TBCC domain-containing protein 1

Overview
NameTBCC domain-containing protein 1
Smed IDSMED30007577
Length (bp)2321
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of TBCC domain-containing protein 1 (SMED30007577) t-SNE clustered cells

Violin plots show distribution of expression levels for TBCC domain-containing protein 1 (SMED30007577) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TBCC domain-containing protein 1 (SMED30007577) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TBCC domain-containing protein 1 (SMED30007577) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30007577

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30007577h1SMcG0014031 SmedASXL_012800SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
head regionSMED30007577h1SMcG0014031 OX_Smed_1.0.07058ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30007577h1SMcG0014031 dd_Smed_v4_12514_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of TBCC domain-containing protein 1 vs. Ensembl Human
Match: TBCCD1 (TBCC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25546])

HSP 1 Score: 330.487 bits (846), Expect = 1.684e-103
Identity = 198/587 (33.73%), Postives = 313/587 (53.32%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTK---KSIDM-EVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDP 1885
            LWV++EPF  G L V P P   S+H ++K+ +Y +++   G YP+L +  W+HIAC KLQL + L W  F     +S     +       L  C + EE E+ +N  S++  +F+L+LYIQQ+NK+SLR S +    EWP  +   +S D+ E     NKN ++  H  FV  ++ D++++L +P        +     +   A+ AL+ +I+G   +   I PL E+         +GFSK +KT S   L +W+RS L  NPF   ACL +GK+L W          + G+  + K    A   ++ P+     ++L+++S +  QT+A+SS TL  A +K+HRC+ S+ Y LSPLRSV+I+KCR S  +LGPV  T+ L +C++  ++A   RL +     C  + +T T PL+                             + N+ + FAP+ + YP LE+H+++  +    N+W+ PMV  VC   +  ++++LLPP +FY   IPF+ EG TT  P   PS Y++AL QR  + +  +  +K + LT +Q K F+ LVE +F  WL  +   +QL  L P
Sbjct:    8 LWVKAEPFIVGALQVPP-PSKFSLHYLRKISTYVQIRATEGAYPRLYWSTWRHIACGKLQLAKDLAWLYFEIFDSLSMKTPEERLEWSEVLSNCMSEEEVEKQRNQLSVDTLQFLLFLYIQQLNKVSLRTSLI--GEEWPSPRNKSQSPDLTEKSNCHNKNWNDYSHQAFVYDHLSDLLELLLDPKQLTASFHSTHSSLVSREAVVALSFLIEGTISRARKIYPLHELALWQPLHADSGFSKISKTFSFYKLETWLRSCLTGNPFGTSACLKSGKKLAWA-------HQVEGTTKRAKI---ACNTHVAPRM----HRLVVMSQVYKQTLAKSSDTLAGAHVKIHRCNESFIYLLSPLRSVTIEKCRNSIFVLGPVGTTLHLHSCDNVKVIAVCHRLSISSTTGCIFHVLTPTRPLIL----------------------------SGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMV--VCRENSDTRVFQLLPPCEFYVFIIPFEMEGDTTEIPGGLPSVYQKALGQREQKIQIWQKTVKEAHLTKDQRKQFQVLVENKFYEWLINTGHRQQLDSLVP 547          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Human
Match: TBCCD1 (TBCC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25546])

HSP 1 Score: 330.487 bits (846), Expect = 1.684e-103
Identity = 198/587 (33.73%), Postives = 313/587 (53.32%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTK---KSIDM-EVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDP 1885
            LWV++EPF  G L V P P   S+H ++K+ +Y +++   G YP+L +  W+HIAC KLQL + L W  F     +S     +       L  C + EE E+ +N  S++  +F+L+LYIQQ+NK+SLR S +    EWP  +   +S D+ E     NKN ++  H  FV  ++ D++++L +P        +     +   A+ AL+ +I+G   +   I PL E+         +GFSK +KT S   L +W+RS L  NPF   ACL +GK+L W          + G+  + K    A   ++ P+     ++L+++S +  QT+A+SS TL  A +K+HRC+ S+ Y LSPLRSV+I+KCR S  +LGPV  T+ L +C++  ++A   RL +     C  + +T T PL+                             + N+ + FAP+ + YP LE+H+++  +    N+W+ PMV  VC   +  ++++LLPP +FY   IPF+ EG TT  P   PS Y++AL QR  + +  +  +K + LT +Q K F+ LVE +F  WL  +   +QL  L P
Sbjct:    8 LWVKAEPFIVGALQVPP-PSKFSLHYLRKISTYVQIRATEGAYPRLYWSTWRHIACGKLQLAKDLAWLYFEIFDSLSMKTPEERLEWSEVLSNCMSEEEVEKQRNQLSVDTLQFLLFLYIQQLNKVSLRTSLI--GEEWPSPRNKSQSPDLTEKSNCHNKNWNDYSHQAFVYDHLSDLLELLLDPKQLTASFHSTHSSLVSREAVVALSFLIEGTISRARKIYPLHELALWQPLHADSGFSKISKTFSFYKLETWLRSCLTGNPFGTSACLKSGKKLAWA-------HQVEGTTKRAKI---ACNTHVAPRM----HRLVVMSQVYKQTLAKSSDTLAGAHVKIHRCNESFIYLLSPLRSVTIEKCRNSIFVLGPVGTTLHLHSCDNVKVIAVCHRLSISSTTGCIFHVLTPTRPLIL----------------------------SGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMV--VCRENSDTRVFQLLPPCEFYVFIIPFEMEGDTTEIPGGLPSVYQKALGQREQKIQIWQKTVKEAHLTKDQRKQFQVLVENKFYEWLINTGHRQQLDSLVP 547          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Human
Match: TBCCD1 (TBCC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25546])

HSP 1 Score: 264.618 bits (675), Expect = 1.443e-79
Identity = 160/480 (33.33%), Postives = 255/480 (53.12%), Query Frame = 2
Query:  458 SIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTK---KSIDM-EVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDP 1885
            S++  +F+L+LYIQQ+NK+SLR S +    EWP  +   +S D+ E     NKN ++  H  FV  ++ D++++L +P        +     +   A+ AL+ +I+G   +   I PL E+         +GFSK +KT S   L +W+RS L  NPF   ACL +GK+L W          + G+  + K    A   ++ P+     ++L+++S +  QT+A+SS TL  A +K+HRC+ S+ Y LSPLRSV+I+KCR S  +LGPV  T+ L +C++  ++A   RL +     C  + +T T PL+                               N+ + FAP+ + YP LE+H+++  +    N+W+ PMV  VC   +  ++++LLPP +FY   IPF+ EG TT  P   PS Y++AL QR  + +  +  +K + LT +Q K F+ LVE +F  WL  +   +QL  L P
Sbjct:   18 SVDTLQFLLFLYIQQLNKVSLRTSLI--GEEWPSPRNKSQSPDLTEKSNCHNKNWNDYSHQAFVYDHLSDLLELLLDPKQLTASFHSTHSSLVSREAVVALSFLIEGTISRARKIYPLHELALWQPLHADSGFSKISKTFSFYKLETWLRSCLTGNPFGTSACLKSGKKLAWA-------HQVEGTTKRAKI---ACNTHVAPRM----HRLVVMSQVYKQTLAKSSDTLAGAHVKIHRCNESFIYLLSPLRSVTIEKCRNSIFVLGPVGTTLHLHSCDNVKVIAVCHRLSISSTTGCIFHVLTPTRPLILSG----------------------------NQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMV--VCRENSDTRVFQLLPPCEFYVFIIPFEMEGDTTEIPGGLPSVYQKALGQREQKIQIWQKTVKEAHLTKDQRKQFQVLVENKFYEWLINTGHRQQLDSLVP 451          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Human
Match: TBCCD1 (TBCC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25546])

HSP 1 Score: 118.627 bits (296), Expect = 1.638e-29
Identity = 73/222 (32.88%), Postives = 119/222 (53.60%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTK---KSIDM-EVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNI 790
            LWV++EPF  G L V P P   S+H ++K+ +Y +++   G YP+L +  W+HIAC KLQL + L W  F     +S     +       L  C + EE E+ +N  S++  +F+L+LYIQQ+NK+SLR S +    EWP  +   +S D+ E     NKN ++  H  FV  ++ D++++L +P        +     +   A+ AL+ +I+G   +   I
Sbjct:    8 LWVKAEPFIVGALQVPP-PSKFSLHYLRKISTYVQIRATEGAYPRLYWSTWRHIACGKLQLAKDLAWLYFEIFDSLSMKTPEERLEWSEVLSNCMSEEEVEKQRNQLSVDTLQFLLFLYIQQLNKVSLRTSLI--GEEWPSPRNKSQSPDLTEKSNCHNKNWNDYSHQAFVYDHLSDLLELLLDPKQLTASFHSTHSSLVSREAVVALSFLIEGTISRARKI 226          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Human
Match: TBCCD1 (TBCC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25546])

HSP 1 Score: 82.4185 bits (202), Expect = 7.938e-18
Identity = 48/143 (33.57%), Postives = 71/143 (49.65%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTK 565
            LWV++EPF  G L V P P   S+H ++K+ +Y +++   G YP+L +  W+HIAC KLQL + L W  F     +S     +       L  C + EE E+ +N                Q+NK+SLR S +    EWP  +
Sbjct:    8 LWVKAEPFIVGALQVPP-PSKFSLHYLRKISTYVQIRATEGAYPRLYWSTWRHIACGKLQLAKDLAWLYFEIFDSLSMKTPEERLEWSEVLSNCMSEEEVEKQRN----------------QLNKVSLRTSLI--GEEWPSPR 131          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Zebrafish
Match: tbccd1 (TBCC domain containing 1 [Source:NCBI gene;Acc:100037389])

