One cut domain family member

Overview


Name	One cut domain family member
Smed ID	SMED30007624
Length (bp)	2671

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of One cut domain family member (SMED30007624) t-SNE clustered cells

Violin plots show distribution of expression levels for One cut domain family member (SMED30007624) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30007624

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
prepharyngeal region	SMED30007624	h1SMcG0005292	SmedASXL_018621	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
prepharyngeal region	SMED30007624	h1SMcG0005292	SmedASXL_004526	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
prepharyngeal region	SMED30007624	h1SMcG0005292	SmedASXL_002262	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016

Note: Hover over icons to view figure legend

Homology

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BLAST of One cut domain family member vs. Ensembl Human
Match: ONECUT1 (one cut homeobox 1 [Source:HGNC Symbol;Acc:HGNC:8138])

HSP 1 Score: 263.848 bits (673), Expect = 1.750e-78
Identity = 127/164 (77.44%), Postives = 144/164 (87.80%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE E  K +   P KK RLVFT++QRRTL AIF+E KRPSK +Q TI+QQLGL +STV+NFFMNARRRS+DKWQDE
Sbjct:  288 QMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEHGKDRGNTP-KKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDE 447

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BLAST of One cut domain family member vs. Ensembl Human
Match: ONECUT3 (one cut homeobox 3 [Source:NCBI gene;Acc:390874])

HSP 1 Score: 259.225 bits (661), Expect = 2.207e-76
Identity = 124/162 (76.54%), Postives = 145/162 (89.51%), Query Frame = 1

Query: 1006 DEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            +EINT+E++QRI++ELKRYSIPQAIFAQRIL RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE EQ K + ++P KKQRLVFT++QRRTL+AIF+E KRPSK MQ TI+QQLGL ++TV+NFFMNARRR +++W +E
Sbjct:  319 EEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEQQKERALQP-KKQRLVFTDLQRRTLIAIFKENKRPSKEMQVTISQQLGLELNTVSNFFMNARRRCMNRWAEE 476

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BLAST of One cut domain family member vs. Ensembl Human
Match: ONECUT2 (one cut homeobox 2 [Source:HGNC Symbol;Acc:HGNC:8139])

HSP 1 Score: 259.225 bits (661), Expect = 3.142e-76
Identity = 126/171 (73.68%), Postives = 147/171 (85.96%), Query Frame = 1

Query:  979 SQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            SQ +   Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE E +K +     KK RLVFT++QRRTL AIF+E KRPSK MQ TI+QQLGL ++TV+NFFMNARRRS++KWQD+
Sbjct:  322 SQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEPNKDRN-NSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDD 488

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BLAST of One cut domain family member vs. Ensembl Human
Match: ONECUT1 (one cut homeobox 1 [Source:HGNC Symbol;Acc:HGNC:8138])

HSP 1 Score: 122.865 bits (307), Expect = 2.327e-31
Identity = 56/64 (87.50%), Postives = 58/64 (90.62%), Query Frame = 1

Query: 1072 QAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKR 1263
            QAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA  +   R
Sbjct:  117 QAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAGTAREAR 180

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BLAST of One cut domain family member vs. Ensembl Human
Match: CUX1 (cut like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2557])

HSP 1 Score: 78.9518 bits (193), Expect = 3.810e-14
Identity = 56/174 (32.18%), Postives = 84/174 (48.28%), Query Frame = 1

Query: 1009 EINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEPE--FQRMSALRLAEISVNKRKEDEQSKPQEIKP------------------VKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRR 1467
            E++T  +++R+   L   ++ Q +F + IL  +QG++SDLL  PKPW KL   GRE F RM  WL +P    + M   R+ + +  KR+    S  Q  +P                  +KK R+V    ++  L   +Q+   PS      +A QL L  STV N+F N R R
Sbjct: 1069 ELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPPSVGTEYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSR 1242

HSP 2 Score: 67.0106 bits (162), Expect = 1.755e-10
Identity = 31/65 (47.69%), Postives = 46/65 (70.77%), Query Frame = 1

Query: 1009 EINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKL-KSGRETFRRMWKWL 1200
            E++T EL++++  +L +  I Q IF +++L  SQG++SD+L  PKPWSKL + GRE F RM  WL
Sbjct:  886 EVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWL 950

HSP 3 Score: 58.5362 bits (140), Expect = 6.228e-8
Identity = 38/113 (33.63%), Postives = 68/113 (60.18%), Query Frame = 1

Query:  961 GMQYNPSQQSLDMQI---DEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKP 1287
            GM  +PSQ      +   +E++T E+++++  +L +++I Q IF   +L  SQG++S++L  PKPW+KL   G+E F +M ++L   + Q + ALR    S+  R+  E ++P
Sbjct:  531 GMAPSPSQSESAGSVSEGEEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLS--DEQNILALR----SIQGRQRAEPAQP 637

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BLAST of One cut domain family member vs. Ensembl Celegans
Match: ceh-48 (One cut domain family member [Source:UniProtKB/TrEMBL;Acc:O45080])

HSP 1 Score: 228.794 bits (582), Expect = 3.977e-66
Identity = 116/162 (71.60%), Postives = 135/162 (83.33%), Query Frame = 1

Query: 1006 DEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQS--KPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQ 1485
            +E+NT+EL+ +I++ELKRYSIPQAIFA+R+L RSQGTLSDLLRNPKPWSKLKSGRETFRRM KWL+EPEFQRMSALRLA     KRKE+  +   PQ + P KK RLVF++IQRRTL AIF+ETKRPS+ MQ TI+QQL L  +TVANFFMNARRR  D  Q
Sbjct:  224 EELNTKELALQIAAELKRYSIPQAIFAERVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMAKWLEEPEFQRMSALRLAAC---KRKEEHTTPNSPQMVVP-KKTRLVFSDIQRRTLQAIFRETKRPSREMQITISQQLNLDPTTVANFFMNARRRGHDLKQ 381

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BLAST of One cut domain family member vs. Ensembl Celegans
Match: ceh-38 (Homeobox protein ceh-38 [Source:UniProtKB/Swiss-Prot;Acc:Q19720])

HSP 1 Score: 188.734 bits (478), Expect = 2.529e-50
Identity = 96/166 (57.83%), Postives = 121/166 (72.89%), Query Frame = 1

Query: 1012 INTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKR------------KEDEQSKPQEIKPVKKQ-RLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRS 1470
            I+T++L +RI+ ELK +SIPQAIFA+RIL RSQGTLSDLLRNPKPW+KLKSGRETFRRM+ W+ +P   R++ L +    VN+             +   +S      PV K+ RLVFT+IQ+RTL AIF+ET+RPS+ MQ TIA+ L L +STVANFFMNARRRS
Sbjct:  308 IDTKDLCKRIAFELKNHSIPQAIFAERILCRSQGTLSDLLRNPKPWNKLKSGRETFRRMYNWVAQPLATRLAILDMKTEDVNRASGMSPPTPAQNVRTHRRSTSDHDGPVSKRPRLVFTDIQKRTLQAIFKETQRPSREMQQTIAEHLRLDLSTVANFFMNARRRS 473

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BLAST of One cut domain family member vs. Ensembl Celegans
Match: ceh-38 (Homeobox protein ceh-38 [Source:UniProtKB/Swiss-Prot;Acc:Q19720])

HSP 1 Score: 188.348 bits (477), Expect = 2.932e-50
Identity = 96/166 (57.83%), Postives = 121/166 (72.89%), Query Frame = 1

Query: 1012 INTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKR------------KEDEQSKPQEIKPVKKQ-RLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRS 1470
            I+T++L +RI+ ELK +SIPQAIFA+RIL RSQGTLSDLLRNPKPW+KLKSGRETFRRM+ W+ +P   R++ L +    VN+             +   +S      PV K+ RLVFT+IQ+RTL AIF+ET+RPS+ MQ TIA+ L L +STVANFFMNARRRS
Sbjct:  311 IDTKDLCKRIAFELKNHSIPQAIFAERILCRSQGTLSDLLRNPKPWNKLKSGRETFRRMYNWVAQPLATRLAILDMKTEDVNRASGMSPPTPAQNVRTHRRSTSDHDGPVSKRPRLVFTDIQKRTLQAIFKETQRPSREMQQTIAEHLRLDLSTVANFFMNARRRS 476

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BLAST of One cut domain family member vs. Ensembl Celegans
Match: ceh-38 (Homeobox protein ceh-38 [Source:UniProtKB/Swiss-Prot;Acc:Q19720])

HSP 1 Score: 187.963 bits (476), Expect = 2.933e-50
Identity = 96/166 (57.83%), Postives = 121/166 (72.89%), Query Frame = 1

Query: 1012 INTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKR------------KEDEQSKPQEIKPVKKQ-RLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRS 1470
            I+T++L +RI+ ELK +SIPQAIFA+RIL RSQGTLSDLLRNPKPW+KLKSGRETFRRM+ W+ +P   R++ L +    VN+             +   +S      PV K+ RLVFT+IQ+RTL AIF+ET+RPS+ MQ TIA+ L L +STVANFFMNARRRS
Sbjct:  308 IDTKDLCKRIAFELKNHSIPQAIFAERILCRSQGTLSDLLRNPKPWNKLKSGRETFRRMYNWVAQPLATRLAILDMKTEDVNRASGMSPPTPAQNVRTHRRSTSDHDGPVSKRPRLVFTDIQKRTLQAIFKETQRPSREMQQTIAEHLRLDLSTVANFFMNARRRS 473

[Close]

BLAST of One cut domain family member vs. Ensembl Celegans
Match: ceh-38 (Homeobox protein ceh-38 [Source:UniProtKB/Swiss-Prot;Acc:Q19720])

HSP 1 Score: 187.578 bits (475), Expect = 3.224e-50
Identity = 96/166 (57.83%), Postives = 121/166 (72.89%), Query Frame = 1

