cAMP-dependent protein kinase type I-alpha regulatory subunit
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30007839 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 22
Homology
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Human
Match: PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9390]) HSP 1 Score: 495.352 bits (1274), Expect = 1.355e-173 Identity = 241/400 (60.25%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E Y+++H I Q+LKDC+V LC+SKP P+ F+RE+F+ LEK+ + L +S + +D H+++ N + KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A E +IQQG++GDNFY++DQGEV++YVN E +SEGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADALE + F+DGE +V QGE G+DFY+I EG A V Q+ S +E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 15 LKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSN-SQSDSHDEEVSPTPPNPVV--------------------------------KARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 381
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Human
Match: PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9390]) HSP 1 Score: 495.352 bits (1274), Expect = 1.355e-173 Identity = 241/400 (60.25%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E Y+++H I Q+LKDC+V LC+SKP P+ F+RE+F+ LEK+ + L +S + +D H+++ N + KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A E +IQQG++GDNFY++DQGEV++YVN E +SEGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADALE + F+DGE +V QGE G+DFY+I EG A V Q+ S +E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 15 LKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSN-SQSDSHDEEVSPTPPNPVV--------------------------------KARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 381
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Human
Match: PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9390]) HSP 1 Score: 495.352 bits (1274), Expect = 1.355e-173 Identity = 241/400 (60.25%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E Y+++H I Q+LKDC+V LC+SKP P+ F+RE+F+ LEK+ + L +S + +D H+++ N + KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A E +IQQG++GDNFY++DQGEV++YVN E +SEGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADALE + F+DGE +V QGE G+DFY+I EG A V Q+ S +E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 15 LKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSN-SQSDSHDEEVSPTPPNPVV--------------------------------KARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 381
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Human
Match: PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9390]) HSP 1 Score: 495.352 bits (1274), Expect = 1.355e-173 Identity = 241/400 (60.25%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E Y+++H I Q+LKDC+V LC+SKP P+ F+RE+F+ LEK+ + L +S + +D H+++ N + KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A E +IQQG++GDNFY++DQGEV++YVN E +SEGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADALE + F+DGE +V QGE G+DFY+I EG A V Q+ S +E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 15 LKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSN-SQSDSHDEEVSPTPPNPVV--------------------------------KARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 381
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Human
Match: PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9390]) HSP 1 Score: 495.352 bits (1274), Expect = 1.355e-173 Identity = 241/400 (60.25%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E Y+++H I Q+LKDC+V LC+SKP P+ F+RE+F+ LEK+ + L +S + +D H+++ N + KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A E +IQQG++GDNFY++DQGEV++YVN E +SEGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADALE + F+DGE +V QGE G+DFY+I EG A V Q+ S +E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 15 LKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSN-SQSDSHDEEVSPTPPNPVV--------------------------------KARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 381
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Celegans
Match: kin-2 (cAMP-dependent protein kinase regulatory subunit [Source:UniProtKB/Swiss-Prot;Acc:P30625]) HSP 1 Score: 374.4 bits (960), Expect = 1.005e-126 Identity = 192/398 (48.24%), Postives = 259/398 (65.08%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISI 1260
L + + Y++ HNI QL+K+ +V LC+ KP++PV F++++F+ L +Q ++ N ++ + + K++ RR +S E EDD Y K V+PKD T +L A+ KN+LF+HL+E E+ ++DAMFP+ K A E +I+QG++GDNFY+ID+G V++YVN E T++EGGSFGELALIYGTPRAATV A TDVKLW IDR +YRRILMGS KKRK+Y EFLS+V IL +LD+WE+ VADALE +F+ G +VV+QG+ G++F++I+EG A V QK SD VG L SDYFGEIALLL+RPRAATV A LKC+KLDR RFERVMG EILKR++ YNSY+ +
Sbjct: 10 LAQCQAYVQRHNIQQLVKEAIVVLCIHKPDNPVLFLKDHFEKLNEQRAQEGGNPDAADDDDIIVE------------------------------------------PPKRSGGRRTGISAEPIKEDDT-EYKKVVIPKDDATRRSLESAMRKNLLFAHLEEDEQKTMYDAMFPVEKSAGETIIEQGEEGDNFYVIDKGTVDVYVNHEYVLTINEGGSFGELALIYGTPRAATVIAKTDVKLWAIDRLTYRRILMGSVTKKRKMYDEFLSKVQILADLDQWERANVADALERCDFEPGTHVVEQGQPGDEFFIILEGEANVLQKRSDDAPFDVVGHLGMSDYFGEIALLLDRPRAATVVAKTHLKCIKLDRNRFERVMGPVREILKRDVSNYNSYVKL 364
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Celegans
Match: kin-2 (cAMP-dependent protein kinase regulatory subunit [Source:UniProtKB/Swiss-Prot;Acc:P30625]) HSP 1 Score: 374.785 bits (961), Expect = 1.208e-126 Identity = 192/398 (48.24%), Postives = 259/398 (65.08%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISI 1260
L + + Y++ HNI QL+K+ +V LC+ KP++PV F++++F+ L +Q ++ N ++ + + K++ RR +S E EDD Y K V+PKD T +L A+ KN+LF+HL+E E+ ++DAMFP+ K A E +I+QG++GDNFY+ID+G V++YVN E T++EGGSFGELALIYGTPRAATV A TDVKLW IDR +YRRILMGS KKRK+Y EFLS+V IL +LD+WE+ VADALE +F+ G +VV+QG+ G++F++I+EG A V QK SD VG L SDYFGEIALLL+RPRAATV A LKC+KLDR RFERVMG EILKR++ YNSY+ +
Sbjct: 20 LAQCQAYVQRHNIQQLVKEAIVVLCIHKPDNPVLFLKDHFEKLNEQRAQEGGNPDAADDDDIIVE------------------------------------------PPKRSGGRRTGISAEPIKEDDT-EYKKVVIPKDDATRRSLESAMRKNLLFAHLEEDEQKTMYDAMFPVEKSAGETIIEQGEEGDNFYVIDKGTVDVYVNHEYVLTINEGGSFGELALIYGTPRAATVIAKTDVKLWAIDRLTYRRILMGSVTKKRKMYDEFLSKVQILADLDQWERANVADALERCDFEPGTHVVEQGQPGDEFFIILEGEANVLQKRSDDAPFDVVGHLGMSDYFGEIALLLDRPRAATVVAKTHLKCIKLDRNRFERVMGPVREILKRDVSNYNSYVKL 374
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Celegans
Match: kin-2 (cAMP-dependent protein kinase regulatory subunit [Source:UniProtKB/Swiss-Prot;Acc:P30625]) HSP 1 Score: 350.132 bits (897), Expect = 1.141e-117 Identity = 172/289 (59.52%), Postives = 217/289 (75.09%), Query Frame = 1
Query: 394 KKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISI 1260
K++ RR +S E EDD Y K V+PKD T +L A+ KN+LF+HL+E E+ ++DAMFP+ K A E +I+QG++GDNFY+ID+G V++YVN E T++EGGSFGELALIYGTPRAATV A TDVKLW IDR +YRRILMGS KKRK+Y EFLS+V IL +LD+WE+ VADALE +F+ G +VV+QG+ G++F++I+EG A V QK SD VG L SDYFGEIALLL+RPRAATV A LKC+KLDR RFERVMG EILKR++ YNSY+ +
Sbjct: 45 KRSGGRRTGISAEPIKEDDT-EYKKVVIPKDDATRRSLESAMRKNLLFAHLEEDEQKTMYDAMFPVEKSAGETIIEQGEEGDNFYVIDKGTVDVYVNHEYVLTINEGGSFGELALIYGTPRAATVIAKTDVKLWAIDRLTYRRILMGSVTKKRKMYDEFLSKVQILADLDQWERANVADALERCDFEPGTHVVEQGQPGDEFFIILEGEANVLQKRSDDAPFDVVGHLGMSDYFGEIALLLDRPRAATVVAKTHLKCIKLDRNRFERVMGPVREILKRDVSNYNSYVKL 332
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Celegans
Match: egl-4 (cGMP-dependent protein kinase egl-4 [Source:UniProtKB/Swiss-Prot;Acc:O76360]) HSP 1 Score: 131.339 bits (329), Expect = 3.640e-32 Identity = 74/249 (29.72%), Postives = 136/249 (54.62%), Query Frame = 1
Query: 490 KTMSA---LSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGP-LKCVKLDRKRFERVMGSCAEILK 1224
KT+ A + A++KN L +++ ++ + M+ + +A + +IQ+G+ GD +++ +GE+++ L + G GELA++Y R A+V+A TDV+LW +DR ++ I +++ FL++V I + L + +AD ++ +D G Y+++QGE G+ F++I G KV Q+ E+ L D+FGE ALL R A + A P ++ + LDR+ F +++G + K
Sbjct: 153 KTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQWVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGTVMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGETEPREIRVLNQGDFFGERALLGEEVRTANIIAQAPGVEVLTLDRESFGKLIGDLESLKK 401
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Celegans
Match: egl-4 (cGMP-dependent protein kinase egl-4 [Source:UniProtKB/Swiss-Prot;Acc:O76360]) HSP 1 Score: 131.339 bits (329), Expect = 3.640e-32 Identity = 74/249 (29.72%), Postives = 136/249 (54.62%), Query Frame = 1
Query: 490 KTMSA---LSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGP-LKCVKLDRKRFERVMGSCAEILK 1224
KT+ A + A++KN L +++ ++ + M+ + +A + +IQ+G+ GD +++ +GE+++ L + G GELA++Y R A+V+A TDV+LW +DR ++ I +++ FL++V I + L + +AD ++ +D G Y+++QGE G+ F++I G KV Q+ E+ L D+FGE ALL R A + A P ++ + LDR+ F +++G + K
Sbjct: 153 KTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQWVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGTVMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGETEPREIRVLNQGDFFGERALLGEEVRTANIIAQAPGVEVLTLDRESFGKLIGDLESLKK 401