HSP 1 Score: 280.796 bits (717), Expect = 1.362e-84
Identity = 182/593 (30.69%), Postives = 310/593 (52.28%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTC-IIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSI--------DMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTT 1891
            +W R EPF  G+L   P P   SMH ++K+ SY + +    +P+L + +W+HIAC KLQL E L W  F T  ++M  +   +L+  E+ L  C   +E ++ +   S++  +F+L+LY+QQ+N+ISLR S +    EWP  +           D ++  S NKN D   HL F+  ++ +++++L EP    + G    D  +   A+E+L+L+++G    +  + P+ ++L  +    + GFSK + + S++    ++R  L  NPF +  C  +GK+L W L        + G+  + K  +    A         G++L+L+S +  QT+A+ S  L   ++KLHRC  ++ Y LSPL SV++DKCR ST++LGPV  ++ + +CE+  +V    RL + G   CTI+++T T PLL                               N  +   P+ + YPTLE+H++   +    N WN+P++ GV         + + PP++FYP+ IPF  +G     P   P ++++AL+ R    E  +  +K++ L   Q + F+ LVE++F  WL E+ + ++L  L P T
Sbjct:    8 VWPRLEPFLVGVLPATP-PSKFSMHYLRKMASYVRTR-DGCFPRLGWQMWRHIACGKLQLAEDLAWLYFETFDLLMPRSAEQRLEWAEA-LSQCHTQKELDRQRCKLSVDTLQFLLFLYLQQLNRISLRTSLI--GEEWPSPRSRSPSSSSSERDAKI-SSQNKNWDVQAHLTFIQTHLPELLELLVEPGQLSSSGQVLRDSHLTSEAVESLSLLLEGSVSHSRTVHPVHKLLSRSQLQSQAGFSKLSCSYSLQQFQDFLRQALCLNPFGISNCSQSGKKLSWALQ-------VEGTLKKAKIFRNTHAAP-------PGSRLVLMSQVCKQTLAKDSEKLNDVNIKLHRCSEAFIYLLSPLWSVTLDKCRNSTLVLGPVRTSVHIQSCENVRVVCVAGRLTIGGSFNCTIHSLTPTRPLLLPG----------------------------NASLTLGPFHTQYPTLEDHMASAGLAVVPNLWNQPLLFGVEGSAPDTGCYRIQPPSEFYPLVIPFQMDGDNCESPCSLPEDFQKALESREKTIEEWQKTVKDAHLNKAQRRQFQALVEQKFHEWLLETGQRQELDSLLPPT 552          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Zebrafish
Match: tbccd1 (TBCC domain containing 1 [Source:NCBI gene;Acc:100037389])

HSP 1 Score: 279.641 bits (714), Expect = 4.596e-84
Identity = 181/593 (30.52%), Postives = 310/593 (52.28%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTC-IIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSI--------DMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTT 1891
            +W R EPF  G+L   P P   SMH ++K+ SY + +    +P+L + +W+HIAC KLQL E L W  F T  ++M  +   +L+  E+ L  C   +E ++ +   S++  +F+L+LY+QQ+N+ISLR S +    EWP  +           D ++  S NKN D   HL F+  ++ +++++L EP    + G    D  +   A+E+L+L+++G    +  + P+ ++L  +    + GFSK + + S++    ++R  L  NPF +  C  +GK+L W L        + G+  + K  +    A         G++L+++S +  QT+A+ S  L   ++KLHRC  ++ Y LSPL SV++DKCR ST++LGPV  ++ + +CE+  +V    RL + G   CTI+++T T PLL                               N  +   P+ + YPTLE+H++   +    N WN+P++ GV         + + PP++FYP+ IPF  +G     P   P ++++AL+ R    E  +  +K++ L   Q + F+ LVE++F  WL E+ + ++L  L P T
Sbjct:    8 VWPRLEPFLVGVLPATP-PSKFSMHYLRKMASYVRTR-DGCFPRLGWQMWRHIACGKLQLAEDLAWLYFETFDLLMPRSAEQRLEWAEA-LSQCHTQKELDRQRCKLSVDTLQFLLFLYLQQLNRISLRTSLI--GEEWPSPRSRSPSSSSSERDAKI-SSQNKNWDVQAHLTFIQTHLPELLELLVEPGQLSSSGQVLRDSHLTSEAVESLSLLLEGSVSHSRTVHPVHKLLSRSQLQSQAGFSKLSCSYSLQQFQDFLRQALCLNPFGISNCSQSGKKLSWALQ-------VEGTLKKAKIFRNTHAAP-------PGSRLVVMSQVCKQTLAKDSEKLNDVNIKLHRCSEAFIYLLSPLWSVTLDKCRNSTLVLGPVRTSVHIQSCENVRVVCVAGRLTIGGSFNCTIHSLTPTRPLLLPG----------------------------NASLTLGPFHTQYPTLEDHMASAGLAVVPNLWNQPLLFGVEGSAPDTGCYRIQPPSEFYPLVIPFQMDGDNCEIPCSLPEDFQKALESREKTIEEWQKTVKDAHLNKAQRRQFQALVEQKFHEWLLETGQRQELDSLLPPT 552          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Zebrafish
Match: tbccd1 (TBCC domain containing 1 [Source:NCBI gene;Acc:100037389])

HSP 1 Score: 279.641 bits (714), Expect = 4.596e-84
Identity = 181/593 (30.52%), Postives = 310/593 (52.28%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTC-IIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSI--------DMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTT 1891
            +W R EPF  G+L   P P   SMH ++K+ SY + +    +P+L + +W+HIAC KLQL E L W  F T  ++M  +   +L+  E+ L  C   +E ++ +   S++  +F+L+LY+QQ+N+ISLR S +    EWP  +           D ++  S NKN D   HL F+  ++ +++++L EP    + G    D  +   A+E+L+L+++G    +  + P+ ++L  +    + GFSK + + S++    ++R  L  NPF +  C  +GK+L W L        + G+  + K  +    A         G++L+++S +  QT+A+ S  L   ++KLHRC  ++ Y LSPL SV++DKCR ST++LGPV  ++ + +CE+  +V    RL + G   CTI+++T T PLL                               N  +   P+ + YPTLE+H++   +    N WN+P++ GV         + + PP++FYP+ IPF  +G     P   P ++++AL+ R    E  +  +K++ L   Q + F+ LVE++F  WL E+ + ++L  L P T
Sbjct:    8 VWPRLEPFLVGVLPATP-PSKFSMHYLRKMASYVRTR-DGCFPRLGWQMWRHIACGKLQLAEDLAWLYFETFDLLMPRSAEQRLEWAEA-LSQCHTQKELDRQRCKLSVDTLQFLLFLYLQQLNRISLRTSLI--GEEWPSPRSRSPSSSSSERDAKI-SSQNKNWDVQAHLTFIQTHLPELLELLVEPGQLSSSGQVLRDSHLTSEAVESLSLLLEGSVSHSRTVHPVHKLLSRSQLQSQAGFSKLSCSYSLQQFQDFLRQALCLNPFGISNCSQSGKKLSWALQ-------VEGTLKKAKIFRNTHAAP-------PGSRLVVMSQVCKQTLAKDSEKLNDVNIKLHRCSEAFIYLLSPLWSVTLDKCRNSTLVLGPVRTSVHIQSCENVRVVCVAGRLTIGGSFNCTIHSLTPTRPLLLPG----------------------------NASLTLGPFHTQYPTLEDHMASAGLAVVPNLWNQPLLFGVEGSAPDTGCYRIQPPSEFYPLVIPFQMDGDNCEIPCSLPEDFQKALESREKTIEEWQKTVKDAHLNKAQRRQFQALVEQKFHEWLLETGQRQELDSLLPPT 552          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Zebrafish
Match: rp2 (RP2 activator of ARL3 GTPase [Source:NCBI gene;Acc:406755])

HSP 1 Score: 49.6766 bits (117), Expect = 8.360e-6
Identity = 20/98 (20.41%), Postives = 46/98 (46.94%), Query Frame = 2
Query: 1076 KLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYP 1369
            K  +++ + ++T+ R  G L      +  C     + L    +++ID C    ++LGPV+ ++   +C+D   V   ++     C++  ++   +T P
Sbjct:   63 KDFMLTGLKNETVGRLPGKLNGQQFVIQDCENCNIFVLDHSATITIDDCVNCRIVLGPVKGSVFFRDCKDIKCVVACQQFRTRDCKKMDVFLCCATQP 160          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Zebrafish
Match: rp2 (RP2 activator of ARL3 GTPase [Source:NCBI gene;Acc:406755])

HSP 1 Score: 49.6766 bits (117), Expect = 8.360e-6
Identity = 20/98 (20.41%), Postives = 46/98 (46.94%), Query Frame = 2
Query: 1076 KLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYP 1369
            K  +++ + ++T+ R  G L      +  C     + L    +++ID C    ++LGPV+ ++   +C+D   V   ++     C++  ++   +T P
Sbjct:   63 KDFMLTGLKNETVGRLPGKLNGQQFVIQDCENCNIFVLDHSATITIDDCVNCRIVLGPVKGSVFFRDCKDIKCVVACQQFRTRDCKKMDVFLCCATQP 160          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Xenopus
Match: tbccd1 (TBCC domain containing 1 [Source:NCBI gene;Acc:549715])

HSP 1 Score: 297.745 bits (761), Expect = 4.189e-91
Identity = 171/584 (29.28%), Postives = 293/584 (50.17%), Query Frame = 2
Query:  128 TNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSIDMEVCKSA--NKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQL 1870
            + +QLWV+++PF  G L + P P   SMH ++K+ +Y + +   G YP+L + +W+HIAC KLQ+ E   W  F T + +   +  +  N       C + E+ E+VK+  S++  +F+L+LYIQQINKISLR+  +      P  +  I     +S+  NK  D+  H  F+  ++  I+++L EP              +    + AL  +I+G  +KN  +    ++       +K+GF +T  + S + L +WI+  L  NPF + +C+ +G +L W    +  ++          + K+A     +P      ++++++S I+ QT+A+SS TL  A +K+HRC   Y Y LSPLRSV+++KC+  T++LGPV+  + +  C +  I+A  +RL L+    CT + +T T PL                                N+ +  AP+   Y  LE+H++   +    N W++P         +   IW LL P +F+   +PF+ EG TT  P   P  Y  +++QR  +    +  +K++ LT EQ K  + +VE +F  WL +++   QL
Sbjct:    4 SRVQLWVKTDPFLLGALQIPP-PEKFSMHYLRKMATYVRTRASEGCYPRLCWCMWRHIACGKLQILEETAWLYFETFLSVFERSVAESLNWAEVASTCPSSEKYEEVKSKLSVDTLKFMLFLYIQQINKISLRSPLIGNEWPSPRGRSPISDFAAQSSFYNKVWDDYSHYNFIHNHLTYILELLMEPNQLSKVSQFSHCILISAEVVTALGFVIEGTVDKNRVVNAFLDLAIWQPVQIKSGFIETLGSFSFQKLQAWIKECLVINPFGITSCIKSGTKLSWAQQVDGLNK----------RAKVACNTYKVP----HTHRMVVMSQISKQTLAKSSKTLVDARVKIHRCSDCYIYLLSPLRSVTVEKCQNCTIVLGPVQTVLHIQMCYNVKIIAVCQRLSLLSTTNCTFHVLTPTRPLFYCG----------------------------NQGVVLAPFHISYSMLEDHMAHTGLATVPNSWDRPFFFST--ESSNSHIWRLLLPEEFFTFVVPFEMEGDTTEIPGGLPPAYSTSVQQRQQKIRMWQETVKDAGLTREQRKQLQAVVEMKFNEWLIKTENRHQL 542          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Xenopus
Match: tbccd1 (TBCC domain containing 1 [Source:NCBI gene;Acc:549715])