Query: 1012 INTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKR------------KEDEQSKPQEIKPVKKQ-RLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRS 1470
            I+T++L +RI+ ELK +SIPQAIFA+RIL RSQGTLSDLLRNPKPW+KLKSGRETFRRM+ W+ +P   R++ L +    VN+             +   +S      PV K+ RLVFT+IQ+RTL AIF+ET+RPS+ MQ TIA+ L L +STVANFFMNARRRS
Sbjct:  311 IDTKDLCKRIAFELKNHSIPQAIFAERILCRSQGTLSDLLRNPKPWNKLKSGRETFRRMYNWVAQPLATRLAILDMKTEDVNRASGMSPPTPAQNVRTHRRSTSDHDGPVSKRPRLVFTDIQKRTLQAIFKETQRPSREMQQTIAEHLRLDLSTVANFFMNARRRS 476

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BLAST of One cut domain family member vs. Ensembl Fly
Match: onecut (gene:FBgn0028996 transcript:FBtr0089104)

HSP 1 Score: 160.229 bits (404), Expect = 8.013e-40
Identity = 77/107 (71.96%), Postives = 88/107 (82.24%), Query Frame = 1

Query:  943 GMMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKR 1263
            G +   G   N    S DM+  EINT++L+QRIS+ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRM+KWLQEPEFQRMSALR+A   + +R
Sbjct:  739 GTVSSGGAVSNRIANSSDME--EINTKDLAQRISAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMYKWLQEPEFQRMSALRMAAAQIPQR 843

HSP 2 Score: 108.612 bits (270), Expect = 1.014e-23
Identity = 54/96 (56.25%), Postives = 72/96 (75.00%), Query Frame = 1

Query: 1222 MSALRLAEISVNKRKEDEQSK--PQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHS 1503
            ++++ +  +   +RKE+ Q +  PQ  KP    RLVFT++QRRTL AIF+ETKRPSK MQ TIA+QLGL  +TV NFFMNARRRS+DKW+D++  S
Sbjct:  895 VTSVLVGSVVSCRRKEEPQIEQMPQPKKP----RLVFTDLQRRTLQAIFKETKRPSKEMQVTIARQLGLEPTTVGNFFMNARRRSMDKWRDDDSKS 986

[Close]

BLAST of One cut domain family member vs. Ensembl Fly
Match: onecut (gene:FBgn0028996 transcript:FBtr0310610)

HSP 1 Score: 160.229 bits (404), Expect = 8.013e-40
Identity = 77/107 (71.96%), Postives = 88/107 (82.24%), Query Frame = 1

Query:  943 GMMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKR 1263
            G +   G   N    S DM+  EINT++L+QRIS+ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRM+KWLQEPEFQRMSALR+A   + +R
Sbjct:  739 GTVSSGGAVSNRIANSSDME--EINTKDLAQRISAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMYKWLQEPEFQRMSALRMAAAQIPQR 843

HSP 2 Score: 108.612 bits (270), Expect = 1.014e-23
Identity = 54/96 (56.25%), Postives = 72/96 (75.00%), Query Frame = 1

Query: 1222 MSALRLAEISVNKRKEDEQSK--PQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHS 1503
            ++++ +  +   +RKE+ Q +  PQ  KP    RLVFT++QRRTL AIF+ETKRPSK MQ TIA+QLGL  +TV NFFMNARRRS+DKW+D++  S
Sbjct:  895 VTSVLVGSVVSCRRKEEPQIEQMPQPKKP----RLVFTDLQRRTLQAIFKETKRPSKEMQVTIARQLGLEPTTVGNFFMNARRRSMDKWRDDDSKS 986

[Close]

BLAST of One cut domain family member vs. Ensembl Fly
Match: ct (gene:FBgn0004198 transcript:FBtr0071068)

HSP 1 Score: 80.4925 bits (197), Expect = 6.106e-15
Identity = 59/210 (28.10%), Postives = 91/210 (43.33%), Query Frame = 1

Query:  937 VHGM--MHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEP-EFQRMSALRLAEISVNKRKEDEQSKPQE-----------------------------IKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRR 1467
            VHG   M       +P+   +     +++T +++ +I   L   +I Q IF + +L  SQG++S+LL  PKPW  L   GRE F RM  WL +    +R+  L+      +KR+       Q+                               P KKQR++F+E Q+  L   F     P+      +A +LGLA  T+ N+F N R R
Sbjct: 1590 VHGTNAMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKPWHMLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMR 1799

HSP 2 Score: 67.0106 bits (162), Expect = 8.247e-11
Identity = 33/77 (42.86%), Postives = 50/77 (64.94%), Query Frame = 1

Query:  979 SQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKL-KSGRETFRRMWKWLQE 1206
            +QQ  DM  + +NT ++ +R+   L +YSI Q +F + +L  SQG++SDLL  PKPW  L + GRE F RM  +L++
Sbjct: 1329 TQQQFDM-FNNLNTEDIVRRVKEALSQYSISQRLFGESVLGLSQGSVSDLLARPKPWHMLTQKGREPFIRMKMFLED 1404

HSP 3 Score: 62.7734 bits (151), Expect = 1.420e-9
Identity = 28/63 (44.44%), Postives = 44/63 (69.84%), Query Frame = 1

Query: 1012 INTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKL-KSGRETFRRMWKW 1197
            ++T  +S+R+   L  ++I Q +FA+ IL  SQGT+S+LL  PKPW KL + GR+++R+M  W
Sbjct:  886 LDTLHISRRVRELLSVHNIGQRLFAKYILGLSQGTVSELLSKPKPWDKLTEKGRDSYRKMHAW 948

[Close]

BLAST of One cut domain family member vs. Ensembl Fly
Match: ct (gene:FBgn0004198 transcript:FBtr0331733)

HSP 1 Score: 80.4925 bits (197), Expect = 6.316e-15
Identity = 59/210 (28.10%), Postives = 91/210 (43.33%), Query Frame = 1

Query:  937 VHGM--MHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEP-EFQRMSALRLAEISVNKRKEDEQSKPQE-----------------------------IKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRR 1467
            VHG   M       +P+   +     +++T +++ +I   L   +I Q IF + +L  SQG++S+LL  PKPW  L   GRE F RM  WL +    +R+  L+      +KR+       Q+                               P KKQR++F+E Q+  L   F     P+      +A +LGLA  T+ N+F N R R
Sbjct: 1589 VHGTNAMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKPWHMLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMR 1798

HSP 2 Score: 67.0106 bits (162), Expect = 8.177e-11
Identity = 33/77 (42.86%), Postives = 50/77 (64.94%), Query Frame = 1

Query:  979 SQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKL-KSGRETFRRMWKWLQE 1206
            +QQ  DM  + +NT ++ +R+   L +YSI Q +F + +L  SQG++SDLL  PKPW  L + GRE F RM  +L++
Sbjct: 1328 TQQQFDM-FNNLNTEDIVRRVKEALSQYSISQRLFGESVLGLSQGSVSDLLARPKPWHMLTQKGREPFIRMKMFLED 1403

HSP 3 Score: 62.7734 bits (151), Expect = 1.432e-9
Identity = 28/63 (44.44%), Postives = 44/63 (69.84%), Query Frame = 1

Query: 1012 INTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKL-KSGRETFRRMWKW 1197
            ++T  +S+R+   L  ++I Q +FA+ IL  SQGT+S+LL  PKPW KL + GR+++R+M  W
Sbjct:  885 LDTLHISRRVRELLSVHNIGQRLFAKYILGLSQGTVSELLSKPKPWDKLTEKGRDSYRKMHAW 947

[Close]

BLAST of One cut domain family member vs. Ensembl Fly
Match: ct (gene:FBgn0004198 transcript:FBtr0305134)

HSP 1 Score: 80.1073 bits (196), Expect = 8.494e-15
Identity = 59/210 (28.10%), Postives = 91/210 (43.33%), Query Frame = 1

Query:  937 VHGM--MHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEP-EFQRMSALRLAEISVNKRKEDEQSKPQE-----------------------------IKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRR 1467
            VHG   M       +P+   +     +++T +++ +I   L   +I Q IF + +L  SQG++S+LL  PKPW  L   GRE F RM  WL +    +R+  L+      +KR+       Q+                               P KKQR++F+E Q+  L   F     P+      +A +LGLA  T+ N+F N R R
Sbjct: 1580 VHGTNAMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKPWHMLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMR 1789

HSP 2 Score: 67.0106 bits (162), Expect = 8.820e-11
Identity = 33/77 (42.86%), Postives = 50/77 (64.94%), Query Frame = 1

Query:  979 SQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKL-KSGRETFRRMWKWLQE 1206
            +QQ  DM  + +NT ++ +R+   L +YSI Q +F + +L  SQG++SDLL  PKPW  L + GRE F RM  +L++
Sbjct: 1319 TQQQFDM-FNNLNTEDIVRRVKEALSQYSISQRLFGESVLGLSQGSVSDLLARPKPWHMLTQKGREPFIRMKMFLED 1394

HSP 3 Score: 62.7734 bits (151), Expect = 1.493e-9
Identity = 28/63 (44.44%), Postives = 44/63 (69.84%), Query Frame = 1

Query: 1012 INTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKL-KSGRETFRRMWKW 1197
            ++T  +S+R+   L  ++I Q +FA+ IL  SQGT+S+LL  PKPW KL + GR+++R+M  W
Sbjct:  876 LDTLHISRRVRELLSVHNIGQRLFAKYILGLSQGTVSELLSKPKPWDKLTEKGRDSYRKMHAW 938

[Close]

BLAST of One cut domain family member vs. Ensembl Zebrafish
Match: onecut3b (one cut homeobox 3b [Source:ZFIN;Acc:ZDB-GENE-130805-1])

HSP 1 Score: 271.166 bits (692), Expect = 1.269e-81
Identity = 129/167 (77.25%), Postives = 148/167 (88.62%), Query Frame = 1

Query: 1003 IDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHS 1503
            ++EINT+E++QRI++ELKRYSIPQAIFAQRIL RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE EQ K + + P KKQRLVFT++QRRTL+AIF+E KRPSK MQ TI+QQLGL +STV+NFFMNARRR +D+WQDE+  S
Sbjct:  265 VEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEQHKDRNMVP-KKQRLVFTDLQRRTLIAIFKENKRPSKEMQITISQQLGLELSTVSNFFMNARRRCVDRWQDEHASS 427

[Close]

