WTS
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30007679 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of WTS vs. Ensembl Human
Match: LATS1 (large tumor suppressor kinase 1 [Source:HGNC Symbol;Acc:HGNC:6514]) HSP 1 Score: 487.649 bits (1254), Expect = 1.112e-154 Identity = 274/552 (49.64%), Postives = 354/552 (64.13%), Query Frame = 3
Query: 984 PSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSE------DIENETKSSVLVSP---DDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQT--NPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
P+ Q PPP PK L H NP ++PP + I+ ++ + + + SE D ++ K + SP N E + I+ A+K FME +E V ++H++R R +QLE EM ++GL + ++QMR++L QKESNY+R+KR KM+KSMF +IK LG+GAFGEV L RK D K LYA K L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF E L RFY AE+T A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H QDS F D + D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VINW++ L+IP A L P A D+I + C P +RL EIK HPFF +ID+ +L Q A Y P I DTSNFD V+ D S D+ +D + N + + F+ FTF+RFFD
Sbjct: 550 PNYQGPPPPYPK---HLLHQNP-SVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQITTSPITVRKNKKDEERRES----RIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYK-NGKHPEHAFYEFTFRRFFD 1085
BLAST of WTS vs. Ensembl Human
Match: LATS1 (large tumor suppressor kinase 1 [Source:HGNC Symbol;Acc:HGNC:6514]) HSP 1 Score: 487.649 bits (1254), Expect = 1.112e-154 Identity = 274/552 (49.64%), Postives = 354/552 (64.13%), Query Frame = 3
Query: 984 PSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSE------DIENETKSSVLVSP---DDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQT--NPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
P+ Q PPP PK L H NP ++PP + I+ ++ + + + SE D ++ K + SP N E + I+ A+K FME +E V ++H++R R +QLE EM ++GL + ++QMR++L QKESNY+R+KR KM+KSMF +IK LG+GAFGEV L RK D K LYA K L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF E L RFY AE+T A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H QDS F D + D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VINW++ L+IP A L P A D+I + C P +RL EIK HPFF +ID+ +L Q A Y P I DTSNFD V+ D S D+ +D + N + + F+ FTF+RFFD
Sbjct: 550 PNYQGPPPPYPK---HLLHQNP-SVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQITTSPITVRKNKKDEERRES----RIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYK-NGKHPEHAFYEFTFRRFFD 1085
BLAST of WTS vs. Ensembl Human
Match: LATS2 (large tumor suppressor kinase 2 [Source:HGNC Symbol;Acc:HGNC:6515]) HSP 1 Score: 482.641 bits (1241), Expect = 4.363e-153 Identity = 248/464 (53.45%), Postives = 322/464 (69.40%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEI---VADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDWKNLI-NQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
I+ A+K FME +E V +T++++ +R QLE EM K GL +EQMR++L QKESNY R+KR KM+KSMF +IK LG+GAFGEV L K D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVVKL++SFQD+ SLY VM+YIPGGDMMSLLI+ +F E L RFY AE+TLA+ESVH +GF+HRDIKPDNIL+ DGHIKLTDFGLCTGFRWTH ++YY+ H+ QDS ++ V++ + D K L +R + R SLVGTPNYIAPE+L R+ Y + CDWWSVGVI++EMLVGQPPFLAP+ TQ +VINWE+ L+IPA L P A D+I + CC+ +RL ++K HPFF +ID+ + I Q APY P I +DTSNFD V+++ + S S + + + NN + + F+ FTF+RFFD
Sbjct: 594 IKSYSPYAFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQ-------KGSHVRQDSMEPSDLWDDVSNCRCG-DRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSADHRLGRNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPMDTSNFDPVDEESPWNDASEGSTKAWD--TLTSPNNKHPEHAFYEFTFRRFFD 1047
BLAST of WTS vs. Ensembl Human
Match: STK38 (serine/threonine kinase 38 [Source:HGNC Symbol;Acc:HGNC:17847]) HSP 1 Score: 359.762 bits (922), Expect = 7.515e-114 Identity = 187/450 (41.56%), Postives = 268/450 (59.56%), Query Frame = 3
Query: 1260 MENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPS--EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKS----RLNNNNTDIPFFNFTFKRF 2591
+EN + H+ER R ++LE M++ GL K R +KE+ +LR+KR ++ FE +K++G GAFGEV LV+KKD +YAMK L+K +++E+ Q H+RAERDIL EAD+ WVVK+F+SFQD+ +LYL+ME++PGGDMM+LL+KK E+ +FY AE LA++S+H LGF+HRDIKPDN+LL GH+KL+DFGLCTG + H ++Y++ + S S + T ++N + R+ S VGTP+YIAPE+ + YNK CDWWS+GVI+YEML+G PPF + + T +V+NW+ L P + A+D+I RFCC +R+ P EIK + FF +DW+++ + A I+ DTSNFD D PT + + N D F N+T+KRF
Sbjct: 27 LENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDF-----------------TFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEF-----------PESDILKPTVATSNHPETDYKNKDWVFINYTYKRF 448
BLAST of WTS vs. Ensembl Human
Match: STK38L (serine/threonine kinase 38 like [Source:HGNC Symbol;Acc:HGNC:17848]) HSP 1 Score: 358.221 bits (918), Expect = 2.804e-113 Identity = 188/446 (42.15%), Postives = 270/446 (60.54%), Query Frame = 3
Query: 1260 MENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRL--SDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRF 2591
+EN + H+ER R ++LE M++ GL K+ R +KE+ +LR+KR ++ FE +K++G GAFGEV LV+KKD +YAMK L+K +++E+ Q AH+RAERDIL EAD WVVK+F+SFQD+ +LYL+ME++PGGDMM+LL+KK E+ +FY +E LA++++H LGF+HRDIKPDN+LL GH+KL+DFGLCTG + H ++Y++ + S + FQ ++N + R+ S VGTP+YIAPE+ + YNK CDWWS+GVI+YEML+G PPF + + T +V+NW+ L P + A+D+I RFC + NR+ S EIK HPFF +DW+++ + A I+ DTSNFD S + P KS+ D F N+T+KRF
Sbjct: 28 LENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDF-------SFQ----------NMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDF----PESDILQPVPNTTEPDYKSK------DWVFLNYTYKRF 446
BLAST of WTS vs. Ensembl Celegans
Match: wts-1 (Serine/threonine-protein kinase WARTS homolog [Source:UniProtKB/Swiss-Prot;Acc:O45797]) HSP 1 Score: 395.586 bits (1015), Expect = 1.408e-122 Identity = 205/466 (43.99%), Postives = 286/466 (61.37%), Query Frame = 3
Query: 1257 FMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSD--------PSEIKQHPFFISIDWKNL--INQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIP---------FFNFTFKRFFD 2597
+ME +E++ + +KER RM+QLE EM L + +M LL QKES Y R++RQKM+KS F I +GVGAFG+V+LVRK D +++YAMK L+K +V+ ++Q AHV+AERDILAEAD+ W+V+LFFSFQD LY +MEY+PGGDMM+LLI+KGIFEEDL RFY AE+ A+E VH++GF+HRD+KPDNIL+ + GHIKLTDFGLCTG RWTH +YY + +H E+ A ++ LN + R SLVGT NY+APE++ + +N+SCDWWS GVI+YEM+ G+ PF + TQ+R+ NW +FL+ NL +I++ C+ ++RL +++K HP+F IDW NL + D Y P + + DTSNF++ + +N+ D P F+ FT++ FFD
Sbjct: 439 YMEQHVERLLQQYKEREKRMKQLEKEMVSAQLPDIMRNKMLGLLQQKESKYTRLRRQKMSKSHFTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYY-----GPENDHHRVDSFSLPPEVAAIDKSVKVLN------VRQQTRRITAHSLVGTGNYMAPEVIAKTGHNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNFLDFTYCGNLSKECLMMIQQLICDASSRLGSHGKDVAERTAQVKNHPWFRGIDWVNLRKLRADYIYIPRVTHDEDTSNFETFQ------------------------DNDRADKPNVRGLHNPAFYEFTYRHFFD 869
BLAST of WTS vs. Ensembl Celegans
Match: sax-1 (Serine/threonine-protein kinase sax-1 [Source:UniProtKB/Swiss-Prot;Acc:Q2L6W9]) HSP 1 Score: 363.999 bits (933), Expect = 1.091e-115 Identity = 191/434 (44.01%), Postives = 269/434 (61.98%), Query Frame = 3
Query: 1299 ERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPS---EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRF 2591
ER +R+++LE ++ GL KE+ R++ KE++YLR+KR ++ + FE +K++G GAFGEV LV+K D +YAMK L+K +VE+ QTAHVRAERDIL+EAD DWVVK+++SFQD ++LYLVME++PGGDMM+LLIKK E+ +FY AE LA++ +HSLGF+HRDIKPDN+LL GH+KL+DFGLCTG + H +Y++W PS IS+ E ++ + R + S VGTP+YIAPE+ + Y KSCDWWS+GVI+YEML+G PPF + T +VINW+ L P+ + A+ I+RFCC RL + EIKQ PF IDW ++ + P + ++ DTSNFD D+ + S + ++ P + F +FT+KRF
Sbjct: 38 ERENRLKKLEEDISARGLSDEEKEEKRKIHHSKETDYLRLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHYRNW-PSTLPPDFISKPFESKRK----------------AETWKRNRRAYAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINWQQTLVFPSDVPISIEAKATIKRFCCEAERRLGNHGGLDEIKQCPFVKRIDWNHIRERPPPIRVTVKSIDDTSNFDDFPDEDLTWPTSTLIRPEEQPGRRGE---------FVDFTYKRF 445
BLAST of WTS vs. Ensembl Celegans
Match: sax-1 (Serine/threonine-protein kinase sax-1 [Source:UniProtKB/Swiss-Prot;Acc:Q2L6W9]) HSP 1 Score: 363.614 bits (932), Expect = 1.277e-115 Identity = 191/434 (44.01%), Postives = 269/434 (61.98%), Query Frame = 3
Query: 1299 ERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPS---EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRF 2591
ER +R+++LE ++ GL KE+ R++ KE++YLR+KR ++ + FE +K++G GAFGEV LV+K D +YAMK L+K +VE+ QTAHVRAERDIL+EAD DWVVK+++SFQD ++LYLVME++PGGDMM+LLIKK E+ +FY AE LA++ +HSLGF+HRDIKPDN+LL GH+KL+DFGLCTG + H +Y++W PS IS+ E ++ + R + S VGTP+YIAPE+ + Y KSCDWWS+GVI+YEML+G PPF + T +VINW+ L P+ + A+ I+RFCC RL + EIKQ PF IDW ++ + P + ++ DTSNFD D+ + S + ++ P + F +FT+KRF
Sbjct: 38 ERENRLKKLEEDISARGLSDEEKEEKRKIHHSKETDYLRLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHYRNW-PSTLPPDFISKPFESKRK----------------AETWKRNRRAYAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINWQQTLVFPSDVPISIEAKATIKRFCCEAERRLGNHGGLDEIKQCPFVKRIDWNHIRERPPPIRVTVKSIDDTSNFDDFPDEDLTWPTSTLIRPEEQPGRRGE---------FVDFTYKRF 445
BLAST of WTS vs. Ensembl Celegans
Match: mrck-1 (Serine/threonine-protein kinase mrck-1 [Source:UniProtKB/Swiss-Prot;Acc:O01583]) HSP 1 Score: 248.44 bits (633), Expect = 1.024e-67 Identity = 133/360 (36.94%), Postives = 195/360 (54.17%), Query Frame = 3
Query: 1413 RMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIK-KGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILK-----REKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHA---NLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFD 2459
+ K+ ++++ FE +K++G GAFGEVA+VR + ++YAMK L K +V+R +TA R ERD+L D W+ L ++FQD+ +LY VM+Y GGDM++LL K E + +FY AEM LA++S+H LG+VHRD+KPDN+LL GHI+L DFG C I+ADG ++ VGTP+YI+PEIL+ R +Y K CDWWS+G+ +YEML G PF + T ++++ + L+ P + A+D+IR+ C+ R S+ + HPFF IDW + + + PY P + DTSNFD
Sbjct: 72 KAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCL--------------------------------RILADGSVASNV-------------------AVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSSPEDTSNFD 380
BLAST of WTS vs. Ensembl Celegans
Match: mrck-1 (Serine/threonine-protein kinase mrck-1 [Source:UniProtKB/Swiss-Prot;Acc:O01583]) HSP 1 Score: 248.44 bits (633), Expect = 1.024e-67 Identity = 133/360 (36.94%), Postives = 195/360 (54.17%), Query Frame = 3
Query: 1413 RMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIK-KGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILK-----REKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHA---NLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFD 2459
+ K+ ++++ FE +K++G GAFGEVA+VR + ++YAMK L K +V+R +TA R ERD+L D W+ L ++FQD+ +LY VM+Y GGDM++LL K E + +FY AEM LA++S+H LG+VHRD+KPDN+LL GHI+L DFG C I+ADG ++ VGTP+YI+PEIL+ R +Y K CDWWS+G+ +YEML G PF + T ++++ + L+ P + A+D+IR+ C+ R S+ + HPFF IDW + + + PY P + DTSNFD