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Fly
Match: Pka-R1 (gene:FBgn0259243 transcript:FBtr0300535) HSP 1 Score: 492.656 bits (1267), Expect = 8.048e-173 Identity = 244/400 (61.00%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E YI+ H I ++LKDC+V+LC+ +P +PV F+R+YFQ LE++ +K L+ S I+ +D + L+ + A RRG +S E TE+DA +YVKKVVPKDYKTM+ALSKAI KNVLF+HLDE ERSDIFDAMFP++ A E +IQQGD+GDNFY+ID GEV+++VN EL T+SEGGSFGELALIYGTPRAATVRA TDVKLWGIDRDSYRRILMGSTI+KRK+Y+EFLSRV ILE LDKWE+LTVAD+LE+ +FDDGE +VKQG G+DFY+I+EG A V Q+ S+ E+ EVG L +SDYFGEIALLL+RPRAATV A GPLKCVKLDR RFERV+G CA+ILKRNI +YNS++S++V
Sbjct: 14 LRECEHYIQTHGIQRVLKDCIVQLCVCRPENPVQFLRQYFQKLEREQVK--LDASRQVISPDDCED-----------LSPMPQTAA------------------------PPVRRRGGISAEPVTEEDATNYVKKVVPKDYKTMNALSKAIAKNVLFAHLDESERSDIFDAMFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEGEDPAEVGRLGSSDYFGEIALLLDRPRAATVVARGPLKCVKLDRARFERVLGPCADILKRNITQYNSFVSLSV 376
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Fly
Match: Pka-R1 (gene:FBgn0259243 transcript:FBtr0300534) HSP 1 Score: 492.656 bits (1267), Expect = 8.048e-173 Identity = 244/400 (61.00%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E YI+ H I ++LKDC+V+LC+ +P +PV F+R+YFQ LE++ +K L+ S I+ +D + L+ + A RRG +S E TE+DA +YVKKVVPKDYKTM+ALSKAI KNVLF+HLDE ERSDIFDAMFP++ A E +IQQGD+GDNFY+ID GEV+++VN EL T+SEGGSFGELALIYGTPRAATVRA TDVKLWGIDRDSYRRILMGSTI+KRK+Y+EFLSRV ILE LDKWE+LTVAD+LE+ +FDDGE +VKQG G+DFY+I+EG A V Q+ S+ E+ EVG L +SDYFGEIALLL+RPRAATV A GPLKCVKLDR RFERV+G CA+ILKRNI +YNS++S++V
Sbjct: 14 LRECEHYIQTHGIQRVLKDCIVQLCVCRPENPVQFLRQYFQKLEREQVK--LDASRQVISPDDCED-----------LSPMPQTAA------------------------PPVRRRGGISAEPVTEEDATNYVKKVVPKDYKTMNALSKAIAKNVLFAHLDESERSDIFDAMFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEGEDPAEVGRLGSSDYFGEIALLLDRPRAATVVARGPLKCVKLDRARFERVLGPCADILKRNITQYNSFVSLSV 376
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Fly
Match: Pka-R1 (gene:FBgn0259243 transcript:FBtr0300528) HSP 1 Score: 492.656 bits (1267), Expect = 8.048e-173 Identity = 244/400 (61.00%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E YI+ H I ++LKDC+V+LC+ +P +PV F+R+YFQ LE++ +K L+ S I+ +D + L+ + A RRG +S E TE+DA +YVKKVVPKDYKTM+ALSKAI KNVLF+HLDE ERSDIFDAMFP++ A E +IQQGD+GDNFY+ID GEV+++VN EL T+SEGGSFGELALIYGTPRAATVRA TDVKLWGIDRDSYRRILMGSTI+KRK+Y+EFLSRV ILE LDKWE+LTVAD+LE+ +FDDGE +VKQG G+DFY+I+EG A V Q+ S+ E+ EVG L +SDYFGEIALLL+RPRAATV A GPLKCVKLDR RFERV+G CA+ILKRNI +YNS++S++V
Sbjct: 14 LRECEHYIQTHGIQRVLKDCIVQLCVCRPENPVQFLRQYFQKLEREQVK--LDASRQVISPDDCED-----------LSPMPQTAA------------------------PPVRRRGGISAEPVTEEDATNYVKKVVPKDYKTMNALSKAIAKNVLFAHLDESERSDIFDAMFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEGEDPAEVGRLGSSDYFGEIALLLDRPRAATVVARGPLKCVKLDRARFERVLGPCADILKRNITQYNSFVSLSV 376
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Fly
Match: Pka-R1 (gene:FBgn0259243 transcript:FBtr0300530) HSP 1 Score: 492.656 bits (1267), Expect = 8.048e-173 Identity = 244/400 (61.00%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E YI+ H I ++LKDC+V+LC+ +P +PV F+R+YFQ LE++ +K L+ S I+ +D + L+ + A RRG +S E TE+DA +YVKKVVPKDYKTM+ALSKAI KNVLF+HLDE ERSDIFDAMFP++ A E +IQQGD+GDNFY+ID GEV+++VN EL T+SEGGSFGELALIYGTPRAATVRA TDVKLWGIDRDSYRRILMGSTI+KRK+Y+EFLSRV ILE LDKWE+LTVAD+LE+ +FDDGE +VKQG G+DFY+I+EG A V Q+ S+ E+ EVG L +SDYFGEIALLL+RPRAATV A GPLKCVKLDR RFERV+G CA+ILKRNI +YNS++S++V
Sbjct: 14 LRECEHYIQTHGIQRVLKDCIVQLCVCRPENPVQFLRQYFQKLEREQVK--LDASRQVISPDDCED-----------LSPMPQTAA------------------------PPVRRRGGISAEPVTEEDATNYVKKVVPKDYKTMNALSKAIAKNVLFAHLDESERSDIFDAMFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEGEDPAEVGRLGSSDYFGEIALLLDRPRAATVVARGPLKCVKLDRARFERVLGPCADILKRNITQYNSFVSLSV 376
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Fly
Match: Pka-R1 (gene:FBgn0259243 transcript:FBtr0299892) HSP 1 Score: 492.656 bits (1267), Expect = 8.048e-173 Identity = 244/400 (61.00%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E YI+ H I ++LKDC+V+LC+ +P +PV F+R+YFQ LE++ +K L+ S I+ +D + L+ + A RRG +S E TE+DA +YVKKVVPKDYKTM+ALSKAI KNVLF+HLDE ERSDIFDAMFP++ A E +IQQGD+GDNFY+ID GEV+++VN EL T+SEGGSFGELALIYGTPRAATVRA TDVKLWGIDRDSYRRILMGSTI+KRK+Y+EFLSRV ILE LDKWE+LTVAD+LE+ +FDDGE +VKQG G+DFY+I+EG A V Q+ S+ E+ EVG L +SDYFGEIALLL+RPRAATV A GPLKCVKLDR RFERV+G CA+ILKRNI +YNS++S++V
Sbjct: 14 LRECEHYIQTHGIQRVLKDCIVQLCVCRPENPVQFLRQYFQKLEREQVK--LDASRQVISPDDCED-----------LSPMPQTAA------------------------PPVRRRGGISAEPVTEEDATNYVKKVVPKDYKTMNALSKAIAKNVLFAHLDESERSDIFDAMFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEGEDPAEVGRLGSSDYFGEIALLLDRPRAATVVARGPLKCVKLDRARFERVLGPCADILKRNITQYNSFVSLSV 376
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Zebrafish
Match: prkar1ab (protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b [Source:ZFIN;Acc:ZDB-GENE-050417-238]) HSP 1 Score: 502.286 bits (1292), Expect = 1.399e-176 Identity = 245/400 (61.25%), Postives = 311/400 (77.75%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E Y++ HN+ QLLKDC+V+LC S+P+ P++F+REYF+ LEK+ K LN+ ++ S +DS ED ++ + VV K R RRGA+S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A EI+IQQGD+GDNFY+IDQGE+++YVN+E ++ EGGSFGELALIYGTPRAATVRA T+VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+D + +V QGE G++F++I+EG A V Q+ S++E +EVG L SDYFGEIALL+NRPRAATV A GPLKCVKLDR RFERV+G C++ILKRNI++YNS++S++V
Sbjct: 14 LRECEVYVQKHNVQQLLKDCIVQLCTSRPDRPMAFLREYFERLEKEESKQLLNQQKAS--------------SRSDSR---EDEVS-----------PPMNPVV------KGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVTYIAGEIVIQQGDEGDNFYVIDQGEMDVYVNNEWATSIGEGGSFGELALIYGTPRAATVRAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDSQKIVVQGEPGDEFFIILEGCAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 379
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Zebrafish
Match: prkar1b (protein kinase, cAMP-dependent, regulatory, type I, beta [Source:ZFIN;Acc:ZDB-GENE-060929-580]) HSP 1 Score: 494.967 bits (1273), Expect = 1.206e-173 Identity = 242/400 (60.50%), Postives = 299/400 (74.75%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E +++ HNI Q+LK+C+V LC++KP P+ F+RE+F+ LEK+ K + +S + +D H D+ S KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A E +IQQGD+GDNFY+IDQGEV++YVN E ++ EGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DGE +V QGE G+DF++I EG A V Q+ SD+E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 14 LKGCEVFVQKHNIQQILKECIVNLCIAKPERPMKFLREHFEKLEKEECKQIMARQKSN-SQSDSH--------------------------------DDEVSPPPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGDEGDNFYVIDQGEVDVYVNGEWVTSIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 380
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Zebrafish
Match: prkar1b (protein kinase, cAMP-dependent, regulatory, type I, beta [Source:ZFIN;Acc:ZDB-GENE-060929-580]) HSP 1 Score: 494.967 bits (1273), Expect = 1.206e-173 Identity = 242/400 (60.50%), Postives = 299/400 (74.75%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E +++ HNI Q+LK+C+V LC++KP P+ F+RE+F+ LEK+ K + +S + +D H D+ S KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A E +IQQGD+GDNFY+IDQGEV++YVN E ++ EGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DGE +V QGE G+DF++I EG A V Q+ SD+E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 14 LKGCEVFVQKHNIQQILKECIVNLCIAKPERPMKFLREHFEKLEKEECKQIMARQKSN-SQSDSH--------------------------------DDEVSPPPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGDEGDNFYVIDQGEVDVYVNGEWVTSIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 380
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Zebrafish
Match: prkar1aa (protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a [Source:ZFIN;Acc:ZDB-GENE-050116-2]) HSP 1 Score: 484.567 bits (1246), Expect = 1.740e-169 Identity = 232/400 (58.00%), Postives = 302/400 (75.50%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E Y++ HNI QLLKDC+V+LC ++P P++++R+YF+ LE + K + S+ + ++ + S N + K R RRGA+S EVYTE+DA SYV+KV+PKDYKTM+AL+KAIEKNVLF+HLD+ ERSDIFDAMF + A E +IQQGD+GDNFY+IDQGE+++YVN+E ++ EGGSFGELALIYGTPRAATVRA T+VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE++ F+DG+ +V QG+ G++F++I+EG A V Q+ S++E +EVG L SDYFGEIALL+NRPRAATV A GPLKCVKLDR RFERV+G C++ILKRNI++YNS++S++V
Sbjct: 14 LRECERYVQKHNIQQLLKDCIVQLCTARPERPMAYLRDYFEKLELEEAKQMV--SQQKSSSRSDSREDEVSPPMNPVV--------------------------------KGRRRRGAISAEVYTEEDATSYVRKVIPKDYKTMAALAKAIEKNVLFAHLDDNERSDIFDAMFSVTYIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWVTSIGEGGSFGELALIYGTPRAATVRAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALETVQFEDGQKIVVQGQPGDEFFIILEGSAAVLQRRSENEEFVEVGRLAPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 379
