BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein

Overview


Name	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
Smed ID	SMED30007705
Length (bp)	3884

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein (SMED30007705) t-SNE clustered cells

Violin plots show distribution of expression levels for BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein (SMED30007705) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein (SMED30007705) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30007705

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
testis	SMED30007705	SMESG000035255.1	SMED30019353	smed_20140614	PMID:279364
copulatory apparatus	SMED30007705	SMESG000035255.1	SMED30019353	smed_20140614	PMID:279364

Note: Hover over icons to view figure legend

Homology

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Human
Match: KCTD10 (potassium channel tetramerization domain containing 10 [Source:HGNC Symbol;Acc:HGNC:23236])

HSP 1 Score: 234.572 bits (597), Expect = 2.218e-68
Identity = 116/244 (47.54%), Postives = 165/244 (67.62%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD 3557
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL ++R E+ ELL EAK+Y ++ LV+  +A +     + +D       + ++  S+  + LIA++ KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++    +D
Sbjct:   30 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAAL-----QNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQD 263

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Human
Match: TNFAIP1 (TNF alpha induced protein 1 [Source:HGNC Symbol;Acc:HGNC:11894])

HSP 1 Score: 223.016 bits (567), Expect = 2.046e-64
Identity = 118/254 (46.46%), Postives = 163/254 (64.17%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKR 3593
            +Y++LNVGGSL+YTT+  L    D+M  AMFSGRMEV  D EGW+LIDRCGKHF  ILN+LRD  I L  NR E+ EL+ EAK+Y ++ LV   ++ +     +++D       I I+   +  + LI S+ KPVVKL  NR NN +SYTSNS D+LL+N+E  +K +L F   + F+KDV      ++IC WSF+ +G KL  + C +I Y+TEK+  KVEF E+RI+EE L ++   T  + D  L E + R
Sbjct:   28 KYVQLNVGGSLYYTTVRAL-TRHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQ----DKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSR 272

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Human
Match: KCTD13 (potassium channel tetramerization domain containing 13 [Source:HGNC Symbol;Acc:HGNC:22234])

HSP 1 Score: 219.935 bits (559), Expect = 3.999e-63
Identity = 118/256 (46.09%), Postives = 162/256 (63.28%), Query Frame = 3

Query: 2814 SLDQSVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSE 3581
             L  + +Y+KLNVGGSL YTT+ TL    D+M  AMFSGR+EV  D+ GWVLIDR G+HF  ILN+LRDG +PL ++  EL ELL EA++Y ++ L++  +  +     ++ +  S    I +V   R  + L+AST KPVVKL  NR NN +SYTS S DNLL+N+E  +K AL F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI EE L ++   T    D  L E
Sbjct:   35 PLTPNSKYVKLNVGGSLHYTTLRTL-TGQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQ----QKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVL----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLE 281

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Query: 2814 SLDQSVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSE 3581
             L  + +Y+KLNVGGSL YTT+ TL    D+M  AMFSGR+EV  D+ GWVLIDR G+HF  ILN+LRDG +PL ++  EL ELL EA++Y ++ L++  +  +     ++ +  S    I +V   R  + L+AST KPVVKL  NR NN +SYTS S DNLL+N+E  +K AL F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI EE L ++   T    D  L E
Sbjct:   35 PLTPNSKYVKLNVGGSLHYTTLRTL-TGQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQ----QKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVL----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLE 281

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Human
Match: KCTD10 (potassium channel tetramerization domain containing 10 [Source:HGNC Symbol;Acc:HGNC:23236])

HSP 1 Score: 200.29 bits (508), Expect = 8.386e-57
Identity = 105/244 (43.03%), Postives = 149/244 (61.07%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD 3557
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL ++R E+ ELL EAK+Y ++ LV+  +A +     + +D       + ++  S+  + LIA++ KP VKL  NR NN +SYT                        + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++    +D
Sbjct:   27 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAAL-----QNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTR-----------------------VLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQD 237

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Celegans
Match: D2045.8 (pep chromosome:WBcel235:III:10482288:10483926:1 gene:WBGene00008425.1 transcript:D2045.8.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:D2045.8)

HSP 1 Score: 96.2857 bits (238), Expect = 8.847e-22
Identity = 74/225 (32.89%), Postives = 109/225 (48.44%), Query Frame = 3

Query: 2838 LKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRS-----IDCMAIHYSTEKRLIKVE 3497
            +KL+VGG +F TTI TL    DSM   MF   + V K+ EG V IDR  KHF LILNFLRDG+I L D+  E+ E+L EA ++ L+ L++          C E    S      +V     A+ +I +T KP+V L +     V+  TS +        +   + +  +   + F+     +F  N+ C WSF  R  K+ +     +DC  +    +K L   E
Sbjct:    7 VKLDVGGKIFKTTIFTL-CKHDSMLKTMFCTDVPVTKNEEGSVFIDRDSKHFRLILNFLRDGQIALPDSDREVREVLAEASYFLLDPLIEL---------CGERLEQSLNPYYHLVSTVLEARKIIFATEKPIVVLRL----PVYIATSGNQSYYFSETK-FRELSEEYHKHVAFILITEPEF--NEDCSWSFFLRAKKITARIKGPMDCNLVEECMQKLLKDAE 214

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Celegans
Match: ZC239.4 (pep chromosome:WBcel235:II:3214452:3215565:1 gene:WBGene00022567.1 transcript:ZC239.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZC239.4)

HSP 1 Score: 85.1149 bits (209), Expect = 5.317e-18
Identity = 58/198 (29.29%), Postives = 101/198 (51.01%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFE---NNQIC-EWS 3413
            E +KL+VGG++F T+  TL    D  F  M    + +  D  G + IDR  KHF+LILNF+RDG + L  N  +L+EL+ EA++Y L+ L+  + +    +  +E+ +  ++   I+  +S+  +VL  +  KP++ + +            S D+   N+   + +     +  +FV+  S +F       IC EWS
Sbjct:    3 EAVKLDVGGTIFKTSKSTLTKF-DGFFRTMLGSGIGLNVDESGCIFIDRSPKHFDLILNFMRDGCLALPKNERDLTELMAEAQYYLLDGLIDRLASSNWSVESDEKTINVAKRLPILENNSQFLQVL-CNQEKPILLIVV----------MASRDHFFPNMSIPDGF-----NAYKFVEKYSHQFHIYFKGCICLEWS 183

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Celegans
Match: ZC239.14 (pep chromosome:WBcel235:II:3221126:3222010:-1 gene:WBGene00022572.1 transcript:ZC239.14.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZC239.14)

HSP 1 Score: 82.0333 bits (201), Expect = 4.891e-17
Identity = 56/159 (35.22%), Postives = 88/159 (55.35%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLR 3308
            E +KL+VGG++F T+  TL    +  F  M    + +K D  G + IDR  KHF+LILNF+RDG++ L +   +L ELLVEA+FY L+ L++   +KI  +  E   L   +    I  ++++ ++L A   KP++         +  Y  N+ D LLR
Sbjct:    3 EIVKLDVGGTIFKTSKSTL-TKFNGFFKTMLECDIGLKLDESGCIFIDRSPKHFDLILNFMRDGDVALPNCELKLKELLVEAQFYLLDGLIEMCNSKI--MPVEPPKLVGRKFQ-FIESNAKLLQIL-ADHQKPLL---------IIGYVHNT-DILLR 146

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Celegans
Match: C17F4.8 (pep chromosome:WBcel235:II:3230817:3234813:-1 gene:WBGene00015914.1 transcript:C17F4.8.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C17F4.8)

HSP 1 Score: 80.4925 bits (197), Expect = 1.142e-16
Identity = 42/96 (43.75%), Postives = 59/96 (61.46%), Query Frame = 3

Query: 2838 LKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKI 3125
            +KLNVGG++F T+  TL    D  F  M    + ++KD    + IDR  KHF++ILNFLRDG++ L +   E++E+  EA+FY LE LV     KI
Sbjct:    8 VKLNVGGTVFQTSKSTL-TMIDGFFKMMLESDIPLQKDDSNCIFIDRSPKHFDIILNFLRDGDVDLPEQEKEINEVKREAQFYLLEELVDLCHRKI 102

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Celegans
Match: ZC239.16 (pep chromosome:WBcel235:II:3224770:3225285:-1 gene:WBGene00022574.1 transcript:ZC239.16.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZC239.16)

HSP 1 Score: 78.5666 bits (192), Expect = 1.612e-16
Identity = 41/91 (45.05%), Postives = 57/91 (62.64%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLV 3104
            E +KL+VGG++F T+  TL     S F  M   +   K +  G + IDR  KHF LILN +RDG++PL ++  EL EL+ EA+FY L+ LV
Sbjct:    3 EIIKLDVGGTIFKTSKDTLTKFH-SFFKTMLECKTGPKIEKTGCIFIDRSPKHFELILNLMRDGDLPLPEDERELRELMAEAQFYWLDGLV 92

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Fly
Match: CG10465 (gene:FBgn0033017 transcript:FBtr0086094)

HSP 1 Score: 238.039 bits (606), Expect = 3.834e-70
Identity = 119/251 (47.41%), Postives = 166/251 (66.14%), Query Frame = 3

Query: 2823 QSVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAEL 3575
             S +YLKLNVGG L+YTTIGTL   +D+M SAMFSGRMEV  DSEGW+LIDRCG HF +ILN+LRDG +PL +   E++ELL EAK+YC+  L  S E  +   H E + +      I ++   +  ++L++ +LKP V L + R NN +SYTS S DNLL+N+E  +K +L F + I F+KDV      ++IC WSF+  G K+  + C +I Y+T+++  KVEF E+RI+EE L ++    R+  D EL
Sbjct:   16 HSSQYLKLNVGGHLYYTTIGTLTKNNDTMLSAMFSGRMEVLTDSEGWILIDRCGNHFGIILNYLRDGTVPLPETNKEIAELLAEAKYYCITELAISCERAL-YAHQEPKPI----CRIPLITSQKEEQLLLSVSLKPAVILVVQRQNNKYSYTSTSDDNLLKNIELFDKLSLRFNERILFIKDV---IGPSEICCWSFYGHGKKVAEVCCTSIVYATDRKHTKVEFPEARIYEETLQVLLYENRNAPDQEL 258

