Ankyrin repeat domain 28b
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30007716 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Ankyrin repeat domain 28b vs. Ensembl Human
Match: ANKRD28 (ankyrin repeat domain 28 [Source:HGNC Symbol;Acc:HGNC:29024]) HSP 1 Score: 516.538 bits (1329), Expect = 4.307e-163 Identity = 349/1064 (32.80%), Postives = 539/1064 (50.66%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD---VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
P+L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH E+VK+LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI +I+N +N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I++ A ++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D ++PLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K+ VH++ G+ L L+++ +E +D + +++S D S D +S +HLAAYHGH + L LVQ + ++ SGRT L LAA++GH V L++ GA D +H AA+ G + L +I + + +N VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECVD LL AK L D RGR +++A+ GH +L L+ A+ + D T LH+A GH C+E+L E K+ + LHCA+ + + E ++ ++N D TP+ A D+V L+ L+ HNA +N D G TP+M+AA+ G + + +L+ + + L D S LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M
Sbjct: 10 PSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDAN----PGIRD----------------KQGYNAVHYSAAYGHR----LCLQLIASETPLDVL---METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLD--LDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASM----------------DANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKI-TDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 984
BLAST of Ankyrin repeat domain 28b vs. Ensembl Human
Match: ANKRD28 (ankyrin repeat domain 28 [Source:HGNC Symbol;Acc:HGNC:29024]) HSP 1 Score: 516.538 bits (1329), Expect = 4.307e-163 Identity = 349/1064 (32.80%), Postives = 539/1064 (50.66%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD---VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
P+L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH E+VK+LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI +I+N +N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I++ A ++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D ++PLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K+ VH++ G+ L L+++ +E +D + +++S D S D +S +HLAAYHGH + L LVQ + ++ SGRT L LAA++GH V L++ GA D +H AA+ G + L +I + + +N VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECVD LL AK L D RGR +++A+ GH +L L+ A+ + D T LH+A GH C+E+L E K+ + LHCA+ + + E ++ ++N D TP+ A D+V L+ L+ HNA +N D G TP+M+AA+ G + + +L+ + + L D S LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M
Sbjct: 10 PSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDAN----PGIRD----------------KQGYNAVHYSAAYGHR----LCLQLIASETPLDVL---METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLD--LDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASM----------------DANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKI-TDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 984
BLAST of Ankyrin repeat domain 28b vs. Ensembl Human
Match: ANKRD52 (ankyrin repeat domain 52 [Source:HGNC Symbol;Acc:HGNC:26614]) HSP 1 Score: 493.041 bits (1268), Expect = 4.652e-154 Identity = 343/1108 (30.96%), Postives = 543/1108 (49.01%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDD-------------DGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAA---MYNKEGDILRLLFDNGANILSPININDH------LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAM--FSSTD--SPANLALKTSLNLSPKK 3315
P L +I D + +R L K ++N+ D +T LH AAY+G+ I +L+ G +VN+KD +TPL +A AS + VL +L++ AD N RD W HV AA+ + C + + P + +N+ D GR+ALHHAV +GH+E V +LL+ S++ DK +P+HWAA G LE+L LL+ A++ +D+ Y LH A+A G I++V L+ GAE+D GN ALH+A + EL+ A + +N N +G T LH+ + N C++LL+ GA+ N S+ GKSPLH AA + ++ +LI+ ++++ D NTPLH+A R+G+E + L+ A+ G M P+H+A F C KLL + L + +++L + D LGR +H A +GG+++CL ++ G D+ D +TPLH A ++ L+ GA ++ D C +HYAA Y + D A P+ + L F+ +N D + ++ VH+A GN + LLLEM +C++ D +S V S +HLAAY+GH E L L + + +D GRTAL LA +G V+ L + GA ++ W LH AA+ G D+L+ +I S + R + D +D + ++PLM+A+ NGH L+ G+ D D GRT+LHR G +C+ LLD +A + DF+GR ++A++ GH +L L+ Q D + D +P+H+A+ GH +C+E+L E S T LHCA+ + D T E +L ++N+ D TP+ A DNV+ L L+ H A++N D G T +M AA+ G + + LL ++D++ LH A + C ++IL + L LIN+ ++ Q P H+AA N L + AL++ GA + + + P ++C N +DC+ + L+ M F D SP + +L + +++ K
Sbjct: 10 PPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNA-----------------------------------GANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVNYQSKEGKSPLHMAAIHGRFTRSQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTYRRAEPHTPSSHD--AEEDEPLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEM-----SFNCLE--------DVESTIPV-SPLHLAAYNGHCEALKTLAETLVN--LDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGE---RADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLL--------QAALSTDPLDAGV--------DYSGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDAKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDL-GLINATNSALQMPLHIAARNGLASVVQALLSHGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKPFPPKDAVSPFSFSLLKNCSIAAAK 1044 HSP 2 Score: 142.51 bits (358), Expect = 1.340e-33 Identity = 200/802 (24.94%), Postives = 322/802 (40.15%), Query Frame = 1
Query: 1045 NLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGAN----------ILSPININDHLSFI-----------ENNIMDNTS------LGKKIV-------------------YPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSL-DEH--------------KRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINE--LKSMWF---------------DQDYLTPLHFAASRGHTNCIEMLYELS----DEMKSTNGFMTFLHCAIDSKCD------ETL-----------------------EC--VLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLI--LHNADI-NYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAA 3102
+LS + PL A +++ L+ K ++N+ D TPLH A G +Q+LL AN + P+H A A +N + LL + +N D L + +H A A + KC E + L ++ D ++ LH AV + +L+ GAS++V D+ +H+AA ++L+LL GA+ +L + + + E N NT+ LG+ V P+H A +S N L LE++ N + + +YQSK+ S +H+AA HG L+Q S+ + D+ G T LH+AA GH + + L++ GA TA + LH A G D +++ S +L S+V SL +EH R+ L A G+ L+ +GAD+ +D +GRT LH A ANG +C L+ A + D +G + + AA++ Y + H + D + E K +F D+ T +H+AA+ G+ +E+L E+S ++++ST A + C+ ETL EC VL + K WTP+ A + ++L LI ADI + D G TP+M+A G + C++LLLE + A D + LH + + C +L+ + D +TP HLA+
Sbjct: 2 GILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAH---SADVNARDK--LWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHL-EVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNG---ALCLELLVN-----------NGADVNYQSKEGK-SPLHMAAIHGRFTRSQILIQNGSE--IDCADKFGNTPLHVAARYGHELLISTLMTNGAD-TARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQL---YSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASD---------TYRRAEPHTPSSHDAEEDEPLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADA-ADLRGRTALHRGAVTGCEDCLAALLDH----DAFVLCRDFKGRTPIHLAS 762
BLAST of Ankyrin repeat domain 28b vs. Ensembl Human
Match: ANKRD44 (ankyrin repeat domain 44 [Source:HGNC Symbol;Acc:HGNC:25259]) HSP 1 Score: 421.779 bits (1083), Expect = 9.555e-128 Identity = 324/1115 (29.06%), Postives = 514/1115 (46.10%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIAD---------------------------------ILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDN-VTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAM--YNKEGDILRLLFDNGANILSPININDH-----LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD--VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLAL 3285
P L +I D + +R ++ DVN D+ +T LH+AA++G++ I + +LIK+ DVN++D N TPL HV AA+ +V C ++I+P + +N++D GRTALHHA NGH+E+V +LL +I+A DK R +HWAA G L+++ LL+++ A + +DK YT LH A++ G I++V L+ G E+D + GN ALH+A N +V ELI + +N N G T LH + + C++LL+ GA+ N+ S++GKSPLH A + ++ LI+ +++ D NTPLH+A R+G+E + L+ A+ G M P+H+A + C KLL + + T D GR +H A AGG+++C++ + G D H +D +TPLH A +F L+ GA+++ D++ A+HYAA ++ IL DN + + + L F+ N + + K+ +H+A G+ + LLLE + + ++ D S +HLAAY+GH + L L+Q + +D GRTAL LAA++GH V+ L++ GA D LH + G L L +++ + VD D ++PLM+AV GH L+ A+VD D G T+LHR GH ECV +LL+ I D RGR + AA+ GH L +L+ + ++E + D TPLH+A G+ NCIE+L E K T LHCAI + +L ++ +++ D TP+ A D+V L+ L+ H+A +N D +G T +M+AA+ G +++L+ + DK LH A + C ++IL+K+ + LIN +N QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M + S +A+
Sbjct: 10 PPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPL---------------------------------HVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELID-----------------------------------YGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDT------PDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNKTILGNAHDNSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLE----------------RTNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQSLVD--LDIRDEKGRTALDLAAFKGHTECVEALINQGASIFVKDNVTKRTPLHASVINGHTLCLR---LLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQ-----------------MALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLHAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQ-DESLINEKNNALQTPLHVAARNGLKVVVEELLAKGACVLAVDENGHTPALACAPNKDVADCLALILATMMPFSPSSTMMAV 1011 HSP 2 Score: 155.221 bits (391), Expect = 1.763e-37 Identity = 207/827 (25.03%), Postives = 347/827 (41.96%), Query Frame = 1
Query: 1066 KSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGML--PIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANIL-------SP---------ININDHL-----SFIENNIMDNTSL------GKKIVY-------------------PVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAF-YMAASAGHKNLLMKLINYVANKYHQGDFIEKSHD------------IFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSD---EMKSTNGFMTFLHCAIDSKCDETLECVLK-IANNDLINTPDKYSWTPIFYAVHDDNVNAL------------------------------EKLILHNAD----INYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFG---ADLYLKNFKSQLPIVSCGRNSKASDCIEICL 3240
+ PL A ++ +LI DVN D + TPLH+A G + +++L+ + A V +D M P+H A A ++ + L+ + +N D + + +H A A ++KC E II L ++ D +T LH A + + +L+ GA+I+ D+ A+H+AA Y D++ LL ++GA + +P IN+ HL E N+ NT+L G+ V P+HFA S + L LE++ N + + + QSKD S +H+ A HG L+Q + + D+ G T LH+AA GH + + L++ GA TA + LH AA D ++ LS E +D+ D+ R+ L A G+ + L +GAD KD GRT LH A AN H C++ L+ A + D GR A Y AAS +N + + N + + +E++ + + N+ D++ +H+AA+ GH C+E+L E ++ E + + LH A + + LE +L+ + + D+ + + + + H + V AL +L+L AD ++ +D G TP+M+A G + ++LLLE + VD LH + + C ++LE+ + I D+ +TP H AA +L+ L+ D K+ + P+ N +CIE+ L
Sbjct: 9 QPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLI--LSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKH---SADVNARDKN--WQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAA-YMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHG---ALCLELLVN-----------NGADVNIQSKDGK-SPLHMTAVHGRFTRSQTLIQ--NGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGAD-TAKCGIHSMFPLHLAALNAHSDCCRKL-LSSGFE-----IDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNKTI-----LGNAHDNSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLE-KEANVDTVDILGCTALHRGIMTGHEECVQMLLEQ----EVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGN-ENCIEVLL 792
BLAST of Ankyrin repeat domain 28b vs. Ensembl Human
Match: ANKRD44 (ankyrin repeat domain 44 [Source:HGNC Symbol;Acc:HGNC:25259]) HSP 1 Score: 404.445 bits (1038), Expect = 6.400e-122 Identity = 314/1070 (29.35%), Postives = 494/1070 (46.17%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIAD---------------------------------ILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDN-VTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAM--YNKEGDILRLLFDNGANILSPININDH-----LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD--VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGA 3150
P L +I D + +R ++ DVN D+ +T LH+AA++G++ I + +LIK+ DVN++D N TPL HV AA+ +V C ++I+P + +N++D GRTALHHA NGH+E+V +LL +I+A DK R +HWAA G L+++ LL+++ A + +DK YT LH A++ G I++V L+ G E+D + GN ALH+A N +V ELI + +N N G T LH + + C++LL+ GA+ N+ S++GKSPLH A + ++ LI+ +++ D NTPLH+A R+G+E + L+ A+ G M P+H+A + C KLL + + T D GR +H A AGG+++C++ + G D H +D +TPLH A +F L+ GA+++ D++ A+HYAA ++ IL DN + + + L F+ N + + K+ +H+A G+ + LLLE + + ++ D S +HLAAY+GH + L L+Q + +D GRTAL LAA++GH V+ L++ GA D LH + G L L +++ + VD D ++PLM+AV GH L+ A+VD D G T+LHR GH ECV +LL+ I D RGR + AA+ GH L +L+ + ++E + D TPLH+A G+ NCIE+L E K T LHCAI + +L ++ +++ D TP+ A D+V L+ L+ H+A +N D +G T +M+AA+ G +++L+ + DK LH A + C ++IL+K+ + LIN +N QTP H+AA N L + + L+ GA
Sbjct: 10 PPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPL---------------------------------HVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELID-----------------------------------YGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDT------PDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNKTILGNAHDNSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLE----------------RTNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQSLVD--LDIRDEKGRTALDLAAFKGHTECVEALINQGASIFVKDNVTKRTPLHASVINGHTLCLR---LLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQ-----------------MALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLHAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQ-DESLINEKNNALQTPLHVAARNGLKVVVEELLAKGA 966 HSP 2 Score: 218.779 bits (556), Expect = 1.459e-57 Identity = 263/976 (26.95%), Postives = 409/976 (41.91%), Query Frame = 1
Query: 76 LFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILL---------------------------------DNNTSISASDKNGVRPIHWAAARGXXXX-XXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSS------HLFLEHLKS-NSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIA------------------------CRFGYEKFVQMLLEY----KANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVL--SLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLL--SCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLEN---RKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLI--MNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNC-IEMLYELSDEM---KSTNGFMTFLHCAIDSKCDETLE-------CVLKIANN 2736
L ++ + ++ + + DVN +D QT LH+AA A+++I VN D G T L A + ++ +L++ GA+ N D K RA H A +D + L++ H + D G T LH A +NG I VVK LL D +++ + NG P+H+AAA + L LL++N A++NI+ KD + LH+ + G LI+ G E+DCV GN LH+A+ H ++ LI + + +F HL + N+H D ++ + F +++ + G T LH + N +C+ LL + GA+ + + G++PLH+AA+ L+ A+VN DD T LH A R EK + LE+ AN + ++G IH A A+ + C+ LL+ + D G ++ +H A G + LE +++ D+ D +T L LA + LI GASI V+D T +A++ N LRLL + N +++ D K P+ AV G+ D + LLLE EA +D + D+L + +H GH E + L++ + + +D GRT LH AA +GHA + LL + + + + LH+A G NE + V LE RK + + +PL A+ N H A L+ ++ + V +D GRT LH A HVEC+ LLL +A + D G+ A MAA G + L+N Q D K D+D TPLH A S+GH C + +L ++ DE + N T LH A + +E CVL + N
Sbjct: 78 LHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFE---------IDTPDKFGRTCLHAAAAGGNV-ECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNKTILGNAHDNSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEES---DSGATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNP-EAVDVKD----------------AKGQTPLMLAVAYGHIDAVSLLLE---KEANVDTV---------------DILGCTALHRGIMTGHEECVQMLLE--QEVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNG-----NENCIEVLLEQKCFRKFIGNPF-----TPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLHAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSA-----QADLTVK--------------DKDLNTPLHLACSKGHEKCALLILDKIQDESLINEKNNALQTPLHVAARNGLKVVVEELLAKGACVLAVDEN 974 HSP 3 Score: 142.51 bits (358), Expect = 1.452e-33 Identity = 139/488 (28.48%), Postives = 215/488 (44.06%), Query Frame = 1
Query: 1903 AAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYW-NALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFM-TFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPI-FYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGYVINLKEAELEGS 3357
A + G E + L I V+T D RT LH+AA+ G A ++ L+ GA+ A KD W LH A + S +A+ +I + V++ D++ ++PL +A N + AE +I + V++ D GRT+LH A NGHVE V+LLL A I FD + R A + AA GH +++ LIN+ A + D+ TPLH AAS G N ++ L L E+ N + T LH A + D + ++ N +N P+ +TP+ F A LE L+ + AD+N Q +G +P+ + A G + +Q ++ G+ I+ +D + TP H+AA L +N LIT GAD S P+ N+ SDC L++ F D+P +T L+ + G V +K + G+
Sbjct: 15 AIFSGDPEEIRML--IHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNA--KDNMWLTPLHRAVASRSEEAVQVLI------KHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGA--------------------EVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN--VNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFT------------------RSQTLIQNGGE--------------------IDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAH-SDCCRKLLSSGF-EIDTPDKFG-RTCLHAAAAGGNVECIKLLQSSGA 429 HSP 4 Score: 134.42 bits (337), Expect = 4.183e-31 Identity = 180/719 (25.03%), Postives = 295/719 (41.03%), Query Frame = 1
Query: 1348 INNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTA-EKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGF-MTFLHCAIDSKCDETLECV--LKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAA-----------------------------KEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKL-------------------------PCLKKLINSL------DNNQQTPAHLAAFNSLPLFLNALITFGADLYLK-NFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSP 3309
+N LD + R +H A G + +E +I G ++ +DN+ TPLH AV + ++LIK A ++ D+ +H AA NK ++ +LS +N++D G + +H A ++G+ + + LLL KG ++ N + KD +H AAY GH +++ L+ ++ V+ +D+ G T LH AA G VK LL+ G + ++ Y ALH A G +NE+I + + V+ + + +PL A + H E L+ NGADV+++ G++ LH +G L+ +I+ D G ++AA GH+ L+ LI A+ G H +F PLH AA H++C L E+ + + F T LH A +EC+ L+ + D + DK TP+ YA + + + +E L+ A++N D G T + AA KE TL CL LL+ ++ DK N +HYA C ++LE+ L+ L+ SL D +T LAAF + ALI GA +++K N + P+ + N +CL + D+P + +K + +P
Sbjct: 34 VNTLDSEK--RTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAA-NKAVKCAEVIIP----LLSSVNVSDR--------------GGRTA--LHHAALNGHVEMVNLLL-----------AKG---ANINAFDKKDR--RALHWAAYMGHLDVVALLINHGAE--VTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINV-YGNTALHIACYNGQDAVVNELI------DYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCG-----IHSMF---------------PLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGG---NVECIKLLQSSGADF-HKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNKTILGNAHDNSEELERARELKEKEATL-CLEFLLQ-NDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINQGASIFVKDNVTKRTPLHASVINGHT-----LCLRLLLEIADNPEAVDVKDAKGQTP 673
BLAST of Ankyrin repeat domain 28b vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 204.142 bits (518), Expect = 1.724e-52 Identity = 212/807 (26.27%), Postives = 353/807 (43.74%), Query Frame = 1
Query: 139 DVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVR--PIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPINI------NDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEM---MPNEAKMDCIKGHVDSSQNDYQ--------------SKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKL 2463
D+N +A +LHLA+ G+S + LIK V++ G T L A + ++T+L+ +GA+ N + ++ A N + +K +L H ++ DG T L A+ GH VV +LL+N++ K VR +H AA + D LLL N+ N ++ K +T LHIA+ GH ++ L+EKGA ++ ++ H+ + ++N L+ +I++SR LT LH ++ + Q VDLL+ GA + ++NG +PLH AA + + A L+ +A V+ TPLH+A G+ + ++LL+ A+ +G P+H+A + LL + I + GL +H A G++ + +++ G + E +TPLHLA + N + R+LI+ GA +D + +H A+ DI+ LL GAN SP++I + + ++ D T L KK P+H A GN + + LLLE + E K HV + N+ + + + + +H+AA EI + L+Q K + + R+G T LHL+A +GH L+ G+ A + A+H A + V ++ L N + ++S +PL +A G + L+ NGADV K T LH+A GH CV LL+ A G+ +A G+ +++ L
Sbjct: 58 DINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDS------KGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHN----------------------ISPLHVATKWGRTNMANLLLSR-------------GAIIDSRTKDLLTPLHCAARSGH-DQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLL---KYRAAIEATTESGL--TPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNT-DIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQF--KADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGA-KANNGLTAMHLCAQEDHVP------VAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 2 Score: 191.045 bits (484), Expect = 2.012e-48 Identity = 213/831 (25.63%), Postives = 332/831 (39.95%), Query Frame = 1
Query: 55 NTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNC--------------------------RDNKWN---RAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIK------------------ALNSSHLFLEHL----KSNSHQDLIEEIKDNHFVLIKERLESI---------LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDV-LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLL 2364
N N + +L + E S+ +R + + V+ TALH+A+ G S I IL++ G +VN + VNG TPL+ A N V+ L+ GA+ D+K A H+ A + L+L + ++T G T LH A GH V ++LL+ +++ ++ + P+H A G + NLLL A ++ R KD T LH A+ GH +V L+ +GA + T G LH+A+ +H + L+ A + H+ + L ++ + + H K R++ + + + GLT LH+ + M A V LL GANP++ + G++PLH AA NQ +LI+ A V+ Q TPLHIA R G V +LL+ AN+ D P+H+A LLD+ KT L G TPLHLA K N + R+L++ G +D+E + +H AA YN + + LL +NGA+ + K P+H A + LL+ + D +K + +HL+A GH EI L++ S V + +G TA+HL A + H + L + GA+ + Y LH A G ++ + ++ EN V +PL A Q GH L+ NGA + + G+T L A G+V V+ L
Sbjct: 63 NANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFM-GAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTL---LTKKGF-----------------------------------TPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNND-KVAMLLLENGASA--------------------KAAAKNGYTPLHIAAKKNQMEIASTLLQF-----------------KADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSD--VGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGY-TPLHVACHFGQLNMVKFLV-----ENGAD-VGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 3 Score: 181.03 bits (458), Expect = 2.050e-45 Identity = 192/761 (25.23%), Postives = 336/761 (44.15%), Query Frame = 1
Query: 439 INITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCV-DLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGAN-------------ILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNE---AKMDCIKGHVDSSQN---------DYQSKDDVLSL-----IHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYE 2628
IN ++++G +LH A GH EVV+ L+ + A+ + G +H A+ G I+ +L++N AN+N++ + +T L++A+ H ++V L++ GA T G L +A H +V L++ + + L L + +D D + + E + + G T LHI + H+ V LLL GAN N + + SPLH A + A LL+ A ++ + TPLH A R G+++ V +L+ A ++G+ P+H+A + LL + + ++++ D L +H A G ++ + ++ D + TPLH+A K N + +L+K A+I+ E +H AA ++ LL GAN + + N D + + N + +++ P+H A GN D +ILLL+ N + + H+ + + D+ + +L+ +HLA+ +G+ E++ L++ V + ++ T LH+AA+ + LL GA A K+ Y LH AA + N+M ++ L K+ ++ +PL ++ Q GH + LI NG+DV K G T++H HV +L + A+I G ++A G N++ L+ + D EK+ + TPLH AA +GH NC+ L E
Sbjct: 59 INTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKD------DTTAATLLLQNEHNPDVTSKSGFTPLHIAAHY--GHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYH---RAPVDDVTVDYL--TPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLL-QQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLE--RGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGY-TPLHIAAKK------NQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVE------NGADVGEKTRASY--------------TPLHQAAQQGHNNCVRYLLE 776 HSP 4 Score: 137.887 bits (346), Expect = 3.344e-32 Identity = 170/718 (23.68%), Postives = 296/718 (41.23%), Query Frame = 1
Query: 1036 ANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGA---------NILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKS-TNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGAD 3153
A P G + AA L++ + L++A D+N + + LH+A + G+ + V+ L++ +A A G +H+A+ +AG SL + ++ G +++ + TPL++A + N+ + + L+K GA ++ ED +T +A+ A+ ++ +L +N + +I + + + + N + K P+H A G+ + LLLE N +YQ++ ++ S +H+A G + + N L+ I+ ++ + T LH AA GH V L+ GA +A K+ LH AA VDA ++ ++ VD + +PL +A GH R A+ L+ AD + + G T LH A ++ V+LLL A IE G ++AA G N+++ L+ AN +++++ + TPLH AA T+ + +L ++ + T LH A + + +L+ N T D YS P+ A + L+ HNAD G TP+ +A+K G L + LLLE T + K+ LH A +D +++LE K + N TP H+AA + + L+ F AD
Sbjct: 24 AAPEPGRAEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIAS-------------------------------------LAGQSL-IVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAV---ALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANV---------------NYQARHNI-SPLHVATKWGRTNMANLLLS--RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGL-APLHMAAQGDHVDAARTLLY------HRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANP----------------DVETVRGE----TPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYS--PLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAK----AAAKNGYTPLHIAAKKNQMEIASTLLQFKAD 648
BLAST of Ankyrin repeat domain 28b vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 204.142 bits (518), Expect = 1.724e-52 Identity = 212/807 (26.27%), Postives = 353/807 (43.74%), Query Frame = 1
Query: 139 DVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVR--PIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPINI------NDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEM---MPNEAKMDCIKGHVDSSQNDYQ--------------SKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKL 2463
D+N +A +LHLA+ G+S + LIK V++ G T L A + ++T+L+ +GA+ N + ++ A N + +K +L H ++ DG T L A+ GH VV +LL+N++ K VR +H AA + D LLL N+ N ++ K +T LHIA+ GH ++ L+EKGA ++ ++ H+ + ++N L+ +I++SR LT LH ++ + Q VDLL+ GA + ++NG +PLH AA + + A L+ +A V+ TPLH+A G+ + ++LL+ A+ +G P+H+A + LL + I + GL +H A G++ + +++ G + E +TPLHLA + N + R+LI+ GA +D + +H A+ DI+ LL GAN SP++I + + ++ D T L KK P+H A GN + + LLLE + E K HV + N+ + + + + +H+AA EI + L+Q K + + R+G T LHL+A +GH L+ G+ A + A+H A + V ++ L N + ++S +PL +A G + L+ NGADV K T LH+A GH CV LL+ A G+ +A G+ +++ L
Sbjct: 58 DINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDS------KGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHN----------------------ISPLHVATKWGRTNMANLLLSR-------------GAIIDSRTKDLLTPLHCAARSGH-DQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLL---KYRAAIEATTESGL--TPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNT-DIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQF--KADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGA-KANNGLTAMHLCAQEDHVP------VAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 2 Score: 191.045 bits (484), Expect = 2.012e-48 Identity = 213/831 (25.63%), Postives = 332/831 (39.95%), Query Frame = 1
Query: 55 NTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNC--------------------------RDNKWN---RAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIK------------------ALNSSHLFLEHL----KSNSHQDLIEEIKDNHFVLIKERLESI---------LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDV-LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLL 2364
N N + +L + E S+ +R + + V+ TALH+A+ G S I IL++ G +VN + VNG TPL+ A N V+ L+ GA+ D+K A H+ A + L+L + ++T G T LH A GH V ++LL+ +++ ++ + P+H A G + NLLL A ++ R KD T LH A+ GH +V L+ +GA + T G LH+A+ +H + L+ A + H+ + L ++ + + H K R++ + + + GLT LH+ + M A V LL GANP++ + G++PLH AA NQ +LI+ A V+ Q TPLHIA R G V +LL+ AN+ D P+H+A LLD+ KT L G TPLHLA K N + R+L++ G +D+E + +H AA YN + + LL +NGA+ + K P+H A + LL+ + D +K + +HL+A GH EI L++ S V + +G TA+HL A + H + L + GA+ + Y LH A G ++ + ++ EN V +PL A Q GH L+ NGA + + G+T L A G+V V+ L
Sbjct: 63 NANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFM-GAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTL---LTKKGF-----------------------------------TPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNND-KVAMLLLENGASA--------------------KAAAKNGYTPLHIAAKKNQMEIASTLLQF-----------------KADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSD--VGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGY-TPLHVACHFGQLNMVKFLV-----ENGAD-VGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 3 Score: 181.03 bits (458), Expect = 2.050e-45 Identity = 192/761 (25.23%), Postives = 336/761 (44.15%), Query Frame = 1
Query: 439 INITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCV-DLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGAN-------------ILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNE---AKMDCIKGHVDSSQN---------DYQSKDDVLSL-----IHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYE 2628
IN ++++G +LH A GH EVV+ L+ + A+ + G +H A+ G I+ +L++N AN+N++ + +T L++A+ H ++V L++ GA T G L +A H +V L++ + + L L + +D D + + E + + G T LHI + H+ V LLL GAN N + + SPLH A + A LL+ A ++ + TPLH A R G+++ V +L+ A ++G+ P+H+A + LL + + ++++ D L +H A G ++ + ++ D + TPLH+A K N + +L+K A+I+ E +H AA ++ LL GAN + + N D + + N + +++ P+H A GN D +ILLL+ N + + H+ + + D+ + +L+ +HLA+ +G+ E++ L++ V + ++ T LH+AA+ + LL GA A K+ Y LH AA + N+M ++ L K+ ++ +PL ++ Q GH + LI NG+DV K G T++H HV +L + A+I G ++A G N++ L+ + D EK+ + TPLH AA +GH NC+ L E
Sbjct: 59 INTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKD------DTTAATLLLQNEHNPDVTSKSGFTPLHIAAHY--GHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYH---RAPVDDVTVDYL--TPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLL-QQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLE--RGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGY-TPLHIAAKK------NQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVE------NGADVGEKTRASY--------------TPLHQAAQQGHNNCVRYLLE 776 HSP 4 Score: 137.887 bits (346), Expect = 3.344e-32 Identity = 170/718 (23.68%), Postives = 296/718 (41.23%), Query Frame = 1
Query: 1036 ANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGA---------NILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKS-TNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGAD 3153
A P G + AA L++ + L++A D+N + + LH+A + G+ + V+ L++ +A A G +H+A+ +AG SL + ++ G +++ + TPL++A + N+ + + L+K GA ++ ED +T +A+ A+ ++ +L +N + +I + + + + N + K P+H A G+ + LLLE N +YQ++ ++ S +H+A G + + N L+ I+ ++ + T LH AA GH V L+ GA +A K+ LH AA VDA ++ ++ VD + +PL +A GH R A+ L+ AD + + G T LH A ++ V+LLL A IE G ++AA G N+++ L+ AN +++++ + TPLH AA T+ + +L ++ + T LH A + + +L+ N T D YS P+ A + L+ HNAD G TP+ +A+K G L + LLLE T + K+ LH A +D +++LE K + N TP H+AA + + L+ F AD
Sbjct: 24 AAPEPGRAEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIAS-------------------------------------LAGQSL-IVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAV---ALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANV---------------NYQARHNI-SPLHVATKWGRTNMANLLLS--RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGL-APLHMAAQGDHVDAARTLLY------HRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANP----------------DVETVRGE----TPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYS--PLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAK----AAAKNGYTPLHIAAKKNQMEIASTLLQFKAD 648
BLAST of Ankyrin repeat domain 28b vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 189.504 bits (480), Expect = 3.578e-48 Identity = 211/807 (26.15%), Postives = 351/807 (43.49%), Query Frame = 1
Query: 139 DVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVR--PIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPINI------NDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPN---EAKMDCIKGHVDSSQNDYQ--------------SKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKL 2463
D+N +A +LHLA+ G+S + LIK V++ G T L A + ++T+L+ +GA+ N + ++ A N + +K +L H ++ DG T L A+ GH VV +LL+N++ K VR +H AA + D LLL N+ N ++ K +T LHIA+ GH ++ L+EKGA ++ ++ H+ + ++N L+ +I++SR LT LH ++ + Q VDLL+ GA + ++NG +PLH AA + + A L+ +A V+ TPLH+A G+ + ++LL+ A+ +G P+H+A + LL + I + GL +H A G++ + +++ G + E +TPLHLA + N + R+LI+ GA +D + +H A+ DI+ LL GAN SP++I + + ++ D T L KK P+H A GN + + LLLE E K HV + N+ + + + + +H+AA EI + L+Q K + + R+G T LHL+A +GH L+ G+ + A+H A + V ++ L N + ++S +PL +A G + L+ NGADV K T LH+A GH CV LL+ A G+ +A G+ +++ L
Sbjct: 58 DINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDS------KGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHN----------------------ISPLHVATKWGRTNMANLLLSR-------------GAIIDSRTKDLLTPLHCAARSGH-DQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLK---YRAAIEATTESGL--TPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNT-DIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQF--KADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSD-VGAKANNGLTAMHLCAQEDHVP------VAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 2 Score: 172.94 bits (437), Expect = 4.647e-43 Identity = 216/840 (25.71%), Postives = 335/840 (39.88%), Query Frame = 1
Query: 55 NTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCR--------------------------DNKWN---RAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELI----KALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAY---------------------------------GANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDV-LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMI---LSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLL 2364
N N + +L + E S+ +R + + V+ TALH+A+ G S I IL++ G +VN + VNG TPL+ A N V+ L+ GA+ D+K A H+ A + L+L + ++T G T LH A GH V ++LL+ +++ ++ + P+H A G + NLLL A ++ R KD T LH A+ GH +V L+ +GA + T G LH+A+ +H + L+ + + +L L +H + K L+ +R + NSR G T LHI + N + V+LLL Y GANP++ + G++PLH AA NQ +LI+ A V+ Q TPLHIA R G V +LL+ AN+ D P+H+A LLD+ KT L G TPLHLA K N + R+L++ G +D+E + +H AA YN + + LL +NGA+ + K P+H A + LL+ + D +K + +HL+A GH EI L++ S V + +G TA+HL A + H + L + GA+ + + + LH A G ++ + ++ V + R S +PL A Q GH L+ NGA + + G+T L A G+V V+ L
Sbjct: 63 NANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAK-----LLLDR-SADPNSRALNGFTPLHIACK-KNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTL---LTKKGF-----------------------------------TPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNND-KVAMLLLENGASA--------------------KAAAKNGYTPLHIAAKKNQMEIASTLLQF-----------------KADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSD--VGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINS-KTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASY---------TPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 3 Score: 162.155 bits (409), Expect = 8.118e-40 Identity = 198/776 (25.52%), Postives = 337/776 (43.43%), Query Frame = 1
Query: 439 INITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCV-DLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLL------DNVTLK-----------THIN------NLDDDGLGRNL-----VHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNE---AKMDCIKGHVDSSQN---------DYQSKDDVL-----SLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYE 2628
IN ++++G +LH A GH EVV+ L+ + A+ + G +H A+ G I+ +L++N AN+N++ + +T L++A+ H ++V L++ GA T G L +A H +V L++ + + L L + +D D + + E + + G T LHI + H+ V LLL GAN N + + SPLH A + A LL+ A ++ + TPLH A R G+++ V +L+ A ++G+ P+H+A + LL D+VT+ H+ + D R L +H A +K +E +++ I TPLH+A + I L++ GA+ DVE +H AA N+ D++R+L NGA + + +++ P+H A GN D +ILLL+ N + + H+ + + D+ + +L + +HLA+ +G+ E++ L++ + V + ++ T LH+AA+ + LL GA A K+ Y LH AA + N+M ++ L K+ ++ +PL ++ Q GH + LI NG+DV K G T++H HV +L + A+I G ++A G N++ L+ A D EK+ + TPLH AA +GH NC+ L E
Sbjct: 59 INTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKD------DTTAATLLLQNEHNPDVTSKSGFTPLHIAAHY--GHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQT-DVVRVLIRNGAKV--------------------DAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTP--VDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGY-TPLHIAAKK------NQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGA------DVGEKTRASY--------------TPLHQAAQQGHNNCVRYLLE 776 HSP 4 Score: 127.102 bits (318), Expect = 4.305e-29 Identity = 175/730 (23.97%), Postives = 303/730 (41.51%), Query Frame = 1
Query: 1036 ANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDN---GANILSPINI------NDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKS-TNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI 3189
A P G + AA L++ + L++A D+N + + LH+A + G+ + V+ L++ +A A G +H+A+ +AG SL + ++ G +++ + TPL++A + N+ + + L+K GA ++ ED +T +A+ A+ ++ +L +N G L ++I + + N + K P+H A G+ + LLLE KG + +YQ++ ++ S +H+A G + + N L+ + I+ ++ + T LH AA GH V L+ GA +A K+ LH AA VDA ++ ++ VD + +PL +A GH R A+ L+ AD + + G T LH A ++ V+LLL A IE G ++AA G N+++ L+ AN +++++ + TPLH AA T+ + +L ++ + T LH A + + +L+ N T D YS P+ A + L+ HNAD G TP+ +A+K G L + LLLE T + K+ LH A +D +++LE K + N TP H+AA + + L+ F AD K+ P+
Sbjct: 24 AAPEPGRAEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIAS-------------------------------------LAGQSL-IVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAV---ALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLE-----------KG----ANVNYQARHNI-SPLHVATKWGRTNMANLLLSRGA--IIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLA-PLHMAAQGDHVDAARTLLY------HRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANP----------------DVETVRGE----TPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYS--PLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAK----AAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPL 660
BLAST of Ankyrin repeat domain 28b vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 189.504 bits (480), Expect = 3.578e-48 Identity = 211/807 (26.15%), Postives = 351/807 (43.49%), Query Frame = 1
Query: 139 DVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVR--PIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPINI------NDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPN---EAKMDCIKGHVDSSQNDYQ--------------SKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKL 2463
D+N +A +LHLA+ G+S + LIK V++ G T L A + ++T+L+ +GA+ N + ++ A N + +K +L H ++ DG T L A+ GH VV +LL+N++ K VR +H AA + D LLL N+ N ++ K +T LHIA+ GH ++ L+EKGA ++ ++ H+ + ++N L+ +I++SR LT LH ++ + Q VDLL+ GA + ++NG +PLH AA + + A L+ +A V+ TPLH+A G+ + ++LL+ A+ +G P+H+A + LL + I + GL +H A G++ + +++ G + E +TPLHLA + N + R+LI+ GA +D + +H A+ DI+ LL GAN SP++I + + ++ D T L KK P+H A GN + + LLLE E K HV + N+ + + + + +H+AA EI + L+Q K + + R+G T LHL+A +GH L+ G+ + A+H A + V ++ L N + ++S +PL +A G + L+ NGADV K T LH+A GH CV LL+ A G+ +A G+ +++ L
Sbjct: 58 DINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDS------KGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHN----------------------ISPLHVATKWGRTNMANLLLSR-------------GAIIDSRTKDLLTPLHCAARSGH-DQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLK---YRAAIEATTESGL--TPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNT-DIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQF--KADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSD-VGAKANNGLTAMHLCAQEDHVP------VAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 2 Score: 172.94 bits (437), Expect = 4.647e-43 Identity = 216/840 (25.71%), Postives = 335/840 (39.88%), Query Frame = 1
Query: 55 NTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCR--------------------------DNKWN---RAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELI----KALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAY---------------------------------GANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDV-LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMI---LSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLL 2364
N N + +L + E S+ +R + + V+ TALH+A+ G S I IL++ G +VN + VNG TPL+ A N V+ L+ GA+ D+K A H+ A + L+L + ++T G T LH A GH V ++LL+ +++ ++ + P+H A G + NLLL A ++ R KD T LH A+ GH +V L+ +GA + T G LH+A+ +H + L+ + + +L L +H + K L+ +R + NSR G T LHI + N + V+LLL Y GANP++ + G++PLH AA NQ +LI+ A V+ Q TPLHIA R G V +LL+ AN+ D P+H+A LLD+ KT L G TPLHLA K N + R+L++ G +D+E + +H AA YN + + LL +NGA+ + K P+H A + LL+ + D +K + +HL+A GH EI L++ S V + +G TA+HL A + H + L + GA+ + + + LH A G ++ + ++ V + R S +PL A Q GH L+ NGA + + G+T L A G+V V+ L
Sbjct: 63 NANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAK-----LLLDR-SADPNSRALNGFTPLHIACK-KNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTL---LTKKGF-----------------------------------TPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNND-KVAMLLLENGASA--------------------KAAAKNGYTPLHIAAKKNQMEIASTLLQF-----------------KADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSD--VGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINS-KTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASY---------TPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 3 Score: 162.155 bits (409), Expect = 8.118e-40 Identity = 198/776 (25.52%), Postives = 337/776 (43.43%), Query Frame = 1
Query: 439 INITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCV-DLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLL------DNVTLK-----------THIN------NLDDDGLGRNL-----VHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNE---AKMDCIKGHVDSSQN---------DYQSKDDVL-----SLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYE 2628
IN ++++G +LH A GH EVV+ L+ + A+ + G +H A+ G I+ +L++N AN+N++ + +T L++A+ H ++V L++ GA T G L +A H +V L++ + + L L + +D D + + E + + G T LHI + H+ V LLL GAN N + + SPLH A + A LL+ A ++ + TPLH A R G+++ V +L+ A ++G+ P+H+A + LL D+VT+ H+ + D R L +H A +K +E +++ I TPLH+A + I L++ GA+ DVE +H AA N+ D++R+L NGA + + +++ P+H A GN D +ILLL+ N + + H+ + + D+ + +L + +HLA+ +G+ E++ L++ + V + ++ T LH+AA+ + LL GA A K+ Y LH AA + N+M ++ L K+ ++ +PL ++ Q GH + LI NG+DV K G T++H HV +L + A+I G ++A G N++ L+ A D EK+ + TPLH AA +GH NC+ L E