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Zebrafish
Match: prkar1b (protein kinase, cAMP-dependent, regulatory, type I, beta [Source:ZFIN;Acc:ZDB-GENE-060929-580]) HSP 1 Score: 338.961 bits (868), Expect = 7.708e-115 Identity = 158/214 (73.83%), Postives = 187/214 (87.38%), Query Frame = 1
Query: 625 GDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
GD+GDNFY+IDQGEV++YVN E ++ EGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DGE +V QGE G+DF++I EG A V Q+ SD+E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 4 GDEGDNFYVIDQGEVDVYVNGEWVTSIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 217 HSP 2 Score: 63.1586 bits (152), Expect = 5.956e-11 Identity = 47/152 (30.92%), Postives = 74/152 (48.68%), Query Frame = 1
Query: 448 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGS------FGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMG-STIKKRKL--YQEFLS 876
D SY + ++ + + + K + LD+ ER + DA+ P+ + E ++ QG+ GD+F+II +G + N E G FGE+AL+ PRAATV A +K +DR + R+L S I KR + Y F+S
Sbjct: 63 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFIS 214
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Xenopus
Match: adarb1 (adenosine deaminase, RNA-specific, B1 [Source:Xenbase;Acc:XB-GENE-954085]) HSP 1 Score: 496.508 bits (1277), Expect = 5.116e-174 Identity = 242/400 (60.50%), Postives = 301/400 (75.25%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E Y++ +NI QLLK+C+V LC++KP+ P+ F+RE+F+ LEK+ K L + +S + +D H+ + N + KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP++ A E +IQQGD+GDNFY+IDQGE ++YVN E + EGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DGE +V QGE G+DF++I EG A V Q+ SD+E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 14 LKGCEVYVQKYNIQQLLKECIVNLCIAKPDRPMKFLREHFEKLEKEECKQILAQQKSN-SQSDSHDDEISPPPPNPVV--------------------------------KARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVNHIAGETVIQQGDEGDNFYVIDQGEADVYVNGEWVTNIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 380
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Xenopus
Match: adarb1 (adenosine deaminase, RNA-specific, B1 [Source:Xenbase;Acc:XB-GENE-954085]) HSP 1 Score: 496.893 bits (1278), Expect = 1.067e-173 Identity = 244/400 (61.00%), Postives = 304/400 (76.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E Y++ +NI QLLK+C+V LC++KP+ P+ F+RE+F+ LEK+ K L + +S ++ SH+D ++ + VV KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP++ A E +IQQGD+GDNFY+IDQGE ++YVN E + EGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DGE +V QGE G+DF++I EG A V Q+ SD+E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 48 LKGCEVYVQKYNIQQLLKECIVNLCIAKPDRPMKFLREHFEKLEKEECKQILAQQKSNSQSD----------SHDDEISPPPPN-----------------PVV------KARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVNHIAGETVIQQGDEGDNFYVIDQGEADVYVNGEWVTNIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 414
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Xenopus
Match: adarb1 (adenosine deaminase, RNA-specific, B1 [Source:Xenbase;Acc:XB-GENE-954085]) HSP 1 Score: 454.907 bits (1169), Expect = 3.158e-158 Identity = 213/290 (73.45%), Postives = 251/290 (86.55%), Query Frame = 1
Query: 397 KARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP++ A E +IQQGD+GDNFY+IDQGE ++YVN E + EGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DGE +V QGE G+DF++I EG A V Q+ SD+E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 52 KARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVNHIAGETVIQQGDEGDNFYVIDQGEADVYVNGEWVTNIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 341
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Xenopus
Match: prkar1a (protein kinase cAMP-dependent type I regulatory subunit alpha [Source:NCBI gene;Acc:594933]) HSP 1 Score: 352.829 bits (904), Expect = 9.021e-119 Identity = 167/261 (63.98%), Postives = 211/261 (80.84%), Query Frame = 1
Query: 397 KARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDR 1179
K R RRGA+S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLF+HLD+ ERSDIFDAMF + A E +IQQGD+GDNFY++DQGE+++YVN++ ++ EGGSFGELALIYGTPRAATV+A T+VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DG+ +V QGE G++F++I+EG A V Q+ S++E +EVG L SDYFGE Q L+C+ + R
Sbjct: 53 KGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFAHLDDNERSDIFDAMFSVTYIAGETVIQQGDEGDNFYVVDQGEMDVYVNNDWMTSIGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEF------------QCATLLRCIGVRR 301 HSP 2 Score: 62.7734 bits (151), Expect = 3.352e-10 Identity = 46/153 (30.07%), Postives = 79/153 (51.63%), Query Frame = 1
Query: 802 DRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERV-MGSCAEILKRNIKKYNSYIS 1257
D SY R ++ K + + + + LD E+ + DA+ S+ + GE V++QG+ G++FY++ +G V+ +++ +GE FGE+AL+ PRAATV+A +K +DR + R+ MGS R K Y ++S
Sbjct: 70 DAASYVRKVIPKDYKTMAALAKAIEKNVLFAHLDDNERSDIFDAMFSVTYIAGETVIQQGDEGDNFYVVDQGEMDVY---VNNDWMTSIGE---GGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTL----RKRKMYEEFLS 212
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Xenopus
Match: prkar1a (protein kinase cAMP-dependent type I regulatory subunit alpha [Source:NCBI gene;Acc:594933]) HSP 1 Score: 353.984 bits (907), Expect = 1.426e-118 Identity = 167/261 (63.98%), Postives = 211/261 (80.84%), Query Frame = 1
Query: 397 KARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDR 1179
K R RRGA+S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLF+HLD+ ERSDIFDAMF + A E +IQQGD+GDNFY++DQGE+++YVN++ ++ EGGSFGELALIYGTPRAATV+A T+VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DG+ +V QGE G++F++I+EG A V Q+ S++E +EVG L SDYFGE Q L+C+ + R
Sbjct: 100 KGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFAHLDDNERSDIFDAMFSVTYIAGETVIQQGDEGDNFYVVDQGEMDVYVNNDWMTSIGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEF------------QCATLLRCIGVRR 348 HSP 2 Score: 63.1586 bits (152), Expect = 3.308e-10 Identity = 46/153 (30.07%), Postives = 79/153 (51.63%), Query Frame = 1
Query: 802 DRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERV-MGSCAEILKRNIKKYNSYIS 1257
D SY R ++ K + + + + LD E+ + DA+ S+ + GE V++QG+ G++FY++ +G V+ +++ +GE FGE+AL+ PRAATV+A +K +DR + R+ MGS R K Y ++S
Sbjct: 117 DAASYVRKVIPKDYKTMAALAKAIEKNVLFAHLDDNERSDIFDAMFSVTYIAGETVIQQGDEGDNFYVVDQGEMDVY---VNNDWMTSIGE---GGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTL----RKRKMYEEFLS 259
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Mouse
Match: Prkar1b (protein kinase, cAMP dependent regulatory, type I beta [Source:MGI Symbol;Acc:MGI:97759]) HSP 1 Score: 489.96 bits (1260), Expect = 1.222e-171 Identity = 243/400 (60.75%), Postives = 297/400 (74.25%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E Y++ H I Q+LK+C+V LC++KP+ P+ F+RE+F+ LEK+ + L +S N +C S DE S KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLFSHLD+ ERSDIFDAMFP+ E +IQQG++GDNFY+IDQGEV++YVN E +SEGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADALE + F+DGE +V QGE G+DFY+I EG A V Q+ S +E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 15 LKGCEMYVQKHGIQQVLKECIVHLCVAKPDRPLRFLREHFEKLEKEENRQILARQKS--------NSQCDSH-------------------------DEEISPTPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFSHLDDNERSDIFDAMFPVTHIGGETVIQQGNEGDNFYVIDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 381
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Mouse
Match: Prkar1b (protein kinase, cAMP dependent regulatory, type I beta [Source:MGI Symbol;Acc:MGI:97759]) HSP 1 Score: 489.96 bits (1260), Expect = 1.222e-171 Identity = 243/400 (60.75%), Postives = 297/400 (74.25%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E Y++ H I Q+LK+C+V LC++KP+ P+ F+RE+F+ LEK+ + L +S N +C S DE S KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLFSHLD+ ERSDIFDAMFP+ E +IQQG++GDNFY+IDQGEV++YVN E +SEGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADALE + F+DGE +V QGE G+DFY+I EG A V Q+ S +E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 15 LKGCEMYVQKHGIQQVLKECIVHLCVAKPDRPLRFLREHFEKLEKEENRQILARQKS--------NSQCDSH-------------------------DEEISPTPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFSHLDDNERSDIFDAMFPVTHIGGETVIQQGNEGDNFYVIDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 381
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Mouse
Match: Prkar1a (protein kinase, cAMP dependent regulatory, type I, alpha [Source:MGI Symbol;Acc:MGI:104878]) HSP 1 Score: 487.649 bits (1254), Expect = 1.037e-170 Identity = 238/400 (59.50%), Postives = 303/400 (75.75%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E Y++ HNI LLKD +V+LC ++P P++F+REYF+ LEK+ + ++ I + S D ++ + VV K R RRGA+S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A E +IQQGD+GDNFY+IDQGE+++YVN+E +V EGGSFGELALIYGTPRAATV+A T+VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DG+ +V QGE G++F++I+EG A V Q+ S++E +EVG L SDYFGEIALL+NRPRAATV A GPLKCVKLDR RFERV+G C++ILKRNI++YNS++S++V
