Lysosomal trafficking regulator
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30007567 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 59
Homology
BLAST of Lysosomal trafficking regulator vs. Ensembl Human
Match: LYST (lysosomal trafficking regulator [Source:HGNC Symbol;Acc:HGNC:1968]) HSP 1 Score: 385.956 bits (990), Expect = 2.851e-106 Identity = 297/984 (30.18%), Postives = 482/984 (48.98%), Query Frame = 1
Query: 7444 VFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFA--------ISPDFS-----VEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGE----SLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFH-TMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF--INKSFPAKKINWRNIKNTAPRNI----QHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMT--SKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWD 10317
+ CKE + LG LL+ + + R + + V N ++R CL + L+L + +++ + G TEE + + L+ A I P S ++ + E+ + +E K A++K + + Q D + ++S ++ + ++ N + + I +I+ + W+ LI T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ S + L++LFE DK + E I+++ CI V S GE +GK + F+ED ++ E L L+ F +W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD + I PN + + W G+++NF+YLT LN AGRS+ND+MQYPVFPFIL +Y S TLDL YR+LSKPI++Q ++ ++ + +EY++ R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH T + S S++ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES YVS + W+DLVFG+KQ GKA+++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + S P K+N I+ P + Q +F + E +K ++ + L+ + G++WG++VGSP ++ + + G+L LPT + S+ ++ + V + T+ + + A N R++ P N +Q S Q V S A S ++F G + G+IT Y + + ++ H L GH EI L +C +++L S IWD
Sbjct: 2732 ILWSCKETFRMQLGRLLVHILSPAHAAQERKQIFEIVHE-PNHQEILRDCLSPSLQHGAKLVLYLSELIHN--HQGELTEEELGTAELLMNALKLCGHKCIPPSASTKADLIKMIKEEQKKYETEEGVNK-AAWQKTVNNNQQSLFQRLDSKSKDIS-KIAADITQAVSLSQGNERKKVIQHIRGMYKVDLSASRHWQELIQQLTHDRAVWYDPIYYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LRDRQKSEDVVKPPLSYLFE-----DKTHSSFSSTVKDKAASESIRVNRRCISVAPSRETAGELLLGKCGMYFVEDNASDTV-ESSSLQGELEPASF-SWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKVRDDVYHNILTNNLPNLLEYGNITALTNLWYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLNDLLIYRNLSKPIAVQYKEKEDRYVDTYKYLEEEYRKGAR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKASVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLFHMAHVSRPGAKLN---IEGELPAAVGLLVQFAFRETR----------------EQVKEITYP----SPLSWIKGLKWGEYVGSP-SAPVPVVCFSQPHGERFGSLQALPTRAICGLSRNFCLLMTYSKEQGVRSMNSTDIQWSAILSWGYADNILRLKSKQ---SEPPVNFIQ-----------SSQQYQVTSCAWVPDSCQLFTGSKCGVITAYTNRFTSSTPSEIEMETQIH----LYGHTEEITSLFVCKPYSILISVSRDGTCIIWD 3644 HSP 2 Score: 63.5438 bits (153), Expect = 1.044e-8 Identity = 64/238 (26.89%), Postives = 114/238 (47.90%), Query Frame = 1
Query: 5020 SVDSAIENLGGISIMIFWLAKVVE-SGDEVSTRYXXXXXXXXXRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQHMIYED------PTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQ---EPFEALEHPLPVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHP 5703
++ + +GG I +F A+VVE S E + L++IL LI+ + H+ G S++ Q+ K +GF I+ L++ ED + KL + N+ + +D ++L ELL+ WKI SK E + E LL + L+ D+ + N L ++ L++CQ E E P+P +C+ ++II ++ +P D+ ++T + N +L +HP
Sbjct: 1800 TIQGILHEIGGTGIFVFLFARVVELSSCEETQALALRVILSLIKYNQQRVHELENCNGLSMIHQVLIKQKCIVGFYILKTLLEGCCGEDIIYMNENGEFKLDVDSNA-IIQDVKLLEELLLDWKIW-------SKAEQGVWET--------LLAALEVLIRADHHQQMFNIKQLLKAQVVHHFLLTCQVLQEYKEGQLTPMPREVCRSFVKIIAEVLGSPPDLELLTIIFNFLLAVHP 2021
BLAST of Lysosomal trafficking regulator vs. Ensembl Human
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20751]) HSP 1 Score: 278.1 bits (710), Expect = 5.711e-79 Identity = 156/407 (38.33%), Postives = 233/407 (57.25%), Query Frame = 1
Query: 8470 DIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILP-------------PNAN--RKPRLID-------IQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDK 9621
DI+ V +RR+ L+ A+E+ DGRN L+A + R+++ ++P PN + + L+ + + W G++SNF YL LNT AGRSYND+MQYPVFP+IL +Y S +DLT T+R+L+KP+ Q E+ +Y+++ + + N P YHY + YS++ V Y++R+ PFTQ F++ Q G FD DRMFH++ +W+ ++ +KE+IPEFFYLPE NS +F+ G + NGTK+ DVILP W+ GD R F +HR +LE YVS L+ W+DL+FG+KQ G AA+EA+N+FH Y + I + ++ +A I N+GQIPKQLF K P K++ R + A ++ +SDK
Sbjct: 216 DIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGI-RNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQT-----------DERLAQYKKRYKDWEDPNG-------ETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLF-KKPHPPKRVRSRLNGDNAGISVLPGSTSDK 602
BLAST of Lysosomal trafficking regulator vs. Ensembl Human
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20751]) HSP 1 Score: 279.256 bits (713), Expect = 5.589e-74 Identity = 158/420 (37.62%), Postives = 239/420 (56.90%), Query Frame = 1
Query: 8470 DIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILP-------------PNANRK------PRLI---DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDK-GYQDTDQMKDSI 9657
DI+ V +RR+ L+ A+E+ DGRN L+A + R+++ ++P PN + + L+ + + W G++SNF YL LNT AGRSYND+MQYPVFP+IL +Y S +DLT T+R+L+KP+ Q E+ +Y+++ + + N P YHY + YS++ V Y++R+ PFTQ F++ Q G FD DRMFH++ +W+ ++ +KE+IPEFFYLPE NS +F+ G + NGTK+ DVILP W+ GD R F +HR +LE YVS L+ W+DL+FG+KQ G AA+EA+N+FH Y + I + ++ +A I N+GQIPKQLF K P K++ R + A ++ +SDK + D ++ S+
Sbjct: 2613 DIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGI-RNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQT-----------DERLAQYKKRYKDWEDPNG-------ETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLF-KKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSL 3012
BLAST of Lysosomal trafficking regulator vs. Ensembl Human
Match: NBEA (neurobeachin [Source:HGNC Symbol;Acc:HGNC:7648]) HSP 1 Score: 251.521 bits (641), Expect = 4.464e-69 Identity = 147/375 (39.20%), Postives = 215/375 (57.33%), Query Frame = 1
Query: 8464 LNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILP------PNANR----KPRLI----DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFP 9546
++I V RR+ L++ ALE+ M + + + +++ + + P A R PR + ++ + W ++SNF+YL FLNT AGR+YND+ QYPVFP++LT Y S LDLT +RDLSKPI G L K + E+ + ++ D+ S PPYHY++ YS + + L +++RI PFT F+ DG+FD PDR F ++A SW S S +KE+IPEF+YLPE+FVNS +N G R + V+DV LP W+ F I+R +LES +VS QL+ W+DL+FG+KQ G A+ A+N+FH TY ++ D IT+ + R A+E I+N+GQ P QL I P
Sbjct: 2 FSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPI----GALNPKRAVFYAERYETWE------------DDQS----PPYHYNTHYSTATSTLSWLVRIEPFTTFFLNANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVVVNDVDLPPWAK-KPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPP 355
BLAST of Lysosomal trafficking regulator vs. Ensembl Human
Match: NBEAL1 (neurobeachin like 1 [Source:HGNC Symbol;Acc:HGNC:20681]) HSP 1 Score: 259.225 bits (661), Expect = 5.098e-68 Identity = 159/395 (40.25%), Postives = 225/395 (56.96%), Query Frame = 1
Query: 8374 GFLEDRVNNLYSEYDELPNYLKDFGF-INWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNA---NRKPRLI----DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTK--VDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF 9528
G LE ++Y YD GF W + I + RR+ LR ALE+ D N + + R++I S + ++ PN+ +R P+ + + ++W ++SNFDYL +NT AGR+YND+ QYPVFP+IL +YTS LDL + +RDLSKPI + N EK EK + ++ D M + +HY + YSNSA V++Y+IR+ PFT IQ Q G FD DR FH++ ++W + +KE+IPEFFY PE N FN G RL +K V+DVILP+W+ A F HR +LES YVS L+ W+DL+FG+KQ G AA+EA+N+F+ +Y A+ D +T+E R A+E MI N+GQ P QL
Sbjct: 1905 GRLEITTQHIYF-YDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEV-RNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVN----EKNAKAMREKYENFE------------DPMG--TIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLG-RLQISKELVNDVILPKWAKS-AEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLL 2277
BLAST of Lysosomal trafficking regulator vs. Ensembl Celegans
Match: sel-2 (Putative neurobeachin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q19317]) HSP 1 Score: 274.633 bits (701), Expect = 3.887e-73 Identity = 187/540 (34.63%), Postives = 272/540 (50.37%), Query Frame = 1
Query: 8038 DDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQ-------VDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDEL-PNYLKDFGFI---------NWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNS-------TLERDRILSFIENILPPNANRKPRLI---------DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKI 9558
DDS +Q ++LD E SR R+R + + + N +N + + S E + + + + ++V E+ ID K +++ + C S K G G L N+L+ + +E PNY K + W+L +I + RR+ L++ ALE+ + + A +S + R+ ++ LP +RK L+ D+ +W + ++SNFDYL FLNT AGR++ND+ QYPVFP+ILT YTS TLDL+ S +RDLSKPI G L E F D Y TS + D+ VP +HY + YS A L +++R+ PF FI DG+FD PDR+ H++ SW +KE+IPE FYLPE+F NS FN G R +GT VDDV+LP W+ F L+HR +LES VS QLN W+DL+FG+KQ G A+ A N+F+ TY + P + +A+EQ I ++GQ P QL P I
Sbjct: 1598 DDSKSGTQFWKLDVWEDDSRRRKRFVPNAYGSRHEEANLPEGEKNEEPEISEQEKIRKVLKGLFSKRQNSSGSHELVDESDID----KWAQEVDPTPSSQSACFSTTAK-LIAPGVVVPGTLSVTANDLFFDANESDPNYKKQCAQVLRYCEALHARWNLQEIRAIFLRRYLLQNTALELFLASRTAIMFAFDSEDAVKKVVYQLPRVGVGVKYGLP--QSRKTSLMTPRQLFKHSDMCAKWQKREISNFDYLMFLNTVAGRTFNDLSQYPVFPWILTNYTSDTLDLSVASNFRDLSKPI----GALSEARRKFFN---DRY--------TSWDDDQ-----VPAFHYGTHYSTPAFTLNWLLRVEPFASMFINLHDGKFDHPDRITHSIKDSWDRCQRDSHDVKELIPELFYLPEMFRNSSKFNLGRRADGTPVDDVVLPPWAESPEH-FVLMHRQALESDLVSCQLNQWIDLIFGYKQRGAEAVRATNVFYHLTYEGTVTPKMAETPGQVAAIEQQILSFGQTPSQLLTEAHPPRHSI 2109
BLAST of Lysosomal trafficking regulator vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2]) HSP 1 Score: 270.781 bits (691), Expect = 8.017e-72 Identity = 150/392 (38.27%), Postives = 215/392 (54.85%), Query Frame = 1
Query: 8467 NDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFI-------------------ENILPPNANRKPRLID-------IQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKIN 9561
N I V +RR+ L+ ALE+ DGRN L+A + RDR+ + N+ R L+ + + W G +SNF YL LNT AGR YND+ QYP+FP++L +YTSS LD ST+RD SKP+ Q+ E+ + F E D PPY Y + YS++ V+ Y++R+ PFTQ+F+ Q G FD DRMFH++ +W ++ + +KE+IPEFF LPE+F N+ F+ G + NG V+DV+LP W GD R F +HR +LES YVS+ L+ W+DL+FG+KQ G+ A++ NLFH Y ++ + I + + R+A + N+GQIP QLF K P KK+N
Sbjct: 2501 NMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKI-RDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGE------------------TPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLF-KKPHPQKKVN 2872
BLAST of Lysosomal trafficking regulator vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2]) HSP 1 Score: 270.781 bits (691), Expect = 8.499e-72 Identity = 150/392 (38.27%), Postives = 215/392 (54.85%), Query Frame = 1
Query: 8467 NDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFI-------------------ENILPPNANRKPRLID-------IQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKIN 9561
N I V +RR+ L+ ALE+ DGRN L+A + RDR+ + N+ R L+ + + W G +SNF YL LNT AGR YND+ QYP+FP++L +YTSS LD ST+RD SKP+ Q+ E+ + F E D PPY Y + YS++ V+ Y++R+ PFTQ+F+ Q G FD DRMFH++ +W ++ + +KE+IPEFF LPE+F N+ F+ G + NG V+DV+LP W GD R F +HR +LES YVS+ L+ W+DL+FG+KQ G+ A++ NLFH Y ++ + I + + R+A + N+GQIP QLF K P KK+N
Sbjct: 2499 NMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKI-RDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGE------------------TPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLF-KKPHPQKKVN 2870
BLAST of Lysosomal trafficking regulator vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2]) HSP 1 Score: 270.781 bits (691), Expect = 8.506e-72 Identity = 150/392 (38.27%), Postives = 215/392 (54.85%), Query Frame = 1
Query: 8467 NDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFI-------------------ENILPPNANRKPRLID-------IQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKIN 9561
N I V +RR+ L+ ALE+ DGRN L+A + RDR+ + N+ R L+ + + W G +SNF YL LNT AGR YND+ QYP+FP++L +YTSS LD ST+RD SKP+ Q+ E+ + F E D PPY Y + YS++ V+ Y++R+ PFTQ+F+ Q G FD DRMFH++ +W ++ + +KE+IPEFF LPE+F N+ F+ G + NG V+DV+LP W GD R F +HR +LES YVS+ L+ W+DL+FG+KQ G+ A++ NLFH Y ++ + I + + R+A + N+GQIP QLF K P KK+N
Sbjct: 2503 NMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKI-RDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGE------------------TPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLF-KKPHPQKKVN 2874
BLAST of Lysosomal trafficking regulator vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2]) HSP 1 Score: 270.781 bits (691), Expect = 8.574e-72 Identity = 150/392 (38.27%), Postives = 215/392 (54.85%), Query Frame = 1
Query: 8467 NDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFI-------------------ENILPPNANRKPRLID-------IQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKIN 9561
N I V +RR+ L+ ALE+ DGRN L+A + RDR+ + N+ R L+ + + W G +SNF YL LNT AGR YND+ QYP+FP++L +YTSS LD ST+RD SKP+ Q+ E+ + F E D PPY Y + YS++ V+ Y++R+ PFTQ+F+ Q G FD DRMFH++ +W ++ + +KE+IPEFF LPE+F N+ F+ G + NG V+DV+LP W GD R F +HR +LES YVS+ L+ W+DL+FG+KQ G+ A++ NLFH Y ++ + I + + R+A + N+GQIP QLF K P KK+N
Sbjct: 2501 NMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKI-RDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGE------------------TPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLF-KKPHPQKKVN 2872
BLAST of Lysosomal trafficking regulator vs. Ensembl Fly
Match: mv (gene:FBgn0265988 transcript:FBtr0304060) HSP 1 Score: 300.827 bits (769), Expect = 7.825e-81 Identity = 180/538 (33.46%), Postives = 285/538 (52.97%), Query Frame = 1
Query: 7978 YRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYF-NPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISC--------PCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILS--FIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKK 9555
Y W +I T E W + + + LD EGPSR+ R+ + I+ ++F N P + ++ D Y P+D + + + IS + G +GE + ++ FL Y + +N + +I + +R++ ++ A E+++ ++ ++ + + +I+ F + I+ K +I I ++W EG ++N++YL LN +GR+YND+MQYPVFP++L Y S LDL + +R L +PI++Q E Y + ++N M + PYHYSS YSNS TVL++++R+PPFT F+++QD +FD PDR FH + ++W L++ +KE+IPEFF LPE+F N + F FG R NG +V+DV LP WS D+RLF LIHR +LES V NQ++ W+DL+FG+KQ+G++A+EAIN+FHP T Y EI++ I R AV+ M++ YGQ+P+QLF PA K
Sbjct: 2595 YTYTKWLEIIRRMTHEGAPWHSAERAECSWELDDTEGPSRVHTRLRRCHLDIDRRFFMNEYRPGQG------------------HREDLEPYVRPLDYLIASYDQQLNISLNSQILYNFAAKFLPVDGEIEGEIIITDLKLYFLA--------------TYRCRYFNVNCDIANITEIWLKRYQHQETAFEILLDTNKSLFFSLQNA-DDWKIMREVFCDKIVATPDQSK--VIAITQQWREGLLTNWEYLMTLNQISGRTYNDLMQYPVFPWVLANYNSEVLDLREGHNFRRLGRPIAVQ-----------VEENEKHYISNYTYIDSTNTT--MGSLILKPYHYSSHYSNSGTVLHFLVRVPPFTSYFLRYQDNDFDLPDRTFHALNTTWLLASRDSPTDVKELIPEFFCLPEMFENFERFKFGCRQNGERVEDVSLPPWSQRDSRLFVLIHRQALESELVRNQIHNWIDLIFGYKQSGESAVEAINVFHPAT-YAVFLDSEISDPIEREAVKTMVKTYGQMPRQLF-KSPHPASK 3082
BLAST of Lysosomal trafficking regulator vs. Ensembl Fly
Match: CG43367 (gene:FBgn0263110 transcript:FBtr0307309) HSP 1 Score: 270.396 bits (690), Expect = 1.115e-71 Identity = 203/619 (32.79%), Postives = 295/619 (47.66%), Query Frame = 1
Query: 7765 NLWVKENEFKLNAYKK-KFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYAR---KNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYEN----------------PIDCQLLK--CIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPN----ANRKP----RLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGE-RLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF 9528
+LW N F Y+ K SK NQ +RR + I M R LQH+ I + + R WK + W + ++L E +R+R ++ Y N A N++D ++S + E + V + ID Q + +E + +S C L+ KG V + F++ L ++ Y DF F N I V R++ LR ALE+ + D + + +T R+++ + I + PN + R P R + + W ++SNF+YL +LNT AGRSYND+ QYPVFP+IL +YTS LDLT ++RDLSKPI N P E + K D + E A+P +HY + YSNSA VL+Y++R+ PFT I Q G FD DR FH++ +W L + + +KE+IPEFFY PE N F+ G ++ KVDDVILP W++ F IHR +LES YVS L++W+DL+FG+KQ G A EA+N+F+ +Y A+ D+IT + R AVE MI N+GQ+P QL
Sbjct: 1771 HLWEPINRFWAECYEACKAASKQRATNQAENRRLFQQKIYMPWKVRQVEEMQRLQAAALQHKTIDS---------HIRKRWKTAKRFLYGPRGPWYTGEVDEEFWKLSQHENVARMRLKLEPQL------YPNKHENAANLRDNATSAYDTKEISEFDSTIKNAVVRDFLADDESSQLEEELRQLIDTQAQQDVALEKLVMSQDCELITLMTKVKGRIEVNQSVFTFVD-----LSPPTEDGSKY--DFRFST---NKIREVHLRKYNLRRSALEIFLVDQTSYFLNF-TTKTRNKVFTKIVGLPLPNILYGSGRSPAELLRASGLTQRWINREISNFEYLMYLNTIAGRSYNDLSQYPVFPWILADYTSDVLDLTDPKSFRDLSKPIGCIN-PKNEAEVR---GKYDSF--------------EDPSGAIPKFHYGTHYSNSAGVLHYLLRVEPFTSLHIDLQSGRFDVADRQFHSIPQTWKLLMDNPNDVKELIPEFFYFPEFLKNMNKFDLGHLQITKEKVDDVILPAWATTPEE-FIAIHRRALESEYVSQHLHHWIDLIFGYKQKGPKAAEALNVFYYCSYEGAVDLDKITNPVEREAVEGMINNFGQVPSQLL 2344