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Fly
Match: CG14647 (gene:FBgn0037244 transcript:FBtr0290222)

HSP 1 Score: 71.633 bits (174), Expect = 1.139e-12
Identity = 58/182 (31.87%), Postives = 97/182 (53.30%), Query Frame = 3

Query: 2835 YLKLNVGGSLFYTTIGTL-KNASDSMFSAMF--SGRMEV-KKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEED--LTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNV-FSYTSNSHDNLLR---NVECLEKYALMFAD 3350
            ++KLNVGG ++ TTI TL     DSM + MF  +G M+  ++D +G  LIDR  ++F  I+N+LR G+  + D+   +  +L EA+F+ + +LV  +E ++G+      D  LT +     I++ S + ++           L    + N+ F Y + SH NL     N  CLE+  L +A+
Sbjct:   35 WVKLNVGGQIYATTIDTLVGREPDSMLARMFLQNGSMKPSERDEQGAYLIDRSPRYFEPIINYLRHGQF-VCDSNISVLGVLEEARFFGIFSLVTHLEERLGQQETPLGDRPLTRNDVIKAIIQTSVITELRFQGVNLSGADLRKLDFRNINFKYANMSHCNLSHTNLNYCCLERADLQYAN 215

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Fly
Match: Ktl (gene:FBgn0038839 transcript:FBtr0347575)

HSP 1 Score: 57.7658 bits (138), Expect = 1.269e-8
Identity = 35/98 (35.71%), Postives = 56/98 (57.14%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFS-GRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAK 3122
            E ++LNVGG  + TT+ TL     ++ + +F  GR  + KDS+G   +DR G  F  IL+FLRD  + L +   E   LL EA+ + L  +++ I ++
Sbjct:    3 EIIELNVGGVSYTTTLATLLQDKSTLLAELFGEGRDSLAKDSKGRYFLDRDGVLFRYILDFLRDKALHLPEGFRERQRLLREAEHFKLTAMLECIRSE 100

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Fly
Match: Ktl (gene:FBgn0038839 transcript:FBtr0083986)

HSP 1 Score: 57.7658 bits (138), Expect = 1.269e-8
Identity = 35/98 (35.71%), Postives = 56/98 (57.14%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFS-GRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAK 3122
            E ++LNVGG  + TT+ TL     ++ + +F  GR  + KDS+G   +DR G  F  IL+FLRD  + L +   E   LL EA+ + L  +++ I ++
Sbjct:    3 EIIELNVGGVSYTTTLATLLQDKSTLLAELFGEGRDSLAKDSKGRYFLDRDGVLFRYILDFLRDKALHLPEGFRERQRLLREAEHFKLTAMLECIRSE 100

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Fly
Match: CG9467 (gene:FBgn0037758 transcript:FBtr0082156)

HSP 1 Score: 58.9214 bits (141), Expect = 2.756e-8
Identity = 36/97 (37.11%), Postives = 55/97 (56.70%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRN-ELSELLVEAKFYCLENLVKSI 3113
            S + + LNVGG  F T+  TL    D+ F+A+ SGR+   +D    + IDR    F++ILN+LR  +I   D +N E+  L  EA++Y +  L K +
Sbjct:    9 SSDLVNLNVGGQRFSTSRQTLTWIPDTFFTALLSGRISSLRDEHNAIFIDRDPTLFSIILNYLRTKDI---DIKNCEIRALRHEAEYYGITPLTKRL 102

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Zebrafish
Match: kctd10 (potassium channel tetramerization domain containing 10 [Source:ZFIN;Acc:ZDB-GENE-040426-2843])

HSP 1 Score: 231.491 bits (589), Expect = 1.487e-67
Identity = 117/244 (47.95%), Postives = 163/244 (66.80%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD 3557
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL ++R E  ELL EAK+Y ++ LV   +A +     + +D       + +V  S+  + LIA+  KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++   ++D
Sbjct:   30 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGVVPLPESRRETEELLAEAKYYLVQGLVDECQAAL-----QNKDAYEPFCKVPLVTSSKEEQRLIATANKPTVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYESQD 263

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Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD 3557
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL ++R E  ELL EAK+Y ++ LV   +A +     + +D       + +V  S+  + LIA+  KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++   ++D
Sbjct:   30 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGVVPLPESRRETEELLAEAKYYLVQGLVDECQAAL-----QNKDAYEPFCKVPLVTSSKEEQRLIATANKPTVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYESQD 263

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Zebrafish
Match: tnfaip1 (tumor necrosis factor, alpha-induced protein 1 (endothelial) [Source:ZFIN;Acc:ZDB-GENE-030131-5610])

HSP 1 Score: 207.608 bits (527), Expect = 4.207e-59
Identity = 107/262 (40.84%), Postives = 167/262 (63.74%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQS 3617
            +Y++LNVGG+L+Y+T+  L    D++  +MFSG+MEV  D EGW+LIDRCGKHF  IL++LRDG + L  +R  + ELL EAK+Y ++ L+   + ++      +++   +   I ++   +  + LI + ++PVVKL  NR NN +SYTSNS DNLL+N+E  EK +L ++  + F+KDV      ++IC WSF+ +  KL  + C +I Y+TEK+  KVEF E+RI+EE L  +   T  + D  L E ++R++   + S
Sbjct:   40 KYVQLNVGGNLYYSTLQVL-TRQDTLLRSMFSGKMEVLTDKEGWILIDRCGKHFGSILSYLRDGFVNLPKSRQSIMELLAEAKYYQIQGLIDLCQKEL------QDNKEKALCVIPVITSPKEEERLIQACVRPVVKLLYNRGNNKYSYTSNSDDNLLKNIELFEKLSLSYSGRVLFIKDVI----GDEICCWSFYGQHRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNALLYETLPIPDYSLLEATRRRTNCCSHS 290

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Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQS 3617
            +Y++LNVGG+L+Y+T+  L    D++  +MFSG+MEV  D EGW+LIDRCGKHF  IL++LRDG + L  +R  + ELL EAK+Y ++ L+   + ++      +++   +   I ++   +  + LI + ++PVVKL  NR NN +SYTSNS DNLL+N+E  EK +L ++  + F+KDV      ++IC WSF+ +  KL  + C +I Y+TEK+  KVEF E+RI+EE L  +   T  + D  L E ++R++   + S
Sbjct:   40 KYVQLNVGGNLYYSTLQVL-TRQDTLLRSMFSGKMEVLTDKEGWILIDRCGKHFGSILSYLRDGFVNLPKSRQSIMELLAEAKYYQIQGLIDLCQKEL------QDNKEKALCVIPVITSPKEEERLIQACVRPVVKLLYNRGNNKYSYTSNSDDNLLKNIELFEKLSLSYSGRVLFIKDVI----GDEICCWSFYGQHRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNALLYETLPIPDYSLLEATRRRTNCCSHS 290

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Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQS 3617
            +Y++LNVGG+L+Y+T+  L    D++  +MFSG+MEV  D EGW+LIDRCGKHF  IL++LRDG + L  +R  + ELL EAK+Y ++ L+   + ++      +++   +   I ++   +  + LI + ++PVVKL  NR NN +SYTSNS DNLL+N+E  EK +L ++  + F+KDV      ++IC WSF+ +  KL  + C +I Y+TEK+  KVEF E+RI+EE L  +   T  + D  L E ++R++   + S
Sbjct:   40 KYVQLNVGGNLYYSTLQVL-TRQDTLLRSMFSGKMEVLTDKEGWILIDRCGKHFGSILSYLRDGFVNLPKSRQSIMELLAEAKYYQIQGLIDLCQKEL------QDNKEKALCVIPVITSPKEEERLIQACVRPVVKLLYNRGNNKYSYTSNSDDNLLKNIELFEKLSLSYSGRVLFIKDVI----GDEICCWSFYGQHRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNALLYETLPIPDYSLLEATRRRTNCCSHS 290

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Xenopus
Match: endoul (endonuclease, poly(U) specific like [Source:Xenbase;Acc:XB-GENE-5883501])

HSP 1 Score: 232.646 bits (592), Expect = 9.762e-68
Identity = 115/244 (47.13%), Postives = 163/244 (66.80%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD 3557
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL + R E+ ELL EAK+Y ++ L    +A +     + +D+      + ++  S+  + LIA++ KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++    +D
Sbjct:   30 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPETRREIEELLAEAKYYLVQGLADECQASL-----QNKDVYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQD 263

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Xenopus
Match: endoul (endonuclease, poly(U) specific like [Source:Xenbase;Acc:XB-GENE-5883501])

HSP 1 Score: 231.876 bits (590), Expect = 1.830e-67
Identity = 115/244 (47.13%), Postives = 163/244 (66.80%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD 3557
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL + R E+ ELL EAK+Y ++ L    +A +     + +D+      + ++  S+  + LIA++ KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++    +D
Sbjct:   36 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPETRREIEELLAEAKYYLVQGLADECQASL-----QNKDVYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQD 269

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Xenopus
Match: tnfaip1 (TNF alpha induced protein 1 [Source:NCBI gene;Acc:549563])