Sbjct: 15 LRECELYVQKHNIQALLKDSIVQLCTTRPERPMAFLREYFERLEKEEARQIQCLQKTGIRTD----------SREDEISPPPPN-----------------PVV------KGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 381
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Mouse
Match: Prkar1a (protein kinase, cAMP dependent regulatory, type I, alpha [Source:MGI Symbol;Acc:MGI:104878]) HSP 1 Score: 487.649 bits (1254), Expect = 1.037e-170 Identity = 238/400 (59.50%), Postives = 303/400 (75.75%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E Y++ HNI LLKD +V+LC ++P P++F+REYF+ LEK+ + ++ I + S D ++ + VV K R RRGA+S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A E +IQQGD+GDNFY+IDQGE+++YVN+E +V EGGSFGELALIYGTPRAATV+A T+VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DG+ +V QGE G++F++I+EG A V Q+ S++E +EVG L SDYFGEIALL+NRPRAATV A GPLKCVKLDR RFERV+G C++ILKRNI++YNS++S++V
Sbjct: 15 LRECELYVQKHNIQALLKDSIVQLCTTRPERPMAFLREYFERLEKEEARQIQCLQKTGIRTD----------SREDEISPPPPN-----------------PVV------KGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 381
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Mouse
Match: Prkar1b (protein kinase, cAMP dependent regulatory, type I beta [Source:MGI Symbol;Acc:MGI:97759]) HSP 1 Score: 399.053 bits (1024), Expect = 1.007e-137 Identity = 187/257 (72.76%), Postives = 221/257 (85.99%), Query Frame = 1
Query: 496 MSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
M+AL+KAI KNVLFSHLD+ ERSDIFDAMFP+ E +IQQG++GDNFY+IDQGEV++YVN E +SEGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADALE + F+DGE +V QGE G+DFY+I EG A V Q+ S +E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 1 MTALAKAISKNVLFSHLDDNERSDIFDAMFPVTHIGGETVIQQGNEGDNFYVIDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 257 HSP 2 Score: 63.929 bits (154), Expect = 5.716e-11 Identity = 47/152 (30.92%), Postives = 74/152 (48.68%), Query Frame = 1
Query: 448 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGS------FGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMG-STIKKRKL--YQEFLS 876
D SY + ++ + + + K + L++ ER + DA+ P+ + E ++ QG+ GD+FYII +G + N E G FGE+AL+ PRAATV A +K +DR + R+L S I KR + Y F+S
Sbjct: 103 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFIS 254
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. UniProt/SwissProt
Match: sp|P31319|KAPR_APLCA (cAMP-dependent protein kinase regulatory subunit OS=Aplysia californica OX=6500 PE=2 SV=2) HSP 1 Score: 498.819 bits (1283), Expect = 2.523e-174 Identity = 238/400 (59.50%), Postives = 305/400 (76.25%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+E E Y++ HNI QLLK+C+V+L ++KP SP++F+R++F LEK+ + ++S + ++ + + ++N+ R+RRGAVS EVY E+DAA YVKKVVPKDYKTM+ALSKAI KNVLFSHLD+ ERSDIFDAMFP+H+ A E++IQQGD+GDNFY+IDQGEV++YVN+ ++ EGGSFGELALIYGTPRAATV+A TDVKLWGIDRDSYRRILMGSTI+KRK+Y++FLS+V ILE LDKWE+LTVADALE + F+D E +V+QGE GEDF++I+EG A V Q+ S++E +EVG L SDYFGEIALLL+RPRAATV A GPLKCVKLDR RFERV+G C++ILKRNI +YNS++S++V
Sbjct: 11 LKECEAYVQKHNIQQLLKECIVQLVVNKPESPLAFLRDHFDRLEKEQVAKEKSKSATPPSDEKEEDMSSTPPQMHPAMNK--------------------------------RMRRGAVSAEVYREEDAAQYVKKVVPKDYKTMAALSKAISKNVLFSHLDDNERSDIFDAMFPVHRHAGEVIIQQGDEGDNFYVIDQGEVDVYVNNVHVTSIGEGGSFGELALIYGTPRAATVKAKTDVKLWGIDRDSYRRILMGSTIRKRKIYEDFLSKVSILENLDKWERLTVADALEPVQFEDKEEIVRQGEPGEDFFIILEGSAAVLQRRSENEEPVEVGRLGPSDYFGEIALLLDRPRAATVVARGPLKCVKLDRARFERVLGPCSDILKRNISQYNSFVSLSV 378
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. UniProt/SwissProt
Match: sp|P31321|KAP1_HUMAN (cAMP-dependent protein kinase type I-beta regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1B PE=1 SV=4) HSP 1 Score: 495.352 bits (1274), Expect = 6.507e-173 Identity = 241/400 (60.25%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E Y+++H I Q+LKDC+V LC+SKP P+ F+RE+F+ LEK+ + L +S + +D H+++ N + KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A E +IQQG++GDNFY++DQGEV++YVN E +SEGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADALE + F+DGE +V QGE G+DFY+I EG A V Q+ S +E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 15 LKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSN-SQSDSHDEEVSPTPPNPVV--------------------------------KARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 381
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. UniProt/SwissProt
Match: sp|Q5ZM91|KAP0_CHICK (cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Gallus gallus OX=9031 GN=PRKAR1A PE=2 SV=1) HSP 1 Score: 494.967 bits (1273), Expect = 9.772e-173 Identity = 240/396 (60.61%), Postives = 302/396 (76.26%), Query Frame = 1
Query: 79 EEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
E Y++ HNI QLLKDC+V+LC +P+ P+ F+REYF+ LEK+ K LN+ +S S +DS DE S K R RRGA+S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLF+HLD+ ERSDIFDAMFP+ A E +IQQGD+GDNFY++DQGE+++YVN+E +V EGGSFGELALIYGTPRAATV+A T+VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DG+ +V QGE G++F++I+EG A V Q+ S++E +EVG L SDYFGEIALL+NRPRAATV A G LKCVKLDR RFERV+G C++ILKRNI++YNS++S++V
Sbjct: 19 ELYVQKHNIQQLLKDCIVQLCTVRPDRPMGFLREYFERLEKEETKQLLNQQKSG--------------SRSDSRE------------------DEISPPPPMNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFAHLDDNERSDIFDAMFPVTYIAGETVIQQGDEGDNFYVVDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGTAAVLQRRSENEEFVEVGRLAPSDYFGEIALLMNRPRAATVVARGLLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 382
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. UniProt/SwissProt
Match: sp|P16905|KAPR1_DROME (cAMP-dependent protein kinase type I regulatory subunit OS=Drosophila melanogaster OX=7227 GN=Pka-R1 PE=2 SV=2) HSP 1 Score: 492.656 bits (1267), Expect = 8.067e-172 Identity = 244/400 (61.00%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E YI+ H I ++LKDC+V+LC+ +P +PV F+R+YFQ LE++ +K L+ S I+ +D + L+ + A RRG +S E TE+DA +YVKKVVPKDYKTM+ALSKAI KNVLF+HLDE ERSDIFDAMFP++ A E +IQQGD+GDNFY+ID GEV+++VN EL T+SEGGSFGELALIYGTPRAATVRA TDVKLWGIDRDSYRRILMGSTI+KRK+Y+EFLSRV ILE LDKWE+LTVAD+LE+ +FDDGE +VKQG G+DFY+I+EG A V Q+ S+ E+ EVG L +SDYFGEIALLL+RPRAATV A GPLKCVKLDR RFERV+G CA+ILKRNI +YNS++S++V
Sbjct: 14 LRECEHYIQTHGIQRVLKDCIVQLCVCRPENPVQFLRQYFQKLEREQVK--LDASRQVISPDDCED-----------LSPMPQTAA------------------------PPVRRRGGISAEPVTEEDATNYVKKVVPKDYKTMNALSKAIAKNVLFAHLDESERSDIFDAMFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEGEDPAEVGRLGSSDYFGEIALLLDRPRAATVVARGPLKCVKLDRARFERVLGPCADILKRNITQYNSFVSLSV 376
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. UniProt/SwissProt
Match: sp|P09456|KAP0_RAT (cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Rattus norvegicus OX=10116 GN=Prkar1a PE=1 SV=2) HSP 1 Score: 490.73 bits (1262), Expect = 4.440e-171 Identity = 239/400 (59.75%), Postives = 304/400 (76.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E Y++ HNI LLKD +V+LC ++P P++F+REYF+ LEK+ + + +S I + S D ++ + VV K R RRGA+S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A E +IQQGD+GDNFY+IDQGE+++YVN+E +V EGGSFGELALIYGTPRAATV+A T+VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DG+ +V QGE G++F++I+EG A V Q+ S++E +EVG L SDYFGEIALL+NRPRAATV A GPLKCVKLDR RFERV+G C++ILKRNI++YNS++S++V
Sbjct: 15 LRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEARQIQSLQKSGIRTD----------SREDEISPPPPN-----------------PVV------KGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 381
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. TrEMBL
Match: A0A1I8J2X2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig004255g1 PE=4 SV=1) HSP 1 Score: 523.087 bits (1346), Expect = 0.000e+0 Identity = 257/406 (63.30%), Postives = 312/406 (76.85%), Query Frame = 1
Query: 49 KMNASYLEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
+ + ++L+E+E YIK HNI Q LK+C+V LC+++P++P ++IR++F LEK+ + SF+ A D+ + ++ K R RRGAVSGEVYTE+DAASYVKKVVPKDYKTM+ALSKAI KNVLFSHLD+ ERSDIFDAMFPLH+ A E++I+QG +GDNFYI+DQGEV+IYVN E TV EGGSFGELALIYGTPRAATV+A TDVKLWGIDRDSYRRILMGSTI+KRK+Y+EFL +VPILE LDKWE+LTVADALE + F+D E VV+QGE G+DF++I+EGVA V QKPS++E +EVG+L SDYFGEIALLL+RPRAATV A GPLKCVKLDRKRFERVMG C++ILKRNI KYNSYIS+TV
Sbjct: 4 RTDEAHLKEVENYIKSHNIQQSLKECIVHLCVARPDNPFAYIRDFFDKLEKERT-----------------GQAPASFAALPQAEPPA----------PAAEEDDSAGLMMPQSAPKKRGRRGAVSGEVYTEEDAASYVKKVVPKDYKTMAALSKAIAKNVLFSHLDDNERSDIFDAMFPLHRNATEVIIEQGAEGDNFYILDQGEVDIYVNGEHVGTVGEGGSFGELALIYGTPRAATVKAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLGKVPILENLDKWERLTVADALEPVAFEDNEVVVRQGEPGDDFFIILEGVAAVLQKPSENEEAVEVGKLGPSDYFGEIALLLDRPRAATVTAKGPLKCVKLDRKRFERVMGPCSDILKRNISKYNSYISLTV 382
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. TrEMBL