Sbjct: 59 INTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKD------DTTAATLLLQNEHNPDVTSKSGFTPLHIAAHY--GHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQT-DVVRVLIRNGAKV--------------------DAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTP--VDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGY-TPLHIAAKK------NQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGA------DVGEKTRASY--------------TPLHQAAQQGHNNCVRYLLE 776 HSP 4 Score: 127.102 bits (318), Expect = 4.305e-29 Identity = 175/730 (23.97%), Postives = 303/730 (41.51%), Query Frame = 1
Query: 1036 ANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDN---GANILSPINI------NDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKS-TNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI 3189
A P G + AA L++ + L++A D+N + + LH+A + G+ + V+ L++ +A A G +H+A+ +AG SL + ++ G +++ + TPL++A + N+ + + L+K GA ++ ED +T +A+ A+ ++ +L +N G L ++I + + N + K P+H A G+ + LLLE KG + +YQ++ ++ S +H+A G + + N L+ + I+ ++ + T LH AA GH V L+ GA +A K+ LH AA VDA ++ ++ VD + +PL +A GH R A+ L+ AD + + G T LH A ++ V+LLL A IE G ++AA G N+++ L+ AN +++++ + TPLH AA T+ + +L ++ + T LH A + + +L+ N T D YS P+ A + L+ HNAD G TP+ +A+K G L + LLLE T + K+ LH A +D +++LE K + N TP H+AA + + L+ F AD K+ P+
Sbjct: 24 AAPEPGRAEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIAS-------------------------------------LAGQSL-IVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAV---ALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLE-----------KG----ANVNYQARHNI-SPLHVATKWGRTNMANLLLSRGA--IIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLA-PLHMAAQGDHVDAARTLLY------HRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANP----------------DVETVRGE----TPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYS--PLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAK----AAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPL 660
BLAST of Ankyrin repeat domain 28b vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 189.119 bits (479), Expect = 4.483e-48 Identity = 211/807 (26.15%), Postives = 351/807 (43.49%), Query Frame = 1
Query: 139 DVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVR--PIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPINI------NDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPN---EAKMDCIKGHVDSSQNDYQ--------------SKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKL 2463
D+N +A +LHLA+ G+S + LIK V++ G T L A + ++T+L+ +GA+ N + ++ A N + +K +L H ++ DG T L A+ GH VV +LL+N++ K VR +H AA + D LLL N+ N ++ K +T LHIA+ GH ++ L+EKGA ++ ++ H+ + ++N L+ +I++SR LT LH ++ + Q VDLL+ GA + ++NG +PLH AA + + A L+ +A V+ TPLH+A G+ + ++LL+ A+ +G P+H+A + LL + I + GL +H A G++ + +++ G + E +TPLHLA + N + R+LI+ GA +D + +H A+ DI+ LL GAN SP++I + + ++ D T L KK P+H A GN + + LLLE E K HV + N+ + + + + +H+AA EI + L+Q K + + R+G T LHL+A +GH L+ G+ + A+H A + V ++ L N + ++S +PL +A G + L+ NGADV K T LH+A GH CV LL+ A G+ +A G+ +++ L
Sbjct: 58 DINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDS------KGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHN----------------------ISPLHVATKWGRTNMANLLLSR-------------GAIIDSRTKDLLTPLHCAARSGH-DQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLK---YRAAIEATTESGL--TPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNT-DIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQF--KADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSD-VGAKANNGLTAMHLCAQEDHVP------VAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 2 Score: 172.555 bits (436), Expect = 5.614e-43 Identity = 216/840 (25.71%), Postives = 335/840 (39.88%), Query Frame = 1
Query: 55 NTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCR--------------------------DNKWN---RAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELI----KALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAY---------------------------------GANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDV-LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMI---LSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLL 2364
N N + +L + E S+ +R + + V+ TALH+A+ G S I IL++ G +VN + VNG TPL+ A N V+ L+ GA+ D+K A H+ A + L+L + ++T G T LH A GH V ++LL+ +++ ++ + P+H A G + NLLL A ++ R KD T LH A+ GH +V L+ +GA + T G LH+A+ +H + L+ + + +L L +H + K L+ +R + NSR G T LHI + N + V+LLL Y GANP++ + G++PLH AA NQ +LI+ A V+ Q TPLHIA R G V +LL+ AN+ D P+H+A LLD+ KT L G TPLHLA K N + R+L++ G +D+E + +H AA YN + + LL +NGA+ + K P+H A + LL+ + D +K + +HL+A GH EI L++ S V + +G TA+HL A + H + L + GA+ + + + LH A G ++ + ++ V + R S +PL A Q GH L+ NGA + + G+T L A G+V V+ L
Sbjct: 63 NANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAK-----LLLDR-SADPNSRALNGFTPLHIACK-KNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTL---LTKKGF-----------------------------------TPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNND-KVAMLLLENGASA--------------------KAAAKNGYTPLHIAAKKNQMEIASTLLQF-----------------KADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSD--VGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINS-KTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASY---------TPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 3 Score: 162.155 bits (409), Expect = 8.997e-40 Identity = 198/776 (25.52%), Postives = 337/776 (43.43%), Query Frame = 1
Query: 439 INITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCV-DLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLL------DNVTLK-----------THIN------NLDDDGLGRNL-----VHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNE---AKMDCIKGHVDSSQN---------DYQSKDDVL-----SLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYE 2628
IN ++++G +LH A GH EVV+ L+ + A+ + G +H A+ G I+ +L++N AN+N++ + +T L++A+ H ++V L++ GA T G L +A H +V L++ + + L L + +D D + + E + + G T LHI + H+ V LLL GAN N + + SPLH A + A LL+ A ++ + TPLH A R G+++ V +L+ A ++G+ P+H+A + LL D+VT+ H+ + D R L +H A +K +E +++ I TPLH+A + I L++ GA+ DVE +H AA N+ D++R+L NGA + + +++ P+H A GN D +ILLL+ N + + H+ + + D+ + +L + +HLA+ +G+ E++ L++ + V + ++ T LH+AA+ + LL GA A K+ Y LH AA + N+M ++ L K+ ++ +PL ++ Q GH + LI NG+DV K G T++H HV +L + A+I G ++A G N++ L+ A D EK+ + TPLH AA +GH NC+ L E
Sbjct: 59 INTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKD------DTTAATLLLQNEHNPDVTSKSGFTPLHIAAHY--GHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQT-DVVRVLIRNGAKV--------------------DAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTP--VDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGY-TPLHIAAKK------NQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGA------DVGEKTRASY--------------TPLHQAAQQGHNNCVRYLLE 776 HSP 4 Score: 127.102 bits (318), Expect = 5.309e-29 Identity = 175/730 (23.97%), Postives = 303/730 (41.51%), Query Frame = 1
Query: 1036 ANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDN---GANILSPINI------NDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKS-TNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI 3189
A P G + AA L++ + L++A D+N + + LH+A + G+ + V+ L++ +A A G +H+A+ +AG SL + ++ G +++ + TPL++A + N+ + + L+K GA ++ ED +T +A+ A+ ++ +L +N G L ++I + + N + K P+H A G+ + LLLE KG + +YQ++ ++ S +H+A G + + N L+ + I+ ++ + T LH AA GH V L+ GA +A K+ LH AA VDA ++ ++ VD + +PL +A GH R A+ L+ AD + + G T LH A ++ V+LLL A IE G ++AA G N+++ L+ AN +++++ + TPLH AA T+ + +L ++ + T LH A + + +L+ N T D YS P+ A + L+ HNAD G TP+ +A+K G L + LLLE T + K+ LH A +D +++LE K + N TP H+AA + + L+ F AD K+ P+
Sbjct: 24 AAPEPGRAEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIAS-------------------------------------LAGQSL-IVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAV---ALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLE-----------KG----ANVNYQARHNI-SPLHVATKWGRTNMANLLLSRGA--IIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLA-PLHMAAQGDHVDAARTLLY------HRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANP----------------DVETVRGE----TPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYS--PLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAK----AAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPL 660
BLAST of Ankyrin repeat domain 28b vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0344224) HSP 1 Score: 208.379 bits (529), Expect = 1.136e-53 Identity = 218/803 (27.15%), Postives = 375/803 (46.70%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEEL------IKALNSSHLFLEHLKSNS-HQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGL-GRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEG--DILRLLFDNGANI-------LSPININDHLSFIE------NNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKL 2463
L N +D+N +A ALHLA+ G+ ++ L++ G V+S G T L A + V+ +L+ A N + ++ A N ++L+L + ++ DG T L A+ GH +VV +LL+++T K + +H AA + D++ LLLDND N ++ K +T LHIAS G+ +I LI+KGA+++ + LH+A+ TN+V L I+A L H + S H+ +++ ++ ER I +++ GL LH+ +Q ++ +LL + A + ++ + + LH AA ++ A LL+ AD N + + TPLHIAC+ K V++LL + A+ E G+ P+HVA AF GCM+ + + L H + D + G +H A + ++R G + +QTPLH+A +L N I +L++ GA +D + A+H AA KEG ++ +L +NGA + +P+++ I+ D + GK V P+H A N +LLLE KG + + + + + +H+AA +I L++ + + + + ++G T LHL++ +GHA L+ A K+ +H A + +V+ ++ LE + +D + +PL +A G L+ NGA+VD + G T LH+ GH V+LLL+ A G+ ++A G+ ++L L
Sbjct: 31 LKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDT----RGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVD--------MLLERGAPI-SAKTKNGLAPLHMAAQGEHV-DAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVA-AFM--GCMNIV---IYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAA---KEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLE-----------KG-----ASPHATAKNGHTPLHIAARKNQMDIATTLLEYGA--LANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGL-TPMHLCAQEDNVN------VAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSL 785 HSP 2 Score: 204.142 bits (518), Expect = 2.107e-52 Identity = 223/857 (26.02%), Postives = 376/857 (43.87%), Query Frame = 1
Query: 442 NITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGA-------NILSPINI---NDHLSFIENNIMDNTSLGKKI---VYPVHFAVMSGNFDGMILLLEMMPNEAKMDC--IKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINY--VANKYHQGDF--IEKSHDIFINELKSMWFD---------QDYLTPLHFAASRGHTNCIEMLYE--LSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLL 2922
N DG T+ A G++E V L NN I+ S+ NG+ +H A+ G + +++ LL A ++ K TALHIAS G ++V L+E A ++ + G L++A+ NH +V L+ + L E + L ++ H ++ LES ++R L +LHI ++ D+ + LLL NP++ S++G +PLH A+ A LLI+ ADVN H +PLH+A ++G V +LLE N DG+ P+H CA G + ++ ++ G I + PLH+A + + RIL+ A +D A+H AA + + +LL D A N +P++I + L +E + S+ + P+H A G + +I LL+ ++A D ++G + +HLAA ++I+ L++ ++ V + R +T LH+A+ G+ V LL GA+ A KD Y ALH AA +G + + +V +EN +L D+ + +PL + + GH + A+ L+ ADVD + G T LH A + + LLL+ A G ++AA ++ L+ Y +AN + F + S E+ ++ + ++ LTP+H A + N E+L + + +M + G+ T LH A + +L+ N ++ +TP+ + + + L+ H A+ N Q VNG TP+ IA K G +S L+ L
Sbjct: 5 NGAQGDGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATE----DGFTPLAVAMQQGHDKVVAVLLES--DTRGKVRLPALHIAAKKDDV-KAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLH--------------------------------------CAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAA-HCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQ---HDASPDVPTVRGE---------------TPLHLAARANQTDIIRILLRNGAQ--VDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMY-TALHIAAKEG-----QDEVAAVLIENGAAL-DAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGY-TPLHVASHFGQANMVRFLLQNGAN--VDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSL 785 HSP 3 Score: 169.088 bits (427), Expect = 1.294e-41 Identity = 141/537 (26.26%), Postives = 237/537 (44.13%), Query Frame = 1
Query: 106 DGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPININDHLSFI 1695
D R LY++ V+ TALH+AA+ G+ +A +L+ D N++ +NG TPL AC N V+ +L+ GA + HV A ++ + +L H ++ G T LH A ++++ILL N + A + P+H A+ G+++I+ LLL + A ++ KD YTALHIA+ G ++ LIE GA LD T +G HL ++ Q L+++ E+ ++++ G+T LH+ +N Q LLL GA+P+ ++NG +PLH AA +NQ+ A L++ A N + TPLH++ + G+ + +L+E+KA ++G+ P+H+ C + DNV + E + + G +I TPLH+A + R L++ GA++D +H A I+ LL ++ AN +P++I L +I
Sbjct: 318 DAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKG----------------------FTPLHLTAKYGHIKVAQLLLQK-------------EADVDAQGKNGVTPLHVACHYNN-QQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHL--------CAQE--DNVNVA----------------------------EILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQ-QGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYI 779 HSP 4 Score: 119.398 bits (298), Expect = 1.590e-26 Identity = 164/709 (23.13%), Postives = 288/709 (40.62%), Query Frame = 1
Query: 1060 NGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDN---GANILSPINI---NDHL---SFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLIN----------------YVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFM-TFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAA 3102
+G + AA L++ + +K D+N + + LH+A + G+ V LL A ++D+ T K G +H A G + ++ ++ ++ + TPL++A + N+ + R+L+ GA S+ ED +T +A+ AM ++ +L ++ G L ++I D + + + +N + K P+H A GN + LL++ KG + +Y +K ++ S +H+AA G + +++ L++ + + R G T LH AA GH V LL GA +A K+ LH AA VDA ++ ++ VD + + L +A GH R A+ L+ AD + + G T LH A ++ V+LLL A I G ++AA G N+++ L+ ++A + +Q D I + N + ++ TPLH A+ G+ + + +L + ++ +T M T LH A DE + I N ++ K +TP+ ++ + L+ AD++ Q NG TP+ +A LLLE A K+ LH A + +LE L N+ TP HL++
Sbjct: 10 DGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGA---------------------------IVDSATKK-----------GNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAV---AMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQ-----------KG----ADVNYSAKHNI-SPLHVAAKWGKTNMVSLLLE--KGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGL-APLHMAAQGEHVDAARILLY------HRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRI---LLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEV--AAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATA-KNGHTPLHIAARKNQMDIATTLLE----YGALANAESKAGFTPLHLSS 642 HSP 5 Score: 118.627 bits (296), Expect = 2.797e-26 Identity = 102/368 (27.72%), Postives = 161/368 (43.75%), Query Frame = 1
Query: 97 SDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGY 1200
+ +D +R L N V+ + QT LH+A+ +GN +I +L+++G V++ + T L A V VLI +GA + K H+ A + + +L+L ++ +G T LH A + +V +LL+ S A+ KNG P+H AA + ++I LL+ A N K +T LH++S GH +I LIE A ++ G L HL + N + I E+ + ++ G T LH+ S A+ V LL GAN + + G +PLH A + LL++ KA+ N Q + TPLHIA + GY
Sbjct: 447 NQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNG----------------------LTPMHLCAQEDNVNVAE-------------ILEKNGANIDMATKAGYTPLHVASHFGQANM-VRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGY 778 HSP 6 Score: 101.679 bits (252), Expect = 4.983e-21 Identity = 125/487 (25.67%), Postives = 205/487 (42.09%), Query Frame = 1
Query: 1840 HVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRT---SLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLI------NY----------VANKYHQGDFI----EKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEM--KSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEK---LPCLKKLINSLDNNQ---------QTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI 3189
H+ ++ + S + L+ +HLA+ GH +++ L++ IV + + G TALH+A+ G VK LL A ++ + Y A+Q + DA+ ++LS + D +PL +A+Q GH + L+ + DT G+ +LH A V+ LLLD + ++ G ++A+ G++N+ LI NY VA K+ + + + EK +I E K+ +D LTPLH AA GH ++ML E + K+ NG A D + A D + T + A H +V + L+ NAD N + +NG TP+ IA K+ L + LLL H A SA G+ L + C+ +I L ++ +TP HLAA + + L+ GA + + + Q P+
Sbjct: 30 HLKNNIDINTSNANGLNALHLASKDGHIHVVSELLR--RGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGF--TPLYMAAQENHDAVVRLLLSNGANQSLATEDGF-----TPLAVAMQQGHDKVVAVLLES-------DTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNI---EAKT----RDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVD---YLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLR-----------------HGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPL 473 HSP 7 Score: 76.2554 bits (186), Expect = 2.082e-13 Identity = 59/200 (29.50%), Postives = 97/200 (48.50%), Query Frame = 1
Query: 166 QTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIV--IRLIEKGAELDCVTTQG 759
T LH+AA +IA L++YG N++ G TPL + + +LI A N H+CA ++V+ +++ + I++ G T LH A G +V+ LL N ++ A+ G P+H A +G I+NLLL++ AN N + + T LHIA +G+I ++ ++ I K E +Q
Sbjct: 602 HTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQA 801
BLAST of Ankyrin repeat domain 28b vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303125) HSP 1 Score: 208.379 bits (529), Expect = 1.150e-53 Identity = 218/803 (27.15%), Postives = 375/803 (46.70%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEEL------IKALNSSHLFLEHLKSNS-HQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGL-GRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEG--DILRLLFDNGANI-------LSPININDHLSFIE------NNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKL 2463
L N +D+N +A ALHLA+ G+ ++ L++ G V+S G T L A + V+ +L+ A N + ++ A N ++L+L + ++ DG T L A+ GH +VV +LL+++T K + +H AA + D++ LLLDND N ++ K +T LHIAS G+ +I LI+KGA+++ + LH+A+ TN+V L I+A L H + S H+ +++ ++ ER I +++ GL LH+ +Q ++ +LL + A + ++ + + LH AA ++ A LL+ AD N + + TPLHIAC+ K V++LL + A+ E G+ P+HVA AF GCM+ + + L H + D + G +H A + ++R G + +QTPLH+A +L N I +L++ GA +D + A+H AA KEG ++ +L +NGA + +P+++ I+ D + GK V P+H A N +LLLE KG + + + + + +H+AA +I L++ + + + + ++G T LHL++ +GHA L+ A K+ +H A + +V+ ++ LE + +D + +PL +A G L+ NGA+VD + G T LH+ GH V+LLL+ A G+ ++A G+ ++L L
Sbjct: 31 LKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDT----RGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVD--------MLLERGAPI-SAKTKNGLAPLHMAAQGEHV-DAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVA-AFM--GCMNIV---IYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAA---KEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLE-----------KG-----ASPHATAKNGHTPLHIAARKNQMDIATTLLEYGA--LANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGL-TPMHLCAQEDNVN------VAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSL 785 HSP 2 Score: 204.142 bits (518), Expect = 2.132e-52 Identity = 223/857 (26.02%), Postives = 376/857 (43.87%), Query Frame = 1
Query: 442 NITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGA-------NILSPINI---NDHLSFIENNIMDNTSLGKKI---VYPVHFAVMSGNFDGMILLLEMMPNEAKMDC--IKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINY--VANKYHQGDF--IEKSHDIFINELKSMWFD---------QDYLTPLHFAASRGHTNCIEMLYE--LSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLL 2922
N DG T+ A G++E V L NN I+ S+ NG+ +H A+ G + +++ LL A ++ K TALHIAS G ++V L+E A ++ + G L++A+ NH +V L+ + L E + L ++ H ++ LES ++R L +LHI ++ D+ + LLL NP++ S++G +PLH A+ A LLI+ ADVN H +PLH+A ++G V +LLE N DG+ P+H CA G + ++ ++ G I + PLH+A + + RIL+ A +D A+H AA + + +LL D A N +P++I + L +E + S+ + P+H A G + +I LL+ ++A D ++G + +HLAA ++I+ L++ ++ V + R +T LH+A+ G+ V LL GA+ A KD Y ALH AA +G + + +V +EN +L D+ + +PL + + GH + A+ L+ ADVD + G T LH A + + LLL+ A G ++AA ++ L+ Y +AN + F + S E+ ++ + ++ LTP+H A + N E+L + + +M + G+ T LH A + +L+ N ++ +TP+ + + + L+ H A+ N Q VNG TP+ IA K G +S L+ L
Sbjct: 5 NGAQGDGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATE----DGFTPLAVAMQQGHDKVVAVLLES--DTRGKVRLPALHIAAKKDDV-KAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLH--------------------------------------CAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAA-HCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQ---HDASPDVPTVRGE---------------TPLHLAARANQTDIIRILLRNGAQ--VDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMY-TALHIAAKEG-----QDEVAAVLIENGAAL-DAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGY-TPLHVASHFGQANMVRFLLQNGAN--VDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSL 785 HSP 3 Score: 169.088 bits (427), Expect = 1.306e-41 Identity = 141/537 (26.26%), Postives = 237/537 (44.13%), Query Frame = 1
Query: 106 DGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPININDHLSFI 1695
D R LY++ V+ TALH+AA+ G+ +A +L+ D N++ +NG TPL AC N V+ +L+ GA + HV A ++ + +L H ++ G T LH A ++++ILL N + A + P+H A+ G+++I+ LLL + A ++ KD YTALHIA+ G ++ LIE GA LD T +G HL ++ Q L+++ E+ ++++ G+T LH+ +N Q LLL GA+P+ ++NG +PLH AA +NQ+ A L++ A N + TPLH++ + G+ + +L+E+KA ++G+ P+H+ C + DNV + E + + G +I TPLH+A + R L++ GA++D +H A I+ LL ++ AN +P++I L +I
Sbjct: 318 DAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKG----------------------FTPLHLTAKYGHIKVAQLLLQK-------------EADVDAQGKNGVTPLHVACHYNN-QQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHL--------CAQE--DNVNVA----------------------------EILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQ-QGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYI 779 HSP 4 Score: 119.398 bits (298), Expect = 1.601e-26 Identity = 164/709 (23.13%), Postives = 288/709 (40.62%), Query Frame = 1
Query: 1060 NGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDN---GANILSPINI---NDHL---SFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLIN----------------YVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFM-TFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAA 3102
+G + AA L++ + +K D+N + + LH+A + G+ V LL A ++D+ T K G +H A G + ++ ++ ++ + TPL++A + N+ + R+L+ GA S+ ED +T +A+ AM ++ +L ++ G L ++I D + + + +N + K P+H A GN + LL++ KG + +Y +K ++ S +H+AA G + +++ L++ + + R G T LH AA GH V LL GA +A K+ LH AA VDA ++ ++ VD + + L +A GH R A+ L+ AD + + G T LH A ++ V+LLL A I G ++AA G N+++ L+ ++A + +Q D I + N + ++ TPLH A+ G+ + + +L + ++ +T M T LH A DE + I N ++ K +TP+ ++ + L+ AD++ Q NG TP+ +A LLLE A K+ LH A + +LE L N+ TP HL++
Sbjct: 10 DGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGA---------------------------IVDSATKK-----------GNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAV---AMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQ-----------KG----ADVNYSAKHNI-SPLHVAAKWGKTNMVSLLLE--KGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGL-APLHMAAQGEHVDAARILLY------HRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRI---LLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEV--AAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATA-KNGHTPLHIAARKNQMDIATTLLE----YGALANAESKAGFTPLHLSS 642 HSP 5 Score: 118.627 bits (296), Expect = 2.816e-26 Identity = 102/368 (27.72%), Postives = 161/368 (43.75%), Query Frame = 1
Query: 97 SDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGY 1200
+ +D +R L N V+ + QT LH+A+ +GN +I +L+++G V++ + T L A V VLI +GA + K H+ A + + +L+L ++ +G T LH A + +V +LL+ S A+ KNG P+H AA + ++I LL+ A N K +T LH++S GH +I LIE A ++ G L HL + N + I E+ + ++ G T LH+ S A+ V LL GAN + + G +PLH A + LL++ KA+ N Q + TPLHIA + GY
Sbjct: 447 NQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNG----------------------LTPMHLCAQEDNVNVAE-------------ILEKNGANIDMATKAGYTPLHVASHFGQANM-VRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGY 778 HSP 6 Score: 101.679 bits (252), Expect = 5.011e-21 Identity = 125/487 (25.67%), Postives = 205/487 (42.09%), Query Frame = 1
Query: 1840 HVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRT---SLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLI------NY----------VANKYHQGDFI----EKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEM--KSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEK---LPCLKKLINSLDNNQ---------QTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI 3189
H+ ++ + S + L+ +HLA+ GH +++ L++ IV + + G TALH+A+ G VK LL A ++ + Y A+Q + DA+ ++LS + D +PL +A+Q GH + L+ + DT G+ +LH A V+ LLLD + ++ G ++A+ G++N+ LI NY VA K+ + + + EK +I E K+ +D LTPLH AA GH ++ML E + K+ NG A D + A D + T + A H +V + L+ NAD N + +NG TP+ IA K+ L + LLL H A SA G+ L + C+ +I L ++ +TP HLAA + + L+ GA + + + Q P+
Sbjct: 30 HLKNNIDINTSNANGLNALHLASKDGHIHVVSELLR--RGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGF--TPLYMAAQENHDAVVRLLLSNGANQSLATEDGF-----TPLAVAMQQGHDKVVAVLLES-------DTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNI---EAKT----RDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVD---YLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLR-----------------HGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPL 473 HSP 7 Score: 76.2554 bits (186), Expect = 2.090e-13 Identity = 59/200 (29.50%), Postives = 97/200 (48.50%), Query Frame = 1
Query: 166 QTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIV--IRLIEKGAELDCVTTQG 759
T LH+AA +IA L++YG N++ G TPL + + +LI A N H+CA ++V+ +++ + I++ G T LH A G +V+ LL N ++ A+ G P+H A +G I+NLLL++ AN N + + T LHIA +G+I ++ ++ I K E +Q
Sbjct: 602 HTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQA 801
BLAST of Ankyrin repeat domain 28b vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303121) HSP 1 Score: 206.068 bits (523), Expect = 4.878e-53 Identity = 218/803 (27.15%), Postives = 375/803 (46.70%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEEL------IKALNSSHLFLEHLKSNS-HQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGL-GRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEG--DILRLLFDNGANI-------LSPININDHLSFIE------NNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKL 2463
L N +D+N +A ALHLA+ G+ ++ L++ G V+S G T L A + V+ +L+ A N + ++ A N ++L+L + ++ DG T L A+ GH +VV +LL+++T K + +H AA + D++ LLLDND N ++ K +T LHIAS G+ +I LI+KGA+++ + LH+A+ TN+V L I+A L H + S H+ +++ ++ ER I +++ GL LH+ +Q ++ +LL + A + ++ + + LH AA ++ A LL+ AD N + + TPLHIAC+ K V++LL + A+ E G+ P+HVA AF GCM+ + + L H + D + G +H A + ++R G + +QTPLH+A +L N I +L++ GA +D + A+H AA KEG ++ +L +NGA + +P+++ I+ D + GK V P+H A N +LLLE KG + + + + + +H+AA +I L++ + + + + ++G T LHL++ +GHA L+ A K+ +H A + +V+ ++ LE + +D + +PL +A G L+ NGA+VD + G T LH+ GH V+LLL+ A G+ ++A G+ ++L L
Sbjct: 31 LKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDT----RGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVD--------MLLERGAPI-SAKTKNGLAPLHMAAQGEHV-DAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVA-AFM--GCMNIV---IYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAA---KEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLE-----------KG-----ASPHATAKNGHTPLHIAARKNQMDIATTLLEYGA--LANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGL-TPMHLCAQEDNVN------VAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSL 785 HSP 2 Score: 201.83 bits (512), Expect = 9.535e-52 Identity = 223/857 (26.02%), Postives = 376/857 (43.87%), Query Frame = 1
Query: 442 NITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGA-------NILSPINI---NDHLSFIENNIMDNTSLGKKI---VYPVHFAVMSGNFDGMILLLEMMPNEAKMDC--IKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINY--VANKYHQGDF--IEKSHDIFINELKSMWFD---------QDYLTPLHFAASRGHTNCIEMLYE--LSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLL 2922
N DG T+ A G++E V L NN I+ S+ NG+ +H A+ G + +++ LL A ++ K TALHIAS G ++V L+E A ++ + G L++A+ NH +V L+ + L E + L ++ H ++ LES ++R L +LHI ++ D+ + LLL NP++ S++G +PLH A+ A LLI+ ADVN H +PLH+A ++G V +LLE N DG+ P+H CA G + ++ ++ G I + PLH+A + + RIL+ A +D A+H AA + + +LL D A N +P++I + L +E + S+ + P+H A G + +I LL+ ++A D ++G + +HLAA ++I+ L++ ++ V + R +T LH+A+ G+ V LL GA+ A KD Y ALH AA +G + + +V +EN +L D+ + +PL + + GH + A+ L+ ADVD + G T LH A + + LLL+ A G ++AA ++ L+ Y +AN + F + S E+ ++ + ++ LTP+H A + N E+L + + +M + G+ T LH A + +L+ N ++ +TP+ + + + L+ H A+ N Q VNG TP+ IA K G +S L+ L
Sbjct: 5 NGAQGDGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATE----DGFTPLAVAMQQGHDKVVAVLLES--DTRGKVRLPALHIAAKKDDV-KAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLH--------------------------------------CAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAA-HCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQ---HDASPDVPTVRGE---------------TPLHLAARANQTDIIRILLRNGAQ--VDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMY-TALHIAAKEG-----QDEVAAVLIENGAAL-DAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGY-TPLHVASHFGQANMVRFLLQNGAN--VDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSL 785 HSP 3 Score: 167.548 bits (423), Expect = 3.646e-41 Identity = 141/537 (26.26%), Postives = 237/537 (44.13%), Query Frame = 1
Query: 106 DGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPININDHLSFI 1695
D R LY++ V+ TALH+AA+ G+ +A +L+ D N++ +NG TPL AC N V+ +L+ GA + HV A ++ + +L H ++ G T LH A ++++ILL N + A + P+H A+ G+++I+ LLL + A ++ KD YTALHIA+ G ++ LIE GA LD T +G HL ++ Q L+++ E+ ++++ G+T LH+ +N Q LLL GA+P+ ++NG +PLH AA +NQ+ A L++ A N + TPLH++ + G+ + +L+E+KA ++G+ P+H+ C + DNV + E + + G +I TPLH+A + R L++ GA++D +H A I+ LL ++ AN +P++I L +I
Sbjct: 318 DAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKG----------------------FTPLHLTAKYGHIKVAQLLLQK-------------EADVDAQGKNGVTPLHVACHYNN-QQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHL--------CAQE--DNVNVA----------------------------EILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQ-QGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYI 779 HSP 4 Score: 117.857 bits (294), Expect = 5.198e-26 Identity = 102/368 (27.72%), Postives = 161/368 (43.75%), Query Frame = 1
Query: 97 SDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGY 1200
+ +D +R L N V+ + QT LH+A+ +GN +I +L+++G V++ + T L A V VLI +GA + K H+ A + + +L+L ++ +G T LH A + +V +LL+ S A+ KNG P+H AA + ++I LL+ A N K +T LH++S GH +I LIE A ++ G L HL + N + I E+ + ++ G T LH+ S A+ V LL GAN + + G +PLH A + LL++ KA+ N Q + TPLHIA + GY
Sbjct: 447 NQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNG----------------------LTPMHLCAQEDNVNVAE-------------ILEKNGANIDMATKAGYTPLHVASHFGQANM-VRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGY 778 HSP 5 Score: 117.472 bits (293), Expect = 6.050e-26 Identity = 164/709 (23.13%), Postives = 288/709 (40.62%), Query Frame = 1
Query: 1060 NGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDN---GANILSPINI---NDHL---SFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLIN----------------YVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFM-TFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAA 3102
+G + AA L++ + +K D+N + + LH+A + G+ V LL A ++D+ T K G +H A G + ++ ++ ++ + TPL++A + N+ + R+L+ GA S+ ED +T +A+ AM ++ +L ++ G L ++I D + + + +N + K P+H A GN + LL++ KG + +Y +K ++ S +H+AA G + +++ L++ + + R G T LH AA GH V LL GA +A K+ LH AA VDA ++ ++ VD + + L +A GH R A+ L+ AD + + G T LH A ++ V+LLL A I G ++AA G N+++ L+ ++A + +Q D I + N + ++ TPLH A+ G+ + + +L + ++ +T M T LH A DE + I N ++ K +TP+ ++ + L+ AD++ Q NG TP+ +A LLLE A K+ LH A + +LE L N+ TP HL++
Sbjct: 10 DGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGA---------------------------IVDSATKK-----------GNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAV---AMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQ-----------KG----ADVNYSAKHNI-SPLHVAAKWGKTNMVSLLLE--KGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGL-APLHMAAQGEHVDAARILLY------HRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRI---LLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEV--AAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATA-KNGHTPLHIAARKNQMDIATTLLE----YGALANAESKAGFTPLHLSS 642 HSP 6 Score: 100.138 bits (248), Expect = 1.305e-20 Identity = 125/487 (25.67%), Postives = 205/487 (42.09%), Query Frame = 1
Query: 1840 HVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRT---SLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLI------NY----------VANKYHQGDFI----EKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEM--KSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEK---LPCLKKLINSLDNNQ---------QTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI 3189
H+ ++ + S + L+ +HLA+ GH +++ L++ IV + + G TALH+A+ G VK LL A ++ + Y A+Q + DA+ ++LS + D +PL +A+Q GH + L+ + DT G+ +LH A V+ LLLD + ++ G ++A+ G++N+ LI NY VA K+ + + + EK +I E K+ +D LTPLH AA GH ++ML E + K+ NG A D + A D + T + A H +V + L+ NAD N + +NG TP+ IA K+ L + LLL H A SA G+ L + C+ +I L ++ +TP HLAA + + L+ GA + + + Q P+
Sbjct: 30 HLKNNIDINTSNANGLNALHLASKDGHIHVVSELLR--RGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGF--TPLYMAAQENHDAVVRLLLSNGANQSLATEDGF-----TPLAVAMQQGHDKVVAVLLES-------DTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNI---EAKT----RDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVD---YLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLR-----------------HGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPL 473 HSP 7 Score: 75.8702 bits (185), Expect = 2.812e-13 Identity = 59/200 (29.50%), Postives = 97/200 (48.50%), Query Frame = 1
Query: 166 QTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIV--IRLIEKGAELDCVTTQG 759
T LH+AA +IA L++YG N++ G TPL + + +LI A N H+CA ++V+ +++ + I++ G T LH A G +V+ LL N ++ A+ G P+H A +G I+NLLL++ AN N + + T LHIA +G+I ++ ++ I K E +Q
Sbjct: 602 HTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQA 801
BLAST of Ankyrin repeat domain 28b vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303117) HSP 1 Score: 206.068 bits (523), Expect = 4.910e-53 Identity = 218/803 (27.15%), Postives = 375/803 (46.70%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEEL------IKALNSSHLFLEHLKSNS-HQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGL-GRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEG--DILRLLFDNGANI-------LSPININDHLSFIE------NNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKL 2463
L N +D+N +A ALHLA+ G+ ++ L++ G V+S G T L A + V+ +L+ A N + ++ A N ++L+L + ++ DG T L A+ GH +VV +LL+++T K + +H AA + D++ LLLDND N ++ K +T LHIAS G+ +I LI+KGA+++ + LH+A+ TN+V L I+A L H + S H+ +++ ++ ER I +++ GL LH+ +Q ++ +LL + A + ++ + + LH AA ++ A LL+ AD N + + TPLHIAC+ K V++LL + A+ E G+ P+HVA AF GCM+ + + L H + D + G +H A + ++R G + +QTPLH+A +L N I +L++ GA +D + A+H AA KEG ++ +L +NGA + +P+++ I+ D + GK V P+H A N +LLLE KG + + + + + +H+AA +I L++ + + + + ++G T LHL++ +GHA L+ A K+ +H A + +V+ ++ LE + +D + +PL +A G L+ NGA+VD + G T LH+ GH V+LLL+ A G+ ++A G+ ++L L
Sbjct: 31 LKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDT----RGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVD--------MLLERGAPI-SAKTKNGLAPLHMAAQGEHV-DAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVA-AFM--GCMNIV---IYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAA---KEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLE-----------KG-----ASPHATAKNGHTPLHIAARKNQMDIATTLLEYGA--LANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGL-TPMHLCAQEDNVN------VAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSL 785 HSP 2 Score: 201.83 bits (512), Expect = 9.597e-52 Identity = 223/857 (26.02%), Postives = 376/857 (43.87%), Query Frame = 1
Query: 442 NITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGA-------NILSPINI---NDHLSFIENNIMDNTSLGKKI---VYPVHFAVMSGNFDGMILLLEMMPNEAKMDC--IKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINY--VANKYHQGDF--IEKSHDIFINELKSMWFD---------QDYLTPLHFAASRGHTNCIEMLYE--LSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLL 2922
N DG T+ A G++E V L NN I+ S+ NG+ +H A+ G + +++ LL A ++ K TALHIAS G ++V L+E A ++ + G L++A+ NH +V L+ + L E + L ++ H ++ LES ++R L +LHI ++ D+ + LLL NP++ S++G +PLH A+ A LLI+ ADVN H +PLH+A ++G V +LLE N DG+ P+H CA G + ++ ++ G I + PLH+A + + RIL+ A +D A+H AA + + +LL D A N +P++I + L +E + S+ + P+H A G + +I LL+ ++A D ++G + +HLAA ++I+ L++ ++ V + R +T LH+A+ G+ V LL GA+ A KD Y ALH AA +G + + +V +EN +L D+ + +PL + + GH + A+ L+ ADVD + G T LH A + + LLL+ A G ++AA ++ L+ Y +AN + F + S E+ ++ + ++ LTP+H A + N E+L + + +M + G+ T LH A + +L+ N ++ +TP+ + + + L+ H A+ N Q VNG TP+ IA K G +S L+ L
Sbjct: 5 NGAQGDGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATE----DGFTPLAVAMQQGHDKVVAVLLES--DTRGKVRLPALHIAAKKDDV-KAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLH--------------------------------------CAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAA-HCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQ---HDASPDVPTVRGE---------------TPLHLAARANQTDIIRILLRNGAQ--VDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMY-TALHIAAKEG-----QDEVAAVLIENGAAL-DAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGY-TPLHVASHFGQANMVRFLLQNGAN--VDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSL 785 HSP 3 Score: 167.548 bits (423), Expect = 3.702e-41 Identity = 141/537 (26.26%), Postives = 237/537 (44.13%), Query Frame = 1
Query: 106 DGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPININDHLSFI 1695
D R LY++ V+ TALH+AA+ G+ +A +L+ D N++ +NG TPL AC N V+ +L+ GA + HV A ++ + +L H ++ G T LH A ++++ILL N + A + P+H A+ G+++I+ LLL + A ++ KD YTALHIA+ G ++ LIE GA LD T +G HL ++ Q L+++ E+ ++++ G+T LH+ +N Q LLL GA+P+ ++NG +PLH AA +NQ+ A L++ A N + TPLH++ + G+ + +L+E+KA ++G+ P+H+ C + DNV + E + + G +I TPLH+A + R L++ GA++D +H A I+ LL ++ AN +P++I L +I
Sbjct: 318 DAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKG----------------------FTPLHLTAKYGHIKVAQLLLQK-------------EADVDAQGKNGVTPLHVACHYNN-QQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHL--------CAQE--DNVNVA----------------------------EILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQ-QGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYI 779 HSP 4 Score: 117.857 bits (294), Expect = 5.148e-26 Identity = 102/368 (27.72%), Postives = 161/368 (43.75%), Query Frame = 1
Query: 97 SDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGY 1200
+ +D +R L N V+ + QT LH+A+ +GN +I +L+++G V++ + T L A V VLI +GA + K H+ A + + +L+L ++ +G T LH A + +V +LL+ S A+ KNG P+H AA + ++I LL+ A N K +T LH++S GH +I LIE A ++ G L HL + N + I E+ + ++ G T LH+ S A+ V LL GAN + + G +PLH A + LL++ KA+ N Q + TPLHIA + GY
Sbjct: 447 NQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNG----------------------LTPMHLCAQEDNVNVAE-------------ILEKNGANIDMATKAGYTPLHVASHFGQANM-VRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGY 778 HSP 5 Score: 117.472 bits (293), Expect = 5.993e-26 Identity = 164/709 (23.13%), Postives = 288/709 (40.62%), Query Frame = 1
Query: 1060 NGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDN---GANILSPINI---NDHL---SFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLIN----------------YVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFM-TFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAA 3102
+G + AA L++ + +K D+N + + LH+A + G+ V LL A ++D+ T K G +H A G + ++ ++ ++ + TPL++A + N+ + R+L+ GA S+ ED +T +A+ AM ++ +L ++ G L ++I D + + + +N + K P+H A GN + LL++ KG + +Y +K ++ S +H+AA G + +++ L++ + + R G T LH AA GH V LL GA +A K+ LH AA VDA ++ ++ VD + + L +A GH R A+ L+ AD + + G T LH A ++ V+LLL A I G ++AA G N+++ L+ ++A + +Q D I + N + ++ TPLH A+ G+ + + +L + ++ +T M T LH A DE + I N ++ K +TP+ ++ + L+ AD++ Q NG TP+ +A LLLE A K+ LH A + +LE L N+ TP HL++
Sbjct: 10 DGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGA---------------------------IVDSATKK-----------GNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAV---AMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQ-----------KG----ADVNYSAKHNI-SPLHVAAKWGKTNMVSLLLE--KGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGL-APLHMAAQGEHVDAARILLY------HRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRI---LLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEV--AAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATA-KNGHTPLHIAARKNQMDIATTLLE----YGALANAESKAGFTPLHLSS 642 HSP 6 Score: 100.138 bits (248), Expect = 1.315e-20 Identity = 125/487 (25.67%), Postives = 205/487 (42.09%), Query Frame = 1
Query: 1840 HVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRT---SLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLI------NY----------VANKYHQGDFI----EKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEM--KSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEK---LPCLKKLINSLDNNQ---------QTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI 3189
H+ ++ + S + L+ +HLA+ GH +++ L++ IV + + G TALH+A+ G VK LL A ++ + Y A+Q + DA+ ++LS + D +PL +A+Q GH + L+ + DT G+ +LH A V+ LLLD + ++ G ++A+ G++N+ LI NY VA K+ + + + EK +I E K+ +D LTPLH AA GH ++ML E + K+ NG A D + A D + T + A H +V + L+ NAD N + +NG TP+ IA K+ L + LLL H A SA G+ L + C+ +I L ++ +TP HLAA + + L+ GA + + + Q P+
