Essential myosin light chain

Overview


Name	Essential myosin light chain
Smed ID	SMED30007795
Length (bp)	864

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Essential myosin light chain (SMED30007795) t-SNE clustered cells

Violin plots show distribution of expression levels for Essential myosin light chain (SMED30007795) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Essential myosin light chain (SMED30007795) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Essential myosin light chain (SMED30007795) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30007795

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
gut	SMED30007795	h1SMcG0015803	Contig1602	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30007795	h1SMcG0015803	Contig1602	GPL15192	PMID:23079596 Forsthoefel et al., 2012
protonephridia	SMED30007795	h1SMcG0015803	dd_Smed_v4_559_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30007795	h1SMcG0015803	dd_Smed_v4_559_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30007795	h1SMcG0015803	dd_Smed_v4_559_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30007795	h1SMcG0015803	dd_Smed_v4_559_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30007795	h1SMcG0015803	dd_Smed_v4_559_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Essential myosin light chain vs. Ensembl Human
Match: MYL1 (myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:7582])

HSP 1 Score: 141.739 bits (356), Expect = 1.518e-41
Identity = 69/137 (50.36%), Postives = 96/137 (70.07%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            E F LFD  GDSKI   Q+G+V+RALG NPT AE++K   N  +E     +I FE F+P+ Q++   K  +  ++FVEG +VFDK+GNG +  AELRH+L  +GE+++E EV+AL+AG E+S G I+YE FV HIM+
Sbjct:   13 EAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMS 149

[Close]

BLAST of Essential myosin light chain vs. Ensembl Human
Match: MYL1 (myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:7582])

HSP 1 Score: 141.739 bits (356), Expect = 6.572e-41
Identity = 69/137 (50.36%), Postives = 96/137 (70.07%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            E F LFD  GDSKI   Q+G+V+RALG NPT AE++K   N  +E     +I FE F+P+ Q++   K  +  ++FVEG +VFDK+GNG +  AELRH+L  +GE+++E EV+AL+AG E+S G I+YE FV HIM+
Sbjct:   57 EAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMS 193

[Close]

BLAST of Essential myosin light chain vs. Ensembl Human
Match: MYL6B (myosin light chain 6B [Source:HGNC Symbol;Acc:HGNC:29823])

HSP 1 Score: 131.339 bits (329), Expect = 1.090e-36
Identity = 67/143 (46.85%), Postives = 96/143 (67.13%), Query Frame = 2

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKC-GYNNQDE----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            +L +  E F LFD  GD KI   Q G+V+RALG NPT AE+ K  G    DE    R+ FE F+P+ Q++ K +     ++++EGF+VFDK+GNG +  AELRH+LT +GE++ E EV+ +LAG E+S G I+YE F+ HI++
Sbjct:   65 QLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGHEDSNGCINYEAFLKHILS 207

[Close]

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKC-GYNNQDE----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            +L +  E F LFD  GD KI   Q G+V+RALG NPT AE+ K  G    DE    R+ FE F+P+ Q++ K +     ++++EGF+VFDK+GNG +  AELRH+LT +GE++ E EV+ +LAG E+S G I+YE F+ HI++
Sbjct:   65 QLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGHEDSNGCINYEAFLKHILS 207

[Close]

BLAST of Essential myosin light chain vs. Ensembl Human
Match: MYL6 (myosin light chain 6 [Source:HGNC Symbol;Acc:HGNC:7587])

HSP 1 Score: 128.257 bits (321), Expect = 3.152e-36
Identity = 68/150 (45.33%), Postives = 95/150 (63.33%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKC-GYNNQDER----ISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            M   TE +  +  E F LFD  GD KI   Q G+V+RALG NPT AE+ K  G    DE     + FE F+P+ Q++ K K     +++VEG +VFDK+GNG +  AE+RH+L  +GE++ E EV+ L+AG E+S G I+YE FV HI++
Sbjct:    1 MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILS 150

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BLAST of Essential myosin light chain vs. Ensembl Celegans
Match: mlc-5 (Myosin-2 essential light chain [Source:UniProtKB/Swiss-Prot;Acc:Q9XVI9])

HSP 1 Score: 156.377 bits (394), Expect = 9.360e-48
Identity = 75/139 (53.96%), Postives = 101/139 (72.66%), Query Frame = 2

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKC-GYNNQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            +L D  E FA FD+KGD +I  +Q+G+V+RALG NPTEAEI KC G  +++ R+SFE F+PI+QS+ K +     +EFVEG   FDK+GNGMI+ AELRHLLT +GERL + +VD LL+G  +S G ++  DFV  +MN
Sbjct:    3 DLADCREVFAYFDSKGDERISVQQVGDVLRALGQNPTEAEIHKCVGSFDREARLSFEDFVPIFQSVSKNREKHTVEEFVEGLSHFDKEGNGMINVAELRHLLTTLGERLSDEDVDQLLSGHNDSHGNVNISDFVRAVMN 141

[Close]

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKC-GYNNQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            +L D  E FA FD+KGD +I  +Q+G+V+RALG NPTEAEI KC G  +++ R+SFE F+PI+QS+ K +     +EFVEG   FDK+GNGMI+ AELRHLLT +GERL + +VD LL+G  +S G ++  DFV  +MN
Sbjct:    3 DLADCREVFAYFDSKGDERISVQQVGDVLRALGQNPTEAEIHKCVGSFDREARLSFEDFVPIFQSVSKNREKHTVEEFVEGLSHFDKEGNGMINVAELRHLLTTLGERLSDEDVDQLLSGHNDSHGNVNISDFVRAVMN 141

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BLAST of Essential myosin light chain vs. Ensembl Celegans
Match: mlc-3 (Myosin, essential light chain [Source:UniProtKB/Swiss-Prot;Acc:P53014])

HSP 1 Score: 120.168 bits (300), Expect = 1.722e-33
Identity = 59/135 (43.70%), Postives = 86/135 (63.70%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCG----YNNQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIM 526
            E F L+D + D KI+  Q+G+V RA GL PT+A + K          ++R++FE ++P+Y+ L K+K      +F EG KVFDK+  G I AAELRH+L A+GERL   E D LL G+E+ +G + YEDF+  ++
Sbjct:   11 EIFNLYDEELDGKIDGTQVGDVARAAGLKPTQAMVTKAAGQEFKRKGEKRLTFEEWLPMYEQLAKEKEQGTYADFYEGLKVFDKEETGKILAAELRHILLALGERLSADEADELLKGVEDGEGMVKYEDFIKKVL 145

[Close]

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCG----YNNQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIM 526
            E F L+D + D KI+  Q+G+V RA GL PT+A + K          ++R++FE ++P+Y+ L K+K      +F EG KVFDK+  G I AAELRH+L A+GERL   E D LL G+E+ +G + YEDF+  ++
Sbjct:   11 EIFNLYDEELDGKIDGTQVGDVARAAGLKPTQAMVTKAAGQEFKRKGEKRLTFEEWLPMYEQLAKEKEQGTYADFYEGLKVFDKEETGKILAAELRHILLALGERLSADEADELLKGVEDGEGMVKYEDFIKKVL 145

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BLAST of Essential myosin light chain vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 110.923 bits (276), Expect = 4.669e-30
Identity = 61/141 (43.26%), Postives = 92/141 (65.25%), Query Frame = 2

Query:  101 RLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKV--VSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGME-NSQGQISYEDFV 514
            +LTE ++ +  E F+LFD  GD  I  K++G V+R+LG NPTEAE++    N  D   +  I  P + ++M +K+      +E  E F+VFDKDGNG ISAAELRH++T +GE+L + EVD ++   + +  GQ++YE+FV
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM-INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

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BLAST of Essential myosin light chain vs. Ensembl Fly
Match: Mlc-c (gene:FBgn0004687 transcript:FBtr0070783)

HSP 1 Score: 162.155 bits (409), Expect = 8.416e-50
Identity = 77/146 (52.74%), Postives = 106/146 (72.60%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYN-NQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            MA  TE +L +  E F LFD +GD KI+  Q+GE +RALG NPTE+++KKC +    DERISFE+F+PIYQ++ K +      +F+EG + FDKD +G IS+AELRHLLT +GE+L + EV+ LLA ME+ QG I+YE+FV  +M+
Sbjct:    1 MAAYTEDQLAEFQEAFNLFDNRGDGKIQLSQVGECLRALGQNPTESDVKKCTHQLKPDERISFEVFLPIYQAISKARSGDTADDFIEGLRHFDKDASGYISSAELRHLLTTLGEKLTDEEVEQLLANMEDQQGNINYEEFVRMVMS 146

[Close]

BLAST of Essential myosin light chain vs. Ensembl Fly
Match: Mlc-c (gene:FBgn0004687 transcript:FBtr0308579)

HSP 1 Score: 159.458 bits (402), Expect = 1.073e-48
Identity = 75/152 (49.34%), Postives = 106/152 (69.74%), Query Frame = 2