HSP 1 Score: 161.384 bits (407), Expect = 1.216e-43
Identity = 86/281 (30.60%), Postives = 148/281 (52.67%), Query Frame = 2
Query:  128 TNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSIDMEVCKSA--NKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLW 961
            + +QLWV+++PF  G L + P P   SMH ++K+ +Y + +   G YP+L + +W+HIAC KLQ+ E   W  F T + +   +  +  N       C + E+ E+VK+  S++  +F+L+LYIQQINKISLR+  +      P  +  I     +S+  NK  D+  H  F+  ++  I+++L EP              +    + AL  +I+G  +KN  +    ++       +K+GF +T  + S + L +WI+  L  NPF + +C+ +G +L W
Sbjct:    4 SRVQLWVKTDPFLLGALQIPP-PEKFSMHYLRKMATYVRTRASEGCYPRLCWCMWRHIACGKLQILEETAWLYFETFLSVFERSVAESLNWAEVASTCPSSEKYEEVKSKLSVDTLKFMLFLYIQQINKISLRSPLIGNEWPSPRGRSPISDFAAQSSFYNKVWDDYSHYNFIHNHLTYILELLMEPNQLSKVSQFSHCILISAEVVTALGFVIEGTVDKNRVVNAFLDLAIWQPVQIKSGFIETLGSFSFQKLQAWIKECLVINPFGITSCIKSGTKLSW 283          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Xenopus
Match: pdia6 (protein disulfide isomerase family A member 6 [Source:Xenbase;Acc:XB-GENE-974680])

HSP 1 Score: 56.225 bits (134), Expect = 1.057e-7
Identity = 44/196 (22.45%), Postives = 69/196 (35.20%), Query Frame = 2
Query: 1076 KLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPP----ADFYPI 1651
            K  + S + DQT+ +    +      +  C     Y      +++ID C    + LGPV+ ++   +C+DC  V   ++     CRR  ++   ST P                          ++T   F    CF  Y   YP L     +  +    N W+         G T    W LLPP     DF P+
Sbjct:   45 KDYMFSGLKDQTVGKLPDKVAGQQFVIQECENCNIYIFDHSATITIDDCTNCRIFLGPVKGSVFFRDCKDCKCVVACQQFRTRDCRRMDVFLCCSTQP-----------------------IIESSTGMKFG---CFQYY---YPELALQFKEAGLSIFNNTWSNIHDFTPVAGETN---WSLLPPDSVIQDFIPL 208          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Mouse
Match: Tbccd1 (TBCC domain containing 1 [Source:MGI Symbol;Acc:MGI:1917823])

HSP 1 Score: 328.946 bits (842), Expect = 4.010e-103
Identity = 197/592 (33.28%), Postives = 320/592 (54.05%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKL--KNLE-SKLFA-CENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSID----MEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPT 1888
            LWV++EPF  G L   P P   S+H ++K+ +Y + +   G YP L +P W+HIAC KLQL + L W  F     M +N S++   + LE S++ + C   EE E+ ++   ++  +F+L+LYIQQ+N+ISLR S +    EWP  +         E     NKN ++  H  FV  ++ +++++L +P        +     +  +A+ AL+ +I+G   +   + PL ++       + +GFSK++KT S+  L +W+R++L +NPF   ACL +GK+L W          + GS  + K    A  A++ P+     ++++++S +  QT+A+SS TL  A ++ HRC  S+ Y LSPLRS++I+KCR ST +LGPVE T+ L +CE+  ++A   RL +     CT + +T + PL+                             + N+ + FAP+ + YP LE+H+++  +    N+W+ PMV  VC   +   ++ LLPP++FY   IPF+ EG T   P   PS Y++AL QR       +  +K ++LT EQ K F+ LVE +F  WL  +   +QL  L PT
Sbjct:    8 LWVKAEPFLVGALQ-EPPPSKFSLHYLRKIATYVRTRATEGAYPHLYWPTWRHIACGKLQLAKDLAWLYFE----MFDNLSVRTPEERLEWSEILSNCATEEEVEKQRSQLYVDTLQFLLFLYIQQLNRISLRTSLI--GEEWPSRRSRPQSPSPAERPSCHNKNWNDYSHQAFVCNHLSELLELLLDPEQLTASFHSTHSSLLSRDAVTALSFLIEGTVSRAKKVYPLHQLALWQPLHVASGFSKSSKTFSLYKLEAWLRASLTTNPFGPSACLKSGKKLAW-------AHQVEGSTKRAKI---ACNAHMAPRL----HRIVVMSQVYKQTLAKSSETLVGAHVRAHRCSESFIYLLSPLRSMTIEKCRNSTFVLGPVETTLHLHDCENLKVIAVCHRLSISSTTSCTFHIMTPSRPLIL----------------------------SGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMV--VCKEGSVTSLFRLLPPSEFYIFVIPFEMEGDTAEIPGGLPSAYQKALAQREESIHIWQKTVKEARLTKEQRKQFQALVENKFYEWLVSTGHRQQLDSLVPT 548          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Mouse
Match: Tbccd1 (TBCC domain containing 1 [Source:MGI Symbol;Acc:MGI:1917823])

HSP 1 Score: 328.946 bits (842), Expect = 4.010e-103
Identity = 197/592 (33.28%), Postives = 320/592 (54.05%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKL--KNLE-SKLFA-CENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSID----MEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPT 1888
            LWV++EPF  G L   P P   S+H ++K+ +Y + +   G YP L +P W+HIAC KLQL + L W  F     M +N S++   + LE S++ + C   EE E+ ++   ++  +F+L+LYIQQ+N+ISLR S +    EWP  +         E     NKN ++  H  FV  ++ +++++L +P        +     +  +A+ AL+ +I+G   +   + PL ++       + +GFSK++KT S+  L +W+R++L +NPF   ACL +GK+L W          + GS  + K    A  A++ P+     ++++++S +  QT+A+SS TL  A ++ HRC  S+ Y LSPLRS++I+KCR ST +LGPVE T+ L +CE+  ++A   RL +     CT + +T + PL+                             + N+ + FAP+ + YP LE+H+++  +    N+W+ PMV  VC   +   ++ LLPP++FY   IPF+ EG T   P   PS Y++AL QR       +  +K ++LT EQ K F+ LVE +F  WL  +   +QL  L PT
Sbjct:    8 LWVKAEPFLVGALQ-EPPPSKFSLHYLRKIATYVRTRATEGAYPHLYWPTWRHIACGKLQLAKDLAWLYFE----MFDNLSVRTPEERLEWSEILSNCATEEEVEKQRSQLYVDTLQFLLFLYIQQLNRISLRTSLI--GEEWPSRRSRPQSPSPAERPSCHNKNWNDYSHQAFVCNHLSELLELLLDPEQLTASFHSTHSSLLSRDAVTALSFLIEGTVSRAKKVYPLHQLALWQPLHVASGFSKSSKTFSLYKLEAWLRASLTTNPFGPSACLKSGKKLAW-------AHQVEGSTKRAKI---ACNAHMAPRL----HRIVVMSQVYKQTLAKSSETLVGAHVRAHRCSESFIYLLSPLRSMTIEKCRNSTFVLGPVETTLHLHDCENLKVIAVCHRLSISSTTSCTFHIMTPSRPLIL----------------------------SGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMV--VCKEGSVTSLFRLLPPSEFYIFVIPFEMEGDTAEIPGGLPSAYQKALAQREESIHIWQKTVKEARLTKEQRKQFQALVENKFYEWLVSTGHRQQLDSLVPT 548          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Mouse
Match: Tbccd1 (TBCC domain containing 1 [Source:MGI Symbol;Acc:MGI:1917823])

HSP 1 Score: 159.458 bits (402), Expect = 3.429e-43
Identity = 94/283 (33.22%), Postives = 158/283 (55.83%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKL--KNLE-SKLFA-CENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSID----MEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLW 961
            LWV++EPF  G L   P P   S+H ++K+ +Y + +   G YP L +P W+HIAC KLQL + L W  F     M +N S++   + LE S++ + C   EE E+ ++   ++  +F+L+LYIQQ+N+ISLR S +    EWP  +         E     NKN ++  H  FV  ++ +++++L +P        +     +  +A+ AL+ +I+G   +   + PL ++       + +GFSK++KT S+  L +W+R++L +NPF   ACL +GK+L W
Sbjct:    8 LWVKAEPFLVGALQ-EPPPSKFSLHYLRKIATYVRTRATEGAYPHLYWPTWRHIACGKLQLAKDLAWLYFE----MFDNLSVRTPEERLEWSEILSNCATEEEVEKQRSQLYVDTLQFLLFLYIQQLNRISLRTSLI--GEEWPSRRSRPQSPSPAERPSCHNKNWNDYSHQAFVCNHLSELLELLLDPEQLTASFHSTHSSLLSRDAVTALSFLIEGTVSRAKKVYPLHQLALWQPLHVASGFSKSSKTFSLYKLEAWLRASLTTNPFGPSACLKSGKKLAW 283          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Mouse
Match: Tbccd1 (TBCC domain containing 1 [Source:MGI Symbol;Acc:MGI:1917823])

HSP 1 Score: 108.227 bits (269), Expect = 3.281e-26
Identity = 64/175 (36.57%), Postives = 97/175 (55.43%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKL--KNLE-SKLFA-CENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSID----MEVCKSANKNMDEIQHLQFV 637
            LWV++EPF  G L   P P   S+H ++K+ +Y + +   G YP L +P W+HIAC KLQL + L W  F     M +N S++   + LE S++ + C   EE E+ ++   ++  +F+L+LYIQQ+N+ISLR S +    EWP  +         E     NKN ++  H  FV
Sbjct:    8 LWVKAEPFLVGALQ-EPPPSKFSLHYLRKIATYVRTRATEGAYPHLYWPTWRHIACGKLQLAKDLAWLYFE----MFDNLSVRTPEERLEWSEILSNCATEEEVEKQRSQLYVDTLQFLLFLYIQQLNRISLRTSLI--GEEWPSRRSRPQSPSPAERPSCHNKNWNDYSHQAFV 175          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Mouse
Match: Tbccd1 (TBCC domain containing 1 [Source:MGI Symbol;Acc:MGI:1917823])

HSP 1 Score: 73.1738 bits (178), Expect = 3.529e-15
Identity = 41/109 (37.61%), Postives = 63/109 (57.80%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKL--KNLE-SKLFA-CENPEEQEQVKN 451
            LWV++EPF  G L   P P   S+H ++K+ +Y + +   G YP L +P W+HIAC KLQL + L W  F     M +N S++   + LE S++ + C   EE E+ ++
Sbjct:    8 LWVKAEPFLVGALQ-EPPPSKFSLHYLRKIATYVRTRATEGAYPHLYWPTWRHIACGKLQLAKDLAWLYFE----MFDNLSVRTPEERLEWSEILSNCATEEEVEKQRS 111          
BLAST of TBCC domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q5FVR8|TBCC1_RAT (TBCC domain-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Tbccd1 PE=2 SV=1)