Sbjct: 30 HLKNNIDINTSNANGLNALHLASKDGHIHVVSELLR--RGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGF--TPLYMAAQENHDAVVRLLLSNGANQSLATEDGF-----TPLAVAMQQGHDKVVAVLLES-------DTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNI---EAKT----RDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVD---YLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLR-----------------HGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPL 473 HSP 7 Score: 75.8702 bits (185), Expect = 2.834e-13 Identity = 59/200 (29.50%), Postives = 97/200 (48.50%), Query Frame = 1
Query: 166 QTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIV--IRLIEKGAELDCVTTQG 759
T LH+AA +IA L++YG N++ G TPL + + +LI A N H+CA ++V+ +++ + I++ G T LH A G +V+ LL N ++ A+ G P+H A +G I+NLLL++ AN N + + T LHIA +G+I ++ ++ I K E +Q
Sbjct: 602 HTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQA 801
BLAST of Ankyrin repeat domain 28b vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303123) HSP 1 Score: 206.068 bits (523), Expect = 5.073e-53 Identity = 218/803 (27.15%), Postives = 375/803 (46.70%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEEL------IKALNSSHLFLEHLKSNS-HQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGL-GRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEG--DILRLLFDNGANI-------LSPININDHLSFIE------NNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKL 2463
L N +D+N +A ALHLA+ G+ ++ L++ G V+S G T L A + V+ +L+ A N + ++ A N ++L+L + ++ DG T L A+ GH +VV +LL+++T K + +H AA + D++ LLLDND N ++ K +T LHIAS G+ +I LI+KGA+++ + LH+A+ TN+V L I+A L H + S H+ +++ ++ ER I +++ GL LH+ +Q ++ +LL + A + ++ + + LH AA ++ A LL+ AD N + + TPLHIAC+ K V++LL + A+ E G+ P+HVA AF GCM+ + + L H + D + G +H A + ++R G + +QTPLH+A +L N I +L++ GA +D + A+H AA KEG ++ +L +NGA + +P+++ I+ D + GK V P+H A N +LLLE KG + + + + + +H+AA +I L++ + + + + ++G T LHL++ +GHA L+ A K+ +H A + +V+ ++ LE + +D + +PL +A G L+ NGA+VD + G T LH+ GH V+LLL+ A G+ ++A G+ ++L L
Sbjct: 31 LKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDT----RGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVD--------MLLERGAPI-SAKTKNGLAPLHMAAQGEHV-DAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVA-AFM--GCMNIV---IYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAA---KEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLE-----------KG-----ASPHATAKNGHTPLHIAARKNQMDIATTLLEYGA--LANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGL-TPMHLCAQEDNVN------VAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSL 785 HSP 2 Score: 201.83 bits (512), Expect = 9.747e-52 Identity = 223/857 (26.02%), Postives = 376/857 (43.87%), Query Frame = 1
Query: 442 NITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGA-------NILSPINI---NDHLSFIENNIMDNTSLGKKI---VYPVHFAVMSGNFDGMILLLEMMPNEAKMDC--IKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINY--VANKYHQGDF--IEKSHDIFINELKSMWFD---------QDYLTPLHFAASRGHTNCIEMLYE--LSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLL 2922
N DG T+ A G++E V L NN I+ S+ NG+ +H A+ G + +++ LL A ++ K TALHIAS G ++V L+E A ++ + G L++A+ NH +V L+ + L E + L ++ H ++ LES ++R L +LHI ++ D+ + LLL NP++ S++G +PLH A+ A LLI+ ADVN H +PLH+A ++G V +LLE N DG+ P+H CA G + ++ ++ G I + PLH+A + + RIL+ A +D A+H AA + + +LL D A N +P++I + L +E + S+ + P+H A G + +I LL+ ++A D ++G + +HLAA ++I+ L++ ++ V + R +T LH+A+ G+ V LL GA+ A KD Y ALH AA +G + + +V +EN +L D+ + +PL + + GH + A+ L+ ADVD + G T LH A + + LLL+ A G ++AA ++ L+ Y +AN + F + S E+ ++ + ++ LTP+H A + N E+L + + +M + G+ T LH A + +L+ N ++ +TP+ + + + L+ H A+ N Q VNG TP+ IA K G +S L+ L
Sbjct: 5 NGAQGDGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATE----DGFTPLAVAMQQGHDKVVAVLLES--DTRGKVRLPALHIAAKKDDV-KAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLH--------------------------------------CAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAA-HCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQ---HDASPDVPTVRGE---------------TPLHLAARANQTDIIRILLRNGAQ--VDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMY-TALHIAAKEG-----QDEVAAVLIENGAAL-DAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGY-TPLHVASHFGQANMVRFLLQNGAN--VDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSL 785 HSP 3 Score: 167.548 bits (423), Expect = 3.754e-41 Identity = 141/537 (26.26%), Postives = 237/537 (44.13%), Query Frame = 1
Query: 106 DGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPININDHLSFI 1695
D R LY++ V+ TALH+AA+ G+ +A +L+ D N++ +NG TPL AC N V+ +L+ GA + HV A ++ + +L H ++ G T LH A ++++ILL N + A + P+H A+ G+++I+ LLL + A ++ KD YTALHIA+ G ++ LIE GA LD T +G HL ++ Q L+++ E+ ++++ G+T LH+ +N Q LLL GA+P+ ++NG +PLH AA +NQ+ A L++ A N + TPLH++ + G+ + +L+E+KA ++G+ P+H+ C + DNV + E + + G +I TPLH+A + R L++ GA++D +H A I+ LL ++ AN +P++I L +I
Sbjct: 318 DAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKG----------------------FTPLHLTAKYGHIKVAQLLLQK-------------EADVDAQGKNGVTPLHVACHYNN-QQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHL--------CAQE--DNVNVA----------------------------EILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQ-QGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYI 779 HSP 4 Score: 117.857 bits (294), Expect = 5.255e-26 Identity = 102/368 (27.72%), Postives = 161/368 (43.75%), Query Frame = 1
Query: 97 SDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGY 1200
+ +D +R L N V+ + QT LH+A+ +GN +I +L+++G V++ + T L A V VLI +GA + K H+ A + + +L+L ++ +G T LH A + +V +LL+ S A+ KNG P+H AA + ++I LL+ A N K +T LH++S GH +I LIE A ++ G L HL + N + I E+ + ++ G T LH+ S A+ V LL GAN + + G +PLH A + LL++ KA+ N Q + TPLHIA + GY
Sbjct: 447 NQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNG----------------------LTPMHLCAQEDNVNVAE-------------ILEKNGANIDMATKAGYTPLHVASHFGQANM-VRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGY 778 HSP 5 Score: 117.472 bits (293), Expect = 6.117e-26 Identity = 164/709 (23.13%), Postives = 288/709 (40.62%), Query Frame = 1
Query: 1060 NGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDN---GANILSPINI---NDHL---SFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLIN----------------YVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFM-TFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAA 3102
+G + AA L++ + +K D+N + + LH+A + G+ V LL A ++D+ T K G +H A G + ++ ++ ++ + TPL++A + N+ + R+L+ GA S+ ED +T +A+ AM ++ +L ++ G L ++I D + + + +N + K P+H A GN + LL++ KG + +Y +K ++ S +H+AA G + +++ L++ + + R G T LH AA GH V LL GA +A K+ LH AA VDA ++ ++ VD + + L +A GH R A+ L+ AD + + G T LH A ++ V+LLL A I G ++AA G N+++ L+ ++A + +Q D I + N + ++ TPLH A+ G+ + + +L + ++ +T M T LH A DE + I N ++ K +TP+ ++ + L+ AD++ Q NG TP+ +A LLLE A K+ LH A + +LE L N+ TP HL++
Sbjct: 10 DGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGA---------------------------IVDSATKK-----------GNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAV---AMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQ-----------KG----ADVNYSAKHNI-SPLHVAAKWGKTNMVSLLLE--KGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGL-APLHMAAQGEHVDAARILLY------HRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRI---LLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEV--AAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATA-KNGHTPLHIAARKNQMDIATTLLE----YGALANAESKAGFTPLHLSS 642 HSP 6 Score: 100.138 bits (248), Expect = 1.308e-20 Identity = 125/487 (25.67%), Postives = 205/487 (42.09%), Query Frame = 1
Query: 1840 HVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRT---SLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLI------NY----------VANKYHQGDFI----EKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEM--KSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEK---LPCLKKLINSLDNNQ---------QTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI 3189
H+ ++ + S + L+ +HLA+ GH +++ L++ IV + + G TALH+A+ G VK LL A ++ + Y A+Q + DA+ ++LS + D +PL +A+Q GH + L+ + DT G+ +LH A V+ LLLD + ++ G ++A+ G++N+ LI NY VA K+ + + + EK +I E K+ +D LTPLH AA GH ++ML E + K+ NG A D + A D + T + A H +V + L+ NAD N + +NG TP+ IA K+ L + LLL H A SA G+ L + C+ +I L ++ +TP HLAA + + L+ GA + + + Q P+
Sbjct: 30 HLKNNIDINTSNANGLNALHLASKDGHIHVVSELLR--RGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGF--TPLYMAAQENHDAVVRLLLSNGANQSLATEDGF-----TPLAVAMQQGHDKVVAVLLES-------DTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNI---EAKT----RDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVD---YLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLR-----------------HGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPL 473 HSP 7 Score: 75.8702 bits (185), Expect = 2.840e-13 Identity = 59/200 (29.50%), Postives = 97/200 (48.50%), Query Frame = 1
Query: 166 QTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIV--IRLIEKGAELDCVTTQG 759
T LH+AA +IA L++YG N++ G TPL + + +LI A N H+CA ++V+ +++ + I++ G T LH A G +V+ LL N ++ A+ G P+H A +G I+NLLL++ AN N + + T LHIA +G+I ++ ++ I K E +Q
Sbjct: 602 HTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQA 801
BLAST of Ankyrin repeat domain 28b vs. Ensembl Zebrafish
Match: ankrd28b (ankyrin repeat domain 28b [Source:ZFIN;Acc:ZDB-GENE-070622-4]) HSP 1 Score: 504.982 bits (1299), Expect = 5.352e-159 Identity = 353/1078 (32.75%), Postives = 547/1078 (50.74%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVL---SLIHLAAYHGHSEILNYLVQ-IFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKT 3291
P L +I D D +R ++ K DVN++D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + VL+ AD N RD W HV AA+ +V C + ++P + +N++D GRTALHHA +GH+E+V++LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI E N +N N +G LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I+ A+++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D+ +TPLH A N+ L+ GA+++ D+ C +HYAA + +G L L N AN I DN VH+A G+ L LE++ +E +D + +++S D + DVL S +HLAAYHGH + L LVQ + ++ + Q G T L LAA++GH V L++ GA D +H AA+ G + L +I + L+ S VD D ++PLM++V GHT LI GA+VD KD +GRT+LHR GH ECV+ LL +A + D RGR+ ++A++ GH +L L+ H +E + D TPLH+A GH C+E+L E K+ + LHCA+ + + +E +++ + ++N D + TP+ A D+V L+ L+ HNA +N D G TP+M+AA+ G + + +L+ L D + LH A ++ ++ILEK+ + LINS + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M SP ++ T
Sbjct: 10 PALLKAIFNVDPDEVRSLIFKKEDVNVQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDNKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHVAAANKAVRCAEALVPLLSNVNVSDRAGRTALHHAAFSGHLEMVRLLLSRGANINAFDKKDRRAIHWAAYMGHMEVVKLLVSHGAEVPCKDKKAYTPLHAAASSGMISVVKYLLDMGVDMNEPNAYGNTPLHVACYNGQDVVVNELI-----------------------ECGAN------------VNQVNEKGFAPLHFTAASRHGALCLELLVGNGADVNIKSKDGKTPLHMTAIHGRFSRSQAIIQNGAEIDCEDKNGNTPLHIAARYGHELLINTLITNGADTAKRGVHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNRKDSFGRTPLHYAAANCNYQCLFALVGSGANVNELDKRGCTPLHYAAASDADGKCLEYLLRNDAN---------------PGIRDNQGYNA-----VHYASAYGHR----LCLELIASETPLDVL---METSGTDILNDSDVLAPVSPLHLAAYHGHHQALEVLVQSLLDLDVRTAQ---GHTPLDLAAFKGHVECVDVLINQGASILVKDYTLKRTPIHAAATNGHSECLRLLIGNADLQ---SAVDIQDGIGQTPLMLSVLGGHTDCVYSLINKGANVDAKDKWGRTALHRGAVTGHEECVEALLQHSASFMVRDCRGRSPVHLASACGHVGVLGGLL-------HAAQSVES---------IPVITDHQGYTPLHWACYNGHDTCVEVLLEQELFHKTEGNPFSPLHCAVINDNEGAVELLIETLSPVIVNANDSKNRTPLHAAAFTDHVECLQLLLGHNAQVNCVDAGGKTPLMMAAENGQTNAVEVLVSSAKADLTLQDANKNTALHLACSKGHETSALLILEKI-TDRNLINSTNAALQTPLHVAARNGLTVVVQELLAKGASVLAVDENGYTPALACAPNKDVADCLALILATMMPV--SPGGGSVPT 995 HSP 2 Score: 151.754 bits (382), Expect = 1.405e-36 Identity = 211/908 (23.24%), Postives = 382/908 (42.07%), Query Frame = 1
Query: 940 LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPININDH-------LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRS--GRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRK---------------------------SLVDSLDEHKRSPL-MIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRN------------AFYMAASAGHKNLLMKLINYVAN---KYHQG----DFIE-KSH----DIFINELKSMWFDQDYL---TPLHFAASRGHTNCIEMLYELSD-----EMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLEC-QTLKW--ALVDKSNQNILHYAGQSADDSCGIIILEK-------------LPCL-----------------KKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALK-----TSLNLSPKKGY 3321
+N ++ + T LH + + +A + ++LL+ GA N +PLH A + + +L+K ADVN +D + TPLH+A + + L+ +N V+ G +H A AF M +LL ++ +IN D R +H A G ++ ++ ++ G ++ +D TPLH A + + L+ +G ++ + Y +H A YN + ++ L + GAN+ +P++ L + N D K P+H + G F +++ N A++DC D + N + +H+AA +GH ++N L+ N T R G LHLAA G + + LLS G D D+ LH AA+ G+++ LN ++ + NRK + V+ LD+ +PL A + + E L+ N A+ ++D G ++H A+A GH C++L+ L + G + ++AA GH L L+ + + + QG D K H D+ IN+ S+ +DY TP+H AA+ GH+ C+ +L +D +++ G + + D + K AN ++ DK+ T + + +E L+ H+A +D G +P+ +A+ G + L LL Q+++ + D LH+A + D+C ++LE+ L C ++N+ D+ +TP H AAF L L+ A + + + P++ N + ++ +E+ +++ + A+L L+ T+L+L+ KG+
Sbjct: 34 VNVQDNEKRTPLHAAAYLGDA-EIIELLILSGARVNAKDNKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHVAAANKAVRCAEALVPLLSNVNVSDRAGRTALHHA-AFSGHLEMVRLL--LSRGANINAFDKKD--RRAIHWAAYMGHMEVVKLLVSHGAEVPCKDKKAYTPLHAAASSGMISVVKYLLDMGVDMNEPNAYGNTPLHVAC-YNGQDVVVNELIECGANVNQVNEKGFAPLHFTAASRHGALCLELLVGNGADVNIKSKDGKTPLHMTAIHGRFSRSQAIIQ---NGAEIDC----EDKNGN---------TPLHIAARYGHELLINTLI----TNGADTAKRGVHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPD-DFGRTCLHAAAAGGNLECLNLLLNTGADFNRKDSFGRTPLHYAAANCNYQCLFALVGSGANVNELDKRGCTPLHYAAASDADGKCLEYLLRNDANPGIRDNQGYNAVHYASAYGHRLCLELIASETPLDVLMETSGTDILNDSDVLAPVSPLHLAAYHGHHQALEVLVQSLLDLDVRTAQGHTPLDLAAFKGHVECVDVLINQGASILV-KDYTLKRTPIHAAATNGHSECLRLLIGNADLQSAVDIQDGIGQTPLMLSVLGGHTDCVYSLINKGAN---VDAKDKWGRTALHRGAVTGHEECVEALLQHSASFMVRDCRGRSPVHLASACGHVGVLGGLLHAAQSVESIPVITDHQGYTPLHWACYNGHDTCVEVLLEQELFHKTEGNPFSPLHCAVINDNEGAVELLIETLSPVIVNANDSKNRTPLHAAAFTDHVECLQLLLGHNAQVNCVDAGGKTPLMMAAENGQ-TNAVEVLVSS------AKADLTLQDANKNTALHLACSKGH 902
BLAST of Ankyrin repeat domain 28b vs. Ensembl Zebrafish
Match: ankrd28b (ankyrin repeat domain 28b [Source:ZFIN;Acc:ZDB-GENE-070622-4]) HSP 1 Score: 504.982 bits (1299), Expect = 5.352e-159 Identity = 353/1078 (32.75%), Postives = 547/1078 (50.74%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVL---SLIHLAAYHGHSEILNYLVQ-IFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKT 3291
P L +I D D +R ++ K DVN++D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + VL+ AD N RD W HV AA+ +V C + ++P + +N++D GRTALHHA +GH+E+V++LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI E N +N N +G LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I+ A+++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D+ +TPLH A N+ L+ GA+++ D+ C +HYAA + +G L L N AN I DN VH+A G+ L LE++ +E +D + +++S D + DVL S +HLAAYHGH + L LVQ + ++ + Q G T L LAA++GH V L++ GA D +H AA+ G + L +I + L+ S VD D ++PLM++V GHT LI GA+VD KD +GRT+LHR GH ECV+ LL +A + D RGR+ ++A++ GH +L L+ H +E + D TPLH+A GH C+E+L E K+ + LHCA+ + + +E +++ + ++N D + TP+ A D+V L+ L+ HNA +N D G TP+M+AA+ G + + +L+ L D + LH A ++ ++ILEK+ + LINS + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M SP ++ T
Sbjct: 10 PALLKAIFNVDPDEVRSLIFKKEDVNVQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDNKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHVAAANKAVRCAEALVPLLSNVNVSDRAGRTALHHAAFSGHLEMVRLLLSRGANINAFDKKDRRAIHWAAYMGHMEVVKLLVSHGAEVPCKDKKAYTPLHAAASSGMISVVKYLLDMGVDMNEPNAYGNTPLHVACYNGQDVVVNELI-----------------------ECGAN------------VNQVNEKGFAPLHFTAASRHGALCLELLVGNGADVNIKSKDGKTPLHMTAIHGRFSRSQAIIQNGAEIDCEDKNGNTPLHIAARYGHELLINTLITNGADTAKRGVHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNRKDSFGRTPLHYAAANCNYQCLFALVGSGANVNELDKRGCTPLHYAAASDADGKCLEYLLRNDAN---------------PGIRDNQGYNA-----VHYASAYGHR----LCLELIASETPLDVL---METSGTDILNDSDVLAPVSPLHLAAYHGHHQALEVLVQSLLDLDVRTAQ---GHTPLDLAAFKGHVECVDVLINQGASILVKDYTLKRTPIHAAATNGHSECLRLLIGNADLQ---SAVDIQDGIGQTPLMLSVLGGHTDCVYSLINKGANVDAKDKWGRTALHRGAVTGHEECVEALLQHSASFMVRDCRGRSPVHLASACGHVGVLGGLL-------HAAQSVES---------IPVITDHQGYTPLHWACYNGHDTCVEVLLEQELFHKTEGNPFSPLHCAVINDNEGAVELLIETLSPVIVNANDSKNRTPLHAAAFTDHVECLQLLLGHNAQVNCVDAGGKTPLMMAAENGQTNAVEVLVSSAKADLTLQDANKNTALHLACSKGHETSALLILEKI-TDRNLINSTNAALQTPLHVAARNGLTVVVQELLAKGASVLAVDENGYTPALACAPNKDVADCLALILATMMPV--SPGGGSVPT 995 HSP 2 Score: 151.754 bits (382), Expect = 1.405e-36 Identity = 211/908 (23.24%), Postives = 382/908 (42.07%), Query Frame = 1
Query: 940 LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPININDH-------LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRS--GRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRK---------------------------SLVDSLDEHKRSPL-MIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRN------------AFYMAASAGHKNLLMKLINYVAN---KYHQG----DFIE-KSH----DIFINELKSMWFDQDYL---TPLHFAASRGHTNCIEMLYELSD-----EMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLEC-QTLKW--ALVDKSNQNILHYAGQSADDSCGIIILEK-------------LPCL-----------------KKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALK-----TSLNLSPKKGY 3321
+N ++ + T LH + + +A + ++LL+ GA N +PLH A + + +L+K ADVN +D + TPLH+A + + L+ +N V+ G +H A AF M +LL ++ +IN D R +H A G ++ ++ ++ G ++ +D TPLH A + + L+ +G ++ + Y +H A YN + ++ L + GAN+ +P++ L + N D K P+H + G F +++ N A++DC D + N + +H+AA +GH ++N L+ N T R G LHLAA G + + LLS G D D+ LH AA+ G+++ LN ++ + NRK + V+ LD+ +PL A + + E L+ N A+ ++D G ++H A+A GH C++L+ L + G + ++AA GH L L+ + + + QG D K H D+ IN+ S+ +DY TP+H AA+ GH+ C+ +L +D +++ G + + D + K AN ++ DK+ T + + +E L+ H+A +D G +P+ +A+ G + L LL Q+++ + D LH+A + D+C ++LE+ L C ++N+ D+ +TP H AAF L L+ A + + + P++ N + ++ +E+ +++ + A+L L+ T+L+L+ KG+
Sbjct: 34 VNVQDNEKRTPLHAAAYLGDA-EIIELLILSGARVNAKDNKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHVAAANKAVRCAEALVPLLSNVNVSDRAGRTALHHA-AFSGHLEMVRLL--LSRGANINAFDKKD--RRAIHWAAYMGHMEVVKLLVSHGAEVPCKDKKAYTPLHAAASSGMISVVKYLLDMGVDMNEPNAYGNTPLHVAC-YNGQDVVVNELIECGANVNQVNEKGFAPLHFTAASRHGALCLELLVGNGADVNIKSKDGKTPLHMTAIHGRFSRSQAIIQ---NGAEIDC----EDKNGN---------TPLHIAARYGHELLINTLI----TNGADTAKRGVHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPD-DFGRTCLHAAAAGGNLECLNLLLNTGADFNRKDSFGRTPLHYAAANCNYQCLFALVGSGANVNELDKRGCTPLHYAAASDADGKCLEYLLRNDANPGIRDNQGYNAVHYASAYGHRLCLELIASETPLDVLMETSGTDILNDSDVLAPVSPLHLAAYHGHHQALEVLVQSLLDLDVRTAQGHTPLDLAAFKGHVECVDVLINQGASILV-KDYTLKRTPIHAAATNGHSECLRLLIGNADLQSAVDIQDGIGQTPLMLSVLGGHTDCVYSLINKGAN---VDAKDKWGRTALHRGAVTGHEECVEALLQHSASFMVRDCRGRSPVHLASACGHVGVLGGLLHAAQSVESIPVITDHQGYTPLHWACYNGHDTCVEVLLEQELFHKTEGNPFSPLHCAVINDNEGAVELLIETLSPVIVNANDSKNRTPLHAAAFTDHVECLQLLLGHNAQVNCVDAGGKTPLMMAAENGQ-TNAVEVLVSS------AKADLTLQDANKNTALHLACSKGH 902
BLAST of Ankyrin repeat domain 28b vs. Ensembl Zebrafish
Match: ankrd52a (ankyrin repeat domain 52a [Source:NCBI gene;Acc:553206]) HSP 1 Score: 487.649 bits (1254), Expect = 2.459e-152 Identity = 342/1089 (31.40%), Postives = 544/1089 (49.95%), Query Frame = 1
Query: 52 MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELI-KALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTL--------KTHINNLD-----DDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFI-ENNIMDNTS----LGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSD-EMKSTNGFMTFLHCAIDSKCDETLECVLKIA-NNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKL--PCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAM 3249
+N + P L +I ++D ++ L+ K +VN D +T LH AA++G+ +I D+LI G +VN+KD +TPL +A AS + + +L+ GAD RD W H+ AA+ + C++ +LPHV +N+ D GR LHHA +G+ E+VK+LL+ ++SASDK +PIHWAA G LE++ LL+ ++ + +DK YT LH A+A GH+D+V L+ GAE+D GN ALH+A + EL+ + N +N N++G T LH+ + N C++LL+ GA+ N+ S+ GKSPLH AA + ++ +LI+ +++ D + NTPLH+A ++G+E + L+ A+ G GM P+H+A + + C KLL + L K H+ + D GR +H A +GG+++CL ++ G D++ +D +TPLH A + +L+ GA ++ D C +HY+A R N + SF+ +++DN + K VH+A GN + LLLEM N + D +S + S +HLA GH E + L++ S V D GR+ L+LA+ +GH+ V+ LLS A + W LH AA+ G + L ++ S E LV+ D ++PLM+AV GHT L+ GA D+KD GRT+LHR G +C+ LL N + DF+GR+A ++AAS GH ++L L++ + Q D+ TP H+AA GH +C+E+L EL ++ N F T LHCA+ + + E +L+ + N L+N D TP+ A ++V L+ ++ ADI+ D +G + +M+AA G + LLL +L+D + LH A A + C ++IL+++ P LIN+ ++ Q P H+AA N L + AL+ GA + + + P ++C N +DC+ + L+ M
Sbjct: 4 LNISDQPPLVQAIFNRNADEVKLFLHKKDEVNALDQERRTPLHAAAWLGDVHIMDLLISAGANVNAKDHVWLTPLHRAAASRNERAVGLLLRKGADVTARDKYWQTPLHIAAANRATRCVETLLPHVSSLNMADRTGRAPLHHAAQSGYQEMVKLLLNKGANLSASDKKDRQPIHWAAYLGHLEVVKLLVSQGSDKSCKDKRGYTPLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYTGQEAVANELVNRGAN------------------------------------VNQPNHRGYTPLHLAAVSTNGALCLELLVNNGADVNMQSKEGKSPLHMAAIHGRFTRSQILIQNGGEIDCVDRYGNTPLHVAAKYGHELLISTLMTNGADTARQGIHGMFPLHLAVLYGSSDCCRKLLSSGQLYSIVLSMSKEHVLSAGFDINTPDNFGRTCLHAAASGGNIECLNLLLSSGADMNKKDKFGRTPLHYAAANGRYQCVVVLVGAGAEVNERDRSGCTPLHYSAASTAFCRTDRPHASTHQN----QEDGEKESFLCVEHLLDNGADPCLCNTKGYSAVHYAAAHGNKQNLELLLEMCFN-------------TLGDKESNGSI-SPLHLAVESGHWECVTVLIE--SGACVDVCDPVGRSVLYLASQRGHSRCVELLLSQSASCLLAEHRSKWGPLHVAAANGHSECLRMLLCS---EGGADLVNVTDAEGQTPLMLAVLGGHTDCVHLLLERGACPDMKDRRGRTALHRGAVMGREDCLTALLSHNVSVLSRDFQGRSALHLAASCGHADILSNLLSAADHSQPQDPLT----------------DRHGYTPAHWAAYHGHEDCLEVLLELKPCSIQEGNPF-TPLHCALINGHSGSAELLLESSVCNSLVNIRDAKGRTPLHAAAVAEDVAGLQLVLRQGADIDAVDHSGRSALMVAADYGQSGAVALLLHRAKADLSLLDVNKNTALHLACSKAHEMCAMLILKEIHNPI---LINATNSMLQMPLHIAARNGLATVVQALLNRGATVLAVDEEGHTPALACASNKAVADCLALILSTM 1013
BLAST of Ankyrin repeat domain 28b vs. Ensembl Zebrafish
Match: ankrd52a (ankyrin repeat domain 52a [Source:NCBI gene;Acc:553206]) HSP 1 Score: 466.848 bits (1200), Expect = 1.272e-144 Identity = 333/1078 (30.89%), Postives = 535/1078 (49.63%), Query Frame = 1
Query: 52 MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELI-KALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKAN--AFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFI-ENNIMDNTS----LGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSD-EMKSTNGFMTFLHCAIDSKCDETLECVLKIA-NNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKL--PCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAM 3249
+N + P L +I ++D ++ L+ K +VN D +T LH AA++G+ +I D+LI G +VN+KD +TPL +A AS + + +L+ GAD RD W H+ AA+ + C++ +LPHV +N+ D GR LHHA +G+ E+VK+LL+ ++SASDK +PIHWAA G LE++ LL+ ++ + +DK YT LH A+A GH+D+V L+ GAE+D GN ALH+A + EL+ + N +N N++G T LH+ + N C++LL+ GA+ N+ S+ GKSPLH AA + ++ +LI+ +++ D + NTPLH+A ++G+E + L+ A+ +F + ++ + + M K L + D GR +H A +GG+++CL ++ G D++ +D +TPLH A + +L+ GA ++ D C +HY+A R N + SF+ +++DN + K VH+A GN + LLLEM N + D +S + S +HLA GH E + L++ S V D GR+ L+LA+ +GH+ V+ LLS A + W LH AA+ G + L ++ S E LV+ D ++PLM+AV GHT L+ GA D+KD GRT+LHR G +C+ LL N + DF+GR+A ++AAS GH ++L L++ + Q D+ TP H+AA GH +C+E+L EL ++ N F T LHCA+ + + E +L+ + N L+N D TP+ A ++V L+ ++ ADI+ D +G + +M+AA G + LLL +L+D + LH A A + C ++IL+++ P LIN+ ++ Q P H+AA N L + AL+ GA + + + P ++C N +DC+ + L+ M
Sbjct: 4 LNISDQPPLVQAIFNRNADEVKLFLHKKDEVNALDQERRTPLHAAAWLGDVHIMDLLISAGANVNAKDHVWLTPLHRAAASRNERAVGLLLRKGADVTARDKYWQTPLHIAAANRATRCVETLLPHVSSLNMADRTGRAPLHHAAQSGYQEMVKLLLNKGANLSASDKKDRQPIHWAAYLGHLEVVKLLVSQGSDKSCKDKRGYTPLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYTGQEAVANELVNRGAN------------------------------------VNQPNHRGYTPLHLAAVSTNGALCLELLVNNGADVNMQSKEGKSPLHMAAIHGRFTRSQILIQNGGEIDCVDRYGNTPLHVAAKYGHELLISTLMTNGADTASFETSDKQIVCVFAGQLYSIVLSMSK---EHVLSAGFDINTPDNFGRTCLHAAASGGNIECLNLLLSSGADMNKKDKFGRTPLHYAAANGRYQCVVVLVGAGAEVNERDRSGCTPLHYSAASTAFCRTDRPHASTHQN----QEDGEKESFLCVEHLLDNGADPCLCNTKGYSAVHYAAAHGNKQNLELLLEMCFN-------------TLGDKESNGSI-SPLHLAVESGHWECVTVLIE--SGACVDVCDPVGRSVLYLASQRGHSRCVELLLSQSASCLLAEHRSKWGPLHVAAANGHSECLRMLLCS---EGGADLVNVTDAEGQTPLMLAVLGGHTDCVHLLLERGACPDMKDRRGRTALHRGAVMGREDCLTALLSHNVSVLSRDFQGRSALHLAASCGHADILSNLLSAADHSQPQDPLT----------------DRHGYTPAHWAAYHGHEDCLEVLLELKPCSIQEGNPF-TPLHCALINGHSGSAELLLESSVCNSLVNIRDAKGRTPLHAAAVAEDVAGLQLVLRQGADIDAVDHSGRSALMVAADYGQSGAVALLLHRAKADLSLLDVNKNTALHLACSKAHEMCAMLILKEIHNPI---LINATNSMLQMPLHIAARNGLATVVQALLNRGATVLAVDEEGHTPALACASNKAVADCLALILSTM 999 HSP 2 Score: 142.51 bits (358), Expect = 8.304e-34 Identity = 184/784 (23.47%), Postives = 319/784 (40.69%), Query Frame = 1
Query: 1066 KSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMD-------------CIKGH-------VDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGH------TRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAAS--------RGHTN--------------CIEMLYELSDE--MKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVD-KSNQNILHYAGQSADDSCGIIILEKLPCLKK---LINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFS 3255
+ PL A + L + K +VN D TPLH A G + +L+ AN + P+H A A +N + + L+ + D + +H A A + +C+ET++ ++ D + PLH A + + ++L+ GA++ D+ IH+AA Y ++++LL G+ D + K+ P+H A SG+ D + LL N A++D C G V+ N Q + +HLAA + + L+ + + V+ Q + G++ LH+AA G + L+ G + VD+ Y LH AA G +E+++S + N D+ ++ V G + + E ++ G D++ D +GRT LH A + G++EC++LLL A + D GR + AA+ G ++ L+ A +NE D+ TPLH++A+ R H + C+E L + + + +T G+ + +H A + LE +L++ N L + S +P+ AV + + LI A ++ D G + + +A++ G C+ LLL Q+ L + +S LH A + C L L C + L+N D QTP LA ++ L+ GA +K+ + + + + A E CL A+ S
Sbjct: 9 QPPLVQAIFNRNADEVKLFLHKKDEVNALDQERRTPLHAAAWLGDVHIMDLLISAGANVNAKDHVWLTPLHRAAASRN-----ERAVGLLLRKGADVTARDKYWQTPLHIAAANRATRCVETLLPHVSSLNMADRTGRAPLHHAAQSGYQEMVKLLLNKGANLSASDKKDRQPIHWAA-YLGHLEVVKLLVSQGS--------------------DKSCKDKRGYTPLHAAAASGHVDVVKYLLR---NGAEIDEPNAFGNTALHVACYTGQEAVANELVNRGANVNQPNHRGYTPLHLAAVSTNGALCLELL-VNNGADVNMQSKEGKSPLHMAAIHGRFTRSQILIQNGGEIDCVDR-YGNTPLHVAAKYG-----HELLISTLMTNG---ADTASFETSDKQIVCVFAGQLYSIVLSMSKEHVLSAGFDINTPDNFGRTCLHAAASGGNIECLNLLLSSGADMNKKDKFGRTPLHYAAANGRYQCVVVLVGAGAE---------------VNE-----RDRSGCTPLHYSAASTAFCRTDRPHASTHQNQEDGEKESFLCVEHLLDNGADPCLCNTKGY-SAVHYAAAHGNKQNLELLLEMCFNTLGDKESNGSISPLHLAVESGHWECVTVLIESGACVDVCDPVGRSVLYLASQRGHSRCVELLLS-QSASCLLAEHRSKWGPLHVAAANGHSEC----LRMLLCSEGGADLVNVTDAEGQTPLMLAVLGGHTDCVHLLLERGACPDMKDRRGRTAL-----HRGAVMGREDCLTALLS 722
BLAST of Ankyrin repeat domain 28b vs. Ensembl Zebrafish
Match: ankrd44 (ankyrin repeat domain 44 [Source:ZFIN;Acc:ZDB-GENE-070912-605]) HSP 1 Score: 454.521 bits (1168), Expect = 2.746e-140 Identity = 339/1120 (30.27%), Postives = 527/1120 (47.05%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDN---------------VTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVY-PVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAM--FSSTDSPANLALKTSLNLSPKKGYVINLKEAELEGSIQSSEN 3375
P L +I D D +R L DVN DA + LH AA++G++ I ++LI G VN+KD +TPL +A AS S + VLI AD N RD W HV AA+ ++ C ++I+P + +N++D GRTALHHA NGH E+V +LL +I+A DK R +HWAA G L+++ LL+ A ++ +DK YT LH A++ G I +V L+ E+D GN ALH+A N +V ELI +N Q N +G T LH + + C++ L+ GA+ N+ S +GKSPLH A + ++ LI+ +++ D NTPLH+A R+G+E + L+ A+ G GM P+H+A + C KLL + ++ I+ DD LGR +H A AGG+++C++ ++ G D + D +TPLH A +F L+ G I+ D++ A+HYAA + + L L +GA SL K Y VH+A G+ + LLL+ D + D + S +HLAAYHGH++ L L++ + V D RT L LAA +GH LL+ GA P + D +H A G + L ++ + LVD+ D ++PLM+AV GH L+ A VD+ D +G T LH G ECV LL+ A + L D RGR A ++AA+ GH + L +L++ IE L + +Q Y TPLH+A GH C+E++ + D + T LHCA+ + + +L+ + ++ D TP A +V+ ++ L+ HNA +N D +G + + +AA++G + + LL + L+D+ LH A + + C +++L KLP + + ++ QTP HLAA + + + L++ GA + + + P ++C + + +DC+ + LA M F S S + T L P + + + S SSE
Sbjct: 1 PPLVQAIFNGDPDEIRVLLCKSEDVNALDAEKRAPLHAAAFLGDAEITELLIVSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLAKGANINAFDKKDCRALHWAAYMGHLDVVCLLVSQGAEISCKDKRGYTPLHAAASNGQIAVVKHLLSLAVEIDEANAFGNTALHVACFNGQDAVVSELID-----------YGANVSQP------------------------NNKGFTPLHFAAASTHGALCLEFLVNSGADVNVQSRDGKSPLHLTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADCTRRGVHGMFPLHLAALNAHADCCRKLLSSGRRYSIMCPLSNDSVLSAGFQIDTPDD--LGRTCLHAAAAGGNVECVKLLLSSGADHNRRDKHGRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRTAVHYAAASDLDRRCLEFLLQHGA---------------------GPSLKDKQGYSAVHYAAAYGHRHCLKLLLDR--------------DENHQDDMENNQTRSPLHLAAYHGHAQALEVLLEGHCE--VDQGDEVDRTPLALAALRGHTDCALTLLNHGASPRSRDTVRGRTPIHLAVMNGHTSCVR---LLLEDSDNADLVDTADSQGQTPLMLAVMGGHVDAVSLLLERDASVDMADHHGLTGLHLGLLCGQEECVQSLLELEASVLLGDSRGRTAIHLAAARGHASWLSELLSIAC--------IEPP-------LPPLRDNQGY-TPLHYACYYGHEGCVEVILDQKDFCQFEGNPFTPLHCAVVNDHETCATLLLEAMGSKIVTCKDSKGRTPFHAAAFAGHVDCVQLLLSHNASVNEVDQSGRSALCMAAEKGRVEVVEALLAAADVNINLIDQKGNTALHLACSNGMEECALLLLGKLP--DSALVATNSALQTPLHLAARSGMKQTVQELLSRGASVQVLDENGLTPALACAPSREVADCLALILATMMPFCSPCSSGAPSPGTLLKSLPHQAKSPQGPRSPKDPSGPSSEG 1025
BLAST of Ankyrin repeat domain 28b vs. Ensembl Xenopus
Match: rev1 (REV1, DNA directed polymerase [Source:Xenbase;Acc:XB-GENE-968197]) HSP 1 Score: 519.62 bits (1337), Expect = 2.197e-164 Identity = 344/1061 (32.42%), Postives = 540/1061 (50.90%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVA--TAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQ-NDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLA 3243
P L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH+E+V +LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I ++ L++ G +++ GN LH+A N +V ELI + +N N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ ++I+ A+++ +D + NTPLHIA R+G+E + L+ +A+ G GM P+H+A + F +C C L + TH D GR +H A AGG+L+CL ++ G D + +D +TPLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K VH+A G+ L LE++ E +D + + ND +++ + S +HLAAYHGH + L LVQ + ++ +GRT L LAA++GH V L++ GA D +H AA G + L +I + ++ + VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECV+ LL NA L D RGR ++AA+ GH +L L+ I ++ + ++ + Y TPLH+A GH C+E+L E K + LHCA+ + + E ++ ++N+ D TP+ A D++ L+ L+ HNA +N D G TP+M+AA+ G S + +L+ L DK+ LH A ++ ++ILE++ + LIN+ ++ QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA
Sbjct: 10 PPLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEDAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHVEMVSLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVTHGAEVMCKDKKSYTPLHAAASSGMISVIKYLLDLGVDMNESNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GANVNQVNERGFTPLHFAAASTHGALCLELLVCNGADVNIKSKDGKTPLHMTAIHGRFSRSQIIIQNGAEIDCEDKNGNTPLHIAARYGHELLINTLITSRADTSKRGIHGMFPLHLAALSGFSDC-CRKLLSSGFDIDTH------DDFGRTCLHAAAAGGNLECLNLLLSTGADFNKKDKFGRTPLHYAAANCNYQCLFALVGSGASVNDLDERGCSPLHYAATSDTDGKCLEYLLRNDANP----GIRD----------------KHGYNAVHYAAAYGHR----LCLELIARETPLDVLMETSGTDMLNDAETRAPI-SPLHLAAYHGHHQALEVLVQSLLD--LDVRNSTGRTPLDLAAFKGHVECVDVLINQGASILVKDYVVKRTPIHSAAINGHSECLRLLIGNADVQ---AAVDIHDGNGQTPLMLSVLNGHTECVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVEALLQHNANFLLRDCRGRTPIHLAAACGHIGVLSALLQTA---------------ISVDVVPAIADNHGY-TPLHWACYNGHDACVELLLEQEVFQKMEGNSFSPLHCAVINDNEGAAEMLIDTLGTSIVNSVDSKGRTPLHAAAFTDHIECLQLLLSHNAQVNAVDSTGKTPLMMAAENGQTSAVEVLVSSAKADLTLQDKNKNTALHLACSKGHETSALLILEQI-TDRNLINATNSALQTPLHVAARNGLTVVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILA 981
BLAST of Ankyrin repeat domain 28b vs. Ensembl Xenopus
Match: rev1 (REV1, DNA directed polymerase [Source:Xenbase;Acc:XB-GENE-968197]) HSP 1 Score: 520.39 bits (1339), Expect = 2.652e-164 Identity = 344/1063 (32.36%), Postives = 541/1063 (50.89%), Query Frame = 1
Query: 64 IIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVA--TAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQ-NDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLA 3243
+ P L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH+E+V +LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I ++ L++ G +++ GN LH+A N +V ELI + +N N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ ++I+ A+++ +D + NTPLHIA R+G+E + L+ +A+ G GM P+H+A + F +C C L + TH D GR +H A AGG+L+CL ++ G D + +D +TPLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K VH+A G+ L LE++ E +D + + ND +++ + S +HLAAYHGH + L LVQ + ++ +GRT L LAA++GH V L++ GA D +H AA G + L +I + ++ + VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECV+ LL NA L D RGR ++AA+ GH +L L+ I ++ + ++ + Y TPLH+A GH C+E+L E K + LHCA+ + + E ++ ++N+ D TP+ A D++ L+ L+ HNA +N D G TP+M+AA+ G S + +L+ L DK+ LH A ++ ++ILE++ + LIN+ ++ QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA
Sbjct: 35 VTPPLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEDAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHVEMVSLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVTHGAEVMCKDKKSYTPLHAAASSGMISVIKYLLDLGVDMNESNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GANVNQVNERGFTPLHFAAASTHGALCLELLVCNGADVNIKSKDGKTPLHMTAIHGRFSRSQIIIQNGAEIDCEDKNGNTPLHIAARYGHELLINTLITSRADTSKRGIHGMFPLHLAALSGFSDC-CRKLLSSGFDIDTH------DDFGRTCLHAAAAGGNLECLNLLLSTGADFNKKDKFGRTPLHYAAANCNYQCLFALVGSGASVNDLDERGCSPLHYAATSDTDGKCLEYLLRNDANP----GIRD----------------KHGYNAVHYAAAYGHR----LCLELIARETPLDVLMETSGTDMLNDAETRAPI-SPLHLAAYHGHHQALEVLVQSLLD--LDVRNSTGRTPLDLAAFKGHVECVDVLINQGASILVKDYVVKRTPIHSAAINGHSECLRLLIGNADVQ---AAVDIHDGNGQTPLMLSVLNGHTECVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVEALLQHNANFLLRDCRGRTPIHLAAACGHIGVLSALLQTA---------------ISVDVVPAIADNHGY-TPLHWACYNGHDACVELLLEQEVFQKMEGNSFSPLHCAVINDNEGAAEMLIDTLGTSIVNSVDSKGRTPLHAAAFTDHIECLQLLLSHNAQVNAVDSTGKTPLMMAAENGQTSAVEVLVSSAKADLTLQDKNKNTALHLACSKGHETSALLILEQI-TDRNLINATNSALQTPLHVAARNGLTVVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILA 1008
BLAST of Ankyrin repeat domain 28b vs. Ensembl Xenopus
Match: rev1 (REV1, DNA directed polymerase [Source:Xenbase;Acc:XB-GENE-968197]) HSP 1 Score: 519.235 bits (1336), Expect = 3.103e-164 Identity = 344/1061 (32.42%), Postives = 540/1061 (50.90%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVA--TAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQ-NDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLA 3243
P L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH+E+V +LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I ++ L++ G +++ GN LH+A N +V ELI + +N N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ ++I+ A+++ +D + NTPLHIA R+G+E + L+ +A+ G GM P+H+A + F +C C L + TH D GR +H A AGG+L+CL ++ G D + +D +TPLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K VH+A G+ L LE++ E +D + + ND +++ + S +HLAAYHGH + L LVQ + ++ +GRT L LAA++GH V L++ GA D +H AA G + L +I + ++ + VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECV+ LL NA L D RGR ++AA+ GH +L L+ I ++ + ++ + Y TPLH+A GH C+E+L E K + LHCA+ + + E ++ ++N+ D TP+ A D++ L+ L+ HNA +N D G TP+M+AA+ G S + +L+ L DK+ LH A ++ ++ILE++ + LIN+ ++ QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA
Sbjct: 10 PPLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEDAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHVEMVSLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVTHGAEVMCKDKKSYTPLHAAASSGMISVIKYLLDLGVDMNESNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GANVNQVNERGFTPLHFAAASTHGALCLELLVCNGADVNIKSKDGKTPLHMTAIHGRFSRSQIIIQNGAEIDCEDKNGNTPLHIAARYGHELLINTLITSRADTSKRGIHGMFPLHLAALSGFSDC-CRKLLSSGFDIDTH------DDFGRTCLHAAAAGGNLECLNLLLSTGADFNKKDKFGRTPLHYAAANCNYQCLFALVGSGASVNDLDERGCSPLHYAATSDTDGKCLEYLLRNDANP----GIRD----------------KHGYNAVHYAAAYGHR----LCLELIARETPLDVLMETSGTDMLNDAETRAPI-SPLHLAAYHGHHQALEVLVQSLLD--LDVRNSTGRTPLDLAAFKGHVECVDVLINQGASILVKDYVVKRTPIHSAAINGHSECLRLLIGNADVQ---AAVDIHDGNGQTPLMLSVLNGHTECVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVEALLQHNANFLLRDCRGRTPIHLAAACGHIGVLSALLQTA---------------ISVDVVPAIADNHGY-TPLHWACYNGHDACVELLLEQEVFQKMEGNSFSPLHCAVINDNEGAAEMLIDTLGTSIVNSVDSKGRTPLHAAAFTDHIECLQLLLSHNAQVNAVDSTGKTPLMMAAENGQTSAVEVLVSSAKADLTLQDKNKNTALHLACSKGHETSALLILEQIT-DRNLINATNSALQTPLHVAARNGLTVVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILA 981
BLAST of Ankyrin repeat domain 28b vs. Ensembl Xenopus
Match: rev1 (REV1, DNA directed polymerase [Source:Xenbase;Acc:XB-GENE-968197]) HSP 1 Score: 518.079 bits (1333), Expect = 1.321e-163 Identity = 344/1061 (32.42%), Postives = 540/1061 (50.90%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVA--TAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQ-NDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLA 3243
P L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH+E+V +LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I ++ L++ G +++ GN LH+A N +V ELI + +N N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ ++I+ A+++ +D + NTPLHIA R+G+E + L+ +A+ G GM P+H+A + F +C C L + TH D GR +H A AGG+L+CL ++ G D + +D +TPLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K VH+A G+ L LE++ E +D + + ND +++ + S +HLAAYHGH + L LVQ + ++ +GRT L LAA++GH V L++ GA D +H AA G + L +I + ++ + VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECV+ LL NA L D RGR ++AA+ GH +L L+ I ++ + ++ + Y TPLH+A GH C+E+L E K + LHCA+ + + E ++ ++N+ D TP+ A D++ L+ L+ HNA +N D G TP+M+AA+ G S + +L+ L DK+ LH A ++ ++ILE++ + LIN+ ++ QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA
Sbjct: 29 PPLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEDAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHVEMVSLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVTHGAEVMCKDKKSYTPLHAAASSGMISVIKYLLDLGVDMNESNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GANVNQVNERGFTPLHFAAASTHGALCLELLVCNGADVNIKSKDGKTPLHMTAIHGRFSRSQIIIQNGAEIDCEDKNGNTPLHIAARYGHELLINTLITSRADTSKRGIHGMFPLHLAALSGFSDC-CRKLLSSGFDIDTH------DDFGRTCLHAAAAGGNLECLNLLLSTGADFNKKDKFGRTPLHYAAANCNYQCLFALVGSGASVNDLDERGCSPLHYAATSDTDGKCLEYLLRNDANP----GIRD----------------KHGYNAVHYAAAYGHR----LCLELIARETPLDVLMETSGTDMLNDAETRAPI-SPLHLAAYHGHHQALEVLVQSLLD--LDVRNSTGRTPLDLAAFKGHVECVDVLINQGASILVKDYVVKRTPIHSAAINGHSECLRLLIGNADVQ---AAVDIHDGNGQTPLMLSVLNGHTECVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVEALLQHNANFLLRDCRGRTPIHLAAACGHIGVLSALLQTA---------------ISVDVVPAIADNHGY-TPLHWACYNGHDACVELLLEQEVFQKMEGNSFSPLHCAVINDNEGAAEMLIDTLGTSIVNSVDSKGRTPLHAAAFTDHIECLQLLLSHNAQVNAVDSTGKTPLMMAAENGQTSAVEVLVSSAKADLTLQDKNKNTALHLACSKGHETSALLILEQIT-DRNLINATNSALQTPLHVAARNGLTVVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILA 1000
BLAST of Ankyrin repeat domain 28b vs. Ensembl Xenopus
Match: rev1 (REV1, DNA directed polymerase [Source:Xenbase;Acc:XB-GENE-968197]) HSP 1 Score: 506.523 bits (1303), Expect = 1.841e-159 Identity = 339/1065 (31.83%), Postives = 540/1065 (50.70%), Query Frame = 1
Query: 67 IPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVA--TAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDH----LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLA 3243
+P L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH+E+V +LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I ++ L++ G +++ GN LH+A N +V ELI + +N N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ ++I+ A+++ +D + NTPLHIA R+G+E + L+ +A+ G GM P+H+A + F +C C L + TH D GR +H A AGG+L+CL ++ G D + +D +TPLH A N+ L+ GAS++ DE C +HYAA + +G AN + ++ + L ++ N + K VH+A G+ L LE+ + ND +++ + S +HLAAYHGH + L LVQ + ++ +GRT L LAA++GH V L++ GA D +H AA G + L +I + ++ + VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECV+ LL NA L D RGR ++AA+ GH +L L+ I ++ + ++ + Y TPLH+A GH C+E+L E K + LHCA+ + + E ++ ++N+ D TP+ A D++ L+ L+ HNA +N D G TP+M+AA+ G S + +L+ L DK+ LH A ++ ++ILE++ + LIN+ ++ QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA
Sbjct: 7 LPPLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEDAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHVEMVSLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVTHGAEVMCKDKKSYTPLHAAASSGMISVIKYLLDLGVDMNESNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GANVNQVNERGFTPLHFAAASTHGALCLELLVCNGADVNIKSKDGKTPLHMTAIHGRFSRSQIIIQNGAEIDCEDKNGNTPLHIAARYGHELLINTLITSRADTSKRGIHGMFPLHLAALSGFSDC-CRKLLSSGFDIDTH------DDFGRTCLHAAAAGGNLECLNLLLSTGADFNKKDKFGRTPLHYAAANCNYQCLFALVGSGASVNDLDERGCSPLHYAATSDTDGK---------ANHVKANHVKEQTALCLEYLLRNDANPGIRDKHGYNAVHYAAAYGHR----LCLELTSGTDML-----------NDAETRAPI-SPLHLAAYHGHHQALEVLVQSLLD--LDVRNSTGRTPLDLAAFKGHVECVDVLINQGASILVKDYVVKRTPIHSAAINGHSECLRLLIGNADVQ---AAVDIHDGNGQTPLMLSVLNGHTECVYSLLNKGANVDAKDKWGRTALHRGVMTGHEECVEALLQHNANFLLRDCRGRTPIHLAAACGHIGVLSALLQTA---------------ISVDVVPAIADNHGY-TPLHWACYNGHDACVELLLEQEVFQKMEGNSFSPLHCAVINDNEGAAEMLIDTLGTSIVNSVDSKGRTPLHAAAFTDHIECLQLLLSHNAQVNAVDSTGKTPLMMAAENGQTSAVEVLVSSAKADLTLQDKNKNTALHLACSKGHETSALLILEQI-TDRNLINATNSALQTPLHVAARNGLTVVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILA 982
BLAST of Ankyrin repeat domain 28b vs. Ensembl Mouse
Match: Ankrd28 (ankyrin repeat domain 28 [Source:MGI Symbol;Acc:MGI:2145661]) HSP 1 Score: 511.531 bits (1316), Expect = 4.262e-161 Identity = 348/1067 (32.61%), Postives = 540/1067 (50.61%), Query Frame = 1
Query: 61 NIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD---VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
N++P+L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + +L+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH E+VK+LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI + +N +N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I++ A ++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D ++PLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K+ VH++ G+ L L+++ +E +D + +++S D S D +S +HLAAYHGH + L LVQ + ++ SGRT L LAA++GH V L++ GA D +H AA+ G + L +I + + +N VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECVD LL AK L D RGR +++A+ GH +L G ++ + + N D T LH+A GH C+E+L E K + LHCA+ + + E ++ ++N D TP+ A D+V L+ L+ NA +N D G TP+M+AA+ G + + +L+ + L DKS LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M
