Adenylate kinase

Overview
NameAdenylate kinase
Smed IDSMED30007623
Length (bp)815
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Adenylate kinase (SMED30007623) t-SNE clustered cells

Violin plots show distribution of expression levels for Adenylate kinase (SMED30007623) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30007623

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30007623h1SMcG0017360 SmedASXL_009231SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
prepharyngeal regionSMED30007623h1SMcG0017359 SmedASXL_009231SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30007623h1SMcG0017360 Contig18481newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30007623h1SMcG0017360 Contig18481uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30007623h1SMcG0017361 Contig18481newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30007623h1SMcG0017361 Contig18481uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Adenylate kinase vs. Ensembl Human
Match: AK5 (adenylate kinase 5 [Source:HGNC Symbol;Acc:HGNC:365])

HSP 1 Score: 77.0258 bits (188), Expect = 2.411e-15
Identity = 66/293 (22.53%), Postives = 130/293 (44.37%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSE-LKDLNCIQG-------------------------LFQYQTLSDKN-SCKGDISNDF----------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDP----YETSRKLANYKAYTLPVLKYFED 793
            +YL    I +LFE+L + L+ S+P D +++L+  L+ VK   G ++ K+D F S   + L  LN  Q                          + Q+   SD + S   ++  ++          K+IL+I  PG      ++         Y+++G+ LRK++   S     +W +   ++  G+L P++  +  +  ++  + ++E I+I+G+PR+  Q    ++ I    ++ VF+       C    L     +  + +  P      T R+L N+K    P++KYF++
Sbjct:    8 EYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLV-VFLA------CANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQE 291

HSP 2 Score: 55.4546 bits (132), Expect = 4.113e-8
Identity = 46/175 (26.29%), Postives = 79/175 (45.14%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLAN----YKAYTLPVLKYFEDNQKL 805
            K+I +I  PG     G     L    G+ ++  G+ LR+ +  ES+    R K+ + +M  GDLVP  I L +L +  +  L +    +I+GYPR   Q ++    IG +  L + M      DC    +     +   S     +T++ +A     Y   ++PV+ Y+E   +L
Sbjct:  377 KIIFIIGGPGSGK--GTQCEKLVEKYGFTHLSTGELLREELASESE----RSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIG-DPQLVICM------DCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQL 538
[Close]
BLAST of Adenylate kinase vs. Ensembl Human
Match: AK5 (adenylate kinase 5 [Source:HGNC Symbol;Acc:HGNC:365])

HSP 1 Score: 62.003 bits (149), Expect = 2.749e-10
Identity = 58/274 (21.17%), Postives = 118/274 (43.07%), Query Frame = 2 
Query:   98 LLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSE-LKDLNCIQG-------------------------LFQYQTLSDKN-SCKGDISNDF----------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDP----YETSRKLANYKAYTLPVLKYFED 793
            + S+P D +++L+  L+ VK   G ++ K+D F S   + L  LN  Q                          + Q+   SD + S   ++  ++          K+IL+I  PG      ++         Y+++G+ LRK++   S     +W +   ++  G+L P++  +  +  ++  + ++E I+I+G+PR+  Q    ++ I    ++ VF+       C    L     +  + +  P      T R+L N+K    P++KYF++
Sbjct:    1 MCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLV-VFLA------CANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQE 265

HSP 2 Score: 55.4546 bits (132), Expect = 3.549e-8
Identity = 46/175 (26.29%), Postives = 79/175 (45.14%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLAN----YKAYTLPVLKYFEDNQKL 805
            K+I +I  PG     G     L    G+ ++  G+ LR+ +  ES+    R K+ + +M  GDLVP  I L +L +  +  L +    +I+GYPR   Q ++    IG +  L + M      DC    +     +   S     +T++ +A     Y   ++PV+ Y+E   +L
Sbjct:  351 KIIFIIGGPGSGK--GTQCEKLVEKYGFTHLSTGELLREELASESE----RSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIG-DPQLVICM------DCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQL 512
[Close]
BLAST of Adenylate kinase vs. Ensembl Human
Match: AK1 (adenylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:361])

HSP 1 Score: 50.0618 bits (118), Expect = 7.411e-7
Identity = 45/167 (26.95%), Postives = 72/167 (43.11%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCN-KELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYET-SRKLANYKAYTLPVLKYFE 790
            K+I ++  PG     G     +    GY ++  GD LR  V      G +R K    +M  G LVP +  L +L D +    N  +  +I+GYPR   Q ++ +  IG   +L    +D+        LL   +   +    D  ET  ++L  Y   T PV+ ++E
Sbjct:    9 KIIFVVGGPGSGK--GTQCEKIVQKYGYTHLSTGDLLRSEVSS----GSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLL--LYVDAGPETMTQRLLKRGETSGRVD--DNEETIKKRLETYYKATEPVIAFYE 165
[Close]
BLAST of Adenylate kinase vs. Ensembl Human
Match: AK1 (adenylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:361])

HSP 1 Score: 50.0618 bits (118), Expect = 7.411e-7
Identity = 45/167 (26.95%), Postives = 72/167 (43.11%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCN-KELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYET-SRKLANYKAYTLPVLKYFE 790
            K+I ++  PG     G     +    GY ++  GD LR  V      G +R K    +M  G LVP +  L +L D +    N  +  +I+GYPR   Q ++ +  IG   +L    +D+        LL   +   +    D  ET  ++L  Y   T PV+ ++E
Sbjct:    9 KIIFVVGGPGSGK--GTQCEKIVQKYGYTHLSTGDLLRSEVSS----GSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLL--LYVDAGPETMTQRLLKRGETSGRVD--DNEETIKKRLETYYKATEPVIAFYE 165
[Close]
BLAST of Adenylate kinase vs. Ensembl Human
Match: AK1 (adenylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:361])

HSP 1 Score: 49.6766 bits (117), Expect = 1.123e-6
Identity = 45/167 (26.95%), Postives = 72/167 (43.11%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCN-KELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYET-SRKLANYKAYTLPVLKYFE 790
            K+I ++  PG     G     +    GY ++  GD LR  V      G +R K    +M  G LVP +  L +L D +    N  +  +I+GYPR   Q ++ +  IG   +L    +D+        LL   +   +    D  ET  ++L  Y   T PV+ ++E
Sbjct:   25 KIIFVVGGPGSGK--GTQCEKIVQKYGYTHLSTGDLLRSEVSS----GSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLL--LYVDAGPETMTQRLLKRGETSGRVD--DNEETIKKRLETYYKATEPVIAFYE 181
[Close]
BLAST of Adenylate kinase vs. Ensembl Celegans
Match: F13E6.2 (pep chromosome:WBcel235:X:10668280:10674293:-1 gene:WBGene00008746.1 transcript:F13E6.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F13E6.2)

HSP 1 Score: 80.1073 bits (196), Expect = 9.396e-17
Identity = 59/179 (32.96%), Postives = 97/179 (54.19%), Query Frame = 2 
Query:  287 ISNDFKVILLISAPG-EPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRW-KVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKEL-IIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII 814
            + N+  VIL++ APG + + I   ++  Y+    ++MGD LRK++  E  K    W KVSK  MNNGD +P  +   VL +E+          +IEGYP++ +Q+ DL+++  L+R     +ID  E  C   ++N  +  NK S+ D      ++  +K  TLP+LK  +D  KL ++
Sbjct:  509 LPNNAPVILVLGAPGSQKNDISRRIAQKYDGFTMLSMGDILRKKINNE--KNDEMWDKVSKK-MNNGDPIPTKMCRTVLYEELHSRGTSNWGYVIEGYPKSPDQLVDLEHS--LQRTDLAILIDCTEQFC-LEVINKRNRENKRSDDDSDAVRSRMEYFKKNTLPMLKTLDDKGKLRVV 681

HSP 2 Score: 51.2174 bits (121), Expect = 4.064e-7
Identity = 46/178 (25.84%), Postives = 83/178 (46.63%), Query Frame = 2 
Query:  296 DFKVILLISAPG-----EPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII 814
            D  +IL +  PG        ++ + L++  N + ++ M D +R  + K   K    WK +      G+L+P  +AL +L  E+    +     +EGYPR   Q++D +  +   + +++ +I   + D RT L    + R    E       +K+  +K  TLP  KYF+D + L +I
Sbjct:  168 DVPIILFMGGPGGGKTRHAARVADSLAD--NGLVHICMPDIIRTALGKYKDK-YPEWKEANEHYIRGELIPNQLALTLLKAEMGRHPDAMGFFLEGYPREARQVEDFERQV---KSVNMALI--LDYDERT-LREHMERRGLGMEI----IDQKIKEFKQKTLPSAKYFDDQKLLHLI 332
[Close]
BLAST of Adenylate kinase vs. Ensembl Celegans
Match: F40F8.1 (UMP-CMP kinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20230])

HSP 1 Score: 57.3806 bits (137), Expect = 1.361e-9
Identity = 45/183 (24.59%), Postives = 88/183 (48.09%), Query Frame = 2 
Query:  251 QTLSDKNSCKGDISNDFKVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAI-GLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFE 790
            Q++S     + D+ N   V+ ++  PG     G I + +  N+ YV++  GD LR   Q+E   G     + +S + NG +VP +I   +L + +K   + +  +++G+PRNE+ ++  +  + G   +  V  +    + C    LN    R  D+E       +++  Y   T P++++FE
Sbjct:   26 QSVSFGTLTRNDMHN---VVFVLGPPGSGK--GTICAKIQENLNYVHLSAGDLLRAERQRE---GSEFGALIESHIKNGSIVPVEITCSLLENAMKACGDAKGFLVDGFPRNEDNLQGWNKQMDGKALVQFVLFLSCPVSICIERCLNRGQGRTDDNE---ESLKKRVETYNQQTFPIIEHFE 197
[Close]
BLAST of Adenylate kinase vs. Ensembl Celegans
Match: F40F8.1 (UMP-CMP kinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20230])