Query:   77 IYFLLKMARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYN-NQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            +Y+     + T   L +  E F LFD +GD KI+  Q+GE +RALG NPTE+++KKC +    DERISFE+F+PIYQ++ K +      +F+EG + FDKD +G IS+AELRHLLT +GE+L + EV+ LLA ME+ QG I+YE+FV  +M+
Sbjct:    1 MYYYTAHVKQTFTTLEEFQEAFNLFDNRGDGKIQLSQVGECLRALGQNPTESDVKKCTHQLKPDERISFEVFLPIYQAISKARSGDTADDFIEGLRHFDKDASGYISSAELRHLLTTLGEKLTDEEVEQLLANMEDQQGNINYEEFVRMVMS 152

[Close]

BLAST of Essential myosin light chain vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304964)

HSP 1 Score: 110.923 bits (276), Expect = 6.383e-30
Identity = 61/141 (43.26%), Postives = 92/141 (65.25%), Query Frame = 2

Query:  101 RLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKV--VSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGME-NSQGQISYEDFV 514
            +LTE ++ +  E F+LFD  GD  I  K++G V+R+LG NPTEAE++    N  D   +  I  P + ++M +K+      +E  E F+VFDKDGNG ISAAELRH++T +GE+L + EVD ++   + +  GQ++YE+FV
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM-INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of Essential myosin light chain vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0088001)

HSP 1 Score: 110.923 bits (276), Expect = 6.383e-30
Identity = 61/141 (43.26%), Postives = 92/141 (65.25%), Query Frame = 2

Query:  101 RLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKV--VSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGME-NSQGQISYEDFV 514
            +LTE ++ +  E F+LFD  GD  I  K++G V+R+LG NPTEAE++    N  D   +  I  P + ++M +K+      +E  E F+VFDKDGNG ISAAELRH++T +GE+L + EVD ++   + +  GQ++YE+FV
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM-INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of Essential myosin light chain vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304963)

HSP 1 Score: 110.923 bits (276), Expect = 6.383e-30
Identity = 61/141 (43.26%), Postives = 92/141 (65.25%), Query Frame = 2

Query:  101 RLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKV--VSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGME-NSQGQISYEDFV 514
            +LTE ++ +  E F+LFD  GD  I  K++G V+R+LG NPTEAE++    N  D   +  I  P + ++M +K+      +E  E F+VFDKDGNG ISAAELRH++T +GE+L + EVD ++   + +  GQ++YE+FV
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM-INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of Essential myosin light chain vs. Ensembl Zebrafish
Match: myl6 (myosin, light chain 6, alkali, smooth muscle and non-muscle [Source:ZFIN;Acc:ZDB-GENE-041010-28])

HSP 1 Score: 134.035 bits (336), Expect = 1.092e-38
Identity = 70/149 (46.98%), Postives = 97/149 (65.10%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERIS-----FEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIM 526
            M+  TE ++ +  E F LFD  GD KI   Q G+V+RALG NP  AE+ K   N  +E ++     FE F+P+ Q++ K K     ++FVEG +VFDK+GNG +  AELRH+LT +GE++ E EV+ LLAG E++ G I+YE FV HIM
Sbjct:    1 MSDFTEDQICEFKEAFLLFDRTGDGKIMYNQCGDVMRALGQNPVNAEVLKVLGNPSNEDMNMKMLDFEQFLPMLQAIAKNKDQGSFEDFVEGLRVFDKEGNGTVMGAELRHVLTTLGEKMTEEEVETLLAGHEDANGCINYEAFVRHIM 149

[Close]

BLAST of Essential myosin light chain vs. Ensembl Zebrafish
Match: CR381567.1 (pep chromosome:GRCz11:CHR_ALT_CTG23_1_29:28397866:28403409:1 gene:ENSDARG00000111021.1 transcript:ENSDART00000192911.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR381567.1)

HSP 1 Score: 133.265 bits (334), Expect = 3.013e-38
Identity = 70/156 (44.87%), Postives = 100/156 (64.10%), Query Frame = 2

Query:   77 IYFLLKMARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERIS-----FEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            +   LK +  +E ++ +  E F LFD  GD KI   Q G+V+RALG NP  AE+ K   N + E ++     FE F+P+ Q++ K K     ++FVEG +VFDK+GNG +  AELRH+LT +GE++ E EV+ LLAG E++ G I+YE FV HIM+
Sbjct:    1 MSLCLKQSDFSEDQILEFKEAFLLFDRTGDGKITYNQCGDVMRALGQNPVNAEVLKVLGNPKAEEMNHKLLDFEQFLPMLQAIAKNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLTTLGEKMTEEEVETLLAGHEDANGCINYEAFVRHIMS 156

[Close]

BLAST of Essential myosin light chain vs. Ensembl Zebrafish
Match: myl6 (myosin, light chain 6, alkali, smooth muscle and non-muscle [Source:ZFIN;Acc:ZDB-GENE-041010-28])

HSP 1 Score: 132.109 bits (331), Expect = 6.280e-38
Identity = 69/146 (47.26%), Postives = 95/146 (65.07%), Query Frame = 2

Query:  104 LTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERIS-----FEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIM 526
             TE ++ +  E F LFD  GD KI   Q G+V+RALG NP  AE+ K   N  +E ++     FE F+P+ Q++ K K     ++FVEG +VFDK+GNG +  AELRH+LT +GE++ E EV+ LLAG E++ G I+YE FV HIM
Sbjct:    4 FTEDQICEFKEAFLLFDRTGDGKIMYNQCGDVMRALGQNPVNAEVLKVLGNPSNEDMNMKMLDFEQFLPMLQAIAKNKDQGSFEDFVEGLRVFDKEGNGTVMGAELRHVLTTLGEKMTEEEVETLLAGHEDANGCINYEAFVRHIM 149

[Close]

BLAST of Essential myosin light chain vs. Ensembl Zebrafish
Match: zgc:153867 (zgc:153867 [Source:ZFIN;Acc:ZDB-GENE-030131-9170])

HSP 1 Score: 131.724 bits (330), Expect = 7.701e-38
Identity = 69/150 (46.00%), Postives = 98/150 (65.33%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERIS-----FEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            M+  +E ++ +  E F LFD  GD KI   Q G+V+RALG NP  AE+ K   N + E ++     FE F+P+ Q++ K K     ++FVEG +VFDK+GNG +  AELRH+LT +GE++ E EV+ LLAG E++ G I+YE FV HIM+
Sbjct:    1 MSDFSEDQILEFKEAFLLFDRTGDGKITYNQCGDVMRALGQNPVNAEVLKVLGNPKAEEMNHKLLDFEQFLPMLQAIAKNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLTTLGEKMTEEEVETLLAGHEDANGCINYEAFVRHIMS 150

[Close]

BLAST of Essential myosin light chain vs. Ensembl Zebrafish
Match: myl6 (myosin, light chain 6, alkali, smooth muscle and non-muscle [Source:ZFIN;Acc:ZDB-GENE-041010-28])

HSP 1 Score: 128.642 bits (322), Expect = 1.378e-36
Identity = 67/150 (44.67%), Postives = 97/150 (64.67%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERIS-----FEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            M+  TE ++ +  E F LFD  GD KI   Q G+V+RALG NP  AE+ K   N  +E ++     FE F+P+ Q++ K K     ++FVEG +VFDK+GNG +  AELRH+LT +GE++ E EV+ LLAG E++ G I+YE+ V  +M+
Sbjct:    1 MSDFTEDQICEFKEAFLLFDRTGDGKIMYNQCGDVMRALGQNPVNAEVLKVLGNPSNEDMNMKMLDFEQFLPMLQAIAKNKDQGSFEDFVEGLRVFDKEGNGTVMGAELRHVLTTLGEKMTEEEVETLLAGHEDANGCINYEELVRMVMS 150

[Close]

BLAST of Essential myosin light chain vs. Ensembl Xenopus
Match: myl1 (myosin light chain 1 [Source:NCBI gene;Acc:394551])

HSP 1 Score: 141.739 bits (356), Expect = 1.565e-41
Identity = 73/143 (51.05%), Postives = 96/143 (67.13%), Query Frame = 2

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            E+ D  E F LFD  GDSKI   Q+ +V+RALG NPT AE+KK   N   E     +I FE F+P+ Q++   K     ++FVEG +VFDK+GNG +  AELRH+L  +GE++RE EV+ALLAG E+S G I+YE FV HIM+
Sbjct:    7 EVADFKEAFLLFDRTGDSKIALNQVADVMRALGQNPTNAEVKKVLGNPSAEEMNAKKIEFEQFLPMMQAVANNKDQGSFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMREEEVEALLAGQEDSNGCINYEAFVKHIMS 149

[Close]

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            E+ D  E F LFD  GDSKI   Q+ +V+RALG NPT AE+KK   N   E     +I FE F+P+ Q++   K     ++FVEG +VFDK+GNG +  AELRH+L  +GE++RE EV+ALLAG E+S G I+YE FV HIM+
Sbjct:    7 EVADFKEAFLLFDRTGDSKIALNQVADVMRALGQNPTNAEVKKVLGNPSAEEMNAKKIEFEQFLPMMQAVANNKDQGSFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMREEEVEALLAGQEDSNGCINYEAFVKHIMS 149