HSP 1 Score: 226.098 bits (575), Expect = 1.940e-65
Identity = 124/281 (44.13%), Postives = 172/281 (61.21%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQSPSITTAQMSSERDDQEAEI 3674
            +Y++LNVGG L+YTT+  L    D+M  AMFSGRMEV  D EGW+LIDRCGKHF  ILN+LRD  I L  +R+E+ EL+ EAK+Y ++ LV   +A +     ++ D   +   I I+   +  + LI S+ KPVVKL  NR NN +SYTSNS DNLL+N+E  +K +L F   + F+KDV      ++IC WSF+ +G KL  + C +I Y+TEK+  KVEF E+RI+EE L ++   T  + D  L E + R           T +Q S   DD+  E+
Sbjct:   31 KYIRLNVGGCLYYTTVQVL-TRHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGSILNYLRDDTITLPKSRHEVKELMAEAKYYLIQGLVDKCQAALQ----DKNDTYEAVCNIPIITSPKEEEKLIESSAKPVVKLLYNRSNNKYSYTSNSDDNLLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSR-----------TRSQASHSEDDEGFEL 291

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Xenopus
Match: tnfaip1 (TNF alpha induced protein 1 [Source:NCBI gene;Acc:549563])

HSP 1 Score: 207.994 bits (528), Expect = 1.183e-58
Identity = 124/316 (39.24%), Postives = 172/316 (54.43%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYT-----------------------------------SNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQSPSITTAQMSSERDDQEAEI 3674
            +Y++LNVGG L+YTT+  L    D+M  AMFSGRMEV  D EGW+LIDRCGKHF  ILN+LRD  I L  +R+E+ EL+ EAK+Y ++ LV   +A +     ++ D   +   I I+   +  + LI S+ KPVVKL  NR NN +SYT                                   SNS DNLL+N+E  +K +L F   + F+KDV      ++IC WSF+ +G KL  + C +I Y+TEK+  KVEF E+RI+EE L ++   T  + D  L E + R           T +Q S   DD+  E+
Sbjct:   31 KYIRLNVGGCLYYTTVQVLTR-HDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGSILNYLRDDTITLPKSRHEVKELMAEAKYYLIQGLVDKCQAALQ----DKNDTYEAVCNIPIITSPKEEEKLIESSAKPVVKLLYNRSNNKYSYTRYDTFNCIGLGIWVFLCTFNSMNSYFSKGINIFTSSNSDDNLLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSR-----------TRSQASHSEDDEGFEL 326

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Xenopus
Match: ereg (epiregulin [Source:Xenbase;Acc:XB-GENE-1017166])

HSP 1 Score: 77.411 bits (189), Expect = 1.300e-14
Identity = 41/98 (41.84%), Postives = 58/98 (59.18%), Query Frame = 3

Query: 2823 QSVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIE 3116
            Q  E + LNVGG  F T + TL    D+M +AMFSGR  +  D+EG   IDR G +F  ILNFLR G++P    +  L  +  EA++Y +  L+ S++
Sbjct:   50 QLPEVIPLNVGGMGFTTRLSTLLRYEDTMLAAMFSGRHYIPTDAEGRYFIDRDGTYFGDILNFLRCGDLP---PQERLKMVYKEAQYYSIGPLLDSLD 144

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Mouse
Match: Kctd10 (potassium channel tetramerisation domain containing 10 [Source:MGI Symbol;Acc:MGI:2141207])

HSP 1 Score: 232.646 bits (592), Expect = 6.795e-68
Identity = 115/244 (47.13%), Postives = 165/244 (67.62%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD 3557
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL ++R E+ ELL EAK+Y ++ L++  +A +     + +D       + ++  S+  + LIA++ KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++    +D
Sbjct:   30 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGGVPLPESRREIEELLAEAKYYLVQGLLEECQAAL-----QNKDTYEPFCKVPVITSSKEEQRLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQD 263

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Mouse
Match: Kctd10 (potassium channel tetramerisation domain containing 10 [Source:MGI Symbol;Acc:MGI:2141207])

HSP 1 Score: 232.261 bits (591), Expect = 1.063e-67
Identity = 115/244 (47.13%), Postives = 165/244 (67.62%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD 3557
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL ++R E+ ELL EAK+Y ++ L++  +A +     + +D       + ++  S+  + LIA++ KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++    +D
Sbjct:   30 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGGVPLPESRREIEELLAEAKYYLVQGLLEECQAALQ----QNKDTYEPFCKVPVITSSKEEQRLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQD 264

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Mouse
Match: Tnfaip1 (tumor necrosis factor, alpha-induced protein 1 (endothelial) [Source:MGI Symbol;Acc:MGI:104961])

HSP 1 Score: 223.402 bits (568), Expect = 1.263e-64
Identity = 118/254 (46.46%), Postives = 162/254 (63.78%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKR 3593
            +Y++LNVGGSL+YTT+  L    D+M  AMFSGRMEV  D EGW+LIDRCGKHF  ILN+LRD  I L  +R E+ EL+ EAK+Y ++ LV + +  +     +++D       I I+   R    LI S+ KPVVKL  NR NN +SYTSNS D+LL+N+E  +K +L F   + F+KDV      ++IC WSF+ +G KL  + C +I Y+TEK+  KVEF E+RI+EE L ++   T  + D  L E + R
Sbjct:   28 KYVQLNVGGSLYYTTVRAL-TRHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQSRQEIQELMAEAKYYLIQGLVSTCQTALQ----DKKDSYQPVCNIPIITSLREEDRLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSR 272

[Close]

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKR 3593
            +Y++LNVGGSL+YTT+  L    D+M  AMFSGRMEV  D EGW+LIDRCGKHF  ILN+LRD  I L  +R E+ EL+ EAK+Y ++ LV + +  +     +++D       I I+   R    LI S+ KPVVKL  NR NN +SYTSNS D+LL+N+E  +K +L F   + F+KDV      ++IC WSF+ +G KL  + C +I Y+TEK+  KVEF E+RI+EE L ++   T  + D  L E + R
Sbjct:   28 KYVQLNVGGSLYYTTVRAL-TRHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQSRQEIQELMAEAKYYLIQGLVSTCQTALQ----DKKDSYQPVCNIPIITSLREEDRLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSR 272

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Mouse
Match: Kctd13 (potassium channel tetramerisation domain containing 13 [Source:MGI Symbol;Acc:MGI:1923739])

HSP 1 Score: 217.624 bits (553), Expect = 1.633e-62
Identity = 117/242 (48.35%), Postives = 157/242 (64.88%), Query Frame = 3

Query: 2814 SLDQSVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLI 3539
             L  + +Y+KLNVGGSL YTT+ TL    D+M  AMFSGR+EV  D+ GWVLIDR G+HF  ILN+LRDG +PL ++  EL ELL EA++Y ++ L++  +     L  + E L S    I  V   R  + L+AST KPVVKL  NR NN +SYTS S DNLL+N+E  +K AL F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI EE L ++
Sbjct:   35 PLTPNSKYVKLNVGGSLHYTTLRTL-TGQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESARELGELLGEARYYLVQGLIEDCQLA---LQQKREKL-SPLCLIPTVTSPREEQQLLASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVL----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNIL 267

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. UniProt/SwissProt
Match: sp|Q9H3F6|BACD3_HUMAN (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 OS=Homo sapiens OX=9606 GN=KCTD10 PE=1 SV=1)

HSP 1 Score: 234.572 bits (597), Expect = 1.065e-67
Identity = 116/244 (47.54%), Postives = 165/244 (67.62%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD 3557
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL ++R E+ ELL EAK+Y ++ LV+  +A +     + +D       + ++  S+  + LIA++ KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++    +D
Sbjct:   30 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAAL-----QNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQD 263

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. UniProt/SwissProt
Match: sp|Q7TPL3|BACD3_RAT (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 OS=Rattus norvegicus OX=10116 GN=Kctd10 PE=1 SV=1)

HSP 1 Score: 233.032 bits (593), Expect = 3.694e-67
Identity = 115/244 (47.13%), Postives = 165/244 (67.62%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD 3557
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL ++R E+ ELL EAK+Y ++ L++  +A +     + +D       + ++  S+  + LIA++ KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++    +D
Sbjct:   30 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLLEECQAAL-----QNKDTYEPFCKVPVITSSKEEQRLIATSDKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQD 263

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. UniProt/SwissProt
Match: sp|Q922M3|BACD3_MOUSE (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 OS=Mus musculus OX=10090 GN=Kctd10 PE=1 SV=1)

HSP 1 Score: 232.646 bits (592), Expect = 4.753e-67
Identity = 115/244 (47.13%), Postives = 165/244 (67.62%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD 3557
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL ++R E+ ELL EAK+Y ++ L++  +A +     + +D       + ++  S+  + LIA++ KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++    +D
Sbjct:   30 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGGVPLPESRREIEELLAEAKYYLVQGLLEECQAAL-----QNKDTYEPFCKVPVITSSKEEQRLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQD 263

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. UniProt/SwissProt
Match: sp|Q5F3E8|BACD2_CHICK (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 OS=Gallus gallus OX=9031 GN=TNFAIP1 PE=2 SV=1)

HSP 1 Score: 229.565 bits (584), Expect = 4.759e-66
Identity = 120/254 (47.24%), Postives = 165/254 (64.96%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKR 3593
            +Y++LNVGGSL+YTT+  L    D+M  AMFSGRMEV  D EGW+LIDRCGKHF  ILN+LRD  I L  +R E+ EL+ EAK+Y ++ LV   +A +     +++DL      I I+   +  + LI S++KPVVKL  NR NN +SYTSNS DNLL+N+E  +K +L F   + F+KDV      ++IC WSF+ +G KL  + C +I Y+TEK+  KVEF E+RI+EE L ++   T  + D  L E + R
Sbjct:   32 KYVRLNVGGSLYYTTVQVL-TRHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTIALPKHRQEIKELMAEAKYYLIQGLVDMCQAALQ----DKKDLYEPVCNIPIITSPKEEERLIESSMKPVVKLLYNRSNNKYSYTSNSDDNLLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSR 276

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. UniProt/SwissProt
Match: sp|Q28DC9|BACD2_XENTR (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 OS=Xenopus tropicalis OX=8364 GN=tnfaip1 PE=2 SV=1)