BLAST of Lysosomal trafficking regulator vs. Ensembl Fly
Match: CG43367 (gene:FBgn0263110 transcript:FBtr0307310) HSP 1 Score: 270.011 bits (689), Expect = 1.335e-71 Identity = 203/619 (32.79%), Postives = 295/619 (47.66%), Query Frame = 1
Query: 7765 NLWVKENEFKLNAYKK-KFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYAR---KNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYEN----------------PIDCQLLK--CIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPN----ANRKP----RLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGE-RLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF 9528
+LW N F Y+ K SK NQ +RR + I M R LQH+ I + + R WK + W + ++L E +R+R ++ Y N A N++D ++S + E + V + ID Q + +E + +S C L+ KG V + F++ L ++ Y DF F N I V R++ LR ALE+ + D + + +T R+++ + I + PN + R P R + + W ++SNF+YL +LNT AGRSYND+ QYPVFP+IL +YTS LDLT ++RDLSKPI N P E + K D + E A+P +HY + YSNSA VL+Y++R+ PFT I Q G FD DR FH++ +W L + + +KE+IPEFFY PE N F+ G ++ KVDDVILP W++ F IHR +LES YVS L++W+DL+FG+KQ G A EA+N+F+ +Y A+ D+IT + R AVE MI N+GQ+P QL
Sbjct: 1729 HLWEPINRFWAECYEACKAASKQRATNQAENRRLFQQKIYMPWKVRQVEEMQRLQAAALQHKTIDS---------HIRKRWKTAKRFLYGPRGPWYTGEVDEEFWKLSQHENVARMRLKLEPQL------YPNKHENAANLRDNATSAYDTKEISEFDSTIKNAVVRDFLADDESSQLEEELRQLIDTQAQQDVALEKLVMSQDCELITLMTKVKGRIEVNQSVFTFVD-----LSPPTEDGSKY--DFRFST---NKIREVHLRKYNLRRSALEIFLVDQTSYFLNF-TTKTRNKVFTKIVGLPLPNILYGSGRSPAELLRASGLTQRWINREISNFEYLMYLNTIAGRSYNDLSQYPVFPWILADYTSDVLDLTDPKSFRDLSKPIGCIN-PKNEAEVR---GKYDSF--------------EDPSGAIPKFHYGTHYSNSAGVLHYLLRVEPFTSLHIDLQSGRFDVADRQFHSIPQTWKLLMDNPNDVKELIPEFFYFPEFLKNMNKFDLGHLQITKEKVDDVILPAWATTPEE-FIAIHRRALESEYVSQHLHHWIDLIFGYKQKGPKAAEALNVFYYCSYEGAVDLDKITNPVEREAVEGMINNFGQVPSQLL 2302
BLAST of Lysosomal trafficking regulator vs. Ensembl Fly
Match: CG43367 (gene:FBgn0263110 transcript:FBtr0307312) HSP 1 Score: 270.011 bits (689), Expect = 1.385e-71 Identity = 203/619 (32.79%), Postives = 295/619 (47.66%), Query Frame = 1
Query: 7765 NLWVKENEFKLNAYKK-KFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYAR---KNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYEN----------------PIDCQLLK--CIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPN----ANRKP----RLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGE-RLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF 9528
+LW N F Y+ K SK NQ +RR + I M R LQH+ I + + R WK + W + ++L E +R+R ++ Y N A N++D ++S + E + V + ID Q + +E + +S C L+ KG V + F++ L ++ Y DF F N I V R++ LR ALE+ + D + + +T R+++ + I + PN + R P R + + W ++SNF+YL +LNT AGRSYND+ QYPVFP+IL +YTS LDLT ++RDLSKPI N P E + K D + E A+P +HY + YSNSA VL+Y++R+ PFT I Q G FD DR FH++ +W L + + +KE+IPEFFY PE N F+ G ++ KVDDVILP W++ F IHR +LES YVS L++W+DL+FG+KQ G A EA+N+F+ +Y A+ D+IT + R AVE MI N+GQ+P QL
Sbjct: 1571 HLWEPINRFWAECYEACKAASKQRATNQAENRRLFQQKIYMPWKVRQVEEMQRLQAAALQHKTIDS---------HIRKRWKTAKRFLYGPRGPWYTGEVDEEFWKLSQHENVARMRLKLEPQL------YPNKHENAANLRDNATSAYDTKEISEFDSTIKNAVVRDFLADDESSQLEEELRQLIDTQAQQDVALEKLVMSQDCELITLMTKVKGRIEVNQSVFTFVD-----LSPPTEDGSKY--DFRFST---NKIREVHLRKYNLRRSALEIFLVDQTSYFLNF-TTKTRNKVFTKIVGLPLPNILYGSGRSPAELLRASGLTQRWINREISNFEYLMYLNTIAGRSYNDLSQYPVFPWILADYTSDVLDLTDPKSFRDLSKPIGCIN-PKNEAEVR---GKYDSF--------------EDPSGAIPKFHYGTHYSNSAGVLHYLLRVEPFTSLHIDLQSGRFDVADRQFHSIPQTWKLLMDNPNDVKELIPEFFYFPEFLKNMNKFDLGHLQITKEKVDDVILPAWATTPEE-FIAIHRRALESEYVSQHLHHWIDLIFGYKQKGPKAAEALNVFYYCSYEGAVDLDKITNPVEREAVEGMINNFGQVPSQLL 2144
BLAST of Lysosomal trafficking regulator vs. Ensembl Fly
Match: CG43367 (gene:FBgn0263110 transcript:FBtr0307311) HSP 1 Score: 270.011 bits (689), Expect = 1.385e-71 Identity = 203/619 (32.79%), Postives = 295/619 (47.66%), Query Frame = 1
Query: 7765 NLWVKENEFKLNAYKK-KFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYAR---KNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYEN----------------PIDCQLLK--CIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPN----ANRKP----RLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGE-RLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF 9528
+LW N F Y+ K SK NQ +RR + I M R LQH+ I + + R WK + W + ++L E +R+R ++ Y N A N++D ++S + E + V + ID Q + +E + +S C L+ KG V + F++ L ++ Y DF F N I V R++ LR ALE+ + D + + +T R+++ + I + PN + R P R + + W ++SNF+YL +LNT AGRSYND+ QYPVFP+IL +YTS LDLT ++RDLSKPI N P E + K D + E A+P +HY + YSNSA VL+Y++R+ PFT I Q G FD DR FH++ +W L + + +KE+IPEFFY PE N F+ G ++ KVDDVILP W++ F IHR +LES YVS L++W+DL+FG+KQ G A EA+N+F+ +Y A+ D+IT + R AVE MI N+GQ+P QL
Sbjct: 1571 HLWEPINRFWAECYEACKAASKQRATNQAENRRLFQQKIYMPWKVRQVEEMQRLQAAALQHKTIDS---------HIRKRWKTAKRFLYGPRGPWYTGEVDEEFWKLSQHENVARMRLKLEPQL------YPNKHENAANLRDNATSAYDTKEISEFDSTIKNAVVRDFLADDESSQLEEELRQLIDTQAQQDVALEKLVMSQDCELITLMTKVKGRIEVNQSVFTFVD-----LSPPTEDGSKY--DFRFST---NKIREVHLRKYNLRRSALEIFLVDQTSYFLNF-TTKTRNKVFTKIVGLPLPNILYGSGRSPAELLRASGLTQRWINREISNFEYLMYLNTIAGRSYNDLSQYPVFPWILADYTSDVLDLTDPKSFRDLSKPIGCIN-PKNEAEVR---GKYDSF--------------EDPSGAIPKFHYGTHYSNSAGVLHYLLRVEPFTSLHIDLQSGRFDVADRQFHSIPQTWKLLMDNPNDVKELIPEFFYFPEFLKNMNKFDLGHLQITKEKVDDVILPAWATTPEE-FIAIHRRALESEYVSQHLHHWIDLIFGYKQKGPKAAEALNVFYYCSYEGAVDLDKITNPVEREAVEGMINNFGQVPSQLL 2144
BLAST of Lysosomal trafficking regulator vs. Ensembl Zebrafish
Match: lyst (lysosomal trafficking regulator [Source:ZFIN;Acc:ZDB-GENE-070702-1]) HSP 1 Score: 376.711 bits (966), Expect = 7.456e-104 Identity = 253/797 (31.74%), Postives = 413/797 (51.82%), Query Frame = 1
Query: 7444 VFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEE-----FIKSLS---------------QLLFAISPD-FSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFES-TYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPN 9765
+ C++ + +G +L+ +L L R EA++ V N+ ++R L L L + ++L K + ++ E+ F+ +L LL AI + E ++ W K KL+ ++ +LD +++ + +++ + R ++++ + +++ A R W+ L+ T ++ +W D + ++LDP EGP+R RRR+ + I +KY R + D S L FLFE T+ IV + E I+ + C+ V S GE +GK + F+E+ V + ++ P+ + +W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD + I PN + + W+ G+++NF+YLT LN AGRS+ND+MQYPVFPFIL +YT+ TLDL + S YR+LSKPI++Q+ ++ ++ + +EY++ R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R N +V+ V LP W+ D RLF LIHR +LES VS L W+DLVFG KQ GKAA++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QL F A I+ K + + + G ++S E +D + L + G++WG++VGSP+
Sbjct: 1592 ILWSCRDTFRVQIGRMLVHTLSPELPLEDRKEALEFVHE-QNYSEILRESLSPGLEHGPKLALYLYELLHDHKDALSREEQAAGNTFMTALKLCGHRCIPPSAPAKPDLLKAIKEEQLKYESEARTSKGAWEK----KLSNTQRSLLQRLDGKSKDISKIAADITQNVSLRQGMERKKVMQHIRGLYKTDLSASR--------HWQELVQQLTHDRAVWYDQSSYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--LKDRRKLDD--SIKAPLAFLFEDKTHSSSSIVKDKATS-------EPIRFTRRCVSVAPSRETAGELLLGKSGMYFVEENVPETHD--NQSPHGETEPASFSWTYEEIKEVHKRWWQLRDNAMEIFLTNGRTLLLAFDNTKFRDDVYHNILTSDLPNLLEYGNISALTHLWSSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILKDYTNETLDLQEASIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGKR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRLPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNSERVNHVNLPPWARNDPRLFILIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQL-----FSASHISRAGTKLLS----EAELPAAMGLLVQLAFRESREQ--------PRDSGYPSPLPWIKGLKWGEYVGSPS 2336
BLAST of Lysosomal trafficking regulator vs. Ensembl Zebrafish
Match: lyst (lysosomal trafficking regulator [Source:ZFIN;Acc:ZDB-GENE-070702-1]) HSP 1 Score: 374.4 bits (960), Expect = 3.309e-103 Identity = 252/797 (31.62%), Postives = 413/797 (51.82%), Query Frame = 1
Query: 7444 VFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEE-----FIKSLS---------------QLLFAISPD-FSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFES-TYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPN 9765
+ C++ + +G +L+ +L L R EA++ V ++ ++R L L L + ++L K + ++ E+ F+ +L LL AI + E ++ W K KL+ ++ +LD +++ + +++ + R ++++ + +++ A R W+ L+ T ++ +W D + ++LDP EGP+R RRR+ + I +KY R + D S L FLFE T+ IV + E I+ + C+ V S GE +GK + F+E+ V + ++ P+ + +W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD + I PN + + W+ G+++NF+YLT LN AGRS+ND+MQYPVFPFIL +YT+ TLDL + S YR+LSKPI++Q+ ++ ++ + +EY++ R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R N +V+ V LP W+ D RLF LIHR +LES VS L W+DLVFG KQ GKAA++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QL F A I+ K + + + G ++S E +D + L + G++WG++VGSP+
Sbjct: 1598 ILWSCRDTFRVQIGRMLVHTLSPELPLEDRKEALEFVHE-QSYSEILRESLSPGLEHGPKLALYLYELLHDHKDALSREEQAAGNTFMTALKLCGHRCIPPSAPAKPDLLKAIKEEQLKYESEARTSKGAWEK----KLSNTQRSLLQRLDGKSKDISKIAADITQNVSLRQGMERKKVMQHIRGLYKTDLSASR--------HWQELVQQLTHDRAVWYDQSSYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--LKDRRKLDD--SIKAPLAFLFEDKTHSSSSIVKDKATS-------EPIRFTRRCVSVAPSRETAGELLLGKSGMYFVEENVPETHD--NQSPHGETEPASFSWTYEEIKEVHKRWWQLRDNAMEIFLTNGRTLLLAFDNTKFRDDVYHNILTSDLPNLLEYGNISALTHLWSSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILKDYTNETLDLQEASIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGKR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRLPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNSERVNHVNLPPWARNDPRLFILIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQL-----FSASHISRAGTKLLS----EAELPAAMGLLVQLAFRESREQ--------PRDSGYPSPLPWIKGLKWGEYVGSPS 2342
BLAST of Lysosomal trafficking regulator vs. Ensembl Zebrafish
Match: wdfy4 (WDFY family member 4 [Source:ZFIN;Acc:ZDB-GENE-090313-322]) HSP 1 Score: 266.929 bits (681), Expect = 4.426e-75 Identity = 144/382 (37.70%), Postives = 221/382 (57.85%), Query Frame = 1
Query: 8458 WHLNDIEWVLRRRFKLRDYALEMIMKDG-----------------RNCLIAMNSTLERDRILS-------FIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF 9528
W +DI+ RF L D ALE+ +K+G R C + + + +L+ F++ +A K LI +W G++SNF+YL LNT AGR+YND+MQYP+FP+++ +Y S TLDL+ +T+RDLSKP+ Q +EK I R ++ NN ++S HY + YS++ V Y++R+ PF+Q F+Q Q G FD P+RMFH++ + W ++ ++E+IPEFFYLP+ VNS F+FG +GT ++DV+LP W+ GD + F +HR +LES YVS++L+ W+DL+FG++Q G A+EA+N FHPY Y + + + +S + I N+GQ+PKQ+F
Sbjct: 13 WSYDDIKEANFMRFLLEDNALEIFLKNGTSVFLVFFNNDHVNAYKRLCSVVSSLKGRGETVLNVSRSGLLFVKTRRKTSAVEKTVLI----KWQRGEISNFEYLMHLNTLAGRTYNDLMQYPIFPWVIADYESETLDLSSPATFRDLSKPMGAQTEKRKEKFIQ-------------RYLEVENNDGDLSAQC----HYCTHYSSAIIVASYLVRMEPFSQTFLQLQGGTFDVPERMFHSIQNEWESASKDNMSDVRELIPEFFYLPDFLVNSNQFDFGCMQDGTPLNDVVLPPWAKGDPQEFIRVHREALESDYVSSRLHLWIDLIFGYRQQGMPAVEALNTFHPYFYTDKHDRASMKDPVMKSTMLGYINNFGQMPKQIF 373
BLAST of Lysosomal trafficking regulator vs. Ensembl Zebrafish
Match: wdfy3 (WD repeat and FYVE domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-070705-153]) HSP 1 Score: 272.322 bits (695), Expect = 5.033e-72 Identity = 149/386 (38.60%), Postives = 221/386 (57.25%), Query Frame = 1
Query: 8470 DIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNAN-------RKPR------------LI---DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKI 9558
DI V +RR+ L+ A E+ DGRN L+A + R+++ ++P A+ ++P L+ + + W G++SNF YL LNT AGRSYND+MQYPVFP+IL ++ S LDL T+R+LSKP+ Q ++ +Y+++ + + N P YHY + YS++ V Y++R+ PFTQ F++ Q G FD DRMFH++ +W ++ +KE+IPEFFYLPE +NS +F+ G + NGTK+ DVILP W+ GD R F +HR +LE YVS L+ W+DL+FG+KQ G A+EA+N+FH Y + I + ++ +A I N+GQIPKQLF K P K++
Sbjct: 2598 DIREVHKRRYLLQPMAAEVFSGDGRNYLLAFQKGV-RNKVYQRFLAVVPSLADSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLNNPKTFRNLSKPMGAQT-----------DDRLIQYKKRFKDWEDPNG-------ETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWLSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGSKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPPAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLF-KKPHPPKRV 2963
BLAST of Lysosomal trafficking regulator vs. Ensembl Zebrafish
Match: nbeal1 (neurobeachin-like 1 [Source:ZFIN;Acc:ZDB-GENE-130530-544]) HSP 1 Score: 262.307 bits (669), Expect = 3.739e-69 Identity = 179/533 (33.58%), Postives = 275/533 (51.59%), Query Frame = 1
Query: 7993 WKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVD---------KIVYENPI-----DCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRI--LSFIENILPPNANRKPRLI----DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGE-RLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF 9528
W+ E+ W D K ++L E SR+R ++++ + + + VQ + + ESL L E+ QV +++ E+P D + E + IS C LV + G + I F + S ++ +DF W L+ I + RR+ LR ALE+ + D N + + R+ + + L +A P+ + + ++W ++SNFDYL LNT AGR+YND+ QYPVFP+IL++YTS LDL+ +RDLSKP+++QN E+ EK + ++ + ID +HY + YSN+A V++Y+IR+ PFT IQ Q G FD DR FH++ ++W + + +KE+IPEFFY PE N F+ G +++ +V+DVILP+W+ F HR +LES +VS L+ W+DL+FG+KQ G AA+EA+N+F+ TY A+ D IT+E R AVE MI N+GQ P QL
Sbjct: 1360 WRAARRGLFCERGPWVDKQLKDIHWKLSSAENYSRMRLKLVRNYNFDTHREASALRDNLGVQHQQVNAESL--LLEAVKQVKVSDLEDDILELLEEDPASANQADSEEAGQKEKLVISEDCELVTVVDVYPGRLELTTQHIYFYD-------SSAEKEEGVGQDF---KWPLSQIREIHLRRYNLRRSALEIFLIDQTNYFLNFKKEV-RNTVYSRMLLLRSLSLHATHSPQELLKSSGLTQKWVNREISNFDYLMQLNTIAGRTYNDLAQYPVFPWILSDYTSEELDLSDPRVFRDLSKPVAVQN----ERNAKAVREKYESFE------DPTGTIDR--------FHYGTHYSNAAGVMHYLIRVEPFTSLHIQLQSGRFDCADRQFHSIPATWQTLMDNPNDVKELIPEFFYFPEFLENQNGFDLGRLQISKERVNDVILPKWAKSPED-FIYKHRKALESEFVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCTYEGAVDLDAITDEKERKAVEGMISNFGQTPCQLL 1860
BLAST of Lysosomal trafficking regulator vs. Ensembl Xenopus
Match: LYST (lysosomal trafficking regulator [Source:NCBI gene;Acc:779601]) HSP 1 Score: 350.517 bits (898), Expect = 1.253e-95 Identity = 245/794 (30.86%), Postives = 402/794 (50.63%), Query Frame = 1
Query: 7441 SVFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFAIS------------PDFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGES----LTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF--INKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPN 9765
++ CK+ + LG LL+ L L +R +A+ V + ++R CL L L + +++ K + E+ L ++ PD ++ ++E+ + +ENE ++ A++K + Q D R ++S + + ++ + + I +I++ + W+ L+ T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ E+ L++LFE DK + E I+++ CI V S GE + + W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD I I N PN + + W G+++NF+YLT LN AGRS++D+MQYPVFPFIL++Y + TLDL+ + YR+L+KPI++Q+ ++ I+ + DEY + R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES VS + +W+DLVFG+KQ G+AA++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + S P K+ ++ + G +DS + S+D + L + G++WG++VGSP+
Sbjct: 2634 TILWSCKDTFRVQLGRLLVHLLSPSQPLEVRKQALDIV-QEPKHQEILRDCLSPGLQHGPKLALYLYELMHDHKEELTKEEQVAGGLFMNALKLTGYRCIPPSAPPKPDL-IKAISEEQKKYENEENENRV-AWRKTIINNQQKLFQRLDARSKDLS-KTAGDITQSVSLSQGMERKKVIQHIRSMYKVDLSASRHWQELVQQLTHDRAVWYDPESYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LRDRQKPEETVKPPLSYLFE-----DKTHSSFSSTVKDKAASERIRVTQRCINVAPSRETFGELLL---------------------------EAASFAWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKIRDDIYHNILNNNLPNLLEYGNITALTHLWCTGQITNFEYLTHLNKHAGRSFSDLMQYPVFPFILSDYFNETLDLSDSAIYRNLAKPIAVQSKEKEDRYIDNYKYLEDEYCKGDR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMKTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGLRQNGERVNHVNLPPWARNDPRLFILIHRQALESDNVSQTICHWIDLVFGYKQKGRAAVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLFHSAHVSRPGSKL-----------LMEGELPAAMGLLVQLAFRDS--------RDTSRDVGHPSPLPWIKGLKWGEYVGSPS 3355
BLAST of Lysosomal trafficking regulator vs. Ensembl Xenopus
Match: LYST (lysosomal trafficking regulator [Source:NCBI gene;Acc:779601]) HSP 1 Score: 350.517 bits (898), Expect = 1.326e-95 Identity = 245/794 (30.86%), Postives = 402/794 (50.63%), Query Frame = 1
Query: 7441 SVFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFAIS------------PDFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGES----LTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF--INKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPN 9765