HSP 1 Score: 56.6102 bits (135), Expect = 1.362e-9
Identity = 41/165 (24.85%), Postives = 80/165 (48.48%), Query Frame = 2 
Query:  305 VILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAI-GLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFE 790
            V+ ++  PG     G I + +  N+ YV++  GD LR   Q+E   G     + +S + NG +VP +I   +L + +K   + +  +++G+PRNE+ ++  +  + G   +  V  +    + C    LN    R  D+E       +++  Y   T P++++FE
Sbjct:    4 VVFVLGPPGSGK--GTICAKIQENLNYVHLSAGDLLRAERQRE---GSEFGALIESHIKNGSIVPVEITCSLLENAMKACGDAKGFLVDGFPRNEDNLQGWNKQMDGKALVQFVLFLSCPVSICIERCLNRGQGRTDDNE---ESLKKRVETYNQQTFPIIEHFE 160
[Close]
BLAST of Adenylate kinase vs. Ensembl Celegans
Match: F40F8.1 (UMP-CMP kinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20230])

HSP 1 Score: 56.6102 bits (135), Expect = 1.362e-9
Identity = 41/165 (24.85%), Postives = 80/165 (48.48%), Query Frame = 2 
Query:  305 VILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAI-GLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFE 790
            V+ ++  PG     G I + +  N+ YV++  GD LR   Q+E   G     + +S + NG +VP +I   +L + +K   + +  +++G+PRNE+ ++  +  + G   +  V  +    + C    LN    R  D+E       +++  Y   T P++++FE
Sbjct:    4 VVFVLGPPGSGK--GTICAKIQENLNYVHLSAGDLLRAERQRE---GSEFGALIESHIKNGSIVPVEITCSLLENAMKACGDAKGFLVDGFPRNEDNLQGWNKQMDGKALVQFVLFLSCPVSICIERCLNRGQGRTDDNE---ESLKKRVETYNQQTFPIIEHFE 160
[Close]
BLAST of Adenylate kinase vs. Ensembl Celegans
Match: F40F8.1 (UMP-CMP kinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20230])

HSP 1 Score: 56.6102 bits (135), Expect = 1.362e-9
Identity = 41/165 (24.85%), Postives = 80/165 (48.48%), Query Frame = 2 
Query:  305 VILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAI-GLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFE 790
            V+ ++  PG     G I + +  N+ YV++  GD LR   Q+E   G     + +S + NG +VP +I   +L + +K   + +  +++G+PRNE+ ++  +  + G   +  V  +    + C    LN    R  D+E       +++  Y   T P++++FE
Sbjct:    4 VVFVLGPPGSGK--GTICAKIQENLNYVHLSAGDLLRAERQRE---GSEFGALIESHIKNGSIVPVEITCSLLENAMKACGDAKGFLVDGFPRNEDNLQGWNKQMDGKALVQFVLFLSCPVSICIERCLNRGQGRTDDNE---ESLKKRVETYNQQTFPIIEHFE 160
[Close]
BLAST of Adenylate kinase vs. Ensembl Fly
Match: CG9541 (gene:FBgn0032083 transcript:FBtr0332206)

HSP 1 Score: 48.521 bits (114), Expect = 3.246e-6
Identity = 43/174 (24.71%), Postives = 78/174 (44.83%), Query Frame = 2 
Query:  305 VILLISAPGEPHKIGNILSNLYNNIGY--VNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETS--RKLANYKAYTLPVLKYFEDNQKLTII 814
            +I +I  PG  +K    L  +  N G+  +++G  LR       +     + V ++L   GD+ PE     +L   ++ L ++  II++GYPRN  Q+K  +N               ++      LL+C   +      D   +S  R+L  ++  TLP+LK  + + +L I+
Sbjct:  329 IIWVIGGPGS-NKATLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVKEALAA-GDMAPEKSLNQLLETNLRQLRDRTGIIVDGYPRNLQQVKYFEN--------------KYKQRPPIILLDCSKLQLGRGRIDDTVSSFRRRLELFREQTLPMLKILDTSNRLQIV 486
[Close]
BLAST of Adenylate kinase vs. Ensembl Fly
Match: CG9541 (gene:FBgn0032083 transcript:FBtr0332207)

HSP 1 Score: 48.521 bits (114), Expect = 3.636e-6
Identity = 43/174 (24.71%), Postives = 78/174 (44.83%), Query Frame = 2 
Query:  305 VILLISAPGEPHKIGNILSNLYNNIGY--VNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETS--RKLANYKAYTLPVLKYFEDNQKLTII 814
            +I +I  PG  +K    L  +  N G+  +++G  LR       +     + V ++L   GD+ PE     +L   ++ L ++  II++GYPRN  Q+K  +N               ++      LL+C   +      D   +S  R+L  ++  TLP+LK  + + +L I+
Sbjct:  359 IIWVIGGPGS-NKATLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVKEALAA-GDMAPEKSLNQLLETNLRQLRDRTGIIVDGYPRNLQQVKYFEN--------------KYKQRPPIILLDCSKLQLGRGRIDDTVSSFRRRLELFREQTLPMLKILDTSNRLQIV 516
[Close]
BLAST of Adenylate kinase vs. Ensembl Zebrafish
Match: ak5 (adenylate kinase 5 [Source:ZFIN;Acc:ZDB-GENE-030131-8256])

HSP 1 Score: 66.6254 bits (161), Expect = 4.486e-12
Identity = 63/291 (21.65%), Postives = 123/291 (42.27%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSELKDLNCIQG-------------------LFQYQTLSDKNSCKGDISNDF--------------------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFED 793
            +YL    I +LFE+L   L+  +P D +++L+  L+ V+   G ++ ++D F  +  E K L  + G                     +Y+ L   N    +  +D                     KVIL+I  PG       +         YV++G+ LRK++   +     +W +   ++ NG+L P++  +  +  +I  +     I+I+G+PR+  Q    ++ +    ++ VF+  S  N      L     +    + +P    R+L N+K   +P++KYF++
Sbjct:    8 EYLSRREIPQLFESLLTGLMYYRPDDPLEYLETCLKKVRDLGGTDKVRWDTF--VGQEKKSLPPLNGGQSRRSFFRNVLPDSPNFPYRRYERLPPINQFSIESDSDLSETAELIEEYEVFDPSRPRPKVILIIGGPGSGKGTQCLKIAERYGFEYVSVGELLRKKMIHNATSN-RKWSLIARIITNGELAPQETTITEIKQKIMKIPEASGIVIDGFPRDVGQALSFEDQVCTPDLV-VFLACS--NQRLKERLEKRAEQQGRPDDNPKAIDRRLTNFKQNAIPLVKYFQE 292
[Close]
BLAST of Adenylate kinase vs. Ensembl Zebrafish
Match: ak1 (adenylate kinase 1 [Source:ZFIN;Acc:ZDB-GENE-040822-37])

HSP 1 Score: 47.3654 bits (111), Expect = 3.850e-6
Identity = 45/168 (26.79%), Postives = 78/168 (46.43%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCN-KELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLAN--YKAYTLPVLKYFE 790
            K++ ++  PG     G     +    GY ++  GD LR  V   S++G    K  +++M  G+LVP D  L ++ D +    +  +  +I+GYPR   Q ++ +  IG   +L    ID+        L+   +   +    D  ET +K  +  YKA T PV+ ++E
Sbjct:    9 KIVFVVGGPGSGK--GTQCEKIVAKYGYTHLSSGDLLRAEVASGSERG----KQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGYLIDGYPREVKQGEEFEKKIGAPALL--LYIDAKGETMVKRLMKRGETSGRAD--DNEETIKKRLDLYYKA-TEPVIAFYE 165
[Close]
BLAST of Adenylate kinase vs. Ensembl Zebrafish
Match: ak1 (adenylate kinase 1 [Source:ZFIN;Acc:ZDB-GENE-040822-37])

HSP 1 Score: 47.3654 bits (111), Expect = 4.480e-6
Identity = 45/168 (26.79%), Postives = 78/168 (46.43%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCN-KELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLAN--YKAYTLPVLKYFE 790
            K++ ++  PG     G     +    GY ++  GD LR  V   S++G    K  +++M  G+LVP D  L ++ D +    +  +  +I+GYPR   Q ++ +  IG   +L    ID+        L+   +   +    D  ET +K  +  YKA T PV+ ++E
Sbjct:    9 KIVFVVGGPGSGK--GTQCEKIVAKYGYTHLSSGDLLRAEVASGSERG----KQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGYLIDGYPREVKQGEEFEKKIGAPALL--LYIDAKGETMVKRLMKRGETSGRAD--DNEETIKKRLDLYYKA-TEPVIAFYE 165
[Close]
BLAST of Adenylate kinase vs. Ensembl Xenopus
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:100127649])

