ATP-binding cassette sub-family A member 1

Overview


Name	ATP-binding cassette sub-family A member 1
Smed ID	SMED30007539
Length (bp)	2554

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30007539

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30007539	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30007539	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30007539	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30007539	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30007539	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30007539	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30007539	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30007539	SMESG000032896.1 SMESG000032891.1 SMESG000029537.1 SMESG000029534.1	Contig35762	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30007539	SMESG000032896.1 SMESG000032891.1 SMESG000029537.1 SMESG000029534.1	Contig35762	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
reproductive organ	SMED30007539	SMESG000032891.1 SMESG000029537.1	Contig8654	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30007539	SMESG000032891.1 SMESG000029537.1	Contig8654	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
epidermis	SMED30007539	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

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Homology

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:29])

HSP 1 Score: 375.17 bits (962), Expect = 1.296e-110
Identity = 292/929 (31.43%), Postives = 472/929 (50.81%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWS--PIP--------NGNIPL--ISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNF-----QRLSRKI------FGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQ-----PQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYF-------YNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 ++  ++++  +  S++G                +   I+ H+ +A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG+S+T+LEE+F++VA++ + ++ ET +  L P   NR A +GD ++   PF   D  D N      +S    L+S    +    ++G+ L +QQ + L  KR   A+R++KG FA+++LP + + + +    +V P    P++E+ PW+            +  +   ++       G    +N LT         D G  G RCM  +    T  +   E    +W+  P+P        NGN  +   SP C C++   +    +C     G P    R   ++D L +LTG NISDYL+K +     + L  KI      +GG+   + N  A         P    + D++ Q +      ++    RFL     F      T N  ++W N+KG+ ++ ++ N+++N +LR+ ++  +N  +YGI+  N+P+  ++ ++S+   +   ++V ++I VI A+SF+ ASFV+FLI ER+S +K  QF+SG+ P +YW+SNF+WD+  Y++P  ++IIIFI F  +SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   N   L  INDILK VFLIFP F LGRG++D+  N         +  N  V    + L WD+ G  LF++    + ++++ ++I+     R      K S L      N ED DV  ER+R+      +D+L +  LTKIY                     + R+ AV+ +C G+  GECFGLLGVNGAGK++TF
Sbjct: 1098 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVSEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEE-SGVDAETSDGTL-PARRNRRA-FGDKQSCLRPFTEDDAADPNDSDIDPESRETDLLSGMDGKGSYQVKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWM------------YNEQYTFVSNDAPEDTGTLELLNALT--------KDPG-FGTRCMEGNPIPDTPCQAGEE----EWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSSDKIKKMLPVCPPGAGGLP-PPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNTQAL--------PPSQEVNDAIKQMKKHLKLAKDSSADRFLNSLGRFMT-GLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTDN--KLNNINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFV----SPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFFIRPRPVNAKLSPL------NDEDEDVRRERQRILDGGGQNDILEIKELTKIY--------------------RRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTF 1956

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Match: ABCA7 (ATP binding cassette subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:37])

HSP 1 Score: 343.969 bits (881), Expect = 6.552e-100
Identity = 274/915 (29.95%), Postives = 453/915 (49.51%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-------------------NFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAK---INEETKNEKL--------IPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGN-IP-LISPECDCNTTGYQ-ICND--PRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRK-----------IFGGYQFLLPNDFAQSSKLIAQS---------PTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNS--NSIVKHEYNA-LQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRN-----TEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DR+A+++ G+L CCGS +FL+R  G GY L LVK                   +   +K+N  +G      +LL  ++  +P A++  E   +   VLP   ++   F+ LF  LD  +  L    YG+SDTSLEE+F++V ++ A    + + +  + L        +   L        +EN EP     + +Q +  D         R    ++G+ L +QQ+  L +KRF  A+R+++G+FA+++LP L + L +    +V P    PA+ +SP             T Y    Q++F   +  G+      L   L+        E+G+    P +  S+H    PE        + +GN  P   SP C C+  G + +  D    +GGPP    +  S + + NLTG N+SD+L+K + RL R+            +GG+     +    S + + +S         P   G  D             R LK    + + S    +  +IW N+KG+ SM A+ N  SN +LR+ +        + I+  N+P+  ++ ++S+   +   ++V ++I V+ A+SF+ ASF + LI+ER++ +K  Q + G++P +YW+ NFLWD+  Y++P  I+++IF+AF  ++Y+   N  A +LLL+ YG +I P MYP SFF S PSTA+VVL   NL +G   +++TF+L++   + + L+E++ ILK+VFLIFP F LGRG++D+  N         +   ++ + L+W++ G+ L +           ++I     +   +  + ++  L +  +R+      ED DV  ERER+       DVL + NLTK+Y            +G+        R  AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1005 GDRVAVVAGGRLCCCGSPLFLRRHLGSGYYLTLVKARLPLTTNEKADTDMEGSVDTRQEKKNGSQGSRVGTPQLLALVQHWVPGARLVEELPHELVLVLPYTGAHDGSFATLFRELDTRLAELRLTGYGISDTSLEEIFLKVVEECAADTDMEDGSCGQHLCTGIAGLDVTLRLKMPPQETALENGEPAGSAPETDQGSGPDA------VGR----VQGWALTRQQLQALLLKRFLLARRSRRGLFAQIVLPALFVGLALVFSLIVPPFGHYPALRLSP-------------TMYGA--QVSFFSEDAPGDPGRARLLEALLQ--------EAGLE--EPPVQHSSHRFSAPEVPAEVAKVLASGNWTPESPSPACQCSRPGARRLLPDCPAAAGGPPPPQAVTGSGEVVQNLTGRNLSDFLVKTYPRLVRQGLKTKKWVNEVRYGGFSLGGRDPGLPSGQELGRSVEELWALLSPLPGGALD-------------RVLKNLTAWAH-SLDAQDSLKIWFNNKGWHSMVAFVNRASNAILRAHLPPGPARHAHSITTLNHPLNLTKEQLSEGALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLMGGLSPTLYWLGNFLWDMCNYLVPACIVVLIFLAFQQRAYVAPANLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINGSMATFVLELF--SDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMADAFERLGDRQFQSPLRWEVVGKNLLA-----------MVIQGPLFLLFTLLLQHRSQLLPQPRVRSLPLLGEEDEDVARERERVVQGATQGDVLVLRNLTKVY------------RGQ--------RMPAVDRLCLGIPPGECFGLLGVNGAGKTSTF 1837

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Match: ABCA4 (ATP binding cassette subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:34])

HSP 1 Score: 333.954 bits (855), Expect = 1.497e-96
Identity = 269/919 (29.27%), Postives = 441/919 (47.99%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILV---KNFNAQKENFR-------KGISNS---------------GD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHK--------------LLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKE-NQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYR--STHYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSR-----------KIFGGYQF--LLPNDFAQSSKLIAQSPTWDGIRDSVNQ--SQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYN---SNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESG-IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAII+QG+L C G+ +FLK  FG G  L LV   KN  +Q++          KG S +               GD  +L+  +  H+P+AK+      +  F+LP  +     ++ LF  L+E + +L   S+G+SDT LEE+F++V +D           +   +N+N          + P L   +   Q   D ++ S      H               L  G  L+ Q +  L +KRF +  R+ K   A+++LP   + L + L  ++ P    PA+ + PW+   +    +++    ++   L   + N+ G  N    L +    EY          C N + ++  S        ++  KW+ +        SP C C+T    T    C +  +GG P   R   S++ L +LT  NISD+L+K +  L R           + +GG      LP        L+        I +      ++  + E   FLK+ +        T +  ++W N+KG+ ++ ++ N+  N +LR+ +   ++   YGI+V + P+  ++ ++S+   L   ++  +AI VI ++SF+ ASFV++LI ER++ SK  QF+SG++P  YWV+NFLWDIM Y +   +++ IFI F  ++Y   +N  A + LL+ YG A+IP MYP SF    PSTA+V L+  NL +G  ++  TFIL++ E N   L+  N +L+K+ ++FP F LGRG++DL  +       +    +H  N   WD+ G+ LF++    + ++++ ++++    +++ I    K   +        ED DV  ER+R+ +     D+LR+  LTKIY                          AV+ LC GVR GECFGLLGVNGAGKTTTF
Sbjct: 1127 GDRIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTCSCSSKGFSTTCPAHVDDLTPEQVLDGDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGPLFAGGAQQKRENVN---------PRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPECPGPQLNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPALTLHPWIYGQQYTFFSMDEPGSEQFTVLADVLLNKPGFGNRC--LKEGWLPEYP---------CGNSTPWKTPSVSPNITQLFQKQKWTQVNP------SPSCRCSTREKLTMLPECPE-GAGGLPPPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPVVPITGEALVGFLSDLGRIMNVSGGPITREASKEIPDFLKHLE--------TEDNIKVWFNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITVISQPLNLTKEQLSEITVLTTSVDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSVSAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINSSAITFILELFENNRTLLR-FNAVLRKLLIVFPHFCLGRGLIDLALSQAVTDVYARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTLLVQRHFFLSQWIAEPTKEPIVD-------EDDDVAEERQRIITGGNKTDILRLHELTKIY--------------------PGTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTF 1982

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Match: ABCA4 (ATP binding cassette subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:34])

HSP 1 Score: 303.523 bits (776), Expect = 5.291e-88
Identity = 240/837 (28.67%), Postives = 403/837 (48.15%), Query Frame = 2

Query:  167 LQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHK--------------LLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKE-NQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYR--STHYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSR-----------KIFGGYQF--LLPNDFAQSSKLIAQSPTWDGIRDSVNQ--SQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYN---SNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESG-IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            +  +  H+P+AK+      +  F+LP  +     ++ LF  L+E + +L   S+G+SDT LEE+F++V +D           +   +N+N          + P L   +   Q   D ++ S      H               L  G  L+ Q +  L +KRF +  R+ K   A+++LP   + L + L  ++ P    PA+ + PW+   +    +++    ++   L   + N+ G  N    L +    EY          C N + ++  S        ++  KW+ +        SP C C+T    T    C +  +GG P   R   S++ L +LT  NISD+L+K +  L R           + +GG      LP        L+        I +      ++  + E   FLK+ +        T +  ++W N+KG+ ++ ++ N+  N +LR+ +   ++   YGI+V + P+  ++ ++S+   L   ++  +AI VI ++SF+ ASFV++LI ER++ SK  QF+SG++P  YWV+NFLWDIM Y +   +++ IFI F  ++Y   +N  A + LL+ YG A+IP MYP SF    PSTA+V L+  NL +G  ++  TFIL++ E N   L+  N +L+K+ ++FP F LGRG++DL  +       +    +H  N   WD+ G+ LF++    + ++++ ++++    +++ I    K   +        ED DV  ER+R+ +     D+LR+  LTKIY                          AV+ LC GVR GECFGLLGVNGAGKTTTF
Sbjct:    1 MDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGPLFAGGAQQKRENVN---------PRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPECPGPQLNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPALTLHPWIYGQQYTFFSMDEPGSEQFTVLADVLLNKPGFGNRC--LKEGWLPEYP---------CGNSTPWKTPSVSPNITQLFQKQKWTQVNP------SPSCRCSTREKLTMLPECPE-GAGGLPPPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPVVPITGEALVGFLSDLGRIMNVSGGPITREASKEIPDFLKHLE--------TEDNIKVWFNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITVISQPLNLTKEQLSEITVLTTSVDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSVSAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINSSAITFILELFENNRTLLR-FNAVLRKLLIVFPHFCLGRGLIDLALSQAVTDVYARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTLLVQRHFFLSQWIAEPTKEPIVD-------EDDDVAEERQRIITGGNKTDILRLHELTKIY--------------------PGTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTF 774

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Match: ABCA2 (ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32])

HSP 1 Score: 276.944 bits (707), Expect = 2.465e-77
Identity = 175/541 (32.35%), Postives = 278/541 (51.39%), Query Frame = 2

Query:  965 PEYKNNKWSPIPNGNIPLISPE---CDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQ-NSWNYGISVTNYPIADSETKISQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNAL----QWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNT---EDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            P      W+  P+  +P +  E   C C+  G         GG P   R++T  D L ++TG+N+S+YLL    R     +G   F           ++   P   G R       P  +  +   +  Q F+              N+KGY SMP Y N L+N +LR+ +  S+ N   YGI+VTN+P+  +   +S    L   +V +AI++I+A+SF+ ASFV+FL+ E+ + +K  QFVSG NP +YW++N++WD++ Y++P    +II   FD  +Y    N  A + L + YG +I P MYP SF+   PS+A+V L   NL +G   T++TF+L + E + + LK +N  LK  FLIFP +NLG G+M++ +N + N       +++ +    +WDI    L ++    +  +++ I+ +   + R           +R+ +      +D DV  ER+R+      +D++++ NLTK+Y                   +   R +AV+ LC GVR GECFGLLGVNGAGKT+TF
Sbjct: 1618 PTAGPEMWTSAPS--LPRLVREPVRCTCSAQGTGFSCPSSVGGHPPQMRVVTG-DILTDITGHNVSEYLLFTSDRFRLHRYGAITF---------GNVLKSIPASFGTR------APPMVRKIAVRRAAQVFY--------------NNKGYHSMPTYLNSLNNAILRANLPKSKGNPAAYGITVTNHPMNKTSASLSLDYLLQGTDVVIAIFIIVAMSFVPASFVVFLVAEKSTKAKHLQFVSGCNPIIYWLANYVWDMLNYLVPATCCVIILFVFDLPAYTSPTNFPAVLSLFLLYGWSITPIMYPASFWFEVPSSAYVFLIVINLFIGITATVATFLLQLFEHDKD-LKVVNSYLKSCFLIFPNYNLGHGLMEMAYNEYINEYYAKIGQFDKMKSPFEWDIVTRGLVAMAVEGVVGFLLTIMCQYNFLRRP----------QRMPVSTKPVEDDVDVASERQRVLRGDADNDMVKIENLTKVYKS-----------------RKIGRILAVDRLCLGVRPGECFGLLGVNGAGKTSTF 2098

HSP 2 Score: 116.316 bits (290), Expect = 1.094e-25
Identity = 91/308 (29.55%), Postives = 147/308 (47.73%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGD-----------KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD-------PAKINEETKNEKLIP------------DNLNRIA----------------------------VYGDIENQEPFLD-LEDLNQQAFVDKSLISLN-FNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISP 748
            DRIAIIS GKL+CCGS +FLK  +GDGYRL LVK           G+++S             ++ QFI+ H+    + ++T T+ S++LP   +    F  LF +L+  +D L+  S+GL DT+LEEVF++V+++        A + E  K+  ++P             NL R +                            VYGD     P  D  +D +  +  +    +L+   +  + L G  L  +Q  GL +KRFH A+RN K +F++++LP   + + + +   V  +  LP + +SP
Sbjct: 1190 DRIAIISHGKLKCCGSPLFLKGTYGDGYRLTLVKRPAEPGGPQEPGLASSPPGRAPLSSCSELQVSQFIRKHVASCLLVSDTSTELSYILPSEAAKKGAFERLFQHLERSLDALHLSSFGLMDTTLEEVFLKVSEEDQSLENSEADVKESRKD--VLPGAEGPASGEGHAGNLARCSELTQSQASLQSASSVGSARGDEGAGYTDVYGDY---RPLFDNPQDPDNVSLQEVEAEALSRVGQGSRKLDGGWLKVRQFHGLLVKRFHCARRNSKALFSQILLPAFFVCVAMTVALSVPEIGDLPPLVLSP 1492

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Match: abt-2 (ABC Transporter family [Source:UniProtKB/TrEMBL;Acc:Q1RS86])

HSP 1 Score: 143.28 bits (360), Expect = 1.912e-34
Identity = 154/556 (27.70%), Postives = 255/556 (45.86%), Query Frame = 2

Query: 1031 CDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDY-LLKNFQRLSRKI----FGGYQFLLPNDFAQSSKLIAQSPT-W-DGIRD-------------SVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFS---RIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLILLEVTLAIY----VILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIC-SKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLG----RGIMDLFFNYFYNSNSIVKHEY----------NALQWDIAGEKLFSLFSLSIGWWIVLI---IIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSS---DQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            C C   G+    +       N  R+ T+ D++ +LTG N++ + L+  F +L+        GG+     N  AQS   I  S   W + I+D              +  + P+ L+P        +  N   + ++     ++W N+K +   P  +NILSN LLR     + +  + GI   N+P+  + ++    N L   +  LA++    ++L LS I A F ++L+++RI  +   Q V G+    YWV+++L+D++ Y + II+I++I++ F    +        AF+LL   +G++ I + Y F    S  + +FV++   +  VG +  ++  +L+ L V    L   + +   VFL+ PQ+NLG    RG+M ++      SN + +             + L +D  G  +  LF   I   I LI   + E G V R     L ++ + R E    +D DV  ER+R+ +   D   +  L V NL K YN  L                     +AV  + F V  GECFGLLG+NGAGKTTTF
Sbjct: 1317 CGCEDFGWNCTLEDWKWNETNWLRLNTT-DRIFDLTGRNLTQFRLITRFAQLANTTAPFFLGGFSLGHVNQRAQSQADIDTSKRGWLETIKDIAQSMRIINLNTTGIEPATPKVLDPFAQNITLNQVVNDLLQNLDVRENVKVWFNNKIWPGFPIASNILSNALLRQE-DYAIDPEDLGILTMNHPMNKTISQTLDQNALKFTQA-LAVFRITILLLVLSMIPAGFTVYLVEDRICEALHLQLVGGLRKVTYWVTSYLYDMVVYTLVIIVIMLIYLCFRVSDFTADGATFFAFLLLFFVHGMSTILYAYVFQKAFSVAALSFVLIAIGSYFVGIVCALTVIMLESLMVQDPSLIPAHTVCSIVFLVLPQYNLGIAIFRGLM-IYQVRAIGSNFLQQMNRPDMINQLPLPSLLAFDQMGIHIMCLFIHVIIATICLIFSQMDEFGFV-RKRERNLTDAMMLR-EPSTCDDEDVVKERQRVDAIPMDSSDNHALIVRNLAKAYNPEL---------------------LAVKGISFAVEPGECFGLLGLNGAGKTTTF 1845

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Match: abt-2 (ABC Transporter family [Source:UniProtKB/TrEMBL;Acc:Q1RS86])

HSP 1 Score: 143.28 bits (360), Expect = 2.089e-34
Identity = 154/556 (27.70%), Postives = 255/556 (45.86%), Query Frame = 2

Query: 1031 CDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDY-LLKNFQRLSRKI----FGGYQFLLPNDFAQSSKLIAQSPT-W-DGIRD-------------SVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFS---RIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLILLEVTLAIY----VILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIC-SKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLG----RGIMDLFFNYFYNSNSIVKHEY----------NALQWDIAGEKLFSLFSLSIGWWIVLI---IIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSS---DQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            C C   G+    +       N  R+ T+ D++ +LTG N++ + L+  F +L+        GG+     N  AQS   I  S   W + I+D              +  + P+ L+P        +  N   + ++     ++W N+K +   P  +NILSN LLR     + +  + GI   N+P+  + ++    N L   +  LA++    ++L LS I A F ++L+++RI  +   Q V G+    YWV+++L+D++ Y + II+I++I++ F    +        AF+LL   +G++ I + Y F    S  + +FV++   +  VG +  ++  +L+ L V    L   + +   VFL+ PQ+NLG    RG+M ++      SN + +             + L +D  G  +  LF   I   I LI   + E G V R     L ++ + R E    +D DV  ER+R+ +   D   +  L V NL K YN  L                     +AV  + F V  GECFGLLG+NGAGKTTTF
Sbjct: 1280 CGCEDFGWNCTLEDWKWNETNWLRLNTT-DRIFDLTGRNLTQFRLITRFAQLANTTAPFFLGGFSLGHVNQRAQSQADIDTSKRGWLETIKDIAQSMRIINLNTTGIEPATPKVLDPFAQNITLNQVVNDLLQNLDVRENVKVWFNNKIWPGFPIASNILSNALLRQE-DYAIDPEDLGILTMNHPMNKTISQTLDQNALKFTQA-LAVFRITILLLVLSMIPAGFTVYLVEDRICEALHLQLVGGLRKVTYWVTSYLYDMVVYTLVIIVIMLIYLCFRVSDFTADGATFFAFLLLFFVHGMSTILYAYVFQKAFSVAALSFVLIAIGSYFVGIVCALTVIMLESLMVQDPSLIPAHTVCSIVFLVLPQYNLGIAIFRGLM-IYQVRAIGSNFLQQMNRPDMINQLPLPSLLAFDQMGIHIMCLFIHVIIATICLIFSQMDEFGFV-RKRERNLTDAMMLR-EPSTCDDEDVVKERQRVDAIPMDSSDNHALIVRNLAKAYNPEL---------------------LAVKGISFAVEPGECFGLLGLNGAGKTTTF 1808