Sbjct: 72 KAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCL--------------------------------RILADGSVASNV-------------------AVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSSPEDTSNFD 380
BLAST of WTS vs. Ensembl Fly
Match: wts (gene:FBgn0011739 transcript:FBtr0085720) HSP 1 Score: 465.692 bits (1197), Expect = 7.182e-147 Identity = 234/420 (55.71%), Postives = 302/420 (71.90%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKD-NKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDS-EGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXM--RSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDP-SEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVE 2468
IR+ A+K FME +E V +++++R R QLE EM K+GL + +MR++L QKESNY+R+KR KM+KSMF ++K +GVGAFGEV LV K D + LYAMK L+K +V++R Q AHV+AERDILAEADN+WVVKL++SFQD+ +LY VM+YIPGGD+MSLLIK GIFEE+L RFY AE+T A++SVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ + H QDS E ++E +G KP + + R ++ + + SLVGTPNYIAPE+L+R Y + CD+WSVGVI+YEMLVGQPPFLA S TQ +VINWE L+IP A L A D+IRR C + RL E+K H FF ID+ ++ Q APY P I+ DTSNFD V+
Sbjct: 645 IRQYSPQAFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQE------NGNHSRQDSMEPWEEYSENGP------KPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGKSVDEVKSHDFFKGIDFADMRKQKAPYIPEIKHPTDTSNFDPVD 1052
BLAST of WTS vs. Ensembl Fly
Match: trc (gene:FBgn0003744 transcript:FBtr0332154) HSP 1 Score: 334.339 bits (856), Expect = 1.580e-104 Identity = 170/410 (41.46%), Postives = 246/410 (60.00%), Query Frame = 3
Query: 1239 AAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDP---SEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFD 2459
A K +EN + + ER R+ +LE ++ L +++ R QKE+ YLR+KR ++ FE +K++G GAFGEV LV+KKD +YAMK L+K +++E+ Q AHVRAERD+L EAD+ WVVK+++SFQD +LYL+ME++PGGDMM+LL+KK E+ +FY +E LA++S+H LGF+HRDIKPDN+LL GH+KL+DFGLCTG + +H +Y+ + S F A +P ++ + R S VGTP+YIAPE+ + Y +CDWWS+GVI+YEML+G PPF + + T +V+NW L P + A++ I FCC RL ++K PFF +DW+++ + A +R DTSNFD
Sbjct: 24 ATKAKVTLENYYSNLVTQYGERKQRLAKLEAQLKDESLSEAQRQEKRLQHAQKETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSD---------FIGTCASLSCSP-MDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVEVRSIDDTSNFD 423
BLAST of WTS vs. Ensembl Fly
Match: trc (gene:FBgn0003744 transcript:FBtr0074922) HSP 1 Score: 333.954 bits (855), Expect = 2.147e-104 Identity = 168/410 (40.98%), Postives = 244/410 (59.51%), Query Frame = 3
Query: 1239 AAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDP---SEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFD 2459
A K +EN + + ER R+ +LE ++ L +++ R QKE+ YLR+KR ++ FE +K++G GAFGEV LV+KKD +YAMK L+K +++E+ Q AHVRAERD+L EAD+ WVVK+++SFQD +LYL+ME++PGGDMM+LL+KK E+ +FY +E LA++S+H LGF+HRDIKPDN+LL GH+KL+DFGLCTG + +H +Y+ + S + G ++ + R S VGTP+YIAPE+ + Y +CDWWS+GVI+YEML+G PPF + + T +V+NW L P + A++ I FCC RL ++K PFF +DW+++ + A +R DTSNFD
Sbjct: 24 ATKAKVTLENYYSNLVTQYGERKQRLAKLEAQLKDESLSEAQRQEKRLQHAQKETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFI--------------GTCASPMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVEVRSIDDTSNFD 419
BLAST of WTS vs. Ensembl Fly
Match: gek (gene:FBgn0023081 transcript:FBtr0072287) HSP 1 Score: 251.136 bits (640), Expect = 1.939e-68 Identity = 131/363 (36.09%), Postives = 198/363 (54.55%), Query Frame = 3
Query: 1416 MKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFE----EDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILK-----REKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLD----PNAEDIIRRFCCNPANRLSDPS--EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFD 2459
+++ ++++ F+ +K++G GAFGEV +V+ +++YAMK L K +++R +TA R ERD+L D W+ L ++FQD +LYLVM+Y GGD+++LL K FE ED+ +FY EM LA+ S+H + +VHRDIKPDN+LL K GH++L DFG C D T +++ VGTP+YI+PEIL+ + +Y CDWWS+GV +YEML G+ PF A S T +++N ++ N+P+ L+ ++D++ + C P NRL + HP+F+ IDWKN+ APY P + DTSNFD
Sbjct: 90 VRKLRLSRDDFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERDVLVFGDRQWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSK---FEDKLPEDMAKFYITEMILAINSIHQIRYVHRDIKPDNVLLDKRGHVRLADFGSCL------------RLDKDGTVQSNVA---------------------------------------VGTPDYISPEILRAMEDGKGRYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLICIPENRLGQNGIQDFMDHPWFVGIDWKNIRQGPAPYVPEVSSPTDTSNFD 398
BLAST of WTS vs. Ensembl Fly
Match: Rok (gene:FBgn0026181 transcript:FBtr0340153) HSP 1 Score: 237.269 bits (604), Expect = 4.497e-64 Identity = 130/363 (35.81%), Postives = 199/363 (54.82%), Query Frame = 3
Query: 1410 LRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFE--EDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKRE----KYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDWK--NLINQDAPYKPYIRDELDTSNFDSVE 2468
+++ + +MN F IKL+G GAFGEV LVR K + Q+YAMK+L K +++R +A ER I+A A+++W+V+L F+FQD LY+VM+++PGGD++SL+ G ++ E FY E+ LAL+++H++GFVHRD+KPDN+LL GH+KL DFG C + A+GQ + VGTP+YI+PE+L+ + +Y + CDWWSVG+ +YEML G+ PF A S T ++++ ++ L+ P + A+ +IR F + RL +IK HPFF + W N+ P P + + DT NF+ +E
Sbjct: 66 MQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLM---GDYDIPEKWAIFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCM--------------------------------RMGANGQVVSS-------------------NAVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSFDNIRESVPPVVPELSSDDDTRNFEDIE 374
BLAST of WTS vs. Ensembl Zebrafish
Match: lats1 (large tumor suppressor kinase 1 [Source:ZFIN;Acc:ZDB-GENE-050523-2]) HSP 1 Score: 491.5 bits (1264), Expect = 5.313e-157 Identity = 268/555 (48.29%), Postives = 348/555 (62.70%), Query Frame = 3
Query: 981 LPSVQNPPPIPPKPTRSLSHANPPTLPPRQP-ITTTTETNDCAD--------CIKPNSEDIENETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQ---EIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDWKNLINQ--DAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
+PS Q PPP P P L PP P + ++ D AD C +E E E K + SP + + G + A+K FME +E + + H++R R +QLE EM ++GL + +EQMR +L QKESNY+R+KR KM+K MFE+IK LG+GAFGEV L RK D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF+EDL +FY AE+ A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H+ QDS F E A+ + D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI+YEM+VGQPPFLA + TQ +VI W++ L+IP A L P A D+I + C P +RL EIK PFF +ID+ + Q APY P I DTSNFD V+ ++ + ++ ++ N + + F+ FTF+RFFD
Sbjct: 484 VPSYQGPPP--PYPKHLLQQQQPPPGYDSSPALKPCSKEGDAADNENDTDSTCSSERAEGSEEE-KKQITTSPVPVRRHKRDEERKGESRLPMYSPQAFKFFMEQHVENILKNHQQRMRRKKQLESEMQRVGLSGDAQEQMRMMLSQKESNYIRLKRAKMDKCMFEKIKTLGIGAFGEVCLARKVDTGALYAMKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFQEDLAQFYIAELICAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HVRQDSMDFSMEWEDSANCRCG-DRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILYEMVVGQPPFLATTPLETQMKVIRWQTSLHIPLQAKLSPEATDLILKLCRGPDDRLGRNGADEIKAQPFFRTIDFSKDLRQQHQAPYIPKITHSTDTSNFDPVD--PDKLWSEDADGNHNDTLTRWFKNGKHPEHAFYEFTFRRFFD 1025
BLAST of WTS vs. Ensembl Zebrafish
Match: lats1 (large tumor suppressor kinase 1 [Source:ZFIN;Acc:ZDB-GENE-050523-2]) HSP 1 Score: 491.5 bits (1264), Expect = 5.313e-157 Identity = 268/555 (48.29%), Postives = 348/555 (62.70%), Query Frame = 3
Query: 981 LPSVQNPPPIPPKPTRSLSHANPPTLPPRQP-ITTTTETNDCAD--------CIKPNSEDIENETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQ---EIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDWKNLINQ--DAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
+PS Q PPP P P L PP P + ++ D AD C +E E E K + SP + + G + A+K FME +E + + H++R R +QLE EM ++GL + +EQMR +L QKESNY+R+KR KM+K MFE+IK LG+GAFGEV L RK D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF+EDL +FY AE+ A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H+ QDS F E A+ + D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI+YEM+VGQPPFLA + TQ +VI W++ L+IP A L P A D+I + C P +RL EIK PFF +ID+ + Q APY P I DTSNFD V+ ++ + ++ ++ N + + F+ FTF+RFFD
Sbjct: 484 VPSYQGPPP--PYPKHLLQQQQPPPGYDSSPALKPCSKEGDAADNENDTDSTCSSERAEGSEEE-KKQITTSPVPVRRHKRDEERKGESRLPMYSPQAFKFFMEQHVENILKNHQQRMRRKKQLESEMQRVGLSGDAQEQMRMMLSQKESNYIRLKRAKMDKCMFEKIKTLGIGAFGEVCLARKVDTGALYAMKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFQEDLAQFYIAELICAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HVRQDSMDFSMEWEDSANCRCG-DRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILYEMVVGQPPFLATTPLETQMKVIRWQTSLHIPLQAKLSPEATDLILKLCRGPDDRLGRNGADEIKAQPFFRTIDFSKDLRQQHQAPYIPKITHSTDTSNFDPVD--PDKLWSEDADGNHNDTLTRWFKNGKHPEHAFYEFTFRRFFD 1025
BLAST of WTS vs. Ensembl Zebrafish
Match: lats2 (large tumor suppressor kinase 2 [Source:ZFIN;Acc:ZDB-GENE-050119-6]) HSP 1 Score: 488.804 bits (1257), Expect = 3.999e-156 Identity = 249/464 (53.66%), Postives = 320/464 (68.97%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDS---EGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
I+ A+K +ME +E V +T++++ +R QLE EM K GL +EQMR++L QKESNY R++R KM+KSMF +IK LG+GAFGEV L RK D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ G+F E L RFY AE+TLA+ESVH +GF+HRDIKPDNIL+ DGHIKLTDFGLCTGFRWTH ++YY+ + HI QDS F + V++ + L L +R R R SLVGTPNYIAPE+L R+ Y + CDWWSVGVI++EMLVGQPPFLAP+ TQ +VINWE+ L +P L P A DII + CC+ RL EIK HPFF +D+ NL Q APY+P I +DTSNFD VE++ G + S+S + + + + F+ FTF+RFFD
Sbjct: 548 IKSYSPFAFKFYMEQHVENVMKTYQQKLNRRMQLEQEMSKAGLSEAEQEQMRKMLYQKESNYNRLRRAKMDKSMFVKIKTLGIGAFGEVCLTRKVDTGALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVRLYYSFQDRDNLYFVMDYIPGGDMMSLLIRMGVFPEVLARFYVAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGN-------HIRQDSMEPSDFWDDVSNCRCGDRLMT-LEQRATRQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLQVPPQVKLSPEAVDIIGQLCCSAEERLGGNGAGEIKAHPFFSEVDFSSNLRTQPAPYRPKIAHPMDTSNFDPVEEEGGPGAWSDSGDSTRTWDTLCSPHGKHPEHAFYEFTFRRFFD 1003
BLAST of WTS vs. Ensembl Zebrafish
Match: lats2 (large tumor suppressor kinase 2 [Source:ZFIN;Acc:ZDB-GENE-050119-6]) HSP 1 Score: 489.574 bits (1259), Expect = 5.077e-156 Identity = 249/464 (53.66%), Postives = 320/464 (68.97%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDS---EGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
I+ A+K +ME +E V +T++++ +R QLE EM K GL +EQMR++L QKESNY R++R KM+KSMF +IK LG+GAFGEV L RK D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ G+F E L RFY AE+TLA+ESVH +GF+HRDIKPDNIL+ DGHIKLTDFGLCTGFRWTH ++YY+ + HI QDS F + V++ + L L +R R R SLVGTPNYIAPE+L R+ Y + CDWWSVGVI++EMLVGQPPFLAP+ TQ +VINWE+ L +P L P A DII + CC+ RL EIK HPFF +D+ NL Q APY+P I +DTSNFD VE++ G + S+S + + + + F+ FTF+RFFD
Sbjct: 572 IKSYSPFAFKFYMEQHVENVMKTYQQKLNRRMQLEQEMSKAGLSEAEQEQMRKMLYQKESNYNRLRRAKMDKSMFVKIKTLGIGAFGEVCLTRKVDTGALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVRLYYSFQDRDNLYFVMDYIPGGDMMSLLIRMGVFPEVLARFYVAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGN-------HIRQDSMEPSDFWDDVSNCRCGDRLMT-LEQRATRQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLQVPPQVKLSPEAVDIIGQLCCSAEERLGGNGAGEIKAHPFFSEVDFSSNLRTQPAPYRPKIAHPMDTSNFDPVEEEGGPGAWSDSGDSTRTWDTLCSPHGKHPEHAFYEFTFRRFFD 1027