HSP 1 Score: 67.3958 bits (163), Expect = 4.040e-12
Identity = 62/293 (21.16%), Postives = 126/293 (43.00%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSE-LKDLNCIQG-------------------------LFQYQTLSDKN-SCKGDISNDF----------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDP----YETSRKLANYKAYTLPVLKYFED 793
            +YL    I +LFE L + L+  +P D + +L++ L+ VK   G E+ ++D F   +   L  LN  Q                          + Q+   SD + S   ++  ++          K+IL+I  PG      ++         Y+++G+ LRK++   S     +W +   ++  G+L P++  +  +  ++  + + E I+I+G+PR+  Q    ++ I    ++ VF+       C +  L     +  + +  P        R+L N+K   +P++ YF++
Sbjct:    8 EYLARREIPQLFEGLLNGLMYYRPDDPVDYLENCLQKVKELGGTEKVRWDTFVGPDKRNLPPLNGGQARRSFFRNVMPDGGNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPSRPHPKIILVIGGPGSGKGTQSLKIAERYGFEYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQIPDSEGIVIDGFPRDVAQALSFEDQICTPDLV-VFLA------CASHKLKERLQKRAEQQGRPDDNLKAIQRRLMNFKQNAVPLVNYFQE 291
[Close]
BLAST of Adenylate kinase vs. Ensembl Xenopus
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:448536])

HSP 1 Score: 63.5438 bits (153), Expect = 5.497e-11
Identity = 63/287 (21.95%), Postives = 116/287 (40.42%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMN------------------------SELKDLNCIQGLFQYQTLSDKNSCKGDISN---------DFKVILLISAPGEPHKIGNILSNLYNNIGY--VNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFED 793
            DYL   +I  LFE+L   L+  +P D I +++  L+ V+   G E+ ++D F S N                           + L  IQ  F   + SD     G I             K+I +I  PG     G   + + ++ G+  V++GD LRK++   +     +W++   +++ GDL P +  +  L  +     +    +++G+PR+  Q    +  IG   ++      S     R         R  D+    +   R+L+ +K     ++KY++D
Sbjct:    8 DYLTDRHIPRLFESLLTGLMYYRPEDPISYMEMCLQKVRDIGGPEKVQWDTFLSRNLPPINGGQGKKTPHRAEGLPAPQMRRYERLPPIQSQFSIDSDSDMTESSGLIQEYDVFDPNRERPKIIFVIGGPGS--GKGTQSTKMASHFGFICVSVGDILRKQLIHHASSD-RKWELIAQIISKGDLAPPETTIEELKQQFINHQDATGFVVDGFPRDIGQAFTFEEQIGSPDLVIFLACSSQRLRQRLERRASLHGRPDDNA---HAIDRRLSTFKQNLPLIVKYYQD 288
[Close]
BLAST of Adenylate kinase vs. Ensembl Xenopus
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:100127649])

HSP 1 Score: 54.299 bits (129), Expect = 7.322e-8
Identity = 36/168 (21.43%), Postives = 79/168 (47.02%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDP----YETSRKLANYKAYTLPVLKYFED 793
            K+IL+I  PG      ++         Y+++G+ LRK++   S     +W +   ++  G+L P++  +  +  ++  + + E I+I+G+PR+  Q    ++ I    ++ VF+       C +  L     +  + +  P        R+L N+K   +P++ YF++
Sbjct:   50 KIILVIGGPGSGKGTQSLKIAERYGFEYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQIPDSEGIVIDGFPRDVAQALSFEDQICTPDLV-VFLA------CASHKLKERLQKRAEQQGRPDDNLKAIQRRLMNFKQNAVPLVNYFQE 208
[Close]
BLAST of Adenylate kinase vs. Ensembl Xenopus
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:448536])

HSP 1 Score: 48.521 bits (114), Expect = 2.046e-6
Identity = 43/166 (25.90%), Postives = 75/166 (45.18%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFE 790
            K+I ++  PG     G     + +  GY ++  GD LR  V   S++G    K   ++M  G+LVP D  L +L +  I      +  +I+GYPR   Q ++ +  IG   +L    ID+  +     LL   +   + ++ +     ++L  Y   T PV+  +E
Sbjct:    9 KIIFVVGGPGSGK--GTQCEKIVHQYGYTHLSTGDLLRAEVSSGSERG----KHLSAIMEKGELVPLDTVLDMLKEAMIAKADTSKGYLIDGYPREVKQGEEFEKKIGPPSLL--LYIDAGSDTMVKRLLKRGETSGR-ADDNEATIKKRLETYYKATEPVIAMYE 165
[Close]
BLAST of Adenylate kinase vs. Ensembl Xenopus
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:448536])

HSP 1 Score: 48.9062 bits (115), Expect = 2.266e-6
Identity = 46/168 (27.38%), Postives = 75/168 (44.64%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDF--RNKDSEFDPYETSRKLANYKAYTLPVLKYFE 790
            K+I ++  PG     G     + +  GY ++  GD LR  V   S++G    K   ++M  G+LVP D  L +L +  I      +  +I+GYPR   Q ++ +  IG   +L    ID+  +     LL   +   R  D+E       ++L  Y   T PV+  +E
Sbjct:   54 KIIFVVGGPGSGK--GTQCEKIVHQYGYTHLSTGDLLRAEVSSGSERG----KHLSAIMEKGELVPLDTVLDMLKEAMIAKADTSKGYLIDGYPREVKQGEEFEKKIGPPSLL--LYIDAGSDTMVKRLLKRGETSGRADDNEAT---IKKRLETYYKATEPVIAMYE 210
[Close]
BLAST of Adenylate kinase vs. Ensembl Mouse
Match: Ak5 (adenylate kinase 5 [Source:MGI Symbol;Acc:MGI:2677491])

HSP 1 Score: 78.9518 bits (193), Expect = 4.062e-16
Identity = 68/293 (23.21%), Postives = 132/293 (45.05%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSE-LKDLNCIQG-------------------------LFQYQTLSDKN-SCKGDISNDF----------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDP----YETSRKLANYKAYTLPVLKYFED 793
            +YL   +I +LFE+L + L+ S+P D I++L+  L+ VK   G ++ K+D F S   + L  LN  Q                          + Q+   SD + S   ++  ++          K+IL+I  PG      ++         Y+++G+ LRK++   S     +W +   ++ NG+L P++  +  +  ++  + ++E I+I+G+PR+  Q    ++ I    ++ VF+       C    L     +  + +  P      T R+L N+K    P++KYF++
Sbjct:    8 EYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSN--RKWSLIAKIITNGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLV-VFLA------CANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQE 291

HSP 2 Score: 57.7658 bits (138), Expect = 4.580e-9
Identity = 45/171 (26.32%), Postives = 78/171 (45.61%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKL 805
            K+I L+  PG     G     L    G+ ++  G+ LR+ +  ES+    R K+ + +M  GDLVP  + L +L +  +  L N +  +I+GYPR   Q ++    IG     H+ +      D  T  L      ++  E      +++L  Y   ++PV+ Y+E   +L
Sbjct:  377 KIIFLMGGPGSGK--GTQCEKLAEKYGFTHLSTGELLRQELTSESE----RSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGDP---HLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQL 538
[Close]
BLAST of Adenylate kinase vs. Ensembl Mouse
Match: Ak5 (adenylate kinase 5 [Source:MGI Symbol;Acc:MGI:2677491])

HSP 1 Score: 58.9214 bits (141), Expect = 4.348e-10
Identity = 45/171 (26.32%), Postives = 78/171 (45.61%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKL 805
            K+I L+  PG     G     L    G+ ++  G+ LR+ +  ES+    R K+ + +M  GDLVP  + L +L +  +  L N +  +I+GYPR   Q ++    IG     H+ +      D  T  L      ++  E      +++L  Y   ++PV+ Y+E   +L
Sbjct:   36 KIIFLMGGPGSGK--GTQCEKLAEKYGFTHLSTGELLRQELTSESE----RSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGDP---HLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQL 197
[Close]
BLAST of Adenylate kinase vs. Ensembl Mouse
Match: Ak1 (adenylate kinase 1 [Source:MGI Symbol;Acc:MGI:87977])

HSP 1 Score: 49.2914 bits (116), Expect = 1.070e-6
Identity = 44/167 (26.35%), Postives = 75/167 (44.91%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYET-SRKLANYKAYTLPVLKYFE 790
            K+I ++  PG     G     +    GY ++  GD LR  V   S++G    K   ++M  G+LVP D  L +L D  +  + +    +I+GYPR   Q ++ +  IG   +L    +D+        LL   +   +    D  ET  ++L  Y   T PV+ +++
Sbjct:    9 KIIFVVGGPGSGK--GTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERG----KKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPTLL--LYVDAGAETMTQRLLKRGETSGRVD--DNEETIKKRLETYYNATEPVISFYD 165
[Close]
BLAST of Adenylate kinase vs. Ensembl Mouse
Match: Ak1 (adenylate kinase 1 [Source:MGI Symbol;Acc:MGI:87977])

HSP 1 Score: 49.2914 bits (116), Expect = 1.070e-6
Identity = 44/167 (26.35%), Postives = 75/167 (44.91%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYET-SRKLANYKAYTLPVLKYFE 790
            K+I ++  PG     G     +    GY ++  GD LR  V   S++G    K   ++M  G+LVP D  L +L D  +  + +    +I+GYPR   Q ++ +  IG   +L    +D+        LL   +   +    D  ET  ++L  Y   T PV+ +++
Sbjct:    9 KIIFVVGGPGSGK--GTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERG----KKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPTLL--LYVDAGAETMTQRLLKRGETSGRVD--DNEETIKKRLETYYNATEPVISFYD 165
[Close]
BLAST of Adenylate kinase vs. Ensembl Mouse
Match: Ak1 (adenylate kinase 1 [Source:MGI Symbol;Acc:MGI:87977])