++ CK+ + LG LL+ L L +R +A+ V + ++R CL L L + +++ K + E+ L ++ PD ++ ++E+ + +ENE ++ A++K + Q D R ++S + + ++ + + I +I++ + W+ L+ T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ E+ L++LFE DK + E I+++ CI V S GE + + W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD I I N PN + + W G+++NF+YLT LN AGRS++D+MQYPVFPFIL++Y + TLDL+ + YR+L+KPI++Q+ ++ I+ + DEY + R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES VS + +W+DLVFG+KQ G+AA++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + S P K+ ++ + G +DS + S+D + L + G++WG++VGSP+
Sbjct: 2587 TILWSCKDTFRVQLGRLLVHLLSPSQPLEVRKQALDIV-QEPKHQEILRDCLSPGLQHGPKLALYLYELMHDHKEELTKEEQVAGGLFMNALKLTGYRCIPPSAPPKPDL-IKAISEEQKKYENEENENRV-AWRKTIINNQQKLFQRLDARSKDLS-KTAGDITQSVSLSQGMERKKVIQHIRSMYKVDLSASRHWQELVQQLTHDRAVWYDPESYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LRDRQKPEETVKPPLSYLFE-----DKTHSSFSSTVKDKAASERIRVTQRCINVAPSRETFGELLL---------------------------EAASFAWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKIRDDIYHNILNNNLPNLLEYGNITALTHLWCTGQITNFEYLTHLNKHAGRSFSDLMQYPVFPFILSDYFNETLDLSDSAIYRNLAKPIAVQSKEKEDRYIDNYKYLEDEYCKGDR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMKTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGLRQNGERVNHVNLPPWARNDPRLFILIHRQALESDNVSQTICHWIDLVFGYKQKGRAAVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLFHSAHVSRPGSKL-----------LMEGELPAAMGLLVQLAFRDS--------RDTSRDVGHPSPLPWIKGLKWGEYVGSPS 3308
BLAST of Lysosomal trafficking regulator vs. Ensembl Xenopus
Match: LYST (lysosomal trafficking regulator [Source:NCBI gene;Acc:779601]) HSP 1 Score: 350.517 bits (898), Expect = 1.362e-95 Identity = 245/794 (30.86%), Postives = 402/794 (50.63%), Query Frame = 1
Query: 7441 SVFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFAIS------------PDFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGES----LTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF--INKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPN 9765
++ CK+ + LG LL+ L L +R +A+ V + ++R CL L L + +++ K + E+ L ++ PD ++ ++E+ + +ENE ++ A++K + Q D R ++S + + ++ + + I +I++ + W+ L+ T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ E+ L++LFE DK + E I+++ CI V S GE + + W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD I I N PN + + W G+++NF+YLT LN AGRS++D+MQYPVFPFIL++Y + TLDL+ + YR+L+KPI++Q+ ++ I+ + DEY + R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES VS + +W+DLVFG+KQ G+AA++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + S P K+ ++ + G +DS + S+D + L + G++WG++VGSP+
Sbjct: 2632 TILWSCKDTFRVQLGRLLVHLLSPSQPLEVRKQALDIV-QEPKHQEILRDCLSPGLQHGPKLALYLYELMHDHKEELTKEEQVAGGLFMNALKLTGYRCIPPSAPPKPDL-IKAISEEQKKYENEENENRV-AWRKTIINNQQKLFQRLDARSKDLS-KTAGDITQSVSLSQGMERKKVIQHIRSMYKVDLSASRHWQELVQQLTHDRAVWYDPESYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LRDRQKPEETVKPPLSYLFE-----DKTHSSFSSTVKDKAASERIRVTQRCINVAPSRETFGELLL---------------------------EAASFAWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKIRDDIYHNILNNNLPNLLEYGNITALTHLWCTGQITNFEYLTHLNKHAGRSFSDLMQYPVFPFILSDYFNETLDLSDSAIYRNLAKPIAVQSKEKEDRYIDNYKYLEDEYCKGDR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMKTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGLRQNGERVNHVNLPPWARNDPRLFILIHRQALESDNVSQTICHWIDLVFGYKQKGRAAVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLFHSAHVSRPGSKL-----------LMEGELPAAMGLLVQLAFRDS--------RDTSRDVGHPSPLPWIKGLKWGEYVGSPS 3353
BLAST of Lysosomal trafficking regulator vs. Ensembl Xenopus
Match: LYST (lysosomal trafficking regulator [Source:NCBI gene;Acc:779601]) HSP 1 Score: 350.517 bits (898), Expect = 1.455e-95 Identity = 245/794 (30.86%), Postives = 402/794 (50.63%), Query Frame = 1
Query: 7441 SVFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFAIS------------PDFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGES----LTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF--INKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPN 9765
++ CK+ + LG LL+ L L +R +A+ V + ++R CL L L + +++ K + E+ L ++ PD ++ ++E+ + +ENE ++ A++K + Q D R ++S + + ++ + + I +I++ + W+ L+ T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ E+ L++LFE DK + E I+++ CI V S GE + + W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD I I N PN + + W G+++NF+YLT LN AGRS++D+MQYPVFPFIL++Y + TLDL+ + YR+L+KPI++Q+ ++ I+ + DEY + R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES VS + +W+DLVFG+KQ G+AA++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + S P K+ ++ + G +DS + S+D + L + G++WG++VGSP+
Sbjct: 2626 TILWSCKDTFRVQLGRLLVHLLSPSQPLEVRKQALDIV-QEPKHQEILRDCLSPGLQHGPKLALYLYELMHDHKEELTKEEQVAGGLFMNALKLTGYRCIPPSAPPKPDL-IKAISEEQKKYENEENENRV-AWRKTIINNQQKLFQRLDARSKDLS-KTAGDITQSVSLSQGMERKKVIQHIRSMYKVDLSASRHWQELVQQLTHDRAVWYDPESYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LRDRQKPEETVKPPLSYLFE-----DKTHSSFSSTVKDKAASERIRVTQRCINVAPSRETFGELLL---------------------------EAASFAWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKIRDDIYHNILNNNLPNLLEYGNITALTHLWCTGQITNFEYLTHLNKHAGRSFSDLMQYPVFPFILSDYFNETLDLSDSAIYRNLAKPIAVQSKEKEDRYIDNYKYLEDEYCKGDR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMKTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGLRQNGERVNHVNLPPWARNDPRLFILIHRQALESDNVSQTICHWIDLVFGYKQKGRAAVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLFHSAHVSRPGSKL-----------LMEGELPAAMGLLVQLAFRDS--------RDTSRDVGHPSPLPWIKGLKWGEYVGSPS 3347
BLAST of Lysosomal trafficking regulator vs. Ensembl Xenopus
Match: LYST (lysosomal trafficking regulator [Source:NCBI gene;Acc:779601]) HSP 1 Score: 350.517 bits (898), Expect = 1.501e-95 Identity = 245/794 (30.86%), Postives = 402/794 (50.63%), Query Frame = 1
Query: 7441 SVFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFAIS------------PDFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGES----LTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF--INKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPN 9765
++ CK+ + LG LL+ L L +R +A+ V + ++R CL L L + +++ K + E+ L ++ PD ++ ++E+ + +ENE ++ A++K + Q D R ++S + + ++ + + I +I++ + W+ L+ T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ E+ L++LFE DK + E I+++ CI V S GE + + W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD I I N PN + + W G+++NF+YLT LN AGRS++D+MQYPVFPFIL++Y + TLDL+ + YR+L+KPI++Q+ ++ I+ + DEY + R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES VS + +W+DLVFG+KQ G+AA++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + S P K+ ++ + G +DS + S+D + L + G++WG++VGSP+
Sbjct: 2615 TILWSCKDTFRVQLGRLLVHLLSPSQPLEVRKQALDIV-QEPKHQEILRDCLSPGLQHGPKLALYLYELMHDHKEELTKEEQVAGGLFMNALKLTGYRCIPPSAPPKPDL-IKAISEEQKKYENEENENRV-AWRKTIINNQQKLFQRLDARSKDLS-KTAGDITQSVSLSQGMERKKVIQHIRSMYKVDLSASRHWQELVQQLTHDRAVWYDPESYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LRDRQKPEETVKPPLSYLFE-----DKTHSSFSSTVKDKAASERIRVTQRCINVAPSRETFGELLL---------------------------EAASFAWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKIRDDIYHNILNNNLPNLLEYGNITALTHLWCTGQITNFEYLTHLNKHAGRSFSDLMQYPVFPFILSDYFNETLDLSDSAIYRNLAKPIAVQSKEKEDRYIDNYKYLEDEYCKGDR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMKTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGLRQNGERVNHVNLPPWARNDPRLFILIHRQALESDNVSQTICHWIDLVFGYKQKGRAAVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLFHSAHVSRPGSKL-----------LMEGELPAAMGLLVQLAFRDS--------RDTSRDVGHPSPLPWIKGLKWGEYVGSPS 3336
BLAST of Lysosomal trafficking regulator vs. Ensembl Mouse
Match: Lyst (lysosomal trafficking regulator [Source:MGI Symbol;Acc:MGI:107448]) HSP 1 Score: 379.407 bits (973), Expect = 2.020e-104 Identity = 258/808 (31.93%), Postives = 413/808 (51.11%), Query Frame = 1
Query: 7936 EFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSG----ESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFH-TMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF--INKSFPAKKINWRNIKNTAPRNI----QHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMTSKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXI---AVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWD 10317
+ I +I+ + W+ I T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ S L++LFE DK + E I+++ CI V S GE +GK + F+ED ++ E L L+ F +W +I+ V RR ++LRD A+E+ + +GR L+A ++ RD + I PN + + W G+++NF+YLT LN AGRS+ND+MQYPVFPFIL++Y S TLDL S YR+LSKPI++Q ++ ++ + +EY++ R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH T + S S++ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES +VS + +W+DLVFG+KQ GKA+++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + S P K+N I+ P + Q +F + E +K ++ + L+ + G++WG++VGSP ++ + + G+L LPT + + +LM E+G + + N +Q ++ ++N ++L++ S + A S ++F G + G+IT Y + + + +++ H L GH EI L +C ++V+ S +WD
Sbjct: 2890 KVIQHIRGMYKVDLSASRHWQECIQQLTHDRAVWYDPIYYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LRDRQKSEGVLRPPLSYLFE-----DKTHSSFSSTVKDKAASESIRVNRRCISVAPSRETAGELLLGKCGMYFVEDNASDAV-ESSSLQGELEPASF-SWTYEEIKEVHRRWWQLRDNAVEIFLTNGRTLLLAFDNNKVRDDVYQSILTNNLPNLLEYGNITALTNLWYSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILSDYVSETLDLNDPSIYRNLSKPIAVQYKEKEDRYVDTYKYLEEEYRKGAR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDHVSQNICHWIDLVFGYKQKGKASVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLFHTAHASRPGAKLN---IEGELPAAVGLLVQFAFRETR----------------EPVKEVTHP----SPLSWIKGLKWGEYVGSP-SAPVPVVCFSQPHGERFGSLQALPTRAICG--------LSRNFCLLMTYNKEQGVR-------SMNNTNIQWSAILSWGYADNILRLKSKQSEPPINFIQSSQQHQVTSCAWVPDSCQLFTGSKCGVITAYTNRLTSSTPSEIEMESQMH----LYGHTEEITGLCVCKPYSVMISVSRDGTCIVWD 3630
BLAST of Lysosomal trafficking regulator vs. Ensembl Mouse
Match: Wdfy3 (WD repeat and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:1096875]) HSP 1 Score: 277.715 bits (709), Expect = 1.074e-73 Identity = 157/420 (37.38%), Postives = 239/420 (56.90%), Query Frame = 1
Query: 8470 DIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILP-------------PNAN--RKPRLID-------IQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDK-GYQDTDQMKDSI 9657
DI+ V +RR+ L+ A+E+ DGRN L+A + R+++ ++P PN + + L+ + + W G++SNF YL LNT AGRSYND+MQYPVFP+IL++Y S +DLT T+R+L+KP+ Q E+ +Y+++ + + N P YHY + YS++ V Y++R+ PFTQ F++ Q G FD DRMFH++ +W+ ++ +KE+IPEFFYLPE NS +F+ G + NGTK+ DVILP W+ GD R F +HR +LE YVS L+ W+DL+FG+KQ G AA+EA+N+FH Y + I + ++ +A I N+GQIPKQLF K P K++ R + ++ +SDK + D ++ S+
Sbjct: 2595 DIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGI-RNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQT-----------DERLAQYKKRYKDWEDPNG-------ETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLF-KKPHPPKRVRSRLNGDNIGISVPPGATSDKIFFHHLDNLRPSL 2994
BLAST of Lysosomal trafficking regulator vs. Ensembl Mouse
Match: Wdfy3 (WD repeat and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:1096875]) HSP 1 Score: 277.715 bits (709), Expect = 1.133e-73 Identity = 157/420 (37.38%), Postives = 239/420 (56.90%), Query Frame = 1
Query: 8470 DIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILP-------------PNANRK------PRLI---DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDK-GYQDTDQMKDSI 9657
DI+ V +RR+ L+ A+E+ DGRN L+A + R+++ ++P PN + + L+ + + W G++SNF YL LNT AGRSYND+MQYPVFP+IL++Y S +DLT T+R+L+KP+ Q E+ +Y+++ + + N P YHY + YS++ V Y++R+ PFTQ F++ Q G FD DRMFH++ +W+ ++ +KE+IPEFFYLPE NS +F+ G + NGTK+ DVILP W+ GD R F +HR +LE YVS L+ W+DL+FG+KQ G AA+EA+N+FH Y + I + ++ +A I N+GQIPKQLF K P K++ R + ++ +SDK + D ++ S+
Sbjct: 2613 DIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGI-RNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQT-----------DERLAQYKKRYKDWEDPNG-------ETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLF-KKPHPPKRVRSRLNGDNIGISVPPGATSDKIFFHHLDNLRPSL 3012
BLAST of Lysosomal trafficking regulator vs. Ensembl Mouse
Match: Wdfy3 (WD repeat and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:1096875]) HSP 1 Score: 277.715 bits (709), Expect = 1.199e-73 Identity = 157/420 (37.38%), Postives = 239/420 (56.90%), Query Frame = 1
Query: 8470 DIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILP-------------PNAN--RKPRLID-------IQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDK-GYQDTDQMKDSI 9657
DI+ V +RR+ L+ A+E+ DGRN L+A + R+++ ++P PN + + L+ + + W G++SNF YL LNT AGRSYND+MQYPVFP+IL++Y S +DLT T+R+L+KP+ Q E+ +Y+++ + + N P YHY + YS++ V Y++R+ PFTQ F++ Q G FD DRMFH++ +W+ ++ +KE+IPEFFYLPE NS +F+ G + NGTK+ DVILP W+ GD R F +HR +LE YVS L+ W+DL+FG+KQ G AA+EA+N+FH Y + I + ++ +A I N+GQIPKQLF K P K++ R + ++ +SDK + D ++ S+
Sbjct: 2599 DIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGI-RNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQT-----------DERLAQYKKRYKDWEDPNG-------ETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLF-KKPHPPKRVRSRLNGDNIGISVPPGATSDKIFFHHLDNLRPSL 2998
BLAST of Lysosomal trafficking regulator vs. Ensembl Mouse
Match: Wdfy4 (WD repeat and FYVE domain containing 4 [Source:MGI Symbol;Acc:MGI:3584510]) HSP 1 Score: 268.085 bits (684), Expect = 8.007e-71 Identity = 192/620 (30.97%), Postives = 303/620 (48.87%), Query Frame = 1
Query: 7900 NYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYR--LDPIEGPSRIRRRM--IKTTHKINDKYFNPTSPARNV-------QDKSSSGES-------------LTF---LFESTYQVD--KIVYENPIDCQLLKCIEDIQISCPCILVCESGHF--KGEFFVGKWRIGFLED----RVNNLYSEYDELPNYLKDFGF-------------INWHL-NDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILP----------PNANRKPRLID---IQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRN 9570
NYR ++ + ++ +++ +W + E +W + ++ R LD EGP+R+R+R+ + +N Y +V QD+ ++ E+ LTF L ES + D ++ E + Q L E + P ++V GH +G G+ E+ ++Y + L N F F H +D+ + + RF L+D ALE+ ++G + L+ ++ +R + L P P RK D +QR W + ++SNF+YL +LNT AGR+YND MQYPVFP++L +YTS L+LT T+RDLSKP+ Q +R+L+ Q +++++ HY + YS++ V Y++R+PPFTQ F Q G FD DRMFH++ S+W ++ ++E+ PEFFYLPE N FG +GT + DV LP W+ GD R F +HR +LES +VS+ L++W+DL+FG+KQ G AA+EA+N FHPY Y I IT+ + +S + I N+GQ+PKQ+F K P++ +N
Sbjct: 2069 NYRRKGQELYASIYKDYVQRRKSGSIKAATAWARMREQLFGELGLWGQMTESTRCSRWELDGREGPARMRKRIRHLLAWEPLNLGYKESQEGKGDVSQTNTGNQDELTTEEAESRPDEVGVDCTQLTFFPALHESLHSEDFLELCRERQVILQELLDGEKVSQKVPMVIV--QGHLVSEGILLFGQHHFYICENFTLSPTGDVYCTHHCLSNISDPFIFNMCSKDRSSDHYSCQRHAYSDLRELRQARFLLQDIALEIFFQNGYSKLLVFYNS-DRSKALKSFSTFQPSLKGKGTTEDPFNLRKHPGFDRTMLQR-WQKREISNFEYLMYLNTLAGRTYNDYMQYPVFPWVLADYTSEMLNLTNPKTFRDLSKPMGAQT-----------------KERKLKFTQRFKDVEKIEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCSLQGGSFDVADRMFHSVKSTWESASKENMSDVRELTPEFFYLPEFLTNCNAVEFGCMQDGTTLGDVQLPPWADGDPRKFISLHRQALESDFVSSNLHHWIDLIFGYKQQGPAAVEAVNTFHPYFYGDRIDLGSITDPLIKSTILGFISNFGQVPKQIF-TKPHPSRNTTGKN 2666
BLAST of Lysosomal trafficking regulator vs. UniProt/SwissProt
Match: sp|Q99698|LYST_HUMAN (Lysosomal-trafficking regulator OS=Homo sapiens OX=9606 GN=LYST PE=1 SV=3) HSP 1 Score: 385.956 bits (990), Expect = 1.369e-105 Identity = 297/984 (30.18%), Postives = 482/984 (48.98%), Query Frame = 1
Query: 7444 VFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFA--------ISPDFS-----VEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGE----SLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFH-TMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF--INKSFPAKKINWRNIKNTAPRNI----QHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMT--SKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWD 10317
+ CKE + LG LL+ + + R + + V N ++R CL + L+L + +++ + G TEE + + L+ A I P S ++ + E+ + +E K A++K + + Q D + ++S ++ + ++ N + + I +I+ + W+ LI T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ S + L++LFE DK + E I+++ CI V S GE +GK + F+ED ++ E L L+ F +W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD + I PN + + W G+++NF+YLT LN AGRS+ND+MQYPVFPFIL +Y S TLDL YR+LSKPI++Q ++ ++ + +EY++ R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH T + S S++ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES YVS + W+DLVFG+KQ GKA+++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + S P K+N I+ P + Q +F + E +K ++ + L+ + G++WG++VGSP ++ + + G+L LPT + S+ ++ + V + T+ + + A N R++ P N +Q S Q V S A S ++F G + G+IT Y + + ++ H L GH EI L +C +++L S IWD