HSP 1 Score: 226.098 bits (575), Expect = 1.028e-64
Identity = 124/281 (44.13%), Postives = 172/281 (61.21%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQSPSITTAQMSSERDDQEAEI 3674
            +Y++LNVGG L+YTT+  L    D+M  AMFSGRMEV  D EGW+LIDRCGKHF  ILN+LRD  I L  +R+E+ EL+ EAK+Y ++ LV   +A +     ++ D   +   I I+   +  + LI S+ KPVVKL  NR NN +SYTSNS DNLL+N+E  +K +L F   + F+KDV      ++IC WSF+ +G KL  + C +I Y+TEK+  KVEF E+RI+EE L ++   T  + D  L E + R           T +Q S   DD+  E+
Sbjct:   31 KYIRLNVGGCLYYTTVQVL-TRHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGSILNYLRDDTITLPKSRHEVKELMAEAKYYLIQGLVDKCQAALQ----DKNDTYEAVCNIPIITSPKEEEKLIESSAKPVVKLLYNRSNNKYSYTSNSDDNLLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSR-----------TRSQASHSEDDEGFEL 291

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. TrEMBL
Match: A0A5J4NJ39 (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein OS=Paragonimus westermani OX=34504 GN=DEA37_0003733 PE=4 SV=1)

HSP 1 Score: 360.533 bits (924), Expect = 5.898e-110
Identity = 174/268 (64.93%), Postives = 215/268 (80.22%), Query Frame = 3

Query: 2814 SLDQSVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQS 3617
            S+D+   Y++LNVGG+LFYTTIGTL    ++M +AMFSGRMEVK D EGWVLIDR GKHF  +LN++RDG  PL +NR EL ELL EAKF+C+E L  + E  + R+  +E+    ++ATIIIVK    AK L+AST KPVVKLTMNRYNNVFSYTSNSHDNLLRN+ECLEKYALMF DT+ FVKDV +K E N+ICEWS++ RG++L+SIDC+AIHYS+EKRLIKVEF ESRIHEEML L+SVA+R L+DAEL +I+ R++   + S
Sbjct:    6 SVDRINSYVRLNVGGTLFYTTIGTLLRG-NTMLNAMFSGRMEVKTDDEGWVLIDRSGKHFGTLLNYIRDGSAPLPENRRELDELLAEAKFFCVEGLRLACEDALSRMTVDED--AQNRATIIIVKCPNAAKSLLASTRKPVVKLTMNRYNNVFSYTSNSHDNLLRNIECLEKYALMFPDTVLFVKDVRDKSEQNEICEWSYYCRGHRLKSIDCIAIHYSSEKRLIKVEFPESRIHEEMLSLLSVASRGLTDAELRDIAMRKANCSSGS 270

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. TrEMBL
Match: G7YDB3 (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein OS=Clonorchis sinensis OX=79923 GN=CLF_105296 PE=4 SV=1)

HSP 1 Score: 356.295 bits (913), Expect = 1.368e-108
Identity = 176/308 (57.14%), Postives = 228/308 (74.03%), Query Frame = 3

Query: 2835 YLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQS--------PSITTAQMSSERDDQEAEINSLISMPINQNVSQRSTISS 3734
            Y+KLNVGG+LFYTTIGTL    ++M +AMFSGRMEVK D EGWVLIDR GKHF  ILN++RDG +PL + R E+ ELL EA+++C++ L ++ E  + R+  +E+    ++ATI+IVK    AK L++ST KPVVKLTMNRYNNVFSYTSNSHDNLLRN+ECLEKYALMF D + FVKDV +K E N+ICEWS++YRG++L+SIDC+AIHYS+EKRLIKVEF ESRIHEEML L+SV  R LSDAEL +I+ R++   + S        P      + SE+D  E +++   +  ++ +V   STI  
Sbjct:   13 YVKLNVGGTLFYTTIGTLLRG-NTMLNAMFSGRMEVKTDDEGWVLIDRSGKHFGTILNYMRDGSVPLPETRREMEELLAEARYFCVDGLRQACEDALARMVVDED--IQNRATIVIVKCPNAAKSLLSSTKKPVVKLTMNRYNNVFSYTSNSHDNLLRNIECLEKYALMFPDKVLFVKDVRDKSEQNEICEWSYYYRGHRLKSIDCIAIHYSSEKRLIKVEFPESRIHEEMLSLLSVDIRGLSDAELRDIAMRKANCGSGSATAPFVGNPVNVLPSIVSEQD--EPDLDQTSTTTVSGSVQSHSTIPP 315

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. TrEMBL
Match: A0A4S2MA79 (BTB domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002863 PE=4 SV=1)

HSP 1 Score: 355.525 bits (911), Expect = 2.358e-108
Identity = 176/313 (56.23%), Postives = 230/313 (73.48%), Query Frame = 3

Query: 2820 DQSVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQS--------PSITTAQMSSERDDQEAEINSLISMPINQNVSQRSTISS 3734
            D+   Y+KLNVGG+LFYTTIGTL    ++M +AMFSGRMEVK D EGWVLIDR GKHF  ILN++RDG +PL + R ++ ELL EA+++C++ L ++ E  + R+  +E+    ++ATI+IVK    AK L++ST KPVVKLTMNRYNNVFSYTSNSHDNLLRN+ECLEKYALMF D + FVKDV +K E N+ICEWS++YRG++L+SIDC+AIHYS+EKRLIKVEF ESRIHEEML L+SV  R LSDAEL +I+ R++   + S        P      + SE+D  E +++   +  ++ +V   STI  
Sbjct:    8 DRVNSYVKLNVGGTLFYTTIGTLLRG-NTMLNAMFSGRMEVKTDDEGWVLIDRSGKHFGTILNYMRDGSVPLPETRRDMEELLAEARYFCVDGLRQACEDALARMVVDED--IQNRATIVIVKCPNAAKSLLSSTKKPVVKLTMNRYNNVFSYTSNSHDNLLRNIECLEKYALMFPDKVLFVKDVRDKSEQNEICEWSYYYRGHRLKSIDCIAIHYSSEKRLIKVEFPESRIHEEMLSLLSVDIRGLSDAELRDIAMRKANCGSGSATAPFVGNPVNVLPSIVSEQD--EPDLDQTSTTTVSGSVQSHSTIPP 315

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. TrEMBL
Match: A0A3R7D2L6 (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 OS=Clonorchis sinensis OX=79923 GN=KCTD10 PE=4 SV=1)

HSP 1 Score: 355.14 bits (910), Expect = 3.309e-108
Identity = 175/308 (56.82%), Postives = 228/308 (74.03%), Query Frame = 3

Query: 2835 YLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQS--------PSITTAQMSSERDDQEAEINSLISMPINQNVSQRSTISS 3734
            Y+KLNVGG+LFYTTIGTL    ++M +AMFSGRMEVK D EGWVLIDR GKHF  ILN++RDG +PL + R ++ ELL EA+++C++ L ++ E  + R+  +E+    ++ATI+IVK    AK L++ST KPVVKLTMNRYNNVFSYTSNSHDNLLRN+ECLEKYALMF D + FVKDV +K E N+ICEWS++YRG++L+SIDC+AIHYS+EKRLIKVEF ESRIHEEML L+SV  R LSDAEL +I+ R++   + S        P      + SE+D  E +++   +  ++ +V   STI  
Sbjct:   13 YVKLNVGGTLFYTTIGTLLRG-NTMLNAMFSGRMEVKTDDEGWVLIDRSGKHFGTILNYMRDGSVPLPETRRDMEELLAEARYFCVDGLRQACEDALARMVVDED--IQNRATIVIVKCPNAAKSLLSSTKKPVVKLTMNRYNNVFSYTSNSHDNLLRNIECLEKYALMFPDKVLFVKDVRDKSEQNEICEWSYYYRGHRLKSIDCIAIHYSSEKRLIKVEFPESRIHEEMLSLLSVDIRGLSDAELRDIAMRKANCGSGSATAPFVGNPVNVLPSIVSEQD--EPDLDQTSTTTVSGSVQSHSTIPP 315

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. TrEMBL
Match: A0A183LJG6 (BTB domain-containing protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS3941 PE=4 SV=1)

HSP 1 Score: 354.755 bits (909), Expect = 4.470e-108
Identity = 179/286 (62.59%), Postives = 218/286 (76.22%), Query Frame = 3

Query: 2835 YLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQSPS---------ITTAQMSSERDDQE 3665
            Y+KLNVGG LFYTTIGTL     +M +AMFSGRMEVK D +GWVLIDR GKHF  ILN++RDG  PL +NR EL EL +EAK++C++ L  + E  +GRL    EDL  ++ATIIIVK    AK L+++T KPVVKLTMNRYNNVFSYTSNSHDNLLRN+ECLEKYALMF  T+ FVKDV +K E N+ICEWS++ RG++L+SIDC+AIHYS+EKRLIKVEF ESRIHEEML L+SVA+R+LSDAEL EI+ R++   + S S          TT     E +DQ+
Sbjct:   14 YVKLNVGGCLFYTTIGTLLRGG-TMLTAMFSGRMEVKTDDDGWVLIDRSGKHFGTILNYIRDGSAPLPENRKELEELAMEAKYFCVKGLCLACEEALGRL-TNYEDL-QNRATIIIVKCPNAAKSLLSTTRKPVVKLTMNRYNNVFSYTSNSHDNLLRNIECLEKYALMFPATVLFVKDVRDKSEQNEICEWSYYCRGHRLKSIDCIAIHYSSEKRLIKVEFPESRIHEEMLSLLSVASRNLSDAELLEIAMRKANCVSGSASGALVSYSVPGTTGNSQHETEDQD 296

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Cavefish
Match: kctd10 (potassium channel tetramerization domain containing 10 [Source:NCBI gene;Acc:111196221])