HSP 1 Score: 48.9062 bits (115), Expect = 1.551e-6
Identity = 44/167 (26.35%), Postives = 75/167 (44.91%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYET-SRKLANYKAYTLPVLKYFE 790
            K+I ++  PG     G     +    GY ++  GD LR  V   S++G    K   ++M  G+LVP D  L +L D  +  + +    +I+GYPR   Q ++ +  IG   +L    +D+        LL   +   +    D  ET  ++L  Y   T PV+ +++
Sbjct:   25 KIIFVVGGPGSGK--GTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERG----KKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPTLL--LYVDAGAETMTQRLLKRGETSGRVD--DNEETIKKRLETYYNATEPVISFYD 181
[Close]
BLAST of Adenylate kinase vs. UniProt/SwissProt
Match: sp|Q920P5|KAD5_MOUSE (Adenylate kinase isoenzyme 5 OS=Mus musculus OX=10090 GN=Ak5 PE=1 SV=2)

HSP 1 Score: 78.9518 bits (193), Expect = 2.841e-15
Identity = 68/293 (23.21%), Postives = 132/293 (45.05%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSE-LKDLNCIQG-------------------------LFQYQTLSDKN-SCKGDISNDF----------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDP----YETSRKLANYKAYTLPVLKYFED 793
            +YL   +I +LFE+L + L+ S+P D I++L+  L+ VK   G ++ K+D F S   + L  LN  Q                          + Q+   SD + S   ++  ++          K+IL+I  PG      ++         Y+++G+ LRK++   S     +W +   ++ NG+L P++  +  +  ++  + ++E I+I+G+PR+  Q    ++ I    ++ VF+       C    L     +  + +  P      T R+L N+K    P++KYF++
Sbjct:    8 EYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSN--RKWSLIAKIITNGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLV-VFLA------CANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQE 291

HSP 2 Score: 57.7658 bits (138), Expect = 3.203e-8
Identity = 45/171 (26.32%), Postives = 78/171 (45.61%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKL 805
            K+I L+  PG     G     L    G+ ++  G+ LR+ +  ES+    R K+ + +M  GDLVP  + L +L +  +  L N +  +I+GYPR   Q ++    IG     H+ +      D  T  L      ++  E      +++L  Y   ++PV+ Y+E   +L
Sbjct:  377 KIIFLMGGPGSGK--GTQCEKLAEKYGFTHLSTGELLRQELTSESE----RSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGDP---HLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQL 538
[Close]
BLAST of Adenylate kinase vs. UniProt/SwissProt
Match: sp|Q9Y6K8|KAD5_HUMAN (Adenylate kinase isoenzyme 5 OS=Homo sapiens OX=9606 GN=AK5 PE=1 SV=2)

HSP 1 Score: 77.0258 bits (188), Expect = 1.158e-14
Identity = 66/293 (22.53%), Postives = 130/293 (44.37%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSE-LKDLNCIQG-------------------------LFQYQTLSDKN-SCKGDISNDF----------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDP----YETSRKLANYKAYTLPVLKYFED 793
            +YL    I +LFE+L + L+ S+P D +++L+  L+ VK   G ++ K+D F S   + L  LN  Q                          + Q+   SD + S   ++  ++          K+IL+I  PG      ++         Y+++G+ LRK++   S     +W +   ++  G+L P++  +  +  ++  + ++E I+I+G+PR+  Q    ++ I    ++ VF+       C    L     +  + +  P      T R+L N+K    P++KYF++
Sbjct:    8 EYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLV-VFLA------CANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQE 291

HSP 2 Score: 55.4546 bits (132), Expect = 1.975e-7
Identity = 46/175 (26.29%), Postives = 79/175 (45.14%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLAN----YKAYTLPVLKYFEDNQKL 805
            K+I +I  PG     G     L    G+ ++  G+ LR+ +  ES+    R K+ + +M  GDLVP  I L +L +  +  L +    +I+GYPR   Q ++    IG +  L + M      DC    +     +   S     +T++ +A     Y   ++PV+ Y+E   +L
Sbjct:  377 KIIFIIGGPGSGK--GTQCEKLVEKYGFTHLSTGELLREELASESE----RSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIG-DPQLVICM------DCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQL 538
[Close]
BLAST of Adenylate kinase vs. UniProt/SwissProt
Match: sp|A4IFD0|KAD5_BOVIN (Adenylate kinase isoenzyme 5 OS=Bos taurus OX=9913 GN=Ak5 PE=2 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 9.484e-14
Identity = 65/293 (22.18%), Postives = 129/293 (44.03%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSE-LKDLNCIQG-------------------------LFQYQTLSDKN-SCKGDISNDF----------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDP----YETSRKLANYKAYTLPVLKYFED 793
            +YL    I +LFE+L + L+ S+P D +++L+  L+ VK   G ++ K+D F S   + L  LN  Q                          + Q+   SD + S   ++  ++          K+IL+I  PG      ++         Y+++G+ LRK++   S     +W +   ++  G+L P++  +  +  ++  + ++  I+I+G+PR+  Q    ++ I    ++ VF+       C    L     +  + +  P      T R+L N+K    P++KYF++
Sbjct:    8 EYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQMPDEVGIVIDGFPRDVAQALSFEDQICTPDLV-VFLA------CTNQRLKERLLKRAEQQGRPDDNLKATQRRLMNFKQNAAPLVKYFQE 291

HSP 2 Score: 53.1434 bits (126), Expect = 9.464e-7
Identity = 46/170 (27.06%), Postives = 76/170 (44.71%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDE-IKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYET-SRKLANYKAYTLPVLKYFEDNQKL 805
            K+I +I  PG     G     L    G+ ++  S  + +Q E      R K+ + +M  G+LVP  I L +L +  +  L N +  +I+GYPR   Q ++    IG   +  V  +D   +     LL     RN     D   T +++L  Y   ++PV+ Y+E   +L
Sbjct:  377 KIIFMIGGPGSGK--GTQCGKLAEKYGFTHL--STDELLQNELSSESGRSKLIRDIMERGELVPSGIILELLKEAMVASLSNTKGFLIDGYPREVKQGEEFGRRIGDPHL--VICMDCSADTMTNRLLQ--RSRNSPQADDNTTTIAKRLETYYRASIPVVAYYETKTQL 538
[Close]
BLAST of Adenylate kinase vs. UniProt/SwissProt
Match: sp|Q3SSU5|KAD_NITWN (Adenylate kinase OS=Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255) OX=323098 GN=adk PE=3 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 7.838e-10
Identity = 44/181 (24.31%), Postives = 85/181 (46.96%), Query Frame = 2 
Query:  308 ILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLD----------NAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII 814
            ++L+  PG     G     L ++ G + +  GD LR  V   +  G+     +K +M +G LVP+D+ + ++ D ++    K+  I++G+PR   Q + LD          +A+   R+    ++   EN            R  D   +P   S++LA+Y+A T P+++Y+ +  +L  +
Sbjct:    3 LILLGPPGAGK--GTQAQRLVHHYGIIQLSTGDMLRAAVAAGTPVGLK----AKDIMASGGLVPDDVVIGIISDRLEQADAKDGFILDGFPRTVPQAEALDILLQSKNLALDAVIELRVDESALLQRVENRVAETTARGEQVRADD---NPEVLSQRLASYRALTEPLIRYYSERGRLLTV 174
[Close]
BLAST of Adenylate kinase vs. UniProt/SwissProt
Match: sp|Q5VRN0|KCY1_ORYSJ (UMP-CMP kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=Os06g0109600 PE=2 SV=1)

HSP 1 Score: 61.2326 bits (147), Expect = 9.612e-10
Identity = 46/170 (27.06%), Postives = 87/170 (51.18%), Query Frame = 2 
Query:  305 VILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYET-SRKLANYKAYTLPVLKYFEDNQKL 805
            ++ +I  PG     G   + +    G+ ++  GD LR+  + ++++G     + K+LMN G LV  D+ + +L   ++   N +  +++G+PRNE      +N I +E    +F ID  + +    +LN    RN+  + D  +T  R+   ++  TLPV++Y+E   KL
Sbjct:   21 IVFVIGGPGSGK--GTQCAKIVKQFGFTHLSAGDLLREEAKYDTEQGT----MIKNLMNEGKLVSSDLIVKLLFKAMRESGNDKF-LVDGFPRNEENRHAYENIIHIEPEFLLF-IDCSKEEMERRILN----RNQGRDDDNIDTIRRRFDVFQQQTLPVIQYYEKRGKL 178
[Close]
BLAST of Adenylate kinase vs. TrEMBL
Match: A0A4E0RMN6 (Adenylate kinase isoenzyme 5 OS=Fasciola hepatica OX=6192 GN=D915_007311 PE=4 SV=1)