Sbjct: 37 NVLPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANP----GIRD----------------KQGYNAVHYSAAYGHR----LCLQLIASETPLDVL---METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLD--LDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYVLKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVL-------------GALLQSATSVDAN---PAVVDNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFSPLHCAVINDNEGAAEMLIDSLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSSASADLTLQDKSKNTALHLACGKGHETSALLILEKI-TDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 1014
BLAST of Ankyrin repeat domain 28b vs. Ensembl Mouse
Match: Ankrd28 (ankyrin repeat domain 28 [Source:MGI Symbol;Acc:MGI:2145661]) HSP 1 Score: 507.294 bits (1305), Expect = 8.323e-160 Identity = 347/1064 (32.61%), Postives = 537/1064 (50.47%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD---VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
P+L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + +L+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH E+VK+LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI + +N +N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I++ A ++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D ++PLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K+ VH++ G+ L L+++ +E +D + +++S D S D +S +HLAAYHGH + L LVQ + ++ SGRT L LAA++GH V L++ GA D +H AA+ G + L +I + + +N VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECVD LL AK L D RGR +++A+ GH +L G ++ + + N D T LH+A GH C+E+L E K + LHCA+ + + E ++ ++N D TP+ A D+V L+ L+ NA +N D G TP+M+AA+ G + + +L+ + L DKS LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M
Sbjct: 10 PSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDAN----PGIRD----------------KQGYNAVHYSAAYGHR----LCLQLIASETPLDVL---METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLD--LDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYVLKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVL-------------GALLQSATSVDAN---PAVVDNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFSPLHCAVINDNEGAAEMLIDSLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSSASADLTLQDKSKNTALHLACGKGHETSALLILEKI-TDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 984
BLAST of Ankyrin repeat domain 28b vs. Ensembl Mouse
Match: Ankrd44 (ankyrin repeat domain 44 [Source:MGI Symbol;Acc:MGI:3045243]) HSP 1 Score: 447.973 bits (1151), Expect = 4.565e-138 Identity = 327/1049 (31.17%), Postives = 512/1049 (48.81%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDN------VTLKTHINNLD-------DDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGD--ILRLLFDNGANILSPININDH-----LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD--VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGA 3150
P L +I D + +R ++ DVN D+ +T LH+AA++G++ I ++LI G VN+KD +TPL +A AS S + VLI AD N RD W HV AA+ +V C ++I+P + +N++D GRTALHHA NGH+E+V +LL +I+A DK R +HWAA G L+++ LL+++ A + +DK YT LH A++ G I +V L+ G E+D + GN ALH+A N +V ELI + +N N G T LH + + C++LL+ GA+ N+ S++GKSPLH A + ++ LI+ +++ D NTPLH+A R G+E + L+ A+ G M P+H+A + C KLL + V+L ++ + L D GR +H A AGG+++C++ + G D H +D +TPLH A +F + L+ GA+++ D++ A+HYAA + + + IL DN + + + L F+ N + + K+ +H+A G+ + LLLE + ++ D + S +HLAAY+GH + L L+Q + +D GRTAL+LAA++GH V+ L++ GA D LH + G L L ++ + +VD D ++PLM+AV GH L+ A+VD D G T+LHR GH ECV +LL+ A I D RGR + AA+ GH L +L+ I ++E D TPLH+A G+ NCIE+L E K T LHCAI + + +L + +++ D T + A D+ L+ L+ H+A +N D +G T +M+AA+ G +++L+ + DK LH A + C ++IL+K+ + LIN+ ++ QTP H+AA N L + + L+ GA
Sbjct: 10 PPLVQAIFSGDPEEIRMLIHKTEDVNALDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHMEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQISVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELID-----------------------------------YGANVNQPNNSGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARHGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGQKYSIVSLFSNEHVLSAGFEIDTPDTFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIKALVTTGANVNETDDWGRTALHYAAASDMDRNKMILGNAHDNSEELERAREVKEKDAALCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLE----------------RTNTGFEESDGGALKSPLHLAAYNGHHQALEVLLQSLVD--LDIRDEKGRTALYLAAFKGHTECVEALVNQGASIFVKDNVTKRTPLHASVINGHTLCLR---LLLETADNPEVVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDAVDIVGCTALHRGIMTGHEECVQMLLEQEASILCKDSRGRTPLHYAAARGHATWLNELLQ-----------------IALSEEDCCLKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPFTPLHCAIINGHESCASLLLGAIDPSIVSCRDDKGRTTLHAAAFGDHAECLQLLLRHDAQVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLAISKGHEKCALLILDKIQ-DESLINAKNSALQTPLHIAARNGLKVVVEELLAKGA 984 HSP 2 Score: 214.542 bits (545), Expect = 2.231e-56 Identity = 254/963 (26.38%), Postives = 415/963 (43.09%), Query Frame = 1
Query: 142 VNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSD--GRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXX-XXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSS------HLFLEHLKS-NSHQDLIEEI--KDNHFVLIK----ERLESI---LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIAC------------------------RFGYEKFVQMLLEY----KANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLG-RNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHA--INVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLEN---RKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLI--MNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNG 2865
VN+ D +TALH AA G+ + ++L+ G ++N+ D L A +V+ +LI+ GA+ C+D K H A++ + +K +L LG+ I + + G TALH A NG VV L+D +++ + +G P+H+AAA + L LL++N A++NI+ KD + LH+ + G LI+ G E+DCV GN LH+A+ + H ++ LI + + +F HL + N+H D ++ + ++ E + S +++ + G T LH + N +C+ LL + GA+ + + G++PLH+AA+ L+ A+VN DD T LH A R EK + LE+ AN + ++G IH A A+ + C+ LL+ +T+ + DG ++ +H A G + LE +++ D+ D +T L+LA + L+ GASI V+D T +A++ N LRLL + N +++ D K P+ AV G+ D + LLLE N +D + + +H GH E + L++ + + +D GRT LH AA +GHA +N ++ + + + + LH+A G NE + V LE RK + + +PL A+ NGH A L+ ++ + V +D GRT+LH A H EC+ LLL +A++ D G+ A MAA G + L+N Q D K D+D TPLH A S+GH C ++ + KI + LIN + TP+ A + +E+L+ A + D N
Sbjct: 133 VNVSDRGGRTALHHAALNGHMEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQISVVKHLLN--LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNSGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARHGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGQKYSIVSLFSNEHVLSAGFEIDTPDTFGRTCLHAAAAGGNV-ECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIKALVTTGANVNETDDWGRTALHYAAASDMDRNKMILGNAHDNSEELERAREVKEKDAALCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLE----RTNTGFEESDGGALKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALYLAAFKGHTECVEALVNQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLETADNP-EVVDVKD----------------AKGQTPLMLAVAYGHIDAVSLLLEKEANVDAVDIVG----------------CTALHRGIMTGHEECVQMLLE--QEASILCKDSRGRTPLHYAAARGHATWLNELLQIALSEEDCCLKDNQGYTPLHWACYNG-----NENCIEVLLEQKCFRKFIGNPF-----TPLHCAIINGHESCASLLLGAIDPSIVSCRDDKGRTTLHAAAFGDHAECLQLLLRHDAQVNAVDNSGKTALMMAAENGQAGAVDILVNSA-----QADLTVK--------------DKDLNTPLHLAISKGHEKCALLILD-------------------------------KIQDESLINAKNSALQTPLHIAARNGLKVVVEELLAKGACVLAVDENA 993 HSP 3 Score: 134.035 bits (336), Expect = 3.715e-31 Identity = 127/451 (28.16%), Postives = 199/451 (44.12%), Query Frame = 1
Query: 1903 AAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYW-NALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFM-TFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPI-FYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAA 3246
A + G E + L I V+ D RT LH+AA+ G A ++ L+ GA+ A KD W LH A + S +A+ +I + V++ D++ ++PL +A N + AE +I + V++ D GRT+LH A NGH+E V+LLL A I FD + R A + AA GH +++ LIN+ A + D+ TPLH AAS G + ++ L L E+ N + T LH A + D + ++ N +N P+ +TP+ F A LE L+ + AD+N Q +G +P+ + A G + +Q ++ G+ I+ +D + TP H+AA + L +N LIT GAD S P+ N+ SDC L++
Sbjct: 15 AIFSGDPEEIRML--IHKTEDVNALDSEKRTPLHVAAFLGDAEIIELLILSGARVNA--KDNMWLTPLHRAVASRSEEAVQVLI------KHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHMEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGA--------------------EVTCKDKKGYTPLHAAASNGQISVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN--VNQPNNSGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFT------------------RSQTLIQNGGE--------------------IDCVDKDGNTPLHVAARHGHELLINTLITSGADTAKCGIHSMFPLHLAALNAH-SDCCRKLLSS 394 HSP 4 Score: 124.02 bits (310), Expect = 4.872e-28 Identity = 179/734 (24.39%), Postives = 294/734 (40.05%), Query Frame = 1
Query: 1348 INNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTA-EKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYE----------LSDEMKSTNGF---------MTFLHCAIDSKCDETLECV--LKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAA-----------------------------KEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFN----SLPLFLNALITFG-------ADLYLKNFKSQLPIVSCGRNSKASDCIE------------------ICLAAMFSSTDSPANLALKTSLNLSP 3309
+N LD + R +H A G + +E +I G ++ +DN+ TPLH AV + ++LIK A ++ D+ +H AA NK ++ +LS +N++D G + +H A ++G+ + + LLL KG ++ N + KD +H AAY GH +++ L+ ++ V+ +D+ G T LH AA G VK LL+ G + ++ Y ALH A G +NE+I + + V+ + +PL A + H E L+ NGADV+++ G++ LH +G L+ +I+ D G ++AA GH+ L+ LI A+ G H +F PLH AA H++C L S+E + GF T LH A +EC+ L+ + D + DK TP+ YA + + + ++ L+ A++N D G T + AA K+ L CL LL+ ++ DK N +HYA C ++LE+ S ++P HLAA+N +L + L +L+ LYL FK V N AS ++ +CL + + D+P + +K + +P
Sbjct: 34 VNALDSEK--RTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAA-NKAVKCAEVIIP----LLSSVNVSDR--------------GGRTA--LHHAALNGHMEMVNLLLA-----------KG---ANINAFDKKDR--RALHWAAYMGHLDVVALLINHGAE--VTCKDKKGYTPLHAAASNGQISVVKHLLNLGVEIDEINV-YGNTALHIACYNGQDAVVNELI------DYGANVNQPNNSGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARHGHELLINTLITSGADTAKCG-----IHSMF---------------PLHLAALNAHSDCCRKLLSSGQKYSIVSLFSNEHVLSAGFEIDTPDTFGRTCLHAAAAGG---NVECIKLLQSSGADF-HKKDKCGRTPLHYAAANCHFHCIKALVTTGANVNETDDWGRTALHYAAASDMDRNKMILGNAHDNSEELERAREVKEKDAAL-CLEFLLQ-NDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTN--TGFEESDGGALKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALYLAAFKGHTECVEALVNQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLETADNPEVVDVKDAKGQTP 691 HSP 5 Score: 104.375 bits (259), Expect = 5.437e-22 Identity = 139/583 (23.84%), Postives = 241/583 (41.34%), Query Frame = 1
Query: 136 LDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNR-AFHVCAA-------------HNSVD---------------CLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLD-NNTSISASDKNGVR-PIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILN--SRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQ---LKQAVLLIKAKADVNIQDDHENTPLHIAC------------------RF--------------GYEKFVQMLLEYKANAFVAGED--GMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLV--------------------------------HCAVAGGSLKCLETIIRLGGD---IHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDE 1569
+++ D + +T LH AA GN +L G D + KD G TPL A A+ + + L+++GA+ N D+ W R A H AA H++ + CL+ +L + +I D +G ++H+A A GH + +++LL+ NT SD ++ P+H AA G + L +LL + +++IRD+ TAL++A+ GH + V L+ +GA + AS N + L+ + ++ + L+ + H + LE N + + G T+LH M +CV +LL A+ G++PLH+AA+R L + + + ++ D ++D+ TPLH AC +F G+E +LL + V+ D G +H A + C+ LL + +N +D+ G ++ H A++ G KC I+ D I+ +++ QTPLH+A + ++ L+ GA + DE
Sbjct: 414 FEIDTPDTFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIKALVTTGANVNETDD-WGRTALHYAAASDMDRNKMILGNAHDNSEELERAREVKEKDAALCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNTGFEESDGGALKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALYLAAFKGHTECVEALVNQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLETADNPEVVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDAVDIVGCTALH-RGIMTGHEECVQMLLEQEASILCKDSRGRTPLHYAAARGHATWLNELLQIALSEEDCCLKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPFTPLHCAIINGHESCASLLLGAIDPSIVSCRDDKGRTTLHAAAFGDHAECLQLLLRH---DAQVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLAISKGHEKCALLILDKIQDESLINAKNSALQTPLHIAARNGLKVVVEELLAKGACVLAVDE 991
BLAST of Ankyrin repeat domain 28b vs. Ensembl Mouse
Match: Ankrd52 (ankyrin repeat domain 52 [Source:MGI Symbol;Acc:MGI:2444029]) HSP 1 Score: 439.113 bits (1128), Expect = 4.068e-134 Identity = 330/1139 (28.97%), Postives = 523/1139 (45.92%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNC---------------------------------RDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDD-------------DGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAA---MYNKEGDILRLLFDNGANILSPININDH----LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAM--FSSTD--SPANLALKTSLNLSPKK 3315
P L +I D + +R L K ++N+ D +T LH AAY+G+ I L +L+ SGA+ N RD W HV AA+ + C + + P + +N+ D GR+ALHHAV +GH+E V +LL+ S++ DK +P+HWAA G LE+L LL+ A+++ +D+ Y LH A+A G I++V L+ GAE+D GN ALH+A + EL+ A + +N N +G T LH+ + N C++LL+ GA+ N S+ GKSPLH AA + ++ +LI+ ++++ D NTPLH+A R+G+E + L+ A+ G M P+H+A F C KLL + L + +++L + D LGR +H A +GG+++CL ++ G D+ D +TPLH A ++ L+ GA ++ D C +HYAA Y + D + L + L F+ +N D + ++ VH+A GN + LLLEM +C++ D +S V S +HLAAY+GH E L L + + +D GRTAL LA +G V+ L + GA ++ W LH AA+ G D+L+ +I S + R + D +D + ++PLM+A+ NGH L+ G+ D D GRT+LHR G +C+ LLD +A + DF+GR ++A++ GH +L L+ Q D + D +P+H+A+ GH +C+E+L E S T LHCA+ + D T E +L ++N+ D TP+ A DNV+ L L+ H A++N D G T +M AA+ G + + LL ++D++ LH A + C ++IL + L LIN+ ++ Q P H+AA N L + AL++ GA + + + P ++C N +DC+ + L+ M F D SP + +L + ++ K
Sbjct: 10 PPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPI---------------------------------LQLLLMSGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLSCKDRKGYGLLHTAAASGQIEVVKHLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNA-----------------------------------GANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVNYQSKEGKSPLHMAAIHGRFTRSQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDSLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTYRRAEPHTASSHDAEEDELLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEM-----SFNCLE--------DVESTVPV-SPLHLAAYNGHCEALKTLAETLVN--LDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGE---RADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLL--------QAALSTDPLDAGV--------DYSGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDAKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAESGQTAAVEFLLYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDL-GLINATNSALQMPLHIAARNGLASVVQALLSRGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKPFPPKDAVSPFSFSLLKNCGIAAAK 1044 HSP 2 Score: 147.132 bits (370), Expect = 3.963e-35 Identity = 202/802 (25.19%), Postives = 322/802 (40.15%), Query Frame = 1
Query: 1045 NLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI----------------LSPININDHL-----SFIENNIMDNTS------LGKKIV-------------------YPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSL-DEH--------------KRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINE--LKSMWF---------------DQDYLTPLHFAASRGHTNCIEMLYELS----DEMKSTNGFMTFLHCAIDSKCD------ETL-----------------------EC--VLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLI--LHNADI-NYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAA 3102
+LS + PL A +++ L+ K ++N+ D TPLH A G +Q+LL AN + P+H A A +N + LL + +N D L + +H A A + KC E + L ++ D ++ LH AV + +L+ GAS++V D+ +H+AA ++L+LL GA++ I + HL E N NT+ LG+ V P+H A +S N L LE++ N + + +YQSK+ S +H+AA HG L+Q S+ + D+ G T LH+AA GH + + L++ GA TA + LH A G D +++ S +L S+V SL +EH R+ L A G+ L+ +GAD+ +D +GRT LH A ANG +C L+ A + D +G + + AA++ Y + H + D + E K +F D+ T +H+AA+ G+ +E+L E+S ++++ST A + C+ ETL EC VL + K WTP+ A + ++L LI ADI + D G TP+M+A G + C++LLLE + A D + LH + + C +L+ + D +TP HLA+
Sbjct: 2 GILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAH---SADVNARDK--LWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHL-EVLKLLVARGADLSCKDRKGYGLLHTAAASGQIEVVKHLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNG---ALCLELLVN-----------NGADVNYQSKEGK-SPLHMAAIHGRFTRSQILIQNGSE--IDCADKFGNTPLHVAARYGHELLISTLMTNGAD-TARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQL---YSIVSSLSNEHVLSAGFDINTPDSLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASD---------TYRRAEPHTASSHDAEEDELLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTVPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADA-ADLRGRTALHRGAVTGCEDCLAALLDH----DAFVLCRDFKGRTPIHLAS 762
BLAST of Ankyrin repeat domain 28b vs. Ensembl Mouse
Match: Ankrd44 (ankyrin repeat domain 44 [Source:MGI Symbol;Acc:MGI:3045243]) HSP 1 Score: 398.282 bits (1022), Expect = 6.248e-120 Identity = 313/1070 (29.25%), Postives = 494/1070 (46.17%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIAD---------------------------------ILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDN-VTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGD--ILRLLFDNGANILSPININDH-----LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD--VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGA 3150
P L +I D + +R ++ DVN D+ +T LH+AA++G++ I + +LIK+ DVN++D N TPL HV AA+ +V C ++I+P + +N++D GRTALHHA NGH+E+V +LL +I+A DK R +HWAA G L+++ LL+++ A + +DK YT LH A++ G I +V L+ G E+D + GN ALH+A N +V ELI + +N N G T LH + + C++LL+ GA+ N+ S++GKSPLH A + ++ LI+ +++ D NTPLH+A R G+E + L+ A+ G M P+H+A + C KLL + + T D GR +H A AGG+++C++ + G D H +D +TPLH A +F + L+ GA+++ D++ A+HYAA + + + IL DN + + + L F+ N + + K+ +H+A G+ + LLLE + ++ D + S +HLAAY+GH + L L+Q + +D GRTAL+LAA++GH V+ L++ GA D LH + G L L ++ + +VD D ++PLM+AV GH L+ A+VD D G T+LHR GH ECV +LL+ A I D RGR + AA+ GH L +L+ I ++E D TPLH+A G+ NCIE+L E K T LHCAI + + +L + +++ D T + A D+ L+ L+ H+A +N D +G T +M+AA+ G +++L+ + DK LH A + C ++IL+K+ + LIN+ ++ QTP H+AA N L + + L+ GA
Sbjct: 10 PPLVQAIFSGDPEEIRMLIHKTEDVNALDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPL---------------------------------HVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHMEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQISVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELID-----------------------------------YGANVNQPNNSGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARHGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDT------PDTFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIKALVTTGANVNETDDWGRTALHYAAASDMDRNKMILGNAHDNSEELERAREVKEKDAALCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLE----------------RTNTGFEESDGGALKSPLHLAAYNGHHQALEVLLQSLVD--LDIRDEKGRTALYLAAFKGHTECVEALVNQGASIFVKDNVTKRTPLHASVINGHTLCLR---LLLETADNPEVVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDAVDIVGCTALHRGIMTGHEECVQMLLEQEASILCKDSRGRTPLHYAAARGHATWLNELLQ-----------------IALSEEDCCLKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPFTPLHCAIINGHESCASLLLGAIDPSIVSCRDDKGRTTLHAAAFGDHAECLQLLLRHDAQVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLAISKGHEKCALLILDKIQ-DESLINAKNSALQTPLHIAARNGLKVVVEELLAKGA 966 HSP 2 Score: 219.55 bits (558), Expect = 5.713e-58 Identity = 257/975 (26.36%), Postives = 412/975 (42.26%), Query Frame = 1
Query: 76 LFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILL---------------------------------DNNTSISASDKNGVRPIHWAAARGXXXX-XXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSS------HLFLEHLKS-NSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIA------------------------CRFGYEKFVQMLLEY----KANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLG-RNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHA--INVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLEN---RKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLI--MNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNC-IEMLYELSDEM---KSTNGFMTFLHCAIDSKCDETLE-------CVLKIANN 2736
L ++ + ++ + + DVN +D QT LH+AA A+++I VN D G T L A + ++ +L++ GA+ N D K RA H A +D + L++ H + D G T LH A +NG I VVK LL D +++ + +G P+H+AAA + L LL++N A++NI+ KD + LH+ + G LI+ G E+DCV GN LH+A+ + H ++ LI + + +F HL + N+H D ++ + F +++ + G T LH + N +C+ LL + GA+ + + G++PLH+AA+ L+ A+VN DD T LH A R EK + LE+ AN + ++G IH A A+ + C+ LL+ +T+ + DG ++ +H A G + LE +++ D+ D +T L+LA + L+ GASI V+D T +A++ N LRLL + N +++ D K P+ AV G+ D + LLLE N +D + + +H GH E + L++ + + +D GRT LH AA +GHA +N ++ + + + + LH+A G NE + V LE RK + + +PL A+ NGH A L+ ++ + V +D GRT+LH A H EC+ LLL +A++ D G+ A MAA G + L+N Q D K D+D TPLH A S+GH C + +L ++ DE + T LH A + +E CVL + N
Sbjct: 78 LHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHMEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQISVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNSGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARHGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFE---------IDTPDTFGRTCLHAAAAGGNV-ECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIKALVTTGANVNETDDWGRTALHYAAASDMDRNKMILGNAHDNSEELERAREVKEKDAALCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLE----RTNTGFEESDGGALKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALYLAAFKGHTECVEALVNQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLETADNP-EVVDVKD----------------AKGQTPLMLAVAYGHIDAVSLLLEKEANVDAVDIVG----------------CTALHRGIMTGHEECVQMLLE--QEASILCKDSRGRTPLHYAAARGHATWLNELLQIALSEEDCCLKDNQGYTPLHWACYNG-----NENCIEVLLEQKCFRKFIGNPF-----TPLHCAIINGHESCASLLLGAIDPSIVSCRDDKGRTTLHAAAFGDHAECLQLLLRHDAQVNAVDNSGKTALMMAAENGQAGAVDILVNSA-----QADLTVK--------------DKDLNTPLHLAISKGHEKCALLILDKIQDESLINAKNSALQTPLHIAARNGLKVVVEELLAKGACVLAVDEN 974 HSP 3 Score: 139.043 bits (349), Expect = 1.152e-32 Identity = 136/488 (27.87%), Postives = 215/488 (44.06%), Query Frame = 1
Query: 1903 AAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYW-NALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFM-TFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPI-FYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGYVINLKEAELEGS 3357
A + G E + L I V+ D RT LH+AA+ G A ++ L+ GA+ A KD W LH A + S +A+ +I + V++ D++ ++PL +A N + AE +I + V++ D GRT+LH A NGH+E V+LLL A I FD + R A + AA GH +++ LIN+ A + D+ TPLH AAS G + ++ L L E+ N + T LH A + D + ++ N +N P+ +TP+ F A LE L+ + AD+N Q +G +P+ + A G + +Q ++ G+ I+ +D + TP H+AA + L +N LIT GAD S P+ N+ SDC L++ F D+P +T L+ + G V +K + G+
Sbjct: 15 AIFSGDPEEIRML--IHKTEDVNALDSEKRTPLHVAAFLGDAEIIELLILSGARVNA--KDNMWLTPLHRAVASRSEEAVQVLI------KHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHMEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGA--------------------EVTCKDKKGYTPLHAAASNGQISVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN--VNQPNNSGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFT------------------RSQTLIQNGGE--------------------IDCVDKDGNTPLHVAARHGHELLINTLITSGADTAKCGIHSMFPLHLAALNAH-SDCCRKLLSSGF-EIDTPDTFG-RTCLHAAAAGGNVECIKLLQSSGA 429 HSP 4 Score: 131.339 bits (329), Expect = 2.344e-30 Identity = 177/716 (24.72%), Postives = 293/716 (40.92%), Query Frame = 1
Query: 1348 INNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTA-EKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGF-MTFLHCAIDSKCDETLECV--LKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAA-----------------------------KEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFN----SLPLFLNALITFG-------ADLYLKNFKSQLPIVSCGRNSKASDCIE------------------ICLAAMFSSTDSPANLALKTSLNLSP 3309
+N LD + R +H A G + +E +I G ++ +DN+ TPLH AV + ++LIK A ++ D+ +H AA NK ++ +LS +N++D G + +H A ++G+ + + LLL KG ++ N + KD +H AAY GH +++ L+ ++ V+ +D+ G T LH AA G VK LL+ G + ++ Y ALH A G +NE+I + + V+ + +PL A + H E L+ NGADV+++ G++ LH +G L+ +I+ D G ++AA GH+ L+ LI A+ G H +F PLH AA H++C L E+ + + F T LH A +EC+ L+ + D + DK TP+ YA + + + ++ L+ A++N D G T + AA K+ L CL LL+ ++ DK N +HYA C ++LE+ S ++P HLAA+N +L + L +L+ LYL FK V N AS ++ +CL + + D+P + +K + +P
Sbjct: 34 VNALDSEK--RTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAA-NKAVKCAEVIIP----LLSSVNVSDR--------------GGRTA--LHHAALNGHMEMVNLLLA-----------KG---ANINAFDKKDR--RALHWAAYMGHLDVVALLINHGAE--VTCKDKKGYTPLHAAASNGQISVVKHLLNLGVEIDEINV-YGNTALHIACYNGQDAVVNELI------DYGANVNQPNNSGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARHGHELLINTLITSGADTAKCG-----IHSMF---------------PLHLAALNAHSDCCRKLLSSGFEIDTPDTFGRTCLHAAAAGG---NVECIKLLQSSGADF-HKKDKCGRTPLHYAAANCHFHCIKALVTTGANVNETDDWGRTALHYAAASDMDRNKMILGNAHDNSEELERAREVKEKDAAL-CLEFLLQ-NDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTN--TGFEESDGGALKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALYLAAFKGHTECVEALVNQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLETADNPEVVDVKDAKGQTP 673
BLAST of Ankyrin repeat domain 28b vs. UniProt/SwissProt
Match: sp|O15084|ANR28_HUMAN (Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5) HSP 1 Score: 516.538 bits (1329), Expect = 2.068e-162 Identity = 349/1064 (32.80%), Postives = 539/1064 (50.66%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD---VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
P+L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH E+VK+LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI +I+N +N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I++ A ++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D ++PLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K+ VH++ G+ L L+++ +E +D + +++S D S D +S +HLAAYHGH + L LVQ + ++ SGRT L LAA++GH V L++ GA D +H AA+ G + L +I + + +N VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECVD LL AK L D RGR +++A+ GH +L L+ A+ + D T LH+A GH C+E+L E K+ + LHCA+ + + E ++ ++N D TP+ A D+V L+ L+ HNA +N D G TP+M+AA+ G + + +L+ + + L D S LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M
Sbjct: 10 PSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDAN----PGIRD----------------KQGYNAVHYSAAYGHR----LCLQLIASETPLDVL---METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLD--LDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASM----------------DANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKI-TDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 984
BLAST of Ankyrin repeat domain 28b vs. UniProt/SwissProt
Match: sp|Q5ZLC8|ANR52_CHICK (Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C OS=Gallus gallus OX=9031 GN=ANKRD52 PE=2 SV=1) HSP 1 Score: 508.064 bits (1307), Expect = 4.051e-159 Identity = 343/1079 (31.79%), Postives = 540/1079 (50.05%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDD-------------DGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAA---MYNKEGDILRLLFDNGANILSPININDH---LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAM 3249
P L +I D + +R L K ++N+ D +T LH AAYIG+ I ++LI G +VN+KD +TPL +A AS + L +L+ AD N RD W HV AA+ + C++ I+P + +N+ D GRTALHHAV +GH+E+V +LL+ S+S DK +PIHWAA G LE+L LL+ A++ +DK YT LH A+A G I++V L+ G E+D + GN ALH+A + EL+ + +N N +G T LH + N C++LL+ GA+ N S+ GKSPLH AA + ++ +LI+ ++++ D + NTPLH+A R+G+E + L+ A+ G M P+H+A F C KLL + L + +++L + D LGR +H A +GG+++CL ++ G D+ D +TPLH A ++ T L+ GASI+ D C +HYAA Y + D L + + L F+ +N D + K+ VH+A GN + LLLEM +C++ D +S V S +HLAAY+GH E L L + + +D GRTAL+LA +G V+ L S GA ++ W LH AA+ G+ D+L+ +I S + R + D +D H ++PLM+A+ NGH L+ G+ D D GRT+LHR G +C+ LLD +A + DF+GR + A++ GH +L L+ + + L S+ D +P+H+A+ GH +C+E+L E + T LHCA+ + D T E +++ ++N+ D TP+ A DN++ L+ L+ H A+++ D G TP+M+A++ G + + LL ++D + LH A + C ++IL + L LIN+ ++ Q P H+AA N L + AL++ GA + + + P ++C N +DC+ + L+ M
Sbjct: 10 PPLVQAIFNRDVEEVRSLLNQKENINVLDQERRTPLHTAAYIGDVAILELLILSGANVNAKDTVWLTPLHRAAASRNEKALHLLLKHSADVNARDKYWQTPLHVAAANRATKCVEAIIPLLSTVNVADRTGRTALHHAVHSGHLEMVNLLLNKGASLSTCDKKDRQPIHWAAFLGHLEVLKLLVARGADVMCKDKKGYTLLHTAAASGQIEVVRHLLRLGVEIDEPNSFGNTALHIACYMGQDAVANELVN-----------------------------------YGANVNQPNEKGFTPLHFAAVSTNGALCLELLVNNGADVNFQSKEGKSPLHMAAIHGRFTRSQILIQNGSEIDCADKYGNTPLHVAARYGHELLISTLMTNGADTARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCTVTLVTAGASINEADCKGCTPLHYAAASDTYRRAETHSGNSHDTDEEPLKESRMKEAFFCLEFLLDNGADPSLRDKQGYTAVHYAAAYGNRQNLELLLEM-----SFNCLE--------DVESTIPV-SPLHLAAYNGHCEALKTLAETLVN--LDVRDHKGRTALYLATERGSTECVEVLTSHGASALVKERKRKWTPLHAAAANGNTDSLHLLIDSGE---RADITDVMDIHGQTPLMLAIMNGHVDCVHLLLEKGSTADAADKRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHFASACGHLEILRTLLQAA---------------LSTDPLDSV-VDYSGYSPMHWASYSGHEDCLELLLEHNPFAYLEGNPFTPLHCAVINNQDSTAEMLVEALGAKIVNSRDAKGRTPLHAAAFADNIHGLQLLLRHQAEVDTTDKLGRTPLMMASENGHTAAVEFLLYQAKANITVLDVNKNTALHLACSKGHEKCALLILGETQDL-GLINASNSALQMPLHIAARNGLATVVQALLSRGATVLAVDEEGHTPALACAPNKDVADCLALILSTM 1017 HSP 2 Score: 164.466 bits (415), Expect = 1.139e-39 Identity = 205/805 (25.47%), Postives = 333/805 (41.37%), Query Frame = 1
Query: 1048 LLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANIL----------------SPININDHLSFI-----ENNIMDNTSL-------------------------GKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSL-DEH--------------KRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHD-----IFINELKSMWF---------------DQDYLTPLHFAASRGHTNCIEMLYELS----DEMKST-----------NGF---------------------MTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLI--LHNADI-NYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAA 3102
+LS + PL A +++ L+ K ++N+ D TPLH A G +++L+ AN + P+H A A +N +H LL + +N D + +H A A + KC+E II L ++ D +T LH AV + + +L+ GAS+ D+ IH+AA ++L+LL GA+++ I + HL + E N NT+L +K P+HFA +S N L LE++ N + + ++QSK+ S +H+AA HG L+Q S+ + D+ G T LH+AA GH + + L++ GA TA + LH A G D +++ S +L S+V SL +EH R+ L A G+ L+ +GAD+ +D +GRT LH A ANG +C L+ A I D +G + AA++ Y + H G+ SHD + + +K +F D+ T +H+AA+ G+ +E+L E+S ++++ST NG T L+ A + E +E + + L+ K WTP+ A + N ++L LI ADI + D++G TP+M+A G + C++LLLE + A DK + LH + + C +L+ + D +TP H A+
Sbjct: 3 ILSITDQPPLVQAIFNRDVEEVRSLLNQKENINVLDQERRTPLHTAAYIGDVAILELLILSGANVNAKDTVWLTPLHRAAASRNEKALHLLLKH---SADVNARDK--YWQTPLHVAAANRATKCVEAIIPLLSTVNVADRTGRTALHHAVHSGHLEMVNLLLNKGASLSTCDKKDRQPIHWAAFLGHL-EVLKLLVARGADVMCKDKKGYTLLHTAAASGQIEVVRHLLRLGVEIDEPNSFGNTALHIACYMGQDAVANELVNYGANVNQPNEKGFTPLHFAAVSTNG---ALCLELLVN-----------NGADVNFQSKEGK-SPLHMAAIHGRFTRSQILIQNGSE--IDCADKYGNTPLHVAARYGHELLISTLMTNGAD-TARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQL---YSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCTVTLVTAGASINEADCKGCTPLHYAAASD---------TYRRAETHSGN----SHDTDEEPLKESRMKEAFFCLEFLLDNGADPSLRDKQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALYLATERGSTECVEVLTSHGASALVKE-RKRKWTPLHAAAANGNTDSLHLLIDSGERADITDVMDIHGQTPLMLAIMNGHVDCVHLLLEKGSTADA-ADKRGRTALHRGAVTGCEDCLAALLDH----DAFVLCRDFKGRTPIHFAS 761 HSP 3 Score: 143.665 bits (361), Expect = 3.579e-33 Identity = 200/821 (24.36%), Postives = 340/821 (41.41%), Query Frame = 1
Query: 136 LDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPL-FKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTS---------------------------------------------------ISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNS------RNYQGLTSLHILSQMDNAHQCVDLLLAYGAN--PNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVA-GEDGMLPIHVATAFKNCGCMHKLLDN--------------------VTLKTHINNLD-----------DDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVED---EYTCMAIHYAAMYNKEGDILRLLFDNG------ANILSPIN---INDHLSFIENNIMDNTSLGKKIV--------YPVHFAVMSGNFDGMILLLEMMPNEAKMDCI-------------KGHVDSSQND-YQSKDDVLSL-------IHLAAYHGHSEI-LNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSL 2196
++++ +++ TALH+A Y+G +A+ L+ YG +VN + G TPL F A ++N L +L+++GAD N + + H+ A H ++++ + I+ D G T LH A GH ++ L+ N I+ D G +H AA+ G++E LNLLL + A++ RDK T LH A+A G + L+ GA ++ +G LH A + ++ E NSH E +K++ LE +L++ R+ QG T++H + N Q ++LLL N ++ S SPLH AA + L + +++++D T L++A G + V++L + A+A V + P+H A A N +H L+D+ + H++ + D GR +H G CL ++ + D +TP+H A + I R L++ S D D +Y+ + + A Y+ D L LL ++ N +P++ IN+ S E M +LG KIV P+H A + N G+ LLL ++A++D GH + + YQ+K ++ L +HLA GH + L L + +++ + + + LH+AA G A V+ LLS GA AVD++ + AL A ++ D L ++ ++K K + S
Sbjct: 230 VEIDEPNSFGNTALHIACYMGQDAVANELVNYGANVNQPNEKGFTPLHFAAVSTNGALCLELLVNNGADVNFQSKEGKSPLHMAAIHGRFTRSQILIQNGSEIDCADKYGNTPLHVAARYGHELLISTLMTNGADTARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCTVTLVTAGASINEADCKGCTPLH--------------YAAASDTYRRAETHSGNSHDTDEEPLKESRMKEAFFCLEFLLDNGADPSLRDKQGYTAVHYAAAYGN-RQNLELLLEMSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALYLATERGSTECVEVLTSHGASALVKERKRKWTPLHAAAANGNTDSLHLLIDSGERADITDVMDIHGQTPLMLAIMNGHVDCVHLLLEKGSTADAADKRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHFASACGHLEILRTLLQAALSTDPLDSVVDYSGYSPMHWASYSGHEDCLELLLEHNPFAYLEGNPFTPLHCAVINNQDSTAE---MLVEALGAKIVNSRDAKGRTPLHAAAFADNIHGLQLLLR---HQAEVDTTDKLGRTPLMMASENGHTAAVEFLLYQAKANITVLDVNKNTALHLACSKGHEKCALLILGETQDLGLINASNSALQMPLHIAARNGLATVVQALLSRGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKPFPPKDAISSF 1029
BLAST of Ankyrin repeat domain 28b vs. UniProt/SwissProt
Match: sp|Q505D1|ANR28_MOUSE (Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Mus musculus OX=10090 GN=Ankrd28 PE=1 SV=1) HSP 1 Score: 507.294 bits (1305), Expect = 5.822e-159 Identity = 347/1064 (32.61%), Postives = 537/1064 (50.47%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD---VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
P+L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + +L+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH E+VK+LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI + +N +N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I++ A ++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D ++PLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K+ VH++ G+ L L+++ +E +D + +++S D S D +S +HLAAYHGH + L LVQ + ++ SGRT L LAA++GH V L++ GA D +H AA+ G + L +I + + +N VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECVD LL AK L D RGR +++A+ GH +L G ++ + + N D T LH+A GH C+E+L E K + LHCA+ + + E ++ ++N D TP+ A D+V L+ L+ NA +N D G TP+M+AA+ G + + +L+ + L DKS LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M
Sbjct: 10 PSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDAN----PGIRD----------------KQGYNAVHYSAAYGHR----LCLQLIASETPLDVL---METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLD--LDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYVLKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVL-------------GALLQSATSVDAN---PAVVDNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFSPLHCAVINDNEGAAEMLIDSLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSSASADLTLQDKSKNTALHLACGKGHETSALLILEKI-TDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 984
BLAST of Ankyrin repeat domain 28b vs. UniProt/SwissProt
Match: sp|Q8NB46|ANR52_HUMAN (Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C OS=Homo sapiens OX=9606 GN=ANKRD52 PE=1 SV=3) HSP 1 Score: 493.041 bits (1268), Expect = 2.234e-153 Identity = 343/1108 (30.96%), Postives = 543/1108 (49.01%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDD-------------DGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAA---MYNKEGDILRLLFDNGANILSPININDH------LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAM--FSSTD--SPANLALKTSLNLSPKK 3315
P L +I D + +R L K ++N+ D +T LH AAY+G+ I +L+ G +VN+KD +TPL +A AS + VL +L++ AD N RD W HV AA+ + C + + P + +N+ D GR+ALHHAV +GH+E V +LL+ S++ DK +P+HWAA G LE+L LL+ A++ +D+ Y LH A+A G I++V L+ GAE+D GN ALH+A + EL+ A + +N N +G T LH+ + N C++LL+ GA+ N S+ GKSPLH AA + ++ +LI+ ++++ D NTPLH+A R+G+E + L+ A+ G M P+H+A F C KLL + L + +++L + D LGR +H A +GG+++CL ++ G D+ D +TPLH A ++ L+ GA ++ D C +HYAA Y + D A P+ + L F+ +N D + ++ VH+A GN + LLLEM +C++ D +S V S +HLAAY+GH E L L + + +D GRTAL LA +G V+ L + GA ++ W LH AA+ G D+L+ +I S + R + D +D + ++PLM+A+ NGH L+ G+ D D GRT+LHR G +C+ LLD +A + DF+GR ++A++ GH +L L+ Q D + D +P+H+A+ GH +C+E+L E S T LHCA+ + D T E +L ++N+ D TP+ A DNV+ L L+ H A++N D G T +M AA+ G + + LL ++D++ LH A + C ++IL + L LIN+ ++ Q P H+AA N L + AL++ GA + + + P ++C N +DC+ + L+ M F D SP + +L + +++ K
Sbjct: 10 PPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNA-----------------------------------GANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVNYQSKEGKSPLHMAAIHGRFTRSQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTYRRAEPHTPSSHD--AEEDEPLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEM-----SFNCLE--------DVESTIPV-SPLHLAAYNGHCEALKTLAETLVN--LDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGE---RADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLL--------QAALSTDPLDAGV--------DYSGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDAKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDL-GLINATNSALQMPLHIAARNGLASVVQALLSHGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKPFPPKDAVSPFSFSLLKNCSIAAAK 1044 HSP 2 Score: 142.51 bits (358), Expect = 6.433e-33 Identity = 200/802 (24.94%), Postives = 322/802 (40.15%), Query Frame = 1
Query: 1045 NLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGAN----------ILSPININDHLSFI-----------ENNIMDNTS------LGKKIV-------------------YPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSL-DEH--------------KRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINE--LKSMWF---------------DQDYLTPLHFAASRGHTNCIEMLYELS----DEMKSTNGFMTFLHCAIDSKCD------ETL-----------------------EC--VLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLI--LHNADI-NYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAA 3102
+LS + PL A +++ L+ K ++N+ D TPLH A G +Q+LL AN + P+H A A +N + LL + +N D L + +H A A + KC E + L ++ D ++ LH AV + +L+ GAS++V D+ +H+AA ++L+LL GA+ +L + + + E N NT+ LG+ V P+H A +S N L LE++ N + + +YQSK+ S +H+AA HG L+Q S+ + D+ G T LH+AA GH + + L++ GA TA + LH A G D +++ S +L S+V SL +EH R+ L A G+ L+ +GAD+ +D +GRT LH A ANG +C L+ A + D +G + + AA++ Y + H + D + E K +F D+ T +H+AA+ G+ +E+L E+S ++++ST A + C+ ETL EC VL + K WTP+ A + ++L LI ADI + D G TP+M+A G + C++LLLE + A D + LH + + C +L+ + D +TP HLA+
Sbjct: 2 GILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAH---SADVNARDK--LWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHL-EVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNG---ALCLELLVN-----------NGADVNYQSKEGK-SPLHMAAIHGRFTRSQILIQNGSE--IDCADKFGNTPLHVAARYGHELLISTLMTNGAD-TARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQL---YSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASD---------TYRRAEPHTPSSHDAEEDEPLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADA-ADLRGRTALHRGAVTGCEDCLAALLDH----DAFVLCRDFKGRTPIHLAS 762
BLAST of Ankyrin repeat domain 28b vs. UniProt/SwissProt
Match: sp|Q502K3|ANR52_DANRE (Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C OS=Danio rerio OX=7955 GN=ankrd52 PE=2 SV=1) HSP 1 Score: 487.649 bits (1254), Expect = 2.017e-151 Identity = 342/1089 (31.40%), Postives = 544/1089 (49.95%), Query Frame = 1
Query: 52 MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELI-KALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTL--------KTHINNLD-----DDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFI-ENNIMDNTS----LGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSD-EMKSTNGFMTFLHCAIDSKCDETLECVLKIA-NNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKL--PCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAM 3249
+N + P L +I ++D ++ L+ K +VN D +T LH AA++G+ +I D+LI G +VN+KD +TPL +A AS + + +L+ GAD RD W H+ AA+ + C++ +LPHV +N+ D GR LHHA +G+ E+VK+LL+ ++SASDK +PIHWAA G LE++ LL+ ++ + +DK YT LH A+A GH+D+V L+ GAE+D GN ALH+A + EL+ + N +N N++G T LH+ + N C++LL+ GA+ N+ S+ GKSPLH AA + ++ +LI+ +++ D + NTPLH+A ++G+E + L+ A+ G GM P+H+A + + C KLL + L K H+ + D GR +H A +GG+++CL ++ G D++ +D +TPLH A + +L+ GA ++ D C +HY+A R N + SF+ +++DN + K VH+A GN + LLLEM N + D +S + S +HLA GH E + L++ S V D GR+ L+LA+ +GH+ V+ LLS A + W LH AA+ G + L ++ S E LV+ D ++PLM+AV GHT L+ GA D+KD GRT+LHR G +C+ LL N + DF+GR+A ++AAS GH ++L L++ + Q D+ TP H+AA GH +C+E+L EL ++ N F T LHCA+ + + E +L+ + N L+N D TP+ A ++V L+ ++ ADI+ D +G + +M+AA G + LLL +L+D + LH A A + C ++IL+++ P LIN+ ++ Q P H+AA N L + AL+ GA + + + P ++C N +DC+ + L+ M
Sbjct: 4 LNISDQPPLVQAIFNRNADEVKLFLHKKDEVNALDQERRTPLHAAAWLGDVHIMDLLISAGANVNAKDHVWLTPLHRAAASRNERAVGLLLRKGADVTARDKYWQTPLHIAAANRATRCVETLLPHVSSLNMADRTGRAPLHHAAQSGYQEMVKLLLNKGANLSASDKKDRQPIHWAAYLGHLEVVKLLVSQGSDKSCKDKRGYTPLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYTGQEAVANELVNRGAN------------------------------------VNQPNHRGYTPLHLAAVSTNGALCLELLVNNGADVNMQSKEGKSPLHMAAIHGRFTRSQILIQNGGEIDCVDRYGNTPLHVAAKYGHELLISTLMTNGADTARQGIHGMFPLHLAVLYGSSDCCRKLLSSGQLYSIVLSMSKEHVLSAGFDINTPDNFGRTCLHAAASGGNIECLNLLLSSGADMNKKDKFGRTPLHYAAANGRYQCVVVLVGAGAEVNERDRSGCTPLHYSAASTAFCRTDRPHASTHQN----QEDGEKESFLCVEHLLDNGADPCLCNTKGYSAVHYAAAHGNKQNLELLLEMCFN-------------TLGDKESNGSI-SPLHLAVESGHWECVTVLIE--SGVCVDVCDPVGRSVLYLASQRGHSRCVELLLSQSASCLLAEHRSKWGPLHVAAANGHSECLRMLLCS---EGGADLVNVTDAEGQTPLMLAVLGGHTDCVHLLLERGACPDMKDRRGRTALHRGAVMGREDCLTALLSHNVSVLSRDFQGRSALHLAASCGHADILSNLLSAADHSQPQDPLT----------------DRHGYTPAHWAAYHGHEDCLEVLLELKPCSIQEGNPF-TPLHCALINGHSGSAELLLESSVCNSLVNIRDAKGRTPLHAAAVAEDVAGLQLVLRQGADIDAVDHSGRSALMVAADYGQSGAVALLLHRAKADLSLLDVNKNTALHLACSKAHEMCAMLILKEIHNPI---LINATNSMLQMPLHIAARNGLATVVQALLNRGATVLAVDEEGHTPALACASNKAVADCLALILSTM 1013