Sbjct: 2732 ILWSCKETFRMQLGRLLVHILSPAHAAQERKQIFEIVHE-PNHQEILRDCLSPSLQHGAKLVLYLSELIHN--HQGELTEEELGTAELLMNALKLCGHKCIPPSASTKADLIKMIKEEQKKYETEEGVNK-AAWQKTVNNNQQSLFQRLDSKSKDIS-KIAADITQAVSLSQGNERKKVIQHIRGMYKVDLSASRHWQELIQQLTHDRAVWYDPIYYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LRDRQKSEDVVKPPLSYLFE-----DKTHSSFSSTVKDKAASESIRVNRRCISVAPSRETAGELLLGKCGMYFVEDNASDTV-ESSSLQGELEPASF-SWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKVRDDVYHNILTNNLPNLLEYGNITALTNLWYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLNDLLIYRNLSKPIAVQYKEKEDRYVDTYKYLEEEYRKGAR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKASVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLFHMAHVSRPGAKLN---IEGELPAAVGLLVQFAFRETR----------------EQVKEITYP----SPLSWIKGLKWGEYVGSP-SAPVPVVCFSQPHGERFGSLQALPTRAICGLSRNFCLLMTYSKEQGVRSMNSTDIQWSAILSWGYADNILRLKSKQ---SEPPVNFIQ-----------SSQQYQVTSCAWVPDSCQLFTGSKCGVITAYTNRFTSSTPSEIEMETQIH----LYGHTEEITSLFVCKPYSILISVSRDGTCIIWD 3644 HSP 2 Score: 63.5438 bits (153), Expect = 5.012e-8 Identity = 64/238 (26.89%), Postives = 114/238 (47.90%), Query Frame = 1
Query: 5020 SVDSAIENLGGISIMIFWLAKVVE-SGDEVSTRYXXXXXXXXXRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQHMIYED------PTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQ---EPFEALEHPLPVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHP 5703
++ + +GG I +F A+VVE S E + L++IL LI+ + H+ G S++ Q+ K +GF I+ L++ ED + KL + N+ + +D ++L ELL+ WKI SK E + E LL + L+ D+ + N L ++ L++CQ E E P+P +C+ ++II ++ +P D+ ++T + N +L +HP
Sbjct: 1800 TIQGILHEIGGTGIFVFLFARVVELSSCEETQALALRVILSLIKYNQQRVHELENCNGLSMIHQVLIKQKCIVGFYILKTLLEGCCGEDIIYMNENGEFKLDVDSNA-IIQDVKLLEELLLDWKIW-------SKAEQGVWET--------LLAALEVLIRADHHQQMFNIKQLLKAQVVHHFLLTCQVLQEYKEGQLTPMPREVCRSFVKIIAEVLGSPPDLELLTIIFNFLLAVHP 2021
BLAST of Lysosomal trafficking regulator vs. UniProt/SwissProt
Match: sp|Q9TTK4|LYST_BOVIN (Lysosomal-trafficking regulator OS=Bos taurus OX=9913 GN=LYST PE=1 SV=1) HSP 1 Score: 383.645 bits (984), Expect = 6.475e-105 Identity = 297/984 (30.18%), Postives = 483/984 (49.09%), Query Frame = 1
Query: 7444 VFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFA--------ISPDFSVED-----LNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGE----SLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFH-TMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF--INKSFPAKKINWRNIKNTAPRNI----QHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMT--SKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWD 10317
+ CKE + LG LL+ + R + + V R N ++R CL + L+L + +++ + K TEE + + L+ A I P S + + E+ R +E K N ++K + + Q D + ++S ++ + ++ + + I +I+ + W+ LI T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ S + L++LFE DK + E I+++ CI V S GE +GK + F+ED ++ E L L+ F +W +I+ V +R ++LRD A+E+ + +GR L+A ++T R+ + I PN + + W G+++NF+YLT LN AGRS+ND+MQYPVFPFIL +Y S TLDL+ S YR+LSKPI++Q ++ ++ + +EY++ R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH T + S S++ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES YVS + W+DLVFG+KQ GKA+++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + S P K+N I+ P + Q +F + E +K ++ + L+ + G++WG++VGSP ++ + + G+L LPT + S+ ++ + V + T+ + + A N R++ P N +Q S Q V S A S ++F G + G+IT Y + + +++ H L GH EI L +C ++++ S IWD
Sbjct: 2727 ILWSCKETFRMQLGRLLVHMLSPAHPSQERKQIFEIV-REPNHQEILRECLSPSLQHGAKLVLYLSELIHNHK--DELTEEELDTAELLMNALKLCGHKCIPPSASTKSDLIRVIKEEQRKYETEEGVNKAN-WQKTVNNNQQSLFQRLDSKSKDIS-KIAADITQAVSLSQGIERKKVIQHIRGMYKVDLSASRHWQELIQQLTHDRAVWYDPIYYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LRDRQKSEDVVKPPLSYLFE-----DKTHSSFSSTVKDKAASESIRVNRRCISVAPSRETAGELLLGKCGMYFVEDNASDTV-ECSNLQGELEPASF-SWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKVRNDVYHSILTNNLPNLLEYGNITALTHLWYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLSDPSVYRNLSKPIAVQYKEKEDRYVDTYKYLEEEYRKGAR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKASVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLFQSAHASRPGSKLN---IEGELPAAVGLLVQFAFRETR----------------EQVKEITYP----SPLSWIKGLKWGEYVGSP-SAPVPVVCFSQPHGERFGSLQALPTRAICGLSRNFCLLMTYSKEQGVRSMNSTDIQWSAILSWGYADNILRLKSKQ---SEPPINFIQ-----------SSQQYQVTSCAWVPDSCQLFTGSKCGVITAYSNRFTSGTPSEIEMESQIH----LYGHTEEISSLFVCKPYSIMISVSRDGTCIIWD 3639 HSP 2 Score: 56.225 bits (134), Expect = 9.263e-6 Identity = 61/241 (25.31%), Postives = 109/241 (45.23%), Query Frame = 1
Query: 5020 SVDSAIENLGGISIMIFWLAKVVESGDEVSTRYXXXXXXXXXRKSVFLAHQNIEE----KGYSVLLQLFKSFKMTLGFDIISDLVQHMIYED------PTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQEPFEALEHPL---PVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHP 5703
++ + +GG I +F A+VVE T+ L ++L + K Q I E G S++ Q+ K +GF I+ L++ ED + KL + N+ + +D ++L ELL+ WKI +K E + E LL + L+ D+ + N L ++ L++CQ E E L P +C+ ++I ++ +P D+ ++T + N +L +HP
Sbjct: 1795 TLQGILHEIGGTGIFVFLFARVVELSSCEETQALALRVILSLIK---YNQQRIHELENCNGLSMIHQVLIKQKCIVGFHILKTLLEGCCGEDIIHINENGELKLDVESNA-IIQDVKLLEELLLDWKIW-------NKAEHGVWET--------LLAALEVLIRADHQQQMFNIKQLLKARVVHHFLLTCQVLQEHKEGQLISMPQEVCRSFVKITAEVLGSPPDLELLTIIFNFLLAVHP 2016
BLAST of Lysosomal trafficking regulator vs. UniProt/SwissProt
Match: sp|P97412|LYST_MOUSE (Lysosomal-trafficking regulator OS=Mus musculus OX=10090 GN=Lyst PE=1 SV=1) HSP 1 Score: 379.407 bits (973), Expect = 1.474e-103 Identity = 258/808 (31.93%), Postives = 413/808 (51.11%), Query Frame = 1
Query: 7936 EFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSG----ESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFH-TMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF--INKSFPAKKINWRNIKNTAPRNI----QHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMTSKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXI---AVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWD 10317
+ I +I+ + W+ I T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ S L++LFE DK + E I+++ CI V S GE +GK + F+ED ++ E L L+ F +W +I+ V RR ++LRD A+E+ + +GR L+A ++ RD + I PN + + W G+++NF+YLT LN AGRS+ND+MQYPVFPFIL++Y S TLDL S YR+LSKPI++Q ++ ++ + +EY++ R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH T + S S++ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES +VS + +W+DLVFG+KQ GKA+++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + S P K+N I+ P + Q +F + E +K ++ + L+ + G++WG++VGSP ++ + + G+L LPT + + +LM E+G + + N +Q ++ ++N ++L++ S + A S ++F G + G+IT Y + + + +++ H L GH EI L +C ++V+ S +WD
Sbjct: 2891 KVIQHIRGMYKVDLSASRHWQECIQQLTHDRAVWYDPIYYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LRDRQKSEGVLRPPLSYLFE-----DKTHSSFSSTVKDKAASESIRVNRRCISVAPSRETAGELLLGKCGMYFVEDNASDAV-ESSSLQGELEPASF-SWTYEEIKEVHRRWWQLRDNAVEIFLTNGRTLLLAFDNNKVRDDVYQSILTNNLPNLLEYGNITALTNLWYSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILSDYVSETLDLNDPSIYRNLSKPIAVQYKEKEDRYVDTYKYLEEEYRKGAR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDHVSQNICHWIDLVFGYKQKGKASVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLFHTAHASRPGAKLN---IEGELPAAVGLLVQFAFRETR----------------EPVKEVTHP----SPLSWIKGLKWGEYVGSP-SAPVPVVCFSQPHGERFGSLQALPTRAICG--------LSRNFCLLMTYNKEQGVR-------SMNNTNIQWSAILSWGYADNILRLKSKQSEPPINFIQSSQQHQVTSCAWVPDSCQLFTGSKCGVITAYTNRLTSSTPSEIEMESQMH----LYGHTEEITGLCVCKPYSVMISVSRDGTCIVWD 3631
BLAST of Lysosomal trafficking regulator vs. UniProt/SwissProt
Match: sp|Q86JF2|LVSB_DICDI (BEACH domain-containing protein lvsB OS=Dictyostelium discoideum OX=44689 GN=lvsB PE=4 SV=1) HSP 1 Score: 286.189 bits (731), Expect = 2.152e-75 Identity = 161/382 (42.15%), Postives = 223/382 (58.38%), Query Frame = 1
Query: 8452 INWHLNDIEWVLRRRFKLRDYALEMIMKDG---RNCLIAMNSTLERDRILSFIENILPPN-------ANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINW 9564
I W +DI + +RR L++ A+E+ + G + L A N +RD + I + PN + + I ++W G +SNF+YL LNT AGRS+ND+ QYP+FPFIL +Y S LDL +T+RD +KP+ Q+ EK I ++Y L M + PYHY S YSN +VL++++R+ PFT FI FQ G FD PDR FH++A SW+LS+S + +KE+IPEFFYL + VNS F G + NG KVDDVILP W+ D RLF H +LE YVS L++W+DL+FG+KQ G+AA++A N+F P TY A+ D I +++ R A I +YGQ PKQ+F P K NW
Sbjct: 3426 ITWSYDDIIEIHKRRHVLKNNAIEIFLGSGVPHKTYLFAFNKPSDRDIVYDLIMSKPLPNRVDYAAEVHGNILKMSITKKWQSGLISNFEYLMHLNTLAGRSFNDLTQYPIFPFILRDYESEVLDLENPNTFRDFTKPMGAQDPKRLEKFI-------EKYNDLLEMNE-------------KPYHYGSHYSNIGSVLHFLVRLQPFTSYFIDFQGGRFDVPDRAFHSIAQSWNLSSSISNSDVKELIPEFFYLSDFLVNSNKFFMGIKQNGVKVDDVILPPWAHNDPRLFIKKHNEALECKYVSENLHHWIDLLFGYKQQGEAAVKAHNMFFPLTYEGAVDIDSIEDQLNRDAAVAQIHSYGQTPKQIFTK---PHPKKNW 3784
BLAST of Lysosomal trafficking regulator vs. UniProt/SwissProt
Match: sp|Q55DM1|LVSA_DICDI (BEACH domain-containing protein lvsA OS=Dictyostelium discoideum OX=44689 GN=lvsA PE=4 SV=2) HSP 1 Score: 284.648 bits (727), Expect = 7.625e-75 Identity = 170/461 (36.88%), Postives = 247/461 (53.58%), Query Frame = 1
Query: 8284 IEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLY-SEYDELPNYLKDFG-FINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRIL-SFIENILPPNA----------------------------NRKPRLIDIQRE------WAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXX-XXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAK 9552
IE I I CP + G++K E I +E+++N+ + E LP K F+ W DI VL+RR+ LR ALE+ DGRN L+ RD + + + N+ N + R I R+ W +G++SNF YL LNT AGRSYND+ QYPVFP++L++Y S LD+ YRDLSKP+ G L E F E+ + + Q VP +HY + YS++A VLYY+IR+ PFTQ F++ Q G +D+PDR+F ++ + S S + E+IPEF+YL E VN+ FNFG + G +DD+ILP W+ G + F +HR +LES YVS L+ W+DL+FG++Q GKAA +++N+F+ TY A+ D I++ + ++A I N+GQ PKQLF +K P +
Sbjct: 2827 IEGILIFCPVYMYIFDGYYKDE---NTGDISEVEEKINSEWLPEGTVLPMKKKIIHYFLKWAYEDIRDVLKRRYLLRQVALEIFSTDGRNNLVVYRDEPTRDEVYHTLVNNVSSHNTIGGDAQGITGGQTGNDDNDDHHGGGGGRGVRDRFTSIWRKSPLTLKWQQGQISNFQYLMHLNTLAGRSYNDLTQYPVFPWVLSDYESEELDIDDPKVYRDLSKPM----GALEESRAQKFRERFENWDDQEPNEHGHK---------VPKFHYGTHYSSAAIVLYYLIRLEPFTQHFLKLQGGRWDQPDRLFSSITEAWASSSQGSTGVVMELIPEFYYLDEFLVNNNKFNFGTKQGGEPIDDIILPPWAKGSPQEFIKLHRKALESDYVSEHLHEWIDLIFGYRQQGKAADDSLNVFYYLTYEGAVNIDAISDPVEKAATIAQINNFGQTPKQLF-DKPHPKR 3270
BLAST of Lysosomal trafficking regulator vs. TrEMBL
Match: A0A4Z2H9X9 (Lysosomal-trafficking regulator OS=Liparis tanakae OX=230148 GN=LYST_0 PE=4 SV=1) HSP 1 Score: 427.172 bits (1097), Expect = 7.047e-123 Identity = 311/1019 (30.52%), Postives = 496/1019 (48.68%), Query Frame = 1
Query: 7801 AYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHE-FISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYD-----ELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMT--SKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQXXXXXXXXXXXXIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQYISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESG 10830
A++KK + N Q D + ++S + N R+ ++ + I +I+ ++ W+ L+ T ++ +W D ++LDP EGP+R RRR+ + I +KY R +D ++ L+FL E DK + E I+ + CI V S GE +GK + F+ED + + E P++ +W +I+ V +R ++LRD A+E+ + +GR LIA ++T RD + I PN + + + W G++SNF+YLT LN AGRS+ND+MQYPVFPFIL +YTS T+DL S YR+L KPI++Q ++ ++ + +EY++ +R D M V PYHY S YSNS TVL++M+R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES VS L W+DLVFG KQ GKAA+ AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + ++ P+ ++ + G +++ E +K+ C + L + G++WG++VGSP+ + G+L LPT + S++ M++ + V + T+ + + A N R++ P N +Q L V S A ++F G + G+IT Y + F + + V++ H L GH E+ L +C +++L S +WD L L Y+ Q + + V+A+S SET GD+ +V S++ L+T+NG + + + S++++ EG +VN IA + G + + S+W+L+ V +V + S PI ++ Y+ G LY N G
Sbjct: 63 AWEKKMTNTQRNLLQRLDGKSKDISKIAADITQN--VSLRQGMERKKVIQHIRGLYKTDLSASRHWQELVQQLTHDRAVWYDQTSYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--LKDRRKAED--AAKPPLSFLVE-----DKTHSSFSSTVKDKATSEPIRFTRRCISVVPSRETAGELLLGKSGMFFVEDNAADAHDNQSLHGETEAPSF-------SWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLIAFDNTKFRDDVYHNILTSDLPNLLEHGNITALTQLWGLGQISNFEYLTHLNKHAGRSFNDLMQYPVFPFILRDYTSETIDLQDISIYRNLIKPIAVQTKEKEDRYVDNYRYLEEEYKKGIR------EDDPMP--PVQPYHYGSHYSNSGTVLHFMVRMPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFDFGIRQNGERVNHVNLPPWARNDPRLFILIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAVHAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLF----------SASHVSRAGPKLMEGELPAAMGLLVQLAFRETREQ--------AKEIVCPSPLPWIKGLKWGEYVGSPSAPDPV-VCFSQPHGERFGSLLALPTRAICGLSRKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYADNILRLKSKQ---SEPPINFIQCSQL-----------HQVTSCAWVPDGCQLFTGSKCGVITAY-SNRFTSTTSDMEVESKVH----LYGHTGEVTSLFVCKPYSILISVSQDGTCILWD---LNRLCYV-------------------------------QSLTGHKSPVTAVSASETTGDIATV----CDSVGGG--SDLRLWTVNGDLIGHVHCREIICSVAFSNQPEGVSVNVIAGGLENGVVRLWSTWDLKPVREVTFSK--SSKPIISLTYSCDGHHLYTANSEG 974
BLAST of Lysosomal trafficking regulator vs. TrEMBL
Match: A0A3B3U614 (Lysosomal trafficking regulator OS=Poecilia latipinna OX=48699 PE=4 SV=1) HSP 1 Score: 441.039 bits (1133), Expect = 6.847e-120 Identity = 333/1160 (28.71%), Postives = 550/1160 (47.41%), Query Frame = 1
Query: 7444 VFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEH----VKRSGNQTEEFIKSLSQLLFAISP-------DFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGES----LTFLFE-------STYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEY-----DELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMT--SKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQXXXXXXXXXXXXIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQ-YISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESG 10830
+ CK+ + +G LL+ L L R EA++ VF + D + G G + + + +H K + F+ SL + P D ++ + ED +E K A++KK + N Q D + ++S + N + + + + I +I+ ++ W+ L+ T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ E+ L+FLFE S+ DK E+ I+ + C V S GE +GK + F+ED + + E P++ +W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD + I PN ++ + + W+ G+++NF+YLT LN AGRS+ND+MQYPVFPFIL++Y S T+DL + YR+L+KPI++Q+ ++ ++ + +EY++ +R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES +VS L W+DLVFG KQ GKAA+ AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + +I TAP+ + + M ++ + +K+ C + L + G++WG++VGSP+ + G+L LPT + S+ M++ + V + T+ + + A N R++ P N +Q L V S A ++F G + G+IT Y + + V++ H L GH E+ L +C +++L S +WD L L Y+ Q + + V+A+S SET GD+ NS+ S++ L+T+NG + + T+ S++++ EG +VN IA + G + + S+W+L+ V ++ P+ S PI ++ Y+ G LY N G
Sbjct: 2483 ILWSCKDTFRVQIGRLLVHTLSPSLPLQDRKEALEFVFDHKHIDILKESLSPGLEHGPKLSLYLFEMLHDHKDELTKEEQSAVGVFMTSLKLCGYRCIPLNVPHKHDL-LKAIKEDKMKFEAEEKTSK-AAWEKKMANTQKNLIQRLDGKSKDISKIAADITQNV-SLKQGMERKKVIQHIRGLYKTDLSASRHWQELVQQLTHDRAVWYDQTSYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LKDRRKPEETVKPPLSFLFEDKTHSFFSSTVKDKATSES------------IRFTRRCTSVAPSRETAGELLLGKSGMHFVEDNAADAHDSQILQGETEAPSF-------SWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKFRDDVYHNILTSDLPNLLEHGNILALTQLWSSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILSDYVSETIDLQDANIYRNLNKPIAVQSKEKEDRYVDNYRYLEEEYKKGIR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESEHVSQTLCQWIDLVFGLKQKGKAAVHAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLF----------SATHISRTAPKLMMEG-------ELPAAMGLLVQLAFRETREHAKEIVCPSPLPWIKGLKWGEYVGSPSAPDPV-VCFSQPHGERFGSLLALPTRAICGLSRSFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYADNILRLKSKQ---SEPPINFIQCSQL-----------HQVTSCAWVPDGCQLFTGSKCGVITAYSNRFTSTTPSEMEVESQVH----LYGHTGEVTSLFVCKPYSILISVSNDGTCILWD---LNRLCYV-------------------------------QSLTGHKSPVTAVSASETTGDIAT-------VCNSEGGGSDLRLWTVNGDLIGHVHCRETICSVAFSNQPEGVSVNVIAGGLENGVVRLWSTWDLKPVREITFPK--SSKPIISLTYSCDGHHLYTANSEG 3524
BLAST of Lysosomal trafficking regulator vs. TrEMBL
Match: A0A3B4ZMN3 (Lysosomal trafficking regulator OS=Stegastes partitus OX=144197 PE=4 SV=1) HSP 1 Score: 441.039 bits (1133), Expect = 7.035e-120 Identity = 333/1148 (29.01%), Postives = 546/1148 (47.56%), Query Frame = 1
Query: 7444 VFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFAISPDFSVEDLNEDNRNLW--VKENEFKLN--------AYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHE-FISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYD-----ELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMT--SKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQXXXXXXXXXXXXIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQYISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESG 10830