BLAST of One cut domain family member vs. Ensembl Zebrafish
Match: onecut3a (one cut homeobox 3a [Source:ZFIN;Acc:ZDB-GENE-050208-744])

HSP 1 Score: 270.396 bits (690), Expect = 2.890e-81
Identity = 127/166 (76.51%), Postives = 147/166 (88.55%), Query Frame = 1

Query: 1003 IDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPH 1500
            ++EINT+E++QRI++ELKRYSIPQAIFAQRIL RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE EQ K + + P KKQRLVFT++QRRTL+AIF+E KRPSK MQ TI+QQLGL +STV+NFFMNARRR +D+W +E+ H
Sbjct:  274 VEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEQHKERNMAP-KKQRLVFTDLQRRTLIAIFKENKRPSKEMQLTISQQLGLELSTVSNFFMNARRRCVDRWHEEHHH 435

[Close]

BLAST of One cut domain family member vs. Ensembl Zebrafish
Match: onecut2 (one cut homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-120215-73])

HSP 1 Score: 265.774 bits (678), Expect = 2.333e-79
Identity = 133/182 (73.08%), Postives = 151/182 (82.97%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHSITMESMSPTNSPSS 1545
            Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE + SK +   P KK RLVFT++QRRTL+AIF+E KRPSK MQ TI+QQLGL +STV+NFFMNARRRS+DKW DE          SP NS SS
Sbjct:  286 QLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQDPSKDRSNTP-KKSRLVFTDLQRRTLLAIFKENKRPSKEMQMTISQQLGLELSTVSNFFMNARRRSLDKWLDEG---------SPNNSSSS 454

[Close]

BLAST of One cut domain family member vs. Ensembl Zebrafish
Match: onecut1 (one cut homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1469])

HSP 1 Score: 261.151 bits (666), Expect = 9.408e-78
Identity = 122/164 (74.39%), Postives = 142/164 (86.59%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            Q++E+NT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE E  K +     KK RLVFT++QRRTL AIF+E KRPSK +Q TI+QQLGL ++TV+NFFMNARRRS+DKW D+
Sbjct:  279 QMEEVNTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEHGKGERGNISKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELATVSNFFMNARRRSLDKWLDD 439

[Close]

BLAST of One cut domain family member vs. Ensembl Zebrafish
Match: onecut1 (one cut homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1469])

HSP 1 Score: 259.996 bits (663), Expect = 2.744e-77
Identity = 122/166 (73.49%), Postives = 142/166 (85.54%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA--EISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            Q++E+NT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA       KRKE E  K +     KK RLVFT++QRRTL AIF+E KRPSK +Q TI+QQLGL ++TV+NFFMNARRRS+DKW D+
Sbjct:  279 QMEEVNTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAGERTIACKRKEQEHGKGERGNISKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELATVSNFFMNARRRSLDKWLDD 444

[Close]

BLAST of One cut domain family member vs. Ensembl Xenopus
Match: ENSXETT00000038157.1 (one cut homeobox 3 [Source:NCBI gene;Acc:100491290])

HSP 1 Score: 265.774 bits (678), Expect = 1.452e-79
Identity = 127/171 (74.27%), Postives = 151/171 (88.30%), Query Frame = 1

Query:  979 SQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            SQ   + Q++EINT+E++QRI++ELKRYSIPQAIFAQRIL RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE EQ K + ++P KKQRLVFT++QRRTL+AIF+E KRPSK MQ TI+QQLGL ++TV+NFFMNARRR +++WQ++
Sbjct:  255 SQAGGNGQVEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEQQKDRNLQP-KKQRLVFTDLQRRTLIAIFKENKRPSKEMQITISQQLGLELNTVSNFFMNARRRCMNRWQED 421

[Close]

BLAST of One cut domain family member vs. Ensembl Xenopus
Match: onecut1 (one cut homeobox 1 [Source:NCBI gene;Acc:100101763])

HSP 1 Score: 264.233 bits (674), Expect = 1.044e-78
Identity = 127/164 (77.44%), Postives = 144/164 (87.80%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE E  K +   P KK RLVFT++QRRTL AIF+E KRPSK +Q TI+QQLGL +STV+NFFMNARRRS+DKWQDE
Sbjct:  281 QMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEHGKDRGNTP-KKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDE 440

[Close]

BLAST of One cut domain family member vs. Ensembl Xenopus
Match: mgll (monoglyceride lipase [Source:Xenbase;Acc:XB-GENE-942085])

HSP 1 Score: 256.914 bits (655), Expect = 1.488e-76
Identity = 127/191 (66.49%), Postives = 151/191 (79.06%), Query Frame = 1

Query:  940 HGMMHHS---GMQYNPSQQS----LDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            H  +HH      + NP  Q+    +  Q++EINT++++QRI +ELKRYSIPQAIFA+R+L RSQGTLSDLLRNPKPWSKLKSGRETF+RMW+WLQEPEFQRM+ALRL      KRKE EQSK +     K+ RLVFT+IQRRTL AIF E +RPSK +Q TIAQQLGL +STV+NFFMNARRRS+DKW DE
Sbjct:  206 HHYVHHRPEINCRQNPPMQTQNTAISNQLEEINTKDVAQRIIAELKRYSIPQAIFAERVLCRSQGTLSDLLRNPKPWSKLKSGRETFKRMWRWLQEPEFQRMAALRLEAC---KRKEQEQSKAERNHVPKRHRLVFTDIQRRTLHAIFHENQRPSKELQITIAQQLGLELSTVSNFFMNARRRSLDKWMDE 393

[Close]

BLAST of One cut domain family member vs. Ensembl Xenopus
Match: ONECUT2 (one cut homeobox 2 [Source:NCBI gene;Acc:100485320])

HSP 1 Score: 257.299 bits (656), Expect = 5.292e-76
Identity = 124/164 (75.61%), Postives = 144/164 (87.80%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE E +K +     KK RLVFT++QRRTL AIF+E KRPSK MQ TI+QQLGL ++TV+NFFMNARRRS++KWQD+
Sbjct:  288 QLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEPNKDRN-NTQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELNTVSNFFMNARRRSLEKWQDD 447

[Close]

BLAST of One cut domain family member vs. Ensembl Xenopus
Match: ONECUT2 (one cut homeobox 2 [Source:NCBI gene;Acc:100485320])

HSP 1 Score: 254.988 bits (650), Expect = 4.637e-75
Identity = 126/171 (73.68%), Postives = 146/171 (85.38%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA--EISV-----NKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA  E S       KRKE E +K +     KK RLVFT++QRRTL AIF+E KRPSK MQ TI+QQLGL ++TV+NFFMNARRRS++KWQD+
Sbjct:  288 QLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAPEFSAILQSSCKRKEQEPNKDRN-NTQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELNTVSNFFMNARRRSLEKWQDD 457

[Close]

BLAST of One cut domain family member vs. Ensembl Mouse
Match: Onecut1 (one cut domain, family member 1 [Source:MGI Symbol;Acc:MGI:1196423])

HSP 1 Score: 265.003 bits (676), Expect = 5.338e-79
Identity = 127/164 (77.44%), Postives = 144/164 (87.80%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE E  K +   P KK RLVFT++QRRTL AIF+E KRPSK +Q TI+QQLGL +STV+NFFMNARRRS+DKWQDE
Sbjct:  288 QMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEHGKDRGNTP-KKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDE 447

[Close]

BLAST of One cut domain family member vs. Ensembl Mouse
Match: Onecut3 (one cut domain, family member 3 [Source:MGI Symbol;Acc:MGI:1891409])

HSP 1 Score: 259.225 bits (661), Expect = 1.378e-76
Identity = 124/162 (76.54%), Postives = 146/162 (90.12%), Query Frame = 1

Query: 1006 DEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            +EINT+E++QRI++ELKRYSIPQAIFAQRIL RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE +Q K + ++P KKQRLVFT++QRRTL+AIF+E KRPSK MQATI+QQLGL ++TV+NFFMNARRR +++W +E
Sbjct:  316 EEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQDQQKERALQP-KKQRLVFTDLQRRTLIAIFKENKRPSKEMQATISQQLGLELNTVSNFFMNARRRCMNRWAEE 473

[Close]

BLAST of One cut domain family member vs. Ensembl Mouse
Match: Onecut2 (one cut domain, family member 2 [Source:MGI Symbol;Acc:MGI:1891408])

HSP 1 Score: 259.225 bits (661), Expect = 2.019e-76
Identity = 126/171 (73.68%), Postives = 147/171 (85.96%), Query Frame = 1

Query:  979 SQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            SQ +   Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE E +K +     KK RLVFT++QRRTL AIF+E KRPSK MQ TI+QQLGL ++TV+NFFMNARRRS++KWQD+
Sbjct:  323 SQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEPNKDRN-NSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDD 489

[Close]

BLAST of One cut domain family member vs. Ensembl Mouse
Match: Cux1 (cut-like homeobox 1 [Source:MGI Symbol;Acc:MGI:88568])

HSP 1 Score: 78.5666 bits (192), Expect = 2.742e-14
Identity = 61/192 (31.77%), Postives = 90/192 (46.88%), Query Frame = 1

Query:  955 HSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEPE--FQRMSALRLAEISVNKRKEDEQSKPQEIKP------------------VKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRR 1467
            HS +    S Q L     E++T  +++R+   L   ++ Q +F + IL  +QG++SDLL  PKPW KL   GRE F RM  WL +P    + M   R+ + +  KR+    S  Q  +P                  +KK R+V    ++  L   +Q+   PS      +A QL L  STV N+F N R R
Sbjct:  980 HSAL----SIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPPSVGIDYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEELATQLNLKTSTVINWFHNYRSR 1167

HSP 2 Score: 66.6254 bits (161), Expect = 1.332e-10
Identity = 31/65 (47.69%), Postives = 46/65 (70.77%), Query Frame = 1

Query: 1009 EINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKL-KSGRETFRRMWKWL 1200
            E++T EL++++  +L +  I Q IF +++L  SQG++SD+L  PKPWSKL + GRE F RM  WL
Sbjct:  811 EVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWL 875

HSP 3 Score: 59.3066 bits (142), Expect = 2.549e-8
Identity = 36/96 (37.50%), Postives = 60/96 (62.50%), Query Frame = 1