[Close]

BLAST of Essential myosin light chain vs. Ensembl Xenopus
Match: myl1 (myosin light chain 1 [Source:NCBI gene;Acc:394551])

HSP 1 Score: 141.739 bits (356), Expect = 5.380e-41
Identity = 73/143 (51.05%), Postives = 96/143 (67.13%), Query Frame = 2

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            E+ D  E F LFD  GDSKI   Q+ +V+RALG NPT AE+KK   N   E     +I FE F+P+ Q++   K     ++FVEG +VFDK+GNG +  AELRH+L  +GE++RE EV+ALLAG E+S G I+YE FV HIM+
Sbjct:   46 EVADFKEAFLLFDRTGDSKIALNQVADVMRALGQNPTNAEVKKVLGNPSAEEMNAKKIEFEQFLPMMQAVANNKDQGSFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMREEEVEALLAGQEDSNGCINYEAFVKHIMS 188

[Close]

BLAST of Essential myosin light chain vs. Ensembl Xenopus
Match: myl1 (myosin light chain 1 [Source:NCBI gene;Acc:394551])

HSP 1 Score: 139.813 bits (351), Expect = 1.016e-40
Identity = 71/137 (51.82%), Postives = 93/137 (67.88%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            E F LFD  GDSKI   Q+ +V+RALG NPT AE+KK   N   E     +I FE F+P+ Q++   K     ++FVEG +VFDK+GNG +  AELRH+L  +GE++RE EV+ALLAG E+S G I+YE FV HIM+
Sbjct:   14 EAFLLFDRTGDSKIALNQVADVMRALGQNPTNAEVKKVLGNPSAEEMNAKKIEFEQFLPMMQAVANNKDQGSFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMREEEVEALLAGQEDSNGCINYEAFVKHIMS 150

[Close]

BLAST of Essential myosin light chain vs. Ensembl Xenopus
Match: myl1 (myosin light chain 1 [Source:NCBI gene;Acc:394551])

HSP 1 Score: 140.584 bits (353), Expect = 1.455e-40
Identity = 72/141 (51.06%), Postives = 95/141 (67.38%), Query Frame = 2

Query:  122 NDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            +D  E F LFD  GDSKI   Q+ +V+RALG NPT AE+KK   N   E     +I FE F+P+ Q++   K     ++FVEG +VFDK+GNG +  AELRH+L  +GE++RE EV+ALLAG E+S G I+YE FV HIM+
Sbjct:   49 DDFKEAFLLFDRTGDSKIALNQVADVMRALGQNPTNAEVKKVLGNPSAEEMNAKKIEFEQFLPMMQAVANNKDQGSFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMREEEVEALLAGQEDSNGCINYEAFVKHIMS 189

[Close]

BLAST of Essential myosin light chain vs. Ensembl Mouse
Match: Myl1 (myosin, light polypeptide 1 [Source:MGI Symbol;Acc:MGI:97269])

HSP 1 Score: 139.813 bits (351), Expect = 7.550e-41
Identity = 70/143 (48.95%), Postives = 97/143 (67.83%), Query Frame = 2

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            ++ D  E F LFD  G+ KI   Q+G+V+RALG NPT AE+KK   N  +E     +I FE F+P+ Q++   K     ++FVEG +VFDK+GNG +  AELRH+L  +GE+++E EV+ALLAG E+S G I+YE FV HIM+
Sbjct:    7 QIADFKEAFLLFDRTGECKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIEFEQFLPMMQAISNNKDQGGYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALLAGQEDSNGCINYEAFVKHIMS 149

[Close]

BLAST of Essential myosin light chain vs. Ensembl Mouse
Match: Myl1 (myosin, light polypeptide 1 [Source:MGI Symbol;Acc:MGI:97269])

HSP 1 Score: 139.043 bits (349), Expect = 3.572e-40
Identity = 70/140 (50.00%), Postives = 95/140 (67.86%), Query Frame = 2

Query:  125 DALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            D  E F LFD  G+ KI   Q+G+V+RALG NPT AE+KK   N  +E     +I FE F+P+ Q++   K     ++FVEG +VFDK+GNG +  AELRH+L  +GE+++E EV+ALLAG E+S G I+YE FV HIM+
Sbjct:   48 DFKEAFLLFDRTGECKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIEFEQFLPMMQAISNNKDQGGYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALLAGQEDSNGCINYEAFVKHIMS 187

[Close]

BLAST of Essential myosin light chain vs. Ensembl Mouse
Match: Myl1 (myosin, light polypeptide 1 [Source:MGI Symbol;Acc:MGI:97269])

HSP 1 Score: 129.413 bits (324), Expect = 1.155e-36
Identity = 65/135 (48.15%), Postives = 91/135 (67.41%), Query Frame = 2

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYE 505
            ++ D  E F LFD  G+ KI   Q+G+V+RALG NPT AE+KK   N  +E     +I FE F+P+ Q++   K     ++FVEG +VFDK+GNG +  AELRH+L  +GE+++E EV+ALLAG E+S G I+YE
Sbjct:    7 QIADFKEAFLLFDRTGECKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIEFEQFLPMMQAISNNKDQGGYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALLAGQEDSNGCINYE 141

[Close]

BLAST of Essential myosin light chain vs. Ensembl Mouse
Match: Myl6 (myosin, light polypeptide 6, alkali, smooth muscle and non-muscle [Source:MGI Symbol;Acc:MGI:109318])

HSP 1 Score: 128.257 bits (321), Expect = 2.164e-36
Identity = 68/150 (45.33%), Postives = 95/150 (63.33%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKC-GYNNQDER----ISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            M   TE +  +  E F LFD  GD KI   Q G+V+RALG NPT AE+ K  G    DE     + FE F+P+ Q++ K K     +++VEG +VFDK+GNG +  AE+RH+L  +GE++ E EV+ L+AG E+S G I+YE FV HI++
Sbjct:    1 MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILS 150

[Close]

BLAST of Essential myosin light chain vs. Ensembl Mouse
Match: Myl6b (myosin, light polypeptide 6B [Source:MGI Symbol;Acc:MGI:1917789])

HSP 1 Score: 129.028 bits (323), Expect = 5.019e-36
Identity = 64/143 (44.76%), Postives = 96/143 (67.13%), Query Frame = 2

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            +L +  E F LFD  GD KI   Q G+++RALG NPT AE+ K   N ++E     R+ FE F+P+ Q++ K +     ++++EG +VFDK+GNG +  AELRH+LT +GE++ E EV+ +LAG E+S G I+YE F+ HI++
Sbjct:   64 QLEEFREAFELFDRVGDGKILYSQCGDLMRALGQNPTNAEVLKVLGNPKNEELKSRRVDFETFLPMLQAVAKNRDQGTYEDYLEGLRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGHEDSNGCINYEAFLKHILS 206

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BLAST of Essential myosin light chain vs. UniProt/SwissProt
Match: sp|P54357|MLC2_DROME (Myosin-2 essential light chain OS=Drosophila melanogaster OX=7227 GN=Mlc-c PE=1 SV=1)

HSP 1 Score: 162.155 bits (409), Expect = 8.436e-49
Identity = 77/146 (52.74%), Postives = 106/146 (72.60%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYN-NQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            MA  TE +L +  E F LFD +GD KI+  Q+GE +RALG NPTE+++KKC +    DERISFE+F+PIYQ++ K +      +F+EG + FDKD +G IS+AELRHLLT +GE+L + EV+ LLA ME+ QG I+YE+FV  +M+
Sbjct:    1 MAAYTEDQLAEFQEAFNLFDNRGDGKIQLSQVGECLRALGQNPTESDVKKCTHQLKPDERISFEVFLPIYQAISKARSGDTADDFIEGLRHFDKDASGYISSAELRHLLTTLGEKLTDEEVEQLLANMEDQQGNINYEEFVRMVMS 146

[Close]

BLAST of Essential myosin light chain vs. UniProt/SwissProt
Match: sp|Q9XVI9|MLC5_CAEEL (Myosin-2 essential light chain OS=Caenorhabditis elegans OX=6239 GN=mlc-5 PE=1 SV=1)

HSP 1 Score: 156.377 bits (394), Expect = 1.191e-46
Identity = 75/139 (53.96%), Postives = 101/139 (72.66%), Query Frame = 2

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKC-GYNNQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            +L D  E FA FD+KGD +I  +Q+G+V+RALG NPTEAEI KC G  +++ R+SFE F+PI+QS+ K +     +EFVEG   FDK+GNGMI+ AELRHLLT +GERL + +VD LL+G  +S G ++  DFV  +MN
Sbjct:    3 DLADCREVFAYFDSKGDERISVQQVGDVLRALGQNPTEAEIHKCVGSFDREARLSFEDFVPIFQSVSKNREKHTVEEFVEGLSHFDKEGNGMINVAELRHLLTTLGERLSDEDVDQLLSGHNDSHGNVNISDFVRAVMN 141

[Close]