+ C++ + +G LL+ L L R EA++ VF + D +++ L L L + ++L K S + E+ + + + ++L +KE +FK A++KK S N Q D + ++S + N R+ ++ + I +I+ ++ W+ L+ T ++ +W D ++LDP EGP+R RRR+ + I +KY Q + + +L+FLFE DK + E I+ + CI V S GE +GK + F+ED + + E P++ +W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD + I PN + + + W G++SNF+YLT LN AGRS+ND+MQYPVFPFIL +YTS T+DL S YR+LSKPI++Q+ ++ ++ + +EY++ +R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES VS L W+DLVFG KQ GKAA++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF N +I P+ + + M ++ + +K+ C + L + G++WG++VGSP+ + G+L LPT + S++ M++ + V + T+ + + A N R++ P N +Q L V S A ++F G + G+IT Y + + V++ H L GH E+ L +C +++L S +WD L L Y+ Q + + V+A+S SET GD I+ + + S++ L+T+NG + + + S++++ EG +VN IA + G + + S+W+L+ V ++ P+ S PI ++ Y+ G LY N G
Sbjct: 2621 ILWSCRDTFRVQIGRLLVHTLSPALPLSDRKEALEFVFDPRHLD-ILKESLSPGLEHGPKLSLYLYEMLHDHKDSLTKDEQSAVGVFMTSLKLCGHRCIPPNAPHKQDLLKAIKEEKFKYESEEKTSKVAWEKKMASTQRNLIQRLDGKSKDISKIAADITQNVSL--RQGMERKKVIQHIRGLYKTDLSASRHWQELVQQLTHDRAVWYDQTSYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYLL----KDRRQPEDTVKPALSFLFE-----DKTHSSFSSTVKDKATSESIRFTRRCISVAPSRETAGELLLGKSGMYFVEDNAADAHDNQSLHGETEAPSF-------SWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKFRDDVYHNILTSDLPNLLEHGNITALTQLWGSGQISNFEYLTHLNKHAGRSFNDLMQYPVFPFILRDYTSETVDLQDPSIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGIR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAVQAINVFHPATYF-GMDVSSVEDPVQRRALETMIKTYGQTPRQLF----------NASHISRAGPKLMMEG-------ELPAAMGLLVQLAFRETREQAKEIACPSPLPWIKGLKWGEYVGSPSAPDPV-VCFSQPHGERFGSLLALPTRAICGLSRKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYADNILRLKSKQ---SEPPINFIQCSQL-----------HQVTSCAWVPDGCQLFTGSKCGVITAYSNRFTSTTPSEMEVESQVH----LYGHTGEVTSLFVCKPYSILISVSNDGTCILWD---LNRLCYV-------------------------------QSLTGHKSPVTAVSASETTGD--IATVCDSEGGG----SDLRLWTVNGDLIGHVHCREIICSVAFSNQPEGVSVNVIAGGLENGVVRLWSTWDLKPVREITFPK--SSKPIISLTYSCDGHHLYTANSEG 3662
BLAST of Lysosomal trafficking regulator vs. TrEMBL
Match: A0A087YNC9 (Lysosomal trafficking regulator OS=Poecilia formosa OX=48698 PE=4 SV=2) HSP 1 Score: 440.269 bits (1131), Expect = 1.279e-119 Identity = 334/1161 (28.77%), Postives = 551/1161 (47.46%), Query Frame = 1
Query: 7444 VFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEH----VKRSGNQTEEFIKSLSQLLFAISP-------DFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHE-FISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGES----LTFLFE-------STYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEY-----DELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMT--SKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQXXXXXXXXXXXXIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQ-YISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESG 10830
+ CK+ + +G LL+ L L R EA++ VF + D + G G + + + +H K + F+ SL + P D ++ + ED +E K A++KK + N Q D + ++S + N R+ ++ + I +I+ ++ W+ L+ T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ E+ L+FLFE S+ DK E+ I+ + C V S GE +GK + F+ED + + E P++ +W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD + I PN ++ + + W+ G+++NF+YLT LN AGRS+ND+MQYPVFPFIL++Y S T+DL + YR+L+KPI++Q+ ++ ++ + +EY++ +R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES +VS L W+DLVFG KQ GKAA+ AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + +I TAP+ + + M ++ + +K+ C + L + G++WG++VGSP+ + G+L LPT + S+ M++ + V + T+ + + A N R++ P N +Q L V S A ++F G + G+IT Y + + V++ H L GH E+ L +C +++L S +WD L L Y+ Q + + V+A+S SET GD+ NS+ S++ L+T+NG + + T+ S++++ EG +VN IA + G + + S+W+L+ V ++ P+ S PI ++ Y+ G LY N G
Sbjct: 2695 ILWSCKDTFRVQIGRLLVHTLSPSLPLQDRKEALEFVFDHKHIDILKESLSPGLEHGPKLSLYLFEMLHDHKDELTKEEQSAVGVFMTSLKLCGYRCIPLNVPHKHDL-LKAIKEDKMKFEAEEKTSK-AAWEKKMANTQKNLIQRLDGKSKDISKIAADITQNVSL--RQGMERKKVIQHIRGLYKTDLSASRHWQELVQQLTHDRAVWYDQTSYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LKDRRKPEETVKPPLSFLFEDKTHSFFSSTVKDKATSES------------IRFTRRCTSVAPSRETSGELLLGKSGMYFVEDNAADAHDSQILQGETEAPSF-------SWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKFRDDVYHNILTSDLPNLLEHGNILALTQLWSSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILSDYVSETIDLQDANIYRNLNKPIAVQSKEKEDRYVDNYRYLEEEYKKGIR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESEHVSQTLCQWIDLVFGLKQKGKAAVHAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLF----------SATHISRTAPKLMMEG-------ELPAAMGLLVQLAFRETREHAKEIVCPSPLPWIKGLKWGEYVGSPSAPDPV-VCFSQPHGERFGSLLALPTRAICGLSRSFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYADNILRLKSKQ---SEPPINFIQCSQL-----------HQVTSCAWVPDGCQLFTGSKCGVITAYSNRFTSTTPSEMEVESQVH----LYGHTGEVTSLFVCKPYSILISVSNDGTCILWD---LNRLCYV-------------------------------QSLTGHKSPVTAVSASETTGDIAT-------VCNSEGGGSDLRLWTVNGDLIGHVHCRETICSVAFSNQPEGVSVNVIAGGLENGVVRLWSTWDLKPVREITFPK--SSKPIISLTYSCDGHHLYTANSEG 3736
BLAST of Lysosomal trafficking regulator vs. TrEMBL
Match: A0A3Q4HV96 (Lysosomal trafficking regulator OS=Neolamprologus brichardi OX=32507 PE=4 SV=1) HSP 1 Score: 438.728 bits (1127), Expect = 3.789e-119 Identity = 339/1151 (29.45%), Postives = 557/1151 (48.39%), Query Frame = 1
Query: 7444 VFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFAISPDFSVEDLNEDNRNLW--VKENEFKLNAYKKKFK----SKLDNWNQNTDRRFNEVSIQM-KNSYNNYRTYA-RKNLQHE-FISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGES----LTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYD-----ELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSK---MTSKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQXXXXXXXXXXXXIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQYISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESG 10830
+ C++ + +G LL+ L L R EA++ VF + D +++ L L L + ++L K + + E+ + + + ++L +KE +FK A +K K K+ N +N +R + S + K + + +T + R+ ++ + I +I+ ++ W+ L+ T ++ +W D ++LDP EGP+R RRR+ + I +KY ++D+ S E+ L+FLFE DK + E I+ + CI V S GE +GK + F+ED + + E P++ +W +I+ V +R ++LRD A+E+ + +GR L+A +++ RD + I PN + + + W G++SNF+YLT LN AGRS+ND+MQYPVFPFIL +YT+ TLDL + YR+LSKPI++Q+ ++ ++ + +EY++ +R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES VS L W+DLVFG KQ GKAA++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF N +I T+ + ++ + G ++S E +K+ C + L + G++WG++VGSP+ + G+L LPT ++SK L M+ +E V + T+ + + A N R++ P N +Q L V S A ++F G + G+IT Y + + V++ H L GH E+ L +C +++L S +WD L L Y+ Q + + V A+S SET GD I+ + + S++ L+T+NG + + + SL+++ EG +VN IA + G + + S+W+L+ V ++ P+ S PI ++ Y+ G LY N G
Sbjct: 2671 ILWSCRDTFRVQIGRLLVHTLSPALPLSDRKEALQFVFDPKHLD-ILKESLSPGLEHGPKLSLYLYEMLHDHKDNLTKEEQSAVGVFMTSLKLCGHRCIPPNAPHKQDLLKAIKEEKFKYEAEEKTSKVAWEKKMANAQRNLIQRLDGKSKDISKIAADITQTVSLRQGMERKKVIQHIRGLYKTDLSASRHWQELVQQLTHDRAVWYDPTSYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYL--------LKDRRKSEETVKPPLSFLFE-----DKTHSSFSSTVKDKATSESIRFTRRCISVAPSRETAGELLLGKCGMYFVEDNAADAHDNQSLHGETEAPSF-------SWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNSKFRDDVYHNILTSDLPNLLEHGNITALTQLWGSGQISNFEYLTHLNKHAGRSFNDLMQYPVFPFILRDYTNETLDLQDPNIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGIR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLF----------NTSHISRTSTKLMEGELPAAMGLLVQLAFRESREP--------AKEIVCPSPLPWIKGLKWGEYVGSPSAPDPV-VCFSQPHGERFGSLLALPTRAICGLSSKFCLMMIYSKE-QGVRSMHSTDIQWSAILSWGYADNILRLKSKQ---SEPPINFIQCSQL-----------HQVTSCAWVPDGCQLFTGSKCGVITAYSNRFTSTTPSEMEVESQVH----LYGHTGEVTSLFVCKPYSILISVSNDGTCILWD---LNRLCYV-------------------------------QSLTGHKSPVMAVSASETTGD--IATVCDSEGGG----SDLRLWTVNGDLIGHVHCREIICSLAFSNQPEGVSVNVIAGGLENGVVRLWSTWDLKPVREITFPK--SSKPIISLTYSCDGHHLYTANSEG 3711
BLAST of Lysosomal trafficking regulator vs. Ensembl Cavefish
Match: lyst (lysosomal trafficking regulator [Source:ZFIN;Acc:ZDB-GENE-070702-1]) HSP 1 Score: 411.764 bits (1057), Expect = 2.263e-114 Identity = 295/971 (30.38%), Postives = 469/971 (48.30%), Query Frame = 1
Query: 7936 EFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYF--NPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPR-NIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMT--SKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQXXXXXXXXXXXXIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQYISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESG 10830
+ I +I+ ++ W+ L+ T ++ +W D + ++LDP EGP+R RRR+ + I +KY + P V+ SL FLFE DK + E I+ + CI V S GE +GK + F+ED E P+ + W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD + I PN + + + W +++NF+YLT LN AGRS+ND+MQYPVFPFIL +Y S TLDL + YR+LSKPI++Q+ ++ ++ + +EY++ R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R N +V+ V LP W+ D RLF LIHR +LES VS L W+DLVFG KQ GKAA+ AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF N +I P+ ++ + G ++S E +K+ + L + G++WG++VGSP+ + E G+L LPT + S++ M++ + V + T+ + + N R++ P N +Q L A ++F G + G+IT Y + V++ H L GH E+ L +C +++L S IWD L L Y+ Q + + V+A+S SET GD+ +V S++ L+T+NG + + + S++++ EG +VN IA + G + + S+W+L+ V ++ P+ + PI ++ ++ G LY N G
Sbjct: 2800 KVIQHIRGLYKTDLSASRHWQELVQQLTHDRAVWYDQSCYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYLLKDRHKPEDTVK------ASLAFLFE-----DKTHSSFSSTVKDKATSEPIRFTRRCISVAPSRETAGELLLGKSGMYFVEDNAA-------ETPHGETEPASFCWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKFRDDVYHNILTSELPNLLEYDNISALTQLWGSSQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILRDYVSETLDLQDPNIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGAR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNSERVNHVNLPPWARNDPRLFVLIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAIHAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLF----------NATHISRAGPKLMMEGELPAAMGLLVQLAFRESREQ--------AKEVTYPSPLPWIKGLKWGEYVGSPSAPDPVVCFSQPHGERF-GSLLALPTRAICGLSRKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYTDNMLRLKSKQ---SEPPINFIQCSPLHQVTS-----------CAWVPDGCQLFTGSKCGVITAYSNRFSTTMASEMDVESQVH----LYGHTDEVTGLFVCKPYSILISVSRDGTCIIWD---LNRLCYV-------------------------------QSLTGHKSPVNAVSASETTGDIATV----CDSVGGG--SDLRLWTVNGDLIGHVHCREIICSVAFSNQPEGVSVNVIAGGLENGVVRLWSTWDLKPVREITFPK--SNKPIISLTFSCDGHHLYTANSEG 3664
BLAST of Lysosomal trafficking regulator vs. Ensembl Cavefish
Match: wdfy3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:103029491]) HSP 1 Score: 273.863 bits (699), Expect = 1.390e-72 Identity = 149/386 (38.60%), Postives = 223/386 (57.77%), Query Frame = 1
Query: 8470 DIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNAN-------RKPR------------LI---DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKI 9558
DI+ V +RR+ L+ A+E+ DGRN L+A + R+++ ++P A+ ++P L+ + + W G++SNF YL LNT AGRSYND+MQYPVFP+IL +Y + LDL T+R+LSKP+ Q ++ +Y+++ + + N P YHY + YS++ V Y++R+ PFTQ F++ Q G FD DRMFH++ +W ++ +KE+IPEFFYLPE +NS +F+ G + NGT++ DVILP W+ GD R F +HR +LE YVS L+ W+DL+FGFKQ G A+EA+N+FH Y + I + ++ +A I N+GQIPKQLF K P K++
Sbjct: 2586 DIKEVHKRRYLLQPMAVEVFSGDGRNYLLAFQKGV-RNKVYQRFLAVVPSLADSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDAEELDLNNPKTFRNLSKPMGAQT-----------DDRLIQYKKRFKDWEDPNG-------ETPAYHYGTHYSSAMIVASYLLRMEPFTQIFLRLQGGHFDLADRMFHSVREAWLSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGSKQNGTRLGDVILPPWAKGDPREFIRVHRQALECDYVSAHLHEWIDLIFGFKQQGPPAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLF-KKPHPPKRV 2951
BLAST of Lysosomal trafficking regulator vs. Ensembl Cavefish
Match: nbeal1 (neurobeachin-like 1 [Source:ZFIN;Acc:ZDB-GENE-130530-544]) HSP 1 Score: 266.159 bits (679), Expect = 2.577e-70 Identity = 186/591 (31.47%), Postives = 296/591 (50.08%), Query Frame = 1
Query: 7993 WKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVD--------------KIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILS--FIENILPPNANRKPRLI----DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGE-RLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAK----KINWRNIK-NTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTL 9687
WK E+ W D +K ++L E SR+R ++++ + + + VQ + + ESL L E+ QV + +D + E + +S C LV + G + I F + S ++ +DF W L+ I + RR+ LR ALE+ + D N + + R+++ S + LP + R P+ + + ++W ++SNFDYL LNT AGR+YN++ QYPVFP+IL +YTS LDL+ +RDLSKP+++ N EK EK + ++ + ID +HY + YSN+A V++Y+IR+ PFT IQ Q G FD DR FH++ ++W + + +KE+IPEFFY PE N F+ G +++ +V+DV+LP+W+ F HR +LES YVS L+ W+DL+FG+KQ G AA+EA+N+F+ TY A+ D IT+E R A+E MI N+GQ P QL + + P + ++ R + ++ P N+ + K + + I NC +K +
Sbjct: 1821 WKAARRELMSERGPWVDKKQKEMHWKLSSAENYSRMRLKLVRNYNFDTHREASALRDNLGVQQQQVNTESL--LLEAVKQVKVSDLEEEILELPEEEQTGNTQVDDEDANQKEKLVMSEDCELVTVVDVYPGRLDITTHHIYFYD-------SSTEKEEGVGQDF---KWPLSQIREIHLRRYNLRRSALEIFLIDQTNYFLNFKKEV-RNKVYSRMLLLCSLPLHGTRSPQELLKASGLTQKWVNREISNFDYLMQLNTIAGRTYNNLAQYPVFPWILADYTSEELDLSDPCVFRDLSKPVAVLN----EKNAKAVREKYESFE------DPTGTIDR--------FHYGTHYSNAAGVMHYLIRVEPFTSLHIQLQSGRFDCADRQFHSIPATWQTLIDNPNDVKELIPEFFYFPEFLENQNGFDLGRLQISKERVNDVVLPKWAKSPED-FIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCTYEGAVDLDAITDEKERKALEGMISNFGQTPCQL-LKEPHPVRLSLEELEKRTSRLDSCPLNVFEHLTELKSF-----FVEGISDNCALVKAV 2373
BLAST of Lysosomal trafficking regulator vs. Ensembl Cavefish
Match: nbeal2 (neurobeachin-like 2 [Source:NCBI gene;Acc:100330830]) HSP 1 Score: 254.218 bits (648), Expect = 1.019e-66 Identity = 154/411 (37.47%), Postives = 235/411 (57.18%), Query Frame = 1
Query: 8464 LNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPN----ANRKPRLI----DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFG-ERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFP---AKKINWRNIK-NTAPRNIQHSFSSDKGYQDTDQMKDSI 9657
L+ + V RR+ LR ALE+ D + I + R+++ S I + PPN +R P+ + ++ ++W ++SNF+YL LNT AGR+YND+ QYPVFP++L +YTSS LDL + +RDLSKPI + N + V EK + ++ + +D+ +HY + YSN+A V++YMIR+ PFT IQ Q G+FD DR FH++A++W S + +KE+IPEFFY PE N FN G ++N +V++V+LP W+S F HR +LES +VS L+ W+DL+FG+KQ G A+EA+N+F+ TY A+ D I E R A+E +I N+GQ P QL P A+ + R + +T P N+ ++ D+++D +
Sbjct: 2039 LSQLREVHLRRYNLRRSALELFFIDQAHYFINFRKKV-RNKVYSRILGLRPPNLFYFGSRSPQELLKASNLTQKWVCREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLCDYTSSVLDLEDPAVFRDLSKPIGVVNPRHAQNV----REKYESFE------DPTGTVDK--------FHYGTHYSNAAGVMHYMIRMEPFTTLHIQLQSGKFDCADRQFHSVAAAWQARMESPADVKELIPEFFYFPEFLDNMNGFNLGCLQVNQEQVNNVVLPRWASSRED-FIRKHRKALESEHVSAHLHEWIDLIFGYKQRGPEAVEALNVFYYCTYEGAVDLDAIANETERKALEGIISNFGQTPCQLLKEAHPPRMSAENASRRQSRIDTLPPNL---------FEQLDKLRDGV 2420
BLAST of Lysosomal trafficking regulator vs. Ensembl Cavefish
Match: lrba (LPS-responsive vesicle trafficking, beach and anchor containing [Source:ZFIN;Acc:ZDB-GENE-090311-19]) HSP 1 Score: 243.047 bits (619), Expect = 2.257e-63 Identity = 139/377 (36.87%), Postives = 210/377 (55.70%), Query Frame = 1
Query: 8458 WHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFI------ENILPPNANR----KPRLI----DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFP 9546
W +I V RR+ L++ ALE+ + + + +++ + N P R P+ + + + W ++SNF+YL FLNT +GR++ND+ QYPVFP+++T Y + LDLT S YRDLSKPI G L K F+++ + ++ DE VP +HY + YS ++ + +++RI PFT F+ FQ G+FD DR F +++ +W S +KE+IPEFFYLPE+FVNS ++N G +GT V DV LP W+ F I+R +LES +VS QL+ W+DL+FG+KQ G A+ ++N+F+ TY A+ IT+ + R AVE I ++GQ P QL I P
Sbjct: 1981 WLFTEIRAVFSRRYLLQNTALEIFLANRTAVMFNFADAATVKKVVHCLPRVGVGTNYGLPQTRRISLATPKQLFKASSMTQRWQRREISNFEYLIFLNTISGRTFNDLNQYPVFPWVITNYDTEDLDLTLPSNYRDLSKPI----GALNPKRAAFFSDRFESWE------------DEQ----VPKFHYGTHYSTASFTMMWLLRIEPFTTFFLNFQGGKFDHADRTFSSISRAWRNCQRDTSDVKELIPEFFYLPEMFVNSNNYNLGVMDDGTVVSDVELPPWAKSPEE-FVRINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRSLNVFYYLTYEGAVNLSTITDPMLREAVESQIRSFGQTPCQLLIEPHSP 2336
BLAST of Lysosomal trafficking regulator vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000320.1 (pep scaffold:Pmarinus_7.0:GL481331:460:21348:1 gene:ENSPMAG00000000288.1 transcript:ENSPMAT00000000320.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 259.225 bits (661), Expect = 1.452e-74 Identity = 149/394 (37.82%), Postives = 221/394 (56.09%), Query Frame = 1
