----DNTR-KPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDK--SPKFQLFGS----------------------PSGQKDLLFKDSAIGFSRVPPRIDSGL--YLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW-----SGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGK-CGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGL--------LFNQTGSCKFDEYFSQSCAPG--SDPRS-------NLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS----RMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARLHG-KTTYEKYLGPQYVAGITNLK 694

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Human
Match: LTF (lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720])

HSP 1 Score: 232.261 bits (591), Expect = 5.303e-65
Identity = 201/752 (26.73%), Postives = 318/752 (42.29%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCP------FAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTS--------------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAG--GQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYF---ASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLE 2282
            ++WC +S+ E  KC   F   R+   +      SC+   S   C+  + +  AD V LD G  Y A +  Y +R  A E Y     P T    Y +V VV KG       L G  +C  G     GW  P+  +    ++N T     ++     F S SC  G+    F  L       C  C  T +++   S+ +P+   +G+  CL      G    AF+R  T+   L++       Y+LLCP    D T    +++ + C+  +  S  ++ + V+ +     + L      FG +   S  F LF S                      P    DL+F D+ I F      +   +  YL   +  AI  + +         A + WC + + E+ KC        S +      C    +T +C+ L   G AD M+LD   +Y  GK   LVP+  E Y    S              Y AVA+ +R+D  +  ++ K K++CH+   + +GW IP+ +        +++      F E  ++SC PG   DP +       NLC +C     G+++C+P++ E+YYG +GAFRC+ EN GDVAF +  TV  NTDG N   WA++ +  D+ LLC DG R        C+L   P H +V+       + + + ++L + Q  F    SD    F +F S     +L+F+D+   L  +   K  Y   L   +   + NL+
Sbjct:   25 VQWCAVSQPEATKC---FQWQRNMRKVRGP-PVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRT---HYYAVAVVKKGGSFQLNELQGLKSCHTGLRRTAGWNVPIGTL--RPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFPNL-------CRLCAGTGENKCAFSSQEPYFSYSGAFKCLR----DGAGDVAFIRESTVFEDLSDEAE-RDEYELLCP----DNTR-KPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDK--SPKFQLFGS----------------------PSGQKDLLFKDSAIGFSRVPPRIDSGL--YLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW-----SGLSEGSVTCSSASTTEDCIAL--KGEADAMSLDGGYVYTAGK-CGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGL--------LFNQTGSCKFDEYFSQSCAPG--SDPRS-------NLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS----RMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARLHG-KTTYEKYLGPQYVAGITNLK 692

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Fly
Match: Tsf2 (gene:FBgn0036299 transcript:FBtr0075966)

HSP 1 Score: 331.257 bits (848), Expect = 1.060e-100
Identity = 240/799 (30.04%), Postives = 368/799 (46.06%), Query Frame = 3

Query:  114 WCVISESEYIKCTKLFTQI-RDFTNISSTY-NFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLF------YTSVVVVIKGTI---SSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANN--PNLA-GFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVST--RVPIYKDFLNTILNYFGP--------NGTLSSN----------FNLFQSNVVFNLSADLVLLLGQTGDTSAPQP-----------LYD--------------LMFSDATINF-YFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYG-DDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENG-DVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVT-GGFK-SQPQRDEMWRLLRYSQEYFASDSNTV--FAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPKKSGL 2312
            WC  S++E  KC  L   I RD       + N +C +  S+ +C++ +++  A I  LD G            +F    YN +  P   +        Y SV V+ KG++   ++   +  K  CF   G+  GW+ P+  +     M +  CNN+VK    +F + SCA+ S +   N +GDNS+  C+ CT      R CS++DP+ G  G+  CL       +   AFLR  T+   L      N+A   ++LLC     DG    ++N    CNWG+  +  ++T    +      Y+ FL  I   +           G  S N          +  F +N  +           +  D+S  +            LY+              L+F D++      P+D  S    +YL     N I  +  CP   +  CV S++E+ KC  M+ AL + +L+PE  C    S  NCM+ I  G AD+   DA ++Y GG   +LVP   E Y   +  YY VA+AK  D    ++  K K TCH+G   A+GW  P+ + +     R Y    V + +E   +SC+PG + + YN TG    ++C++C       C  D  E+YYG +GAFRC++E G  VAF +HTTV ++T G+    WARN  +DD+ELLC DGTR +   + +CNLGK+  + +VT GG   ++ Q +    LL Y+Q+ +         F+MF+SP G  DL+F D+   L+ IP +K+ Y   L   F R     +   G  +  L
Sbjct:   35 WCTKSQAEQYKCQNLTVAIERDRALFDEVFLNLTCFMAYSADECIHHIDREKAHITTLDAG-----------DVFTAGRYN-SLIPIMQEKLEGGFADYQSVAVIKKGSLPDLNNLRDMRNKRVCFPWVGSLAGWIVPIHTLQREGGMEVVDCNNQVKTAASYFNN-SCAVYSLSDKHNPIGDNSDKLCTLCTGKIPGGR-CSSADPYFGYEGAFKCL-----LEKGDVAFLRHSTVNEMLQTTEFKNIAPDTFELLC----RDGRRA-SINDYRQCNWGQVPADAIVTSSARSFSDRKQYQQFLKRIAELYSDGTRDDQSRQGGQSFNSRNNINDQNAYGQFDNNDPYRTQNQYDQYRSERLDSSFAEERNQQDGTNTSILYEKFRIFESKRYGKPNLLFQDSSRALTVIPEDDQSFT--KYLGPAI-NFIYGIRECPVPAMTLCVTSENELDKCIKMRTALKAHLLKPELICKKMHSHINCMQFIEAGKADISVFDAGDVYTGGLNYDLVPFMSEVYNLGEPEYYVVAVAKEDDPDTELTYLKGKNTCHTGINTAAGWTYPMALFISNGWIRPYGCDSVRAAAEYFTKSCVPGAISNEYN-TGVPYDSMCDLCHGTSYRYCRRDASEEYYGHTGAFRCLVEGGGHVAFMKHTTVMESTGGKRKEWWARNALNDDFELLCTDGTRAEIQDYKRCNLGKVKANAVVTRGGVNYNETQMNAYINLLTYAQQLYGRKEVDAFSFSMFSSPIGHYDLIFQDATRQLQVIPPNKRRYDAYLGSDFMRARRITDCYAGASQLAL 805

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Fly
Match: Tsf1 (gene:FBgn0022355 transcript:FBtr0346625)

HSP 1 Score: 91.6633 bits (226), Expect = 1.089e-18
Identity = 118/498 (23.69%), Postives = 194/498 (38.96%), Query Frame = 3

Query:  201 NFSCVLTRSSFDCMNLVNQRLADIVNL---DVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGT-ISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWM------NITTCNNEVKIVNGFFTSGSCAIG--SSNPVFNALGDN--SNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLA------NNPNLAG---FYQLLCPTAQADGTYVNALNQIEACNWG-KPQSRMLM-TQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFN-----LFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKAS 1604
               CV  R   DC+ L+ QR AD++     D+ +AY+  +N   R+ +      + D A     Y  +++V K + I +   L G  +C  G G   G+  P++K+  +  +       I+    E+K ++ FFT  SC +G  S++P  + L     +NL C+ C         C+  D F+G  G++ CLD     GQ   AF +   +  +        + P   G    ++ LC     DGT         AC+W  +P S  +   Q V     +++  L + L  F  NG  + N +     L Q N V++                           DA I+              YL +     +          I+ C  +DDE  KC+ +  A  ++  RPE  CV    +T+C+  ++   ADL T+  A  Y   +   L PI  E    D    AVA      + +  ++ K+   C      A+
Sbjct:   59 RMECVAGRDRVDCLELIEQRKADVLATEPEDMYIAYHR-KNEDYRVISEIRTQQDKDAA---FRYEGIILVKKDSPIRTLQQLRGAKSCHTGFGRNVGYKIPITKLKNTHVLKVSADPQISATERELKSLSEFFTQ-SCLVGTYSTHPETDRLLKKKYANL-CALCEKPEQ----CNYPDKFSGYDGAIRCLD----KGQGEVAFSKVQYIKKYFGLPGAGPDAPPAEGNPENFEYLC----EDGTRRPVTG--PACSWAQRPWSGYISNEQAVHNSEQLHQ--LQSRLERFFANGLQAQNKDAAAHLLIQPNAVYH-------------------------SKDAAIDPKV-----------YLERAGYKDVIERDGSAIRKIRLCAQNDDEFAKCQALHQAAYARDARPELECVQ---STDCVVALTKKEADL-TIVRATGYADARSNQLQPIVYEQRAQDDVLVAVAAPGVTREALQKASIKFNENCERSRAAAA 494

HSP 2 Score: 65.855 bits (159), Expect = 1.136e-10
Identity = 60/231 (25.97%), Postives = 97/231 (41.99%), Query Frame = 3

Query: 1353 CVMGLSTTNCMRLISDGFADLMTLDAAELYIG-----GKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGI-LISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSD-------QLVYSFSELIARSCIPGILG---DPYNPTGKNPINLCEICAAGGQDRC-LPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHD--NTDGRNPVDWARNRRSDDYELLCPDGTR 1985
            CV G    +C+ LI    AD++  +  ++YI        Y  +  I  +   D    Y   I  + D  I  +   +  ++CH+G G+  G+ IP+     T   +V +D       + + S SE   +SC+ G      +      K   NLC +C    Q  C  PD   ++ G  GA RC+ +  G+VAF++   +       G  P         +++E LC DGTR
Sbjct:   62 CVAGRDRVDCLELIEQRKADVLATEPEDMYIAYHRKNEDYRVISEIRTQQDKDAAFRYEGIILVKKDSPIRTLQQLRGAKSCHTGFGRNVGYKIPITKLKNTHVLKVSADPQISATERELKSLSEFFTQSCLVGTYSTHPETDRLLKKKYANLCALCEKPEQ--CNYPD---KFSGYDGAIRCLDKGQGEVAFSKVQYIKKYFGLPGAGPDAPPAEGNPENFEYLCEDGTR 287

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Fly
Match: Tsf1 (gene:FBgn0022355 transcript:FBtr0074559)

HSP 1 Score: 91.6633 bits (226), Expect = 1.089e-18
Identity = 118/498 (23.69%), Postives = 194/498 (38.96%), Query Frame = 3

Query:  201 NFSCVLTRSSFDCMNLVNQRLADIVNL---DVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGT-ISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWM------NITTCNNEVKIVNGFFTSGSCAIG--SSNPVFNALGDN--SNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLA------NNPNLAG---FYQLLCPTAQADGTYVNALNQIEACNWG-KPQSRMLM-TQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFN-----LFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKAS 1604
               CV  R   DC+ L+ QR AD++     D+ +AY+  +N   R+ +      + D A     Y  +++V K + I +   L G  +C  G G   G+  P++K+  +  +       I+    E+K ++ FFT  SC +G  S++P  + L     +NL C+ C         C+  D F+G  G++ CLD     GQ   AF +   +  +        + P   G    ++ LC     DGT         AC+W  +P S  +   Q V     +++  L + L  F  NG  + N +     L Q N V++                           DA I+              YL +     +          I+ C  +DDE  KC+ +  A  ++  RPE  CV    +T+C+  ++   ADL T+  A  Y   +   L PI  E    D    AVA      + +  ++ K+   C      A+
Sbjct:   59 RMECVAGRDRVDCLELIEQRKADVLATEPEDMYIAYHR-KNEDYRVISEIRTQQDKDAA---FRYEGIILVKKDSPIRTLQQLRGAKSCHTGFGRNVGYKIPITKLKNTHVLKVSADPQISATERELKSLSEFFTQ-SCLVGTYSTHPETDRLLKKKYANL-CALCEKPEQ----CNYPDKFSGYDGAIRCLD----KGQGEVAFSKVQYIKKYFGLPGAGPDAPPAEGNPENFEYLC----EDGTRRPVTG--PACSWAQRPWSGYISNEQAVHNSEQLHQ--LQSRLERFFANGLQAQNKDAAAHLLIQPNAVYH-------------------------SKDAAIDPKV-----------YLERAGYKDVIERDGSAIRKIRLCAQNDDEFAKCQALHQAAYARDARPELECVQ---STDCVVALTKKEADL-TIVRATGYADARSNQLQPIVYEQRAQDDVLVAVAAPGVTREALQKASIKFNENCERSRAAAA 494

HSP 2 Score: 65.855 bits (159), Expect = 1.136e-10
Identity = 60/231 (25.97%), Postives = 97/231 (41.99%), Query Frame = 3

Query: 1353 CVMGLSTTNCMRLISDGFADLMTLDAAELYIG-----GKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGI-LISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSD-------QLVYSFSELIARSCIPGILG---DPYNPTGKNPINLCEICAAGGQDRC-LPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHD--NTDGRNPVDWARNRRSDDYELLCPDGTR 1985
            CV G    +C+ LI    AD++  +  ++YI        Y  +  I  +   D    Y   I  + D  I  +   +  ++CH+G G+  G+ IP+     T   +V +D       + + S SE   +SC+ G      +      K   NLC +C    Q  C  PD   ++ G  GA RC+ +  G+VAF++   +       G  P         +++E LC DGTR
Sbjct:   62 CVAGRDRVDCLELIEQRKADVLATEPEDMYIAYHRKNEDYRVISEIRTQQDKDAAFRYEGIILVKKDSPIRTLQQLRGAKSCHTGFGRNVGYKIPITKLKNTHVLKVSADPQISATERELKSLSEFFTQSCLVGTYSTHPETDRLLKKKYANLCALCEKPEQ--CNYPD---KFSGYDGAIRCLDKGQGEVAFSKVQYIKKYFGLPGAGPDAPPAEGNPENFEYLCEDGTR 287

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Fly
Match: Tsf3 (gene:FBgn0034094 transcript:FBtr0087130)

HSP 1 Score: 64.3142 bits (155), Expect = 3.293e-10
Identity = 87/387 (22.48%), Postives = 144/387 (37.21%), Query Frame = 3

Query: 1158 FYFPQDTVSLNIFQYLNQE--FQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELI-ARSCIPGILGDPYNPTGKNPIN----LCEICAAGGQDRCLPDTRE------QYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLG-KIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTV---FAMFASPYGRSDLMF---SDSAVSLKPIPADKQNYTM--ILDR 2252
            F  P D V + I  YL+Q   FQ+A +     P   I +C  S  + +KC  ++ A     ++P   CV  +    C+        D++ +D        +  NLVP+  E+  D    Y                                    V IA+      V+ D    SF +L  AR+C+P   G  +    +  +N    +  + +   +D CL + +        Y GD GA RC+ E  DVAF           G    +W       D+ +LCP G      ++  C L     GH++      S  +R+E++  LR   + F     +    F ++     R++++F   +D  + L+ +  D     M  I DR
Sbjct:  335 FTVPLDNV-IAIDDYLDQATAFQSAYSFPECNPPRSIVFCTTSIIQHIKCSWLQEASQVYGVQPNIQCVRTMDEQQCLDNTKFKETDVVLVDQEMRVKAQRDYNLVPLLYEFAADMHDRY------------------------------------VTIAL------VHKDAKFESFRDLKGARACLPSFEGAAHLSVQETIVNATGKVQSLHSYFHRDSCLWNLQSGRKCPLHYQGDEGALRCLSEGADVAFLSSDVYKKYVVGNLTSNWLTPGNHKDFRVLCPYGGIEKRSNFEYCYLHWTTRGHLMTHNS--SLTRRNEIYNSLRDMDQLFGRKYKSETRPFTLYGIFDKRNNVLFRDDTDGLLGLQELHRDNAKRVMEHIYDR 676

HSP 2 Score: 51.2174 bits (121), Expect = 3.681e-6
Identity = 54/223 (24.22%), Postives = 92/223 (41.26%), Query Frame = 3

Query: 1353 CVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNL-VPIAQEYYGDDT--SYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCI---PGILGDPYNPTGKNPI-------NLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDG 1979
            CV+G+   +C+R I  G A    L + +L +  ++ ++ + +A E    ++   Y  VA+         + + +  R CH G G  + W   +    E        D  +    + IA +     P     P+ P  K          +LCE+C     D C  D  ++++G  GA  C+    G+VA+AR   V  +  G + +    N    D+  LCPDG
Sbjct:   61 CVIGVDRLDCVRRIHKGTAHFGVLTSEDL-VAARWASVEILVASELRSHESHFEYEIVAVVDNHANIHTVHDLRGARLCHPGYGLGNHWTEVLANYFEAAMVSKTCDPEMTVTEDRIASTAKYFGPSCKAGPWVPDPKQDRILKNRYPSLCEMCYE--PDSC--DQTDKHWGRRGALYCLTSGGGNVAWARLDDVRSHF-GFSGIPAQSN--PSDFSYLCPDG 275

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Zebrafish
Match: meltf (melanotransferrin [Source:ZFIN;Acc:ZDB-GENE-050309-40])

HSP 1 Score: 261.536 bits (667), Expect = 1.207e-75
Identity = 210/758 (27.70%), Postives = 347/758 (45.78%), Query Frame = 3

Query:   87 HVENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVI--LNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYC--SNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGF----------YQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGI----KWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTS---YYAVAIAKRADKGI-LISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICA--AGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASP-YGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLE 2282
            +V     I+WCVIS +E  KC  +    + F++ S      CVL  S  +C   + ++  D  +      Y   +    ++ A E+    +D   +  +    V V+K T ++  I  L GK +C  G     GW  PL  +I+S  M++  CN    + +  F + SC  G+         D+    C +C      +  C  SN + +    G+  CL    +      AF++  T++     N +  G           YQLLC     DGT  + +   E C+  +  SR ++         I+ D   +++      G   S F++F                     +SA     +L+FSD +  F    +    N  +++ + +   I     C  + I    +WCV+S  E  KC +M +A  +K L P   CV G S  +CM+ I +  AD +TLD   +Y  GK   L+P   E Y  D+    YYAVA+ +++++ I   S+ K KR+CH+G G+ +GW IP+ + +E    R  + Q+  +  E    +C+PG     +      P NLC+ C   + GQ +C+   ++ Y G  GAFRC++EN GDVAF +H+TV  NTDG N   WA N  S +++LLC   +R +   ++KCNL ++P H ++    +       ++ LL  +Q +F  +S + F MF S  Y  SDL+F DS ++L  +  +++ Y   L +S+   +  +E
Sbjct:   16 YVSGQSTIRWCVISVAEESKCKAM---AQAFSSASVRPALKCVLAASKAECAQKLTKKEVDAFSASAKDIYDIGKLASFKIAAGES---GSDGKGITYYG---VAVVKKTNAAININNLKGKKSCHTGKNRTAGWNVPLGYLIDSGMMSVMGCNIPQGVAD--FFNASCIPGAK--------DDPASLCQQCVGDRTGQFKCDPSNKELYYAYDGAFRCL----VEDAGDVAFVKHTTVSE----NTDGKGASWAQELQSKDYQLLCR----DGTR-SPVTDYEKCHLARVPSRGIV---------IHPDITTSVVYNMLTEGLQKSGFSMF---------------------SSADFGGENLLFSDTSTKFIQAGNE---NYKEWMGRYYH--ILKAMDCSQSDIPSQLQWCVLSHGEQQKCADMAVAFKNKNLIPNIQCVYGASVEDCMKKIQNKEADAITLDGGYIYTAGKSYGLIPAVGESYTGDSDGSIYYAVAVLRKSNRDIQRFSDLKGKRSCHTGYGRTAGWNIPMGLLIEKGIIRPQTCQVAQAAGEFFESACVPGADQKDF------PENLCKQCIGDSSGQFKCVKG-KDLYDGYDGAFRCLVENHGDVAFVKHSTVFQNTDGNNTDPWAVNLDSREFQLLCSQESRAEVTQFTKCNLARVPSHAVM---IRPDTNHHIIFGLLDKAQRFFGVNSASDFKMFDSKAYEGSDLIFKDSTITLIGV-GERKTYEEWLGQSYLDSLIAME 695

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Zebrafish
Match: zgc:172271 (zgc:172271 [Source:ZFIN;Acc:ZDB-GENE-080204-110])

HSP 1 Score: 242.276 bits (617), Expect = 1.723e-68
Identity = 205/766 (26.76%), Postives = 328/766 (42.82%), Query Frame = 3

Query:  102 EDIKWCVISESEYIKCTKL---FTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRR----YC--SNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR----CPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGD--DTS--------------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQD----RCLPDTREQYYGDSGAFRCMLEN------GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFAS-PYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            + ++WC +SE+E  KC +L      +     +++    SCV   S+ DC+N +    AD+V LD G  Y AV+ +G+ + A E Y    D   +     +V VV   +      L G  +C +GA    GW  PL  ++    +         + V+ FF + SC  G++    N         C  C       R    +C  S+S+PF  N G++ CL     SG    AF+    L +      +     +LLC     DG+ +  L+    CN G+     ++T++   +  I + FL      FG  G     F LF+S   F  S                    DL+F D T       +   +++ Q L  ++   +  +         + ++WC IS  E  KC    +++ S  L     CV   S ++C+  I     D ++LDA   +I GK   LVP+  EYYG+  +TS               Y VA+ +R+ K +   +   +R+CH      +GWV+PV   + T        +    +SE+  + C+PG  G           NLC++C  G ++    RC  +  E+YYG+ GA RC++ +      GDVAF  H  +  N +  N   WA    + D+ELLC DG+R     W  CNLG +P ++++T    +      ++ LL  SQ+   +  ++ F +F S  YG SDL+F D    L  +     +Y  IL   F  Q E++
Sbjct:   23 KKMRWCAVSEAEQKKCAELAKALVAVLPPAAVTAFARLSCVKAYSTADCINKIRDNKADLVTLDAGEVYSAVKQFGLTVVAKEIYR---DGGCI----LAVAVVRNNSSLDMRSLQGSRSCHSGARWTAGWSLPLGHLLSRNLLPWAEDEPISQAVSAFFNA-SCVPGATTMAANL--------CFLCKGQRSYIRQKNFHCETSHSEPFYHNQGALRCLQ----SGAGDIAFVDHTALDSIDEREKDE---LRLLC----TDGS-LAPLSSFRTCNLGRGPGGGVVTRMNIRK--IARKFLVAAQMSFGWRGRERRRFQLFES-ASFGGS--------------------DLLFRDVTEKLSVLME--DMDMSQVLGLDYVALLKGLGHEGSSLEDSVVRWCCISHAEQKKCEQWAISIKSDPL----VCVKASSMSDCIEKIKRDEVDAVSLDATHAFIAGK-CGLVPVVTEYYGEKCETSAGGGGHFESNELPPVYGVAVVRRSSKSLFFGSLADRRSCHGHMYSPAGWVLPVRHTLSTEHNNSAPCEPNKVYSEVFWKGCLPGGQG-----------NLCKVCMGGTEEAATKRCADNHNERYYGNMGALRCLVGDPTGKSFGDVAFMEHHNLESNIERLNTSGWAEGWVTWDFELLCSDGSRAPLSQWKSCNLGAVPPNIVMTRPVLTA----RIYDLLMKSQDTTEARPDSGFHLFESQQYGESDLLFKDVTKCL--VHTSHMDYRTILGNEFCSQAESI 713