BLAST of WTS vs. Ensembl Zebrafish
Match: lats2 (large tumor suppressor kinase 2 [Source:ZFIN;Acc:ZDB-GENE-050119-6]) HSP 1 Score: 490.345 bits (1261), Expect = 8.745e-156 Identity = 249/464 (53.66%), Postives = 320/464 (68.97%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDS---EGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
I+ A+K +ME +E V +T++++ +R QLE EM K GL +EQMR++L QKESNY R++R KM+KSMF +IK LG+GAFGEV L RK D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ G+F E L RFY AE+TLA+ESVH +GF+HRDIKPDNIL+ DGHIKLTDFGLCTGFRWTH ++YY+ + HI QDS F + V++ + L L +R R R SLVGTPNYIAPE+L R+ Y + CDWWSVGVI++EMLVGQPPFLAP+ TQ +VINWE+ L +P L P A DII + CC+ RL EIK HPFF +D+ NL Q APY+P I +DTSNFD VE++ G + S+S + + + + F+ FTF+RFFD
Sbjct: 634 IKSYSPFAFKFYMEQHVENVMKTYQQKLNRRMQLEQEMSKAGLSEAEQEQMRKMLYQKESNYNRLRRAKMDKSMFVKIKTLGIGAFGEVCLTRKVDTGALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVRLYYSFQDRDNLYFVMDYIPGGDMMSLLIRMGVFPEVLARFYVAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGN-------HIRQDSMEPSDFWDDVSNCRCGDRLMT-LEQRATRQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLQVPPQVKLSPEAVDIIGQLCCSAEERLGGNGAGEIKAHPFFSEVDFSSNLRTQPAPYRPKIAHPMDTSNFDPVEEEGGPGAWSDSGDSTRTWDTLCSPHGKHPEHAFYEFTFRRFFD 1089
BLAST of WTS vs. Ensembl Xenopus
Match: LATS1 (large tumor suppressor kinase 1 [Source:NCBI gene;Acc:100145677]) HSP 1 Score: 488.419 bits (1256), Expect = 4.260e-155 Identity = 276/586 (47.10%), Postives = 357/586 (60.92%), Query Frame = 3
Query: 885 ACDSSRPLFLT-NIYKDPIIFQQMDEHTNRNYIL--PSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIENETKSSVLVSPDD---NSAVPEHQSKDGY----LNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQT--NPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPS--EIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
A + P ++T N+ P FQ+ H + P+ Q PPP PK L N P + D A E++E T+ + ++ S VP ++K I+ A+K FME +E + ++H +R R +QLE EM ++GL ++QMR++L QKESNY+R+KR KM KSMF +IK LG+GAFGEV L RK D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ G+F EDL RFY AE+T A+ESVH + F+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H+ QDS F D D KPL R R R SLVGTPNYIAPE+L R Y + CDWWSVGVI+YEMLVGQPPFLA S TQ +VI W++ L+IPA A L P A D+I + C P +RL EIK HPFF +ID+ +L Q APY P I DTSNFD V+ + + + +D + N + + F+ FTF+RFFD
Sbjct: 502 ALAPTHPTWMTPNVQPGP--FQEGVSHNTSAQLAEAPNYQGPPPPYPK---HLLQQNTTVYEP----GLKSSKEDAAGVSTCTQEEMEKNTEPTTGITEKKQITTSPVPVRRNKRDEERRESQIQSYSPQAFKFFMEQHVENILKSHHQRLHRKKQLENEMMRVGLSQEAQDQMRKMLCQKESNYIRLKRAKMEKSMFVKIKTLGIGAFGEVCLARKTDTNALYAMKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGVFPEDLARFYIAELTCAVESVHKMDFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HLRQDSMDFSNEWGDPANCRCGDRLKPLEWRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILYEMLVGQPPFLAQSPVETQMKVIKWQTTLHIPAQAKLSPEASDLIVKLCRGPEDRLGKNGVDEIKVHPFFKNIDFSSDLRQQPAPYTPTITHPTDTSNFDPVDPEKLWNDEDKDGNKNDTLNGWYK-NGKHPEHAFYEFTFRRFFD 1070
BLAST of WTS vs. Ensembl Xenopus
Match: lats2 (large tumor suppressor kinase 2 [Source:NCBI gene;Acc:100124721]) HSP 1 Score: 486.108 bits (1250), Expect = 7.350e-154 Identity = 254/467 (54.39%), Postives = 327/467 (70.02%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEI---VADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDWKNLI-NQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFF-DHG 2603
I+ AYK +ME +E V +T++++ +R QLE EM + GL +EQMR++L QKESNY R+KR KM+KS+F +IK LG+GAFGEV L K D K LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVVKL++SFQD+ SLY VM+YIPGGDMMSLLI+ +F E L RFY AE+TLA+ESVH +GF+HRDIKPDNIL+ DGHIKLTDFGLCTGFRWTH ++YY+ + H QDS E+ V++ + D K L +R R +R SLVGTPNYIAPE+L R+ Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VI+WE+ L+IP+ NL P A ++I CC +RL P EIK HPFFIS+D+ + I +Q APY P I +DTSNFD VE++ + +S+ D S N +T+ F+ FTF+RFF DHG
Sbjct: 665 IKSYSPFAYKFYMEQHVENVLKTYQQKINRRLQLEQEMAEAGLCEAIQEQMRKILYQKESNYNRLKRAKMDKSLFVKIKTLGIGAFGEVCLASKVDTKALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGN-------HARQDSMEPSELWDDVSNCRCG-DRLKTLEQRAKRQHHRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLASNPTETQLKVIHWENTLHIPSQINLSPEATNLITALCCGAEDRLGRNGPDEIKAHPFFISMDFSSDIRHQPAPYVPKISHPMDTSNFDPVEEENPCNDSGDSTVTWDTLMSS---GNKHTEHAFYEFTFRRFFDDHG 1120
BLAST of WTS vs. Ensembl Xenopus
Match: ENSXETT00000012893.1 (serine/threonine kinase 38 [Source:NCBI gene;Acc:100379821]) HSP 1 Score: 357.066 bits (915), Expect = 6.627e-113 Identity = 190/449 (42.32%), Postives = 271/449 (60.36%), Query Frame = 3
Query: 1251 KRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPS--EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRF 2591
K +EN + H+ER R ++LE MD+ GL K R +KE+ +LR+KR ++ FE +K++G GAFGEV LV+KKD +YAMK L+K +++E+ Q H+RAERDIL EAD+ WVVK+F+SFQD+ +LYL+ME++PGGDMM+LL+KK E+ +FY AE LA++S+H LGF+HRDIKPDN+LL GH+KL+DFGLCTG + H +Y++ + S S ++ FQ ++N + R+ S VGTP+YIAPE+ + YNK CDWWS+GVI+YEML+G PPF + + T +V+NW+ L P + A+D+I RFCC R+ P EIK + FF +DW+++ + A I+ DTSNFD S ++P S+ + N D F N+T+KRF
Sbjct: 24 KMTLENFYSNLITQHEERELRQKRLEKAMDEEGLRDEEKRMRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKTDMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTDFYRNLNHSLPSDFN-------FQ----------NMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFLQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLIFPPEVPISEKAKDLILRFCCEWEQRVGAPGVEEIKTNHFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDEF---PDSDILKPMGAVSNHPESEFK----NKDWVFINYTYKRF 448
BLAST of WTS vs. Ensembl Xenopus
Match: ENSXETT00000029036.1 (serine/threonine kinase 38 [Source:NCBI gene;Acc:100379821]) HSP 1 Score: 354.369 bits (908), Expect = 9.875e-112 Identity = 188/453 (41.50%), Postives = 270/453 (59.60%), Query Frame = 3
Query: 1260 MENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPS--EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSV-------EXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRF 2591
+EN + H+ER R ++LE MD+ GL K R +KE+ +LR+KR ++ FE +K++G GAFGEV LV+KKD +YAMK L+K +++E+ Q H+RAERDIL EAD+ WVVK+F+SFQD+ +LYL+ME++PGGDMM+LL+KK E+ +FY AE LA++S+H LGF+HRDIKPDN+LL GH+KL+DFGLCTG + H +Y++ + S S ++ FQ ++N + R+ S VGTP+YIAPE+ + YNK CDWWS+GVI+YEML+G PPF + + T +V+NW+ L P + A+D+I RFCC R+ P EIK + FF +DW+++ + A I+ DTSNFD + ++P S+ + N D F N+T+KRF
Sbjct: 27 LENFYSNLITQHEERELRQKRLEKAMDEEGLRDEEKRMRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKTDMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTDFYRNLNHSLPSDFN-------FQ----------NMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFLQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLIFPPEVPISEKAKDLILRFCCEWEQRVGAPGVEEIKTNHFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDEFPDSDILKPMGKNLFFVTFLGAVSNHPESEFK----NKDWVFINYTYKRF 458
BLAST of WTS vs. Ensembl Xenopus
Match: ENSXETT00000029007.1 (serine/threonine kinase 38 [Source:NCBI gene;Acc:100379821]) HSP 1 Score: 352.443 bits (903), Expect = 3.330e-111 Identity = 179/405 (44.20%), Postives = 254/405 (62.72%), Query Frame = 3
Query: 1251 KRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPS--EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFD 2459
K +EN + H+ER R ++LE MD+ GL K R +KE+ +LR+KR ++ FE +K++G GAFGEV LV+KKD +YAMK L+K +++E+ Q H+RAERDIL EAD+ WVVK+F+SFQD+ +LYL+ME++PGGDMM+LL+KK E+ +FY AE LA++S+H LGF+HRDIKPDN+LL GH+KL+DFGLCTG + H +Y++ + S S ++ FQ ++N + R+ S VGTP+YIAPE+ + YNK CDWWS+GVI+YEML+G PPF + + T +V+NW+ L P + A+D+I RFCC R+ P EIK + FF +DW+++ + A I+ DTSNFD
Sbjct: 21 KMTLENFYSNLITQHEERELRQKRLEKAMDEEGLRDEEKRMRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKTDMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTDFYRNLNHSLPSDFN-------FQ----------NMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFLQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLIFPPEVPISEKAKDLILRFCCEWEQRVGAPGVEEIKTNHFFEGVDWEHIRERPAAIPIEIKSIDDTSNFD 408
BLAST of WTS vs. Ensembl Mouse
Match: Lats1 (large tumor suppressor [Source:MGI Symbol;Acc:MGI:1333883]) HSP 1 Score: 488.419 bits (1256), Expect = 3.687e-155 Identity = 274/552 (49.64%), Postives = 351/552 (63.59%), Query Frame = 3
Query: 984 PSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSE------DIENETKSSVLVSP---DDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQT--NPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
PS Q PPP PK L H NP ++PP + ++ + + + +SE D ++ K + SP N E + I+ A+K FME +E V ++H++R R +QLE EM ++GL + ++QMR++L QKESNY+R+KR KM+KSMF +IK LG+GAFGEV L RK D K LYA K L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF E+L RFY AE+T A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H QDS F D D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VINW++ L+IP A L P A D+I + C P +RL EIK HPFF +ID+ +L Q A Y P I DTSNFD V+ D S S D + N + + F+ FTF+RFFD
Sbjct: 549 PSYQGPPPPYPK---HLLHQNP-SVPPYESVSKPCKDEQPSLPKEDDSEKSADSGDSGDKEKKQITTSPITVRKNKKDEERRES----RIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HPRQDSMDFSNEWGDPSNCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDGSEEENISDTLNGWYK-NGKHPEHAFYEFTFRRFFD 1084
BLAST of WTS vs. Ensembl Mouse
Match: Lats1 (large tumor suppressor [Source:MGI Symbol;Acc:MGI:1333883]) HSP 1 Score: 488.419 bits (1256), Expect = 3.687e-155 Identity = 274/552 (49.64%), Postives = 351/552 (63.59%), Query Frame = 3
Query: 984 PSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSE------DIENETKSSVLVSP---DDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQT--NPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
PS Q PPP PK L H NP ++PP + ++ + + + +SE D ++ K + SP N E + I+ A+K FME +E V ++H++R R +QLE EM ++GL + ++QMR++L QKESNY+R+KR KM+KSMF +IK LG+GAFGEV L RK D K LYA K L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF E+L RFY AE+T A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H QDS F D D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VINW++ L+IP A L P A D+I + C P +RL EIK HPFF +ID+ +L Q A Y P I DTSNFD V+ D S S D + N + + F+ FTF+RFFD
Sbjct: 549 PSYQGPPPPYPK---HLLHQNP-SVPPYESVSKPCKDEQPSLPKEDDSEKSADSGDSGDKEKKQITTSPITVRKNKKDEERRES----RIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HPRQDSMDFSNEWGDPSNCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDGSEEENISDTLNGWYK-NGKHPEHAFYEFTFRRFFD 1084
BLAST of WTS vs. Ensembl Mouse
Match: Lats1 (large tumor suppressor [Source:MGI Symbol;Acc:MGI:1333883]) HSP 1 Score: 488.419 bits (1256), Expect = 3.687e-155 Identity = 274/552 (49.64%), Postives = 351/552 (63.59%), Query Frame = 3