HSP 1 Score: 331.643 bits (849), Expect = 4.155e-103
Identity = 195/588 (33.16%), Postives = 311/588 (52.89%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKG-KAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDT----KKSIDMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGD-KIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDP 1885
            LWV++EPF  G L   P P  LS+H +KK+ +Y + +  +  YP+L +P W+HIAC KLQL + L W  F     +S     +       L  C   +E E+ +N  S++  +F+L+LYIQQ+NKISLR S +    EWP      K     E     NKN ++  H  FV  ++ +++++L +P        +     +   A+ AL+ +I+G   +   + PL E+          GFSK +KT S+  L +W+R+ L +NPF + ACL +GK+L W          + G+  + K    A  A++ P+     ++++++S + +QT+A+SS TL  A ++ HRC+ S+ Y LSPLRS++I+KCR ST +LGPVE  + L  CE+  ++A   RL +     CT + +T + PL+                             + N+ + FAP+ + YP LE+H+++  +    N+W+ PMV+G   G   D ++++LLPP++FY    PF+ EG T   P   P  Y++AL  R  R  N +  +K ++LT EQ K F+ LVE +F  WL  +   +QL  L P
Sbjct:    8 LWVKAEPFIVGALQ-EPPPSKLSLHYLKKVAAYVRTRATERAYPRLYWPTWRHIACGKLQLAKDLAWLYFEIFDNLSERTPEERLEWSEILSNCTTKDEVEKQRNQLSVDTLQFLLFLYIQQLNKISLRTSFI--GEEWPSPRNRPKSPSPAERSSCHNKNWNDYNHQAFVCDHLSELLELLLDPEQLTESFHSTQSSLLSREAVTALSFLIEGTVSRTKKVYPLHELALWQPLHAANGFSKISKTFSLYKLEAWLRACLTTNPFGLSACLQSGKKLAWA-------HKVEGATKRAKI---ACNAHMAPR----SHRIVVMSQVCNQTLAKSSETLVGAHVRAHRCNESFIYLLSPLRSMTIEKCRNSTFVLGPVETALHLHGCENLKVIAVCHRLSVSSTIGCTFHIMTPSRPLIL----------------------------SGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDDPMVLG---GEGTDTRVFQLLPPSEFYVFVTPFEMEGDTAEIPGGLPPAYQKALAHREQRIHNWQKTVKEARLTKEQRKQFQVLVENKFYEWLVSTGHRQQLDSLVP 547          
BLAST of TBCC domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9NVR7|TBCC1_HUMAN (TBCC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TBCCD1 PE=1 SV=1)

HSP 1 Score: 330.487 bits (846), Expect = 8.088e-103
Identity = 198/587 (33.73%), Postives = 313/587 (53.32%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTK---KSIDM-EVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDP 1885
            LWV++EPF  G L V P P   S+H ++K+ +Y +++   G YP+L +  W+HIAC KLQL + L W  F     +S     +       L  C + EE E+ +N  S++  +F+L+LYIQQ+NK+SLR S +    EWP  +   +S D+ E     NKN ++  H  FV  ++ D++++L +P        +     +   A+ AL+ +I+G   +   I PL E+         +GFSK +KT S   L +W+RS L  NPF   ACL +GK+L W          + G+  + K    A   ++ P+     ++L+++S +  QT+A+SS TL  A +K+HRC+ S+ Y LSPLRSV+I+KCR S  +LGPV  T+ L +C++  ++A   RL +     C  + +T T PL+                             + N+ + FAP+ + YP LE+H+++  +    N+W+ PMV  VC   +  ++++LLPP +FY   IPF+ EG TT  P   PS Y++AL QR  + +  +  +K + LT +Q K F+ LVE +F  WL  +   +QL  L P
Sbjct:    8 LWVKAEPFIVGALQVPP-PSKFSLHYLRKISTYVQIRATEGAYPRLYWSTWRHIACGKLQLAKDLAWLYFEIFDSLSMKTPEERLEWSEVLSNCMSEEEVEKQRNQLSVDTLQFLLFLYIQQLNKVSLRTSLI--GEEWPSPRNKSQSPDLTEKSNCHNKNWNDYSHQAFVYDHLSDLLELLLDPKQLTASFHSTHSSLVSREAVVALSFLIEGTISRARKIYPLHELALWQPLHADSGFSKISKTFSFYKLETWLRSCLTGNPFGTSACLKSGKKLAWA-------HQVEGTTKRAKI---ACNTHVAPRM----HRLVVMSQVYKQTLAKSSDTLAGAHVKIHRCNESFIYLLSPLRSVTIEKCRNSIFVLGPVGTTLHLHSCDNVKVIAVCHRLSISSTTGCIFHVLTPTRPLIL----------------------------SGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMV--VCRENSDTRVFQLLPPCEFYVFIIPFEMEGDTTEIPGGLPSVYQKALGQREQKIQIWQKTVKEAHLTKDQRKQFQVLVENKFYEWLINTGHRQQLDSLVP 547          
BLAST of TBCC domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q640P7|TBCC1_MOUSE (TBCC domain-containing protein 1 OS=Mus musculus OX=10090 GN=Tbccd1 PE=1 SV=1)

HSP 1 Score: 328.946 bits (842), Expect = 2.805e-102
Identity = 197/592 (33.28%), Postives = 320/592 (54.05%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKL--KNLE-SKLFA-CENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSID----MEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPT 1888
            LWV++EPF  G L   P P   S+H ++K+ +Y + +   G YP L +P W+HIAC KLQL + L W  F     M +N S++   + LE S++ + C   EE E+ ++   ++  +F+L+LYIQQ+N+ISLR S +    EWP  +         E     NKN ++  H  FV  ++ +++++L +P        +     +  +A+ AL+ +I+G   +   + PL ++       + +GFSK++KT S+  L +W+R++L +NPF   ACL +GK+L W          + GS  + K    A  A++ P+     ++++++S +  QT+A+SS TL  A ++ HRC  S+ Y LSPLRS++I+KCR ST +LGPVE T+ L +CE+  ++A   RL +     CT + +T + PL+                             + N+ + FAP+ + YP LE+H+++  +    N+W+ PMV  VC   +   ++ LLPP++FY   IPF+ EG T   P   PS Y++AL QR       +  +K ++LT EQ K F+ LVE +F  WL  +   +QL  L PT
Sbjct:    8 LWVKAEPFLVGALQ-EPPPSKFSLHYLRKIATYVRTRATEGAYPHLYWPTWRHIACGKLQLAKDLAWLYFE----MFDNLSVRTPEERLEWSEILSNCATEEEVEKQRSQLYVDTLQFLLFLYIQQLNRISLRTSLI--GEEWPSRRSRPQSPSPAERPSCHNKNWNDYSHQAFVCNHLSELLELLLDPEQLTASFHSTHSSLLSRDAVTALSFLIEGTVSRAKKVYPLHQLALWQPLHVASGFSKSSKTFSLYKLEAWLRASLTTNPFGPSACLKSGKKLAW-------AHQVEGSTKRAKI---ACNAHMAPRL----HRIVVMSQVYKQTLAKSSETLVGAHVRAHRCSESFIYLLSPLRSMTIEKCRNSTFVLGPVETTLHLHDCENLKVIAVCHRLSISSTTSCTFHIMTPSRPLIL----------------------------SGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMV--VCKEGSVTSLFRLLPPSEFYIFVIPFEMEGDTAEIPGGLPSAYQKALAQREESIHIWQKTVKEARLTKEQRKQFQALVENKFYEWLVSTGHRQQLDSLVPT 548          
BLAST of TBCC domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|A4IF93|TBCC1_BOVIN (TBCC domain-containing protein 1 OS=Bos taurus OX=9913 GN=TBCCD1 PE=2 SV=1)

HSP 1 Score: 325.479 bits (833), Expect = 8.819e-101
Identity = 196/593 (33.05%), Postives = 318/593 (53.63%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKG-KAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKL------FACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTK---KSIDM-EVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDP 1885
            LWV++EPF  G L + P P   S+H ++K+ +Y + +  + GYP+LS+  W+HIAC KLQL + L W  F         +S+ +K  E +L        C + +E E+ +N  S++  +F+L+L+IQQ+NK+SLR S +    EWP  +   +S D+ E     NKN ++  H  FV  ++ D++++L +P        +     +   A+ AL+ +I+G       I PL E+        +TGFSK +KT S   L +W+R+ L  NPF   ACL +GK+L W          + G+  + K    A   ++ P+     ++++++S +  QT+A+SS TL  A +K+HRC+ S+ Y LSPLRSV+I+KCR ST +LGPV+  + L +C++  ++A   RL +     C  + +T T PL+                             + N+ + FAP+ + YP LE+H+++  +    N+W+ PM+  VC   +   ++ LLPP +FY   IPF+ EG TT  P   PS Y++AL QR  + +  +  +K ++LT +Q K F+ LVE +F  WL  +   +QL  L P
Sbjct:    8 LWVKAEPFIVGALQIPP-PSKFSLHYLRKISTYVRTRTIEGGYPRLSWSTWRHIACGKLQLAKDLAWLYFEMF------DSLAMKTPEERLEWSEILSNCMSEDEVEKQRNQLSVDTLQFLLFLHIQQLNKVSLRTSLI--GEEWPSPRHRAQSPDLTEKSSCHNKNWNDYSHQAFVCDHLSDLLELLLDPEQLTASFHSTHSSLVSREAVVALSFLIEGTVSGARKIYPLYELALWHPLHAETGFSKASKTFSFYKLEAWLRTCLTGNPFGTSACLKSGKKLAWA-------HQVEGTTKRAKI---ACNTHVAPRM----HRMVVMSQVYKQTLAKSSDTLVGAHVKIHRCNESFIYLLSPLRSVTIEKCRNSTFVLGPVQTALHLHSCDNVKVIAVCHRLSISSTTGCIFHILTPTRPLIL----------------------------SGNQRVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMI--VCRENSSPSVFRLLPPCEFYVFIIPFEMEGDTTEIPGGLPSAYQKALSQRKKKIQVWQKTVKEARLTKDQRKQFQVLVENKFYEWLINTGHRQQLDSLVP 547          
BLAST of TBCC domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q08AV6|TBCC1_XENLA (TBCC domain-containing protein 1 OS=Xenopus laevis OX=8355 GN=tbccd1 PE=2 SV=1)