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Match: ced-7 (ABC transporter ced-7 [Source:UniProtKB/Swiss-Prot;Acc:P34358])

HSP 1 Score: 118.627 bits (296), Expect = 8.405e-27
Identity = 90/340 (26.47%), Postives = 168/340 (49.41%), Query Frame = 2

Query: 1565 LLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIF-YGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFL-IFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDF--------DVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            L++V LA  +IL  + ++++FV+FLI+ER      QQF++GI+P  ++ ++ ++D + Y +  +I + +F+AF +       + LA ++L  F Y  + +P +Y  SF   +PS A V+L  + +++     ++ F++ ++    E+LK    IL  +F+ + P +  G  I+ +      N+  ++      + WD  G+  + + +  +  + + ++++   V R +    +   ++R    N +           V+ ERER+      +  L + +LTK +                       R  AVN LC  V + ECFGLLGVNGAGKTTTF
Sbjct: 1175 LIDVLLAPMLILIFAMVTSTFVMFLIEERTCQFAHQQFLTGISPITFYSASLIYDGILYSLICLIFLFMFLAFHWM-----YDHLAIVILFWFLYFFSSVPFIYAVSFLFQSPSKANVLLIIWQVVISGAALLAVFLIFMIFNIDEWLK---SILVNIFMFLLPSYAFGSAIITI------NTYGMILPSEELMNWDHCGKNAWLMGTFGVCSFALFVLLQFKFVRRFLS---QVWTVRRSSHNNVQPMMGDLPVCESVSEERERVHRVNSQNSALVIKDLTKTF----------------------GRFTAVNELCLAVDQKECFGLLGVNGAGKTTTF 1475

HSP 2 Score: 57.3806 bits (137), Expect = 5.334e-8
Identity = 59/233 (25.32%), Postives = 100/233 (42.92%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISN----------SGDKLLQFIKSHIPDA-KMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFL-----DLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAE 655
            D + I+S GKL   G++ +LK+KFG GY L +V + N  K      +++           G+   Q I+  +P+A K E   + Q    +   +  S  F  +   L  ++  L   S+GLS  +LE+VFI + D   K     +N ++  ++ N           EP L     D +   + A   + L+        K   G   +  Q I +  K+F Y++RN   +F +
Sbjct:  799 DWVFIMSHGKLVASGTNQYLKQKFGTGYLLTVVLDHNGDKRKMAVILTDVCTHYVKEAERGEMHGQQIEIILPEARKKEFVPLFQALEAIQDRNYRSNVFDNMPNTLKSQLATLEMRSFGLSLNTLEQVFITIGDKVDKAIASRQNSRISHNSRNA---------SEPSLKPAGYDTQSSTKSADSYQKLMDSQARGPEK--SGVAKMVAQFISIMRKKFLYSRRNWAQLFTQ 1020

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Match: ced-7 (ABC transporter ced-7 [Source:UniProtKB/Swiss-Prot;Acc:P34358])

HSP 1 Score: 118.242 bits (295), Expect = 1.088e-26
Identity = 90/340 (26.47%), Postives = 168/340 (49.41%), Query Frame = 2

Query: 1565 LLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIF-YGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFL-IFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDF--------DVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            L++V LA  +IL  + ++++FV+FLI+ER      QQF++GI+P  ++ ++ ++D + Y +  +I + +F+AF +       + LA ++L  F Y  + +P +Y  SF   +PS A V+L  + +++     ++ F++ ++    E+LK    IL  +F+ + P +  G  I+ +      N+  ++      + WD  G+  + + +  +  + + ++++   V R +    +   ++R    N +           V+ ERER+      +  L + +LTK +                       R  AVN LC  V + ECFGLLGVNGAGKTTTF
Sbjct: 1106 LIDVLLAPMLILIFAMVTSTFVMFLIEERTCQFAHQQFLTGISPITFYSASLIYDGILYSLICLIFLFMFLAFHWM-----YDHLAIVILFWFLYFFSSVPFIYAVSFLFQSPSKANVLLIIWQVVISGAALLAVFLIFMIFNIDEWLK---SILVNIFMFLLPSYAFGSAIITI------NTYGMILPSEELMNWDHCGKNAWLMGTFGVCSFALFVLLQFKFVRRFLS---QVWTVRRSSHNNVQPMMGDLPVCESVSEERERVHRVNSQNSALVIKDLTKTF----------------------GRFTAVNELCLAVDQKECFGLLGVNGAGKTTTF 1406

HSP 2 Score: 57.3806 bits (137), Expect = 5.485e-8
Identity = 59/233 (25.32%), Postives = 100/233 (42.92%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISN----------SGDKLLQFIKSHIPDA-KMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFL-----DLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAE 655
            D + I+S GKL   G++ +LK+KFG GY L +V + N  K      +++           G+   Q I+  +P+A K E   + Q    +   +  S  F  +   L  ++  L   S+GLS  +LE+VFI + D   K     +N ++  ++ N           EP L     D +   + A   + L+        K   G   +  Q I +  K+F Y++RN   +F +
Sbjct:  732 DWVFIMSHGKLVASGTNQYLKQKFGTGYLLTVVLDHNGDKRKMAVILTDVCTHYVKEAERGEMHGQQIEIILPEARKKEFVPLFQALEAIQDRNYRSNVFDNMPNTLKSQLATLEMRSFGLSLNTLEQVFITIGDKVDKAIASRQNSRISHNSRNA---------SEPSLKPAGYDTQSSTKSADSYQKLMDSQARGPEK--SGVAKMVAQFISIMRKKFLYSRRNWAQLFTQ 953

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Match: ced-7 (ABC transporter ced-7 [Source:UniProtKB/Swiss-Prot;Acc:P34358])

HSP 1 Score: 117.857 bits (294), Expect = 1.231e-26
Identity = 90/340 (26.47%), Postives = 168/340 (49.41%), Query Frame = 2

Query: 1565 LLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIF-YGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFL-IFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDF--------DVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            L++V LA  +IL  + ++++FV+FLI+ER      QQF++GI+P  ++ ++ ++D + Y +  +I + +F+AF +       + LA ++L  F Y  + +P +Y  SF   +PS A V+L  + +++     ++ F++ ++    E+LK    IL  +F+ + P +  G  I+ +      N+  ++      + WD  G+  + + +  +  + + ++++   V R +    +   ++R    N +           V+ ERER+      +  L + +LTK +                       R  AVN LC  V + ECFGLLGVNGAGKTTTF
Sbjct: 1121 LIDVLLAPMLILIFAMVTSTFVMFLIEERTCQFAHQQFLTGISPITFYSASLIYDGILYSLICLIFLFMFLAFHWM-----YDHLAIVILFWFLYFFSSVPFIYAVSFLFQSPSKANVLLIIWQVVISGAALLAVFLIFMIFNIDEWLK---SILVNIFMFLLPSYAFGSAIITI------NTYGMILPSEELMNWDHCGKNAWLMGTFGVCSFALFVLLQFKFVRRFLS---QVWTVRRSSHNNVQPMMGDLPVCESVSEERERVHRVNSQNSALVIKDLTKTF----------------------GRFTAVNELCLAVDQKECFGLLGVNGAGKTTTF 1421

HSP 2 Score: 57.3806 bits (137), Expect = 5.730e-8
Identity = 59/233 (25.32%), Postives = 100/233 (42.92%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISN----------SGDKLLQFIKSHIPDA-KMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFL-----DLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAE 655
            D + I+S GKL   G++ +LK+KFG GY L +V + N  K      +++           G+   Q I+  +P+A K E   + Q    +   +  S  F  +   L  ++  L   S+GLS  +LE+VFI + D   K     +N ++  ++ N           EP L     D +   + A   + L+        K   G   +  Q I +  K+F Y++RN   +F +
Sbjct:  745 DWVFIMSHGKLVASGTNQYLKQKFGTGYLLTVVLDHNGDKRKMAVILTDVCTHYVKEAERGEMHGQQIEIILPEARKKEFVPLFQALEAIQDRNYRSNVFDNMPNTLKSQLATLEMRSFGLSLNTLEQVFITIGDKVDKAIASRQNSRISHNSRNA---------SEPSLKPAGYDTQSSTKSADSYQKLMDSQARGPEK--SGVAKMVAQFISIMRKKFLYSRRNWAQLFTQ 966

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Match: CG34120 (gene:FBgn0083956 transcript:FBtr0110827)

HSP 1 Score: 122.865 bits (307), Expect = 4.769e-28
Identity = 105/402 (26.12%), Postives = 195/402 (48.51%), Query Frame = 2

Query: 1382 SRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLILLEV---TLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN------ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGE--KGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            + +W N+KGY SM A+ N L++ LLR+ +  S++S    I   N P      ++S   + IL +    ++   +++A   + AS  ++L++ER++G K QQ + G++   YW+   +WD +  ++ +I+ +++ + F    ++  +  +  I L + +  A +P ++      S  S A V +   NL+V  +T     IL ++     +  +    L + FLIFP   LG G ++L  NY     ++V   Y+       L  D+ G    +L  + +   I+ ++IE  ++ R+          +R+E       D    RE     Q     L+++N+  I+   +    + GE  + ++ ++  +    AV N+ F V+ GECFGLLG NGAGK+T F
Sbjct: 1324 ATVWYNNKGYHSMMAWLNDLNSELLRTTMNDSESS----ILTLNEPWKLGFAELS--TSSILRQAGDGSMVFILLIAFGLVVASGSVYLVNERVNGEKLQQRLCGVSAVTYWLVALVWDYLVMVLGLIVCLVVILMFGMPVFVDRQQLVGIIGLSLAFSFACVPSVHVAEKIFSDSSIAIVSIFCANLIVPLVTMGIILILGVVGDGPAW-DDWRHALNQAFLIFPIHALGDGFLELCKNYMV---ALVFRRYDIDSYKHPLASDLLGRHFTALLLVGVAALIINVLIEWHLLRRL---------WQRVE----RLLDCTYRRELDKLGQ-----LKLVNIQSIFKSCV----DTGEAVRAENLWLAYRRGHYAVRNVNFSVQRGECFGLLGKNGAGKSTIF 1693

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Match: CG34120 (gene:FBgn0083956 transcript:FBtr0343018)

HSP 1 Score: 122.865 bits (307), Expect = 5.065e-28
Identity = 105/402 (26.12%), Postives = 195/402 (48.51%), Query Frame = 2

Query: 1382 SRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLILLEV---TLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN------ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGE--KGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            + +W N+KGY SM A+ N L++ LLR+ +  S++S    I   N P      ++S   + IL +    ++   +++A   + AS  ++L++ER++G K QQ + G++   YW+   +WD +  ++ +I+ +++ + F    ++  +  +  I L + +  A +P ++      S  S A V +   NL+V  +T     IL ++     +  +    L + FLIFP   LG G ++L  NY     ++V   Y+       L  D+ G    +L  + +   I+ ++IE  ++ R+          +R+E       D    RE     Q     L+++N+  I+   +    + GE  + ++ ++  +    AV N+ F V+ GECFGLLG NGAGK+T F
Sbjct: 1325 ATVWYNNKGYHSMMAWLNDLNSELLRTTMNDSESS----ILTLNEPWKLGFAELS--TSSILRQAGDGSMVFILLIAFGLVVASGSVYLVNERVNGEKLQQRLCGVSAVTYWLVALVWDYLVMVLGLIVCLVVILMFGMPVFVDRQQLVGIIGLSLAFSFACVPSVHVAEKIFSDSSIAIVSIFCANLIVPLVTMGIILILGVVGDGPAW-DDWRHALNQAFLIFPIHALGDGFLELCKNYMV---ALVFRRYDIDSYKHPLASDLLGRHFTALLLVGVAALIINVLIEWHLLRRL---------WQRVE----RLLDCTYRRELDKLGQ-----LKLVNIQSIFKSCV----DTGEAVRAENLWLAYRRGHYAVRNVNFSVQRGECFGLLGKNGAGKSTIF 1694

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Match: CG34120 (gene:FBgn0083956 transcript:FBtr0299591)

HSP 1 Score: 122.479 bits (306), Expect = 6.588e-28
Identity = 105/402 (26.12%), Postives = 195/402 (48.51%), Query Frame = 2

Query: 1382 SRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLILLEV---TLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN------ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGE--KGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            + +W N+KGY SM A+ N L++ LLR+ +  S++S    I   N P      ++S   + IL +    ++   +++A   + AS  ++L++ER++G K QQ + G++   YW+   +WD +  ++ +I+ +++ + F    ++  +  +  I L + +  A +P ++      S  S A V +   NL+V  +T     IL ++     +  +    L + FLIFP   LG G ++L  NY     ++V   Y+       L  D+ G    +L  + +   I+ ++IE  ++ R+          +R+E       D    RE     Q     L+++N+  I+   +    + GE  + ++ ++  +    AV N+ F V+ GECFGLLG NGAGK+T F
Sbjct: 1308 ATVWYNNKGYHSMMAWLNDLNSELLRTTMNDSESS----ILTLNEPWKLGFAELS--TSSILRQAGDGSMVFILLIAFGLVVASGSVYLVNERVNGEKLQQRLCGVSAVTYWLVALVWDYLVMVLGLIVCLVVILMFGMPVFVDRQQLVGIIGLSLAFSFACVPSVHVAEKIFSDSSIAIVSIFCANLIVPLVTMGIILILGVVGDGPAW-DDWRHALNQAFLIFPIHALGDGFLELCKNYMV---ALVFRRYDIDSYKHPLASDLLGRHFTALLLVGVAALIINVLIEWHLLRRL---------WQRVE----RLLDCTYRRELDKLGQ-----LKLVNIQSIFKSCV----DTGEAVRAENLWLAYRRGHYAVRNVNFSVQRGECFGLLGKNGAGKSTIF 1677

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Match: ABCA (gene:FBgn0031170 transcript:FBtr0306679)

HSP 1 Score: 113.235 bits (282), Expect = 4.090e-25
Identity = 120/432 (27.78%), Postives = 204/432 (47.22%), Query Frame = 2

Query: 1364 SKTMNFSRI--WINSKGYASMPAYANILSNL----LLRSRIKLSQNSWNYGISVTNYPIA-DSETKISQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEY-LKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNAL-------------------QWDIAGEKLFSLFSLSIG--WWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTE---DFDVNLERER---MSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            + T+  S+I  W+N++   + P   N++ N     L  S +K         I VTN P+   + T +SQ +    L   LA  +   + F+S+ +++FLI ER S +K  QFV G+  + +W+S F+ D   YI+  +I++I  + F             + LLL+ +G A++P +Y  S F   P+T F  ++  N+  G    ++ FI+ ++  +  +  K+  DIL  +F IFP F+L   +  ++ N     N+  K    AL                    W+  G    +++    G  +++++I++E  ++N ++  K++   + +     TE   D DV  ERER   MSS++ +   L +  +TK Y  ++                      AVN +   V+E ECFGLLGVNGAGKTTTF
Sbjct: 1020 AATITESKITAWLNNQALHTAPLTVNMVHNAIADKLFGSSVK---------IQVTNAPLPYTTSTLLSQLSTGNNLGTQLASNLCFCMCFVSSIYILFLIKERESRAKLLQFVGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETGLSTFGELGRYYLLLLLFGFAVLPFIYIMSLFFREPATGFARVSIVNIFCG----MALFIVVVVMSSELFDTKDTADILGWIFRIFPHFSLAMSLNKVYTNT-ATRNACAKA--GALPPILLCELVPQCCNLKPYFAWEEPGVLPETVYMAVTGVVFFLIIIVLEFRLINELMF-KIRQ-LISKPPPPPTEGQLDDDVANERERILQMSSNELATKNLVLDRVTKYYGQFM----------------------AVNQVSLCVQEVECFGLLGVNGAGKTTTF 1411

HSP 2 Score: 87.8113 bits (216), Expect = 3.250e-17
Identity = 70/212 (33.02%), Postives = 104/212 (49.06%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNK 637
             DRIAI+  G+L+C G+S FLK+++G GYRLI VK  + +            +++   +  +IP  K E +   + S+ LP  DS S KF  +F  L+E+ D L+   YG+  TS+EEVF++V  +               DN   I    +I N       ED N+    D       F+ N +LL+G  LL  Q   + +K+F Y  RNK
Sbjct:  734 GDRIAIMCDGELKCQGTSFFLKKQYGSGYRLICVKRDDCET-----------NEVTALLNKYIPGLKPECDIGAELSYQLP--DSASAKFEEMFGQLEEQSDELHLNGYGVGITSMEEVFMKVGAE--------------KDNTGNIKDQHEIMNGGSGFRGEDDNESVQSDGI-----FSENRRLLQGLQLLSNQWKAMLLKKFLYTWRNK 913

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Match: ABCA (gene:FBgn0031170 transcript:FBtr0332489)

HSP 1 Score: 113.235 bits (282), Expect = 4.707e-25
Identity = 120/432 (27.78%), Postives = 204/432 (47.22%), Query Frame = 2

Query: 1364 SKTMNFSRI--WINSKGYASMPAYANILSNL----LLRSRIKLSQNSWNYGISVTNYPIA-DSETKISQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEY-LKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNAL-------------------QWDIAGEKLFSLFSLSIG--WWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTE---DFDVNLERER---MSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            + T+  S+I  W+N++   + P   N++ N     L  S +K         I VTN P+   + T +SQ +    L   LA  +   + F+S+ +++FLI ER S +K  QFV G+  + +W+S F+ D   YI+  +I++I  + F             + LLL+ +G A++P +Y  S F   P+T F  ++  N+  G    ++ FI+ ++  +  +  K+  DIL  +F IFP F+L   +  ++ N     N+  K    AL                    W+  G    +++    G  +++++I++E  ++N ++  K++   + +     TE   D DV  ERER   MSS++ +   L +  +TK Y  ++                      AVN +   V+E ECFGLLGVNGAGKTTTF
Sbjct:  998 AATITESKITAWLNNQALHTAPLTVNMVHNAIADKLFGSSVK---------IQVTNAPLPYTTSTLLSQLSTGNNLGTQLASNLCFCMCFVSSIYILFLIKERESRAKLLQFVGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETGLSTFGELGRYYLLLLLFGFAVLPFIYIMSLFFREPATGFARVSIVNIFCG----MALFIVVVVMSSELFDTKDTADILGWIFRIFPHFSLAMSLNKVYTNT-ATRNACAKA--GALPPILLCELVPQCCNLKPYFAWEEPGVLPETVYMAVTGVVFFLIIIVLEFRLINELMF-KIRQ-LISKPPPPPTEGQLDDDVANERERILQMSSNELATKNLVLDRVTKYYGQFM----------------------AVNQVSLCVQEVECFGLLGVNGAGKTTTF 1389

HSP 2 Score: 87.8113 bits (216), Expect = 3.294e-17
Identity = 70/212 (33.02%), Postives = 104/212 (49.06%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNK 637
             DRIAI+  G+L+C G+S FLK+++G GYRLI VK  + +            +++   +  +IP  K E +   + S+ LP  DS S KF  +F  L+E+ D L+   YG+  TS+EEVF++V  +               DN   I    +I N       ED N+    D       F+ N +LL+G  LL  Q   + +K+F Y  RNK
Sbjct:  712 GDRIAIMCDGELKCQGTSFFLKKQYGSGYRLICVKRDDCET-----------NEVTALLNKYIPGLKPECDIGAELSYQLP--DSASAKFEEMFGQLEEQSDELHLNGYGVGITSMEEVFMKVGAE--------------KDNTGNIKDQHEIMNGGSGFRGEDDNESVQSDGI-----FSENRRLLQGLQLLSNQWKAMLLKKFLYTWRNK 891