HSP 1 Score: 125.946 bits (315), Expect = 7.352e-29
Identity = 79/267 (29.59%), Postives = 137/267 (51.31%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNF----HSMNSELKDLNCIQGLFQYQTLSDKNSCKGDISNDFKVILLISAPG-EPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEF----DPYETSRKLANYKAYTLPVLKYFEDNQKLTII 814
            +YL  N + +LFE L   L+  +PAD + +LQ+ LE +K +G+   ++D F    HS    +      + L +Y  L   ++ +  I  +  +I +++ PG    +    L N Y    +++MGD LR R + E+Q+  SRW  S   +N G+L+P ++ +  L+  +    +    II+G+PR + Q +DL + IGL+ +  VF+ID+ E  C+  L      R +  EF     P     ++  +K  TLPV K  +++ KL +I
Sbjct:   15 EYLTKNGVPQLFECLMTGLMYHRPADHLNYLQECLEKIKKQGISGVRWDLFLERQHSSPKPISPHKGGENLSKYDPLPGIDTLRVKIRPNTSIICVLAGPGVNKSRYSQGLINHYPTFVHLHMGDLLRNRAKLETQRKSSRWVDSHLKINAGELLPHEMVMESLIWNLNQHSDASGFIIDGFPRTDKQYEDLKSQIGLDSLACVFLIDAAEEFCKFQLKE----RGQQDEFWKDNTPDAIDNRICLFKLQTLPVCKCIDNDGKLRVI 277
[Close]
BLAST of Adenylate kinase vs. TrEMBL
Match: A0A5J4NBT0 (Adenylate kinase OS=Paragonimus westermani OX=34504 GN=DEA37_0002617 PE=4 SV=1)

HSP 1 Score: 123.635 bits (309), Expect = 4.020e-28
Identity = 85/284 (29.93%), Postives = 138/284 (48.59%), Query Frame = 2 
Query:    8 LDIKLVNMIEN---DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNF---------HSMNSELKDLNCIQGLFQYQTLSDKNSCKGDISNDFKVILLISAPG-EPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTAL--LNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII 814
            +D+K V M      DYL  N I +LFE L   L+  +PAD + +LQ+ LE +K +GL   ++D F            ++E  DL       +Y  L   +  K  I +D  VI ++  PG         L + Y N  ++ MGD LR R + E+Q+  S+W      +N G+L+P +I +  L+  +         II+G+PR + Q +++ N +GLE +  VF+ID+ E+ CR  L      D   KD      +   ++  +K  TLP+ K  + + KL ++
Sbjct:    6 MDVKKVTMTPTETKDYLAKNKIPQLFECLMTGLMYHRPADYVNYLQECLEKIKRQGLSGVRWDLFLETRPTSSPTVASNEAADLTS-----KYDPLPGVDFSKARIRSDASVICVLGGPGINRTSYSQGLISHYPNFVHLCMGDLLRNRTKMEAQREGSKWANLVEQINAGELLPHEIVVESLISSLNQHSQASGFIIDGFPRTQQQYEEMKNQVGLENLACVFLIDTAEDFCRKQLKERGTSDDLWKDQVLKAIDN--RICLFKLQTLPMCKCIDADGKLRVV 282
[Close]
BLAST of Adenylate kinase vs. TrEMBL
Match: A0A5K3FRF7 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 4.134e-28
Identity = 81/271 (29.89%), Postives = 128/271 (47.23%), Query Frame = 2 
Query:   38 NDYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNFHSMNSELKDLNCI----------QGLFQYQTLSDKNSCKGDISNDFKVILLISAPG-EPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDC-RTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII 814
            N+YL S+ I +LFE L   L+  +PAD +Q++Q+ LE +K  G    ++D F      ++D  C+          +   +YQ L   +  +  I     +I ++S PG +       +   Y N  ++ MGD  +   + E +K  SRWK +   +N+GD  PED+ L +L+  +         II+GYPR   Q  DL   IG +R+  V +ID+ E  C R   +     R  D         RK+  YK  TL + K  +D +KL I+
Sbjct:   14 NEYLASHEIPQLFECLITGLMFHRPADPVQYIQECLEQIKRIGFRSVRWDLF------VEDKRCVLPPLGLKRNTEPFSKYQPLVGTDCLRLRIRPQTSIICVLSPPGIDGFGFSERMMRRYPNFVHICMGDLAKNCAKIEERKPNSRWKDAIEYINSGDFAPEDMVLELLIWNLNQYPTSTGFIIDGYPRTFKQYDDLKIHIGGDRLSGVVLIDAPEEKCLRRIHIANQRKRQCDEHLSFDVVQRKMCMYKKVTLAMCKVIDDEKKLYIV 278
[Close]
BLAST of Adenylate kinase vs. TrEMBL
Match: A0A5K3FQT2 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 1.205e-27
Identity = 81/271 (29.89%), Postives = 128/271 (47.23%), Query Frame = 2 
Query:   38 NDYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNFHSMNSELKDLNCI----------QGLFQYQTLSDKNSCKGDISNDFKVILLISAPG-EPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDC-RTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII 814
            N+YL S+ I +LFE L   L+  +PAD +Q++Q+ LE +K  G    ++D F      ++D  C+          +   +YQ L   +  +  I     +I ++S PG +       +   Y N  ++ MGD  +   + E +K  SRWK +   +N+GD  PED+ L +L+  +         II+GYPR   Q  DL   IG +R+  V +ID+ E  C R   +     R  D         RK+  YK  TL + K  +D +KL I+
Sbjct:   14 NEYLASHEIPQLFECLITGLMFHRPADPVQYIQECLEQIKRIGFRSVRWDLF------VEDKRCVLPPLGLKRNTEPFSKYQPLVGTDCLRLRIRPQTSIICVLSPPGIDGFGFSERMMRRYPNFVHICMGDLAKNCAKIEERKPNSRWKDAIEYINSGDFAPEDMVLELLIWNLNQYPTSTGFIIDGYPRTFKQYDDLKIHIGGDRLSGVVLIDAPEEKCLRRIHIANQRKRQCDEHLSFDVVQRKMCMYKKVTLAMCKVIDDEKKLYIV 278
[Close]
BLAST of Adenylate kinase vs. TrEMBL
Match: A0A5K3FQ64 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 1.211e-27
Identity = 81/271 (29.89%), Postives = 128/271 (47.23%), Query Frame = 2 
Query:   38 NDYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNFHSMNSELKDLNCI----------QGLFQYQTLSDKNSCKGDISNDFKVILLISAPG-EPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDC-RTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII 814
            N+YL S+ I +LFE L   L+  +PAD +Q++Q+ LE +K  G    ++D F      ++D  C+          +   +YQ L   +  +  I     +I ++S PG +       +   Y N  ++ MGD  +   + E +K  SRWK +   +N+GD  PED+ L +L+  +         II+GYPR   Q  DL   IG +R+  V +ID+ E  C R   +     R  D         RK+  YK  TL + K  +D +KL I+
Sbjct:   14 NEYLASHEIPQLFECLITGLMFHRPADPVQYIQECLEQIKRIGFRSVRWDLF------VEDKRCVLPPLGLKRNTEPFSKYQPLVGTDCLRLRIRPQTSIICVLSPPGIDGFGFSERMMRRYPNFVHICMGDLAKNCAKIEERKPNSRWKDAIEYINSGDFAPEDMVLELLIWNLNQYPTSTGFIIDGYPRTFKQYDDLKIHIGGDRLSGVVLIDAPEEKCLRRIHIANQRKRQCDEHLSFDVVQRKMCMYKKVTLAMCKVIDDEKKLYIV 278
[Close]
BLAST of Adenylate kinase vs. Ensembl Cavefish
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:103029093])

HSP 1 Score: 75.485 bits (184), Expect = 3.948e-15
Identity = 69/291 (23.71%), Postives = 129/291 (44.33%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSELKDLNCIQG----------------------------LFQYQTLSDKN-SCKGDISNDF----------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFED 793
            +YL    I +LFE+L   L+  +P D I +L+  L+ V+   G E+ ++D F  +  E K L  + G                            + Q+   SD + S   ++  ++          KVIL+I  PG      ++         YV++G+ LRKR+   +     +W +   ++ NG+L P++  +  +  +I  + +   I+I+G+PR+  Q    ++ I    ++ VF+  S  N      L     +    + +P  T R+LAN+K   +P++KYF++
Sbjct:    8 EYLSRREIPQLFESLLTGLMYYRPDDPIDYLECCLKKVRELGGTEKVRWDTF--VGQEKKSLPPLNGGQSRRSFFRNGMSNSPNFPYRRYDRLPPIHQFSIESDSDLSETAELIEEYEVFDPSRPRPKVILIIGGPGSGKGTQSLKIAERYGFEYVSVGELLRKRMIHNATSN-RKWSLIAKIITNGELAPQETTITEIKQKIMKIPDANGIVIDGFPRDVGQALSFEDQICTPDLV-VFLACS--NQRLKERLEKRAEQQGRPDDNPKATERRLANFKQNAVPLVKYFQE 292
[Close]
BLAST of Adenylate kinase vs. Ensembl Cavefish
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:103029093])