BLAST of Essential myosin light chain vs. UniProt/SwissProt
Match: sp|P05976|MYL1_HUMAN (Myosin light chain 1/3, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=MYL1 PE=1 SV=3)

HSP 1 Score: 141.739 bits (356), Expect = 3.156e-40
Identity = 69/137 (50.36%), Postives = 96/137 (70.07%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            E F LFD  GDSKI   Q+G+V+RALG NPT AE++K   N  +E     +I FE F+P+ Q++   K  +  ++FVEG +VFDK+GNG +  AELRH+L  +GE+++E EV+AL+AG E+S G I+YE FV HIM+
Sbjct:   57 EAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMS 193

[Close]

BLAST of Essential myosin light chain vs. UniProt/SwissProt
Match: sp|P02602|MYL1_RABIT (Myosin light chain 1/3, skeletal muscle isoform OS=Oryctolagus cuniculus OX=9986 GN=MYL1 PE=1 SV=3)

HSP 1 Score: 140.969 bits (354), Expect = 6.246e-40
Identity = 69/137 (50.36%), Postives = 95/137 (69.34%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            E F L+D  GDSKI   Q+G+V+RALG NPT AE+KK   N  +E     +I FE F+P+ Q++   K     ++FVEG +VFDK+GNG +  AELRH+L  +GE+++E EV+AL+AG E+S G I+YE FV HIM+
Sbjct:   55 EAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMS 191

[Close]

BLAST of Essential myosin light chain vs. UniProt/SwissProt
Match: sp|P05977|MYL1_MOUSE (Myosin light chain 1/3, skeletal muscle isoform OS=Mus musculus OX=10090 GN=Myl1 PE=1 SV=2)

HSP 1 Score: 139.043 bits (349), Expect = 2.499e-39
Identity = 70/140 (50.00%), Postives = 95/140 (67.86%), Query Frame = 2

Query:  125 DALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            D  E F LFD  G+ KI   Q+G+V+RALG NPT AE+KK   N  +E     +I FE F+P+ Q++   K     ++FVEG +VFDK+GNG +  AELRH+L  +GE+++E EV+ALLAG E+S G I+YE FV HIM+
Sbjct:   48 DFKEAFLLFDRTGECKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIEFEQFLPMMQAISNNKDQGGYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALLAGQEDSNGCINYEAFVKHIMS 187

[Close]

BLAST of Essential myosin light chain vs. TrEMBL
Match: Q26572 (Essential myosin light chain OS=Schistosoma mansoni OX=6183 GN=Smp_062250.1 PE=2 SV=1)

HSP 1 Score: 195.282 bits (495), Expect = 2.829e-59
Identity = 94/146 (64.38%), Postives = 118/146 (80.82%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGY-NNQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            M  L+E +LND  E F LFDTKGD KIEAK IGEVVRA+GLNPTE++I K GY NN +ERISFE F+PIY  L+K++V  D + F+E F+VFDK+ NG+ISAAELRHLLTA+GE+LR++EVD LL+G+ENSQG + YE FV  +M+
Sbjct:    1 MVDLSEKDLNDVHEMFLLFDTKGDEKIEAKDIGEVVRAMGLNPTESDIGKYGYQNNPNERISFESFVPIYHGLLKEQVEVDQETFIESFRVFDKEDNGLISAAELRHLLTALGEKLRDNEVDVLLSGLENSQGLVPYEAFVQRVMS 146

[Close]

BLAST of Essential myosin light chain vs. TrEMBL
Match: A0A5J4NHG8 (Myosin light chain 6 OS=Paragonimus westermani OX=34504 GN=DEA37_0011313 PE=4 SV=1)

HSP 1 Score: 192.586 bits (488), Expect = 2.900e-58
Identity = 96/147 (65.31%), Postives = 119/147 (80.95%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQ---DERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIM 526
            M  L E +L +A +TFALFDT GD KIEAK IGEVVRALGLNPTE++++K  ++NQ   +ERI+FE+F+PIYQ+L K++   +P+EF+EGF+VFDKD NG ISAAELRHLLTA+GERLRE EVD LLAGMEN QG + YE FV  I+
Sbjct:    1 MYELREKDLQEARDTFALFDTVGDEKIEAKDIGEVVRALGLNPTESDVRK--FSNQTDANERITFEMFLPIYQALSKEQKDINPEEFIEGFRVFDKDSNGFISAAELRHLLTALGERLREDEVDQLLAGMENGQGLVPYEAFVQRIL 145

[Close]

BLAST of Essential myosin light chain vs. TrEMBL
Match: A0A564YIC3 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS6774 PE=4 SV=1)

HSP 1 Score: 188.348 bits (477), Expect = 1.207e-56
Identity = 92/146 (63.01%), Postives = 115/146 (78.77%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQ-DERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            MA L E +L DA E F+LF T  D KIEA+ IG++VRALGL PTEA+I K G+ ++  ERISFE F+PIYQ L+K+K  ++P+EF+EGFKVFDK+ NG+ISAAELRHLLT +GERL E EVD LL+GME+ QGQ+ YE+FV  IM 
Sbjct:    1 MADLPEKDLQDARELFSLFATGEDEKIEARYIGDLVRALGLVPTEAQIAKFGFKDKPSERISFETFLPIYQGLLKEKKTNNPEEFIEGFKVFDKESNGLISAAELRHLLTQLGERLTEKEVDVLLSGMEDGQGQVPYEEFVRRIMT 146

[Close]

BLAST of Essential myosin light chain vs. TrEMBL
Match: A0A0R3WAW4 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS7726 PE=4 SV=1)

HSP 1 Score: 188.348 bits (477), Expect = 1.247e-56
Identity = 95/146 (65.07%), Postives = 114/146 (78.08%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQD-ERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            MA L E EL DA E FALF T  D KIEA+ IG++VRALGL PTEA+I K GY ++  ERISFE F+PI+Q LMK+K  ++ +EF+EGFKVFDK+ NG+ISAAELRHLLT +GERL E EVD LLAGME+ QGQ+ YE FV  IM+
Sbjct:    1 MADLPEKELQDARELFALFSTGEDEKIEARYIGDLVRALGLVPTEAQIAKFGYKDKPTERISFETFLPIFQGLMKEKKPNNQEEFIEGFKVFDKESNGLISAAELRHLLTQLGERLTEKEVDVLLAGMEDGQGQVPYEAFVRRIMS 146

[Close]

BLAST of Essential myosin light chain vs. TrEMBL
Match: A0A0R3U3G0 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS1100 PE=4 SV=2)

HSP 1 Score: 187.963 bits (476), Expect = 2.033e-56
Identity = 93/146 (63.70%), Postives = 115/146 (78.77%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQ-DERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            MA L E EL DA E FALF T  D KIEA+ IG++VRALGL PTEA+I K G+ ++  ERI+FE F+PIYQ LMK+K  ++P+EF+EGF+VFDK+ NG ISAAELRHLLT +GERLR+ EVD LL+GME+ QGQ+ YE FV  IM+
Sbjct:    1 MADLPEKELQDARELFALFATGEDEKIEARYIGDLVRALGLIPTEAQIAKYGFKDKPSERITFETFLPIYQGLMKEKKPNNPEEFIEGFRVFDKEANGYISAAELRHLLTQLGERLRKDEVDILLSGMEDGQGQVPYEAFVKRIMS 146

[Close]

BLAST of Essential myosin light chain vs. Ensembl Cavefish
Match: zgc:153867 (zgc:153867 [Source:ZFIN;Acc:ZDB-GENE-030131-9170])

HSP 1 Score: 131.724 bits (330), Expect = 7.768e-38
Identity = 67/137 (48.91%), Postives = 91/137 (66.42%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERIS-----FEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            E F LFD  GD KI   Q G+V+RALG NP  AE+ K   N + E ++     FE F+P+ Q++ K K     ++FVEG +VFDK+GNG +  AELRH+LT +GE++ E EV+ LLAG E++ G I+YE FV HIM+
Sbjct:   13 EAFLLFDRTGDGKISYSQCGDVMRALGQNPVNAEVLKVLGNPKAEEMNHKMLDFEQFLPMLQAIAKNKDQGSFEDFVEGLRVFDKEGNGTVMGAELRHVLTTLGEKMTEDEVETLLAGHEDANGCINYEAFVRHIMS 149

[Close]

BLAST of Essential myosin light chain vs. Ensembl Cavefish
Match: myl6 (myosin light polypeptide 6 [Source:NCBI gene;Acc:103021650])

HSP 1 Score: 130.954 bits (328), Expect = 1.283e-37
Identity = 68/149 (45.64%), Postives = 97/149 (65.10%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERIS-----FEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIM 526
            M+  +E ++++  E F LFD  GD KI   Q G+V+RALG NP  AE+ K   N + E ++     FE F+P+ Q++ K K     ++FVEG +VFDK+GNG +  AELRH+LT +GE++ E EV+ LLAG E++ G I+YE FV  IM
Sbjct:    1 MSDFSEDQISEFKEAFLLFDRTGDGKISYSQCGDVMRALGQNPVNAEVLKVLGNPKAEEMNIKMLDFEQFLPMLQAIAKNKDQGSFEDFVEGLRVFDKEGNGTVMGAELRHVLTTLGEKMTEEEVETLLAGHEDANGCINYEAFVRQIM 149