BLAST of Ankyrin repeat domain 28b vs. TrEMBL
Match: A0A2K6SJ95 (Ankyrin repeat domain 28 OS=Saimiri boliviensis boliviensis OX=39432 GN=ANKRD28 PE=4 SV=1) HSP 1 Score: 520.776 bits (1340), Expect = 1.471e-161 Identity = 352/1070 (32.90%), Postives = 542/1070 (50.65%), Query Frame = 1
Query: 52 MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD---VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
M I+P+L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH E+VK+LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI +I+N +N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I++ A ++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D ++PLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K+ VH++ G+ L L+++ +E +D + +++S D S D +S +HLAAYHGH + L LVQ + ++ SGRT L LAA++GH V L++ GA D +H AA+ G + L +I + + +N VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECVD LL AK L D RGR +++A+ GH +L L+ A+ + D T LH+A GH C+E+L E K+ + LHCA+ + + E ++ ++NT D TP+ A D+V L+ L+ HNA +N D G TP+M+AA+ G + + +L+ + L D S LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M
Sbjct: 1 MGIPIMPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANP----GIRD----------------KQGYNAVHYSAAYGHR----LCLQLIASETPLDVL---METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLD--LDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASM----------------DANPAIADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNTTDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASADLTLQDNSKNTALHLACSKGHETSALLILEKI-TDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 981
BLAST of Ankyrin repeat domain 28b vs. TrEMBL
Match: A0A2K6SJB6 (Ankyrin repeat domain 28 OS=Saimiri boliviensis boliviensis OX=39432 GN=ANKRD28 PE=4 SV=1) HSP 1 Score: 520.776 bits (1340), Expect = 2.691e-161 Identity = 351/1067 (32.90%), Postives = 542/1067 (50.80%), Query Frame = 1
Query: 61 NIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD---VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
N++P+L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH E+VK+LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI +I+N +N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I++ A ++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D ++PLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K+ VH++ G+ L L+++ +E +D + +++S D S D +S +HLAAYHGH + L LVQ + ++ SGRT L LAA++GH V L++ GA D +H AA+ G + L +I + + +N VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECVD LL AK L D RGR +++A+ GH +L L+ A+ + D T LH+A GH C+E+L E K+ + LHCA+ + + E ++ ++NT D TP+ A D+V L+ L+ HNA +N D G TP+M+AA+ G + + +L+ + L D S LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M
Sbjct: 37 NVLPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANP----GIRD----------------KQGYNAVHYSAAYGHR----LCLQLIASETPLDVL---METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLD--LDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASM----------------DANPAIADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNTTDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASADLTLQDNSKNTALHLACSKGHETSALLILEKI-TDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 1014
BLAST of Ankyrin repeat domain 28b vs. TrEMBL
Match: A0A5G3L9P7 (REV1, DNA directed polymerase OS=Xenopus tropicalis OX=8364 GN=rev1 PE=4 SV=1) HSP 1 Score: 519.62 bits (1337), Expect = 3.450e-161 Identity = 344/1061 (32.42%), Postives = 540/1061 (50.90%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVA--TAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQ-NDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLA 3243
P L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH+E+V +LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I ++ L++ G +++ GN LH+A N +V ELI + +N N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ ++I+ A+++ +D + NTPLHIA R+G+E + L+ +A+ G GM P+H+A + F +C C L + TH D GR +H A AGG+L+CL ++ G D + +D +TPLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K VH+A G+ L LE++ E +D + + ND +++ + S +HLAAYHGH + L LVQ + ++ +GRT L LAA++GH V L++ GA D +H AA G + L +I + ++ + VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECV+ LL NA L D RGR ++AA+ GH +L L+ I ++ + ++ + Y TPLH+A GH C+E+L E K + LHCA+ + + E ++ ++N+ D TP+ A D++ L+ L+ HNA +N D G TP+M+AA+ G S + +L+ L DK+ LH A ++ ++ILE++ + LIN+ ++ QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA
Sbjct: 10 PPLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEDAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHVEMVSLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVTHGAEVMCKDKKSYTPLHAAASSGMISVIKYLLDLGVDMNESNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GANVNQVNERGFTPLHFAAASTHGALCLELLVCNGADVNIKSKDGKTPLHMTAIHGRFSRSQIIIQNGAEIDCEDKNGNTPLHIAARYGHELLINTLITSRADTSKRGIHGMFPLHLAALSGFSDC-CRKLLSSGFDIDTH------DDFGRTCLHAAAAGGNLECLNLLLSTGADFNKKDKFGRTPLHYAAANCNYQCLFALVGSGASVNDLDERGCSPLHYAATSDTDGKCLEYLLRNDANP----GIRD----------------KHGYNAVHYAAAYGHR----LCLELIARETPLDVLMETSGTDMLNDAETRAPI-SPLHLAAYHGHHQALEVLVQSLLD--LDVRNSTGRTPLDLAAFKGHVECVDVLINQGASILVKDYVVKRTPIHSAAINGHSECLRLLIGNADVQ---AAVDIHDGNGQTPLMLSVLNGHTECVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVEALLQHNANFLLRDCRGRTPIHLAAACGHIGVLSALLQTA---------------ISVDVVPAIADNHGY-TPLHWACYNGHDACVELLLEQEVFQKMEGNSFSPLHCAVINDNEGAAEMLIDTLGTSIVNSVDSKGRTPLHAAAFTDHIECLQLLLSHNAQVNAVDSTGKTPLMMAAENGQTSAVEVLVSSAKADLTLQDKNKNTALHLACSKGHETSALLILEQI-TDRNLINATNSALQTPLHVAARNGLTVVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILA 981
BLAST of Ankyrin repeat domain 28b vs. TrEMBL
Match: A0A2K5TKB3 (Ankyrin repeat domain 28 OS=Macaca fascicularis OX=9541 GN=ANKRD28 PE=4 SV=1) HSP 1 Score: 519.62 bits (1337), Expect = 3.545e-161 Identity = 351/1070 (32.80%), Postives = 542/1070 (50.65%), Query Frame = 1
Query: 52 MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD---VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
M I+P+L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH E+VK+LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI +I+N +N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I++ A ++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D ++PLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K+ VH++ G+ L L+++ +E +D + +++S D S D +S +HLAAYHGH + L LVQ + ++ SGRT L LAA++GH V L++ GA D +H AA+ G + L +I + + +N VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECVD LL AK L D RGR +++A+ GH +L L+ A+ + D T LH+A GH C+E+L E K+ + LHCA+ + + E ++ ++N D TP+ A D+V L+ L+ HNA +N D G TP+M+AA+ G + + +L+ + + L D S LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M
Sbjct: 1 MGIPIMPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANP----GIRD----------------KQGYNAVHYSAAYGHR----LCLQLIASETPLDVL---METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLD--LDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASM----------------DANPAIADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKI-TDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 981
BLAST of Ankyrin repeat domain 28b vs. TrEMBL
Match: A0A1D5QP01 (Ankyrin repeat domain 28 OS=Macaca mulatta OX=9544 GN=ANKRD28 PE=4 SV=2) HSP 1 Score: 519.62 bits (1337), Expect = 3.545e-161 Identity = 351/1070 (32.80%), Postives = 542/1070 (50.65%), Query Frame = 1
Query: 52 MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD---VLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
M I+P+L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH E+VK+LL +I+A DK R IHWAA G +E++ LL+ + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI +I+N +N +G T LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I++ A ++ +D + NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D ++PLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I D K+ VH++ G+ L L+++ +E +D + +++S D S D +S +HLAAYHGH + L LVQ + ++ SGRT L LAA++GH V L++ GA D +H AA+ G + L +I + + +N VD D + ++PLM++V NGHT L+ GA+VD KD +GRT+LHR GH ECVD LL AK L D RGR +++A+ GH +L L+ A+ + D T LH+A GH C+E+L E K+ + LHCA+ + + E ++ ++N D TP+ A D+V L+ L+ HNA +N D G TP+M+AA+ G + + +L+ + + L D S LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M
Sbjct: 1 MGIPIMPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC-----------------------------------GAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANP----GIRD----------------KQGYNAVHYSAAYGHR----LCLQLIASETPLDVL---METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLD--LDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNA---VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASM----------------DANPAIADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKI-TDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 981
BLAST of Ankyrin repeat domain 28b vs. Ensembl Cavefish
Match: ankrd52a (ankyrin repeat domain 52a [Source:NCBI gene;Acc:553206]) HSP 1 Score: 464.151 bits (1193), Expect = 6.264e-144 Identity = 343/1082 (31.70%), Postives = 524/1082 (48.43%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQ---TALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELI-KALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTL--------KTH-------INNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIA-NNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKL--PCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAM 3249
P L +I ++D +L+ + YDQ T LH AA++G+ +I D+LI GI V+++ + G+TPL +A AS + + +L+ GAD RD W A H+ AA+ + C +LPH+ +NI D GR ALHHA +G E+VK+LL+ S+SASDK +PIHWAA G LE+ ++ YT LH A+A GH+D+V L+ GAE+D GN ALH+A + EL+ + N +N N +G T LH+ + N C++LL+ GA+ N+ S+ GKSPLH AA + ++ +LI+ +++ D + NTPLH+A ++G+E + L+ A+ G GM P+H+A + C KLL + L K H IN DD GR +H A +GG+ +CL ++ G D++ +D +TPLH A + IL+ GA ++ D C +HY+A + L DNGA+ M N+ K PVH++ GN + LLL M N + D +S V S +HLAA GH E +N L++ S V D GR+ L++A+ +GH+ V+ LLS A + W LH AA G + L +M++S K + L + D ++PLM+AV +GH L+ GA D KD GRT+LHRA G +CV LL NA + D RGR ++AAS GH +L L++ A+ H D I H TP H+AA GH +C+E++ EL T LHCA+ + + E +L + L+NT D T + A ++V L+ ++ A+IN D G + +M+AA +G + + LLL +++D++ LH A A + C ++IL+++ P LIN+ ++ Q P H+AA N L + AL+ GA + + + P ++C N +DC+ + L+ M
Sbjct: 13 PPLVQAIFNRNAD--EVQLFCTRRMKSMHWYDQERRTPLHAAAWLGDVHIMDLLISAGI-VDAQTMCGLTPLHRAAASRNERAVGLLLRKGADVTARDKFWQTALHIAAANRATRCADTLLPHISSLNIADRTGRAALHHAAQSGCQEMVKLLLNKGASLSASDKKERQPIHWAAYLGHLEV------------VKLLRGYTPLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYMGQEAVANELVNRGAN------------------------------------VNQPNNRGYTPLHLAAVSTNGALCLELLVNNGADVNMQSKEGKSPLHMAAIHGRFTRSQILIQNGGEIDCVDRYGNTPLHVAAKYGHELLISTLMTNGADTARQGIHGMFPLHLAVLYGFSDCCRKLLSSGQLYSIVLSMSKEHVLSAGFDINTPDD--FGRTCLHAAASGGNTECLNLLLSSGADMNKKDKFGRTPLHYAAANRRYQCVVILVGAGAEVNEPDRSGCTPLHYSAASTAFCRCVEYLLDNGAD----------------PCMRNS----KGYSPVHYSAAHGNKQSLELLLVMSFN-------------TSGDAESCGPV-SPLHLAASAGHWECVNVLLE--SGMQVEVCDSVGRSVLYVASQKGHSRCVELLLSQSASCLFTEHCSRWTPLHIAAVNGHTECL-QMLISSKED--PDLPNISDTEGQTPLMLAVLDGHIDCVRLLLDQGACPDGKDRKGRTALHRAALLGWEDCVTALLSHNASVVSRDVRGRTPIHLAASCGHAEILSSLLS-AADHSHPQDPITDRHG---------------FTPAHWAAYHGHEDCLEVVLELKPCSIQEGSPFTPLHCALINGHSGSAEMLLNSSFGTSLVNTGDAKGRTVLHAAAVAEDVAGLQLILRMGAEINAVDHAGRSALMVAADKGRSAAVALLLHRAKADLSILDENKNTALHLACSKAHEMCAMLILKEIHNPV---LINATNSMLQMPLHIAARNGLATVVQALLNRGATVLAVDEEGHTPALACAPNKAVADCLALILSTM 983
BLAST of Ankyrin repeat domain 28b vs. Ensembl Cavefish
Match: ankrd44 (ankyrin repeat domain 44 [Source:ZFIN;Acc:ZDB-GENE-070912-605]) HSP 1 Score: 439.884 bits (1130), Expect = 2.311e-135 Identity = 321/1054 (30.46%), Postives = 502/1054 (47.63%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDD-------------DGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDH--LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLP 3186
P L +I D + +R ++ D+N DA +T LH AA++G++ I ++LI G VN+KD +TPL +A AS S + VLI AD N RD W HV AA+ ++ C ++I+P + +N++D GRTALHHA NGH E+V +LL +I+A DK R +HWAA G L+++ LL+D A ++ +DK YT LH A++ G I++V L+ E+D GN ALH+A N +V ELI +N Q N +G T LH + + C++ L+ GA+ N+ S +GKSPLH A + ++ LI+ +++ D NTPLHIA R+G+E + L+ A+ G GM P+H+A + C KLL + + I L + D LGR +H A AGG+++C++ ++ G D + D +TPLH A +F L+ G I+ D++ A+HYAA + + L + + L F+ + + K+ VH+A G+ + LLLE N D S +HLAAYHGH++ L L+Q + V D GRTAL LAA +GH LL+ GA P + D +H A G + L ++ + LV++ D ++PLM+AV GH L+ A VD D G T+LH G ECV LL+ A + L D +GR A ++AA+ GH + L +L++ ++ + +Q Y TPLH+A GH C+E+L E T LHCA+ + + +L+ ++++ D P+ A NV+ ++ L+ H+A ++ D +G + +M+AA+ G + + LL + +L D+ LH A + C ++ILEKLP ++ + ++ QTP HLAA + L + L++ GA + + + P
Sbjct: 10 PPLLQAIFNGDPEEIRMLIFKSEDINALDAEKRTPLHAAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLSKGANINAFDKKDGRALHWAAYMGHLDVVCLLVDQGAEVSCKDKRGYTPLHAAASNGQINVVKHLLNLSVEIDEANAFGNTALHVACFNGQDAVVSELID-----------YGANVSQP------------------------NNKGFTPLHFAAASTHGALCLEFLVNNGADVNVQSRDGKSPLHMTAVHGRFTRSQTLIQNGGEIDSVDKDGNTPLHIAARYGHELLINTLITSGADCTRRGVHGMFPLHLAALNAHADCCRKLLSSGRRYSIICPLSNDSVLCAGFQIDTPDSLGRTCLHAAAAGGNVECVKLLLSSGSDHNRTDKHGRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRSALHYAAASDLDRRRRVALEPESPGVQAEKEKEAALCLEFLLKSGATASLKDKQGYSAVHYAAAYGHRHCLELLLEREEN--------------HQDEMESSSTRSPLHLAAYHGHAQALEVLLQGHCE--VDQGDEVGRTALALAALRGHTDCALTLLNHGASPRSRDSGRGRTPIHLAVMNGHTSCVR---LLLEDSDCADLVEAADSQGQTPLMLAVVGGHVDAVSLLLEREASVDTADHQGLTALHLGLLCGQEECVQCLLEQEASVLLGDSKGRTALHLAAARGHASWLSELLSIACSE---------------PPTPPLRDNQGY-TPLHWACYNGHEGCVEVLLEQKGCRCFDGNPFTPLHCAVVNDHESCATLLLEAMGSEIVTCKDSRDRAPLHAAAFAGNVDCVQLLLAHDAPVDAVDQSGRSALMMAAERGAVGVVEALLTSASADLSLTDQKGNTALHLACSKGKEDCALLILEKLP-DTTIVKATNSALQTPLHLAAHSGLKQTVKELLSRGASVQVLDENGVCP 992 HSP 2 Score: 120.939 bits (302), Expect = 3.072e-27 Identity = 143/550 (26.00%), Postives = 228/550 (41.45%), Query Frame = 1
Query: 1477 QTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMK-LINYVANKYHQ--------------GDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDE--MKSTNGFMTFLHCAIDSKCD---------ETLECVLKIANNDL------INTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILE 3030
Q PL A+ + R+LI I+ D +H AA + +I+ LL +GA + N DN L P+H AV S + + + +L+ + V++ ++Q+ +H+AA + ++ + S V+ DR GRTALH AA GH V LLS GA A DK ALH+AA G +D + ++ ++ + V D+ +PL A NG + L+ ++D + +G T+LH A NG V L+D A + + +G + AA++ H L ++ L+N A+ Q G F +S + N + D+D TPLH AA GH I L + + +G A+++ D + ++N+ + I+TPD T + A NV ++ L+ +D N D +G TP+ AA CL L+ C T A D+ ++ LHYA S D + LE
Sbjct: 9 QPPLLQAIFNGDPEEIRMLIFKSEDINALDAEKRTPLHAAAFLG-DAEIIELLILSGARV---------------NAKDNMWL-----TPLHRAVASRSEEAVRVLIRHSAD----------VNARDKNWQTP------LHVAAANKALRCAEVIIPLLSS--VNVSDRGGRTALHHAALNGHTEMVSLLLSKGANINAFDKKD-GRALHWAAYMGHLDVVCLLV------DQGAEVSCKDKRGYTPLHAAASNGQINVVKHLLNLSVEIDEANAFGNTALHVACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNNGADVNVQSRDGKSPLHMTAVHGRFT-RSQTLIQNGGEIDSVDKDGNTPLHIAARYGHELLINTLITSGADCTRRGVHGMFPLHLAALNAHADCCRKLLSSGRRYSIICPLSNDSVLCAGFQIDTPDSLGRTCLHAAAAGGNVECVKLLLSSGSDHNRTDKHGRTPLHYAAASRHFQCLETLVSCGTCINA-TDQWGRSALHYAAASDLDRRRRVALE 510 HSP 3 Score: 64.6994 bits (156), Expect = 6.465e-10 Identity = 77/343 (22.45%), Postives = 131/343 (38.19%), Query Frame = 1
Query: 2209 RSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMK-STNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEI 3234
+ PL+ A+ NG LI D++ D RT LH A G E ++LL+ A++ D L L VA++ + + H +N D+++ TPLH AA+ C E++ L + S G T LH A + E + +L N IN DK + +A + +++ + L+ A+++ +D G TP+ AA G ++ + LL L I+ + T H+A FN ++ LI +GA++ N K P+ ++ + C+E
Sbjct: 9 QPPLLQAIFNGDPEEIRMLIFKSEDINALDAEKRTPLHAAAFLGDAEIIELLILSGARVNAKD---------------NMWLTPLHRAVASRSEEAVRVLIRHSADVNA-----RDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLSKGAN--INAFDKKDGRALHWAAYMGHLDVVCLLVDQGAEVSCKDKRGYTPLHAAASNGQINVVKHLLN--------------------------------------LSVEIDEANAFGNTALHVACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEF 291
BLAST of Ankyrin repeat domain 28b vs. Ensembl Cavefish
Match: ANKRD52 (ankyrin repeat domain 52 [Source:HGNC Symbol;Acc:HGNC:26614]) HSP 1 Score: 401.749 bits (1031), Expect = 2.951e-121 Identity = 334/1122 (29.77%), Postives = 520/1122 (46.35%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELI-KALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDD-------------DGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAA---MYNKEGDI----------------LRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLA-AYHGHSEILNYL---VQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSD-EMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAM--FSSTDSPANLALKTSLNLSPKKGYVINLKEAELEGSIQSS 3369
L+ DVN D +T LH AA +G+ I D+LIK G VN+KD +TPL +A AS + + +L+ GA+ + RD W HV AA+ ++ C + ++P + +N+ D +GRTALHHA +GH E+V +LL+ ++SASDK + IHWAA G LEI+ +L+ +A++ RDK YT LH+A+ GHID+V L+ GAE+D GN +LH+A N + EL+ + N +N N +G T LH+ + N C++LL+ GA+ N+ S+ GKSPLH AA + ++ +LI+ +++ D + NTPLHIA + G+E + L+ A+ G GM P+H+A + C KLL + L + +++L + D LGR +H A +GG+++CL ++ G D+ +D L + PLH A F T L+ GA+++ D C +HYAA + + G I L L DNGA E + +N K PVH+A GN + LLLEM +C+ G V+SS +S +HLA + +ILN +++ S+ +VS R G L LA H V LL G+KP DK + ALH AA GS D V +L EH+ S L +D G++ LH A + GH E + LLL A+ + D L++Y G + S P H+ H +C+E++ E ++ N F T LHCA+ + D E +++ +++IN D TP+ A H + V+ L+ ++ +++N D +G + +M+AA+ G + + +LL +L+D +N LH A + C ++IL ++ L LIN+ +N Q P H+AA N L + L++ GA + + + P ++C N +DC+ + L+ M F S D A SLNL G +I + GS++ S
Sbjct: 16 LHKNDDVNALDQERRTPLHAAACLGDVRIMDLLIKSGASVNAKDQGWLTPLHRAAASRNERAVGLLLRQGAEVSARDRLWQTPLHVAAANRAMRCAEALVPLLSSLNVADRNGRTALHHAAYSGHTEMVTLLLNKGANLSASDKKDRQAIHWAAYLGHLEIVKVLVSRNADVACRDKRGYTPLHVAAINGHIDVVKYLLRLGAEIDEPNAFGNTSLHMACYNGQEAVANELVNRGAN------------------------------------VNQPNLRGCTPLHLAAVSTNGALCLELLVNNGADVNMQSKEGKSPLHMAAIHGRFTRSQILIQNGGEIDCVDKYGNTPLHIAAKHGHELLISTLMTNGADTARQGIHGMFPLHLAVLYGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDSLGRTCLHAAASGGNVECLNLLLSSGADLTKKDKLGRAPLHYAAANGTFQCTVALVSAGAAVNELDLKGCSPLHYAAASQTFRRYGTIGEDLSVSQRSAFVFRCLEYLLDNGA---------------EPGLRNN-----KGFSPVHYAAAYGNKQNLELLLEM-----SFNCL-GDVESSFP--------VSPLHLAVSITVLIKILNMFYISLRVLSETLVSLDVRDGGGPLMLATLGSHVDCVHMLLERGSKPDTGDK-WSRTALHRAAVVGSEDC----------------VSALLEHEASGLC-----------------------RDVRGKSPLHLAASCGHGEVLRLLLQAAAQSDPLD--------------------SLLDY------SGYTLATS-------------------PHHWEDGWRHKDCLEVILEHKPLSIQEGNSF-TPLHCALMNGHDAAAELMVETMGSEIINLRDAKGRTPLHAAAHSEKVSGLQLALVWGSEVNSVDYSGRSALMVAAETGQTTAVEILLHQAKADLSLLDMNNNTALHLACSRGHEMCALLILSEIDDL-SLINATNNALQMPLHIAARNGLATVVEVLLSRGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKPFPSKDPTAGATY--SLNLLKHCG-IIATRHPLPNGSLRHS 977 HSP 2 Score: 134.806 bits (338), Expect = 1.536e-31 Identity = 199/855 (23.27%), Postives = 353/855 (41.29%), Query Frame = 1
Query: 1090 SRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPIN---INDHLSFI-----------ENNIMDNTSL------GKKIV-------------------YPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSL-DEH--------------KRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFI-NELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELS----DEMKSTNGFMTFLHCAIDSKC---------------DETL---------------------ECV-LKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLK---WALVDKSNQNIL----HYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALI-TFGADLY-LKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKG 3318
S +++ L+ DVN D TPLH A G + + +L++ A+ + + P+H A A +N + + L+ D L + +H A A +++C E ++ L ++ D +T LH A + + +L+ GA++ D+ AIH+AA Y +I+++L A++ +P++ IN H+ + E N NTSL G++ V P+H A +S N L LE++ N + + + QSK+ S +H+AA HG L+Q + + D+ G T LH+AA GH + + L++ GA TA + LH A G D +++ S +L S+V SL +EH R+ L A G+ L+ +GAD+ KD GR LH A ANG +C L+ A + D +G + + AA A I + + F+ + + + N + + +P+H+AA+ G+ +E+L E+S +++S+ ++ LH A+ ETL +CV + + +T DK+S T + A + + + L+ H A +DV G +P+ +AA G L LLL+ +L+D S + H+ C +ILE P ++ + N TP H A N ++ T G+++ L++ K + P+ + + K S + LA ++ S + + + +++L ++ + G
Sbjct: 5 SLRNVEEVKFLLHKNDDVNALDQERRTPLHAAACLGDVRIMDLLIKSGASVNAKDQGWLTPLHRAAASRN-----ERAVGLLLRQGAEVSARDRLWQTPLHVAAANRAMRCAEALVPLLSSLNVADRNGRTALHHAAYSGHTEMVTLLLNKGANLSASDKKDRQAIHWAA-YLGHLEIVKVLVSRNADVACRDKRGYTPLHVAAINGHIDVVKYLLRLGAEIDEPNAFGNTSLHMACYNGQEAVANELVNRGANVNQPNLRGCTPLHLAAVSTNG---ALCLELLVN-----------NGADVNMQSKEGK-SPLHMAAIHGRFTRSQILIQ--NGGEIDCVDKYGNTPLHIAAKHGHELLISTLMTNGAD-TARQGIHGMFPLHLAVLYGFSDCCRKLLSSGQL---YSIVSSLSNEHVLSAGFDINTPDSLGRTCLHAAASGGNVECLNLLLSSGADLTKKDKLGRAPLHYAAANGTFQCTVALVSAGAAVNELDLKGCSPLHYAA-ASQTFRRYGTIGEDLSVSQRSAFVFRCLEYLLDNGAEPGLRNNKGFSPVHYAAAYGNKQNLELLLEMSFNCLGDVESSFP-VSPLHLAVSITVLIKILNMFYISLRVLSETLVSLDVRDGGGPLMLATLGSHVDCVHMLLERGSKPDTGDKWSRTALHRAAVVGSEDCVSALLEHEASGLCRDVRGKSPLHLAASCGHGEVLRLLLQAAAQSDPLDSLLDYSGYTLATSPHHWEDGWRHKDCLEVILEHKP-----LSIQEGNSFTPLHCALMNGHDAAAELMVETMGSEIINLRDAKGRTPLHAAAHSEKVSG---LQLALVWGSEVNSVDYSGRSALMVAAETG 822
BLAST of Ankyrin repeat domain 28b vs. Ensembl Cavefish
Match: ankrd44 (ankyrin repeat domain 44 [Source:ZFIN;Acc:ZDB-GENE-070912-605]) HSP 1 Score: 365.155 bits (936), Expect = 1.805e-108 Identity = 296/969 (30.55%), Postives = 448/969 (46.23%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAF-VAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLK------QTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYN----------KEGDI-LRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVY-PVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNL 2919
P L +I D + +R ++ D+N DA +T LH AA++G++ I ++LI G VN+KD +TPL +A AS S + VLI AD N RD W HV AA+ ++ C ++I+P + +N++D GRTALHHA NGH E+V +LL +I+A DK R +HWAA G L+++ LL+D A ++ +DK YT LH A++ G I++V L+ E+D GN ALH+A N +V ELI +N Q N +G T LH + + C++ L+ GA+ N+ S +GKSPLH A + ++ LI+ +++ D NTPLHIA R+G+E + L+ A+ G GM P+H+A + C KLL + I+ D LGR +H A AG + + L + + + + +TPLH A +F L+ G I+ D++ A+HYAA + KE + L L +GA SL K Y VH+A G+ + LLLE N D S +HLAAYHGH++ L L+Q + V D GRTAL LAA +GH LL+ GA P + D +H A G + L ++ + LV++ D ++PLM+AV GH L+ A VD D G T+LH G ECV LL+ A + L D +GR A ++AA+ GH + L +L++ ++ + +Q Y TPLH+A GH C+E+L E T LHCA+ + + +NT + P+ A NV+ ++ L+ H+A ++ D +G + +M+AA+ G + + +
Sbjct: 6 PPLLQAIFNGDPEEIRMLIFKSEDINALDAEKRTPLHAAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLSKGANINAFDKKDGRALHWAAYMGHLDVVCLLVDQGAEVSCKDKRGYTPLHAAASNGQINVVKHLLNLSVEIDEANAFGNTALHVACFNGQDAVVSELID-----------YGANVSQP------------------------NNKGFTPLHFAAASTHGALCLEFLVNNGADVNVQSRDGKSPLHMTAVHGRFTRSQTLIQNGGEIDSVDKDGNTPLHIAARYGHELLINTLITSGADCTRCVGVHGMFPLHLAALNAHADCCRKLLSS---GFQIDT--PDSLGRTCLH-AAAGSADRLLCVCVCVCVCMCVCMGVCAYIHDYRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRSALHYAAASDLDRRLQAEKEKEAALCLEFLLKSGAT---------------------ASLKDKQGYSAVHYAAAYGHRHCLELLLEREEN--------------HQDEMESSSTRSPLHLAAYHGHAQALEVLLQGHCE--VDQGDEVGRTALALAALRGHTDCALTLLNHGASPRSRDSGRGRTPIHLAVMNGHTSCVR---LLLEDSDCADLVEAADSQGQTPLMLAVVGGHVDAVSLLLEREASVDTADHQGLTALHLGLLCGQEECVQCLLEQEASVLLGDSKGRTALHLAAARGHASWLSELLSIACSE---------------PPTPPLRDNQGY-TPLHWACYNGHEGCVEVLLEQKGCRCFDGNPFTPLHCAV--------YVFFSVEKSGKMNTDVIFCRAPLHAAAFAGNVDCVQLLLAHDAPVDAVDQSGRSALMMAAERGAVGVVGM 869 HSP 2 Score: 151.369 bits (381), Expect = 1.205e-36 Identity = 199/773 (25.74%), Postives = 321/773 (41.53%), Query Frame = 1
Query: 940 LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPIN----------INDH----LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHK-RSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANG-----HVE-------CVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHD------------------IFINELKSMWFDQDYLTPLHFAASRGHTNCIEML--YELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIAN-NDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQ-TPAHLAAFNS 3111
+N+ + + T LH + + +A + ++LL+ GA N +PLH A + + +LI+ ADVN +D + TPLH+A + ++++ ++ V+ G +H A A M LL ++ +IN D GR L H A G L + ++ G ++ +D TPLH A + + L+ L ID + + A+H A +N + ++ L D GAN+ P N + H L F+ NN D + P+H + G F L++ G +DS D + +H+AA +GH ++N L+ + G LHLAA HA + LLS G + D LH AA GS D L + + V + + H R+PL A + H + E L+ G ++ D +GR++LH A A+ E C++ LL A L D +G +A + AA+ GH++ L L+ N HQ D +E S + + D+ T L AA RGHT+C L + S + + T +H A+ + + +L+ ++ DL+ D TP+ AV +V+A+ L+ A ++ D G T + + G C+ LLE Q L D + LH A S + L + C + L +NQ TP H A +N
Sbjct: 30 INALDAEKRTPLHAAAFLGDA-EIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHA-ALNGHTEMVSLL--LSKGANINAFDKKD-GRAL-HWAAYMGHLDVVCLLVDQGAEVSCKDKRGYTPLHAAASNGQINVVKHLLNLSVEIDEANAFGNTALHVAC-FNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNNGADVNVQSRDGKSPLHMTAVHGRFTRSQTLIQN----------GGEIDSVDKDGNTP------LHIAARYGHELLINTLI-TSGADCTRCVGVHGMFPLHLAALNAHADCCRKLLSSGFQIDTPDS-LGRTCLHAAA--GSADRLLCVCVCVCVCMCVCMGVCAYIHDYRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRSALHYAAASDLDRRLQAEKEKEAALCLEFLLKSGATASLKDKQGYSAVHYAAAYGHRHCLELLLEREEN--HQ-DEMESSSTRSPLHLAAYHGHAQALEVLLQGHCEVDQGDEVGRTALALAALRGHTDCALTLLNHGASPRSRDSGRGRTPIHLAVMNGHTSCVRLLLEDSDCADLVEAADSQGQTPLMLAVVGGHVDAVSLLLEREASVDTADHQGLTALHLGLLCGQEECVQCLLE-QEASVLLGDSKGRTALHLAAARGHAS-WLSELLSIACSEPPTPPLRDNQGYTPLHWACYNG 770 HSP 3 Score: 134.806 bits (338), Expect = 1.436e-31 Identity = 175/689 (25.40%), Postives = 290/689 (42.09%), Query Frame = 1
Query: 1060 NGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGML--PIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSP---------ININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEI-LNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYG--------------------------------------RTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQG----DFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYEL----SDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVN-GCTPIMIAAKEGTLSCLNLLLE 2928
+ K PL A ++ +LI D+N D + TPLH A G + +++L+ + A V +D M P+H A A ++ + L+ + +N D + + +H A A +L+C E II L ++ D +T LH A + + +L+ GA+I+ D+ A+H+AA Y D++ LL D GA + +P IN+ HL + I + + G +H A +G D ++ L +D N Q + + +H AA H + L +LV + V+ Q R G++ LH+ A G + L+ G + +VDKD LH AA G +E++++ + + + H PL +A N H KL+ +G +D D+ G RT LH A A+ H +C++ L+ C I D GR+A + AA++ L A K + +F+ KS S+ Q Y + +H+AA+ GH +C+E+L E DEM+S++ + LH A + LE +L+ + ++ D+ T + A + + L+ H A +D G TPI +A G SC+ LLLE
Sbjct: 3 DAKPPLLQAIFNGDPEEIRMLIFKSEDINALDAEKRTPLHAAAFLGDAEIIELLI--LSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRH---SADVNARDKN--WQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLSKGANINAFDKKDGRALHWAA-YMGHLDVVCLLVDQGAEVSCKDKRGYTPLHAAASNGQINVVKHLLNLSVEIDEANAFGNTA---LHVACFNGQ-DAVVSEL---------------IDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNNGAD--VNVQSRDGKSPLHMTAVHGRFTRSQTLIQNGGEIDSVDKDGN-TPLHIAARYG-----HELLINTLITSGADCTRCVGVHGMFPLHLAALNAHADCCRKLLSSGFQIDTPDSLGRTCLHAAAGSADRLLCVCVCVCVCMCVCMGVCAYIHDYRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRSALHYAAASDLDRRLQ------AEKEKEAALCLEFLLKS-----GATASLKDKQGY-SAVHYAAAYGHRHCLELLLEREENHQDEMESSS-TRSPLHLAAYHGHAQALEVLLQ--GHCEVDQGDEVGRTALALAALRGHTDCALTLLNHGASPRSRDSGRGRTPIHLAVMNGHTSCVRLLLE 641 HSP 4 Score: 84.7297 bits (208), Expect = 4.091e-16 Identity = 135/506 (26.68%), Postives = 210/506 (41.50%), Query Frame = 1
Query: 268 TPLFKACASNSHNVLTVLISSGADTNCRDNKWNR-AFHVCAAHN------------SVDCLKLILPHVLGINITDSDGRTALHHAVANGH--IEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCV-TTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHF---VLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIK----AKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKA------NAFVA-----------GEDGML---------PIHVATAFKNCGCMHKLLDNVTLKTHINNLDD-DGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDN---------------LKQ-------TPLHLAVKLNNFMITRILIKLGASIDVEDE 1569
TPL A AS L L+S G N D +W R A H AA + + CL+ +L ++ D G +A+H+A A GH + + + N + P+H AA G + L +LL ++ D+ TAL +A+ GH D + L+ GA + +G +HLA N HT+ V L++ + + L +E S L+ + H L+ ER E+ +++ ++QGLT+LH L + +CV LL A+ L G++ LH AA+R L+ ++D+ TPLH AC G+E V++LLE K N F + G + P+H A N C+ LL H +D D GR+ + A G++ + G +I+H+ + LK +PLHLA + L+ GAS+ V DE
Sbjct: 442 TPLHYAAASRHFQCLETLVSCGTCINATD-QWGRSALHYAAASDLDRRLQAEKEKEAALCLEFLLKSGATASLKDKQGYSAVHYAAAYGHRHCLELLLEREENHQDEMESSSTRSPLHLAAYHGHAQALEVLLQGHCEVDQGDEVGRTALALAALRGHTDCALTLLNHGASPRSRDSGRGRTPIHLAVMNGHTSCVRLLLEDSDCADL-VEAADSQGQTPLMLAVVGGHVDAVSLLLER-EASVDTADHQGLTALH-LGLLCGQEECVQCLLEQEASVLLGDSKGRTALHLAAARGHASWLSELLSIACSEPPTPPLRDNQGYTPLHWACYNGHEGCVEVLLEQKGCRCFDGNPFTPLHCAVYVFFSVEKSGKMNTDVIFCRAPLHAAAFAGNVDCVQLLL------AHDAPVDAVDQSGRSALMMAAERGAVGVV------GMNINHQPHIIYLLTVNPGGENCILKSFVMFIYFSPLHLAAHSGLKQTVKELLSRGASVQVLDE 931 HSP 5 Score: 65.4698 bits (158), Expect = 3.404e-10 Identity = 77/343 (22.45%), Postives = 131/343 (38.19%), Query Frame = 1
Query: 2209 RSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMK-STNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEI 3234
+ PL+ A+ NG LI D++ D RT LH A G E ++LL+ A++ D L L VA++ + + H +N D+++ TPLH AA+ C E++ L + S G T LH A + E + +L N IN DK + +A + +++ + L+ A+++ +D G TP+ AA G ++ + LL L I+ + T H+A FN ++ LI +GA++ N K P+ ++ + C+E
Sbjct: 5 KPPLLQAIFNGDPEEIRMLIFKSEDINALDAEKRTPLHAAAFLGDAEIIELLILSGARVNAKD---------------NMWLTPLHRAVASRSEEAVRVLIRHSADVNAR-----DKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLSKGAN--INAFDKKDGRALHWAAYMGHLDVVCLLVDQGAEVSCKDKRGYTPLHAAASNGQINVVKHLLN--------------------------------------LSVEIDEANAFGNTALHVACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEF 287 HSP 6 Score: 53.9138 bits (128), Expect = 1.378e-6 Identity = 56/219 (25.57%), Postives = 94/219 (42.92%), Query Frame = 1
Query: 2560 DYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGF-MTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSK 3213
D PL A G I ML S+++ + + T LH A E +E L I + +N D TP+ AV + A+ LI H+AD+N +D N TP+ +AA L C +++ + + D+ + LH+A + ++L K IN+ D H AA+ + L+ GA++ K+ + P+ + N +
Sbjct: 3 DAKPPLLQAIFNGDPEEIRMLIFKSEDINALDAEKRTPLHAAAFLGDAEIIE--LLILSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLS-SVNVSDRGGRTALHHAALNGHTEMVSLLLSK----GANINAFDKKDGRALHWAAYMGHLDVVCLLVDQGAEVSCKDKRGYTPLHAAASNGQ 214
BLAST of Ankyrin repeat domain 28b vs. Ensembl Cavefish
Match: ANKRD28 (ankyrin repeat domain 28 [Source:HGNC Symbol;Acc:HGNC:29024]) HSP 1 Score: 347.436 bits (890), Expect = 1.313e-102 Identity = 279/928 (30.06%), Postives = 432/928 (46.55%), Query Frame = 1
Query: 505 VVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDD---VLSLIHLAAYHGHSEILNYLVQ-IFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPAN 3276
+VK+LL +I+A DK R IHWAA G +E++ LL+ + + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI+A + +N N +G LH + C++LL+ GA+ N+ S++GK+PLH AA + ++ +I++ A+++ +D + N+PLHIA R+G+E + L+ AN G GM P+H+A C KLL + ++ DD GR SL C + I L TPLH A N+ L+ GAS++ D C +HYAA + + L L N AN I D K+ VH+A G+ L LE++ +E +D + +++S D + D +S +HLAAYHGH L LVQ + ++ + Q G T L LAA++GH V L++ GA D +H AA G ++ L +I + + + VD D ++PLM+AV NGHT L+ GA V+ KD +GRT+LHR GH CV+ LL +A + + D RGR A ++AA+ GH + +N V + D TPLH+A GH C+E L E K + LHCA+ S + E ++ ++N D S TP+ A + D+V L+ L+ HNA +N D G TP+M+AA+ G + + +L+ L D + + LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M + A
Sbjct: 1 MVKLLLSRGANINAFDKKDRRAIHWAAYMGHMEVVRLLVSHGTEVTCKDKKAYTPLHAAASSGMISVVKYLLDLGVDINEPNAYGNTPLHVACYNGQDVVVNELIEA-----------------------------------GANVNQVNEKGFAPLHFTAASRQGALCLELLVGNGADVNIKSKDGKTPLHMAAIHGRFSRSQAVIQSGAEIDCEDKNGNSPLHIAARYGHELLINTLITNGANTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDVDTPDD--FGRT---------SLLCSDWSIFF---------LSLTPLHYAAANCNYQCLFALVGSGASVNDMDVRGCTPLHYAAASDTDAKCLEYLLRNDAN----PGIRD----------------KQGYNAVHYASAYGHR----LCLELITSETPLDVL---METSGTDILNDTDGQTPISPLHLAAYHGHHPALEVLVQSLLDLDVRTVQ---GHTPLDLAAFKGHVECVDVLITQGASILLKDYSQKRTPIHAAAMNGHLECLRLLIGNA---DPHAAVDVQDGSGQTPLMLAVLNGHTDCVYFLLSKGASVEAKDKWGRTALHRGAVTGHEACVEALLQHSASLPVRDSRGRTAMHLAAACGH----IGSLNTV----------------------PVIMDNCGYTPLHWACYNGHDTCVEALLEQEVFHKMEGNSFSPLHCAVISDNEGAAELLIDTLGPAIVNATDSKSRTPLHAAAYTDHVECLQLLLGHNAQVNAIDALGKTPLMMAAENGQTNAVEVLVSRAKADLTLQDANKNSALHLACSKGHETSALLILEKV-SDRNLINATNAALQTPLHVAARNGLTVVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMMPVSPGSAG 810 HSP 2 Score: 171.785 bits (434), Expect = 3.261e-43 Identity = 236/934 (25.27%), Postives = 382/934 (40.90%), Query Frame = 1
Query: 217 ILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHW-AAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGK---------------SPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYE-KFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLD----NVTLKTHINNLDDDGLGRNLV---HCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVED-EYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQG---SVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLI--MNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLS-CLNLLL 2925
+L+ G ++N+ D + A V+ +L+S G + C+D K H A+ + +K +L + IN ++ G T LH A NG VV L++ +++ ++ G P+H+ AA+R L LL+ N A++NI+ KD T LH+A+ G +I+ GAE+DC G NS L H+ LI + N K R G+ LH L+ + C LL+ G + + + G+ +PLH+AA+ + L+ + A VN D TPLH A + K ++ LL AN + + G +H A+A+ + C+ + +V ++T ++ +D G+ + H A G LE +++ D+ TPL LA + +LI GASI ++D IH AAM N + LRLL N A+ + +++ D G+ P+ AV++G+ D + LL KG +++ + + +H A GH + L+Q + + +D GRTA+HLAA GH + S P +D Y LH+A G V+AL E + K+E + SPL AV + + AE LI + A V+ D+ RT LH A HVEC+ LLL NA++ D G+ MAA G N + L++ + D + D + + LH A S+GH ++ E K+++ +LIN + TP+ A + +++L+ A + D NG TP + A ++ CL L+L
Sbjct: 4 LLLSRGANINAFDKKDRRAIHWAAYMGHMEVVRLLVSHGTEVTCKDKKAYTPLHAAASSGMISVVKYLLDLGVDINEPNAYGNTPLHVACYNGQDVVVNELIEAGANVNQVNEKGFAPLHFTAASRQGALCLELLVGNGADVNIKSKDGKTPLHMAAIHGRFSRSQAVIQSGAEIDCEDKNG-----------------------NSP---LHIAARYGHELLINTLITNGANTAK---------RGIHGMFPLH-LAALSGFSDCCRKLLSSGFDVDTPDDFGRTSLLCSDWSIFFLSLTPLHYAAANCNYQCLFALVGSGASVNDMDVRGCTPLHYAAASDTDAKCLEYLLRNDANPGIRDKQGYNAVHYASAYGHRLCLELITSETPLDVLMETSGTDILNDTDGQTPISPLHLAAYHGHHPALEVLVQSLLDLDVRTVQGHTPLDLAAFKGHVECVDVLITQGASILLKDYSQKRTPIHAAAM-NGHLECLRLLIGN-ADPHAAVDVQD-------------GSGQT---PLMLAVLNGHTDCVYFLLS-----------KGASVEAKDKWGR-----TALHRGAVTGHEACVEALLQHSAS--LPVRDSRGRTAMHLAAACGH------IGSLNTVPVIMDNCGY-TPLHWACYNGHDTCVEALLEQEVFHKMEG----------NSFSPLHCAVISDNEGAAELLIDTLGPAIVNATDSKSRTPLHAAAYTDHVECLQLLLGHNAQVNAIDALGKTPLMMAAENGQTNAVEVLVSRA-----KADLTLQ--------------DANKNSALHLACSKGHETSALLILE-------------------------------KVSDRNLINATNAALQTPLHVAARNGLTVVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALIL 798 HSP 3 Score: 149.058 bits (375), Expect = 5.421e-36 Identity = 200/827 (24.18%), Postives = 331/827 (40.02%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVD-----------------------------------CLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEEL-IKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAAS----------RNQLKQAVLLIKAKADVNIQDDHEN--TPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHH----EDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLF---------DNGANILSPININDHLSFIEN--NIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYG---RTSLHRATANGHVECVDLLLDCNAKIELFDFRG 2406
L ++N D D+ A+H AAY+G+ + +L+ +G +V KD TPL A +S +V+ L+ G D N + N HV A +N D CL+L++ + +NI DG+T LH A +G + ++ + I DKNG P+H AA G ++N L+ N AN R LH+A+ G D +L+ G ++D G +L + + + L A N ++ L F L+ + +N + +G T LH + D +C++ LL ANP + + G + +H+A++ ++ VL+ + D+ D + +PLH+A G+ +++L++ + V G P+ +A + C+ L +T I L D R +H A G L+CL +I D H +D QTPL LAV + L+ GAS++ +D++ A+H A+ E + LL G + H+ + IMDN P+H+A +G+ + LLE + ++ + + S +H A + L+ IV+ D RT LH AAY H ++ LL A+ A+D L AA G +A+ ++ K + + D +K S L +A GH +A ++ +D +L + +T LH A NG V LL A + D G
Sbjct: 6 LSRGANINAFDKKDRRAIHWAAYMGHMEVVRLLVSHGTEVTCKDKKAYTPLHAAASSGMISVVKYLLDLGVDINEPNAYGNTPLHV-ACYNGQDVVVNELIEAGANVNQVNEKGFAPLHFTAASRQGALCLELLVGNGADVNIKSKDGKTPLHMAAIHGRFSRSQAVIQSGAEIDCEDKNGNSPLHIAARYGHELLINTLITNGANTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDVDTPDDFGRTSLLCSDWSIFFLSLTPLHYAAANCNYQCL-------------------FALVGSG--ASVNDMDVRGCTPLHYAAASDTDAKCLEYLLRNDANPGIRDKQGYNAVHYASAYGHRLCLELITSETPLDVLMETSGTDILNDTDGQTPISPLHLAAYHGHHPALEVLVQSLLDLDVRTVQGHTPLDLAAFKGHVECVDVL---ITQGASI-LLKDYSQKRTPIHAAAMNGHLECLRLLIG-NADPHAAVDVQDGSGQTPLMLAVLNGHTDCVYFLLSKGASVEAKDKWGRTALHRGAVTGHEACVEALLQHSASLPVRDSRGRTAMHLAAACGHIGSLNTVPVIMDNCGY-----TPLHWACYNGHDTCVEALLEQ-----------------EVFHKMEGNSFSPLHCAVISDNEGAAELLIDTLGPAIVNATDSKSRTPLHAAAYTDHVECLQLLLGHNAQVNAIDA-LGKTPLMMAAENGQTNAVEVLVSRAKAD-----LTLQDANKNSALHLACSKGHETSALLILEKVSDRNLINATNAALQTPLHVAARNGLTVVVQELLGKGASVLAVDENG 777 HSP 4 Score: 144.821 bits (364), Expect = 1.055e-34 Identity = 203/720 (28.19%), Postives = 312/720 (43.33%), Query Frame = 1
Query: 130 NKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTA---------------LHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXX-XXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGK-SPLHFAASRNQLKQAVLLIK---AKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLD-DDGLGRNLVHCAVAGGSLKCLETIIRL---------------GGDIHHEDNLKQ-----------TPLHLAVKLNNFMITRILI-KLGASI-DVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGH-SEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDAL 2139
N DVNIK +T LH+AA G + + +I+ G +++ +D NG +PL A ++ LI++GA+T R H+ A DC + +L ++ D GRT+ LH+A AN + + + L+ + S++ D G P+H+AAA L LL NDAN IRDK Y A+H ASA GH + + LI LD V + + L + T I + A + H LE VL++ L+ L+ R QG T L L+ +CVD+L+ GA+ L + K +P+H AA L+ LLI A V++QD TPL +A G+ V LL A+ + G +H + C+ LL H +L D GR +H A A G + L T+ + G D E L+Q +PLH AV +N +LI LG +I + D + +H AA Y + L+LL + A + N +D +LGK P+ A +G + + E++ + AK D D+++N S +HLA GH + L L ++ +N+++ + + +T LH+AA G + V+ LL GA AVD++ Y AL A ++ D L
Sbjct: 141 NGADVNIKSKDGKTPLHMAAIHGRFSRSQAVIQSGAEIDCEDKNGNSPLHIAARYGHELLINTLITNGANTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDVDTPDDFGRTSLLCSDWSIFFLSLTPLHYAAANCNYQCLFALVGSGASVNDMDVRGCTPLHYAAASDTDAKCLEYLLRNDANPGIRDKQGYNAVHYASAYGH-RLCLELITSETPLD-VLMETSGTDILNDTDGQTPISPLHLAAYHGHHPALE-------------------VLVQSLLD--LDVRTVQGHTPLD-LAAFKGHVECVDVLITQGASILLKDYSQKRTPIHAAAMNGHLECLRLLIGNADPHAAVDVQDGSGQTPLMLAVLNGHTDCVYFLLSKGASVEAKDKWGRTALHRGAVTGHEACVEALLQ------HSASLPVRDSRGRTAMHLAAACGHIGSLNTVPVIMDNCGYTPLHWACYNGHDTCVEALLEQEVFHKMEGNSFSPLHCAVISDNEGAAELLIDTLGPAIVNATDSKSRTPLH-AAAYTDHVECLQLLLGHNAQV---------------NAID--ALGKT---PLMMAAENGQTNAV----EVLVSRAKADLTL--QDANKN---------SALHLACSKGHETSALLILEKVSDRNLINATNAALQTPLHVAARNGLTVVVQELLGKGASVLAVDENGYTPALACAPNKDVADCL 794 HSP 5 Score: 114.005 bits (284), Expect = 3.615e-25 Identity = 143/539 (26.53%), Postives = 213/539 (39.52%), Query Frame = 1
Query: 1858 NDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGA---KPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPL-MIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGF-MTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGT-LSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLP-----------------------------------CLKKLINSLDN------NQQTPAHLAAFNSLPLFLNALITFGADLYLKNF-KSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGYVIN 3330
N + KD IH AAY GH E++ LV ++ V+ +D+ T LH AA G VK+LL G +P A Y LH A G +NE+I + V+ ++E +PL A E L+ NGADV++K G+T LH A +G ++ A+I+ D G + ++AA GH+ L+ LI AN +G H +F PLH AA G ++C L ++ + + F T L C+ D ++ + S TP+ YA + N L L+ A +N DV GCTP+ AA T CL LL + DK N +HYA C +I + P L+ L+ SL + TP LAAF ++ LIT GA + LK++ + + PI + N CL + + D A + ++ +P V+N
Sbjct: 13 NAFDKKDR--RAIHWAAYMGHMEVVRLLVSHGTE--VTCKDKKAYTPLHAAASSGMISVVKYLLDLGVDINEPNA----YGNTPLHVACYNGQDVVVNELI------EAGANVNQVNEKGFAPLHFTAASRQGALCLELLVGNGADVNIKSKDGKTPLHMAAIHGRFSRSQAVIQSGAEIDCEDKNGNSPLHIAARYGHELLINTLITNGANTAKRG-----IHGMF---------------PLHLAALSGFSDCCRKLLSSGFDVDTPDDFGRTSLLCS-----DWSIFFL---------------SLTPLHYAAANCNYQCLFALVGSGASVNDMDVRGCTPLHYAAASDTDAKCLEYLLR-NDANPGIRDKQGYNAVHYASAYGHRLCLELITSETPLDVLMETSGTDILNDTDGQTPISPLHLAAYHGHHPALEVLVQSLLDLDVRTVQGHTPLDLAAFKGHVECVDVLITQGASILLKDYSQKRTPIHAAAMNGHLE-----CLRLLIGNADPHAAVDVQDGSGQTPLMLAVLN 491 HSP 6 Score: 70.4774 bits (171), Expect = 1.046e-11 Identity = 89/335 (26.57%), Postives = 145/335 (43.28%), Query Frame = 1
Query: 142 VNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXX--XXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDL-IEEIKDNHFVLIKERL--ESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKA 1131
V+++D QT L LA G+++ L+ G V +KD G T L + + + L+ A RD++ A H+ AA + L + I D+ G T LH A NGH V+ LL+ + N P+H A + LL A +N D T LH A+ H++ + L+ A+++ + G L +A+ N TN VE L+ + L L+ NS L + + +LI E++ +++N+ N T LH+ ++ + V LL GA+ + ENG +P A + + LI A