Query:  961 GMQYNPSQQSLDMQI---DEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEPEFQRMSALR 1236
            GM  +PSQ      I   +EI+T E+++++  +L +++I Q IF   +L  SQG++S++L  PKPW+KL   G+E F +M ++L   + Q + ALR
Sbjct:  403 GMAPSPSQSESAGSISEGEEIDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLS--DEQNILALR 496

[Close]

BLAST of One cut domain family member vs. Ensembl Mouse
Match: Cux1 (cut-like homeobox 1 [Source:MGI Symbol;Acc:MGI:88568])

HSP 1 Score: 78.5666 bits (192), Expect = 3.533e-14
Identity = 61/192 (31.77%), Postives = 90/192 (46.88%), Query Frame = 1

Query:  955 HSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEPE--FQRMSALRLAEISVNKRKEDEQSKPQEIKP------------------VKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRR 1467
            HS +    S Q L     E++T  +++R+   L   ++ Q +F + IL  +QG++SDLL  PKPW KL   GRE F RM  WL +P    + M   R+ + +  KR+    S  Q  +P                  +KK R+V    ++  L   +Q+   PS      +A QL L  STV N+F N R R
Sbjct: 1100 HSAL----SIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPPSVGIDYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEELATQLNLKTSTVINWFHNYRSR 1287

HSP 2 Score: 66.6254 bits (161), Expect = 1.313e-10
Identity = 31/65 (47.69%), Postives = 46/65 (70.77%), Query Frame = 1

Query: 1009 EINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKL-KSGRETFRRMWKWL 1200
            E++T EL++++  +L +  I Q IF +++L  SQG++SD+L  PKPWSKL + GRE F RM  WL
Sbjct:  931 EVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWL 995

HSP 3 Score: 59.3066 bits (142), Expect = 2.657e-8
Identity = 36/96 (37.50%), Postives = 60/96 (62.50%), Query Frame = 1

Query:  961 GMQYNPSQQSLDMQI---DEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEPEFQRMSALR 1236
            GM  +PSQ      I   +EI+T E+++++  +L +++I Q IF   +L  SQG++S++L  PKPW+KL   G+E F +M ++L   + Q + ALR
Sbjct:  523 GMAPSPSQSESAGSISEGEEIDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLS--DEQNILALR 616

[Close]

BLAST of One cut domain family member vs. UniProt/SwissProt
Match: sp|O08755|HNF6_MOUSE (Hepatocyte nuclear factor 6 OS=Mus musculus OX=10090 GN=Onecut1 PE=1 SV=1)

HSP 1 Score: 265.003 bits (676), Expect = 3.734e-78
Identity = 127/164 (77.44%), Postives = 144/164 (87.80%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE E  K +   P KK RLVFT++QRRTL AIF+E KRPSK +Q TI+QQLGL +STV+NFFMNARRRS+DKWQDE
Sbjct:  288 QMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEHGKDRGNTP-KKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDE 447

[Close]

BLAST of One cut domain family member vs. UniProt/SwissProt
Match: sp|P70512|HNF6_RAT (Hepatocyte nuclear factor 6 OS=Rattus norvegicus OX=10116 GN=Onecut1 PE=1 SV=1)

HSP 1 Score: 265.003 bits (676), Expect = 4.180e-78
Identity = 127/164 (77.44%), Postives = 144/164 (87.80%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE E  K +   P KK RLVFT++QRRTL AIF+E KRPSK +Q TI+QQLGL +STV+NFFMNARRRS+DKWQDE
Sbjct:  288 QMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEHGKDRGNTP-KKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDE 447

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BLAST of One cut domain family member vs. UniProt/SwissProt
Match: sp|Q9UBC0|HNF6_HUMAN (Hepatocyte nuclear factor 6 OS=Homo sapiens OX=9606 GN=ONECUT1 PE=2 SV=1)

HSP 1 Score: 263.848 bits (673), Expect = 8.406e-78
Identity = 127/164 (77.44%), Postives = 144/164 (87.80%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE E  K +   P KK RLVFT++QRRTL AIF+E KRPSK +Q TI+QQLGL +STV+NFFMNARRRS+DKWQDE
Sbjct:  288 QMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEHGKDRGNTP-KKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDE 447

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BLAST of One cut domain family member vs. UniProt/SwissProt
Match: sp|Q8K557|ONEC3_MOUSE (One cut domain family member 3 OS=Mus musculus OX=10090 GN=Onecut3 PE=1 SV=2)

HSP 1 Score: 259.225 bits (661), Expect = 9.636e-76
Identity = 124/162 (76.54%), Postives = 146/162 (90.12%), Query Frame = 1

Query: 1006 DEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            +EINT+E++QRI++ELKRYSIPQAIFAQRIL RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE +Q K + ++P KKQRLVFT++QRRTL+AIF+E KRPSK MQATI+QQLGL ++TV+NFFMNARRR +++W +E
Sbjct:  316 EEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQDQQKERALQP-KKQRLVFTDLQRRTLIAIFKENKRPSKEMQATISQQLGLELNTVSNFFMNARRRCMNRWAEE 473

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BLAST of One cut domain family member vs. UniProt/SwissProt
Match: sp|O60422|ONEC3_HUMAN (One cut domain family member 3 OS=Homo sapiens OX=9606 GN=ONECUT3 PE=1 SV=2)

HSP 1 Score: 259.225 bits (661), Expect = 1.060e-75
Identity = 124/162 (76.54%), Postives = 145/162 (89.51%), Query Frame = 1

Query: 1006 DEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            +EINT+E++QRI++ELKRYSIPQAIFAQRIL RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE EQ K + ++P KKQRLVFT++QRRTL+AIF+E KRPSK MQ TI+QQLGL ++TV+NFFMNARRR +++W +E
Sbjct:  319 EEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEQQKERALQP-KKQRLVFTDLQRRTLIAIFKENKRPSKEMQVTISQQLGLELNTVSNFFMNARRRCMNRWAEE 476

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BLAST of One cut domain family member vs. TrEMBL
Match: A0A1S3J3A5 (One cut domain family member OS=Lingula unguis OX=7574 GN=LOC106169803 PE=3 SV=1)

HSP 1 Score: 278.485 bits (711), Expect = 3.383e-81
Identity = 141/188 (75.00%), Postives = 158/188 (84.04%), Query Frame = 1

Query:  940 HG---MMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQ-SKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            HG   M   SG+    S+ S   +++EINT+EL+QRISSELKRYSIPQA+FAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE EQ S P++ +  KK RLVFT+IQRRTL AIF+ETKRPSK MQATIAQQLGL V+TVANFFMNARRRS+DKW+DE
Sbjct:  227 HGLSVMKERSGLD---SKSSNSQELEEINTKELAQRISSELKRYSIPQAVFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAGGLSCKRKEAEQVSPPEDSRAPKKPRLVFTDIQRRTLHAIFKETKRPSKEMQATIAQQLGLEVTTVANFFMNARRRSLDKWKDE 411

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BLAST of One cut domain family member vs. TrEMBL
Match: A0A4W4FMU2 (One cut domain family member OS=Electrophorus electricus OX=8005 GN=LOC113582383 PE=3 SV=1)

HSP 1 Score: 278.87 bits (712), Expect = 4.135e-81
Identity = 131/168 (77.98%), Postives = 150/168 (89.29%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHS 1503
            Q++EINT+E++QRI++ELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE EQ K + + P KKQRLVFT++QRRTL+AIF+E +RPSK MQ TIAQQLGL +STV+NFFMNARRR +D+W DE+ HS
Sbjct:  264 QVEEINTKEVAQRITAELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEQLKERSVAP-KKQRLVFTDLQRRTLVAIFKENRRPSKEMQVTIAQQLGLELSTVSNFFMNARRRCVDRWHDEHQHS 427

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BLAST of One cut domain family member vs. TrEMBL
Match: A0A1S3J4Y3 (One cut domain family member OS=Lingula unguis OX=7574 GN=LOC106169803 PE=3 SV=1)

HSP 1 Score: 277.33 bits (708), Expect = 7.475e-81
Identity = 141/188 (75.00%), Postives = 158/188 (84.04%), Query Frame = 1

Query:  940 HG---MMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQ-SKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            HG   M   SG+    S+ S   +++EINT+EL+QRISSELKRYSIPQA+FAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE EQ S P++ +  KK RLVFT+IQRRTL AIF+ETKRPSK MQATIAQQLGL V+TVANFFMNARRRS+DKW+DE
Sbjct:  227 HGLSVMKERSGLD---SKSSNSQELEEINTKELAQRISSELKRYSIPQAVFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEAEQVSPPEDSRAPKKPRLVFTDIQRRTLHAIFKETKRPSKEMQATIAQQLGLEVTTVANFFMNARRRSLDKWKDE 408

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BLAST of One cut domain family member vs. TrEMBL
Match: A0A2C9K7Y3 (One cut domain family member OS=Biomphalaria glabrata OX=6526 GN=106074576 PE=3 SV=1)

HSP 1 Score: 276.559 bits (706), Expect = 4.739e-80
Identity = 140/192 (72.92%), Postives = 154/192 (80.21%), Query Frame = 1

Query:  988 SLDMQ------IDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA----------------EISVNKRKE-DEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDEN 1494
            SLD+Q      I+EINT+EL+QRISSELKRYSIPQA+FAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA                 I+  KRKE D    P+E +P KK RLVFT+IQRRTL AIF+ETKRPSK MQ TIAQQLGL V+TVANFFMNARRRS+DKWQD+N
Sbjct:  257 SLDLQKPQQQEIEEINTKELAQRISSELKRYSIPQAVFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAGAITGVTRANNVYTSSPIAACKRKELDVDKSPEENRPPKKPRLVFTDIQRRTLHAIFKETKRPSKEMQQTIAQQLGLEVTTVANFFMNARRRSLDKWQDDN 448

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BLAST of One cut domain family member vs. TrEMBL
Match: V4CJP9 (One cut domain family member OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_199735 PE=3 SV=1)

HSP 1 Score: 270.396 bits (690), Expect = 9.718e-79
Identity = 137/180 (76.11%), Postives = 154/180 (85.56%), Query Frame = 1