[Close]

BLAST of Essential myosin light chain vs. Ensembl Cavefish
Match: myl6 (myosin light polypeptide 6 [Source:NCBI gene;Acc:103021650])

HSP 1 Score: 129.028 bits (323), Expect = 9.128e-37
Identity = 66/150 (44.00%), Postives = 98/150 (65.33%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERIS-----FEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            M+  +E ++++  E F LFD  GD KI   Q G+V+RALG NP  AE+ K   N + E ++     FE F+P+ Q++ K K     ++FVEG +VFDK+GNG +  AELRH+LT +GE++ E EV+ LLAG E++ G I+YE+ V  +M+
Sbjct:    1 MSDFSEDQISEFKEAFLLFDRTGDGKISYSQCGDVMRALGQNPVNAEVLKVLGNPKAEEMNIKMLDFEQFLPMLQAIAKNKDQGSFEDFVEGLRVFDKEGNGTVMGAELRHVLTTLGEKMTEEEVETLLAGHEDANGCINYEELVRMVMS 150

[Close]

BLAST of Essential myosin light chain vs. Ensembl Cavefish
Match: myl1 (myosin light chain 1, skeletal muscle isoform [Source:NCBI gene;Acc:103022703])

HSP 1 Score: 125.561 bits (314), Expect = 5.781e-35
Identity = 63/147 (42.86%), Postives = 94/147 (63.95%), Query Frame = 2

Query:  104 LTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQ-----DERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
             T  +L D  E F LFD  GD+K+   QI +++RALG NPT  E+ K   N       ++R+ FE F+P+ Q ++        +++VEG +VFDK+GNG +  AELR +L+ +GE++ E+EVDAL+AG E+  G ++YE FV HIM+
Sbjct:   44 FTPDQLEDYREAFGLFDRVGDNKVAFNQIADIMRALGQNPTNKEVNKILGNPSADDMANKRVEFEQFLPMLQFVVNSPNKGTFEDYVEGLRVFDKEGNGTVMGAELRIVLSTLGEKMSEAEVDALMAGQEDENGCVNYEAFVKHIMS 190

[Close]

BLAST of Essential myosin light chain vs. Ensembl Cavefish
Match: myl1 (myosin light chain 1, skeletal muscle isoform [Source:NCBI gene;Acc:103022703])

HSP 1 Score: 123.635 bits (309), Expect = 3.258e-34
Identity = 62/146 (42.47%), Postives = 93/146 (63.70%), Query Frame = 2

Query:  107 TEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQ-----DERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
             EM  +   E F LFD  GD+K+   QI +++RALG NPT  E+ K   N       ++R+ FE F+P+ Q ++        +++VEG +VFDK+GNG +  AELR +L+ +GE++ E+EVDAL+AG E+  G ++YE FV HIM+
Sbjct:   42 VEMHTDLPQEAFGLFDRVGDNKVAFNQIADIMRALGQNPTNKEVNKILGNPSADDMANKRVEFEQFLPMLQFVVNSPNKGTFEDYVEGLRVFDKEGNGTVMGAELRIVLSTLGEKMSEAEVDALMAGQEDENGCVNYEAFVKHIMS 187

[Close]

BLAST of Essential myosin light chain vs. Ensembl Sea Lamprey
Match: cmlc1 (cardiac myosin light chain-1 [Source:ZFIN;Acc:ZDB-GENE-030522-1])

HSP 1 Score: 125.176 bits (313), Expect = 4.504e-36
Identity = 62/146 (42.47%), Postives = 93/146 (63.70%), Query Frame = 2

Query:  104 LTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERI-----SFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIM 526
             T+ ++ +  E F+LFD  G+ KI   Q G+++RALG NPT  ++ K   N + E +      F+ F+P+ Q++ K K     ++FVEG +VFDK+GNG +  AELRH+L  +GERL E EV+ L+ G E+S G I+YE F+ HI+
Sbjct:    4 FTQDQIEEYREAFSLFDRTGEMKITYSQCGDIMRALGQNPTNCDVMKVLGNPKPEEMLVKTMDFDTFLPMMQAICKIKDQGSYEDFVEGLRVFDKEGNGRVMGAELRHVLATLGERLTEDEVEQLMTGQEDSSGCINYEAFIKHIL 149

[Close]

BLAST of Essential myosin light chain vs. Ensembl Sea Lamprey
Match: cmlc1 (cardiac myosin light chain-1 [Source:ZFIN;Acc:ZDB-GENE-030522-1])

HSP 1 Score: 125.561 bits (314), Expect = 1.086e-35
Identity = 63/136 (46.32%), Postives = 86/136 (63.24%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERI-----SFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIM 526
            E F+LFD  GD KI   Q G+V+RALG NPT AE+ K     + E +      FE F+P  Q +   K     ++FVEG +VFDK+GNG +  AELRH+L  +GE++ E EV+ L++G E+S G I+YE F+ HIM
Sbjct:   47 EAFSLFDRTGDVKITYSQCGDVMRALGQNPTNAEVLKVLNKPKPEEMLIKDMDFETFLPTLQHVANSKDRGTLEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEDEVEQLMSGQEDSNGDINYEAFIKHIM 182

[Close]

BLAST of Essential myosin light chain vs. Ensembl Sea Lamprey
Match: myl1 (myosin, light chain 1, alkali; skeletal, fast [Source:ZFIN;Acc:ZDB-GENE-030131-8109])

HSP 1 Score: 120.553 bits (301), Expect = 3.645e-34
Identity = 64/140 (45.71%), Postives = 88/140 (62.86%), Query Frame = 2

Query:  119 LNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQD-----ERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHI 523
            L D  E F+LFD  G+ KI   Q GEV+RALG NPT AE+ K   N +      + + FE F+P+ Q++ K K     ++FVEG +VFDK+GNG +  AELRH+L  +GER+ E EV+ LL G E++ G I+YE  V  +
Sbjct:    9 LPDFKEAFSLFDRTGEMKISYSQCGEVMRALGQNPTNAEVLKLLGNPKPAEMNVKMLEFEQFLPMLQTVSKSKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLCTLGERMSEEEVELLLVGQEDTNGLINYEAEVRQV 148

[Close]

BLAST of Essential myosin light chain vs. Ensembl Sea Lamprey
Match: CALML3 (calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:1452])

HSP 1 Score: 111.309 bits (277), Expect = 1.094e-30
Identity = 62/144 (43.06%), Postives = 92/144 (63.89%), Query Frame = 2

Query:  101 RLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLM--KQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGME-NSQGQISYEDFVHHI 523
            +LTE ++ +  E F+LFD  GD  I  K++G V+R+LG NPTEAE++    N  D   +  I  P + ++M  K K     +E  E F+VFDKDGNG ISAAELRH++T +GE+L + EVD ++   + +  GQ++YE+FV  +
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM-INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

[Close]

BLAST of Essential myosin light chain vs. Ensembl Sea Lamprey
Match: CALM3 (calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449])

HSP 1 Score: 111.309 bits (277), Expect = 1.256e-30
Identity = 62/144 (43.06%), Postives = 92/144 (63.89%), Query Frame = 2

Query:  101 RLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLM--KQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGME-NSQGQISYEDFVHHI 523
            +LTE ++ +  E F+LFD  GD  I  K++G V+R+LG NPTEAE++    N  D   +  I  P + ++M  K K     +E  E F+VFDKDGNG ISAAELRH++T +GE+L + EVD ++   + +  GQ++YE+FV  +
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM-INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

[Close]

BLAST of Essential myosin light chain vs. Ensembl Yeast
Match: CMD1 (Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability [Source:SGD;Acc:S000000313])

HSP 1 Score: 103.219 bits (256), Expect = 6.698e-28
Identity = 56/141 (39.72%), Postives = 93/141 (65.96%), Query Frame = 2

Query:   98 ARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKVVSDP--QEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFV 514
            + LTE ++ +  E FALFD   +  I + ++  V+R+LGL+P+EAE+     N  D   + +I    + +LM +++ S+   QE +E FKVFDK+G+G+ISAAEL+H+LT+IGE+L ++EVD +L  + +  G+I+ + F 
Sbjct:    3 SNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDL-MNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREVSDGSGEINIQQFA 142

[Close]

BLAST of Essential myosin light chain vs. Ensembl Yeast
Match: MLC1 (Essential light chain for Myo1p; light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition [Source:SGD;Acc:S000003074])

HSP 1 Score: 85.1149 bits (209), Expect = 6.488e-21
Identity = 44/139 (31.65%), Postives = 78/139 (56.12%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEI-------FIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGME-NSQGQISYEDFVHHIM 526
            + F LFD KG   I    +G+ +RA+G NPT   ++     +   R +  +        I + +  +     +  ++FV+ F+VFDK+  G +S  +LR++LT +GE+L ++EVD LL G+E +S G+I Y+ F+  ++
Sbjct:    9 DIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFIEDVL 147

