Dystrobrevin
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30007670 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Dystrobrevin vs. Ensembl Human
Match: DTNB (dystrobrevin beta [Source:HGNC Symbol;Acc:HGNC:3058]) HSP 1 Score: 335.88 bits (860), Expect = 4.850e-101 Identity = 209/627 (33.33%), Postives = 331/627 (52.79%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHT----NQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ + + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G +I ++F+Q+L ++L L VFEGP+F Y + + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C C E ++GFRY+CQ+CH+Y LCQ+CFW G G HSN H +KE+ SS KS +++ HA+ KS + C + V Q P P N N + + + T + + +S IPS H ++ + L+H + PS+ D+EHRLIARYA+ L + N P ++ D + K Q++LIA+LE KN+ +Q ++ + ++ A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L ++ +++ R M + +A + T Q L+GV
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYTEHSVRTCFPQQRK-IMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKEH-SSWKSPAKKLSHAISKS--------LGCVPTREPPHP--------VFPEQPEKPLDLAHIVPPRPLTNM--------NDTMVSHMSSGVPTPTKRLQYS--QDIPS--HLADEHALIASYVARLQHCARVLDSPSR------LDEEHRLIARYAARLAAEAG---------------NVTRPPTDLSFNFD--------ANKQQRQLIAELENKNR---EILQEIQRLRLEHEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHCPQDSLSGV 561
BLAST of Dystrobrevin vs. Ensembl Human
Match: DTNB (dystrobrevin beta [Source:HGNC Symbol;Acc:HGNC:3058]) HSP 1 Score: 334.339 bits (856), Expect = 1.156e-100 Identity = 235/761 (30.88%), Postives = 362/761 (47.57%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHT----NQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSLLPSNSGQPLKLHGYGSPMTTHRSLSYTADSNRSVTMGPHSILPQPRFNTLTRHSRTFSADEGLGGFASQPRRTFTSGNRTLESLGVDTTDYYLKQSSDKAKQNNSLSKEMDLRQNLLMAADNVTNAMTGLVRN 2500
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ + + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G +I ++F+Q+L ++L L VFEGP+F Y + + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C C E ++GFRY+CQ+CH+Y LCQ+CFW G G HSN H +KE+ SS KS +++ HA+ KS + C + V Q P P N N + + + T + + +S IPS H ++ + L+H + PS+ D+EHRLIARYA+ L + + P T +S + F+ N K Q++LIA+LE KN+ +Q ++ + ++ A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L K QAA +G +P HG G PM P P +T + T + L G + F G R +LR +LL+AAD++TN M+ LV+
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYTEHSVRTCFPQQRK-IMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKEH-SSWKSPAKKLSHAISKS--------LGCVPTREPPHP--------VFPEQPEKPLDLAHIVPPRPLTNM--------NDTMVSHMSSGVPTPTKRLQYS--QDIPS--HLADEHALIASYVARLQHCARVLDSPSR------LDEEHRLIARYAARLAAEA---GNVTRPPTDLSFN---------------FDAN-----KQQRQLIAELENKNR---EILQEIQRLRLEHEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLL---------------KEEEQKQAAQA-------TGSPHTSP--------------THGGGRPM------------------------PMPVRSTSAGSTPTHCPQDSLSGVGGDVQEAFAQGTRR------------------------------NLRNDLLVAADSITNTMSSLVKE 605
BLAST of Dystrobrevin vs. Ensembl Human
Match: DTNB (dystrobrevin beta [Source:HGNC Symbol;Acc:HGNC:3058]) HSP 1 Score: 333.183 bits (853), Expect = 5.389e-100 Identity = 244/761 (32.06%), Postives = 368/761 (48.36%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHT----NQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSLLPSNSGQPLKLHGYGSPMTTHRSLSYTADSNRSVTMGPHSILPQPRFNTLTRHSRTFSADEGLGGFASQPRRTFTSGNRTLESLGVDTTDYYLKQSSDKAKQNNSLSKEMDLRQNLLMAADNVTNAMTGLVRN 2500
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ + + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G +I ++F+Q+L ++L L VFEGP+F Y + + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C C E ++GFRY+CQ+CH+Y LCQ+CFW G G HSN H +KE+ SS KS +++ HA+ K ++ C + V Q P P N N + + + T + + +S IPS H ++ + L+H + PS+ D+EHRLIARYA+ L + + P T +S + F+ N K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L K QAA +G +P HG G PM P P +T + T + L G + F G R +LR +LL+AAD++TN M+ LV+
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYTEHSVRTCFPQQRK-IMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKEH-SSWKSPAKKLSHAISK--------SLGCVPTREPPHP--------VFPEQPEKPLDLAHIVPPRPLTNM--------NDTMVSHMSSGVPTPTKRLQYS--QDIPS--HLADEHALIASYVARLQHCARVLDSPSR------LDEEHRLIARYAARLAAEAG---NVTRPPTDLSFN---------------FDAN-----KQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLL---------------KEEEQKQAAQA-------TGSPHTSP--------------THGGGRPM------------------------PMPVRSTSAGSTPTHCPQDSLSGVGGDVQEAFAQGTRR------------------------------NLRNDLLVAADSITNTMSSLVKE 605
BLAST of Dystrobrevin vs. Ensembl Human
Match: DTNB (dystrobrevin beta [Source:HGNC Symbol;Acc:HGNC:3058]) HSP 1 Score: 331.643 bits (849), Expect = 7.446e-100 Identity = 212/594 (35.69%), Postives = 322/594 (54.21%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHT----NQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSA 1999
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ + + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G +I ++F+Q+L ++L L VFEGP+F Y + + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C C E ++GFRY+CQ+CH+Y LCQ+CFW G G HSN H +KE+ SS KS +++ HA+ K ++ C + V Q P P N N + + + T + + +S IPS H ++ + L+H + PS+ D+EHRLIARYA+ L + N P ++ D + K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L Q A
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYTEHSVRTCFPQQRK-IMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKEH-SSWKSPAKKLSHAISK--------SLGCVPTREPPH--------PVFPEQPEKPLDLAHIVPPRPLTNM--------NDTMVSHMSSGVPTPTKRLQYS--QDIPS--HLADEHALIASYVARLQHCARVLDSPSR------LDEEHRLIARYAARLAAEAG---------------NVTRPPTDLSFNFD--------ANKQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQA 528
BLAST of Dystrobrevin vs. Ensembl Human
Match: DTNB (dystrobrevin beta [Source:HGNC Symbol;Acc:HGNC:3058]) HSP 1 Score: 287.345 bits (734), Expect = 2.451e-84 Identity = 185/581 (31.84%), Postives = 300/581 (51.64%), Query Frame = 2
Query: 368 VVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHT----NQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
++E+FR GL ++ + + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G +I ++F+Q+L ++L L VFEGP+F Y + + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C C E ++GFRY+CQ+CH+Y LCQ+CFW G G HSN H +KE+ SS KS +++ HA+ KS + C + Q + ++ P P N N + + + T + + +S IPS H ++ + L+H + PS+ D+EHRLIARYA+ L + N P ++ D + K Q++LIA+LE KN+ +Q ++ + ++ A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L ++ +++ R M + +A + T Q L+GV
Sbjct: 1 MIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYTEHSVRTCFPQQRK-IMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKEH-SSWKSPAKKLSHAISKS--------LGCVPTREPPHPVFPEQPEKPLDLAHIV--------PPRPLTNM--------NDTMVSHMSSGVPTPTKRLQYS--QDIPS--HLADEHALIASYVARLQHCARVLDSPSR------LDEEHRLIARYAARLAAEAG---------------NVTRPPTDLSFNFD--------ANKQQRQLIAELENKNR---EILQEIQRLRLEHEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHCPQDSLSGV 504
BLAST of Dystrobrevin vs. Ensembl Celegans
Match: dyb-1 (Dystrobrevin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y048]) HSP 1 Score: 264.618 bits (675), Expect = 2.891e-76 Identity = 148/438 (33.79%), Postives = 232/438 (52.97%), Query Frame = 2
Query: 239 FKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSR-----IQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTL 1537
++LI+EM+ + FDSIRFA YR ACKLR+IQQ+T++ L+D+ ++E+FR+ GL + + ++ E+++ ++ L+ RL A + ++ SI +L+ +LL +YD TGRL+V ++KVAL+TL +GK +DK +Y F+ + D +G + +F +L +L L VFE P F ++ A + + + + FL+ L+DP P C++WL + HR+A++ NV H V C+ C GFRYKCQRC +Y LCQ CFW G T+ NHSN H++KEY SS KS ++Q H++ KS C+P +TV A G + P + + N+N + V P+ T++ +W +S P + DDEH+LIARYA+ L
Sbjct: 36 MQQLIDEMRLQDFDSIRFATYRAACKLRFIQQKTKVHLVDIWNMIEAFRENGLNALPLHTVIKTSRAELLLTTVFHNLNKRLVASQHVDTDV---SISLLLAFLLGAYDKQNTGRLTVFSIKVALATLCAGKLVDKLRYIFSQIADSNGLMDHIKFTDFLQQILSLTTAVFEAPTFGFSENAVNQCF-HKDEKVSLNVFLDTFLSDPCPPCIMWLPLLHRMASVSNVYHPVVCDACQVRSFTGFRYKCQRCANYQLCQSCFWRGRTSQNHSNEHEMKEY-SSYKSPTKQLVHSIHKSLQ-------------------------------------------CIPATSTVGDANIDIFNAKIGGPVSSKPARPL-----NLN-NIVPATPTTIRRQHAATSSADWPTS--PVLLPGQASHGGVIDDEHKLIARYAAKL 417
BLAST of Dystrobrevin vs. Ensembl Celegans
Match: dyb-1 (Dystrobrevin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y048]) HSP 1 Score: 211.46 bits (537), Expect = 1.332e-58 Identity = 124/395 (31.39%), Postives = 197/395 (49.87%), Query Frame = 2
Query: 368 VVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSR-----IQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTL 1537
++E+FR+ GL + + ++ E+++ ++ L+ RL A + ++ SI +L+ +LL +YD TGRL+V ++KVAL+TL +GK +DK +Y F+ + D +G + +F +L +L L VFE P F ++ A + + + + FL+ L+DP P C++WL + HR+A++ NV H V C+ C GFRYKCQRC +Y LCQ CFW G T+ NHSN H++KEY SS KS ++Q H++ KS C+P +TV A G + P + + N+N + V P+ T++ +W +S P + DDEH+LIARYA+ L
Sbjct: 1 MIEAFRENGLNALPLHTVIKTSRAELLLTTVFHNLNKRLVASQHVDTDV---SISLLLAFLLGAYDKQNTGRLTVFSIKVALATLCAGKLVDKLRYIFSQIADSNGLMDHIKFTDFLQQILSLTTAVFEAPTFGFSENAVNQCF-HKDEKVSLNVFLDTFLSDPCPPCIMWLPLLHRMASVSNVYHPVVCDACQVRSFTGFRYKCQRCANYQLCQSCFWRGRTSQNHSNEHEMKEY-SSYKSPTKQLVHSIHKSLQ-------------------------------------------CIPATSTVGDANIDIFNAKIGGPVSSKPARPL-----NLN-NIVPATPTTIRRQHAATSSADWPTS--PVLLPGQASHGGVIDDEHKLIARYAAKL 339
BLAST of Dystrobrevin vs. Ensembl Celegans
Match: dys-1 (Dystrophin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TW65]) HSP 1 Score: 120.168 bits (300), Expect = 5.295e-27 Identity = 89/298 (29.87%), Postives = 148/298 (49.66%), Query Frame = 2
Query: 272 QFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESF-RQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLH---PNLIPE---SIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDL-----LVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEY--TSSSKSHSRQFGHALR 1123
QF+ ++F AYRTA KLR +Q+R L L+D+ + ++F R GL E +E M+ L LP + LH PN + ++++ + +LL +D S G + V++ K+A+ ++ +K++Y F L++ G + L+DL LV F G N S S F V + I F++ + +P Q ++WL + HRL E+ +H +C C IIG RY+C C + +LCQ+CF++ T +H H ++EY ++S +R F +R
Sbjct: 993 QFNRVKFLAYRTAMKLRALQKRLCLDLVDLTLLEKAFVRLKGLSAEECPG------LEGMVCAL-------LPMYEALHAKYPNQVQSVSLAVDICINFLLNLFDQSRDGIMRVLSFKIAMIVFSNIPLEEKYRYLFKLVSQ-DGHATQKQIALLLYDLIHIPRLVGESAAFGGTNVE-PSVRSCFETVRLAPTISEGAFIDWVKKEP--QSIVWLAVMHRLVISESTKHASKCNVCKMFPIIGIRYRCLTCFNCDLCQNCFFSQRTAKSHRTNHPMQEYCEKTTSSDDARDFAKMIR 1273
BLAST of Dystrobrevin vs. Ensembl Celegans
Match: dys-1 (Dystrophin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TW65]) HSP 1 Score: 120.168 bits (300), Expect = 6.610e-27 Identity = 89/298 (29.87%), Postives = 148/298 (49.66%), Query Frame = 2
Query: 272 QFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESF-RQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLH---PNLIPE---SIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDL-----LVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEY--TSSSKSHSRQFGHALR 1123