HSP 1 Score: 75.485 bits (184), Expect = 4.425e-15
Identity = 69/293 (23.55%), Postives = 129/293 (44.03%), Query Frame = 2 
Query:   38 NDYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSELKDLNCIQG----------------------------LFQYQTLSDKN-SCKGDISNDF----------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDN 796
             +YL    I +LFE+L   L+  +P D I +L+  L+ V+   G E+ ++D F  +  E K L  + G                            + Q+   SD + S   ++  ++          KVIL+I  PG      ++         YV++G+ LRKR+   +     +W +   ++ NG+L P++  +  +  +I  + +   I+I+G+PR+  Q    ++ I    ++ VF+  S  N      L     +    + +P  T R+LAN+K   +P++KYF++ 
Sbjct:    7 KEYLSRREIPQLFESLLTGLMYYRPDDPIDYLECCLKKVRELGGTEKVRWDTF--VGQEKKSLPPLNGGQSRRSFFRNVLPDSPNFPYRRYDRLPPIHQFSIESDSDLSETAELIEEYEVFDPSRPRPKVILIIGGPGSGKGTQSLKIAERYGFEYVSVGELLRKRMIHNATSN-RKWSLIAKIITNGELAPQETTITEIKQKIMKIPDANGIVIDGFPRDVGQALSFEDQICTPDLV-VFLACS--NQRLKERLEKRAEQQGRPDDNPKATERRLANFKQNAVPLVKYFQEK 293
[Close]
BLAST of Adenylate kinase vs. Ensembl Cavefish
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:103029093])

HSP 1 Score: 75.485 bits (184), Expect = 4.425e-15
Identity = 69/293 (23.55%), Postives = 129/293 (44.03%), Query Frame = 2 
Query:   38 NDYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSELKDLNCIQG----------------------------LFQYQTLSDKN-SCKGDISNDF----------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDN 796
             +YL    I +LFE+L   L+  +P D I +L+  L+ V+   G E+ ++D F  +  E K L  + G                            + Q+   SD + S   ++  ++          KVIL+I  PG      ++         YV++G+ LRKR+   +     +W +   ++ NG+L P++  +  +  +I  + +   I+I+G+PR+  Q    ++ I    ++ VF+  S  N      L     +    + +P  T R+LAN+K   +P++KYF++ 
Sbjct:    7 KEYLSRREIPQLFESLLTGLMYYRPDDPIDYLECCLKKVRELGGTEKVRWDTF--VGQEKKSLPPLNGGQSRRSFFRNVLPDSPNFPYRRYDRLPPIHQFSIESDSDLSETAELIEEYEVFDPSRPRPKVILIIGGPGSGKGTQSLKIAERYGFEYVSVGELLRKRMIHNATSN-RKWSLIAKIITNGELAPQETTITEIKQKIMKIPDANGIVIDGFPRDVGQALSFEDQICTPDLV-VFLACS--NQRLKERLEKRAEQQGRPDDNPKATERRLANFKQNAVPLVKYFQEK 293
[Close]
BLAST of Adenylate kinase vs. Ensembl Cavefish
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:103035193])

HSP 1 Score: 50.0618 bits (118), Expect = 3.294e-7
Identity = 46/171 (26.90%), Postives = 79/171 (46.20%), Query Frame = 2 
Query:  293 NDFKVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCN-KELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLAN--YKAYTLPVLKYFE 790
             D K+I ++  PG     G     +    GY ++  GD LR  V   S++G    K  +++M  G+LVP D  L ++ D +    +  +  +I+GYPR   Q ++ +  IG   +L    +D+        L+   +   +    D  ET +K  +  YKA T PV+ ++E
Sbjct:    6 KDAKIIFVVGGPGSGK--GTQCEKVVAKYGYTHLSSGDLLRAEVASGSERG----KQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEEFEKKIGAPALL--LYVDAKSETMVKRLMKRGETSGRAD--DNEETIKKRLDLYYKA-TEPVITFYE 165
[Close]
BLAST of Adenylate kinase vs. Ensembl Cavefish
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:103035193])

HSP 1 Score: 50.447 bits (119), Expect = 3.773e-7
Identity = 50/194 (25.77%), Postives = 86/194 (44.33%), Query Frame = 2 
Query:  224 NCIQGLFQYQTLSDKNSCKGDISNDFKVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCN-KELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLAN--YKAYTLPVLKYFE 790
             C   L++  T       + D   D K+I ++  PG     G     +    GY ++  GD LR  V   S++G    K  +++M  G+LVP D  L ++ D +    +  +  +I+GYPR   Q ++ +  IG   +L    +D+        L+   +   +    D  ET +K  +  YKA T PV+ ++E
Sbjct:    4 GCFSALWRRST--HPADPQPDKIKDAKIIFVVGGPGSGK--GTQCEKVVAKYGYTHLSSGDLLRAEVASGSERG----KQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEEFEKKIGAPALL--LYVDAKSETMVKRLMKRGETSGRAD--DNEETIKKRLDLYYKA-TEPVITFYE 184
[Close]
BLAST of Adenylate kinase vs. Ensembl Sea Lamprey
Match: ak5l (adenylate kinase 5, like [Source:ZFIN;Acc:ZDB-GENE-050410-2])

HSP 1 Score: 48.1358 bits (113), Expect = 3.898e-7
Identity = 28/137 (20.44%), Postives = 68/137 (49.64%), Query Frame = 2 
Query:  386 VNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDN 796
            V++G+ LR+ V + +     +W++   +++ G+L P++ A+  L        +    +I+G+PR  +Q    +  +G      V ++       R  L    D R+   + +P    R+LA ++ +T+P+++++++ 
Sbjct:   23 VSLGEVLRQHVLQRAPSN-RKWRLIAQIISKGELAPQETAIWELKQHFLQNPDAPGFVIDGFPREISQALAFEEQVGAPDA--VILLACASERLRQRLGERAD-RHGRPDDNPRAVERRLATFRQHTVPLVQHYQER 155
[Close]
BLAST of Adenylate kinase vs. Ensembl Yeast
Match: URA6 (Uridylate kinase; catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP) [Source:SGD;Acc:S000001507])

HSP 1 Score: 49.2914 bits (116), Expect = 9.813e-8
Identity = 49/181 (27.07%), Postives = 84/181 (46.41%), Query Frame = 2 
Query:  305 VILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIK--LLCNKELIIIEGYPRNENQIKDLDNAIGLERML----HVFMIDSFENDCRTALLNCYDFRNKDSEF--DPYETSRKLAN-YKAYTLPVLKYFEDNQKLTII 814
            VI ++  PG     G     L  +  +V++  GD LR    ++ + G    ++ K+ +  G +VP++I L +L + I   +  NK   +I+G+PR       +D AI  ER +     +   D  E+     LL     R K S    D  E+ +K  N +K  ++PV++YFE   K+  +
Sbjct:   18 VIFVLGGPGAGK--GTQCEKLVKDYSFVHLSAGDLLR---AEQGRAGSQYGELIKNCIKEGQIVPQEITLALLRNAISDNVKANKHKFLIDGFPRK------MDQAISFERDIVESKFILFFDCPEDIMLERLLE----RGKTSGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRV 183
[Close]
BLAST of Adenylate kinase vs. Ensembl Nematostella
Match: EDO38863 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBK8])

HSP 1 Score: 45.0542 bits (105), Expect = 8.024e-6
Identity = 40/172 (23.26%), Postives = 79/172 (45.93%), Query Frame = 2 
Query:  308 ILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERML----HVFMIDSFENDCRTALLNCYDFRNKDSEFDPYET-SRKLANYKAYTLPVLKYFEDNQK 802
            I+ +  PG     G I  ++     Y ++  GD LR+ V + +++G    ++   +M  G LVP++I + +L D ++   +    +I+G+PR      D+D  I  E  +     V  ++  E   +  LL   +   +    D  ET  ++   +   T+PV++++E   K
Sbjct:    4 IITLGGPGAGK--GTICDSVVKKYNYCHLSAGDLLREEVTRGNERG----QMITEMMREGKLVPKEITIGLLQDAMREHKDMPGFLIDGFPR------DIDQGITFEEQVTDSDFVLYLECTEEVMQERLLKRAETSGRPD--DNIETIKKRFVTFLEKTVPVVEHYEKQSK 161
[Close]
BLAST of Adenylate kinase vs. Ensembl Medaka
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:101172192])

HSP 1 Score: 68.1662 bits (165), Expect = 1.295e-12
Identity = 67/292 (22.95%), Postives = 126/292 (43.15%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKS-KGLEEFKYDNFHSMNSELKDLNCIQG------LF----------------------QYQTLSDKN-SCKGDISNDF----------KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDN 796
            +YL    I +LFE+L   L+  +P D I  L+  L+  +   G E+ ++D F  +  E K L  + G      LF                      Q+   SD + S   ++  ++          KVIL+I  PG      ++         YV++G+ LRK++   +     +W +   ++ NG+L P++  +  +  +I  +     I+I+G+PR+  Q    ++ I    ++ VF+  +  N      L     +    + +P    R+L N+K  T+P++KYF++ 
Sbjct:    8 EYLARREIPQLFESLLTGLMYYRPDDPIDFLESCLKKARELGGPEKVRWDTF--VGQEKKSLPPLNGGQSRRSLFRNVLPESPNFPYRRYDRLPPISQFSIESDSDLSETAELIEEYEVFDPCRPRPKVILVIGGPGSGKGTQSLKIAERYGFQYVSVGELLRKKMIHNATSN-RKWSLIAKIITNGELAPQETTITEIKQKIMKIPEANGIVIDGFPRDVGQALSFEDQICTPDLV-VFL--ACANHRLKERLQKRAEQQGRPDDNPKAIDRRLTNFKQNTIPLVKYFQER 293
[Close]
BLAST of Adenylate kinase vs. Ensembl Medaka
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:101172192])