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
Match: abca1b (ATP-binding cassette, sub-family A (ABC1), member 1B [Source:ZFIN;Acc:ZDB-GENE-030131-9826])

HSP 1 Score: 387.111 bits (993), Expect = 7.871e-115
Identity = 293/931 (31.47%), Postives = 479/931 (51.45%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG---DK-------------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQ--EPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCM-NPSIYRSTHYRCFPEYKNNKWSP--IPNGNIPLI----------SPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQR-----LSRKI------FGGYQFLLPNDFAQSSKLIAQSPTWDG----IRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN----ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIV--NRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 +F  + +N  +  S++G   D+             + + I  H+P A+M  +   + ++VLP   + +  F  LF +LD+ + +L   SYG+SDT+LEE+F++VA+D + ++ E  ++  +P    R   +G       +P    D  D N+     +S     +S +  +    ++G+ L +QQ + L  KR  YA+R++KG FA+++LP + + + +    +V P    P++ ++PW+                E Q  F            +  T +L      D G  G RCM   SI  +    C     + +WS   +P   I ++          SP C+C+  G +     C     G PP   +I + ++ L NLTG NISDYL+K + +     L  KI      +GG+        A+S++++  +   D     +R+     +       RFLK    F N    T N  +IW N+KG+ S+ A+ N+++N +LR+ +   ++   +GI+  N+P+  ++ ++SQ   +   ++V ++I VI A+SF+ ASFV+FLI ER++ +K  QF+SG+ PY+YW++NFLWD+  Y++P  ++I+IF+ F  ++Y+ + N     LLL+ YG +I P MYP SF    PSTA+VVL + N+L+G   +ISTF++++   N+E +  INDILK V LIFP F LGRG++D+  N    ++++ +   N     L+WD+ G+ LF++    + ++I+ ++I+       + +C KL             ED DV  ER+R+ S     D+L +  LTK+Y                     + ++ AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1100 GDRIAIISHGKLCCVGSSLFLKTQLGTGYYLTLVKKNTEPSLSSCRNSSSTVSFVKKDDNASESSSDAGLGSDQESEAATAIVDVTIISRLILKHVPAARMVEDQGHEITYVLPYESAKNGAFVELFHDLDDRLADLGISSYGVSDTTLEEIFLKVAED-SGVDTEMLSDGTLPVRRQRRHAFGADHQSCLKPLTEDDSFDCNESEGDPESKETDYLSGSDGKGSYQVKGWSLKRQQFVALLWKRLLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLALNPWMY---------------EEQFMF-----FSEDAPYDVSTHKLLRALFDDPG-FGTRCMKGESIPDAP---C--TMGDEEWSTPEVPESIIEILTTRNWTMNDPSPACECSCNGKKKMLPECPAGAGGLPPPQIKI-SETETLQNLTGRNISDYLVKTYAQIIGKSLKNKIWVNEFRYGGFSL-----GARSTQVLPPAEEIDDAISRVREIFQLGKDSGSAADRFLKSLSAFIN-GLDTKNNVKIWFNNKGWHSIGAFLNVMNNGILRANLPPGKDPSEFGITAYNHPLNLTKEQLSQVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPYLYWLANFLWDMCNYVVPATLVILIFVCFQQKAYVSATNLPVLALLLLLYGWSITPLMYPASFLFKIPSTAYVVLTSVNILIGINGSISTFVMELFG-NHE-IGGINDILKNVLLIFPHFCLGRGLIDMVKNQAM-ADALERFGENRFRSPLEWDMVGKNLFAMAVEGVVFFIITVLIQYRFFFEPKSLCPKLSPI--------GEEDEDVARERQRIMSGAGQGDILELRQLTKVY--------------------KRKQKPAVDRLCVGIPPGECFGLLGVNGAGKTSTF 1965

HSP 2 Score: 51.9878 bits (123), Expect = 4.298e-6
Identity = 34/122 (27.87%), Postives = 60/122 (49.18%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVA 373
            R+AI+  G+ +C GS   LK +FGDGY +IL             G       +++FI+S +P + ++ +      + LP   S+    + +F  L +  + L    Y +S T+L++VF+  A
Sbjct: 2122 RMAIMVNGRFRCLGSVQHLKNRFGDGYTIILRV----------AGPDPDLQPVMKFIESELPGSTLKEKHRNMLQYQLP---SSLTSLAHIFSILAKNKEFLRIEDYSVSQTTLDQVFVNFA 2230

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
Match: abca1b (ATP-binding cassette, sub-family A (ABC1), member 1B [Source:ZFIN;Acc:ZDB-GENE-030131-9826])

HSP 1 Score: 382.874 bits (982), Expect = 2.190e-113
Identity = 293/942 (31.10%), Postives = 479/942 (50.85%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG---DK------------------------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQ--EPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCM-NPSIYRSTHYRCFPEYKNNKWSP--IPNGNIPLI----------SPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQR-----LSRKI------FGGYQFLLPNDFAQSSKLIAQSPTWDG----IRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN----ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIV--NRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 +F  + +N  +  S++G   D+                        + + I  H+P A+M  +   + ++VLP   + +  F  LF +LD+ + +L   SYG+SDT+LEE+F++VA+D + ++ E  ++  +P    R   +G       +P    D  D N+     +S     +S +  +    ++G+ L +QQ + L  KR  YA+R++KG FA+++LP + + + +    +V P    P++ ++PW+                E Q  F            +  T +L      D G  G RCM   SI  +    C     + +WS   +P   I ++          SP C+C+  G +     C     G PP   +I + ++ L NLTG NISDYL+K + +     L  KI      +GG+        A+S++++  +   D     +R+     +       RFLK    F N    T N  +IW N+KG+ S+ A+ N+++N +LR+ +   ++   +GI+  N+P+  ++ ++SQ   +   ++V ++I VI A+SF+ ASFV+FLI ER++ +K  QF+SG+ PY+YW++NFLWD+  Y++P  ++I+IF+ F  ++Y+ + N     LLL+ YG +I P MYP SF    PSTA+VVL + N+L+G   +ISTF++++   N+E +  INDILK V LIFP F LGRG++D+  N    ++++ +   N     L+WD+ G+ LF++    + ++I+ ++I+       + +C KL             ED DV  ER+R+ S     D+L +  LTK+Y                     + ++ AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1100 GDRIAIISHGKLCCVGSSLFLKTQLGTGYYLTLVKKNTEPSLSSCRNSSSTVSFVKKDDNASESSSDAGLGSDQESEAATAIGTSWPESPVVPVDVTIISRLILKHVPAARMVEDQGHEITYVLPYESAKNGAFVELFHDLDDRLADLGISSYGVSDTTLEEIFLKVAED-SGVDTEMLSDGTLPVRRQRRHAFGADHQSCLKPLTEDDSFDCNESEGDPESKETDYLSGSDGKGSYQVKGWSLKRQQFVALLWKRLLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLALNPWMY---------------EEQFMF-----FSEDAPYDVSTHKLLRALFDDPG-FGTRCMKGESIPDAP---C--TMGDEEWSTPEVPESIIEILTTRNWTMNDPSPACECSCNGKKKMLPECPAGAGGLPPPQIKI-SETETLQNLTGRNISDYLVKTYAQIIGKSLKNKIWVNEFRYGGFSL-----GARSTQVLPPAEEIDDAISRVREIFQLGKDSGSAADRFLKSLSAFIN-GLDTKNNVKIWFNNKGWHSIGAFLNVMNNGILRANLPPGKDPSEFGITAYNHPLNLTKEQLSQVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPYLYWLANFLWDMCNYVVPATLVILIFVCFQQKAYVSATNLPVLALLLLLYGWSITPLMYPASFLFKIPSTAYVVLTSVNILIGINGSISTFVMELFG-NHE-IGGINDILKNVLLIFPHFCLGRGLIDMVKNQAM-ADALERFGENRFRSPLEWDMVGKNLFAMAVEGVVFFIITVLIQYRFFFEPKSLCPKLSPI--------GEEDEDVARERQRIMSGAGQGDILELRQLTKVY--------------------KRKQKPAVDRLCVGIPPGECFGLLGVNGAGKTSTF 1976

HSP 2 Score: 51.6026 bits (122), Expect = 4.562e-6
Identity = 34/122 (27.87%), Postives = 60/122 (49.18%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVA 373
            R+AI+  G+ +C GS   LK +FGDGY +IL             G       +++FI+S +P + ++ +      + LP   S+    + +F  L +  + L    Y +S T+L++VF+  A
Sbjct: 2133 RMAIMVNGRFRCLGSVQHLKNRFGDGYTIILRV----------AGPDPDLQPVMKFIESELPGSTLKEKHRNMLQYQLP---SSLTSLAHIFSILAKNKEFLRIEDYSVSQTTLDQVFVNFA 2241

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
Match: abca1a (ATP-binding cassette, sub-family A (ABC1), member 1A [Source:ZFIN;Acc:ZDB-GENE-031006-12])

HSP 1 Score: 362.073 bits (928), Expect = 2.318e-106
Identity = 284/912 (31.14%), Postives = 466/912 (51.10%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-NFNA--------------QKENFRK-----------GISNSGDK---------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-DLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRL-ESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPL--ISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLP---NDFAQSSKLIAQSPTWDGIRDSVNQ-----SQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN----ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK +F+                K + +K           G+ +  +          +   I  H+P A++  +   + ++VLP   +    F  LF  +D+ + +L+  SYG+SDT+LEE+F++VA+D   ++ ET +  L P   NR   +GD ++  +PF + + D N      +S     +     +    ++G+ L +QQ + L  KR  YA+R++KG FA+++LP + + + +    +V P    P++ + P +                E Q  F I+N        N L D L +S   +D    G    + S          PE   +  +   NGN  +   SP C+C+  G +     C     G PP   ++ T  + L NL+G NISDYL+K + ++  K      ++       F+  ++     P  D + D+++      S        RFL     F  +   T N  +IW N+KG+ S+ ++ N+++N +LR+ +    +   +GI+  N+P+  ++ ++S    +   ++V ++I VI A+SF+ ASFV+FLI ER++ +K  QF+SG+ P++YW++NF+WD+  YI+P  ++IIIF+ F  ++Y+ S N     LLL+ YG +I P MYP SFF   PSTA+VVL + N+L+G   ++STF+L++   N   +  INDILK VFLIFP F LGRG++D+  N    ++++ +   N     L WD+ G+ LF++    + ++ + ++I+        C K + S   +++    ED DV  ER+R+       D+L +  LTK+Y                     + ++ AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1101 GDRIAIISHGKLCCVGSSLFLKTQLGTGYYLTLVKKDFDLSASSCRTSSSTVSYSKGSLKKDDSVSESSSDAGLGSDHESETTTIDISLISNVIFKHVPTARLVEDLGHEITYVLPYESAKDGAFVELFHEIDDRLTDLSISSYGISDTTLEEIFLKVAED-CGVDAETSDGTL-PARRNRRHAFGDHQSCLKPFTEDDFDFNDSEGDPESRETDWLDGADGKGSYQVKGWSLKRQQFVALLWKRLLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLALEPSMY---------------EEQFTF-ISNDAPEDRHTNRLLDALKDSPAYTDQCTDGKNTASRSCPIKDGEWLVPEVTESIEAIFLNGNWSMENPSPLCECSCEGRKKMLPECPPGAGGLPPPQIKV-THDETLQNLSGRNISDYLVKTYAQIIGKSLKNKLWVNEFRYGGFSLGARNTQALPPGDELTDAISHIRSRFSLESGTAADRFLGSLSTFI-RGLDTNNNVKIWFNNKGWHSIGSFLNVMNNAVLRANLPPGLDRSKFGINAFNHPLNLTKEQLSHVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPFLYWLANFVWDMCNYIVPATLVIIIFVCFQQEAYVSSTNLPVLALLLLLYGWSITPLMYPASFFFKIPSTAYVVLTSVNILIGINGSVSTFVLELFGSN--EIGGINDILKNVFLIFPHFCLGRGLIDMVKNQAM-ADALERFGENRFRSPLAWDMVGKNLFAMAIEGVIFFSITVLIQYR-----FCIKAR-SLSTKLKPIGEEDEDVARERQRILGGGGQTDILELRQLTKVY--------------------KRKQKPAVDRLCVGIPPGECFGLLGVNGAGKTSTF 1963

HSP 2 Score: 52.7582 bits (125), Expect = 2.500e-6
Identity = 34/124 (27.42%), Postives = 61/124 (49.19%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G+ +C GS   LK KFGDGY +IL             G     + +++FI+  +P + ++ +      +   Q  S+    + +F  L +  + L+   Y +S T+L++VF+  A D
Sbjct: 2120 RMAIMVNGRFRCLGSVQHLKNKFGDGYTIILRV----------AGADPRLEPVMEFIERELPGSTLKEKHRNMLQY---QLSSSLTSLARIFNILSKNKEQLHIEDYSVSQTTLDQVFVNFAKD 2230

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Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-NFNA--------------QKENFRK-----------GISNSGDK---------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-DLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRL-ESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPL--ISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLP---NDFAQSSKLIAQSPTWDGIRDSVNQ-----SQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN----ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK +F+                K + +K           G+ +  +          +   I  H+P A++  +   + ++VLP   +    F  LF  +D+ + +L+  SYG+SDT+LEE+F++VA+D   ++ ET +  L P   NR   +GD ++  +PF + + D N      +S     +     +    ++G+ L +QQ + L  KR  YA+R++KG FA+++LP + + + +    +V P    P++ + P +                E Q  F I+N        N L D L +S   +D    G    + S          PE   +  +   NGN  +   SP C+C+  G +     C     G PP   ++ T  + L NL+G NISDYL+K + ++  K      ++       F+  ++     P  D + D+++      S        RFL     F  +   T N  +IW N+KG+ S+ ++ N+++N +LR+ +    +   +GI+  N+P+  ++ ++S    +   ++V ++I VI A+SF+ ASFV+FLI ER++ +K  QF+SG+ P++YW++NF+WD+  YI+P  ++IIIF+ F  ++Y+ S N     LLL+ YG +I P MYP SFF   PSTA+VVL + N+L+G   ++STF+L++   N   +  INDILK VFLIFP F LGRG++D+  N    ++++ +   N     L WD+ G+ LF++    + ++ + ++I+        C K + S   +++    ED DV  ER+R+       D+L +  LTK+Y                     + ++ AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1101 GDRIAIISHGKLCCVGSSLFLKTQLGTGYYLTLVKKDFDLSASSCRTSSSTVSYSKGSLKKDDSVSESSSDAGLGSDHESETTTIDISLISNVIFKHVPTARLVEDLGHEITYVLPYESAKDGAFVELFHEIDDRLTDLSISSYGISDTTLEEIFLKVAED-CGVDAETSDGTL-PARRNRRHAFGDHQSCLKPFTEDDFDFNDSEGDPESRETDWLDGADGKGSYQVKGWSLKRQQFVALLWKRLLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLALEPSMY---------------EEQFTF-ISNDAPEDRHTNRLLDALKDSPAYTDQCTDGKNTASRSCPIKDGEWLVPEVTESIEAIFLNGNWSMENPSPLCECSCEGRKKMLPECPPGAGGLPPPQIKV-THDETLQNLSGRNISDYLVKTYAQIIGKSLKNKLWVNEFRYGGFSLGARNTQALPPGDELTDAISHIRSRFSLESGTAADRFLGSLSTFI-RGLDTNNNVKIWFNNKGWHSIGSFLNVMNNAVLRANLPPGLDRSKFGINAFNHPLNLTKEQLSHVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPFLYWLANFVWDMCNYIVPATLVIIIFVCFQQEAYVSSTNLPVLALLLLLYGWSITPLMYPASFFFKIPSTAYVVLTSVNILIGINGSVSTFVLELFGSN--EIGGINDILKNVFLIFPHFCLGRGLIDMVKNQAM-ADALERFGENRFRSPLAWDMVGKNLFAMAIEGVIFFSITVLIQYR-----FCIKAR-SLSTKLKPIGEEDEDVARERQRILGGGGQTDILELRQLTKVY--------------------KRKQKPAVDRLCVGIPPGECFGLLGVNGAGKTSTF 1963

HSP 2 Score: 52.7582 bits (125), Expect = 2.500e-6
Identity = 34/124 (27.42%), Postives = 61/124 (49.19%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G+ +C GS   LK KFGDGY +IL             G     + +++FI+  +P + ++ +      +   Q  S+    + +F  L +  + L+   Y +S T+L++VF+  A D
Sbjct: 2120 RMAIMVNGRFRCLGSVQHLKNKFGDGYTIILRV----------AGADPRLEPVMEFIERELPGSTLKEKHRNMLQY---QLSSSLTSLARIFNILSKNKEQLHIEDYSVSQTTLDQVFVNFAKD 2230

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
Match: abca4b (ATP-binding cassette, sub-family A (ABC1), member 4b [Source:ZFIN;Acc:ZDB-GENE-050517-4])

HSP 1 Score: 362.073 bits (928), Expect = 2.864e-106
Identity = 275/918 (29.96%), Postives = 438/918 (47.71%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQ--KENF--------------------------RKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQA-FVDKSLIS-LNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCF------------PEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIF----------------GGYQFLLPNDFAQSSKLIAQSPTWDGIRDS-VNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFN-YFYNSNSIVKHEY--NALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            SDR+AIIS+GKL C GS +FLK  FG G+ L LV+    Q  KEN                            + +  + + +   I  H+P+AK+      + +++LP        ++ LF  L+E + ++   S+G+SDTSLEE+F++V  D      E  N  + P+      +    +N   F+    L + A  V  SL S  +  R  + ++GF L+ +Q   L +KRFH+A R+ K   A+++LP   + + +    +V P    P + ++PW+  P               Q  F     + N+   +P           D G  G RCM      +  + C             PE  N   SP  +   P  SP C+C+T    T   +C     G PP   R   + D L ++T  NISDYL+K + +L +                   GG   +L  D  +   + +Q      IR    ++S    LE   FL Y +  +N         ++W N+KG+ +M ++ N+ +N +LR+ +    N  +YGI+  N+P+  ++ ++S+   L   ++  +AI VI A+SFI ASFV++LI ER++ +K  QFVSG++P VYW +NF WD++ Y +   +++ IF+ FD + Y    N  A I LL  YG ++ P MYP S+  + PSTA+V L+  NL +G  ++  TFIL++ E N   L   N++LKKV L+FP F LGRG++D+  N    +  +    E+  +  +W+  G+ LF +      ++I  ++I+     +       + Y   + +   ED DV  ERER+      +D+L + +L+K Y                     + +  AV+ +C GV  GECFGLLGVNGAGKTTTF
Sbjct: 1178 SDRVAIISKGKLHCSGSPLFLKNCFGVGFYLTLVRRMKDQRKKENECDCASECSCTCSTCTRYKEESQALQPERVLDGNVESITTLIHHHVPEAKLIEMIGQEMTYLLPNKGFKYRAYASLFRELEETLGDMGLSSFGISDTSLEEIFLKVTAD-----GEAANSSVTPEQW----MLQQRKNGNGFMKDTGLAEDANGVGASLESDSSEGRASRQVKGFSLVLKQFHALLVKRFHHATRSHKDFLAQIVLPASFVLIALVFTMIVPPFGEYPCLTLTPWMYGP---------------QFTF-----ISNEQPSHPKMKHFIQTLLKDPG-MGTRCMANQPLENI-FTCLNSSSDWEVPPVSPEVSNILSSPEWDSRNP--SPSCECSTDLKLTMLPMCPAGAGGLPPRQ-RKEPTGDILLDMTNRNISDYLVKTYTKLIKTSLKSKYWVNEQRYGGISVGGRLPILDVDPEEIQNIFSQLGRMMNIRGGRYSKSAMDELE--TFLHYMESEYN--------VKVWYNNKGWHAMASFLNVANNAILRAYLPPHANPSDYGITAINHPLNLTKEQLSEVTVLTTSVDAVVAICVIFAMSFIPASFVLYLIQERVTKAKHLQFVSGVSPLVYWFANFFWDMLNYSVSTAMVVAIFVGFDKKCYTSPTNLPALIALLCLYGWSVTPMMYPLSYMFNVPSTAYVSLSCINLFIGINSSAITFILELFENNRSLLM-FNEVLKKVLLVFPHFCLGRGLIDMAMNQAVTDVYARFGEEFSMDPFRWNFVGKNLFCMAVEGFVYFIFNLLIQY----KFFLHHWISDY--GMSLGTDEDDDVAQERERIYKGGNKNDILLIRDLSKTY--------------------RRRKRPAVDKICVGVPAGECFGLLGVNGAGKTTTF 2024