QF+ ++F AYRTA KLR +Q+R L L+D+ + ++F R GL E +E M+ L LP + LH PN + ++++ + +LL +D S G + V++ K+A+ ++ +K++Y F L++ G + L+DL LV F G N S S F V + I F++ + +P Q ++WL + HRL E+ +H +C C IIG RY+C C + +LCQ+CF++ T +H H ++EY ++S +R F +R
Sbjct: 1931 QFNRVKFLAYRTAMKLRALQKRLCLDLVDLTLLEKAFVRLKGLSAEECPG------LEGMVCAL-------LPMYEALHAKYPNQVQSVSLAVDICINFLLNLFDQSRDGIMRVLSFKIAMIVFSNIPLEEKYRYLFKLVSQ-DGHATQKQIALLLYDLIHIPRLVGESAAFGGTNVE-PSVRSCFETVRLAPTISEGAFIDWVKKEP--QSIVWLAVMHRLVISESTKHASKCNVCKMFPIIGIRYRCLTCFNCDLCQNCFFSQRTAKSHRTNHPMQEYCEKTTSSDDARDFAKMIR 2211
BLAST of Dystrobrevin vs. Ensembl Celegans
Match: dys-1 (Dystrophin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TW65]) HSP 1 Score: 120.168 bits (300), Expect = 7.185e-27 Identity = 89/298 (29.87%), Postives = 148/298 (49.66%), Query Frame = 2
Query: 272 QFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESF-RQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLH---PNLIPE---SIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDL-----LVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEY--TSSSKSHSRQFGHALR 1123
QF+ ++F AYRTA KLR +Q+R L L+D+ + ++F R GL E +E M+ L LP + LH PN + ++++ + +LL +D S G + V++ K+A+ ++ +K++Y F L++ G + L+DL LV F G N S S F V + I F++ + +P Q ++WL + HRL E+ +H +C C IIG RY+C C + +LCQ+CF++ T +H H ++EY ++S +R F +R
Sbjct: 1920 QFNRVKFLAYRTAMKLRALQKRLCLDLVDLTLLEKAFVRLKGLSAEECPG------LEGMVCAL-------LPMYEALHAKYPNQVQSVSLAVDICINFLLNLFDQSRDGIMRVLSFKIAMIVFSNIPLEEKYRYLFKLVSQ-DGHATQKQIALLLYDLIHIPRLVGESAAFGGTNVE-PSVRSCFETVRLAPTISEGAFIDWVKKEP--QSIVWLAVMHRLVISESTKHASKCNVCKMFPIIGIRYRCLTCFNCDLCQNCFFSQRTAKSHRTNHPMQEYCEKTTSSDDARDFAKMIR 2200
BLAST of Dystrobrevin vs. Ensembl Fly
Match: Dyb (gene:FBgn0033739 transcript:FBtr0087929) HSP 1 Score: 339.732 bits (870), Expect = 7.275e-103 Identity = 219/622 (35.21%), Postives = 323/622 (51.93%), Query Frame = 2
Query: 248 LINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLN----TSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSL 2101
++ +++ + FDSIRFA+YRTA KLRYIQ+ T L L+D+ V+E+FR+ GL +E + ++E +++ LY L+ RLP Q+ + +L+ WLL +Y + +G++ V ++KVAL+T+ SGK +DK +Y F+ ++D +G L+ + ++L ++L L V+E P F Y + I +K + + +F+ ++++PGP CL+WL + HRLA +E + H C CH+E GFRY+CQRCH Y LCQ+CFW G T+ NH N H+VKEY SS KS S+Q GH+LRKS+ TV Q R D ++ + LP N S +G P Q+ F S + S S + +G +++ S + D+EHRLIARYA+ L S L T I DN+ ++Q+ELIA+LE+KNKEI+REI RLR +Q+ A NP L+ ELR LR RK ELE + +LQ+SR +LM+QLE LMR+L S S NS+ S KS M A G+ G +P+S+L
Sbjct: 9 ILQDLRLQTFDSIRFASYRTASKLRYIQKSTNLHLVDIWNVIEAFRENGLNTLEPQSEVSVARLETLVSSLYHNLNKRLPTAQQVP---VDSKAGLLLNWLLAAYTSDNSGKIRVFSIKVALATMCSGKLVDKLRYIFSQISDGAGQLVAWKLGEFLREVLALPAAVYESPTFHYKEGLEEEIFPAENK-VTVNDFMATLMSEPGPSCLVWLPLVHRLATVETIVHPTVCSVCHKENFTGFRYRCQRCHAYQLCQECFWHGKTSLNHQNDHEVKEY-SSYKSPSKQIGHSLRKSFRCVPEKTV-------------QVLPRFPDQPEKTLNLSHIVPPSPLPSHNGFSDPSGLVHGHHGPHPG----LPGQHGLFDRSSTLDSRATGRSLDSASGTAGTTMSRVAAASAN------DEEHRLIARYAARLAQENRAPSNLPDNATPIGTDNS----------------------RAQRELIAQLESKNKEIMREIARLRRQQETEQMA--------------------PENPALINELRALRQRKGELEGHLGALQDSRRQLMEQLEGLMRMLKNQQTASPRSTPNSSPRSGKSPPMPGGA----------GILGTSPMSAL 550
BLAST of Dystrobrevin vs. Ensembl Fly
Match: Dyb (gene:FBgn0033739 transcript:FBtr0087930) HSP 1 Score: 339.732 bits (870), Expect = 9.390e-103 Identity = 219/622 (35.21%), Postives = 323/622 (51.93%), Query Frame = 2
Query: 248 LINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLN----TSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSL 2101
++ +++ + FDSIRFA+YRTA KLRYIQ+ T L L+D+ V+E+FR+ GL +E + ++E +++ LY L+ RLP Q+ + +L+ WLL +Y + +G++ V ++KVAL+T+ SGK +DK +Y F+ ++D +G L+ + ++L ++L L V+E P F Y + I +K + + +F+ ++++PGP CL+WL + HRLA +E + H C CH+E GFRY+CQRCH Y LCQ+CFW G T+ NH N H+VKEY SS KS S+Q GH+LRKS+ TV Q R D ++ + LP N S +G P Q+ F S + S S + +G +++ S + D+EHRLIARYA+ L S L T I DN+ ++Q+ELIA+LE+KNKEI+REI RLR +Q+ A NP L+ ELR LR RK ELE + +LQ+SR +LM+QLE LMR+L S S NS+ S KS M A G+ G +P+S+L
Sbjct: 18 ILQDLRLQTFDSIRFASYRTASKLRYIQKSTNLHLVDIWNVIEAFRENGLNTLEPQSEVSVARLETLVSSLYHNLNKRLPTAQQVP---VDSKAGLLLNWLLAAYTSDNSGKIRVFSIKVALATMCSGKLVDKLRYIFSQISDGAGQLVAWKLGEFLREVLALPAAVYESPTFHYKEGLEEEIFPAENK-VTVNDFMATLMSEPGPSCLVWLPLVHRLATVETIVHPTVCSVCHKENFTGFRYRCQRCHAYQLCQECFWHGKTSLNHQNDHEVKEY-SSYKSPSKQIGHSLRKSFRCVPEKTV-------------QVLPRFPDQPEKTLNLSHIVPPSPLPSHNGFSDPSGLVHGHHGPHPG----LPGQHGLFDRSSTLDSRATGRSLDSASGTAGTTMSRVAAASAN------DEEHRLIARYAARLAQENRAPSNLPDNATPIGTDNS----------------------RAQRELIAQLESKNKEIMREIARLRRQQETEQMA--------------------PENPALINELRALRQRKGELEGHLGALQDSRRQLMEQLEGLMRMLKNQQTASPRSTPNSSPRSGKSPPMPGGA----------GILGTSPMSAL 559
BLAST of Dystrobrevin vs. Ensembl Fly
Match: Dyb (gene:FBgn0033739 transcript:FBtr0100298) HSP 1 Score: 339.732 bits (870), Expect = 1.889e-102 Identity = 219/622 (35.21%), Postives = 323/622 (51.93%), Query Frame = 2
Query: 248 LINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLN----TSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSL 2101
++ +++ + FDSIRFA+YRTA KLRYIQ+ T L L+D+ V+E+FR+ GL +E + ++E +++ LY L+ RLP Q+ + +L+ WLL +Y + +G++ V ++KVAL+T+ SGK +DK +Y F+ ++D +G L+ + ++L ++L L V+E P F Y + I +K + + +F+ ++++PGP CL+WL + HRLA +E + H C CH+E GFRY+CQRCH Y LCQ+CFW G T+ NH N H+VKEY SS KS S+Q GH+LRKS+ TV Q R D ++ + LP N S +G P Q+ F S + S S + +G +++ S + D+EHRLIARYA+ L S L T I DN+ ++Q+ELIA+LE+KNKEI+REI RLR +Q+ A NP L+ ELR LR RK ELE + +LQ+SR +LM+QLE LMR+L S S NS+ S KS M A G+ G +P+S+L
Sbjct: 9 ILQDLRLQTFDSIRFASYRTASKLRYIQKSTNLHLVDIWNVIEAFRENGLNTLEPQSEVSVARLETLVSSLYHNLNKRLPTAQQVP---VDSKAGLLLNWLLAAYTSDNSGKIRVFSIKVALATMCSGKLVDKLRYIFSQISDGAGQLVAWKLGEFLREVLALPAAVYESPTFHYKEGLEEEIFPAENK-VTVNDFMATLMSEPGPSCLVWLPLVHRLATVETIVHPTVCSVCHKENFTGFRYRCQRCHAYQLCQECFWHGKTSLNHQNDHEVKEY-SSYKSPSKQIGHSLRKSFRCVPEKTV-------------QVLPRFPDQPEKTLNLSHIVPPSPLPSHNGFSDPSGLVHGHHGPHPG----LPGQHGLFDRSSTLDSRATGRSLDSASGTAGTTMSRVAAASAN------DEEHRLIARYAARLAQENRAPSNLPDNATPIGTDNS----------------------RAQRELIAQLESKNKEIMREIARLRRQQETEQMA--------------------PENPALINELRALRQRKGELEGHLGALQDSRRQLMEQLEGLMRMLKNQQTASPRSTPNSSPRSGKSPPMPGGA----------GILGTSPMSAL 550
BLAST of Dystrobrevin vs. Ensembl Fly
Match: Dyb (gene:FBgn0033739 transcript:FBtr0305077) HSP 1 Score: 339.347 bits (869), Expect = 3.383e-102 Identity = 219/622 (35.21%), Postives = 323/622 (51.93%), Query Frame = 2
Query: 248 LINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLN----TSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSL 2101
++ +++ + FDSIRFA+YRTA KLRYIQ+ T L L+D+ V+E+FR+ GL +E + ++E +++ LY L+ RLP Q+ + +L+ WLL +Y + +G++ V ++KVAL+T+ SGK +DK +Y F+ ++D +G L+ + ++L ++L L V+E P F Y + I +K + + +F+ ++++PGP CL+WL + HRLA +E + H C CH+E GFRY+CQRCH Y LCQ+CFW G T+ NH N H+VKEY SS KS S+Q GH+LRKS+ TV Q R D ++ + LP N S +G P Q+ F S + S S + +G +++ S + D+EHRLIARYA+ L S L T I DN+ ++Q+ELIA+LE+KNKEI+REI RLR +Q+ A NP L+ ELR LR RK ELE + +LQ+SR +LM+QLE LMR+L S S NS+ S KS M A G+ G +P+S+L
Sbjct: 18 ILQDLRLQTFDSIRFASYRTASKLRYIQKSTNLHLVDIWNVIEAFRENGLNTLEPQSEVSVARLETLVSSLYHNLNKRLPTAQQVP---VDSKAGLLLNWLLAAYTSDNSGKIRVFSIKVALATMCSGKLVDKLRYIFSQISDGAGQLVAWKLGEFLREVLALPAAVYESPTFHYKEGLEEEIFPAENK-VTVNDFMATLMSEPGPSCLVWLPLVHRLATVETIVHPTVCSVCHKENFTGFRYRCQRCHAYQLCQECFWHGKTSLNHQNDHEVKEY-SSYKSPSKQIGHSLRKSFRCVPEKTV-------------QVLPRFPDQPEKTLNLSHIVPPSPLPSHNGFSDPSGLVHGHHGPHPG----LPGQHGLFDRSSTLDSRATGRSLDSASGTAGTTMSRVAAASAN------DEEHRLIARYAARLAQENRAPSNLPDNATPIGTDNS----------------------RAQRELIAQLESKNKEIMREIARLRRQQETEQMA--------------------PENPALINELRALRQRKGELEGHLGALQDSRRQLMEQLEGLMRMLKNQQTASPRSTPNSSPRSGKSPPMPGGA----------GILGTSPMSAL 559
BLAST of Dystrobrevin vs. Ensembl Fly
Match: Dyb (gene:FBgn0033739 transcript:FBtr0308613) HSP 1 Score: 340.502 bits (872), Expect = 4.085e-102 Identity = 219/622 (35.21%), Postives = 323/622 (51.93%), Query Frame = 2
Query: 248 LINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLN----TSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSL 2101
++ +++ + FDSIRFA+YRTA KLRYIQ+ T L L+D+ V+E+FR+ GL +E + ++E +++ LY L+ RLP Q+ + +L+ WLL +Y + +G++ V ++KVAL+T+ SGK +DK +Y F+ ++D +G L+ + ++L ++L L V+E P F Y + I +K + + +F+ ++++PGP CL+WL + HRLA +E + H C CH+E GFRY+CQRCH Y LCQ+CFW G T+ NH N H+VKEY SS KS S+Q GH+LRKS+ TV Q R D ++ + LP N S +G P Q+ F S + S S + +G +++ S + D+EHRLIARYA+ L S L T I DN+ ++Q+ELIA+LE+KNKEI+REI RLR +Q+ A NP L+ ELR LR RK ELE + +LQ+SR +LM+QLE LMR+L S S NS+ S KS M A G+ G +P+S+L
Sbjct: 9 ILQDLRLQTFDSIRFASYRTASKLRYIQKSTNLHLVDIWNVIEAFRENGLNTLEPQSEVSVARLETLVSSLYHNLNKRLPTAQQVP---VDSKAGLLLNWLLAAYTSDNSGKIRVFSIKVALATMCSGKLVDKLRYIFSQISDGAGQLVAWKLGEFLREVLALPAAVYESPTFHYKEGLEEEIFPAENK-VTVNDFMATLMSEPGPSCLVWLPLVHRLATVETIVHPTVCSVCHKENFTGFRYRCQRCHAYQLCQECFWHGKTSLNHQNDHEVKEY-SSYKSPSKQIGHSLRKSFRCVPEKTV-------------QVLPRFPDQPEKTLNLSHIVPPSPLPSHNGFSDPSGLVHGHHGPHPG----LPGQHGLFDRSSTLDSRATGRSLDSASGTAGTTMSRVAAASAN------DEEHRLIARYAARLAQENRAPSNLPDNATPIGTDNS----------------------RAQRELIAQLESKNKEIMREIARLRRQQETEQMA--------------------PENPALINELRALRQRKGELEGHLGALQDSRRQLMEQLEGLMRMLKNQQTASPRSTPNSSPRSGKSPPMPGGA----------GILGTSPMSAL 550
BLAST of Dystrobrevin vs. Ensembl Zebrafish
Match: dtna (dystrobrevin, alpha [Source:ZFIN;Acc:ZDB-GENE-070117-2]) HSP 1 Score: 331.643 bits (849), Expect = 9.584e-99 Identity = 206/597 (34.51%), Postives = 318/597 (53.27%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQ-NQSQSRNVDNNQRMMKTPAGQASPCL----------PYRNTVSRIQAADNGQF-RASPNQTMMTTDQNVNFS-GVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYH-----DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVL 1966
MA ++L EM+A DSIR + YRTACKLR+IQ+R L L+D+ ++E FR+ L +E + + ++ +++ ++ QL+ RLP Q++ + +SI L+ +LL +YD G G++S +K+AL+TL GK +DK +Y F+ ++DP+G +I ++F+Q+L ++L + V VFEGP+F Y Q+++ + K + + FL+ ++DP PQCL+WL + HRLAN+ENV H V C CH + ++GFRY+CQ+C +Y LCQ+CFW G +G+HSN H +KEY S KS +++ AL KS ++C Y Q + + + ++ N + P + + PY + + + F R +P+ + + V +S ++ + H + + N K+ F H DDEH LIARYAS L + G S+ D S K Q++LIA+LE KNK +Q ++ +QQ+ A DK NP LL ELR LR RK+ELE RM++LQESR ELM QLE LM +L
Sbjct: 12 MADRRQLFAEMRALDLDSIRLSTYRTACKLRFIQKRCNLHLVDIWNIIEVFRENRLNSVELNTEFSVSHLQAILSTIFQQLNKRLPTTHQIN---VDQSISYLLNFLLTAYDQEGVGKISAFVMKMALATLCGGKILDKLRYIFSQISDPNGLMIYSQFDQFLREVLKVPVSVFEGPSFGYTEQSTRSCF-PQEKKVTLNVFLDTFMSDPPPQCLVWLPLMHRLANVENVFHPVECSYCHSQSMMGFRYRCQQCDNYQLCQECFWRGHASGSHSNQHQMKEYM-SWKSPAKKLSDALSKS--------LSCAASREPAYPQFSDTPEKTLNLNHIVPPRPVATGNEYMLSHSMPSSGNPYSSKAAHDETNQMKLFSRTTPD---LLKGKGVQYSLDIADRLADEHILIGL-----------YVNLLQKERSCFQHSSKNQDDEHCLIARYASRLAADEVAAKGRVPTDISLCLD----------------------SNKQQRQLIAELENKNK---EILQEIQRLRQQHEEASQPPLDKNQ------------QNPMLLAELRLLRQRKEELEQRMSALQESRRELMVQLEQLMLLL 544
BLAST of Dystrobrevin vs. Ensembl Zebrafish