HSP 1 Score: 59.3066 bits (142), Expect = 1.243e-9
Identity = 40/165 (24.24%), Postives = 80/165 (48.48%), Query Frame = 2 
Query:  302 KVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDN 796
            KVIL+I  PG      ++         YV++G+ LRK++   +     +W +   ++ NG+L P++  +  +  +I  +     I+I+G+PR+  Q    ++ I    ++ VF+  +  N      L     +    + +P    R+L N+K  T+P++KYF++ 
Sbjct:  178 KVILVIGGPGSGKGTQSLKIAERYGFQYVSVGELLRKKMIHNATSN-RKWSLIAKIITNGELAPQETTITEIKQKIMKIPEANGIVIDGFPRDVGQALSFEDQICTPDLV-VFL--ACANHRLKERLQKRAEQQGRPDDNPKAIDRRLTNFKQNTIPLVKYFQER 338
[Close]
BLAST of Adenylate kinase vs. Ensembl Medaka
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:101156342])

HSP 1 Score: 48.521 bits (114), Expect = 1.365e-6
Identity = 49/173 (28.32%), Postives = 81/173 (46.82%), Query Frame = 2 
Query:  293 NDFKVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCN-KELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDF--RNKDSEFDPYETSRKLAN--YKAYTLPVLKYFE 790
             D K+I ++  PG     G     +    GY ++  GD LR  V   S +G    K  +++M  G+LVP D  L ++ D +    +  +  +I+GYPR   Q ++ +  IG   +L    +D+        LL   +   R+ D+E    ET +K  +  YKA T PV+ ++E
Sbjct:   12 KDAKIIFVVGGPGSGK--GTQCERIVAKYGYTHLSSGDLLRAEVASGSDRG----KQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEEFEKKIGKPCLL--LYVDAKSETMIKRLLKRGETSGRSDDNE----ETIKKRLDLYYKA-TEPVIAFYE 171
[Close]
BLAST of Adenylate kinase vs. Ensembl Medaka
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:101156342])

HSP 1 Score: 48.1358 bits (113), Expect = 1.625e-6
Identity = 49/173 (28.32%), Postives = 81/173 (46.82%), Query Frame = 2 
Query:  293 NDFKVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCN-KELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDF--RNKDSEFDPYETSRKLAN--YKAYTLPVLKYFE 790
             D K+I ++  PG     G     +    GY ++  GD LR  V   S +G    K  +++M  G+LVP D  L ++ D +    +  +  +I+GYPR   Q ++ +  IG   +L    +D+        LL   +   R+ D+E    ET +K  +  YKA T PV+ ++E
Sbjct:    6 KDAKIIFVVGGPGSGK--GTQCERIVAKYGYTHLSSGDLLRAEVASGSDRG----KQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEEFEKKIGKPCLL--LYVDAKSETMIKRLLKRGETSGRSDDNE----ETIKKRLDLYYKA-TEPVIAFYE 165
[Close]
BLAST of Adenylate kinase vs. Ensembl Medaka
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:101156342])

HSP 1 Score: 48.1358 bits (113), Expect = 1.639e-6
Identity = 49/173 (28.32%), Postives = 81/173 (46.82%), Query Frame = 2 
Query:  293 NDFKVILLISAPGEPHKIGNILSNLYNNIGYVNM--GDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCN-KELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDF--RNKDSEFDPYETSRKLAN--YKAYTLPVLKYFE 790
             D K+I ++  PG     G     +    GY ++  GD LR  V   S +G    K  +++M  G+LVP D  L ++ D +    +  +  +I+GYPR   Q ++ +  IG   +L    +D+        LL   +   R+ D+E    ET +K  +  YKA T PV+ ++E
Sbjct:    6 KDAKIIFVVGGPGSGK--GTQCERIVAKYGYTHLSSGDLLRAEVASGSDRG----KQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEEFEKKIGKPCLL--LYVDAKSETMIKRLLKRGETSGRSDDNE----ETIKKRLDLYYKA-TEPVIAFYE 165
[Close]
BLAST of Adenylate kinase vs. Planmine SMEST
Match: SMESG000053924.1 (SMESG000053924.1)

HSP 1 Score: 536.569 bits (1381), Expect = 0.000e+0
Identity = 262/262 (100.00%), Postives = 262/262 (100.00%), Query Frame = 2 
Query:   29 MIENDYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNFHSMNSELKDLNCIQGLFQYQTLSDKNSCKGDISNDFKVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII 814
            MIENDYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNFHSMNSELKDLNCIQGLFQYQTLSDKNSCKGDISNDFKVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII
Sbjct:    1 MIENDYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNFHSMNSELKDLNCIQGLFQYQTLSDKNSCKGDISNDFKVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII 262
[Close]
BLAST of Adenylate kinase vs. Planmine SMEST
Match: SMESG000024490.1 (SMESG000024490.1)

HSP 1 Score: 140.969 bits (354), Expect = 3.193e-38
Identity = 85/260 (32.69%), Postives = 134/260 (51.54%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNFHSMNS-ELKDLN-CIQGLFQYQTLSDKNSCKGDISNDFKVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII 814
            DYL  N I +LFE L   L+  +P   I +LQ  L+ +K +G+   ++D F    S  L  ++   +  F  + ++D N+ + +IS D  +++ I+ P                  ++               KGIS+WKV+ SLM+ G+L P D+ L  L+ E+    +    IIEGYPRN  Q++D +  IG+ R+  V ++D  E+ C+ AL+         ++  P    R++ANYKAYTLPV KYF+D QKL +I
Sbjct:   16 DYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPISPSCKEEFTAEGVTDSNTIQLNISYDVALVIFIAGP-----------------DFIT--------------KGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFIGMNRLSFVILVDCEEDTCQQALVQRPPIEGW-TDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMI 243
[Close]
BLAST of Adenylate kinase vs. Planmine SMEST
Match: SMESG000024490.1 (SMESG000024490.1)

HSP 1 Score: 109.383 bits (272), Expect = 7.022e-27
Identity = 75/260 (28.85%), Postives = 125/260 (48.08%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNFHSMNS-ELKDLN-CIQGLFQYQTLSDKNSCKGDISNDFKVILLISAPGEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERMLHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVLKYFEDNQKLTII 814
            DYL  N I +LFE L   L+  +P   I +LQ  L+ +K +G+   ++D F    S  L  ++   +  F  + ++D N+ + +IS D  +++ I+ P                  ++               KGIS+WKV+ SLM+ G+L P D+ L  L+ E+             Y  + + +++    I + R+  V ++D  E+ C+ AL+         ++  P    R++ANYKAYTLPV KYF+D QKL +I
Sbjct:   16 DYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPISPSCKEEFTAEGVTDSNTIQLNISYDVALVIFIAGP-----------------DFIT--------------KGISKWKVAASLMHCGELAPNDMVLETLIKEL------------NYHTDVSGLRE----ICMNRLSFVILVDCEEDTCQQALVQRPPIEGW-TDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMI 227
[Close]
BLAST of Adenylate kinase vs. Planmine SMEST
Match: SMESG000020486.1 (SMESG000020486.1)

HSP 1 Score: 67.0106 bits (162), Expect = 2.407e-13
Identity = 43/156 (27.56%), Postives = 79/156 (50.64%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNFHSMNSELKDLNCIQGL----FQYQTLSDKNSCKGDISNDFKVILLISAPGE-PHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVP 493
            DYL  N I +LFE L   L+  +P D I +LQ+ LE +K +G+    +D F  + S+   L  I       F+ + L +  +    I  +  ++++   PG    +I + LS+ +     +++G ++R+R   E++   S+W     L+++GDL P
Sbjct:   16 DYLSKNEIPQLFECLMTGLMYHRPTDYINYLQECLEKIKKQGVNAVHWDMF--LESKKTPLPPIAPTPKENFRPEPLPEIGTLHLKIDLNSSIVIIQGGPGTGKSQICHRLSSEFPEYAAIDLGLNIRERANLEAKDLKSKWNHVAELIHDGDLAP 169
[Close]
BLAST of Adenylate kinase vs. Planmine SMEST
Match: SMESG000020486.1 (SMESG000020486.1)