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Query:  102 EDIKWCVISESEYIKCTKL---FTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRR----YC--SNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR----CPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGD--DTS--------------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQD----RCLPDTREQYYGDSGAFRCMLEN------GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFAS-PYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            + ++WC +SE+E  KC +L      +     +++    SCV   S+ DC+N +    AD+V LD G  Y AV+ +G+ + A E Y    D   +     +V VV   +      L G  +C +GA    GW  PL  ++    +         + V+ FF + SC  G++    N         C  C       R    +C  S+S+PF  N G++ CL     SG    AF+    L +      +     +LLC     DG+ +  L+    CN G+     ++T++   +  I + FL      FG  G     F LF+S   F  S                    DL+F D T       +   +++ Q L  ++   +  +         + ++WC IS  E  KC    +++ S  L     CV   S ++C+  I     D ++LDA   +I GK   LVP+  EYYG+  +TS               Y VA+ +R+ K +   +   +R+CH      +GWV+PV   + T        +    +SE+  + C+PG  G           NLC++C  G ++    RC  +  E+YYG+ GA RC++ +      GDVAF  H  +  N +  N   WA    + D+ELLC DG+R     W  CNLG +P ++++T    +      ++ LL  SQ+   +  ++ F +F S  YG SDL+F D    L  +     +Y  IL   F  Q E++
Sbjct:   23 KKMRWCAVSEAEQKKCAELAKALVAVLPPAAVTAFARLSCVKAYSTADCINKIRDNKADLVTLDAGEVYSAVKQFGLTVVAKEIYR---DGGCI----LAVAVVRNNSSLDMRSLQGSRSCHSGARWTAGWSLPLGHLLSRNLLPWAEDEPISQAVSAFFNA-SCVPGATTMAANL--------CFLCKGQRSYIRQKNFHCETSHSEPFYHNQGALRCLQ----SGAGDIAFVDHTALDSIDEREKDE---LRLLC----TDGS-LAPLSSFRTCNLGRGPGGGVVTRMNIRK--IARKFLVAAQMSFGWRGRERRRFQLFES-ASFGGS--------------------DLLFRDVTEKLSVLME--DMDMSQVLGLDYVALLKGLGHEGSSLEDSVVRWCCISHAEQKKCEQWAISIKSDPL----VCVKASSMSDCIEKIKRDEVDAVSLDATHAFIAGK-CGLVPVVTEYYGEKCETSAGGGGHFESNELPPVYGVAVVRRSSKSLFFGSLADRRSCHGHMYSPAGWVLPVRHTLSTEHNNSAPCEPNKVYSEVFWKGCLPGGQG-----------NLCKVCMGGTEEAATKRCADNHNERYYGNMGALRCLVGDPTGKSFGDVAFMEHHNLESNIERLNTSGWAEGWVTWDFELLCSDGSRAPLSQWKSCNLGAVPPNIVMTRPVLTA----RIYDLLMKSQDTTEARPDSGFHLFESQQYGESDLLFKDVTKCL--VHTSHMDYRTILGNEFCSQAESI 713

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Zebrafish
Match: tfa (transferrin-a [Source:ZFIN;Acc:ZDB-GENE-980526-35])

HSP 1 Score: 208.379 bits (529), Expect = 5.652e-57
Identity = 195/743 (26.24%), Postives = 330/743 (44.41%), Query Frame = 3

Query:  102 EDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKI---VNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMH----RCPFAGIK--WCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDT-SYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGG-----QDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPD--GTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPAD-----KQNYTMILDRSF 2258
            + +KWCV +++E  KC  L T+  D           C L  +  DCM  +     DIV +D    +   + NY +R    E           +  Y +V  V  G+  +   L GKS+C +    + GW  P+ K+I +  +      NE+ +   V+ FF+S SC  G S P +  L       CS           CS+++ + G+ G+  CL     +GQ   AF+    +      N      Y+LLC     DG+   ++   + CN+ +  +R ++ +  +    +Y D L  I     P   L S+      +++F+ SA  ++LL                          P+ T SL    YL +E+  A+ A        P +  K   C I   E  KC ++     S        C++  S  +C+  I    AD + +D  ++YI GK   LVP+  E     T SYYAVA+ ++   G+  +N + K++CH+G G+++GW IP        +  +  ++   +  +  +  C PG   DP +       N+C++C   G     + +C P   EQYYG  GAFRC+ E  GDVAF +HT V D TDG+   DWA++ +S+D+EL+CP+   T +    + KCNL ++P H ++T       + D    ++ +  +  + +++    +F S  G+ +L+F+D    L+ I         + Y  +++R++
Sbjct:   23 KKVKWCVTTQNEQSKCRHLATKAADI---------ECHLQPTVIDCMRSIAAGGTDIVTVDGANVFTGGLNNYLLRPIIAEKKK--------ECCY-AVAAVKAGSGFNINELKGKSSCHSCYQRSGGWNTPIGKLIATNKITWEG-PNEMPVERAVSEFFSS-SCVPGVSKPKYPNLCKACQGDCS-----------CSHNEKYFGDDGAFQCL--KNDNGQV--AFVCHHAIPESERQN------YELLC----MDGSR-KSVEDYKTCNFAREPARTVIARTDTDLQYVY-DVLKQI-----PASDLFSSQAFGGKDLIFSDSATELMLL--------------------------PKRTDSL---LYLKEEYYEAMQAFKDGNPSAPTSQTKLAMCTIGHAEKNKCDSLDHVKKS--------CILEASVDDCIEKIKRKEADFLAVDGGQVYIAGK-CGLVPVMAEQSNSRTASYYAVAVVRKGS-GLTWNNLEGKKSCHTGLGRSAGWKIP--------ESAICGEKDKCTLDKFFSEGCAPG--ADPTS-------NMCKLCKGSGKPVGDESKCKPSAEEQYYGYDGAFRCLAEKAGDVAFIKHTVVGDYTDGKGK-DWAKDLKSEDFELICPNTPDTTMKYTDFEKCNLAQVPVHAVIT-------REDARSAVVSFLSDIQSKNND----LFTSKDGK-NLLFTDGTKCLQEIKGSVDDFLTKKYIDMIERTY 644

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Zebrafish
Match: otomp (otolith matrix protein [Source:NCBI gene;Acc:565818])

HSP 1 Score: 195.282 bits (495), Expect = 5.789e-55
Identity = 116/351 (33.05%), Postives = 182/351 (51.85%), Query Frame = 3

Query: 1260 IKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNL-VPIAQEYYG-DDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRV-YSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDR--CLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASP-YGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIG 2291
            I+WC +SD E  KC ++     ++ LR +  CV G S T+CM+ I +G AD  T+ A E+Y  G    L V + + Y G D  +YY VA+A+ +   + +     + +CH G     GW +P+   + T Q  V       ++  +    SC+PG+    ++P G NP NLCE C     DR  C  + RE+++G++GA RC+ EN GDVAF +HTTV DN  G+N   WA +   +D +LLCPDG+  + +    C+L  +P + +V         +  +++ L   Q  F + +   F++F+S  YG+ D++FSDS   L  +      YT  L  S+   +   E  G
Sbjct:   27 IRWCTVSDAEDQKCLDLAGNATARNLRGQLVCVRGQSPTDCMKQIKNGTADASTMYADEIYTAGFCYGLDVAVGESYNGVDGINYYVVALARTSSSDLSLLEMHERSSCHPGMRTTVGWTVPIGFLVNTSQISVDVQCNFPHAVGDFFGYSCVPGVKDPEHDPKGNNPRNLCEACIGDENDRHICANNPRERHFGEAGALRCVAENLGDVAFVKHTTVFDNMQGKNQESWALDLELEDLKLLCPDGSEANLFQHESCHLAVVPTNAVVV----RLEDKCRVYKFLERVQNAFGNTTEG-FSLFSSVNYGQPDVLFSDSTKKLLRVMG---TYTSWLGPSYTTILRAFECEG 369

HSP 2 Score: 78.5666 bits (192), Expect = 4.896e-15
Identity = 85/335 (25.37%), Postives = 144/335 (42.99%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNS--DPFAGNAGSMNCL-----DAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFG---PNGTLSSNFNLFQSNVVFNLSADLVL 1082
            I+WC +S++E  KC  L     + T  +      CV  +S  DCM  +    AD   +     Y A   YG+ +   E+YN   D      +Y   +     +  S + ++ +S+C  G  T  GW  P+  ++ +  +++    N    V  FF   SC  G  +P  +  G+N    C  C    + R  C+N+  +   G AG++ C+     D A +   T    ++G    +W  +        +LLCP    DG+  N L Q E+C+     +  ++ +L   +  +YK FL  + N FG      +L S+ N  Q +V+F+ S   +L
Sbjct:   27 IRWCTVSDAEDQKCLDL---AGNATARNLRGQLVCVRGQSPTDCMKQIKNGTADASTMYADEIYTAGFCYGLDVAVGESYN-GVDGIN---YYVVALARTSSSDLSLLEMHERSSCHPGMRTTVGWTVPIGFLVNTSQISVDVQCNFPHAVGDFFGY-SCVPGVKDPEHDPKGNNPRNLCEACIGDENDRHICANNPRERHFGEAGALRCVAENLGDVAFVKHTTVFDNMQGKNQESWALDLELED--LKLLCP----DGSEAN-LFQHESCHLAVVPTNAVVVRL-EDKCRVYK-FLERVQNAFGNTTEGFSLFSSVNYGQPDVLFSDSTKKLL 344

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Xenopus
Match: MELTF (melanotransferrin [Source:NCBI gene;Acc:100158653])

HSP 1 Score: 295.049 bits (754), Expect = 5.413e-88
Identity = 216/749 (28.84%), Postives = 350/749 (46.73%), Query Frame = 3

Query:   99 VEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLT-NWLANNPN------LAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFA---GIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGD---DTSYYAVAIAKRAD-KGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKN-PINLCEICA--AGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRD--EMWRLLRYSQEYFASDSNTVFAMF-ASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLE 2282
            + +++WC IS+ E  KC  +      F     T   SCV  +S  DC  ++    AD V L+  L Y A   Y ++  A E Y+       M   Y +V VV K +  +   L G  +C  G     GW  P+  +I+S  + +  CN + K V+ FF S SC  GS+              C  C   ++    C  +  ++  +G+  CL    + GQ   AF++  T+  N    N +      ++  YQLLC     DG++ + +++   CN  +  +  +MT+  +    IYK   +    Y       SS F +F S+  +N +                    +L+F D T      + T +     +L  ++  A+  ++  P      ++WC +S  E+ KC +M      K L P   CV   S   CM LI     D +TLD  ++Y  GK   LVP A E Y +    +SYYAVA+ +R       I + K K++CH+G  + +GW +P+   ++    R        + +   + SC+PG          KN P  LC++C   + GQ++C  DTREQY+G SGAFRC+ E  GDVAF +H TV + TDG++   WA+N +S D++LLCP+G R +   +  CN  ++P H ++       P  +   ++ LL  +QEY+ +D+++ F MF +S Y  +DL+F DS   + P+  +K+ Y+  L   +   +E ++
Sbjct:   12 LNEVRWCTISDPENKKCNDMKAA---FGQAKITPMLSCVNGKSGMDCARMIMNNEADAVTLNGELIYQAGSQYNLKPVAGEVYD-----QGMGTSYYAVAVVRKNSSYTINNLKGAKSCHTGFQRTAGWNVPIGYLIDSGRIAVVACNIQ-KAVSSFF-SQSCVPGSTQADL----------CQLCIGDANGTNVCDLNGRYSDYSGAFRCL----VEGQGDVAFIKHSTVAENSDGKNTDSWAREVISSDYQLLC----RDGSHAD-ISEWRQCNLARVPAHAVMTRTNTDGSLIYKMLQDGQQKY----NIHSSGFRMFDSSA-YNSN--------------------NLLFRDMTTEL---RATGNQTYQAWLGDDYLQAMKGINCDPDKLPKSLRWCTLSTPEIWKCADMARVFKDKNLDPSLQCVSADSPEACMELIRQKEVDAVTLDGGDVYKAGKTYGLVPAAGESYPETNLSSSYYAVALVRRDPLNAFTIHDLKGKKSCHTGYERTAGWNVPIGALIKLGSIRPDECNTAKAVANFFSGSCVPG-------ANQKNFPPELCKLCKGDSKGQNKCEKDTREQYFGYSGAFRCLAEKAGDVAFVKHATVFELTDGQSTESWAKNLKSSDFQLLCPNGARAEVSQYPDCNWAQVPAHAVMV-----HPDTNIHAVYGLLANAQEYYGNDNSSQFKMFDSSSYNANDLIFKDSTYKIVPV-QEKKTYSQWLGSGYLESLEGMQ 690

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Xenopus
Match: tf (transferrin [Source:NCBI gene;Acc:613079])

HSP 1 Score: 268.855 bits (686), Expect = 2.021e-78
Identity = 215/760 (28.29%), Postives = 338/760 (44.47%), Query Frame = 3

Query:  102 EDIKWCVISESEYIKCTKLFTQIRDFTNI--SSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYY-AVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEV--KIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNT--ILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAG--IKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTS------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAG------GQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMW-RLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPKKSGLF 2315
            + ++WC  S+SE+ KC       RD  N   +     SCV   S+ +C+  +    AD + +D G  Y  ++Q Y ++    ENY  +T+P T    Y +V VV K +  +   L  K +C  G G   GW   +  ++E + +     + E   K V+ FF + SC  G+  P            C +C    + +   SN++P+   AG+  CL       +   AF++  T+   L  +      Y+LLCP    D T    ++  + CN  K  +  ++ +    +      FL    +L +  P  +   N++  +   +F                 + Q   DL+F D  ++      T+  + F +L   +   I A+      G  ++WC  S  E  KC +      + +      C    +  +C+  I  G AD +TLD   +Y  G+   LVP+  EYY    S      YYAVAIAK+  K +   N +  +TCH+  G+ +GW IPV +        + ++     F   +  SC PG              NLC++C            +C P   E Y+G SGAFRC++E GDV FA+HTTV +NTDG+NP  WA++ +SDDYELLCPDG+R     + +CNL ++P H +VT   K +P  + +  +   Y ++ F  D   +F MF S  G+ DL+F DS   L  I ++K      L   +   V +L       KSGL 
Sbjct:   14 KQVRWCAKSKSEFSKC-------RDLVNTCKNKEITLSCVEKSSTDECLTAIQNDRADAICVDGGDVYKGSLQPYNLKPIMAENYGSHTEPDTC---YYAVAVVKKSSTFTFDELRDKRSCHTGIGKTAGWNVIIGLLLEKQLLKWEGPDTESLEKAVSKFFKA-SCVPGAKEPKL----------CQQCAGKKEHKCARSNNEPYYNYAGAFKCLQ----DDKGDVAFVKHSTVPEELHKD------YELLCP----DNTR-KPISDYKNCNLAKVPAHSVLARARDDKSKDIIAFLQEAQVLPFSIPCTSADENWHKTKECKLF-----------------SSQHGKDLLFKDTAVSLVPLPPTI--DGFLFLGAVYYQEIHALKEGVKEGNKVRWCTQSKAEKTKCDDW-----TTISGGSIECTEAATAEDCILQILKGDADAVTLDGGYMYTAGQ-CGLVPVMGEYYDLGKSSQAKGVYYAVAIAKKGTK-VSWKNLRGVKTCHTAVGRTAGWNIPVGL--------ITNETNNCDFGNYVGESCAPG---------SDVKSNLCKLCIGDPAKPLDSAKKCSPSASEAYHGYSGAFRCLVEKGDVCFAKHTTVFENTDGKNPAAWAKDLKSDDYELLCPDGSRAPINDFKRCNLAEVPAHSVVTLPGKRKPVVEILVNQQSLYGRKGFQKD---IFQMFQSKDGK-DLLFKDSTQCLLEI-SEKTTMQEFLGDKYYTAVTSLNKCSNT-KSGLL 688

HSP 2 Score: 72.0182 bits (175), Expect = 3.072e-12
Identity = 95/399 (23.81%), Postives = 157/399 (39.35%), Query Frame = 3

Query:   90 VENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVN-GFFTSGSCAIGS---SNPVFNALGDNSNLACSKCTNTSDSRRYC--SNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTL-TNWLANNPNL------AGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRC 1247
            V+    ++WC  S++E  KC        D+T IS   +  C    ++ DC+  + +  AD V LD G  Y A Q  G+     E Y+         ++Y +V +  KGT  S   L G   C    G   GW  P+  +            NE    + G +   SCA GS   SN     +GD +           DS + C  S S+ + G +G+  C     L  +    F +  T+  N    NP        +  Y+LLCP    DG+    +N  + CN  +  +  ++T L   R P+ +  +N   + +G  G     F +FQS                       +   DL+F D+T       +  ++   ++L  ++  A+T++++C
Sbjct:  348 VKEGNKVRWCTQSKAEKTKCD-------DWTTISGG-SIECTEAATAEDCILQILKGDADAVTLDGGYMYTAGQ-CGLVPVMGEYYDLGKSSQAKGVYY-AVAIAKKGTKVSWKNLRGVKTCHTAVGRTAGWNIPVGLI-----------TNETNNCDFGNYVGESCAPGSDVKSNLCKLCIGDPA--------KPLDSAKKCSPSASEAYHGYSGAFRC-----LVEKGDVCFAKHTTVFENTDGKNPAAWAKDLKSDDYELLCP----DGSRA-PINDFKRCNLAEVPAHSVVT-LPGKRKPVVEILVNQ-QSLYGRKGFQKDIFQMFQS-----------------------KDGKDLLFKDSTQCLLEISEKTTMQ--EFLGDKYYTAVTSLNKC 680

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Xenopus
Match: tf (transferrin [Source:NCBI gene;Acc:613079])

HSP 1 Score: 267.7 bits (683), Expect = 4.605e-78
Identity = 215/755 (28.48%), Postives = 332/755 (43.97%), Query Frame = 3

Query:  102 EDIKWCVISESEYIKCTKLFTQIRDFTNI--SSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYY-AVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEV--KIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTS-----APQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAG------GQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMW-RLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPKKSGLF 2315
            + ++WC  S+SE+ KC       RD  N   +     SCV   S+ +C+  +    AD + +D G  Y  ++Q Y ++    ENY  +T+P T    Y +V VV K +  +   L  K +C  G G   GW   +  ++E + +     + E   K V+ FF + SC  G+  P            C +C    + +   SN++P+   AG+  CL       +   AF++  T+   L  +      Y+LLCP                                 +TR PI  D+ N  L     +  L+   +        + S D++  L +   T      + Q   DL+F D  ++      T+  + F +L   +   I A+       ++WC  S  E  KC +      + +      C    +  +C+  I  G AD +TLD   +Y  G+   LVP+  EYY D   YYAVAIAK+  K +   N +  +TCH+  G+ +GW IPV +        + ++     F   +  SC PG              NLC++C            +C P   E Y+G SGAFRC++E GDV FA+HTTV +NTDG+NP  WA++ +SDDYELLCPDG+R     + +CNL ++P H +VT   K +P  + +  +   Y ++ F  D   +F MF S  G+ DL+F DS   L  I ++K      L   +   V +L       KSGL 
Sbjct:   20 KQVRWCAKSKSEFSKC-------RDLVNTCKNKEITLSCVEKSSTDECLTAIQNDRADAICVDGGDVYKGSLQPYNLKPIMAENYGSHTEPDTC---YYAVAVVKKSSTFTFDELRDKRSCHTGIGKTAGWNVIIGLLLEKQLLKWEGPDTESLEKAVSKFFKA-SCVPGAKEPKL----------CQQCAGKKEHKCARSNNEPYYNYAGAFKCLQ----DDKGDVAFVKHSTVPEELHKD------YELLCPD--------------------------------NTRKPI-SDYKNCNLAKVPAHSVLARARD--------DKSKDIIAFLQEAQKTKECKLFSSQHGKDLLFKDTAVSLVPLPPTI--DGFLFLGAVYYQEIHALKE-GVKEVRWCTQSKAEKTKCDDW-----TTISGGSIECTEAATAEDCILQILKGDADAVTLDGGYMYTAGQ-CGLVPVMGEYY-DLGVYYAVAIAKKGTK-VSWKNLRGVKTCHTAVGRTAGWNIPVGL--------ITNETNNCDFGNYVGESCAPG---------SDVKSNLCKLCIGDPAKPLDSAKKCSPSASEAYHGYSGAFRCLVEKGDVCFAKHTTVFENTDGKNPAAWAKDLKSDDYELLCPDGSRAPINDFKRCNLAEVPAHSVVTLPGKRKPVVEILVNQQSLYGRKGFQKD---IFQMFQSKDGK-DLLFKDSTQCLLEI-SEKTTMQEFLGDKYYTAVTSLNKCSN-TKSGLL 668

HSP 2 Score: 72.7886 bits (177), Expect = 1.362e-12
Identity = 96/398 (24.12%), Postives = 157/398 (39.45%), Query Frame = 3

Query:   93 ENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVN-GFFTSGSCAIGS---SNPVFNALGDNSNLACSKCTNTSDSRRYC--SNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTL-TNWLANNPNL------AGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRC 1247
            E V++++WC  S++E  KC        D+T IS   +  C    ++ DC+  + +  AD V LD G  Y A Q  G+     E Y+           Y +V +  KGT  S   L G   C    G   GW  P+  +            NE    + G +   SCA GS   SN     +GD +           DS + C  S S+ + G +G+  C     L  +    F +  T+  N    NP        +  Y+LLCP    DG+    +N  + CN  +  +  ++T L   R P+ +  +N   + +G  G     F +FQS                       +   DL+F D+T       +  ++   ++L  ++  A+T++++C
Sbjct:  336 EGVKEVRWCTQSKAEKTKCD-------DWTTISGG-SIECTEAATAEDCILQILKGDADAVTLDGGYMYTAGQ-CGLVPVMGEYYDLGV--------YYAVAIAKKGTKVSWKNLRGVKTCHTAVGRTAGWNIPVGLI-----------TNETNNCDFGNYVGESCAPGSDVKSNLCKLCIGDPA--------KPLDSAKKCSPSASEAYHGYSGAFRC-----LVEKGDVCFAKHTTVFENTDGKNPAAWAKDLKSDDYELLCP----DGSRA-PINDFKRCNLAEVPAHSVVT-LPGKRKPVVEILVNQ-QSLYGRKGFQKDIFQMFQS-----------------------KDGKDLLFKDSTQCLLEISEKTTMQ--EFLGDKYYTAVTSLNKC 660

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Xenopus
Match: tf (transferrin [Source:NCBI gene;Acc:613079])

HSP 1 Score: 261.536 bits (667), Expect = 1.178e-75
Identity = 214/772 (27.72%), Postives = 334/772 (43.26%), Query Frame = 3