Match: dtna (dystrobrevin, alpha [Source:ZFIN;Acc:ZDB-GENE-070117-2]) HSP 1 Score: 328.176 bits (840), Expect = 2.182e-97 Identity = 209/600 (34.83%), Postives = 319/600 (53.17%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKT----PAGQASPCL----------PYRNTVSRIQAADNGQF-RASPNQTMMTTDQNVNFS-GVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYH-----DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVL 1966
MA ++L EM+A DSIR + YRTACKLR+IQ+R L L+D+ ++E FR+ L +E + + ++ +++ ++ QL+ RLP Q++ + +SI L+ +LL +YD G G++S +K+AL+TL GK +DK +Y F+ ++DP+G +I ++F+Q+L ++L + V VFEGP+F Y Q+++ + K + + FL+ ++DP PQCL+WL + HRLAN+ENV H V C CH + ++GFRY+CQ+C +Y LCQ+CFW G +G+HSN H +KEY S KS +++ AL KS ++C Y Q N ++ T P + + PY + + + F R +P+ + + V +S ++ + H + + N K+ F H DDEH LIARYAS L + +P TD I + L S+ K Q++LIA+LE KNK +Q ++ +QQ+ A DK NP LL ELR LR RK+ELE RM++LQESR ELM QLE LM +L
Sbjct: 12 MADRRQLFAEMRALDLDSIRLSTYRTACKLRFIQKRCNLHLVDIWNIIEVFRENRLNSVELNTEFSVSHLQAILSTIFQQLNKRLPTTHQIN---VDQSISYLLNFLLTAYDQEGVGKISAFVMKMALATLCGGKILDKLRYIFSQISDPNGLMIYSQFDQFLREVLKVPVSVFEGPSFGYTEQSTRSCF-PQEKKVTLNVFLDTFMSDPPPQCLVWLPLMHRLANVENVFHPVECSYCHSQSMMGFRYRCQQCDNYQLCQECFWRGHASGSHSNQHQMKEYM-SWKSPAKKLSDALSKS--------LSCAASREPAYPQFSDTPEKTLNLNHIVGTWPPRPVATGNEYMLSHSMPSSGNPYSSKAAHDETNQMKLFSRTTPD---LLKGKGVQYSLDIADRLADEHILIGL-----------YVNLLQKERSCFQHSSKNQDDEHCLIARYASRLAADEVAAQKGRVP--------TD---ISLCLDSN----------KQQRQLIAELENKNK---EILQEIQRLRQQHEEASQPPLDKNQ------------QNPMLLAELRLLRQRKEELEQRMSALQESRRELMVQLEQLMLLL 548
BLAST of Dystrobrevin vs. Ensembl Zebrafish
Match: dtna (dystrobrevin, alpha [Source:ZFIN;Acc:ZDB-GENE-070117-2]) HSP 1 Score: 328.176 bits (840), Expect = 2.182e-97 Identity = 209/600 (34.83%), Postives = 319/600 (53.17%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKT----PAGQASPCL----------PYRNTVSRIQAADNGQF-RASPNQTMMTTDQNVNFS-GVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYH-----DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVL 1966
MA ++L EM+A DSIR + YRTACKLR+IQ+R L L+D+ ++E FR+ L +E + + ++ +++ ++ QL+ RLP Q++ + +SI L+ +LL +YD G G++S +K+AL+TL GK +DK +Y F+ ++DP+G +I ++F+Q+L ++L + V VFEGP+F Y Q+++ + K + + FL+ ++DP PQCL+WL + HRLAN+ENV H V C CH + ++GFRY+CQ+C +Y LCQ+CFW G +G+HSN H +KEY S KS +++ AL KS ++C Y Q N ++ T P + + PY + + + F R +P+ + + V +S ++ + H + + N K+ F H DDEH LIARYAS L + +P TD I + L S+ K Q++LIA+LE KNK +Q ++ +QQ+ A DK NP LL ELR LR RK+ELE RM++LQESR ELM QLE LM +L
Sbjct: 12 MADRRQLFAEMRALDLDSIRLSTYRTACKLRFIQKRCNLHLVDIWNIIEVFRENRLNSVELNTEFSVSHLQAILSTIFQQLNKRLPTTHQIN---VDQSISYLLNFLLTAYDQEGVGKISAFVMKMALATLCGGKILDKLRYIFSQISDPNGLMIYSQFDQFLREVLKVPVSVFEGPSFGYTEQSTRSCF-PQEKKVTLNVFLDTFMSDPPPQCLVWLPLMHRLANVENVFHPVECSYCHSQSMMGFRYRCQQCDNYQLCQECFWRGHASGSHSNQHQMKEYM-SWKSPAKKLSDALSKS--------LSCAASREPAYPQFSDTPEKTLNLNHIVGTWPPRPVATGNEYMLSHSMPSSGNPYSSKAAHDETNQMKLFSRTTPD---LLKGKGVQYSLDIADRLADEHILIGL-----------YVNLLQKERSCFQHSSKNQDDEHCLIARYASRLAADEVAAQKGRVP--------TD---ISLCLDSN----------KQQRQLIAELENKNK---EILQEIQRLRQQHEEASQPPLDKNQ------------QNPMLLAELRLLRQRKEELEQRMSALQESRRELMVQLEQLMLLL 548
BLAST of Dystrobrevin vs. Ensembl Zebrafish
Match: dtnba (dystrobrevin, beta a [Source:ZFIN;Acc:ZDB-GENE-030131-3967]) HSP 1 Score: 315.849 bits (808), Expect = 5.834e-94 Identity = 197/586 (33.62%), Postives = 310/586 (52.90%), Query Frame = 2
Query: 224 IGMAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSS 1981
+ MA K+L +MK + +D+IR + YRTACKLR++Q++ L L+DV ++E+FR GL ++ + ++E ++ +Y QL+ RLP Q+ + + +L+ ++ ++DT GRL+V ++K+ LS L GK +DK +Y F+ ++D GA+ ++F+ +L + L L VFEGP+F Y ++ + K +++ FL+ +++DP PQCL+WL + HR+ N+ENV H V C C + + GFRY+CQ+C +Y LCQ+CFW G +GNHSN HD+KE+ SS KS +++ G A+ KS V S Y + + N+ N + P G + P +T S SP + + T +Q + HA SS + + P + D+EH+LIARYAS L + D HT+ D + ++ N K Q+ELI +LE KN+ +Q ++ + ++ A ++ + NP LL ELR LR RKDELE RM+SLQESR ELM QLE LM++L ++
Sbjct: 9 VVMADRKQLFMDMKTQNYDTIRLSTYRTACKLRFVQKKCNLHLVDVWNMIEAFRDNGLNTLDVCTEISVARLETILTCIYQQLNKRLPTTHQIS---VQHNTSLLLNFMATAHDTDAQGRLTVFSVKMMLSVLCGGKLVDKLRYIFSQISDSHGAMEMSKFDHFLREALKLPAAVFEGPSFGYLDHLARSCF-PQQKKVMLNMFLDALMSDPPPQCLIWLPLVHRMGNVENVHHPVSCSFCRSDGMTGFRYRCQQCFNYQLCQNCFWRGHASGNHSNHHDMKEH-SSWKSPAKKLGRAISKSL-----GCVPSREPSHPIYPEYPEKPLNLSNI--VPPRPIGNMNEPAPPLSTGS------------SPTKRLPTL-------AAAQRMNEEHALI-AAYVNKLQSSPRALDSPVRS------DEEHKLIARYASRLAT--------DPGHTARPADFS-------------YDTN-----KQQRELIMQLENKNR---EILQEIQRLRVEHEQACQPTPER------------VQQNPTLLAELRQLRQRKDELEQRMSSLQESRRELMVQLEGLMKLLKAQAA 515
BLAST of Dystrobrevin vs. Ensembl Zebrafish
Match: dtnbb (dystrobrevin, beta b [Source:ZFIN;Acc:ZDB-GENE-070117-3]) HSP 1 Score: 284.263 bits (726), Expect = 3.735e-83 Identity = 125/300 (41.67%), Postives = 203/300 (67.67%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
M ++L EM+A+ FD IR + YRTACKLR++Q+R L L+DV ++E+FR GL ++ + ++ +++E +++ ++ QL+ RLP Q++ + +SI +L+ +++ +YD+ G G+L+V A+K L+T+ GK +DK +Y F+ ++D +G ++ +F+Q+L ++L L VFEGP+F Y + + + K I++ FL+ ++ADP PQCL+WL + HRLAN+ENV H V C C E ++GFRY+CQ+CH Y LCQ CFW G +G HSN H +KE+ SS KS +++ HA+ KS
Sbjct: 12 MVEKRQLFMEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDVWNMIEAFRDNGLSTLDHNAEINVSRLETILSSIFYQLNKRLPTTHQIN---VEQSIGLLLNFIVATYDSEGHGKLTVFAMKAMLATMCGGKILDKLRYVFSQISDSNGVMVFAKFDQFLREVLKLPTAVFEGPSFGYTEHSVR-TCFPQQKKILLNTFLDVLMADPPPQCLVWLPLMHRLANVENVFHPVECSYCRSESMMGFRYRCQQCHGYQLCQSCFWRGHASGPHSNQHQMKEH-SSWKSPAKKLSHAISKS 306 HSP 2 Score: 83.1889 bits (204), Expect = 9.461e-16 Identity = 79/201 (39.30%), Postives = 107/201 (53.23%), Query Frame = 2
Query: 1496 DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
D+EHRLIARYA+ L + S ++T P ++ D + K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LRHRKDELE RM++LQESR ELM QLE LMR+L + + +S+ + S +M + +A + T + Q L GV
Sbjct: 343 DEEHRLIARYAARLAAEAS--------------NSTQCPPSDLSFNFD--------ANKQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPTLLAELRLLRHRKDELERRMSALQESRRELMVQLEGLMRLLKAQTGTSPHSSPSHSASCTMPMPIRSTSAGSTPTHTPQDCLAGV 506
BLAST of Dystrobrevin vs. Ensembl Xenopus
Match: dtna (dystrobrevin alpha [Source:NCBI gene;Acc:779813]) HSP 1 Score: 347.051 bits (889), Expect = 3.076e-104 Identity = 216/644 (33.54%), Postives = 349/644 (54.19%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKT-PA--------GQASPC--LPYRNTVSRIQAADNGQ----FRASPNQTMMTTDQNVNFS-GVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRST-----HSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
MA ++L EM+A+ D IR + YRTACKLR++Q++ L L+D+ ++E+ R+ L ++ + L+ ++E +++ ++ QL+ R+P Q++ + +SI +++ +LL +YD+ G G+++V A+K+AL+TL GK MDK +Y +++++D +G ++ R++Q+L ++L L +FEGP+F Y QA++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G +G+HSN H +KEYT S KS +++ AL KS ++C + Q N ++ P + PC P+ N +S ++ + Q RA+P + + + +S V+ + H V ++ + + PS+ D+EHRLIARYA+ L + S+ G D+ T DA K Q++LIA+LE KN+ +Q ++ + ++ A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L T + S+ T SR + + +A + T + Q LTGV
Sbjct: 12 MAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNIIEALRENSLNNVDPNVELNVARLEAVLSTVFFQLNKRMPTTHQIN---VEQSISLMLNFLLTAYDSEGHGKITVFAVKMALATLCGGKIMDKLRYIYSMISDTNGMMVYGRYDQFLREVLKLPTAIFEGPSFGYTEQAARSCF-SQQKKVTLNSFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYT-SWKSPAKKLSTALSKS--------LSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDNIFSHSVPCSGSPFTNKISPHKSTEVEQSKYLARAAPT---LLKGKGLQYSLDVADRLADEHVLIGVYANMLQNNHSRMLDSPSR------LDEEHRLIARYAARLAAENSSAQAQQRGGADISFT------IDA-------------------NKQQRQLIAELENKNR---EILQEIQRLRIEHEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKTQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGV 593
BLAST of Dystrobrevin vs. Ensembl Xenopus
Match: dtna (dystrobrevin alpha [Source:NCBI gene;Acc:779813]) HSP 1 Score: 347.051 bits (889), Expect = 8.377e-104 Identity = 216/644 (33.54%), Postives = 349/644 (54.19%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKT-PA--------GQASPC--LPYRNTVSRIQAADNGQ----FRASPNQTMMTTDQNVNFS-GVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRST-----HSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
MA ++L EM+A+ D IR + YRTACKLR++Q++ L L+D+ ++E+ R+ L ++ + L+ ++E +++ ++ QL+ R+P Q++ + +SI +++ +LL +YD+ G G+++V A+K+AL+TL GK MDK +Y +++++D +G ++ R++Q+L ++L L +FEGP+F Y QA++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G +G+HSN H +KEYT S KS +++ AL KS ++C + Q N ++ P + PC P+ N +S ++ + Q RA+P + + + +S V+ + H V ++ + + PS+ D+EHRLIARYA+ L + S+ G D+ T DA K Q++LIA+LE KN+ +Q ++ + ++ A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L T + S+ T SR + + +A + T + Q LTGV
Sbjct: 18 MAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNIIEALRENSLNNVDPNVELNVARLEAVLSTVFFQLNKRMPTTHQIN---VEQSISLMLNFLLTAYDSEGHGKITVFAVKMALATLCGGKIMDKLRYIYSMISDTNGMMVYGRYDQFLREVLKLPTAIFEGPSFGYTEQAARSCF-SQQKKVTLNSFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYT-SWKSPAKKLSTALSKS--------LSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDNIFSHSVPCSGSPFTNKISPHKSTEVEQSKYLARAAPT---LLKGKGLQYSLDVADRLADEHVLIGVYANMLQNNHSRMLDSPSR------LDEEHRLIARYAARLAAENSSAQAQQRGGADISFT------IDA-------------------NKQQRQLIAELENKNR---EILQEIQRLRIEHEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKTQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGV 599
BLAST of Dystrobrevin vs. Ensembl Xenopus
Match: dtna (dystrobrevin alpha [Source:NCBI gene;Acc:779813]) HSP 1 Score: 339.732 bits (870), Expect = 4.529e-101 Identity = 216/651 (33.18%), Postives = 349/651 (53.61%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKT-PA--------GQASPC--LPYRNTVSRIQAADNGQ----FRASPNQTMMTTDQNVNFS-GVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRST-----HSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVL-------NTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
MA ++L EM+A+ D IR + YRTACKLR++Q++ L L+D+ ++E+ R+ L ++ + L+ ++E +++ ++ QL+ R+P Q++ + +SI +++ +LL +YD+ G G+++V A+K+AL+TL GK MDK +Y +++++D +G ++ R++Q+L ++L L +FEGP+F Y QA++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G +G+HSN H +KEYT S KS +++ AL KS ++C + Q N ++ P + PC P+ N +S ++ + Q RA+P + + + +S V+ + H V ++ + + PS+ D+EHRLIARYA+ L + S+ G D+ T DA K Q++LIA+LE KN+ +Q ++ + ++ A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L T + S+ T SR + + +A + T + Q LTGV
Sbjct: 18 MAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNIIEALRENSLNNVDPNVELNVARLEAVLSTVFFQLNKRMPTTHQIN---VEQSISLMLNFLLTAYDSEGHGKITVFAVKMALATLCGGKIMDKLRYIYSMISDTNGMMVYGRYDQFLREVLKLPTAIFEGPSFGYTEQAARSCF-SQQKKVTLNSFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYT-SWKSPAKKLSTALSKS--------LSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDNIFSHSVPCSGSPFTNKISPHKSTEVEQSKYLARAAPT---LLKGKGLQYSLDVADRLADEHVLIGVYANMLQNNHSRMLDSPSR------LDEEHRLIARYAARLAAENSSAQAQQRGGADISFT------IDA-------------------NKQQRQLIAELENKNR---EILQEIQRLRIEHEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEQELRQETQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGV 606
BLAST of Dystrobrevin vs. Ensembl Xenopus