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 394.815 bits (1013), Expect = 2.672e-117
Identity = 292/914 (31.95%), Postives = 473/914 (51.75%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFN-----------------AQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-------DLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--CMNPSIYRSTHY---RCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQ-----PQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYF-------YNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESG--IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK  N                  ++++  +  S++G                +   I  H+P+A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG++DT+LEE+F++VADD   ++ ET +  L P    R A +GD ++   PF + +       D++ ++     L  ++   +++L + + L++QQ   L  KR  YAKR++KG FA+++LP + + + +    +V P    P++E+ PW+   +       TF+  +        +  G +  +  L D+         G S ++  C       ST +        + N  W+      +   SP C+C++   +    IC  P +GG P   R   +SD L NLTG NISDYL+K + ++  K +GG+     N  A         P  + +  S+N  +     PQN    RFL  F  F  K   T +  ++W N+KG+ ++ A+ N+++N +LRS+++  ++  +YGI+  N+P+  ++ ++S+   +   ++V ++I VI A+SF+ ASFV+FLI ER+S +K  Q +SG+ P +YW++NF+WD+  Y++P  ++IIIFI F   SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   N   L  IN+ILK V LIFP F LGRG++D+  N         +  N  V    + + WD+ G  LF++    + ++ + ++I+    I  R +  KL             ED DV  ER+R++   + +D+L +  LTKIY +                     R+ AV+ LC G+  GECFGLLGVNGAGKTTTF
Sbjct: 1097 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKRDNDSSLSSCRNSSSTMSYLKKEDSVSQSSSDAGLGSDHESDTMTIDVSAISNLINKHVPEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGIADTTLEEIFLKVADDTG-VDAETSDGTL-PARRKRYA-FGDHQSCLRPFTEDDAFDTNDSDMDPESRETDYLSGIDGKGSYQL-KSWNLMRQQFTALLWKRLLYAKRSRKGFFAQIVLPAVFVLIALVFSLIVPPFGKYPSLELEPWMYDEQY------TFFSND------APDDQGTQALLKALIDKPGFGTACMEGHSVMKVSCSGEEEEWSTQFVSQSVMDLFLNGNWT------MENPSPSCECSSDKRKKMLPIC-PPGAGGLPPFQRRQNTSDILQNLTGRNISDYLVKTYSQIIEKRYGGFSLGASNSPAL--------PPNEEVVASINHIKKRLELPQNGAANRFLDSFGAFM-KGLDTKDNVKVWFNNKGWHAVGAFLNVMNNAILRSKLREGEDPASYGITAFNHPLNLTKEQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHMQCISGVKPVIYWLANFVWDMCNYVVPATLVIIIFICFQQDSYVSSSNLPVLALLLLLYGWSITPLMYPASFIFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTNN--KLSNINEILKSVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFV----SPMSWDLVGRNLFAMAVEGVVFFAITLMIQYRFFIKPRPVNAKLPPVV--------DEDEDVARERQRINEGGR-NDILELKGLTKIYRM--------------------KRKPAVDRLCVGIPPGECFGLLGVNGAGKTTTF 1943

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 385.571 bits (989), Expect = 3.387e-114
Identity = 292/928 (31.47%), Postives = 473/928 (50.97%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFN-----------------AQKENFRKGISNSG-----------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-------DLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--CMNPSIYRSTHY---RCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKI-----------FGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQ-----PQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYF-------YNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESG--IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK  N                  ++++  +  S++G                   +   I  H+P+A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG++DT+LEE+F++VADD   ++ ET +  L P    R A +GD ++   PF + +       D++ ++     L  ++   +++L + + L++QQ   L  KR  YAKR++KG FA+++LP + + + +    +V P    P++E+ PW+   +       TF+  +        +  G +  +  L D+         G S ++  C       ST +        + N  W+      +   SP C+C++   +    IC  P +GG P   R   +SD L NLTG NISDYL+K + ++  K            +GG+     N  A         P  + +  S+N  +     PQN    RFL  F  F  K   T +  ++W N+KG+ ++ A+ N+++N +LRS+++  ++  +YGI+  N+P+  ++ ++S+   +   ++V ++I VI A+SF+ ASFV+FLI ER+S +K  Q +SG+ P +YW++NF+WD+  Y++P  ++IIIFI F   SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   N   L  IN+ILK V LIFP F LGRG++D+  N         +  N  V    + + WD+ G  LF++    + ++ + ++I+    I  R +  KL             ED DV  ER+R++   + +D+L +  LTKIY +                     R+ AV+ LC G+  GECFGLLGVNGAGKTTTF
Sbjct: 1101 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKRDNDSSLSSCRNSSSTMSYLKKEDSVSQSSSDAGLGSDHESDTMTIGLTDVSAISNLINKHVPEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGIADTTLEEIFLKVADDTG-VDAETSDGTL-PARRKRYA-FGDHQSCLRPFTEDDAFDTNDSDMDPESRETDYLSGIDGKGSYQL-KSWNLMRQQFTALLWKRLLYAKRSRKGFFAQIVLPAVFVLIALVFSLIVPPFGKYPSLELEPWMYDEQY------TFFSND------APDDQGTQALLKALIDKPGFGTACMEGHSVMKVSCSGEEEEWSTQFVSQSVMDLFLNGNWT------MENPSPSCECSSDKRKKMLPIC-PPGAGGLPPFQRRQNTSDILQNLTGRNISDYLVKTYSQIIEKSLKNKIWVNEFRYGGFSLGASNSPAL--------PPNEEVVASINHIKKRLELPQNGAANRFLDSFGAFM-KGLDTKDNVKVWFNNKGWHAVGAFLNVMNNAILRSKLREGEDPASYGITAFNHPLNLTKEQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHMQCISGVKPVIYWLANFVWDMCNYVVPATLVIIIFICFQQDSYVSSSNLPVLALLLLLYGWSITPLMYPASFIFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTNN--KLSNINEILKSVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFV----SPMSWDLVGRNLFAMAVEGVVFFAITLMIQYRFFIKPRPVNAKLPPVV--------DEDEDVARERQRINEGGR-NDILELKGLTKIYRM--------------------KRKPAVDRLCVGIPPGECFGLLGVNGAGKTTTF 1961

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 382.874 bits (982), Expect = 2.916e-113
Identity = 285/907 (31.42%), Postives = 463/907 (51.05%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFN-----------------AQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-------DLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHY---RCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYF-------YNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESG--IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK  N                  ++++  +  S++G                +   I  H+P+A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG++DT+LEE+F++VADD   ++ ET +  L P    R A +GD ++   PF + +       D++ ++     L  ++   +++L + + L++QQ   L  KR  YAKR++KG FA+++LP + + + +    +V P    P++E+ PW+   +       TF+  +        +  G +  +  L D+         G +   C       ST +        + N  W+      +   SP C+C++   +    IC  P +GG P   R   +SD L NLTG NISDYL+K + ++  K +GG+     N  A  S +                         + LK F  F  K   T +  ++W N+KG+ ++ A+ N+++N +LRS+++  ++  +YGI+  N+P+  ++ ++S+   +   ++V ++I VI A+SF+ ASFV+FLI ER+S +K  Q +SG+ P +YW++NF+WD+  Y++P  ++IIIFI F   SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   N   L  IN+ILK V LIFP F LGRG++D+  N         +  N  V    + + WD+ G  LF++    + ++ + ++I+    I  R +  KL             ED DV  ER+R++   + +D+L +  LTKIY +                     R+ AV+ LC G+  GECFGLLGVNGAGKTTTF
Sbjct: 1064 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKRDNDSSLSSCRNSSSTMSYLKKEDSVSQSSSDAGLGSDHESDTMTIDVSAISNLINKHVPEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGIADTTLEEIFLKVADDTG-VDAETSDGTL-PARRKRYA-FGDHQSCLRPFTEDDAFDTNDSDMDPESRETDYLSGIDGKGSYQL-KSWNLMRQQFTALLWKRLLYAKRSRKGFFAQIVLPAVFVLIALVFSLIVPPFGKYPSLELEPWMYDEQY------TFFSNDA------PDDQGTQALLKALIDK------PGFG-TAFSCSGEEEEWSTQFVSQSVMDLFLNGNWT------MENPSPSCECSSDKRKKMLPIC-PPGAGGLPPFQRRQNTSDILQNLTGRNISDYLVKTYSQIIEKRYGGFSLGASNSPALPSVVG------------------------KLLKIFGAFM-KGLDTKDNVKVWFNNKGWHAVGAFLNVMNNAILRSKLREGEDPASYGITAFNHPLNLTKEQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHMQCISGVKPVIYWLANFVWDMCNYVVPATLVIIIFICFQQDSYVSSSNLPVLALLLLLYGWSITPLMYPASFIFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTNN--KLSNINEILKSVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFV----SPMSWDLVGRNLFAMAVEGVVFFAITLMIQYRFFIKPRPVNAKLPPVV--------DEDEDVARERQRINEGGR-NDILELKGLTKIYRM--------------------KRKPAVDRLCVGIPPGECFGLLGVNGAGKTTTF 1880

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 380.563 bits (976), Expect = 2.105e-112
Identity = 284/916 (31.00%), Postives = 466/916 (50.87%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFN-----------------AQKENFRKGISNSG---------------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-------DLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--CMNPSIYRSTHY---RCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYF-------YNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESG--IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK  N                  ++++  +  S++G                       +   I  H+P+A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG++DT+LEE+F++VADD   ++ ET +  L P    R A +GD ++   PF + +       D++ ++     L  ++   +++L + + L++QQ   L  KR  YAKR++KG FA+++LP + + + +    +V P    P++E+ PW+   +       TF+  +        +  G +  +  L D+         G S ++  C       ST +        + N  W+      +   SP C+C++   +    IC  P +GG P   R   +SD L NLTG NISDYL+K + ++  K +GG+     N           SP           + P N E +  + + ++          +S +W N+KG+ ++ A+ N+++N +LRS+++  ++  +YGI+  N+P+  ++ ++S+   +   ++V ++I VI A+SF+ ASFV+FLI ER+S +K  Q +SG+ P +YW++NF+WD+  Y++P  ++IIIFI F   SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   N   L  IN+ILK V LIFP F LGRG++D+  N         +  N  V    + + WD+ G  LF++    + ++ + ++I+    I  R +  KL             ED DV  ER+R++   + +D+L +  LTKIY +                     R+ AV+ LC G+  GECFGLLGVNGAGKTTTF
Sbjct: 1052 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKRDNDSSLSSCRNSSSTMSYLKKEDSVSQSSSDAGLGSDHESDTMTIGKYKSLTDVSAISNLINKHVPEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGIADTTLEEIFLKVADDTG-VDAETSDGTL-PARRKRYA-FGDHQSCLRPFTEDDAFDTNDSDMDPESRETDYLSGIDGKGSYQL-KSWNLMRQQFTALLWKRLLYAKRSRKGFFAQIVLPAVFVLIALVFSLIVPPFGKYPSLELEPWMYDEQY------TFFSND------APDDQGTQALLKALIDKPGFGTACMEGHSVMKVSCSGEEEEWSTQFVSQSVMDLFLNGNWT------MENPSPSCECSSDKRKKMLPIC-PPGAGGLPPFQRRQNTSDILQNLTGRNISDYLVKTYSQIIEKRYGGFSLGASN-----------SP-----------ALPPNEEVVASINHIKKRLELPQVEYLYSVVWFNNKGWHAVGAFLNVMNNAILRSKLREGEDPASYGITAFNHPLNLTKEQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHMQCISGVKPVIYWLANFVWDMCNYVVPATLVIIIFICFQQDSYVSSSNLPVLALLLLLYGWSITPLMYPASFIFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTNN--KLSNINEILKSVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFV----SPMSWDLVGRNLFAMAVEGVVFFAITLMIQYRFFIKPRPVNAKLPPVV--------DEDEDVARERQRINEGGR-NDILELKGLTKIYRM--------------------KRKPAVDRLCVGIPPGECFGLLGVNGAGKTTTF 1887

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 376.711 bits (966), Expect = 3.651e-111
Identity = 281/912 (30.81%), Postives = 463/912 (50.77%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFN-----------------AQKENFRKGISNSG-----------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-------DLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--CMNPSIYRSTHY---RCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYF-------YNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESG--IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK  N                  ++++  +  S++G                   +   I  H+P+A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG++DT+LEE+F++VADD   ++ ET +  L P    R A +GD ++   PF + +       D++ ++     L  ++   +++L + + L++QQ   L  KR  YAKR++KG FA+++LP + + + +    +V P    P++E+ PW+   +       TF+  +        +  G +  +  L D+         G S ++  C       ST +        + N  W+      +   SP C+C++   +    IC  P +GG P   R   +SD L NLTG NISDYL+K + ++  K +GG+     N           SP           + P N E +  + + ++          +S +W N+KG+ ++ A+ N+++N +LRS+++  ++  +YGI+  N+P+  ++ ++S+   +   ++V ++I VI A+SF+ ASFV+FLI ER+S +K  Q +SG+ P +YW++NF+WD+  Y++P  ++IIIFI F   SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++           N+ILK V LIFP F LGRG++D+  N         +  N  V    + + WD+ G  LF++    + ++ + ++I+    I  R +  KL             ED DV  ER+R++   + +D+L +  LTKIY +                     R+ AV+ LC G+  GECFGLLGVNGAGKTTTF
Sbjct: 1067 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKRDNDSSLSSCRNSSSTMSYLKKEDSVSQSSSDAGLGSDHESDTMTIGLTDVSAISNLINKHVPEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGIADTTLEEIFLKVADDTG-VDAETSDGTL-PARRKRYA-FGDHQSCLRPFTEDDAFDTNDSDMDPESRETDYLSGIDGKGSYQL-KSWNLMRQQFTALLWKRLLYAKRSRKGFFAQIVLPAVFVLIALVFSLIVPPFGKYPSLELEPWMYDEQY------TFFSNDA------PDDQGTQALLKALIDKPGFGTACMEGHSVMKVSCSGEEEEWSTQFVSQSVMDLFLNGNWT------MENPSPSCECSSDKRKKMLPIC-PPGAGGLPPFQRRQNTSDILQNLTGRNISDYLVKTYSQIIEKRYGGFSLGASN-----------SP-----------ALPPNEEVVASINHIKKRLELPQVEYLYSVVWFNNKGWHAVGAFLNVMNNAILRSKLREGEDPASYGITAFNHPLNLTKEQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHMQCISGVKPVIYWLANFVWDMCNYVVPATLVIIIFICFQQDSYVSSSNLPVLALLLLLYGWSITPLMYPASFIFKIPSTAYVVLTSVNLFIGINGSVATFVLELF---------TNNILKSVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFV----SPMSWDLVGRNLFAMAVEGVVFFAITLMIQYRFFIKPRPVNAKLPPVV--------DEDEDVARERQRINEGGR-NDILELKGLTKIYRM--------------------KRKPAVDRLCVGIPPGECFGLLGVNGAGKTTTF 1891

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
Match: Abca1 (ATP-binding cassette, sub-family A (ABC1), member 1 [Source:MGI Symbol;Acc:MGI:99607])

HSP 1 Score: 382.874 bits (982), Expect = 2.302e-113
Identity = 295/927 (31.82%), Postives = 472/927 (50.92%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIP--------NGNIPL--ISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNF-----QRLSRKI------FGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQ-----PQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYF-------YNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 +   ++++  +  S++G                +   I+ H+ +A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG+S+T+LEE+F++VA++ + ++ ET +  L P   NR A +GD ++   PF   D  D N      +S    L+S    +    L+G+ L +QQ + L  KR   A+R++KG FA+++LP + + + +    +V P    P++E+ PW+            +  +   ++      +G +  +N LT         D G  G RCM  +    T   C    ++   SP+P        NGN  +   SP C C++   +    +C     G P    R   ++D L NLTG NISDYL+K +     + L  KI      +GG+   + N  A         P    + D++ Q +      ++    RFL     F      T N  ++W N+KG+ ++ ++ N+++N +LR+ ++  +N   YGI+  N+P+  ++ ++S+   +   ++V ++I VI A+SF+ ASFV+FLI ER+S +K  QF+SG+ P +YW+SNF+WD+  Y++P  ++IIIFI F  +SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   N   L +INDILK VFLIFP F LGRG++D+  N         +  N  V    + L WD+ G  LF++    + ++++ ++I+     R    K K   L      N ED DV  ER+R+      +D+L +  LTKIY                     + R+ AV+ +C G+  GECFGLLGVNGAGK+TTF
Sbjct: 1098 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSCLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVSEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEE-SGVDAETSDGTL-PARRNRRA-FGDKQSCLHPFTEDDAVDPNDSDIDPESRETDLLSGMDGKGSYQLKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWM------------YNEQYTFVSNDAPEDMGTQELLNALT--------KDPG-FGTRCMEGNPIPDTP--CLAGEEDWTISPVPQSIVDLFQNGNWTMKNPSPACQCSSDKIKKMLPVCPPGAGGLP-PPQRKQKTADILQNLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNSQAL--------PPSHEVNDAIKQMKKLLKLTKDSSADRFLSSLGRFM-AGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSQYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTNN--KLNDINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFV----SPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFFIRPRPVKAKLPPL------NDEDEDVRRERQRILDGGGQNDILEIKELTKIY--------------------RRKRKPAVDRICIGIPPGECFGLLGVNGAGKSTTF 1956

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
Match: Abca4 (ATP-binding cassette, sub-family A (ABC1), member 4 [Source:MGI Symbol;Acc:MGI:109424])

HSP 1 Score: 352.058 bits (902), Expect = 7.879e-103
Identity = 272/930 (29.25%), Postives = 446/930 (47.96%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILV---KNFNAQKENFR-------KGISN---------------SGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPA----------KINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--------CMNPSIYRS-------THYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSR-----------KIFGGYQF--LLPNDFAQSSKLIAQSPTWDGIRDSVNQS-----QPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFN-YFYNSNSIVKHEYNA--LQWDIAGEKLFSLFSLSIGWWIVLIIIESG-IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIISQG+L C G+ +FLK  FG G+ L LV   KN  +Q+           KG S                 GD  +L+  +  H+P+AK+      +  F+LP  +     ++ LF  L+E + +L   S+G+SDT LEE+F++V +D            +  E+            ++  Y    +      ++    Q   +     + FN   +L+       Q +  L +KRFH+  R++K   A+++LP   + L + L  +V P    PA+ + PW+                 +Q  F   ++  N++ +  L D L +  R   G   ++        C+N + +++       TH      ++  KW+          SP C C+T    T    C +  +GG P   R   S++ L +LT  NISDYL+K +  L R           + +GG      LP        L+       G+   +N S     +  + E L FLK+ +        T +  ++W N+KG+ ++ ++ N+  N +LR+ +   ++   YGI+V + P+  ++ ++S    L   ++  +AI VI A+SF+ ASFV++LI ER++ +K  QF+SG++P  YW++NFLWDIM Y +   +++ IFI F  ++Y    N  A + LL+ YG A+IP MYP SF    PSTA+V L+  NL +G  ++  TF+L++ E N   L+  N +L+K+ ++FP F LGRG++DL  +    +  +    EY+A   QWD+ G+ L ++    + ++++ ++I+    + R I    +            ED DV  ER+R+ S     D+L++  LTK+Y                    + +   AV+ LC GVR GECFGLLGVNGAGKTTTF
Sbjct: 1127 GDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGGCEGVCSCTSKGFSTRCPTRVDEITEEQVLDGDVQELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDAGAGSMFVGGAQQKREQAGLRHPCSAPTEKLRQYAQAPHTCSPGQVDPPKGQPSPEPEDPGVPFNTGARLIL------QHVQALLVKRFHHTIRSRKDFVAQIVLPATFVFLALMLSIIVPPFGEFPALTLHPWMY---------------GHQYTFFSMDEPNNEH-LEVLADVLLN--RPGFGNRCLKEEWLPEYPCINATSWKTPSVSPNITHL-----FQKQKWTAAHP------SPSCKCSTREKLTMLPECPE-GAGGLPPPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPAIPISGEALVG---FLSGLGQMMNVSGGPVTREASKEMLDFLKHLE--------TTDNIKVWFNNKGWHALVSFLNVAHNAILRASLPRDRDPEEYGITVISQPLNLTKEQLSDITVLTTSVDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDIMNYAVSAGLVVGIFIGFQKKAYTSPDNLPALVSLLMLYGWAVIPMMYPASFLFEVPSTAYVALSCANLFIGINSSAITFVLELFENNRTLLR-FNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDVYAQFGEEYSANPFQWDLIGKNLVAMAIEGVVYFLLTLLIQHHFFLTRWIAEPAREPVFD-------EDDDVAEERQRVMSGGNKTDILKLNELTKVY--------------------SGSSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTF 1981