[Close]

BLAST of Essential myosin light chain vs. Ensembl Yeast
Match: CDC31 (Calcium-binding component of the spindle pole body (SPB) half-bridge; required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation [Source:SGD;Acc:S000005783])

HSP 1 Score: 44.2838 bits (103), Expect = 3.721e-6
Identity = 35/141 (24.82%), Postives = 65/141 (46.10%), Query Frame = 2

Query:   98 ARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKVVSDP-QEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGME-NSQGQISYEDFV 514
            + L E +  +  E F+LFD   D  ++  ++   ++ALG    + EI         E      +   Y  + ++ +  DP  E    F++FD D  G IS   LR +   +GE L + E+ A++   + +  G+I+  +F+
Sbjct:   15 SELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFI 155

[Close]

BLAST of Essential myosin light chain vs. Ensembl Nematostella
Match: EDO37259 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG62])

HSP 1 Score: 143.28 bits (360), Expect = 9.852e-43
Identity = 71/148 (47.97%), Postives = 104/148 (70.27%), Query Frame = 2

Query:   95 MAR-LTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE---RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIM 526
            MA+ LT+ ++    E+F L+D +GD KI++ Q+GEV+R LG NPT AE+KK       E   RISFE F+P+YQS M +K     ++FV+  +VFD DG+GMI+  ELRH+LT +GE+L +SEVD+L+ G+E+ QGQI  E+F+  ++
Sbjct:    1 MAKNLTDKDIRQLRESFELYDKQGDEKIDSSQLGEVLRGLGQNPTNAEVKKIVSEMDPEGGNRISFEEFLPVYQSYMGKKPKFSTEDFVDSLRVFDNDGSGMINEGELRHILTTLGEKLTDSEVDSLIQGLEDKQGQIDCEEFILSVL 148

[Close]

BLAST of Essential myosin light chain vs. Ensembl Nematostella
Match: EDO44682 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV39])

HSP 1 Score: 143.28 bits (360), Expect = 1.072e-42
Identity = 73/145 (50.34%), Postives = 102/145 (70.34%), Query Frame = 2

Query:  119 LNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQD-----ERISFEIFIPIYQSLM---KQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            L D  E F L+D +GD +IE  Q+GEV+RAL +NPTE E++K   NN D     +R+SFE F P+YQ+L    +++   D   F+E FKVFD++GNG+I AAELRHLL ++G++L + EVD L+ G E++QGQ+ YEDFV  +MN
Sbjct:    7 LEDLKECFLLYDKRGDERIECSQVGEVLRALDVNPTEHEVQKI-VNNIDPAGEMKRVSFEEFYPMYQNLRERHRKERSVDVDYFMECFKVFDRNGNGLIGAAELRHLLASLGDKLSDEEVDNLMVGFEDNQGQVFYEDFVRAVMN 150

[Close]

BLAST of Essential myosin light chain vs. Ensembl Nematostella
Match: EDO44509 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVT6])

HSP 1 Score: 137.117 bits (344), Expect = 2.107e-40
Identity = 67/151 (44.37%), Postives = 104/151 (68.87%), Query Frame = 2

Query:   98 ARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE---RISFEIFIPIYQS----LMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            A+LTE ++ +  + F+++DT GD K+E+ Q+GEV+RA  LNPT  E++K       E   R+SF+ F P+YQS    + + K  SD  +FV+  KVFD DG+G ISA ELRH+LT+IGE+L + E D+L   +E +QGQ++YE+F+ ++++
Sbjct:    3 AQLTERQIAELTDVFSIYDTVGDGKVESAQLGEVMRAFDLNPTNVEVRKIIKEVDPEGTRRVSFDEFFPVYQSFKGKVARNKAKSD--DFVDSLKVFDSDGSGFISAGELRHVLTSIGEKLSDEEADSLFQAVEYNQGQVNYEEFIKYVLS 151

[Close]

BLAST of Essential myosin light chain vs. Ensembl Nematostella
Match: EDO49541 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGK2])

HSP 1 Score: 135.961 bits (341), Expect = 6.629e-40
Identity = 69/148 (46.62%), Postives = 99/148 (66.89%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE---RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            MA LTE ++ +  E F+LFD  GD KIE  QIG ++R+LGLNPT AE+KK   +   +   R+SFE F+PIY S  ++K      EFVEG +VFD+DG G + AAELR +L ++GE+L + EV  L A +++S G I+YE+ V  +++
Sbjct:    1 MAGLTEEQIGEYREAFSLFDRVGDGKIECDQIGCLLRSLGLNPTGAEVKKIEKDVDPKGIARVSFEEFLPIYTSAYQKKQTGSADEFVEGLRVFDRDGTGTVLAAELRSVLMSLGEKLSDEEVTTLFAPVDDSSGHINYEELVKVVLS 148

[Close]

BLAST of Essential myosin light chain vs. Ensembl Nematostella
Match: EDO46518 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPI8])

HSP 1 Score: 110.923 bits (276), Expect = 2.487e-30
Identity = 61/144 (42.36%), Postives = 93/144 (64.58%), Query Frame = 2

Query:  101 RLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKV--VSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGME-NSQGQISYEDFVHHI 523
            +LTE ++ +  E F+LFD  GD  I  K++G V+R+LG NPTEAE++    N  D   +  I  P + ++M +K+      +E  E F+VFDKDGNG ISAAELRH++T +GE+L + EVD ++   + +  GQ++YE+FV  +
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM-INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMM 146

[Close]

BLAST of Essential myosin light chain vs. Ensembl Medaka
Match: ENSORLT00000040794.1 (myosin light polypeptide 6 [Source:NCBI gene;Acc:101167617])

HSP 1 Score: 133.265 bits (334), Expect = 1.714e-38
Identity = 68/150 (45.33%), Postives = 99/150 (66.00%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERIS-----FEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            M+  +E ++ +  E F LFD  GD KI   Q G+V+RALG NP  AE+ K   N + E ++     FE F+P++Q++ K K     ++FVEG +VFDK+GNG +  AELRH+LT +GE++ E EV+ LLAG E++ G I+YE FV HI++
Sbjct:    1 MSDFSEDQIIEFKEAFLLFDRTGDGKISYSQCGDVMRALGQNPVNAEVLKVLGNPKAEEMNTKMLDFEQFLPMFQAIAKNKDQGSMEDFVEGLRVFDKEGNGTVMGAELRHVLTTLGEKMTEEEVETLLAGHEDANGCINYEAFVRHILS 150

[Close]

BLAST of Essential myosin light chain vs. Ensembl Medaka
Match: ENSORLT00000009354.2 (myosin light polypeptide 6 [Source:NCBI gene;Acc:101167617])

HSP 1 Score: 132.109 bits (331), Expect = 3.031e-37
Identity = 66/137 (48.18%), Postives = 92/137 (67.15%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERIS-----FEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            E F LFD  GD KI   Q G+V+RALG NP  AE+ K   N + E ++     FE F+P++Q++ K K     ++FVEG +VFDK+GNG +  AELRH+LT +GE++ E EV+ LLAG E++ G I+YE FV HI++
Sbjct:   72 EAFLLFDRTGDGKISYSQCGDVMRALGQNPVNAEVLKVLGNPKAEEMNTKMLDFEQFLPMFQAIAKNKDQGSMEDFVEGLRVFDKEGNGTVMGAELRHVLTTLGEKMTEEEVETLLAGHEDANGCINYEAFVRHILS 208

[Close]

BLAST of Essential myosin light chain vs. Ensembl Medaka
Match: myl1 (myosin light chain 1, skeletal muscle isoform [Source:NCBI gene;Acc:101167500])

HSP 1 Score: 127.872 bits (320), Expect = 8.751e-36
Identity = 62/143 (43.36%), Postives = 94/143 (65.73%), Query Frame = 2

Query:  116 ELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            ++ D  E F LFD  GD+K+   QI +++RALG NPT  E+ K   N   E     R+ FE F+P+ Q+++     +  +++VEG +VFDK+GNG +  AELR +L+ +GE++ E+E+DAL+AG E+  G I+YE FV HIM+
Sbjct:   49 QIEDYREAFGLFDRVGDNKVAYNQIADIMRALGQNPTNKEVNKLLGNPSTEDMASKRVEFESFLPMLQTIINSPNKAGFEDYVEGLRVFDKEGNGTVMGAELRIVLSTLGEKMNEAEIDALMAGQEDENGCINYEAFVKHIMS 191

[Close]

BLAST of Essential myosin light chain vs. Ensembl Medaka
Match: ENSORLT00000030160.1 (myosin light polypeptide 6 [Source:NCBI gene;Acc:101167617])