HSP 1 Score: 67.3958 bits (163), Expect = 3.817e-13
Identity = 43/156 (27.56%), Postives = 79/156 (50.64%), Query Frame = 2 
Query:   41 DYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEFKYDNFHSMNSELKDLNCIQGL----FQYQTLSDKNSCKGDISNDFKVILLISAPGE-PHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNNGDLVP 493
            DYL  N I +LFE L   L+  +P D I +LQ+ LE +K +G+    +D F  + S+   L  I       F+ + L +  +    I  +  ++++   PG    +I + LS+ +     +++G ++R+R   E++   S+W     L+++GDL P
Sbjct:   16 DYLSKNEIPQLFECLMTGLMYHRPTDYINYLQECLEKIKKQGVNAVHWDMF--LESKKTPLPPIAPTPKENFRPEPLPEIGTLHLKIDLNSSIVIIQGGPGTGKSQICHRLSSEFPEYAAIDLGLNIRERANLEAKDLKSKWNHVAELIHDGDLAP 169
The following BLAST results are available for this feature:
BLAST of Adenylate kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AK52.411e-1522.53adenylate kinase 5 [Source:HGNC Symbol;Acc:HGNC:36... [more]
AK52.749e-1021.17adenylate kinase 5 [Source:HGNC Symbol;Acc:HGNC:36... [more]
AK17.411e-726.95adenylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:36... [more]
AK17.411e-726.95adenylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:36... [more]
AK11.123e-626.95adenylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:36... [more]
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BLAST of Adenylate kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
F13E6.29.396e-1732.96pep chromosome:WBcel235:X:10668280:10674293:-1 gen... [more]
F40F8.11.361e-924.59UMP-CMP kinase 2 [Source:UniProtKB/Swiss-Prot;Acc... [more]
F40F8.11.362e-924.85UMP-CMP kinase 2 [Source:UniProtKB/Swiss-Prot;Acc... [more]
F40F8.11.362e-924.85UMP-CMP kinase 2 [Source:UniProtKB/Swiss-Prot;Acc... [more]
F40F8.11.362e-924.85UMP-CMP kinase 2 [Source:UniProtKB/Swiss-Prot;Acc... [more]
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BLAST of Adenylate kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG95413.246e-624.71gene:FBgn0032083 transcript:FBtr0332206[more]
CG95413.636e-624.71gene:FBgn0032083 transcript:FBtr0332207[more]
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BLAST of Adenylate kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ak54.486e-1221.65adenylate kinase 5 [Source:ZFIN;Acc:ZDB-GENE-03013... [more]
ak13.850e-626.79adenylate kinase 1 [Source:ZFIN;Acc:ZDB-GENE-04082... [more]
ak14.480e-626.79adenylate kinase 1 [Source:ZFIN;Acc:ZDB-GENE-04082... [more]
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BLAST of Adenylate kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ak54.040e-1221.16adenylate kinase 5 [Source:NCBI gene;Acc:100127649... [more]
ak15.497e-1121.95adenylate kinase 1 [Source:NCBI gene;Acc:448536][more]
ak57.322e-821.43adenylate kinase 5 [Source:NCBI gene;Acc:100127649... [more]
ak12.046e-625.90adenylate kinase 1 [Source:NCBI gene;Acc:448536][more]
ak12.266e-627.38adenylate kinase 1 [Source:NCBI gene;Acc:448536][more]
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BLAST of Adenylate kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ak54.062e-1623.21adenylate kinase 5 [Source:MGI Symbol;Acc:MGI:2677... [more]
Ak54.348e-1026.32adenylate kinase 5 [Source:MGI Symbol;Acc:MGI:2677... [more]
Ak11.070e-626.35adenylate kinase 1 [Source:MGI Symbol;Acc:MGI:8797... [more]
Ak11.070e-626.35adenylate kinase 1 [Source:MGI Symbol;Acc:MGI:8797... [more]
Ak11.551e-626.35adenylate kinase 1 [Source:MGI Symbol;Acc:MGI:8797... [more]
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BLAST of Adenylate kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q920P5|KAD5_MOUSE2.841e-1523.21Adenylate kinase isoenzyme 5 OS=Mus musculus OX=10... [more]
sp|Q9Y6K8|KAD5_HUMAN1.158e-1422.53Adenylate kinase isoenzyme 5 OS=Homo sapiens OX=96... [more]
sp|A4IFD0|KAD5_BOVIN9.484e-1422.18Adenylate kinase isoenzyme 5 OS=Bos taurus OX=9913... [more]
sp|Q3SSU5|KAD_NITWN7.838e-1024.31Adenylate kinase OS=Nitrobacter winogradskyi (stra... [more]
sp|Q5VRN0|KCY1_ORYSJ9.612e-1027.06UMP-CMP kinase 1 OS=Oryza sativa subsp. japonica O... [more]
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BLAST of Adenylate kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0RMN67.352e-2929.59Adenylate kinase isoenzyme 5 OS=Fasciola hepatica ... [more]
A0A5J4NBT04.020e-2829.93Adenylate kinase OS=Paragonimus westermani OX=3450... [more]
A0A5K3FRF74.134e-2829.89Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A5K3FQT21.205e-2729.89Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A5K3FQ641.211e-2729.89Uncharacterized protein OS=Mesocestoides corti OX=... [more]
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BLAST of Adenylate kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ak53.948e-1523.71adenylate kinase 5 [Source:NCBI gene;Acc:103029093... [more]
ak54.425e-1523.55adenylate kinase 5 [Source:NCBI gene;Acc:103029093... [more]
ak54.425e-1523.55adenylate kinase 5 [Source:NCBI gene;Acc:103029093... [more]
ak13.294e-726.90adenylate kinase 1 [Source:NCBI gene;Acc:103035193... [more]
ak13.773e-725.77adenylate kinase 1 [Source:NCBI gene;Acc:103035193... [more]
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BLAST of Adenylate kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ak5l3.898e-720.44adenylate kinase 5, like [Source:ZFIN;Acc:ZDB-GENE... [more]
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BLAST of Adenylate kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
URA69.813e-827.07Uridylate kinase; catalyzes the seventh enzymatic ... [more]
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BLAST of Adenylate kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO388638.024e-623.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Adenylate kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ak51.295e-1222.95adenylate kinase 5 [Source:NCBI gene;Acc:101172192... [more]
ak51.243e-924.24adenylate kinase 5 [Source:NCBI gene;Acc:101172192... [more]
ak11.365e-628.32adenylate kinase 1 [Source:NCBI gene;Acc:101156342... [more]
ak11.625e-628.32adenylate kinase 1 [Source:NCBI gene;Acc:101156342... [more]
ak11.639e-628.32adenylate kinase 1 [Source:NCBI gene;Acc:101156342... [more]
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BLAST of Adenylate kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053924.10.000e+0100.00SMESG000053924.1[more]
SMESG000024490.13.193e-3832.69SMESG000024490.1[more]
SMESG000024490.17.022e-2728.85SMESG000024490.1[more]
SMESG000020486.12.407e-1327.56SMESG000020486.1[more]
SMESG000020486.13.817e-1327.56SMESG000020486.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007623 ID=SMED30007623|Name=Adenylate kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=815bp
ATTATAACTCGATATTAAGTTAGTAAATATGATTGAGAATGATTATTTAA
AATCAAATAACATTCAAGAATTATTTGAAGCTCTTACAGACAGCCTTTTG
CTGAGCCAACCGGCTGATATCATTCAGCATTTGCAAGACTCACTGGAAAA
TGTCAAATCCAAAGGCTTAGAAGAATTCAAGTACGATAATTTCCATTCAA
TGAATTCTGAGCTTAAAGATCTGAACTGTATTCAAGGATTGTTTCAATAT
CAAACTCTTTCAGATAAAAACAGCTGCAAAGGAGACATTTCAAATGATTT
CAAGGTTATTCTTTTGATATCAGCACCGGGGGAGCCACATAAGATTGGAA
ATATTTTATCGAATCTGTATAACAATATTGGTTATGTTAATATGGGAGAT
AGTCTTCGGAAACGAGTTCAAAAGGAATCACAAAAAGGAATAAGTAGATG
GAAAGTCAGTAAATCCTTAATGAATAACGGGGATCTAGTTCCGGAGGATA
TTGCATTGCATGTTTTACTGGATGAAATCAAGCTTCTTTGCAATAAAGAA
TTAATCATCATAGAAGGTTATCCGAGAAATGAAAATCAAATTAAGGATCT
CGATAATGCAATTGGATTGGAACGTATGTTACATGTGTTCATGATCGACA
GTTTTGAAAATGACTGTAGAACTGCGCTTTTGAACTGCTACGATTTCCGT
AACAAAGATTCAGAGTTTGATCCGTATGAGACCTCAAGAAAATTGGCTAA
TTACAAAGCTTATACTCTACCAGTTTTGAAATATTTTGAAGACAATCAAA
AATTAACAATAATAG
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protein sequence of SMED30007623-orf-1

>SMED30007623-orf-1 ID=SMED30007623-orf-1|Name=SMED30007623-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=262bp
MIENDYLKSNNIQELFEALTDSLLLSQPADIIQHLQDSLENVKSKGLEEF
KYDNFHSMNSELKDLNCIQGLFQYQTLSDKNSCKGDISNDFKVILLISAP
GEPHKIGNILSNLYNNIGYVNMGDSLRKRVQKESQKGISRWKVSKSLMNN
GDLVPEDIALHVLLDEIKLLCNKELIIIEGYPRNENQIKDLDNAIGLERM
LHVFMIDSFENDCRTALLNCYDFRNKDSEFDPYETSRKLANYKAYTLPVL
KYFEDNQKLTII
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0004017adenylate kinase activity
GO:0016740transferase activity
GO:0019205nucleobase-containing compound kinase activity
GO:0005524ATP binding
GO:0016301kinase activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
Vocabulary: biological process
TermDefinition
GO:0009165nucleotide biosynthetic process
GO:0044209AMP salvage
GO:0046940nucleoside monophosphate phosphorylation
GO:0006139nucleobase-containing compound metabolic process
GO:0016310phosphorylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000419prepharyngeal region
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR000850Adenylat/UMP-CMP_kin
IPR027417P-loop_NTPase
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000850Adenylate kinase/UMP-CMP kinasePRINTSPR00094ADENYLTKNASEcoord: 123..137
score: 37.51
coord: 244..258
score: 23.84
coord: 176..192
score: 35.59
IPR000850Adenylate kinase/UMP-CMP kinasePANTHERPTHR23359NUCLEOTIDE KINASEcoord: 117..259
NoneNo IPR availablePFAMPF00406ADKcoord: 118..257
e-value: 7.9E-14
score: 52.0
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 86..261
e-value: 6.9E-21
score: 76.7
NoneNo IPR availablePANTHERPTHR23359:SF107UMP-CMP KINASEcoord: 117..259
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 107..206