Query:  102 EDIKWCVISESEYIKCTKLFTQIRDFTNI--SSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYY-AVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEV--KIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTS-----APQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR-------CPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTS----------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAG------GQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMW-RLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPKKSGLF 2315
            + ++WC  S+SE+ KC       RD  N   +     SCV   S+ +C+  +    AD + +D G  Y  ++Q Y ++    ENY  +T+P T    Y +V VV K +  +   L  K +C  G G   GW   +  ++E + +     + E   K V+ FF + SC  G+  P            C +C    + +   SN++P+   AG+  CL       +   AF++  T+   L  +      Y+LLCP                                 +TR PI  D+ N  L     +  L+   +        + S D++  L +   T      + Q   DL+F D  ++      T+  + F +L   +   I A+            + ++WC  S  E  KC +      + +      C    +  +C+  I  G AD +TLD   +Y  G+   LVP+  EYY  +            YYAVAIAK+  K +   N +  +TCH+  G+ +GW IPV +        + ++     F+  +  SC PG              NLC++C            +C P   E Y+G SGAFRC++E GDV FA+HTTV +NTDG+NP  WA++ +SDDYELLCPDG+R     + +CNL ++P H +VT   K +P  + +  +   Y ++ F  D   +F MF S  G+ DL+F DS   L  I ++K      L   +   V +L       KSGL 
Sbjct:   21 KQVRWCAKSKSEFSKC-------RDLVNTCKNKEITLSCVEKSSTDECLTAIQNDRADAICVDGGDVYKGSLQPYNLKPIMAENYGSHTEPDTC---YYAVAVVKKSSTFTFDELRDKRSCHTGIGKTAGWNVIIGLLLEKQLLKWEGPDTESLEKAVSKFFKA-SCVPGAKEPKL----------CQQCAGKKEHKCARSNNEPYYNYAGAFKCLQ----DDKGDVAFVKHSTVPEELHKD------YELLCPD--------------------------------NTRKPI-SDYKNCNLAKVPAHSVLARARD--------DKSKDIIAFLQEAQKTKECKLFSSQHGKDLLFKDTAVSLVPLPPTI--DGFLFLGAVYYQEIHALKEGVKEDDLAAPSKVRWCTQSKAEKTKCDDW-----TTISGGSIECTEAATAEDCILQILKGDADAVTLDGGYMYTAGQ-CGLVPVMGEYYDLEAQTAPTGPVNSVYYAVAIAKKGTK-VSWKNLRGVKTCHTAVGRTAGWNIPVGL--------ITNETNNCDFASYVGESCAPG---------SDVKSNLCKLCIGDPAKPLDSAKKCSPSASEAYHGYSGAFRCLVEKGDVCFAKHTTVFENTDGKNPAAWAKDLKSDDYELLCPDGSRAPINDFKRCNLAEVPAHSVVTLPGKRKPVVEILVNQQSLYGRKGFQKD---IFQMFQSKDGK-DLLFKDSTQCLLEI-SEKTTMQEFLGDKYYTAVTSLNKCSN-TKSGLL 688

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Xenopus
Match: tf (transferrin [Source:NCBI gene;Acc:613079])

HSP 1 Score: 261.536 bits (667), Expect = 1.198e-75
Identity = 208/741 (28.07%), Postives = 324/741 (43.72%), Query Frame = 3

Query:  102 EDIKWCVISESEYIKCTKLFTQIRDFTNI--SSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYY-AVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEV--KIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTS-----APQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR-------CPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYG-DDTS------------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAG------GQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMW-RLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPI 2213
            + ++WC  S+SE+ KC       RD  N   +     SCV   S+ +C+  +    AD + +D G  Y  ++Q Y ++    ENY  +T+P T    Y +V VV K +  +   L  K +C  G G   GW   +  ++E + +     + E   K V+ FF + SC  G+  P            C +C    + +   SN++P+   AG+  CL       +   AF++  T+   L  +      Y+LLCP                                 +TR PI  D+ N  L     +  L+   +        + S D++  L +   T      + Q   DL+F D  ++      T+  + F +L   +   I A+            + ++WC  S  E  KC +      + +      C    +  +C+  I  G AD +TLD   +Y  G+   LVP+  EYY  DD +            YYAVAIAK+  K +   N +  +TCH+  G+ +GW IPV +        + ++     F+  +  SC PG              NLC++C            +C P   E Y+G SGAFRC++E GDV FA+HTTV +NTDG+NP  WA++ +SDDYELLCPDG+R     + +CNL ++P H +VT   K +P  + +  +   Y ++ F  D   +F MF S  G+ DL+F DS   L  I
Sbjct:   20 KQVRWCAKSKSEFSKC-------RDLVNTCKNKEITLSCVEKSSTDECLTAIQNDRADAICVDGGDVYKGSLQPYNLKPIMAENYGSHTEPDTC---YYAVAVVKKSSTFTFDELRDKRSCHTGIGKTAGWNVIIGLLLEKQLLKWEGPDTESLEKAVSKFFKA-SCVPGAKEPKL----------CQQCAGKKEHKCARSNNEPYYNYAGAFKCLQ----DDKGDVAFVKHSTVPEELHKD------YELLCPD--------------------------------NTRKPI-SDYKNCNLAKVPAHSVLARARD--------DKSKDIIAFLQEAQKTKECKLFSSQHGKDLLFKDTAVSLVPLPPTI--DGFLFLGAVYYQEIHALKEGVKEDDLAAPSKVRWCTQSKAEKTKCDDW-----TTISGGSIECTEAATAEDCILQILKGDADAVTLDGGYMYTAGQ-CGLVPVMGEYYDLDDLTPCQRRSSQAKGVYYAVAIAKKGTK-VSWKNLRGVKTCHTAVGRTAGWNIPVGL--------ITNETNNCDFASYVGESCAPG---------SDVKSNLCKLCIGDPAKPLDSAKKCSPSASEAYHGYSGAFRCLVEKGDVCFAKHTTVFENTDGKNPAAWAKDLKSDDYELLCPDGSRAPINDFKRCNLAEVPAHSVVTLPGKRKPVVEILVNQQSLYGRKGFQKD---IFQMFQSKDGK-DLLFKDSTQCLLEI 658

HSP 2 Score: 165.236 bits (417), Expect = 5.963e-42
Identity = 104/328 (31.71%), Postives = 164/328 (50.00%), Query Frame = 3

Query: 1260 IKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGG-KYLNLVPIAQEYYGD----DTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVY---SDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIP 2216
            ++WC  S  E  KCR++     +K +     CV   ST  C+  I +  AD + +D  ++Y G  +  NL PI  E YG     DT YYAVA+ K++         + KR+CH+G GK +GW + + + +E    +     ++ L  + S+    SC+PG          K P  LC+ CA   + +C     E YY  +GAF+C+ ++ GDVAF +H+TV +                 DYELLCPD TR     +  CNL K+P H ++     ++ + D+   ++ + QE   +       +F+S +G+ DL+F D+AVSL P+P
Sbjct:   22 VRWCAKSKSEFSKCRDLVNTCKNKEIT--LSCVEKSSTDECLTAIQNDRADAICVDGGDVYKGSLQPYNLKPIMAENYGSHTEPDTCYYAVAVVKKSST-FTFDELRDKRSCHTGIGKTAGWNVIIGLLLEKQLLKWEGPDTESLEKAVSKFFKASCVPG---------AKEP-KLCQQCAGKKEHKCARSNNEPYYNYAGAFKCLQDDKGDVAFVKHSTVPEEL-------------HKDYELLCPDNTRKPISDYKNCNLAKVPAHSVL-----ARARDDKSKDIIAFLQE---AQKTKECKLFSSQHGK-DLLFKDTAVSLVPLP 314

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Mouse
Match: Meltf (melanotransferrin [Source:MGI Symbol;Acc:MGI:1353421])

HSP 1 Score: 280.796 bits (717), Expect = 1.550e-82
Identity = 211/754 (27.98%), Postives = 346/754 (45.89%), Query Frame = 3

Query:   99 VEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNS--DPFAGNAGSMNCL-----DAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTL-----SSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAM----HRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDD---TSYYAVAIAKR-ADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAA--GGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRD--EMWRLLRYSQEYFASDSNT-VFAMF-ASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            V +++WC IS++E  KC  +      F       +  CV   S+  C+ L+ ++ AD + LD G  Y A + +G++    E Y+ +   +     Y +V VV + +  +   L G  +C  G     GW  P+  ++ES  +++  C+  +K V  +F  GSC  G+          +S   C  C   S     C  S  + +   +G+  CL     D A +   T      G+TL +W      ++  +QLLC     DG+      + +   W +     +    V  R  +    +  +LN     G L      S+F +F S                           +L+F D+T+         + N   +L QE+  A+  +    +R P   ++WCV+S  E+ KC +M +A   + L+PE  CV   S  +CM  I  G  D +TL   ++Y  GK   LVP A E Y ++    SY+ VA+A+R +     +   + KR+CH   G  +GW +P+   ++    R     ++ + S+    SC+P  + +P N     P  LC +C     G+++C+  ++E+YYG SGAFRC++E+ GDVAF +HTTV +NT+G NP  WA + R  DYELLCP+G R +   +  CNL ++P H ++      +P  +   ++ LL  +Q+ F  D N   F MF +S Y   DL+F D+ V   P+  +K  Y   L   +   +E +
Sbjct:   20 VMEVQWCTISDAEQQKCKDMSEA---FQGAGIRPSLLCVQGNSADHCVQLIKEQKADAITLDGGAIYEAGKEHGLKPVVGEVYDQDIGTS-----YYAVAVVRRNSNVTINTLKGVKSCHTGINRTVGWNVPVGYLVESGHLSVMGCD-VLKAVGDYF-GGSCVPGTGET------SHSESLCRLCRGDSSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGNTLPSW--GKSLMSEDFQLLC----RDGS------RADITEWRRCHLAKVPAHAVVVRGDMDGGLIFQLLN----EGQLLFSHEDSSFQMFSSKAYSQ---------------------KNLLFKDSTLELV---PIATQNYEAWLGQEYLQAMKGLLCDPNRLPHY-LRWCVLSAPEIQKCGDMAVAFSRQNLKPEIQCVSAESPEHCMEQIQAGHTDAVTLRGEDIYRAGKVYGLVPAAGELYAEEDRSNSYFVVAVARRDSSYSFTLDELRGKRSCHPYLGSPAGWEVPIGSLIQRGFIRPKDCDVLTAVSQFFNASCVP--VNNPKN----YPSALCALCVGDEKGRNKCVGSSQERYYGYSGAFRCLVEHAGDVAFVKHTTVFENTNGHNPEPWASHLRWQDYELLCPNGARAEVDQFQACNLAQMPSHAVMV-----RPDTNIFTVYGLLDKAQDLFGDDHNKNGFQMFDSSKYHSQDLLFKDATVRAVPV-REKTTYLDWLGPDYVVALEGM 704

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Mouse
Match: Trf (transferrin [Source:MGI Symbol;Acc:MGI:98821])

HSP 1 Score: 270.781 bits (691), Expect = 3.126e-79
Identity = 214/729 (29.36%), Postives = 318/729 (43.62%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLS----KMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR--CPFAGI-----KWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDD------------TSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQE--YFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIP 2216
            +KWC +SE E  KC      ++           +CV   S  DC+  ++   AD + LD G  Y A +    ++  A E Y     P   Q +Y +V VV KGT      L GK +C  G G + GW+ P+     K+ E R       +   K V+ FF SGSC   +    F  L       C  C         CS++ PF G  G+  CL      G    AF++  T+   L    +    Y+LLC     D T    ++Q E C   +  S  ++ +  + +  +  + L     +FG     S +F LF S             LG+           DL+F D+   F   +    ++   YL   +  AI       CP   I     KWC +S  E  KC    +  + K+      C    +T +C+  I +G AD MTLD    YI G+   LVP+  EYY                 YYAVA+ K +D  I  +N K K++CH+G  + +GW IP+ +    +            F E  ++ C PG          +    LC++C   G  +C P+ +E+Y G +GAFRC++E GDVAF +H TV DNT+G+NP +WA+N + +D+ELLCPDGTR     ++ C+L + P HV+V     S+ ++    + +  SQE  +  SD    F +F S     DL+F D       +P
Sbjct:   25 VKWCAVSEHENTKCISFRDHMKTVLPPDGP-RLACVKKTSYPDCIKAISASEADAMTLDGGWVYDAGLTPNNLKPVAAEFYGSVEHP---QTYYYAVAVVKKGTDFQLNQLEGKKSCHTGLGRSAGWVIPIGLLFCKLSEPR-------SPLEKAVSSFF-SGSCVPCADPVAFPKL-------CQLCPGCG-----CSSTQPFFGYVGAFKCLK----DGGGDVAFVKHTTIFEVLPEKADRDQ-YELLC----LDNTR-KPVDQYEDCYLARIPSHAVVARKNNGKEDLIWEILKVAQEHFGKGK--SKDFQLFSSP------------LGK-----------DLLFKDSA--FGLLRVPPRMDYRLYLGHNYVTAIRNQQEGVCPEGSIDNSPVKWCALSHLERTKCDEWSIISEGKI-----ECESAETTEDCIEKIVNGEADAMTLDGGHAYIAGQ-CGLVPVMAEYYESSNCAIPSQQGIFPKGYYAVAVVKASDTSITWNNLKGKKSCHTGVDRTAGWNIPMGMLYNRINH--------CKFDEFFSQGCAPGY---------EKNSTLCDLCI--GPLKCAPNNKEEYNGYTGAFRCLVEKGDVAFVKHQTVLDNTEGKNPAEWAKNLKQEDFELLCPDGTRKPVKDFASCHLAQAPNHVVV-----SRKEKAARVKAVLTSQETLFGGSDCTGNFCLFKST--TKDLLFRDDTKCFVKLP 660

HSP 2 Score: 171.4 bits (433), Expect = 4.611e-44
Identity = 110/353 (31.16%), Postives = 174/353 (49.29%), Query Frame = 3

Query: 1248 PFAGIKWCVISDDEMLKCRNMKLALDSKMLR--PEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYL-NLVPIAQEYYGD----DTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLE 2282
            P   +KWC +S+ E  KC + +  + + +    P   CV   S  +C++ IS   AD MTLD   +Y  G    NL P+A E+YG      T YYAVA+ K+      ++  + K++CH+G G+++GWVIP+ +     +       L  + S   + SC+P    DP          LC++C   G     P     ++G  GAF+C+ +  GDVAF +HTT+ +                D YELLC D TR     +  C L +IP H +V    K+  + D +W +L+ +QE+F    +  F +F+SP G+ DL+F DSA  L  +P  + +Y + L  ++   + N +
Sbjct:   21 PDKTVKWCAVSEHENTKCISFRDHMKTVLPPDGPRLACVKKTSYPDCIKAISASEADAMTLDGGWVYDAGLTPNNLKPVAAEFYGSVEHPQTYYYAVAVVKKGTD-FQLNQLEGKKSCHTGLGRSAGWVIPIGLLF--CKLSEPRSPLEKAVSSFFSGSCVP--CADPVAFP-----KLCQLCPGCGCSSTQP-----FFGYVGAFKCLKDGGGDVAFVKHTTIFEVL--------PEKADRDQYELLCLDNTRKPVDQYEDCYLARIPSHAVV--ARKNNGKEDLIWEILKVAQEHFGKGKSKDFQLFSSPLGK-DLLFKDSAFGLLRVPP-RMDYRLYLGHNYVTAIRNQQ 346

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Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLS----KMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR--CPFAGI-----KWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDD------------TSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQE--YFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIP 2216
            +KWC +SE E  KC      ++           +CV   S  DC+  ++   AD + LD G  Y A +    ++  A E Y     P   Q +Y +V VV KGT      L GK +C  G G + GW+ P+     K+ E R       +   K V+ FF SGSC   +    F  L       C  C         CS++ PF G  G+  CL      G    AF++  T+   L    +    Y+LLC     D T    ++Q E C   +  S  ++ +  + +  +  + L     +FG     S +F LF S             LG+           DL+F D+   F   +    ++   YL   +  AI       CP   I     KWC +S  E  KC    +  + K+      C    +T +C+  I +G AD MTLD    YI G+   LVP+  EYY                 YYAVA+ K +D  I  +N K K++CH+G  + +GW IP+ +    +            F E  ++ C PG          +    LC++C   G  +C P+ +E+Y G +GAFRC++E GDVAF +H TV DNT+G+NP +WA+N + +D+ELLCPDGTR     ++ C+L + P HV+V     S+ ++    + +  SQE  +  SD    F +F S     DL+F D       +P
Sbjct:   25 VKWCAVSEHENTKCISFRDHMKTVLPPDGP-RLACVKKTSYPDCIKAISASEADAMTLDGGWVYDAGLTPNNLKPVAAEFYGSVEHP---QTYYYAVAVVKKGTDFQLNQLEGKKSCHTGLGRSAGWVIPIGLLFCKLSEPR-------SPLEKAVSSFF-SGSCVPCADPVAFPKL-------CQLCPGCG-----CSSTQPFFGYVGAFKCLK----DGGGDVAFVKHTTIFEVLPEKADRDQ-YELLC----LDNTR-KPVDQYEDCYLARIPSHAVVARKNNGKEDLIWEILKVAQEHFGKGK--SKDFQLFSSP------------LGK-----------DLLFKDSA--FGLLRVPPRMDYRLYLGHNYVTAIRNQQEGVCPEGSIDNSPVKWCALSHLERTKCDEWSIISEGKI-----ECESAETTEDCIEKIVNGEADAMTLDGGHAYIAGQ-CGLVPVMAEYYESSNCAIPSQQGIFPKGYYAVAVVKASDTSITWNNLKGKKSCHTGVDRTAGWNIPMGMLYNRINH--------CKFDEFFSQGCAPGY---------EKNSTLCDLCI--GPLKCAPNNKEEYNGYTGAFRCLVEKGDVAFVKHQTVLDNTEGKNPAEWAKNLKQEDFELLCPDGTRKPVKDFASCHLAQAPNHVVV-----SRKEKAARVKAVLTSQETLFGGSDCTGNFCLFKST--TKDLLFRDDTKCFVKLP 660

HSP 2 Score: 171.4 bits (433), Expect = 4.611e-44
Identity = 110/353 (31.16%), Postives = 174/353 (49.29%), Query Frame = 3

Query: 1248 PFAGIKWCVISDDEMLKCRNMKLALDSKMLR--PEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYL-NLVPIAQEYYGD----DTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLE 2282
            P   +KWC +S+ E  KC + +  + + +    P   CV   S  +C++ IS   AD MTLD   +Y  G    NL P+A E+YG      T YYAVA+ K+      ++  + K++CH+G G+++GWVIP+ +     +       L  + S   + SC+P    DP          LC++C   G     P     ++G  GAF+C+ +  GDVAF +HTT+ +                D YELLC D TR     +  C L +IP H +V    K+  + D +W +L+ +QE+F    +  F +F+SP G+ DL+F DSA  L  +P  + +Y + L  ++   + N +
Sbjct:   21 PDKTVKWCAVSEHENTKCISFRDHMKTVLPPDGPRLACVKKTSYPDCIKAISASEADAMTLDGGWVYDAGLTPNNLKPVAAEFYGSVEHPQTYYYAVAVVKKGTD-FQLNQLEGKKSCHTGLGRSAGWVIPIGLLF--CKLSEPRSPLEKAVSSFFSGSCVP--CADPVAFP-----KLCQLCPGCGCSSTQP-----FFGYVGAFKCLKDGGGDVAFVKHTTIFEVL--------PEKADRDQYELLCLDNTRKPVDQYEDCYLARIPSHAVV--ARKNNGKEDLIWEILKVAQEHFGKGKSKDFQLFSSPLGK-DLLFKDSAFGLLRVPP-RMDYRLYLGHNYVTAIRNQQ 346

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Mouse
Match: 1300017J02Rik (RIKEN cDNA 1300017J02 gene [Source:MGI Symbol;Acc:MGI:1919025])

HSP 1 Score: 245.743 bits (626), Expect = 4.630e-70
Identity = 199/746 (26.68%), Postives = 313/746 (41.96%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRC--PFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTS---------------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQ--DRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASD--SNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            I+WCV+S+ E  KC+     ++           +CV   S  +C+  ++    D V +D  L   A + ++ ++    E Y    DP T    Y  V +  KGT      L GK +C  G G + GW  PLS ++ S            +     F S SC   +   +F +L       C  C      +  CS+ +P+ G+ G++ CL      G    +F++  T+   +    +    Y+LLC     D T    + + E C   +  S +++ + V  +    ++ L     +FG +   SS F LF S                 G+        DL+F+DA          + +++  YL  EF +A   + R       +KWC +   E  KC        S +      C    +  +C+     G AD M+LD    Y+ G +  LVP+  E Y    S               YY VA+ K++D GI   + + K++CH+  G + GW +P+ +        +Y+      F    +RSC PG   DP +P       LC +C  G      C  +  E Y+G SGA RC++E GDVAF +H TV  NTDG+NP  WA+  + +D+ELLC DGTR        C+L ++P   +    F  + + D + R+L   QE F  +     +F MF S     DL+FSD    L  +  +K  Y   L   +   ++N 
Sbjct:   25 IRWCVVSDHEATKCSSFRDNMKKVLPAGGP-AVTCVRKMSHPECIRDISANKVDAVTVDGALVAEADLPHHSLKPIMAEYYGSKDDPKT---HYYVVAMAKKGTGFQLNQLRGKKSCHTGLGWSAGWYVPLSTLLPS---------GSRETAAATFFSSSCVPCADGKMFPSL-------CQLCAGKGTDKCACSSREPYFGSWGALKCLQ----DGTADVSFVKHLTVFEAMPTKADRDQ-YELLC----MDNTR-RPVEEYEQCYLARVPSHVVVARSVDGKEDSIQELLRVAQEHFGKDK--SSPFQLFGS---------------PHGE--------DLLFTDAAHGLLRVPRKIDISL--YLGYEFLSAFRNLKRGLEDSQRVKWCAVGQQERTKCDQW-----SAVSGGALACATEETPEDCIAATMKGEADAMSLDGGFAYVAG-HCGLVPVLAENYLSTHSSGRLGSKCVNAPLEGYYVVAVVKKSDVGITWKSLQGKKSCHTAVGTSEGWNVPMGL--------IYNQTGSCKFDAFFSRSCAPG--SDPDSP-------LCALCVGGNNPAHMCAANNAEGYHGSSGALRCLVEKGDVAFMKHPTVLQNTDGKNPEPWAKGLKHEDFELLCLDGTRKPVTEAQSCHLARVPNRAV----FSRKDKADFVRRILFNQQELFGRNGFEYMMFQMFES--SAKDLLFSDDTECLSNL-QNKTTYKTYLGPQYLTLMDNF 683

HSP 2 Score: 179.104 bits (453), Expect = 1.008e-46
Identity = 119/355 (33.52%), Postives = 180/355 (50.70%), Query Frame = 3

Query: 1248 PFAGIKWCVISDDEMLKCR----NMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGG-KYLNLVPIAQEYYG--DD--TSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLE 2282
            P   I+WCV+SD E  KC     NMK  L +    P   CV  +S   C+R IS    D +T+D A +      + +L PI  EYYG  DD  T YY VA+AK+   G  ++  + K++CH+G G ++GW +P++  +        S     + +   + SC+P          GK   +LC++CA  G D+C   +RE Y+G  GA +C+ +   DV+F +H TV +      P    R    D YELLC D TR     + +C L ++P HV+V        + D +  LLR +QE+F  D ++ F +F SP+G  DL+F+D+A  L  +P  K + ++ L   F     NL+
Sbjct:   21 PEKTIRWCVVSDHEATKCSSFRDNMKKVLPAG--GPAVTCVRKMSHPECIRDISANKVDAVTVDGALVAEADLPHHSLKPIMAEYYGSKDDPKTHYYVVAMAKKG-TGFQLNQLRGKKSCHTGLGWSAGWYVPLSTLLP-------SGSRETAAATFFSSSCVPCA-------DGKMFPSLCQLCAGKGTDKCACSSREPYFGSWGALKCLQDGTADVSFVKHLTVFEAM----PTKADR----DQYELLCMDNTRRPVEEYEQCYLARVPSHVVVARSVDG--KEDSIQELLRVAQEHFGKDKSSPFQLFGSPHGE-DLLFTDAAHGLLRVPR-KIDISLYLGYEFLSAFRNLK 346

HSP 3 Score: 71.633 bits (174), Expect = 2.481e-12
Identity = 83/343 (24.20%), Postives = 140/343 (40.82%), Query Frame = 3