Match: dtna (dystrobrevin alpha [Source:NCBI gene;Acc:779813]) HSP 1 Score: 339.347 bits (869), Expect = 5.358e-101 Identity = 216/651 (33.18%), Postives = 349/651 (53.61%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKT-PA--------GQASPC--LPYRNTVSRIQAADNGQ----FRASPNQTMMTTDQNVNFS-GVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRST-----HSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVL-------NTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
MA ++L EM+A+ D IR + YRTACKLR++Q++ L L+D+ ++E+ R+ L ++ + L+ ++E +++ ++ QL+ R+P Q++ + +SI +++ +LL +YD+ G G+++V A+K+AL+TL GK MDK +Y +++++D +G ++ R++Q+L ++L L +FEGP+F Y QA++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G +G+HSN H +KEYT S KS +++ AL KS ++C + Q N ++ P + PC P+ N +S ++ + Q RA+P + + + +S V+ + H V ++ + + PS+ D+EHRLIARYA+ L + S+ G D+ T DA K Q++LIA+LE KN+ +Q ++ + ++ A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L T + S+ T SR + + +A + T + Q LTGV
Sbjct: 12 MAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNIIEALRENSLNNVDPNVELNVARLEAVLSTVFFQLNKRMPTTHQIN---VEQSISLMLNFLLTAYDSEGHGKITVFAVKMALATLCGGKIMDKLRYIYSMISDTNGMMVYGRYDQFLREVLKLPTAIFEGPSFGYTEQAARSCF-SQQKKVTLNSFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYT-SWKSPAKKLSTALSKS--------LSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDNIFSHSVPCSGSPFTNKISPHKSTEVEQSKYLARAAPT---LLKGKGLQYSLDVADRLADEHVLIGVYANMLQNNHSRMLDSPSR------LDEEHRLIARYAARLAAENSSAQAQQRGGADISFT------IDA-------------------NKQQRQLIAELENKNR---EILQEIQRLRIEHEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEQELRQETQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGV 600
BLAST of Dystrobrevin vs. Ensembl Xenopus
Match: dtna (dystrobrevin alpha [Source:NCBI gene;Acc:779813]) HSP 1 Score: 291.582 bits (745), Expect = 1.088e-84 Identity = 125/300 (41.67%), Postives = 208/300 (69.33%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ D IR + YRTACKLR++Q++ L L+D+ ++E+ R+ L ++ + L+ ++E +++ ++ QL+ R+P Q++ + +SI +++ +LL +YD+ G G+++V A+K+AL+TL GK MDK +Y +++++D +G ++ R++Q+L ++L L +FEGP+F Y QA++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G +G+HSN H +KEYT S KS +++ AL KS
Sbjct: 12 MAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNIIEALRENSLNNVDPNVELNVARLEAVLSTVFFQLNKRMPTTHQIN---VEQSISLMLNFLLTAYDSEGHGKITVFAVKMALATLCGGKIMDKLRYIYSMISDTNGMMVYGRYDQFLREVLKLPTAIFEGPSFGYTEQAARSCF-SQQKKVTLNSFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYT-SWKSPAKKLSTALSKS 306 HSP 2 Score: 81.2629 bits (199), Expect = 5.885e-15 Identity = 80/201 (39.80%), Postives = 105/201 (52.24%), Query Frame = 2
Query: 1496 DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
D+EHRLIARYA+ L + S+ + D+ T DA K Q++LIA+LE KN+EIL+EIQRLR+E + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L T + S+ T SR + + +A + T + Q LTGV
Sbjct: 421 DEEHRLIARYAARLAAENSS-AVTDISFT------IDA-------------------NKQQRQLIAELENKNREILQEIQRLRIE---HEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKTQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGV 580
BLAST of Dystrobrevin vs. Ensembl Mouse
Match: Dtnb (dystrobrevin, beta [Source:MGI Symbol;Acc:MGI:1203728]) HSP 1 Score: 327.02 bits (837), Expect = 3.296e-98 Identity = 221/626 (35.30%), Postives = 340/626 (54.31%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKE---YTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ S + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G ++ + +Q+L + L L VFEGP+F Y A + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C CH E ++GFRY+CQ+CH+Y LCQ+CFW G +G HSN H +KE + S +K S +L R+ V + R + N M T S +P R+Q + + PN + D++ + S + + H C+ V ++ PS+ D+EHRLIARYA+ L + ++++ TDA S F+ N K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L ++ +++ R M + +A + T Q L+GV
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVR-TCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHLVPPRPLTN---MNDTVVSHMSSGVP--TPTKRLQYSQD-----MPN---LLADEHALIA--SYVARLQH-CTRVLDS------------PSR------LDEEHRLIARYAARLAAEAG----------NMTRPPTDA--------SFNFDAN-----KQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGV 561
BLAST of Dystrobrevin vs. Ensembl Mouse
Match: Dtnb (dystrobrevin, beta [Source:MGI Symbol;Acc:MGI:1203728]) HSP 1 Score: 327.02 bits (837), Expect = 3.330e-98 Identity = 221/626 (35.30%), Postives = 340/626 (54.31%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKE---YTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ S + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G ++ + +Q+L + L L VFEGP+F Y A + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C CH E ++GFRY+CQ+CH+Y LCQ+CFW G +G HSN H +KE + S +K S +L R+ V + R + N M T S +P R+Q + + PN + D++ + S + + H C+ V ++ PS+ D+EHRLIARYA+ L + ++++ TDA S F+ N K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L ++ +++ R M + +A + T Q L+GV
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCF-PQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHLVPPRPLTN---MNDTVVSHMSSGVP--TPTKRLQYSQD-----MPN---LLADEHALIA--SYVARLQH-CTRVLDS------------PSR------LDEEHRLIARYAARLAAEAG----------NMTRPPTDA--------SFNFDAN-----KQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGV 561
BLAST of Dystrobrevin vs. Ensembl Mouse
Match: Dtnb (dystrobrevin, beta [Source:MGI Symbol;Acc:MGI:1203728]) HSP 1 Score: 285.804 bits (730), Expect = 6.953e-84 Identity = 128/300 (42.67%), Postives = 204/300 (68.00%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ S + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G ++ + +Q+L + L L VFEGP+F Y A + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C CH E ++GFRY+CQ+CH+Y LCQ+CFW G +G HSN H +KE+ SS KS +++ HA+ KS
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVR-TCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEH-SSWKSPAKKLSHAISKS 306 HSP 2 Score: 80.8777 bits (198), Expect = 4.582e-15 Identity = 78/201 (38.81%), Postives = 106/201 (52.74%), Query Frame = 2
Query: 1496 DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
D+EHRLIARYA+ L + ++++ TDA S F+ N K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L ++ +++ R M + +A + T Q L+GV
Sbjct: 369 DEEHRLIARYAARLAAEAG----------NMTRPPTDA--------SFNFDAN-----KQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGV 531
BLAST of Dystrobrevin vs. Ensembl Mouse
Match: Dtnb (dystrobrevin, beta [Source:MGI Symbol;Acc:MGI:1203728]) HSP 1 Score: 286.189 bits (731), Expect = 7.115e-84 Identity = 128/300 (42.67%), Postives = 204/300 (68.00%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ S + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G ++ + +Q+L + L L VFEGP+F Y A + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C CH E ++GFRY+CQ+CH+Y LCQ+CFW G +G HSN H +KE+ SS KS +++ HA+ KS
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVR-TCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEH-SSWKSPAKKLSHAISKS 306 HSP 2 Score: 78.1814 bits (191), Expect = 3.219e-14 Identity = 81/208 (38.94%), Postives = 105/208 (50.48%), Query Frame = 2
Query: 1496 DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKS-------RSM-----NQAANTISTFSRQSGLTGV 2083
D+EHRLIARYA+ L + ++++ TDA S F+ N K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L Q A S + R M + +A + T Q L+GV
Sbjct: 369 DEEHRLIARYAARLAAEAG----------NMTRPPTDA--------SFNFDAN-----KQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGV 538
BLAST of Dystrobrevin vs. Ensembl Mouse
Match: Dtnb (dystrobrevin, beta [Source:MGI Symbol;Acc:MGI:1203728]) HSP 1 Score: 285.804 bits (730), Expect = 1.768e-83 Identity = 128/300 (42.67%), Postives = 204/300 (68.00%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ S + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G ++ + +Q+L + L L VFEGP+F Y A + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C CH E ++GFRY+CQ+CH+Y LCQ+CFW G +G HSN H +KE+ SS KS +++ HA+ KS
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVR-TCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEH-SSWKSPAKKLSHAISKS 306 HSP 2 Score: 78.1814 bits (191), Expect = 3.720e-14 Identity = 81/208 (38.94%), Postives = 105/208 (50.48%), Query Frame = 2
Query: 1496 DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKS-------RSM-----NQAANTISTFSRQSGLTGV 2083
D+EHRLIARYA+ L + ++++ TDA S F+ N K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L Q A S + R M + +A + T Q L+GV
Sbjct: 399 DEEHRLIARYAARLAAEAG----------NMTRPPTDA--------SFNFDAN-----KQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGV 568
BLAST of Dystrobrevin vs. UniProt/SwissProt
Match: sp|O60941|DTNB_HUMAN (Dystrobrevin beta OS=Homo sapiens OX=9606 GN=DTNB PE=1 SV=1) HSP 1 Score: 333.183 bits (853), Expect = 2.588e-99 Identity = 244/761 (32.06%), Postives = 368/761 (48.36%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHT----NQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSLLPSNSGQPLKLHGYGSPMTTHRSLSYTADSNRSVTMGPHSILPQPRFNTLTRHSRTFSADEGLGGFASQPRRTFTSGNRTLESLGVDTTDYYLKQSSDKAKQNNSLSKEMDLRQNLLMAADNVTNAMTGLVRN 2500
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ + + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G +I ++F+Q+L ++L L VFEGP+F Y + + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C C E ++GFRY+CQ+CH+Y LCQ+CFW G G HSN H +KE+ SS KS +++ HA+ K ++ C + V Q P P N N + + + T + + +S IPS H ++ + L+H + PS+ D+EHRLIARYA+ L + + P T +S + F+ N K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L K QAA +G +P HG G PM P P +T + T + L G + F G R +LR +LL+AAD++TN M+ LV+
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYTEHSVRTCFPQQRK-IMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKEH-SSWKSPAKKLSHAISK--------SLGCVPTREPPHP--------VFPEQPEKPLDLAHIVPPRPLTNM--------NDTMVSHMSSGVPTPTKRLQYS--QDIPS--HLADEHALIASYVARLQHCARVLDSPSR------LDEEHRLIARYAARLAAEAG---NVTRPPTDLSFN---------------FDAN-----KQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLL---------------KEEEQKQAAQA-------TGSPHTSP--------------THGGGRPM------------------------PMPVRSTSAGSTPTHCPQDSLSGVGGDVQEAFAQGTRR------------------------------NLRNDLLVAADSITNTMSSLVKE 605
BLAST of Dystrobrevin vs. UniProt/SwissProt
Match: sp|P84060|DTNB_RAT (Dystrobrevin beta OS=Rattus norvegicus OX=10116 GN=Dtnb PE=1 SV=2) HSP 1 Score: 328.946 bits (842), Expect = 1.525e-97 Identity = 219/626 (34.98%), Postives = 338/626 (53.99%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKE---YTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ + + +++E +I+ +Y QL+ RLP+ Q++ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G ++ + +Q+L + L L VFEGP+F Y A + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C CH E ++GFRY+CQ+CH+Y LCQ+CFW G G HSN H +KE + S +K S +L R+ V + R + N M + P R+Q + PN + D++ + S + + H C+ V ++ PS+ D+EHRLIARYA+ L + ++++ TDA S F+ N K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L ++ +++ RSM + +A + T Q L+GV