HSP 1 Score: 127.872 bits (320), Expect = 1.023e-35
Identity = 64/137 (46.72%), Postives = 91/137 (66.42%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERIS-----FEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            E F LFD  GD KI   Q G+V+RALG NP  AE+ K   N + E ++     FE F+P++Q++ K K     ++FVEG +VFDK+GNG +  AELRH+LT +GE++ E EV+ LLAG E++ G I+YE+ V  +M+
Sbjct:   72 EAFLLFDRTGDGKISYSQCGDVMRALGQNPVNAEVLKVLGNPKAEEMNTKMLDFEQFLPMFQAIAKNKDQGSMEDFVEGLRVFDKEGNGTVMGAELRHVLTTLGEKMTEEEVETLLAGHEDANGCINYEELVRMVMS 208

[Close]

BLAST of Essential myosin light chain vs. Ensembl Medaka
Match: myl1 (myosin light chain 1, skeletal muscle isoform [Source:NCBI gene;Acc:101167500])

HSP 1 Score: 127.102 bits (318), Expect = 1.463e-35
Identity = 62/140 (44.29%), Postives = 92/140 (65.71%), Query Frame = 2

Query:  125 DALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDE-----RISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            D  E F LFD  GD+K+   QI +++RALG NPT  E+ K   N   E     R+ FE F+P+ Q+++     +  +++VEG +VFDK+GNG +  AELR +L+ +GE++ E+E+DAL+AG E+  G I+YE FV HIM+
Sbjct:   54 DYREAFGLFDRVGDNKVAYNQIADIMRALGQNPTNKEVNKLLGNPSTEDMASKRVEFESFLPMLQTIINSPNKAGFEDYVEGLRVFDKEGNGTVMGAELRIVLSTLGEKMNEAEIDALMAGQEDENGCINYEAFVKHIMS 193

[Close]

BLAST of Essential myosin light chain vs. Planmine SMEST
Match: SMESG000042179.1 (SMESG000042179.1)

HSP 1 Score: 298.901 bits (764), Expect = 1.169e-103
Identity = 145/145 (100.00%), Postives = 145/145 (100.00%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 529
            MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN
Sbjct:    1 MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN 145

[Close]

BLAST of Essential myosin light chain vs. Planmine SMEST
Match: SMESG000034095.1 (SMESG000034095.1)

HSP 1 Score: 110.923 bits (276), Expect = 4.896e-30
Identity = 61/141 (43.26%), Postives = 92/141 (65.25%), Query Frame = 2

Query:  101 RLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKV--VSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGME-NSQGQISYEDFV 514
            +LTE ++ +  E F+LFD  GD  I  K++G V+R+LG NPTEAE++    N  D   +  I  P + ++M +K+      +E  E F+VFDKDGNG ISAAELRH++T +GE+L + EVD ++   + +  GQ++YE+FV
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM-INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of Essential myosin light chain vs. Planmine SMEST
Match: SMESG000010769.1 (SMESG000010769.1)

HSP 1 Score: 110.923 bits (276), Expect = 4.896e-30
Identity = 61/141 (43.26%), Postives = 92/141 (65.25%), Query Frame = 2

Query:  101 RLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQDERISFEIFIPIYQSLMKQKV--VSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLAGME-NSQGQISYEDFV 514
            +LTE ++ +  E F+LFD  GD  I  K++G V+R+LG NPTEAE++    N  D   +  I  P + ++M +K+      +E  E F+VFDKDGNG ISAAELRH++T +GE+L + EVD ++   + +  GQ++YE+FV
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM-INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of Essential myosin light chain vs. Planmine SMEST
Match: SMESG000075512.1 (SMESG000075512.1)

HSP 1 Score: 98.5969 bits (244), Expect = 3.987e-25
Identity = 54/151 (35.76%), Postives = 88/151 (58.28%), Query Frame = 2

Query:   95 MARLTEMELNDALETFALFDTKG--DSKIEAKQIGEVVRALGLNPTEAEIKKCGYNNQD--ERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLA---GMENSQGQISYEDFVHHIM 526
            M  L++ E+ D  E F LFD     D  ++A ++G+++R  G+NPT     K G   +   ++  FE F+PIY+ ++++K      +++E FK FD++G G IS AE+RH+LT  GE+L E E D +L      E+  G + YEDF+  ++
Sbjct:    1 MTALSKSEIEDIREVFDLFDFWDGRDGMVDALKVGDLLRCNGMNPTNRICIKHGATEKMGLKQYKFEEFVPIYEKIIQEKESGTFADYMEAFKTFDREGQGFISLAEMRHVLTMYGEKLSEEETDNILKFTDTHEDIDGNVKYEDFIKKVL 151

[Close]

BLAST of Essential myosin light chain vs. Planmine SMEST
Match: SMESG000042402.1 (SMESG000042402.1)

HSP 1 Score: 74.3294 bits (181), Expect = 3.810e-16
Identity = 46/137 (33.58%), Postives = 76/137 (55.47%), Query Frame = 2

Query:  134 ETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKKC---------GYNNQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMISAAELRHLLTAIGERLRESEVDALLA-GMENSQGQISYEDFV 514
            + F LFD   + KI +  +  V++ LG++P E E+  C         G+      I F+ F  +   +MK+   SD +E  + F+V DK+GNG I+A E+RH+LT + ++L + EVD ++    ++  G I+YE FV
Sbjct:   20 QAFLLFDKLNEGKISSSDLSMVLKCLGVDPNEIEMLDCLKELDPTGSGF------IEFDKFNSVIIRMMKEPF-SD-EELRDAFRVLDKEGNGFITATEIRHVLTNLCDKLTDEEVDEMIKEADDDGDGMINYEIFV 148

The following BLAST results are available for this feature:

BLAST of Essential myosin light chain vs. Ensembl Human
BLAST of Essential myosin light chain vs. Ensembl Celegans
BLAST of Essential myosin light chain vs. Ensembl Fly
BLAST of Essential myosin light chain vs. Ensembl Zebrafish
BLAST of Essential myosin light chain vs. Ensembl Xenopus
BLAST of Essential myosin light chain vs. Ensembl Mouse
BLAST of Essential myosin light chain vs. UniProt/SwissProt
BLAST of Essential myosin light chain vs. TrEMBL
BLAST of Essential myosin light chain vs. Ensembl Cavefish
BLAST of Essential myosin light chain vs. Ensembl Sea Lamprey
BLAST of Essential myosin light chain vs. Ensembl Yeast
BLAST of Essential myosin light chain vs. Ensembl Nematostella
BLAST of Essential myosin light chain vs. Ensembl Medaka
BLAST of Essential myosin light chain vs. Planmine SMEST

BLAST of Essential myosin light chain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MYL1	1.518e-41	50.36	myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:...	[more]
MYL1	6.572e-41	50.36	myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:...	[more]
MYL6B	1.090e-36	46.85	myosin light chain 6B [Source:HGNC Symbol;Acc:HGNC...	[more]
MYL6B	1.090e-36	46.85	myosin light chain 6B [Source:HGNC Symbol;Acc:HGNC...	[more]
MYL6	3.152e-36	45.33	myosin light chain 6 [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of Essential myosin light chain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mlc-5	9.360e-48	53.96	Myosin-2 essential light chain [Source:UniProtKB/...	[more]
mlc-5	9.360e-48	53.96	Myosin-2 essential light chain [Source:UniProtKB/...	[more]
mlc-3	1.722e-33	43.70	Myosin, essential light chain [Source:UniProtKB/S...	[more]
mlc-3	1.722e-33	43.70	Myosin, essential light chain [Source:UniProtKB/S...	[more]
cmd-1	4.669e-30	43.26	Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630...	[more]

BLAST of Essential myosin light chain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mlc-c	8.416e-50	52.74	gene:FBgn0004687 transcript:FBtr0070783	[more]
Mlc-c	1.073e-48	49.34	gene:FBgn0004687 transcript:FBtr0308579	[more]
Cam	6.383e-30	43.26	gene:FBgn0000253 transcript:FBtr0304964	[more]
Cam	6.383e-30	43.26	gene:FBgn0000253 transcript:FBtr0088001	[more]
Cam	6.383e-30	43.26	gene:FBgn0000253 transcript:FBtr0304963	[more]

BLAST of Essential myosin light chain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
myl6	1.092e-38	46.98	myosin, light chain 6, alkali, smooth muscle and n...	[more]
CR381567.1	3.013e-38	44.87	pep chromosome:GRCz11:CHR_ALT_CTG23_1_29:28397866:...	[more]
myl6	6.280e-38	47.26	myosin, light chain 6, alkali, smooth muscle and n...	[more]
zgc:153867	7.701e-38	46.00	zgc:153867 [Source:ZFIN;Acc:ZDB-GENE-030131-9170]	[more]
myl6	1.378e-36	44.67	myosin, light chain 6, alkali, smooth muscle and n...	[more]

BLAST of Essential myosin light chain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
myl1	1.565e-41	51.05	myosin light chain 1 [Source:NCBI gene;Acc:394551]	[more]
myl1	1.565e-41	51.05	myosin light chain 1 [Source:NCBI gene;Acc:394551]	[more]
myl1	5.380e-41	51.05	myosin light chain 1 [Source:NCBI gene;Acc:394551]	[more]
myl1	1.016e-40	51.82	myosin light chain 1 [Source:NCBI gene;Acc:394551]	[more]
myl1	1.455e-40	51.06	myosin light chain 1 [Source:NCBI gene;Acc:394551]	[more]