Sbjct: 474 VDVQDGSGQTPLMLAVLNGHTDCVYFLLSKGASVEAKDKWGRTALHRGAVTGHEACVEALLQHSASLPVRDSRGRTAMHLAAACGHIGSLNTV------PVIMDNCGYTPLHWACYNGHDTCVEALLEQEV-FHKMEGNSFSPLHCAVISDNEGAAELLIDTLGPAIVNATDSKSRTPLHAAAYTDHVECLQLLLGHNAQVNAIDALGKTPLMMAAENGQTNAVEVLVSRAKAD-LTLQDANKNSALHLACSKGHETSALLILEKVSDRNLINATNAALQTPLHVAAR-NGLTVVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILA 799 HSP 7 Score: 66.2402 bits (160), Expect = 2.233e-10 Identity = 79/317 (24.92%), Postives = 127/317 (40.06%), Query Frame = 1
Query: 2353 VDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFM-TFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPI-FYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSL 3297
V LLL A I FD + R A + AA GH ++ L++ H + K D+ TPLH AAS G + ++ L +L ++ N + T LH A + D + +++ N +N ++ + P+ F A LE L+ + AD+N + +G TP+ +AA G S +Q ++ + I+ D N +P H+AA L +N LIT GA+ + P+ S SDC L++ F D+P + +TSL
Sbjct: 2 VKLLLSRGANINAFDKKDRRAIHWAAYMGHMEVVRLLVS------HGTEVTCK--------------DKKAYTPLHAAASSGMISVVKYLLDLGVDINEPNAYGNTPLHVACYNGQDVVVNELIEAGAN--VNQVNEKGFAPLHFTAASRQGALCLELLVGNGADVNIKSKDGKTPLHMAAIHGRFS------------------RSQAVIQSGAE--------------------IDCEDKNGNSPLHIAARYGHELLINTLITNGANTAKRGIHGMFPL-HLAALSGFSDCCRKLLSSGF-DVDTPDDFG-RTSL 255
BLAST of Ankyrin repeat domain 28b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003991.1 (pep scaffold:Pmarinus_7.0:GL484476:255315:281660:1 gene:ENSPMAG00000003623.1 transcript:ENSPMAT00000003991.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 494.967 bits (1273), Expect = 7.952e-156 Identity = 350/1098 (31.88%), Postives = 543/1098 (49.45%), Query Frame = 1
Query: 76 LFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDD-------------DGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLS----FIENNIMDNTSLG---KKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSP 3309
L +I D D +R +Y K +VN D +T LH AAY+G + I ++L+ G VNSKD +TPL +ACAS S + L+ AD N RD W HV AA+ +V C + I+P + N++D GRTALHHA NGH E+V L+ +I+A DK R IHWAA G E++ +L+ + A++ +DK Y+ LH AS+ G I +V L++ G ++D + GN ALH+A N +V ELI + +N N +G T LH + + C++LL+ GA+ N+ S++GKSPLH A + ++ LI+ +++ +D NTPLHIA R+G+E + L+ A+ G GM P+H+A C KLL + +++ + D GR +H A +GG+++CL ++ G D++ +D ++T LH A N L+ GA ++ +DE C +HYAA + +G + N ++ S I+++ S +E+ + + G K+ PVH+A G+ + LLLE P + D GH +S +HLAAYHGH L L++ + ++ +G T L LAA +GH V+ L+ GA + ALH AA+ G V+ L L V+ + VD+ D ++++P+M+AV NGHT A L+ GA ++ KD G T+LHR A GH ECVDLLL + + L + RGR +MAA+ GH +L L+ G I + D++ TPLH+A GH C+E+L EL K + LHCA+ + + E ++ +IN PD P+ A D+V L+ L+ HNA +N D+ G +P+M+A + G + + +L+ L D + LH A + ++C ++IL+KL LIN+ + QTP HLAA + + + L+ GA + + P +SC N ++C+ + L AM SP + +SL+ SP
Sbjct: 10 LIQAIFNGDPDEVRSLIYKKEEVNAVDDEKRTPLHAAAYLGEAEIIELLVLSGARVNSKDNKWLTPLHRACASRSEAAVQTLLKHSADVNARDKNWQTPLHVAAANRAVKCAEAIIPMLSSSNVSDRAGRTALHHAAFNGHSEMVNFLVAKGANINAFDKKDRRAIHWAAYMGHTEVVKVLVAHGADVRCKDKKGYSPLHAASSSGQIGVVKLLLDLGVDIDDPNSFGNTALHVACYNGQDVVVNELIDC-----------------------------------GANVNQANERGFTPLHFAAASTHGALCLELLVNNGADVNVQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCEDRDGNTPLHIAARYGHELLINTLITNGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSAGQKYSIVSSFSNEHVLSAGFEIDTPDEFGRTCLHAAASGGNVECLNLLLSTGADMNKKDRFERTALHYAAANCNVQCVVTLVASGARLNEQDERRCTPLHYAAAADGDGSTVSFSVYNTISVQSYIDVHSTCSEAQICLEHLLRKDADPGIQDKQGYTPVHYAAAYGHRVCLELLLEQ-PGAFQSDGKSGHP-------------ISPLHLAAYHGHHGALEVLIRSLVD--LDVREGNGYTPLGLAALRGHTDCVRVLIQHGASVLLKEGPDRRTALHSAATNGHVECLR---LLVENADSNEAVDASDANEQTPVMLAVGNGHTDCASLLLSKGASINAKDNKGCTALHRGAATGHEECVDLLLQRSVDVSLRERRGRAPLHMAAACGHMGILSALVQAA---MASGAPIPLT-------------DRNGYTPLHWACYNGHDGCVELLLELDVFQKQEGNAFSPLHCAVLNDNESCAEMLIDTFGAKIINCPDAKGRMPLHAAAFTDHVECLQLLLSHNALVNVTDMAGKSPLMMACENGQATAVEVLVNSTKTDLKLQDANRNTALHLACSRSHETCALLILDKLD-DLNLINATNAALQTPLHLAARSGMATVVQVLLNKGASILAVDHNGYTPALSCAPNKSVAECLSLILGAMLPL--SPDAVPSASSLHSSP 1034
BLAST of Ankyrin repeat domain 28b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007954.1 (pep scaffold:Pmarinus_7.0:GL479092:583:36301:1 gene:ENSPMAG00000007165.1 transcript:ENSPMAT00000007954.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 276.944 bits (707), Expect = 1.870e-78 Identity = 263/990 (26.57%), Postives = 426/990 (43.03%), Query Frame = 1
Query: 334 ADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIK---ALNSSHLFLE---HLKSNSHQDLIEEIKDNHFVLIKERLESILNS--RNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVED----EYTC--MAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMM-PNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWN-ALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWF-DQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
AD N RD W HV +A+ ++ C ++P + +N++D GRTALHHA NG++E+V +L+ +++A DK R A+H A MGH ++V L+ GA+++ +G LH A+A+ H +V L+ +N + F H+ ++ QD + + E L++ ++ RN +G T+LH + + C++LL+ + A+ N S +GKSPLH A + ++ LI+ +++ D NTPLHIA R+G+E + L+ A+A G GM P+H+A C KLL T ++ +D+ GR +H A AGG+ +C+ ++ G D+ +D + G+ V+D Y+C I YN+ R+ N S ++ L + N + K+ H+A G+ L LE++ P A + D S+ ++S +HLAAYHGH + L L++ + +D GR L LAA +GH V+ LL+ GA A LH A + L +K+ +L D R+PLM+AV NGHT L+ GA+ D D T+LHR G + V L+ + L S G LL S + +++ Q L +++ H C+E+L E + N F T LHCA+ + + E ++ ++ D TP+ A DNV + L+ H A ++ D G TP+M A +G + L+ +L D LH A ++C +++LEK+ + LI+ + NQ TP HLAA N L + L++ GA + + P ++C N +DC+ + LA M
Sbjct: 5 ADVNARDKNWQTPLHVASANRAIKCADALIPLLSNVNVSDRAGRTALHHAAFNGNLEMVNLLISKGANVNAMDKRERR---------------------------------AVHWAGYMGHTEVVKMLLSNGADVNWKDKKGYTPLHAAAASGHVTVVRLLLSLKAEMNEFNGFGNTALHVACHNGQDAV----------VSELLDAGADAGHRNERGFTALHFAAASTHGAICLELLVNHHADVNAQSYDGKSPLHMTAIHGRFTRSQTLIQNGGEIDCGDKEGNTPLHIAARYGHELLINTLISNGADAARRGSHGMFPLHLAALSGFSDCCRKLL---TPGFDVDAVDE--FGRTCLHAAAAGGNAECINLLLSSGADLGKKD-----------------------RYGSIAFVQDSGNSRYSCNVRTIAMRQSYNQHSHDTRICEPLICNA-SAAALHRCLEHLLQNGAEPALRDKQGYTAAHYAAAFGHR----LCLELVSPAPALQQLLDMAGAELLRDPDSR-SLVSPLHLAAYHGHHQALEVLLRFVGE--ADLRDGHGRAPLELAAARGHTECVETLLANGACAGASSGTAAKRCPLHSAGGSAVAELLTIGKSRIKILGSINLFVRTD---RTPLMLAVTNGHTDCVLLLMDKGANPDAVDLQKHTALHRGVRLGPQDPVMNLVQISVVRRLRPHH--------PSGGGGCLLF------------------SRPVLPQAPTNLYLHSQRALCKIYY---NSHEACVELLLEQLCQKFEGNPF-TPLHCAVMNDNESCAEMLIDAMGAKIVMCQDGKGRTPLHAAAFADNVECAQLLLSHGARVDATDRRGRTPLMTGALQGQSGIVEYLVNNTKGDLSLTDDKKNTALHLACGKGHETCALLLLEKVEVV-ALIDCPNRNQHTPLHLAARNGLSTVVQDLLSKGASVLALDENGHTPALACAPNKDVADCLALILATMM 881 HSP 2 Score: 133.65 bits (335), Expect = 7.570e-32 Identity = 172/687 (25.04%), Postives = 269/687 (39.16%), Query Frame = 1
Query: 1123 IKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFI----------------------NELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSW-TPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNI-LHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNS 3111
++ ADVN +D + TPLH+A K L+ +N V+ G +H A AF M LL ++ ++N +D R VH A G + ++ ++ G D++ +D TPLH A + + R+L+ L A ++ + + A+H A +N + ++ L D GA D ++ +HFA S + G I LE++ N H D + Y K S +H+ A HG L+Q + + D+ G T LH+AA GH + + L+S GA AA +GS H PL +A +G + KL+ G DVD D +GRT LH A A G+ EC++LLL A + D G AF + + ++ I + Y+Q SHD I N + D+ T H+AA+ GH C+E++ L+ +L +A +L+ PD S +P+ A + + ALE L+ + + +D +G P+ +AA G C+ LL A + + LH AG SA I ++ L IN +TP LA N
Sbjct: 1 LRHAADVNARDKNWQTPLHVASANRAIKCADALIPLLSNVNVSDRAGRTALHHA-AFNGNLEMVNLL--ISKGANVNAMDKRE--RRAVHWAGYMGHTEVVKMLLSNGADVNWKDKKGYTPLHAAAASGHVTVVRLLLSLKAEMNEFNGFGNTALHVAC-HNGQDAVVSELLDAGA--------------------DAGHRNERGFTALHFAAASTH--GAI-CLELLVNH--------HADVNAQSYDGK----SPLHMTAIHGRFTRSQTLIQ--NGGEIDCGDKEGNTPLHIAARYGHELLINTLISNGAD---------------AARRGS-------------------------HGMFPLHLAALSGFSDCCRKLLTPGFDVDAVDEFGRTCLHAAAAGGNAECINLLLSSGADLGKKDRYGSIAFVQDSGNSRYSCNVRTI-AMRQSYNQ-----HSHDTRICEPLICNASAAALHRCLEHLLQNGAEPALRDKQGYTAAHYAAAFGHRLCLELVSPA-----------------------PALQQLLDMAGAELLRDPDSRSLVSPLHLAAYHGHHQALEVLLRFVGEADLRDGHGRAPLELAAARGHTECVETLLANGACAGASSGTAAKRCPLHSAGGSAVAELLTIGKSRIKILGS-INLFVRTDRTPLMLAVTNG 574 HSP 3 Score: 129.798 bits (325), Expect = 1.142e-30 Identity = 215/907 (23.70%), Postives = 352/907 (38.81%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIR----------------------------------LIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIK-----ALNSSH-LFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPN---------LLSENGKS--------------------------PLHFAASRNQLKQAVL-LIKAKADVNIQDDHENTPLHIACRFGYE---------KFVQMLLEYKANAFVAGEDG---MLPIHVATAFKNCGCMHKLLDNVTLKTHINNLD-DDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNL--KQTPLHLA-----VKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSF-------IENNIMDNTSLG-KKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQS-------------KDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNG-ADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRN---AFYMAASAGHKNLLMKLINYVAN 2481
L + DVN +D QT LH+A+ AD LI +VN D G T L A + + ++ +LIS GA+ N D + RA H + +K++L + +N D G T LH A A+GH+ VV++LL ++ + G +H A G +++ LLD A+ R++ +TALH A+A H I + LI+ G E+DC +GN LH+A+ H ++ LI A SH +F HL + + D L+ + +++ + G T LH + NA +C++LLL+ GA+ + ++G S PL AS L + + L++ A+ ++D T H A FG+ +Q LL+ + D + P+H+A + H+ L+ L + D DG GR + A A G +C+ET++ G K+ PLH A +L +RI I ++ V + T + + A+ N D + LL D GAN +++ H + ++ +M+ + + + P H + G +L P + + N +++ + + + +H A + + L+ IV QD GRT LH AA+ + + LLS GA+ VD+ D R+PLM G + E L+ N D+ L D T+LH A GH C LLL+ + L D RN ++AA G ++ L++ A+
Sbjct: 1 LRHAADVNARDKNWQTPLHVASANRAIKCADALIPLLSNVNVSDRAGRTALHHAAFNGNLEMVNLLISKGANVNAMDKRERRAVHWAGYMGHTEVVKMLLSNGADVNWKDKKGYTPLHAAAASGHVTVVRLLLSLKAEMNEFNGFGNTALHVACHNGQDAVVSELLDAGADAGHRNERGFTALHFAAASTHGAICLELLVNHHADVNAQSYDGKSPLHMTAIHGRFTRSQTLIQNGGEIDCGDKEGNTPLHIAARYGHELLINTLISNGADAARRGSHGMFPLHLAA------LSGFSDCCRKLLTPGFD--VDAVDEFGRTCLHAAAAGGNA-ECINLLLSSGADLGKKDRYGSIAFVQDSGNSRYSCNVRTIAMRQSYNQHSHDTRICEPLICNASAAALHRCLEHLLQNGAEPALRDKQGYTAAHYAAAFGHRLCLELVSPAPALQQLLDMAGAELLRDPDSRSLVSPLHLAAYHGH----HQALE--VLLRFVGEADLRDGHGRAPLELAAARGHTECVETLLANGACAGASSGTAAKRCPLHSAGGSAVAELLTIGKSRIKILGSINLFVRTDRTPLML---AVTNGHTDCVLLLMDKGANP-DAVDLQKHTALHRGVRLGPQDPVMNLVQISVVRRLRPHHPSGGGGCLLFSRPVLPQAPTNLYLHSQRALCKIYYNSHEACVELLLEQLCQKFEGNPFTPLHCAVMNDNESCAEMLIDAMGAKIVMCQDGKGRTPLHAAAFADNVECAQLLLSHGAR----------------------------------------VDATDRRGRTPLMTGALQGQSGIVEYLVNNTKGDLSLTDDKKNTALHLACGKGHETCALLLLEKVEVVALIDCPNRNQHTPLHLAARNGLSTVVQDLLSKGAS 848 HSP 4 Score: 92.0485 bits (227), Expect = 4.672e-19 Identity = 128/524 (24.43%), Postives = 191/524 (36.45%), Query Frame = 1
Query: 85 SILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNG-----------------------------------VTPLF-KACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILP---------------------------------------------HVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVR--PIHWAAARGXXXXXXXXXXXXX---XMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEEL-----IKALNSSH---------------------LFLEHLKS------NSHQDLIE--------EIKDNHF----------------VLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLI-KAKADVNIQDDHENTPLHIACRFGYEKFVQMLLE 1227
+ L SD R L DV+ D + +T LH AA GN+ ++L+ G D+ KD G PL A A+ H L L+ +GA+ RD + A H AA CL+L+ P V ++ D GR L A A GH E V+ LL N AS + P+H A E+L + ++N+ + D T L +A GH D V+ L++KGA D V Q + ALH + V L ++ L H L+L ++ NSH+ +E + + N F +LI I+ ++ +G T LH + DN +C LLL++GA + G++PL A + Q L+ K D+++ DD +NT LH+AC G+E +LLE
Sbjct: 286 AALSGFSDCCRKLLTPGFDVDAVDEFGRTCLHAAAAGGNAECINLLLSSGADLGKKDRYGSIAFVQDSGNSRYSCNVRTIAMRQSYNQHSHDTRICEPLICNASAAALHRCLEHLLQNGAEPALRDKQGYTAAHYAAAFGHRLCLELVSPAPALQQLLDMAGAELLRDPDSRSLVSPLHLAAYHGHHQALEVLLRFVGEADLRDGHGRAPLELAAARGHTECVETLLANGACAGASSGTAAKRCPLHSAGGSAVAELLTIGKSRIKILGSINLFVRTDRTPLMLAVTNGHTDCVLLLMDKGANPDAVDLQKHTALHRGVRLGPQDPVMNLVQISVVRRLRPHHPSGGGGCLLFSRPVLPQAPTNLYLHSQRALCKIYYNSHEACVELLLEQLCQKFEGNPFTPLHCAVMNDNESCAEMLIDAMGAKIVMCQDGKGRTPLHAAAFADNV-ECAQLLLSHGARVDATDRRGRTPLMTGALQGQSGIVEYLVNNTKGDLSLTDDKKNTALHLACGKGHETCALLLLE 808 HSP 5 Score: 88.9669 bits (219), Expect = 4.631e-18 Identity = 89/343 (25.95%), Postives = 137/343 (39.94%), Query Frame = 1
Query: 2266 IMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVAN----------KYHQGDFI---EKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFM-TFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
+ + ADV+ +D +T LH A+AN ++C D L+ + + + D GR A + AA G+ ++ LI+ AN H ++ E + N W D+ TPLH AA+ GH + +L L EM NGF T LH A + D + +L A D + ++ F A LE L+ H+AD+N Q +G +P+ + A G + +Q ++ G+ I+ D TP H+AA L +N LI+ GAD + P+ S SDC L F
Sbjct: 1 LRHAADVNARDKNWQTPLHVASANRAIKCADALIPLLSNVNVSDRAGRTALHHAAFNGNLEMVNLLISKGANVNAMDKRERRAVHWAGYMGHTEVVKMLLSNGADVNWKDKKGYTPLHAAAASGHVTVVRLLLSLKAEMNEFNGFGNTALHVACHNGQDAVVSELLD-AGADAGHRNERGFTALHFAAASTHGAICLELLVNHHADVNAQSYDGKSPLHMTAIHGRFT------------------RSQTLIQNGGE--------------------IDCGDKEGNTPLHIAARYGHELLINTLISNGADAARRGSHGMFPL-HLAALSGFSDCCRKLLTPGF 303 HSP 6 Score: 55.4546 bits (132), Expect = 8.954e-8 Identity = 48/166 (28.92%), Postives = 81/166 (48.80%), Query Frame = 1
Query: 259 NGVTPLFKACASNSHNVLTVLISS-GAD-TNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTS-ISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRD---KDDYTALHIASAMGHIDIVIRLIEKGAEL 738
N TPL A +++ + +LI + GA C+D K H A ++V+C +L+L H ++ TD GRT L G +V+ L++N +S +D +H A +G LLL+ + + D ++ +T LH+A+ G +V L+ KGA +
Sbjct: 684 NPFTPLHCAVMNDNESCAEMLIDAMGAKIVMCQDGKGRTPLHAAAFADNVECAQLLLSHGARVDATDRRGRTPLMTGALQGQSGIVEYLVNNTKGDLSLTDDKKNTALHLACGKGHETCALLLLEKVEVVALIDCPNRNQHTPLHLAARNGLSTVVQDLLSKGASV 849
BLAST of Ankyrin repeat domain 28b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000093.1 (pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000093.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 208.764 bits (530), Expect = 9.229e-56 Identity = 220/846 (26.00%), Postives = 373/846 (44.09%), Query Frame = 1
Query: 409 LKLILPHVLG---INITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEE----IKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGF-MTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLL 2922
L+ ++ H+ G IN + +G ALH A GH++VV LL I + K G +H AA G +I+ +L++ AN+N + ++ +T L++A+ H++IV L++ GA T G L +A H +V L+++ + L L + +D ++ H + ++ +LN G T LHI + N + LLL GA + + NG +PLH AA R LL+ A ++ + TPLH A R G+EK ++MLLE A ++G+ P+H+AT ++ C+ LL + ++++ D L +H A G + + ++ GG+ + TPLH+A K N + +L+K GASI E IH A+ ++++LL NGA S N+ T P+H A +G + + LL+ ++ ++++D L H+A+ G +EI+ L+Q S T SG T L+ A+ +GH LL GA + V K + LH A+ G ++ + ++ LE S D ++ +PL +A H + A L+ GA G T LH A +E +LL+ A+ + +G ++AA GH +++ L+ A+ + LT +H AA N E+L + ++ +T T LH A + + +L+ N L+N + +TP+ A + + + L+ H A N NG T + IA + G +S ++ L
Sbjct: 23 LERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKM--MLNQTTESGFTPLHIAAHYGNMN-VATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGR---QAPVDDVTLDYL--TPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHL-NVVQLLLQNGA------------SSNATNVRGET--------PLHMASRAGQLEVVKTLLQ---------------SGARVGVKAREDQTPL-HIASRLGKAEIVQLLLQRGSDPNAPTA--SGSTPLYFASREGHGDVASLLLENGADISPVTKKGF-TPLHIASKYGRLE-----VATLLLEKYAS-ADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASIS--------------------LATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLR--NRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIARRLGYISVVDTL 792 HSP 2 Score: 191.045 bits (484), Expect = 5.797e-50 Identity = 201/827 (24.30%), Postives = 350/827 (42.32%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNC--------------------------RDNKWN---RAFHVCAAHNSVDCLKLILPH--------VLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPN---EAKMDCIKGHV--------------DSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGH 2442
L + +++ TALH+AA G ++I +L+++G ++N++ NG TPL+ A N ++ L+ +GA+ + D K A H+ A + + L+L H + +N T G T LH A G++ V +LL+ ++ + +NG+ P+H AA RG+ ++ LLLD A ++ + +D T LH A+ GH ++ L+E+ A + T G + LH+A+ H V+ L+ Q ++++ ++ LT LH+ + + ++ LLL G PN + NG +PLH A +N++K LL+K A ++ + TP+H+A G+ VQ+LL+ A++ G P+H+A+ G L+ ++T+++ G + + QTPLH+A +L I ++L++ G+ + +++A+ GD+ LL +NGA+I SP+ KK P+H A G + LLLE + + K HV D + + + + + +H+AA E+ L+++ ++ + TQ G LHLAA +GHA V LL A + K A+H AA + V+ ++ L K+ V++ + +PL +A G+ + L+ N A V+ K G T LH+A GH V+ LL A G A +A G+
Sbjct: 63 LKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLL----------------GRQAPVDDVTLDY-------------------LTPLHVAAHCGH-YRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMAS--------------------------------------RAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFAS-REGHGDVASLLLENGADI-SPVT-------------------KKGFTPLHIASKYGRLEVATLLLEKYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQ--GVAPLHLAAQEGHADMVALLLGRHASISLATKG-GLTAMHLAAQEDKVN------VAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIARRLGY 785 HSP 3 Score: 177.563 bits (449), Expect = 1.071e-45 Identity = 185/732 (25.27%), Postives = 324/732 (44.26%), Query Frame = 1
Query: 895 KDNHFVLIKERL--ESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLP-IHVATAFKNCGCMHKLLD-----NVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANIL-------SPINI---NDHLSFIE-----NNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEM--MPNEAKMDCIKG-HVDSSQND--------------YQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVA-------NKYHQGDFIEKSHDIFINEL------KSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMK-STNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLE 2928
K+ H ++ E L E+ +++ G T+LHI + + V +L+ +GAN N S+NG +PL+ AA N L+ L+ A+ ++ + TPL +A + G+E+ V +LLE V LP +H+A + LL +VT K +N + G +H A G++ ++ LG + TPLH+A K N + ++L+ GA ID + +H AA E ++ +L + A IL SP+++ +HL+ ++ +D+ +L + P+H A G++ LLL+ PN ++ H+ +N + + + L+ IH+A++ GH ++ L+Q + + + + G T LH+A+ G VK LL GA+ V LH A+ G + + ++ R S ++ +PL A + GH A L+ NGAD+ G T LH A+ G +E LLL+ A + G ++A H+ + + L++ A N Y K + + + ++ ++ Q + PLH AA GH + + +L + +T G +T +H A E + K + +NT K +TP+ A H N+ + L+ + A +N + NG TP+ AA++G +N LL+
Sbjct: 52 KEGHVDVVTELLKREAEIDTATKVGNTALHI-AALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKV-----RLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGF--TPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHE-KVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTL--DYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASS--NATNVRGETPLHMASRAGQLEVVKTLLQSGAR-VGVKAREDQTPLHIASRLGKAEIVQLLL------QRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKAD--VNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQ 761 HSP 4 Score: 124.79 bits (312), Expect = 3.656e-29 Identity = 167/726 (23.00%), Postives = 294/726 (40.50%), Query Frame = 1
Query: 1084 AASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDN---GANILSPINI---------------NDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMK-STNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQN---ILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI 3189
AA L++ + +K D+N + + LH+A + G+ V LL+ +A + TA K +G +H A G + ++ G +I+ + TPL++A + N+ I + L+ GA S+ ED +T +A+ A+ ++ LL ++ G L ++I ++H + + + +M N + P+H A GN + LLL + + D+ +++ + L H+AA G++ ++ L+ +K + T+ R G T LH AA GH ++ LL A P + LH A+QG A +++L R++ VD + +PL +A GH R A+ L+ G + + + G T LH A ++ ++LLL A I G ++A+ GH N++ L+ N S + TPLH A+ G ++ L + + T LH A E ++ +L+ ++ N P TP+++A + + + L+ + ADI+ G TP+ IA+K G L LLLE K+A D +N LH A +++L+K +S N TP H+AA + L+ GA+ + + P+
Sbjct: 17 AARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAE-------------IDTATK-------------------------VGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAV---ALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFT-PLHIAAHYGNMNVATLLLNL---------------GAAVDFTARNGITPL-HVAAKRGNNNMVKLLLDRGAK--IDTKTRDGLTPLHCAARSGHEKVIEMLLERDA-PILAKTKNGLSPLHM-ATQGEHLACVQLLLG-----RQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQ--------------------NGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDP--NAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLE----KYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGAS----PHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPL 645 HSP 5 Score: 103.219 bits (256), Expect = 1.908e-22 Identity = 97/376 (25.80%), Postives = 166/376 (44.15%), Query Frame = 1
Query: 112 LRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKAN 1239
++ L + V +K DQT LH+A+ +G + I +L++ G D N+ +G TPL+ A +V ++L+ +GAD I+ G T LH A G +EV +LL+ S KNG+ P+H A ++ LLLD A+ + K+ YT LHIA+ +++ L+E GAE + +T QG L HL + H D++ + H + ++ GLT++H+ +Q D + ++L + A+ N ++ +PLH A+ +K L++ +A VN + + TPLH A + G+ V LL+++A+
Sbjct: 459 VKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGAD---------------------------------ISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPL----------------------HLAAQ----EGHADMVALLLGRH---------ASISLATKGGLTAMHLAAQEDKVN-VAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEAS 765 HSP 6 Score: 99.3673 bits (246), Expect = 2.790e-21 Identity = 141/580 (24.31%), Postives = 231/580 (39.83%), Query Frame = 1
Query: 1747 VHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYY----------------------------WNALHYAASQGSVDALNEMILSVKLE-----NRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKS-TNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLA------AMFSSTDSP------------ANLALKTSLNLSP--KKGYV 3324
+H A G+ D ++ E++ EA++D +++ +H+AA G ++I+ LV+ F NI + Q ++G T L++AA + H VKFLL GA + +D + ALH AA + D N L ++ E K +++ E +PL IA G+ A L+ GA VD G T LH A G+ V LLLD AKI+ G + AA +GH+ ++ L+ E+ I ++ L+PLH A H C+++L + T ++T LH A + C L + N +TP+ A + + +E L+ H A I+ +G TPI +A+ G L+ + LLL QN G S+ N+ + +TP H+A+ + L+ GA + +K + Q P+ R KA + +++ L A +S +P A+L L+ ++SP KKG+
Sbjct: 47 LHLASKEGHVD---VVTELLKREAEIDTATKVGNTA-------------LHIAALAGQTDIVRVLVE-FGANI-NAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARK---DDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLL-------------ERDAPILAK-------TKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVA--AHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLL--------------QN-----GASS-------------------NATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKA-EIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFT 544 HSP 7 Score: 84.7297 bits (208), Expect = 7.709e-17 Identity = 87/333 (26.13%), Postives = 148/333 (44.44%), Query Frame = 1
Query: 2176 KSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVA--NKYHQGDFIEKSHDIFINELKSMWF-----------DQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVL--------KIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQN---ILHYAGQSADDSCGIIILEK-LPCLKKLINSLDNNQQTPAHLA 3099
++L+D D + + A +NG+ + G D++ + G +LH A+ GHV+ V LL A+I+ G A ++AA AG +++ L+ + A N Q F N L+ + F +D TPL A +GH + +L E SD T G + I ++ D+T L + + ++N + +TP+ A H N+N L+ A +++ NG TP+ +AAK G + + LLL+ + A +D ++ LH A +S + ++LE+ P L K N L +P H+A
Sbjct: 2 ETLLDKSD--AATSFLRAARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLE-SD----TKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLD----RGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGL-----SPLHMA 318 HSP 8 Score: 80.1073 bits (196), Expect = 2.305e-15 Identity = 64/228 (28.07%), Postives = 105/228 (46.05%), Query Frame = 1
Query: 76 LFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQG 759
L+ + E D L N D++ T LH+A+ G +A +L++ + K NG+TPL A + V +L+ GA + H+ A N ++ K++L N+ G LH A GH ++V +LL + SIS + K G+ +H AA + + +L + A++N K YT LH+AS G+I +V L+ A ++ T G
Sbjct: 513 LYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNG 740
BLAST of Ankyrin repeat domain 28b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 196.823 bits (499), Expect = 5.080e-52 Identity = 214/801 (26.72%), Postives = 367/801 (45.82%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVR--PIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEEL------IKALNSSHLFLEHLKSNS-HQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMM----PNEAKMDCIKG-HV--------------DSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGH 2442
L +D+N + ALHLA+ G+ ++ L+K ++++ G T L A + +++ VL+ GA+ N + ++ A N ++ +K +L + ++ DG T L A+ GH +VV +LL+++T K VR +H AA + D LLL ++ N ++ K +T LHIA+ G++++ L+ GA +D G LH+A+ + N+V+ L I L H + S H+ +IE ++ ER IL ++ GL+ LH+ +Q ++ CV LLL A + ++ + +PLH AA + A LL+ + N + + TPLHIAC+ K +++LL++ A+ E G+ PIHVA+ + + LL N ++ N+ G +H A G L+ ++T+++ G + + QTPLH+A +L I ++L++ G+ + +++A+ GD+ LL +NGA+I SP+ KK P+H A G + LLLE P A + + HV D + + + + + +H+AA E+ L+++ ++ + TQ G LHLAA +GHA V LL A + K A+H AA + V+ ++ L K+ V++ + +PL +A G+ + L+ N A V+ K G T LH+A GH V+ LL A G A +A G+
Sbjct: 31 LKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDT------KGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIE--------MLLERDAPIL-AKTKNGLSPLHMATQGEHL-ACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGA-SSNATNVR----GETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFAS-REGHGDVASLLLENGADI-SPVT-------------------KKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQ--GVAPLHLAAQEGHADMVALLLGRHASISLATKG-GLTAMHLAAQEDKVN------VAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIARRLGY 780 HSP 2 Score: 196.052 bits (497), Expect = 8.480e-52 Identity = 223/870 (25.63%), Postives = 369/870 (42.41%), Query Frame = 1
Query: 322 ISSGADTN-CRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSL-DEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGF-MTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLL 2922
+ G D N C N N A H+ + VD + +L I+ G TALH A G ++V++L++ +I+A +NG P++ AA LEI+ LLDN AN ++ +D +T L +A GH +V L+E T+G L + N++ L L+H E + + G T LHI + N + LLL GA + + NG +PLH AA R LL+ A ++ + TPLH A R G+EK ++MLLE A ++G+ P+H+AT ++ C+ LL + ++++ D L +H A G + + ++ GG+ + TPLH+A K N + +L+K GASI E IH A+ + ++++LL NGA S N+ T P+H A +G + + LL+ ++ ++++D L H+A+ G +EI+ L+Q S T SG T L+ A+ +GH LL GA + V K + LH A+ G ++ + ++ LE S + ++ +PL +A H + A L+ GA G T LH A +E +LL+ A+ + +G ++AA GH +++ L+ A+ + LT +H AA N E+L + ++ +T T LH A + + +L+ N L+N + +TP+ A + + + L+ H A N NG T + IA + G +S ++ L
Sbjct: 31 LKGGMDINTCNQNGLN-ALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLES-------DTKGKVRLPALH-------IAARKDDTNAAALLLQH-------------------------EHNADVTSKSGFTPLHIAAHYGNMN-VATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGR---QAPVDDVTLDYL--TPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVAS-FMGHLNVVQLLLQNGA------------SSNATNVRGET--------PLHMASRAGQLEVVKTLLQ---------------SGARVGVKAREDQTPL-HIASRLGKAEIVQLLLQRGSDPNAPTA--SGSTPLYFASREGHGDVASLLLENGADISPVTKKGF-TPLHIASKYGRLE-----VATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASIS--------------------LATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLR--NRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIARRLGYISVVDTL 787 HSP 3 Score: 171.785 bits (434), Expect = 4.987e-44 Identity = 184/730 (25.21%), Postives = 323/730 (44.25%), Query Frame = 1
Query: 895 KDNHFVLIKERL--ESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLP-IHVATAFKNCGCMHKLLDNVTLKTHINNLD-DDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANIL-------SPINI---NDHLSFIE-----NNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEM--MPNEAKMDCIKG-HVDSSQND--------------YQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLD--CNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVA-------NKYHQGDFIEKSHDIFINEL------KSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMK-STNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLE 2928
K+ H ++ E L E+ +++ G T+LHI + + V +L+ +GAN N S+NG +PL+ AA N L+ L+ A+ ++ + TPL +A + G+E+ V +LLE V LP +H+A + LL H +N D G +H A G++ ++ LG + TPLH+A K N + ++L+ GA ID + +H AA E ++ +L + A IL SP+++ +HL+ ++ +D+ +L + P+H A G++ LLL+ PN ++ H+ +N + + + L+ IH+A++ GH ++ L+Q + + + + G T LH+A+ G VK LL GA+ V LH A+ G + + ++ R S ++ +PL A + GH A L+ NGAD+ G T LH A+ G +E LLL+ +A ++ G ++A H+ + + L++ A N Y K + + + ++ ++ Q + PLH AA GH + + +L + +T G +T +H A E + K + +NT K +TP+ A H N+ + L+ + A +N + NG TP+ AA++G +N LL+
Sbjct: 53 KEGHVDVVTELLKREAEIDTATKVGNTALHI-AALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKV-----RLPALHIAARKDDTNAAALLLQ------HEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHE-KVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTL--DYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASS--NATNVRGETPLHMASRAGQLEVVKTLLQSGAR-VGVKAREDQTPLHIASRLGKAEIVQLLL------QRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKAD--VNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQ 756 HSP 4 Score: 159.458 bits (402), Expect = 3.894e-40 Identity = 181/666 (27.18%), Postives = 312/666 (46.85%), Query Frame = 1
Query: 67 IPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGA--DTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIK---ALNSSHLFLE---HLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANA--FVAGEDGMLPIHVATAFKNCGCMHKLLD-NVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVY-PVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQ-IFSKNIVSTQDRSGRTALHLAAYQGH 2025
+P L + + D++ L ++ + ++ T LH+AA+ GN N+A +L+ G V+ NG+TPL A ++N++ +L+ GA DT RD H A ++++L I +G + LH A H+ V++LL + + + P+H AA G + LLLD N R + +T LHIA I ++ L++ GA + T G +H+AS H N+V+ L++ + N++++ E H+ S + Q +E +K L++ + +R Q T LHI S++ A + V LLL G++PN + +G +PL+FA+ A LL++ AD++ TPLHIA ++G + +LLE A+A VAG++G+ P+HVAT + + LLD + + N G +H A L+ + ++ LG + + PLHLA + + + +L+ ASI + + A+H AA +K +N+ + L+ + ++ T K+ Y P+H A GN + LL N A ++ ++N Y + +H AA GH+ ++N L+Q S N ++ +G TAL +A G+
Sbjct: 173 LPALHIAARKDDTNAAALLLQHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLT--PLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQ--LEVVK----TLLQSGARVGVKAREDQ--TPLHIASRLGKA-EIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKN------GYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDK------------------VNVAEILTKHKADVNTTT----KLCYTPLHVASHYGNIKMVNFLLR---NRALVNA------KTRNGY-------TPLHQAAQQGHTHVVNALLQHEASPNELTA---NGNTALAIARRLGY 780 HSP 5 Score: 121.709 bits (304), Expect = 2.906e-28 Identity = 170/721 (23.58%), Postives = 291/721 (40.36%), Query Frame = 1
Query: 1084 AASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA--SIDVEDEYTCMAIHYAAMYNKEGDILRLLFDN---GANILSPININDH--------LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMK-STNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDK--SNQN---ILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI 3189
AA L++ + +K D+N + + LH+A + G+ V LL+ +A + TA K +G +H A G + ++ G +I+ + TPL++A + N+ I + L+ GA S+ ED +T +A+ A+ ++ LL ++ G L ++I L + D TS K P+H A GN + LLL + + D+ +++ + L H+AA G++ ++ L+ +K + T+ R G T LH AA GH ++ LL A P + LH A+QG A +++L R++ VD + +PL +A GH R A+ L+ G + + + G T LH A ++ ++LLL A I G ++A+ GH N++ L+ N S + TPLH A+ G ++ L + + T LH A E ++ +L+ ++ N P TP+++A + + + L+ + ADI+ G TP+ IA+K G L LLLE K+A D + QN LH A +++L+K +S N TP H+AA + L+ GA+ + + P+
Sbjct: 18 AARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAE-------------IDTATK-------------------------VGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAV---ALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTS--KSGFTPLHIAAHYGNMNVATLLLNL---------------GAAVDFTARNGITPL-HVAAKRGNNNMVKLLLDRGAK--IDTKTRDGLTPLHCAARSGHEKVIEMLLERDA-PILAKTKNGLSPLHM-ATQGEHLACVQLLLG-----RQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQ--------------------NGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDP--NAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLE----KYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGAS----PHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPL 640 HSP 6 Score: 106.301 bits (264), Expect = 1.711e-23 Identity = 138/549 (25.14%), Postives = 239/549 (43.53%), Query Frame = 1
Query: 1747 VHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEM--KSTNGFMTFLHCAIDSKCDETLECV-LKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLA------AMFSSTDSP------------ANLALKTSLNLSP--KKGYV 3324
+H A G+ D ++ E++ EA++D +++ +H+AA G ++I+ LV+ F NI + Q ++G T L++AA + H VKFLL GA + +D + L A QG +E ++ + LE+ D+ + + L IA + T A L+ + + D+ G T LH A G++ LLL+ A ++ G ++AA G+ N++ L++ +G I+ +D LTPLH AA GH IEML E + K+ NG ++ LH A E L CV L + ++ TP+ A H + + L+ + N + +NG TP+ IA K+ + + LLL+ +S +H A + ++L+ N+ + +TP H+A+ + L+ GA + +K + Q P+ R KA + +++ L A +S +P A+L L+ ++SP KKG+
Sbjct: 48 LHLASKEGHVD---VVTELLKREAEIDTATKVGNTA-------------LHIAALAGQTDIVRVLVE-FGANI-NAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGF-TPLAVALQQG-----HEQVVGLLLES-----DTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLD-------RGAKIDTK-------------TRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNG-LSPLHMATQG---EHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLK-HGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGAS----SNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKA-EIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFT 537
BLAST of Ankyrin repeat domain 28b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007446.1 (pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007446.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 160.229 bits (404), Expect = 7.015e-40 Identity = 135/460 (29.35%), Postives = 212/460 (46.09%), Query Frame = 1
Query: 169 TALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA 1548
TALH+AA+ G+ A +L+ G + N + +NG TPL AC N V+ +L+ GA HV A +++ + ++L N T+ G TALH A G EVV+ LL N + A + P+H AA G LEI+ LLL + A+ + + YT LH+A+ GH D+ L+E GA L T +G LH+AS + L++ S ++ GLT LH+ S DN + LLL GA+P+ ++NG +PLH AA ++QL+ A L++ A+ N PLH+ + G+ +LL A+ A + G+ P+H+A L+ + H+N G +V C G++K + +++ G D++ + TPLH A + + I +L+K GA
Sbjct: 74 TALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASP-----------------------------------DAAGKNGLTPLHVASHYDN-QKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKH---GAHVNATTKLGYTPLIVACHY--GNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGA 492 HSP 2 Score: 149.058 bits (375), Expect = 1.774e-36 Identity = 134/539 (24.86%), Postives = 241/539 (44.71%), Query Frame = 1
Query: 865 NSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPININDHLSFIE------NNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGH 2442
+ H+ ++E +L+++ + ++N GL+ LH+ +Q D+ +CV +L+ Y A + ++ + + LH AA + A +L+ A+ N++ + TPLHIAC+ + +++LL+Y A+ E G+ P+HV+ N + LL N G +H A G + + +++R G + + +QTPLH+A +L I ++L++ AS D +H AA E D+ +L ++GA++ +P+++ +E + GK + P+H A N +LLL D + + + + + +H+AA EI L++ ++ T R G LHL A +GHA LL+ A K + LH AA + V+ ++ + V++ + +PL++A G+ + L+ +GADV+ K G T LH+A GH V+LLL C A+ G A +A G+
Sbjct: 16 SGHEQVVE-------ILLEQGAPILAKTKN--GLSPLHMATQGDHV-ECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVR-----GETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHE-DVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLL----------------DQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAIT--RQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGL-SPLHLAAQEDKVNVAEILV------KHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGY 513 HSP 3 Score: 139.428 bits (350), Expect = 1.826e-33 Identity = 143/588 (24.32%), Postives = 241/588 (40.99%), Query Frame = 1
Query: 1168 TPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLEC 2931
TPLH A R G+E+ V++LLE A ++G+ P+H+AT + C+ L+ + ++++ D L +H A G + + ++ G + + TPLH+A K N + +L+K GASI+ E +H +A +I+ +L GA S N+ T+L H A +G + + LL + +Q D +++++ L H+AA G EI+ L+Q + +T + G T LH+AA +GH LL GA AV + LH A+ G ++ + ++ R + D+ ++ +PL +A + + A L+ GA G T LH A +E LL+ A+ +G ++ A GH ++ L+ A+ H + L+PLH AA N E+L + + +N K +TP+ A H N+ + L+ H AD+N + NG TP+ AA++G +NLLL+C
Sbjct: 8 TPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQ---YRAPVDDITLDYL--TALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNL-NIVLILLQGGA------------SPNATNVRGETAL--------HMAARAGQTEVVRSLLR---------------NGAQVDAKAREEQTPL-HIAARLGKLEIVQLLLQHMASPDAATSN--GYTPLHVAAREGHEDVTAILLEHGAS-LAVTTKKGFTPLHVASKYGKMEVASLLL------QRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHA--------------------TKSGLSPLHLAAQEDKVNVAEIL----------------------------------VKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKC 490 HSP 4 Score: 136.346 bits (342), Expect = 1.773e-32 Identity = 150/545 (27.52%), Postives = 246/545 (45.14%), Query Frame = 1
Query: 457 DGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRN---LVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEG--DILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAV 2076
DG T LH A +GH +VV+ILL+ I A KNG+ P+H A +E + +L+ A ++ D TALH+A+ GH L++KGA + G LH+A N ++E L+K S E + H + + + VLI + + N+ N +G T+LH+ ++ + V LL GA + + ++PLH AA +L+ LL++ A + + TPLH+A R G+E +LLE+ A+ V + G P+HVA+ + LL D G+N +H A + K ++ G H TPLH+A K + I L++ GA + +H A +EG D+ LL A++ +H + K + P+H A + +L++ HV+++ +K LI +A ++G+ +++N+L+Q + V+++ ++G T LH AA QGH V LL CGA+P V
Sbjct: 5 DGLTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAF--MGNLNIVLILLQGGASPNATNVRGETALHMAARAGQT-EVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFA--------SPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGA---QEGHADVASLLLARYADV-------NHAT-------------KSGLSPLHLAAQEDKVNVAEILVKH----------GAHVNAT-----TKLGYTPLI-VACHYGNIKMVNFLLQHGAD--VNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDV 497 HSP 5 Score: 133.265 bits (334), Expect = 1.621e-31 Identity = 106/382 (27.75%), Postives = 190/382 (49.74%), Query Frame = 1
Query: 145 NIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLE--SILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVA 1284
N++ T LH+A + ++L+KYG + + +G+TP+ + + N++ +L+ GA N + + A H+ A + ++ +L + ++ + +T LH A G +E+V++LL + S A+ NG P+H AA G ++ +LL++ A++ + K +T LH+AS G +++ L+++ A D G LH+AS ++ + L+ S H N + L K + + LE + N+ QG+ LH+ +Q +A LLLA A+ N +++G SPLH AA +++ A +L+K A VN TPL +AC +G K V LL++ A+ ++G P+H A
Sbjct: 99 NVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHA----TAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHA-DVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQA 475 HSP 6 Score: 115.546 bits (288), Expect = 3.943e-26 Identity = 110/390 (28.21%), Postives = 175/390 (44.87%), Query Frame = 1
Query: 169 TALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDD---------------------------------YTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKAL------NSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQML 1221
T +H++A++GN NI IL++ G N+ +V G T L A + V+ L+ +GA + + + H+ A ++ ++L+L H+ + S+G T LH A GH +V ILL++ S++ + K G P+H A+ G +E+ +LLL A+ + K+ YT LHIA+ ++I L+E GAE + +T QG LHL + H ++ L+ S L HL + + + EI H + N+ G T L + N + V+ LL +GA+ N ++NG +PLH AA + LL+K A N + NT L IA R GY V L
Sbjct: 140 TPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHV--------NATTKLGYTPLIVACHYGNI-KMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTL 520 HSP 7 Score: 115.161 bits (287), Expect = 5.002e-26 Identity = 127/535 (23.74%), Postives = 231/535 (43.18%), Query Frame = 1
Query: 1057 ENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPININDHLSFIE------NNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEML 2622
++G +PLH AA + +L++ A + + + +PLH+A + + + VQ+L++Y+A D + +HVA +CG H V L N G +H A ++ +E +++ G I TP+H++ + N I IL++ GAS + + A+H AA + +++R L NGA + +P++I L +E ++ + P+H A G+ D +LLE + A + KG + +H+A+ +G E+ + L+Q F+ ++G T LH+A++ + LL GA P A K+ Y LH AA + +++ ++ L + +++ +PL + Q GH A L+ ADV+ G + LH A V ++L+ A + G +A G+ +K++N++ H D K+ + + TPLH AA +GHT+ + +L
Sbjct: 4 QDGLTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAA---HCG--HYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQT-EVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLA-VTTKKG---------------FTPLHVASKYGKMEVASLLLQRFASP--DAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGY-TPLHIAAKK------DQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGN----IKMVNFLLQ--HGADVNSKTKNGY--------------TPLHQAAQQGHTHIVNLL 487 HSP 8 Score: 84.3445 bits (207), Expect = 1.397e-16 Identity = 80/311 (25.72%), Postives = 134/311 (43.09%), Query Frame = 1
Query: 2212 SPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQG--DFIE-----KSHDIFINELKSMW------FDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTN-GFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAA 3102
+PL A ++GH + E L+ GA + K G + LH AT HVECV +L+ A ++ A ++AA GH L++ AN + F K + I + EL + + LTP+H +A G+ N + +L + +TN T LH A + E + +L+ N ++ + TP+ A + ++ L+ H A + NG TP+ +AA+EG +LLE A+ K LH A + ++L++ ++ N TP H+A+
Sbjct: 8 TPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLR--NGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLE-HGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFAS----PDAAGKNGLTPLHVAS 311 HSP 9 Score: 56.6102 bits (135), Expect = 3.885e-8 Identity = 42/127 (33.07%), Postives = 57/127 (44.88%), Query Frame = 1