Query: 984 PSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSE------DIENETKSSVLVSP---DDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQT--NPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
PS Q PPP PK L H NP ++PP + ++ + + + +SE D ++ K + SP N E + I+ A+K FME +E V ++H++R R +QLE EM ++GL + ++QMR++L QKESNY+R+KR KM+KSMF +IK LG+GAFGEV L RK D K LYA K L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF E+L RFY AE+T A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H QDS F D D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VINW++ L+IP A L P A D+I + C P +RL EIK HPFF +ID+ +L Q A Y P I DTSNFD V+ D S S D + N + + F+ FTF+RFFD
Sbjct: 549 PSYQGPPPPYPK---HLLHQNP-SVPPYESVSKPCKDEQPSLPKEDDSEKSADSGDSGDKEKKQITTSPITVRKNKKDEERRES----RIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HPRQDSMDFSNEWGDPSNCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDGSEEENISDTLNGWYK-NGKHPEHAFYEFTFRRFFD 1084
BLAST of WTS vs. Ensembl Mouse
Match: Lats1 (large tumor suppressor [Source:MGI Symbol;Acc:MGI:1333883]) HSP 1 Score: 488.419 bits (1256), Expect = 3.687e-155 Identity = 274/552 (49.64%), Postives = 351/552 (63.59%), Query Frame = 3
Query: 984 PSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSE------DIENETKSSVLVSP---DDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQT--NPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
PS Q PPP PK L H NP ++PP + ++ + + + +SE D ++ K + SP N E + I+ A+K FME +E V ++H++R R +QLE EM ++GL + ++QMR++L QKESNY+R+KR KM+KSMF +IK LG+GAFGEV L RK D K LYA K L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF E+L RFY AE+T A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H QDS F D D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VINW++ L+IP A L P A D+I + C P +RL EIK HPFF +ID+ +L Q A Y P I DTSNFD V+ D S S D + N + + F+ FTF+RFFD
Sbjct: 549 PSYQGPPPPYPK---HLLHQNP-SVPPYESVSKPCKDEQPSLPKEDDSEKSADSGDSGDKEKKQITTSPITVRKNKKDEERRES----RIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HPRQDSMDFSNEWGDPSNCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDGSEEENISDTLNGWYK-NGKHPEHAFYEFTFRRFFD 1084
BLAST of WTS vs. Ensembl Mouse
Match: Lats1 (large tumor suppressor [Source:MGI Symbol;Acc:MGI:1333883]) HSP 1 Score: 488.419 bits (1256), Expect = 3.687e-155 Identity = 274/552 (49.64%), Postives = 351/552 (63.59%), Query Frame = 3
Query: 984 PSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSE------DIENETKSSVLVSP---DDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQT--NPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
PS Q PPP PK L H NP ++PP + ++ + + + +SE D ++ K + SP N E + I+ A+K FME +E V ++H++R R +QLE EM ++GL + ++QMR++L QKESNY+R+KR KM+KSMF +IK LG+GAFGEV L RK D K LYA K L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF E+L RFY AE+T A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H QDS F D D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VINW++ L+IP A L P A D+I + C P +RL EIK HPFF +ID+ +L Q A Y P I DTSNFD V+ D S S D + N + + F+ FTF+RFFD
Sbjct: 549 PSYQGPPPPYPK---HLLHQNP-SVPPYESVSKPCKDEQPSLPKEDDSEKSADSGDSGDKEKKQITTSPITVRKNKKDEERRES----RIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HPRQDSMDFSNEWGDPSNCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDGSEEENISDTLNGWYK-NGKHPEHAFYEFTFRRFFD 1084
BLAST of WTS vs. UniProt/SwissProt
Match: sp|Q8BYR2|LATS1_MOUSE (Serine/threonine-protein kinase LATS1 OS=Mus musculus OX=10090 GN=Lats1 PE=1 SV=3) HSP 1 Score: 488.419 bits (1256), Expect = 2.579e-154 Identity = 274/552 (49.64%), Postives = 351/552 (63.59%), Query Frame = 3
Query: 984 PSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSE------DIENETKSSVLVSP---DDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQT--NPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
PS Q PPP PK L H NP ++PP + ++ + + + +SE D ++ K + SP N E + I+ A+K FME +E V ++H++R R +QLE EM ++GL + ++QMR++L QKESNY+R+KR KM+KSMF +IK LG+GAFGEV L RK D K LYA K L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF E+L RFY AE+T A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H QDS F D D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VINW++ L+IP A L P A D+I + C P +RL EIK HPFF +ID+ +L Q A Y P I DTSNFD V+ D S S D + N + + F+ FTF+RFFD
Sbjct: 549 PSYQGPPPPYPK---HLLHQNP-SVPPYESVSKPCKDEQPSLPKEDDSEKSADSGDSGDKEKKQITTSPITVRKNKKDEERRES----RIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HPRQDSMDFSNEWGDPSNCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDGSEEENISDTLNGWYK-NGKHPEHAFYEFTFRRFFD 1084
BLAST of WTS vs. UniProt/SwissProt
Match: sp|O95835|LATS1_HUMAN (Serine/threonine-protein kinase LATS1 OS=Homo sapiens OX=9606 GN=LATS1 PE=1 SV=1) HSP 1 Score: 487.649 bits (1254), Expect = 5.338e-154 Identity = 274/552 (49.64%), Postives = 354/552 (64.13%), Query Frame = 3
Query: 984 PSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSE------DIENETKSSVLVSP---DDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQT--NPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
P+ Q PPP PK L H NP ++PP + I+ ++ + + + SE D ++ K + SP N E + I+ A+K FME +E V ++H++R R +QLE EM ++GL + ++QMR++L QKESNY+R+KR KM+KSMF +IK LG+GAFGEV L RK D K LYA K L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF E L RFY AE+T A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H QDS F D + D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VINW++ L+IP A L P A D+I + C P +RL EIK HPFF +ID+ +L Q A Y P I DTSNFD V+ D S D+ +D + N + + F+ FTF+RFFD
Sbjct: 550 PNYQGPPPPYPK---HLLHQNP-SVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQITTSPITVRKNKKDEERRES----RIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYK-NGKHPEHAFYEFTFRRFFD 1085
BLAST of WTS vs. UniProt/SwissProt
Match: sp|Q9NRM7|LATS2_HUMAN (Serine/threonine-protein kinase LATS2 OS=Homo sapiens OX=9606 GN=LATS2 PE=1 SV=2) HSP 1 Score: 482.641 bits (1241), Expect = 2.095e-152 Identity = 248/464 (53.45%), Postives = 322/464 (69.40%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEI---VADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDWKNLI-NQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
I+ A+K FME +E V +T++++ +R QLE EM K GL +EQMR++L QKESNY R+KR KM+KSMF +IK LG+GAFGEV L K D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVVKL++SFQD+ SLY VM+YIPGGDMMSLLI+ +F E L RFY AE+TLA+ESVH +GF+HRDIKPDNIL+ DGHIKLTDFGLCTGFRWTH ++YY+ H+ QDS ++ V++ + D K L +R + R SLVGTPNYIAPE+L R+ Y + CDWWSVGVI++EMLVGQPPFLAP+ TQ +VINWE+ L+IPA L P A D+I + CC+ +RL ++K HPFF +ID+ + I Q APY P I +DTSNFD V+++ + S S + + + NN + + F+ FTF+RFFD
Sbjct: 594 IKSYSPYAFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQ-------KGSHVRQDSMEPSDLWDDVSNCRCG-DRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSADHRLGRNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPMDTSNFDPVDEESPWNDASEGSTKAWD--TLTSPNNKHPEHAFYEFTFRRFFD 1047
BLAST of WTS vs. UniProt/SwissProt
Match: sp|Q7TSJ6|LATS2_MOUSE (Serine/threonine-protein kinase LATS2 OS=Mus musculus OX=10090 GN=Lats2 PE=1 SV=1) HSP 1 Score: 474.552 bits (1220), Expect = 7.354e-150 Identity = 246/468 (52.56%), Postives = 319/468 (68.16%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEI---VADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXX----XXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
I+ A+K FME +E V +T++++ R QLE EM K GL +EQMR++L QKESNY R+KR KM+KSMF +IK LG+GAFGEV L K D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVVKL++SFQD+ SLY VM+YIPGGDMMSLLI+ +F E L RFY AE+TLA+ESVH +GF+HRDIKPDNIL+ DGHIKLTDFGLCTGFRWTH ++YY+ + H+ QDS ++ V++ + D K L +R + R SLVGTPNYIAPE+L R+ Y + CDWWSVGVI++EMLVGQPPFLAP+ TQ +VINWES L+IP L A D+I + CC RL ++K HPFF +ID+ +++ Q APY P I +DTSNFD V+++ S + + +P+SK + + F+ FTF+RFFD
Sbjct: 552 IKSYSPYAFKFFMEQHVENVIKTYQQKVSRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKLDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGN-------HMRQDSMEPGDLWDDVSNCRCG-DRLKTLEQRAQKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWESTLHIPTQVRLSAEARDLITKLCCAADCRLGRDGADDLKAHPFFNTIDFSRDIRKQPAPYVPTISHPMDTSNFDPVDEESPWHEASGESAKAWDTLASPSSK------HPEHAFYEFTFRRFFD 1005
BLAST of WTS vs. UniProt/SwissProt
Match: sp|Q9VA38|WARTS_DROME (Serine/threonine-protein kinase Warts OS=Drosophila melanogaster OX=7227 GN=wts PE=1 SV=1) HSP 1 Score: 465.692 bits (1197), Expect = 7.199e-146 Identity = 234/420 (55.71%), Postives = 302/420 (71.90%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKD-NKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDS-EGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXM--RSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDP-SEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVE 2468
IR+ A+K FME +E V +++++R R QLE EM K+GL + +MR++L QKESNY+R+KR KM+KSMF ++K +GVGAFGEV LV K D + LYAMK L+K +V++R Q AHV+AERDILAEADN+WVVKL++SFQD+ +LY VM+YIPGGD+MSLLIK GIFEE+L RFY AE+T A++SVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ + H QDS E ++E +G KP + + R ++ + + SLVGTPNYIAPE+L+R Y + CD+WSVGVI+YEMLVGQPPFLA S TQ +VINWE L+IP A L A D+IRR C + RL E+K H FF ID+ ++ Q APY P I+ DTSNFD V+
Sbjct: 645 IRQYSPQAFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQE------NGNHSRQDSMEPWEEYSENGP------KPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGKSVDEVKSHDFFKGIDFADMRKQKAPYIPEIKHPTDTSNFDPVD 1052
BLAST of WTS vs. TrEMBL
Match: W8E0T0 (WTS OS=Schmidtea mediterranea OX=79327 GN=wts PE=2 SV=1) HSP 1 Score: 1584.7 bits (4102), Expect = 0.000e+0 Identity = 838/838 (100.00%), Postives = 838/838 (100.00%), Query Frame = 3
Query: 96 MDHYSNENVSLITKTASFPMYPMSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAXXXXXXXXXXXXXXXXXXXXXXXNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIENETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS 2609
MDHYSNENVSLITKTASFPMYPMSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAPPLPPKLSPQPSLQPSLEELSSSNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIENETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIRRKNRFKNRKFMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEDDIGSSSDSNSSQDDDNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS
Sbjct: 1 MDHYSNENVSLITKTASFPMYPMSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAPPLPPKLSPQPSLQPSLEELSSSNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIENETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIRRKNRFKNRKFMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEDDIGSSSDSNSSQDDDNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS 838
BLAST of WTS vs. TrEMBL