Query:   90 VENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDP---------ATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCS--NSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDT-LTNWLANNPN--LAGF----YQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTIL----NYFGPNGTLSSNFNLFQSNV 1052
            +E+ + +KWC + + E  KC        D  +  S    +C    +  DC+    +  AD ++LD G AY A  + G+     ENY               A ++ +Y   VV       +   L GK +C    GT+EGW  P+  +    +    +C       + FF S SCA GS         D  +  C+ C   ++    C+  N++ + G++G++ C     L  +   AF++  T L N    NP     G     ++LLC     DGT    + + ++C+  +  +R + ++          DF+  IL      FG NG     F +F+S+ 
Sbjct:  349 LEDSQRVKWCAVGQQERTKC--------DQWSAVSGGALACATEETPEDCIAATMKGEADAMSLDGGFAYVA-GHCGLVPVLAENYLSTHSSGRLGSKCVNAPLEGYYVVAVVKKSDVGITWKSLQGKKSCHTAVGTSEGWNVPMGLI----YNQTGSCK-----FDAFF-SRSCAPGS---------DPDSPLCALCVGGNNPAHMCAANNAEGYHGSSGALRC-----LVEKGDVAFMKHPTVLQNTDGKNPEPWAKGLKHEDFELLC----LDGTR-KPVTEAQSCHLARVPNRAVFSRKDKA------DFVRRILFNQQELFGRNGFEYMMFQMFESSA 647

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Mouse
Match: Ltf (lactotransferrin [Source:MGI Symbol;Acc:MGI:96837])

HSP 1 Score: 234.187 bits (596), Expect = 7.254e-66
Identity = 187/672 (27.83%), Postives = 290/672 (43.15%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQN-YGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIF---------QYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTS------------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAA--GGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVT 2048
            ++WC +S SE  KC +   ++R           SCV   S+  C+  +    AD + LD G  + A +  Y +R  A E Y     P T    Y +V VV   +      L G  +C  G G + GW  P+  +      N    + E + V+ FF S SC  G+    F  L       CS C  T  ++   S  +P++G AG++ CL           AF RG T+   L N       Y+LLCP    D T+   + + + C+  +  S  ++++  + +     + L      FG     +S F LF S                      P    DL+F ++ I F      V + ++         Q LN++ Q+ I +  R     + WC +  +E  KC        ++  R    C+   +T +C+  I  G AD M+LD   +Y  GK   LVP+  E      S            Y AVA  +R D G   S+ + K++CH+   + +GW IP+ +     +           F+E  ++SC PG   DP +       NLC +C     G+++C P+++E+Y G +GA RC+ E  G+VAF + +TV  NTDG+N  +WARN +  D+ELLC D TR        C+L   P H +V+
Sbjct:   24 VQWCAVSNSEEEKCLRWQNEMRKVGGPP----LSCVKKSSTRQCIQAIVTNRADAMTLDGGTMFDAGKPPYKLRPVAAEVYGTKEQPRT---HYYAVAVVKNSSNFHLNQLQGLRSCHTGIGRSAGWKIPIGTLRPYLNWNGPPASLE-EAVSKFF-SKSCVPGAQKDRFPNL-------CSSCAGTGANKCASSPEEPYSGYAGALRCLR----DNAGDVAFTRGSTVFEELPNKAERDQ-YKLLCP----DNTW-KPVTEYKECHLAQVPSHAVVSRSTNDKEEAIWELLRQSQEKFGKK--QASGFQLFAS----------------------PSGQKDLLFKESAIGFVRVPQKVDVGLYLTFSYTTSIQNLNKKQQDVIASKAR-----VTWCAVGSEEKRKCDQW-----NRASRGRVTCISFPTTEDCIVAIMKGDADAMSLDGGYIYTAGK-CGLVPVLAENQKSSKSNGLDCVNRPVEGYLAVAAVRREDAGFTWSSLRGKKSCHTAVDRTAGWNIPMGLLANQTR--------SCKFNEFFSQSCAPG--ADPKS-------NLCALCIGDEKGENKCAPNSKERYQGYTGALRCLAEKAGNVAFLKDSTVLQNTDGKNTEEWARNLKLKDFELLCLDDTRKPVTEAKNCHLAIAPNHAVVS 617

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. UniProt/SwissProt
Match: sp|P08582|TRFM_HUMAN (Melanotransferrin OS=Homo sapiens OX=9606 GN=MELTF PE=1 SV=2)

HSP 1 Score: 289.271 bits (739), Expect = 8.265e-85
Identity = 217/747 (29.05%), Postives = 350/747 (46.85%), Query Frame = 3

Query:  105 DIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNS--DPFAGNAGSMNCL-----DAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAM----HRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDD---TSYYAVAIAKR-ADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAG--GQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRD--EMWRLLRYSQEYFASDSNT-VFAMF-ASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            +++WC  S+ E  KC  +    R+     S     CV   S+  C+ L+  + AD + LD G  Y A + +G++    E Y+     +     Y +V VV + +  +   L G  +C  G     GW  P+  ++ES  +++  C+  +K V+ +F  GSC  G+    +      S   C  C   S     C  S  + +   +G+  CL     D A +   T      G TL +W      L+  ++LLC     DG+  + + +   C+  +  +  ++ +  +    I++  LN     F   G   S+F +F S              GQ           DL+F D+T     P  T +     +L  E+ +A+  +    +R P   ++WCV+S  E+ KC +M +A   + L+PE  CV   S  +CM  I     D +TL   ++Y  GK   LVP A E+Y  +    SYY VA+ +R +     +   + KR+CH+G G  +GW +PV   ++    R     ++ + SE    SC+P  + +P N     P +LC +C     G+++C+ +++E+YYG  GAFRC++EN GDVAF RHTTV DNT+G N   WA   RS+DYELLCP+G R +   ++ CNL +IP H ++      +P  +   ++ LL  +Q+ F  D N   F MF +S Y   DL+F D+ V   P+  +K  Y   L   +   +E +
Sbjct:   22 EVRWCATSDPEQHKCGNMSEAFREAGIQPS---LLCVRGTSADHCVQLIAAQEADAITLDGGAIYEAGKEHGLKPVVGEVYDQEVGTS-----YYAVAVVRRSSHVTIDTLKGVKSCHTGINRTVGWNVPVGYLVESGRLSVMGCDV-LKAVSDYF-GGSCVPGAGETSY------SESLCRLCRGDSSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSW--GQALLSQDFELLC----RDGSRAD-VTEWRQCHLARVPAHAVVVRADTDGGLIFR-LLNEGQRLFSHEG---SSFQMFSSEA-----------YGQK----------DLLFKDSTSEL-VPIATQTYEA--WLGHEYLHAMKGLLCDPNRLP-PYLRWCVLSTPEIQKCGDMAVAFRRQRLKPEIQCVSAKSPQHCMERIQAEQVDAVTLSGEDIYTAGKTYGLVPAAGEHYAPEDSSNSYYVVAVVRRDSSHAFTLDELRGKRSCHAGFGSPAGWDVPVGALIQRGFIRPKDCDVLTAVSEFFNASCVP--VNNPKN----YPSSLCALCVGDEQGRNKCVGNSQERYYGYRGAFRCLVENAGDVAFVRHTTVFDNTNGHNSEPWAAELRSEDYELLCPNGARAEVSQFAACNLAQIPPHAVMV-----RPDTNIFTVYGLLDKAQDLFGDDHNKNGFKMFDSSNYHGQDLLFKDATVRAVPV-GEKTTYRGWLGLDYVAALEGM 704

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. UniProt/SwissProt
Match: sp|O97490|TRFM_RABIT (Melanotransferrin OS=Oryctolagus cuniculus OX=9986 GN=MELTF PE=2 SV=1)

HSP 1 Score: 287.345 bits (734), Expect = 4.253e-84
Identity = 210/748 (28.07%), Postives = 350/748 (46.79%), Query Frame = 3

Query:  105 DIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNS--DPFAGNAGSMNCL-----DAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAM----HRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDD---TSYYAVAIAKRADK-GILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAG--GQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRD--EMWRLLRYSQEYFASDSNT-VFAMF-ASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLE 2282
            +++WC  SE E  KC  +    R+           CV   S+  C+ L+    AD + LD G  Y A + +G++    E Y+     +     Y +V VV + +  +   L G  +C  G     GW  P+  +++S  +++  C+  +K V+ +F  GSC  G+    +      S   C  C   +     C  S  + +   +G+  CL     D A +   T      G TL +W   +  ++  ++LLC     DG+  + + + + C+  +  +  ++ +  +    I++  LN     F   G   S+F +F S              GQ           +L+F D+T+    P  T +     +L  E+ +A+  +    +R P   ++WCV+S  E+ KC +M +A   + L+PE  CV   S  +CM  I  G  D +TL+  +++  GK   L+P A E Y  D    SY+ VA+ KR       +   + KR+CH G G  +GW +PV   +     R  +  ++ +  +    SC+P       N   K P +LC +C     G+++C  +++E+YYGDSGAFRC++E  GDVAF +HTT+ DNT+G NP  WA + RS DYELLCP+G R + + ++ CNL +IP H ++      +P  +   ++ LL  +Q+ F  D N   F MF +S Y   DL+F D+ V   P+  ++  Y   L   +   +E ++
Sbjct:   22 EVRWCTASEPEQQKCEDMSQAFRE---AGLQPALLCVQGTSADHCVQLIAAHEADAITLDGGAIYEAGKEHGLKPVVGEVYDQEVGTS-----YYAVAVVKRSSNVTINTLRGVKSCHTGINRTVGWNVPVGYLVDSGRLSVMGCD-VLKAVSEYF-GGSCVPGAGETRY------SESLCRLCRGDTSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGRTLPSW--GHMLMSRDFELLC----RDGSRAS-VTEWQHCHLARVPAHAVVVRADTDAGLIFR-LLNEGQRLFSHEG---SSFQMFSSEA-----------YGQK----------NLLFKDSTLEL-VPIATQTYEA--WLGPEYLHAMKGLLCDPNRLP-PYLRWCVLSTPEIQKCGDMAVAFSRQRLKPEIQCVSAESPQHCMEQIQAGHIDAVTLNGEDIHTAGKTYGLIPAAGELYAADDRSNSYFVVAVVKRDSAYAFTVDELRGKRSCHPGFGSPAGWDVPVGALIHWGYIRPRNCDVLTAVGQFFNASCVP------VNNPKKYPSSLCALCVGDEQGRNKCTGNSQERYYGDSGAFRCLVEGAGDVAFVKHTTIFDNTNGHNPEPWAAHLRSQDYELLCPNGARAEAHQFAACNLAQIPSHAVMV-----RPDTNIFTVYGLLDKAQDLFGDDHNKNGFKMFDSSSYHGRDLLFKDATVRAVPV-GERTTYQDWLGPDYVAALEGMQ 705

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. UniProt/SwissProt
Match: sp|A5A6I6|TRFE_PANTR (Serotransferrin OS=Pan troglodytes OX=9598 GN=TF PE=2 SV=1)

HSP 1 Score: 281.567 bits (719), Expect = 2.409e-82
Identity = 216/744 (29.03%), Postives = 328/744 (44.09%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR--CPFAG------IKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGD--------DTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFAS---DSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            ++WC +SE E  KC      ++     S   + +CV   S  DC+  +    AD V LD GL Y A +    ++    E Y    DP   Q FY +V VV K +      L GK +C  G G + GW  P+  +    + ++      ++     F SGSCA  +    F  L       C  C         CS  + + G +G+  CL      G    AF++  T+   LAN  +    Y+LLC     D T    +++ + C+  +  S  ++ + +  +  +  + LN    +FG +   S  F LF                      S+P    DL+F D+   F   +    ++   YL  E+  AI  +    CP A       +KWC +S  E LKC    +    K+      CV   +T +C+  I +G AD M+LD   +YI GK   LVP+  E Y          +  Y+AVA+ K++   +   N K K++CH+  G+ +GW IP+ +        +Y+      F E  +  C PG          K   +LC++C   G + C P+ +E YYG +GAFRC++E GDVAF +H TV  NT G+NP  WA+N    DYELLC DGTR     ++ C+L + P H +VT     + +   + ++LR  Q  F S   D +  F +F S     DL+F D  V L  +  D+  Y   L   + + V NL
Sbjct:   25 VRWCAVSEHEATKCQSFRDHMKSVIP-SDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDP---QTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLL----YCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQL-------CQLCPGCG-----CSTLNQYFGYSGAFKCLK----DGAGDVAFVKHSTIFENLANKADRDQ-YELLC----LDNTR-KPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDK--SKEFQLF----------------------SSPHG-KDLLFKDSAHGFL--KVPPRMDAKMYLGYEYVTAIRNLREGTCPEATTDECKPVKWCALSHHERLKCDEWSVNSVGKI-----ECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGK-CGLVPVLAENYNKNDNCEDTPEAGYFAVAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIPMGL--------LYNKINHCRFDEFFSEGCAPG---------SKKDSSLCKLCMGSGPNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVKEYANCHLARAPNHAVVT----RKDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRSE--TKDLLFRDDTVCLAKL-HDRNTYEKYLGEEYVKAVGNL 681

HSP 2 Score: 178.333 bits (451), Expect = 1.542e-45
Identity = 115/355 (32.39%), Postives = 181/355 (50.99%), Query Frame = 3

Query: 1248 PFAGIKWCVISDDEMLKCRNMKLALDSKMLR--PEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYL---NLVPIAQEYYGD----DTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIA-METVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            P   ++WC +S+ E  KC++ +  + S +    P   CV   S  +C+R I+   AD +TLDA  +Y    YL   NL P+  E+YG      T YYAVA+ K+ D G  ++  + K++CH+G G+++GW IP+ +   +  + R   ++ V +F    + SC P   G  +         LC++C       C   T  QY+G SGAF+C+ +  GDVAF +H+T+ +N         A     D YELLC D TR     +  C+L ++P H +V        + D +W LL  +QE+F  D +  F +F+SP+G+ DL+F DSA     +P  + +  M L   +   + NL
Sbjct:   21 PDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDA--YLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANF---FSGSCAPCADGTDFP-------QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFEN--------LANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGG--KEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGK-DLLFKDSAHGFLKVPP-RMDAKMYLGYEYVTAIRNL 345

HSP 3 Score: 77.411 bits (189), Expect = 3.430e-13
Identity = 99/395 (25.06%), Postives = 156/395 (39.49%), Query Frame = 3

Query:   90 VENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTD-PATMQLFYTSVVVVIKGTISSPVI---LNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCL----DAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGT-LSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRC 1247
             +  + +KWC +S  E +KC        D  +++S     CV   ++ DC+  +    AD ++LD G  Y A +  G+     ENYN N +   T +  Y +V VV K   +S +    L GK +C    G   GW  P+  +    +  I  C       + FF+ G CA GS          +S+L C  C  +  +    +N + + G  G+  CL    D A +  QT      G     W A N N    Y+LLC     DGT    + +   C+  +  +  ++T+    +       L    + FG N T  S NF LF+S                           DL+F D T+      D  +    +YL +E+  A+  + +C
Sbjct:  355 TDECKPVKWCALSHHERLKC--------DEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGK-CGLVPVLAENYNKNDNCEDTPEAGYFAVAVVKKS--ASDLTWDNLKGKKSCHTAVGRTAGWNIPMGLL----YNKINHCR-----FDEFFSEG-CAPGSKK--------DSSL-CKLCMGSGPNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPW-AKNLNEKD-YELLC----LDGTR-KPVKEYANCHLARAPNHAVVTR--KDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRSET------------------------KDLLFRDDTVCLAKLHDRNTYE--KYLGEEYVKAVGNLRKC 684

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. UniProt/SwissProt
Match: sp|P02787|TRFE_HUMAN (Serotransferrin OS=Homo sapiens OX=9606 GN=TF PE=1 SV=3)

HSP 1 Score: 281.182 bits (718), Expect = 3.859e-82
Identity = 215/744 (28.90%), Postives = 328/744 (44.09%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR--CPFAG------IKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGD--------DTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFAS---DSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            ++WC +SE E  KC      ++     S   + +CV   S  DC+  +    AD V LD GL Y A +    ++    E Y    DP   Q FY +V VV K +      L GK +C  G G + GW  P+  +    + ++      ++     F SGSCA  +    F  L       C  C         CS  + + G +G+  CL      G    AF++  T+   LAN  +    Y+LLC     D T    +++ + C+  +  S  ++ + +  +  +  + LN    +FG +   S  F LF                      S+P    DL+F D+   F   +    ++   YL  E+  AI  +    CP A       +KWC +S  E LKC    +    K+      CV   +T +C+  I +G AD M+LD   +YI GK   LVP+  E Y          +  Y+A+A+ K++   +   N K K++CH+  G+ +GW IP+ +        +Y+      F E  +  C PG          K   +LC++C   G + C P+ +E YYG +GAFRC++E GDVAF +H TV  NT G+NP  WA+N    DYELLC DGTR     ++ C+L + P H +VT     + +   + ++LR  Q  F S   D +  F +F S     DL+F D  V L  +  D+  Y   L   + + V NL
Sbjct:   25 VRWCAVSEHEATKCQSFRDHMKSVIP-SDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDP---QTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLL----YCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQL-------CQLCPGCG-----CSTLNQYFGYSGAFKCLK----DGAGDVAFVKHSTIFENLANKADRDQ-YELLC----LDNTR-KPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDK--SKEFQLF----------------------SSPHG-KDLLFKDSAHGFL--KVPPRMDAKMYLGYEYVTAIRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEWSVNSVGKI-----ECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGK-CGLVPVLAENYNKSDNCEDTPEAGYFAIAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIPMGL--------LYNKINHCRFDEFFSEGCAPG---------SKKDSSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT----RKDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRSE--TKDLLFRDDTVCLAKL-HDRNTYEKYLGEEYVKAVGNL 681

HSP 2 Score: 178.333 bits (451), Expect = 1.472e-45
Identity = 115/355 (32.39%), Postives = 181/355 (50.99%), Query Frame = 3

Query: 1248 PFAGIKWCVISDDEMLKCRNMKLALDSKMLR--PEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYL---NLVPIAQEYYGD----DTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIA-METVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            P   ++WC +S+ E  KC++ +  + S +    P   CV   S  +C+R I+   AD +TLDA  +Y    YL   NL P+  E+YG      T YYAVA+ K+ D G  ++  + K++CH+G G+++GW IP+ +   +  + R   ++ V +F    + SC P   G  +         LC++C       C   T  QY+G SGAF+C+ +  GDVAF +H+T+ +N         A     D YELLC D TR     +  C+L ++P H +V        + D +W LL  +QE+F  D +  F +F+SP+G+ DL+F DSA     +P  + +  M L   +   + NL
Sbjct:   21 PDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDA--YLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANF---FSGSCAPCADGTDFP-------QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENL--------ANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGG--KEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGK-DLLFKDSAHGFLKVPP-RMDAKMYLGYEYVTAIRNL 345

HSP 3 Score: 73.9442 bits (180), Expect = 3.158e-12
Identity = 97/395 (24.56%), Postives = 156/395 (39.49%), Query Frame = 3

Query:   90 VENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTD-PATMQLFYTSVVVVIKGTISSPVI---LNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCL----DAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGT-LSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRC 1247
             +  + +KWC +S  E +KC        D  +++S     CV   ++ DC+  +    AD ++LD G  Y A +  G+     ENYN + +   T +  Y ++ VV K   +S +    L GK +C    G   GW  P+  +    +  I  C       + FF+ G CA GS          +S+L C  C  +  +    +N + + G  G+  CL    D A +  QT      G     W A N N    Y+LLC     DGT    + +   C+  +  +  ++T+    +       L    + FG N T  S NF LF+S                           DL+F D T+      D  +    +YL +E+  A+  + +C
Sbjct:  355 TDECKPVKWCALSHHERLKC--------DEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGK-CGLVPVLAENYNKSDNCEDTPEAGYFAIAVVKKS--ASDLTWDNLKGKKSCHTAVGRTAGWNIPMGLL----YNKINHCR-----FDEFFSEG-CAPGSKK--------DSSL-CKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPW-AKNLNEKD-YELLC----LDGTR-KPVEEYANCHLARAPNHAVVTR--KDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRSET------------------------KDLLFRDDTVCLAKLHDRNTYE--KYLGEEYVKAVGNLRKC 684

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. UniProt/SwissProt
Match: sp|Q9R0R1|TRFM_MOUSE (Melanotransferrin OS=Mus musculus OX=10090 GN=Meltf PE=2 SV=1)

HSP 1 Score: 280.796 bits (717), Expect = 1.085e-81
Identity = 211/754 (27.98%), Postives = 346/754 (45.89%), Query Frame = 3

Query:   99 VEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNS--DPFAGNAGSMNCL-----DAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTL-----SSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAM----HRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDD---TSYYAVAIAKR-ADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAA--GGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRD--EMWRLLRYSQEYFASDSNT-VFAMF-ASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            V +++WC IS++E  KC  +      F       +  CV   S+  C+ L+ ++ AD + LD G  Y A + +G++    E Y+ +   +     Y +V VV + +  +   L G  +C  G     GW  P+  ++ES  +++  C+  +K V  +F  GSC  G+          +S   C  C   S     C  S  + +   +G+  CL     D A +   T      G+TL +W      ++  +QLLC     DG+      + +   W +     +    V  R  +    +  +LN     G L      S+F +F S                           +L+F D+T+         + N   +L QE+  A+  +    +R P   ++WCV+S  E+ KC +M +A   + L+PE  CV   S  +CM  I  G  D +TL   ++Y  GK   LVP A E Y ++    SY+ VA+A+R +     +   + KR+CH   G  +GW +P+   ++    R     ++ + S+    SC+P  + +P N     P  LC +C     G+++C+  ++E+YYG SGAFRC++E+ GDVAF +HTTV +NT+G NP  WA + R  DYELLCP+G R +   +  CNL ++P H ++      +P  +   ++ LL  +Q+ F  D N   F MF +S Y   DL+F D+ V   P+  +K  Y   L   +   +E +
Sbjct:   20 VMEVQWCTISDAEQQKCKDMSEA---FQGAGIRPSLLCVQGNSADHCVQLIKEQKADAITLDGGAIYEAGKEHGLKPVVGEVYDQDIGTS-----YYAVAVVRRNSNVTINTLKGVKSCHTGINRTVGWNVPVGYLVESGHLSVMGCD-VLKAVGDYF-GGSCVPGTGET------SHSESLCRLCRGDSSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGNTLPSW--GKSLMSEDFQLLC----RDGS------RADITEWRRCHLAKVPAHAVVVRGDMDGGLIFQLLN----EGQLLFSHEDSSFQMFSSKAYSQ---------------------KNLLFKDSTLELV---PIATQNYEAWLGQEYLQAMKGLLCDPNRLPHY-LRWCVLSAPEIQKCGDMAVAFSRQNLKPEIQCVSAESPEHCMEQIQAGHTDAVTLRGEDIYRAGKVYGLVPAAGELYAEEDRSNSYFVVAVARRDSSYSFTLDELRGKRSCHPYLGSPAGWEVPIGSLIQRGFIRPKDCDVLTAVSQFFNASCVP--VNNPKN----YPSALCALCVGDEKGRNKCVGSSQERYYGYSGAFRCLVEHAGDVAFVKHTTVFENTNGHNPEPWASHLRWQDYELLCPNGARAEVDQFQACNLAQMPSHAVMV-----RPDTNIFTVYGLLDKAQDLFGDDHNKNGFQMFDSSKYHSQDLLFKDATVRAVPV-REKTTYLDWLGPDYVVALEGM 704