Query:  958 SGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKP-QEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDEN 1494
            SG++ +P +Q L+    EINT+EL+QRISSELKRYSIPQA+FAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE E  K  ++ +  KK RLVFT+IQRRTL AIF+ETKRPSK MQ TIAQQLGL V+TVANFFMNARRRS+DKWQD+N
Sbjct:  199 SGLE-SPDKQDLE----EINTKELAQRISSELKRYSIPQAVFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEPDKSIEDPRSPKKPRLVFTDIQRRTLHAIFKETKRPSKEMQTTIAQQLGLEVTTVANFFMNARRRSLDKWQDDN 370

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BLAST of One cut domain family member vs. Ensembl Cavefish
Match: onecut3b (one cut domain family member 3-like [Source:NCBI gene;Acc:103028184])

HSP 1 Score: 272.707 bits (696), Expect = 4.737e-82
Identity = 128/164 (78.05%), Postives = 146/164 (89.02%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            Q++EINT+E++QRI++ELKRYSIPQAIFAQRIL RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE EQ K + + P KKQRLVFT++QRRTL+AIF+E KRPSK MQ TI+QQLGL +STV+NFFMNARRR +D+W DE
Sbjct:  285 QVEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEQHKDRNLAP-KKQRLVFTDLQRRTLIAIFKENKRPSKEMQITISQQLGLELSTVSNFFMNARRRCVDRWHDE 444

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BLAST of One cut domain family member vs. Ensembl Cavefish
Match: ENSAMXT00000055666.1 (one cut domain family member 3-like [Source:NCBI gene;Acc:103046190])

HSP 1 Score: 268.855 bits (686), Expect = 1.106e-80
Identity = 129/167 (77.25%), Postives = 147/167 (88.02%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPH 1500
            Q +EINT+E++QRI++ELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE EQ K +   P KKQRLVFT++QRRTL+AIF+E KRPSK MQ TIAQQLGL ++TV+NFFMNARRR +D+W +E+ H
Sbjct:  270 QAEEINTKEVAQRITAELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEQMKERNSVP-KKQRLVFTDLQRRTLIAIFKENKRPSKEMQVTIAQQLGLELNTVSNFFMNARRRCVDRWHEEHQH 432

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BLAST of One cut domain family member vs. Ensembl Cavefish
Match: onecut2 (one cut homeobox 2 [Source:NCBI gene;Acc:103028667])

HSP 1 Score: 264.233 bits (674), Expect = 1.110e-78
Identity = 126/163 (77.30%), Postives = 144/163 (88.34%), Query Frame = 1

Query: 1003 IDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            ++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE + SK +   P KK RLVFT++QRRTL+AIF+E KRPSK MQ TI+QQLGL +STV+NFFMNARRRS+DKW DE
Sbjct:  306 LEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQDSSKERSNTP-KKSRLVFTDLQRRTLLAIFKENKRPSKEMQLTISQQLGLELSTVSNFFMNARRRSLDKWMDE 464

[Close]

BLAST of One cut domain family member vs. Ensembl Cavefish
Match: onecut1 (one cut homeobox 1 [Source:NCBI gene;Acc:103047808])

HSP 1 Score: 260.381 bits (664), Expect = 2.707e-77
Identity = 124/167 (74.25%), Postives = 146/167 (87.43%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA-EISVN-KRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDEN 1494
            Q++E+NT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA E ++  KRKE EQ K +     KK RLVFT++QRRTL AIF+E KRPSK +Q TI+QQLGL ++TV+NFFMNARRRS+DKW D+ 
Sbjct:  292 QVEEVNTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAGEPAIACKRKEQEQGKGERGSISKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELATVSNFFMNARRRSLDKWLDDG 458

[Close]

BLAST of One cut domain family member vs. Ensembl Cavefish
Match: onecutl (hepatocyte nuclear factor 6-like [Source:NCBI gene;Acc:103044517])

HSP 1 Score: 240.35 bits (612), Expect = 3.811e-70
Identity = 112/162 (69.14%), Postives = 140/162 (86.42%), Query Frame = 1

Query: 1006 DEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            +EINT++++QRI +ELKRYSIPQAIFA+R+L RSQGTLSDLLRNPKPW KLKSGRETF+RM +WLQEPEFQRM++LRL      KRKE EQSK +  +  K+ RLVFT++QRRTLMAIF+E +RP+K +Q TIAQQLGL +STV+NFFMNARRR++++W +E
Sbjct:  272 EEINTKDVAQRIITELKRYSIPQAIFAERVLCRSQGTLSDLLRNPKPWGKLKSGRETFKRMSRWLQEPEFQRMASLRLEAC---KRKEQEQSKQERNQGPKRTRLVFTDLQRRTLMAIFRENQRPAKDLQVTIAQQLGLELSTVSNFFMNARRRNLNRWSEE 430

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BLAST of One cut domain family member vs. Ensembl Sea Lamprey
Match: onecut3a (one cut homeobox 3a [Source:ZFIN;Acc:ZDB-GENE-050208-744])

HSP 1 Score: 162.54 bits (410), Expect = 2.246e-45
Identity = 73/81 (90.12%), Postives = 79/81 (97.53%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA 1242
            Q +EINTRE++QRIS+ELKRYSIPQA+FAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA
Sbjct:  168 QAEEINTREVAQRISTELKRYSIPQAVFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA 248

[Close]

BLAST of One cut domain family member vs. Ensembl Nematostella
Match: EDO45004 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU16])

HSP 1 Score: 164.466 bits (415), Expect = 1.055e-46
Identity = 82/155 (52.90%), Postives = 116/155 (74.84%), Query Frame = 1

Query: 1012 INTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSID 1476
            I+T+ ++ +++ EL+RY IPQA+FA+++L+RSQGTLSDLLR PKPW++++ G+  F+RM +WL+ PE +R+  LR+ E S  KR   E     E  P KK R  FTE Q+RTL AIF+ETK+P+K MQ  +A++LGL +++VANFFMNARRR  D
Sbjct:   25 IDTKAMALKLTEELRRYHIPQAVFAKKVLNRSQGTLSDLLRKPKPWNEMRLGKAIFKRMKEWLELPEVKRIPQLRM-EDSRAKRSNSESD--VEAAPSKKIRRQFTETQKRTLFAIFKETKKPTKDMQKAVAEELGLDLNSVANFFMNARRRHTD 176

[Close]

BLAST of One cut domain family member vs. Ensembl Nematostella
Match: EDO36708 (Onecut-like protein; Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHT3])

HSP 1 Score: 68.5514 bits (166), Expect = 9.031e-12
Identity = 46/159 (28.93%), Postives = 82/159 (51.57%), Query Frame = 1

Query:  994 DMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLR--NPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARR 1464
            DM ++  N +E+ +R+S  LKR  + Q  FA+ IL R Q TL+ LL     + W K  + R  + +M+ ++++ + Q  S LRLA      + E ++ K    + + + R  F+++Q   L  +F +T+ PS  +   +   L L ++    +F N RR
Sbjct:   44 DMIVNSTNPKEIVERVSLWLKRNRVSQIQFAKTILGRGQPTLNALLAQGQTEEWPKEGTKRRHYIKMYDFMEDEDLQ--STLRLA----GAKYEHQRVKVYSQEHIHRPRTRFSDLQLAALDMLFTKTQNPSVEVLEELCNTLHLELAQAQIWFQNKRR 196

[Close]

BLAST of One cut domain family member vs. Ensembl Medaka
Match: onecut3a (one cut domain family member 2 [Source:NCBI gene;Acc:101173926])

HSP 1 Score: 267.314 bits (682), Expect = 3.033e-80
Identity = 126/163 (77.30%), Postives = 144/163 (88.34%), Query Frame = 1

Query: 1006 DEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDEN 1494
            +EINT+E++QRI++ELKRYSIPQAIFAQRIL RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE EQ K +   P KKQRLVFT++QRRTL+AIF+E KRPSK MQ TI+QQLGL +STV+NFFMNARRR +D+W D++
Sbjct:  268 EEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQEQHKDRNTAP-KKQRLVFTDLQRRTLIAIFKENKRPSKEMQITISQQLGLELSTVSNFFMNARRRCVDRWHDDH 426

[Close]

BLAST of One cut domain family member vs. Ensembl Medaka
Match: onecut2 (one cut homeobox 2 [Source:NCBI gene;Acc:101162148])

HSP 1 Score: 264.233 bits (674), Expect = 1.090e-78
Identity = 124/165 (75.15%), Postives = 145/165 (87.88%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDEN 1494
            Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE + +K +   P KK RLVFT++QRRTL+AIF+E KRPSK MQ TI+QQLGL ++TV+NFFMNARRRS+DKW D+ 
Sbjct:  307 QLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQDTAKDRSNTP-KKSRLVFTDLQRRTLLAIFKENKRPSKEMQLTISQQLGLELTTVSNFFMNARRRSLDKWTDDG 467

[Close]

BLAST of One cut domain family member vs. Ensembl Medaka
Match: onecut2 (one cut homeobox 2 [Source:NCBI gene;Acc:101162148])

HSP 1 Score: 265.003 bits (676), Expect = 1.288e-78
Identity = 124/165 (75.15%), Postives = 145/165 (87.88%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDEN 1494
            Q++EINT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE + +K +   P KK RLVFT++QRRTL+AIF+E KRPSK MQ TI+QQLGL ++TV+NFFMNARRRS+DKW D+ 
Sbjct:  331 QLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEQDTAKDRSNTP-KKSRLVFTDLQRRTLLAIFKENKRPSKEMQLTISQQLGLELTTVSNFFMNARRRSLDKWTDDG 491

[Close]

BLAST of One cut domain family member vs. Ensembl Medaka
Match: onecut1 (one cut homeobox 1 [Source:NCBI gene;Acc:101168774])

HSP 1 Score: 259.996 bits (663), Expect = 1.793e-77
Identity = 123/167 (73.65%), Postives = 145/167 (86.83%), Query Frame = 1