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
Match: Abca7 (ATP-binding cassette, sub-family A (ABC1), member 7 [Source:MGI Symbol;Acc:MGI:1351646])

HSP 1 Score: 327.791 bits (839), Expect = 1.265e-94
Identity = 276/925 (29.84%), Postives = 459/925 (49.62%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-------------------------NFNAQKENFRKGISN---------------SGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIY-------RSTH----YRCFPEYKNNKWSPIPNGN-IP-LISPECDCNTTGYQ-ICNDPRSGGPPNSYRIMTSS--DKLNNLTGYNISDYLLKNFQRLSRK-----------IFGGYQFLLPN-DFAQSSKLIAQSPTWDGIRDSVNQSQPQN-LEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL--LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNS--NSIVKHEYNA-LQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DR+A+++ G L CCGS +FL+R  G GY L LVK                         N       F +G S+               S  ++L+ ++ H+P A++  +   +   VLP   +    F+ +F  LD++++ L    YG+SDT+LEE+F++V +D  +   +++ +     +L           +   L+  +L  Q              N   ++G+ L  QQ+  L  KRF  A+R+++G+FA+++LP L + L +    +V P    P +++SP +  P               Q++F   +  G+ N +  L         + LGE+G++   PS+          TH    Y   PE   +  S + +GN  P   SP C C+  G + +  D  +G          +   + + NLTG N+SD+L+K +  L R+            +GG+     + D     +++    T   IR ++   QP N L+  R L    ++        N  +IW N+KG+ +M A+ N  +N LL + +        + I+  N+P+  ++ ++S+   LI   ++V ++I V+ A+SF+ ASF + LI+ERI+ +K  Q VSG+   +YW+ NFLWD+  Y++ + I++ IF+AF  ++Y+  +N  A +LLL+ YG +I P MYP SFF S PSTA+VVL   NL +G  ++++TF+L++L  + + L+E++ ILK+VFLIFP F LGRG++D+  N         +   ++ + L+WDI G+ L ++  ++ G   +LI +     NR+    L  S  + +     ED DV  ERER++      DVL + +LTK+Y            +G+        R  AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1002 GDRVAMVAGGSLCCCGSPLFLRRHLGCGYYLTLVKSSQSLVTHDAKGDSEDPRREKKSDGNGRTSDTAFTRGTSDKSNQAPAPGAVPITPSTARILELVQQHVPGAQLVEDLPHELLLVLPYAGALDGSFAMVFQELDQQLELLGLTGYGISDTNLEEIFLKVVEDAHREGGDSRPQL----HLRTCTPQPPTGPEASVLENGELAPQGLAP----------NAAQVQGWTLTCQQLRALLHKRFLLARRSRRGLFAQVVLPALFVGLALFFSLIVPPFGQYPPLQLSPAMYGP---------------QVSFFSEDAPGDPNRMKLL--------EALLGEAGLQ--EPSMQDKDARGSECTHSLACYFTVPEVPPDVASILASGNWTPESPSPACQCSQPGARRLLPDCPAGAGGPPPPQAVAGLGEVVQNLTGRNVSDFLVKTYPSLVRRGLKTKKWVDEVRYGGFSLGGRDPDLPTGHEVVR---TLAEIR-ALLSPQPGNALD--RILNNLTQW-ALGLDARNSLKIWFNNKGWHAMVAFVNRANNGLLHALLPSGPVRHAHSITTLNHPLNLTKEQLSE-ATLIASSVDVLVSICVVFAMSFVPASFTLVLIEERITRAKHLQLVSGLPQTLYWLGNFLWDMCNYLVAVCIVVFIFLAFQQRAYVAPENLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELL--SDQNLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMADAFERLGDKQFQSPLRWDIIGKNLLAM--MAQGPLFLLITLLLQHRNRL----LPQSKPRLLPPLGEEDEDVAQERERVTKGATQGDVLVLRDLTKVY------------RGQ--------RNPAVDRLCLGIPPGECFGLLGVNGAGKTSTF 1851

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Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-------------------------NFNAQKENFRKGISN---------------SGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIY-------RSTH----YRCFPEYKNNKWSPIPNGN-IP-LISPECDCNTTGYQ-ICNDPRSGGPPNSYRIMTSS--DKLNNLTGYNISDYLLKNFQRLSRK-----------IFGGYQFLLPN-DFAQSSKLIAQSPTWDGIRDSVNQSQPQN-LEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL--LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNS--NSIVKHEYNA-LQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DR+A+++ G L CCGS +FL+R  G GY L LVK                         N       F +G S+               S  ++L+ ++ H+P A++  +   +   VLP   +    F+ +F  LD++++ L    YG+SDT+LEE+F++V +D  +   +++ +     +L           +   L+  +L  Q              N   ++G+ L  QQ+  L  KRF  A+R+++G+FA+++LP L + L +    +V P    P +++SP +  P               Q++F   +  G+ N +  L         + LGE+G++   PS+          TH    Y   PE   +  S + +GN  P   SP C C+  G + +  D  +G          +   + + NLTG N+SD+L+K +  L R+            +GG+     + D     +++    T   IR ++   QP N L+  R L    ++        N  +IW N+KG+ +M A+ N  +N LL + +        + I+  N+P+  ++ ++S+   LI   ++V ++I V+ A+SF+ ASF + LI+ERI+ +K  Q VSG+   +YW+ NFLWD+  Y++ + I++ IF+AF  ++Y+  +N  A +LLL+ YG +I P MYP SFF S PSTA+VVL   NL +G  ++++TF+L++L  + + L+E++ ILK+VFLIFP F LGRG++D+  N         +   ++ + L+WDI G+ L ++  ++ G   +LI +     NR+    L  S  + +     ED DV  ERER++      DVL + +LTK+Y            +G+        R  AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1002 GDRVAMVAGGSLCCCGSPLFLRRHLGCGYYLTLVKSSQSLVTHDAKGDSEDPRREKKSDGNGRTSDTAFTRGTSDKSNQAPAPGAVPITPSTARILELVQQHVPGAQLVEDLPHELLLVLPYAGALDGSFAMVFQELDQQLELLGLTGYGISDTNLEEIFLKVVEDAHREGGDSRPQL----HLRTCTPQPPTGPEASVLENGELAPQGLAP----------NAAQVQGWTLTCQQLRALLHKRFLLARRSRRGLFAQVVLPALFVGLALFFSLIVPPFGQYPPLQLSPAMYGP---------------QVSFFSEDAPGDPNRMKLL--------EALLGEAGLQ--EPSMQDKDARGSECTHSLACYFTVPEVPPDVASILASGNWTPESPSPACQCSQPGARRLLPDCPAGAGGPPPPQAVAGLGEVVQNLTGRNVSDFLVKTYPSLVRRGLKTKKWVDEVRYGGFSLGGRDPDLPTGHEVVR---TLAEIR-ALLSPQPGNALD--RILNNLTQW-ALGLDARNSLKIWFNNKGWHAMVAFVNRANNGLLHALLPSGPVRHAHSITTLNHPLNLTKEQLSE-ATLIASSVDVLVSICVVFAMSFVPASFTLVLIEERITRAKHLQLVSGLPQTLYWLGNFLWDMCNYLVAVCIVVFIFLAFQQRAYVAPENLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELL--SDQNLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMADAFERLGDKQFQSPLRWDIIGKNLLAM--MAQGPLFLLITLLLQHRNRL----LPQSKPRLLPPLGEEDEDVAQERERVTKGATQGDVLVLRDLTKVY------------RGQ--------RNPAVDRLCLGIPPGECFGLLGVNGAGKTSTF 1851

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
Match: Abca4 (ATP-binding cassette, sub-family A (ABC1), member 4 [Source:MGI Symbol;Acc:MGI:109424])

HSP 1 Score: 321.627 bits (823), Expect = 1.794e-94
Identity = 242/848 (28.54%), Postives = 409/848 (48.23%), Query Frame = 2

Query:  167 LQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPA----------KINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--------CMNPSIYRS-------THYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSR-----------KIFGGYQF--LLPNDFAQSSKLIAQSPTWDGIRDSVNQS-----QPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFN-YFYNSNSIVKHEYNA--LQWDIAGEKLFSLFSLSIGWWIVLIIIESG-IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            +  +  H+P+AK+      +  F+LP  +     ++ LF  L+E + +L   S+G+SDT LEE+F++V +D            +  E+            ++  Y    +      ++    Q   +     + FN   +L+       Q +  L +KRFH+  R++K   A+++LP   + L + L  +V P    PA+ + PW+                 +Q  F   ++  N++ +  L D L +  R   G   ++        C+N + +++       TH      ++  KW+          SP C C+T    T    C +  +GG P   R   S++ L +LT  NISDYL+K +  L R           + +GG      LP        L+       G+   +N S     +  + E L FLK+ +        T +  ++W N+KG+ ++ ++ N+  N +LR+ +   ++   YGI+V + P+  ++ ++S    L   ++  +AI VI A+SF+ ASFV++LI ER++ +K  QF+SG++P  YW++NFLWDIM Y +   +++ IFI F  ++Y    N  A + LL+ YG A+IP MYP SF    PSTA+V L+  NL +G  ++  TF+L++ E N   L+  N +L+K+ ++FP F LGRG++DL  +    +  +    EY+A   QWD+ G+ L ++    + ++++ ++I+    + R I    +            ED DV  ER+R+ S     D+L++  LTK+Y                    + +   AV+ LC GVR GECFGLLGVNGAGKTTTF
Sbjct:    1 MDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDAGAGSMFVGGAQQKREQAGLRHPCSAPTEKLRQYAQAPHTCSPGQVDPPKGQPSPEPEDPGVPFNTGARLIL------QHVQALLVKRFHHTIRSRKDFVAQIVLPATFVFLALMLSIIVPPFGEFPALTLHPWMY---------------GHQYTFFSMDEPNNEH-LEVLADVLLN--RPGFGNRCLKEEWLPEYPCINATSWKTPSVSPNITHL-----FQKQKWTAAHP------SPSCKCSTREKLTMLPECPE-GAGGLPPPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPAIPISGEALVG---FLSGLGQMMNVSGGPVTREASKEMLDFLKHLE--------TTDNIKVWFNNKGWHALVSFLNVAHNAILRASLPRDRDPEEYGITVISQPLNLTKEQLSDITVLTTSVDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDIMNYAVSAGLVVGIFIGFQKKAYTSPDNLPALVSLLMLYGWAVIPMMYPASFLFEVPSTAYVALSCANLFIGINSSAITFVLELFENNRTLLR-FNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDVYAQFGEEYSANPFQWDLIGKNLVAMAIEGVVYFLLTLLIQHHFFLTRWIAEPAREPVFD-------EDDDVAEERQRVMSGGNKTDILKLNELTKVY--------------------SGSSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTF 773

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BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Match: sp|P41233|ABCA1_MOUSE (Phospholipid-transporting ATPase ABCA1 OS=Mus musculus OX=10090 GN=Abca1 PE=1 SV=4)

HSP 1 Score: 382.874 bits (982), Expect = 1.610e-112
Identity = 295/927 (31.82%), Postives = 472/927 (50.92%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIP--------NGNIPL--ISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNF-----QRLSRKI------FGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQ-----PQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYF-------YNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 +   ++++  +  S++G                +   I+ H+ +A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG+S+T+LEE+F++VA++ + ++ ET +  L P   NR A +GD ++   PF   D  D N      +S    L+S    +    L+G+ L +QQ + L  KR   A+R++KG FA+++LP + + + +    +V P    P++E+ PW+            +  +   ++      +G +  +N LT         D G  G RCM  +    T   C    ++   SP+P        NGN  +   SP C C++   +    +C     G P    R   ++D L NLTG NISDYL+K +     + L  KI      +GG+   + N  A         P    + D++ Q +      ++    RFL     F      T N  ++W N+KG+ ++ ++ N+++N +LR+ ++  +N   YGI+  N+P+  ++ ++S+   +   ++V ++I VI A+SF+ ASFV+FLI ER+S +K  QF+SG+ P +YW+SNF+WD+  Y++P  ++IIIFI F  +SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   N   L +INDILK VFLIFP F LGRG++D+  N         +  N  V    + L WD+ G  LF++    + ++++ ++I+     R    K K   L      N ED DV  ER+R+      +D+L +  LTKIY                     + R+ AV+ +C G+  GECFGLLGVNGAGK+TTF
Sbjct: 1098 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSCLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVSEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEE-SGVDAETSDGTL-PARRNRRA-FGDKQSCLHPFTEDDAVDPNDSDIDPESRETDLLSGMDGKGSYQLKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWM------------YNEQYTFVSNDAPEDMGTQELLNALT--------KDPG-FGTRCMEGNPIPDTP--CLAGEEDWTISPVPQSIVDLFQNGNWTMKNPSPACQCSSDKIKKMLPVCPPGAGGLP-PPQRKQKTADILQNLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNSQAL--------PPSHEVNDAIKQMKKLLKLTKDSSADRFLSSLGRFM-AGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSQYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTNN--KLNDINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFV----SPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFFIRPRPVKAKLPPL------NDEDEDVRRERQRILDGGGQNDILEIKELTKIY--------------------RRKRKPAVDRICIGIPPGECFGLLGVNGAGKSTTF 1956

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BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Match: sp|O95477|ABCA1_HUMAN (Phospholipid-transporting ATPase ABCA1 OS=Homo sapiens OX=9606 GN=ABCA1 PE=1 SV=3)

HSP 1 Score: 375.17 bits (962), Expect = 6.226e-110
Identity = 292/929 (31.43%), Postives = 472/929 (50.81%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWS--PIP--------NGNIPL--ISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNF-----QRLSRKI------FGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQ-----PQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYF-------YNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 ++  ++++  +  S++G                +   I+ H+ +A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG+S+T+LEE+F++VA++ + ++ ET +  L P   NR A +GD ++   PF   D  D N      +S    L+S    +    ++G+ L +QQ + L  KR   A+R++KG FA+++LP + + + +    +V P    P++E+ PW+            +  +   ++       G    +N LT         D G  G RCM  +    T  +   E    +W+  P+P        NGN  +   SP C C++   +    +C     G P    R   ++D L +LTG NISDYL+K +     + L  KI      +GG+   + N  A         P    + D++ Q +      ++    RFL     F      T N  ++W N+KG+ ++ ++ N+++N +LR+ ++  +N  +YGI+  N+P+  ++ ++S+   +   ++V ++I VI A+SF+ ASFV+FLI ER+S +K  QF+SG+ P +YW+SNF+WD+  Y++P  ++IIIFI F  +SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   N   L  INDILK VFLIFP F LGRG++D+  N         +  N  V    + L WD+ G  LF++    + ++++ ++I+     R      K S L      N ED DV  ER+R+      +D+L +  LTKIY                     + R+ AV+ +C G+  GECFGLLGVNGAGK++TF
Sbjct: 1098 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVSEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEE-SGVDAETSDGTL-PARRNRRA-FGDKQSCLRPFTEDDAADPNDSDIDPESRETDLLSGMDGKGSYQVKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWM------------YNEQYTFVSNDAPEDTGTLELLNALT--------KDPG-FGTRCMEGNPIPDTPCQAGEE----EWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSSDKIKKMLPVCPPGAGGLP-PPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNTQAL--------PPSQEVNDAIKQMKKHLKLAKDSSADRFLNSLGRFMT-GLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTDN--KLNNINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFV----SPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFFIRPRPVNAKLSPL------NDEDEDVRRERQRILDGGGQNDILEIKELTKIY--------------------RRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTF 1956

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BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Match: sp|O35600|ABCA4_MOUSE (Retinal-specific phospholipid-transporting ATPase ABCA4 OS=Mus musculus OX=10090 GN=Abca4 PE=2 SV=1)

HSP 1 Score: 352.058 bits (902), Expect = 5.511e-102
Identity = 272/930 (29.25%), Postives = 446/930 (47.96%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILV---KNFNAQKENFR-------KGISN---------------SGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPA----------KINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--------CMNPSIYRS-------THYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSR-----------KIFGGYQF--LLPNDFAQSSKLIAQSPTWDGIRDSVNQS-----QPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFN-YFYNSNSIVKHEYNA--LQWDIAGEKLFSLFSLSIGWWIVLIIIESG-IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIISQG+L C G+ +FLK  FG G+ L LV   KN  +Q+           KG S                 GD  +L+  +  H+P+AK+      +  F+LP  +     ++ LF  L+E + +L   S+G+SDT LEE+F++V +D            +  E+            ++  Y    +      ++    Q   +     + FN   +L+       Q +  L +KRFH+  R++K   A+++LP   + L + L  +V P    PA+ + PW+                 +Q  F   ++  N++ +  L D L +  R   G   ++        C+N + +++       TH      ++  KW+          SP C C+T    T    C +  +GG P   R   S++ L +LT  NISDYL+K +  L R           + +GG      LP        L+       G+   +N S     +  + E L FLK+ +        T +  ++W N+KG+ ++ ++ N+  N +LR+ +   ++   YGI+V + P+  ++ ++S    L   ++  +AI VI A+SF+ ASFV++LI ER++ +K  QF+SG++P  YW++NFLWDIM Y +   +++ IFI F  ++Y    N  A + LL+ YG A+IP MYP SF    PSTA+V L+  NL +G  ++  TF+L++ E N   L+  N +L+K+ ++FP F LGRG++DL  +    +  +    EY+A   QWD+ G+ L ++    + ++++ ++I+    + R I    +            ED DV  ER+R+ S     D+L++  LTK+Y                    + +   AV+ LC GVR GECFGLLGVNGAGKTTTF
Sbjct: 1127 GDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGGCEGVCSCTSKGFSTRCPTRVDEITEEQVLDGDVQELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDAGAGSMFVGGAQQKREQAGLRHPCSAPTEKLRQYAQAPHTCSPGQVDPPKGQPSPEPEDPGVPFNTGARLIL------QHVQALLVKRFHHTIRSRKDFVAQIVLPATFVFLALMLSIIVPPFGEFPALTLHPWMY---------------GHQYTFFSMDEPNNEH-LEVLADVLLN--RPGFGNRCLKEEWLPEYPCINATSWKTPSVSPNITHL-----FQKQKWTAAHP------SPSCKCSTREKLTMLPECPE-GAGGLPPPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPAIPISGEALVG---FLSGLGQMMNVSGGPVTREASKEMLDFLKHLE--------TTDNIKVWFNNKGWHALVSFLNVAHNAILRASLPRDRDPEEYGITVISQPLNLTKEQLSDITVLTTSVDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDIMNYAVSAGLVVGIFIGFQKKAYTSPDNLPALVSLLMLYGWAVIPMMYPASFLFEVPSTAYVALSCANLFIGINSSAITFVLELFENNRTLLR-FNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDVYAQFGEEYSANPFQWDLIGKNLVAMAIEGVVYFLLTLLIQHHFFLTRWIAEPAREPVFD-------EDDDVAEERQRVMSGGNKTDILKLNELTKVY--------------------SGSSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTF 1981

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Match: sp|Q8IZY2|ABCA7_HUMAN (Phospholipid-transporting ATPase ABCA7 OS=Homo sapiens OX=9606 GN=ABCA7 PE=1 SV=3)