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. TrEMBL
Match: A0A3Q0KPX0 (Family S60 non-peptidase homologue (S60 family) OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 656.751 bits (1693), Expect = 0.000e+0
Identity = 322/745 (43.22%), Postives = 464/745 (62.28%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIES-RWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQT----SAAFLRGDTLTNWLANNPNLAGF----YQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPKKSGLF 2315
            ++WC +S  E IKC +L + I+    IS+ YN +C+L    F+CM L+N++ AD++NLDVGLAYY    Y +R  AVENY  +  P    L+Y +V++   G    P  L GK  C AGAGTAEGW+ P+  +I   + + +  CN+ V+ +  +    SC   S + +FN  GDN+   C  C NT  S  +C + D ++GN G++ CL     + ++    + AFLR   +   LA+     GF    Y+LLCP+   +G +   ++    CNWGK  SRM+MT L+ + V +Y DFL  ++  FGP+GT  S FNLF S+    ++ D                 + LMFSD T + Y P  T +   +++++  F+ A+  +  CP   + WCVI + EM KC+ M  A  +K ++P+ +C+   ST +CM+LI DG+AD++TL+A +LYI GKY +LVP+  E YG+   YYAVAI ++ + G+LISNW+++RTCHSG GKA+GW+IP+N  ++T Q  V    LV++F ELI+R+CIPGIL   Y+ TG N +NLCE+C  G  DRC  D  E YYGD+GAFRC++E  D+AFARHTTVH NT GRNP  WAR+ R D+YE+LCPDG R + + W  CNLGKIP +V+VT  +KS+ +R  MWRLL+Y QEY++SD++ VF MF S +G+ DL+F+D   SL  IP + Q Y   L + F + VENL++I  P ++GL+
Sbjct:   23 VRWCSVSPEEEIKCNRLSSVIQSTPTISNKYNLTCILGSDEFNCMKLINEKQADLMNLDVGLAYYGSSLYSLRPIAVENYAISNAPNARNLYYYAVMIKPIGISVDPTNLRGKEICSAGAGTAEGWVMPVGTLISDLKAIPVIQCNSVVQNLIRYL-GDSCIPNSLSEIFNPFGDNTQEVCRLCYNTGLSD-WCGSLDRYSGNQGALRCLREYTENFESKYKPAVAFLRDQEIE--LASGD---GFPIENYELLCPSKMPNGIWTANISSSADCNWGKIPSRMIMTSLIQSDVTVYIDFLELLVQNFGPSGTSVSAFNLFSSSGYTTVNGD--------------NATHHLMFSDFTKSIYIPPVTETETYYRWIDPSFKKALEKLESCPLPTLGWCVIDEFEMSKCQRMSSAFSAKRIQPDMFCLQANSTIDCMKLIKDGYADMVTLEAGDLYIAGKYFDLVPVVSENYGNGPFYYAVAIVEKVNPGLLISNWRHRRTCHSGVGKAAGWIIPLNTVLDTSQVIVLDGHLVHAFGELISRACIPGILNKAYDHTGTNSLNLCELCTGGNADRCRRDNLELYYGDAGAFRCLIEGADIAFARHTTVHTNTGGRNPNFWARDLREDNYEILCPDGRRAEVHEWLTCNLGKIPSNVVVTANYKSENERTNMWRLLQYGQEYYSSDNDPVFQMFNSEFGQKDLIFNDDTESLNLIPWENQTYEAWLGQRFIQMVENLKVISNPYENGLY 746

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. TrEMBL
Match: G4VHQ7 (Family S60 non-peptidase homologue (S60 family) OS=Schistosoma mansoni OX=6183 GN=Smp_151060 PE=3 SV=1)

HSP 1 Score: 656.366 bits (1692), Expect = 0.000e+0
Identity = 322/745 (43.22%), Postives = 464/745 (62.28%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIES-RWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQT----SAAFLRGDTLTNWLANNPNLAGF----YQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPKKSGLF 2315
            ++WC +S  E IKC +L + I+    IS+ YN +C+L    F+CM L+N++ AD++NLDVGLAYY    Y +R  AVENY  +  P    L+Y +V++   G    P  L GK  C AGAGTAEGW+ P+  +I   + + +  CN+ V+ +  +    SC   S + +FN  GDN+   C  C NT  S  +C + D ++GN G++ CL     + ++    + AFLR   +   LA+     GF    Y+LLCP+   +G +   ++    CNWGK  SRM+MT L+ + V +Y DFL  ++  FGP+GT  S FNLF S+    ++ D                 + LMFSD T + Y P  T +   +++++  F+ A+  +  CP   + WCVI + EM KC+ M  A  +K ++P+ +C+   ST +CM+LI DG+AD++TL+A +LYI GKY +LVP+  E YG+   YYAVAI ++ + G+LISNW+++RTCHSG GKA+GW+IP+N  ++T Q  V    LV++F ELI+R+CIPGIL   Y+ TG N +NLCE+C  G  DRC  D  E YYGD+GAFRC++E  D+AFARHTTVH NT GRNP  WAR+ R D+YE+LCPDG R + + W  CNLGKIP +V+VT  +KS+ +R  MWRLL+Y QEY++SD++ VF MF S +G+ DL+F+D   SL  IP + Q Y   L + F + VENL++I  P ++GL+
Sbjct:   17 VRWCSVSPEEEIKCNRLSSVIQSTPTISNKYNLTCILGSDEFNCMKLINEKQADLMNLDVGLAYYGSSLYSLRPIAVENYAISNAPNARNLYYYAVMIKPIGISVDPTNLRGKEICSAGAGTAEGWVMPVGTLISDLKAIPVIQCNSVVQNLIRYL-GDSCIPNSLSEIFNPFGDNTQEVCRLCYNTGLSD-WCGSLDRYSGNQGALRCLREYTENFESKYKPAVAFLRDQEIE--LASGD---GFPIENYELLCPSKMPNGIWTANISSSADCNWGKIPSRMIMTSLIQSDVTVYIDFLELLVQNFGPSGTSVSAFNLFSSSGYTTVNGD--------------NATHHLMFSDFTKSIYIPPVTETETYYRWIDPSFKKALEKLESCPLPTLGWCVIDEFEMSKCQRMSSAFSAKRIQPDMFCLQANSTIDCMKLIKDGYADMVTLEAGDLYIAGKYFDLVPVVSENYGNGPFYYAVAIVEKVNPGLLISNWRHRRTCHSGVGKAAGWIIPLNTVLDTRQVIVLDGHLVHAFGELISRACIPGILNKAYDHTGTNSLNLCELCTGGNADRCRRDNLELYYGDAGAFRCLIEGADIAFARHTTVHTNTGGRNPNFWARDLREDNYEILCPDGRRAEVHEWLTCNLGKIPSNVVVTANYKSENERTNMWRLLQYGQEYYSSDNDPVFQMFNSEFGQKDLIFNDDTESLNLIPWENQTYEAWLGQRFIQMVENLKVISNPYENGLY 740

HSP 2 Score: 135.576 bits (340), Expect = 6.744e-29
Identity = 110/380 (28.95%), Postives = 168/380 (44.21%), Query Frame = 3

Query: 1251 FAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFY---CVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTS-------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQF--RVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEIC-AAGGQDRCLPDTREQYYGDSGAFRCMLENGD---------VAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGT-----RVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASP--------YGRSDLMFSDSAVSLK-PIPADKQNYTMILDRSFARQVENLE 2282
             A ++WC +S +E +KC  +   + S       Y   C++G    NCM+LI++  ADLM LD    Y G    +L PIA E Y    +       YYAV I K     +  +N + K  C +GAG A GWV+PV   +  ++    +  + +V +    +  SCIP  L + +NP G N   +C +C   G  D C   + ++Y G+ GA RC+ E  +         VAF R   +   +    P+        ++YELLCP          +  S + CN GKIP  +I+T   +S       +  L       +  S + F +F+S              LMFSD   S+  P   + + Y   +D SF + +E LE
Sbjct:   14 LATVRWCSVSPEEEIKCNRLSSVIQSTPTISNKYNLTCILGSDEFNCMKLINEKQADLMNLDVGLAYYGSSLYSLRPIAVENYAISNAPNARNLYYYAVMI-KPIGISVDPTNLRGKEICSAGAGTAEGWVMPVGTLISDLKAIPVIQCNSVVQNLIRYLGDSCIPNSLSEIFNPFGDNTQEVCRLCYNTGLSDWC--GSLDRYSGNQGALRCLREYTENFESKYKPAVAFLRDQEIELASGDGFPI--------ENYELLCPSKMPNGIWTANISSSADCNWGKIPSRMIMTSLIQSDVTVYIDFLELLVQNFGPSGTSVSAFNLFSSSGYTTVNGDNATHHLMFSDFTKSIYIPPVTETETYYRWIDPSFKKALEKLE 382

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. TrEMBL
Match: A0A4Z2D8K1 (Melanotransferrin OS=Schistosoma japonicum OX=6182 GN=EWB00_003494 PE=4 SV=1)

HSP 1 Score: 654.44 bits (1687), Expect = 0.000e+0
Identity = 327/745 (43.89%), Postives = 461/745 (61.88%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIES-RWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTS----AAFLRGDTLTNWLANNPNLAGF----YQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPKKSGLF 2315
            I+WC  S  E IKC +L + I+    IS  YN +C+     F+CM L+N++ AD+VNLDVGLAYY    Y +R  AVENY  +  P    LFY +V+V   G    P  L GK  C AGAGTAEGW+ P+  +I   + + +T CN+ V+ +  +    SC   S + +FN  GDN+   C  C NT  S  +C++ D +AGN G++ CL     + ++      AFLR   +   LA+     GF    Y+LLCPT   +G++  +      CNWG+  SRM+MT L+ + + +Y  FL  ++ +FG NG  +S FNLF S             +G T  ++     + LMFSD T N Y P  T +   +++++  F+ A+  +  CP   + WCVI + EM KC+ M  A  +K ++PE +C+   ST +CM+LI DG+AD++TL+A +LYI GKY +LVPI  E YG+   YYAVAI ++ + G+LISNW+++RTCHSG GKA+GW+IP+N  ++T Q  V    LV++F ELI+R+C+PGIL   Y+ TG N +NLCE+C  G  DRC  D  E YYGD+GAFRC++E  D+AFARHTTVH NT GRNP  WAR+ R D+YE+LCPDG R + + WS CNLGKI  +V+VT  +KS+ +R  MWRLL+Y QEY++SDS+ VF MF S +G+ DL+F+D   SL  IP + Q Y   L + F + VENL++I    ++GL+
Sbjct:   21 IRWCSTSPEELIKCNRLSSVIQTIPAISHQYNLTCISGSDEFNCMKLINEKHADLVNLDVGLAYYGSSLYSLRPVAVENYAVSNAPNARNLFYYAVMVKPIGISVDPTNLRGKEICSAGAGTAEGWVMPVGTLISDLKAIPVTQCNSVVQNLIRYL-GDSCIPNSLSEIFNPFGDNTQEVCRLCYNTGLSD-WCASLDRYAGNQGALRCLREYTENYESKYKPVVAFLRDQEID--LASGD---GFPIENYELLCPTKFPNGSWTASTASSANCNWGRIPSRMIMTSLIQSDITVYTKFLELLVQHFGLNGISASMFNLFSS-------------IGYT-TSNGNNVTHHLMFSDFTKNIYIPSTTETETYYRWIDPSFKKALKKLESCPLPTLGWCVIDEFEMSKCQRMSSAFSAKRIQPEMFCLQANSTIDCMKLIKDGYADMVTLEAGDLYIAGKYFDLVPIVAENYGNGPYYYAVAIVEKVNPGLLISNWRHRRTCHSGVGKAAGWIIPLNTVLDTRQVIVLDGHLVHAFGELISRACVPGILNKAYDQTGTNSLNLCELCTGGNADRCHRDNLELYYGDAGAFRCLIEGADIAFARHTTVHSNTGGRNPNFWARDLREDNYEILCPDGRRAEAHDWSTCNLGKISSNVVVTANYKSENERTNMWRLLQYGQEYYSSDSDPVFQMFNSEFGQKDLIFNDDTESLHLIPWENQTYEAWLGKRFIQIVENLQVISNQYENGLY 744

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. TrEMBL
Match: A0A4S2MD44 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000888 PE=4 SV=1)

HSP 1 Score: 653.284 bits (1684), Expect = 0.000e+0
Identity = 322/753 (42.76%), Postives = 456/753 (60.56%), Query Frame = 3

Query:   87 HVENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMI-ESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQT----SAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALN-QIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPKKSGLFYANS 2327
             V    +++WCV +E E  KC KL   I     ++  Y  +C+  +  F CM L++ R AD++NLD GLAYY    Y +R  AVENY  +  P   +LFY + VVV K     P+ L GK  C AGAGTAEGW+ P  K+  + R + +T CN+ V+ + G+    SC   S + VFN  GDN+   C  C N      +C+  D +A N G++ CL     + ++    +AAF+R   +     +   +A  Y+LLCPT QADGT+    N     C+WG+  +RM+MT L    V  + +FL T++ YFGP+G+    F+LFQS                 G+   P   YDLMFSD T N + P +  +   +++++  F + +  + +CP   + WCVI   EM KC  MK A  ++ ++P+  C+   S  +CMRLI +G+AD++TL+A +LY  GKY +LVPI  E YGD   Y+AVA+ K+ + G+L+SNW+++ TCHSG GKA+GW++PVN+ ++T Q  V +  L+Y+F+ELI+R+CIPGIL  P++ TGKN +NLCE C  G +D C  D +E YYGD+GAFRCM E GD+AF RHTTVH NT GRNP  WARN R DDYELLC DG R +   W+ CNL +IP  V+VT  +KS+ +R  MWRLL+Y QEY+++D N +F MF S +G++DL+FSD   SL  IP + Q YT  L + F + VENLE+     ++GL+ A  
Sbjct:   21 QVTEAFNVRWCVYTEPEIRKCEKLRQSITTIPQLAMMYTLTCIAGQDEFQCMRLIHSREADLINLDAGLAYYGSSLYSLRPIAVENYALDNSPGVRELFYYANVVVPKHLNPVPINLRGKDICSAGAGTAEGWVMPFGKLFADLRTIPVTQCNSVVRNLIGYL-GDSCIPNSLSEVFNPFGDNTQEVCQLCANRG-LESWCTTRDRYARNHGALRCLREYTENIESLVKPTAAFVRAREIELASVDGFPMAD-YKLLCPTIQADGTWTADFNASTTTCHWGQIPARMIMTILTEPNVTEFNNFLTTLVQYFGPSGSHLQTFSLFQST--------------GYGNPDEPGQTYDLMFSDFTKNIFVPPEEETATYYRWISPNFLDELQKLEQCPLPTMNWCVIDQFEMAKCGRMKSAFAARRIQPDLNCIQADSAIDCMRLIQEGYADMITLEAGDLYAAGKYFDLVPIVAENYGDGPFYHAVAVVKKVNPGLLVSNWRHRFTCHSGVGKATGWIVPVNLVLDTRQVIVLNGHLLYAFAELISRACIPGILNAPFDRTGKNNLNLCERCTGGNKDLCRRDHQELYYGDAGAFRCMTEGGDIAFTRHTTVHMNTAGRNPDYWARNLREDDYELLCADGRRANVDQWATCNLARIPSSVVVTASYKSENERTNMWRLLQYGQEYYSADKNPIFQMFDSGFGQTDLIFSDDTESLSLIPWENQTYTRWLGQRFLQLVENLEVTANLYEAGLYSAKE 756

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. TrEMBL
Match: A0A075AIS8 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_01774 PE=4 SV=1)

HSP 1 Score: 651.744 bits (1680), Expect = 0.000e+0
Identity = 320/746 (42.90%), Postives = 454/746 (60.86%), Query Frame = 3

Query:  105 DIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMI-ESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQT----SAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALN-QIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPKKSGLFYAN 2324
            +++WCV +E E  KC KL   I     +S  Y  +C+  +  F CM L++ R AD++NLD GLAYY    Y +R  AVENY  +  P   +LFY + VVV K     P  L GK  C AGAGTAEGW+ P  K+  + R + +T CN+ V+ + G+    SC   S + VFN  GDN+   C  C N      +C+  D +A N G++ CL     + ++    +AAF+R   +     +   +A  Y+LLCPT QADGT+    N     C+WG+  +RM+MT L    V  + +FL T++ YFGP+G+    F+LFQS                 G+   P   YDLMFSD T N + P +  +   +++++  F + +  + +CP   + WCVI   EM KC  MK A  ++ ++P+  C+   S  +CMRLI +G+AD++TL+A +LY  GKY +LVPI  E YGD   Y+AVA+ K+ + G+L+SNW+++ TCHSG GKA+GW++P+N+ ++T Q  V +  L+Y+F+ELI+R+C+PGIL  P++ TGKN +NLCE C  G +D C  D +E YYGD+GAFRCM E GD+AF RHTTVH NT GRNP  WARN R DDYELLC DG R +   W+ CNL +IP  V+VT  +KS+ +R  MWRLL+Y QEY+++D N +F MF S +G++DL+FSD   SL  IP + Q YT  L + F + VENLE+     ++GL+ A 
Sbjct:  167 NVRWCVYTEPEIRKCEKLRQSITTIPQLSMMYTLTCIAGQDEFQCMRLIHSREADLINLDAGLAYYGSSLYSLRPIAVENYALDNSPGVRELFYYANVVVPKHLNPVPTNLRGKDICSAGAGTAEGWVMPFGKLFADLRTIPVTQCNSVVRNLIGYL-GDSCIPNSLSEVFNPFGDNTQEVCQLCANRG-LETWCTTRDRYARNHGALRCLREYTENIESLVKPTAAFVRAREIELASVDGFPMAD-YKLLCPTIQADGTWTADFNASTTTCHWGQIPARMIMTILTEPNVTEFNNFLTTLVQYFGPSGSHLQTFSLFQST--------------GYGNPDEPGQTYDLMFSDFTRNIFVPPEEETATYYRWISPNFLDELQKLEQCPLPTMNWCVIDQFEMAKCGRMKSAFAARRIQPDLNCIQADSAIDCMRLIQEGYADMITLEAGDLYAAGKYFDLVPIVAENYGDGPFYHAVAVVKKVNPGLLVSNWRHRFTCHSGVGKATGWIVPINLVLDTRQVIVLNGHLLYAFAELISRACVPGILNAPFDRTGKNNLNLCERCTGGNKDLCRRDHQELYYGDAGAFRCMTEGGDIAFTRHTTVHMNTAGRNPDYWARNLREDDYELLCADGRRANIDQWATCNLARIPSSVVVTASYKSENERTNMWRLLQYGQEYYSADKNPIFQMFDSGFGQTDLIFSDDTESLSLIPWENQTYTRWLGQRFLQLVENLEVTANLYEAGLYSAK 895

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Cavefish
Match: meltf (melanotransferrin [Source:NCBI gene;Acc:103023478])

HSP 1 Score: 261.922 bits (668), Expect = 8.920e-76
Identity = 211/752 (28.06%), Postives = 343/752 (45.61%), Query Frame = 3

Query:   90 VENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGF--FTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNS--DPFAGNAGSMNCLDAARLSGQTSAAFLRGDTL-TNWLANNPNLA-----GFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPF---AGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTS---YYAVAIAKRADKGI-LISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEIC--AAGGQDRCLPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMF-ASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLE 2282
            V  +  ++WC IS  E  KC+ +    + F++ +      C    S  +C   + +  AD  +      Y   +    ++ A E+   ++D      +Y   VV    T  +   L GK +C  G G   GW  P+  +I+S  M++  C    K+  G   F + SC  G+ N       + S+L C  C         C  S  + +    G+  CL    +      AF++  T+  N        A       Y LLCP    DGT   A++   +CN  +  SR ++         + KD   + +      G   S FNLF S+VVF+                      +L+FSD++  F  P    S +  Q++ Q + N + AM   P      ++WCV+S  E  KC +M +A   K L P   CV G S  +CM+ I +  AD +  D   +Y  GK   LVP A E Y +D     YYAVA+ K+++  I   S+ K + +CH+G  + +GW IP+   +E    R    ++  +  E    SC+PG      N  G  P NLC  C   + GQ++C+   ++ Y G +GAFRC+++ +G++AF +H+TV  NTDG N   WA N  S +++LLC   +R +   + +CNL ++P H ++    ++      ++ LL  +Q++F  +S + F MF +S Y  SDL+F DS V++  +  +K+ Y   L + +   +  +E
Sbjct:   20 VSGLSTLRWCTISTQEEAKCSAM---SQAFSSAAIRPTVQCSRAASVAECAQKLTKNEADAFSTSAKDIYEIGKQASFKIAAGES---SSDGEEGTTYYAVAVVKKNNTGININTLKGKKSCHTGLGRTVGWNMPVGYLIDSGKMSVMGC----KVTEGVADFFNASCVPGAVN-------EPSSL-CQLCAGDGSGSHKCEASVNEKYYAYNGAFRCL----VENAGDVAFVKHTTVGENTDGEGEQWAQGLRSADYDLLCP----DGTR-RAVSDYRSCNLARVPSRGIV---------VRKDIDGSTVYTMLREGMQKSGFNLF-SSVVFHGE--------------------NLLFSDSSTKF-IPAG--SEDYIQWMGQRYYNILKAMDCSPADVPQYLQWCVLSQGEQQKCADMAVAFQKKGLTPSIRCVFGKSVDDCMKKIQNKEADAVNFDGGYIYTAGKSFGLVPAAGESYTEDNDGSIYYAVAVVKKSNGNIQRFSDLKGRTSCHTGYERTAGWNIPMATLIEKGLIRPQQCKVAQAAGEFFKGSCVPGA-----NAPGL-PSNLCSQCIGTSTGQNKCVKG-QDLYDGYNGAFRCLVQGSGEIAFVKHSTVFQNTDGNNLDPWAINLNSKEFQLLCSQESRAEVTQYKQCNLARVPSHAVMV---RNDTNPHVIFGLLDKAQQFFGVNSGSDFKMFDSSKYEGSDLIFKDSTVNIVGV-GEKKTYEEWLGQQYLDALVAME 700

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Cavefish
Match: zgc:172271 (melanotransferrin-like [Source:NCBI gene;Acc:103040678])

HSP 1 Score: 254.218 bits (648), Expect = 6.733e-73
Identity = 213/767 (27.77%), Postives = 328/767 (42.76%), Query Frame = 3