Query: 8482 VLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILP-------------PNANRKPR------LI---DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTS--STLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAP 9588
V +RR+ L+ A+E+ DGRN L+ + R+++ I P PNA+ + L+ + + W G++SNF YL LNT AGRSYND+MQYPVFP+IL +Y S LDLT T+RD+SKP+ Q E+ +++Q++ + + N P YHY + YS++ V Y++R+ PFTQ F++ Q G FD DRMFH++ +W ++ + +KE+IPEFFYLP+ NS +N G + NG + +V+LP W+ GDAR F +HR +LE YVS L+ W+DL+FG KQ G A+ + N+FH Y + IT+ ++ +A I N+GQIPKQLF K PAK++ + +T P
Sbjct: 35 VHKRRYLLQPMAVEVFSNDGRNYLLVFPRGV-RNKVYQRFLTIAPSLADSSESVSGQNPNASVEAGSGLLSGLVGERSVTQRWVHGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYQSEEQELDLTDPRTFRDMSKPMGAQT-----------MERLEQFQKRYQDWEDPNG-------ETPAYHYGTHYSSAMIVASYLVRMEPFTQTFLRLQGGHFDLADRMFHSVRDAWLSASRNNMADVKELIPEFFYLPDFLQNSNHYNLGCKQNGIWLGEVLLPNWAKGDAREFIRVHREALECDYVSAHLHEWIDLIFGCKQQGPMAVASTNVFHHLFYEGQVDIYSITDPLKLTATIGFINNFGQIPKQLF-KKPHPAKRVGSKPSGDTNP 408
BLAST of Lysosomal trafficking regulator vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000322.1 (pep scaffold:Pmarinus_7.0:GL481331:12961:21303:1 gene:ENSPMAG00000000288.1 transcript:ENSPMAT00000000322.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 245.743 bits (626), Expect = 2.576e-71 Identity = 130/310 (41.94%), Postives = 188/310 (60.65%), Query Frame = 1
Query: 8668 EGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTS--STLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAP 9588
G++SNF YL LNT AGRSYND+MQYPVFP+IL +Y S LDLT T+RD+SKP+ Q E+ +++Q++ + + N + P YHY + YS++ V Y++R+ PFTQ F++ Q G FD DRMFH++ +W ++ + +KE+IPEFFYLP+ NS +N G + NG + +V+LP W+ GDAR F +HR +LE YVS L+ W+DL+FG KQ G A+ + N+FH Y + IT+ ++ +A I N+GQIPKQLF K PAK++ + +T P
Sbjct: 2 HGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYQSEEQELDLTDPRTFRDMSKPMGAQT-----------MERLEQFQKRYQDWEDPNGSE------TPAYHYGTHYSSAMIVASYLVRMEPFTQTFLRLQGGHFDLADRMFHSVRDAWLSASRNNMADVKELIPEFFYLPDFLQNSNHYNLGCKQNGIWLGEVLLPNWAKGDAREFIRVHREALECDYVSAHLHEWIDLIFGCKQQGPMAVASTNVFHHLFYEGQVDIYSITDPLKLTATIGFINNFGQIPKQLF-KKPHPAKRVGSKPSGDTNP 293
BLAST of Lysosomal trafficking regulator vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007035.1 (pep scaffold:Pmarinus_7.0:GL477366:176480:246408:1 gene:ENSPMAG00000006333.1 transcript:ENSPMAT00000007035.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 244.973 bits (624), Expect = 1.212e-67 Identity = 145/386 (37.56%), Postives = 213/386 (55.18%), Query Frame = 1
Query: 8458 WHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILP----------PNANR----KPRLI----DIQREWAEGKMSNFDYLTFLNTAA-----GRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFP 9546
W +++E + RR+ L++ ALE+ + + + L I+ + ++LP P A R PR + ++ + W + +SNF+YL FLNT A GR+YND+ QYPVFP+++ Y S LDLT S +RDLSKP+ N P R V F E+ + ++ D +P +HY + YS +A VL +++R+ PFT F+ Q G+FD DR F ++A +W S S +KE+IPEFFYLPE+F NS D+N G G V DV+LP W+ F I+RA+LES VS QL+ WVDL+FG+KQ G A+ A+N+++ TY A+ I + + R AVE I ++GQ P QL + P
Sbjct: 23 WLFSEVEAIFSRRYLLQNTALEIFLSSRTSIMF----NLPDATIVKSVVHLLPRVGIGTLYGLPQARRYSLASPRQLFKASNMTQRWQQRDVSNFEYLMFLNTIAACTDPGRTYNDLNQYPVFPWVIANYDSEELDLTLPSNFRDLSKPVGALN-PQRAAV---FAERYASW----------DDAD------IPAFHYGTHYSTAAFVLMWLLRVEPFTNYFLSLQGGKFDHADRTFSSVARAWRNSQRDTSDVKELIPEFFYLPEMFTNSNDYNLGVTDAGVAVGDVVLPPWAK-TGEEFVRINRAALESEIVSCQLHQWVDLIFGYKQRGPEAIRAMNVYYYLTYEGAVNMASIRDRVTREAVEAQIRSFGQTPAQLMVEPHAP 383
BLAST of Lysosomal trafficking regulator vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000006.1 (pep scaffold:Pmarinus_7.0:GL476426:99633:131478:1 gene:ENSPMAG00000000006.1 transcript:ENSPMAT00000000006.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 221.476 bits (563), Expect = 1.572e-57 Identity = 129/365 (35.34%), Postives = 191/365 (52.33%), Query Frame = 1
Query: 8440 DFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLE--------------------------RDRILSFIENILPPN----ANRKPRLI----DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGE-RLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTY 9429
DF W L ++ RR+ LR ALE+ D + + + R+R+ S I + PPN +R P+ + I ++W ++SNF+YL LNT AGR+YND+ QYPVFP++L++YTS LDL+ +RDLSKPI I + +R + ++ E + +HY + YSN+A V++YMIR+ P T IQ Q G FD DR FH++ ++W S + +KE+IPEFFY PE N F+ G +++ V++V+LP W+ F HRA+LES +VS L+ W+DL+FG+KQ G AA+EA N+F+ TY
Sbjct: 1792 DFKCPLWQLREVHL---RRYNLRRSALEIFFIDQTSYFLNFTKEISCSLYYGTGWYDLPDVHGVYHTTHLHVRNRVYSRIVGLRPPNLVYYGSRSPQELLKASGITQKWVNREISNFEYLMKLNTIAGRTYNDLAQYPVFPWVLSDYTSDELDLSNPGVFRDLSKPIGIVS------------------ERNAKEVKDRYENFEDTTGTTGKFHYGTHYSNAAGVMHYMIRVEPLTTLHIQLQSGRFDCADRQFHSIPATWQALMDSPNDVKELIPEFFYFPEFLENQNGFDLGTLQMSRETVNNVVLPRWAKSPDD-FIRKHRAALESEFVSAHLHEWIDLIFGYKQRGPAAVEAHNVFYYCTY 2134
BLAST of Lysosomal trafficking regulator vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003512.1 (pep scaffold:Pmarinus_7.0:GL476505:6657:94563:1 gene:ENSPMAG00000003156.1 transcript:ENSPMAT00000003512.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 158.688 bits (400), Expect = 2.153e-38 Identity = 109/367 (29.70%), Postives = 175/367 (47.68%), Query Frame = 1
Query: 7753 EDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHE-FISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGES-----LTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKP 8835
E NR WV+ ++ + +++ ++ R EV+ R R+ L+ + I++I+ +E + W+ L T E+ +W ++LDP EGP+R RRR+ + I +KY ++D+ +S L+FLF+ DK + E + + CI V S GE +G+ + F+ED + +E + F +W DI+ V R ++LRD ALE+ + +GR L+ +ST RD++ I + PN L + + W G+++NF+YLT LN AGRS+ND+MQYPVFPF+L +Y S TLDL YR L +P
Sbjct: 2882 ESNREAWVR----RMTTNGQALLGRIETRARSVSRVAAEVT---------QRVAGRQGLERKKVIAHIREAYKAELSAQRCWQTLFRQLTHERVVWFFPVACPSSWQLDPTEGPNRERRRLQRCHITIPNKYL--------LKDRWTSAADAIKLPLSFLFD-----DKSSSSGSSAVKDKATSEPTKFTRRCISVVPSRETPGELLLGETGMHFVEDSTGDA-TETPSCVGEAEALSF-SWTYEDIKEVHLRWWQLRDNALEVFLTNGRTLLLTFDSTKVRDQVYQTILSSDLPNLLEYGNLSALTQLWCAGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFVLRDYASETLDLADPRVYRSLVRP 3220
BLAST of Lysosomal trafficking regulator vs. Ensembl Yeast
Match: BPH1 (Protein homologous to Chediak-Higashi syndrome and Beige proteins; both of which are implicated in disease syndromes in human and mouse, respectively, due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting [Source:SGD;Acc:S000000628]) HSP 1 Score: 246.514 bits (628), Expect = 2.615e-65 Identity = 141/411 (34.31%), Postives = 224/411 (54.50%), Query Frame = 1
Query: 8422 LPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENI---LPPNA-----------------------------------NRKPRLID---IQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF 9528
+ +LK F+ W L DI +V +R F LRD A+E++ K+ + + + RD +L + I LP + + LID I ++W G++SNF YL +N AGRS+ND+ QYPVFP+++ +Y S+ LDL TYRDLSKP+ Q +EK R+L+ ++ + + P+HY + YS++ V Y+IR+ PF + F+ Q G F DR+F ++ +W ++S + ++E+ PEFF+LPE +N ++FG +G KVDDV+LP W++GD ++F +R +LESPYVS L+ W+DL+FG+KQ G A++++N+F+ +Y A+ D I +E R A+ +I N+GQ P Q+F
Sbjct: 1440 VSTFLKHEVFV-WKLLDITFVTKRPFLLRDVAIELLFKERVSAFFSFYNKRVRDDVLRVLNKIPKHLPADPIFSSVLQEINDRGNSIVARNGIGKASIASKFTSVFSANNSLIDGFEISKKWVRGEISNFYYLLSINILAGRSFNDLTQYPVFPWVIADYESNVLDLENPKTYRDLSKPMGAQ------------SEK-----RKLQFIERYEALASLENADSAPFHYGTHYSSAMIVSSYLIRLKPFVESFLLLQGGSFGPADRLFSSLERAWSSASSENTTDVRELTPEFFFLPEFLINVNSYDFGTDQSGKKVDDVVLPPWANGDPKVFIQKNREALESPYVSAHLHEWIDLIFGYKQKGDIAVKSVNVFNRLSYPGAVNLDNIDDENERRAITGIIHNFGQTPLQIF 1832
BLAST of Lysosomal trafficking regulator vs. Ensembl Nematostella
Match: EDO33951 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQQ4]) HSP 1 Score: 262.692 bits (670), Expect = 9.045e-72 Identity = 191/611 (31.26%), Postives = 286/611 (46.81%), Query Frame = 1
Query: 7774 VKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYA----RKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPAR-NVQDKSSSGESLTFLFESTYQVDKIVY---ENPIDCQL----------LKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPN----ANRKP----RLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF 9528
+K+ E K + +F + Q++ ++ +++S + + T A R LQ ++A+ + W + T E+ W + ++L E R+R RM T +N Y S AR N D++ G++L+ + +V E D +L + +E + + C LV G+ V + F +R ++ + L W L ++ V RR LR ALE + D N I S R+ + I ++ PPN R P + + W + ++SNF+YL LNT AGR+YND+ QYPVFP++L +Y S LDL+ + YRDLSKPI + N P R K E D Y+ E + +HY + YSNSA VL+Y++R+ PFT + G FD DR FH++ + W + S +KE++PEFFY PE N F+ G G +V+ V LP W+ F HR +LES YVS L+ W+DL+FG+KQ G+ A+EA N+F+ TY A+ D IT E R A E MI N+GQ P QL
Sbjct: 30 IKQFEAKFSVLSGRFWMQCLTALQSSLKQRDQLSADGRERFARQVTKAAQELRTKLQERDKGLLRARSQQSARNAIDWLLTKRRLTSERAPWAYRTPEEVHWKLSTEETFQRMRLRM---TQNLNYSYHMEASNARDNKSDENLDGDTLSQSVPLRVAREAVVMRSLEADEDEELTASNNSVSPPMSVVEKVVLEVDCELVTLMDVMPGKLKVSTTHVYFTANRSSDAWD--------LTTVYEFTWALAELREVHLRRHNLRRSALEFFLVDQTNYFINC-SKKARNTVYKKIMSLRPPNLYYMGARSPAQLLKASGLTERWVKREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLVDYESKDLDLSNRAVYRDLSKPIGVLN-PARVK------EVEDRYKHF-----------EDPTGTIAKFHYGTHYSNSANVLFYLLRVEPFTTLHVALHSGRFDCADRQFHSIPALWDSLFNKASDVKELVPEFFYFPEFLENLNGFDLGRLQGGARVNHVTLPPWARTPEE-FVHKHRQALESEYVSTHLHDWIDLIFGYKQRGEKAVEAHNVFYYCTYEGAVDLDAITNEAERIATEGMINNFGQTPSQLL 609
BLAST of Lysosomal trafficking regulator vs. Ensembl Nematostella
Match: EDO45998 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRE1]) HSP 1 Score: 232.261 bits (591), Expect = 1.859e-62 Identity = 138/387 (35.66%), Postives = 216/387 (55.81%), Query Frame = 1
Query: 8464 LNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQRE-----WAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLP-ELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHS 9606
L+ I V++RR+ LR +E+ KD + +NS +RD+ + E + P+ N L D ++E W G ++NFDYL +LN+++ RS+ND+ QYPVFP+++ +YTSS LDL T+RDL+KPI G L +N E+ + P + Y S YS VLYY++R+ P + + Q G+FD+PDR+F+++ +W + + +KE+IPEF+ E VN Q+ G + + + V DV LP W++ D F +R +LE PYVS +LN+W+DL+FG+KQ G+ A EA N+F+ TY A+ D IT+ R+++E I +GQ PKQLF + P + ++ +P + HS
Sbjct: 177 LSQISRVVKRRYLLRHVGIEIFSKDSSQMYLVLNSQSDRDQF--YRELLKQPDVN----LDDTEQENMTLKWQNGAITNFDYLMYLNSSSDRSFNDLTQYPVFPWVIADYTSSQLDLRDPLTFRDLAKPI----GALNPNRLNQLKERCRDMTE-------------------PKFLYGSHYSTPGYVLYYLVRVAP--EFMLCLQGGKFDQPDRLFNSIQETWENVLTGHADVKELIPEFYQSSGEFLVNCQNLPLGMKQDKSNVGDVELPAWAT-DCEDFIRKNREALECPYVSERLNHWIDLIFGYKQRGEEAWEADNVFYYLTYEGAVDLDSITDPNERASLESQILEFGQTPKQLFTSP-HPQRLVSATPTMGASPSPLVHS 530
BLAST of Lysosomal trafficking regulator vs. Ensembl Nematostella
Match: EDO30379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0Y3]) HSP 1 Score: 216.083 bits (549), Expect = 3.627e-59 Identity = 114/276 (41.30%), Postives = 163/276 (59.06%), Query Frame = 1
Query: 8719 GRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFP 9546
GR+Y D+ QYPVFP+ILT Y S LDL + YRDL+KPI N R ++ ++ + DE +PP+HY + YS L ++IR+ PF +F+ Q G+FD P R F ++ +W S +KE+IPE FYLPE+F NS F FG +G +DDV LP W++ + F IHRA+LES YVS+Q++ W+DL+FGFKQ G A++A N+F TY ++ D I++ + R AVEQ I+++GQ P QL ++ P
Sbjct: 1 GRTYCDLNQYPVFPWILTNYESDKLDLKDPNNYRDLTKPIGALNP-----------------NRHVQFLERYASWDEND--DIPPFHYGTHYSTCGFTLAWLIRLEPFATQFLNLQGGKFDHPGRTFCSVQRAWQNCNRDTSDVKELIPELFYLPEMFCNSNRFTFGVDDDGMVIDDVELPSWANTPEQ-FVTIHRAALESEYVSSQIHGWIDLIFGFKQRGPEAVKATNVFFHLTYEGSVDLDSISDTVMREAVEQQIKSFGQTPSQLLLDPHPP 256
BLAST of Lysosomal trafficking regulator vs. Ensembl Nematostella
Match: EDO46742 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNV7]) HSP 1 Score: 166.392 bits (420), Expect = 8.611e-43 Identity = 82/155 (52.90%), Postives = 110/155 (70.97%), Query Frame = 1
Query: 9067 DGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF 9528
DG FD+PDR FH++A++W LS+ +KE+IPEFF+LPE N + F+FG R NG +V DV LP W+ + RLF LIHR +LE+ VS L+ W+DL+FGFKQTGK A+EA+N+FHP TY+ + + IT+ I A++ MIE YGQ P QLF
Sbjct: 1 DGNFDQPDRTFHSLATTWRLSSYQSPTDVKELIPEFFFLPEFLENFEGFDFGFRQNGVRVMDVSLPPWAKNNPRLFILIHRQALETDIVSQHLHNWIDLIFGFKQTGKDAVEALNVFHPATYF-GVDINSITDPISNKALKTMIETYGQTPTQLF 154
BLAST of Lysosomal trafficking regulator vs. Ensembl Nematostella
Match: EDO29546 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T3B8]) HSP 1 Score: 123.635 bits (309), Expect = 1.452e-32 Identity = 66/135 (48.89%), Postives = 85/135 (62.96%), Query Frame = 1
Query: 8662 WAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQ 9066
W G +SNF+YLT LN AGR+ ND+MQYPVFPF+L+++TS LDL T RDL+KPI++QN P+ E K EY RQ S A P HYSS YSNS TVL++++R+PPFT +Q+Q
Sbjct: 2 WRAGTLSNFEYLTELNKMAGRTCNDLMQYPVFPFVLSDFTSEVLDLNDPKTLRDLTKPIAVQN-PIMEA-------KYKEYYRQ----------QGESDPAAAPCHYSSHYSNSGTVLHFLVRLPPFTNMLLQYQ 118
BLAST of Lysosomal trafficking regulator vs. Ensembl Medaka
Match: lyst (lysosomal trafficking regulator [Source:NCBI gene;Acc:101170120]) HSP 1 Score: 382.874 bits (982), Expect = 1.196e-105 Identity = 258/799 (32.29%), Postives = 419/799 (52.44%), Query Frame = 1
Query: 7444 VFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEE------FIKSLSQLLFAISPDFSV--EDLNEDNRNLWVKENEFKLNA--------YKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYF--NPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNN------LYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPN 9765
+ C++ K +G LL+ + L L R EA++ VF + + +++ L L L + ++L H R G +E F+ SL P + +DL + +KE +FK A ++KK + N Q D + ++S + N + + + + I +I+ ++ W+ L+ T ++ +W + N ++LDP EGP+R RRR+ + I +KY + P V+ L+FLFE DK + E I+ + C+ V S GE +GK + F+ED + L+ E E P++ +W +I+ V +R ++LRD A+E+ + +GR L+A ++T RD + I PN + + + W G+++NF+YLT LN AGRS+ND+MQYPVFPF+L++YTS TLDL + + YR+LSKPI++Q+ ++ ++ + +EY++ +R ++ + V PYHY S YSNS TVL++++R+PPFT+ F+ +QD FD PDR FH+M ++W LS+ +KE+IPEFFYLPE VN + F+FG R NG +V+ V LP W+ D RLF LIHR +LES +VS L W+DLVFG KQ G+AA++AIN+FHP TY+ + + + ++R A+E MI+ YGQ P+QLF + ++ T P+ + + M ++ + +K+ C + L + G++WG++VGSP+
Sbjct: 2763 ILWSCRDTFKVQIGRLLVHSLSTALPLSDRKEALEFVFDSKHLE-ILKESLSPGLEHGPKLSLYLYEML-HDHRDGLTKDEQGAVGVFMTSLKLCGHRCIPPSAPHKQDLLKA-----IKEEKFKYEAEEKNSKVAWEKKMVNAQRNLIQRLDGKLKDISKIAADITQNV-SLQQGQERKKVIQHIRGLYKTDLSASRHWQELVQQLTHDRAVWYNQNSYPTSWQLDPTEGPNRERRRLQRCYLTIPNKYLLLDRRKPEEAVKPP------LSFLFE-----DKTHSSFSSTVKDKATSESIRFTRRCVSVAPSRETAGELLLGKSGMYFVEDNAADAQDSQILHGE-TEAPSF-------SWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKFRDDVFHNILTSDLPNLLEYGNITALTQLWGSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFVLSDYTSETLDLQEANIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGIR--------EDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFVLIHRQALESDHVSQTLCQWIDLVFGLKQKGRAAVQAINVFHPATYF-GMDVSAVEDPVQRRALETMIKTYGQTPRQLF----------SASHMSRTGPKLMMEG-------ELPAAMGLLVQLAFRETREQAKEVVCPSPLPWIKGMKWGEFVGSPS 3508 HSP 2 Score: 53.5286 bits (127), Expect = 6.211e-6 Identity = 56/239 (23.43%), Postives = 108/239 (45.19%), Query Frame = 1
Query: 5023 VDSAIENLGGISIMIFWLAKVVESGD-EVSTRYXXXXXXXXXRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQH-------MIYEDPTKSKLSLPCNS-RLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQEPFEALEHPL---PVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHP 5703
+ S + +GG +F A+ VE D E + L+++L L + H+ GY+++ Q+ K +G+ ++ L+ ++ ED + L S + +D ++L E+L+ WK+ A K + + E LL + L+ + Y + N L G++ L++CQ E + L P +C I+II ++ +P D+ ++ +CN +L +HP
Sbjct: 1820 LQSVLHKIGGTGNFVFLFAQTVELSDCEKTQALALQVLLSLCNSNQHRIHEMDCYHGYAMIHQVLIKPKCVVGYHMLKTLLDGCCSGPILLLGED---GQFRLDAESVAVVQDLRLLSEILLDWKVWA-------KAQCGVWET--------LLAALEILIRVHHPYQVFNIRQLLNAGVVHRFLLACQVLQEHRDEHLTTIPQEVCLSFIKIIQEVLGSPPDLDLLRLICNFLLAVHP 2040
BLAST of Lysosomal trafficking regulator vs. Ensembl Medaka
Match: wdfy3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:101161316]) HSP 1 Score: 275.789 bits (704), Expect = 3.943e-73 Identity = 154/420 (36.67%), Postives = 239/420 (56.90%), Query Frame = 1
Query: 8470 DIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNAN-------RKPR------------LI---DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXC-MKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDK-GYQDTDQMKDSI 9657
DI+ V +RR+ L+ A+E+ DGRN L+A + R+++ ++P A+ ++P L+ + + W G++SNF YL LNT AGRSYND+MQYPVFP+IL +Y S +DL ++R+L+KP+ Q ++ +Y+++ + + N P YHY + YS++ V Y++R+ PFTQ F++ Q G FD DRMFH++ +W ++ +KE+IPEFFYLPE +NS +F+ G + NGTK+ DV+LP W+ GD R F +HR +LE YVS L+ W+DL+FG+KQ G A+EA+N+FH Y + I + ++ +A I N+GQIPKQLF K P K++ R+ N + +F+SDK + D ++ S+