Match: A0A1I8JK81 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 520.776 bits (1340), Expect = 1.639e-180 Identity = 257/406 (63.30%), Postives = 310/406 (76.35%), Query Frame = 1
Query: 49 KMNASYLEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
+ + ++L+E+E YIK HNI Q LK+C+V LC+++P++P ++IR++F LEK SF+ A D+ + ++ K R RRGAVSGEVYTE+DAASYVKKVVPKDYKTM+ALSKAI KNVLFSHLD+ ERSDIFDAMFPLH+ A E++I+QG +GDNFYI+DQGEV+IYVN E TV EGGSFGELALIYGTPRAATV+A TDVKLWGIDRDSYRRILMGSTI+KRK+Y+EFL +VPILE LDKWE+LTVADALE + F+D E VV+QGE G+DF++I+EGVA V QKPS++E +EVG+L SDYFGEIALLL+RPRAATV A GPLKCVKLDRKRFERVMG C++ILKRNI KYNSYIS+TV
Sbjct: 4 RTDEAHLKEVENYIKSHNIQQSLKECIVHLCVARPDNPFAYIRDFFDKLEKA----------------------PASFAALPQAEPPA----------PAAEEDDSAGLMMPQSAPKKRGRRGAVSGEVYTEEDAASYVKKVVPKDYKTMAALSKAIAKNVLFSHLDDNERSDIFDAMFPLHRNATEVIIEQGAEGDNFYILDQGEVDIYVNGEHVGTVGEGGSFGELALIYGTPRAATVKAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLGKVPILENLDKWERLTVADALEPVAFEDNEVVVRQGEPGDDFFIILEGVAAVLQKPSENEEAVEVGKLGPSDYFGEIALLLDRPRAATVTAKGPLKCVKLDRKRFERVMGPCSDILKRNISKYNSYISLTV 377
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. TrEMBL
Match: A0A1I8HGN2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 515.768 bits (1327), Expect = 7.250e-178 Identity = 251/410 (61.22%), Postives = 314/410 (76.59%), Query Frame = 1
Query: 61 SYLEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSA--------KDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
++L+++E Y++ H + ++LK+C+V+LC +P++P +I+EYF ++K + L + T + + + S A + + G +VD S + + +K R RRGAVSGEVYTE+DAASYVKKVVPKDYKTM ALSKAI KNVLFSHLDE ERSDIFDAMFPLH+ A+E++I+QG +GDNFYI+DQGEV+I+VN TVSEGGSFGELALIYGTPRAATV+A T+VKLWGIDRDSYRRILMGSTI+KRK+Y+EFLS+VPILE LD WE+LTVADALE++ F+D + VV+QGE GEDF++I+EGVA V QKPS+++ +EVG L SDYFGEIALLL+RPRAATV A GPLKCVKLDRKRFERVMG C +ILKRNI KYNSYI +TV
Sbjct: 8 AHLKDVESYLEKHGVQKVLKECIVQLCTVQPDNPFEYIKEYFDKVDKDRI---LMPDQFATTGAGSESLASSALATGTSRALASTAGAALPMPGTEGDVDYDSETMLPPMPAAAAAPQSQKQRTRRGAVSGEVYTEEDAASYVKKVVPKDYKTMGALSKAITKNVLFSHLDENERSDIFDAMFPLHRNADEVIIEQGAEGDNFYILDQGEVDIFVNGNYISTVSEGGSFGELALIYGTPRAATVKAKTEVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVPILENLDLWERLTVADALENVTFEDQKIVVRQGEAGEDFFIILEGVASVLQKPSENDEAVEVGRLGPSDYFGEIALLLDRPRAATVIARGPLKCVKLDRKRFERVMGPCGDILKRNIAKYNSYILLTV 414
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. TrEMBL
Match: A0A1I8H3F0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig016081g3 PE=4 SV=1) HSP 1 Score: 514.227 bits (1323), Expect = 2.571e-177 Identity = 250/410 (60.98%), Postives = 315/410 (76.83%), Query Frame = 1
Query: 61 SYLEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVC--------SAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
++L+++E Y++ H + ++LK+C+V+LC +P++P +I+EYF ++K + L + T + + + S + + G +VD S + + + +K R RRGAVSGEVYTE+DAASYVKKVVPKDYKTM ALSKAI KNVLFSHLDE ERSDIFDAMFPLH+ A+E++I+QG +GDNFYI+DQGEV+I+VN + TVSEGGSFGELALIYGTPRAATV+A T+VKLWGIDRDSYRRILMGSTI+KRK+Y+EFLS+VPILE LD WE+LTVADALE++ F+D + VV+QGE GEDF++I+EGVA V QKPS+++ +EVG L SDYFGEIALLL+RPRAATV A GPLKCVKLDRKRFERVMG C +ILKRNI KYNSYI +TV
Sbjct: 8 AHLKDVEGYLEKHGVQKVLKECIVQLCTVQPDNPFEYIKEYFDKVDKDRI---LMPDQFATTGAGSESLASSALATGTSRALASTAGTALPMPGTEGDVDYDSETMLPPMPAAAAAPQSQKQRTRRGAVSGEVYTEEDAASYVKKVVPKDYKTMGALSKAITKNVLFSHLDENERSDIFDAMFPLHRNADEVIIEQGAEGDNFYILDQGEVDIFVNGDYISTVSEGGSFGELALIYGTPRAATVKAKTEVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVPILENLDLWERLTVADALENVTFEDQKIVVRQGEAGEDFFIILEGVASVLQKPSENDEAVEVGRLGPSDYFGEIALLLDRPRAATVIARGPLKCVKLDRKRFERVMGPCGDILKRNIAKYNSYILLTV 414
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. TrEMBL
Match: A0A1S8WHE0 (Cyclic nucleotide-binding domain protein OS=Opisthorchis viverrini OX=6198 GN=X801_10517 PE=4 SV=1) HSP 1 Score: 514.998 bits (1325), Expect = 1.728e-176 Identity = 265/480 (55.21%), Postives = 331/480 (68.96%), Query Frame = 1
Query: 61 SYLEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLE--------------------KQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNEL------EDHMAGMEIIG----------------LACNVDEYS----------------------SVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEV--------------EIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
S++ +E+YIK +NIH+LL+D +V LCL +P++PV ++REYF+ LE K N+ +L+ ++ + N+ SF+ +D++N L E + +G + NVD S S++ + R RRGAVSGEVYTE+DAASYVKKVVPKDYKTM+ALSKAI KNVLFSHLDE ERSDIFDAMFP+H+ +++IQQGD+GDNFYI+DQGEV +I+VN+E + TV EGGSFGELALIYGTPRAATV+A T+VKLWGIDRDSYRRILMGSTI++RK+YQEFL RVPIL+ LDKWE+LTVADALE + F+DGE VV+QGE G+DF++I EG AKV QKPS+S +EVG+L SDYFGEIALLL+RPRAATV A GPL+CVKLDRKRFERVMG C++ILKRNI KYNSYIS++V
Sbjct: 5 SFINGVEDYIKRYNIHELLRDSIVNLCLYRPSNPVGYLREYFEKLETKSIPCGADSMENGGVTSSQKSNIPRHLSTTKKPYSTNESGPLPPVSFNQSDNVNHLNCNHKEEPRSHDADFVGANNFLSGTFLNETVPQIPYNVDPNGGASESGVGEAGSSGGNESFTTFSPSGSSEVTRRRSRRGAVSGEVYTEEDAASYVKKVVPKDYKTMTALSKAIAKNVLFSHLDETERSDIFDAMFPVHRNPGDVIIQQGDEGDNFYIVDQGEVDPIHVVHFMVCVIAQIFVNNEYSSTVGEGGSFGELALIYGTPRAATVKAKTEVKLWGIDRDSYRRILMGSTIRRRKMYQEFLCRVPILDNLDKWERLTVADALEPVRFEDGEVVVRQGEPGDDFFIITEGTAKVLQKPSESVEPVEVGKLRPSDYFGEIALLLDRPRAATVVAQGPLRCVKLDRKRFERVMGPCSDILKRNIAKYNSYISLSV 484
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Cavefish
Match: prkar1ab (cAMP-dependent protein kinase type I-alpha regulatory subunit [Source:NCBI gene;Acc:103038385]) HSP 1 Score: 498.049 bits (1281), Expect = 7.184e-175 Identity = 244/400 (61.00%), Postives = 308/400 (77.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E Y++ HNI QLLKDC+V+LC S+P P+ F+REYF+ LEK+ K L++ ++ S +DS ED ++ + VV K R RRGA+S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A EI+IQQGD+GDNFY+IDQGE+++YVN+E ++ EGGSFGELALIYGTPRAATVRA T+ KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+D + +V QGE G++F++I+EG A V Q+ S++E +EVG L SDYFGEIALL+NRPRAATV A GPLKCVKLDR RFERV+G C++ILKRNI++YNS++S++V
Sbjct: 14 LRECELYVQKHNIQQLLKDCIVQLCTSRPERPMVFLREYFERLEKEEAKQLLSQQKTS--------------SRSDSR---EDEVS-----------PPMNPVV------KGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVTYIAGEIVIQQGDEGDNFYVIDQGEMDVYVNNEWATSIGEGGSFGELALIYGTPRAATVRAKTNAKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDSQKIVVQGEPGDEFFIILEGCAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 379
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Cavefish
Match: prkar1aa (cAMP-dependent protein kinase type I-alpha regulatory subunit [Source:NCBI gene;Acc:103047413]) HSP 1 Score: 486.878 bits (1252), Expect = 1.459e-170 Identity = 234/400 (58.50%), Postives = 305/400 (76.25%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E+Y++ H+I QLLKDC+V+LC S+P P++F+R+YF+ LEK+ K + + +S ++ + S N + K R RRGA+S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLF+HLD+ ERSDIFDAMFP++ A E +IQQGD+GDNFY+IDQGE+++YVN+ ++ EGGSFGELALIYGTPRAATVRA T+VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE++ F+DG+ +V QG+ G++F++I+EG A V Q+ S++E +EVG L SDYFGEIALL+NRPRAATV A PLKCVKLDR RFERV+G C++ILKRNI++YNS++S++V
Sbjct: 14 LRECEQYVQKHSIQQLLKDCIVQLCTSRPERPMAFLRDYFERLEKEEAKQMVGQQKSSSRSD--SREDEISPPMNPVV--------------------------------KGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFAHLDDNERSDIFDAMFPVNYIAGETVIQQGDEGDNFYVIDQGEMDVYVNNAWVTSIGEGGSFGELALIYGTPRAATVRAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALETVQFEDGQKIVVQGQPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARSPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 379
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Cavefish
Match: prkar1b (protein kinase cAMP-dependent type I regulatory subunit beta [Source:NCBI gene;Acc:111191378]) HSP 1 Score: 484.567 bits (1246), Expect = 1.622e-169 Identity = 238/400 (59.50%), Postives = 296/400 (74.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E +++ HN+ Q+LK+C+V LC++KP P+ F+RE+F+ LEK+ K L +S ++ ++ S KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A E +IQQGD+GDNFY+IDQGEV++YVN E + EGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADALE + F+DGE +V QGE G+DF++I EG A V Q+ SD+E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 16 LKGCEIFVQKHNVQQILKECIVNLCIAKPERPMKFLREHFEKLEKEECKQILARQKSSSQSDSHDDE---------------------------------VSPPPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGDEGDNFYVIDQGEVDVYVNGEWVTGIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 382
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Cavefish
Match: prkar2aa (protein kinase, cAMP-dependent, regulatory, type II, alpha A [Source:ZFIN;Acc:ZDB-GENE-030131-1007]) HSP 1 Score: 210.69 bits (535), Expect = 6.275e-63 Identity = 108/266 (40.60%), Postives = 170/266 (63.91%), Query Frame = 1
Query: 472 VVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVN-DELNCTVSE---GGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKP---SDSEN--EIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKY 1242