Query: 1000 QIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA-EISVN-KRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDEN 1494
            Q++E+NT+E++QRI++ELKRYSIPQAIFAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA E S+  KRKE +  + +     KK RLVFT++QRRTL AIF+E KRPSK +Q TIAQQLGL ++TV+NFFMNARRRS+DKW D+ 
Sbjct:  274 QMEEVNTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAGERSLACKRKEQDHGRSERGNVTKKPRLVFTDVQRRTLHAIFKENKRPSKELQLTIAQQLGLELATVSNFFMNARRRSLDKWVDDG 440

[Close]

BLAST of One cut domain family member vs. Ensembl Medaka
Match: onecut3b (hepatocyte nuclear factor 6 [Source:NCBI gene;Acc:101171777])

HSP 1 Score: 260.381 bits (664), Expect = 2.310e-77
Identity = 124/171 (72.51%), Postives = 149/171 (87.13%), Query Frame = 1

Query:  994 DMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHSI 1506
            ++Q +EINT+E++QRI++ELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLA     KRKE+++ + +   P KKQRLVFT++QRRTL+AIF+E +RPSK MQ TI+QQLGL +STV+NFFMN+RRR  D+W D   H++
Sbjct:  275 NIQAEEINTKEVAQRITAELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC---KRKEEDRGRERSQVP-KKQRLVFTDLQRRTLVAIFRENRRPSKEMQLTISQQLGLELSTVSNFFMNSRRRCPDRW-DTEEHAV 440

[Close]

BLAST of One cut domain family member vs. Planmine SMEST
Match: SMESG000011334.1 (SMESG000011334.1)

HSP 1 Score: 1044.65 bits (2700), Expect = 0.000e+0
Identity = 595/612 (97.22%), Postives = 598/612 (97.71%), Query Frame = 1

Query:  745 PGYLPPQFRGIQGTNVNMAGQNYMYSANGNGENDIKPDLKTLIPGLPGMGXXXXXXXXXXXXFNVHGMMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHSITMESMSPTNSPSSAGVMVGTAPGTVSNTHLKCRNLSMDSDNNVHPYSKNLHNEETNVEDLQKTIPDDSCENXXXXXXXXXXXXXXXXXXXXXHNVEQNSTSCYDENDQMNLNVNLLNSQGLSQPPPLATXXXXXXXXXXXXXXXAQYPSAQMHHFSQQAMXXXXXXXXXXXXXFPGGPLLGMPFNPNMPQNTNPNHXXXXXXXXXXXXXXXTQSHPLINQYMMENGSRSGTPLESFADTFQNQSLQPQYIMTSQGVEIMTKPLLINENECQKGDMDSECESIGRNKIFTNKINPILGKSKKIIKVNDLTVEENIKESEQNYCEVSIESNVLSKIEKPSHSPGNESKDIPDSTSETEKV 2580
            PGYLPPQFRGIQGTNVNMAGQNYMYSANGNGENDIKPDLKTLIPGLPGMGPPELHHPHLSHPFNVHGMMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHSITMESMSPTNSPSSAGVMVGTAPGTVSNTHLKCRNLSMDSDNNVHPYSKNLHNEETNV+DLQKTIPDDSCENMQAELQQASQSMAESMSEMMMHNVEQNSTSCYDENDQMNLNVNLLNSQGLSQPPPLATHHHLNHLHHLYQQHLAQYPSAQMHHFSQQAMYRQPLPQYQYRQYFPGGPLLGMPFNPNMPQNTNPNHAASFSFPRFASSPLSTQSHPLINQYM+ENGSRSGTPLESFADTFQNQSLQPQYIMTSQGVEIMTKPLLINENECQKGDMDSECESI              GKS+KIIKVNDLTVEENIKESEQNYCEVSIESNVLSKIEKPSHSPGNESKDIPDSTSETEKV
Sbjct:   32 PGYLPPQFRGIQGTNVNMAGQNYMYSANGNGENDIKPDLKTLIPGLPGMGPPELHHPHLSHPFNVHGMMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHSITMESMSPTNSPSSAGVMVGTAPGTVSNTHLKCRNLSMDSDNNVHPYSKNLHNEETNVDDLQKTIPDDSCENMQAELQQASQSMAESMSEMMMHNVEQNSTSCYDENDQMNLNVNLLNSQGLSQPPPLATHHHLNHLHHLYQQHLAQYPSAQMHHFSQQAMYRQPLPQYQYRQYFPGGPLLGMPFNPNMPQNTNPNHAASFSFPRFASSPLSTQSHPLINQYMIENGSRSGTPLESFADTFQNQSLQPQYIMTSQGVEIMTKPLLINENECQKGDMDSECESI--------------GKSEKIIKVNDLTVEENIKESEQNYCEVSIESNVLSKIEKPSHSPGNESKDIPDSTSETEKV 629

[Close]

BLAST of One cut domain family member vs. Planmine SMEST
Match: SMESG000011334.1 (SMESG000011334.1)

HSP 1 Score: 1037.71 bits (2682), Expect = 0.000e+0
Identity = 595/615 (96.75%), Postives = 598/615 (97.24%), Query Frame = 1

Query:  745 PGYLPPQFRGIQGTNVNMAGQNYMYSANGNGENDIKPDLKTLIPG---LPGMGXXXXXXXXXXXXFNVHGMMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHSITMESMSPTNSPSSAGVMVGTAPGTVSNTHLKCRNLSMDSDNNVHPYSKNLHNEETNVEDLQKTIPDDSCENXXXXXXXXXXXXXXXXXXXXXHNVEQNSTSCYDENDQMNLNVNLLNSQGLSQPPPLATXXXXXXXXXXXXXXXAQYPSAQMHHFSQQAMXXXXXXXXXXXXXFPGGPLLGMPFNPNMPQNTNPNHXXXXXXXXXXXXXXXTQSHPLINQYMMENGSRSGTPLESFADTFQNQSLQPQYIMTSQGVEIMTKPLLINENECQKGDMDSECESIGRNKIFTNKINPILGKSKKIIKVNDLTVEENIKESEQNYCEVSIESNVLSKIEKPSHSPGNESKDIPDSTSETEKV 2580
            PGYLPPQFRGIQGTNVNMAGQNYMYSANGNGENDIKPDLKTLIPG   LPGMGPPELHHPHLSHPFNVHGMMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHSITMESMSPTNSPSSAGVMVGTAPGTVSNTHLKCRNLSMDSDNNVHPYSKNLHNEETNV+DLQKTIPDDSCENMQAELQQASQSMAESMSEMMMHNVEQNSTSCYDENDQMNLNVNLLNSQGLSQPPPLATHHHLNHLHHLYQQHLAQYPSAQMHHFSQQAMYRQPLPQYQYRQYFPGGPLLGMPFNPNMPQNTNPNHAASFSFPRFASSPLSTQSHPLINQYM+ENGSRSGTPLESFADTFQNQSLQPQYIMTSQGVEIMTKPLLINENECQKGDMDSECESI              GKS+KIIKVNDLTVEENIKESEQNYCEVSIESNVLSKIEKPSHSPGNESKDIPDSTSETEKV
Sbjct:   24 PGYLPPQFRGIQGTNVNMAGQNYMYSANGNGENDIKPDLKTLIPGFTGLPGMGPPELHHPHLSHPFNVHGMMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDENPHSITMESMSPTNSPSSAGVMVGTAPGTVSNTHLKCRNLSMDSDNNVHPYSKNLHNEETNVDDLQKTIPDDSCENMQAELQQASQSMAESMSEMMMHNVEQNSTSCYDENDQMNLNVNLLNSQGLSQPPPLATHHHLNHLHHLYQQHLAQYPSAQMHHFSQQAMYRQPLPQYQYRQYFPGGPLLGMPFNPNMPQNTNPNHAASFSFPRFASSPLSTQSHPLINQYMIENGSRSGTPLESFADTFQNQSLQPQYIMTSQGVEIMTKPLLINENECQKGDMDSECESI--------------GKSEKIIKVNDLTVEENIKESEQNYCEVSIESNVLSKIEKPSHSPGNESKDIPDSTSETEKV 624

[Close]

BLAST of One cut domain family member vs. Planmine SMEST
Match: SMESG000007728.1 (SMESG000007728.1)

HSP 1 Score: 261.536 bits (667), Expect = 5.544e-76
Identity = 134/241 (55.60%), Postives = 167/241 (69.29%), Query Frame = 1

Query:  787 NVNMAGQNYMYSANGN-----GENDIKPDLKTLIPGL-PGMGXXXXXXXXXXXXFNVHGMMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            N+++  +++  S+N N      +NDIKPD+K    G               +   N++ +  ++ M+             ++NT++L+QRIS+ELKRYSIPQA+FAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRM KWL EPE  RM++LR A     KRK+D    P+E K  KK RLVFT+IQRRTL AIF+ETKRPSK MQ TIAQQL L VSTVANFFMNARRRS+DKWQ++
Sbjct:  174 NIDIVSRDFSMSSNMNCIDLENDNDIKPDIKNFGEGWNETSASENTASNCGNDEDNINDLSDNADME-------------DLNTKDLAQRISAELKRYSIPQAVFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMCKWLNEPEAYRMASLRTA--IAGKRKDDLPKTPEEQKQSKKPRLVFTDIQRRTLHAIFKETKRPSKEMQTTIAQQLNLDVSTVANFFMNARRRSVDKWQED 399

[Close]

BLAST of One cut domain family member vs. Planmine SMEST
Match: SMESG000007728.1 (SMESG000007728.1)

HSP 1 Score: 262.692 bits (670), Expect = 6.261e-76
Identity = 134/241 (55.60%), Postives = 167/241 (69.29%), Query Frame = 1

Query:  787 NVNMAGQNYMYSANGN-----GENDIKPDLKTLIPGL-PGMGXXXXXXXXXXXXFNVHGMMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            N+++  +++  S+N N      +NDIKPD+K    G               +   N++ +  ++ M+             ++NT++L+QRIS+ELKRYSIPQA+FAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRM KWL EPE  RM++LR A     KRK+D    P+E K  KK RLVFT+IQRRTL AIF+ETKRPSK MQ TIAQQL L VSTVANFFMNARRRS+DKWQ++
Sbjct:  226 NIDIVSRDFSMSSNMNCIDLENDNDIKPDIKNFGEGWNETSASENTASNCGNDEDNINDLSDNADME-------------DLNTKDLAQRISAELKRYSIPQAVFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMCKWLNEPEAYRMASLRTA---TGKRKDDLPKTPEEQKQSKKPRLVFTDIQRRTLHAIFKETKRPSKEMQTTIAQQLNLDVSTVANFFMNARRRSVDKWQED 450