Query:  102 EDIKWCVISESEYIKCTKLFTQIRDF---TNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTS----DSRRYC--SNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR----CPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSY----------------YAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQD----RCLPDTREQYYGDSGAFRCMLEN------GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQR-DEMWRLLRYSQEYFASDSNTVFAMFAS-PYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            + ++WC +SE E  KC  L   +        +++    SCV   S+ DC+N +    AD+V LD G  Y AV+ +G+   A E Y    D   +     +V VV   ++     L G  +C +GA    GW  PL  ++   ++         + V+ FF + SC  G++    +         CS+C            +C  S+S+PF  N G+  CL A    G    AF+    L +   +  +    Y+LLC     DGT    L+    CN G+   R ++T+L + +  I + FL      FG        F LF S+V                         DL+FSD T      Q+   ++I Q L  ++   +  +         + ++WC IS  E  KC    L++ S  L     CV   S ++C+  I     D ++LDA   +I GK   LVP+  EYYG+   +                Y VA+ +R+ + +   N   +R+CH      +GWV+P    + T      S +    +SE+  + C+PG  G           NLC++C  G ++    RC  +  E+YYG+ GA RC++ +      GDVAF  H  +  N    N   WA    S D+ELLC DG R     W  CNLG IP + ++T     +P     ++  L  SQE  A+  ++ F MF S  YG SDL+F D+   L  +    ++Y  IL   F  Q E++
Sbjct:   21 KKMRWCTVSEPEQRKCADLAKALVAALPPIAVTAFARLSCVKAYSTADCINKIRANKADLVTLDAGEVYSAVKQFGLMAVAKEIY---IDGGCI----LAVAVVRNSSLLDIRSLKGIRSCHSGARWTAGWSLPLGHLLSRNYLPWAEEQPLSQAVSAFFNA-SCVPGAAAMALSL--------CSQCQGQKSYNPQKNFHCETSHSEPFYNNQGAFRCLKA----GVGDVAFVDHTVLDSIDDSEKDE---YRLLC----TDGTRA-PLSNFRKCNLGRGPGRGVVTRLNNRK--IARKFLTASQMAFGWRRE-RQRFQLFNSSVYGT---------------------NDLLFSDVTDKLTVLQE--DMDISQVLGLDYVALLKGLGHEGSSLEDSVVRWCCISHAEQKKCEQWALSIKSDPL----VCVRASSMSDCIEKIKRDEVDAVSLDATHTFIAGK-CGLVPVVTEYYGEKCEFTQGEEGHFETKDLPSVYGVAVVRRSSRSVYFGNMGGRRSCHGHMYSPAGWVLPAKYTLSTEHNNSASCEPDKVYSEVFWKGCLPGGQG-----------NLCKVCLGGTEEAATKRCSDNHNERYYGNIGALRCLVGDRSGKSYGDVAFIEHHNLESNIKNLNSSGWAEGWLSWDFELLCGDGGRAALTEWKSCNLGAIPPNTVMT-----RPVLIARIYDFLMKSQEATAARPDSEFHMFKSQQYGESDLIFKDATQCL--VHTSHKDYRTILGEEFYSQAESI 710

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Cavefish
Match: tfa (transferrin-a [Source:ZFIN;Acc:ZDB-GENE-980526-35])

HSP 1 Score: 216.468 bits (550), Expect = 7.558e-60
Identity = 203/717 (28.31%), Postives = 313/717 (43.65%), Query Frame = 3

Query:  264 ADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIES---RWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNL-AGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR-----CPFAGIKWCVISDDEMLKCRNMKL-ALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQE---------------YYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGG------QDRCLPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYS---WSKCNLGKIPGHVIVTGGFKSQPQ-RDEMWRLLRYSQEYFAS-DSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSF------ARQVENLE 2282
            AD + LD G  Y A + NY +     E+Y  ++D       Y +V VV KGT      L GK +C  G G + GW  P+  ++      W    +   E + V G+F S SC  G+           S L C  C    D  R  S+ +P+    G+  CL      G    AF++  T+       P +    Y+LLC     D T   +++  + C+     +R+    +VS + P   D    I     P           Q   +F               +S   P  +L+F D+T      Q   + + F YL  ++   I ++ +          IKWC +   E  KC    + ++D         C  G +   C+  I    AD M +D  ++Y  G+   LVP   E               Y  +D SYYAVA+  RAD  +  S+ + K++CH+G G+ +GW +P+ +        ++ D     FS+  ++SC PG   DP +        LC +C   G      + +C   T E YYG SGAFRC++E  GDVAF +HT V ++T G+ P  WA++ +  DY L+CP G   +++    ++KC+L K+P H +VT     +P+ R E+  +L+  Q  F +   N  F MF S  G+ DL+F DS   LK I +D ++Y   L  ++       RQ +NLE
Sbjct:   41 ADAITLDGGDIYQAGLINYDLHPIIAEDYGQDSDTC-----YYAVAVVKKGTEFKFSELKGKKSCHTGLGKSAGWNIPIGTLLSRSRIEWTGPESSPVE-EAVMGYF-SASCVPGAIK--------GSKL-CQLCKG--DCSR--SHKEPYYDYDGAFQCLK----DGAGEVAFVKHLTV-------PAVDKASYELLC----LDDTR-KSIDSYKTCHL----ARVPAHAVVSRKDP---DLAARIFELLKP----------LQDAGLF---------------SSEGYPAKNLIFKDSTKKLV--QLPATTDSFLYLGAQYMAIIRSLKKETSTDSASRAIKWCAVGHAETQKCDAWSINSMDETTGSVRVECQNGKTVDECLSKIMRKEADAMAIDGGQVYSAGR-CGLVPAMVEKYTCKCMIIIAVILLYLSEDPSYYAVAVV-RADSKLTWSSLRGKKSCHTGLGRTAGWNVPMGL--------LHKDTGECDFSKFFSQSCAPG--ADPKS-------KLCALCVGSGKGVGSEEAKCKASTEELYYGYSGAFRCLVEGGGDVAFIKHTIVEEHTGGKGPA-WAKSLKKSDYRLICP-GHPTESFEVSQFAKCHLAKVPAHAVVT-----RPESRAEVVTVLKEQQAKFGTLTPNAPFKMFESEGGK-DLLFKDSTKCLKEI-SDTKSYREFLGAAYLSTMDTLRQCDNLE 659

HSP 2 Score: 117.472 bits (293), Expect = 8.069e-27
Identity = 94/307 (30.62%), Postives = 143/307 (46.58%), Query Frame = 3

Query: 1389 LISDGFADLMTLDAAELYIGGKY-LNLVPIAQEYYGDD--TSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFR---VYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASP-YGRSDLMFSDSAVSLKPIPADKQNYT------MILDRSFARQ 2267
            LI DG AD +TLD  ++Y  G    +L PI  E YG D  T YYAVA+ K+  +    S  K K++CH+G GK++GW IP+   +   +       S  +  +     + SC+PG +             LC++C    +  C    +E YY   GAF+C+ +  G+VAF +H TV         VD A       YELLC D TR    S+  C+L ++P H +V+   K       ++ LL+  Q+           +F+S  Y   +L+F DS   L  +PA   ++       M + RS  ++
Sbjct:   35 LIIDGEADAITLDGGDIYQAGLINYDLHPIIAEDYGQDSDTCYYAVAVVKKGTE-FKFSELKGKKSCHTGLGKSAGWNIPIGTLLSRSRIEWTGPESSPVEEAVMGYFSASCVPGAI---------KGSKLCQLC----KGDCSRSHKEPYYDYDGAFQCLKDGAGEVAFVKHLTV-------PAVDKA------SYELLCLDDTRKSIDSYKTCHLARVPAHAVVS--RKDPDLAARIFELLKPLQDA---------GLFSSEGYPAKNLIFKDSTKKLVQLPATTDSFLYLGAQYMAIIRSLKKE 303

HSP 3 Score: 55.4546 bits (132), Expect = 2.199e-7
Identity = 75/340 (22.06%), Postives = 130/340 (38.24%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA---------VQNYG---MRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKC------TNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWL-ANNPNLAGF-----YQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSN--FNLFQSN 1049
            IKWC +  +E  KC      I      + +    C   ++  +C++ + ++ AD + +D G  Y A         V+ Y    M + AV     + DP+     Y +V VV   +  +   L GK +C  G G   GW  P+  + +    +   C+      + FF S SCA G+         D  +  C+ C        + +++   S  + + G +G+  CL    + G    AF++   +        P  A       Y+L+CP    +   V   +Q   C+  K     +    V TR     + +  +       GTL+ N  F +F+S 
Sbjct:  313 IKWCAVGHAETQKCDAW--SINSMDETTGSVRVECQNGKTVDECLSKIMRKEADAMAIDGGQVYSAGRCGLVPAMVEKYTCKCMIIIAVILLYLSEDPS-----YYAVAVVRADSKLTWSSLRGKKSCHTGLGRTAGWNVPMGLLHK----DTGECD-----FSKFF-SQSCAPGA---------DPKSKLCALCVGSGKGVGSEEAKCKASTEELYYGYSGAFRCL----VEGGGDVAFIKHTIVEEHTGGKGPAWAKSLKKSDYRLICPGHPTESFEV---SQFAKCHLAK-----VPAHAVVTRPESRAEVVTVLKEQQAKFGTLTPNAPFKMFESE 614

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Cavefish
Match: tfa (transferrin-a [Source:ZFIN;Acc:ZDB-GENE-980526-35])

HSP 1 Score: 214.542 bits (545), Expect = 1.656e-59
Identity = 196/694 (28.24%), Postives = 305/694 (43.95%), Query Frame = 3

Query:  264 ADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIES---RWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR-----CPFAGIKWCVISDDEMLKCRNMKL-ALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQD------RCLPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYS---WSKCNLGKIPGHVIVTGGFKSQPQ-RDEMWRLLRYSQEYFAS-DSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            AD + LD G  Y A + NY +     E+Y  ++D       Y +V VV KGT      L GK +C  G G + GW  P+  ++      W    +   E + V G+F S SC  G+           S L C  C    D  R  S+ +P+    G+  CL      G    AF++  T+             Y+LLC     D T   +++  + C+     +R+    +VS + P   D    I     P           Q   +F               +S   P  +L+F D+T      Q   + + F YL  ++   I ++ +          IKWC +   E  KC    + ++D         C  G +   C+  I    AD M +D  ++Y  G+   LVP        D SYYAVA+  RAD  +  S+ + K++CH+G G+ +GW +P+ +        ++ D     FS+  ++SC PG   DP +        LC +C   G+       +C   T E YYG SGAFRC++E  GDVAF +HT V ++T G+ P  WA++ +  DY L+CP G   +++    ++KC+L K+P H +VT     +P+ R E+  +L+  Q  F +   N  F MF S  G+ DL+F DS   LK I +D ++Y   L  ++   ++ L
Sbjct:   24 ADAITLDGGDIYQAGLINYDLHPIIAEDYGQDSDTC-----YYAVAVVKKGTEFKFSELKGKKSCHTGLGKSAGWNIPIGTLLSRSRIEWTGPESSPVE-EAVMGYF-SASCVPGAIK--------GSKL-CQLCKG--DCSR--SHKEPYYDYDGAFQCLK----DGAGEVAFVKHLTVPGE---------HYELLC----LDDTR-KSIDSYKTCHL----ARVPAHAVVSRKDP---DLAARIFELLKP----------LQDAGLF---------------SSEGYPAKNLIFKDSTKKLV--QLPATTDSFLYLGAQYMAIIRSLKKETSTDSASRAIKWCAVGHAETQKCDAWSINSMDETTGSVRVECQNGKTVDECLSKIMRKEADAMAIDGGQVYSAGR-CGLVPAM------DPSYYAVAVV-RADSKLTWSSLRGKKSCHTGLGRTAGWNVPMGL--------LHKDTGECDFSKFFSQSCAPG--ADPKS-------KLCALCVGSGKGVGSEEAKCKASTEELYYGYSGAFRCLVEGGGDVAFIKHTIVEEHTGGKGPA-WAKSLKKSDYRLICP-GHPTESFEVSQFAKCHLAKVPAHAVVT-----RPESRAEVVTVLKEQQAKFGTLTPNAPFKMFESEGGK-DLLFKDSTKCLKEI-SDTKSYREFLGAAYLSTMDTL 611

HSP 2 Score: 116.701 bits (291), Expect = 1.360e-26
Identity = 92/313 (29.39%), Postives = 144/313 (46.01%), Query Frame = 3

Query: 1374 TNCMRLISDGFADLMTLDAAELYIGGKY-LNLVPIAQEYYGDD--TSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFR---VYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASP-YGRSDLMFSDSAVSLKPIPADKQNYT------MILDRSFARQV 2270
            TNC+ +  DG AD +TLD  ++Y  G    +L PI  E YG D  T YYAVA+ K+  +    S  K K++CH+G GK++GW IP+   +   +       S  +  +     + SC+PG +             LC++C    +  C    +E YY   GAF+C+ +  G+VAF +H TV                  + YELLC D TR    S+  C+L ++P H +V+   K       ++ LL+  Q+           +F+S  Y   +L+F DS   L  +PA   ++       M + RS  ++ 
Sbjct:   14 TNCV-IDQDGEADAITLDGGDIYQAGLINYDLHPIIAEDYGQDSDTCYYAVAVVKKGTE-FKFSELKGKKSCHTGLGKSAGWNIPIGTLLSRSRIEWTGPESSPVEEAVMGYFSASCVPGAI---------KGSKLCQLC----KGDCSRSHKEPYYDYDGAFQCLKDGAGEVAFVKHLTV----------------PGEHYELLCLDDTRKSIDSYKTCHLARVPAHAVVS--RKDPDLAARIFELLKPLQDA---------GLFSSEGYPAKNLIFKDSTKKLVQLPATTDSFLYLGAQYMAIIRSLKKET 284

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Cavefish
Match: tfa (transferrin-a [Source:ZFIN;Acc:ZDB-GENE-980526-35])

HSP 1 Score: 215.312 bits (547), Expect = 2.337e-59
Identity = 198/700 (28.29%), Postives = 313/700 (44.71%), Query Frame = 3

Query:  264 ADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIES---RWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNL-AGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGD-TSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHR-----CPFAGIKWCVISDDEMLKCRNMKL-ALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYG----DDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQD------RCLPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYS---WSKCNLGKIPGHVIVTGGFKSQPQ-RDEMWRLLRYSQEYFAS-DSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            AD + LD G  Y A + NY +     E+Y  ++D       Y +V VV KGT      L GK +C  G G + GW  P+  ++      W    +   E + V G+F S SC  G+           S L C  C    D  R  S+ +P+    G+  CL      G    AF++  T+       P +    Y+LLC     D T   +++  + C+     +R+    +VS + P                            ++  ++ AD + +L   G  +S   P  +L+F D+T      Q   + + F YL  ++   I ++ +          IKWC +   E  KC    + ++D         C  G +   C+  I    AD M +D  ++Y  G+   LVP   E Y      D SYYAVA+  RAD  +  S+ + K++CH+G G+ +GW +P+ +        ++ D     FS+  ++SC PG   DP +        LC +C   G+       +C   T E YYG SGAFRC++E  GDVAF +HT V ++T G+ P  WA++ +  DY L+CP G   +++    ++KC+L K+P H +VT     +P+ R E+  +L+  Q  F +   N  F MF S  G+ DL+F DS   LK I +D ++Y   L  ++   ++ L
Sbjct:   61 ADAITLDGGDIYQAGLINYDLHPIIAEDYGQDSDTC-----YYAVAVVKKGTEFKFSELKGKKSCHTGLGKSAGWNIPIGTLLSRSRIEWTGPESSPVE-EAVMGYF-SASCVPGAIK--------GSKL-CQLCKG--DCSR--SHKEPYYDYDGAFQCLK----DGAGEVAFVKHLTV-------PAVDKASYELLC----LDDTR-KSIDSYKTCHL----ARVPAHAVVSRKDP----------------------------DLAAHVDADGMGVLQDAGLFSSEGYPAKNLIFKDSTKKLV--QLPATTDSFLYLGAQYMAIIRSLKKETSTDSASRAIKWCAVGHAETQKCDAWSINSMDETTGSVRVECQNGKTVDECLSKIMRKEADAMAIDGGQVYSAGR-CGLVPAMVEKYTSVHCQDPSYYAVAVV-RADSKLTWSSLRGKKSCHTGLGRTAGWNVPMGL--------LHKDTGECDFSKFFSQSCAPG--ADPKS-------KLCALCVGSGKGVGSEEAKCKASTEELYYGYSGAFRCLVEGGGDVAFIKHTIVEEHTGGKGPA-WAKSLKKSDYRLICP-GHPTESFEVSQFAKCHLAKVPAHAVVT-----RPESRAEVVTVLKEQQAKFGTLTPNAPFKMFESEGGK-DLLFKDSTKCLKEI-SDTKSYREFLGAAYLSTMDTL 662

HSP 2 Score: 114.005 bits (284), Expect = 1.088e-25
Identity = 94/315 (29.84%), Postives = 144/315 (45.71%), Query Frame = 3

Query: 1374 TNCMRLISDGFADLMTLDAAELYIGGKY-LNLVPIAQEYYGDD--TSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFR---VYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVF---AMFASP-YGRSDLMFSDSAVSLKPIPADKQNYT------MILDRSFARQ 2267
            TNC+ +  DG AD +TLD  ++Y  G    +L PI  E YG D  T YYAVA+ K+  +    S  K K++CH+G GK++GW IP+   +   +       S  +  +     + SC+PG +             LC++C    +  C    +E YY   GAF+C+ +  G+VAF +H TV         VD A       YELLC D TR    S+  C+L ++P H +V+   +  P              +  +D   V     +F+S  Y   +L+F DS   L  +PA   ++       M + RS  ++
Sbjct:   51 TNCV-IDQDGEADAITLDGGDIYQAGLINYDLHPIIAEDYGQDSDTCYYAVAVVKKGTE-FKFSELKGKKSCHTGLGKSAGWNIPIGTLLSRSRIEWTGPESSPVEEAVMGYFSASCVPGAI---------KGSKLCQLC----KGDCSRSHKEPYYDYDGAFQCLKDGAGEVAFVKHLTV-------PAVDKA------SYELLCLDDTRKSIDSYKTCHLARVPAHAVVS---RKDPDL----------AAHVDADGMGVLQDAGLFSSEGYPAKNLIFKDSTKKLVQLPATTDSFLYLGAQYMAIIRSLKKE 324

HSP 3 Score: 55.4546 bits (132), Expect = 1.955e-7
Identity = 74/330 (22.42%), Postives = 127/330 (38.48%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYN--FNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKC------TNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWL-ANNPNLAGF-----YQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSN--FNLFQSN 1049
            IKWC +  +E  KC      I      + +    C   ++  +C++ + ++ AD + +D G  Y A    G+    VE Y      DP+     Y +V VV   +  +   L GK +C  G G   GW  P+  + +    +   C+      + FF S SCA G+         D  +  C+ C        + +++   S  + + G +G+  CL    + G    AF++   +        P  A       Y+L+CP    +   V   +Q   C+  K     +    V TR     + +  +       GTL+ N  F +F+S 
Sbjct:  334 IKWCAVGHAETQKCDAW--SINSMDETTGSVRVECQNGKTVDECLSKIMRKEADAMAIDGGQVYSA-GRCGLVPAMVEKYTSVHCQDPS-----YYAVAVVRADSKLTWSSLRGKKSCHTGLGRTAGWNVPMGLLHK----DTGECD-----FSKFF-SQSCAPGA---------DPKSKLCALCVGSGKGVGSEEAKCKASTEELYYGYSGAFRCL----VEGGGDVAFIKHTIVEEHTGGKGPAWAKSLKKSDYRLICPGHPTESFEV---SQFAKCHLAK-----VPAHAVVTRPESRAEVVTVLKEQQAKFGTLTPNAPFKMFESE 624

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010038.1 (pep scaffold:Pmarinus_7.0:GL477069:224754:250935:1 gene:ENSPMAG00000009034.1 transcript:ENSPMAT00000010038.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 297.36 bits (760), Expect = 2.380e-89
Identity = 236/772 (30.57%), Postives = 343/772 (44.43%), Query Frame = 3

Query:   90 VENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQN-YGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIES---RWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCL--DAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATIN-FYFPQDTVSLNIFQYLNQEFQNAITAMHR---------CPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTS---------------YYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEIC--------AAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDS--NTVFAMFASP-YGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            V N  +++WCV S+ E  KC  L   + D   + S Y+  CV   S  +C   +    AD V LD G  Y A +  Y +R  A E+Y  +  PA    +Y +V V   G +S    L GK +C  G G + GW  P+ K++E     W   ++ + E K V+ FF+S SCA GS    F      + L C  C    D++   + ++P+    G+  CL  DA  +      AF++  T+          AG Y+LLC               I         +R         R  I    LN   NYFG NGT  S F LF S+                          +L+F D+T + F  P      +   YL  E+ +A+ ++           CP   ++WC ISD E  KC    L       + E  C+   S   C+ +I +G AD+M+LD  ++Y+ GK   L+P+  EYY DD S               YYAVAI K+ ++ + + +   K  CH+G  + +GW IP  I       ++ S  +    + L    C PG              +LCE C         + G+ +C   + E+Y+G SGAFRCM+E GDVAFA+HTTV +NTDG N   WA+N RS DYELLC DG R    ++  C+L + P H +VT      P ++     LR SQ  +         F++F+S  Y   DL+F DSA  L  + AD  +Y   L   +A+ ++ L
Sbjct:   19 VVNPNEVRWCVTSDKEKKKCMDLAKALGD---LKSQYSLLCVQRDSPNECYETIKSHRADAVTLDGGDIYKAGEAPYLLRPLAGEDYGPDHAPAQGVCYY-AVAVAKAGRVSDLSNLGGKKSCHTGVGKSAGWNLPIGKLLEKGILTWEGPSSGSVE-KAVSNFFSS-SCAPGSKELPFLDKASKAKL-CGLCIGKGDNKCVKNAAEPYYDYGGAFRCLKEDAGDV------AFVKHVTVNEDTTEKAERAG-YELLCGNGGRAPVSDFRRCHIAFVAAHAVVARSSDDIDQRKRSAIL-GLLNEAENYFGVNGTQKSKFELFSSSSYGG---------------------KNLLFKDSTQSLFRLP---ALFDHRSYLGSEYTSALASLSSARKKDATFICP---LRWCCISDGEKNKCDAWDLH------KRELRCLGTHSMEKCIWMIKNGEADVMSLDGGQVYLAGK-CGLIPVMAEYY-DDVSNRGPWLSCLPPPTGKYYAVAIVKKTNRDVSLKDLSGKSICHTGINRTAGWNIP--IGQLVADGKIDSCNIEKGAARLFGPGCTPG----------SREASLCERCIGEEAAAVGSTGKHKCEFSSHERYFGYSGAFRCMVETGDVAFAKHTTVSENTDGANKEAWAKNLRSSDYELLCADGKRAPVSAYKTCHLAQAPSHAVVTRAALKTPVQE----FLRDSQLKYGHSGMDREKFSLFSSERYQGKDLLFKDSAKCLVKVEAD--SYRDFLGAGYAKTMDGL 722

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006102.1 (pep scaffold:Pmarinus_7.0:GL481957:5990:18577:1 gene:ENSPMAG00000005501.1 transcript:ENSPMAT00000006102.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 163.31 bits (412), Expect = 1.650e-45
Identity = 94/264 (35.61%), Postives = 142/264 (53.79%), Query Frame = 3

Query: 1503 SYYAVAIAKRADKGIL-ISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAA--GGQDRCLPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMF-ASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENL 2279
            +Y+AVA+  +A    L     +  R+CH+G G+ +GWVIPV    ++ + +     +   F      SC+PG         G  P +LC++C     G ++C     E+++G +GAFRC+   +GDVAF +HTTV DNTDG NP +WA    S D+ELLCP G R     +  CNL K+P H +VT   +S      ++ +L  +Q+ F SD+ T F MF +S +  +DL+F DS VSL   P  + +Y   L   F   ++ +
Sbjct:   19 TYHAVAVVHKAAPASLTFGTLRGTRSCHTGLGRTAGWVIPVGRLRQSGEVKGEGCDIPKGF---FNASCVPG--------AGNLPPSLCQLCIGNEAGDEKCAASNHERFFGYTGAFRCLASGSGDVAFVKHTTVTDNTDGHNPDEWAHGLLSTDFELLCPSGNRQPVTGFESCNLAKVPPHAVVT---RSSSDPRWIFDVLDAAQKQFGSDNGTRFKMFDSSGFQGTDLLFKDSTVSLF-YPEGRLSYKEWLGGGFLESMQGM 267