HSP 1 Score: 231.876 bits (590), Expect = 9.080e-68
Identity = 122/265 (46.04%), Postives = 170/265 (64.15%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD--LSDAELSEISKRQSGTHNQ 3614
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL ++R E  ELL EAK+Y ++ LV   +A +     + +D       + +V  S+  + LIA + KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++   ++D    D  L E +   +G  N 
Sbjct:   30 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGVVPLPESRRETEELLAEAKYYLVQGLVDECQAAL-----QNKDAYEPFCKVPLVTSSKEEQRLIAKSNKPTVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYESQDGRGPDNALLEATGGAAGRSNH 284

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Cavefish
Match: tnfaip1 (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 [Source:NCBI gene;Acc:103025059])

HSP 1 Score: 207.223 bits (526), Expect = 4.897e-59
Identity = 109/262 (41.60%), Postives = 162/262 (61.83%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQS--GTHN 3611
            +Y++LNVGG L Y+T+  L    D +  +MFSG+ EV  D EGW+LIDRCGKHF  IL +LRDG + L  +R  + ELL EAK+Y ++ L+   +  +      +++   +   I ++  S+  + LI    +PVVKL  NR NN +SYTSNS DNLL+N+E  EK +L +   + F+KDV      ++IC WSF+ +G KL  + C +I Y+TEK+  KVEF E+RI+EE L  +   T  + D  L E ++R++  G+H+
Sbjct:   40 KYVRLNVGGVLHYSTVQVL-TRQDGLLKSMFSGKTEVFTDKEGWILIDRCGKHFGSILGYLRDGSLTLPKSRQGIMELLAEAKYYHIQGLIDLCQQAV------QDNKQQALCVIPVITSSKEEERLIQGCTRPVVKLLYNRSNNKYSYTSNSDDNLLKNIELFEKLSLSYNGRVLFMKDVI----GDEICCWSFYGQGRKLSEVCCTSIVYATEKKQTKVEFPEARIYEETLNALLYETLPVPDNSLLEATRRRAHCGSHS 290

[Close]

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQS--GTHN 3611
            +Y++LNVGG L Y+T+  L    D +  +MFSG+ EV  D EGW+LIDRCGKHF  IL +LRDG + L  +R  + ELL EAK+Y ++ L+   +  +      +++   +   I ++  S+  + LI    +PVVKL  NR NN +SYTSNS DNLL+N+E  EK +L +   + F+KDV      ++IC WSF+ +G KL  + C +I Y+TEK+  KVEF E+RI+EE L  +   T  + D  L E ++R++  G+H+
Sbjct:   40 KYVRLNVGGVLHYSTVQVL-TRQDGLLKSMFSGKTEVFTDKEGWILIDRCGKHFGSILGYLRDGSLTLPKSRQGIMELLAEAKYYHIQGLIDLCQQAV------QDNKQQALCVIPVITSSKEEERLIQGCTRPVVKLLYNRSNNKYSYTSNSDDNLLKNIELFEKLSLSYNGRVLFMKDVI----GDEICCWSFYGQGRKLSEVCCTSIVYATEKKQTKVEFPEARIYEETLNALLYETLPVPDNSLLEATRRRAHCGSHS 290

[Close]

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQS--GTHN 3611
            +Y++LNVGG L Y+T+  L    D +  +MFSG+ EV  D EGW+LIDRCGKHF  IL +LRDG + L  +R  + ELL EAK+Y ++ L+   +  +      +++   +   I ++  S+  + LI    +PVVKL  NR NN +SYTSNS DNLL+N+E  EK +L +   + F+KDV      ++IC WSF+ +G KL  + C +I Y+TEK+  KVEF E+RI+EE L  +   T  + D  L E ++R++  G+H+
Sbjct:   40 KYVRLNVGGVLHYSTVQVL-TRQDGLLKSMFSGKTEVFTDKEGWILIDRCGKHFGSILGYLRDGSLTLPKSRQGIMELLAEAKYYHIQGLIDLCQQAV------QDNKQQALCVIPVITSSKEEERLIQGCTRPVVKLLYNRSNNKYSYTSNSDDNLLKNIELFEKLSLSYNGRVLFMKDVI----GDEICCWSFYGQGRKLSEVCCTSIVYATEKKQTKVEFPEARIYEETLNALLYETLPVPDNSLLEATRRRAHCGSHS 290

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Cavefish
Match: kctd13 (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 [Source:NCBI gene;Acc:103030809])

HSP 1 Score: 207.223 bits (526), Expect = 5.140e-59
Identity = 107/241 (44.40%), Postives = 153/241 (63.49%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHC-----EEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLI 3539
            +Y+KLNVGGSL YTT+ TL +  DS+  +M  G  EV  DSEGWV++DRCG+HF L+LNFLRDG +PL +++ EL E+L EA++Y L+ L++         HC     +  +       I ++  ++  + +I +  KPVVKL  NR NN +SYTSNS DNLL+N+E  +K  L F   + F+KDV      ++IC WSF+  G K+  + C +I Y+TEK+  KVEF E+RI EE L ++
Sbjct:   37 KYVKLNVGGSLHYTTVQTL-SKEDSLLRSMCDGSTEVSIDSEGWVVLDRCGRHFPLVLNFLRDGTVPLPESQKELEEVLKEAQYYRLQGLIQ---------HCLSTLQKRNETYEGGCRIPMITSAKEEQRMITTCRKPVVKLQNNRGNNKYSYTSNSDDNLLKNIELFDKLGLRFNGRVLFIKDVL----GDEICCWSFYGEGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNIL 263

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Sea Lamprey
Match: kctd10 (potassium channel tetramerization domain containing 10 [Source:ZFIN;Acc:ZDB-GENE-040426-2843])

HSP 1 Score: 181.03 bits (458), Expect = 1.304e-51
Identity = 93/224 (41.52%), Postives = 137/224 (61.16%), Query Frame = 3

Query: 2958 GWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD---LSDAELSEISKRQSGTHNQSP 3620
            GW+LIDRCGKHF +ILNFLRDG +PL ++R E+ ELL EAK+Y ++ L +   A +     ++ D       + ++   +  + LI ++ KPVVKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++    RD     D  L E +   +G  +  P
Sbjct:    3 GWILIDRCGKHFGMILNFLRDGAVPLPESRTEIEELLTEAKYYLVQGLGQQCHAALQ----QKRDAVDPICRVPVITSLKEEQKLITTSNKPVVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEPRDGLGGPDKALLEATGGAAGRSHGPP 218

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Sea Lamprey
Match: kctd6a (potassium channel tetramerization domain containing 6a [Source:ZFIN;Acc:ZDB-GENE-050208-474])

HSP 1 Score: 80.4925 bits (197), Expect = 6.274e-17
Identity = 41/94 (43.62%), Postives = 56/94 (59.57%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSI 3113
            E + LNVGG L+ T+  TL   SDSM  AMFSG +   +D++G   IDR G  F  +LNFLR  E+ L  +  E+  L  EA FY +E L++ +
Sbjct:   12 EPVTLNVGGHLYSTSRATLTRYSDSMLGAMFSGDLPTARDAQGHYFIDRDGPLFRYVLNFLRTSELTLPQDFKEIDLLRKEADFYQIEQLIQCL 105

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Sea Lamprey
Match: kctd7 (potassium channel tetramerization domain containing 7 [Source:NCBI gene;Acc:735248])

HSP 1 Score: 74.3294 bits (181), Expect = 8.173e-15
Identity = 38/95 (40.00%), Postives = 56/95 (58.95%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIE 3116
            E ++LNVGG+ F T + TL++   SM +AMFSGR  + +D  G   IDR   +F  ILNFLR GE+P  +    +     EA ++ L+ L+  +E
Sbjct:    3 EVVQLNVGGTHFATLLSTLRSCEGSMLAAMFSGRHRLPRDHVGRFFIDRDPAYFGDILNFLRSGEVPCHERARGVHR---EAHYFGLQPLLACLE 94

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Sea Lamprey
Match: KCTD9 (potassium channel tetramerization domain containing 9 [Source:HGNC Symbol;Acc:HGNC:22401])

HSP 1 Score: 60.077 bits (144), Expect = 4.969e-10
Identity = 37/99 (37.37%), Postives = 56/99 (56.57%), Query Frame = 3

Query: 2829 VEYLKLNVGGSLFYTTIGTLKNA-SDSMFSAMFSGR--MEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIE 3116
             ++L LNVGG  F TT GTL N   + M + MF  R      +D  G  LIDR  ++F  ++NFLR G + + +  N L  +L EA+F+ +  L++ +E
Sbjct:   92 ADWLTLNVGGRHFTTTRGTLVNKDPNCMLAKMFDRREGWSNTRDPSGAYLIDRSPEYFEPVINFLRHGTVIVNEGLN-LQGVLEEARFFGISPLIEQME 189

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Sea Lamprey
Match: KCTD18 (potassium channel tetramerization domain containing 18 [Source:HGNC Symbol;Acc:HGNC:26446])

HSP 1 Score: 51.9878 bits (123), Expect = 3.347e-8
Identity = 26/61 (42.62%), Postives = 37/61 (60.66%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFL 3014
            + L+LNVGG        +L    DSM  AMFSGR  +K+DS G  +I+R G+ F  +L++L
Sbjct:   13 DILRLNVGGVAMTARRDSLCRYKDSMLGAMFSGRFPLKQDSTGACVIERDGQLFKYLLDYL 73

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Nematostella
Match: EDO37751 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SER8])

HSP 1 Score: 194.512 bits (493), Expect = 1.138e-55
Identity = 114/262 (43.51%), Postives = 150/262 (57.25%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATR---DLSDAELSEISKRQSG 3602
              +Y+KLNVGGSL YTT+GTL    D+M  AMFSGRMEV  DS+GW+LIDRCGKHF  ILNFLRDG IPL    +EL EL  E+K+Y +E LV   EA + +   ++ D       I   K+ R    L+ ST                S    S DNLL+N+E  +K +L F   I F+KD+     NN+IC W+++  G K+  + C +I Y+TEK+  KVEF E+RI+EE L  +    R    L DAEL   ++   G
Sbjct:   15 PTKYVKLNVGGSLHYTTLGTL-TKHDNMLRAMFSGRMEVLTDSDGWILIDRCGKHFGTILNFLRDGSIPLPQCESELRELCTESKYYLIEQLVNQCEALLAKKQ-QQHDPICRVPLITSTKEER----LLVSTA---------------SKGRQSDDNLLKNIELFDKLSLRFNGRILFIKDL---IGNNEICCWTYYGNGKKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNALLYENRMDAKLPDAELLHATRGAVG 252