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHATEISVSRLETVISSIYYQLNKRLPSTHQIN---VEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVR-TCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKELSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVP-----TPTKRLQYGQD-----MPN---LLADEHALIA--SYVARLQH-CTRVLDS------------PSR------LDEEHRLIARYAARLAAEAG----------NMTRPPTDA--------SFNFDAN-----KQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRSMPMPVRSTSAGSTPTHGPQDSLSGV 561
BLAST of Dystrobrevin vs. UniProt/SwissProt
Match: sp|O70585|DTNB_MOUSE (Dystrobrevin beta OS=Mus musculus OX=10090 GN=Dtnb PE=1 SV=3) HSP 1 Score: 285.804 bits (730), Expect = 6.853e-82 Identity = 128/300 (42.67%), Postives = 204/300 (68.00%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ FD IR + YRTACKLR++Q+R L L+D+ ++E+FR GL ++ S + +++E +I+ +Y QL+ RLP+ Q+ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D +G ++ + +Q+L + L L VFEGP+F Y A + + K I++ FL+ M+ADP PQCL+WL + HRLA++ENV H V C CH E ++GFRY+CQ+CH+Y LCQ+CFW G +G HSN H +KE+ SS KS +++ HA+ KS
Sbjct: 12 MAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQIS---VEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVR-TCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEH-SSWKSPAKKLSHAISKS 306 HSP 2 Score: 80.8777 bits (198), Expect = 4.588e-14 Identity = 78/201 (38.81%), Postives = 106/201 (52.74%), Query Frame = 2
Query: 1496 DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
D+EHRLIARYA+ L + ++++ TDA S F+ N K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L ++ +++ R M + +A + T Q L+GV
Sbjct: 399 DEEHRLIARYAARLAAEAG----------NMTRPPTDA--------SFNFDAN-----KQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGV 561
BLAST of Dystrobrevin vs. UniProt/SwissProt
Match: sp|Q9Y4J8|DTNA_HUMAN (Dystrobrevin alpha OS=Homo sapiens OX=9606 GN=DTNA PE=1 SV=2) HSP 1 Score: 286.574 bits (732), Expect = 2.221e-81 Identity = 130/300 (43.33%), Postives = 208/300 (69.33%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ D IR + YRTACKLR++Q++ L L+D+ V+E+ R+ L ++ + L+ +++E +++ ++ QL+ R+P Q+H + +SI +L+ +LL ++D G G++SV A+K+AL+TL GK MDK +Y F++++D SG ++ R++Q+L ++L L VFEGP+F Y Q+++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G G+HSN H +KEYT S KS +++ +AL KS
Sbjct: 12 MAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVLSTIFYQLNKRMPTTHQIH---VEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYTEQSARSCF-SQQKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQHQMKEYT-SWKSPAKKLTNALSKS 306 HSP 2 Score: 86.6557 bits (213), Expect = 8.376e-16 Identity = 81/201 (40.30%), Postives = 106/201 (52.74%), Query Frame = 2
Query: 1496 DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
D+EHRLIARYA+ L + S+ S AP I + ++ K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L T + S+ T SR + + +A + T + Q LTGV
Sbjct: 431 DEEHRLIARYAARLAAESSS---------SQPPQQRSAPDISFTIDAN----------KQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKTQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGV 597
BLAST of Dystrobrevin vs. UniProt/SwissProt
Match: sp|Q9D2N4|DTNA_MOUSE (Dystrobrevin alpha OS=Mus musculus OX=10090 GN=Dtna PE=1 SV=2) HSP 1 Score: 286.189 bits (731), Expect = 3.231e-81 Identity = 130/300 (43.33%), Postives = 207/300 (69.00%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ D IR + YRTACKLR++Q++ L L+D+ V+E+ R+ L ++ + L+ ++E +++ ++ QL+ R+P Q+H + +SI +L+ +LL ++D G G++SV A+K+AL+TL GK MDK +Y F++++D SG ++ R++Q+L ++L L VFEGP+F Y Q+++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G G+HSN H +KEYT S KS +++ +AL KS
Sbjct: 12 MAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNIELNVARLEAVLSTIFYQLNKRMPTTHQIH---VEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYTEQSARSCF-SQQKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQHQMKEYT-SWKSPAKKLTNALSKS 306 HSP 2 Score: 81.2629 bits (199), Expect = 3.696e-14 Identity = 81/208 (38.94%), Postives = 106/208 (50.96%), Query Frame = 2
Query: 1496 DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLN-------TSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
D+EHRLIARYA+ L + S+ S AP I + ++ K Q++LIA+LE KN+EIL+EIQRLR+E + A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L T +S S+ T SR + + +A T + Q LTGV
Sbjct: 428 DEEHRLIARYAARLAAESSS---------SQPTQQRSAPDISFTIDAN----------KQQRQLIAELENKNREILQEIQRLRVE---HEQASQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQGTQGASSPRSSPSHTISRPIPMPIRSASACPTPTHTPQDSLTGV 601
BLAST of Dystrobrevin vs. TrEMBL
Match: A0A4S2LEN9 (ZZ-type domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009439 PE=4 SV=1) HSP 1 Score: 407.527 bits (1046), Expect = 3.224e-119 Identity = 188/311 (60.45%), Postives = 235/311 (75.56%), Query Frame = 2
Query: 236 GFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLY-LMESSCNLDRTQIEMMIAQLYTQLSNRLPAGD-----------QLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSW 1132
GFKRL+ EMK +QFD+IRFAAYRTA KLRYIQQRT M++ VVE+FR+ GL+ L + + +LD ++A++Y+QLS P D PN++ + E+L+ +L+Y+ D T RL+V +LK+ALSTL + KP DKF+YHFTLL+DPSGALI +FE YL DLL L + VFEGPNF Y QA++ +L GRSK I+IE+FLE+MLADPGPQ L+WLTIFHRLA +EN+RHNVRCEGC RE + G RYKC RC HYNLCQDCFWTGVTT H+N HDVKEY+S+SKSHSRQFGH+LRKS+
Sbjct: 85 GFKRLLAEMKLRQFDTIRFAAYRTASKLRYIQQRTLFRFMELGRVVETFREFGLHQLNDPNASLDYAGTARILARIYSQLS--CPTTDVQTKSCSRTTPSFDPNVLRAASEILLSFLIYALDVCATARLTVNSLKIALSTLTNAKPSDKFRYHFTLLSDPSGALIQGKFETYLQDLLRLPISVFEGPNFFYTPQAAQAMLSGRSKNILIEDFLERMLADPGPQLLVWLTIFHRLAAVENIRHNVRCEGCKREPLFGLRYKCTRCQHYNLCQDCFWTGVTTEPHTNAHDVKEYSSASKSHSRQFGHSLRKSF 393
BLAST of Dystrobrevin vs. TrEMBL
Match: A0A3R7EUH4 (Dystrobrevin beta OS=Clonorchis sinensis OX=79923 GN=DTNB PE=4 SV=1) HSP 1 Score: 405.986 bits (1042), Expect = 1.077e-118 Identity = 187/311 (60.13%), Postives = 235/311 (75.56%), Query Frame = 2
Query: 236 GFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLY-LMESSCNLDRTQIEMMIAQLYTQLSNRLPAGD-----------QLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSW 1132
GFKRL+ EMK +QFD+IRFAAYRTA KLRYIQQRT M++ VVE+FR+ GL+ L + + +LD ++A++Y+QLS P D PN++ + E+L+ +L+Y+ D T RL+V +LK+ALSTL + KP +KF+YHFTLL+DPSGALI +FE YL DLL L + VFEGPNF Y QA++ +L GRSK I+IE+FLE+MLADPGPQ L+WLTIFHRLA +EN+RHNVRCEGC RE + G RYKC RC HYNLCQDCFWTGVTT H+N HDVKEY+S+SKSHSRQFGH+LRKS+
Sbjct: 85 GFKRLLAEMKLRQFDTIRFAAYRTASKLRYIQQRTLFRFMELGRVVETFREFGLHQLNDPNASLDYAGTARILARIYSQLSG--PTTDVQTKSGSKTTPSFDPNVLRAASEILLSFLIYALDVCATARLTVNSLKIALSTLTNAKPSEKFRYHFTLLSDPSGALIQGKFETYLQDLLRLPISVFEGPNFFYTPQAAQAMLSGRSKNILIEDFLERMLADPGPQLLVWLTIFHRLAAVENIRHNVRCEGCKREPLFGLRYKCTRCQHYNLCQDCFWTGVTTEPHTNAHDVKEYSSASKSHSRQFGHSLRKSF 393
BLAST of Dystrobrevin vs. TrEMBL
Match: A0A0X3NGC7 (Dystrobrevin-1 OS=Schistocephalus solidus OX=70667 GN=DTN1 PE=4 SV=1) HSP 1 Score: 404.831 bits (1039), Expect = 9.505e-118 Identity = 186/320 (58.13%), Postives = 233/320 (72.81%), Query Frame = 2
Query: 215 TQQIGMAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGD--------------QLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSW 1132
++ AGF+RL+ E+KAK+FD IRFAAYRTA KLRYIQ+RT L +D+ VVE+FR GL+L + S L+R E ++ ++Y L P D L ++ ++ E+L+GWL Y D + GRL+V LKVALSTLASGKP DKF+YHFTLLT+P+G L R E YL +LL LAVGVFE PNF+YNSQ SKFI+ GRSK+I++EEFLE+MLA+PGPQ WL +FHR+ +ENVRH V+CEGC RE IIG RYKC RC YNLCQDCFWTG+TT H+N+HDVKEYT+S+K HSRQFGH+LRKS+
Sbjct: 101 SENAAFAGFRRLLAELKAKKFDQIRFAAYRTASKLRYIQKRTLLGSLDIWRVVETFRDVGLHLADPSVTLNRQGTEQLLWRIYANLP---PPTDSPVVCDATGQRQILPLQSPMLTQAAEILLGWLTYILDPTNCGRLAVSGLKVALSTLASGKPADKFRYHFTLLTNPAGVLQIPRLETYLQELLSLAVGVFEEPNFSYNSQTSKFIISGRSKSILVEEFLERMLAEPGPQTFSWLKVFHRMVIVENVRHQVKCEGCKREPIIGLRYKCTRCPRYNLCQDCFWTGITTDAHTNSHDVKEYTTSTKQHSRQFGHSLRKSF 417
BLAST of Dystrobrevin vs. TrEMBL
Match: A0A0X3NXD5 (Dystrobrevin-1 OS=Schistocephalus solidus OX=70667 GN=DTN1 PE=4 SV=1) HSP 1 Score: 407.527 bits (1046), Expect = 4.910e-117 Identity = 186/320 (58.13%), Postives = 233/320 (72.81%), Query Frame = 2
Query: 215 TQQIGMAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQ--------------LHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSW 1132
++ AGF+RL+ E+KAK+FD IRFAAYRTA KLRYIQ+RT L +D+ VVE+FR GL+L + S L+R E ++ ++Y L P D L ++ ++ E+L+GWL Y D + GRL+V LKVALSTLASGKP DKF+YHFTLLT+P+G L R E YL +LL LAVGVFE PNF+YNSQ SKFI+ GRSK+I++EEFLE+MLA+PGPQ WL +FHR+ +ENVRH V+CEGC RE IIG RYKC RC YNLCQDCFWTG+TT H+N+HDVKEYT+S+K HSRQFGH+LRKS+
Sbjct: 101 SENAAFAGFRRLLAELKAKKFDQIRFAAYRTASKLRYIQKRTLLGSLDIWRVVETFRDVGLHLADPSVTLNRQGTEQLLWRIYANLP---PPTDSPVVCDATGQRQILPLQSPMLTQAAEILLGWLTYILDPTNCGRLAVSGLKVALSTLASGKPADKFRYHFTLLTNPAGVLQIPRLETYLQELLSLAVGVFEEPNFSYNSQTSKFIISGRSKSILVEEFLERMLAEPGPQTFSWLKVFHRMVIVENVRHQVKCEGCKREPIIGLRYKCTRCPRYNLCQDCFWTGITTDAHTNSHDVKEYTTSTKQHSRQFGHSLRKSF 417
BLAST of Dystrobrevin vs. TrEMBL
Match: A0A4E0RH39 (Dystrobrevin beta OS=Fasciola hepatica OX=6192 GN=D915_003256 PE=4 SV=1) HSP 1 Score: 397.127 bits (1019), Expect = 2.040e-114 Identity = 185/305 (60.66%), Postives = 232/305 (76.07%), Query Frame = 2
Query: 236 GFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLY-LMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPE-----SIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSW 1132
GFKRL+ EM+A+QFDSIRFAAYRTA KLRYIQQRT ++D+ VV++FR GL+ + E++ LD ++A++Y+ L+ + P + ++E+L+GWL Y+ D TGRL+V LK+ALS L + KP +KF+YHFTLL+DPSGALIP +FE YL DLL L V VFEGPNF Y QA++ +L GRSK I+IEEFL++MLADPG Q L+WLTIFHRLA++ENVRH+VRCE C RE I+G RYKC RC HYNLCQDCFWTG TT H+N HDVKEY+SSSKSHSRQFGH+LRKS+
Sbjct: 114 GFKRLLTEMRARQFDSIRFAAYRTASKLRYIQQRTMFGMVDLWRVVDTFRDFGLHQITENNATLDYASTGRLLARIYSHLNGAVEPNSGKPPRTLDVTAVHLAVELLLGWLAYALDICSTGRLTVTGLKIALSVLTNAKPAEKFRYHFTLLSDPSGALIPAKFEAYLQDLLKLPVSVFEGPNFFYTPQAAQSLLSGRSKNILIEEFLDRMLADPGSQLLVWLTIFHRLASVENVRHSVRCEVCKREPILGLRYKCTRCPHYNLCQDCFWTGATTDQHTNAHDVKEYSSSSKSHSRQFGHSLRKSF 418 HSP 2 Score: 63.5438 bits (153), Expect = 3.968e-6 Identity = 41/88 (46.59%), Postives = 56/88 (63.64%), Query Frame = 2
Query: 1838 NPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLN-TSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSS 2098
NP L+ EL+ LR RKDELE RM++LQ +R ELM QLE+L+R+L+ T QTN A + ++ + + +S S SGL TP SS
Sbjct: 855 NPKLVTELQALRQRKDELETRMSNLQRNRTELMLQLETLVRLLSVTGGPIQTNQA----RPQTTDAVESVLSDLS-PSGLLPSTPSSS 937
BLAST of Dystrobrevin vs. Ensembl Cavefish
Match: dtnba (dystrobrevin, beta a [Source:ZFIN;Acc:ZDB-GENE-030131-3967]) HSP 1 Score: 327.405 bits (838), Expect = 7.151e-99 Identity = 197/619 (31.83%), Postives = 326/619 (52.67%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGN-WDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGV 2083
MA +++ EM+ + FD+IR + YRTACKLR++Q++ +L L+DV ++E+FR GL ++ + L +++E +++ +Y QL+ RLP Q++ + +SI +L+ +LL ++++ G GRL+V ++K+ L+ + SGK +DK +Y F+ ++D +GA+ +RF+ +L + L L VFEGP+F Y +++ + K +++ FL+ ++ D PQCL+WL + HR+AN+ENV H V C C E ++GFRY+CQ+C Y LCQ+CFW G +GNHSN H +KE+ SS KS +++FG A+ KS C+P R + + +P + + + N+ G++ MN + + N +S + + PS+ D+EHRLIARY S L + + ++AP++ F+ N K Q++LIA+LE KN+ +Q ++ + ++ A +K NP LL ELR LR RKDELE RM++LQESR ELM QLE LM++L ++ ++ SR + + T +G +