Match: A0A0X3NH08 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR116276 PE=4 SV=1) HSP 1 Score: 521.161 bits (1341), Expect = 1.192e-165 Identity = 270/473 (57.08%), Postives = 333/473 (70.40%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDP------SATSSYHISQDSEGFQE--IVADGQTNPDL----NKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFDHGN 2606
++ V A Y+RF+E + V R HKER +R +LE EM MGL + QMR++L KESNY+RM+R +M++SMF RIK LGVGAFG V LVRKK+N+QLYAMK LKKR+VV RRQ AHV+AERDILAEAD+DWVVKLFFSFQD +LYLVMEYIPGGDMMSLLIKK IFEEDL RFY AE+ LALESVH LGF+HRDIKPDNIL+ +DGHIKLTDFGLCT FRWTH ++Y WDP S S+ + E Q+ DG+ + +L ++ L RR NR+ RSLVGTPNYIAPEIL+R++YN++CDWWSVGVI+YEMLVG+PPF+A +A TQ RV+ W L IP L +A D+I+R C+P +RL+DP ++K+H FF I+W+ L Q PY P I DELDTSNFD+V+DD+ S + + F +FTFKRFFD N
Sbjct: 533 VKPVLPAVYRRFIEQKFANVGRIHKEREERQARLEAEMALMGLSETSRAQMRKMLQTKESNYMRMQRARMDESMFIRIKRLGVGAFGWVWLVRKKENRQLYAMKILKKRDVVRRRQLAHVQAERDILAEADSDWVVKLFFSFQDSHALYLVMEYIPGGDMMSLLIKKEIFEEDLTRFYIAELILALESVHRLGFIHRDIKPDNILINRDGHIKLTDFGLCTSFRWTHSSKY---WDPIFSTPQSGESNKEDANTGECPQQEACSVDGERDDELHPMHDQTLDRRVRSSSNRRCARSLVGTPNYIAPEILRRQEYNQACDWWSVGVILYEMLVGRPPFVAQTALDTQIRVVQWSRHLRIPGEPRLHRDAADLIQRLLCDPEDRLADPQQLKKHNFFAEINWETLPTQKPPYVPVIMDELDTSNFDAVDDDVDKEEPEASQS-----SGNGTFGLSGAPHSFPDFTFKRFFDQDN 997
BLAST of WTS vs. TrEMBL
Match: A0A5K3F8Y2 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 514.998 bits (1325), Expect = 7.990e-164 Identity = 261/474 (55.06%), Postives = 332/474 (70.04%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENR-MEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDP------------SATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFDHGN 2606
++ V+ A Y+RF+E + V R HKER +R +LE EM MGL + MR++L KESNY+RM+R +M++SMF RIK LGVGAFG V LVRKK+N+QLYAMK LKKR+VV RRQ AHV+AERDILAEAD+ WVVKLFFSFQD +LYLVMEYIPGGDMMSLLIKK +FEE L RFY AE+TLALESVH+LGF+HRDIKPDNIL+ +DGHIKLTDFGLCT FRWTH ++Y WDP + +++ ++ + Q P ++ L RR NR+ +SLVGTPNYIAPEIL+R++YN++CDWWSVGVI+YEMLVG+PPF+A +A TQ RVI W+ L IP L +A D+IRR C+P +RL+DP +K+H FF ++DW L +Q PY P I +ELDTSNFD+VE+++ ++S + + F +FTFKRFFD N
Sbjct: 474 VKAVNPAVYRRFIEQKYFSNVGRVHKEREERQARLEAEMALMGLSEASRAHMRKMLQAKESNYMRMQRARMDESMFLRIKRLGVGAFGWVWLVRKKENRQLYAMKILKKRDVVRRRQLAHVQAERDILAEADSHWVVKLFFSFQDTHALYLVMEYIPGGDMMSLLIKKEVFEEPLARFYIAELTLALESVHALGFIHRDIKPDNILINRDGHIKLTDFGLCTSFRWTHSSKY---WDPVFAIPQPGQEKTTPEGEEALTKPTDDPERAELGDQAWPMHDQTLERRIRSSSNRRCAKSLVGTPNYIAPEILRRQEYNRACDWWSVGVILYEMLVGRPPFVAQTALDTQLRVIQWQRHLRIPGEPRLAADAADLIRRLLCDPEDRLADPWLMKKHAFFAAVDWDKLPSQTPPYVPTILNELDTSNFDAVEEEVSGDDQTSSQI-----SGGGTFGLTSAPHAFPDFTFKRFFDQEN 939
BLAST of WTS vs. TrEMBL
Match: K9UQX7 (Wts protein OS=Macrostomum lignano OX=282301 PE=2 SV=1) HSP 1 Score: 498.049 bits (1281), Expect = 8.462e-164 Identity = 259/463 (55.94%), Postives = 320/463 (69.11%), Query Frame = 3
Query: 1221 NIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFIS---IDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNN-NTDIPFFNFTFKRFFD 2597
IR V AAA K ++E+ E + + H ER R Q+LE EM+K+ L +EQ+RQLL KES +LRMKR K+N MF + LLGVGAFGEV LVRKKDN QLYAMK L+K V R Q AHV AERDIL EADN+W+VKL++SFQD+ +LY VMEYIPGGD+MSLLIKKGIFEE+L RFY AEMTLA+ESVH +GF HRDIKPDN+LL +GHIKLTDFGLCTGFRW+H + Y+ + G E D +N +KPL + + ++R+ +SLVGTPNYIAPEIL+R Y KSCDWWS+GVI +EM+VG PPFLA S A TQ++VINW FL++P A L A DII R C +P RLSDP+ IK HPFF + ++W L++ APY P IRDELDTSNFD VE D+ + D + TS+ + N F +FT++RFFD
Sbjct: 35 TIRHVPAAACKFYLEHHFENLMKHHHERIKRRQKLEEEMNKVKLSEQAQEQLRQLLSMKESRHLRMKRSKLNVGMFHKHALLGVGAFGEVHLVRKKDNDQLYAMKTLRKSQVALRNQAAHVNAERDILGEADNEWIVKLYYSFQDEKNLYFVMEYIPGGDLMSLLIKKGIFEENLSRFYMAEMTLAIESVHRMGFCHRDIKPDNVLLCSNGHIKLTDFGLCTGFRWSHNSTYW----------------NGGIPEDSVD-MSNDYTSKPL--ERRKRRHRRHCQSLVGTPNYIAPEILQRRHYTKSCDWWSLGVIAFEMMVGHPPFLARSPAETQHKVINWRQFLHVPPAARLRQEASDIIYRLCADPGERLSDPANIKAHPFFCTPDPVNWDTLLHSTAPYVPLIRDELDTSNFDPVE------EDARGADSDGDDTSEQLAQDGINPHEKFPDFTYRRFFD 472
BLAST of WTS vs. TrEMBL
Match: A0A068YB09 (Serine:threonine protein kinase LATS2 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000700100 PE=4 SV=1) HSP 1 Score: 516.538 bits (1329), Expect = 1.483e-163 Identity = 271/486 (55.76%), Postives = 332/486 (68.31%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENR-MEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDP-----------------------SATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSV-EXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFDHGN 2606
++ V+ A Y+RF+E + V R HKER +R +LE EM MGL + MR++L KESNY+RM+R +M++SMF RIK LGVGAFG V LVRKK+N+QLYAMK LKKR+VV RRQ AHV+AERDILAEAD+DWVVKLFFSFQD +LYLVMEYIPGGDMMSLLIKK IFEE L RFY AE+TLAL SVH LGF+HRDIKPDNIL+ +DGHIKLTDFGLCT FRWTH ++Y WDP +A ++ D+EG + V D Q P ++ L RR NR+ +SLVGTPNYIAPEIL+R++YN++CDWWSVGVI+YEMLVG+PPF+A +A TQ RVI W+ L IP L +A D+IR+ C+P +RL+DP +KQH FF S+DW L Q PY P I +ELDTSNFD+V E+ G S+ S + F +FTFKRFFD N
Sbjct: 520 VKAVNPAVYRRFIEQKYFSNVGRVHKEREERQARLEAEMALMGLSEASRAHMRKMLQAKESNYMRMQRARMDESMFIRIKRLGVGAFGWVWLVRKKENRQLYAMKILKKRDVVRRRQLAHVQAERDILAEADSDWVVKLFFSFQDSHALYLVMEYIPGGDMMSLLIKKEIFEEPLARFYTAELTLALGSVHELGFIHRDIKPDNILINRDGHIKLTDFGLCTSFRWTHSSKY---WDPVFAIPQPGHEKTTTIPTTTEAVATAGTTGLAEGDTEGDEGEVGD-QVWPMHDQTLERRIRSSSNRRCAKSLVGTPNYIAPEILRRQEYNRACDWWSVGVILYEMLVGRPPFVAQTALDTQLRVIQWQRHLRIPGEPRLASDAADLIRKLLCDPEDRLADPRLMKQHAFFDSVDWDKLPTQTPPYVPTILNELDTSNFDAVDEEAGGDDQASSQSSCGGAGGGGGTFGLTSAPHAFPDFTFKRFFDQDN 1001
BLAST of WTS vs. Ensembl Cavefish
Match: lats2 (large tumor suppressor kinase 2 [Source:NCBI gene;Acc:103025207]) HSP 1 Score: 491.5 bits (1264), Expect = 2.933e-156 Identity = 251/464 (54.09%), Postives = 319/464 (68.75%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDS---EGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSD--PSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
I+ A+K +ME +E + +T++++ +R QLE EM K GL + QMR++L QKESNY R++R KM+KSMF +IK LG+GAFGEV L RK D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ SLY VM+YIPGGDMMSLLI+ G+F E L RFY AE+TLA+ESVH +GF+HRDIKPDNIL+ DGHIKLTDFGLCTGFRWTH ++YY+ + HI QDS F + V++ + L L +R NR R SLVGTPNYIAPE+L R+ Y + CDWWSVGVI++EMLVGQPPFLAP+ TQ +VINWES L +P L P A DII R CC+ RL EIK HPFF +D+ NL Q APY+P I +DTSNFD VE++ + S+S + N + + F+ FTF+RFFD
Sbjct: 631 IKSYSPFAFKFYMEQHVENIMKTYQQKLNRRLQLEQEMSKAGLSEAEQGQMRKMLNQKESNYNRLRRAKMDKSMFVKIKTLGIGAFGEVCLTRKVDTGALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVRLYYSFQDRDSLYFVMDYIPGGDMMSLLIRMGVFPEQLARFYVAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGN-------HIRQDSMEPSDFWDDVSNCRCGDRLIT-LEQRANRQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQIKVINWESTLQVPPQVKLSPEAVDIIGRLCCSAEERLGSNGAGEIKAHPFFSQVDFSSNLRTQPAPYRPKIAHPMDTSNFDPVEEEGSPGAWSDSGDSTRAWDTLCSPNGKHPEHAFYEFTFRRFFD 1086
BLAST of WTS vs. Ensembl Cavefish
Match: lats2 (large tumor suppressor kinase 2 [Source:NCBI gene;Acc:103025207]) HSP 1 Score: 491.5 bits (1264), Expect = 2.933e-156 Identity = 251/464 (54.09%), Postives = 319/464 (68.75%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDS---EGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSD--PSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
I+ A+K +ME +E + +T++++ +R QLE EM K GL + QMR++L QKESNY R++R KM+KSMF +IK LG+GAFGEV L RK D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ SLY VM+YIPGGDMMSLLI+ G+F E L RFY AE+TLA+ESVH +GF+HRDIKPDNIL+ DGHIKLTDFGLCTGFRWTH ++YY+ + HI QDS F + V++ + L L +R NR R SLVGTPNYIAPE+L R+ Y + CDWWSVGVI++EMLVGQPPFLAP+ TQ +VINWES L +P L P A DII R CC+ RL EIK HPFF +D+ NL Q APY+P I +DTSNFD VE++ + S+S + N + + F+ FTF+RFFD
Sbjct: 631 IKSYSPFAFKFYMEQHVENIMKTYQQKLNRRLQLEQEMSKAGLSEAEQGQMRKMLNQKESNYNRLRRAKMDKSMFVKIKTLGIGAFGEVCLTRKVDTGALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVRLYYSFQDRDSLYFVMDYIPGGDMMSLLIRMGVFPEQLARFYVAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGN-------HIRQDSMEPSDFWDDVSNCRCGDRLIT-LEQRANRQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQIKVINWESTLQVPPQVKLSPEAVDIIGRLCCSAEERLGSNGAGEIKAHPFFSQVDFSSNLRTQPAPYRPKIAHPMDTSNFDPVEEEGSPGAWSDSGDSTRAWDTLCSPNGKHPEHAFYEFTFRRFFD 1086
BLAST of WTS vs. Ensembl Cavefish
Match: lats1 (large tumor suppressor kinase 1 [Source:NCBI gene;Acc:103046698]) HSP 1 Score: 490.345 bits (1261), Expect = 3.507e-156 Identity = 276/562 (49.11%), Postives = 351/562 (62.46%), Query Frame = 3
Query: 981 LPSVQNPPPIPPKPTRSLSHANPPTLPP---------RQPITTTTETNDCADCIKPNSEDIENETKSSVLVSPDDNSAVP-------EHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQT--NPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDWKNLINQD---APYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
+PS Q PPP PK L PP P ++ +T++ + C +E E + + S VP E + DG + + A+K +ME +E + + H++R R +QLE EM ++GL + +EQMR +L QKESNY+R+KR KM KSMFE+IK LG+GAFGEV L RK D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVVKL++SFQD+ +LY VM+YIPGGDMMSLLI+ GIF E+L +FY AE+T A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H+ QDS F + D D KPL RR R R SLVGTPNYIAPE+L R Y + CDWWSVGVI+YEMLVGQPPFLA + TQ +VINW++ L+IP A L P A D+I + C P +RL EIK HPFF +ID+ + Q APY P I DTSNFD V+ D S D + D N K N + + F+ FTF+RFFD
Sbjct: 519 VPSYQGPPPPYPK---HLQKQQPPAPCPAYEPNPNGRKEDKGGEDDTDNASTCSSERAESSEAAVGTEREKKLINTSPVPVRRNKRDEERRGDGRVQL--YSPQAFKFYMEQHVENILKNHQQRIRRKKQLESEMQRVGLSEDAQEQMRMMLSQKESNYIRLKRAKMEKSMFEKIKTLGIGAFGEVCLARKVDTGALYAMKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDNLYFVMDYIPGGDMMSLLIRLGIFGEELAQFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HVRQDSMDFSKEWEDPANCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILYEMLVGQPPFLATTPLETQMKVINWQTTLHIPPQAKLSPEASDLIVKLCRGPDDRLGKNGADEIKAHPFFKNIDFSIDLRQQQHPAPYIPKITHCTDTSNFDPVDPDKLWSDDDGNHNDTLNGWFK---NGKHPEHAFYEFTFRRFFD 1065
BLAST of WTS vs. Ensembl Cavefish
Match: stk38a (serine/threonine-protein kinase 38 [Source:NCBI gene;Acc:103023219]) HSP 1 Score: 361.688 bits (927), Expect = 1.008e-114 Identity = 190/453 (41.94%), Postives = 270/453 (59.60%), Query Frame = 3
Query: 1260 MENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRL--SDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNT-------DIPFFNFTFKRF 2591
+EN + H+ER R Q+LE MD+ GL K R +KE+ +LR+KR ++ FE +K++G GAFGEV LV+KKD +YAMK L+K +++E+ Q H+RAERDIL EAD+ WVVK+F+SFQD+ +LYL+ME++PGGDMM+LL+KK E+ +FY AE LA++S+H LGF+HRDIKPDN+LL GH+KL+DFGLCTG + H ++Y++ + S S + T ++N + R+ S VGTP+YIAPE+ + YNK CDWWS+GVI+YEML+G PPF + + T +V+NW L P + A+D+I RFCC R+ + EIK + FF +D+ ++ + A I+ DTSNFD D PTSKS + +N++ D F N+T+KRF
Sbjct: 27 LENFYSNLISQHEEREMRQQKLEKVMDQEGLADEEKRMRRSQHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKMNLYLIMEFLPGGDMMTLLMKKDTLTEEATQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDF-----------------TFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQNGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWRETLTFPPEVPISEKAKDLILRFCCESDVRIGATGVEEIKSNAFFEGVDYDHIRERPAAIPIEIKSIDDTSNFDEF-----------PESDILQPTSKSTVVSNHSEADLKSKDWVFINYTYKRF 451