HSP 2 Score: 67.0106 bits (162), Expect = 1.940e-12
Identity = 78/297 (26.26%), Postives = 123/297 (41.41%), Query Frame = 3

Query:  384 YTSVVVVIKGTISSPVI--LNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSN--PVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLT-NWLANNPN------LAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGP-NGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAM 1238
            Y +V VV K   +S     L G  +C  G G   GW+ P+ ++ +S  +    C+    I  GFF + SC  G+ N  P    L   +     KC          SN + F G  G+  CL     SG    AF++  T+T N   +NP+      L+  ++LLCP+          +   E+CN  K     ++T+  S    I+ D L+     FG  NGT    F +F S+             G  G         DL+F D+T++ ++P+  +S    ++L   F  ++  M
Sbjct:   20 YHAVAVVHKAAPASLTFGTLRGTRSCHTGLGRTAGWVIPVGRLRQSGEVKGEGCD----IPKGFFNA-SCVPGAGNLPPSLCQLCIGNEAGDEKCA--------ASNHERFFGYTGAFRCL----ASGSGDVAFVKHTTVTDNTDGHNPDEWAHGLLSTDFELLCPSGNR-----QPVTGFESCNLAKVPPHAVVTRSSSDPRWIF-DVLDAAQKQFGSDNGT---RFKMFDSS-------------GFQGT--------DLLFKDSTVSLFYPEGRLSYK--EWLGGGFLESMQGM 267

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Nematostella
Match: EDO32451 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SV02])

HSP 1 Score: 109.768 bits (273), Expect = 3.574e-27
Identity = 76/221 (34.39%), Postives = 106/221 (47.96%), Query Frame = 3

Query: 1263 KWCVISDDEMLKCRNMKLALDSKMLRPE---FYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYG--DDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHDNT 1907
            +WC ISD E+ KC+ +       +   E     CV G   T+CM  I    ADL+TL   ++YI G    L P+  E YG  D   +YAVA+  R+   + I+  K   TCH  A    GW IPV   +     +     +  S  E   +SC+P  + D  N    N   L  +C A     C  D  E+YYG +G++ C++E  G+VAF RHTTV + T
Sbjct:    1 RWCCISDAEVEKCQALAHVASRVVTSNETVNLTCVRGDGVTDCMSRIQRDEADLVTLGEEDIYIAGAKYGLRPVVAEDYGSKDKHIHYAVALV-RSTTTVNITTLKGAITCHPRAEDMIGWKIPVGFLIWKKLMQRKDCDVYNSAGEFFGKSCVP--VFDAAN--NLNNTKLPSLCGACSNPTCPGDESERYYGYNGSYVCLVEGRGEVAFVRHTTVFEYT 216

HSP 2 Score: 71.2478 bits (173), Expect = 6.160e-14
Identity = 63/231 (27.27%), Postives = 95/231 (41.13%), Query Frame = 3

Query:  111 KWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLA----CSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTL 791
            +WC IS++E  KC  L          + T N +CV      DCM+ + +  AD+V L     Y A   YG+R    E+Y      +  +  + +V +V   T  +   L G   C   A    GW  P+  +I  + M    C  +V    G F   SC      PVF+A  + +N      C  C+N +        S+ + G  GS  CL    + G+   AF+R  T+
Sbjct:    1 RWCCISDAEVEKCQALAHVASRVVTSNETVNLTCVRGDGVTDCMSRIQRDEADLVTLGEEDIYIAGAKYGLRPVVAEDYG-----SKDKHIHYAVALVRSTTTVNITTLKGAITCHPRAEDMIGWKIPVGFLIWKKLMQRKDC--DVYNSAGEFFGKSCV-----PVFDAANNLNNTKLPSLCGACSNPTCPG---DESERYYGYNGSYVCL----VEGRGEVAFVRHTTV 212

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Medaka
Match: meltf (melanotransferrin [Source:NCBI gene;Acc:101171320])

HSP 1 Score: 280.796 bits (717), Expect = 1.047e-82
Identity = 217/747 (29.05%), Postives = 352/747 (47.12%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILN---GKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLA--CSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTL-TNWLANNPNLA-----GFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPF---AGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDT---SYYAVAIAKRADKGIL-ISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICA--AGGQDRCLPDTREQYYGDSGAFRCMLE-NGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFAS-PYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLE 2282
            I+WC IS+ E  KC  +    + F+++S   + SCV   +   C+  +  +  D +++     Y A +    ++ A E+ N  T        Y +V VV K  I+S + +N   GK +C  G G   GW  P+  +++  +M++  CN    + +  F + SC  G+     N  GD  +L   C     T   +   S ++ +    G+  CL    +      AF++  T+  N   N P+ A       Y+LLC     DGT    ++Q + C+         + ++    V +  D   +++      G   S F +F S+   +     VL                  FSD T  F   +   S +   ++   + NA+ A    P    A ++WCV+S  E  KC +M +A   K L P+  C+ G S T+CM  I    AD +TLD   +Y  GK   LVP A E Y DDT   SYYAVA+ K++   I  + + + +R+CH+G  + +GW IPV+  ME    R    ++  +  E   +SC+PG      N  G  P NLC++C   + GQ++C    ++ + G  GAFRC+   NGDVAF +HTT+  NTDG +   WA   +S D++LLCP GT+ +   +  CNL ++P H ++    +       ++ LL ++Q YF+SD+ + F MF S  Y  +DL+F DS V +  + A ++ Y   L + +   + ++E
Sbjct:   23 IRWCTISDPEQRKCQAMS---QAFSSVSIRPSLSCVSGPTIEGCVQKLQDKTVDALSMSGPDIYNANKTVSFKIAASESKNGETAS------YYAVAVVKK--INSGININNLAGKRSCHTGKGRTAGWTMPIGYLMDQGYMSVMGCNIPQGVAD--FFNASCIPGA-----NESGDPPSLCQLCKGDNKTGQHKCEMSTNEMYYNYEGAFRCL----VDNAGQVAFIKHTTVGENTDGNGPDWAQKLNSADYELLC----QDGTRA-PVSQWKRCH---------LVRIPFRAVVVNNDITPSVVFSMLKEGLEKSGFKMFSSS---DYGGGAVL------------------FSDLTTTF---ESVTSEDPETWMGNLYNNAMRATDCKPADIPAVLRWCVLSSGEQQKCADMAVAFQQKSLTPKITCIHGDSVTDCMDKIKKREADAVTLDGGYIYTAGKAYGLVPAAAESYTDDTDGASYYAVAVVKKSSTDIRNLDDLRDRRSCHTGFERTAGWNIPVSTLMERGLIRPEQCKIPQAVGEFFKQSCVPGA-----NQPG-FPSNLCDLCVGDSSGQNKC-EKGKDLFDGYDGAFRCLAAGNGDVAFIKHTTIFQNTDGHSSESWASTLQSKDFQLLCPQGTKAEASQYRYCNLARVPSHAVIV---RPDTNIHAVYGLLEHAQAYFSSDTGSGFRMFDSQAYSGTDLIFKDSTVRIIAVGA-RKTYQEWLGQEYIDSLVDME 698

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BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Medaka
Match: tfa (transferrin [Source:NCBI gene;Acc:100144362])

HSP 1 Score: 271.166 bits (692), Expect = 1.513e-79
Identity = 220/730 (30.14%), Postives = 333/730 (45.62%), Query Frame = 3

Query:   99 VEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIES---RWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFY-FPQDTVSLNIFQYLNQEFQNAITAMHRCPFAG-----IKWCVISDDEMLKCRNMKL---ALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYY--GDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEIC-----AAGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQ-RDEMWRLLRYSQEYF-ASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPA 2219
             + +KWCV S+ E+ KC+ L          +++  FSCV   S+ DC+  +    AD + +D G  Y A + NY +     E+Y  +++       Y +V V  KGT      L GK +C  G G + GW  P+  ++     +W  +     E + V+ FF + SC  G++          S L C  C    D  R  S  +P+    G+ NCL      G    AF++  T+ +   +       Y+LLC     D T    ++  + CN     +R+    +V+ + P   + + T LN          NFNLF S                     A  P  +LMF D+T      PQ+T S   F YL  ++ + + ++ +    G     IKWC +   E  KC    +     D+  +     C    S   C++ I    AD M +D  E+Y  GK   LVP   E Y  G  +SYYAVA+ K+ D G+   N K K++CH+G G+ +GW IP+         R+Y       F++     C PG          +   + C +C     A G + +C     EQYYG +GAFRC+ E  GDVAF +HT V +NTDG  P DWAR+ +SDDY+L+CP    V    ++ CNL  +P H +VT     +P+ R ++ R+L+  Q +F AS S+  F +F S  G ++L+F DS   L+ +PA
Sbjct:   21 AQKVKWCVKSDQEFRKCSDL---------AAASPAFSCVKKESTLDCIIAIKAGEADAITVDGGDVYTAGLNNYDLHPIIAEDYGTSSETC-----YYAVAVAKKGTTFGIRDLRGKKSCHTGLGKSAGWNIPIGTLVSMDIIQWAGVEDKPVEEE-VSTFFQA-SCVPGATR--------GSKL-CELCKG--DCSR--SQKEPYYDYNGAFNCL----AEGAGDVAFVKHLTVPDQEKSK------YELLC----RDNTRA-PIDDYKKCNL----ARVPAHAIVTRKDPQLAELIWTSLNSV-------QNFNLFSSE--------------------AYAPSKNLMFKDSTQRLVKLPQNTDS---FLYLGAQYMSIVRSLKKEQTVGTNSNAIKWCAVGHAETAKCDTWSINSVTDDTAAIE----CQNAPSVEECLKKIMRKEADAMAVDGGEVYTAGK-CGLVPAMVEQYDAGQASSYYAVAVVKK-DSGVTWENLKGKKSCHTGIGRTAGWNIPMG--------RIYDQTKDCDFTKFFPSGCAPG---------AEASSSFCTLCKGSGKAVGDEAKCKARPEEQYYGYAGAFRCLAEGAGDVAFIKHTIVGENTDGNGP-DWARSLKSDDYQLICPGKGPVPISEYASCNLAVVPAHAVVT-----RPESRSDVVRVLQVQQTFFGASGSDPSFKLFQSQNG-NNLLFKDSTKCLQEVPA 642

HSP 2 Score: 167.162 bits (422), Expect = 8.130e-43
Identity = 120/360 (33.33%), Postives = 173/360 (48.06%), Query Frame = 3

Query: 1248 PFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGG-KYLNLVPIAQEYYG--DDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVN--IAMETVQFRVYSDQLV-YSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEM-WRLLRYSQEYFASDSNTVFAMFAS-PYGRS-DLMFSDSAVSLKPIPADKQNYTMILDR--SFARQVENLELIG 2291
            P   +KWCV SD E  KC ++  A       P F CV   ST +C+  I  G AD +T+D  ++Y  G    +L PI  E YG   +T YYAVA+AK+      I + + K++CH+G GK++GW IP+   ++M+ +Q+    D+ V    S     SC+PG               LCE+C    +  C    +E YY  +GAF C+ E  GDVAF +H TV D    +             YELLC D TR     + KCNL ++P H IVT   +  PQ  E+ W  L   Q          F +F+S  Y  S +LMF DS   L  +P +  ++  +  +  S  R ++  + +G
Sbjct:   20 PAQKVKWCVKSDQEFRKCSDLAAA------SPAFSCVKKESTLDCIIAIKAGEADAITVDGGDVYTAGLNNYDLHPIIAEDYGTSSETCYYAVAVAKKGTT-FGIRDLRGKKSCHTGLGKSAGWNIPIGTLVSMDIIQWAGVEDKPVEEEVSTFFQASCVPG---------ATRGSKLCELC----KGDCSRSQKEPYYDYNGAFNCLAEGAGDVAFVKHLTVPDQEKSK-------------YELLCRDNTRAPIDDYKKCNLARVPAHAIVT---RKDPQLAELIWTSLNSVQN---------FNLFSSEAYAPSKNLMFKDSTQRLVKLPQNTDSFLYLGAQYMSIVRSLKKEQTVG 334

HSP 3 Score: 68.5514 bits (166), Expect = 1.792e-11
Identity = 96/393 (24.43%), Postives = 153/393 (38.93%), Query Frame = 3

Query:   96 NVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLAC---SKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTL-TNWLANNPNLAGF-----YQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRC 1247
            N   IKWC +  +E  KC      I   T+   T    C    S  +C+  + ++ AD + +D G  Y A +  G+    VE Y+     A     Y +V VV K +  +   L GK +C  G G   GW  P+ ++ +        C+        FF SG      ++  F  L   S  A    +KC    + + Y        G AG+  CL      G    AF++   +  N   N P+ A       YQL+CP     G     +++  +CN     +  ++T+  S R  + +  L     +FG +G+  S F LFQS               Q G+        +L+F D+T          S +  Q+L   +  A+T++ +C
Sbjct:  336 NSNAIKWCAVGHAETAKCDTW--SINSVTD--DTAAIECQNAPSVEECLKKIMRKEADAMAVDGGEVYTAGK-CGLVPAMVEQYD-----AGQASSYYAVAVVKKDSGVTWENLKGKKSCHTGIGRTAGWNIPMGRIYD----QTKDCD-----FTKFFPSGCAPGAEASSSFCTLCKGSGKAVGDEAKCKARPEEQYY--------GYAGAFRCL----AEGAGDVAFIKHTIVGENTDGNGPDWARSLKSDDYQLICP-----GKGPVPISEYASCNLAVVPAHAVVTRPES-RSDVVR-VLQVQQTFFGASGSDPS-FKLFQS---------------QNGN--------NLLFKDSTKCLQEVPAGTSYD--QFLGSGYMEAMTSLRKC 664

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Medaka
Match: tfa (transferrin [Source:NCBI gene;Acc:100144362])

HSP 1 Score: 268.47 bits (685), Expect = 1.701e-78
Identity = 220/737 (29.85%), Postives = 333/737 (45.18%), Query Frame = 3

Query:   99 VEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYA-VQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIES---RWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFY-FPQDTVSLNIFQYLNQEFQNAITAMHRCPFAG-----IKWCVISDDEMLKCRNMKL---ALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYY---------GDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEIC-----AAGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQ-RDEMWRLLRYSQEYF-ASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPA 2219
             + +KWCV S+ E+ KC+ L          +++  FSCV   S+ DC+  +    AD + +D G  Y A + NY +     E+Y  +++       Y +V V  KGT      L GK +C  G G + GW  P+  ++     +W  +     E + V+ FF + SC  G++          S L C  C    D  R  S  +P+    G+ NCL      G    AF++  T+ +   +       Y+LLC     D T    ++  + CN     +R+    +V+ + P   + + T LN          NFNLF S                     A  P  +LMF D+T      PQ+T S   F YL  ++ + + ++ +    G     IKWC +   E  KC    +     D+  +     C    S   C++ I    AD M +D  E+Y  GK   LVP   E Y         G  +SYYAVA+ K+ D G+   N K K++CH+G G+ +GW IP+         R+Y       F++     C PG          +   + C +C     A G + +C     EQYYG +GAFRC+ E  GDVAF +HT V +NTDG  P DWAR+ +SDDY+L+CP    V    ++ CNL  +P H +VT     +P+ R ++ R+L+  Q +F AS S+  F +F S  G ++L+F DS   L+ +PA
Sbjct:   21 AQKVKWCVKSDQEFRKCSDL---------AAASPAFSCVKKESTLDCIIAIKAGEADAITVDGGDVYTAGLNNYDLHPIIAEDYGTSSETC-----YYAVAVAKKGTTFGIRDLRGKKSCHTGLGKSAGWNIPIGTLVSMDIIQWAGVEDKPVEEE-VSTFFQA-SCVPGATR--------GSKL-CELCKG--DCSR--SQKEPYYDYNGAFNCL----AEGAGDVAFVKHLTVPDQEKSK------YELLC----RDNTRA-PIDDYKKCNL----ARVPAHAIVTRKDPQLAELIWTSLNSV-------QNFNLFSSE--------------------AYAPSKNLMFKDSTQRLVKLPQNTDS---FLYLGAQYMSIVRSLKKEQTVGTNSNAIKWCAVGHAETAKCDTWSINSVTDDTAAIE----CQNAPSVEECLKKIMRKEADAMAVDGGEVYTAGK-CGLVPAMVEQYDAELCSSSGGQASSYYAVAVVKK-DSGVTWENLKGKKSCHTGIGRTAGWNIPMG--------RIYDQTKDCDFTKFFPSGCAPG---------AEASSSFCTLCKGSGKAVGDEAKCKARPEEQYYGYAGAFRCLAEGAGDVAFIKHTIVGENTDGNGP-DWARSLKSDDYQLICPGKGPVPISEYASCNLAVVPAHAVVT-----RPESRSDVVRVLQVQQTFFGASGSDPSFKLFQSQNG-NNLLFKDSTKCLQEVPA 649

HSP 2 Score: 167.162 bits (422), Expect = 8.369e-43
Identity = 120/360 (33.33%), Postives = 173/360 (48.06%), Query Frame = 3

Query: 1248 PFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGG-KYLNLVPIAQEYYG--DDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVN--IAMETVQFRVYSDQLV-YSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEM-WRLLRYSQEYFASDSNTVFAMFASP-YGRS-DLMFSDSAVSLKPIPADKQNYTMILDR--SFARQVENLELIG 2291
            P   +KWCV SD E  KC ++  A       P F CV   ST +C+  I  G AD +T+D  ++Y  G    +L PI  E YG   +T YYAVA+AK+      I + + K++CH+G GK++GW IP+   ++M+ +Q+    D+ V    S     SC+PG               LCE+C    +  C    +E YY  +GAF C+ E  GDVAF +H TV D    +             YELLC D TR     + KCNL ++P H IVT   +  PQ  E+ W  L   Q          F +F+S  Y  S +LMF DS   L  +P +  ++  +  +  S  R ++  + +G
Sbjct:   20 PAQKVKWCVKSDQEFRKCSDLAAA------SPAFSCVKKESTLDCIIAIKAGEADAITVDGGDVYTAGLNNYDLHPIIAEDYGTSSETCYYAVAVAKKGTT-FGIRDLRGKKSCHTGLGKSAGWNIPIGTLVSMDIIQWAGVEDKPVEEEVSTFFQASCVPG---------ATRGSKLCELC----KGDCSRSQKEPYYDYNGAFNCLAEGAGDVAFVKHLTVPDQEKSK-------------YELLCRDNTRAPIDDYKKCNLARVPAHAIVT---RKDPQLAELIWTSLNSVQN---------FNLFSSEAYAPSKNLMFKDSTQRLVKLPQNTDSFLYLGAQYMSIVRSLKKEQTVG 334

HSP 3 Score: 67.3958 bits (163), Expect = 4.371e-11
Identity = 95/395 (24.05%), Postives = 153/395 (38.73%), Query Frame = 3

Query:   96 NVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFN--TDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLAC---SKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTL-TNWLANNPNLAGF-----YQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRC 1247
            N   IKWC +  +E  KC      I   T+   T    C    S  +C+  + ++ AD + +D G  Y A +  G+    VE Y+    +        Y +V VV K +  +   L GK +C  G G   GW  P+ ++ +        C+        FF SG      ++  F  L   S  A    +KC    + + Y        G AG+  CL      G    AF++   +  N   N P+ A       YQL+CP     G     +++  +CN     +  ++T+  S R  + +  L     +FG +G+  S F LFQS               Q G+        +L+F D+T          S +  Q+L   +  A+T++ +C
Sbjct:  336 NSNAIKWCAVGHAETAKCDTW--SINSVTD--DTAAIECQNAPSVEECLKKIMRKEADAMAVDGGEVYTAGK-CGLVPAMVEQYDAELCSSSGGQASSYYAVAVVKKDSGVTWENLKGKKSCHTGIGRTAGWNIPMGRIYD----QTKDCD-----FTKFFPSGCAPGAEASSSFCTLCKGSGKAVGDEAKCKARPEEQYY--------GYAGAFRCL----AEGAGDVAFIKHTIVGENTDGNGPDWARSLKSDDYQLICP-----GKGPVPISEYASCNLAVVPAHAVVTRPES-RSDVVR-VLQVQQTFFGASGSDPS-FKLFQS---------------QNGN--------NLLFKDSTKCLQEVPAGTSYD--QFLGSGYMEAMTSLRKC 671

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Medaka
Match: otomp (otolith matrix protein 1 [Source:NCBI gene;Acc:101158493])

HSP 1 Score: 192.586 bits (488), Expect = 4.294e-54
Identity = 115/352 (32.67%), Postives = 180/352 (51.14%), Query Frame = 3

Query: 1260 IKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYG--DDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVY--SFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDR--CLPDTREQYYGDSGAFRCMLEN-GDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASP-YGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIG 2291
            + WCV+SD E  KC ++     +K ++    CV GL+  +CM  I +G AD  ++ A ++Y  G    L   A E Y   D  +YY VA+A+R+   + +     + +CH G     GW +P+   + T Q  V  +Q  +  +       SC+PG+    ++P+G NP NLCE C     DR  C  + RE++YG++GA RC+ EN GDVAF +H TV DN DG+N   WA +   +D +LLCPDGT      + +C+L      V           +  +W+ L   Q  F + +   F++F+S  YG++DL+FSD+   L  +     +YT  L  ++   ++  E  G
Sbjct:   31 VSWCVVSDAEEQKCLDLAGNATAKNVKGTLECVRGLNARDCMNKIKNGTADAASMFADDIYAAGFCHGLDLAAGESYNRVDGINYYVVAMARRSSSDLSLLEMHERSSCHPGMRTTVGWTVPIGYLVNTSQISV-GEQCNFPKAVGNFFGYSCVPGVRDPQHDPSGINPKNLCEACIGDENDRHICANNHRERHYGEAGALRCVAENLGDVAFVKHNTVFDNLDGKNQESWALDLEVEDLKLLCPDGTEAALNEYEQCHLAA----VPANAVVVRVEDKCRVWKYLERLQNVFGNAAEG-FSLFSSADYGQADLLFSDATHHLLRVLG---SYTSWLGPTYTTMLQAFECEG 373

HSP 2 Score: 80.8777 bits (198), Expect = 7.782e-16
Identity = 94/355 (26.48%), Postives = 147/355 (41.41%), Query Frame = 3

Query:  108 IKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNS--DPFAGNAGSMNCL-----DAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDAT 1151
            + WCV+S++E  KC  L        N+  T    CV   ++ DCMN +    AD  ++     Y A   +G+ + A E+YN   D      +Y   +     +  S + ++ +S+C  G  T  GW  P+  ++ +  +++    N  K V  FF   SC  G  +P  +  G N    C  C    + R  C+N+  +   G AG++ C+     D A +   T    L G    +W  +        +LLCP    DGT   ALN+ E C+         +   V  +  ++K +L  + N F   G  +  F+LF        SAD     GQ           DL+FSDAT
Sbjct:   31 VSWCVVSDAEEQKCLDLAGNAT-AKNVKGT--LECVRGLNARDCMNKIKNGTADAASMFADDIYAAGFCHGLDLAAGESYN-RVDGIN---YYVVAMARRSSSDLSLLEMHERSSCHPGMRTTVGWTVPIGYLVNTSQISVGEQCNFPKAVGNFFGY-SCVPGVRDPQHDPSGINPKNLCEACIGDENDRHICANNHRERHYGEAGALRCVAENLGDVAFVKHNTVFDNLDGKNQESWALDLE--VEDLKLLCP----DGTEA-ALNEYEQCHL-AAVPANAVVVRVEDKCRVWK-YLERLQNVF---GNAAEGFSLFS-------SAD----YGQA----------DLLFSDAT 344