Sbjct: 12 MAEKRQIFMEMRTQNFDTIRLSTYRTACKLRFVQKKCKLHLVDVWNMIEAFRDNGLNTLDHNTELSVSRLETIVSSIYFQLNKRLPTTHQIN---VQQSISLLLNFLLAAHESEGQGRLTVFSVKMMLAIMCSGKIVDKLRYIFSQISDSNGAMTVSRFDHFLRECLKLPSAVFEGPSFGYTEHSAQSCF-PQQKKVMLNMFLDTIMDDSPPQCLVWLPLMHRIANVENVVHPVSCSYCRSESMVGFRYRCQQCFSYQLCQNCFWRGHASGNHSNQHQMKEH-SSWKSPAKKFGRAISKSLG-------------------------------------------CVPSRE-------PPHPMYPENPERPLDLS--NIVVQGIAAAQRMNEEHALIAAYVNKLQTSPRALDSPSRT------DEEHRLIARYTSRLAT-----------------EPSNAPQLN-------FDVN-----KQQRQLIAELEHKNR---EILQEIQRLRLEHEQACQPTPEKAQ------------QNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQAAGSPQTSPGHRSSRPIPMPVRSTGTTPTHTGYPPI 523
BLAST of Dystrobrevin vs. Ensembl Cavefish
Match: dtna (dystrobrevin, alpha [Source:ZFIN;Acc:ZDB-GENE-070117-2]) HSP 1 Score: 318.161 bits (814), Expect = 2.217e-94 Identity = 219/632 (34.65%), Postives = 334/632 (52.85%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTS---SSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQ-----FRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVL------NTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGV 2083
MA ++L EM+A + DSIR + YR ACKLR++Q+R L L+D+ V+E+FR+ GL M+ + ++E +++ ++ QL+ R+P Q++ + +SI +L+ +LL +YD G G++SV +K+AL+TL GK +DK +Y F+ + DP G ++ ++F+Q+L ++L L VFEGP+F+Y +K I + K + + FL+ ++DP QCL+WL + HRLAN+ENV H V C C + ++GFRY+CQ+CH+Y LCQ+CFW G +G+HSN H +KEYTS +K S +L + R+ + + R V N M S PY SR+ A D+ + RA+P+ + + V +S I + G + + L+ + DDEH LIARYAS L + ++ S+ D K Q+ LIA+LE KN+EIL EIQRLR + + A +TDK NP LL EL+ LR RK+ELE RM++LQESR ELM QLE LM +L ++ SS ++A S + + + +T + S Q L G+
Sbjct: 10 MADKRQLFAEMRALELDSIRLSTYRAACKLRFVQKRCNLHLVDIWNVIEAFRENGLNTMDLNTEFTVARLEAILSTIFHQLNKRMPTTHQIN---VEQSILLLLNFLLAAYDPDGQGKVSVFVVKMALATLCGGKILDKLRYIFSQIADPDGIMVYSQFDQFLKEVLKLPGVVFEGPSFSYTEHTAK-ICFSQHKQVTLNIFLDAFMSDPPAQCLVWLPLMHRLANVENVFHPVECSYCQSQSMMGFRYRCQQCHNYQLCQECFWRGNASGSHSNQHQMKEYTSWKSPAKKLSNALSKSLSCASSREPLHPLFSDTPEKPLNLAHVVPPRPVTNGNEFMSC-YSMPSTSNPYS---SRVAANDSVKPRKPLARAAPD---LLKGKGVQYS----IDIADRLADEHVLIGLYANLLQKKRSCLLENSSNNQDDEHYLIARYASRLAADEASAKSRAPEAMSLPLDTN----------------------KQQRLLIAELENKNREILLEIQRLRQQ---HVEASQPSTDKEQ------------QNPTLLAELKQLRQRKEELEQRMSALQESRRELMVQLEQLMLLLKNPGAGSSPRSSPGHTASSSVPTPVLLTSCSTTPSHSPQDSLMGL 589
BLAST of Dystrobrevin vs. Ensembl Cavefish
Match: dtnbb (dystrobrevin, beta b [Source:ZFIN;Acc:ZDB-GENE-070117-3]) HSP 1 Score: 282.337 bits (721), Expect = 1.706e-82 Identity = 124/296 (41.89%), Postives = 202/296 (68.24%), Query Frame = 2
Query: 242 KRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
++L EM+A+ FD IR + YRTACKLR++Q+R L L+DV ++E+FR GL ++ + ++ +++E +++ ++ QL+ RLP Q++ + +SI +L+ +++ +YD+ G G+L+V ++K L+T+ GK +DK +Y F+ ++D G ++ +F+Q+L ++L L VFEGP+F Y + + + K I++ FL+ M+ADP PQCL+WL + HRLAN+ENV H V C C E ++GFRY+CQ+CH Y LCQ+CFW G +G HSN H +KE+ SS KS +++ HA+ KS
Sbjct: 16 RQLFMEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDVWNMIEAFRDNGLSTLDHNAEINVSRLETILSSIFYQLNKRLPTTHQIN---VEQSIGLLLNFMVATYDSEGHGKLTVFSMKSMLATMCGGKIVDKLRYIFSQISDSGGTMVFAKFDQFLREVLKLPTAVFEGPSFGYTEHSVR-TCFPQQKKILLNTFLDVMMADPPPQCLVWLPLMHRLANVENVFHPVECSYCRSESMMGFRYRCQQCHGYQLCQNCFWRGHASGPHSNQHQMKEH-SSWKSPAKKLSHAISKS 306 HSP 2 Score: 83.9593 bits (206), Expect = 4.154e-16 Identity = 79/201 (39.30%), Postives = 106/201 (52.74%), Query Frame = 2
Query: 1496 DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
D+EHRLIARYA+ L + S ++T P ++ D + K Q++LIA+LE KN+EIL+EIQRLRLE + A +K NP LL ELR LRHRKDELE RM++LQESR ELM QLE LMR+L + +S+ + S +M + +A + T + Q L GV
Sbjct: 344 DEEHRLIARYAARLAAEAS--------------NSTQCPPTDLSFNFD--------ANKQQRQLIAELENKNREILQEIQRLRLE---HEQASQPTPEKAQ------------QNPTLLAELRLLRHRKDELEKRMSALQESRRELMVQLEGLMRLLKAQTGGSPHSSPSHSASCTMPMPIRSTSAGSTPTHTPQDCLAGV 507
BLAST of Dystrobrevin vs. Ensembl Cavefish
Match: dtna (dystrobrevin, alpha [Source:ZFIN;Acc:ZDB-GENE-070117-2]) HSP 1 Score: 276.559 bits (706), Expect = 4.438e-81 Identity = 128/300 (42.67%), Postives = 203/300 (67.67%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A + DSIR + YR ACKLR++Q+R L L+D+ V+E+FR+ GL M+ + ++E +++ ++ QL+ R+P Q++ + +SI +L+ +LL +YD G G++SV +K+AL+TL GK +DK +Y F+ + DP G ++ ++F+Q+L ++L L VFEGP+F+Y +K I + K + + FL+ ++DP QCL+WL + HRLAN+ENV H V C C + ++GFRY+CQ+CH+Y LCQ+CFW G +G+HSN H +KEYT S KS +++ +AL KS
Sbjct: 10 MADKRQLFAEMRALELDSIRLSTYRAACKLRFVQKRCNLHLVDIWNVIEAFRENGLNTMDLNTEFTVARLEAILSTIFHQLNKRMPTTHQIN---VEQSILLLLNFLLAAYDPDGQGKVSVFVVKMALATLCGGKILDKLRYIFSQIADPDGIMVYSQFDQFLKEVLKLPGVVFEGPSFSYTEHTAK-ICFSQHKQVTLNIFLDAFMSDPPAQCLVWLPLMHRLANVENVFHPVECSYCQSQSMMGFRYRCQQCHNYQLCQECFWRGNASGSHSNQHQMKEYT-SWKSPAKKLSNALSKS 304 HSP 2 Score: 65.4698 bits (158), Expect = 2.414e-10 Identity = 60/144 (41.67%), Postives = 81/144 (56.25%), Query Frame = 2
Query: 1670 KSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVL------NTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGV 2083
K Q+ LIA+LE KN+EIL EIQRLR + + A +TDK NP LL EL+ LR RK+ELE RM++LQESR ELM QLE LM +L ++ SS ++A S + + + +T + S Q L G+
Sbjct: 346 KQQRLLIAELENKNREILLEIQRLRQQ---HVEASQPSTDKEQ------------QNPTLLAELKQLRQRKEELEQRMSALQESRRELMVQLEQLMLLLKNPGAGSSPRSSPGHTASSSVPTPVLLTSCSTTPSHSPQDSLMGL 474
BLAST of Dystrobrevin vs. Ensembl Cavefish
Match: drp2 (dystrophin related protein 2 [Source:NCBI gene;Acc:103025899]) HSP 1 Score: 138.272 bits (347), Expect = 9.604e-33 Identity = 105/356 (29.49%), Postives = 170/356 (47.75%), Query Frame = 2
Query: 275 FDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFR----QTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLA-----VGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEY--TSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQ---ASPCLPYRNTVSRIQ 1300
++I+F+AYRTA KLR +Q+ RL L+ + V + FR Q G Y+M+ +E++ A T L RL + N IP ++M + WLL YD+ G++ V++ K + +L + +K++Y F + P+G LH+++ + V F G N S S F + AI + FLE M +P Q ++WL + HR+ E+ +H RC C + I GFRY+ + + ++CQ CF TG TT + + EY ++S R F L+ + SK Y Q R Q +++ +G+ +SP LP+ +T SRI+
Sbjct: 317 LNNIKFSAYRTAMKLRRVQKALRLDLLKLTSVTDVFREQELQHGEYVMDV--------VEVIHA--LTALYERLEEERSVLIN-IPLCVDMCLNWLLNVYDSGRNGKMRVLSFKTGVVSLCNADVQEKYRYLFRQVCGPNGLTDQKHLSLLLHEVIQIPRQLGEVAAFGGSNVE-PSVRSCFRMAPGKPAIEVSHFLEWMSLEP--QSVVWLPVLHRVTAAESAKHQARCYICKQCPIKGFRYRSLKQFNVDICQMCFLTGRTTKGKRLHYPIMEYYTPTTSGEKMRDFAKTLKNKF-------------RSKQYFSKHPQ-RGYLPVQTVLEAESGETPCSSPRLPHADTHSRIE 644
BLAST of Dystrobrevin vs. Ensembl Sea Lamprey
Match: dtnba (dystrobrevin, beta a [Source:ZFIN;Acc:ZDB-GENE-030131-3967]) HSP 1 Score: 304.294 bits (778), Expect = 2.271e-90 Identity = 131/300 (43.67%), Postives = 205/300 (68.33%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ FD+IR + YRTACKLR++Q++ L L+D+ ++E+FR+ GL +++ + ++E +IA +Y QL+ RLP Q+H + +SI +L+ ++L +Y+ G G+++V +KVAL+T+ GK +DK +Y F+ ++D +G ++ +F+QYLH++L L VFEGP+F Y QA++ + K + + FL+ +++DP PQ L+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH Y LCQDCFW G + HSN H +KEYT S KS +++ AL KS
Sbjct: 12 MADRRQLFLEMRAQNFDAIRLSTYRTACKLRFVQKKCNLHLVDIWNMIEAFRENGLNALDAGAEVSVARLENLIASVYYQLNKRLPTTHQIH---VEQSINLLLNFMLAAYNGEGCGKMTVFGVKVALATMCGGKVVDKLRYIFSQISDSNGVMVLNKFDQYLHEVLKLPTAVFEGPSFGYTEQAARSCFPHQQKKVTLNVFLDALMSDPPPQILIWLPLMHRLANVENVFHPVECSFCHSESMLGFRYRCQQCHSYQLCQDCFWRGQASSTHSNQHQMKEYT-SWKSPAKKLTRALSKS 307 HSP 2 Score: 83.9593 bits (206), Expect = 1.118e-16 Identity = 73/208 (35.10%), Postives = 102/208 (49.04%), Query Frame = 2
Query: 1496 DDEHRLIARYASTLVSSRST--HSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQ-TNSALYSTKSRSMNQ---------AANTISTFSRQSGLTGV 2083
D+EHRLIARYA+ L + ST H+ P E+ SD + K Q++LIA+LE KN+ + + + + + AS + D+ NP LL EL+ LR RKDELE RM++LQESR ELM QLE LM++L Q T S+ S+ S +M + +A + T + Q LTGV
Sbjct: 425 DEEHRLIARYAARLAAEASTTVHTVHRTP-------------TELAFNSD--------TNKQQRQLIAELENKNR-EIMQEIQRLRLEHEQASQTSPEKDQ--------------QNPTLLAELKLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEEQKQATQSSPRSSPSHTMARPMPMPIRSTSAGSTPTHTPQDSLTGV 596
BLAST of Dystrobrevin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002801.1 (pep scaffold:Pmarinus_7.0:GL476499:231780:258689:1 gene:ENSPMAG00000002555.1 transcript:ENSPMAT00000002801.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 130.568 bits (327), Expect = 1.517e-33 Identity = 83/282 (29.43%), Postives = 142/282 (50.35%), Query Frame = 2
Query: 275 FDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLI--PESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLA-----VGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHS 1099
+++RF+AYRTA KLR +Q+ L L+ + + F Q+GL ++ +D ++ + +Y L + H +L+ P ++M + WLL YDT G++ ++ K L +L++ DK+++ F + SG R LHD + + V F G N + ++ GR + I FLE M +P Q ++WL + HR+A E +H +C C I+GFRY+ + +Y++CQ CF++G T H ++ + EY + SHS
Sbjct: 30 LNNVRFSAYRTAMKLRRLQKALCLDLVSLDALTNVFEQSGL--KQNDRLMDVSEAVGCLTTIYQGLERK-------HSDLVNLPLCVDMCLNWLLNVYDTGRGGKIRELSFKTGLVSLSNAHLEDKYRFLFKQVASVSGLCDQRRLGLMLHDAVQIPRQLGEVASFGGSNIEPSVRSCFQFANGRPE-IEATMFLEWMRMEP--QSMVWLPVLHRVAASETAKHQAKCNICKECPIVGFRYRSLKHFNYDVCQSCFFSGRTAKGHKLSYPMVEYCTPVSSHS 299
BLAST of Dystrobrevin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004878.1 (pep scaffold:Pmarinus_7.0:GL480232:9823:26212:1 gene:ENSPMAG00000004410.1 transcript:ENSPMAT00000004878.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 110.538 bits (275), Expect = 1.034e-26 Identity = 86/290 (29.66%), Postives = 132/290 (45.52%), Query Frame = 2
Query: 275 FDSIRFAAYRTACKLRYIQQ---RTR-----------LILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFK-YHFTLLTDPSGALIPTR-FEQYLHDLLVLA-----VGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTS 1081
+S+RF+AYRTA KLR +Q+ RTR L D + + R G T++ ++A+LY L + G P +M + WLL YD S TG++ ++LKV L L+ +K+K Y F ++ P G R L + + + V F G N S S F + + FLE M +P Q L+WL + HR+A E +H +C C I+GFRY+ + +Y++CQ CF++G T H + + EY +
Sbjct: 28 LNSVRFSAYRTAMKLRRLQKALCRTRHQPEMSTIPMGLDCHDEQSMSPHERLVG-----------ATEVGRLLAELYGGLES----GQGQRLVAAPLCTDMALNWLLNVYDPSRTGKIRSLSLKVGLICLSKAPLEEKYKLYIFRQVSGPGGGGCDQRQLGLLLQEAIQIPRQLGEVASFGGSNIE-PSVRSCFKFANSRDMVEVGRFLEWMKLEP--QSLVWLPVLHRVAASETAKHQAKCNICKECPIVGFRYRSLKHFNYDICQSCFFSGRTAKGHKLHYPMVEYCT 299
BLAST of Dystrobrevin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010595.1 (pep scaffold:Pmarinus_7.0:GL477281:35182:38646:-1 gene:ENSPMAG00000009594.1 transcript:ENSPMAT00000010595.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 88.1965 bits (217), Expect = 3.197e-19 Identity = 78/291 (26.80%), Postives = 134/291 (46.05%), Query Frame = 2