BLAST of WTS vs. Ensembl Cavefish
Match: stk38l (serine/threonine kinase 38 like [Source:ZFIN;Acc:ZDB-GENE-040426-798]) HSP 1 Score: 358.992 bits (920), Expect = 7.236e-114 Identity = 192/446 (43.05%), Postives = 274/446 (61.43%), Query Frame = 3
Query: 1260 MENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPS--EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRF 2591
+EN + H+ER R ++LE MD+ GL E++R +KE+ +LR+KR ++ FE +K++G GAFGEV LV+KKD +YAMK L+K +++E+ Q AH+RAERDIL EAD WVVK+F+SFQD+ +LYL+ME++PGGDMM+LL+KK E+ +FY AE LA++S+H LGF+HRDIKPDN+LL GH+KL+DFGLCTG + H ++Y++ + S + FQ ++N + R+ S VGTP+YIAPE+ + YNK CDWWS+GVI+YEML+G PPF + + T +V+NW+ L P + A+D+I R+C + NR+ S EIK HPFF S+DW+++ + A I+ DTSNFD +S+ Q N T S+ D F N+T+KRF
Sbjct: 28 LENFYSTLLTQHEEREMRQKKLEKVMDEEGL---LDEEVRHA--RKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLSEEATQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSRGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDF-------SFQ----------NMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLIFPPEVPISEKAKDLILRYCTDAENRIGAVSVEEIKSHPFFESVDWEHIRERPAAISIEIKSIDDTSNFDDF-------PESDILQPVTNVTEPSK------DWVFLNYTYKRF 438
BLAST of WTS vs. Ensembl Sea Lamprey
Match: stk38l (serine/threonine kinase 38 like [Source:ZFIN;Acc:ZDB-GENE-040426-798]) HSP 1 Score: 305.064 bits (780), Expect = 1.981e-95 Identity = 159/374 (42.51%), Postives = 224/374 (59.89%), Query Frame = 3
Query: 1488 VALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSL----VGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRF 2591
V LV+KKD +YAMK L+K +++E+ Q AH+RAERDIL EADN WVVK+F+SFQD +LYL+ME++PGGDMM+LL+KK E+ +FY AE LA++S+H LGF+HRDIKPDN+LL GH+KL+DFGLCTG + H ++Y+ + S + S +KP+ ++ +K R L VGTP+YIAPE+ + YNK CDWWS+GVI++EML+G PPF + S T +V++W L P + + D+I RFCC NR+ EIK H FF +DW+++ + A I+ DTSNFD + + ++ + SK + D F N+T+KRF
Sbjct: 1 VRLVQKKDTGHIYAMKVLRKADMLEKEQVAHIRAERDILVEADNLWVVKMFYSFQDPKNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAESILAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRDLTQAQPSDFSTS-------------------SKPMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFLQTGYNKLCDWWSLGVIMFEMLIGYPPFCSESPQETYRKVMHWRETLVFPPEVPISEKSRDLILRFCCEAENRVGANGVEEIKTHAFFEGVDWEHMRERPAAIPIEIKSIDDTSNFDEF-PESDLLQTTGGNEQTTDAESKYK------DWVFINYTYKRF 348
BLAST of WTS vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002084.1 (pep scaffold:Pmarinus_7.0:GL476486:6827:40506:-1 gene:ENSPMAG00000001890.1 transcript:ENSPMAT00000002084.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 261.151 bits (666), Expect = 7.824e-76 Identity = 136/361 (37.67%), Postives = 200/361 (55.40%), Query Frame = 3
Query: 1413 RMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFE----EDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILK-----REKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHA-NLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFD 2459
R+K ++++ FE +K++G GAFGEVA+V+ K +++++AMK L K +++R +TA R ERD+L D+ W+ L ++FQD+ LYLVM+Y GGD+++LL K FE E++ +FY AEM LA+ S+H L +VHRDIKPDN+LL +GHI+L DFG C +++ DG + VGTP+YI+PEIL+ + KY CDWWS+GV +YEML G+ PF A S T +++N + P ++ + + +D+IR C+ R + K HPFF IDW N+ N +APY P + DTSNFD
Sbjct: 7 RVKEMRLHREDFEMLKVIGRGAFGEVAVVKLKSSEKVFAMKILNKWEMLKRAETACFREERDVLVRGDSQWITTLHYAFQDENYLYLVMDYYVGGDLLTLLSK---FEDRLPEEMAKFYVAEMVLAIHSIHELKYVHRDIKPDNVLLDMNGHIRLADFGSCL--------------------------------KLLTDGTVQSSV-------------------AVGTPDYISPEILQAMEDGKGKYGPECDWWSLGVCMYEMLFGETPFYAESLVETYGKIMNHKERFQFPTNSVEVSDDGKDLIRHLICSREQRFGRNGIQDFKNHPFFAGIDWDNIRNCEAPYIPEVSSPTDTSNFD 313
BLAST of WTS vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003561.1 (pep scaffold:Pmarinus_7.0:GL478057:5187:43749:1 gene:ENSPMAG00000003167.1 transcript:ENSPMAT00000003561.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 258.455 bits (659), Expect = 1.229e-71 Identity = 146/393 (37.15%), Postives = 217/393 (55.22%), Query Frame = 3
Query: 1428 KMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREK----YNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISID--WKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTF 2582
+M + ++ +K++G GAFGEV LVR K K++YAMK L K + +R +A ERDI+A A++ WVV+LF++FQD LY+VMEY+PGGD+++L+ + E+ RFY AE+ LAL+++HS+GF+HRD+KPDN+LL K+GH+KL DFG C + D+EG + D + VGTP+YI+PE+LK + Y + CDWWSVGV +YEMLVG PF A S T ++++ ++ LN P ++ +A+++I F + R+ EIK+HPFF + W+N+ AP P + + DTSNFD +E+D P K+ N +PF FT+
Sbjct: 70 RMRANDYDVVKVIGRGAFGEVQLVRHKATKKVYAMKLLSKFEMTKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDHRYLYMVMEYMPGGDLVNLMSNYDVPEK-WARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKNGHLKLADFGTC------------------------MKMDTEGM--VRCD-------------------------TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNALNFPDDVDISKDAKNLICAFLIDREVRVGRNGVGEIKRHPFFKNDQWTWENIRETAAPVVPELVSDTDTSNFDEIEEDKAEDETF--------PVPKAFSGNQ---LPFVGFTY 399
BLAST of WTS vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004595.1 (pep scaffold:Pmarinus_7.0:GL477044:11103:63873:-1 gene:ENSPMAG00000004137.1 transcript:ENSPMAT00000004595.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 249.21 bits (635), Expect = 1.578e-68 Identity = 143/399 (35.84%), Postives = 212/399 (53.13%), Query Frame = 3
Query: 1428 KMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREK----YNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDP--SEIKQHPFFISID--WKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFDH 2600
+M ++ +K++G GAFGEV LVR K K +YAMK L K +++R +A ERDI+A A++ W+V+LF+SFQD LY+VMEY+PGGD+++L+ + E RFY AE+ LA++++HS+G++HRD+KPDN+LL K GH+KL DFG C ++ DG D + VGTP+YI+PE+L+ + Y + CDWWSVGV ++EMLVG PF A S T ++++ + L P ++ NA+ +I F RL +EIK H FF + W+N+ AP P + + DTSNFD +E+D + P K+ + N +PF FT+ + DH
Sbjct: 41 RMRADDYDSVKVIGRGAFGEVQLVRHKVTKSVYAMKLLNKLEMIKRSDSAFFWEERDIMAFANSPWIVQLFYSFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLAVDAIHSMGYIHRDVKPDNMLLDKSGHLKLADFGTCM--------------------------------KLNKDGMVRCD-------------------TAVGTPDYISPEVLRSQGGQGYYGRECDWWSVGVFLFEMLVGDTPFYAESLVGTYGKIMDHKKSLTFPVDLDISKNAKSLICAFLTERDVRLGKNGFAEIKCHDFFKNDQWTWENIRETSAPVVPELSSDTDTSNFDEIENDKSADETF--------PQPKAFVGNQ---LPFVGFTY--YKDH 374
BLAST of WTS vs. Ensembl Sea Lamprey
Match: mast2 (microtubule associated serine/threonine kinase 2 [Source:ZFIN;Acc:ZDB-GENE-050309-150]) HSP 1 Score: 231.106 bits (588), Expect = 6.305e-63 Identity = 133/352 (37.78%), Postives = 188/352 (53.41%), Query Frame = 3
Query: 1416 MKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFC-CNPANRLSDPS--EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDS 2462
+ ++K + FE IKL+ GA+G V LVR K+ +Q +AMKK+ K+N++ R Q ERDIL A+N +VV +F SF+ + L +VMEY+ GGD +LL G D+ + Y AE LALE +H+ G VHRD+KPDN+L+T GH+KLTDFGL + Y+ HI +D+ F + + + GTP YIAPE++ R+ Y K DWW++GVI+YE LVG PF + +VI+ E + L + +D+I NP RL E+KQH FF S+DW L+ Q A + P + E DTS FD+
Sbjct: 204 LPKKKPCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNLYEE---------HIEKDTREFLD----------------------------KQVCGTPEYIAPEVILRQGYGKPVDWWAMGVILYEFLVGCVPFFGDTPEELFGQVISDE-IVWPEGEDALPSDVQDLITGLLERNPLERLGTGGAFEVKQHQFFHSLDWDGLLRQKAEFVPQLESEEDTSYFDT 517
BLAST of WTS vs. Ensembl Yeast
Match: CBK1 (Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]) HSP 1 Score: 328.176 bits (840), Expect = 1.040e-99 Identity = 184/466 (39.48%), Postives = 271/466 (58.15%), Query Frame = 3
Query: 1239 AAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHW----------DPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRL---SDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNF--DSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRF 2591
AAA K +EN + + ER +R +LE E+ K + L +KES +LR++R +++ F +K++G GAFGEV LV+KKD ++YAMK L K + ++ Q AHV+AERD+LA +D+ WVV L++SFQD LYL+ME++PGGD+M++LI+ +F ED+ RFY AE LA+E++H LGF+HRDIKPDNIL+ GHIKL+DFGL TGF TH + YYK T + + + + Q +V D + N+ I+ + + S VGTP+YIAPEI + Y + CDWWS+G I+YE L+G PPF + + T +++N+E L P ++ AED+IRR + RL EIK HPFF +DW + +APY P + DT F D +E+ S + + +++ + T + D+PF +T+ RF
Sbjct: 283 AAAVKLKIENFYQSSVKYAIERNERRVELETELTSHNWSEERKSRQLSSLGKKESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAY-STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFIGYTYSRF 747
BLAST of WTS vs. Ensembl Yeast
Match: DBF20 (Ser/Thr kinase involved in late nuclear division; one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; DBF20 has a paralog, DBF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006315]) HSP 1 Score: 225.713 bits (574), Expect = 2.611e-64 Identity = 126/363 (34.71%), Postives = 195/363 (53.72%), Query Frame = 3
Query: 1383 LLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIP----AHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFD 2459
L LQ+E LR +R K F+ + +G G +G+V L +KKD+ ++ A+K L K+ + + +T HV ERDIL +DW+VKL ++FQD SLYL ME++PGGD +LLI I + RFY +EM A+ ++H LG+ HRD+KP+N L+ GHIKLTDFGL G + S I + E A + + + ++ I R + S+VG+P+Y+A E+L+ +KY+ + D+WS+G +++E LVG PF S T + W+ L P A D+I R +P NR+ ++++ +F I+++ L P+ P + DE D FD
Sbjct: 148 LYLQREHEVLRKRRLKPKHKDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIE-----------SMKIRLEEVKNLEFPAFTERSIE-DRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITRLIADPINRVRSFEQVRKMSYFAEINFETLRTSSPPFIPQLDDETDAGYFD 498
BLAST of WTS vs. Ensembl Yeast
Match: DBF2 (Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication [Source:SGD;Acc:S000003324]) HSP 1 Score: 225.328 bits (573), Expect = 4.953e-64 Identity = 128/361 (35.46%), Postives = 192/361 (53.19%), Query Frame = 3
Query: 1389 LQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIP----AHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFD 2459
LQ+E LR +R K FE I +G G +G+V L RKKD K++ A+K L K+ + + +T HV ERDIL ++W+VKL ++FQD SLYL ME++PGGD +LLI + RFY +EM A+ ++H LG+ HRD+KP+N L+ GHIKLTDFGL G S I + E A + + + ++ + + R K + S+VG+P+Y+A E+L+ +KY+ + D+WS+G +++E LVG PF S T + W+ L P A D+I R +P NRL +K+ +F I++ L + P+ P + E D FD
Sbjct: 158 LQREHQVLRKRRLKPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAG-----------TISNERIESMKIRLEKIKDLEFPAFTEKSIE-DRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITRLIADPINRLRSFEHVKRMSYFADINFSTLRSMIPPFTPQLDSETDAGYFD 506
BLAST of WTS vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 208.764 bits (530), Expect = 5.761e-60 Identity = 127/373 (34.05%), Postives = 196/373 (52.55%), Query Frame = 3