HSP 1 Score: 308.916 bits (790), Expect = 1.300e-94
Identity = 176/586 (30.03%), Postives = 300/586 (51.19%), Query Frame = 2
Query:  128 TNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAG-YPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPD--TKKSIDMEVCKSA--NKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQL 1870
            + +QLW +++PF  G L + P P   SMH ++K+ SY + +   G YP+L + +W+HIAC KLQ+ E   W  F T + +   +  +  +       C + E+ E++K+  S++  +F+L+LYIQQINKISLRA  +   +EWP   ++      V +S+  NK  D+  H  F+  ++  I+++L EP        +     +    + AL  +I+G  +KN  +    ++       +K+GF +T+   S + L +WI+  L  NPF + AC+ +G +L W    +  ++          + K+A     +P      ++++++S I+ QT+A+SS TL  A +K+HRC   Y Y LSPLRSV+++KC+  T+ILGPV+  + +  C +  I+A  +RL L+    CT + +T T PL                                N+    AP+   Y  LE+H+++  +    N W++P +           IW L+PP DF+   +PF+ EG TT  P   P  Y  +++QR  +    +  +K++ LT EQ K F+ +VE +F  WL++++   QL
Sbjct:    4 SRVQLWAKTDPFLLGALQMPP-PAKFSMHYLRKMASYVRTRATEGCYPRLYWAMWRHIACGKLQIVEETAWLYFETFLSVFERSVAQSLDWAEVASTCPSSEKYEEIKSQLSVDTLKFILFLYIQQINKISLRAPMI--ESEWPSPRSRSPTPDFVAQSSIYNKVWDDYSHYNFIHNHLTYILELLMEPKQLSIVTQSSHCILISAEVVNALGFLIEGTVDKNRAVNHFLDLAVWQPVQIKSGFIETSGAFSFQKLQAWIKECLVINPFGITACIKSGTKLSWAQQVDGLNK----------RAKVACNTYKVP----HTHRMVVMSQISKQTLAKSSKTLVDARVKIHRCSDCYIYLLSPLRSVTVEKCQNCTIILGPVQTVLHIQMCYNVKIIAVCQRLSLLSTTNCTFHILTPTRPLFYCG----------------------------NQGAVLAPFHIRYSMLEDHMAQTGLATVPNSWDRPFLFST--ESNNSNIWRLMPPEDFFTFVVPFEMEGDTTEIPGGLPPAYSNSVQQRQQKIHTWQKTVKDAGLTREQRKQFQAVVEMKFNEWLSKTENRHQL 542          
BLAST of TBCC domain-containing protein 1 vs. TrEMBL
Match: A0A504YPK3 (TBCC domain-containing protein 1 OS=Fasciola gigantica OX=46835 GN=FGIG_08936 PE=4 SV=1)

HSP 1 Score: 496.123 bits (1276), Expect = 1.360e-161
Identity = 283/695 (40.72%), Postives = 399/695 (57.41%), Query Frame = 2
Query:  110 MSTSSSTNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWP---------DTKKSIDMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXX-------XXXXXXXATTANLLPKEFGK-GNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYP-----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIG-------------VCLGPTGDKIWELLPPADFYPITIP------FDFEGPT-----------------------------------------------TSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTTS 1894
            M+  +   + LW R+EPFTYGI  V+PHPRL ++HNIKKLVSYAK KGK G+PKLSY +WKH+ACNKLQL+E L W LFHTC+ M N +  K+K++E +LF+  N  E ++++  QS++LF FVL+LYIQQINKISLRASAVS NAEWP         D+ +S  +  C+    N+DE  HL F+  N+ +++D+L EP   D  G N  D  +  +AI+ALNLII+G  ++  ++   SE++++ + +  TG+SKTT+T +++ L SWIRS L  NPFSVE C+ NG+RL W L    G E +  +           K+Q+IAT A+ +P+  G+ GNKL+++S I+ Q IARSS TL+ A+LK+HR H SY Y LSP+RSV++DKCRK T++LGP+ENT+QL +CEDC+IV+  RR VL+ CRRCT++   S+ P                   +       S+    +S     + +   TQ  NE+I  APY + Y  L +H+ +V +  K+N+W+KP ++G               L   G + W+LL P  FYP  IP       +   PT                                               T  P P P  Y  AL +R+  Y+     I N++LT EQ + F  LV++RFR+WL ES   RQL LL+ +T 
Sbjct:    1 MAKPTHPAVSLWPRAEPFTYGIFQVHPHPRL-AVHNIKKLVSYAKSKGKTGFPKLSYSVWKHVACNKLQLSEELAWVLFHTCLAMCNYHMEKMKDMEERLFSAANSAEFDRLRGMQSVDLFTFVLFLYIQQINKISLRASAVSANAEWPSSHNRSSELDSGRSTPIRPCR----NLDEQYHLLFITENLAELLDLLIEP---DLYGINNIDASLSEDAIDALNLIIEGTVDQCRSLNSFSELVRMPAISPATGYSKTTRTYNIRGLHSWIRSWLSPNPFSVENCIRNGRRLQWRLPYQAGMEGVPSTNAGNQHQQDTSKRQRIATNAHQVPRNGGRNGNKLVIMSMISRQIIARSSATLDGATLKIHRAHCSYLYLLSPMRSVTLDKCRKLTIVLGPIENTLQLNHCEDCLIVSACRRAVLVACRRCTLHLSISSRPILIQPPMPSGNTATSSSSAATVGTGGLSAPSQTSSAPGTPTPAGGVTQLGNEEILLAPYHTTYLRLVDHMMRVCLSTKVNYWDKPFLLGQDSNRHDQIIQTSTALSGKG-RCWDLLRPEHFYPFNIPLLLPSRMEHPEPTGTNADGTDAVQRTASGLDLSAALVTDTHRFFKDADERGIKEYLAMVNTRLPIPLPMPYLIALHERAAVYQKWPQHIANARLTPEQRQVFGTLVDQRFRHWLAESGNLRQLQLLELSTG 686          
BLAST of TBCC domain-containing protein 1 vs. TrEMBL
Match: A0A4E0QUN2 (TBCC domain-containing protein 1 OS=Fasciola hepatica OX=6192 GN=D915_008655 PE=4 SV=1)

HSP 1 Score: 494.967 bits (1273), Expect = 4.631e-161
Identity = 284/695 (40.86%), Postives = 398/695 (57.27%), Query Frame = 2
Query:  110 MSTSSSTNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWP---------DTKKSIDMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXX-------XXXXXXXATTANLLPKEFGK-GNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYP-----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIG-------------VCLGPTGDKIWELLPPADFYPITI----PFDFEGP-------------------------------------------------TTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTTS 1894
            M+  +   + LW R+EPFTYGI  V+PHPRL ++HNIKKLVSYAK KGK G+PKLSY +WKH+ACNKLQL+E L W LFHTC+ M N +  K+K++E +LF   N  E ++++  QS++LF FVL+LYIQQINKISLRASAVS NAEWP         D+ +S  +  C+    N+DE  HL F+  N+ +++D+L EP   D  G N  D  +  +AI+ALNLII+G  ++  ++   SE++++ + +  TG+SKTT+T +++ L SWIRS L  NPFSVE C+ NG+RL W L    G E +  +           K+Q+IAT A+ +P+  G+ GNKL+++S I+ Q IARSS TL+ A+LK+HR H SY Y LSP+RSV++DKCRK T++LGP+ENT+QL +CEDC+IV+  RR VL+ CRRCT++   S+ P                   +       S+    +S     + +   TQ  NE+I  APY + Y  L +H+ +VS+  K+N+W+KP ++G               L   G + W+LL P  FYP  I    P   E P                                                  T  P P P  Y  AL +R+  Y+     I N++LT EQ + F  LV++RFR+WL ES   RQL LL+ +T 
Sbjct:    1 MAKPTHPAVSLWPRAEPFTYGIFQVHPHPRL-AVHNIKKLVSYAKSKGKTGFPKLSYSVWKHVACNKLQLSEELAWVLFHTCLAMCNYHMEKVKDMEERLFNAANSAEFDRLRGMQSVDLFTFVLFLYIQQINKISLRASAVSANAEWPSSHNRSSELDSGRSTPIRPCR----NLDEQYHLLFITENLAELLDLLVEP---DLYGINNIDAGLSEDAIDALNLIIEGTVDQCRSLNSFSELVRMPAISPATGYSKTTRTYNLRGLHSWIRSWLSPNPFSVENCIRNGRRLQWRLPYQAGIEGVPSTNAGNQHQQDTSKRQRIATNAHQVPRNGGRNGNKLVIMSMISRQIIARSSATLDGATLKIHRAHCSYLYLLSPMRSVTLDKCRKLTIVLGPIENTLQLNHCEDCLIVSACRRAVLVACRRCTLHLSISSRPILIQPPMPSGNTATSSSSAATVGTGGLSAPSQTSSAPGTPTPAGGVTQLGNEEILLAPYHTTYLRLVDHMMRVSLSTKVNYWDKPFLLGQDSNRHDQIIQTSTALSGKG-RCWDLLRPEHFYPFNIPLLLPSRMEHPEPTGTNADGTDAVQRTASGLDLSAALVTDTHRFFKDADERGIKEYLAMVNTRLPIPLPMPYLIALHERAAVYQKWPQHIANARLTPEQRQVFGTLVDQRFRHWLAESGNLRQLQLLELSTG 686          
BLAST of TBCC domain-containing protein 1 vs. TrEMBL
Match: R7TY56 (C-CAP/cofactor C-like domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_226350 PE=4 SV=1)

HSP 1 Score: 451.44 bits (1160), Expect = 8.415e-147
Identity = 236/586 (40.27%), Postives = 351/586 (59.90%), Query Frame = 2
Query:  131 NLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSIDMEV----CKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDK--IWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQL 1870
             + LWV++EPFT G L V PH RL + HNIKK+VSYAK KGK GYP LSY +WKHIACNKLQL E + W  F T  ++ + ++     L+ K     +  E + +K   S+   +FVL+L+IQ + KISLRAS VS + EWP   +S D+E         NK++DE  H+ FVL N+ +I++++ EP  S + G N +D  + + A+EAL+ +I G  E +  +KPL +I  +      +G+SK +++ S ++L +W+RS++G NPF V +C+  G+RL WPL     +     ++   K+ +IAT A L+PK+  KGNKLIL+S +  QT+ RSSGTLE +++K+HRCH+SY Y LSPLRSVSI+KCR ST++LG V+  +QL +CE+  I+A  R  V      CT++ +T   P++                             + NE + F PY S+Y +LEEHL K  +    N W+KP+ IG       D+  +WE++ P DFY  ++PFD EGPT   P   P+ +++AL  R  + E  +  +K++ L+ EQ + F+ +VE RF+ WL E+   R+L
Sbjct:    7 QVALWVKAEPFTVGSLPVPPHARL-TTHNIKKIVSYAKNKGKLGYPNLSYSVWKHIACNKLQLPEDIAWMYFTTFDLLGSTSNEARLELDKKFARSSSQHEIDLLKCQLSVPTLQFVLFLHIQHMQKISLRASLVSGSDEWPTRSRSPDIEGRTTPTGGTNKSLDEHHHMTFVLNNLNEIMELMVEP-DSYSAGSNTNDLSLSIEAVEALDFLISGSLEGSRAVKPLHQIALMQQMHPTSGYSKISRSFSYRSLQTWLRSHIGQNPFGVSSCIAQGRRLSWPLAGEDKE-----ARADIKRGRIATNALLVPKDQTKGNKLILMSQVVRQTVGRSSGTLEGSTIKIHRCHFSYIYLLSPLRSVSIEKCRNSTILLGAVQTCVQLSHCENVTIIAACRTFVASASSNCTMHLMTPNTPIVC----------------------------SGNESLVFGPYHSYYGSLEEHLRKAGLSTLPNLWDKPLCIGT---DHQDEFPVWEIMNPKDFYVFSVPFDMEGPTKCIPGGLPARFQKALVSRERQIETWQKMVKDAGLSKEQKRQFQAVVESRFQEWLNETGHKREL 554          
BLAST of TBCC domain-containing protein 1 vs. TrEMBL
Match: A0A2T7PE68 (C-CAP/cofactor C-like domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_07132 PE=4 SV=1)