Query: 248 LINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPE-SIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFT------LLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRS-----KAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSS 1084
L+ + +Q + IR+A YRTA KL +Q+ L L+ V ++ F + ++ L+ Q+ ++ +++ S P P++ E + E+ + LL D+ +G++S ++ AL L++G+ K++ +L + IP Y LL L + EG F A + S +I +FL L++P Q LWL +R+ H +C C I+G R++C RC + +LCQ+CF TG TG H+ +H V E +S
Sbjct: 4 LLRLVLTEQLNVIRYAVYRTAAKLLALQKLCCLHLVSVSTILTVFNSSA---VDWESELNVRQVYQLLRKVHGMASREQPM-----PHVDGELASELTLNLLLAICDSERSGKVSPRSMWNALLLLSTGQLTHKYRGGVVCLCFARILPHCNAIGIPCN-NIYASQLLAL---LGEGCAFGTAEMAVTSLFHAVSYHSDIPSITESQFLGWCLSEP--QLFLWLPAMYRMMKAAGSIHEAKCNICKTCPIVGLRFRCLRCWNLDLCQNCFLTGRDTGWHAPSHPVIESCTS 280
BLAST of Dystrobrevin vs. Ensembl Nematostella
Match: EDO47831 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKW6]) HSP 1 Score: 280.796 bits (717), Expect = 2.969e-82 Identity = 201/662 (30.36%), Postives = 320/662 (48.34%), Query Frame = 2
Query: 275 FDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFIL-----VGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSK----DYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYH---------DDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSLLPSNSGQPLKLHG--YGSPMTT---HRSLSYTADS 2191
FD+IRFA+YRTA KL++IQ++T L L+DV ++E+FR+ GL ++ + L ++E +++ ++ L+ RLP + + SI ++ WLLY+YD+ GR+ V+++K ALS++ G+ +DK +YHF+ + D +G L +FE YL +LL L V E P F + + + R + ++ FLE ++ P WL+ ++ N H V C+ C + ++GFRYKC C++Y LCQDCFW G + +H HD++EY++ + G +LR + + +GK + D+ + SR +D + P+ + P N S + SP+ + ++ + N + +S C N++ +G W W + + DDEH+LI+RYA+ LV T S P TS S+ + DA K Q+ELI LE KN+ +L + D+ + A + S + NP LL EL+ LR RKDELE RM++LQESR ELM QLE LM +L + S + ++ + + A+T Q+ T ++P SS L G + G GSP T + L ADS
Sbjct: 3 FDTIRFASYRTAAKLQFIQKKTNLHLVDVYNMIEAFRENGLNTLDHNTELHELRLEAIVSSIFYALNKRLPTTHNVD---VERSISLVTNWLLYAYDSDAIGRIRVLSVKTALSSMCYGRLVDKLRYHFSQIEDNNGMLNFPKFEAYLRELLQLPASVGEAPTFGFTEDVASIFFKPQGPLDRQRTQLVH-FLECVMNKEPPPPYAWLSTLQKMNNAAKTEHQVACQVCKNKPVVGFRYKCLHCYNYVLCQDCFWRGKVSQHHKTDHDMREYSTWNAGEK---GSSLRSKF-------LCGSGKKKRPSLPDFPREPEPSRTLDMTNIVPPLPSDLSGP----NNATS--------DYVTSPSPESVVSNVSSNPTKLSD----EVTCVNLS-SGFW------------CWIFYLYYLILFSCRMDDEHKLISRYAARLVRVHKTFS----PATSSSELSIDA-------------------NKEQRELIQTLENKNRLLL--------------KEIRRLRDEHDEA--SKSAAQLAQNPELLAELKLLRQRKDELELRMSALQESRRELMVQLEGLMNLLKVIARSPKAQHIAASPAPGLFSKAST-----PQTPGTPMSPDSSKLSGVDGDIKQAFGDQAGSPSLTRNLRQDLLLAADS 577
BLAST of Dystrobrevin vs. Ensembl Nematostella
Match: EDO41097 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5C8]) HSP 1 Score: 159.458 bits (402), Expect = 8.322e-40 Identity = 150/585 (25.64%), Postives = 247/585 (42.22%), Query Frame = 2
Query: 272 QFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVL-----AVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYST 2011
+ + I+++AYRTA KLR IQ+ T+L L+ + + +F Q L + N + M+ L+T N D ++P + +I++ + WLL YD+ G++ +++ K+ L L DK+ Y F L+ D G + + LHD L + + F G N S S F + I +F+ + A+P Q ++WL HRLA E V+H +C C I+GFR++C +C +Y+LCQ CFW+G + H TH V +Y S+ S G+ KD+ S RN ++ K P + LP + + + G A P+ MT QNVN +++ + + + G K++ +P D+EH+LIA+Y +L + +S D + +E I KLE +N+ Q + + D +S+ + S + LL E + LR K LE RM L++ +L QL+ L ++L+ +T S Y T
Sbjct: 351 ELNDIKYSAYRTAMKLRCIQKATKLDLVTLNNLSSAFVQHNL---SKARNDALIGVAEMVDTLHTVFDNIEVGFDNVNPAI---NIDLTLNWLLNVYDSGRVGKIRLLSFKIGLVCLCRAHLDDKYNYLFKLVADNDGKMDHKQLGLLLHDSLQVPRQLGEIAAFGGSNIE-PSVRSCFEKAREKERIDPTQFVYWLSAEP--QSIVWLPTLHRLAASEAVKHKAKCSICKEYPIVGFRFRCLKCFNYDLCQSCFWSGRISHEHRLTHPVHQYCLSTTS------------------------GEDVKDF---LSMVRNKFKARKYKKNPPKKLG-YLPIQTVM------EGGNLEAPPS---MTPQQNVNNEVHNRLGMFANRLAEAESDGG-----KYSPKPM--------DEEHQLIAQYCQSLKNVCFVSQPRSPTQIVMSLDANEKDDLESE--------------------IGKLEDENR----------YPLQSEYERLKSMRDADHSSDGDLSTGSQSRDTELLTEAKLLRQHKGRLEARMQVLEDHNRQLEAQLQRLRQLLD---QVRTGSLWYHT 843
BLAST of Dystrobrevin vs. Ensembl Nematostella
Match: EDO45067 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTQ0]) HSP 1 Score: 139.043 bits (349), Expect = 5.109e-36 Identity = 87/304 (28.62%), Postives = 148/304 (48.68%), Query Frame = 2
Query: 272 QFDSIRFAAYRTACKLRYIQQRTRLILMDV---------RGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASK----FILVGRSKAIVIE-----EFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEY--TSSSKSHSRQFGHALR 1123
+ ++I++AAYRTA KLR I ++T+L L+++ V + + + L + E+S +++ A Q +R D IP + ++ + +L YD TG + ++LK+ +S L + K DK++Y F + + L R +L + L + ++E F+ S F V + + +E F+E M+A+P Q ++WL HRLA E V+H +C C I+GFRY+C +C +++LCQ CFW G + H H +EY S K + F +R
Sbjct: 22 ELNNIKYAAYRTAMKLRAIHKKTQLYLVEIPILTATLDEEDVPDGYTEKALSIPEAS--------KIITALFINQNGDRQDFID------IPMASDLTLNLMLNIYDPGRTGYIQALSLKIGISLLCAAKLQDKYRYLFRQMCNSRAVLDRKRLTLFLQECLQIPKYIYESTIFSGTSVEPAVKNCFETVSFTYTLEVELQKFKSFMEWMVAEP--QTIVWLPTLHRLAVSETVKHEAKCNICKMYPIVGFRYRCLKCFNFDLCQGCFWAGRVSKGHKIGHPTQEYCLAPSQKEDIKDFAKVMR 309
BLAST of Dystrobrevin vs. Ensembl Nematostella
Match: EDO29437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T3M8]) HSP 1 Score: 58.9214 bits (141), Expect = 9.415e-10 Identity = 39/153 (25.49%), Postives = 77/153 (50.33%), Query Frame = 2
Query: 272 QFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLL 730
+ ++I++AAYRTA KLR I ++T+L L+++ + + + + + L + +I L+ + GD+ IP + ++ + +L YD TG + ++LK+ +S L + K DK++Y F + + L R +L + L
Sbjct: 48 ELNNIKYAAYRTAMKLRAIHKKTQLYLVEIPILTATLDEEDVPDGYTEKALSIPEASKIITALFINQN-----GDRQDFIDIPMASDLTLNLMLNIYDPGRTGYIQALSLKIGISLLCAAKLQDKYRYLFRQMCNSRAVLDRKRLTLFLQECL 195
BLAST of Dystrobrevin vs. Ensembl Medaka
Match: dtna (dystrobrevin alpha [Source:NCBI gene;Acc:101173504]) HSP 1 Score: 300.442 bits (768), Expect = 1.601e-88 Identity = 132/300 (44.00%), Postives = 209/300 (69.67%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ DSIR + YRTACKLR++Q++ L L+D+ V+E+FR+ GL M+ + L ++E++++ ++ QL+ RLP Q++ + +SI +L+ +LL +YD G G++ V +K+AL+T+ GK +DK +Y F+ ++D SG ++ ++F+Q+L ++L L + VFEGP+F Y QA++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G +G+HSN H +KEYT S KS +++ H L KS
Sbjct: 12 MADRRQLYVEMRAQDLDSIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEAFRENGLNSMDLNAELSVARLEVVLSTIFYQLNKRLPTTHQIN---VEQSISLLLNFLLAAYDPEGHGKMCVFVVKMALATICGGKILDKLRYIFSQISDSSGIMVHSQFDQFLREVLKLPMAVFEGPSFGYTEQAARACF-AQQKKVSLNTFLDTLMSDPPPQCLVWLPLMHRLANVENVFHPVECSYCHTESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYT-SWKSPAKKLTHVLSKS 306 HSP 2 Score: 78.5666 bits (192), Expect = 2.272e-14 Identity = 75/196 (38.27%), Postives = 97/196 (49.49%), Query Frame = 2
Query: 1568 DMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSA-------------------KSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
DMP ++ + P+ LF+ +MPTS K QK+LIA+LE+KN+EIL+EIQRLR++ + A DK NP LL ELR LR RKDELE RM++LQESR ELM QLE LM +L T S+ T SR + + +A T T + Q L GV
Sbjct: 322 DMPEKPLNLAHIVPPRPVNIANEYLFSHSMPTSGNPYSTKKVPMDLPCSLDANKQQKQLIAELESKNREILQEIQRLRIQ---HEEASQPPPDKGQ------------QNPTLLAELRLLRQRKDELEQRMSTLQESRRELMVQLEQLMMLLKTQGPGSPRSSPSHTISRPIPTPIHSDSAGTTPTHTPQDSLMGV 502
BLAST of Dystrobrevin vs. Ensembl Medaka
Match: dtna (dystrobrevin alpha [Source:NCBI gene;Acc:101173504]) HSP 1 Score: 301.212 bits (770), Expect = 2.910e-88 Identity = 132/300 (44.00%), Postives = 209/300 (69.67%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ DSIR + YRTACKLR++Q++ L L+D+ V+E+FR+ GL M+ + L ++E++++ ++ QL+ RLP Q++ + +SI +L+ +LL +YD G G++ V +K+AL+T+ GK +DK +Y F+ ++D SG ++ ++F+Q+L ++L L + VFEGP+F Y QA++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G +G+HSN H +KEYT S KS +++ H L KS
Sbjct: 18 MADRRQLYVEMRAQDLDSIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEAFRENGLNSMDLNAELSVARLEVVLSTIFYQLNKRLPTTHQIN---VEQSISLLLNFLLAAYDPEGHGKMCVFVVKMALATICGGKILDKLRYIFSQISDSSGIMVHSQFDQFLREVLKLPMAVFEGPSFGYTEQAARACF-AQQKKVSLNTFLDTLMSDPPPQCLVWLPLMHRLANVENVFHPVECSYCHTESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYT-SWKSPAKKLTHVLSKS 312 HSP 2 Score: 69.3218 bits (168), Expect = 2.027e-11 Identity = 80/214 (37.38%), Postives = 103/214 (48.13%), Query Frame = 2
Query: 1490 YHDDEHRLIARYASTLVSSRSTHS---GLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLN--------TSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
+ D+EH LIARYA+ L S + +D+P + DA K QK+LIA+LE+KN+EIL+EIQRLR++ + A DK NP LL ELR LR RKDELE RM++LQESR ELM QLE LM +L T S+ T SR + + +A T T + Q L GV
Sbjct: 376 HQDEEHSLIARYAARLASDAAAQQQRVPMDLPCS------LDA-------------------NKQQKQLIAELESKNREILQEIQRLRIQ---HEEASQPPPDKGQ------------QNPTLLAELRLLRQRKDELEQRMSTLQESRRELMVQLEQLMMLLKLEEEQKRATQGPGSPRSSPSHTISRPIPTPIHSDSAGTTPTHTPQDSLMGV 549
BLAST of Dystrobrevin vs. Ensembl Medaka
Match: dtna (dystrobrevin alpha [Source:NCBI gene;Acc:101173504]) HSP 1 Score: 300.827 bits (769), Expect = 8.136e-88 Identity = 132/300 (44.00%), Postives = 209/300 (69.67%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ DSIR + YRTACKLR++Q++ L L+D+ V+E+FR+ GL M+ + L ++E++++ ++ QL+ RLP Q++ + +SI +L+ +LL +YD G G++ V +K+AL+T+ GK +DK +Y F+ ++D SG ++ ++F+Q+L ++L L + VFEGP+F Y QA++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G +G+HSN H +KEYT S KS +++ H L KS
Sbjct: 18 MADRRQLYVEMRAQDLDSIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEAFRENGLNSMDLNAELSVARLEVVLSTIFYQLNKRLPTTHQIN---VEQSISLLLNFLLAAYDPEGHGKMCVFVVKMALATICGGKILDKLRYIFSQISDSSGIMVHSQFDQFLREVLKLPMAVFEGPSFGYTEQAARACF-AQQKKVSLNTFLDTLMSDPPPQCLVWLPLMHRLANVENVFHPVECSYCHTESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYT-SWKSPAKKLTHVLSKS 312 HSP 2 Score: 68.9366 bits (167), Expect = 2.488e-11 Identity = 80/214 (37.38%), Postives = 103/214 (48.13%), Query Frame = 2
Query: 1490 YHDDEHRLIARYASTLVSSRSTHS---GLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLN--------TSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
+ D+EH LIARYA+ L S + +D+P + DA K QK+LIA+LE+KN+EIL+EIQRLR++ + A DK NP LL ELR LR RKDELE RM++LQESR ELM QLE LM +L T S+ T SR + + +A T T + Q L GV
Sbjct: 408 HQDEEHSLIARYAARLASDAAAQQQRVPMDLPCS------LDA-------------------NKQQKQLIAELESKNREILQEIQRLRIQ---HEEASQPPPDKGQ------------QNPTLLAELRLLRQRKDELEQRMSTLQESRRELMVQLEQLMMLLKLEEEQKRATQGPGSPRSSPSHTISRPIPTPIHSDSAGTTPTHTPQDSLMGV 581
BLAST of Dystrobrevin vs. Ensembl Medaka
Match: dtna (dystrobrevin alpha [Source:NCBI gene;Acc:101173504]) HSP 1 Score: 301.212 bits (770), Expect = 8.309e-88 Identity = 132/300 (44.00%), Postives = 209/300 (69.67%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ DSIR + YRTACKLR++Q++ L L+D+ V+E+FR+ GL M+ + L ++E++++ ++ QL+ RLP Q++ + +SI +L+ +LL +YD G G++ V +K+AL+T+ GK +DK +Y F+ ++D SG ++ ++F+Q+L ++L L + VFEGP+F Y QA++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G +G+HSN H +KEYT S KS +++ H L KS