[Close]

BLAST of One cut domain family member vs. Planmine SMEST
Match: SMESG000007728.1 (SMESG000007728.1)

HSP 1 Score: 261.922 bits (668), Expect = 1.278e-75
Identity = 134/241 (55.60%), Postives = 167/241 (69.29%), Query Frame = 1

Query:  787 NVNMAGQNYMYSANGN-----GENDIKPDLKTLIPGL-PGMGXXXXXXXXXXXXFNVHGMMHHSGMQYNPSQQSLDMQIDEINTRELSQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFTEIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDKWQDE 1491
            N+++  +++  S+N N      +NDIKPD+K    G               +   N++ +  ++ M+             ++NT++L+QRIS+ELKRYSIPQA+FAQR+L RSQGTLSDLLRNPKPWSKLKSGRETFRRM KWL EPE  RM++LR A     KRK+D    P+E K  KK RLVFT+IQRRTL AIF+ETKRPSK MQ TIAQQL L VSTVANFFMNARRRS+DKWQ++
Sbjct:  226 NIDIVSRDFSMSSNMNCIDLENDNDIKPDIKNFGEGWNETSASENTASNCGNDEDNINDLSDNADME-------------DLNTKDLAQRISAELKRYSIPQAVFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMCKWLNEPEAYRMASLRTA--IAGKRKDDLPKTPEEQKQSKKPRLVFTDIQRRTLHAIFKETKRPSKEMQTTIAQQLNLDVSTVANFFMNARRRSVDKWQED 451

The following BLAST results are available for this feature:

BLAST of One cut domain family member vs. Ensembl Human
BLAST of One cut domain family member vs. Ensembl Celegans
BLAST of One cut domain family member vs. Ensembl Fly
BLAST of One cut domain family member vs. Ensembl Zebrafish
BLAST of One cut domain family member vs. Ensembl Xenopus
BLAST of One cut domain family member vs. Ensembl Mouse
BLAST of One cut domain family member vs. UniProt/SwissProt
BLAST of One cut domain family member vs. TrEMBL
BLAST of One cut domain family member vs. Ensembl Cavefish
BLAST of One cut domain family member vs. Ensembl Sea Lamprey
BLAST of One cut domain family member vs. Ensembl Yeast
BLAST of One cut domain family member vs. Ensembl Nematostella
BLAST of One cut domain family member vs. Ensembl Medaka
BLAST of One cut domain family member vs. Planmine SMEST

BLAST of One cut domain family member vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ONECUT1	1.750e-78	77.44	one cut homeobox 1 [Source:HGNC Symbol;Acc:HGNC:81...	[more]
ONECUT3	2.207e-76	76.54	one cut homeobox 3 [Source:NCBI gene;Acc:390874]	[more]
ONECUT2	3.142e-76	73.68	one cut homeobox 2 [Source:HGNC Symbol;Acc:HGNC:81...	[more]
ONECUT1	2.327e-31	87.50	one cut homeobox 1 [Source:HGNC Symbol;Acc:HGNC:81...	[more]
CUX1	3.810e-14	32.18	cut like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2...	[more]

BLAST of One cut domain family member vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ceh-48	3.977e-66	71.60	One cut domain family member [Source:UniProtKB/Tr...	[more]
ceh-38	2.529e-50	57.83	Homeobox protein ceh-38 [Source:UniProtKB/Swiss-P...	[more]
ceh-38	2.932e-50	57.83	Homeobox protein ceh-38 [Source:UniProtKB/Swiss-P...	[more]
ceh-38	2.933e-50	57.83	Homeobox protein ceh-38 [Source:UniProtKB/Swiss-P...	[more]
ceh-38	3.224e-50	57.83	Homeobox protein ceh-38 [Source:UniProtKB/Swiss-P...	[more]

BLAST of One cut domain family member vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
onecut	8.013e-40	71.96	gene:FBgn0028996 transcript:FBtr0089104	[more]
onecut	8.013e-40	71.96	gene:FBgn0028996 transcript:FBtr0310610	[more]
ct	6.106e-15	28.10	gene:FBgn0004198 transcript:FBtr0071068	[more]
ct	6.316e-15	28.10	gene:FBgn0004198 transcript:FBtr0331733	[more]
ct	8.494e-15	28.10	gene:FBgn0004198 transcript:FBtr0305134	[more]

BLAST of One cut domain family member vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
onecut3b	1.269e-81	77.25	one cut homeobox 3b [Source:ZFIN;Acc:ZDB-GENE-1308...	[more]
onecut3a	2.890e-81	76.51	one cut homeobox 3a [Source:ZFIN;Acc:ZDB-GENE-0502...	[more]
onecut2	2.333e-79	73.08	one cut homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-12021...	[more]
onecut1	9.408e-78	74.39	one cut homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-04042...	[more]
onecut1	2.744e-77	73.49	one cut homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-04042...	[more]

BLAST of One cut domain family member vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSXETT00000038157.1	1.452e-79	74.27	one cut homeobox 3 [Source:NCBI gene;Acc:100491290...	[more]
onecut1	1.044e-78	77.44	one cut homeobox 1 [Source:NCBI gene;Acc:100101763...	[more]
mgll	1.488e-76	66.49	monoglyceride lipase [Source:Xenbase;Acc:XB-GENE-9...	[more]
ONECUT2	5.292e-76	75.61	one cut homeobox 2 [Source:NCBI gene;Acc:100485320...	[more]
ONECUT2	4.637e-75	73.68	one cut homeobox 2 [Source:NCBI gene;Acc:100485320...	[more]

BLAST of One cut domain family member vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Onecut1	5.338e-79	77.44	one cut domain, family member 1 [Source:MGI Symbol...	[more]
Onecut3	1.378e-76	76.54	one cut domain, family member 3 [Source:MGI Symbol...	[more]
Onecut2	2.019e-76	73.68	one cut domain, family member 2 [Source:MGI Symbol...	[more]
Cux1	2.742e-14	31.77	cut-like homeobox 1 [Source:MGI Symbol;Acc:MGI:885...	[more]
Cux1	3.533e-14	31.77	cut-like homeobox 1 [Source:MGI Symbol;Acc:MGI:885...	[more]

BLAST of One cut domain family member vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O08755\|HNF6_MOUSE	3.734e-78	77.44	Hepatocyte nuclear factor 6 OS=Mus musculus OX=100...	[more]
sp\|P70512\|HNF6_RAT	4.180e-78	77.44	Hepatocyte nuclear factor 6 OS=Rattus norvegicus O...	[more]
sp\|Q9UBC0\|HNF6_HUMAN	8.406e-78	77.44	Hepatocyte nuclear factor 6 OS=Homo sapiens OX=960...	[more]
sp\|Q8K557\|ONEC3_MOUSE	9.636e-76	76.54	One cut domain family member 3 OS=Mus musculus OX=...	[more]
sp\|O60422\|ONEC3_HUMAN	1.060e-75	76.54	One cut domain family member 3 OS=Homo sapiens OX=...	[more]

BLAST of One cut domain family member vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3J3A5	3.383e-81	75.00	One cut domain family member OS=Lingula unguis OX=...	[more]
A0A4W4FMU2	4.135e-81	77.98	One cut domain family member OS=Electrophorus elec...	[more]
A0A1S3J4Y3	7.475e-81	75.00	One cut domain family member OS=Lingula unguis OX=...	[more]
A0A2C9K7Y3	4.739e-80	72.92	One cut domain family member OS=Biomphalaria glabr...	[more]
V4CJP9	9.718e-79	76.11	One cut domain family member OS=Lottia gigantea OX...	[more]

BLAST of One cut domain family member vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
onecut3b	4.737e-82	78.05	one cut domain family member 3-like [Source:NCBI g...	[more]
ENSAMXT00000055666.1	1.106e-80	77.25	one cut domain family member 3-like [Source:NCBI g...	[more]
onecut2	1.110e-78	77.30	one cut homeobox 2 [Source:NCBI gene;Acc:103028667...	[more]
onecut1	2.707e-77	74.25	one cut homeobox 1 [Source:NCBI gene;Acc:103047808...	[more]
onecutl	3.811e-70	69.14	hepatocyte nuclear factor 6-like [Source:NCBI gene...	[more]

BLAST of One cut domain family member vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
onecut3a	2.246e-45	90.12	one cut homeobox 3a [Source:ZFIN;Acc:ZDB-GENE-0502...	[more]

BLAST of One cut domain family member vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of One cut domain family member vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO45004	1.055e-46	52.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36708	9.031e-12	28.93	Onecut-like protein; Predicted protein [Source:Un...	[more]

BLAST of One cut domain family member vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
onecut3a	3.033e-80	77.30	one cut domain family member 2 [Source:NCBI gene;A...	[more]
onecut2	1.090e-78	75.15	one cut homeobox 2 [Source:NCBI gene;Acc:101162148...	[more]
onecut2	1.288e-78	75.15	one cut homeobox 2 [Source:NCBI gene;Acc:101162148...	[more]
onecut1	1.793e-77	73.65	one cut homeobox 1 [Source:NCBI gene;Acc:101168774...	[more]
onecut3b	2.310e-77	72.51	hepatocyte nuclear factor 6 [Source:NCBI gene;Acc:...	[more]