BLAST of Essential myosin light chain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Myl1	7.550e-41	48.95	myosin, light polypeptide 1 [Source:MGI Symbol;Acc...	[more]
Myl1	3.572e-40	50.00	myosin, light polypeptide 1 [Source:MGI Symbol;Acc...	[more]
Myl1	1.155e-36	48.15	myosin, light polypeptide 1 [Source:MGI Symbol;Acc...	[more]
Myl6	2.164e-36	45.33	myosin, light polypeptide 6, alkali, smooth muscle...	[more]
Myl6b	5.019e-36	44.76	myosin, light polypeptide 6B [Source:MGI Symbol;Ac...	[more]

BLAST of Essential myosin light chain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P54357\|MLC2_DROME	8.436e-49	52.74	Myosin-2 essential light chain OS=Drosophila melan...	[more]
sp\|Q9XVI9\|MLC5_CAEEL	1.191e-46	53.96	Myosin-2 essential light chain OS=Caenorhabditis e...	[more]
sp\|P05976\|MYL1_HUMAN	3.156e-40	50.36	Myosin light chain 1/3, skeletal muscle isoform OS...	[more]
sp\|P02602\|MYL1_RABIT	6.246e-40	50.36	Myosin light chain 1/3, skeletal muscle isoform OS...	[more]
sp\|P05977\|MYL1_MOUSE	2.499e-39	50.00	Myosin light chain 1/3, skeletal muscle isoform OS...	[more]

BLAST of Essential myosin light chain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q26572	2.829e-59	64.38	Essential myosin light chain OS=Schistosoma manson...	[more]
A0A5J4NHG8	2.900e-58	65.31	Myosin light chain 6 OS=Paragonimus westermani OX=...	[more]
A0A564YIC3	1.207e-56	63.01	Uncharacterized protein OS=Hymenolepis diminuta OX...	[more]
A0A0R3WAW4	1.247e-56	65.07	Uncharacterized protein OS=Taenia asiatica OX=6051...	[more]
A0A0R3U3G0	2.033e-56	63.70	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]

BLAST of Essential myosin light chain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
zgc:153867	7.768e-38	48.91	zgc:153867 [Source:ZFIN;Acc:ZDB-GENE-030131-9170]	[more]
myl6	1.283e-37	45.64	myosin light polypeptide 6 [Source:NCBI gene;Acc:1...	[more]
myl6	9.128e-37	44.00	myosin light polypeptide 6 [Source:NCBI gene;Acc:1...	[more]
myl1	5.781e-35	42.86	myosin light chain 1, skeletal muscle isoform [Sou...	[more]
myl1	3.258e-34	42.47	myosin light chain 1, skeletal muscle isoform [Sou...	[more]

BLAST of Essential myosin light chain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cmlc1	4.504e-36	42.47	cardiac myosin light chain-1 [Source:ZFIN;Acc:ZDB-...	[more]
cmlc1	1.086e-35	46.32	cardiac myosin light chain-1 [Source:ZFIN;Acc:ZDB-...	[more]
myl1	3.645e-34	45.71	myosin, light chain 1, alkali; skeletal, fast [Sou...	[more]
CALML3	1.094e-30	43.06	calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:145...	[more]
CALM3	1.256e-30	43.06	calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449]	[more]

BLAST of Essential myosin light chain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
CMD1	6.698e-28	39.72	Calmodulin; Ca2+ binding protein that regulates Ca...	[more]
MLC1	6.488e-21	31.65	Essential light chain for Myo1p; light chain for M...	[more]
CDC31	3.721e-6	24.82	Calcium-binding component of the spindle pole body...	[more]

BLAST of Essential myosin light chain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO37259	9.852e-43	47.97	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44682	1.072e-42	50.34	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44509	2.107e-40	44.37	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49541	6.629e-40	46.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46518	2.487e-30	42.36	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Essential myosin light chain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000040794.1	1.714e-38	45.33	myosin light polypeptide 6 [Source:NCBI gene;Acc:1...	[more]
ENSORLT00000009354.2	3.031e-37	48.18	myosin light polypeptide 6 [Source:NCBI gene;Acc:1...	[more]
myl1	8.751e-36	43.36	myosin light chain 1, skeletal muscle isoform [Sou...	[more]
ENSORLT00000030160.1	1.023e-35	46.72	myosin light polypeptide 6 [Source:NCBI gene;Acc:1...	[more]
myl1	1.463e-35	44.29	myosin light chain 1, skeletal muscle isoform [Sou...	[more]

BLAST of Essential myosin light chain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000042179.1	1.169e-103	100.00	SMESG000042179.1	[more]
SMESG000034095.1	4.896e-30	43.26	SMESG000034095.1	[more]
SMESG000010769.1	4.896e-30	43.26	SMESG000010769.1	[more]
SMESG000075512.1	3.987e-25	35.76	SMESG000075512.1	[more]
SMESG000042402.1	3.810e-16	33.58	SMESG000042402.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30007795 ID=SMED30007795|Name=Essential myosin light chain|organism=Schmidtea mediterranea sexual|type=transcript|length=864bp
GGTGTTTAAATGCATGCTCTGAATAATCTTTTGTTTGTGTAGTATAAATA
TTTGAATTTATCTTATTACTTTTCAAATATATTTCCTGTTAAAAATGGCA
CGATTGACTGAAATGGAACTCAATGATGCTTTAGAAACTTTTGCTTTATT
TGATACAAAAGGTGACAGCAAGATTGAAGCAAAGCAGATAGGTGAAGTTG
TGAGGGCTCTTGGTTTAAACCCAACTGAAGCTGAAATTAAAAAATGTGGA
TATAATAATCAAGATGAACGAATCTCATTTGAAATATTCATTCCAATTTA
CCAAAGTTTAATGAAACAGAAGGTGGTTTCAGATCCTCAAGAGTTTGTTG
AAGGTTTCAAAGTATTTGACAAAGACGGCAATGGAATGATAAGCGCGGCT
GAATTAAGACATTTATTGACTGCAATTGGAGAAAGATTACGTGAAAGCGA
AGTTGATGCTTTATTAGCTGGAATGGAAAATTCTCAAGGCCAGATTAGTT
ACGAAGATTTCGTTCACCACATCATGAATTGAGCAACTGACATTCCTGAA
TCTAATTTGAGCACTGCACCGGGCGTTTGTGTGCTAATTTCTGTGCTTAT
CGATTGAAATTTCAATACTAATTAGCCTTATTTTTTGAAATTATTTCCAT
TATAATAATATCTTTAAATGTATTTTACCGGTTTAATAAACTATAAGTAA
TTTTACTTTGATCAATGTTTTCAATATTATCTGCACAATTGACTGATTAT
TATTAAATTATTCGTGTCAATGTTTGTTTGTCCATTTTGAATGGTTCTTT
AATGTTGACTGATTTATTTAACTAGGTCAGTAGATTATCAATTTACAAAT
AACAACAAAATTCG

protein sequence of SMED30007795-orf-1

>SMED30007795-orf-1 ID=SMED30007795-orf-1|Name=SMED30007795-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=146bp
MARLTEMELNDALETFALFDTKGDSKIEAKQIGEVVRALGLNPTEAEIKK
CGYNNQDERISFEIFIPIYQSLMKQKVVSDPQEFVEGFKVFDKDGNGMIS
AAELRHLLTAIGERLRESEVDALLAGMENSQGQISYEDFVHHIMN*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR002048	EF_hand_dom
IPR011992	EF-hand-dom_pair
IPR018247	EF_Hand_1_Ca_BS

Vocabulary: **molecular function**
Term	Definition
GO:0005509	calcium ion binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002048	EF-hand domain	SMART	SM00054	efh_1	coord: 11..39 e-value: 19.0 score: 7.5 coord: 83..111 e-value: 1.2E-4 score: 31.5
IPR002048	EF-hand domain	PFAM	PF13499	EF-hand_7	coord: 88..142 e-value: 1.4E-7 score: 31.8
IPR002048	EF-hand domain	PROSITE	PS50222	EF_HAND_2	coord: 79..114 score: 13.872
IPR002048	EF-hand domain	PROSITE	PS50222	EF_HAND_2	coord: 7..42 score: 10.273
IPR002048	EF-hand domain	CDD	cd00051	EFh	coord: 83..144 e-value: 1.62641E-12 score: 56.7873
None	No IPR available	GENE3D	G3DSA:1.10.238.10		coord: 81..145 e-value: 4.6E-20 score: 73.5
None	No IPR available	GENE3D	G3DSA:1.10.238.10		coord: 1..80 e-value: 4.3E-18 score: 67.4
None	No IPR available	PANTHER	PTHR23048	MYOSIN LIGHT CHAIN 1, 3	coord: 9..145
IPR018247	EF-Hand 1, calcium-binding site	PROSITE	PS00018	EF_HAND_1	coord: 92..104
IPR011992	EF-hand domain pair	SUPERFAMILY	SSF47473	EF-hand	coord: 8..144