Sbjct: 2605 DIKEVHKRRYLLQPMAVEVFSADGRNYLLAFQKGV-RNKVYQRFLAVVPSLADSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLNNPKSFRNLAKPMGAQT-----------DDRLTQYKKRYKDWEDPNG-------ETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWLSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGAKQNGTKLGDVLLPSWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPPAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLF-KKPHPPKRV--RSKANGDAAGVPPNFNSDKIFFHHLDNLRPSL 3002
BLAST of Lysosomal trafficking regulator vs. Ensembl Medaka
Match: nbeal2 (neurobeachin like 2 [Source:NCBI gene;Acc:101163272]) HSP 1 Score: 249.21 bits (635), Expect = 3.258e-65 Identity = 175/534 (32.77%), Postives = 270/534 (50.56%), Query Frame = 1
Query: 7993 WKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSS-SGESLTFLFESTYQV-----------DKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGF-INWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPN----ANRKPRLI----DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGE-RLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLF 9528
W+ L FT E+ W + + ++L E S++R +++ + D + ++ N+ +S S E + +V D + +N ++ + E + +S C L+ G V + F Y E + GF L+ + V RR+ LR ALE+ D + I + R+++ S I + PPN +R P+ + + ++W ++SNF+YL LNT AGR+YND+ QYPVFP++L +YTS TLDL+ S +RDLSKPI + N + V EK + ++ + NID+ +HY + YSN+A V++YMIR+ PFT IQ Q G FD DR FH++A++W S + +KE+IPEFFY PE N F+ G +++ V DV LP W++ F HR +LES +VS+ L+ W+DL+FG KQ G+ A+ A+N+F+ TY A+ D I E R A E +I N+GQ P QL
Sbjct: 1881 WRSLRRHFTNERGAWANRVQPEVKWKLSNAETYSKMRLKLVPNYNY--DAHCEASALRDNMGAESPRSSEPIPLAVAKEAKVSVMKDDQLGEEDLVFLDNEVEGEDESQREKLVLSEDCELITIVAVVPGRLEVTTHHLYF--------YDGSSEKEETEEGIGFDFKRPLSQLREVHLRRYNLRRSALELFFIDQSHYFINFKKKV-RNKVYSRILGLRPPNLFYFGSRSPQELLKASGLTQKWVYREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLCDYTSPTLDLSDPSIFRDLSKPIGVVNPRHAQNV----REKYESFE------DPTGNIDK--------FHYGTHYSNAAGVMHYMIRMEPFTTLHIQLQSGRFDVADRQFHSVAAAWQARMESPADVKELIPEFFYFPEFLQNMNGFDLGRLQISQEAVTDVELPRWATSRED-FIRKHRKALESEHVSSHLHEWIDLIFGCKQRGEEAVNALNVFYYCTYEGAVDLDAIANETERKAYEGIISNFGQTPCQLL 2384
BLAST of Lysosomal trafficking regulator vs. Ensembl Medaka
Match: lrba (LPS responsive beige-like anchor protein [Source:NCBI gene;Acc:101175296]) HSP 1 Score: 241.506 bits (615), Expect = 6.991e-63 Identity = 138/377 (36.60%), Postives = 209/377 (55.44%), Query Frame = 1
Query: 8458 WHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENI-------LPPN---ANRKPRLI----DIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFP 9546
W +I V RR+ L++ ALE+ M + L +++ + + LP + P+ + ++ + W ++SNF+YL FLNT +GR+YND+ QYPVFP+++T Y S LDLT S +RDLSKPI G L K F+++ + ++ VP +HY + YS S+ L +++RI PFT F+ FQ G+FD DR F +++ +W S +KE+IPEF+YLPE+FVNS ++N G +GT V +V+LP W+ F I+R +LES +VS QL+ W+DL+FG+KQ G A A+N+++ TY A+ I + + R AVE I ++GQ P QL I P
Sbjct: 1977 WLFTEIRAVFSRRYLLQNTALEVFMANRTAVLFNFPDAATVKKVVHCLPRVGVGTSFGLPQTRRISLATPKQLFKASNMTQRWQRREISNFEYLMFLNTISGRTYNDLNQYPVFPWVITNYDSEELDLTLPSNFRDLSKPI----GALNPKRAAFFSDRYESWEDD----------------QVPKFHYGTHYSTSSFTLMWLLRIEPFTTFFLNFQGGKFDHADRTFSSVSRAWRNCQRDTSDVKELIPEFYYLPEMFVNSNNYNLGVMEDGTVVSNVVLPPWAKSPEE-FVRINRLALESEFVSCQLHQWIDLIFGYKQQGPEATRALNVYYYVTYEGAVNLSSINDPMLREAVESQIRSFGQTPCQLLIEPHPP 2332
BLAST of Lysosomal trafficking regulator vs. Ensembl Medaka
Match: nsmaf (neutral sphingomyelinase activation associated factor [Source:NCBI gene;Acc:101155551]) HSP 1 Score: 218.779 bits (556), Expect = 2.092e-57 Identity = 137/375 (36.53%), Postives = 198/375 (52.80%), Query Frame = 1
Query: 8452 INWHLNDIEWVLRRRFKLRDYALEMIMKDGRNC---LIAMNSTLERDRI----LSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFV-NSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAK 9552
I L + + +RR L+ LE+ + C + +T +RD I +F+EN + + L +W G +SN+ YL LN A RS ND+ QYPVFP+++ +Y SS LDLT +T+RDLSKP+ N +R R++ + + E P + Y S YS+ VL+Y++R+ P + + Q+G +D PDRMF+ +A +W + KE+IPEF+ F+ N + + G R NG+ V DV LP W+S DA F H+A+LESP+VS L+ W+DLVFGFKQ G A A N+FHP TY I D I + +R A+ I +GQ PKQLF N P +
Sbjct: 215 IQIKLQQVRRIYKRRHGLKPLGLEVFCTENDLCSDIYLKFYNTADRDEIYYYMATFLENHITEHTAESYML-----QWQRGHISNYQYLLHLNNLADRSCNDLSQYPVFPWVIADYGSSQLDLTNAATFRDLSKPVGALNK-----------------ERLDRLLARYSGMPE------PRFIYGSHYSSPGYVLFYLVRVAP--EHMLCLQNGRYDHPDRMFNCIAETWKNCLEGATDFKELIPEFYGSDSSFLENRLNLDLGRRQNGSLVGDVSLPPWAS-DASDFLEKHKAALESPFVSEHLHEWIDLVFGFKQRGSDAEAAHNVFHPLTYEGNIDCDSIEDTDQRIAMLTQILEFGQTPKQLF-NSPHPQR 557
BLAST of Lysosomal trafficking regulator vs. Planmine SMEST
Match: SMESG000069981.1 (SMESG000069981.1) HSP 1 Score: 4343.11 bits (11263), Expect = 0.000e+0 Identity = 2316/2316 (100.00%), Postives = 2316/2316 (100.00%), Query Frame = 1
Query: 382 MLTKQFLTDLENLYMLKMDSDEKGNELDRLKAYLETEYGALMLYGIEFIIEQILIAKRNNTDSMKSSVLKIIIESELGNILATTLLSILTDMCLNTNQLIDKNFLDSITVPEFTFSQYLRQDFVRSSLFKTNIKQIRRPRPSEELSTDDNEFFPTVKIRTKRRPMKFSKYFARSDGTMNPFPFIVENQSVSEIGELCQSDMDERLYMNPISHTIETSNKVHILTSLRTAARLLYQIIQLDPSMHSDAISIYLEVLKSCCRLLNNVHSDFVSFXXXXXXXXXXXXCNIALTVSILVSEKSSSNSIMTIILGHKVTDRLLEIHQLFHEIHQDFMVLHDINKLVFYIFIIVTKNILENYSGSCRGIIHLLTGWYATGGSQIAQISLNSETSNEDFYFTLKNSKISLFSEICVLLSLLKDIPNEKRLNQIPKNSTEVFSHHSDQFNYIVTAENTDSFKDVCCYGSICYLILDNLVFLLNQDSQLKFISSRKKHIYNHILASIKTIRFCCTVDLMEFSNKLVRRLINPMPAAIKTIVISFLQRIIEISFEFYKLRFSCDCQFSSRHDVVGILQMIRNVCIPKSKEPICPLSCYNATFVELLHFIDWLGNIQDDKMKALVKENVIQPIFKRTNQYASNLHSSYCGMIGSSMFSLLPYMNYSWENDDLNLLWSACEKFPKLKRNYYKCLTITLLSTRSSPVEDSKELSMKTRIIDFLVSRVNFEILMKQMDHNSGSIKLLFEDIYIWECFRILFTYNDEFRRSMFTSNGIDCCYVMLKEIIEFISILTDENLETYKLSGFLLFESLMCLVIDGNMLKNXXXXXXXXXXXXWVQIQSSILKYFPKEESVAQSLIQSLLNCCFRHKWTVQNDLYQLRRLFLDSIVSKNISITNQGSEIDISDVGIESSFSEPXXXXXXXXXXXXXVNGSHKYDADVSSDLVNDDESELRARKKHNLRDTEGERANVFIDINTAYTNGSNMEINTDFLRLFIKIILSLPIDNYHFIGQKALESVYYSLRYIPDKNQQSFICDDFMEKMMCSIENILNSHDIPGXXXXXXXXXXXPFSCWCTAKRLRFLINLSEKNPGLKVQIIKMLIEKAELINSLQPDLSLMVPVHQNIPKSVRGWRNSNFEFYSFDEEIGDVSNYLFETKLNRPNWKGLDFDNSCENSGFSVSMWIQMDSTVEYKRRKKSGEMXXXXXXXXXXXXXXXXXXXXXXXQSIQDFIHVASIYSKDKNSSFKSQCFQIWCKPSTGTIMIRFYQRIYQTVNLDPNKPATPLPQMRESRSQIFNIFQSQTVXXXXXXXXXXXXXXXXXXXXFVLVGESMLNNVLPLNAWNFVTVSVNWKSPEVGEVFCVINGDFSYESKLIRNSHYVYQGSQSLESFFNIGQLGCPPGGSSHLKYNLGSLFIFEGAKIQTANENLSLMFLSPNWDGGSMMLNAAQRDSANTLGLVIMRILADRQVGSEFVASMLERCQNILQNNWLEKMNELITNNLVATFTCGDIPRFDVNEMCSADSEMPTLSPNYYQFSSIVSPKSETEVPVAFSSNCFSKYFIIKASVDSAIENLGGISIMIFWLAKVVESGDEVSTRYXXXXXXXXXRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQHMIYEDPTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQEPFEALEHPLPVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHPISMKDNDIDSGQYYRHLKAFTKMEVEKSTDDHNEIDGTFPEKARVCKINIQRGNHLKLNPERDITEQLSISLMGSKVSEVEKKTLQQFYVATLTDNRQDSNENNEFLDIXXXXXXXXXXXXXCPTLIDENDKNEMNSSFETSFIASNNLTDQPVISGQSESSRVHVIAGLISILENVIEVKVSDSILERCSNYDFFFEFILHLLSHTSALVRQKSLSLFRVYLYRKKSXXXXXXXXXXXXXXVSHVIHQNSTTKEILAEAISIMFGQNLFSIIMDIDWEXXXXXXXXXXXXXXXXXXXMNLELKSICKLQGIVSNQSDNIQSFAKSLDETMNSSNHFGLQYQKSAXXXXXXXXXXXXXXMLWAFKICGWLFVNHSTLLQSCLKSGFLEFMCNCPIIFYKASFTKQDPRFTAFLDLCAITSASIIVSNKIQEFSRLLEMCEILHVSALKLSKQLTKTGTINHGTGTLAHYALEKILMTIIESICIINSNDPAFNIPITSSCIQKFLFKYRLLTNQYGFQKNLNEQLSETIKSTIGIVINTEKC 7329
MLTKQFLTDLENLYMLKMDSDEKGNELDRLKAYLETEYGALMLYGIEFIIEQILIAKRNNTDSMKSSVLKIIIESELGNILATTLLSILTDMCLNTNQLIDKNFLDSITVPEFTFSQYLRQDFVRSSLFKTNIKQIRRPRPSEELSTDDNEFFPTVKIRTKRRPMKFSKYFARSDGTMNPFPFIVENQSVSEIGELCQSDMDERLYMNPISHTIETSNKVHILTSLRTAARLLYQIIQLDPSMHSDAISIYLEVLKSCCRLLNNVHSDFVSFQQQLLKLADDLLCNIALTVSILVSEKSSSNSIMTIILGHKVTDRLLEIHQLFHEIHQDFMVLHDINKLVFYIFIIVTKNILENYSGSCRGIIHLLTGWYATGGSQIAQISLNSETSNEDFYFTLKNSKISLFSEICVLLSLLKDIPNEKRLNQIPKNSTEVFSHHSDQFNYIVTAENTDSFKDVCCYGSICYLILDNLVFLLNQDSQLKFISSRKKHIYNHILASIKTIRFCCTVDLMEFSNKLVRRLINPMPAAIKTIVISFLQRIIEISFEFYKLRFSCDCQFSSRHDVVGILQMIRNVCIPKSKEPICPLSCYNATFVELLHFIDWLGNIQDDKMKALVKENVIQPIFKRTNQYASNLHSSYCGMIGSSMFSLLPYMNYSWENDDLNLLWSACEKFPKLKRNYYKCLTITLLSTRSSPVEDSKELSMKTRIIDFLVSRVNFEILMKQMDHNSGSIKLLFEDIYIWECFRILFTYNDEFRRSMFTSNGIDCCYVMLKEIIEFISILTDENLETYKLSGFLLFESLMCLVIDGNMLKNIYYYEGYSYEIIWVQIQSSILKYFPKEESVAQSLIQSLLNCCFRHKWTVQNDLYQLRRLFLDSIVSKNISITNQGSEIDISDVGIESSFSEPEDDIGGDEDDSDIVNGSHKYDADVSSDLVNDDESELRARKKHNLRDTEGERANVFIDINTAYTNGSNMEINTDFLRLFIKIILSLPIDNYHFIGQKALESVYYSLRYIPDKNQQSFICDDFMEKMMCSIENILNSHDIPGLQLILLKLLTLPFSCWCTAKRLRFLINLSEKNPGLKVQIIKMLIEKAELINSLQPDLSLMVPVHQNIPKSVRGWRNSNFEFYSFDEEIGDVSNYLFETKLNRPNWKGLDFDNSCENSGFSVSMWIQMDSTVEYKRRKKSGEMKKNKKKSNKLSANANSLSKLLLLQSIQDFIHVASIYSKDKNSSFKSQCFQIWCKPSTGTIMIRFYQRIYQTVNLDPNKPATPLPQMRESRSQIFNIFQSQTVSRWDSNDSSSLLDTNSRNSSFVLVGESMLNNVLPLNAWNFVTVSVNWKSPEVGEVFCVINGDFSYESKLIRNSHYVYQGSQSLESFFNIGQLGCPPGGSSHLKYNLGSLFIFEGAKIQTANENLSLMFLSPNWDGGSMMLNAAQRDSANTLGLVIMRILADRQVGSEFVASMLERCQNILQNNWLEKMNELITNNLVATFTCGDIPRFDVNEMCSADSEMPTLSPNYYQFSSIVSPKSETEVPVAFSSNCFSKYFIIKASVDSAIENLGGISIMIFWLAKVVESGDEVSTRYLLKLILLLIRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQHMIYEDPTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQEPFEALEHPLPVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHPISMKDNDIDSGQYYRHLKAFTKMEVEKSTDDHNEIDGTFPEKARVCKINIQRGNHLKLNPERDITEQLSISLMGSKVSEVEKKTLQQFYVATLTDNRQDSNENNEFLDIESSMESSSSEPSSCPTLIDENDKNEMNSSFETSFIASNNLTDQPVISGQSESSRVHVIAGLISILENVIEVKVSDSILERCSNYDFFFEFILHLLSHTSALVRQKSLSLFRVYLYRKKSQLQQNQNQWLSINLVSHVIHQNSTTKEILAEAISIMFGQNLFSIIMDIDWENFSIFNSSSNSSKSAEHNSMNLELKSICKLQGIVSNQSDNIQSFAKSLDETMNSSNHFGLQYQKSAILLLSILSNIDNDSMLWAFKICGWLFVNHSTLLQSCLKSGFLEFMCNCPIIFYKASFTKQDPRFTAFLDLCAITSASIIVSNKIQEFSRLLEMCEILHVSALKLSKQLTKTGTINHGTGTLAHYALEKILMTIIESICIINSNDPAFNIPITSSCIQKFLFKYRLLTNQYGFQKNLNEQLSETIKSTIGIVINTEKC
Sbjct: 1 MLTKQFLTDLENLYMLKMDSDEKGNELDRLKAYLETEYGALMLYGIEFIIEQILIAKRNNTDSMKSSVLKIIIESELGNILATTLLSILTDMCLNTNQLIDKNFLDSITVPEFTFSQYLRQDFVRSSLFKTNIKQIRRPRPSEELSTDDNEFFPTVKIRTKRRPMKFSKYFARSDGTMNPFPFIVENQSVSEIGELCQSDMDERLYMNPISHTIETSNKVHILTSLRTAARLLYQIIQLDPSMHSDAISIYLEVLKSCCRLLNNVHSDFVSFQQQLLKLADDLLCNIALTVSILVSEKSSSNSIMTIILGHKVTDRLLEIHQLFHEIHQDFMVLHDINKLVFYIFIIVTKNILENYSGSCRGIIHLLTGWYATGGSQIAQISLNSETSNEDFYFTLKNSKISLFSEICVLLSLLKDIPNEKRLNQIPKNSTEVFSHHSDQFNYIVTAENTDSFKDVCCYGSICYLILDNLVFLLNQDSQLKFISSRKKHIYNHILASIKTIRFCCTVDLMEFSNKLVRRLINPMPAAIKTIVISFLQRIIEISFEFYKLRFSCDCQFSSRHDVVGILQMIRNVCIPKSKEPICPLSCYNATFVELLHFIDWLGNIQDDKMKALVKENVIQPIFKRTNQYASNLHSSYCGMIGSSMFSLLPYMNYSWENDDLNLLWSACEKFPKLKRNYYKCLTITLLSTRSSPVEDSKELSMKTRIIDFLVSRVNFEILMKQMDHNSGSIKLLFEDIYIWECFRILFTYNDEFRRSMFTSNGIDCCYVMLKEIIEFISILTDENLETYKLSGFLLFESLMCLVIDGNMLKNIYYYEGYSYEIIWVQIQSSILKYFPKEESVAQSLIQSLLNCCFRHKWTVQNDLYQLRRLFLDSIVSKNISITNQGSEIDISDVGIESSFSEPEDDIGGDEDDSDIVNGSHKYDADVSSDLVNDDESELRARKKHNLRDTEGERANVFIDINTAYTNGSNMEINTDFLRLFIKIILSLPIDNYHFIGQKALESVYYSLRYIPDKNQQSFICDDFMEKMMCSIENILNSHDIPGLQLILLKLLTLPFSCWCTAKRLRFLINLSEKNPGLKVQIIKMLIEKAELINSLQPDLSLMVPVHQNIPKSVRGWRNSNFEFYSFDEEIGDVSNYLFETKLNRPNWKGLDFDNSCENSGFSVSMWIQMDSTVEYKRRKKSGEMKKNKKKSNKLSANANSLSKLLLLQSIQDFIHVASIYSKDKNSSFKSQCFQIWCKPSTGTIMIRFYQRIYQTVNLDPNKPATPLPQMRESRSQIFNIFQSQTVSRWDSNDSSSLLDTNSRNSSFVLVGESMLNNVLPLNAWNFVTVSVNWKSPEVGEVFCVINGDFSYESKLIRNSHYVYQGSQSLESFFNIGQLGCPPGGSSHLKYNLGSLFIFEGAKIQTANENLSLMFLSPNWDGGSMMLNAAQRDSANTLGLVIMRILADRQVGSEFVASMLERCQNILQNNWLEKMNELITNNLVATFTCGDIPRFDVNEMCSADSEMPTLSPNYYQFSSIVSPKSETEVPVAFSSNCFSKYFIIKASVDSAIENLGGISIMIFWLAKVVESGDEVSTRYLLKLILLLIRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQHMIYEDPTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQEPFEALEHPLPVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHPISMKDNDIDSGQYYRHLKAFTKMEVEKSTDDHNEIDGTFPEKARVCKINIQRGNHLKLNPERDITEQLSISLMGSKVSEVEKKTLQQFYVATLTDNRQDSNENNEFLDIESSMESSSSEPSSCPTLIDENDKNEMNSSFETSFIASNNLTDQPVISGQSESSRVHVIAGLISILENVIEVKVSDSILERCSNYDFFFEFILHLLSHTSALVRQKSLSLFRVYLYRKKSQLQQNQNQWLSINLVSHVIHQNSTTKEILAEAISIMFGQNLFSIIMDIDWENFSIFNSSSNSSKSAEHNSMNLELKSICKLQGIVSNQSDNIQSFAKSLDETMNSSNHFGLQYQKSAILLLSILSNIDNDSMLWAFKICGWLFVNHSTLLQSCLKSGFLEFMCNCPIIFYKASFTKQDPRFTAFLDLCAITSASIIVSNKIQEFSRLLEMCEILHVSALKLSKQLTKTGTINHGTGTLAHYALEKILMTIIESICIINSNDPAFNIPITSSCIQKFLFKYRLLTNQYGFQKNLNEQLSETIKSTIGIVINTEKC 2316
BLAST of Lysosomal trafficking regulator vs. Planmine SMEST
Match: SMESG000069981.1 (SMESG000069981.1) HSP 1 Score: 4313.84 bits (11187), Expect = 0.000e+0 Identity = 2302/2302 (100.00%), Postives = 2302/2302 (100.00%), Query Frame = 1
Query: 424 MLKMDSDEKGNELDRLKAYLETEYGALMLYGIEFIIEQILIAKRNNTDSMKSSVLKIIIESELGNILATTLLSILTDMCLNTNQLIDKNFLDSITVPEFTFSQYLRQDFVRSSLFKTNIKQIRRPRPSEELSTDDNEFFPTVKIRTKRRPMKFSKYFARSDGTMNPFPFIVENQSVSEIGELCQSDMDERLYMNPISHTIETSNKVHILTSLRTAARLLYQIIQLDPSMHSDAISIYLEVLKSCCRLLNNVHSDFVSFXXXXXXXXXXXXCNIALTVSILVSEKSSSNSIMTIILGHKVTDRLLEIHQLFHEIHQDFMVLHDINKLVFYIFIIVTKNILENYSGSCRGIIHLLTGWYATGGSQIAQISLNSETSNEDFYFTLKNSKISLFSEICVLLSLLKDIPNEKRLNQIPKNSTEVFSHHSDQFNYIVTAENTDSFKDVCCYGSICYLILDNLVFLLNQDSQLKFISSRKKHIYNHILASIKTIRFCCTVDLMEFSNKLVRRLINPMPAAIKTIVISFLQRIIEISFEFYKLRFSCDCQFSSRHDVVGILQMIRNVCIPKSKEPICPLSCYNATFVELLHFIDWLGNIQDDKMKALVKENVIQPIFKRTNQYASNLHSSYCGMIGSSMFSLLPYMNYSWENDDLNLLWSACEKFPKLKRNYYKCLTITLLSTRSSPVEDSKELSMKTRIIDFLVSRVNFEILMKQMDHNSGSIKLLFEDIYIWECFRILFTYNDEFRRSMFTSNGIDCCYVMLKEIIEFISILTDENLETYKLSGFLLFESLMCLVIDGNMLKNXXXXXXXXXXXXWVQIQSSILKYFPKEESVAQSLIQSLLNCCFRHKWTVQNDLYQLRRLFLDSIVSKNISITNQGSEIDISDVGIESSFSEPXXXXXXXXXXXXXVNGSHKYDADVSSDLVNDDESELRARKKHNLRDTEGERANVFIDINTAYTNGSNMEINTDFLRLFIKIILSLPIDNYHFIGQKALESVYYSLRYIPDKNQQSFICDDFMEKMMCSIENILNSHDIPGXXXXXXXXXXXPFSCWCTAKRLRFLINLSEKNPGLKVQIIKMLIEKAELINSLQPDLSLMVPVHQNIPKSVRGWRNSNFEFYSFDEEIGDVSNYLFETKLNRPNWKGLDFDNSCENSGFSVSMWIQMDSTVEYKRRKKSGEMXXXXXXXXXXXXXXXXXXXXXXXQSIQDFIHVASIYSKDKNSSFKSQCFQIWCKPSTGTIMIRFYQRIYQTVNLDPNKPATPLPQMRESRSQIFNIFQSQTVXXXXXXXXXXXXXXXXXXXXFVLVGESMLNNVLPLNAWNFVTVSVNWKSPEVGEVFCVINGDFSYESKLIRNSHYVYQGSQSLESFFNIGQLGCPPGGSSHLKYNLGSLFIFEGAKIQTANENLSLMFLSPNWDGGSMMLNAAQRDSANTLGLVIMRILADRQVGSEFVASMLERCQNILQNNWLEKMNELITNNLVATFTCGDIPRFDVNEMCSADSEMPTLSPNYYQFSSIVSPKSETEVPVAFSSNCFSKYFIIKASVDSAIENLGGISIMIFWLAKVVESGDEVSTRYXXXXXXXXXRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQHMIYEDPTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQEPFEALEHPLPVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHPISMKDNDIDSGQYYRHLKAFTKMEVEKSTDDHNEIDGTFPEKARVCKINIQRGNHLKLNPERDITEQLSISLMGSKVSEVEKKTLQQFYVATLTDNRQDSNENNEFLDIXXXXXXXXXXXXXCPTLIDENDKNEMNSSFETSFIASNNLTDQPVISGQSESSRVHVIAGLISILENVIEVKVSDSILERCSNYDFFFEFILHLLSHTSALVRQKSLSLFRVYLYRKKSXXXXXXXXXXXXXXVSHVIHQNSTTKEILAEAISIMFGQNLFSIIMDIDWEXXXXXXXXXXXXXXXXXXXMNLELKSICKLQGIVSNQSDNIQSFAKSLDETMNSSNHFGLQYQKSAXXXXXXXXXXXXXXMLWAFKICGWLFVNHSTLLQSCLKSGFLEFMCNCPIIFYKASFTKQDPRFTAFLDLCAITSASIIVSNKIQEFSRLLEMCEILHVSALKLSKQLTKTGTINHGTGTLAHYALEKILMTIIESICIINSNDPAFNIPITSSCIQKFLFKYRLLTNQYGFQKNLNEQLSETIKSTIGIVINTEKC 7329
MLKMDSDEKGNELDRLKAYLETEYGALMLYGIEFIIEQILIAKRNNTDSMKSSVLKIIIESELGNILATTLLSILTDMCLNTNQLIDKNFLDSITVPEFTFSQYLRQDFVRSSLFKTNIKQIRRPRPSEELSTDDNEFFPTVKIRTKRRPMKFSKYFARSDGTMNPFPFIVENQSVSEIGELCQSDMDERLYMNPISHTIETSNKVHILTSLRTAARLLYQIIQLDPSMHSDAISIYLEVLKSCCRLLNNVHSDFVSFQQQLLKLADDLLCNIALTVSILVSEKSSSNSIMTIILGHKVTDRLLEIHQLFHEIHQDFMVLHDINKLVFYIFIIVTKNILENYSGSCRGIIHLLTGWYATGGSQIAQISLNSETSNEDFYFTLKNSKISLFSEICVLLSLLKDIPNEKRLNQIPKNSTEVFSHHSDQFNYIVTAENTDSFKDVCCYGSICYLILDNLVFLLNQDSQLKFISSRKKHIYNHILASIKTIRFCCTVDLMEFSNKLVRRLINPMPAAIKTIVISFLQRIIEISFEFYKLRFSCDCQFSSRHDVVGILQMIRNVCIPKSKEPICPLSCYNATFVELLHFIDWLGNIQDDKMKALVKENVIQPIFKRTNQYASNLHSSYCGMIGSSMFSLLPYMNYSWENDDLNLLWSACEKFPKLKRNYYKCLTITLLSTRSSPVEDSKELSMKTRIIDFLVSRVNFEILMKQMDHNSGSIKLLFEDIYIWECFRILFTYNDEFRRSMFTSNGIDCCYVMLKEIIEFISILTDENLETYKLSGFLLFESLMCLVIDGNMLKNIYYYEGYSYEIIWVQIQSSILKYFPKEESVAQSLIQSLLNCCFRHKWTVQNDLYQLRRLFLDSIVSKNISITNQGSEIDISDVGIESSFSEPEDDIGGDEDDSDIVNGSHKYDADVSSDLVNDDESELRARKKHNLRDTEGERANVFIDINTAYTNGSNMEINTDFLRLFIKIILSLPIDNYHFIGQKALESVYYSLRYIPDKNQQSFICDDFMEKMMCSIENILNSHDIPGLQLILLKLLTLPFSCWCTAKRLRFLINLSEKNPGLKVQIIKMLIEKAELINSLQPDLSLMVPVHQNIPKSVRGWRNSNFEFYSFDEEIGDVSNYLFETKLNRPNWKGLDFDNSCENSGFSVSMWIQMDSTVEYKRRKKSGEMKKNKKKSNKLSANANSLSKLLLLQSIQDFIHVASIYSKDKNSSFKSQCFQIWCKPSTGTIMIRFYQRIYQTVNLDPNKPATPLPQMRESRSQIFNIFQSQTVSRWDSNDSSSLLDTNSRNSSFVLVGESMLNNVLPLNAWNFVTVSVNWKSPEVGEVFCVINGDFSYESKLIRNSHYVYQGSQSLESFFNIGQLGCPPGGSSHLKYNLGSLFIFEGAKIQTANENLSLMFLSPNWDGGSMMLNAAQRDSANTLGLVIMRILADRQVGSEFVASMLERCQNILQNNWLEKMNELITNNLVATFTCGDIPRFDVNEMCSADSEMPTLSPNYYQFSSIVSPKSETEVPVAFSSNCFSKYFIIKASVDSAIENLGGISIMIFWLAKVVESGDEVSTRYLLKLILLLIRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQHMIYEDPTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQEPFEALEHPLPVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHPISMKDNDIDSGQYYRHLKAFTKMEVEKSTDDHNEIDGTFPEKARVCKINIQRGNHLKLNPERDITEQLSISLMGSKVSEVEKKTLQQFYVATLTDNRQDSNENNEFLDIESSMESSSSEPSSCPTLIDENDKNEMNSSFETSFIASNNLTDQPVISGQSESSRVHVIAGLISILENVIEVKVSDSILERCSNYDFFFEFILHLLSHTSALVRQKSLSLFRVYLYRKKSQLQQNQNQWLSINLVSHVIHQNSTTKEILAEAISIMFGQNLFSIIMDIDWENFSIFNSSSNSSKSAEHNSMNLELKSICKLQGIVSNQSDNIQSFAKSLDETMNSSNHFGLQYQKSAILLLSILSNIDNDSMLWAFKICGWLFVNHSTLLQSCLKSGFLEFMCNCPIIFYKASFTKQDPRFTAFLDLCAITSASIIVSNKIQEFSRLLEMCEILHVSALKLSKQLTKTGTINHGTGTLAHYALEKILMTIIESICIINSNDPAFNIPITSSCIQKFLFKYRLLTNQYGFQKNLNEQLSETIKSTIGIVINTEKC