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Nematostella
Match: EDO34594 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNY3])

HSP 1 Score: 83.1889 bits (204), Expect = 3.369e-19
Identity = 42/93 (45.16%), Postives = 60/93 (64.52%), Query Frame = 3

Query: 2838 LKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIE 3116
            + LNVGG ++ T+  TL    DSM  AMFSGR  + +D+ G   IDR G  F  ILNFLR  E+ L D+ +E  +L +EA FY +E+L+K+++
Sbjct:    2 VNLNVGGYVYTTSYKTLTRCRDSMLGAMFSGRQNLARDTRGNFFIDRDGSLFRYILNFLRTSELCLPDSFDEFQQLSLEADFYQIEDLIKALQ 94

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Nematostella
Match: EDO49543 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGK4])

HSP 1 Score: 75.485 bits (184), Expect = 2.679e-16
Identity = 44/98 (44.90%), Postives = 61/98 (62.24%), Query Frame = 3

Query: 2838 LKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNE--LSELLVEAKFYCLENLVKSIEAKI 3125
            +KL+VGG  F T++ TL+    SM +AMFSGR ++K+ S+    +DR G HF  ILN+LRDG +      +E  L E+  EA FY L  L+ SIEA +
Sbjct:   10 VKLDVGGHHFTTSLLTLRKEPHSMLAAMFSGRFKLKQASDESYFLDRDGTHFRHILNYLRDGFLAETFPTDEVILKEIQQEANFYQLTGLIDSIEAML 107

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Nematostella
Match: EDO34699 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNM1])

HSP 1 Score: 76.2554 bits (186), Expect = 2.680e-15
Identity = 38/93 (40.86%), Postives = 63/93 (67.74%), Query Frame = 3

Query: 2838 LKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIE 3116
            ++LNVGG L+ T++ TL   S+S+ S+MFSGR ++ +DS G   IDR G  F  IL++LR+ ++ L +  NE   L +EA+ + L+ +V++I+
Sbjct:   17 VELNVGGQLYTTSLPTLLKDSESLLSSMFSGRQKIPRDSRGRFFIDRDGVLFRYILDYLRNCKLALPEGFNERERLTMEAEHFKLKGMVRAIQ 109

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BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Nematostella
Match: EDO32194 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVR4])

HSP 1 Score: 71.633 bits (174), Expect = 5.949e-15
Identity = 46/103 (44.66%), Postives = 62/103 (60.19%), Query Frame = 3

Query: 2817 LDQSVEY---LKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIE 3116
            +D +V++   + LNVGG+ F TT+ TL    DSM  +MFSGR+ V +DS G   IDR G  F  ILNFLR   + L  N  +   LL EA FY +E L++ I+
Sbjct:    1 MDATVDFPAIIDLNVGGNHFTTTLLTLTTFPDSMLGSMFSGRIPVNRDSNGRFFIDRDGTLFRYILNFLRSNVLSLPANFKDYELLLNEADFYQIEPLIEEIK 103

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Medaka
Match: kctd10 (potassium channel tetramerization domain containing 10 [Source:NCBI gene;Acc:101170848])

HSP 1 Score: 228.409 bits (581), Expect = 1.678e-66
Identity = 120/265 (45.28%), Postives = 168/265 (63.40%), Query Frame = 3

Query: 2826 SVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRD--LSDAELSEISKRQSGTHNQ 3614
            S +Y+KLNVGG+L+YTT+ TL    D+M  AMFSGRMEV  DSEGW+LIDRCGKHF  ILN+LRDG +PL D+R E  ELL EAK+Y ++ L     A +     + ++       + ++  S+  + LIA++ KP VKL  NR NN +SYTSNS DN+L+N+E  +K +L F   + F+KDV      ++IC WSF+ +G K+  + C +I Y+TEK+  KVEF E+RI+EE L ++   + D    D  L E +   +G  N 
Sbjct:   30 SSKYVKLNVGGALYYTTMQTL-TKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPDSRRETEELLAEAKYYLVQGLSDECTAAL-----QNKETYEPLCKVPLMTSSKEEQRLIATSNKPTVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVI----GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYESHDGRGPDNALLEATGGAAGRSNH 284

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Medaka
Match: kctd13 (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 [Source:NCBI gene;Acc:101174920])

HSP 1 Score: 209.534 bits (532), Expect = 9.586e-60
Identity = 115/264 (43.56%), Postives = 162/264 (61.36%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHC-----EEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEML-MLISVATRDLSDAELSEISKRQSGT 3605
            +Y+KLNVGG+L YTT+ TL +  DS+   + +G  E   D EGWV++DRCG+HF ++LNFLRDG +PL D   EL E+L EA++Y ++ LV+         HC     +++D+  S   I ++  ++  + +IAS  KPVVKL  NR NN +SYTSNS DNLL+N+E  +K  L F   + FVKDV      ++IC WSF+  G K+  + C +I Y+TEK+  KVEF E+RI EE L +LI    R      L  +  R SG+
Sbjct:   39 KYVKLNVGGTLHYTTVQTL-SKEDSLLRRICNGETEATIDPEGWVVLDRCGRHFGVVLNFLRDGSVPLPDECRELDEVLKEAQYYQIQGLVQ---------HCISAMQKKKDILESVCGIPMITSAKEEQRMIASCKKPVVKLQNNRGNNKYSYTSNSDDNLLKNIELFDKLVLRFNGRVLFVKDVL----GDEICCWSFYGEGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYENNRRSGPGGLHLLDSRGSGS 288

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Medaka
Match: kctd13 (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 [Source:NCBI gene;Acc:101174920])

HSP 1 Score: 192.2 bits (487), Expect = 4.353e-54
Identity = 109/259 (42.08%), Postives = 148/259 (57.14%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEML-MLISVATRDLSDAELSEISKRQSGT 3605
            +Y+KLNVGG+L YTT+ TL +  DS+   + +G  E   D EGWV++DRCG+HF ++LNFLRDG +PL D   EL E+L EA++Y ++ LV+         HC                          S ++PVVKL  NR NN +SYTSNS DNLL+N+E  +K  L F   + FVKDV      ++IC WSF+  G K+  + C +I Y+TEK+  KVEF E+RI EE L +LI    R      L  +  R SG+
Sbjct:   39 KYVKLNVGGTLHYTTVQTL-SKEDSLLRRICNGETEATIDPEGWVVLDRCGRHFGVVLNFLRDGSVPLPDECRELDEVLKEAQYYQIQGLVQ---------HC-------------------------ISAMQPVVKLQNNRGNNKYSYTSNSDDNLLKNIELFDKLVLRFNGRVLFVKDVL----GDEICCWSFYGEGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYENNRRSGPGGLHLLDSRGSGS 258

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Medaka
Match: kctd13 (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 [Source:NCBI gene;Acc:101174920])

HSP 1 Score: 186.808 bits (473), Expect = 6.696e-52
Identity = 108/264 (40.91%), Postives = 154/264 (58.33%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHC-----EEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEML-MLISVATRDLSDAELSEISKRQSGT 3605
            +Y+KLNVGG+L YTT+ TL +  DS+   + +G  E   D EGWV++DRCG+HF ++LNFLRDG +PL D   EL E+L EA++Y ++ LV+         HC     +++D+  S   I ++  ++  + +IAS  KPVVKL  NR NN +SYTSNS DNLL+N+E  +K  L F   + FVKDV      ++IC WSF+  G K+             + ++ VEF E+RI EE L +LI    R      L  +  R SG+
Sbjct:   39 KYVKLNVGGTLHYTTVQTL-SKEDSLLRRICNGETEATIDPEGWVVLDRCGRHFGVVLNFLRDGSVPLPDECRELDEVLKEAQYYQIQGLVQ---------HCISAMQKKKDILESVCGIPMITSAKEEQRMIASCKKPVVKLQNNRGNNKYSYTSNSDDNLLKNIELFDKLVLRFNGRVLFVKDVL----GDEICCWSFYGEGRKIAETKVNI------ENMLAVEFPEARIFEETLNILIYENNRRSGPGGLHLLDSRGSGS 282

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Medaka
Match: kctd7 (potassium channel tetramerization domain containing 7 [Source:NCBI gene;Acc:101168068])

HSP 1 Score: 87.4261 bits (215), Expect = 8.600e-18
Identity = 42/95 (44.21%), Postives = 61/95 (64.21%), Query Frame = 3

Query: 2832 EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIE 3116
            E + LNVGG  F T + TL+   D+M +AMFSGR  + +D+EG   IDR G +F  ILNFLR+GE+PL   R+ +  +  EA++Y +  L+  +E
Sbjct:  107 EVISLNVGGMYFTTRLSTLRRYEDTMLAAMFSGRHYIPRDAEGRFFIDRDGVYFGDILNFLREGELPL---RDRVRAVYREAQYYSIGPLLDQLE 198

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Planmine SMEST
Match: SMESG000037805.1 (SMESG000037805.1)

HSP 1 Score: 652.899 bits (1683), Expect = 0.000e+0
Identity = 316/321 (98.44%), Postives = 319/321 (99.38%), Query Frame = 3

Query: 2778 FRLINFKYLMSTSLDQSVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQSPSITTAQMSSERDDQEAEINSLISMPINQNVSQRSTISSRL 3740
            F+LINF+YLMST+ DQS EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQSPSITTAQMSSERDDQEAEINSLISMPINQNVSQRSTISSRL
Sbjct:    9 FKLINFEYLMSTNFDQSGEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQSPSITTAQMSSERDDQEAEINSLISMPINQNVSQRSTISSRL 329