Query: 1365 KEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCC-NPANRLSD----PSEIKQHPFFISIDWKNLI--NQDAPYKPYI-RDELDTSNFD 2459
+EQ +Q + Q R+ K + F+ ++ LG G+FG V L+R + N + YAMK LKK VV +Q H ER +L+ + ++++++ +FQD ++++M+YI GG++ SLL K F + +FYAAE+ LALE +HS ++RD+KP+NILL K+GHIK+TDFG A+Y PD+ L GTP+YIAPE++ + YNKS DWWS G+++YEML G PF + T +++N E L P N D +D++ R + + RL + ++K HP+F + W+ L+ N + PY+P I + + DTS FD
Sbjct: 65 EEQYKQFIAQA-----RVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGF---------AKYV------------------------------PDVTYTL----------------CGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAE--LRFPPFFNED--VKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFD 373
BLAST of WTS vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 207.608 bits (527), Expect = 1.273e-59 Identity = 124/366 (33.88%), Postives = 194/366 (53.01%), Query Frame = 3
Query: 1386 LLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCC-NPANRLSD----PSEIKQHPFFISIDWKNLINQ--DAPYKPYI-RDELDTSNFD 2459
L++K R K + S F+ ++ LG G+FG V L+R N + YA+K LKK +V+ +Q H ER +L+ + ++++++ +FQD +++VM+YI GG++ SLL K F + +FYAAE+ LALE +HS ++RD+KP+NILL K+GHIK+TDFG A+Y PD+ L GTP+YIAPE++ + YNKS DWWS GV++YEML G PF + T ++N E L P P+A+D++++ + + RL + ++K HP+F + W+ L+ + + PY+P I + + DTS FD
Sbjct: 68 LVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGF---------AKYV------------------------------PDVTYTL----------------CGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAE--LKFPPF--FHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFD 374
BLAST of WTS vs. Ensembl Nematostella
Match: EDO36034 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJR1]) HSP 1 Score: 448.358 bits (1152), Expect = 4.147e-149 Identity = 230/394 (58.38%), Postives = 277/394 (70.30%), Query Frame = 3
Query: 1335 MDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDS-----EGFQEIVADGQTNPDLN--------KPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSD--PSEIKQHPFFISIDWKNLINQ-DAPYKPYIRDELDTSNFDSVE 2468
M K+GL + QMRQLL QKE+NY+R+KR KM+ SMFE+I+ +G+GAFGEV LVRK D LYAMK L+K V R Q AHV+AERDILAEADN+WVVKL++SFQDQ +LY VM+Y+PGGD+MSLLIK GIF ED +FY AE+ LA++SVH +GFVHRDIKPDNIL+ KDGHIKLTDFGLCTGFRWTH ++YY+ H+ QDS ++E+ A D++ KPL RR R R SLVGTPNYIAPE+L R Y +SCDWWSVGVI+YEMLVGQPPFLAP+ A TQ ++INWE+ L IP A L A+D+I R C N RL SEIK HPFF +DW L + APY P IR DT+NFD V+
Sbjct: 1 MRKVGLSEEAQSQMRQLLKQKETNYIRLKRTKMDISMFEKIRTIGIGAFGEVWLVRKTDTSMLYAMKILRKSEVFRRNQAAHVKAERDILAEADNEWVVKLYYSFQDQENLYFVMDYVPGGDLMSLLIKFGIFPEDYAKFYIAELVLAIDSVHRMGFVHRDIKPDNILIDKDGHIKLTDFGLCTGFRWTHDSKYYE-------KGQHMRQDSMEPDERAWEEMRATCHCG-DISIDKPYSEMKPLERRHFRKHMRCQAHSLVGTPNYIAPEVLLRIGYRQSCDWWSVGVILYEMLVGQPPFLAPTPAETQLKIINWETELRIPHQARLSREAKDLILRLCTNADMRLGSNGASEIKAHPFFACVDWAYLAKRVQAPYTPVIRFPTDTANFDPVD 386
BLAST of WTS vs. Ensembl Nematostella
Match: EDO42700 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0M7]) HSP 1 Score: 364.385 bits (934), Expect = 2.112e-116 Identity = 193/440 (43.86%), Postives = 269/440 (61.14%), Query Frame = 3
Query: 1293 HKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSL----VGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSR---LNNNNTDIPFFNFTFKRF 2591
H ER +R++ LE M + GL KE+ R+L QKE+ +LR+KR ++ K F+ +K++G GAFGEV LV+K+D +YAMK L+K +++E+ Q AH RAERDILAEA+N WVVK+++SFQD L+LVME++PGGD+M+LL+KK F E+ RFY AE LA++S+H LGF+HRDIKPDN+LL GHIKL DFGLCTG + H ++Y+ P+ + +N D PL ++ ++ R L VGTP+YIAPE+ ++ Y KSCD+WS+GVI+YEML+G PPF + S T +V+NW L P + PNA D+I R RLS+ +I+ PFF +DW+NL ++ A ++ DTSNFD + TSKS L ++ D F N+TFKRF
Sbjct: 43 HYERKNRLKLLEQSMTQQGLSEAEKEERRKLHAQKETEFLRLKRSRIGKEDFDSLKVIGRGAFGEVRLVQKQDTGHVYAMKILRKADMLEKEQVAHARAERDILAEAENQWVVKMYYSFQDDYYLFLVMEFLPGGDLMTLLMKKDTFTEEETRFYIAEALLAIDSIHQLGFIHRDIKPDNLLLDSRGHIKLADFGLCTGLKKAHRTEFYRDISPADIKDF-----------------SNGD---PLDSKRRAATWKRNRRQLAYSTVGTPDYIAPEVFIQQGYTKSCDFWSLGVIMYEMLIGYPPFCSESPQETYKKVMNWRETLVFPPEMPISPNARDLISR------QRLSNIEDIRAQPFFKYVDWENLRDRPAALPIQVKSIDDTSNFDEFPETDLD-------------TSKSNSLLLCTHSKDWVFLNYTFKRF 443
BLAST of WTS vs. Ensembl Nematostella
Match: EDO37677 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SF23]) HSP 1 Score: 241.506 bits (615), Expect = 4.566e-71 Identity = 135/357 (37.82%), Postives = 189/357 (52.94%), Query Frame = 3
Query: 1416 MKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIK-KGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKR-----EKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVE 2468
++R ++K+ F + +G G FGEV +V+ K +YAMK LKK + A ER+I+A A+N W+ L ++FQD SLYLVM+Y PGGD++SLL K IFEED+ RFY AE+ +A+ S+H++GFVHRD+KPDN+L+ + GHIKL DFG SS +S D + F ++ VGTP YIAPE+L Y CDWWS+GV+ YEML GQ PF A S T +++N++S L P+ + +A+++I + R+ + H FF I+W L N PY P + DTSNFD E
Sbjct: 72 LRRLSLSKNDFNVVNTIGRGHFGEVQVVKDKATGDVYAMKTLKKSQTLSEEAVAFFEEEREIMATANNPWITSLQYAFQDSHSLYLVMDYHPGGDLLSLLSKYDDIFEEDMARFYLAEIVMAIHSLHTMGFVHRDVKPDNVLIDRTGHIKLADFG----------------------SSARLSADKKVFSKMP-----------------------------VGTPEYIAPEVLTSMDGSGGAYGVECDWWSLGVVAYEMLFGQTPFEADSVVVTYSKIMNFKSSLRFPSEPKISEDAKELIHNLLTSSEGRIGYEG-LGCHKFFNGIEWNKLQNTLPPYVPTLDGTDDTSNFDEFE 376
BLAST of WTS vs. Ensembl Nematostella
Match: EDO42523 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S134]) HSP 1 Score: 224.942 bits (572), Expect = 5.360e-63 Identity = 132/346 (38.15%), Postives = 183/346 (52.89%), Query Frame = 3
Query: 1446 FERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSA----AHTQYRVINWESFLNIPAHANLDPNAEDIIRRFC-CNPANRLSDPS--EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDS 2462
F+ IKL+ GAFG V LVR K+ +A+KK+ K ++ + Q V AERDIL A+N +VV L+ F+ + L +VMEY+ GGD SLL G DL R Y AE LA+E +HS G VHRDIKPDN+L+T GHIKLTDFGL + Y+H + +D++ F + + + GTP+Y+APE++ R+ Y ++ DWWS+G+I+YE L+G PPF + AHT I + P +A D+IR +P RL E+K+H FF +DW L+ Q A + P + E DTS FDS
Sbjct: 288 FDYIKLISNGAFGAVYLVRHKETHTRFAIKKINKHAMLHKNQVEQVFAERDILTFAENPFVVGLWCCFETKKHLCMVMEYVEGGDCASLLKNIGALPADLARMYFAETVLAVEYLHSYGIVHRDIKPDNLLITSLGHIKLTDFGLSKIGLMNSTTRMYEH---------SLDRDTKQFMD----------------------------KQVFGTPDYLAPEVILRQGYGRAVDWWSMGIILYEFLMGVPPFYGDTPEELFAHTLSGDIEGLDGEDAPPD-----DAVDLIRGLLEQDPTQRLGSAGALEVKEHVFFTGLDWTALLRQKAEFIPQLEGEDDTSYFDS 591
BLAST of WTS vs. Ensembl Nematostella
Match: EDO32008 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW88]) HSP 1 Score: 203.371 bits (516), Expect = 4.049e-59 Identity = 105/273 (38.46%), Postives = 155/273 (56.78%), Query Frame = 3
Query: 1416 MKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREK----YNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHT 2222
++ ++N F+ +K++G GAFGEV LVR K++YAMK L K +++R +A ER+I+A ++++W+VKL ++FQD+ LY+VM+Y+ GGD+++L+ I E +FY AE+ LAL+++H++GFVHRD+KPDN+LL +GH+KL DFG C + DG D + VGTP+YI+PE+LK + Y + CDWWSVGV +YEMLVG PF A S T
Sbjct: 57 IQTHRLNNDDFKTLKVIGRGAFGEVQLVRHTHTKKVYAMKLLSKFEMIKRSDSAFFWEEREIMAHSNSNWIVKLHYAFQDEKYLYMVMDYMSGGDLVNLMSNYEI-PEKWAKFYCAEVVLALDAIHTMGFVHRDVKPDNMLLDGEGHLKLADFGTC--------------------------------MRMDRDGMVRSD-------------------TAVGTPDYISPEVLKSQGGEGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGT 277
BLAST of WTS vs. Ensembl Medaka
Match: lats1 (large tumor suppressor kinase 1 [Source:NCBI gene;Acc:101157749]) HSP 1 Score: 488.804 bits (1257), Expect = 4.291e-156 Identity = 254/458 (55.46%), Postives = 324/458 (70.74%), Query Frame = 3
Query: 1245 AYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQ---EIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRL-NNNNTDIPFFNFTFKRFFD 2597
A+K FME +E + + H++R R +QLE EM ++GL S +EQMR +L QKESNY+R+KR KM KSMF++IK LG+GAFG+V L RK+D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ +LY VMEYIPGGDMMSLLI+ GIF+EDL +FY AE+T A+ESVH +GF+HRDIKPDNIL+ +DGHIKLTDFGLCTGFRWTH ++YY+ D H+ QDS F E A+ + + D KPL RRK R R SLVGTPNYIAPE+L R Y + CDWWSVGVI+YEM+VGQPPF A + TQ +VINW++ L+IP A L P A D+I + C +P +RL EIK H FF +ID+ +L Q APY P I +DTSNFD V+ S S+++ N T S N + + F+ FTF+RFFD
Sbjct: 584 AFKFFMEQHVENILKNHQQRIRRRKQLESEMQRVGLSSEAQEQMRMMLCQKESNYIRLKRAKMEKSMFKQIKTLGIGAFGQVCLARKEDTGSLYAMKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMEYIPGGDMMSLLIRLGIFKEDLAQFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD-------HVRQDSMDFSKEWEESANCRCS-DRLKPLERRKAREHQRCLAHSLVGTPNYIAPEVLLRSGYTQLCDWWSVGVILYEMVVGQPPFFANTPLETQKKVINWKTTLHIPPQAKLSPEASDLIVKLCRDPKDRLGTNGADEIKAHSFFRTIDFSSDLRQQVAPYIPTIAHSMDTSNFDPVD---PDKLRSMDSENNHNDTLTSLFRNGKHPEHAFYEFTFRRFFD 1030
BLAST of WTS vs. Ensembl Medaka
Match: lats2 (large tumor suppressor kinase 2 [Source:NCBI gene;Acc:101165431]) HSP 1 Score: 491.115 bits (1263), Expect = 5.731e-156 Identity = 252/464 (54.31%), Postives = 320/464 (68.97%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDS---EGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
I+ A+K +ME +E V +T++++ +R QLE EM K GL +EQMR++L QKESNY R++R KM+KSMF +IK LG+GAFGEV L RK D LYAMK L+K++V+ R Q AHV+AERDILAEADN+WVV+L++SFQD+ SLY VM+YIPGGDMMSLLI+ G+F E L RFY AE+TLA+ESVH +GF+HRDIKPDNIL+ DGHIKLTDFGLCTGFRWTH ++YY+ H+ QDS F + V++ + L L +R NR R SLVGTPNYIAPE+L R+ Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VINWES L +PA L P A DII R CC +RL EIK HPFF +D+ NL Q APY+P I +DTSNFD VE++ G + S+S + + + + F+ FTF+RFFD
Sbjct: 647 IKSYSPFAFKFYMEQHIENVMKTYQQKLNRRLQLEQEMSKAGLSEAEQEQMRKMLNQKESNYNRLRRAKMDKSMFVKIKTLGIGAFGEVCLTRKVDTGALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVRLYYSFQDRDSLYFVMDYIPGGDMMSLLIRMGVFPEHLARFYVAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQ-------KGSHVRQDSMEPSDFWDDVSNCRCGDRLMT-LEQRANRQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAATPTETQIKVINWESTLQVPAQVKLSPEAVDIIGRLCCAAEDRLGANGAGEIKSHPFFAGVDFSSNLRQQPAPYRPKIAHPMDTSNFDPVEEEGGPGAWSDSGDSTRALDALCFPHGKHPEHAFYEFTFRRFFD 1102
BLAST of WTS vs. Ensembl Medaka
Match: lats2 (large tumor suppressor kinase 2 [Source:NCBI gene;Acc:101165431]) HSP 1 Score: 395.586 bits (1015), Expect = 2.415e-120 Identity = 221/465 (47.53%), Postives = 288/465 (61.94%), Query Frame = 3
Query: 1224 IRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLY-AMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDS---EGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLS--DPSEIKQHPFFISIDW-KNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFD 2597
I+ A+K +ME +E V +T++++ +R QLE EM K ++ RQ + ++ + + K MF R+ +G F L+ Y L K+NV AHV+AERDILAEADN+WVV+L++SFQD+ SLY VM+YIPGGDMMSLLI+ G+F E L RFY AE+TLA+ESVH +GF+HRDIKPDNIL+ DGHIKLTDFGLCTGFRWTH ++YY+ H+ QDS F + V++ + L L +R NR R SLVGTPNYIAPE+L R+ Y + CDWWSVGVI++EMLVGQPPFLA + TQ +VINWES L +PA L P A DII R CC +RL EIK HPFF +D+ NL Q APY+P I +DTSNFD VE++ G + S+S + + + + F+ FTF+RFFD