Sbjct: 12 MADRRQLYVEMRAQDLDSIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEAFRENGLNSMDLNAELSVARLEVVLSTIFYQLNKRLPTTHQIN---VEQSISLLLNFLLAAYDPEGHGKMCVFVVKMALATICGGKILDKLRYIFSQISDSSGIMVHSQFDQFLREVLKLPMAVFEGPSFGYTEQAARACF-AQQKKVSLNTFLDTLMSDPPPQCLVWLPLMHRLANVENVFHPVECSYCHTESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYT-SWKSPAKKLTHVLSKS 306 HSP 2 Score: 69.3218 bits (168), Expect = 2.113e-11 Identity = 80/214 (37.38%), Postives = 103/214 (48.13%), Query Frame = 2
Query: 1490 YHDDEHRLIARYASTLVSSRSTHS---GLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLN--------TSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
+ D+EH LIARYA+ L S + +D+P S D + K QK+LIA+LE+KN+EIL+EIQRLR++ + A DK NP LL ELR LR RKDELE RM++LQESR ELM QLE LM +L T S+ T SR + + +A T T + Q L GV
Sbjct: 425 HQDEEHSLIARYAARLASDAAAQQQRVPMDLP---CSLD----------------------ANKQQKQLIAELESKNREILQEIQRLRIQ---HEEASQPPPDKGQ------------QNPTLLAELRLLRQRKDELEQRMSTLQESRRELMVQLEQLMMLLKLEEEQKRATQGPGSPRSSPSHTISRPIPTPIHSDSAGTTPTHTPQDSLMGV 598
BLAST of Dystrobrevin vs. Ensembl Medaka
Match: dtna (dystrobrevin alpha [Source:NCBI gene;Acc:101173504]) HSP 1 Score: 300.827 bits (769), Expect = 1.112e-87 Identity = 132/300 (44.00%), Postives = 209/300 (69.67%), Query Frame = 2
Query: 230 MAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKS 1129
MA ++L EM+A+ DSIR + YRTACKLR++Q++ L L+D+ V+E+FR+ GL M+ + L ++E++++ ++ QL+ RLP Q++ + +SI +L+ +LL +YD G G++ V +K+AL+T+ GK +DK +Y F+ ++D SG ++ ++F+Q+L ++L L + VFEGP+F Y QA++ + K + + FL+ +++DP PQCL+WL + HRLAN+ENV H V C CH E ++GFRY+CQ+CH+Y LCQDCFW G +G+HSN H +KEYT S KS +++ H L KS
Sbjct: 18 MADRRQLYVEMRAQDLDSIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEAFRENGLNSMDLNAELSVARLEVVLSTIFYQLNKRLPTTHQIN---VEQSISLLLNFLLAAYDPEGHGKMCVFVVKMALATICGGKILDKLRYIFSQISDSSGIMVHSQFDQFLREVLKLPMAVFEGPSFGYTEQAARACF-AQQKKVSLNTFLDTLMSDPPPQCLVWLPLMHRLANVENVFHPVECSYCHTESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYT-SWKSPAKKLTHVLSKS 312 HSP 2 Score: 76.6406 bits (187), Expect = 1.157e-13 Identity = 80/206 (38.83%), Postives = 103/206 (50.00%), Query Frame = 2
Query: 1490 YHDDEHRLIARYASTLVSSRSTHS---GLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSM-----NQAANTISTFSRQSGLTGV 2083
+ D+EH LIARYA+ L S + +D+P S D + K QK+LIA+LE+KN+EIL+EIQRLR++ + A DK NP LL ELR LR RKDELE RM++LQESR ELM QLE LM +L T S+ T SR + + +A T T + Q L GV
Sbjct: 431 HQDEEHSLIARYAARLASDAAAQQQRVPMDLP---CSLD----------------------ANKQQKQLIAELESKNREILQEIQRLRIQ---HEEASQPPPDKGQ------------QNPTLLAELRLLRQRKDELEQRMSTLQESRRELMVQLEQLMMLLKTQGPGSPRSSPSHTISRPIPTPIHSDSAGTTPTHTPQDSLMGV 596
BLAST of Dystrobrevin vs. Planmine SMEST
Match: SMESG000078318.1 (SMESG000078318.1) HSP 1 Score: 1576.61 bits (4081), Expect = 0.000e+0 Identity = 771/772 (99.87%), Postives = 772/772 (100.00%), Query Frame = 2
Query: 182 MNTLSKTQNKVTQQIGMAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSLLPSNSGQPLKLHGYGSPMTTHRSLSYTADSNRSVTMGPHSILPQPRFNTLTRHSRTFSADEGLGGFASQPRRTFTSGNRTLESLGVDTTDYYLKQSSDKAKQNNSLSKEMDLRQNLLMAADNVTNAMTGLVR 2497
MNTLSKTQNKVTQQIGMAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKEILREIQRLRLEQQQNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSLLPSNSGQPLKLHGYGSPMTTHRSLSYTADSNRSVTMGPHSILPQPRFNTLTRHSRTFSADEGLGGFASQPRRTFTSGNRTLESLGVDTTDYYLKQSSDKAKQNNSLSKEMDLRQNLLMAADNVTNAMTGLV+
Sbjct: 1 MNTLSKTQNKVTQQIGMAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKEILREIQRLRLEQQQNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSLLPSNSGQPLKLHGYGSPMTTHRSLSYTADSNRSVTMGPHSILPQPRFNTLTRHSRTFSADEGLGGFASQPRRTFTSGNRTLESLGVDTTDYYLKQSSDKAKQNNSLSKEMDLRQNLLMAADNVTNAMTGLVK 772 HSP 2 Score: 337.421 bits (864), Expect = 4.865e-108 Identity = 187/188 (99.47%), Postives = 187/188 (99.47%), Query Frame = 3
Query: 2652 GKKSSTAPQNLNSATVFANSRISSRILSEQRFLNELRARRQNNTLGRGSNDQNDYNNHNLQNDSPPGPAPKLQESSVNKGVRIAXXXXXXHRTRPQGELRTNSNGTLCNYGESDSEAYLYSDPECSLLRLNEDEMGPAMSLGRGREKSIPMENEKLYDIHSLHQKIXXXXXXXXXXXXXXRHKWDNSN 3215
KKSSTAPQNLNSATVFANSRISSRILSEQRFLNELRARRQNNTLGRGSNDQNDYNNHNLQNDSPPGPAPKLQESSVNKGVRIAPPPLPPHRTRPQGELRTNSNGTLCNYGESDSEAYLYSDPECSLLRLNEDEMGPAMSLGRGREKSIPMENEKLYDIHSLHQKINSLNNGDLDQDLDNRHKWDNSN
Sbjct: 825 AKKSSTAPQNLNSATVFANSRISSRILSEQRFLNELRARRQNNTLGRGSNDQNDYNNHNLQNDSPPGPAPKLQESSVNKGVRIAPPPLPPHRTRPQGELRTNSNGTLCNYGESDSEAYLYSDPECSLLRLNEDEMGPAMSLGRGREKSIPMENEKLYDIHSLHQKINSLNNGDLDQDLDNRHKWDNSN 1012 HSP 3 Score: 75.485 bits (184), Expect = 4.865e-108 Identity = 55/56 (98.21%), Postives = 55/56 (98.21%), Query Frame = 1
Query: 2491 CKELQPSANNKXXXXXXXXXXXXXXXXXXXRMNHNYHFNEYESEYERALDDCGMAK 2658
KELQPSANNKQTFSQNSSPTSTSQPNNQNRMNHNYHFNEYESEYERALDDCGMAK
Sbjct: 771 VKELQPSANNKQTFSQNSSPTSTSQPNNQNRMNHNYHFNEYESEYERALDDCGMAK 826
BLAST of Dystrobrevin vs. Planmine SMEST
Match: SMESG000078318.1 (SMESG000078318.1) HSP 1 Score: 1363.21 bits (3527), Expect = 0.000e+0 Identity = 714/835 (85.51%), Postives = 729/835 (87.31%), Query Frame = 2
Query: 182 MNTLSKTQNKVTQQIGMAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHAL----------------RKSWDRQNN--------------STVACTGKSSKDYQQNQSQSRNVDN-------NQRMMKTPAG-----QASPCLPYRNTVSRIQA-------ADNGQFRASPNQTMMTT------DQN--------VNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKXXXXXXXXXXXXXXXNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSLLPSNSGQPLKLHGYGSPMTTHRSLSYTADSNRSVTMGPHSILPQPRFNTLTRHSRTFSADEGLGGFASQPRRTFTSGNRTLESLGVDTTDYYLKQSSDKAKQNNSLSKEMDLRQNLLMAADNVTNAMTGLVR 2497
MNTLSKTQNKVTQQIGMAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHAL + S D Q N T A Y+ S+ + DN NQ MM T + + L + + + A A N +S +Q ++ T D+N VNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKEILREIQRLRLEQQQNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSLLPSNSGQPLKLHGYGSPMTTHRSLSYTADSNRSVTMGPHSILPQPRFNTLTRHSRTFSADEGLGGFASQPRRTFTSGNRTLESLGVDTTDYYLKQSSDKAKQNNSLSKEMDLRQNLLMAADNVTNAMTGLV+
Sbjct: 1 MNTLSKTQNKVTQQIGMAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQQRTRLILMDVRGVVESFRQTGLYLMESSCNLDRTQIEMMIAQLYTQLSNRLPAGDQLHPNLIPESIEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILVGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEYTSSSKSHSRQFGHALRKSWDRQNNSTVACTGKSSKDYQQNQSQSRNVDNNQRMMKTPAGQASPCLPYRNTVSRIQAADNGQFRASPNQTMMTTDQNFTGNEKWNKMLLFSHQQHSLDASTKTLNDASNAGLMSSNSQPLIMTQAVNKIDRNFNTASPSSVNFSGVSQIPSMNHACSNVTNTGNWDSSLKHTNQPSKDWRQFYHDDEHRLIARYASTLVSSRSTHSGLDMPHTSISQDNTDAPKIEVHLRSDLFNQNMPTSAKSQKELIAKLEAKNKEILREIQRLRLEQQQNASAVNAATDKTNSAINNDSVTGIVNNPNLLVELRNLRHRKDELENRMTSLQESRLELMQQLESLMRVLNTSSSSQTNSALYSTKSRSMNQAANTISTFSRQSGLTGVTPLSSLLPSNSGQPLKLHGYGSPMTTHRSLSYTADSNRSVTMGPHSILPQPRFNTLTRHSRTFSADEGLGGFASQPRRTFTSGNRTLESLGVDTTDYYLKQSSDKAKQNNSLSKEMDLRQNLLMAADNVTNAMTGLVK 835 HSP 2 Score: 337.806 bits (865), Expect = 3.291e-108 Identity = 187/188 (99.47%), Postives = 187/188 (99.47%), Query Frame = 3
Query: 2652 GKKSSTAPQNLNSATVFANSRISSRILSEQRFLNELRARRQNNTLGRGSNDQNDYNNHNLQNDSPPGPAPKLQESSVNKGVRIAXXXXXXHRTRPQGELRTNSNGTLCNYGESDSEAYLYSDPECSLLRLNEDEMGPAMSLGRGREKSIPMENEKLYDIHSLHQKIXXXXXXXXXXXXXXRHKWDNSN 3215
KKSSTAPQNLNSATVFANSRISSRILSEQRFLNELRARRQNNTLGRGSNDQNDYNNHNLQNDSPPGPAPKLQESSVNKGVRIAPPPLPPHRTRPQGELRTNSNGTLCNYGESDSEAYLYSDPECSLLRLNEDEMGPAMSLGRGREKSIPMENEKLYDIHSLHQKINSLNNGDLDQDLDNRHKWDNSN
Sbjct: 888 AKKSSTAPQNLNSATVFANSRISSRILSEQRFLNELRARRQNNTLGRGSNDQNDYNNHNLQNDSPPGPAPKLQESSVNKGVRIAPPPLPPHRTRPQGELRTNSNGTLCNYGESDSEAYLYSDPECSLLRLNEDEMGPAMSLGRGREKSIPMENEKLYDIHSLHQKINSLNNGDLDQDLDNRHKWDNSN 1075 HSP 3 Score: 75.8702 bits (185), Expect = 3.291e-108 Identity = 55/56 (98.21%), Postives = 55/56 (98.21%), Query Frame = 1
Query: 2491 CKELQPSANNKXXXXXXXXXXXXXXXXXXXRMNHNYHFNEYESEYERALDDCGMAK 2658
KELQPSANNKQTFSQNSSPTSTSQPNNQNRMNHNYHFNEYESEYERALDDCGMAK
Sbjct: 834 VKELQPSANNKQTFSQNSSPTSTSQPNNQNRMNHNYHFNEYESEYERALDDCGMAK 889
BLAST of Dystrobrevin vs. Planmine SMEST
Match: SMESG000020523.1 (SMESG000020523.1) HSP 1 Score: 116.316 bits (290), Expect = 1.222e-25 Identity = 59/208 (28.37%), Postives = 110/208 (52.88%), Query Frame = 2
Query: 527 IEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFAYNSQASKFILV-------GRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEY--TSSSKSHSRQFGHALR 1123
+++ + WLL YD++ G++ V++LK A+ L + +K+KY F+L+ + G L R L D +++ + E +F ++ I G + I + FL + +P Q L+WL + +R+ + E+ H +C C + I+G RY+C RC +++LCQ CF+ T+ +H +H ++EY +SS+ + R + R
Sbjct: 3366 VDLALNWLLNVYDSARNGKIRVLSLKTAIVILTNASLDEKYKYLFSLVCNNQGQLDSPRLTAILTDCVLIPKHLNESSSFGADNVKPSVISCFKNSPESGNHRFIRLSNFLAWLRLEP--QSLVWLPVLNRIISAESAVHQAKCGVCKIQPIVGLRYRCLRCLNFDLCQACFFYSKTSKSHKVSHPMQEYCNVTSSRENFRDYSRIFR 3571
BLAST of Dystrobrevin vs. Planmine SMEST
Match: SMESG000020523.1 (SMESG000020523.1) HSP 1 Score: 103.219 bits (256), Expect = 9.964e-22 Identity = 60/246 (24.39%), Postives = 112/246 (45.53%), Query Frame = 2
Query: 527 IEMLMGWLLYSYDTSGTGRLSVMALKVALSTLASGKPMDKFKYHFTLLTDPSGALIPTRFEQYLHDLLVLAVGVFEGPNFA-----------YNSQASKFIL----------------------------------VGRSKAIVIEEFLEKMLADPGPQCLLWLTIFHRLANIENVRHNVRCEGCHREVIIGFRYKCQRCHHYNLCQDCFWTGVTTGNHSNTHDVKEY--TSSSKSHSRQFGHALR 1123
+++ + WLL YD++ G++ V++LK A+ L + +K+KY F+L+ + G L R L D +++ + E +F + + KF+ G + I + FL + +P Q L+WL + +R+ + E+ H +C C + I+G RY+C RC +++LCQ CF+ T+ +H +H ++EY +SS+ + R + R
Sbjct: 3358 VDLALNWLLNVYDSARNGKIRVLSLKTAIVILTNASLDEKYKYLFSLVCNNQGQLDSPRLTAILTDCVLIPKHLNESSSFGADNVKPSVISCFKNVDDKFVEKSFDKKDTTFQRIRASFRRKKNSNSENSNEKSPESGNHRFIRLSNFLAWLRLEP--QSLVWLPVLNRIISAESAVHQAKCGVCKIQPIVGLRYRCLRCLNFDLCQACFFYSKTSKSHKVSHPMQEYCNVTSSRENFRDYSRIFR 3601 The following BLAST results are available for this feature:
BLAST of Dystrobrevin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Dystrobrevin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Dystrobrevin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Dystrobrevin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Dystrobrevin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Dystrobrevin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Dystrobrevin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Dystrobrevin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Dystrobrevin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Dystrobrevin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of Dystrobrevin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Dystrobrevin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Dystrobrevin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Dystrobrevin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 4
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30007670 ID=SMED30007670|Name=Dystrobrevin|organism=Schmidtea mediterranea sexual|type=transcript|length=3681bpback to top protein sequence of SMED30007670-orf-1 >SMED30007670-orf-1 ID=SMED30007670-orf-1|Name=SMED30007670-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=802bp MNTLSKTQNKVTQQIGMAGFKRLINEMKAKQFDSIRFAAYRTACKLRYIQback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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