HSP 1 Score: 343.969 bits (881), Expect = 3.146e-99
Identity = 274/915 (29.95%), Postives = 453/915 (49.51%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-------------------NFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAK---INEETKNEKL--------IPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGN-IP-LISPECDCNTTGYQ-ICND--PRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRK-----------IFGGYQFLLPNDFAQSSKLIAQS---------PTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNS--NSIVKHEYNA-LQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRN-----TEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DR+A+++ G+L CCGS +FL+R  G GY L LVK                   +   +K+N  +G      +LL  ++  +P A++  E   +   VLP   ++   F+ LF  LD  +  L    YG+SDTSLEE+F++V ++ A    + + +  + L        +   L        +EN EP     + +Q +  D         R    ++G+ L +QQ+  L +KRF  A+R+++G+FA+++LP L + L +    +V P    PA+ +SP             T Y    Q++F   +  G+      L   L+        E+G+    P +  S+H    PE        + +GN  P   SP C C+  G + +  D    +GGPP    +  S + + NLTG N+SD+L+K + RL R+            +GG+     +    S + + +S         P   G  D             R LK    + + S    +  +IW N+KG+ SM A+ N  SN +LR+ +        + I+  N+P+  ++ ++S+   +   ++V ++I V+ A+SF+ ASF + LI+ER++ +K  Q + G++P +YW+ NFLWD+  Y++P  I+++IF+AF  ++Y+   N  A +LLL+ YG +I P MYP SFF S PSTA+VVL   NL +G   +++TF+L++   + + L+E++ ILK+VFLIFP F LGRG++D+  N         +   ++ + L+W++ G+ L +           ++I     +   +  + ++  L +  +R+      ED DV  ERER+       DVL + NLTK+Y            +G+        R  AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1005 GDRVAVVAGGRLCCCGSPLFLRRHLGSGYYLTLVKARLPLTTNEKADTDMEGSVDTRQEKKNGSQGSRVGTPQLLALVQHWVPGARLVEELPHELVLVLPYTGAHDGSFATLFRELDTRLAELRLTGYGISDTSLEEIFLKVVEECAADTDMEDGSCGQHLCTGIAGLDVTLRLKMPPQETALENGEPAGSAPETDQGSGPDA------VGR----VQGWALTRQQLQALLLKRFLLARRSRRGLFAQIVLPALFVGLALVFSLIVPPFGHYPALRLSP-------------TMYGA--QVSFFSEDAPGDPGRARLLEALLQ--------EAGLE--EPPVQHSSHRFSAPEVPAEVAKVLASGNWTPESPSPACQCSRPGARRLLPDCPAAAGGPPPPQAVTGSGEVVQNLTGRNLSDFLVKTYPRLVRQGLKTKKWVNEVRYGGFSLGGRDPGLPSGQELGRSVEELWALLSPLPGGALD-------------RVLKNLTAWAH-SLDAQDSLKIWFNNKGWHSMVAFVNRASNAILRAHLPPGPARHAHSITTLNHPLNLTKEQLSEGALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLMGGLSPTLYWLGNFLWDMCNYLVPACIVVLIFLAFQQRAYVAPANLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINGSMATFVLELF--SDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMADAFERLGDRQFQSPLRWEVVGKNLLA-----------MVIQGPLFLLFTLLLQHRSQLLPQPRVRSLPLLGEEDEDVARERERVVQGATQGDVLVLRNLTKVY------------RGQ--------RMPAVDRLCLGIPPGECFGLLGVNGAGKTSTF 1837

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BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Match: sp|P78363|ABCA4_HUMAN (Retinal-specific phospholipid-transporting ATPase ABCA4 OS=Homo sapiens OX=9606 GN=ABCA4 PE=1 SV=3)

HSP 1 Score: 333.954 bits (855), Expect = 7.189e-96
Identity = 269/919 (29.27%), Postives = 441/919 (47.99%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILV---KNFNAQKENFR-------KGISNS---------------GD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHK--------------LLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKE-NQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYR--STHYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSR-----------KIFGGYQF--LLPNDFAQSSKLIAQSPTWDGIRDSVNQ--SQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYN---SNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESG-IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAII+QG+L C G+ +FLK  FG G  L LV   KN  +Q++          KG S +               GD  +L+  +  H+P+AK+      +  F+LP  +     ++ LF  L+E + +L   S+G+SDT LEE+F++V +D           +   +N+N          + P L   +   Q   D ++ S      H               L  G  L+ Q +  L +KRF +  R+ K   A+++LP   + L + L  ++ P    PA+ + PW+   +    +++    ++   L   + N+ G  N    L +    EY          C N + ++  S        ++  KW+ +        SP C C+T    T    C +  +GG P   R   S++ L +LT  NISD+L+K +  L R           + +GG      LP        L+        I +      ++  + E   FLK+ +        T +  ++W N+KG+ ++ ++ N+  N +LR+ +   ++   YGI+V + P+  ++ ++S+   L   ++  +AI VI ++SF+ ASFV++LI ER++ SK  QF+SG++P  YWV+NFLWDIM Y +   +++ IFI F  ++Y   +N  A + LL+ YG A+IP MYP SF    PSTA+V L+  NL +G  ++  TFIL++ E N   L+  N +L+K+ ++FP F LGRG++DL  +       +    +H  N   WD+ G+ LF++    + ++++ ++++    +++ I    K   +        ED DV  ER+R+ +     D+LR+  LTKIY                          AV+ LC GVR GECFGLLGVNGAGKTTTF
Sbjct: 1127 GDRIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTCSCSSKGFSTTCPAHVDDLTPEQVLDGDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGPLFAGGAQQKRENVN---------PRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPECPGPQLNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPALTLHPWIYGQQYTFFSMDEPGSEQFTVLADVLLNKPGFGNRC--LKEGWLPEYP---------CGNSTPWKTPSVSPNITQLFQKQKWTQVNP------SPSCRCSTREKLTMLPECPE-GAGGLPPPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPVVPITGEALVGFLSDLGRIMNVSGGPITREASKEIPDFLKHLE--------TEDNIKVWFNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITVISQPLNLTKEQLSEITVLTTSVDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSVSAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINSSAITFILELFENNRTLLR-FNAVLRKLLIVFPHFCLGRGLIDLALSQAVTDVYARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTLLVQRHFFLSQWIAEPTKEPIVD-------EDDDVAEERQRIITGGNKTDILRLHELTKIY--------------------PGTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTF 1982

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BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Match: A0A1S3JVH4 (LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 1-like OS=Lingula unguis OX=7574 GN=LOC106176500 PE=4 SV=2)

HSP 1 Score: 488.034 bits (1255), Expect = 4.999e-147
Identity = 323/943 (34.25%), Postives = 494/943 (52.39%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-------------------------NFNAQKENFRKGISNSGDK----------------------------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPA--KINEETKNEKL--------IPDNLNRIAVYGD----IENQEPFLDLEDLNQQAFVD----KSLISLNFNR---------NHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMP-KSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIP--NGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQ--SSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFN-NLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYF-------YNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            DRIAIIS GKL+CCGSS+FLK K+G GY L +VK                          F ++K+     +S++G K                            +  F++  IP AK+  +  T+  F LP+  +++  F  LF  L+  +  L   SYG+SDT+LEEVF++VA++     +NEE     L        I   + R++         +  +P L++ D N+    D     S+ S+  +          +HK+  G    K Q + L +KRFH+ +R+ KG   E++LP + + + +   K++  ++  PA+E+ PW+ +P    + +L  FY               N    + L D LE + RS LG  G RCMN S+Y    Y C P     +W+P P   GN  L SP C C+T GYQ C  P +GGP  S R+M ++D+L N+TG N+SD+L+K  +   ++ +GGY     N   Q  SS+L       D +  +VN  QP  L     +    +   K+    N  ++W N+KG+A+M +Y N ++N++LRS++   ++   YGI+V+N+P+A +  +I +   N   + V +AI VI A+SFI ASFV++LI+ER+S SK  QFVSG+N   YWVS+  WDIM Y + +++ I++F+AF+ +SY+   NA   +LLL  YG A+IP M+PF++    PSTAFV L   N+ +G  +T+ST++L+    + E L +IN +L++VFLI P + LGRG++D+  N         Y + + VK   +  +WD  G  LF+L      W+   ++IE     +  C    +S    ++  + ED DV  ER R  S +   D+LRV NLTK++                 + + K + VAV+ LCF V +GECFGLLGVNGAGKTTTF
Sbjct:  797 DRIAIISLGKLRCCGSSLFLKNKYGSGYYLTMVKANSDEKPADRPVTALSNRTVSDIKAQFVSEKDEGVADMSDTGSKSEHSDSDQSATPPPEYEDPVPCVKDSSDVAVFVQKFIPSAKLVEDMGTELCFQLPEEGTHTGAFEALFRALESNLTKLGITSYGISDTTLEEVFLKVAEESGVDDVNEEQTRNALERYTEGGKIARPVTRLSFRKKKLDFFKKSKPVLNISDTNELVDSDFEDADSVASMPVSEVSTAQGGAGSHKV-TGLAHTKDQFLALFVKRFHHVRRSYKGFVCEILLPAIFVCIAMIFTKIIPVIKENPALELQPWMYVPITGTNPHLTVFYT--------------NDAPGSMLADSLERQIRSPLG-IGTRCMNSSVYSIRGYPCTPASSAERWTPSPAVTGNTSLDSPSCSCDT-GYQTC-PPGAGGPLGSSRVMDNTDRLVNMTGRNVSDWLVKTMEDYKKRRYGGYSLGERNQLVQLNSSQLYQ---VVDRLSRAVNNGQPV-LNGNESIWSDIDALIKNVAVQNNVKVWFNNKGWAAMASYMNAMNNVILRSKLPPGKDPAQYGITVSNHPMAPTNKQIERDTLNSAWISVLVAIGVIFAMSFIPASFVLYLIEERVSNSKHLQFVSGVNRVTYWVSHLAWDIMNYSVSMVLCILLFLAFNERSYVSPTNAPCLVLLLFLYGWAMIPMMFPFNYLFKVPSTAFVALACVNVFLGVTSTLSTYVLEFFSDDQE-LVQINTVLRQVFLILPHYCLGRGLIDMAANQLIADVAGIYVAGTAVK---DPFEWDQVGRNLFALAVSGAAWFGFTLLIEY----KFFCTSRLSSNENAVD--DNEDIDVARERRRAMSAEARSDILRVENLTKVF-----------------HKRRKGKFVAVDRLCFSVPKGECFGLLGVNGAGKTTTF 1690

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BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Match: V4ABB8 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_212836 PE=4 SV=1)

HSP 1 Score: 453.366 bits (1165), Expect = 2.403e-134
Identity = 323/920 (35.11%), Postives = 488/920 (53.04%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN-----FNAQKENFRKGI--------------------------SNSGD----KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNF-------NRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNN----KWSPIP--NGNIPLISPECDCNTTGYQICNDPR-SGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLS--------RKIFGGYQFLLPNDFAQ--SSKLI----AQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLI-LLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEY------NALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            DRIAIIS GKL CCGSS+FLK KFG GY L LVK       N   ++   G+                          S +G     ++  F++ ++ +A++  +  T+  + LP    +S  F  LF  L+     L   S+GLSDTSLEEVF+ VAD+    N +   ++   +N  +   +  + N+   ++  +L +    + S+ S          N   + L G+ L+  Q + L IKRFH+ +R+KKG   E+ILP   + L IA   ++ PL + P +E+ PWL +PK    NL  FY               N N  + L + LE    S     G RCMNP +Y    Y C  E  +N    KW+  P   GN+ + SP CDC + G+  C  P+ +GGP  S   + ++D L N+T  NISD+LL +    S           + G  F   N  A   SS+++      S   +G +  VN S   +++ L           +   T N +++W N+KG+AS  +Y N+L+N++LRS++  +++  +YGI+  N+P+A ++ + S    L  ++++ +AI VI A+SFI ASF+IFLI+ER+S SK  QFVSGINP +YW+S F WD++ Y++P  + ++IF+AFD +SY+ + N    + LL  YG AIIP MYPFS   S  S+AFV ++  N+ +G ++T+STFI+++LE + + L +IN ILK VFL+ P + LGRG++D+  N       + K  +      N L WD+ G  LFSL  L I ++I+  +IE           +K  Y+K  E  N ED DV+ E++R+ S +  +DVL + NL+K++                 Y   + +  AV+NLC GV  G+CFGLLGVNGAGKTTTF
Sbjct: 1089 DRIAIISHGKLCCCGSSLFLKSKFGSGYYLTLVKQDGNGAVNVDDDDDEDGLKKALNDDDGLRPSTADVDEGFGESNGSTTGSLSVGRITGFVQKYVKNAQLVEDNSTELCYQLPTEAMSSGDFEALFTQLERSHHELGIDSFGLSDTSLEEVFLAVADE---TNVDDLTDEATRNNFRKKKKFNFLRNRRSRIEHTELVEDTDDNVSIASSTLENRVGFANSGVQKLHGWSLIFNQFLALFIKRFHHVRRSKKGFVCEIILPAGFVALAIAFSLILPPLVTEPPLELHPWLYVPKKSEPNLYMFY--------------SNDNPRSTLANSLEQALLSK-PWVGTRCMNPDVYSIDGYPC--EGSSNSQYLKWTERPKMTGNLTIDSPSCDC-SRGFPDC--PKGAGGPTPSMSYLPTTDYLYNMTARNISDWLLAHIPSFSICFDMFIFHYRYAGISFGDINPLADVNSSQIVDIINRLSEAANGGQPIVNNSFLTDIDTLA----------RGFLTRNVAKVWYNNKGWASSVSYMNVLNNMILRSKLPANKDPADYGITTINHPMAYNQKQFSAEAILTSVIDLIVAICVIFAMSFIPASFLIFLIEERVSDSKHMQFVSGINPTIYWISTFAWDMVNYLVPATLCVLIFLAFDQESYVSASNFPCLLALLFLYGWAIIPLMYPFSRLFSVSSSAFVTISCANVFLGVVSTLSTFIVELLEQSDKELADINTILKSVFLVLPHYCLGRGLIDMTRNQL--QYDLTKQFFPDAKPSNILAWDLVGRNLFSLAMLGIFFFILNWLIEYRFF-------IKPRYVKESEDTN-EDIDVSREKQRVLSGEADNDVLVLKNLSKVF-----------------YGARRKKLKAVDNLCVGVPRGQCFGLLGVNGAGKTTTF 1948

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Match: N1PB02 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_226736 PE=4 SV=1)

HSP 1 Score: 443.736 bits (1140), Expect = 4.893e-131
Identity = 310/898 (34.52%), Postives = 472/898 (52.56%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN---------FNAQKENFRKGISNSGD-KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNE-KLIPDNLNRIAVYG-----------------DIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMP-KSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNG-NIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSS-----KLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFN-NLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNAL---------QWDIAGEKLFSLFSLSIGWWIVLIIIESG--IVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAII+QGKL C GSS+FLK  FG GY L LVK+          + + EN  +   N+G+     FI   +P+A +      + ++ LP + S++  F  LF +LD  + +L  LSYG+SDT+LEEVF++VA++  + N  ++ + +   + L    +Y                  D E+ E  LD  D N  + V  + IS N   ++K+  G  L+ +Q + + IKRF+Y +R+KK   ++                        PAMEI PWLM P K +  +L TF+          +N L ++     + D L  +        G+RCM+P +Y    +RC  + ++++WS +    + P    EC C + GYQ C    +G   + Y ++ ++D++ N+TG NISD++LK  Q   ++ +GG  F   ND  +++      + AQ  T     D+ N + P  +  L       E   K+  T   ++IW N+KGY SM AY NI++NL+LR+ +    +   YGIS+ N+P+  + +++  +     +++V +++ VI A+  I ASFV+FLI+ER+SGSK  QFVSG+NP VYWV+NF WD++ Y++  I+ I+IF+AF   +Y+   NA   + LL+ YG A  P MYP S F + PS+AFV+L   N+ +G I+T+STFIL+      + L EIN I+ KVFL+ P + LGRG++D+        N +V   +  L          WDI G  L SL  L + ++ + I IE    I +       K      +E  + ED DV  ERER++    S D+L +  LTK+Y                + +KNK    AV+ L  GV  GECFGLLGVNGAGKTTTF
Sbjct: 1093 GDRIAIINQGKLCCVGSSLFLKSNFGGGYYLTLVKDERKGDSASTSDVKVENATED-GNAGEISTTAFIMERVPEAVLVESIGIEMTYQLPNDKSHTASFEKLFRDLDAHLSSLGLLSYGVSDTTLEEVFLKVANESEEANHLSEEDVRQGTERLTDGGMYARPVTRLSFRKRNFFASKDRESNE-LLD-ADGNPDSAVSTASISCNGTGSYKV-TGLSLIPRQFLAIFIKRFNYLRRSKKAFISQE-----------------------PAMEIHPWLMSPSKLQDSHLFTFF----------SNDLPSEAWTQAIEDLLTQK-----PGLGVRCMDPDVYSLKGFRCV-DAEDSQWSNVEEDFDEP---EECSCES-GYQRCPKGAAGAEASKY-LLPTTDEMYNMTGRNISDWILKTSQEYIKRRYGGLTFGERNDLLRANDTEVDSIFAQLATAAAGDDTNNVTLPGLILDL-------ENLIKNIATKRNAKIWFNNKGYVSMVAYMNIMNNLVLRAHLPPDTDPSRYGISLINHPMNRTSSQLYAYTLKASIVDVMISVSVIFAMCLIPASFVLFLIEERVSGSKHLQFVSGVNPVVYWVANFTWDMLNYLVSGILCILIFVAFQQNAYVSQTNAPCLVSLLLLYGWAATPMMYPASHFFNVPSSAFVILGCMNIFLGIISTLSTFILEAF--MEQELDEINAIIMKVFLVLPHYCLGRGLIDM------TRNQLVADIFENLGETFFQSPFTWDIVGRNLLSLSILGVFFFFLNICIEYKFWIYSMKCISPCKEQIPVNVEETDEEDIDVVRERERVTLGAASGDILTLEGLTKVYK---------------SPLKNKGHR-AVDRLSVGVHSGECFGLLGVNGAGKTTTF 1911

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BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Match: A0A2T7NPT0 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_16419 PE=4 SV=1)

HSP 1 Score: 413.69 bits (1062), Expect = 1.319e-120
Identity = 287/826 (34.75%), Postives = 446/826 (54.00%), Query Frame = 2