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Planmine SMEST
Match: SMESG000037805.1 (SMESG000037805.1)

HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0
Identity = 309/312 (99.04%), Postives = 310/312 (99.36%), Query Frame = 3

Query: 2805 MSTSLDQSVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQSPSITTAQMSSERDDQEAEINSLISMPINQNVSQRSTISSRL 3740
            MST+ DQS EYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQSPSITTAQMSSERDDQEAEINSLISMPINQNVSQRSTISSRL
Sbjct:    1 MSTNFDQSGEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMNRYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQICEWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATRDLSDAELSEISKRQSGTHNQSPSITTAQMSSERDDQEAEINSLISMPINQNVSQRSTISSRL 312

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Planmine SMEST
Match: SMESG000070841.1 (SMESG000070841.1)

HSP 1 Score: 216.468 bits (550), Expect = 1.917e-64
Identity = 108/130 (83.08%), Postives = 118/130 (90.77%), Query Frame = 3

Query: 2805 MSTSLDQSVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIEAKIGRLHCEEEDLTSSQATIIIVKDS 3194
            MST+L+QS EYLKLNVG  LFYTTIGTL+N SDSMFS    GRM++KKD+EGWVLIDRC  HFNLILNFLRDGEIPLFDN NELS+LLVEAKFYCLENLVKSIEAKIGRLH EEEDLT++QATIIIVKD+
Sbjct:    1 MSTNLNQSGEYLKLNVGDFLFYTTIGTLENESDSMFS----GRMKLKKDTEGWVLIDRCRNHFNLILNFLRDGEIPLFDNSNELSKLLVEAKFYCLENLVKSIEAKIGRLHWEEEDLTNTQATIIIVKDN 126

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Planmine SMEST
Match: SMESG000042930.1 (SMESG000042930.1)

HSP 1 Score: 62.3882 bits (150), Expect = 3.344e-11
Identity = 35/107 (32.71%), Postives = 60/107 (56.07%), Query Frame = 3

Query: 2838 LKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLV-EAKFYCLENLVKSI----EAKIGRLHCE 3143
            + LNVGG  + T + TL    DSM + MFSGR  + +D+ G   +D  G +F+ +L++LR+  +P      E++  +  EA +Y + NL +++    E KI  L+ +
Sbjct:   22 INLNVGGHFYTTRLSTLCRYPDSMLATMFSGRHTIDQDASGNYFLDNNGIYFSYLLDYLRNETLP----PKEMAVFVYKEAGYYGISNLQEALSNSPEIKITELYVQ 124

[Close]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Planmine SMEST
Match: SMESG000017037.1 (SMESG000017037.1)

HSP 1 Score: 63.5438 bits (153), Expect = 1.226e-10
Identity = 34/93 (36.56%), Postives = 55/93 (59.14%), Query Frame = 3

Query: 2844 LNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKK--DSEGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLVKSIE 3116
            +NVGG +  TT+ TL    +SM + MF G +   +  DS G + +DR G  F  +LNFLR G + L D  +  + L +EA +Y L+ L+++++
Sbjct:   20 INVGGIIHTTTLSTLCRYPNSMIARMFIGSIPPSQSIDSNGNIFLDRDGVLFGYVLNFLRSGVLTLPDGFHSFNSLQIEADYYGLDELLEALK 112

The following BLAST results are available for this feature:

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Human
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Celegans
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Fly
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Zebrafish
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Xenopus
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Mouse
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. UniProt/SwissProt
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. TrEMBL
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Cavefish
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Sea Lamprey
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Yeast
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Nematostella
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Medaka
BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Planmine SMEST

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCTD10	2.218e-68	47.54	potassium channel tetramerization domain containin...	[more]
TNFAIP1	2.046e-64	46.46	TNF alpha induced protein 1 [Source:HGNC Symbol;Ac...	[more]
KCTD13	3.999e-63	46.09	potassium channel tetramerization domain containin...	[more]
KCTD13	3.999e-63	46.09	potassium channel tetramerization domain containin...	[more]
KCTD10	8.386e-57	43.03	potassium channel tetramerization domain containin...	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
D2045.8	8.847e-22	32.89	pep chromosome:WBcel235:III:10482288:10483926:1 ge...	[more]
ZC239.4	5.317e-18	29.29	pep chromosome:WBcel235:II:3214452:3215565:1 gene:...	[more]
ZC239.14	4.891e-17	35.22	pep chromosome:WBcel235:II:3221126:3222010:-1 gene...	[more]
C17F4.8	1.142e-16	43.75	pep chromosome:WBcel235:II:3230817:3234813:-1 gene...	[more]
ZC239.16	1.612e-16	45.05	pep chromosome:WBcel235:II:3224770:3225285:-1 gene...	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG10465	3.834e-70	47.41	gene:FBgn0033017 transcript:FBtr0086094	[more]
CG14647	1.139e-12	31.87	gene:FBgn0037244 transcript:FBtr0290222	[more]
Ktl	1.269e-8	35.71	gene:FBgn0038839 transcript:FBtr0347575	[more]
Ktl	1.269e-8	35.71	gene:FBgn0038839 transcript:FBtr0083986	[more]
CG9467	2.756e-8	37.11	gene:FBgn0037758 transcript:FBtr0082156	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kctd10	1.487e-67	47.95	potassium channel tetramerization domain containin...	[more]
kctd10	1.487e-67	47.95	potassium channel tetramerization domain containin...	[more]
tnfaip1	4.207e-59	40.84	tumor necrosis factor, alpha-induced protein 1 (en...	[more]
tnfaip1	4.207e-59	40.84	tumor necrosis factor, alpha-induced protein 1 (en...	[more]
tnfaip1	4.207e-59	40.84	tumor necrosis factor, alpha-induced protein 1 (en...	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
endoul	9.762e-68	47.13	endonuclease, poly(U) specific like [Source:Xenbas...	[more]
endoul	1.830e-67	47.13	endonuclease, poly(U) specific like [Source:Xenbas...	[more]
tnfaip1	1.940e-65	44.13	TNF alpha induced protein 1 [Source:NCBI gene;Acc:...	[more]
tnfaip1	1.183e-58	39.24	TNF alpha induced protein 1 [Source:NCBI gene;Acc:...	[more]
ereg	1.300e-14	41.84	epiregulin [Source:Xenbase;Acc:XB-GENE-1017166]	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Kctd10	6.795e-68	47.13	potassium channel tetramerisation domain containin...	[more]
Kctd10	1.063e-67	47.13	potassium channel tetramerisation domain containin...	[more]
Tnfaip1	1.263e-64	46.46	tumor necrosis factor, alpha-induced protein 1 (en...	[more]
Tnfaip1	1.263e-64	46.46	tumor necrosis factor, alpha-induced protein 1 (en...	[more]
Kctd13	1.633e-62	48.35	potassium channel tetramerisation domain containin...	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9H3F6\|BACD3_HUMAN	1.065e-67	47.54	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
sp\|Q7TPL3\|BACD3_RAT	3.694e-67	47.13	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
sp\|Q922M3\|BACD3_MOUSE	4.753e-67	47.13	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
sp\|Q5F3E8\|BACD2_CHICK	4.759e-66	47.24	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
sp\|Q28DC9\|BACD2_XENTR	1.028e-64	44.13	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5J4NJ39	5.898e-110	64.93	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
G7YDB3	1.368e-108	57.14	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
A0A4S2MA79	2.358e-108	56.23	BTB domain-containing protein OS=Opisthorchis feli...	[more]
A0A3R7D2L6	3.309e-108	56.82	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
A0A183LJG6	4.470e-108	62.59	BTB domain-containing protein OS=Schistosoma margr...	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kctd10	9.080e-68	46.04	potassium channel tetramerization domain containin...	[more]
tnfaip1	4.897e-59	41.60	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
tnfaip1	4.897e-59	41.60	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
tnfaip1	4.897e-59	41.60	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
kctd13	5.140e-59	44.40	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kctd10	1.304e-51	41.52	potassium channel tetramerization domain containin...	[more]
kctd6a	6.274e-17	43.62	potassium channel tetramerization domain containin...	[more]
kctd7	8.173e-15	40.00	potassium channel tetramerization domain containin...	[more]
KCTD9	4.969e-10	37.37	potassium channel tetramerization domain containin...	[more]
KCTD18	3.347e-8	42.62	potassium channel tetramerization domain containin...	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO37751	1.138e-55	43.51	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34594	3.369e-19	45.16	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49543	2.679e-16	44.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34699	2.680e-15	40.86	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32194	5.949e-15	44.66	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kctd10	1.678e-66	45.28	potassium channel tetramerization domain containin...	[more]
kctd13	9.586e-60	43.56	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
kctd13	4.353e-54	42.08	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
kctd13	6.696e-52	40.91	BTB/POZ domain-containing adapter for CUL3-mediate...	[more]
kctd7	8.600e-18	44.21	potassium channel tetramerization domain containin...	[more]