Query: 139 DVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKIL 519
DVN + LHLAA N+A+IL+K+G VN+ G TPL AC + ++ L+ GAD N + H A + L+L N +G TAL A G+I VV L
Sbjct: 394 DVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTL 520 HSP 10 Score: 52.373 bits (124), Expect = 6.938e-7 Identity = 68/258 (26.36%), Postives = 121/258 (46.90%), Query Frame = 1
Query: 2557 QDYLTPLHFAASRGHTNCIEMLYELSDEM--KSTNGFMTFLHCAIDSKCDETLECVLKI-ANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGY 3321
QD LTPLH AA GH +E+L E + K+ NG ++ LH A E ++ +++ A D I T D T + A H + + L+ A+ N + +NG TP+ IA K+ + + LLL+ A V +S +H + + + +I+L+ N+ + +T H+AA + +L+ GA + K + Q P+ R K + +++ L M S + +N T L+++ ++G+
Sbjct: 4 QDGLTPLHCAARSGHEQVVEILLEQGAPILAKTKNG-LSPLHMATQGDHVECVQVLMQYRAPVDDI-TLDYL--TALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEA-VTESGLTPMHVSAFMGNLNIVLILLQG----GASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKL-EIVQLLLQHMASPDAATSN--GYTPLHVAAREGH 249
BLAST of Ankyrin repeat domain 28b vs. Ensembl Yeast
Match: NAS6 (Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, also known as p28, which interacts with the Rb tumor suppressor and CDK4/6 [Source:SGD;Acc:S000003464]) HSP 1 Score: 69.707 bits (169), Expect = 1.560e-13 Identity = 56/179 (31.28%), Postives = 90/179 (50.28%), Query Frame = 1
Query: 247 SKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRD----NKWNRAFHVCAAHNSVDCLKLIL--PHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXX-XXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEK-GAELDCVTTQG 759
KD +G PL + + +H + + L+S + N D + W FH+ + +++ +K + P +N + G T LH AV EV + L++N S+ DK P+H AA+ G L+++ LL + +N +DK +T L A A GH D + L+EK GAE D V +G
Sbjct: 31 QKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWT-PFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKG 208 HSP 2 Score: 60.8474 bits (146), Expect = 1.634e-10 Identity = 47/150 (31.33%), Postives = 78/150 (52.00%), Query Frame = 1
Query: 1165 NTPLHIACRFGYEKFVQMLLEYKANAFVAG-EDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDD--DGLGRNLVHCAVAGGSLKCLETII--RLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAA 1599
N PLH AC VQ LL K + + +DG +P+H + +F+ H++ + K NLDD D G H A + G+L+ ++++ L D++ N T LHLAV F +++ LI+ GAS+ ++D++ + +H AA
Sbjct: 3 NYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQ----AHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAA 148 HSP 3 Score: 60.077 bits (144), Expect = 2.488e-10 Identity = 55/204 (26.96%), Postives = 96/204 (47.06%), Query Frame = 1
Query: 1975 QDRSGRTALHLA-AYQGHAINVKFLLSCGAKPTAVDKDYY-----WNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCN-AKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIE----KSHDIFINELKSMWF 2553
+D+ GR LH + ++Q H I FLLS K V+ D Y W H A S G++ E++ S+ K ++ + + L +AV ++ LI NGA V +KD + + LHRA + G ++ ++LL + + D +G + A + GH + + L+ +Y D ++ K+ D+ +NE +F
Sbjct: 32 KDQDGRIPLHWSVSFQAHEI-TSFLLS---KMENVNLDDYPDDSGWTPFHIACSVGNL----EVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEY---DLVDNKGAKAEDVALNEQVKKFF 224 HSP 4 Score: 52.7582 bits (125), Expect = 7.005e-8 Identity = 43/139 (30.94%), Postives = 65/139 (46.76%), Query Frame = 1
Query: 2554 DQDYLTPLHFAASRGHTNCIEMLYELS---DEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLI-LHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVD 2958
D TP H A S G+ ++ LY+ D K TN +T LH A+ K E + + I N + DK++ P+ A ++ +E L L + +N+QD G TP+ A EG LL+E ++ LVD
Sbjct: 69 DDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFL--IENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVD 205 HSP 5 Score: 48.1358 bits (113), Expect = 2.384e-6 Identity = 52/190 (27.37%), Postives = 86/190 (45.26%), Query Frame = 1
Query: 1036 ANPNLL---SENGKSPLHFAASRNQLKQAVLLIKAKADVNI---QDDHENTPLHIACRFGYEKFVQMLLE--YKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDN---VTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGD-IHHEDNLKQTPLHLAVKLNNFMITRILI-KLGASIDVED 1566
+ P+LL ++G+ PLH++ S + L+ +VN+ DD TP HIAC G + V+ L + K + G+ +H+A K L++N V +K N + +H A + GSLK +E + LG ++ +D TPL A+ + +L+ K GA D+ D
Sbjct: 24 SKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIP--------LHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVD 205
BLAST of Ankyrin repeat domain 28b vs. Ensembl Yeast
Match: AKR1 (Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats; AKR1 has a paralog, AKR2, that arose from the whole genome duplication; any of several human homologs encoding DHHC-type zinc fingers (ZDHHC) can complement temperature sensitivity of yeast akr1 null mutant [Source:SGD;Acc:S000002672]) HSP 1 Score: 59.3066 bits (142), Expect = 3.353e-9 Identity = 49/160 (30.63%), Postives = 75/160 (46.88%), Query Frame = 1
Query: 1075 LHFAASRNQLKQAVLLIKAKADVNIQDDH-ENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGR-NLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGA 1548
LH+A+ N+L L+ ADVN + TPLH A R+GY V LL++ A+ + + G +H++ N + +L NV K ++ D GR +L+ A G SL E +++ G I D TPLH + + LI+ GA
Sbjct: 113 LHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAE-LLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGA 271 HSP 2 Score: 58.151 bits (139), Expect = 7.274e-9 Identity = 42/148 (28.38%), Postives = 65/148 (43.92%), Query Frame = 1
Query: 169 TALHLAAYIGNSNIADILIKYGIDVNSK-DVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHV-----LGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARG 594
T LH A+ ++ D L+ G DVN++ TPL A ++ L+ GAD D++ H+ +++ + +L +V L I+ D GRT+L A G V LL SI +D G P+HW +G
Sbjct: 111 TGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKG 258 HSP 3 Score: 51.6026 bits (122), Expect = 6.602e-7 Identity = 31/98 (31.63%), Postives = 46/98 (46.94%), Query Frame = 1
Query: 136 LDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPH 429
LD++ +D +T+L AAY G+S L+K+G + D G TPL +VL LI GAD + + F + N+V L+ L H
Sbjct: 205 LDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIAQEMNTVYSLREALTH 302 HSP 4 Score: 50.0618 bits (118), Expect = 2.445e-6 Identity = 62/228 (27.19%), Postives = 89/228 (39.04%), Query Frame = 1
Query: 1825 DCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGR---TALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGD 2499
+ I G + ND S + + L H A+ + ++++LV R+G T LH AA G+ V FLL GA PT D D +N LH SV++ N M++ L N V G D+D +D GRTSL A G V LL A I++ D G + G ++L LI A+ + + D
Sbjct: 91 EMIHGKLLEVNNDGDSTEHITGL-HWASINNRLSVVDFLVS----QGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTD-DQGFNLLHL-----SVNSSNIMLVLYVLFN------------------VVSKGL-----------LDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTD 278
BLAST of Ankyrin repeat domain 28b vs. Ensembl Yeast
Match: AKR2 (Ankyrin repeat-containing protein; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; possibly involved in constitutive endocytosis of Ste3p; AKR2 has a paralog, AKR1, that arose from the whole genome duplication [Source:SGD;Acc:S000005560]) HSP 1 Score: 58.151 bits (139), Expect = 7.784e-9 Identity = 57/215 (26.51%), Postives = 94/215 (43.72%), Query Frame = 1
Query: 1813 EAKMDCIKGHVDSSQNDYQS-KDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLL 2454
+ + +K V+S D + + D LS +H A + + +L+ + N G TALH AA G+ V LL GA PT D+ N +H++ ++ + ++ V N +DS D + R+PL+ A G T E L+ G+ V D G +LH A G + L+ A + + ++ F +A G K+L
Sbjct: 60 DGDLKVVKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLL-LRGANPNQAAGPGGATALHWAARYGNIYIVDLLLKHGADPTLKDEQGL-NIMHFSVYSSNILLVVYVLYFVVNNNDNVDIDSKDNNNRTPLLWAAYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVICDLILSGANFYERNNQKQDCFDLAEGMGTKSLF 272 HSP 2 Score: 52.7582 bits (125), Expect = 2.972e-7 Identity = 48/184 (26.09%), Postives = 85/184 (46.20%), Query Frame = 1
Query: 208 IADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWN-RAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILL------DNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAEL 738
+ D++ +D+N+ ++ ++ L AC +N +V L+ GA+ N A H A + ++ + L+L H + D G +H +V + +I +V +L ++N I + D N P+ WAA +GD + LLL + + D + ALH A G ++ LI GA
Sbjct: 66 VKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLLLRGANPNQAAGPGGATALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNVDIDSKDNNNRTPLLWAAYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVICDLILSGANF 249
BLAST of Ankyrin repeat domain 28b vs. Ensembl Yeast
Match: PHO81 (Cyclin-dependent kinase (CDK) inhibitor; regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003465]) HSP 1 Score: 56.9954 bits (136), Expect = 1.738e-8 Identity = 77/303 (25.41%), Postives = 119/303 (39.27%), Query Frame = 1
Query: 2095 NALHYAAS---QGSVDALNEMILSVKL--ENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNG--ADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLH--CAIDSKCDETLECVLKI-----ANNDLINTPDKY-----------SWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLE 2928
N H AAS + + L+E + + KL E + L+++ D H R PL A + G L++ DVD D+ +T L A N H++ V LL G NA S K +L N +++ Q D PL+ A + + ++L E+ + + N C K + T C L I + LI +Y WTPIFYAV + + +L+ HNA ++ +D NG +P+ A E + LN LL+
Sbjct: 382 NVFHEAASCPEKSRLFILDEALTTSKLSKETVQKLLNAQDIHSRVPLHYAAELGKLEFVHSLLITNLLEDVDPIDSDSKTPLVLAITNNHIDVVRDLLTIG---------GANA-----SPIEKPILDYSKNVISSTKVQFD------------------------PLNVACKFNNHDAAKLLLEIRSKQNADNAKNKSSQHLCQPLFKKNSTGLCTLHIVAKIGGDPQLIQLLIRYGADPNEIDGFNKWTPIFYAVRSGHSEVITELLKHNARLDIEDDNGHSPLFYALWESHVDVLNALLQ 646 HSP 2 Score: 49.2914 bits (116), Expect = 4.821e-6 Identity = 65/253 (25.69%), Postives = 106/253 (41.90%), Query Frame = 1
Query: 1063 GKSPLHFAASRNQLK--QAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLL---------------EYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINN-------------LDDDGLGRNLVH-CAVAGGSLKCLETIIRLGGDIHHEDNL-KQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILS-PIN-INDHLSFIENNIMDNT 1719
+ PLH+AA +L+ ++L+ DV+ D TPL +A + V+ LL +Y N + + P++VA F N KLL + K + +N + G +H A GG + ++ +IR G D + D K TP+ AV+ + + L+K A +D+ED+ + Y A++ D+L L N+ S P+N IN S N +D T
Sbjct: 424 SRVPLHYAAELGKLEFVHSLLITNLLEDVDPIDSDSKTPLVLAITNNHIDVVRDLLTIGGANASPIEKPILDYSKNVISSTKVQFDPLNVACKFNNHDAA-KLLLEIRSKQNADNAKNKSSQHLCQPLFKKNSTGLCTLHIVAKIGGDPQLIQLLIRYGADPNEIDGFNKWTPIFYAVRSGHSEVITELLKHNARLDIEDDNGHSPLFY-ALWESHVDVLNALLQRPLNLPSAPLNEINSQSSTQRLNTIDLT 674 HSP 3 Score: 48.521 bits (114), Expect = 6.935e-6 Identity = 64/248 (25.81%), Postives = 114/248 (45.97%), Query Frame = 1
Query: 538 ISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIR--DKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHL----KSNSHQ--DLIEEIK-----DNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSE-NGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKAN 1239
++A D + P+H+AA G LE ++ LL + ++ D D T L +A HID+V L+ G ++ I++ ++S+ + + L K N+H L+ EI+ DN + L L +N GL +LHI++++ Q + LL+ YGA+PN + N +P+ +A + L+K A ++I+DD+ ++PL A + + LL+ N
Sbjct: 417 LNAQDIHSRVPLHYAAELGKLEFVHSLLITNLLEDVDPIDSDSKTPLVLAITNNHIDVVRDLLTIGG--------------ANASPIEKPILDYSKNVISSTKVQFDPLNVACKFNNHDAAKLLLEIRSKQNADNAKNKSSQHLCQPLFKKNSTGLCTLHIVAKIGGDPQLIQLLIRYGADPNEIDGFNKWTPIFYAVRSGHSEVITELLKHNARLDIEDDNGHSPLFYALWESHVDVLNALLQRPLN 650
BLAST of Ankyrin repeat domain 28b vs. Ensembl Yeast
Match: GDE1 (Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes [Source:SGD;Acc:S000006031]) HSP 1 Score: 53.9138 bits (128), Expect = 1.515e-7 Identity = 43/137 (31.39%), Postives = 65/137 (47.45%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYG-IDVNSKDVNGV--TPLFKACASNSHNVLTVLISSGADTNCRDN--KWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKIL 519
L LD N+K + LHLA N + +L+ D+N +D N + TPL+ AC N L+ +GAD R+ W F V AA D +KL++ + +I D G T + HAV GH+ + ++
Sbjct: 492 LLQSLDPNVK-LKSSSLLHLATEWNNYPLLHVLLSSKRFDINYQD-NELHETPLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIF-VAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIADMV 625 HSP 2 Score: 53.1434 bits (126), Expect = 3.006e-7 Identity = 44/178 (24.72%), Postives = 85/178 (47.75%), Query Frame = 1
Query: 1153 DDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKL------LDNVTLKTHINNLDDDGL--GRNLVHCAVAGGSLKCLETIIRLGG-DIHHEDN-LKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI 1656
D+++ TPLH +C++G + +++++ + E +PI +AF + + L T + + +LD + +L+H A + L ++ DI+++DN L +TPL+LA +LN F L+ GA +++ ++ + A DI++LL N AN
Sbjct: 425 DNYKRTPLHYSCQYGLSEVTKLIIKLMKEWNIWNE---IPIDDVSAFGDAESLTPLHLCVLGAHPKTTEVLLQSLDPNVKLKSSSLLHLATEWNNYPLLHVLLSSKRFDINYQDNELHETPLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIFVAAAEGFTDIVKLLIANNANF 599
BLAST of Ankyrin repeat domain 28b vs. Ensembl Nematostella
Match: EDO49485 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG84]) HSP 1 Score: 94.7449 bits (234), Expect = 1.198e-21 Identity = 77/267 (28.84%), Postives = 115/267 (43.07%), Query Frame = 1
Query: 1264 MLPIHVAT--AFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQND---YQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLL 2049
M P+H+A F C C L V + NN R +HCA G++ CLE ++ GD + D L + PLH A NF L+ G++++ D C +HYAA + + + L N N + K+ VH+A +G+ L +EM+ +D S ND S ++ +HLAA+HGH L L++ F N + +D GRT L LA++QGH V+ LL
Sbjct: 1 MQPLHLACLGGFTEC-CKKLLFYGVDVNAKDNN------DRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGNA--------------------SKRDKQGYSAVHYASANGH----KLAIEML------------LDVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSF--NDLEVRDDRGRTPLDLASFQGHVECVECLL 222 HSP 2 Score: 88.9669 bits (219), Expect = 1.050e-19 Identity = 66/207 (31.88%), Postives = 104/207 (50.24%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHN-SVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLD---NNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGA 732
L+ +DVN KD D+T LH AA GN N ++L+ D N D G PL A + + L+++G++ N D K H AA + C++ +L + + D G +A+H+A ANGH +++LLD N+ +S V P+H AA G L +L+ + ++ +RD T L +AS GH++ V L+ A
Sbjct: 20 LFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGNASKRDKQGYSAVHYASANGHKLAIEMLLDVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPLDLASFQGHVECVECLLNHNA 226 HSP 3 Score: 82.4185 bits (202), Expect = 1.842e-17 Identity = 72/242 (29.75%), Postives = 110/242 (45.45%), Query Frame = 1
Query: 2215 PLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNL--LMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRG-HTNCIE-MLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLIN-TPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLL 2925
PL +A G T +KL+ G DV+ KD RT LH A +G+V C++LL+ D GRN + A AGH N +M L+ +N + K D TPLH+AA+ C+E +L + K + +H A + +E +L ++ NDL+N + TP+ A + ALE LI D+ +D G TP+ +A+ +G + C+ LL
Sbjct: 3 PLHLACLGGFTECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYA--AGHTNFRCVMSLVTAGSN-------VNKP-------------DTKACTPLHYAAASDLDAKCVEHLLRNRGNASKRDKQGYSAVHYASANGHKLAIEMLLDVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPLDLASFQGHVECVECLL 222 HSP 4 Score: 79.7221 bits (195), Expect = 1.575e-16 Identity = 50/141 (35.46%), Postives = 71/141 (50.35%), Query Frame = 1
Query: 175 LHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANG-HIEVVKILLDNNTSISASDKNGVRPIHWAAARG 594
LHLA G + L+ YG+DVN+KD N TPL A S + N L +L+S D NC D H A H + C+ ++ +N D+ T LH+A A+ + V+ LL N + S DK G +H+A+A G
Sbjct: 4 LHLACLGGFTECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGNASKRDKQGYSAVHYASANG 144 HSP 5 Score: 68.5514 bits (166), Expect = 1.107e-12 Identity = 69/217 (31.80%), Postives = 103/217 (47.47%), Query Frame = 1
Query: 1744 PVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDV-LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQG-HAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVK---LENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNA 2379
P+H A SGN + + LL+ S D+ D + + +H AA GH+ + + + + V+ D T LH AA A V+ LL + DK Y +A+HYA++ G A+ EM+L V L NR S + +PL +A +GH E LI + D++++D GRT L A+ GHVECV+ LL+ NA
Sbjct: 36 PLHCAACSGNVNCLELLM-----------------SQAGDFNCIDKLGRNPLHYAA--GHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGNASKRDKQGY-SAVHYASANGHKLAI-EMLLDVSANDLLNRSSGSPCV-----TPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPLDLASFQGHVECVECLLNHNA 226 HSP 6 Score: 67.0106 bits (162), Expect = 3.456e-12 Identity = 56/190 (29.47%), Postives = 90/190 (47.37%), Query Frame = 1
Query: 940 LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYE-KFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLV---HCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLA 1497
+N+++ T LH + N C++LL++ + N + + G++PLH+AA + + L+ A ++VN D TPLH A + K V+ LL + NA + G +H A+A HKL + L N+L + G V H A G LE +I+ D+ D+ +TPL LA
Sbjct: 26 VNAKDNNDRTPLHCAACSGNV-NCLELLMSQAGDFNCIDKLGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGNASKRDKQGYSAVHYASANG-----HKLAIEMLLDVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPLDLA 209 HSP 7 Score: 67.0106 bits (162), Expect = 3.622e-12 Identity = 51/171 (29.82%), Postives = 81/171 (47.37%), Query Frame = 1
Query: 265 VTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGX-XXXXXXXXXXXXXMNIRDKDDYTALHIASAMGH---IDIVI-----RLIEKGAELDCVT 750
+ PL AC L+ G D N +DN H A +V+CL+L++ N D GR LH+A + + V L+ ++++ D P+H+AAA + + LL N N + RDK Y+A+H ASA GH I++++ L+ + + CVT
Sbjct: 1 MQPLHLACLGGFTECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGNASKRDKQGYSAVHYASANGHKLAIEMLLDVSANDLLNRSSGSPCVT 171 HSP 8 Score: 59.3066 bits (142), Expect = 1.299e-9 Identity = 59/210 (28.10%), Postives = 89/210 (42.38%), Query Frame = 1
Query: 2566 LTPLHFAASRGHTNCIE-MLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPI-MIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI 3189
+ PLH A G T C + +L+ D N T LHCA S LE ++ A + N DK P+ YA N + L+ +++N D CTP+ AA + C+ LL + DK + +HYA + I +L + L S + TP HLAAF+ L LI DL +++ + + P+
Sbjct: 1 MQPLHLACLGGFTECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGD--FNCIDKLGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLR-NRGNASKRDKQGYSAVHYASANGH-KLAIEMLLDVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPL 206 HSP 9 Score: 58.9214 bits (141), Expect = 1.958e-9 Identity = 64/239 (26.78%), Postives = 113/239 (47.28%), Query Frame = 1
Query: 562 VRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFV----LIKERLESIL------NSRNYQGLTSLHILSQMDNAHQ-CVDLLLAYGANPNLLSENGK---SPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKA 1236
++P+H A G E LL ++N +D +D T LH A+ G+++ + L+ + + +C+ G N LH A+ + + V L+ A SN ++ + H+ L + +E +L + R+ QG +++H S N H+ +++LL AN L +G +PLH AA +LIK+ D+ ++DD TPL +A G+ + V+ LL + A
Sbjct: 1 MQPLHLACLGGFTECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYAAGHTNFRCVMSLVTA-----------GSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGNASKRDKQGYSAVHYASA--NGHKLAIEMLLDVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPLDLASFQGHVECVECLLNHNA 226 HSP 10 Score: 51.9878 bits (123), Expect = 3.950e-7 Identity = 55/196 (28.06%), Postives = 78/196 (39.80%), Query Frame = 1
Query: 1006 QCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFK-NCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQ-------TPLHLAVKLNNFMITRILIKLGASIDVEDE 1569
+C LL YG + N N ++PLH AA + LL+ D N D PLH A + V L+ +N P+H A A + C+ LL N N D G + VH A A G +E ++ D+ D L + TPLHLA + +LIK ++V D+
Sbjct: 14 ECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRG-----NASKRDKQGYSAVHYASANGHKLAIEMLL----DVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDD 200 HSP 11 Score: 51.2174 bits (121), Expect = 6.561e-7 Identity = 59/231 (25.54%), Postives = 92/231 (39.83%), Query Frame = 1
Query: 1894 IHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVK-----------------------------LENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTS-------LHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVA 2478
+HLA G +E L +F V+ +D + RT LH AA G+ ++ L+S +DK N LHYAA + + ++ + L NR + D+ S + A NGH E L+ DV D R+S LH A +GH +++L+ +E+ D RGR +A+ GH + L+N+ A
Sbjct: 4 LHLACLGGFTECCKKL--LFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDK-LGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGN-ASKRDKQGYSAVHYASANGHKLAIEMLL----DVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPLDLASFQGHVECVECLLNHNA 226 HSP 12 Score: 47.7506 bits (112), Expect = 9.701e-6 Identity = 63/294 (21.43%), Postives = 107/294 (36.39%), Query Frame = 1
Query: 1072 PLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVK--LNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDV-LSLIHLAAYHGHSEILNYLV 1944
PLH A + L+ DVN +D+++ TPLH A G +++L+ + + G P+H A N +C+ +++ G +++ D TPLH A L+ + +L G + D+ A+HYA+ N + +L D AN L N S G V P+H A G+ + +L++ S ND + +DD + + LA++ GH E + L+
Sbjct: 3 PLHLACLGGFTECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYAAGHTN--------------------------------------FRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRG-NASKRDKQGYSAVHYASA-NGHKLAIEMLLDVSANDLL-----------------NRSSGSPCVTPLHLAAFHGHKPALEVLIK-----------------SFNDLEVRDDRGRTPLDLASFQGHVECVECLL 222
BLAST of Ankyrin repeat domain 28b vs. Ensembl Nematostella
Match: EDO38702 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC57]) HSP 1 Score: 95.5153 bits (236), Expect = 2.504e-20 Identity = 132/517 (25.53%), Postives = 197/517 (38.10%), Query Frame = 1
Query: 964 LTSLHILSQMDNAHQCVDL---LLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKA----------KADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYV 2475
+T LH+ +H C+ + L+ GA+ L E +PLHFA L A LL A V QD E T LH+A G+ ++ LE AN E H C+ ++ LK +++ + + R ++ + C IIR I D K TPL +A + N+ R L++ GA I +D N + R + L + + I D+ L + G + +IL+L + ++ +D G S+ND ++ IH AA G + L++ I++ +D + T LHLAA GHA VK LL G G++DA N + + PL A G A L+ A VD D T LH A+ GHVE V LLL A I L D GRN +A + HK + + +I++V
Sbjct: 5 MTPLHVAC----SHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLFVAAELRGGWSTVSKMVTDQDREEQTALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVAR-ECIFVMIKVSKLK-YLSFCKSEKIKREILLYFFDVVIIICY--IIRFRACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKD------------INDRNSVFRAAAEGCMETLEAALEHQKPVW---TICDDVCLNG----------LVGGSNKLILVLRI-SSQLLLD--NGACIDSKNDED-----ITPIHYAAKFGRVRTVCALLK-RDPAIINDEDGASNTPLHLAALHGHAAVVKELLYRG---------------------GAIDARNATLWT-------------------PLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEVAVAIIDHV 439 HSP 2 Score: 59.3066 bits (142), Expect = 5.909e-9 Identity = 100/432 (23.15%), Postives = 172/432 (39.81%), Query Frame = 1
Query: 1474 KQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPN-----EAK-----------MDCIKGHVDSSQNDYQS--KDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIM-----------NGADVDLKDTYGRTSLHRATANGHVECVDLLLDCN-AKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIF----------INELKSMWFDQD---------YLTPLHFAASRGHTNCIEML 2622
+ TPLH+A + + L++ GA + DE +H+A M G + +LLF + S + + D ++ +H AV G+ D L LE N E+K +CI + S+ Y S K + + L + I+ Y+++ + + +D+ T L +AA + H V+ LL GA A D + N++ AA++G ++ L LE++K + D+ NG + KLI+ NGA +D K+ T +H A G V V LL + A I D ++AA GH ++ +L+ Y G ++ ++ + E+ ++ D+D TPLH A+ GH +++L
Sbjct: 4 QMTPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLG-VAKLLF-------VAAELRGGWSTVSKMVTDQD---REEQTALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKVSKLKYLSFCKSEKIKREILLYFFDVVIIICYIIRF--RACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDR-NSVFRAAAEGCMETLE-----AALEHQKPVWTICDD--------VCLNGLVGGSNKLILVLRISSQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLHLAALHGHAAVVKELL------YRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLL 402 HSP 3 Score: 58.5362 bits (140), Expect = 1.275e-8 Identity = 66/245 (26.94%), Postives = 106/245 (43.27%), Query Frame = 1
Query: 142 VNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVL-------------------------------------TVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDG--RTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQG 759
+ +D T L +AA + + L+++G D+ +KD+N +F+A A L +L+ +GA + ++++ H A V + +L I I D DG T LH A +GH VVK LL +I A + P+ AAARG +E+ N+LLD DA ++ DK T LH+AS GH+++V L+ + A + + G
Sbjct: 173 IECRDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDRNSVFRAAAEGCMETLEAALEHQKPVWTICDDVCLNGLVGGSNKLILVLRISSQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAI-INDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAG 416 HSP 4 Score: 57.7658 bits (138), Expect = 2.159e-8 Identity = 97/428 (22.66%), Postives = 158/428 (36.92%), Query Frame = 1
Query: 2212 SPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLL----------DCNAKIELFDFRGRNAFYMAASAGHKNL----LMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVD----------------------------------KSNQNI--LHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANL---ALKTSLNLSPKKGYVINLK 3336
+PL +A +G A+ L+ GAD+ D T LH A G++ LL + + D + A ++A GH +L L K N A K + K+ + E + L L F S E+L D + + F C +EC DK TP+ A ++V+ + L+ H ADI +D+N + AA EG + L LE Q W + D K++++I +HYA + +L++ P +IN D TP HLAA + + L+ G + +N P+ C + A +E+ A + D+P + A T L+L+ ++G+V +K
Sbjct: 6 TPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLFVAAELRGGWSTVSKMVTDQDREEQTALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTI-VVARECIFVMIKVSKLKYLSFCKSEKIKR--EILLYFFDVVIIICYIIRFRAC---------IEC------------RDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDRNSVFRAAAEGCMETLEAALEHQKPVWTICDDVCLNGLVGGSNKLILVLRISSQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDP---AIINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPL-DC---AAARGMVEV--ANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVK 400 HSP 5 Score: 56.6102 bits (135), Expect = 4.307e-8 Identity = 37/129 (28.68%), Postives = 62/129 (48.06%), Query Frame = 1
Query: 142 VNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDN 528
+N +D T LHLAA G++ + L+ G +++++ TPL A A V +L+ A + D H+ + V+ +KL+L I +TDS GR L A+ + H EV ++D+
Sbjct: 310 INDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEVAVAIIDH 438 HSP 6 Score: 56.225 bits (134), Expect = 5.579e-8 Identity = 102/446 (22.87%), Postives = 173/446 (38.79%), Query Frame = 1
Query: 169 TALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVL-----ISSGADTNCR-----DNKWNRAFHVCAAHNSVDCLKLILPHVLGIN-ITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALN------------------------------SSHLFLEH---LKSNSHQDLIEEIKDNHFVLIK------ERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINN 1356
T LH+A G +A L++ G D+ S D +TPL AC + V +L + G T + D + A H+ D KL L +N + +S +T V V I + +S ++ + I+ ++ A + RDKD T L IA+ H+D V L++ GA+ + + N + +E L AL SS L L++ + S + +D+ F ++ +R +I+N + T LH L+ + V LL G + + +PL AA+R ++ A +L+ A V+ D + TPLH+A R G+ + V++LL KAN + G + +A + ++D+V K + N
Sbjct: 6 TPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLFVAAELRGGWSTVSKMVTDQDREEQTALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKVSKLKYLSFCKSEKIKREILLYFFDVVIIICYIIRFRACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHGAD---IAAKDINDRNSVFRAAAEGCMETLEAALEHQKPVWTICDDVCLNGLVGGSNKLILVLRISSQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLH-LAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEVAVAIIDHVDWKQAMRN 447
BLAST of Ankyrin repeat domain 28b vs. Ensembl Nematostella
Match: EDO37520 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFL9]) HSP 1 Score: 95.9005 bits (237), Expect = 7.993e-20 Identity = 110/442 (24.89%), Postives = 184/442 (41.63%), Query Frame = 1
Query: 163 DQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQ-DLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHEN-----TPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDN 1470
+ TALH AA N+ + +L + V+ D N TP F A ++ N+L +L GA+ N ++ A + DC +L+ G + LH A GH+E VK LL++ S A G P+ AA G + ++ +L + A + R L A+A GH+ V L + G +CV + + + + +E + ++ H+ S Q D++ I ++ ++ L +Y G+ LH + + N+ + + L YG +P LS + + ++ K NI D E LH+A R G + LLEY A V G +HVA + G + L+ K +N+ D +G+ H AV + L+ + +LG +IH ED+
Sbjct: 803 NMTALHFAASTSNTGVIGLLANHFSTVDCLDRNSRTPAFIAASTGQKNILAILFQKGANLFHVTNSLSKKHQQRAKNPVKDCKRLMC------------GYSLLHAAAQGGHVETVKFLLNHKLSKDAESGAGNTPMQIAAQYGRVSVMEVLHKHGAPCDPR------PLRSAAAGGHLPAVRFLHQAGVSDECVPCKYSISPSYMKQRVGKLVDDEYLWRCETAL----HIASAMEQPDIVSYILRSN--------DTALTCYDYLGMRPLH-KAVVYNSIKSLKAFLEYGVSP--LSRCAPAEVLSTYPEDKYK------------NIADYFEPCICRYNALHLAARHGRVNMIATLLEYGAKTGVFDACGSQAVHVAACYDQVGVLSLLV--AEYKVDVNS--RDLIGKTPFHYAVKCKAAGALKRLFKLGANIHAEDD 1195
BLAST of Ankyrin repeat domain 28b vs. Ensembl Nematostella
Match: EDO39113 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB41]) HSP 1 Score: 76.2554 bits (186), Expect = 1.095e-15 Identity = 52/168 (30.95%), Postives = 96/168 (57.14%), Query Frame = 1
Query: 238 DVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFH--VCAAH-NSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILL-DNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKG 729
++N+ D +G +PL A +N +++ +L+ +GAD + R + + +CAA N+++ +++L +NIT+ G+TALHHA GH ++V++LL D ++ D++ +H AA G I+ LL AN+ +D D +TA H+A+ G +++ L+ G
Sbjct: 21 NLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLRTG 188 HSP 2 Score: 56.9954 bits (136), Expect = 4.721e-9 Identity = 39/116 (33.62%), Postives = 60/116 (51.72%), Query Frame = 1
Query: 79 FNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYG-IDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLIL 423
FN+I + R L DVNI + Y QTALH A G+S + ++L++ G +DVN D + T L A S+ ++ L+ GA+ +DN AFH+ A + L+ +L
Sbjct: 75 FNAI-----ESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLL 185 HSP 3 Score: 52.7582 bits (125), Expect = 1.109e-7 Identity = 45/180 (25.00%), Postives = 77/180 (42.78%), Query Frame = 1
Query: 2092 WNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLL-DCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYE 2628
++ LHYA + VD + +M+L + + S + P++ A + + L+ GADV++ + YG+T+LH AT GH + V+LLL D + + D + ++AA G ++ L+ AN + D D T H AA G ++ L
Sbjct: 30 FSPLHYATTTNHVDIV-QMLLDAGAD--VDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAK--------------------DNDGFTAFHLAAREGEEEVLQTLLR 186 HSP 4 Score: 52.373 bits (124), Expect = 1.528e-7 Identity = 48/188 (25.53%), Postives = 85/188 (45.21%), Query Frame = 1
Query: 994 DNAHQCVDLLLAYG-ANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDD---HENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLG 1545
D CV LL N N L +G SPLH+A + N + +L+ A ADV+++ P+ A +F + ++LL A+ + G +H AT + + LL + + ++ + D+ +H A GS ++T++ G +I +DN T HLA + + + L++ G
Sbjct: 5 DGRKDCVRKLLRGNLTNLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNT----TSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLRTG 188
BLAST of Ankyrin repeat domain 28b vs. Ensembl Nematostella
Match: EDO42780 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0Q6]) HSP 1 Score: 74.7146 bits (182), Expect = 4.081e-15 Identity = 48/141 (34.04%), Postives = 70/141 (49.65%), Query Frame = 1
Query: 169 TALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLG--INITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAA 585
T L +A GN L G +N++D G TPL A ++ + L++ GAD+ DN H ++S + L+L H+ IN D +G TALH A +G E VK+L+D++ I A D G +HWAA
Sbjct: 50 TPLFVAVSTGNLECVQFLATSGASLNTRDNLGRTPLALAAYQGWNDGVYYLLAVGADSTIVDNCGRLPLHAATYYSSGRTVGLLLQHLPSDHINKQDGEGMTALHWAAYHGRAEHVKLLIDHDAEIVARDTEGKTALHWAA 190 HSP 2 Score: 58.5362 bits (140), Expect = 1.867e-9 Identity = 44/154 (28.57%), Postives = 73/154 (47.40%), Query Frame = 1
Query: 1051 LSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNN 1512
L+ G +PL A S L+ L + A +N +D+ TPL +A G+ V LL A++ + G LP+H AT + + + LL ++ HIN DG G +H A G + ++ +I +I D +T LH A ++++
Sbjct: 44 LNSEGMTPLFVAVSTGNLECVQFLATSGASLNTRDNLGRTPLALAAYQGWNDGVYYLLAVGADSTIVDNCGRLPLHAATYYSSGRTVGLLLQHLP-SDHINK--QDGEGMTALHWAAYHGRAEHVKLLIDHDAEIVARDTEGKTALHWAAQVSH 194 HSP 3 Score: 52.7582 bits (125), Expect = 1.412e-7 Identity = 53/191 (27.75%), Postives = 77/191 (40.31%), Query Frame = 1
Query: 1885 LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLI--MNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNL 2451
++ + +A G+ E + +L S ++T+D GRT L LAAYQG V +LL+ GA T VD R PL A RT L+ + ++ +D G T+LH A +G E V LL+D +A+I D G+ A + AA H L
Sbjct: 49 MTPLFVAVSTGNLECVQFLAT--SGASLNTRDNLGRTPLALAAYQGWNDGVYYLLAVGADSTIVDNC----------------------------------------GRLPLHAATYYSSGRTVGLLLQHLPSDHINKQDGEGMTALHWAAYHGRAEHVKLLIDHDAEIVARDTEGKTALHWAAQVSHDGL 197 HSP 4 Score: 50.8322 bits (120), Expect = 6.743e-7 Identity = 50/196 (25.51%), Postives = 83/196 (42.35%), Query Frame = 1
Query: 2101 LHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEM--KSTNGFMTFLHCA 2682
+H G + AL E + + K L+++L+ +PL +AV G+ + L +GA ++ +D GRT L A G + V LL A + D GR + A + L+ ++ + D I K D + +T LH+AA G +++L + E+ + T G T LH A
Sbjct: 18 IHELVHAGDITALKE-----EFQRDKGLIEALNSEGMTPLFVAVSTGNLECVQFLATSGASLNTRDNLGRTPLALAAYQGWNDGVYYLLAVGADSTIVDNCGRLPLHAATYYSSGRTVGLLLQHLPS-----DHINKQ-------------DGEGMTALHWAAYHGRAEHVKLLIDHDAEIVARDTEG-KTALHWA 189 HSP 5 Score: 48.521 bits (114), Expect = 3.519e-6 Identity = 34/123 (27.64%), Postives = 58/123 (47.15%), Query Frame = 1
Query: 922 ERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGED--GMLPIHVA 1284
+R + ++ + N +G+T L + N +CV L GA+ N G++PL AA + L+ AD I D+ PLH A + + V +LL++ + + +D GM +H A
Sbjct: 35 QRDKGLIEALNSEGMTPLFVAVSTGNL-ECVQFLATSGASLNTRDNLGRTPLALAAYQGWNDGVYYLLAVGADSTIVDNCGRLPLHAATYYSSGRTVGLLLQHLPSDHINKQDGEGMTALHWA 156
BLAST of Ankyrin repeat domain 28b vs. Ensembl Medaka
Match: ankrd28b (ankyrin repeat domain 28 [Source:NCBI gene;Acc:101159131]) HSP 1 Score: 503.827 bits (1296), Expect = 1.406e-158 Identity = 346/1064 (32.52%), Postives = 537/1064 (50.47%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDV---LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMF 3252
P L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH+E+V++LL ++I+A DK R IHWAA G +E++ LL + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI+ +H+ N N +G LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I+ A+++ +D + NTPLHIA R+G+E + L+ +A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D+ +TPLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I DN VH+A G+ L LE++ +E +D + +++S D + DV +S +HLAAYHGH + + LVQ + ++ GRT L LAA++GH V L++ GA D +H AA+ G + L +I + L+ S VD D + ++PLM+AV +GHT L+ GA V+ KD +GRT+LHR GH EC++ LL NA + D RGR ++AA+ GH +L L+ H +E + D TPLH+A GH C+E+L E K+ + LHCA+ + E ++ ++N D + TP+ A D+V L+ L+ HNA +N D G +P+M+AA+ G + + LL+ + D LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA + + P ++C N +DC+ + LA M
Sbjct: 10 PPLLKAIFNVDPDEVRSLIFKKEDVNAQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDNKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVRCAEALVPLLSNVNVSDRAGRTALHHAAFSGHLEMVRLLLSRGSNINAFDKKDRRAIHWAAYMGHIEVVKLLASHGAEVTCKDKKSYTPLHAAASSGMISVVKFLLDLGVDINEPNAYGNTPLHVACYNGQDVVVNELIEC--GAHV---------------------------------NQVNEKGFAPLHFTAASRHGALCLELLVCNGADVNIKSKDGKTPLHMTAIHGRFSRSQAIIENGAEIDCEDKNGNTPLHIAARYGHELLINTLITNRADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNRKDSFGRTPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAAASDTDGKCLEYLLRNDAN---------------PGIRDNQGYNA-----VHYASAYGHR----LCLELIASETPLDVL---METSGTDILNDSDVRAPVSPLHLAAYHGHHQAMEVLVQSLLD--LDVRNSQGRTPLDLAAFKGHVECVDVLINQGASILVKDFTLKRTPIHAAATNGHSECLRLLIGNADLQ---SAVDIQDGNGQTPLMLAVLSGHTDCVYSLLNKGASVEAKDKWGRTALHRGAVTGHEECMEALLQHNASFLVRDCRGRTPVHLAAACGHIGVLGGLL-------HAAQSVET---------LPVLTDSHGYTPLHWACYNGHDTCVEVLLEQEVFHKAEGNPFSPLHCAVIRDNEGAAEMLIDTLGPTIVNAKDGKNRTPLHAAAFTDHVECLQLLLSHNAQVNTVDAAGKSPLMMAAENGQTNAVELLVSSAKADLTIQDAVKNTALHLACSKGHETSALLILEKI-SDRNLINATNAALQTPLHVAARNGLTVVVQELLAKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 984 HSP 2 Score: 90.1225 bits (222), Expect = 1.051e-17 Identity = 111/418 (26.56%), Postives = 170/418 (40.67%), Query Frame = 1
Query: 2173 RKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLL----DCNAK-----------------------------IELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTN-GFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPI--MIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKG 3318
+K V++ D KR+PL A G E LI++GA V+ KD T LHRA A+ E V +LL D NA+ + + D GR A + AA +GH ++ L++ +N IN FD+ +H+AA GH +++L E+ + T LH A S ++ +L + + IN P+ Y TP+ A ++ + +LI A +N + G P+ A++ G L CL LL+ C + K + LH S I+E I+ D N TP H+AA L +N LIT AD + P+ S SDC L++ F D+P + +T L+ + G
Sbjct: 30 KKEDVNAQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDNKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVRCAEALVPLLSNVNVSDRAGRTALHHAAFSGHLEMVRLLLSRGSN---------------INA-----FDKKDRRAIHWAAYMGHIEVVKLLASHGAEVTCKDKKSYTPLHAAASSGMISVVKFLLDLGVD--INEPNAYGNTPLHVACYNGQDVVVNELIECGAHVNQVNEKGFAPLHFTAASRHGAL-CLELLV-CNGADVNIKSKDGKTPLHMTAIHGRFSRSQAIIEN----GAEIDCEDKNGNTPLHIAARYGHELLINTLITNRADTAKRGIHGMFPL-HLAALSGFSDCCRKLLSSGF-DIDTPDDFG-RTCLHAAAAGG 416
BLAST of Ankyrin repeat domain 28b vs. Ensembl Medaka
Match: ankrd28b (ankyrin repeat domain 28 [Source:NCBI gene;Acc:101159131]) HSP 1 Score: 488.034 bits (1255), Expect = 9.392e-153 Identity = 337/1032 (32.66%), Postives = 523/1032 (50.68%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDV---LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADL 3156
P L +I D D +R ++ K DVN +D +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS S + VL+ AD N RD W H+ AA+ +V C + ++P + +N++D GRTALHHA +GH+E+V++LL ++I+A DK R IHWAA G +E++ LL + A + +DK YT LH A++ G I +V L++ G +++ GN LH+A N +V ELI+ +H+ N N +G LH + + C++LL+ GA+ N+ S++GK+PLH A + ++ +I+ A+++ +D + NTPLHIA R+G+E + L+ +A+ G GM P+H+A C KLL + I+ DD GR +H A AGG+L+CL ++ G D + +D+ +TPLH A N+ L+ GAS++ DE C +HYAA + +G L L N AN I DN VH+A G+ L LE++ +E +D + +++S D + DV +S +HLAAYHGH + + LVQ + ++ GRT L LAA++GH V L++ GA D +H AA+ G + L +I + L+ S VD D + ++PLM+AV +GHT L+ GA V+ KD +GRT+LHR GH EC++ LL NA + D RGR ++AA+ GH +L G + + + E + D TPLH+A GH C+E+L E K+ + LHCA+ + E ++ ++N D + TP+ A D+V L+ L+ HNA +N D G +P+M+AA+ G + + LL+ + D LH A ++ ++ILEK+ + LIN+ + QTP H+AA N L + + L+ GA +
Sbjct: 10 PPLLKAIFNVDPDEVRSLIFKKEDVNAQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDNKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVRCAEALVPLLSNVNVSDRAGRTALHHAAFSGHLEMVRLLLSRGSNINAFDKKDRRAIHWAAYMGHIEVVKLLASHGAEVTCKDKKSYTPLHAAASSGMISVVKFLLDLGVDINEPNAYGNTPLHVACYNGQDVVVNELIEC--GAHV---------------------------------NQVNEKGFAPLHFTAASRHGALCLELLVCNGADVNIKSKDGKTPLHMTAIHGRFSRSQAIIENGAEIDCEDKNGNTPLHIAARYGHELLINTLITNRADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS---GFDIDTPDD--FGRTCLHAAAAGGNLECLNLLLNTGADFNRKDSFGRTPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAAASDTDGKCLEYLLRNDAN---------------PGIRDNQGYNA-----VHYASAYGHR----LCLELIASETPLDVL---METSGTDILNDSDVRAPVSPLHLAAYHGHHQAMEVLVQSLLD--LDVRNSQGRTPLDLAAFKGHVECVDVLINQGASILVKDFTLKRTPIHAAATNGHSECLRLLIGNADLQ---SAVDIQDGNGQTPLMLAVLSGHTDCVYSLLNKGASVEAKDKWGRTALHRGAVTGHEECMEALLQHNASFLVRDCRGRTPVHLAAACGHIGVL-------------GGLLHAAQSV---ETLPVLTDSHGYTPLHWACYNGHDTCVEVLLEQEVFHKAEGNPFSPLHCAVIRDNEGAAEMLIDTLGPTIVNAKDGKNRTPLHAAAFTDHVECLQLLLSHNAQVNTVDAAGKSPLMMAAENGQTNAVELLVSSAKADLTIQDAVKNTALHLACSKGHETSALLILEKI-SDRNLINATNAALQTPLHVAARNGLTVVVQELLAKGASV 952 HSP 2 Score: 162.54 bits (410), Expect = 4.622e-40 Identity = 229/973 (23.54%), Postives = 401/973 (41.21%), Query Frame = 1
Query: 940 LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANI-------LSPININDH-------LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRS--GRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRK---------------------------SLVDSLDEHKRSPL-MIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRN------------AFYMAASAGHKNLLMKLINYVAN---KYHQG----DFIE-KSH----DIFINELKSMWFDQDYL--TPLHFAASRGHTNCIEMLYELSD-----EMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDL-INTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLL----ECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEK-------------LPCL-----------------KKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALK-TSLNLSPKKGY---------------VINLKEAELEGSIQSSENEYF*AFDIFISKFLYFSEALILKVFCKKNFTF*IF 3480
+N+++ + T LH + + +A + ++LL+ GA N +PLH A + + +L+K ADVN +D + TPLHIA + + L+ +N V+ G +H A AF M +LL ++ ++IN D R +H A G ++ ++ + G ++ +D TPLH A + + L+ LG I+ + Y +H A YN + ++ L + GA++ +P++ L + N D K P+H + G F ++E N A++DC D + N + +H+AA +GH ++N L+ N T R G LHLAA G + + LLS G D D+ LH AA+ G+++ LN ++ + NRK + V+ LDE +PL A + + E L+ N A+ ++D G ++H A+A GH C++L+ L + G + ++AA GH + L+ + + + QG D K H D+ IN+ S+ L TP+H AA+ GH+ C+ +L +D +++ NG + + D CV + N + DK+ T + + +E L+ HNA +D G TP+ +AA G + L LL +TL L D LH+A + D+C ++LE+ L C ++N+ D +TP H AAF L L++ A + + + P++ N + ++ +E+ +++ + D A+K T+L+L+ KG+ +IN A L+ + + + + + L +++ K+FTF +F