Query:  161 KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINE---ETKNEKL--------IPDNLNRIAVYGDIEN---------QEPFLDLEDLNQQAFVDKSLISLNFNRNHKL-LRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNN-KWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSV-NQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSW-NYGISVTNYPIADSETKISQFNNL-ILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYF---YNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            +L  FI+ ++PDAK+  +   +  F +P + + S   + LF  L++   +L   SYG+SDTSLEEVF++V ++ +   E   E    KL         P  ++R++    I N         +E   D +D + +     +     F+   K+ + G  L   QII L IKRFH+ +R+KKG   E +LP   + L +    +  P+E +P +E+ PW   P     +L  F+  +N          G+   +      L S +       G RCMNP +Y  + Y C      +   SP   G+     P C C++ G+Q C D  +GGP  + R +  +D L N+TG +I D+LLK  ++   + FGG+ F    D    S+L A   T   I D V   +      P   ++  +EFFN +    N +++W N+K +AS  AY + L+N++LRS +  S+  W +YGI   N+P+  ++ ++ + + +   + V +AI VI A+SF+ ASFV+FLI+ER+S SK  QFVSGINP +YWV+NF+WD+M Y+IP ++ I IF+AF  ++Y+ ++NA   + LL  YG AI P MYPFS   S PS+AFV L+  N+ +GT++T++TFIL++L      L+EIN ILK+VFL+ P + LGRG++D+  N       +   V   Y   QW+  G  LF+LF L I ++I+  +IE      I   K ++      + +  ED DV  ER+R+ S     DV+++ NLTK+  +        G        + + ++ AV++LC G+ +G+CFGLLGVNGAGKTTTF
Sbjct: 1189 RLRAFIEKYVPDAKLVEDNSMEVCFQIPDSSAKSGCLTTLFAELEKFCHHLGVSSYGISDTSLEEVFLKVTEENSNAEEDKDENTRRKLDVITDHGRYPRPVSRLSFRSKIRNTFFSNHVDAKELLDDTDDTSSEGSSASAEEGNTFSGAGKIQVTGRQLTLSQIIALLIKRFHHVRRSKKGFICEFVLPAAFVCLAMVFSLIQPPVEDMPPLELHPWHYQPTKGDSSLYIFFSNDNP-------SQGHARKLEETL--LNSPFH------GARCMNPDVYTISGYSCLSSDTGSFSASPKLTGDPSKDFPACSCDS-GFQRCPD-GAGGPEPARRFLPVNDNLYNMTGRDIPDWLLKTMEQYMIRRFGGFSF---GDENPLSRLNASQMT-AAISDIVLAVTNGTTTLPDSVVRDAEEFFNNAVVQDN-AKVWFNNKAWASSVAYMSSLNNIILRSYLPPSK--WQDYGIVTVNHPMNFTKGQLDRESIMNSAVNVVVAICVIFAMSFVPASFVLFLIEERVSSSKHLQFVSGINPTIYWVTNFMWDMMNYLIPAVLCIFIFLAFGKEAYVSAQNAPCLVALLFLYGWAITPMMYPFSRLFSVPSSAFVALSCVNVFLGTVSTLATFILELLGREDPDLEEINTILKQVFLLLPHYCLGRGLIDMATNQLIVDLAARYGVTCTYKMFQWNYVGRNLFALFMLGILFFIINWLIEYKFF--ITWSKTEH------KSQEVEDVDVAKERQRVLSGGADGDVMKLENLTKVCLL--------GS-------RQERQDEAVDHLCVGIPQGQCFGLLGVNGAGKTTTF 1967

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BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Match: A0A1D1VFB8 (Uncharacterized protein OS=Ramazzottius varieornatus OX=947166 GN=RvY_09881 PE=4 SV=1)

HSP 1 Score: 408.683 bits (1049), Expect = 8.082e-119
Identity = 315/887 (35.51%), Postives = 463/887 (52.20%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFL---------DLEDLNQQAFVDKSLISL-----------NFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVN-PLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPL-ISPECDCNTTGYQICNDPR-SGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSK------TMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLILLE----VTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFF-NYFYNSNSIVKHEYN--ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            SDRIA+I+ G+L C GS VFLK +FG GY L +VK+ +   E          ++L +FI++ +P+A +     ++ SF+LP +     +F  LF  LD  +  LN  SYG+ DTSLEEVF+RV D  +  N + K+E L     N +A  G +                 LED    A    S +S            + N   K + G  L  QQ+  + IKRFH  +R+KK  F E++LP L + L + +  L   PLE  PA+E++PWL  P +       F+  E         Q G+ N+   L +  E          G RCM  S        C P  KN+     P   +    +P C C+  G QIC  PR +GGP     ++ ++D L N+TG N+SD+L K  +      +GGY F   + FAQ +  + +    DG+R  V Q+Q QN EP+      Q  +   +K      T +  ++W N++G+AS  +Y N ++N++LRSR+K   + + YGI   N+P+  +E    Q  + I+ E    +  A+ +I A+SF+ ASFV+FLIDER+SG+K  QF + + P++YWVS ++WDI+ Y +   I I+IF+AF+ Q+Y+ S NA A I LL  YG A IP MY  S+    PS+AFV L   NL +G ++TI+ FIL++L+ + E L+E+  IL+KVFL+ P + LGRG+MDL   N   N  S    E +    +W   G  +F +    I ++++ I+IE     R    K K   +    +RN ED DV  ER R+++    + VL   NL+K +                   K K   +AV+N+ F V +GECFGLLGVNGAGKTTTF
Sbjct: 1119 SDRIAVIADGRLVCSGSPVFLKSRFGCGYYLTVVKSSSDTNE----------EELGRFIRAFVPEAVLIENVGSEMSFILPTDVKKEGRFEALFEALDTMLARLNISSYGIRDTSLEEVFLRVMD--SHNNHKEKDEDLA----NGVASEGFLAKMRRRYRGGGNPVDGALEDPAALATSGGSTLSSQSQSVALDDWDHINVAIKRVYGPRLALQQMKAMHIKRFHNLRRSKKSFFCEILLPALFVCLAMVVTLLTPVPLEQ-PALELTPWLYGPPNY-----MFFADE---------QPGSPNTSVLLRNMYEGP------GIGTRCMKGSPVSGKS--CIPTIKNDISQLTPEFPVSRNATPSCSCDVGG-QIC--PRNAGGPMPPCMLLNTTDWLCNMTGRNVSDWLTKTAKNYDSTRYGGYSFGEVDTFAQFNFTVWK----DGLRAMVEQAQ-QNEEPVPHENGLQGRWRNFAKLLSGMFTKDNIKVWFNNRGWASSVSYTNAINNVILRSRLKAGADPYQYGIMAVNHPLNRTE---EQMEDQIIKESAKSLLHAVCIIFAMSFVPASFVMFLIDERVSGAKNLQFTAKVKPWLYWVSTYIWDIVNYSLTACICIMIFLAFNEQAYVSSTNAPALICLLFLYGFAAIPMMYIPSYLFKVPSSAFVALACANLFLGLVSTITVFILELLD-DVE-LQEVAAILRKVFLVLPHYCLGRGLMDLAITNVKANVFSRFGQEVDDHPFEWTFMGRNVFCMMVQGIVFFLLTILIEY----RFFV-KPKRVTVASEVLRN-EDRDVAAERARVAAGHADNSVLTCRNLSKAFK------------------KRKQTYLAVDNISFAVEKGECFGLLGVNGAGKTTTF 1929

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
Match: ENSAMXT00000016919.2 (pep primary_assembly:Astyanax_mexicanus-2.0:8:9912642:9956080:1 gene:ENSAMXG00000016432.2 transcript:ENSAMXT00000016919.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 385.185 bits (988), Expect = 3.109e-114
Identity = 289/927 (31.18%), Postives = 477/927 (51.46%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG---------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQ--EPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWS--PIPNGNIPLI----------SPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKI-----------FGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQ-NLEPL---RFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN----ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK   G GY L LVK                 ++  + +   +  S++G                 +   I  H+P+A+M  +   + +++LP   +    F  LF ++D+ + +L   SYG+SDT+LEE+F++VA+D + ++ E  ++   P    R   +G       +P    D  D N+     +S     +S +  +    ++G+ L +QQ + L  KRF YA+R++KG FA+++LP + + + +    +V P    P++ + PW+                E+Q+ F I++      S    T RL +      G  G RCM           C     ++ WS   +P   + ++          SP C+C++ G +     C     G PP   +I +  D L NLTG NISDYL+K + ++  K            +GG+        A+S++++   P  + I D++ + +   NLE +   RFLK    F N    T N  +IW N+KG+ S+ A+ N+++N +LR+ +   ++   YGI+  N+P+  ++ ++SQ   +   ++V ++I VI A+SF+ ASFV+FLI ER++ +K  QF+SG+ P++YW++NF+WD+  Y++P  ++I+IF+ F  ++Y+ + N     LLL+ YG +I P MYP SF    PSTA+VVL + N+L+G   ++STF+L++   N   +  INDILK V LIFP F LGRG++D+  N    ++++ +   N      +WD+ G+ LF++    + ++I+ ++I+     +       N+ L  I     ED DV  ER+R+ S     D+L +  LTK+Y                     + ++ AV+ LC G+  GECFGLLGVNGAGKTTTF
Sbjct:  993 GDRIAIISHGKLCCVGSSLFLKTHLGTGYYLTLVKKEPEASLSSCRNSSSTVSYVKKDDEASESSSDAGLGSDHESDAATAIDISLISGLIIKHVPNARMVEDLGHEITYILPYESAKDGAFVELFHDMDDHLADLGISSYGVSDTTLEEIFLKVAED-SGVDTEILSDGTFPIRRRRRHAFGADHQSCLKPLTEDDRYDGNESEVDPESRETDYLSGSDGKGSYQIQGWSLKRQQFLALLWKRFLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLALQPWMY---------------EDQVTF-ISDDAPEDAS----TQRLLAALMEGPG-FGTRCMEGEPIPDAP--C--TIGDDDWSIPEVPESVLEVLMSQNWTMDNPSPACECSSDGKKKMLPECPASAGGLPPPQIKI-SERDTLQNLTGRNISDYLVKTYAQIIGKSLKNKVWVNEFRYGGFSL-----GARSTQVL---PPAEEIDDAIARVRVIFNLEKVTADRFLKSLSAFIN-GLDTKNNVKIWFNNKGWHSIGAFLNVMNNGILRANLPPEKDPSKYGITAFNHPLNLTKEQLSQVALVTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPFLYWLANFIWDMCNYVVPATLVILIFVCFQQKAYVSATNLPVLALLLLLYGWSITPLMYPASFLFEIPSTAYVVLTSVNILIGINGSVSTFVLELFGNN--EIGGINDILKNVLLIFPHFCLGRGLIDMVKNQAM-ADALERFGENRFRSPFEWDMVGKNLFAMAVEGVVFFIITVLIQYRFFFK------PNAKLSPI---GEEDEDVARERQRIVSGAGQGDILELRELTKVY--------------------KRKQKPAVDRLCVGIPPGECFGLLGVNGAGKTTTF 1851

HSP 2 Score: 56.6102 bits (135), Expect = 1.357e-7
Identity = 36/124 (29.03%), Postives = 62/124 (50.00%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G+ +C GS   LK +FGDGY +IL             G       +++FI+S +P + ++ +      + LP + S+    + +F  L +  D L    Y +S T+L++VF+  A D
Sbjct: 2008 RMAIMVNGRFRCLGSVQHLKNRFGDGYTIILRV----------AGPDPDLQPVMKFIESELPGSTLKEKHRNMLQYQLPSSVSS---LAHIFSILAKHKDFLRIEDYSVSQTTLDQVFVNFAKD 2118

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
Match: zgc:172302 (zgc:172302 [Source:ZFIN;Acc:ZDB-GENE-081205-5])

HSP 1 Score: 381.719 bits (979), Expect = 4.579e-113
Identity = 290/888 (32.66%), Postives = 451/888 (50.79%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDL--NQQAFVDKSLISLNFNRNHKL---------LRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCM--NPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDF--------AQSSKLIAQSPTWD----GIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLILL----EVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVK----HEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIISQGKL CCGSS+FLK   G GY L  VK    ++   R   S SG+ L+   + ++  A++  +   +    LP   S     +     LD+       +SYGLSDT+LEE+F++VA++     E        PD           +  EP  D + +  NQQ     SL+         L         L G+ L  QQ+  L  KR  YA R++KG  A+++LP L I + +    +V P+   PA+E+ PW+                  Q  F       N    +P    L S      G  G +C+  +P I  ST ++ F           PN  +   SP+C C+T   +     C +   G PP   + +T  D L NLTG NISDYL+K + ++ +K     +++  N+F        A+ S+ +  S   +     IR     ++  +L+ L  L    + F   +   N  ++W N+KG+ +M ++ NI++N LLR+ +        +GI+  N+P+  ++    Q ++++L+    +V L+I VI A+S + ASFV+FLI+ER+S +K  QFVSG+ P +YW +NF+WD++ Y +P  ++++IFI F  Q+Y+  KN  A +LLL+ YG AI P MYP SF  S PSTA+V L + NL +G   +I+TF+L++     E+L+E+N ILKKVFLIFP F LGRG++D+  N    ++++ +    H  + + WD  G+ LF++    + ++I  I+++     R      +      +     ED DV  ER+R+ + +  DD+L +I+L+K+Y                       ++ AVN LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1003 GDRIAIISQGKLCCCGSSLFLKSHLGTGYYLTAVK----KELQSRTPTSASGNGLVALAQHYVSGARLVEDVGREVVINLPHAASEDGTLALFLAELDKRQAEFGIISYGLSDTTLEEIFLKVAEETGVDAE--------PDEAATPPAVSPSQQGEPPEDRDAVLFNQQV----SLLYTEAQETDPLSGDGRGSVSLTGWGLTWQQLRALFTKRLLYATRSRKGFIAQIVLPALFILIDLLFSLIVPPMGKYPALELQPWMY---------------GEQFTF-----FSNDAPQDPAMQNLLSALLDPPG-FGTKCLFNSPQIPFST-WKLFNS---------PNWTMEHPSPDCMCSTEEVRRMLPDCPEGAGGLPPPQIKRLTG-DILQNLTGRNISDYLMKTYPQILKKSMKTKKWV--NEFRYGGFSLGAKGSQTLIGSLQLEESVMAIRKQYKIAENSSLDQL--LDRLPDLFTDLNSQNNV-KVWYNNKGWHAMVSFVNIMNNGLLRASLPPGPERQKHGITAYNHPLNLTK---EQLSDMVLMTTSVDVLLSISVIFAMSLVPASFVLFLIEERVSKAKHLQFVSGVKPILYWTANFVWDMLNYTVPATLVVLIFIGFQQQAYVSEKNLPALVLLLLLYGWAITPLMYPASFVFSVPSTAYVTLTSINLFIGINGSIATFVLELF--TNEHLREVNRILKKVFLIFPHFCLGRGLIDMAKNQAM-ADALQRLGKCHMPSPIVWDFVGKNLFAMAVEGVVFFIFTILLQYKFFIRCRLPWFE----PVLPPLCAEDEDVGRERDRVKNGRTQDDILTLIDLSKVY--------------------KSGKKPAVNRLCLGIPRGECFGLLGVNGAGKTSTF 1807

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
Match: zgc:172302 (zgc:172302 [Source:ZFIN;Acc:ZDB-GENE-081205-5])

HSP 1 Score: 375.17 bits (962), Expect = 7.591e-111
Identity = 283/898 (31.51%), Postives = 446/898 (49.67%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN--------------FNAQKENFRKGISNSGDK--------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPI--PNGNIPLISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDF--------AQSSKLIAQSPTWD----GIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLILL----EVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSI----VKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            DRIAIISQGKL CCGSS+FLK   G GY L  VK                 A  ++ R   +  G +        L+   + ++  A++  +   +    LP   S     +     LD+       +SYGLSDT+LEE+F++VA++     E        PD           +  EP  D ++ +  +   +  +SL          G+ L  QQ+  L  KR  YA R++KG  A+++LP L I + +    +V P+   PA+E+ PW+                  Q  F       N    +P    L S      G  G +C+       T +   P+   + W     PN  +   SP+C C+T   +     C +   G PP   + +T  D L NLTG NISDYL+K + ++ +K     +++  N+F        A+ S+ +  S   +     IR     ++  +L+ L  L    + F   +   N  ++W N+KG+ +M ++ NI++N LLR+ +        +GI+  N+P+  ++    Q ++++L+    +V L+I VI A+S + ASFV+FLI+ER+S +K  QFVSG+ P +YW +NF+WD++ Y +P  ++++IFI F  Q+Y+  KN  A +LLL+ YG AI P MYP SF  S PSTA+V L + NL +G   +I+TF+L++     E+L+E+N ILKKVFLIFP F LGRG++D+  N    ++++     K     L+WD  G+ LF++    + ++I  I+++     R      +      +     ED DV  ER+R+ + +  DD+L +I+L+K+Y                       ++ AVN LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1056 DRIAIISQGKLCCCGSSLFLKSHLGTGYYLTAVKKELQSRTPTSASGKLLAADTDSTRSDDTGLGSEVNSSVISGLVALAQHYVSGARLVEDVGREVVINLPHAASEDGTLALFLAELDKRQAEFGIISYGLSDTTLEEIFLKVAEETGVDAE--------PDEAATPPAVSPSQQGEPPEDRDETDPLSGDGRGSVSLT---------GWGLTWQQLRALFTKRLLYATRSRKGFIAQIVLPALFILIDLLFSLIVPPMGKYPALELQPWMY---------------GEQFTF-----FSNDAPQDPAMQNLLSALLDPPG-FGTKCLCTGENVGTKFNS-PQIPFSTWKLFNSPNWTMEHPSPDCMCSTEEVRRMLPDCPEGAGGLPPPQIKRLTG-DILQNLTGRNISDYLMKTYPQILKKSMKTKKWV--NEFRYGGFSLGAKGSQTLIGSLQLEESVMAIRKQYKIAENSSLDQL--LDRLPDLFTDLNSQNNV-KVWYNNKGWHAMVSFVNIMNNGLLRASLPPGPERQKHGITAYNHPLNLTK---EQLSDMVLMTTSVDVLLSISVIFAMSLVPASFVLFLIEERVSKAKHLQFVSGVKPILYWTANFVWDMLNYTVPATLVVLIFIGFQQQAYVSEKNLPALVLLLLLYGWAITPLMYPASFVFSVPSTAYVTLTSINLFIGINGSIATFVLELF--TNEHLREVNRILKKVFLIFPHFCLGRGLIDMAKNQAM-ADALQRLGTKQTLEPLEWDFVGKNLFAMAVEGVVFFIFTILLQYKFFIRCRLPWFE----PVLPPLCAEDEDVGRERDRVKNGRTQDDILTLIDLSKVY--------------------KSGKKPAVNRLCLGIPRGECFGLLGVNGAGKTSTF 1878

HSP 2 Score: 55.0694 bits (131), Expect = 4.210e-7
Identity = 42/148 (28.38%), Postives = 69/148 (46.62%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVA----DDPAKINEETKNEKLIPDNLNR 439
            R+AI+  G+ QC GS   LK +FGDGY +IL    +A  ++           +  +IK+      ++        + LP   SNSC  + +F  L    + L    Y +S T+L++VF+  A    DD  +++  T N  L+    +R
Sbjct: 2035 RMAIMVNGRFQCLGSVQHLKNRFGDGYTIIL--RLSAPPKD--------PCPVDAYIKNSFTGIVLKERHHNVLQYQLP---SNSCSLARVFDVLSNNYEELGVTDYSISQTTLDQVFVNFAKEQTDDDDQLSGVTVNGGLVAAQTSR 2169

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
Match: abca1a (ATP-binding cassette sub-family A member 1-like [Source:NCBI gene;Acc:103028164])

HSP 1 Score: 369.777 bits (948), Expect = 5.662e-109
Identity = 290/920 (31.52%), Postives = 465/920 (50.54%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK---------------NFNAQKENFRK-----------GISNSGDK---------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMN---PSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTS-SDKLNNLTGYNISDYLLKNFQR-----LSRKI------FGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQ-----SQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN----ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLK--NSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 +  K + +K           G+ +  +          +   I  H+P A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG++DT+LEE+F++VA+D   ++ ET +  ++     R A  GD ++   PF   D  D N      +S     +  +  +    ++G+ L +QQ + L  KRF YA+R++KG FA+++LP + + + +    +V P    P++E+ P +   +       TF   +   +      LG        + R   E +S  G   IR      P I  +        +    WS     + P  S EC C  +   +   P   G     +I  S +D L NLTG NISDYL+K + +     L  KI      +GG+        A+SS+ +   P  D + D+++      S  +     RFLK    F  +   T N  +IW N+KG+ S+ A+ N+++N +LR+ +    +   + I   N+P+  ++ ++SQ   +   ++V ++I VI A+SF+ ASFV+FLI ER++ +K  QF+SG+ P++YW++NF+WD+  YI+P  ++IIIF+ F  ++Y+ S N     LLL+ YG +I P MYP SFF   PSTA+VVL + N+L+G   ++STF+L++   N   +  INDILK VFLIFP F LGRG++D+  N    ++++ +   N     L WD+ G+ LF++    + ++ + ++I+        C K +  ++ LK I     ED DV  ER+R+       D+L +  LTK+Y                     + ++ AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1101 GDRIAIISHGKLCCVGSSLFLKTQLGTGYYLTLVKRDFDLSLSSCHNSSSTVSYSKNSLKKEDSVSESSSDAGLGSDHESETTTIDVSLISNVIFKHVPSARLAEDLGHELTYVLPYEAAKDGAFVELFHEIDDRLIDLGISSYGIADTTLEEIFLKVAEDNG-VDAETSDGTILSRRNRRHAFGGDHQSCLRPFTEDDSFDFNDSEGDPESRETDWLGGSDGKGSYQVKGWSLKRQQFVALLWKRFLYARRSRKGFFAQIVLPAVFVCIALIFSLIVPPFGKYPSLELEPSMYEEQF------TFVSNDAPEDLQTNKLLGALTERPAYSKRCAEEAKSVDGSCPIRAEEWEMPEIAETVR----DMFVTGNWSM----DHPSPSCECSCEHSKKMLPECPPGAGGLPPPQIKVSQTDTLQNLTGRNISDYLVKTYAQIIGKSLKNKIWVNEFRYGGFSL-----GARSSQPM---PPADEVHDAISHLRRRFSLERGTSADRFLKSLSGFI-QGLDTKNNVKIWFNNKGWHSIGAFLNVMNNGILRTSLPAGLDPAKFAIKAFNHPLNLTKEQLSQVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHLQFISGVQPFLYWLANFVWDMCNYIVPATLVIIIFVCFQQEAYVSSTNLPVLALLLLLYGWSITPLMYPASFFFKIPSTAYVVLTSVNILIGINGSVSTFVLELFGSN--EIGGINDILKNVFLIFPHFCLGRGLIDMVKNQAM-ADALERFGENRFRSPLAWDMVGKNLFAMAVEGVVFFFITVLIQYR-----FCIKARGFSANLKPI---GEEDEDVARERQRILGGGGHSDILELRQLTKVY--------------------KRKQKPAVDRLCVGIPPGECFGLLGVNGAGKTSTF 1965