Sbjct: 647 IKSYSPFAFKFYMEQHIENVMKTYQQKLNRRLQLEQEMSKAVCLLSHVYTARQ-------HAFKLPMKSLCKCMFMRV----LGVFTFKTLILTCSYATFYNHFYHLHKQNV------AHVKAERDILAEADNEWVVRLYYSFQDRDSLYFVMDYIPGGDMMSLLIRMGVFPEHLARFYVAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQ-------KGSHVRQDSMEPSDFWDDVSNCRCGDRLMT-LEQRANRQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAATPTETQIKVINWESTLQVPAQVKLSPEAVDIIGRLCCAAEDRLGANGAGEIKSHPFFAGVDFSSNLRQQPAPYRPKIAHPMDTSNFDPVEEEGGPGAWSDSGDSTRALDALCFPHGKHPEHAFYEFTFRRFFD 1086
BLAST of WTS vs. Ensembl Medaka
Match: stk38a (serine/threonine kinase 38 [Source:NCBI gene;Acc:101163252]) HSP 1 Score: 364.385 bits (934), Expect = 8.767e-116 Identity = 192/447 (42.95%), Postives = 271/447 (60.63%), Query Frame = 3
Query: 1260 MENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPS--EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTS-KSRLNNNNTDIPFFNFTFKRF 2591
+EN + H+ER R Q+LE MD+ GL K R +KE+++LR+KR ++ FE +K++G GAFGEV LV+KKD +YAMK L+K +++E+ Q H+RAERDIL EAD+ WVVK+F+SFQD+ +LYL+ME++PGGDMM+LL+KK E+ +FY AE LA++S+H+LGF+HRDIKPDN+LL GH+KL+DFGLCTG + H +YK+ + S S + QT ++N + R+ S VGTP+YIAPE+ + YNK CDWWS+GVI+YEML+G PPF + + T +V+NW L P + A+D+I RFCC +R+ EIK +PFF +D+ ++ + A I+ DTSNFD DS+ +P S S + N D F N+T+KRF
Sbjct: 27 LENFYSNLIAQHEEREMRQQKLEKVMDQEGLADEEKRIRRSEHARKETDFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKMNLYLIMEFLPGGDMMTLLMKKDTLTEEATQFYIAETVLAIDSIHTLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKAHCTDFYKNLNHSLPSDF--------------SKQTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWRETLTFPPEVPISEKAKDLILRFCCEEEHRIGAAGVLEIKSNPFFEGVDYDHIRERPAAIPINIKSIDDTSNFDEF-------PDSDILTPTASPVSNHSEADLKNKDWVFINYTYKRF 452
BLAST of WTS vs. Ensembl Medaka
Match: stk38l (serine/threonine kinase 38 like [Source:NCBI gene;Acc:101163624]) HSP 1 Score: 361.303 bits (926), Expect = 8.645e-115 Identity = 187/446 (41.93%), Postives = 270/446 (60.54%), Query Frame = 3
Query: 1260 MENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPS--EIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRF 2591
+EN + H+ER R ++LE M++ GL K R +KE+ +LR+KR ++ FE +K++G GAFGEV LV+KKD +YAMK L+K +++E+ Q AH+RAERDIL EAD+ WVVK+F+SFQD+ +LYL+ME++PGGDMM+LL+KK E+ +FY AE LA++S+H LGF+HRDIKPDN+LL GH+KL+DFGLCTG + H ++Y++ + S + FQ ++N + R+ S VGTP+YIAPE+ + YNK CDWWS+GVI+YEML+G PPF + + T +V+NW+ L P + A+D+I R+C + NR+ S EIK H FF S+DW+++ + A I+ DTSNFD D P + + + + D F N+T+KRF
Sbjct: 28 LENFYSTLLTQHEEREMRQKKLEKAMEEEGLPDEEKVMRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADSAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLSEEATQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSRGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDF-------SFQ----------NMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRYCTDAENRVGAGSVDEIKSHQFFESVDWEHIRERPAAISIEIKSIDDTSNFDDF-----------PESDILQPANSTEPDFKSKDWVFLNYTYKRF 445
BLAST of WTS vs. Planmine SMEST
Match: SMESG000057360.1 (SMESG000057360.1) HSP 1 Score: 1581.23 bits (4093), Expect = 0.000e+0 Identity = 837/838 (99.88%), Postives = 837/838 (99.88%), Query Frame = 3
Query: 96 MDHYSNENVSLITKTASFPMYPMSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAXXXXXXXXXXXXXXXXXXXXXXXNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIENETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS 2609
MDHYSNENVSLITKTASFPMYPMSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAPPLPPKLSPQPSLQPSLEELSSSNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIE ETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIRRKNRFKNRKFMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEDDIGSSSDSNSSQDDDNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS
Sbjct: 1 MDHYSNENVSLITKTASFPMYPMSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAPPLPPKLSPQPSLQPSLEELSSSNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIEIETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIRRKNRFKNRKFMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEDDIGSSSDSNSSQDDDNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS 838
BLAST of WTS vs. Planmine SMEST
Match: SMESG000057360.1 (SMESG000057360.1) HSP 1 Score: 1541.55 bits (3990), Expect = 0.000e+0 Identity = 818/819 (99.88%), Postives = 818/819 (99.88%), Query Frame = 3
Query: 153 MYPMSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAXXXXXXXXXXXXXXXXXXXXXXXNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIENETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS 2609
MYPMSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAPPLPPKLSPQPSLQPSLEELSSSNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIE ETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIRRKNRFKNRKFMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEDDIGSSSDSNSSQDDDNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS
Sbjct: 1 MYPMSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAPPLPPKLSPQPSLQPSLEELSSSNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIEIETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIRRKNRFKNRKFMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEDDIGSSSDSNSSQDDDNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS 819
BLAST of WTS vs. Planmine SMEST
Match: SMESG000057360.1 (SMESG000057360.1) HSP 1 Score: 1535.39 bits (3974), Expect = 0.000e+0 Identity = 815/816 (99.88%), Postives = 815/816 (99.88%), Query Frame = 3
Query: 162 MSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAXXXXXXXXXXXXXXXXXXXXXXXNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIENETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEXXXXXXXXXXXXXXXXNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS 2609
MSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAPPLPPKLSPQPSLQPSLEELSSSNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIE ETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIRRKNRFKNRKFMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEDDIGSSSDSNSSQDDDNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS
Sbjct: 1 MSNILKMRPIGQNSLNFSEAFLNKTTGCRLDNNNMCPSFLSNAAIHKRPNYLSPNFHPNEYNHAFTNEVMFNSSPIDSVYSSPAYGMRLFPNNEIYAPPLPPKLSPQPSLQPSLEELSSSNNRRMYNECFPTPSYEPTQIRAQLILSKSAVFQQTARSQWLPKNIQRGQAFAINCDSNQPYGASPGGQQMMVNNRDCNSNNRMRPMDTNNHQIMSENVGELIQSGQSKAFVSVDEMLLKSFACDSSRPLFLTNIYKDPIIFQQMDEHTNRNYILPSVQNPPPIPPKPTRSLSHANPPTLPPRQPITTTTETNDCADCIKPNSEDIEIETKSSVLVSPDDNSAVPEHQSKDGYLNIRKVDAAAYKRFMENRMEQVERTHKERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQKESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIRRKNRFKNRKFMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDPSEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFDSVEDDIGSSSDSNSSQDDDNPTSKSRLNNNNTDIPFFNFTFKRFFDHGNS 816
BLAST of WTS vs. Planmine SMEST
Match: SMESG000015619.1 (SMESG000015619.1) HSP 1 Score: 340.887 bits (873), Expect = 4.288e-107 Identity = 178/393 (45.29%), Postives = 244/393 (62.09%), Query Frame = 3
Query: 1299 ERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQ---KESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDP---SEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFD 2459
ER +R++ LE M L ++Q RQ L Q KES YLR+KR K+N + F+ +K++G GAFGEVALV+KKDN +YAMK L+K N++E+ Q AHVRAERDIL + +N WVVK+F+SFQD LYLVME++PGGD+M+LLIK F E+ +FY +E LA++S+H LGF+HRDIKPDN+LL GHIKL+DFGLCTG + +H ++YK D S + + +++ + +T L S VGTP+YIAPE+ +R Y +CDWWS+GVI++EML+G PPF + S T +VI+W L PA + A +I CC NRL + + FF +IDW+++ + A IR D SNFD
Sbjct: 72 ERKNRLKLLEANMKNENLT---EDQRRQRLAQHTLKESEYLRLKRAKLNFNDFQIVKVIGRGAFGEVALVQKKDNGYIYAMKILRKCNMIEKDQIAHVRAERDILTKVNNPWVVKMFYSFQDSHFLYLVMEFLPGGDLMNLLIKMDTFTEEQTQFYISETILAIDSIHKLGFIHRDIKPDNLLLDSKGHIKLSDFGLCTGLKKSHRTEFYK--DLSKAKPCDFTNSIQSKKKVESWKKTRRKL----------------AYSTVGTPDYIAPEVFQRIGYTNACDWWSLGVIMFEMLIGYPPFCSESPGETYLKVISWRESLIFPAEMPISSQACSVINLLCCEHENRLGSKHGVDDFRSLEFFKNIDWEHIRERPAAIHVKIRSIDDVSNFD 443
BLAST of WTS vs. Planmine SMEST
Match: SMESG000015619.1 (SMESG000015619.1) HSP 1 Score: 340.887 bits (873), Expect = 4.653e-107 Identity = 178/393 (45.29%), Postives = 244/393 (62.09%), Query Frame = 3
Query: 1299 ERYDRMQQLEYEMDKMGLDSNYKEQMRQLLLQ---KESNYLRMKRQKMNKSMFERIKLLGVGAFGEVALVRKKDNKQLYAMKKLKKRNVVERRQTAHVRAERDILAEADNDWVVKLFFSFQDQTSLYLVMEYIPGGDMMSLLIKKGIFEEDLGRFYAAEMTLALESVHSLGFVHRDIKPDNILLTKDGHIKLTDFGLCTGFRWTHMAQYYKHWDPSATSSYHISQDSEGFQEIVADGQTNPDLNKPLIXXXXXXXXXXXMRSLVGTPNYIAPEILKREKYNKSCDWWSVGVIVYEMLVGQPPFLAPSAAHTQYRVINWESFLNIPAHANLDPNAEDIIRRFCCNPANRLSDP---SEIKQHPFFISIDWKNLINQDAPYKPYIRDELDTSNFD 2459
ER +R++ LE M L ++Q RQ L Q KES YLR+KR K+N + F+ +K++G GAFGEVALV+KKDN +YAMK L+K N++E+ Q AHVRAERDIL + +N WVVK+F+SFQD LYLVME++PGGD+M+LLIK F E+ +FY +E LA++S+H LGF+HRDIKPDN+LL GHIKL+DFGLCTG + +H ++YK D S + + +++ + +T L S VGTP+YIAPE+ +R Y +CDWWS+GVI++EML+G PPF + S T +VI+W L PA + A +I CC NRL + + FF +IDW+++ + A IR D SNFD
Sbjct: 76 ERKNRLKLLEANMKNENLT---EDQRRQRLAQHTLKESEYLRLKRAKLNFNDFQIVKVIGRGAFGEVALVQKKDNGYIYAMKILRKCNMIEKDQIAHVRAERDILTKVNNPWVVKMFYSFQDSHFLYLVMEFLPGGDLMNLLIKMDTFTEEQTQFYISETILAIDSIHKLGFIHRDIKPDNLLLDSKGHIKLSDFGLCTGLKKSHRTEFYK--DLSKAKPCDFTNSIQSKKKVESWKKTRRKL----------------AYSTVGTPDYIAPEVFQRIGYTNACDWWSLGVIMFEMLIGYPPFCSESPGETYLKVISWRESLIFPAEMPISSQACSVINLLCCEHENRLGSKHGVDDFRSLEFFKNIDWEHIRERPAAIHVKIRSIDDVSNFD 447 The following BLAST results are available for this feature:
BLAST of WTS vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of WTS vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of WTS vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of WTS vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of WTS vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of WTS vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of WTS vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of WTS vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of WTS vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of WTS vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of WTS vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of WTS vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of WTS vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of WTS vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30007679 ID=SMED30007679|Name=WTS|organism=Schmidtea mediterranea sexual|type=transcript|length=2918bpback to top protein sequence of SMED30007679-orf-1 >SMED30007679-orf-1 ID=SMED30007679-orf-1|Name=SMED30007679-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=839bp MDHYSNENVSLITKTASFPMYPMSNILKMRPIGQNSLNFSEAFLNKTTGCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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