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Medaka
Match: ENSORLT00000024771.2 (pep primary_assembly:ASM223467v1:5:629656:641221:1 gene:ENSORLG00000019946.2 transcript:ENSORLT00000024771.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 129.028 bits (323), Expect = 1.386e-31
Identity = 98/328 (29.88%), Postives = 145/328 (44.21%), Query Frame = 3

Query: 1128 DLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYY------GDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQ--------FRVYSDQLVYS--FSELIARSCIPGILGDPYNPTGKNPINLCEICAAG----GQDRCLPDTREQYYGDSGAFR-CMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVT 2048
            DL+F D+T       D   +++ Q L  ++  A+        + ++WC IS  E  KC    L++ S  L     C+   S  +C+  I     D ++LDA   YI GK   LVP+    +          S  AVA+AKR+ + + + N +  R+CHS     +GW++P   A+             R  S   ++   + EL  + C+PG +G           NLC++C  G       RC  +  E+YYG+ GA R      GDVAF  H+             WA+   S D+ELLC DG R     W  CNLG IP + I+T
Sbjct:   41 DLLFRDSTHKLAVVPD--DMDVSQVLGLDYV-ALLKGSSLEDSVMRWCCISHAEQKKCEQWALSIKSDPL----VCIRAASMRDCIEKIKRNEVDAVSLDATHSYIAGK-CGLVPVLMGLFCCCFCPSVLPSLVAVALAKRSSRNVFMGNLEGCRSCHSYLYSPAGWLLPYRHALSPTHNGSSSCDPTRGTSSSHLFQLFYKELFWKGCLPGSVG-----------NLCKVCMGGTGEAATKRCTDNHNERYYGNMGALRYSAFLYGDVAFLEHSG-----------GWAQGWTSSDFELLCGDGRRATLSDWESCNLGVIPPNTIMT 338

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Planmine SMEST
Match: SMESG000027224.1 (SMESG000027224.1)

HSP 1 Score: 1568.13 bits (4059), Expect = 0.000e+0
Identity = 768/773 (99.35%), Postives = 773/773 (100.00%), Query Frame = 3

Query:   27 MFNGKXXXXXXXXXXXXXXXHVENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPKKSGLFYANSSPPTAV 2345
            MFNGKLNFLLPIVLFLSLFLHVENVEDIKWCVISESEYIKCT+LFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPV+LNGKSACFAGAGTAEGWLYPLSKMIE+RWMNITTCNNEVKIVNGFFTSGSCA+GSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGP+KSGLFYANSSPPTAV
Sbjct:    1 MFNGKLNFLLPIVLFLSLFLHVENVEDIKWCVISESEYIKCTQLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVMLNGKSACFAGAGTAEGWLYPLSKMIENRWMNITTCNNEVKIVNGFFTSGSCAVGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPQKSGLFYANSSPPTAV 773

[Close]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Planmine SMEST
Match: SMESG000027225.1 (SMESG000027225.1)

HSP 1 Score: 786.949 bits (2031), Expect = 0.000e+0
Identity = 366/742 (49.33%), Postives = 503/742 (67.79%), Query Frame = 3

Query:   90 VENVEDIKWCVISESEYIKCTKLFTQIRDFTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMRMFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTAEGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALGDNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFLRGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSRMLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADLVLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNAITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTTNCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIAKRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVYSFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYYGDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPDGTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASDSNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVENLELIGGPKKSGLF 2315
            V ++E+IKWC+IS++E  KC ++   I    NIS +Y+ +C+ T S  DCM+ +N R+AD++ LDVGLA Y V NY +R F  ENYNF T+   M+L YT+  VV+K TI+ P  L  K ACF+GAG AEGW++PL++MIE     I  CN+ V+IV+ FF++GSC  G+ + VFN +G+N++ ACS+C++ +D R +CSNSD FAG++G+M CL+      + + AF+RGD +   + N    +  Y+LLC   Q +G +   L  I+ CNWG+PQS++LMT+L S ++  Y++F   +  YFG NGT    F LFQS+  + L+ D  ++L Q+G+    Q  YDLM SD   + YFPQD   +N F  L++ F+ A+  +++C   G+ WC    D M KC  MK AL S  + P F C+ G S  NCM L+S+G+ADLMTLDAAEL+IGGKY++LVPIA E+YGD T YY VA+ K  DKGILISNW   +TCH G G+A GWV+PV IA+ T Q  ++   L+ SF++L++R+CIPGIL   +NP  ++PINLCEIC+ GG D C+  + E  + +SGAF C+LE GD+AF +H TV+DNT+GRN VDWARN++ DD+ELLCPDGTR     W  CN+GK+PG  +VTG FKS  QR+ MW LLR +Q++F++D N+ F+MF SP+ R DLMFSD+AVSLKPIP   Q Y  IL   F RQ E LE +  P  SG +
Sbjct:   15 VTDIEEIKWCLISDAEMAKCIQMQKSI-SLVNISQSYSLTCIQTDSYVDCMDKINHRIADLIMLDVGLASYGVLNYQLRAFGFENYNFETEIPLMKLSYTANAVVVKNTIAHPKDLGQKIACFSGAGRAEGWIFPLTRMIEQTLFEIRKCNSIVEIVSEFFSNGSCIPGNRDSVFNPIGENADNACSQCSSRNDYRGFCSNSDIFAGDSGAMKCLEKNYNESKVAVAFVRGDVILKMIENGDIDSSKYELLCVNDQNEGRFTAPLENIDQCNWGRPQSKVLMTRLSSKQLSSYQNFFELLDQYFGINGTRKDLFELFQSSGEYELTHDFQMMLSQSGEFRPRQLPYDLMVSDTAKSIYFPQDKQIINFFDILDESFKRALDTINQCSIPGVSWCAPDQDVMEKCGRMKTALQSIRVEPSFNCIYGESIPNCMNLVSEGYADLMTLDAAELFIGGKYMDLVPIAIEFYGDSTDYYGVAVVKEMDKGILISNWYNVKTCHGGIGRAVGWVLPVTIALNTQQLVIHDRNLISSFAQLVSRACIPGILDQEFNPDQRHPINLCEICSGGGADLCMASSVEAQFTESGAFVCLLEIGDLAFVKHFTVYDNTEGRNKVDWARNKKLDDFELLCPDGTRQPITKWKNCNIGKVPGTTVVTGSFKSVQQRETMWLLLRLAQDHFSTDGNSFFSMFESPFNRYDLMFSDAAVSLKPIPFINQTYQDILGEHFIRQCEALENLSKPGYSGFY 755

The following BLAST results are available for this feature:

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Human
BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Celegans
BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Fly
BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Zebrafish
BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Xenopus
BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Mouse
BLAST of Family S60 non-peptidase homologue (S60 family) vs. UniProt/SwissProt
BLAST of Family S60 non-peptidase homologue (S60 family) vs. TrEMBL
BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Cavefish
BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Sea Lamprey
BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Yeast
BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Nematostella
BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Medaka
BLAST of Family S60 non-peptidase homologue (S60 family) vs. Planmine SMEST

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MELTF	1.721e-85	29.05	melanotransferrin [Source:HGNC Symbol;Acc:HGNC:703...	[more]
TF	8.035e-83	28.90	transferrin [Source:HGNC Symbol;Acc:HGNC:11740]	[more]
LTF	5.950e-67	26.73	lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720...	[more]
LTF	6.622e-67	26.73	lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720...	[more]
LTF	5.303e-65	26.73	lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720...	[more]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Tsf2	1.060e-100	30.04	gene:FBgn0036299 transcript:FBtr0075966	[more]
Tsf1	1.089e-18	23.69	gene:FBgn0022355 transcript:FBtr0346625	[more]
Tsf1	1.089e-18	23.69	gene:FBgn0022355 transcript:FBtr0074559	[more]
Tsf3	3.293e-10	22.48	gene:FBgn0034094 transcript:FBtr0087130	[more]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
meltf	1.207e-75	27.70	melanotransferrin [Source:ZFIN;Acc:ZDB-GENE-050309...	[more]
zgc:172271	1.723e-68	26.76	zgc:172271 [Source:ZFIN;Acc:ZDB-GENE-080204-110]	[more]
zgc:172271	1.723e-68	26.76	zgc:172271 [Source:ZFIN;Acc:ZDB-GENE-080204-110]	[more]
tfa	5.652e-57	26.24	transferrin-a [Source:ZFIN;Acc:ZDB-GENE-980526-35]	[more]
otomp	5.789e-55	33.05	otolith matrix protein [Source:NCBI gene;Acc:56581...	[more]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MELTF	5.413e-88	28.84	melanotransferrin [Source:NCBI gene;Acc:100158653]	[more]
tf	2.021e-78	28.29	transferrin [Source:NCBI gene;Acc:613079]	[more]
tf	4.605e-78	28.48	transferrin [Source:NCBI gene;Acc:613079]	[more]
tf	1.178e-75	27.72	transferrin [Source:NCBI gene;Acc:613079]	[more]
tf	1.198e-75	28.07	transferrin [Source:NCBI gene;Acc:613079]	[more]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Meltf	1.550e-82	27.98	melanotransferrin [Source:MGI Symbol;Acc:MGI:13534...	[more]
Trf	3.126e-79	29.36	transferrin [Source:MGI Symbol;Acc:MGI:98821]	[more]
Trf	3.126e-79	29.36	transferrin [Source:MGI Symbol;Acc:MGI:98821]	[more]
1300017J02Rik	4.630e-70	26.68	RIKEN cDNA 1300017J02 gene [Source:MGI Symbol;Acc:...	[more]
Ltf	7.254e-66	27.83	lactotransferrin [Source:MGI Symbol;Acc:MGI:96837]	[more]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P08582\|TRFM_HUMAN	8.265e-85	29.05	Melanotransferrin OS=Homo sapiens OX=9606 GN=MELTF...	[more]
sp\|O97490\|TRFM_RABIT	4.253e-84	28.07	Melanotransferrin OS=Oryctolagus cuniculus OX=9986...	[more]
sp\|A5A6I6\|TRFE_PANTR	2.409e-82	29.03	Serotransferrin OS=Pan troglodytes OX=9598 GN=TF P...	[more]
sp\|P02787\|TRFE_HUMAN	3.859e-82	28.90	Serotransferrin OS=Homo sapiens OX=9606 GN=TF PE=1...	[more]
sp\|Q9R0R1\|TRFM_MOUSE	1.085e-81	27.98	Melanotransferrin OS=Mus musculus OX=10090 GN=Melt...	[more]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A3Q0KPX0	0.000e+0	43.22	Family S60 non-peptidase homologue (S60 family) OS...	[more]
G4VHQ7	6.744e-29	43.22	Family S60 non-peptidase homologue (S60 family) OS...	[more]
A0A4Z2D8K1	0.000e+0	43.89	Melanotransferrin OS=Schistosoma japonicum OX=6182...	[more]
A0A4S2MD44	0.000e+0	42.76	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
A0A075AIS8	0.000e+0	42.90	Uncharacterized protein OS=Opisthorchis viverrini ...	[more]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
meltf	8.920e-76	28.06	melanotransferrin [Source:NCBI gene;Acc:103023478]	[more]
zgc:172271	6.733e-73	27.77	melanotransferrin-like [Source:NCBI gene;Acc:10304...	[more]
tfa	7.558e-60	28.31	transferrin-a [Source:ZFIN;Acc:ZDB-GENE-980526-35]	[more]
tfa	1.656e-59	28.24	transferrin-a [Source:ZFIN;Acc:ZDB-GENE-980526-35]	[more]
tfa	2.337e-59	28.29	transferrin-a [Source:ZFIN;Acc:ZDB-GENE-980526-35]	[more]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000010038.1	2.380e-89	30.57	pep scaffold:Pmarinus_7.0:GL477069:224754:250935:1...	[more]
ENSPMAT00000006102.1	1.650e-45	35.61	pep scaffold:Pmarinus_7.0:GL481957:5990:18577:1 ge...	[more]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO32451	3.574e-27	34.39	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
meltf	1.047e-82	29.05	melanotransferrin [Source:NCBI gene;Acc:101171320]	[more]
tfa	1.513e-79	30.14	transferrin [Source:NCBI gene;Acc:100144362]	[more]
tfa	1.701e-78	29.85	transferrin [Source:NCBI gene;Acc:100144362]	[more]
otomp	4.294e-54	32.67	otolith matrix protein 1 [Source:NCBI gene;Acc:101...	[more]
ENSORLT00000024771.2	1.386e-31	29.88	pep primary_assembly:ASM223467v1:5:629656:641221:1...	[more]

BLAST of Family S60 non-peptidase homologue (S60 family) vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2


Match Name	E-value	Identity	Description
SMESG000027224.1	0.000e+0	99.35	SMESG000027224.1	[more]
SMESG000027225.1	0.000e+0	49.33	SMESG000027225.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30007845 ID=SMED30007845|Name=Family S60 non-peptidase homologue (S60 family)|organism=Schmidtea mediterranea sexual|type=transcript|length=2484bp
TTTTATAGTAAGTTTTAACAGTTTAAATGTTCAACGGGAAATTAAATTTT
CTATTACCTATAGTACTGTTTTTGTCATTATTTTTACATGTAGAAAATGT
CGAAGATATAAAATGGTGCGTTATTAGTGAATCGGAATATATTAAATGCA
CTAAATTATTTACTCAAATCCGTGATTTTACTAACATTTCTTCAACATAT
AATTTCTCATGCGTGCTCACCAGAAGTTCATTTGACTGCATGAACCTAGT
CAATCAACGTCTAGCAGATATCGTGAATTTAGATGTTGGATTGGCATATT
ATGCTGTGCAAAATTATGGAATGAGAATGTTTGCTGTAGAAAATTACAAT
TTTAACACTGATCCAGCAACAATGCAGTTATTCTATACATCAGTAGTGGT
TGTAATTAAAGGAACAATTTCATCACCAGTCATATTAAATGGAAAGAGTG
CTTGTTTCGCAGGTGCTGGAACAGCGGAAGGCTGGCTTTACCCTCTGTCG
AAAATGATCGAAAGTCGTTGGATGAATATCACAACCTGTAACAATGAAGT
GAAAATCGTTAATGGATTTTTTACAAGTGGCTCGTGCGCTATCGGCAGTT
CTAATCCGGTTTTCAATGCGCTCGGAGACAACAGCAATCTCGCGTGCAGT
AAATGTACAAATACCAGTGACAGTCGACGTTACTGCTCGAATTCCGATCC
GTTTGCCGGTAACGCCGGATCGATGAATTGCCTGGATGCCGCTCGATTAT
CCGGCCAGACGTCGGCGGCATTCCTACGGGGAGATACTTTGACGAATTGG
CTGGCAAACAATCCGAATTTGGCTGGATTTTATCAATTGCTCTGTCCAAC
CGCTCAAGCCGATGGAACTTATGTGAATGCACTCAACCAGATCGAAGCGT
GCAATTGGGGAAAACCCCAATCACGAATGCTTATGACGCAACTTGTTTCT
ACTCGAGTTCCCATTTATAAGGATTTTCTAAATACCATTCTGAATTATTT
CGGTCCTAATGGAACGCTTTCGTCCAATTTCAATTTATTTCAATCGAATG
TCGTGTTTAACTTGTCGGCGGATTTAGTGTTGTTGCTTGGACAAACCGGA
GACACATCCGCTCCTCAACCGCTTTATGATTTGATGTTCTCCGACGCCAC
TATAAATTTCTATTTCCCCCAAGACACTGTATCACTGAACATTTTCCAAT
ATCTCAATCAAGAGTTCCAAAATGCGATTACAGCCATGCACAGGTGTCCG
TTTGCGGGCATCAAATGGTGCGTTATCAGTGATGATGAAATGCTGAAATG
TCGCAACATGAAATTAGCTCTAGATTCGAAAATGTTACGACCGGAATTCT
ATTGCGTAATGGGATTGTCCACTACAAATTGCATGCGTCTCATCAGTGAT
GGTTTTGCGGATTTGATGACTCTCGATGCCGCGGAACTCTATATTGGCGG
CAAATATTTGAATTTGGTTCCGATAGCTCAAGAGTATTACGGGGACGACA
CGAGTTACTATGCAGTTGCAATCGCCAAACGGGCTGACAAAGGCATCCTC
ATCTCCAACTGGAAATACAAACGTACGTGCCACAGTGGAGCCGGTAAGGC
CAGCGGATGGGTCATTCCAGTGAATATAGCCATGGAGACAGTGCAGTTCC
GAGTGTACAGCGACCAGCTGGTGTACTCATTCAGTGAATTGATCGCCAGG
TCGTGCATCCCAGGGATCCTCGGTGACCCATACAATCCAACCGGGAAAAA
TCCGATAAATCTGTGCGAAATCTGCGCTGCCGGAGGCCAGGACAGATGCC
TACCGGACACTAGAGAACAGTACTACGGTGACAGTGGTGCGTTTCGGTGC
ATGCTGGAAAACGGGGACGTGGCGTTCGCCCGTCACACAACGGTGCACGA
CAACACCGATGGCAGGAATCCCGTGGATTGGGCTCGTAATCGTCGGTCAG
ATGATTATGAATTGCTGTGCCCGGACGGCACTCGTGTCGATACTTACAGC
TGGAGCAAATGCAACCTCGGCAAGATCCCCGGTCACGTCATCGTCACTGG
GGGGTTCAAGAGTCAACCACAGCGGGATGAAATGTGGCGCTTGCTTCGAT
ATTCCCAGGAATACTTTGCATCTGACAGCAATACAGTATTTGCCATGTTC
GCCAGCCCTTATGGACGCAGCGATTTGATGTTCTCTGACAGTGCGGTCAG
CCTCAAACCGATCCCTGCAGATAAACAGAATTACACAATGATTCTCGACC
GCTCATTTGCTAGACAAGTAGAAAACCTGGAATTGATCGGAGGCCCCAAG
AAATCAGGATTATTCTACGCTAATTCCTCTCCACCGACGGCTGTTATTAA
TTTCATTTACTTTATTTTCAGTGTTTCCTTTTCGTTCTTTTTCCTTTTGT
AAAGATAGCAGGCAGATTTACCCCACAAAATGGCTGTGTTGCGTTATGAT
ATCATTTTATTAACGGTTTTGTATTGATAATAAA

protein sequence of SMED30007845-orf-1

>SMED30007845-orf-1 ID=SMED30007845-orf-1|Name=SMED30007845-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=792bp
MFNGKLNFLLPIVLFLSLFLHVENVEDIKWCVISESEYIKCTKLFTQIRD
FTNISSTYNFSCVLTRSSFDCMNLVNQRLADIVNLDVGLAYYAVQNYGMR
MFAVENYNFNTDPATMQLFYTSVVVVIKGTISSPVILNGKSACFAGAGTA
EGWLYPLSKMIESRWMNITTCNNEVKIVNGFFTSGSCAIGSSNPVFNALG
DNSNLACSKCTNTSDSRRYCSNSDPFAGNAGSMNCLDAARLSGQTSAAFL
RGDTLTNWLANNPNLAGFYQLLCPTAQADGTYVNALNQIEACNWGKPQSR
MLMTQLVSTRVPIYKDFLNTILNYFGPNGTLSSNFNLFQSNVVFNLSADL
VLLLGQTGDTSAPQPLYDLMFSDATINFYFPQDTVSLNIFQYLNQEFQNA
ITAMHRCPFAGIKWCVISDDEMLKCRNMKLALDSKMLRPEFYCVMGLSTT
NCMRLISDGFADLMTLDAAELYIGGKYLNLVPIAQEYYGDDTSYYAVAIA
KRADKGILISNWKYKRTCHSGAGKASGWVIPVNIAMETVQFRVYSDQLVY
SFSELIARSCIPGILGDPYNPTGKNPINLCEICAAGGQDRCLPDTREQYY
GDSGAFRCMLENGDVAFARHTTVHDNTDGRNPVDWARNRRSDDYELLCPD
GTRVDTYSWSKCNLGKIPGHVIVTGGFKSQPQRDEMWRLLRYSQEYFASD
SNTVFAMFASPYGRSDLMFSDSAVSLKPIPADKQNYTMILDRSFARQVEN
LELIGGPKKSGLFYANSSPPTAVINFIYFIFSVSFSFFFLL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000018	Category 4 cell
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR001156	Transferrin-like_dom
IPR016357	Transferrin
IPR018195	Transferrin_Fe_BS

Vocabulary: **cellular component**
Term	Definition
GO:0005615	extracellular space
GO:0005576	extracellular region

Vocabulary: **biological process**
Term	Definition
GO:0006810	transport
GO:0006811	ion transport
GO:0055072	iron ion homeostasis

Vocabulary: **molecular function**
Term	Definition
GO:0046872	metal ion binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001156	Transferrin-like domain	PRINTS	PR00422	TRANSFERRIN	coord: 599..620 score: 31.22 coord: 443..461 score: 34.49 coord: 461..475 score: 45.26 coord: 512..535 score: 38.93 coord: 660..678 score: 29.36 coord: 644..658 score: 55.26 coord: 715..733 score: 39.06
IPR001156	Transferrin-like domain	SMART	SM00094	transfer-fin	coord: 28..410 e-value: 2.6E-13 score: 1.3 coord: 412..757 e-value: 2.7E-82 score: 289.4
IPR001156	Transferrin-like domain	PFAM	PF00405	Transferrin	coord: 412..751 e-value: 1.3E-74 score: 251.3 coord: 28..342 e-value: 7.6E-34 score: 117.3
IPR001156	Transferrin-like domain	PROSITE	PS51408	TRANSFERRIN_LIKE_4	coord: 412..753 score: 80.838
IPR001156	Transferrin-like domain	PROSITE	PS51408	TRANSFERRIN_LIKE_4	coord: 28..374 score: 32.085
None	No IPR available	GENE3D	G3DSA:3.40.190.10		coord: 412..751 e-value: 1.6E-100 score: 338.6
None	No IPR available	GENE3D	G3DSA:3.40.190.10		coord: 107..300 e-value: 1.8E-53 score: 184.0
None	No IPR available	GENE3D	G3DSA:3.40.190.10		coord: 28..345 e-value: 1.8E-53 score: 184.0
None	No IPR available	GENE3D	G3DSA:3.40.190.10		coord: 496..669 e-value: 1.6E-100 score: 338.6
None	No IPR available	PANTHER	PTHR11485	TRANSFERRIN	coord: 21..751
None	No IPR available	PANTHER	PTHR11485:SF29	LD22449P	coord: 21..751
None	No IPR available	CDD	cd13529	PBP2_transferrin	coord: 412..738 e-value: 3.83355E-89 score: 281.213
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..24 score: 0.77
None	No IPR available	SUPERFAMILY	SSF53850	Periplasmic binding protein-like II	coord: 411..752
None	No IPR available	SUPERFAMILY	SSF53850	Periplasmic binding protein-like II	coord: 28..403
None	No IPR available	TMHMM	TMhelix		coord: 771..790
IPR016357	Transferrin	PIRSF	PIRSF002549	Transferrin	coord: 5..762 e-value: 6.1E-121 score: 402.4
IPR018195	Transferrin family, iron binding site	PROSITE	PS00205	TRANSFERRIN_LIKE_1	coord: 494..503

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Family S60 non-peptidase homologue (S60 family)

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

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