Sbjct: 34 VNAQDNEKRTPLHAAAYLGDA-EIIELLILSGARVNAKDNKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVRCAEALVPLLSNVNVSDRAGRTALHHA-AFSGHLEMVRLL--LSRGSNINAFDKKD--RRAIHWAAYMGHIEVVKLLASHGAEVTCKDKKSYTPLHAAASSGMISVVKFLLDLGVDINEPNAYGNTPLHVAC-YNGQDVVVNELIECGAHVNQVNEKGFAPLHFTAASRHGALCLELLVCNGADVNIKSKDGKTPLHMTAIHGRFSRSQAIIE---NGAEIDC----EDKNGN---------TPLHIAARYGHELLINTLI----TNRADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPD-DFGRTCLHAAAAGGNLECLNLLLNTGADFNRKDSFGRTPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAAASDTDGKCLEYLLRNDANPGIRDNQGYNAVHYASAYGHRLCLELIASETPLDVLMETSGTDILNDSDVRAPVSPLHLAAYHGHHQAMEVLVQSLLDLDVRNSQGRTPLDLAAFKGHVECVDVLINQGASILVKDFTLKRTPIHAAATNGHSECLRLLIGNADLQSAVDIQDGNGQTPLMLAVLSGHTD----CVYSLLNKGASVEAKDKWGRTALHRGAVTGHEECMEALLQHNASFLVRDCRGRTPVHLAAACGHIGVLGGLLHAAQSVETLP-VLTDSHGYTPLHWACYNGHDTCVEVLLEQEVFHKAEGNPFSPLHCAVIRDNEGAAEMLIDTLGPTIVNAKDGKNRTPLHAAAFTDHVECLQLLLSHNAQVNTVDAAGKSPLMMAAENGQ-TNAVELLVSS--AKADLTIQDAVKNTALHLACSKGHETSALLILEKISDRNLINATNAALQTPLHVAARN---GLTVVVQELLAKGASVLAVDENGKHFTFSVF 967 HSP 3 Score: 132.494 bits (332), Expect = 9.287e-31 Identity = 193/700 (27.57%), Postives = 313/700 (44.71%), Query Frame = 1
Query: 124 LYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXX-XXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCV-TTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSEN---GKSPLHFAASRNQLKQAVLLIKAKAD----VNIQDDHENTPL-------HIACRF--------------------------GYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILI-KLGASI-DVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVL-SLIHLAAYHGH-SEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKD 2085
+ N +++ +D T LH+AA G+ + + LI D + ++G+ PL A S + L+SSG D + D+ H AA +++CL L+L N DS GRT LH+A AN + + + L+ + S++ D+ G P+H+AAA L LL NDAN IRD Y A+H ASA GH + + LI LD + T G + L+ ++ ++ HL H H +E VL++ L+ L+ RN QG T L L+ +CVD+L+ GA+ +L ++ ++P+H AA+ N + + L+ AD V+IQD + TPL H C + G+E+ ++ LL++ A+ V G P+H+A A + G + LL + L D G +H A G C+E ++ H + +PLH AV +N +LI LG +I + +D +H AA + + L+LL + A + N +D + GK P+ A +G + + LL V S++ D +D V + +HLA GH + L L +I +N+++ + + +T LH+AA G + V+ LL+ GA AVD++
Sbjct: 326 IENGAEIDCEDKNGNTPLHIAARYGHELLINTLITNRADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNRKDSFGRTPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAAASDTDGKCLEYLLRNDANPGIRDNQGYNAVHYASAYGH-RLCLELIASETPLDVLMETSGTDILND----------SDVRAPVSPLHLAAYH----GHHQAME-------VLVQSLLD--LDVRNSQGRTPLD-LAAFKGHVECVDVLINQGAS--ILVKDFTLKRTPIH-AAATNGHSECLRLLIGNADLQSAVDIQDGNGQTPLMLAVLSGHTDCVYSLLNKGASVEAKDKWGRTALHRGAVTGHEECMEALLQHNASFLVRDCRGRTPVHLAAACGHIGVLGGLLHAAQSVETLPVLTDSH-GYTPLHWACYNGHDTCVEVLLE-QEVFHKAEGNPFSPLHCAVIRDNEGAAEMLIDTLGPTIVNAKDGKNRTPLH-AAAFTDHVECLQLLLSHNAQV---------------NTVD--AAGKS---PLMMAAENGQTNAVELL----------------VSSAKADLTIQDAVKNTALHLACSKGHETSALLILEKISDRNLINATNAALQTPLHVAARNGLTVVVQELLAKGASVLAVDEN 958 HSP 4 Score: 90.5077 bits (223), Expect = 7.935e-18 Identity = 111/418 (26.56%), Postives = 170/418 (40.67%), Query Frame = 1
Query: 2173 RKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLL----DCNAK-----------------------------IELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTN-GFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPI--MIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKG 3318
+K V++ D KR+PL A G E LI++GA V+ KD T LHRA A+ E V +LL D NA+ + + D GR A + AA +GH ++ L++ +N IN FD+ +H+AA GH +++L E+ + T LH A S ++ +L + + IN P+ Y TP+ A ++ + +LI A +N + G P+ A++ G L CL LL+ C + K + LH S I+E I+ D N TP H+AA L +N LIT AD + P+ S SDC L++ F D+P + +T L+ + G
Sbjct: 30 KKEDVNAQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDNKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVRCAEALVPLLSNVNVSDRAGRTALHHAAFSGHLEMVRLLLSRGSN---------------INA-----FDKKDRRAIHWAAYMGHIEVVKLLASHGAEVTCKDKKSYTPLHAAASSGMISVVKFLLDLGVD--INEPNAYGNTPLHVACYNGQDVVVNELIECGAHVNQVNEKGFAPLHFTAASRHGAL-CLELLV-CNGADVNIKSKDGKTPLHMTAIHGRFSRSQAIIEN----GAEIDCEDKNGNTPLHIAARYGHELLINTLITNRADTAKRGIHGMFPL-HLAALSGFSDCCRKLLSSGF-DIDTPDDFG-RTCLHAAAAGG 416
BLAST of Ankyrin repeat domain 28b vs. Ensembl Medaka
Match: ankrd52a (serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C [Source:NCBI gene;Acc:101155432]) HSP 1 Score: 479.559 bits (1233), Expect = 2.805e-149 Identity = 342/1081 (31.64%), Postives = 527/1081 (48.75%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDD-------------DGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDH-LSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAM--FSSTD 3264
P L +I +++ ++ L+ DVN D +T LH AA +G+ +I D+LI+ G VN KD +TPL +A AS + +++L+ GA+ N RD W HV +A+ + C + +L H+ +NI D GRTALHHA +G E+VK+LL+ ++SA DK +PIH AA G LE++ LLL + + +DK YT LH A+A GHI+IV L+ GAE+D T GN ALH+A + EL+ NH + N N G T LH+ + N C++LL+ GA+ N S+ GKSPLH AA + ++ +LI+ D++ D + NTPLH+A ++G+E + L+ A+ G GM P+H+A + C KLL + L + ++++ D GR +H A +GG+++CL ++ G D++ D + +TPLH A + T L+ GA ++ D+ C +HY+A G + R N + L + ++ D + + K VH+A GN + LLLEM N + D +S V S +HLAA +GH + L L + + V QD +GR+ L+LAA +GH V+ LL+ GA D W +H AA+ G D L MI L + D+ ++PLM+AV GHT L+ + D +D G T+LHRA GH +CV LL A D +GR + AAS G +L L+ Q + D TPLH+AA +GH +C+E+L EL + T LHCA+ + E +L+ A +IN D +P+ A ++V L+ ++ H A+IN D +G + +M+AA +G + +LL L+D++ LH A A + C ++IL ++ LIN+ ++ Q P HLAA N L + AL++ GA + + + P ++C N +DC+ + L+ M FS D
Sbjct: 10 PPLVQAIFSRNAEEVQLLLHKTEDVNALDQERRTPLHAAACVGDVHIIDLLIESGASVNVKDQVWLTPLHRAAASRNERAVSLLLRRGAEANARDKFWQTPLHVASANRATRCAEALLSHLSNLNIADRTGRTALHHAAQSGFQEMVKLLLNKGANLSAIDKKERQPIHCAAYLGHLEVVKLLLSRSNDKSCKDKLGYTPLHAAAASGHIEIVKYLLRMGAEIDEPNTFGNTALHMACYMGQEAVATELV---------------------------NHGANV--------NQPNKCGYTPLHLAAVSTNGALCLELLVNNGADVNQQSKEGKSPLHMAAIHGRFTRSQILIQNGGDIDCVDKYGNTPLHVAAKYGHELLISTLMTNGADTARRGIHGMFPLHLAVLYGFSDCCRKLLSSGQLYSIVSSMSKEHVLSAGFEINTPDNFGRTCLHAAASGGNVECLNLLLSSGADLNKRDIMGRTPLHYAAANGRYQCTVTLVSAGAEVNESDQTGCTPLHYSAASQAFGRVERHFSGNHQKEEEEEKGSYFCLEHLLDSGADPSMVNSKGYSAVHYAAYHGNKQNLELLLEMSFN-------------ALGDIESSIPV-SPLHLAADNGHWQALRLLTETAA--YVDMQDAAGRSVLYLAAQKGHVRCVEVLLAQGASCFLNDNRLMWTPIHVAAANGHSDCLRMMI---DYGEEGDLTNVADKFGQTPLMLAVLGGHTDCVRFLLERASSPDAQDKRGSTALHRAAVLGHDDCVTALLKHKASPLCRDIQGRTPLHYAASRGQTEILSSLMQAAVAADPQDQLL----------------DNKQYTPLHWAAYKGHEDCLEVLLELKTFIHEEGNPFTPLHCALMNGHCSAAERLLESARVHVINCRDAKGRSPLHAAAFAEDVAGLQLVLRHGAEINAVDNSGRSALMVAADKGHSGTVAILLHRAKADLTLLDENKNTALHLACSKAHEMCALLILGEIHS-PTLINATNSALQMPLHLAARNGLATVVQALLSRGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKPFSQRD 1019
BLAST of Ankyrin repeat domain 28b vs. Ensembl Medaka
Match: ENSORLT00000037670.1 (serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A [Source:NCBI gene;Acc:101168382]) HSP 1 Score: 459.144 bits (1180), Expect = 7.695e-142 Identity = 339/1103 (30.73%), Postives = 540/1103 (48.96%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEEL------IKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESI--LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVA--TAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDV----LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNG-FMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVN-GCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGYVIN 3330
P+L +I D D +R ++ K DVNI+D+ +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS + + VL+ AD N RD W HV A++ +V C + ++P + +N++D GRTALHHA +GH E+V++LL ++I N DK D A+H A+ MGH+++V L+E GAE+DC +G + LH A+++ ++ V L + NS HL + QD V++ E +++ +N N +G ++LH S C +LLLA+GA N S++GK+PLH AA+ + + LI+ A+V+ +D + NT LHIA R+G+E + LL++ AN G MLP+H+A + F +C C L + T D GR +H A AGG+L+CL ++ +G D + +D+ + PLH A N+ L+ GAS++ D+ C +HYA+ + +G + L N A D K+ VH+A G L LE++ +E D + +++S + +D V LS +HLAA+HGH L L+ V + G T L L+ +GH V LL GA P D ALH AA G + L ++ + +N+ +D+ D ++PLM+AV +GH L+ +GA V+ +D +GRT+LHR G +CV+ LL A + + D RGR ++A++ GH +L L+ G + +H + +Q Y TPLH+A G+ C+E+L E + +K+ G + LHCA+ S + E ++ ++N D P+ A D+V + L+ H A +N DV TP+M+AA G + + +L+ +L D LH A ++ ++ILEK+ + L+N + QTP H+AA L + + L+ GA + + P ++C N +DC+ + L +M +T A+ T LSP + VIN
Sbjct: 10 PHLLKAIFSVDPDEVRSLIFKKEDVNIQDSEKRTPLHAAAYLGDAEIIELLILSGARVNAKDNKWLTPLHRAVASCCEDAVAVLLKHSADVNARDKNWQTPLHVAASNKAVRCAEALVPQLSNVNVSDRAGRTALHHAAFSGHTEMVRLLLSRGSNI---------------------------------NAFDKKDRRAIHWAAYMGHLEVVKLLVESGAEVDCKDKKGYSPLHAAASSGMSSTVHYLLGLGVHVNEANSYGNTPLHLACYNGQD----------VVVGELIQAGANVNQVNERGFSALHFASSSRQGALCQELLLAHGACINSRSKDGKTPLHMAATHGRFSCSQALIQNGAEVDCEDKNRNTALHIAARYGHELIITALLKHGANTARRGIHAMLPLHLAALSGFSDC-CRKLLSSGFVIDT------PDEFGRTCLHAAAAGGNLECLNLLLNVGADFNRKDHFGRAPLHYASANCNYQSVFALVGSGASVNDPDQRGCTPLHYASASDTDGKCVEYLLRNDA--------------------DPRVRDKQGYTAVHYAAAYGR----TLCLELIASETPFDVL---METSGTEIL-RDSVSQLPLSPLHLAAFHGHCGALEVLLSSLLD--VDVRSPEGWTPLSLSCSRGHHECVSLLLHHGASPMIHDYMQKKTALHTAAMNGHAECLRLLLSN---DNQHMNIDTQDSSGQTPLMLAVLSGHIECVYSLLSHGASVEFQDCWGRTALHRGAVTGQEDCVEALLQRQAGVCVKDTRGRTPLHLASACGHVGVLGALLQTA------GSSLTHTH---------LTDNQGY-TPLHWACYNGYDACVELLLE-QEMVKNIKGNSFSPLHCAVMSDNEGVAEMLIDSLGASIVNATDAKGRIPLHAAAFSDHVECVSLLLSHGAQVNVGDVQMHRTPLMMAALNGQTNTVEVLVSSGKADLSLQDTERNTALHLACSKGHETSALLILEKVS-DRNLVNCTNAALQTPLHIAARRGLTVVVQELLGKGASVLAVDENGYTPALACAPNRDVADCLALILNSMMPTTPMVTIAAIPT---LSPTQP-VIN 1007 HSP 2 Score: 68.1662 bits (165), Expect = 4.820e-11 Identity = 61/184 (33.15%), Postives = 89/184 (48.37%), Query Frame = 1
Query: 52 MNTNIIPNLFNSI---LESDSDGLRCKLYNKLD---VNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVN-GVTPLFKACASNSHNVLTVLISSG-ADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLG---INITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRP 570
M NI N F+ + + SD++G+ L + L VN DA + LH AA+ + +L+ +G VN DV TPL A + N + VL+SSG AD + +D + N A H+ + LIL V +N T++ +T LH A G VV+ LL S+ A D+NG P
Sbjct: 780 MVKNIKGNSFSPLHCAVMSDNEGVAEMLIDSLGASIVNATDAKGRIPLHAAAFSDHVECVSLLLSHGAQVNVGDVQMHRTPLMMAALNGQTNTVEVLVSSGKADLSLQDTERNTALHLACSKGHETSALLILEKVSDRNLVNCTNAALQTPLHIAARRGLTVVVQELLGKGASVLAVDENGYTP 963
BLAST of Ankyrin repeat domain 28b vs. Ensembl Medaka
Match: ENSORLT00000045754.1 (serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A [Source:NCBI gene;Acc:101168382]) HSP 1 Score: 459.144 bits (1180), Expect = 7.695e-142 Identity = 339/1103 (30.73%), Postives = 540/1103 (48.96%), Query Frame = 1
Query: 70 PNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEEL------IKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESI--LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVA--TAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDV----LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNG-FMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVN-GCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGYVIN 3330
P+L +I D D +R ++ K DVNI+D+ +T LH AAY+G++ I ++LI G VN+KD +TPL +A AS + + VL+ AD N RD W HV A++ +V C + ++P + +N++D GRTALHHA +GH E+V++LL ++I N DK D A+H A+ MGH+++V L+E GAE+DC +G + LH A+++ ++ V L + NS HL + QD V++ E +++ +N N +G ++LH S C +LLLA+GA N S++GK+PLH AA+ + + LI+ A+V+ +D + NT LHIA R+G+E + LL++ AN G MLP+H+A + F +C C L + T D GR +H A AGG+L+CL ++ +G D + +D+ + PLH A N+ L+ GAS++ D+ C +HYA+ + +G + L N A D K+ VH+A G L LE++ +E D + +++S + +D V LS +HLAA+HGH L L+ V + G T L L+ +GH V LL GA P D ALH AA G + L ++ + +N+ +D+ D ++PLM+AV +GH L+ +GA V+ +D +GRT+LHR G +CV+ LL A + + D RGR ++A++ GH +L L+ G + +H + +Q Y TPLH+A G+ C+E+L E + +K+ G + LHCA+ S + E ++ ++N D P+ A D+V + L+ H A +N DV TP+M+AA G + + +L+ +L D LH A ++ ++ILEK+ + L+N + QTP H+AA L + + L+ GA + + P ++C N +DC+ + L +M +T A+ T LSP + VIN
Sbjct: 10 PHLLKAIFSVDPDEVRSLIFKKEDVNIQDSEKRTPLHAAAYLGDAEIIELLILSGARVNAKDNKWLTPLHRAVASCCEDAVAVLLKHSADVNARDKNWQTPLHVAASNKAVRCAEALVPQLSNVNVSDRAGRTALHHAAFSGHTEMVRLLLSRGSNI---------------------------------NAFDKKDRRAIHWAAYMGHLEVVKLLVESGAEVDCKDKKGYSPLHAAASSGMSSTVHYLLGLGVHVNEANSYGNTPLHLACYNGQD----------VVVGELIQAGANVNQVNERGFSALHFASSSRQGALCQELLLAHGACINSRSKDGKTPLHMAATHGRFSCSQALIQNGAEVDCEDKNRNTALHIAARYGHELIITALLKHGANTARRGIHAMLPLHLAALSGFSDC-CRKLLSSGFVIDT------PDEFGRTCLHAAAAGGNLECLNLLLNVGADFNRKDHFGRAPLHYASANCNYQSVFALVGSGASVNDPDQRGCTPLHYASASDTDGKCVEYLLRNDA--------------------DPRVRDKQGYTAVHYAAAYGR----TLCLELIASETPFDVL---METSGTEIL-RDSVSQLPLSPLHLAAFHGHCGALEVLLSSLLD--VDVRSPEGWTPLSLSCSRGHHECVSLLLHHGASPMIHDYMQKKTALHTAAMNGHAECLRLLLSN---DNQHMNIDTQDSSGQTPLMLAVLSGHIECVYSLLSHGASVEFQDCWGRTALHRGAVTGQEDCVEALLQRQAGVCVKDTRGRTPLHLASACGHVGVLGALLQTA------GSSLTHTH---------LTDNQGY-TPLHWACYNGYDACVELLLE-QEMVKNIKGNSFSPLHCAVMSDNEGVAEMLIDSLGASIVNATDAKGRIPLHAAAFSDHVECVSLLLSHGAQVNVGDVQMHRTPLMMAALNGQTNTVEVLVSSGKADLSLQDTERNTALHLACSKGHETSALLILEKVS-DRNLVNCTNAALQTPLHIAARRGLTVVVQELLGKGASVLAVDENGYTPALACAPNRDVADCLALILNSMMPTTPMVTIAAIPT---LSPTQP-VIN 1007 HSP 2 Score: 68.1662 bits (165), Expect = 4.820e-11 Identity = 61/184 (33.15%), Postives = 89/184 (48.37%), Query Frame = 1
Query: 52 MNTNIIPNLFNSI---LESDSDGLRCKLYNKLD---VNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVN-GVTPLFKACASNSHNVLTVLISSG-ADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLG---INITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRP 570
M NI N F+ + + SD++G+ L + L VN DA + LH AA+ + +L+ +G VN DV TPL A + N + VL+SSG AD + +D + N A H+ + LIL V +N T++ +T LH A G VV+ LL S+ A D+NG P
Sbjct: 780 MVKNIKGNSFSPLHCAVMSDNEGVAEMLIDSLGASIVNATDAKGRIPLHAAAFSDHVECVSLLLSHGAQVNVGDVQMHRTPLMMAALNGQTNTVEVLVSSGKADLSLQDTERNTALHLACSKGHETSALLILEKVSDRNLVNCTNAALQTPLHIAARRGLTVVVQELLGKGASVLAVDENGYTP 963
BLAST of Ankyrin repeat domain 28b vs. Planmine SMEST
Match: SMESG000074871.1 (SMESG000074871.1) HSP 1 Score: 2203.71 bits (5709), Expect = 0.000e+0 Identity = 1108/1111 (99.73%), Postives = 1110/1111 (99.91%), Query Frame = 1
Query: 52 MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGYVINLKEAELEGSIQSSENEYF 3384
MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGDLEILNLLLDNDANMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCV TQGNNALHLASANNHTNIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDIL+LLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHK+LLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGYVINLKEAELEGSIQSSENEYF
Sbjct: 1 MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGDLEILNLLLDNDANMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVATQGNNALHLASANNHTNIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILKLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKDLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGYVINLKEAELEGSIQSSENEYF 1111
BLAST of Ankyrin repeat domain 28b vs. Planmine SMEST
Match: SMESG000074871.1 (SMESG000074871.1) HSP 1 Score: 2139.77 bits (5543), Expect = 0.000e+0 Identity = 1068/1111 (96.13%), Postives = 1075/1111 (96.76%), Query Frame = 1
Query: 52 MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGYVINLKEAELEGSIQSSENEYF 3384
MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIE++ +LLDN+ + MNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCV TQGNNALHLASANNHTNIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDIL+LLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHK+LLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGYVINLKEAELEGSIQSSENEYF
Sbjct: 1 MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEILNLLLDNDAN---------------------------------MNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVATQGNNALHLASANNHTNIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILKLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKDLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEICLAAMFSSTDSPANLALKTSLNLSPKKGYVINLKEAELEGSIQSSENEYF 1078
BLAST of Ankyrin repeat domain 28b vs. Planmine SMEST
Match: SMESG000043477.1 (SMESG000043477.1) HSP 1 Score: 238.424 bits (607), Expect = 4.817e-64 Identity = 228/867 (26.30%), Postives = 394/867 (45.44%), Query Frame = 1
Query: 88 ILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEH----------LKSNSHQDLIEEIKDN------HFVLIKERLESI---------LNSRNYQGLTSLHILSQMDNAH-QCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLL--SCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHT 2604
+++ +++G+R L + I D Y +H+A G +I +L+ ++ + +G+ P+ A + +L +L+ + C D R H + + + LKL+L I+ D G +H A NG E++K+LLD+N +I DK+G RPIHWA+ G E+L LLLD + N++ DK +H AS+ GH +++ L+++ +DC G + L LA NH + VE L H L++ +++N + +++I DN H R+ + + N + +H S+ N H + + LLL N S++G P+H A+S + LL+ K + +D P+H A R G+ + +++LL+ K N + PIH A++ + + KLL N +D LG +H A + G + L+ ++ I ED L P+H A + ++ I ++L+ I+ E + IHYA+ +N +IL+LL D N + EN K + P+HFA +G+ + + LLL+ N ++C +S + IHLA+ +GHSEIL L+ K I+ +D+ G +H A+ GH+ +K LL C + + ++ +H A+S G + L ++ +RK ++ D+ + P+ A NGH+ + LI ++ +D G +H A+ +GH E + LLLDCN KIE + A+ GH +L L++ I + DI + P+H+A+ GH+
Sbjct: 204 LMKGNAEGVRNNLIEEFVDKIVDNYGYFPIHIACRNGFFSIVRLLLDRNCNIECESKSGMRPIHCASHNGHSEILKLLLDHNCNIECEDISGWRPIHWASRNGHSELLKLLLDCNCNIDCEDKSGMRPIHWASHNGQSEILKLLLDHNCNIECEDKSGWRPIHWASRNGHSELLKLLLDCNCNIDCEDKSGNRPIHYASSNGHSELLKLLLQQKCRIDCKNKDGKSPLDLAKQYNHVDCVELLAHMEKRPHFQLKNYCEYFTNMDPIRNNLRDEFVDKIVDNDGNFYIHTTCRDGRIAFVSLLLHRNGNIECENKWRMRPIHFASR--NGHSEILKLLLDRKCNIECESKSGNRPIHLASSNGHSEILKLLLDRKCTIECEDKLGMRPIHWASRNGHSEILKLLLDRKCNIECESKSRNRPIHYASSNGHSEIL-KLLINRKCIIEC----EDKLGMRPIHWASSNGYSEILKLLLDRKCIIECEDKLGMRPIHWASRNDHSAILKLLLDCNCKIECETKSRMRPIHYAS-HNGHSEILKLLLDRKCN-----------TECEN---------KWRMRPIHFASRNGHSEILKLLLDRKCN---IEC-----ESKSGNRP--------IHLASSNGHSEILKLLLD--RKCIIECEDKLGMRPIHWASRNGHSEILKLLLDRKCNIECESKSRN---RPIHLASSNGHSEILKLLL------DRKCTIECEDKLEMRPIHYASSNGHSEILKLLINRKCIIECEDKLGMRPIHWASRHGHSEILKLLLDCNCKIECGTKSRMRPIHYASRNGHSEILKLLLDRKC--------IIECEDIL------------GMRPIHWASRNGHS 995 HSP 2 Score: 224.172 bits (570), Expect = 1.736e-59 Identity = 274/1051 (26.07%), Postives = 453/1051 (43.10%), Query Frame = 1
Query: 370 AFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHL-KSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLD-DDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLL-----------------FDNGANILSPININDHLSFIENNIMDN--------TSLGKKIVY--------------------PVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLL--SCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDF-IEKSHDIFIN---ELKSMWFDQDY---------LTPLHFAASRGHTNCIEMLY------ELSDEM-------KSTNGFMTFLHCAIDSKCDETLECVLKIANNDL---------------------INTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKASDCIEI 3234
H+ + V ++L+L I G +H A NGH E++K+LLD+N +I DK+G RPIHWA+ G E+L LLLD + N++ DK + +H AS+ GH +I+ L+++ +DC G + L LA NH + V EL+ + F EHL K N+ E +++N LI+E ++ I++ NY G +HI + + V LLL N S++G P+H A+ + LL+ ++ +D P+H A R G+ + +++LL+ N + GM PIH A+ + LLD H N++ +D G +H A G + L+ ++ +I ED P+H A + + ++L++ ID +++ + A YN D + LL F N + PI N F++ I+DN T +I + P+HFA +G+ + + LLL+ N ++C +S + IHLA+ +GHSEIL L+ K + +D+ G +H A+ GH+ +K LL C + + ++ +HYA+S G + L +I NRK +++ D+ P+ A NG++ + L+ ++ +D G +H A+ N H + LLLDCN KIE + A+ GH +L L++ N + + + H N E+ + D+ P+H A+S GH+ +++L E D++ S NG L +D KC+ +EC K N + I DK PI YA + + L+ LI I +D G PI A++ G L LLL+C K KS +HYA ++ ++L++ K +I D P H A+ N L L+ + + K + P+ + ++ DC+EI
Sbjct: 43 PIHIACRNGFVSIVRLLLDRNCNIECESKSGMRPIHCASRNGHSEILKLLLDHNCNIECEDKSGWRPIHWASRNGHSELLKLLLDCNCNIDCEDKSGWRPIHWASSNGHSEILKLLLQRKCRIDCKNKDGKSPLDLAKQYNHVDCV-ELLTYMEKKQFFKEHLMKGNA-----EGVRNN---LIEEFVDKIVD--NY-GYFPIHIACR-NGFFSIVRLLLDRNCNIECESKSGMRPIHCASHNGHSEILKLLLDHNCNIECEDISGWRPIHWASRNGHSELLKLLLDCNCNIDCEDKSGMRPIHWASHNGQSEILKLLLD------HNCNIECEDKSGWRPIHWASRNGHSELLKLLLDCNCNIDCEDKSGNRPIHYASSNGHSELLKLLLQQKCRIDCKNKDGKSPLDLAKQYN-HVDCVELLAHMEKRPHFQLKNYCEYFTN----MDPIRNNLRDEFVD-KIVDNDGNFYIHTTCRDGRIAFVSLLLHRNGNIECENKWRMRPIHFASRNGHSEILKLLLDRKCN---IEC-----ESKSGNRP--------IHLASSNGHSEILKLLLD--RKCTIECEDKLGMRPIHWASRNGHSEILKLLLDRKCNIECESKSRN---RPIHYASSNGHSEILKLLI------NRKCIIECEDKLGMRPIHWASSNGYSEILKLLLDRKCIIECEDKLGMRPIHWASRNDHSAILKLLLDCNCKIECETKSRMRPIHYASHNGHSEILKLLLDRKCNTECENKWRMRPIHFASRNGHSEILKLLLDRKCNIECESKSGNRPIHLASSNGHSEILKLLLDRKCIIECEDKLGMRPIHWASRNGHSEILKLLLDRKCN--IECESKSRNRPIHLASSNGHSEILKLLLDRKCTIECEDKLEMRPIHYASSNGHSEILKLLINRKCIIECEDKLGMRPIHWASRHGHSEILKLLLDCNC-KIECGTKSRMRPIHYASRNGHSEILKLLLDR----KCIIECEDILGMRPIHWASRNGHSKLLKLLLQWKCQIDCKTKCGKSPLDEAKQFNRV-DCVEI 1033 HSP 3 Score: 152.525 bits (384), Expect = 5.309e-37 Identity = 218/991 (22.00%), Postives = 370/991 (37.34%), Query Frame = 1
Query: 445 ITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAH-QCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVL-------------LIKAKADV-----------NIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDY--YWNAL------------------------HYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEML------YELSDEM-------KSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLL------ECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRN 3207
I D+ G +H A NG + +V++LLD N +I K+G+RPIH AS GH +I+ L++ ++C G + N H +L++ + D ++ + G +H S N H + + LLL + +++GKSPL A N + L L+K A+ I D++ P+HIACR G+ V++LL+ N + GM PI HCA G + L+ ++ +I ED P+H A + + + ++L+ +ID ED+ IH+A+ +N + +IL+LL D+ NI K P+H+A +G+ + + LLL+ N +DC D S N IH A+ +GHSE+L L+Q + + +++ G++ L LA H V+ L +P K+Y Y+ + H G + A ++L +R ++ ++ + P+ A +NGH+ + L+ +++ + G +H A++NGH E + LLLD IE D G + A+ GH +L L++ N + KS + P+H+A+S GH+ +++L E D++ S+NG+ L +D KC +I DK PI +A +D+ L+ L+ N I + + PI A+ G L LLL EC+ KW + +H+A ++ ++L++ K I + P HLA+ N L L+ + ++ PI RN
Sbjct: 35 IVDAHGYFPIHIACRNGFVSIVRLLLDRNCNIECESKSGMRPIH---------------------------------CASRNGHSEILKLLLDHNCNIECEDKSGWRP--------------------------IHWASRNGHSELLKLLLD---------CNCNIDCEDKSGWRPIHWASS--NGHSEILKLLLQRKCRIDCKNKDGKSPLDLAKQYNHVDCVELLTYMEKKQFFKEHLMKGNAEGVRNNLIEEFVDKIVDNYGYFPIHIACRNGFFSIVRLLLDRNCNIECESKSGMRPI--------------------------------------HCASHNGHSEILKLLLDHNCNIECEDISGWRPIHWASRNGHSELLKLLLDCNCNIDCEDKSGMRPIHWAS-HNGQSEILKLLLDHNCNI--------------------ECEDKSGWRPIHWASRNGHSELLKLLLDCNCN---IDC----EDKSGN---------RPIHYASSNGHSELLKLLLQQKCR--IDCKNKDGKSPLDLAKQYNHVDCVELLAHMEKRPHFQLKNYCEYFTNMDPIRNNLRDEFVDKIVDNDGNFYIHTTCRDGRI-AFVSLLL-----HRNGNIECENKWRMRPIHFASRNGHSEILKLLLDRKCNIECESKSGNRPIHLASSNGHSEILKLLLDRKCTIECEDKLGMRPIHWASRNGHSEILKLLLDRKCNIECES----KSRN----------------RPIHYASSNGHSEILKLLINRKCIIECEDKLGMRPIHWASSNGYSEILKLLLDRKC--------------IIECEDKLGMRPIHWASRNDHSAILKLLLDCNCKIECETKSRMRPIHYASHNGHSEILKLLLDRKCNTECEN-KWRM------RPIHFASRNGHSEILKLLLDR----KCNIECESKSGNRPIHLASSNGHSEILKLLLDRKCIIECEDKLGMRPIHWASRN 827 HSP 4 Score: 137.887 bits (346), Expect = 1.524e-32 Identity = 175/727 (24.07%), Postives = 296/727 (40.72%), Query Frame = 1
Query: 1093 RNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTLKTHINNLD-DDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIV-----YPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGH-----------KNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGF-MTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRNSKAS 3219
RN L + L I I D H P+HIACR G+ V++LL+ N + GM PIH A+ + + LLD H N++ +D G +H A G + L+ ++ +I ED P+H A + I ++L++ ID +++ + A YN + L + + + + NN+++ KIV +P+H A +G F + LLL+ N ++C +SK + IH A+++GHSEIL L+ + +D SG +H A+ GH+ +K LL C DK +H+A+ G + L ++ + ++ D+ P+ A +NGH+ + L+ ++D +D G +H A++NGH E + LLL +I+ + G++ +A H K +L NY + D F++++ D D +H G + +L + ++ N + M +H A + E L+ +L N I K PI A + + L+ L+ I +D G PI A++ G L LLL+ + KS +HYA + IL+ L K +I D P H A+ N L L+ + ++ PI RN ++
Sbjct: 24 RNNLSEEFLDI-------IVDAHGYFPIHIACRNGFVSIVRLLLDRNCNIECESKSGMRPIHCASRNGHSEILKLLLD------HNCNIECEDKSGWRPIHWASRNGHSELLKLLLDCNCNIDCEDKSGWRPIHWASSNGHSEILKLLLQRKCRIDCKNKDGKSPLDLAKQYNHVDCVELLTYMEKKQFFKEHLMKGNAEGVRNNLIE--EFVDKIVDNYGYFPIHIACRNGFFSIVRLLLDRNCN---IEC------------ESKSG-MRPIHCASHNGHSEILKLLLDHNCN--IECEDISGWRPIHWASRNGHSELLKLLLDCNCNIDCEDKSGM-RPIHWASHNGQSEILKLLL------DHNCNIECEDKSGWRPIHWASRNGHSELLKLLLDCNCNIDCEDKSGNRPIHYASSNGHSELLKLLLQQKCRIDCKNKDGKSPLDLAKQYNHVDCVELLAHMEKRPHFQLKNYCEYFTNMDPIRNNLRDEFVDKI----VDNDGNFYIHTTCRDGRIAFVSLLLHRNGNIECENKWRMRPIHFASRNGHSEILKLLLDRKCN--IECESKSGNRPIHLASSNGHSEILKLLLDRKCTIECEDKLGMRPIHWASRNGHSEILKLLLD-RKCNIECESKSRNRPIHYASSNGHSE----ILKLLINRKCIIECEDKLGMRPIHWASSNGYSEILKLLLDRKCIIECEDKLGMRPIHWASRNDHSA 699 HSP 5 Score: 77.7962 bits (190), Expect = 4.348e-14 Identity = 59/210 (28.10%), Postives = 97/210 (46.19%), Query Frame = 1
Query: 103 SDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIV--IRLIEK 726
S+ L+ L K ++ + +HLA+ G+S I +L+ + +D + P+ A ++ +L +LI+ C D R H + H + LKL+L I +H+A NGH E++K+LLD I D G+RPIHWA+ G ++L LLL ++ + K + L A +D V + L+EK
Sbjct: 830 SEILKLLLDRKCNIECESKSRNRPIHLASSNGHSEILKLLLDRKCTIECEDKLEMRPIHYASSNGHSEILKLLINRKCIIECEDKLGMRPIHWASRHGHSEILKLLLDCNCKIECGTKSRMRPIHYASRNGHSEILKLLLDRKCIIECEDILGMRPIHWASRNGHSKLLKLLLQWKCQIDCKTKCGKSPLDEAKQFNRVDCVEILTLMEK 1039 HSP 6 Score: 72.7886 bits (177), Expect = 1.738e-12 Identity = 88/394 (22.34%), Postives = 154/394 (39.09%), Query Frame = 1
Query: 2116 SQGSVDALNEMILSVKLEN-RKSLVDS-----LDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNG-------------------FMTFLHCAIDSKCDETLECVLKIANNDLINT-----PDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYAGQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPIVSCGRN 3207
SQG++ + +++ +E R +L + +D H P+ IA +NG L+ +++ + G +H A+ NGH E + LLLD N IE D G + A+ GH LL L++ N E KS W P+H+A+S GH+ +++L + + N +T++ K + ++ + N+LI D Y + PI A + + + L+ N +I + +G PI A+ G L LLL+ D S +H+A ++ ++L+ I+ D + P H A+ N L L+ ++ ++ PI RN
Sbjct: 4 SQGALKCFKKHLINGNVEGVRNNLSEEFLDIIVDAHGYFPIHIACRNGFVSIVRLLLDRNCNIECESKSGMRPIHCASRNGHSEILKLLLDHNCNIECEDKSGWRPIHWASRNGHSELLKLLLDCNCN--------------IDCEDKSGW------RPIHWASSNGHSEILKLLLQRKCRIDCKNKDGKSPLDLAKQYNHVDCVELLTYMEKKQFFK-EHLMKGNAEGVRNNLIEEFVDKIVDNYGYFPIHIACRNGFFSIVRLLLDRNCNIECESKSGMRPIHCASHNGHSEILKLLLD-HNCNIECEDISGWRPIHWASRNGHSELLKLLLD----CNCNIDCEDKSGMRPIHWASHNGQSEILKLLLDHNCNIECEDKSGWRPIHWASRN 371
BLAST of Ankyrin repeat domain 28b vs. Planmine SMEST
Match: SMESG000017135.1 (SMESG000017135.1) HSP 1 Score: 225.328 bits (573), Expect = 1.688e-60 Identity = 220/950 (23.16%), Postives = 389/950 (40.95%), Query Frame = 1
Query: 130 NKLDVNIKDAYDQT--ALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAH-QCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTL--KTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRG-RNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTN-------------GFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLL 2922
+K D+ D D T ++H A G+ N+ L+ +V + + P+ +A ++ +LI D D + H+ H D +KL++ H I R +H A G +++VK+L+D+ I A DK PIH+A +G +I+ LL+D ++ D + +H+A GH+DIV LI++ +++ +H+A E++K L H +E K ++ + + HF ++K ++ + + I H V LL+ + + + P+HFA + L LLI K D+ D+++ P+H+AC G + V++L++ + E PIHVA C H D V L H + D + ++ A G L+ ++ +I DI DN Q P+H+A +F + ++LI I+ D I Y A DI++LL D +I S N P+H A + + + LL+ + + + + IHLA +GH EI+ L+ NI + + ++ A+H A QGH VK L+ A+ + +H+A QG +D + +I + K ++++D+ + P+ A + H A+ LI +++ D +H A + GH E V LL D IE+ + G + A + GH ++ LI + IN + + +P++FA S+GH +++L + + + ++ + G + ID KCD I DK + PI +A + + ++ LI N DI ++ PI IA ++ + + LL
Sbjct: 41 HKCDIEAVDKVDVTERSIHFACKQGHLNVVKFLLDQNCNVEATMRGKIKPIHRATRKGHIKIVELLIDHKCDIEAVDRSLVKPIHLACKHGFPDIVKLLIDHNCDIEARKGCNRRPIHFACERGRLDIVKLLIDHKCDIEAVDKRNRCPIHFACEQGHFDIVKLLIDQKCDIESADNSNQRPIHVACEQGHLDIVKLLIDQKCDIESADNYKQRPIHVACEKGKL----EIVKLLIDQHCDIEACKESNQCPIHVACEHGHFDIVKLLIDQHCDIESADNSNQRPIYVACKQGHFDIVKLLIDQKCDIESADNSNQRPIHFACEQGHLDIVKLLIDQKCDIESADNYKQRPIHVACEKGKLEIVKLLIDQHCDIEACKESNQRPIHVA-------CEHGHFDIVKLLIDQHCDIESADNSNQRPIYVACKKGHLEIVKLLINQHCDIESADNCNQRPIHVACNQGHFEVVKLLIDQHCDIESADNSNQRPI-YVACKQGHLDIVKLLIDQKCDIESADNYKQ--------------------RPIHVACEKNHLEIVKLLIGQ--------------NCDIEAFNKRKGLSHPIHLACKNGHLEIVKLLIN-KKCNIEACRYQNSERAIHFACEQGHLEIVKLLIDQHCDIEAIGGRWKNRPIHFACEQGHLDIVKLLI------DHKCDIEAMDKCNKRPIHFACEKDHLEIAKVLIEKKCNIEAWDINNLRPIHLACSYGHAEIVTLLFDAKCNIEVQENIGLLRPIHFACNNGHLEIMKLLIAQKCD---------------INAVNKC-----FRSPVYFACSKGHLEIVKLLIDQNCDTEAVDKDNSKPIHQACRQGHLNITKLLIDHKCD--------------IEAVDKCNRRPIHFACAQGHFDIVKLLIDQNCDIEARNKWEERPIDIAKRKNQVKIVQLL 903 HSP 2 Score: 189.889 bits (481), Expect = 4.903e-49 Identity = 214/885 (24.18%), Postives = 382/885 (43.16%), Query Frame = 1
Query: 481 AVANGHIEVVKILLDNNTSISASDKNGV--RPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESI---------LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTL--KTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMD----------CIKGHVD------SSQNDYQSKDDV-LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHK--RSPLMIAVQNGHTRTAEKLIMNGADVD-LKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRN-AFYMAASAGHKNLLMKLINYVA--------NKYH-----QGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYE--LSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYA 2988
A NGH+E+VK+L+ + I A DK V R IH+A +G L ++ LLD + N+ + +H A+ GHI IV LI+ +++ V +HLA + +IV+ LI + +E K + + + HF + RL+ + + + + + +H + + V LL+ + + + P+H A + L LLI K D+ D+++ P+H+AC G + V++L++ + E PIHVA C H D V L H + D + ++ A G ++ +I DI DN Q P+H A + + I ++LI I+ D Y IH A K +I++LL D +I + N P+H A G+FD + LL++ + D C KGH++ + D +S D+ IH+A GH E++ L+ + + D S + +++A QGH VK L+ + D +Y +H A + ++ + +I + +++ ++ K P+ +A +NGH + LI +++ + ++H A GH+E V LL+D + IE R +N + A GH +++ LI++ NK + D +E + + + +D + L P+H A S GH + +L++ + E++ G + +H A ++ E ++ L IA IN +K +P+++A ++ ++ LI N D D + PI A ++G L+ LL++ VDK N+ +H+A
Sbjct: 26 ACRNGHLEIVKLLVSHKCDIEAVDKVDVTERSIHFACKQGHLNVVKFLLDQNCNVEATMRGKIKPIHRATRKGHIKIVELLIDHKCDIEAVDRSLVKPIHLACKHGFPDIVKLLI----DHNCDIEARKGCNRRPI-------HFACERGRLDIVKLLIDHKCDIEAVDKRNRCPIHFACEQGHF-DIVKLLIDQKCDIESADNSNQRPIHVACEQGHLDIVKLLIDQKCDIESADNYKQRPIHVACEKGKLEIVKLLIDQHCDIEACKESNQCPIHVA-------CEHGHFDIVKLLIDQHCDIESADNSNQRPIYVACKQGHFDIVKLLIDQKCDIESADNSNQRPIHFACEQGHLDIVKLLIDQKCDIESADNYKQRPIHVACEKGK-LEIVKLLIDQHCDIEACKESNQ--------------------RPIHVACEHGHFDIVKLLIDQHCDIESADNSNQRPIYVACKKGHLEIVKLLINQHCDIESADNCNQRPIHVACNQGHFEVVKLLIDQHCD--IESADNSNQRPIYVACKQGHLDIVKLLIDQKCDIESAD-NYKQRPIHVACEKNHLEIVKLLI------GQNCDIEAFNKRKGLSHPIHLACKNGHLEIVKLLINKKCNIEACRYQNSERAIHFACEQGHLEIVKLLIDQHCDIEAIGGRWKNRPIHFACEQGHLDIVKLLIDHKCDIEAMDKCNKRPIHFACEKDHLEIAKVLIEKKCNIEAWDINNLRPIHLACSYGHAEIVTLLFDAKCNIEVQENIGLLRPIHFACNNGHLEIMK--LLIAQKCDINAVNKCFRSPVYFACSKGHLEIVKLLIDQNCDTEAVDKDNSKPIHQACRQGHLNITKLLID-HKCDIEAVDKCNRRPIHFA 858 HSP 3 Score: 100.523 bits (249), Expect = 3.983e-21 Identity = 112/445 (25.17%), Postives = 178/445 (40.00%), Query Frame = 1
Query: 1894 IHLAAYHGHSEILNYLVQ----IFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLL--SCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYA-GQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI-VSCGR 3204
I LA +GH EI+ LV I + + V +RS +H A QGH VKFLL +C + T K +H A +G + + +I + K ++++D P+ +A ++G + LI + D++ + R +H A G ++ V LL+D IE D R R + A GH +++ LI+ + IE + D P+H A +GH + +++L ID KCD I + D Y PI A + ++ LI + DI + PI +A + G + LL++ Q D SNQ ++ A Q D ++I +K I S DN+ Q P H A + LI D+ + Q PI V+C +
Sbjct: 23 IDLACRNGHLEIVKLLVSHKCDIEAVDKVDVTERS----IHFACKQGHLNVVKFLLDQNCNVEATMRGK---IKPIHRATRKGHIKIVELLI------DHKCDIEAVDRSLVKPIHLACKHGFPDIVKLLIDHNCDIEARKGCNRRPIHFACERGRLDIVKLLIDHKCDIEAVDKRNRCPIHFACEQGHFDIVKLLIDQKCD-------IESA-------------DNSNQRPIHVACEQGHLDIVKLL--------------------IDQKCD--------------IESADNYKQRPIHVACEKGKLEIVKLLIDQHCDIEACKESNQCPIHVACEHGHFDIVKLLID-QHCDIESADNSNQRPIYVACKQGHFDIVKLLIDQKCD-----IESADNSNQRPIHFACEQGHLDIVKLLIDQKCDIESADNYKQRPIHVACEK 394 HSP 4 Score: 82.4185 bits (202), Expect = 1.803e-15 Identity = 86/374 (22.99%), Postives = 159/374 (42.51%), Query Frame = 1
Query: 130 NKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNS-KDVNGVT-PLFKACASNSHNVLTVLISSGADTN-CRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRT-ALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAH-QCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKA 1236
K D+ D Y Q +H+A + I +LI D+ + G++ P+ AC + ++ +LI+ + CR RA H ++ +KL++ I + +H A GH+++VK+L+D+ I A DK RPIH+A + LEI +L++ N+ D ++ +H+A + GH +IV L + ++ G + NN E++K L + + + + H ++K ++ ++ S I H LL+ + + + + + P+HFA ++ LLI D+ ++ E P+ IA R K VQ+L + K+
Sbjct: 538 QKCDIESADNYKQRPIHVACEKNHLEIVKLLIGQNCDIEAFNKRKGLSHPIHLACKNGHLEIVKLLINKKCNIEACRYQNSERAIHFACEQGHLEIVKLLIDQHCDIEAIGGRWKNRPIHFACEQGHLDIVKLLIDHKCDIEAMDKCNKRPIHFACEKDHLEIAKVLIEKKCNIEAWDINNLRPIHLACSYGHAEIVTLLFDAKCNIEVQENIGLLRPIHFACNNGHL---EIMKLLIAQKCDINAVNKCFRSPVYFACSKGHLEIVKLLIDQNCDTEAVDKDNSKPIHQACRQGHLNITKLLIDHKCDIEAVDKCNRRPIHFACAQGHFDIVKLLIDQNCDIEARNKWEERPIDIAKRKNQVKIVQLLEKIKS 908
BLAST of Ankyrin repeat domain 28b vs. Planmine SMEST
Match: SMESG000017135.1 (SMESG000017135.1) HSP 1 Score: 225.328 bits (573), Expect = 2.077e-60 Identity = 220/950 (23.16%), Postives = 389/950 (40.95%), Query Frame = 1
Query: 130 NKLDVNIKDAYDQT--ALHLAAYIGNSNIADILIKYGIDVNSKDVNGVTPLFKACASNSHNVLTVLISSGADTNCRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRTALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAH-QCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTL--KTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMDCIKGHVDSSQNDYQSKDDVLSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRG-RNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTN-------------GFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLL 2922
+K D+ D D T ++H A G+ N+ L+ +V + + P+ +A ++ +LI D D + H+ H D +KL++ H I R +H A G +++VK+L+D+ I A DK PIH+A +G +I+ LL+D ++ D + +H+A GH+DIV LI++ +++ +H+A E++K L H +E K ++ + + HF ++K ++ + + I H V LL+ + + + P+HFA + L LLI K D+ D+++ P+H+AC G + V++L++ + E PIHVA C H D V L H + D + ++ A G L+ ++ +I DI DN Q P+H+A +F + ++LI I+ D I Y A DI++LL D +I S N P+H A + + + LL+ + + + + IHLA +GH EI+ L+ NI + + ++ A+H A QGH VK L+ A+ + +H+A QG +D + +I + K ++++D+ + P+ A + H A+ LI +++ D +H A + GH E V LL D IE+ + G + A + GH ++ LI + IN + + +P++FA S+GH +++L + + + ++ + G + ID KCD I DK + PI +A + + ++ LI N DI ++ PI IA ++ + + LL
Sbjct: 52 HKCDIEAVDKVDVTERSIHFACKQGHLNVVKFLLDQNCNVEATMRGKIKPIHRATRKGHIKIVELLIDHKCDIEAVDRSLVKPIHLACKHGFPDIVKLLIDHNCDIEARKGCNRRPIHFACERGRLDIVKLLIDHKCDIEAVDKRNRCPIHFACEQGHFDIVKLLIDQKCDIESADNSNQRPIHVACEQGHLDIVKLLIDQKCDIESADNYKQRPIHVACEKGKL----EIVKLLIDQHCDIEACKESNQCPIHVACEHGHFDIVKLLIDQHCDIESADNSNQRPIYVACKQGHFDIVKLLIDQKCDIESADNSNQRPIHFACEQGHLDIVKLLIDQKCDIESADNYKQRPIHVACEKGKLEIVKLLIDQHCDIEACKESNQRPIHVA-------CEHGHFDIVKLLIDQHCDIESADNSNQRPIYVACKKGHLEIVKLLINQHCDIESADNCNQRPIHVACNQGHFEVVKLLIDQHCDIESADNSNQRPI-YVACKQGHLDIVKLLIDQKCDIESADNYKQ--------------------RPIHVACEKNHLEIVKLLIGQ--------------NCDIEAFNKRKGLSHPIHLACKNGHLEIVKLLIN-KKCNIEACRYQNSERAIHFACEQGHLEIVKLLIDQHCDIEAIGGRWKNRPIHFACEQGHLDIVKLLI------DHKCDIEAMDKCNKRPIHFACEKDHLEIAKVLIEKKCNIEAWDINNLRPIHLACSYGHAEIVTLLFDAKCNIEVQENIGLLRPIHFACNNGHLEIMKLLIAQKCD---------------INAVNKC-----FRSPVYFACSKGHLEIVKLLIDQNCDTEAVDKDNSKPIHQACRQGHLNITKLLIDHKCD--------------IEAVDKCNRRPIHFACAQGHFDIVKLLIDQNCDIEARNKWEERPIDIAKRKNQVKIVQLL 914 HSP 2 Score: 189.889 bits (481), Expect = 6.095e-49 Identity = 214/885 (24.18%), Postives = 382/885 (43.16%), Query Frame = 1
Query: 481 AVANGHIEVVKILLDNNTSISASDKNGV--RPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESI---------LNSRNYQGLTSLHILSQMDNAHQCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKANAFVAGEDGMLPIHVATAFKNCGCMHKLLDNVTL--KTHINNLDDDGLGRNLVHCAVAGGSLKCLETIIRLGGDIHHEDNLKQTPLHLAVKLNNFMITRILIKLGASIDVEDEYTCMAIHYAAMYNKEGDILRLLFDNGANILSPININDHLSFIENNIMDNTSLGKKIVYPVHFAVMSGNFDGMILLLEMMPNEAKMD----------CIKGHVD------SSQNDYQSKDDV-LSLIHLAAYHGHSEILNYLVQIFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLLSCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHK--RSPLMIAVQNGHTRTAEKLIMNGADVD-LKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRN-AFYMAASAGHKNLLMKLINYVA--------NKYH-----QGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYE--LSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYA 2988
A NGH+E+VK+L+ + I A DK V R IH+A +G L ++ LLD + N+ + +H A+ GHI IV LI+ +++ V +HLA + +IV+ LI + +E K + + + HF + RL+ + + + + + +H + + V LL+ + + + P+H A + L LLI K D+ D+++ P+H+AC G + V++L++ + E PIHVA C H D V L H + D + ++ A G ++ +I DI DN Q P+H A + + I ++LI I+ D Y IH A K +I++LL D +I + N P+H A G+FD + LL++ + D C KGH++ + D +S D+ IH+A GH E++ L+ + + D S + +++A QGH VK L+ + D +Y +H A + ++ + +I + +++ ++ K P+ +A +NGH + LI +++ + ++H A GH+E V LL+D + IE R +N + A GH +++ LI++ NK + D +E + + + +D + L P+H A S GH + +L++ + E++ G + +H A ++ E ++ L IA IN +K +P+++A ++ ++ LI N D D + PI A ++G L+ LL++ VDK N+ +H+A
Sbjct: 37 ACRNGHLEIVKLLVSHKCDIEAVDKVDVTERSIHFACKQGHLNVVKFLLDQNCNVEATMRGKIKPIHRATRKGHIKIVELLIDHKCDIEAVDRSLVKPIHLACKHGFPDIVKLLI----DHNCDIEARKGCNRRPI-------HFACERGRLDIVKLLIDHKCDIEAVDKRNRCPIHFACEQGHF-DIVKLLIDQKCDIESADNSNQRPIHVACEQGHLDIVKLLIDQKCDIESADNYKQRPIHVACEKGKLEIVKLLIDQHCDIEACKESNQCPIHVA-------CEHGHFDIVKLLIDQHCDIESADNSNQRPIYVACKQGHFDIVKLLIDQKCDIESADNSNQRPIHFACEQGHLDIVKLLIDQKCDIESADNYKQRPIHVACEKGK-LEIVKLLIDQHCDIEACKESNQ--------------------RPIHVACEHGHFDIVKLLIDQHCDIESADNSNQRPIYVACKKGHLEIVKLLINQHCDIESADNCNQRPIHVACNQGHFEVVKLLIDQHCD--IESADNSNQRPIYVACKQGHLDIVKLLIDQKCDIESAD-NYKQRPIHVACEKNHLEIVKLLI------GQNCDIEAFNKRKGLSHPIHLACKNGHLEIVKLLINKKCNIEACRYQNSERAIHFACEQGHLEIVKLLIDQHCDIEAIGGRWKNRPIHFACEQGHLDIVKLLIDHKCDIEAMDKCNKRPIHFACEKDHLEIAKVLIEKKCNIEAWDINNLRPIHLACSYGHAEIVTLLFDAKCNIEVQENIGLLRPIHFACNNGHLEIMK--LLIAQKCDINAVNKCFRSPVYFACSKGHLEIVKLLIDQNCDTEAVDKDNSKPIHQACRQGHLNITKLLID-HKCDIEAVDKCNRRPIHFA 869 HSP 3 Score: 100.523 bits (249), Expect = 4.385e-21 Identity = 112/445 (25.17%), Postives = 178/445 (40.00%), Query Frame = 1
Query: 1894 IHLAAYHGHSEILNYLVQ----IFSKNIVSTQDRSGRTALHLAAYQGHAINVKFLL--SCGAKPTAVDKDYYWNALHYAASQGSVDALNEMILSVKLENRKSLVDSLDEHKRSPLMIAVQNGHTRTAEKLIMNGADVDLKDTYGRTSLHRATANGHVECVDLLLDCNAKIELFDFRGRNAFYMAASAGHKNLLMKLINYVANKYHQGDFIEKSHDIFINELKSMWFDQDYLTPLHFAASRGHTNCIEMLYELSDEMKSTNGFMTFLHCAIDSKCDETLECVLKIANNDLINTPDKYSWTPIFYAVHDDNVNALEKLILHNADINYQDVNGCTPIMIAAKEGTLSCLNLLLECQTLKWALVDKSNQNILHYA-GQSADDSCGIIILEKLPCLKKLINSLDNNQQTPAHLAAFNSLPLFLNALITFGADLYLKNFKSQLPI-VSCGR 3204
I LA +GH EI+ LV I + + V +RS +H A QGH VKFLL +C + T K +H A +G + + +I + K ++++D P+ +A ++G + LI + D++ + R +H A G ++ V LL+D IE D R R + A GH +++ LI+ + IE + D P+H A +GH + +++L ID KCD I + D Y PI A + ++ LI + DI + PI +A + G + LL++ Q D SNQ ++ A Q D ++I +K I S DN+ Q P H A + LI D+ + Q PI V+C +
Sbjct: 34 IDLACRNGHLEIVKLLVSHKCDIEAVDKVDVTERS----IHFACKQGHLNVVKFLLDQNCNVEATMRGK---IKPIHRATRKGHIKIVELLI------DHKCDIEAVDRSLVKPIHLACKHGFPDIVKLLIDHNCDIEARKGCNRRPIHFACERGRLDIVKLLIDHKCDIEAVDKRNRCPIHFACEQGHFDIVKLLIDQKCD-------IESA-------------DNSNQRPIHVACEQGHLDIVKLL--------------------IDQKCD--------------IESADNYKQRPIHVACEKGKLEIVKLLIDQHCDIEACKESNQCPIHVACEHGHFDIVKLLID-QHCDIESADNSNQRPIYVACKQGHFDIVKLLIDQKCD-----IESADNSNQRPIHFACEQGHLDIVKLLIDQKCDIESADNYKQRPIHVACEK 405 HSP 4 Score: 82.4185 bits (202), Expect = 1.683e-15 Identity = 86/374 (22.99%), Postives = 159/374 (42.51%), Query Frame = 1
Query: 130 NKLDVNIKDAYDQTALHLAAYIGNSNIADILIKYGIDVNS-KDVNGVT-PLFKACASNSHNVLTVLISSGADTN-CRDNKWNRAFHVCAAHNSVDCLKLILPHVLGINITDSDGRT-ALHHAVANGHIEVVKILLDNNTSISASDKNGVRPIHWAAARGXXXXXXXXXXXXXXMNIRDKDDYTALHIASAMGHIDIVIRLIEKGAELDCVTTQGXXXXXXXXXXXXXXIVEELIKALNSSHLFLEHLKSNSHQDLIEEIKDNHFVLIKERLESILNSRNYQGLTSLHILSQMDNAH-QCVDLLLAYGANPNLLSENGKSPLHFAASRNQLKQAVLLIKAKADVNIQDDHENTPLHIACRFGYEKFVQMLLEYKA 1236
K D+ D Y Q +H+A + I +LI D+ + G++ P+ AC + ++ +LI+ + CR RA H ++ +KL++ I + +H A GH+++VK+L+D+ I A DK RPIH+A + LEI +L++ N+ D ++ +H+A + GH +IV L + ++ G + NN E++K L + + + + H ++K ++ ++ S I H LL+ + + + + + P+HFA ++ LLI D+ ++ E P+ IA R K VQ+L + K+
Sbjct: 549 QKCDIESADNYKQRPIHVACEKNHLEIVKLLIGQNCDIEAFNKRKGLSHPIHLACKNGHLEIVKLLINKKCNIEACRYQNSERAIHFACEQGHLEIVKLLIDQHCDIEAIGGRWKNRPIHFACEQGHLDIVKLLIDHKCDIEAMDKCNKRPIHFACEKDHLEIAKVLIEKKCNIEAWDINNLRPIHLACSYGHAEIVTLLFDAKCNIEVQENIGLLRPIHFACNNGHL---EIMKLLIAQKCDINAVNKCFRSPVYFACSKGHLEIVKLLIDQNCDTEAVDKDNSKPIHQACRQGHLNITKLLIDHKCDIEAVDKCNRRPIHFACAQGHFDIVKLLIDQNCDIEARNKWEERPIDIAKRKNQVKIVQLLEKIKS 919 The following BLAST results are available for this feature:
BLAST of Ankyrin repeat domain 28b vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Ankyrin repeat domain 28b vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30007716 ID=SMED30007716|Name=Ankyrin repeat domain 28b|organism=Schmidtea mediterranea sexual|type=transcript|length=3814bpback to top protein sequence of SMED30007716-orf-1 >SMED30007716-orf-1 ID=SMED30007716-orf-1|Name=SMED30007716-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1112bp MNTNIIPNLFNSILESDSDGLRCKLYNKLDVNIKDAYDQTALHLAAYIGNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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