V PK + L +A + +LF LD+++ S++ DAMF + + E +I QGDDGDNFY+I++G +I V D + C V + GSFGELAL+Y TPRAAT+ A + LWG+DR ++RR+++ + KKR++Y+ F+ VP+L+ L+ E++ + D L F DGE ++ QG++ + FY++ G K+ K +D ++ E+E+ YFGE+AL+ N+PRA + A G +KC+ +D + FER++G C EI+KRNI Y
Sbjct: 102 VHPKTDEQRCRLQEACKDILLFKALDQEQFSEVLDAMFEVIVQPQEHVIDQGDDGDNFYVIERGVYDIVVQKDGVGCCVGQYDNKGSFGELALMYNTPRAATIIAKQEGALWGLDRATFRRLIVKNNAKKRRMYECFIESVPLLKSLEISERMKIVDVLGVKIFHDGERIIMQGDMADCFYIVESGEVKIMMKSKTKADRQDNAEVEITRCTRGQYFGELALVTNKPRAGSAYAVGDIKCLVIDVQAFERLLGPCKEIMKRNIAHY 367
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Cavefish
Match: si:ch211-272n13.7 (protein kinase cAMP-dependent type II regulatory subunit beta [Source:NCBI gene;Acc:103029925]) HSP 1 Score: 209.149 bits (531), Expect = 5.076e-62 Identity = 130/391 (33.25%), Postives = 212/391 (54.22%), Query Frame = 1
Query: 103 IHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYT--EDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYV-NDELNCTVSE---GGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQK----PSDS-ENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKY 1242
+ +LL+ V++ ++P + F +YF L+ E+E N++ + ++N +E+ M I DE A +RR +V E + EDD + PK + L +A + +LF +LD+++ S + DAMF + E +I Q DDGDNFY+I++G +I V +D + TV GSFGELAL+Y TPRAAT+ A + LW +DR ++RRI++ + KKRK+Y+ F+ +P+L L+ E++ V D L S + GE ++ QG++ + FY++ G ++ K +DS E E+++ YFGE+AL+ N+PRAA+ A +KC+ +D + FER++G C +I+KRNI Y
Sbjct: 9 LTELLQSFTVEVLRNQPRDLLEFALQYFTQLK-----------ENESRGGAFGNEQNSAVRAGKAVNFIEEAMQ----IDSENEEDEDDDEEFVAPVINRFIRRASVCAEAFNPDEDDEDKEPRVTHPKTDEQRHRLQEACKDILLFKNLDQEQMSQVLDAMFDKAVTSGEHIIDQDDDGDNFYVIERGTFDILVKSDGTSRTVGSYDNRGSFGELALMYNTPRAATIVATSPGALWCLDRLTFRRIIVKNNAKKRKMYEAFIETLPLLTSLEVSERMKVVDVLSSKVYSKGEQIIAQGDLADSFYIVESGEVRITMKRNRLKTDSEEEEVDIATCTRGQYFGELALVTNKPRAASAYAVENVKCLVMDVQAFERLLGPCMDIMKRNIANY 384
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Sea Lamprey
Match: prkar2aa (protein kinase, cAMP-dependent, regulatory, type II, alpha A [Source:ZFIN;Acc:ZDB-GENE-030131-1007]) HSP 1 Score: 165.622 bits (418), Expect = 2.697e-48 Identity = 74/183 (40.44%), Postives = 121/183 (66.12%), Query Frame = 1
Query: 715 GSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVF-----QKPSDS--ENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKY 1242
GSFGELAL+Y TPRAAT+ A T+ LW +DR ++RRI++ + +KRK+Y+ F+ VP+L+ LD E++ V D + + +++DGE ++ QG + F+++ G ++ Q P+++ E E+E+ YFGE++L+ N+PRAA+ A G +KC + + FER++G C +I+KRNI Y
Sbjct: 24 GSFGELALMYNTPRAATIVATTEGSLWAMDRATFRRIILKNAAQKRKMYEAFIESVPLLKSLDASERMKVVDTITTKSYEDGEQIIAQGAKADCFFIVEAGEVRIMMKSKTQPPAETTKEGEVEIARCTRGQYFGELSLVTNKPRAASAYAVGNVKCAVMGVQPFERLLGPCMDIMKRNITHY 206 HSP 2 Score: 52.7582 bits (125), Expect = 3.937e-8 Identity = 36/119 (30.25%), Postives = 52/119 (43.70%), Query Frame = 1
Query: 517 IEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELN---------------CTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRIL 828
IE L LD ER + D + + E +I QG D F+I++ GEV I + + CT G FGEL+L+ PRAA+ A +VK + + R+L
Sbjct: 76 IESVPLLKSLDASERMKVVDTITTKSYEDGEQIIAQGAKADCFFIVEAGEVRIMMKSKTQPPAETTKEGEVEIARCT--RGQYFGELSLVTNKPRAASAYAVGNVKCAVMGVQPFERLL 192
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008271.1 (pep scaffold:Pmarinus_7.0:GL478901:32972:39586:1 gene:ENSPMAG00000007483.1 transcript:ENSPMAT00000008271.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 160.614 bits (405), Expect = 2.505e-47 Identity = 82/187 (43.85%), Postives = 111/187 (59.36%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQG 627
+ + E Y++ HNI LLKDC+V+LC+++P P+ F+RE+F+ LEK+ LK N + ND++ S + N + R RRGAVS EVYTE+D Y +KV+PKDYKTM+ALSKAI +NVLFSHLD+ ERSDIFDAMFP+ A +++IQQG
Sbjct: 8 VRDCERYVQKHNIQALLKDCIVQLCVARPERPMRFLREFFEKLEKEQLKTGWNNASGGNAANDVN---AASPTANPVI--------------------------------ATRNRRGAVSAEVYTEEDVKGYERKVIPKDYKTMAALSKAIARNVLFSHLDDSERSDIFDAMFPVTHIAGDVVIQQG 159
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Sea Lamprey
Match: si:ch211-272n13.7 (protein kinase cAMP-dependent type II regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9392]) HSP 1 Score: 154.451 bits (389), Expect = 4.306e-43 Identity = 103/322 (31.99%), Postives = 172/322 (53.42%), Query Frame = 1
Query: 103 IHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITN--NDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARL-----RRGAVSGEVYTEDDAASYVKKVV--PKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYV--NDELNC--TVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKV 1029
+ +LL+ V++ S+P + F YF + +Q ++ ++ + +D H + +N E+++AG D+ D +A + RR +V E Y D+ + V PK + + L +A + ++F +LD+++ S + DAMF + E +I QG DGDNFY+I++G +IYV ND C + GSFGELAL+Y T RAAT+ A ++ LWG+DR ++RRI++ + KKRK+Y+ F+ VP+L+ LD E+L V D + S +F D E ++ QGE + FY++ G ++
Sbjct: 9 LTELLQAFTVEVLRSRPADLLDFAAAYFAEM-RQRARERCGAPAQQLADGFDDAHGR---------GVNFSEENVAGHSSNSDNNGDDDRDDDDDDESDFEAPVISRFTRRASVCAEAYNPDEEEEDTETRVIHPKTDEQRNRLQEACKHILIFKNLDQEQMSQVLDAMFEKTVETGEHVIDQGADGDNFYVIERGMYDIYVTTNDVSRCVGAYNNRGSFGELALMYNTSRAATIIATSEGALWGLDRLTFRRIIVKNAAKKRKMYECFIETVPLLKSLDFSERLKVVDVIASKSFQDSERIIAQGEKADCFYLVESGEVRI 320 HSP 2 Score: 63.5438 bits (153), Expect = 2.861e-11 Identity = 45/144 (31.25%), Postives = 69/144 (47.92%), Query Frame = 1
Query: 820 RILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSY 1251
R++ T ++R QE + I + LD+ + V DA+ + GE+V+ QG G++FY+I G+ ++ +D VG FGE+AL+ N RAAT+ A LDR F R+ I+K KK Y
Sbjct: 129 RVIHPKTDEQRNRLQEACKHILIFKNLDQEQMSQVLDAMFEKTVETGEHVIDQGADGDNFYVIERGMYDIYVTTNDVSR--CVGAYNNRGSFGELALMYNTSRAATIIATSEGALWGLDRLTFRRI------IVKNAAKKRKMY 264
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005026.1 (pep scaffold:Pmarinus_7.0:GL484567:1893:8879:-1 gene:ENSPMAG00000004571.1 transcript:ENSPMAT00000005026.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 134.806 bits (338), Expect = 1.400e-38 Identity = 65/95 (68.42%), Postives = 77/95 (81.05%), Query Frame = 1
Query: 607 EILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPIL 891
EI+ Q D I+ EVE+YVN EL ++ EGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V IL
Sbjct: 1 EIVETQNKDCLRLNIVCDSEVEVYVNVELVTSIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSIL 95 HSP 2 Score: 43.8986 bits (102), Expect = 5.215e-6 Identity = 33/77 (42.86%), Postives = 43/77 (55.84%), Query Frame = 1
Query: 1045 DSENEIEVG-ELLTS----DYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERV-MGSCAEILKRNIKKYNSYIS 1257
DSE E+ V EL+TS FGE+AL+ PRAATV+A LK +DR + R+ MGS R K Y ++S
Sbjct: 18 DSEVEVYVNVELVTSIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTL----RKRKMYEEFLS 90
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006754.1 (pep scaffold:Pmarinus_7.0:GL480706:4401:8544:-1 gene:ENSPMAG00000006099.1 transcript:ENSPMAT00000006754.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 130.183 bits (326), Expect = 3.226e-36 Identity = 76/165 (46.06%), Postives = 99/165 (60.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKER 561
L E EEY++ H I +LK C+V+LC+++P P+ F+RE+F+ LEK+ K L+ + S S +DS E EI N VV K R RR A S EVYTE+DAASYV+KV+PKDYKTM+ALSKAI++NVLFSHLD+ ER
Sbjct: 14 LRECEEYVQRHGIQAVLKQCIVQLCIARPERPMQFLREHFERLEKEEAKQFLS--------------RRMSNSLSDSWEE--------EISPPPPN-----PVV------KGRSRRMAFSAEVYTEEDAASYVRKVIPKDYKTMAALSKAIQRNVLFSHLDDNER 145
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Yeast
Match: BCY1 (Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA); PKA is a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation [Source:SGD;Acc:S000001295]) HSP 1 Score: 194.126 bits (492), Expect = 4.032e-57 Identity = 103/279 (36.92%), Postives = 162/279 (58.06%), Query Frame = 1
Query: 409 RRGAVSGEVYTEDDAASYVKKVVPKDYK-----TMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRN 1230
RR +VSGE ++ + P YK + L K+I N LF+ LD + + + + +I+QGD GD FY++++G V+ YVND + G SFGELAL+Y +PRAATV A +D LW +DR ++R+IL+GS+ KKR +Y + L +P+L+ L +++ +ADAL++ + GE ++++G+ GE+FY+I G V +K + + +L DYFGE+ALL + PR ATV A K L + F+R++G ++LK N
Sbjct: 142 RRTSVSGETLQPNNFDDWT----PDHYKEKSEQQLQRLEKSIRNNFLFNKLDSDSKRLVINCLEEKSVPKGATIIKQGDQGDYFYVVEKGTVDFYVNDNKVNSSGPGSSFGELALMYNSPRAATVVATSDCLLWALDRLTFRKILLGSSFKKRLMYDDLLKSMPVLKSLTTYDRAKLADALDTKIYQPGETIIREGDQGENFYLIEYGAVDVSKK-----GQGVINKLKDHDYFGEVALLNDLPRQATVTATKRTKVATLGKSGFQRLLGPAVDVLKLN 411
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Nematostella
Match: EDO48439 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJW7]) HSP 1 Score: 450.669 bits (1158), Expect = 1.055e-156 Identity = 232/405 (57.28%), Postives = 288/405 (71.11%), Query Frame = 1
Query: 55 NASYLEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVND-ELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