HSP 1 Score: 448.358 bits (1152), Expect = 1.763e-145
Identity = 245/599 (40.90%), Postives = 354/599 (59.10%), Query Frame = 2
Query:  122 SSTNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNN-SIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSIDMEVCKS--ANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMG---LNAIEALNLIIDGRTEKN---GNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTR----RLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDK---IWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQL 1870
            S T + LWV++EPF+YG L V PHPRL +  NIKK++ YAK KG AG+PKLSY +WKHIAC+K+QLTE L W  F TC  ++ +  +I+       +  C+ PEE    +   SI+  +FVLYLYIQ + K+SLRAS ++ + EWP    S+D++   +  ++K++D+  HL F+  NI +II++L+E   S +G  +++    G   L+A+EAL+ II G  EK+     I PL +I  + S    +G+SK TKT S++  L W++ NL  NP+SV AC+  G RL WP    +G+          K+ KIAT A ++PKE   GNKLI++S ++ QTIARSSGTLE++++K+HR H+SY Y LSPLRSV+++KCR +TV+LG +E  + + NCE   ++ P R    R V+ GC +CT Y +TS  PLL                             + N+ +  APY ++Y  LEEH+S   +   +N W+ P+    C+GP        WELLPPADF    IPF  +GPT S P   P  Y  A+ QR  + ++ +  +K + L  EQ + F+ LVE RF  WL E+   R+L
Sbjct:    2 SRTGVDLWVKAEPFSYGALPVAPHPRL-NFSNIKKILIYAKSKGSAGFPKLSYSVWKHIACHKMQLTEDLAWVYFETCYFLTTDMLAIERAERVKSIGDCKTPEEGVLQRAKYSIDTLKFVLYLYIQLLYKVSLRASLLAGD-EWPTQTMSLDLDGRSTPRSSKSLDDHSHLVFIQSNIAEIIELLSEQDASKSGSISENSTVHGSLSLSAVEALSFIITGCIEKSVEKKTIMPLQDIAVLQSIQYYSGYSKATKTFSLRQFLIWLKDNLIMNPYSVSACIALGTRLSWPFGG-EGERDATTVSTSTKRGKIATNAQIVPKEHVTGNKLIIMSQVSKQTIARSSGTLERSTIKIHRSHFSYIYLLSPLRSVTVEKCRNTTVVLGAIEAFVHISNCEGVTVICPCRSIMIRQVMDGCTQCTFYLLTSNRPLLL----------------------------SGNKKLMLAPYNTYYSHLEEHMSYAGLTASVNLWDNPL----CIGPDHSDETPAWELLPPADFGISVIPFQMDGPTKSIPGGLPGRYHRAVVQRQKQVDSWQRTVKEAGLNREQRREFQALVESRFHMWLAETGHKREL 565          
BLAST of TBCC domain-containing protein 1 vs. TrEMBL
Match: G4VAL0 (C-CAP/cofactor C-like domain-containing protein OS=Schistosoma mansoni OX=6183 GN=Smp_120920.2 PE=4 SV=1)

HSP 1 Score: 444.121 bits (1141), Expect = 3.319e-143
Identity = 258/621 (41.55%), Postives = 366/621 (58.94%), Query Frame = 2
Query:  110 MSTSSSTNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWP---------DTKKSIDMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLN-----------NNKGDEPIVGSXXXXXXXXXATTANLLPKEFGK-GNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQ-----------TFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGD-------KIWELLPPADFYPITIPFDFEGPTTSCP-TPWPSEY---EEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWL 1843
            M  +S   L LW R+EPF YGI  V+PHPRL ++HNIKKLV+YAK K K G  +LSY +WKH+ACNKLQLTE L W LFHTC+ MS     KLK+++ ++F   N  + E+++  QS+ LF FVL+LYIQQINKISLRASAVS +AEWP         D+ +S  + +C+    N+DE  H QF+  N+ +++D+L EP   D    N  D  +   A+EAL+L+++G  ++   +   SE+  I +    TG+SK T    ++ LLSWIRS L  NPFSVE C+ NG+RL W L            NN   +P        K+QKIAT A+ +P+  G  GNKL+++S I+ Q IARSS TL+ A+LK+HR H SY Y LSP+RSV++DKCRK T++LGP+ENT+QL +CEDC+++A  RR VL  CRRCT++    + P+L Q    NT S  +  SN    ++   T+              NE+I  AP+ + Y  L +HL+KV++ PK+N+W++P ++G               + W+LL PA FYP  IP        S    P    Y   EE++   + +  N      ++ L +  ++Y  +  E+R  N+L
Sbjct:    1 MGKASHVTLSLWPRAEPFAYGIFQVHPHPRL-AVHNIKKLVTYAKTKSKIG-SRLSYSVWKHVACNKLQLTEDLAWVLFHTCLTMSATQYEKLKDVDERIFTAANLADAERIRASQSVNLFTFVLFLYIQQINKISLRASAVSASAEWPGSYSRSSELDSGRSTPIRLCR----NLDEQYHFQFISENLNEMLDLLVEP---DNQSGNSMDATLSEGAVEALDLVLEGSADEGRTLNSFSELAHIPTILPATGYSKVTHAFHLRGLLSWIRSWLTQNPFSVENCILNGRRLQWRLPHQVVLDNESGLNNTQQQP---QNDVIKRQKIATNAHQVPRTGGHSGNKLVVMSMISRQIIARSSATLDGATLKIHRAHCSYLYLLSPMRSVTLDKCRKLTIVLGPIENTLQLNHCEDCLVIAACRRAVLASCRRCTLHLAIQSRPILIQPPVPNTISGSMIISNIPGNNSGTNTSTPGTPTPGSVALVGNEEILLAPFHTTYMKLVDHLNKVNLSPKVNYWDRPFLLGQDSSRQDSSQQLSRVRCWDLLQPAHFYPFNIPLLLSTRAESMDHNPVGKNYTRSEESVPNGNPQTANCLDL--SASLITNTSRYLGDSDERRLENYL 607          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Cavefish
Match: tbccd1 (TBCC domain containing 1 [Source:NCBI gene;Acc:103033584])

HSP 1 Score: 333.569 bits (854), Expect = 1.820e-104
Identity = 193/595 (32.44%), Postives = 322/595 (54.12%), Query Frame = 2
Query:  140 LWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSIDMEVCK------SANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGD-KIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTTSVHA 1903
            +W R EPF  G L V P P  LSMH ++K+  Y + + +  +P+LS+ +W+HIAC KLQL E L W  F T  ++      +       L   ++P E ++ ++   ++  +F+L+LY+QQ+N++SLR S +    EWP  +        +      S+NKN D+  H+ FV  ++ +++++L+EP    + G    D Q+   A++AL+L+++G T +   + P+  +L  A    + G+SKT+ T S++ L +W+R  L  NPF +  CL +GK+L W L        + G+  + K  +   TA  +P     G+K++++S +  QT+A+ S  L  A++KLHRC  ++ Y LSPLRSV++DKCR STV+LGPVE  + + +CE+  +V  T RLV+     CT++ +T T PLL                               N  +   P+ + YPTLE+H++ V +    N W+ P++ G   GP  D   + +LPP +F+ + +PF  EG T   P   P+ Y++A++ R    +  +  +K++ L  EQ + F+ LVE++F  WL E+ + ++L  L P T   A
Sbjct:    8 IWPRMEPFLLGALQVAP-PSKLSMHYLRKMACYVRTR-EGCFPQLSWHMWRHIACGKLQLAEELAWLYFETFDLLVPRAPEEKLEWAEALSQSQSPRELDRQRSKLCVDTLQFLLFLYMQQLNRVSLRTSMI--GEEWPSPRSRSSSLTSERETKTSSSNKNWDDQAHVTFVQTHLSELLELLSEPGEVSSSGQVLRDSQLPFEAVQALSLLLEGSTSRGRTVHPIHRLLSRAPLQSQAGYSKTSHTFSLQLLQNWLRQTLTLNPFGISTCLRSGKKLAWALQ-------VEGAMKRVKIARNTHTA--VP-----GSKVVVMSQVYKQTLAKDSEKLSGANVKLHRCSEAFIYLLSPLRSVTLDKCRNSTVVLGPVETNVHVQSCENVRLVCVTARLVIGASSHCTVHALTPTRPLLLPG----------------------------NTALTLGPFHTHYPTLEDHMASVGLAVVPNLWDLPLLYGPD-GPAPDPSCYRILPPEEFFLMVVPFQSEGDTCEVPGGLPAAYQQAVEARERSVQEWQRTVKDAHLNKEQRRQFQALVEQKFHEWLLETGQRQELDSLVPPTVAQA 555          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Cavefish
Match: rp2 (RP2 activator of ARL3 GTPase [Source:NCBI gene;Acc:406755])

HSP 1 Score: 50.0618 bits (118), Expect = 5.394e-6
Identity = 21/98 (21.43%), Postives = 44/98 (44.90%), Query Frame = 2
Query: 1076 KLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYP 1369
            K  +++ + D T+ R  G L      +  C     +      +V+ID C    ++LGPV+ ++   +C+D   V   ++     C++  ++   +T P
Sbjct:   37 KDFMLTGVKDATVGRLPGKLNGQQFVIQDCENCNIFVFDHSATVTIDDCVNCRIVLGPVKGSVFFRDCKDIKCVVACQQFRTRDCKKMDVFLCCATQP 134          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: TBCCD1 (TBCC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25546])