BLAST of One cut domain family member vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000011334.1	0.000e+0	97.22	SMESG000011334.1	[more]
SMESG000011334.1	0.000e+0	96.75	SMESG000011334.1	[more]
SMESG000007728.1	5.544e-76	55.60	SMESG000007728.1	[more]
SMESG000007728.1	6.261e-76	55.60	SMESG000007728.1	[more]
SMESG000007728.1	1.278e-75	55.60	SMESG000007728.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30007624 ID=SMED30007624|Name=One cut domain family member|organism=Schmidtea mediterranea sexual|type=transcript|length=2671bp
ATTTGAAATTTCAAATAAATCAATATGAAATTTTAGCATTAATTTTCGGG
TATTTTTATTGAAACTGAATGCGTATTGAAGTTTATTTCTTATCAATTAA
ATTACAATAATTTATAATAAAAATTATTCATGAGCTCGTCGACCAACAGT
ATTGACAAGCAGCAAAATAAAAAAATCCAAGAAACTTATTCACAATCCGA
AATGTTGAATTTGTCGAGCATGAGCAATCCGTCGATTAAATATGAATACG
ATGAAAATTATTCTCGGGAAATCGAAGATGAAGATATTGAAACGGAAAAG
TCAATTGTGTCTGAACAACAGAGTATGAGAGAAGAAGTTGACGAAGATGA
GTTGGGGAACTCATGCAATCCTCAAGGTAAGCTCAACATGGAAATGTCTG
CGTCAGACGGGCCTACTATTAACGATTATCCAAATGCATCCTATGCTAAT
GCCGGCTGTGAAAATGGTTACAATTTTACCGGGACTGGAATGATTAATGG
CGCCGTCAATCCTGAGGAGTTAATAATGGATCCGAATGCGCAAATGTTTA
ATGGAGGTACACTCGGAGGACTTCCTTTGCCACCGCATTGTAATTATTTG
GCTAATTCATTTGGCGCTGGTGGCTATTTTTATACCGATGCCGAATTGCA
AATGGCTGCTGCTCAAAATTATTACATGAATCAGCAAAACATTTACAATA
TGGCTGCAATGGGAAACAATGCCAATCAGAATAATTACTCGATGCCAGGC
TATTTGCCGCCGCAATTCCGAGGTATTCAAGGCACAAACGTCAACATGGC
CGGACAGAATTATATGTATTCGGCTAATGGAAATGGAGAAAATGACATCA
AACCGGACTTGAAAACTTTAATTCCAGGACTTCCGGGAATGGGACCACCG
GAACTTCACCATCCCCATCTTTCTCATCCTTTCAATGTTCATGGAATGAT
GCACCATTCGGGAATGCAATACAATCCTTCTCAGCAGTCGTTAGATATGC
AAATTGACGAGATTAATACGCGAGAATTGTCTCAACGAATCAGTTCCGAG
TTAAAGCGATATAGTATTCCACAGGCAATTTTTGCGCAAAGAATTTTGAG
CCGCAGTCAAGGCACATTGTCAGATTTGTTACGCAATCCGAAGCCTTGGT
CGAAATTGAAATCTGGACGAGAGACATTCCGAAGAATGTGGAAATGGTTG
CAGGAACCTGAATTTCAAAGAATGTCTGCACTAAGACTGGCAGAAATTTC
TGTAAATAAACGTAAAGAAGATGAACAGAGCAAACCTCAAGAAATCAAAC
CGGTCAAAAAGCAGAGACTAGTCTTCACAGAAATTCAAAGACGGACTCTA
ATGGCCATTTTCCAGGAAACAAAAAGACCGAGTAAAGCTATGCAGGCTAC
AATAGCCCAACAACTTGGTCTAGCAGTATCAACTGTAGCAAATTTCTTCA
TGAACGCACGTCGAAGATCAATTGATAAATGGCAAGACGAAAATCCTCAT
AGCATAACAATGGAATCAATGTCTCCAACAAATTCACCATCATCCGCCGG
TGTAATGGTTGGCACAGCTCCAGGTACTGTATCCAATACTCATTTAAAAT
GTCGGAATCTCTCCATGGATTCTGACAATAATGTCCATCCTTACAGTAAA
AATTTGCACAATGAAGAGACCAACGTCGAAGATTTACAAAAGACTATTCC
TGATGATTCCTGTGAAAATATGCAGGCTGAATTGCAGCAAGCAAGCCAAA
GCATGGCTGAGTCGATGTCTGAAATGATGATGCACAATGTCGAACAGAAT
AGCACTAGTTGCTATGACGAGAATGATCAAATGAATTTAAACGTTAATTT
ATTAAACTCACAGGGCTTAAGTCAACCTCCACCTTTAGCAACACATCATC
ATTTAAATCATTTGCATCATCTTTATCAACAGCACCTTGCCCAGTACCCA
TCAGCTCAAATGCACCATTTTTCACAACAAGCAATGTATCGACAGCCACT
TCCTCAATACCAATACAGACAGTATTTCCCGGGTGGTCCATTATTAGGAA
TGCCATTCAACCCAAATATGCCACAAAATACCAACCCAAACCATGCGGCA
TCGTTTTCATTTCCGAGATTTGCATCCAGTCCATTATCTACTCAATCTCA
TCCTTTAATTAATCAGTACATGATGGAAAATGGAAGTCGTTCTGGTACAC
CACTTGAAAGTTTTGCGGATACTTTTCAGAATCAATCTTTACAACCTCAA
TATATTATGACATCGCAAGGAGTGGAAATTATGACTAAACCTCTTCTAAT
TAATGAGAATGAATGTCAAAAAGGGGACATGGACTCAGAATGTGAATCCA
TAGGTAGGAATAAAATATTTACCAATAAGATTAATCCGATTTTAGGGAAA
TCGAAAAAAATAATTAAGGTTAATGATTTGACAGTCGAAGAAAATATAAA
AGAATCAGAACAAAATTATTGTGAGGTCTCAATAGAATCTAATGTCCTCT
CAAAAATAGAAAAGCCTAGCCACAGTCCTGGAAATGAATCCAAAGATATT
CCCGATAGTACATCAGAAACAGAAAAAGTCTAAAATGAAGCTTAGACTCA
GTTTTCATGTAAATTGATGTTTTATTGTTTTGGACGGGTTTCAATGGTAT
GCATGTATATTTTCATAGTTG

protein sequence of SMED30007624-orf-1

>SMED30007624-orf-1 ID=SMED30007624-orf-1|Name=SMED30007624-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=818bp
MSSSTNSIDKQQNKKIQETYSQSEMLNLSSMSNPSIKYEYDENYSREIED
EDIETEKSIVSEQQSMREEVDEDELGNSCNPQGKLNMEMSASDGPTINDY
PNASYANAGCENGYNFTGTGMINGAVNPEELIMDPNAQMFNGGTLGGLPL
PPHCNYLANSFGAGGYFYTDAELQMAAAQNYYMNQQNIYNMAAMGNNANQ
NNYSMPGYLPPQFRGIQGTNVNMAGQNYMYSANGNGENDIKPDLKTLIPG
LPGMGPPELHHPHLSHPFNVHGMMHHSGMQYNPSQQSLDMQIDEINTREL
SQRISSELKRYSIPQAIFAQRILSRSQGTLSDLLRNPKPWSKLKSGRETF
RRMWKWLQEPEFQRMSALRLAEISVNKRKEDEQSKPQEIKPVKKQRLVFT
EIQRRTLMAIFQETKRPSKAMQATIAQQLGLAVSTVANFFMNARRRSIDK
WQDENPHSITMESMSPTNSPSSAGVMVGTAPGTVSNTHLKCRNLSMDSDN
NVHPYSKNLHNEETNVEDLQKTIPDDSCENMQAELQQASQSMAESMSEMM
MHNVEQNSTSCYDENDQMNLNVNLLNSQGLSQPPPLATHHHLNHLHHLYQ
QHLAQYPSAQMHHFSQQAMYRQPLPQYQYRQYFPGGPLLGMPFNPNMPQN
TNPNHAASFSFPRFASSPLSTQSHPLINQYMMENGSRSGTPLESFADTFQ
NQSLQPQYIMTSQGVEIMTKPLLINENECQKGDMDSECESIGRNKIFTNK
INPILGKSKKIIKVNDLTVEENIKESEQNYCEVSIESNVLSKIEKPSHSP
GNESKDIPDSTSETEKV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000419	prepharyngeal region

Vocabulary: **INTERPRO**
Term	Definition
IPR003350	CUT_dom
IPR001356	Homeobox_dom
IPR010982	Lambda_DNA-bd_dom_sf
IPR009057	Homeobox-like_sf

Vocabulary: **molecular function**
Term	Definition
GO:0003677	DNA binding
GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

Vocabulary: **biological process**
Term	Definition
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0030154	cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048731	system development

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 354..374
None	No IPR available	GENE3D	G3DSA:1.10.10.60		coord: 197..270 e-value: 1.8E-23 score: 84.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 618..643
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 624..643
None	No IPR available	PANTHER	PTHR14057:SF34	ONE CUT DOMAIN FAMILY MEMBER 3	coord: 59..290
None	No IPR available	PANTHER	PTHR14057	TRANSCRIPTION FACTOR ONECUT	coord: 59..290
IPR003350	CUT domain	SMART	SM01109	CUT_2	coord: 113..198 e-value: 2.5E-40 score: 150.0
IPR003350	CUT domain	PFAM	PF02376	CUT	coord: 119..193 e-value: 6.1E-30 score: 103.2
IPR003350	CUT domain	PROSITE	PS51042	CUT	coord: 112..198 score: 29.889
IPR001356	Homeobox domain	SMART	SM00389	HOX_1	coord: 218..280 e-value: 9.3E-12 score: 55.1
IPR001356	Homeobox domain	PFAM	PF00046	Homeodomain	coord: 219..272 e-value: 3.0E-10 score: 39.8
IPR001356	Homeobox domain	PROSITE	PS50071	HOMEOBOX_2	coord: 216..276 score: 11.612
IPR001356	Homeobox domain	CDD	cd00086	homeodomain	coord: 219..273 e-value: 8.68042E-11 score: 55.7125
IPR010982	Lambda repressor-like, DNA-binding domain superfamily	GENE3D	G3DSA:1.10.260.40		coord: 118..196 e-value: 6.2E-38 score: 130.6
IPR010982	Lambda repressor-like, DNA-binding domain superfamily	SUPERFAMILY	SSF47413	lambda repressor-like DNA-binding domains	coord: 99..197
IPR009057	Homeobox-like domain superfamily	SUPERFAMILY	SSF46689	Homeodomain-like	coord: 219..284

Main menu

One cut domain family member

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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