+A L + E Y++ HNI +LKDC+V+LC+SKP +P F REYF+ LEK+ L E+E E E+E+H + R RRGAVS TED+A SYVKKVVPKDYKTM+ALSKAI KN+LFSHLDE ERSDIFDAM + A EI+I+QGD+GDNFYI+D GEV+++VN+ L T+ EGGSFGELALIYGTPRAAT++A TDVKLW IDR +YRRILMGS I+KR++Y++FL +V ILE LDKWE+LTVADALE F DG+ VV QGE G++F++I+EG A V Q+ S +E+ IEV L SDYFGEIAL+LNRPRAATVQA G LKCVKLDR+RFERV+G C +ILKRNI++YNS++S+ V
Sbjct: 10 DAEALRQCEIYVEKHNIQGVLKDCIVQLCISKPENPYKFFREYFEKLEKKEETARL-EAEPE------------------QRAEVEEHPPPSKPF--------------------QRQRRGAVSAAPITEDEATSYVKKVVPKDYKTMAALSKAITKNILFSHLDENERSDIFDAMSLVKHGAGEIIIKQGDEGDNFYIVDSGEVDVFVNNVGLVSTIGEGGSFGELALIYGTPRAATIKAKTDVKLWAIDRVTYRRILMGSQIRKRRMYEQFLEKVSILESLDKWERLTVADALEPTQFQDGDDVVVQGEHGDEFFIIVEGTAVVLQRRSANEDFIEVSRLGPSDYFGEIALVLNRPRAATVQARGTLKCVKLDRQRFERVLGPCIDILKRNIQQYNSFVSLVV 375
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Nematostella
Match: EDO38262 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDH8]) HSP 1 Score: 221.476 bits (563), Expect = 2.154e-67 Identity = 134/387 (34.63%), Postives = 211/387 (54.52%), Query Frame = 1
Query: 103 IHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTED--DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYV----NDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKV-FQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKY 1242
+ LL+D V + KP V F YF L+ LK+ ++ + + +D+ NE ED DE K++ AR R +V E + D D V PK + L+ AI+ +LF +L +++ +++ DAMF +A + +I QGDDGDNFY+ID+G+ +IYV +++ + GSFGELAL+Y TPRAAT+ + ++ +WG+DR ++RRIL+ + KKRK+++ L VP+L+E+ ++E++ +ADAL S F DGE ++KQG+ + Y + G + SD E+E+ + YFGE+AL+ + RAA+V + G C LD FER++G C +I+KRNI Y
Sbjct: 9 LSDLLQDFTVHVLREKPEDIVDFAANYFMKLK---LKEKRSQKGKKKNKEKGVSFGPPGNDEDDTYNEDED--------------DEMPE---PPKNRYAR--RQSVCAEPFHPDSEDEGDEQPIVYPKTDEQRQRLNDAIKNILLFKNLAKEQLNEVLDAMFERKTQAGDHIIDQGDDGDNFYVIDRGQYDIYVRIDGQEKMVGSYDNKGSFGELALMYNTPRAATIVSTSEGVIWGLDRMTFRRILLKAAAKKRKVHEALLETVPLLQEITEYERMNLADALVSRQFKDGECIIKQGDEADFMYFVESGTVSIRMHNKSDPTTEVEIAQCTKGGYFGELALITHNTRAASVYSVGDCVCASLDVHAFERLLGPCMDIMKRNIDGY 373
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Nematostella
Match: EDO49534 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGJ3]) HSP 1 Score: 183.726 bits (465), Expect = 4.809e-53 Identity = 121/389 (31.11%), Postives = 198/389 (50.90%), Query Frame = 1
Query: 97 HNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDA-ASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVN----DELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEV-GELLTSDYFGEIALLLNRPRAATVQA-CGPLKCVKLDRKRFERVMGSCAEILKRNIKKY 1242
+H+LL+ ++ + +P+ V F YF L + IH+ S S E ED E + L + + S ++ + LRR +V+GEVY ++ ++ PK L I +F + + + + DAM+ E +I+QGD GDNFYIID+GE E+ E + GSFGELAL+Y PR+AT+RA T LW +DR S+RRIL+ +T +KR+ Y+ L R+P+L +L +E+ ++ADAL + + D E +++Q + + Y I G+ ++ + S ++++V +YFGE+AL+ R A+V A G + C L+ FER++G C +++RN+K Y
Sbjct: 8 QELHKLLQSFILDVFTEQPDDLVDFAASYFSKLN--------------TSRKPIHS------SSTPSTQE-EDDFYCSESLSLPSDRFKRPSY---QQNHRLYLRRDSVAGEVYEPVNSNCVSAQRFYPKSEDARKRLENVIGNIFIFKSCGKDQINMMLDAMYERVVYQEETIIRQGDAGDNFYIIDEGEFEVLFETNGAQEKLGRLKGPGSFGELALMYNCPRSATIRACTPGVLWVLDRKSFRRILVDTTERKRRHYETLLERIPVLSQLTAYERTSLADALTTSVYRDEECIIRQDDPADCLYFIESGIVEISIRDSKDRSKVKVISTAGPGEYFGELALVNKTKRGASVHAKGGQVTCAVLEVNAFERLLGPCKGLMQRNMKTY 372
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Nematostella
Match: EDO41163 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S513]) HSP 1 Score: 176.792 bits (447), Expect = 1.523e-50 Identity = 108/289 (37.37%), Postives = 162/289 (56.06%), Query Frame = 1
Query: 397 KARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNC------TVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQG-EVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKY 1242
K R RR AVS E Y ++ A + K PK + + L K + + LF ++ I D+MF EI+I+ GD+GDNFY+I+ GE +++ D T + G FGELAL++ + R AT+ A T+ LW +DR ++ ++++G ++R+ E L V IL+EL E V+DAL F DGE V+++G E Y I +G +V K + E +E +YFGE+AL++N+PR+A+V A G K L + FER+MG C EI+KRN K+Y
Sbjct: 78 KGRSRRAAVSAEPYNPNENADFKAKFHPKSEEQRNHLKKKLLELWLFEKFHREDLDVILDSMFEKKVSPEEIIIKVGDEGDNFYVINTGEYDVFALDTNTGASIKVHTFNGTGMFGELALMHNSLRNATIVAKTEGTLWALDRSTFVQVVVGGAQRRRERNIELLKSVSILKELKPDELDKVSDALYPKEFKDGEAVIREGNESAYCMYFIEKGKVRVTVKDGEVEKTVE----FDKNYFGELALVMNQPRSASVYAVGECKFASLKKDDFERLMGPCKEIMKRNAKEY 362
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Nematostella
Match: EDO38399 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCY8]) HSP 1 Score: 151.369 bits (381), Expect = 2.203e-39 Identity = 96/292 (32.88%), Postives = 160/292 (54.79%), Query Frame = 1
Query: 385 AKDKKARLR------RGAVSGEVYTEDDAASYVKKVV---PKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQA-CGPLKCVKLDRKRFERVMGSCAEILKRN 1230
A ++K +LR R AVSGE T+ S K + PKD+++ + AI +N +L+ + +I D M+ + N+++IQ+GD G+ Y I G +++ +++ + G FGELA++Y R ATV A KLW IDR ++ I+M + + ++ + FL VP+L+EL E +AD LE + G+Y++++ E G+ FY+I +G A+V Q+ E+ +L DYFGE ALL R A V A ++C+ +DR F V+G+ E+ +++
Sbjct: 7 APERKKKLRPSKKEKRQAVSGESSTKAQEESRTGKELERFPKDFRSKQLIKDAIFENDFLKNLEAAQVREIVDCMYSNTFQRNDVIIQEGDAGNALYAIADGRLQVTRENKVLGEMVAGMVFGELAILYNCRRTATVTAMEPTKLWKIDRRVFQIIMMRTGMIRQAEHMAFLKSVPLLKELPNAELSKLADVLEVDFYHAGDYIIRENERGDTFYIITKGSARVTQRIEGQTGPKEIRKLQKGDYFGEKALLSEDRRTANVIAEENGVECLVVDRTVFMTVIGNMDELREKD 298
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Medaka
Match: prkar1b (protein kinase cAMP-dependent type I regulatory subunit beta [Source:NCBI gene;Acc:101155602]) HSP 1 Score: 497.664 bits (1280), Expect = 8.714e-175 Identity = 243/400 (60.75%), Postives = 300/400 (75.00%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L+ E +++ HNI Q+LK+C+V LC++KP P+ F+RE+F+ LEK+ K + +S + +D H D+ S KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A E +IQQGD+GDNFY+IDQGEV++YVN EL + EGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DGE +V QGE G+DF++I EG+A V Q+ SD+E +EVG L SDYFGEIALLLNRPRAATV A GPLKCVKLDR RFERV+G C+EILKRNI++YNS+IS+TV
Sbjct: 14 LKSCEIFVQKHNIQQILKECIVNLCIAKPERPMKFLREHFEKLEKEECKHIMARQKSN-SQSDSH--------------------------------DDEVSPPPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGDEGDNFYVIDQGEVDVYVNGELVTNIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGIASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 380
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Medaka
Match: prkar1ab (protein kinase cAMP-dependent type I regulatory subunit alpha [Source:NCBI gene;Acc:101156203]) HSP 1 Score: 496.123 bits (1276), Expect = 3.300e-174 Identity = 241/400 (60.25%), Postives = 305/400 (76.25%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
L E E+Y++ HNI QLLKDC+V+LC S+P+ P++F+REYF+ LEK+ K I N++ S +DS +E V + V K R RRGA S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLF+HLD+ ERSDIFDAMFP+ A E +I QGD+GDNFY+IDQGE+++YVN+E ++ EGGSFGELALIYGTPRAATV+A T+VKLWGIDRDSYRRILMGST++KRK+Y+EFL +V ILE LDKWE+LTVADALE + F+DG+ +V QGE G++F++I+EG A V Q+ S+ E +EVG L SDYFGEIALL+NRPRAATV A GPLKCVKLDR RFERV+G C++ILKRNI++YNS++S++V
Sbjct: 14 LRECEQYVQKHNIQQLLKDCIVQLCTSRPDRPMAFLREYFERLEKEEAKQ-------------IQNQQKAGSSRSDSRDE---------------EVSPPMNPVV-----KGRRRRGAFSAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFAHLDDNERSDIFDAMFPVTYIAGETVILQGDEGDNFYVIDQGEMDVYVNNEWVTSIGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLRKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSEHEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 380
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Medaka
Match: prkar1b (protein kinase cAMP-dependent type I regulatory subunit beta [Source:NCBI gene;Acc:101155602]) HSP 1 Score: 401.364 bits (1030), Expect = 1.554e-137 Identity = 198/348 (56.90%), Postives = 250/348 (71.84%), Query Frame = 1
Query: 67 LEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIAL 1110
L+ E +++ HNI Q+LK+C+V LC++KP P+ F+RE+F+ LEK+ K + +S + +D H D+ S KAR RRG VS EVYTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A E +IQQGD+GDNFY+IDQGEV++YVN EL + EGGSFGELALIYGTPRAATV+A TD+KLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADALE + F+DGE +V QGE G+DF++I EG+A V Q+ SD+E +EVG L SDYFG+ L
Sbjct: 14 LKSCEIFVQKHNIQQILKECIVNLCIAKPERPMKFLREHFEKLEKEECKHIMARQKSN-SQSDSH--------------------------------DDEVSPPPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGDEGDNFYVIDQGEVDVYVNGELVTNIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGIASVLQRRSDNEEYVEVGRLGPSDYFGQCHL 328 HSP 2 Score: 65.0846 bits (157), Expect = 4.841e-11 Identity = 50/157 (31.85%), Postives = 78/157 (49.68%), Query Frame = 1
Query: 802 DRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTS----DYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERV-MGSCAEILKRNIKKYNSYIS 1257
D SY R ++ K + +S+ + LD E+ + DA+ + GE V++QG+ G++FY+I +G V+ GEL+T+ FGE+AL+ PRAATV+A LK +DR + R+ MGS R K Y ++S