HSP 1 Score: 175.637 bits (444), Expect = 7.457e-50
Identity = 103/323 (31.89%), Postives = 155/323 (47.99%), Query Frame = 2
Query:  836 TGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFG--KGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGD----KIWELLPPADFYPITIPFDFEGPTTS-CPTPWPSEYEEALK---------QRSLRYENL 1756
            +GF    K  S++ L  W+R +L  +P+ + ACL  G+ L W  N                    A  A +L    G   G +++++   + QT+ARSS  L  A + +HRC  S+ Y LSPLRSVSI++CR++ ++LGPVE  + +  CED  +V   RRLV   C  CT + +T   P                            +  + +  I  APY + YP LEEH+++  +    N W++P+ +G   GP  D    K + LLPP++ + +T+PF   G TTS  P   P  YE AL          Q+++RY NL
Sbjct:    6 SGFLPGLKAFSLRPLQLWLRDHLNLSPYGMSACLQRGRHLSWAQNGEG----------------TAQRACMLRSGQGTPAGARVVMLRKASRQTLARSSPRLAGAHVCIHRCSDSFIYLLSPLRSVSIERCRRTVLVLGPVETHVTVHGCEDVTVVVACRRLVASACSACTFHLLTPCRP-------------------------LLVSAPSGDTGITLAPYHTHYPLLEEHMARAGLAAVPNRWDQPLCLG---GPEADGTNGKCYRLLPPSELHLLTVPFAIAGGTTSEVPGGLPGAYERALAARDQSVQAWQQTMRYANL 284          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO30525 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0J5])

HSP 1 Score: 321.627 bits (823), Expect = 9.689e-101
Identity = 200/603 (33.17%), Postives = 315/603 (52.24%), Query Frame = 2
Query:  125 STNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWP--------DTKKSIDMEVCKSANKN--MDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKN-----GNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHL-SKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDP 1885
            ST++ LWVR+EPF  G +HV P P  L++HN+ KL  Y++ KGKAGYPK+S+ +WKH+ACNKL L E   W  F T  ++S+++    +    +   C    E  Q++N  S+ L +FV++L+IQQI+KIS +AS VS   E+P        + + + D   CK  N     D +   Q   YN+ +I +I+   +T        ++  + L A++AL  +  G T+ N       I+ L ++ ++ S+  ++G+SK  ++ S +   +W+RS L  NP+ V   L+ GK        +KGD+ I  S I+ +     T  N  P       +L+++S I  QT+A++S T   ++LK+HRCHYSY Y L PLRSV+I KC  ST++LG V   + +  C++ + +  + ++ +  C  C+ +  T T PL+                             T NE +  APY +FYP LEEHL S   +    N WN P+++     P   +++  +P  DF+   IPF+ +G T   P P P +YE AL+ R          +K++ L   Q    + +V+KRF++WLTES    QL  L P
Sbjct:    3 STSVSLWVRAEPFDCGAIHV-PLPPKLTLHNLHKLSIYSRSKGKAGYPKISFSLWKHVACNKLGLKEDQAWMYFETFDMLSDSSFKNTQLWAKQSSQCRTQAEIAQLRNQVSVHLLQFVIFLFIQQIHKISFKASLVSGAEEYPLQFTSTQYNDRNTRDSVCCKQYNDRNTRDSVCCKQ---YNV-EIQEIVCAVSTV-------TESHLTLEAVDALGFLFIGTTDGNVIYLHRKIQQLQDLSRLQSEVNRSGYSKLCRSFSFRQFQTWLRSTLQINPYGVSEVLSQGK--------HKGDQSIKESSIKGRIM---TNVNFAPAV----QRLVIMSQICKQTVAKASDTYAGSNLKIHRCHYSYIYVLCPLRSVTITKCHDSTIVLGCVNTAVNIIGCQNVLFIMISNQVSMSACLNCSFHLCTPTRPLIL----------------------------TGNEGLTLAPYHTFYPKLEEHLKSPWGVATFPNEWNNPLLLDDSSCP---EVYREMPLEDFFTFNIPFNMKGSTDGSPIPLPEKYENALQDRENIISGWYQTVKDASLNKPQRAQLQGIVQKRFQDWLTESGNGSQLNGLVP 547          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO36223 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ71])

HSP 1 Score: 50.8322 bits (120), Expect = 1.010e-6
Identity = 38/198 (19.19%), Postives = 71/198 (35.86%), Query Frame = 2
Query: 1088 ISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPP----ADFYPITIPFDF 1669
            ++++ D T+ R  G +      +  CH    Y      +++ID C   T  LGP++ ++   +C +C +    ++     C++   + +  + P++  S                                 F  +  +YP LE    K S+    N W+    I       G+  W LLP      DF P+    +F
Sbjct:   35 LANLKDVTVGRLPGKVNGEGFVIQDCHDCNIYIFDNSATITIDDCVGCTFFLGPIKGSVFFRDCNNCKVAVACQQFRTRDCKKMDFFLLCDSQPIIESSSGMK-----------------------------FGCFQYYYPELEGQFEKASLSVYNNNWSN---IYDFTPAAGETTWSLLPENSKVEDFIPLPTTEEF 200          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Medaka
Match: rp2 (RP2 activator of ARL3 GTPase [Source:NCBI gene;Acc:101168112])

HSP 1 Score: 51.9878 bits (123), Expect = 1.653e-6
Identity = 41/195 (21.03%), Postives = 70/195 (35.90%), Query Frame = 2
Query: 1088 ISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPA----DFYPITIP 1660
            +  + D T+ R  GTL      +  C     + L    +++ID C    ++LGPV+ ++   +C+D   V   ++     C++  ++   +T P++  S                                 F  +  FYP L  H     +    N W+    I      +G+  W LLP A    DF P   P
Sbjct:   57 LKELKDVTVGRLPGTLNGEQFVIQECENCNIFVLDHSATITIDDCVNCRIVLGPVKGSVFFRDCKDIKCVVACQQFRTRDCQKMDVFLCCATQPIIESSTGMK-----------------------------FGCFQYFYPELAFHFKDAGLSIFNNNWSN---IHDFTPVSGENNWSLLPEASSVLDFVPTPDP 219          
BLAST of TBCC domain-containing protein 1 vs. Ensembl Medaka
Match: rp2 (RP2 activator of ARL3 GTPase [Source:NCBI gene;Acc:101168112])

HSP 1 Score: 51.2174 bits (121), Expect = 2.863e-6
Identity = 41/195 (21.03%), Postives = 70/195 (35.90%), Query Frame = 2
Query: 1088 ISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPA----DFYPITIP 1660
            +  + D T+ R  GTL      +  C     + L    +++ID C    ++LGPV+ ++   +C+D   V   ++     C++  ++   +T P++  S                                 F  +  FYP L  H     +    N W+    I      +G+  W LLP A    DF P   P
Sbjct:   53 LKELKDVTVGRLPGTLNGEQFVIQECENCNIFVLDHSATITIDDCVNCRIVLGPVKGSVFFRDCKDIKCVVACQQFRTRDCQKMDVFLCCATQPIIESSTGMK-----------------------------FGCFQYFYPELAFHFKDAGLSIFNNNWSN---IHDFTPVSGENNWSLLPEASSVLDFVPTPDP 215          
BLAST of TBCC domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000036233.1 (SMESG000036233.1)

HSP 1 Score: 1145.57 bits (2962), Expect = 0.000e+0
Identity = 597/600 (99.50%), Postives = 597/600 (99.50%), Query Frame = 2
Query:  110 MSTSSSTNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSIDMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTTSVHAGI 1909
            MSTSSSTNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSIDMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSKIQQKKQKIATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPLLSQSLQSNTSSSLLRASNDSLLSASNATTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIG   GPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTTSVHAGI
Sbjct:    1 MSTSSSTNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSIDMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSKIQQKKQKIATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPLLSQSLQSNTSSSLLRASNDSLLSASNATTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIG---GPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTTSVHAGI 597          
BLAST of TBCC domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000036233.1 (SMESG000036233.1)

HSP 1 Score: 1096.65 bits (2835), Expect = 0.000e+0
Identity = 576/600 (96.00%), Postives = 578/600 (96.33%), Query Frame = 2
Query:  110 MSTSSSTNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSIDMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSXXXXXXXXXATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTTSVHAGI 1909
            MSTSSSTNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSIDMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNG ++                  QQKKQKIATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPLLSQSLQSNTSSSLLRASNDSLLSASNATTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIG   GPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTTSVHAGI
Sbjct:    1 MSTSSSTNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKAGYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKLFACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPDTKKSIDMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNKSDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTKTISVKNLLSWIRSNLGSNPFSVEACLTNGSKI------------------QQKKQKIATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLHRCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTRRLVLMGCRRCTIYTVTSTYPLLSQSLQSNTSSSLLRASNDSLLSASNATTQTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIG---GPTGDKIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLRAFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTTSVHAGI 579          
BLAST of TBCC domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000068489.1 (SMESG000068489.1)