BLAST of BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000037805.1	0.000e+0	98.44	SMESG000037805.1	[more]
SMESG000037805.1	0.000e+0	99.04	SMESG000037805.1	[more]
SMESG000070841.1	1.917e-64	83.08	SMESG000070841.1	[more]
SMESG000042930.1	3.344e-11	32.71	SMESG000042930.1	[more]
SMESG000017037.1	1.226e-10	36.56	SMESG000017037.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30007705 ID=SMED30007705|Name=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3884bp
ATATATATATATATATATAAGCTGTCATTGTCGTTTGTCGAAAATGAAAT
AAATTGTAAGAAATTTATAAAAAGTGCAAAGTAATTTTAAATTAAAAATG
AAATAGTATTCACCAATTTGATTAAATAAAGTGTTACCATCATCATGTAA
AGAAATATTGTGAAAACTTGTGATGTAAATAAAATTTCAATATTCTGGGT
ATTGGTGATTGATTATGGAATGCGAGAAGTCAGGAAAATGTTCTACTTTA
AACTTATCAAGTCAAGCAGTAATTTAATTTTATAATTTCTATTAATGCGT
GAATCACTAAATCATTTATAAAAATGCAATGTCTCACATTTTAGTATTTA
TTATGAAATTGCAAAATTGATGCATAACTAACGGTTAACATACGAAATCC
TCTGCAAAAAATTTAATATTTTAGAGTCTGAAAGATTAAATCAGTTCATA
GTTGCTATATGATATGTCTAAGTTTCAGGCATATCAAGTAGCTACTACGA
ACTGATTTCTAAAGAAAAGCGCTAGTTAGCATTCATTCTAAAAGTTTTTT
GTTGATTAGATTTTGCTATTTGACAAATGAATATAAATAAAAATCTGTGG
GTAAAAGGAATTAATGTGTAAATAAGCAAAGAATTAATTAGTTTTTCTTT
CCAAATTTCACTATATTAAAATAGTTTTTGAATATCTCTGCACTGTTTTA
TATTGTAAACAATGTTATTCGGTTAATGAAAATCTTTGTACAAAATTGTT
AAACTGAGCAAGGACTAATTAAGAACTTAATGAAATGGTTTTTTCATGAA
TTTAAATATTCTGAATTTAAGGATATTCTTTCTAGTTTTTGAAGAGGAGG
AATTTTGCGTCTCCCTGATTTTATGATTTTTGGTTTCGGCATCTCGAATG
ATTCTTCATTGCGATCGTCTAAGATTTCAGTTTCCCATGGGGTTATACTT
GTAAATGTTTGATCTTTTATATCTGCAGAATTTTCGAACGAAATATTATT
GATTGATGGAGCCAAATGTCCTGTTGATACAGTGTTTGTCCTTCCATTTT
GGTTTTGAATTCTAGCGAAAGGTGAATAAATCATATCGATTAGTTTTATT
TCGTCAACGAGTGGATCGTTTTTTGTCGAATATGTCGCTTTAATAAGACA
TTTTGATTCGTCCTGCATAGGAATTCTGAAAAGTCTCTTTAGAATGTGGG
ATAGAGTTGGTTGTCGTACAGAGAAAAGTGTTTATTGAAGAGAGGGGTAA
ATTTAGTACATTTTCTCAATGTATTTTCTCCGAGTCATTTTTTTAATGCC
AGAGTTAAAGTTTTAAGGAAAATCCCATTCATCTGTTGCTCTGTGGATGG
TAAGGAGAAGTCTGATAAGTCATAAAAACTTCAACCTTAAAAACCTTTCG
TTCCATTTAATCCACATAGTACAAGATTGATATTCTCATCTACCACCTGC
TGCCATTGGTCTTGTGAGACAGCTAGTGGTTCGTCAGTCAAAGGTAGGCA
CTGTTGCCTGAACTACTTAGACTCGGACGCAACGCGTGCTTGCTTTTAGA
CACTAGATGATAGTCCTTTATCTTTTGTCTAATTAGCTGCTATTCCTACG
AGTGAAACAGAATTAACTTAGAGTTTATTTAGAGATACAACACAATAGAA
TATACGTAAGAGTTTATTTGACTATTTCGCTACTACTCTGCATACTTCTT
TATCTTTTTACAGAGTTCGATCTTCCCAACCCGACTGCTTCGGCCTCTGT
AATTCTCGGTACGTGACCTGGACTGGAGCGAAAAAAGTGTATACGGCACC
GCGTATTCCTCTTTTCACTTGGCTAAGGCTGTCTCTAAGGCTTTGCTCTG
TCCCTTGGATGGTCGATGTGATGTTTGATCCTGAACCAGCGAATCCCGCA
ATAACTGTCGCTTTTGGTTTCACTACAGTGACAATTGGATAATTCAAGTC
TAGAGTCTCCGTGTGTTTGTTCTACGTTCATCACAAGGACTAAGGATTCG
TGACGACTAAGCAAACTCAAATCACACTAGCACTGAATTTACTAATAAAA
ATACTAAGGAAACAAAGTGAATCTAAAGATAAAAGTGAAAATAAATGTCC
AAAAATTGAAAAGGAAACACTAAAAATACCAACTTGATTACATCAAAATA
ACAATCTTTCTTTACAAAACAAAACGGATATGAATTTTAAACGAAGACAT
TTAAGAATTTCTGACCGCTGAATTTAAAAGAATTCATCTAAAAAGGCAAT
ATTCCAAAGTTGCTGCTATCGAGGTTTCTGCAATTGTGCCTATAGATGTT
ATATACCGATTGAAGATTTATTGATGGTAGCATAGAATGTTCTCACCACC
TTACCAGTCTTCGTCGTGGAAGATTTATTGATGTAGCTACACCCACAGGT
CGACGTCATAATTCATTTTGAAGGGGTCTCAGAGTGCACTCGTTGGCACA
ACGTTATATAGAGGACCACAACTAACCCCTACGCTCCGAAAAAATGCTGC
TTCTCGCCACTCCCGAGCATTCCGGGTAGCAAAAGCGATTCTTTTTATTT
AGTATCACCATAGCGAGGAAACTCCGTTTTAATGCGCCGCCTTCCCACTT
AGATCCACGAAAAAGAGACTTCACCAACTGGTTAATTTCAAATTAAAGTT
ATTTTTTTCGTTTTATTAAATAATTTAATTATAAGAAAAAAAGGTTTGTT
TTACTGGATCAAATGTGGTGGTGGTTTTTACGTAGATTTTAATTTTGGAT
TAATGTAATTTATTGTAATAAAAGATTTTCAGGCTAATTAATTTTAAATA
TTTGATGTCAACAAGTTTGGATCAATCTGTTGAATACCTAAAGTTAAATG
TAGGAGGTTCCTTATTCTACACCACCATTGGAACTTTAAAAAATGCGTCA
GACAGTATGTTTAGTGCAATGTTTAGTGGCCGAATGGAAGTTAAAAAAGA
TTCAGAAGGCTGGGTTTTAATTGACAGATGTGGAAAGCATTTTAATCTTA
TTTTAAATTTTTTGAGAGATGGCGAAATTCCATTGTTCGATAATAGAAAC
GAGCTATCTGAATTATTAGTGGAGGCAAAATTTTATTGTTTGGAAAACCT
GGTTAAATCAATTGAAGCTAAAATCGGCCGTTTACATTGTGAGGAAGAAG
ATTTAACTAGTTCTCAAGCAACAATCATTATTGTGAAAGATAGTCGAATG
GCTAAGGTTTTAATTGCATCAACTTTAAAACCTGTTGTTAAACTCACCAT
GAACAGATATAATAATGTATTTTCTTATACAAGCAACTCCCATGACAATT
TGCTAAGAAATGTTGAGTGTTTAGAAAAATACGCTCTTATGTTTGCCGAT
ACAATCAGATTTGTAAAAGATGTTAGCGAAAAGTTTGAAAATAATCAAAT
ATGTGAATGGAGTTTCCATTATCGAGGCTACAAATTGCGATCTATTGACT
GCATGGCTATTCACTACAGCACTGAGAAACGATTGATCAAAGTTGAATTT
CACGAATCTCGAATCCACGAAGAAATGCTTATGCTCATTTCAGTTGCTAC
AAGAGATCTTTCAGACGCCGAACTCAGCGAAATTTCCAAAAGACAAAGCG
GAACACACAATCAGTCACCTTCAATAACTACTGCTCAAATGTCCTCAGAA
AGGGATGATCAAGAAGCAGAAATAAATTCATTGATCAGTATGCCAATCAA
TCAAAATGTTTCACAGAGAAGCACAATTTCATCCAGATTAAATAGACGTA
ATTGATTTTAATTCGATTTTATCCTCAAATTGTGAAATTTTATTGTATGA
CTGTTTTAAGATTTATAATTTGTGTGGTCTTTTTTATTCTCAATCGATAA
ATACGAAGCAATAAATTGTTTTAGATTTAGATGG

protein sequence of SMED30007705-orf-1

>SMED30007705-orf-1 ID=SMED30007705-orf-1|Name=SMED30007705-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=317bp
MSTSLDQSVEYLKLNVGGSLFYTTIGTLKNASDSMFSAMFSGRMEVKKDS
EGWVLIDRCGKHFNLILNFLRDGEIPLFDNRNELSELLVEAKFYCLENLV
KSIEAKIGRLHCEEEDLTSSQATIIIVKDSRMAKVLIASTLKPVVKLTMN
RYNNVFSYTSNSHDNLLRNVECLEKYALMFADTIRFVKDVSEKFENNQIC
EWSFHYRGYKLRSIDCMAIHYSTEKRLIKVEFHESRIHEEMLMLISVATR
DLSDAELSEISKRQSGTHNQSPSITTAQMSSERDDQEAEINSLISMPINQ
NVSQRSTISSRLNRRN*

protein sequence of SMED30007705-orf-2

>SMED30007705-orf-2 ID=SMED30007705-orf-2|Name=SMED30007705-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=125bp
MQDESKCLIKATYSTKNDPLVDEIKLIDMIYSPFARIQNQNGRTNTVSTG
HLAPSINNISFENSADIKDQTFTSITPWETEILDDRNEESFEMPKPKIIK
SGRRKIPPLQKLERISLNSEYLNS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000208	testis
PLANA:0000232	copulatory apparatus

Vocabulary: **INTERPRO**
Term	Definition
IPR000210	BTB/POZ_dom
IPR003131	T1-type_BTB
IPR011333	SKP1/BTB/POZ_sf

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

Vocabulary: **biological process**
Term	Definition
GO:0051260	protein homooligomerization

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 128..150
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 127..157
None	No IPR available	PANTHER	PTHR11145	TUMOR NECROSIS FACTOR-RELATED	coord: 5..137
None	No IPR available	PANTHER	PTHR11145:SF17	BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 2	coord: 5..137

Main menu

BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Owlery

blazegraph-runner