Sbjct: 1 MLKMDSDEKGNELDRLKAYLETEYGALMLYGIEFIIEQILIAKRNNTDSMKSSVLKIIIESELGNILATTLLSILTDMCLNTNQLIDKNFLDSITVPEFTFSQYLRQDFVRSSLFKTNIKQIRRPRPSEELSTDDNEFFPTVKIRTKRRPMKFSKYFARSDGTMNPFPFIVENQSVSEIGELCQSDMDERLYMNPISHTIETSNKVHILTSLRTAARLLYQIIQLDPSMHSDAISIYLEVLKSCCRLLNNVHSDFVSFQQQLLKLADDLLCNIALTVSILVSEKSSSNSIMTIILGHKVTDRLLEIHQLFHEIHQDFMVLHDINKLVFYIFIIVTKNILENYSGSCRGIIHLLTGWYATGGSQIAQISLNSETSNEDFYFTLKNSKISLFSEICVLLSLLKDIPNEKRLNQIPKNSTEVFSHHSDQFNYIVTAENTDSFKDVCCYGSICYLILDNLVFLLNQDSQLKFISSRKKHIYNHILASIKTIRFCCTVDLMEFSNKLVRRLINPMPAAIKTIVISFLQRIIEISFEFYKLRFSCDCQFSSRHDVVGILQMIRNVCIPKSKEPICPLSCYNATFVELLHFIDWLGNIQDDKMKALVKENVIQPIFKRTNQYASNLHSSYCGMIGSSMFSLLPYMNYSWENDDLNLLWSACEKFPKLKRNYYKCLTITLLSTRSSPVEDSKELSMKTRIIDFLVSRVNFEILMKQMDHNSGSIKLLFEDIYIWECFRILFTYNDEFRRSMFTSNGIDCCYVMLKEIIEFISILTDENLETYKLSGFLLFESLMCLVIDGNMLKNIYYYEGYSYEIIWVQIQSSILKYFPKEESVAQSLIQSLLNCCFRHKWTVQNDLYQLRRLFLDSIVSKNISITNQGSEIDISDVGIESSFSEPEDDIGGDEDDSDIVNGSHKYDADVSSDLVNDDESELRARKKHNLRDTEGERANVFIDINTAYTNGSNMEINTDFLRLFIKIILSLPIDNYHFIGQKALESVYYSLRYIPDKNQQSFICDDFMEKMMCSIENILNSHDIPGLQLILLKLLTLPFSCWCTAKRLRFLINLSEKNPGLKVQIIKMLIEKAELINSLQPDLSLMVPVHQNIPKSVRGWRNSNFEFYSFDEEIGDVSNYLFETKLNRPNWKGLDFDNSCENSGFSVSMWIQMDSTVEYKRRKKSGEMKKNKKKSNKLSANANSLSKLLLLQSIQDFIHVASIYSKDKNSSFKSQCFQIWCKPSTGTIMIRFYQRIYQTVNLDPNKPATPLPQMRESRSQIFNIFQSQTVSRWDSNDSSSLLDTNSRNSSFVLVGESMLNNVLPLNAWNFVTVSVNWKSPEVGEVFCVINGDFSYESKLIRNSHYVYQGSQSLESFFNIGQLGCPPGGSSHLKYNLGSLFIFEGAKIQTANENLSLMFLSPNWDGGSMMLNAAQRDSANTLGLVIMRILADRQVGSEFVASMLERCQNILQNNWLEKMNELITNNLVATFTCGDIPRFDVNEMCSADSEMPTLSPNYYQFSSIVSPKSETEVPVAFSSNCFSKYFIIKASVDSAIENLGGISIMIFWLAKVVESGDEVSTRYLLKLILLLIRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQHMIYEDPTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQEPFEALEHPLPVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHPISMKDNDIDSGQYYRHLKAFTKMEVEKSTDDHNEIDGTFPEKARVCKINIQRGNHLKLNPERDITEQLSISLMGSKVSEVEKKTLQQFYVATLTDNRQDSNENNEFLDIESSMESSSSEPSSCPTLIDENDKNEMNSSFETSFIASNNLTDQPVISGQSESSRVHVIAGLISILENVIEVKVSDSILERCSNYDFFFEFILHLLSHTSALVRQKSLSLFRVYLYRKKSQLQQNQNQWLSINLVSHVIHQNSTTKEILAEAISIMFGQNLFSIIMDIDWENFSIFNSSSNSSKSAEHNSMNLELKSICKLQGIVSNQSDNIQSFAKSLDETMNSSNHFGLQYQKSAILLLSILSNIDNDSMLWAFKICGWLFVNHSTLLQSCLKSGFLEFMCNCPIIFYKASFTKQDPRFTAFLDLCAITSASIIVSNKIQEFSRLLEMCEILHVSALKLSKQLTKTGTINHGTGTLAHYALEKILMTIIESICIINSNDPAFNIPITSSCIQKFLFKYRLLTNQYGFQKNLNEQLSETIKSTIGIVINTEKC 2302
BLAST of Lysosomal trafficking regulator vs. Planmine SMEST
Match: SMESG000069981.1 (SMESG000069981.1) HSP 1 Score: 4308.06 bits (11172), Expect = 0.000e+0 Identity = 2299/2299 (100.00%), Postives = 2299/2299 (100.00%), Query Frame = 1
Query: 433 MDSDEKGNELDRLKAYLETEYGALMLYGIEFIIEQILIAKRNNTDSMKSSVLKIIIESELGNILATTLLSILTDMCLNTNQLIDKNFLDSITVPEFTFSQYLRQDFVRSSLFKTNIKQIRRPRPSEELSTDDNEFFPTVKIRTKRRPMKFSKYFARSDGTMNPFPFIVENQSVSEIGELCQSDMDERLYMNPISHTIETSNKVHILTSLRTAARLLYQIIQLDPSMHSDAISIYLEVLKSCCRLLNNVHSDFVSFXXXXXXXXXXXXCNIALTVSILVSEKSSSNSIMTIILGHKVTDRLLEIHQLFHEIHQDFMVLHDINKLVFYIFIIVTKNILENYSGSCRGIIHLLTGWYATGGSQIAQISLNSETSNEDFYFTLKNSKISLFSEICVLLSLLKDIPNEKRLNQIPKNSTEVFSHHSDQFNYIVTAENTDSFKDVCCYGSICYLILDNLVFLLNQDSQLKFISSRKKHIYNHILASIKTIRFCCTVDLMEFSNKLVRRLINPMPAAIKTIVISFLQRIIEISFEFYKLRFSCDCQFSSRHDVVGILQMIRNVCIPKSKEPICPLSCYNATFVELLHFIDWLGNIQDDKMKALVKENVIQPIFKRTNQYASNLHSSYCGMIGSSMFSLLPYMNYSWENDDLNLLWSACEKFPKLKRNYYKCLTITLLSTRSSPVEDSKELSMKTRIIDFLVSRVNFEILMKQMDHNSGSIKLLFEDIYIWECFRILFTYNDEFRRSMFTSNGIDCCYVMLKEIIEFISILTDENLETYKLSGFLLFESLMCLVIDGNMLKNXXXXXXXXXXXXWVQIQSSILKYFPKEESVAQSLIQSLLNCCFRHKWTVQNDLYQLRRLFLDSIVSKNISITNQGSEIDISDVGIESSFSEPXXXXXXXXXXXXXVNGSHKYDADVSSDLVNDDESELRARKKHNLRDTEGERANVFIDINTAYTNGSNMEINTDFLRLFIKIILSLPIDNYHFIGQKALESVYYSLRYIPDKNQQSFICDDFMEKMMCSIENILNSHDIPGXXXXXXXXXXXPFSCWCTAKRLRFLINLSEKNPGLKVQIIKMLIEKAELINSLQPDLSLMVPVHQNIPKSVRGWRNSNFEFYSFDEEIGDVSNYLFETKLNRPNWKGLDFDNSCENSGFSVSMWIQMDSTVEYKRRKKSGEMXXXXXXXXXXXXXXXXXXXXXXXQSIQDFIHVASIYSKDKNSSFKSQCFQIWCKPSTGTIMIRFYQRIYQTVNLDPNKPATPLPQMRESRSQIFNIFQSQTVXXXXXXXXXXXXXXXXXXXXFVLVGESMLNNVLPLNAWNFVTVSVNWKSPEVGEVFCVINGDFSYESKLIRNSHYVYQGSQSLESFFNIGQLGCPPGGSSHLKYNLGSLFIFEGAKIQTANENLSLMFLSPNWDGGSMMLNAAQRDSANTLGLVIMRILADRQVGSEFVASMLERCQNILQNNWLEKMNELITNNLVATFTCGDIPRFDVNEMCSADSEMPTLSPNYYQFSSIVSPKSETEVPVAFSSNCFSKYFIIKASVDSAIENLGGISIMIFWLAKVVESGDEVSTRYXXXXXXXXXRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQHMIYEDPTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQEPFEALEHPLPVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHPISMKDNDIDSGQYYRHLKAFTKMEVEKSTDDHNEIDGTFPEKARVCKINIQRGNHLKLNPERDITEQLSISLMGSKVSEVEKKTLQQFYVATLTDNRQDSNENNEFLDIXXXXXXXXXXXXXCPTLIDENDKNEMNSSFETSFIASNNLTDQPVISGQSESSRVHVIAGLISILENVIEVKVSDSILERCSNYDFFFEFILHLLSHTSALVRQKSLSLFRVYLYRKKSXXXXXXXXXXXXXXVSHVIHQNSTTKEILAEAISIMFGQNLFSIIMDIDWEXXXXXXXXXXXXXXXXXXXMNLELKSICKLQGIVSNQSDNIQSFAKSLDETMNSSNHFGLQYQKSAXXXXXXXXXXXXXXMLWAFKICGWLFVNHSTLLQSCLKSGFLEFMCNCPIIFYKASFTKQDPRFTAFLDLCAITSASIIVSNKIQEFSRLLEMCEILHVSALKLSKQLTKTGTINHGTGTLAHYALEKILMTIIESICIINSNDPAFNIPITSSCIQKFLFKYRLLTNQYGFQKNLNEQLSETIKSTIGIVINTEKC 7329
MDSDEKGNELDRLKAYLETEYGALMLYGIEFIIEQILIAKRNNTDSMKSSVLKIIIESELGNILATTLLSILTDMCLNTNQLIDKNFLDSITVPEFTFSQYLRQDFVRSSLFKTNIKQIRRPRPSEELSTDDNEFFPTVKIRTKRRPMKFSKYFARSDGTMNPFPFIVENQSVSEIGELCQSDMDERLYMNPISHTIETSNKVHILTSLRTAARLLYQIIQLDPSMHSDAISIYLEVLKSCCRLLNNVHSDFVSFQQQLLKLADDLLCNIALTVSILVSEKSSSNSIMTIILGHKVTDRLLEIHQLFHEIHQDFMVLHDINKLVFYIFIIVTKNILENYSGSCRGIIHLLTGWYATGGSQIAQISLNSETSNEDFYFTLKNSKISLFSEICVLLSLLKDIPNEKRLNQIPKNSTEVFSHHSDQFNYIVTAENTDSFKDVCCYGSICYLILDNLVFLLNQDSQLKFISSRKKHIYNHILASIKTIRFCCTVDLMEFSNKLVRRLINPMPAAIKTIVISFLQRIIEISFEFYKLRFSCDCQFSSRHDVVGILQMIRNVCIPKSKEPICPLSCYNATFVELLHFIDWLGNIQDDKMKALVKENVIQPIFKRTNQYASNLHSSYCGMIGSSMFSLLPYMNYSWENDDLNLLWSACEKFPKLKRNYYKCLTITLLSTRSSPVEDSKELSMKTRIIDFLVSRVNFEILMKQMDHNSGSIKLLFEDIYIWECFRILFTYNDEFRRSMFTSNGIDCCYVMLKEIIEFISILTDENLETYKLSGFLLFESLMCLVIDGNMLKNIYYYEGYSYEIIWVQIQSSILKYFPKEESVAQSLIQSLLNCCFRHKWTVQNDLYQLRRLFLDSIVSKNISITNQGSEIDISDVGIESSFSEPEDDIGGDEDDSDIVNGSHKYDADVSSDLVNDDESELRARKKHNLRDTEGERANVFIDINTAYTNGSNMEINTDFLRLFIKIILSLPIDNYHFIGQKALESVYYSLRYIPDKNQQSFICDDFMEKMMCSIENILNSHDIPGLQLILLKLLTLPFSCWCTAKRLRFLINLSEKNPGLKVQIIKMLIEKAELINSLQPDLSLMVPVHQNIPKSVRGWRNSNFEFYSFDEEIGDVSNYLFETKLNRPNWKGLDFDNSCENSGFSVSMWIQMDSTVEYKRRKKSGEMKKNKKKSNKLSANANSLSKLLLLQSIQDFIHVASIYSKDKNSSFKSQCFQIWCKPSTGTIMIRFYQRIYQTVNLDPNKPATPLPQMRESRSQIFNIFQSQTVSRWDSNDSSSLLDTNSRNSSFVLVGESMLNNVLPLNAWNFVTVSVNWKSPEVGEVFCVINGDFSYESKLIRNSHYVYQGSQSLESFFNIGQLGCPPGGSSHLKYNLGSLFIFEGAKIQTANENLSLMFLSPNWDGGSMMLNAAQRDSANTLGLVIMRILADRQVGSEFVASMLERCQNILQNNWLEKMNELITNNLVATFTCGDIPRFDVNEMCSADSEMPTLSPNYYQFSSIVSPKSETEVPVAFSSNCFSKYFIIKASVDSAIENLGGISIMIFWLAKVVESGDEVSTRYLLKLILLLIRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQHMIYEDPTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQEPFEALEHPLPVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHPISMKDNDIDSGQYYRHLKAFTKMEVEKSTDDHNEIDGTFPEKARVCKINIQRGNHLKLNPERDITEQLSISLMGSKVSEVEKKTLQQFYVATLTDNRQDSNENNEFLDIESSMESSSSEPSSCPTLIDENDKNEMNSSFETSFIASNNLTDQPVISGQSESSRVHVIAGLISILENVIEVKVSDSILERCSNYDFFFEFILHLLSHTSALVRQKSLSLFRVYLYRKKSQLQQNQNQWLSINLVSHVIHQNSTTKEILAEAISIMFGQNLFSIIMDIDWENFSIFNSSSNSSKSAEHNSMNLELKSICKLQGIVSNQSDNIQSFAKSLDETMNSSNHFGLQYQKSAILLLSILSNIDNDSMLWAFKICGWLFVNHSTLLQSCLKSGFLEFMCNCPIIFYKASFTKQDPRFTAFLDLCAITSASIIVSNKIQEFSRLLEMCEILHVSALKLSKQLTKTGTINHGTGTLAHYALEKILMTIIESICIINSNDPAFNIPITSSCIQKFLFKYRLLTNQYGFQKNLNEQLSETIKSTIGIVINTEKC
Sbjct: 1 MDSDEKGNELDRLKAYLETEYGALMLYGIEFIIEQILIAKRNNTDSMKSSVLKIIIESELGNILATTLLSILTDMCLNTNQLIDKNFLDSITVPEFTFSQYLRQDFVRSSLFKTNIKQIRRPRPSEELSTDDNEFFPTVKIRTKRRPMKFSKYFARSDGTMNPFPFIVENQSVSEIGELCQSDMDERLYMNPISHTIETSNKVHILTSLRTAARLLYQIIQLDPSMHSDAISIYLEVLKSCCRLLNNVHSDFVSFQQQLLKLADDLLCNIALTVSILVSEKSSSNSIMTIILGHKVTDRLLEIHQLFHEIHQDFMVLHDINKLVFYIFIIVTKNILENYSGSCRGIIHLLTGWYATGGSQIAQISLNSETSNEDFYFTLKNSKISLFSEICVLLSLLKDIPNEKRLNQIPKNSTEVFSHHSDQFNYIVTAENTDSFKDVCCYGSICYLILDNLVFLLNQDSQLKFISSRKKHIYNHILASIKTIRFCCTVDLMEFSNKLVRRLINPMPAAIKTIVISFLQRIIEISFEFYKLRFSCDCQFSSRHDVVGILQMIRNVCIPKSKEPICPLSCYNATFVELLHFIDWLGNIQDDKMKALVKENVIQPIFKRTNQYASNLHSSYCGMIGSSMFSLLPYMNYSWENDDLNLLWSACEKFPKLKRNYYKCLTITLLSTRSSPVEDSKELSMKTRIIDFLVSRVNFEILMKQMDHNSGSIKLLFEDIYIWECFRILFTYNDEFRRSMFTSNGIDCCYVMLKEIIEFISILTDENLETYKLSGFLLFESLMCLVIDGNMLKNIYYYEGYSYEIIWVQIQSSILKYFPKEESVAQSLIQSLLNCCFRHKWTVQNDLYQLRRLFLDSIVSKNISITNQGSEIDISDVGIESSFSEPEDDIGGDEDDSDIVNGSHKYDADVSSDLVNDDESELRARKKHNLRDTEGERANVFIDINTAYTNGSNMEINTDFLRLFIKIILSLPIDNYHFIGQKALESVYYSLRYIPDKNQQSFICDDFMEKMMCSIENILNSHDIPGLQLILLKLLTLPFSCWCTAKRLRFLINLSEKNPGLKVQIIKMLIEKAELINSLQPDLSLMVPVHQNIPKSVRGWRNSNFEFYSFDEEIGDVSNYLFETKLNRPNWKGLDFDNSCENSGFSVSMWIQMDSTVEYKRRKKSGEMKKNKKKSNKLSANANSLSKLLLLQSIQDFIHVASIYSKDKNSSFKSQCFQIWCKPSTGTIMIRFYQRIYQTVNLDPNKPATPLPQMRESRSQIFNIFQSQTVSRWDSNDSSSLLDTNSRNSSFVLVGESMLNNVLPLNAWNFVTVSVNWKSPEVGEVFCVINGDFSYESKLIRNSHYVYQGSQSLESFFNIGQLGCPPGGSSHLKYNLGSLFIFEGAKIQTANENLSLMFLSPNWDGGSMMLNAAQRDSANTLGLVIMRILADRQVGSEFVASMLERCQNILQNNWLEKMNELITNNLVATFTCGDIPRFDVNEMCSADSEMPTLSPNYYQFSSIVSPKSETEVPVAFSSNCFSKYFIIKASVDSAIENLGGISIMIFWLAKVVESGDEVSTRYLLKLILLLIRKSVFLAHQNIEEKGYSVLLQLFKSFKMTLGFDIISDLVQHMIYEDPTKSKLSLPCNSRLCRDPQILHELLMHWKILATSKLNASKGEISMTECQALNLDKYLLEQINSLLNEDNIYSIINCGSLGTVGLLSPLLMSCQEPFEALEHPLPVGICKILIQIINNLIPTPVDISIVTKLCNTILQLHPISMKDNDIDSGQYYRHLKAFTKMEVEKSTDDHNEIDGTFPEKARVCKINIQRGNHLKLNPERDITEQLSISLMGSKVSEVEKKTLQQFYVATLTDNRQDSNENNEFLDIESSMESSSSEPSSCPTLIDENDKNEMNSSFETSFIASNNLTDQPVISGQSESSRVHVIAGLISILENVIEVKVSDSILERCSNYDFFFEFILHLLSHTSALVRQKSLSLFRVYLYRKKSQLQQNQNQWLSINLVSHVIHQNSTTKEILAEAISIMFGQNLFSIIMDIDWENFSIFNSSSNSSKSAEHNSMNLELKSICKLQGIVSNQSDNIQSFAKSLDETMNSSNHFGLQYQKSAILLLSILSNIDNDSMLWAFKICGWLFVNHSTLLQSCLKSGFLEFMCNCPIIFYKASFTKQDPRFTAFLDLCAITSASIIVSNKIQEFSRLLEMCEILHVSALKLSKQLTKTGTINHGTGTLAHYALEKILMTIIESICIINSNDPAFNIPITSSCIQKFLFKYRLLTNQYGFQKNLNEQLSETIKSTIGIVINTEKC 2299
BLAST of Lysosomal trafficking regulator vs. Planmine SMEST
Match: SMESG000069985.1 (SMESG000069985.1) HSP 1 Score: 2281.52 bits (5911), Expect = 0.000e+0 Identity = 1172/1183 (99.07%), Postives = 1176/1183 (99.41%), Query Frame = 1
Query: 7390 MILISNCLACNQTPDEFSVFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFAISPDFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMTSKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQXXXXXXXXXXXXIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQYISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESGHLQVLQSNRLDLSPRQSIYFWL*LFFSKCFSLINFV 10938
MILISNCLACNQTPDEFSVFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYCLLGNSSGSLCLILNVKQILEHVKRSGNQTEEFIKSLSQLLFAISPDFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMASSWHLSTSSLSCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFINEIHKKKENIIGNLFLLPTSKMTSKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLGSFLVSVGSGQGVVKSIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQSSKKFNFSSSGNIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQYISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESGHLQVLQSNRLDLSPRQSIYFW F+ C SL++ +
Sbjct: 1 MILISNCLACNQTPDEFSVFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYCLLGNSSGSLCLILNVKQILEHVKRSGNQTEEFIKSLSQLLFAISPDFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMASSWHLSTSSLSCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFINEIHKKKENIIGNLFLLPTSKMTSKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLGSFLVSVGSGQGVVKSIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQSSKKFNFSSSGNIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQYISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESGHLQVLQSNRLDLSPRQSIYFWT-QFYLLCKSLVSTI 1182
BLAST of Lysosomal trafficking regulator vs. Planmine SMEST
Match: SMESG000069985.1 (SMESG000069985.1) HSP 1 Score: 2273.82 bits (5891), Expect = 0.000e+0 Identity = 1169/1169 (100.00%), Postives = 1169/1169 (100.00%), Query Frame = 1
Query: 7390 MILISNCLACNQTPDEFSVFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYXXXXXXXXXXXXXXXVKQILEHVKRSGNQTEEFIKSLSQLLFAISPDFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMAXXXXXXXXXXXCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFXXXXXXXXXXXXGNLFLLPTSKMTSKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLXXXXXXXXXXXXXXXXIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQXXXXXXXXXXXXIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQYISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESGHLQVLQSNRLDLSPRQSIYFWL 10896
MILISNCLACNQTPDEFSVFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYCLLGNSSGSLCLILNVKQILEHVKRSGNQTEEFIKSLSQLLFAISPDFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMASSWHLSTSSLSCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFINEIHKKKENIIGNLFLLPTSKMTSKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLGSFLVSVGSGQGVVKSIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQSSKKFNFSSSGNIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQYISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESGHLQVLQSNRLDLSPRQSIYFWL
Sbjct: 1 MILISNCLACNQTPDEFSVFLGCKEAIKSHLGDLLICLTQSKLSLHLRLEAVKCVFRFHNFDRVVRYCLLGNSSGSLCLILNVKQILEHVKRSGNQTEEFIKSLSQLLFAISPDFSVEDLNEDNRNLWVKENEFKLNAYKKKFKSKLDNWNQNTDRRFNEVSIQMKNSYNNYRTYARKNLQHEFISNIKAQRASEFYRRLSWKILIATFTQEKEIWDDSNKKSQIYRLDPIEGPSRIRRRMIKTTHKINDKYFNPTSPARNVQDKSSSGESLTFLFESTYQVDKIVYENPIDCQLLKCIEDIQISCPCILVCESGHFKGEFFVGKWRIGFLEDRVNNLYSEYDELPNYLKDFGFINWHLNDIEWVLRRRFKLRDYALEMIMKDGRNCLIAMNSTLERDRILSFIENILPPNANRKPRLIDIQREWAEGKMSNFDYLTFLNTAAGRSYNDIMQYPVFPFILTEYTSSTLDLTKESTYRDLSKPISIQNGPLREKVINCFTEKADEYQRQLRMMQTSNNIDEMSVWAVPPYHYSSLYSNSATVLYYMIRIPPFTQKFIQFQDGEFDRPDRMFHTMASSWHLSTSSLSCMKEIIPEFFYLPELFVNSQDFNFGERLNGTKVDDVILPEWSSGDARLFCLIHRASLESPYVSNQLNYWVDLVFGFKQTGKAALEAINLFHPYTYYKAICPDEITEEIRRSAVEQMIENYGQIPKQLFINKSFPAKKINWRNIKNTAPRNIQHSFSSDKGYQDTDQMKDSIESNCESIKTLSKDRKCLTVLNSVIGIEWGDWVGSPNNSQTFINEIHKKKENIIGNLFLLPTSKMTSKRPLQMLVIQELSSVLMLPPTEEGSQVFIKFSLATNKRRVQVDSMTYGNPSNNEVQLENLGSFLVSVGSGQGVVKSIAVSQRSGRVFFGMESGLITVYQGDMFKYSQTRSFVDNLNHHRKTLLGHKTEIIFLQLCDSFAVLASCDIQTNVAIWDSQTLELLHYIDWQSVKYIQSSKKFNFSSSGNIAELLHNEISQIQSESMTKVSAMSFSETLGDMVISRLMKQKTVNSQYISNVSLFTINGKHVDSIMLSGTVVSLSYTKLTEGCNVNAIAAITDEGRLTVMSSWNLQVVWKVKIPQLYQSDPIKAIQYTHSGRELYVLNESGHLQVLQSNRLDLSPRQSIYFWL 1169 The following BLAST results are available for this feature:
BLAST of Lysosomal trafficking regulator vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Lysosomal trafficking regulator vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Lysosomal trafficking regulator vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30007567 ID=SMED30007567|Name=Lysosomal trafficking regulator|organism=Schmidtea mediterranea sexual|type=transcript|length=10951bpback to top protein sequence of SMED30007567-orf-1 >SMED30007567-orf-1 ID=SMED30007567-orf-1|Name=SMED30007567-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=3568bp MMEPLLNPLFSSNKENTRPCLINWKKSENLLIFLRSLYIKSSKQRNQTRSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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