HSP 1 Score: 62.7734 bits (151), Expect = 6.806e-10
Identity = 27/27 (100.00%), Postives = 27/27 (100.00%), Query Frame = 2
Query: 1985 IGQNDSQFIGNHNNTNICRNVYQSHCI 2065
            IGQNDSQFIGNHNNTNICRNVYQSHCI
Sbjct:  464 IGQNDSQFIGNHNNTNICRNVYQSHCI 490          
The following BLAST results are available for this feature:
BLAST of TBCC domain-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TBCCD11.684e-10333.73TBCC domain containing 1 [Source:HGNC Symbol;Acc:H... [more]
TBCCD11.684e-10333.73TBCC domain containing 1 [Source:HGNC Symbol;Acc:H... [more]
TBCCD11.443e-7933.33TBCC domain containing 1 [Source:HGNC Symbol;Acc:H... [more]
TBCCD11.638e-2932.88TBCC domain containing 1 [Source:HGNC Symbol;Acc:H... [more]
TBCCD17.938e-1833.57TBCC domain containing 1 [Source:HGNC Symbol;Acc:H... [more]
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BLAST of TBCC domain-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TBCC domain-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TBCC domain-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tbccd11.362e-8430.69TBCC domain containing 1 [Source:NCBI gene;Acc:100... [more]
tbccd14.596e-8430.52TBCC domain containing 1 [Source:NCBI gene;Acc:100... [more]
tbccd14.596e-8430.52TBCC domain containing 1 [Source:NCBI gene;Acc:100... [more]
rp28.360e-620.41RP2 activator of ARL3 GTPase [Source:NCBI gene;Acc... [more]
rp28.360e-620.41RP2 activator of ARL3 GTPase [Source:NCBI gene;Acc... [more]
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BLAST of TBCC domain-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
tbccd14.189e-9129.28TBCC domain containing 1 [Source:NCBI gene;Acc:549... [more]
tbccd11.216e-4330.60TBCC domain containing 1 [Source:NCBI gene;Acc:549... [more]
pdia61.057e-722.45protein disulfide isomerase family A member 6 [Sou... [more]
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BLAST of TBCC domain-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tbccd14.010e-10333.28TBCC domain containing 1 [Source:MGI Symbol;Acc:MG... [more]
Tbccd14.010e-10333.28TBCC domain containing 1 [Source:MGI Symbol;Acc:MG... [more]
Tbccd13.429e-4333.22TBCC domain containing 1 [Source:MGI Symbol;Acc:MG... [more]
Tbccd13.281e-2636.57TBCC domain containing 1 [Source:MGI Symbol;Acc:MG... [more]
Tbccd13.529e-1537.61TBCC domain containing 1 [Source:MGI Symbol;Acc:MG... [more]
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BLAST of TBCC domain-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5FVR8|TBCC1_RAT4.155e-10333.16TBCC domain-containing protein 1 OS=Rattus norvegi... [more]
sp|Q9NVR7|TBCC1_HUMAN8.088e-10333.73TBCC domain-containing protein 1 OS=Homo sapiens O... [more]
sp|Q640P7|TBCC1_MOUSE2.805e-10233.28TBCC domain-containing protein 1 OS=Mus musculus O... [more]
sp|A4IF93|TBCC1_BOVIN8.819e-10133.05TBCC domain-containing protein 1 OS=Bos taurus OX=... [more]
sp|Q08AV6|TBCC1_XENLA1.300e-9430.03TBCC domain-containing protein 1 OS=Xenopus laevis... [more]
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BLAST of TBCC domain-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A504YPK31.360e-16140.72TBCC domain-containing protein 1 OS=Fasciola gigan... [more]
A0A4E0QUN24.631e-16140.86TBCC domain-containing protein 1 OS=Fasciola hepat... [more]
R7TY568.415e-14740.27C-CAP/cofactor C-like domain-containing protein OS... [more]
A0A2T7PE681.763e-14540.90C-CAP/cofactor C-like domain-containing protein OS... [more]
G4VAL03.319e-14341.55C-CAP/cofactor C-like domain-containing protein OS... [more]
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BLAST of TBCC domain-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
tbccd11.820e-10432.44TBCC domain containing 1 [Source:NCBI gene;Acc:103... [more]
rp25.394e-621.43RP2 activator of ARL3 GTPase [Source:NCBI gene;Acc... [more]
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BLAST of TBCC domain-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
TBCCD17.457e-5031.89TBCC domain containing 1 [Source:HGNC Symbol;Acc:H... [more]
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BLAST of TBCC domain-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TBCC domain-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO305259.689e-10133.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO362231.010e-619.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of TBCC domain-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rp21.653e-621.03RP2 activator of ARL3 GTPase [Source:NCBI gene;Acc... [more]
rp22.863e-621.03RP2 activator of ARL3 GTPase [Source:NCBI gene;Acc... [more]
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BLAST of TBCC domain-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000036233.10.000e+099.50SMESG000036233.1[more]
SMESG000036233.10.000e+096.00SMESG000036233.1[more]
SMESG000068489.16.806e-10100.00SMESG000068489.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007577 ID=SMED30007577|Name=TBCC domain-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2321bp
TTCAAATTGGTTGTTAAGTACAATAATATGATATAATTTAAAATTTTTCA
CTTTATCTAATTCAAGTATTATTTTGCAATTATACTCAATTACTTTTTTA
TTTAAAAAAATGTCAACTTCATCTTCGACAAATTTACAGCTATGGGTGAG
GTCTGAGCCATTTACTTATGGTATACTTCACGTAAATCCTCATCCGAGAT
TGCTATCAATGCATAATATCAAAAAATTGGTTAGTTATGCCAAAGTCAAG
GGTAAAGCAGGATATCCTAAATTAAGCTATCCAATATGGAAGCATATTGC
TTGCAACAAATTGCAATTGACAGAAACCTTGACATGGACATTGTTCCATA
CTTGCATTATAATGAGTAACAACAACTCTATCAAGTTGAAAAATTTAGAA
TCGAAATTGTTTGCTTGTGAAAATCCAGAAGAGCAAGAACAAGTCAAAAA
TGGACAATCGATTGAATTATTCCGATTTGTCCTTTATTTATATATCCAAC
AAATCAATAAAATATCTCTTAGAGCTTCAGCTGTTTCACCGAATGCTGAA
TGGCCAGATACAAAAAAATCTATCGACATGGAAGTTTGTAAATCGGCAAA
TAAAAATATGGATGAAATCCAGCATCTTCAATTCGTTTTGTATAATATTG
GAGATATAATAGACATTCTCACGGAGCCAGCTACTTCTGATACTGGAGGC
CCAAATAAATCAGATCCACAAATGGGTCTTAATGCTATCGAAGCCTTAAA
TTTAATTATAGACGGGAGAACTGAGAAAAATGGAAATATCAAACCATTGA
GTGAAATTTTACAAATTGCATCTCAAACCTTGAAAACCGGTTTCTCAAAG
ACGACCAAAACAATAAGTGTAAAAAATTTGCTTTCTTGGATTCGATCAAA
TCTTGGTAGCAATCCGTTTTCAGTTGAAGCATGTCTAACGAATGGTAAAC
GACTATTATGGCCATTGAATAATAATAAAGGCGACGAGCCGATAGTAGGG
AGTAAAATCCAGCAAAAGAAACAAAAAATCGCCACAACAGCAAATTTACT
ACCGAAAGAATTCGGAAAAGGAAACAAACTGATTTTAATTTCATCAATTA
ATGATCAGACAATTGCAAGAAGTTCAGGAACTCTTGAACAAGCATCTTTA
AAGCTTCATCGATGTCATTATAGTTATTTCTACTTCTTGTCTCCATTAAG
AAGTGTCAGTATTGATAAATGTCGAAAATCAACCGTTATTCTGGGACCAG
TAGAAAATACAATACAATTATTTAACTGCGAGGATTGTGTAATTGTCGCA
CCGACACGACGTCTAGTATTAATGGGTTGTCGACGTTGTACCATATATAC
TGTCACAAGCACTTATCCGTTATTATCGCAAAGCCTACAATCTAATACGT
CAAGCTCCTTGTTGCGAGCCAGCAATGATTCACTCTTATCTGCTTCTAAT
GCTACTACGCAAACATTTAATGAAGATATTTGCTTTGCTCCATATTGCTC
ATTCTATCCAACATTAGAAGAACATCTTTCAAAAGTTTCAATTGATCCAA
AAATTAACTTTTGGAATAAACCAATGGTTATAGGAGTTTGCCTAGGACCG
ACTGGAGATAAAATATGGGAGTTATTACCACCAGCTGATTTCTATCCAAT
CACTATTCCATTTGACTTTGAAGGTCCAACAACTAGTTGCCCCACTCCTT
GGCCTTCTGAATATGAAGAAGCATTGAAACAAAGATCCCTGCGATATGAA
AATCTTCGAGCATTTATAAAAAATTCCAAATTGACATCGGAACAAAACAA
ATACTTTCGGAATTTGGTTGAAAAACGATTTCGAAATTGGTTGACAGAAA
GTGATGAATACAGGCAATTGATTCTTTTAGATCCAACGACGAGTGTTCAT
GCGGGTATCAATAACAAAACTTGTAACAATAACCTTAATAGCAGCAATAA
TAATAATAATAATAACAGTAACAATTTAAACTTGATTGGTCAAAATGATT
CTCAATTCATCGGTAACCATAACAACACAAATATTTGTAGAAATGTTTAT
CAATCACATTGTATATAAAAATTTATGATTTTTCCACGGGACCAATAAGC
TTTGTATTTAAATTATTCATGCTTTGATTCGCTGATAAATGATTTCTTTT
TTATAATATTATATAATTTATTATTAGCTCAATATGTGTATGCTTGCTGC
TTTGTACAGAGATTTCTTTGACATTTTTATCTGTTATTATTTCTTGACTT
GAACGGCCTATTATATGGTGATAACAAATCTGATGATGGAAACGATTTTT
ATTATTACTATTATTATTATT
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protein sequence of SMED30007577-orf-1

>SMED30007577-orf-1 ID=SMED30007577-orf-1|Name=SMED30007577-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=653bp
MSTSSSTNLQLWVRSEPFTYGILHVNPHPRLLSMHNIKKLVSYAKVKGKA
GYPKLSYPIWKHIACNKLQLTETLTWTLFHTCIIMSNNNSIKLKNLESKL
FACENPEEQEQVKNGQSIELFRFVLYLYIQQINKISLRASAVSPNAEWPD
TKKSIDMEVCKSANKNMDEIQHLQFVLYNIGDIIDILTEPATSDTGGPNK
SDPQMGLNAIEALNLIIDGRTEKNGNIKPLSEILQIASQTLKTGFSKTTK
TISVKNLLSWIRSNLGSNPFSVEACLTNGKRLLWPLNNNKGDEPIVGSKI
QQKKQKIATTANLLPKEFGKGNKLILISSINDQTIARSSGTLEQASLKLH
RCHYSYFYFLSPLRSVSIDKCRKSTVILGPVENTIQLFNCEDCVIVAPTR
RLVLMGCRRCTIYTVTSTYPLLSQSLQSNTSSSLLRASNDSLLSASNATT
QTFNEDICFAPYCSFYPTLEEHLSKVSIDPKINFWNKPMVIGVCLGPTGD
KIWELLPPADFYPITIPFDFEGPTTSCPTPWPSEYEEALKQRSLRYENLR
AFIKNSKLTSEQNKYFRNLVEKRFRNWLTESDEYRQLILLDPTTSVHAGI
NNKTCNNNLNSSNNNNNNNSNNLNLIGQNDSQFIGNHNNTNICRNVYQSH
CI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000418head
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR039589TBCC1
IPR016098CAP/MinC_C
IPR017901C-CAP_CF_C-like
IPR012945Tubulin-bd_cofactor_C_dom
Vocabulary: biological process
TermDefinition
GO:0000902cell morphogenesis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR016098Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminalGENE3DG3DSA:2.160.20.70coord: 324..521
e-value: 1.7E-26
score: 94.5
IPR012945Tubulin binding cofactor C-like domainPFAMPF07986TBCCcoord: 346..425
e-value: 2.1E-19
score: 69.4
NoneNo IPR availablePANTHERPTHR16052:SF0TBCC DOMAIN-CONTAINING PROTEIN 1coord: 5..593
IPR039589TBCC domain-containing protein 1PANTHERPTHR16052UNCHARACTERIZEDcoord: 5..593
IPR017901C-CAP/cofactor C-like domainPROSITEPS51329C_CAP_COFACTOR_Ccoord: 315..478
score: 26.244