Sbjct: 108 DAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGDEGDNFYVIDQGEVDVYVN----------GELVTNIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTL----RKRKMYEEFLS 250
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Medaka
Match: prkar2aa (cAMP-dependent protein kinase type II-alpha regulatory subunit [Source:NCBI gene;Acc:101159349]) HSP 1 Score: 214.927 bits (546), Expect = 2.713e-64 Identity = 114/285 (40.00%), Postives = 172/285 (60.35%), Query Frame = 1
Query: 409 RRGAVSGEVYTEDDAASYVKKVV--PKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSEN-----EIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKY 1242
RR +V E + DD + V PK + L +A +LF LD+++ S + DAMF L + E +I QG DGDNFY+I++G +I V+ + + GSFGELAL+Y TPRAAT+ A + LWG+DR ++RR+++ + KKR++Y+ F+ VP+L+ L+ E++ + D L F DGE ++ QGE E FY++ G K+ K + E+E+ YFGE+AL+ N+PRAA+ A G +KC+ +D + FER++GSC EI+KRNI Y
Sbjct: 91 RRVSVCAEAFNPDDDDEDTEPRVVHPKTDEQRCRLQEACRDILLFKTLDQEQFSQVLDAMFELKVQPQEHVIDQGHDGDNFYVIERGIYDIVVSGKCVGQYNNKGSFGELALMYNTPRAATIIATQEGALWGLDRATFRRLIVKNNAKKRRMYETFIESVPLLKTLEPNERMKIVDVLGMKQFLDGERIIAQGEKAECFYIVESGEVKIMMKSKTKADHADNAEVEITRCSRGQYFGELALVTNKPRAASAYAVGDVKCLVIDVQAFERLLGSCKEIMKRNISHY 375
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Medaka
Match: si:ch211-272n13.7 (protein kinase cAMP-dependent type II regulatory subunit beta [Source:NCBI gene;Acc:101166375]) HSP 1 Score: 207.994 bits (528), Expect = 1.775e-61 Identity = 109/291 (37.46%), Postives = 170/291 (58.42%), Query Frame = 1
Query: 406 LRRGAVSGEVYT--EDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVN----DELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPS------DSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKY 1242
+RR +V E + ED+ + PK + L +A +LF +LD +E S + DAMF E +I Q DDGDNFY+I+ G I+V ++L GSFGELAL+Y TPRAAT+ A + LW +DR ++RRI++ + KKR+LY+ F+ +P+L L+ E++ V D L + ++D + ++ QG++ + FY++ G ++ K S E E+E+ YFGE+AL+ N+PRAA+ A G +KC+ +D + FER++G C +I+KRNI Y
Sbjct: 100 IRRASVCAEAFNPDEDEEDKEPRVTYPKTDEQRQRLQEACRDILLFKNLDPEEISQVLDAMFEKFCTEGEHIIDQDDDGDNFYVIESGTFNIFVKVDGIEKLVGCYDNRGSFGELALMYNTPRAATIIATSPGALWCLDRLTFRRIIVKNNAKKRRLYEAFIETLPLLTSLETSERMKVVDVLSTRVYNDSQQIIAQGDLADCFYIVESGQVRITMKRSRMTKKDQEEEEVEIATCTRGQYFGELALVTNKPRAASAYAVGSVKCLVMDVQAFERLLGPCMDIMKRNIANY 390
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Planmine SMEST
Match: SMESG000074764.1 (SMESG000074764.1) HSP 1 Score: 830.091 bits (2143), Expect = 0.000e+0 Identity = 403/405 (99.51%), Postives = 404/405 (99.75%), Query Frame = 1
Query: 52 MNASYLEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
MNASYLE+LEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNL DNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV
Sbjct: 1 MNASYLEDLEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLNDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 405
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Planmine SMEST
Match: SMESG000006310.1 (SMESG000006310.1) HSP 1 Score: 354.369 bits (908), Expect = 7.168e-121 Identity = 165/229 (72.05%), Postives = 200/229 (87.34%), Query Frame = 1
Query: 580 MFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYISITV 1266
MFP+H+ EI+IQQGD+GDNFYIIDQG+V+I +N E +V EGGSFGELALIYGTPRAATVRA T+VKLWGIDRDSYRRILMGSTI+KR++Y+EFLS+VPILE LDKWE+LTVADALE++ F++ + VVKQG+ G+DF++I +G A V Q+P D+E EVG+L SDYFGEI+LLL+RPRAATV A GPLKCVKLDRKRFERV+G C++ILKRNI KYNS+IS+TV
Sbjct: 1 MFPVHRNPAEIIIQQGDEGDNFYIIDQGQVDIIMNGEYVNSVVEGGSFGELALIYGTPRAATVRARTEVKLWGIDRDSYRRILMGSTIRKRRMYEEFLSKVPILENLDKWERLTVADALETVCFENNQIVVKQGDPGDDFFIITDGTAAVLQQPMDTEESFEVGKLGPSDYFGEISLLLDRPRAATVIAKGPLKCVKLDRKRFERVLGPCSDILKRNISKYNSFISLTV 229 HSP 2 Score: 63.1586 bits (152), Expect = 4.864e-11 Identity = 47/152 (30.92%), Postives = 80/152 (52.63%), Query Frame = 1
Query: 448 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIY---VNDELNCTVSEGGS---FGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMG-STIKKRKL--YQEFLS 876
D SY + ++ + + + K + +LD+ ER + DA+ + + N+I+++QGD GD+F+II G + ++ E + V + G FGE++L+ PRAATV A +K +DR + R+L S I KR + Y F+S
Sbjct: 75 DRDSYRRILMGSTIRKRRMYEEFLSKVPILENLDKWERLTVADALETVCFENNQIVVKQGDPGDDFFIITDGTAAVLQQPMDTEESFEVGKLGPSDYFGEISLLLDRPRAATVIAKGPLKCVKLDRKRFERVLGPCSDILKRNISKYNSFIS 226
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Planmine SMEST
Match: SMESG000017499.1 (SMESG000017499.1) HSP 1 Score: 210.305 bits (534), Expect = 6.171e-63 Identity = 126/389 (32.39%), Postives = 210/389 (53.98%), Query Frame = 1
Query: 103 IHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQN--LKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVY---TEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVNDELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNSYI 1254
+ +LL++ + + KP++ V + EYF++L ++ + ++ N + SE ++ND + KK R RR +V+ E + EDD V + K S L +AI+ LF LD+++R + D+M + ++++ +I QGD GD+FY+I++G +I+VN S+ GSFGELAL+Y TPRAAT+ + T+ LW +DR ++R I++ + KKR++Y+ L V +L+EL +++ VADAL S ++D E +++QG+ G + + I G +V + +D EV L DYFGE+ALL+ PR A+V A G LD K FER++G C ++K+N+ KY + +
Sbjct: 12 LTELLQNFAISVLRHKPHNLVHYAFEYFKDLSSKHEEINNSGNHTHSEDSDNDDNIKKQVQ-----------------------------------------RGRRQSVAAESFDPEKEDDEDLPV--IYSKTDAQRSRLVEAIKPIFLFRSLDDEQRGKVIDSMREVVVESDQKVIVQGDGGDDFYVIEKGMFDIFVNGSKIGNYSDTGSFGELALMYNTPRAATIISVTNGILWAMDRKTFRHIVLKNAFKKRQMYEGLLQSVDLLDELSSYDRTNVADALVSRTYEDSEMILEQGKPGMEMFFIENGEVRVIRDTNDGSPPKEVNRLHKGDYFGEVALLIKEPRLASVYAVGKTTVAVLDIKSFERLLGPCINLMKKNLPKYRNQL 357
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Planmine SMEST
Match: SMESG000023850.1 (SMESG000023850.1) HSP 1 Score: 204.527 bits (519), Expect = 1.199e-60 Identity = 132/389 (33.93%), Postives = 200/389 (51.41%), Query Frame = 1
Query: 109 QLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGE--VYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVND----ELNCTVSEGGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEG---VAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKYNS 1248
++L D ++ +P+ V ++ YF +I + HNK S HND + + L ++D S K KA RR +V+ E + D + V+PK + L + ++ +LF LD+ + + + +AMF + K E +I QGDDGDNFY+ID G Y+ D +L G FGELAL+Y R+ATV A T LW +DR ++R +++ T ++++Y FL + PI +E+ E++ +ADAL +DD E ++KQG G++ + I G + KV Q EIE+ L YFGE+ALL N+ R A+ QA G +C LD K FER+MG C EI+KRNI+ YN+
Sbjct: 14 EMLVDLTFEVLKDQPDDFVEYVSNYF----------------LKIYDEQGHNKVYKS-PHNDQSDSF--------VNSLLDSLDSIDSEDIEVK-PKANYRRKSVAAERIDMDDIDDDDDIYAVIPKTDEQRQRLKEVCKQILLFQALDDDQLNHVINAMFLVEPKPGENIIVQGDDGDNFYVIDSGIFNCYIKDGDKDKLIHVYENEGFFGELALMYNAVRSATVTAETAGTLWAMDRKTFRSLVVVQTHNRKQIYDTFLKQFPIFQEMTASERMNIADALVPKKYDDKEVIIKQGRPGQEMFFIENGEVLITKVHQG-----KEIEITRLHVGQYFGELALLSNQARQASAQAVGETRCAMLDVKTFERLMGPCLEIMKRNIEDYNT 371
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Planmine SMEST
Match: SMESG000019065.1 (SMESG000019065.1) HSP 1 Score: 194.897 bits (494), Expect = 5.006e-57 Identity = 123/393 (31.30%), Postives = 201/393 (51.15%), Query Frame = 1
Query: 82 EYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKQNLKDNLNESESEITNNDIHNKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEVY--TEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKANEILIQQGDDGDNFYIIDQGEVEIYVN-DELNCTVSE---GGSFGELALIYGTPRAATVRAATDVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEELDKWEQLTVADALESINFDDGEYVVKQGEVGEDFYMIIEGVAKVFQKPSDSENEIEVGELLTSDYFGEIALLLNRPRAATVQACGPLKCVKLDRKRFERVMGSCAEILKRNIKKY 1242
E + +LL+D V + P + F +YF+ + + L+ +SESE ++D + EL + + RR V+ E + ++D + + V PK + + L+ A++ +LF LDE++ D+ DAMF E +I QG+DGDNFY+I+ G +I V + ++ V + GSFGELAL+Y TPRAAT++ D +W + R+++R I++ +KR Y+ L VP+L+EL +E++ +ADAL + ++ ++KQGE G + Y + EG +V + + S+ E EV + YFGE+ALL PRAA+V K LD FER++G C +I++R+I Y
Sbjct: 5 EVVIPPGFKELLQDFTVCVLRDNPEDIIQFGIDYFKTKKSEQLQSAHLDSESE---------------NDDQMEELPPM-------------------------PRPQGRRRGVAAESFDPEKEDDPNQERIVYPKTPEQRARLNMAVQNILLFRCLDEEQMVDVIDAMFERRVVQGEKVIIQGEDGDNFYVIESGTYDIIVKINGVDTKVGKYDGSGSFGELALMYNTPRAATIQTVNDGVVWAMTRETFRSIVLKKAFQKRLKYEALLENVPLLKELSPYERMNIADALLTRIYEPNTTIIKQGEPGLEMYFLEEGCVRVTVREAGSDTEAEVTRIGPGGYFGELALLTKHPRAASVYCVEKTKLAILDVGSFERLLGPCLDIMQRSISNY 357 The following BLAST results are available for this feature:
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type I-alpha regulatory subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30007839 ID=SMED30007839|Name=cAMP-dependent protein kinase type I-alpha regulatory subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1541bpback to top protein sequence of SMED30007839-orf-1 >SMED30007839-orf-1 ID=SMED30007839-orf-1|Name=SMED30007839-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=406bp MNASYLEELEEYIKVHNIHQLLKDCVVKLCLSKPNSPVSFIREYFQNLEKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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