HSP 2 Score: 56.6102 bits (135), Expect = 1.330e-7
Identity = 36/125 (28.80%), Postives = 64/125 (51.20%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLIL-VKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G  +C GS   LK +FGDGY ++L V   + Q E            +++FI+  +P + ++ +      + LP + S+  +   +F  L +  D L+   Y +S T+L++VF+  A D
Sbjct: 2122 RMAIMVNGTFRCMGSVQHLKNRFGDGYTIVLRVAGADPQLE-----------PVMKFIEHELPGSTLKEKHRNMLQYQLPSSLSSLAR---IFSILAKNKDELHIEDYSVSQTTLDQVFVNFAKD 2232

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Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK---------------NFNAQKENFRK-----------GISNSGDK---------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMN---PSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTS-SDKLNNLTGYNISDYLLKNFQR-----LSRKI------FGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQ-----SQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN----ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLK--NSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 +  K + +K           G+ +  +          +   I  H+P A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG++DT+LEE+F++VA+D   ++ ET +  ++     R A  GD ++   PF   D  D N      +S     +  +  +    ++G+ L +QQ + L  KRF YA+R++KG FA+++LP + + + +    +V P    P++E+ P +   +       TF   +   +      LG        + R   E +S  G   IR      P I  +        +    WS     + P  S EC C  +   +   P   G     +I  S +D L NLTG NISDYL+K + +     L  KI      +GG+        A+SS+ +   P  D + D+++      S  +     RFLK    F  +   T N  +IW N+KG+ S+ A+ N+++N +LR+ +    +   + I   N+P+  ++ ++SQ   +   ++V ++I VI A+SF+ ASFV+FLI ER++ +K  QF+SG+ P++YW++NF+WD+  YI+P  ++IIIF+ F  ++Y+ S N     LLL+ YG +I P MYP SFF   PSTA+VVL + N+L+G   ++STF+L++   N   +  INDILK VFLIFP F LGRG++D+  N    ++++ +   N     L WD+ G+ LF++    + ++ + ++I+        C K +  ++ LK I     ED DV  ER+R+       D+L +  LTK+Y                     + ++ AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1101 GDRIAIISHGKLCCVGSSLFLKTQLGTGYYLTLVKRDFDLSLSSCHNSSSTVSYSKNSLKKEDSVSESSSDAGLGSDHESETTTIDVSLISNVIFKHVPSARLAEDLGHELTYVLPYEAAKDGAFVELFHEIDDRLIDLGISSYGIADTTLEEIFLKVAEDNG-VDAETSDGTILSRRNRRHAFGGDHQSCLRPFTEDDSFDFNDSEGDPESRETDWLGGSDGKGSYQVKGWSLKRQQFVALLWKRFLYARRSRKGFFAQIVLPAVFVCIALIFSLIVPPFGKYPSLELEPSMYEEQF------TFVSNDAPEDLQTNKLLGALTERPAYSKRCAEEAKSVDGSCPIRAEEWEMPEIAETVR----DMFVTGNWSM----DHPSPSCECSCEHSKKMLPECPPGAGGLPPPQIKVSQTDTLQNLTGRNISDYLVKTYAQIIGKSLKNKIWVNEFRYGGFSL-----GARSSQPM---PPADEVHDAISHLRRRFSLERGTSADRFLKSLSGFI-QGLDTKNNVKIWFNNKGWHSIGAFLNVMNNGILRTSLPAGLDPAKFAIKAFNHPLNLTKEQLSQVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHLQFISGVQPFLYWLANFVWDMCNYIVPATLVIIIFVCFQQEAYVSSTNLPVLALLLLLYGWSITPLMYPASFFFKIPSTAYVVLTSVNILIGINGSVSTFVLELFGSN--EIGGINDILKNVFLIFPHFCLGRGLIDMVKNQAM-ADALERFGENRFRSPLAWDMVGKNLFAMAVEGVVFFFITVLIQYR-----FCIKARGFSANLKPI---GEEDEDVARERQRILGGGGHSDILELRQLTKVY--------------------KRKQKPAVDRLCVGIPPGECFGLLGVNGAGKTSTF 1965

HSP 2 Score: 56.6102 bits (135), Expect = 1.330e-7
Identity = 36/125 (28.80%), Postives = 64/125 (51.20%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLIL-VKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G  +C GS   LK +FGDGY ++L V   + Q E            +++FI+  +P + ++ +      + LP + S+  +   +F  L +  D L+   Y +S T+L++VF+  A D
Sbjct: 2122 RMAIMVNGTFRCMGSVQHLKNRFGDGYTIVLRVAGADPQLE-----------PVMKFIEHELPGSTLKEKHRNMLQYQLPSSLSSLAR---IFSILAKNKDELHIEDYSVSQTTLDQVFVNFAKD 2232

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
Match: abca12 (ATP-binding cassette, sub-family A (ABC1), member 12 [Source:ZFIN;Acc:ZDB-GENE-030131-9790])

HSP 1 Score: 186.808 bits (473), Expect = 9.145e-49
Identity = 148/493 (30.02%), Postives = 241/493 (48.88%), Query Frame = 2

Query: 1130 NLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNY-GISVTNYPIADSETKISQFNNLILL---EVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEV--NYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYL-----KRIEIRNTE-DFDVNLERERMSSDQK------SDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            NL+G ++ +YL+    +   K +GG+ F LP+      +++                 P N    +  +             N  ++W N +GY ++PAY N  +NLLL   +   ++  +Y GISV + P A  +  +SQ  ++IL    +  +AI ++L  S ++ SF   ++ ERI+GSKR Q +SG++P  YW  NF +D++ Y +   + I +  AF   +Y  + N  A  LLLI +G A +P MY  S   S    AFV   + N+++G  T ISTF+++ L +  + + L    +I++ +FL+FPQF LG G++ L      +   +++     L  D    +  S F++ I  W  + +  +GIV   +   L +S++     K +E    E D DV  ER R+    +       DD L+++ L K Y +                  N++   AV+ L  GV   +CFGLLGVNGAGKTTTF
Sbjct: 1059 NLSGEDVEEYLMGTTCQYLLKRYGGWSFGLPHSTTSDLEVV-----------------PDNRTLTKVWR-------------NHMKVWYNPEGYHALPAYVNSFNNLLLWDNLPDGEHPGDYKGISVNSKPYAGQQ--LSQ--DMILQNLGDTGVAICILLGFSILTGSFATAVVRERITGSKRLQQISGVSPTFYWAVNFTYDMVSYTVTTGLCIAVIAAFHLPAYTDNSNLGAVSLLLILFGFASLPWMYLISGVFSEEEMAFVTYISINIILGVSTIISTFLVNFLYLSSDSQSLYNAYNIMRWLFLVFPQFCLGWGLVSL------SKQRLMEDIMKLLGSD---PQESSSFAMDITGWPFVALAVNGIVCFTLRLVLTDSFIRWWRRKAVEPGQPELDTDVQAERSRVEEQSRVVDAATPDDTLQLVGLRKRYRLL-----------------NRSF-TAVDGLHLGVSPNQCFGLLGVNGAGKTTTF 1490

HSP 2 Score: 72.0182 bits (175), Expect = 4.477e-13
Identity = 44/141 (31.21%), Postives = 77/141 (54.61%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSG-DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIP 424
            D++AI+  G+ +C G+   LK +FG+G+ + L           R    NS   ++ +FI SH P A ++ + ++Q  F +P   SN+ K S +F+ L++E ++L+   Y +S T+L++VFI  A     + EE+ N    P
Sbjct: 1652 DKLAIMVNGQFKCLGTLQHLKNRFGNGHMIKL-----------RLSSGNSKVTEVTEFITSHFPGAYLKEQHISQLEFQVP---SNAGKLSEIFIALEKEKESLSIQHYSISQTTLDQVFINFARQQIDMEEESSNADARP 1778

HSP 3 Score: 70.0922 bits (170), Expect = 2.064e-12
Identity = 67/269 (24.91%), Postives = 109/269 (40.52%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFN----AQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWS------FVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFI---RVADDPAKINEETKNEKLIPDN----LNRIAVYG-------------------DIENQEPFLDLEDLNQQAFVDK-----------SLISLNFNRNH----KLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAE 655
            SDRIA++  GKL+CCGS  +LK  +G G  L L K       +Q            ++++  ++S +  A +++   +  +      F+LP +  N    S   V L+E ++ L    Y +SDT+LEEV +   RV  +PA +          P +    L +    G                   DI N+ P  +   +N +                 L SL     H    + + G  LL ++   L  KRFH+ +R+ KG  A+
Sbjct:  581 SDRIAVLEHGKLRCCGSPQYLKEIYGQGLTLTLTKKVRVLCLSQSVTLGSRPPFDPERVVSLVRSGVAGAALKSGEDSSGNRNADMVFLLPAHSQNVLGQS-FLVTLEENMEELGLSGYAISDTTLEEVCLRQQRVMSEPA-LGCSASARYFTPTSAASLLTKATQCGPGLYSCSQLVQEAEDQRLKDITNKSPEAESGSINSETAAPPDHTSPAASSILCLSSLWRTEKHLVKKERVTGIHLLVRKTQALIYKRFHHWRRDVKGAAAQ 847

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002495.1 (pep scaffold:Pmarinus_7.0:GL480265:53:27909:1 gene:ENSPMAG00000002218.1 transcript:ENSPMAT00000002495.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 176.407 bits (446), Expect = 1.199e-45
Identity = 150/578 (25.95%), Postives = 265/578 (45.85%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK---------------------NFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAV-----------YGDIENQEPFL-DLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMN-PSIYRSTHYRCFPEYKNNKWSPI-------PNGNIPLISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNF-----------------SRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQ 1549
             DRIAIIS G+L+CCGSS+FLK  FG GY L +VK                      F + + N     +N    + + ++ H+PDA++      + +++LP + +    F+ LF  LDE++  L   SYG+SDT+LEE+F++VA++PA  +  T   KL   N     +           Y   +     L +LE LN+   +D         +  + + G  L+  Q   L IKRFH+A+R++KG  A++ILP + + L +    ++ P    P +++ PW+   +   ++ +     EN    S+ + L NK                     G RCMN  SI  +       E+     SP         N ++   SPEC C+  G ++    C +  +GGPP   R+  ++D L +L+G NISDYL+K + +  RK      ++    +   S          G +   + + P++++ +      +  F+  +K ++                   ++W N+KG+ ++ A+ N+ +N +LRS +    +  +YGI+  N+P+  ++ ++S+
Sbjct:  561 GDRIAIISHGRLRCCGSSLFLKNAFGAGYYLTMVKRSGSGGSNSSCLAGLASSSDEGFGSDESNPDSIAANHVSSVTRLLQQHVPDARLIENFGQELTYLLPSHGAKDGTFALLFKELDEKLAELGVSSYGVSDTTLEEIFLKVAEEPAANSHFTNGVKLSARNSKYTYLQPVHAGCICKNYSTCKKAPAELGELEKLNE---LD--------GKGTQQISGVQLILLQFKALFIKRFHHARRSRKGFVAQIILPAVFVCLALVFSLIIPPFGKYPMLQLQPWMYGEQYTFLSNDA---PENVKTNSLYDALLNKPGF------------------GTRCMNGESIPDAACVETKSEWVQPPMSPAMARTMQSRNWSMEDPSPECRCSGEGRRVILPDCPE-GAGGPPPMQRVQNTTDTLEDLSGRNISDYLVKTYPQAIRKSLKHKYWVNEIRYGGLSV---------GKKKLSHSASPKDMDIV--FTNVKRVFHIENKAVDVLYSGVKDMVSFLGPKETIKVWFNNKGWHAIVAFMNMANNAVLRSSLPAGTDPSDYGITAYNHPLNLTKEQLSE 1094

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006855.1 (pep scaffold:Pmarinus_7.0:GL486953:391:4596:1 gene:ENSPMAG00000006189.1 transcript:ENSPMAT00000006855.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.5362 bits (140), Expect = 1.873e-9
Identity = 26/32 (81.25%), Postives = 28/32 (87.50%), Query Frame = 2

Query: 2459 REVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            R +AV+ LC GVR GECFGLLGVNGAGKTTTF
Sbjct:    1 RILAVDRLCVGVRPGECFGLLGVNGAGKTTTF 32

HSP 2 Score: 48.9062 bits (115), Expect = 2.412e-6
Identity = 33/125 (26.40%), Postives = 59/125 (47.20%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLE---EVFIRVA 373
            R+AI+  G  +C GS   LK +FGDGY + +           R   +    ++L+F     PDA ++    T+  +   Q  S +   + +F  +++ +D L    Y +S T+L+   +VF+  A
Sbjct:  192 RLAIMVNGHFKCLGSIQHLKNRFGDGYMITI-----------RTRSTLHVKEVLRFFSRSFPDAVLKERHHTKVQY---QLKSETLSLAAVFTKMEQVLDVLGVEDYSVSQTTLDNDPQVFVNFA 302

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006988.1 (pep scaffold:Pmarinus_7.0:GL478499:147909:176415:-1 gene:ENSPMAG00000006318.1 transcript:ENSPMAT00000006988.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.8322 bits (120), Expect = 1.178e-6
Identity = 21/36 (58.33%), Postives = 29/36 (80.56%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN 109
            +D  A++SQG+L+C GSS+FLK KFG GYRL L+ +
Sbjct:  649 ADWKAVLSQGRLKCAGSSLFLKTKFGVGYRLTLITD 684

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010397.1 (pep scaffold:Pmarinus_7.0:GL480213:155963:163950:1 gene:ENSPMAG00000009413.1 transcript:ENSPMAT00000010397.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.521 bits (114), Expect = 3.255e-6
Identity = 21/30 (70.00%), Postives = 24/30 (80.00%), Query Frame = 2

Query: 2465 VAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            VAV+ +  G+  GECFGLLG NGAGKTTTF
Sbjct:    4 VAVDGISVGIPAGECFGLLGFNGAGKTTTF 33

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Match: EDO46878 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNL9])

HSP 1 Score: 385.185 bits (988), Expect = 1.831e-115
Identity = 295/891 (33.11%), Postives = 453/891 (50.84%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----NFNAQKENFRKGISNS------------GD---------KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLI-SLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDK--LNNLTGYNISDYLLKNFQRLSRKIF-GGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKL-SQNSWNYGISVTNYPI------ADSETKISQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYN--SNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSD-QKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIISQGKLQCCG+S+FLK  +G+GY L L K       ++   + R  + +             GD          +  FIKSHIP A +     T+ ++VLP + +   KF  +F  LD  +  L+  SYG+SDT+LEEVF++VA++    +EE      +P   +         +  P   L+   Q    + S+  SL F+       G  LL +Q   L +KRFH+ +RN+K   A++ILP + + L + + + + P    PA+E++P            + F ++E   N+ +     N +   PL   L   +    G  G  CM+ +  R       P       SP+P       SP+CDC +    +C     G PP ++   TS D   +  ++G NISDYLLK + +  +K +    + ++  ++   S     +     +R+S + +  + + P                     +IW N+KGY ++PA+ N LSN +LR++ K    +   YGI+  N+P+       D ET + +      ++V +AI V+ ALSF+ ASFV+FL+ ER+S +K    VSG+ PY+YW++N++WD+  Y IP ++ + IF+AF  +SY  + N      LL+ YG +I P MYP S F S  STA++VL + NL VG   T++TFIL++ E + E L +IN +LK VFL+FP + LGRG++DL  N F    S   V    +   WDI G  +F++      ++ + ++IE     ++   K+    LK +E    ED DV  ER+R++S    + D LR++NLTK+Y                     + R VAV+ LC GV +GECFGLLGVNGAGKTTTF
Sbjct:  569 GDRIAIISQGKLQCCGTSLFLKSHYGNGYYLTLTKKTPGLGLDSVDASERDSLGSRSSDSDPISDSVLGDYSDVYCNEKSVTSFIKSHIPSASLVEHVGTELTYVLPSHAAKEGKFQDMFEELDRNLHKLHVGSYGVSDTTLEEVFLKVAEEAQ--SEEAGTSAEVPVRRSTFTF-----SSHPVKCLQPPAQGDSKNDSVDGSLEFDDRES---GLALLLRQFFALLVKRFHHCRRNRKAFIAQIILPAVFVCLAMIVAQ-IRPFYEKPALELTP------------HMFVKEEPYENYVL---YANDDPGEPLARNLSDAFLQYPG-LGTWCMSNNCSRK------PIAFQPSLSPVPTP-----SPDCDC-SEAMNVCPAGAGGPPPPTW---TSYDGNIIQKMSGRNISDYLLKTYMKFVKKRYINKIEIMIVREYGGLSFGDNYNNLPANVRNSSDPAIRRLISPRNV------------------KIWYNNKGYHALPAFLNTLSNTVLRAKAKARGLDPSQYGITAYNHPMNYTKEQLDDETFVKR-----AVDVLVAICVVFALSFVPASFVVFLVSERVSKAKHLHLVSGVKPYIYWLANYVWDMCNYFIPAMLCVFIFLAFGDESYTTAMNFPPTFCLLLLYGWSITPLMYPASHFFSVSSTAYIVLISINLFVGINCTLATFILELFEDDKE-LTDINTVLKSVFLVFPNYCLGRGLIDLAKNQFLGIFSRFGVNLTRDPFSWDITGRNIFAMIIEGFVFFTLTVLIEYRFFIKLRPVKV---VLKPVE---EEDDDVQRERQRVNSGLGHATDALRLMNLTKVYR------------------SRRKRIVAVDRLCVGVPKGECFGLLGVNGAGKTTTF 1369

HSP 2 Score: 55.8398 bits (133), Expect = 7.676e-8
Identity = 38/126 (30.16%), Postives = 61/126 (48.41%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLIL-VKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            +R+AI+  G+++C GS   LK KFGDGY +IL V   N   E           ++ QFI    P+A ++ +      + +P         S LF +L+      +   Y ++ T+L++VFI  A D
Sbjct: 1525 NRVAIMVNGQMKCLGSPQHLKNKFGDGYTVILRVAGSNPDTE-----------QVCQFIIQCFPNAVLKDKHHNMVEYQIP---CQGLSVSRLFGHLEANRKMFDIEDYSVTQTTLDQVFINFAKD 1636

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Match: EDO38879 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBQ0])

HSP 1 Score: 362.459 bits (929), Expect = 3.650e-107
Identity = 288/940 (30.64%), Postives = 448/940 (47.66%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKE----NFRKGISN-------SGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINE-----ETKNEKLI----------PDNLNRI-------------------AVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRN---------HKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESL------PAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSIN-PLTDRLESEYRSDLGESGIRCMNPSIYRST-------------HYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTG-YQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQ-NSWNYGISVTNYPIADSETKISQFNNLILLEVT---LAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNAL----QWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIR------NTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL+C GS ++LKR+FG+GY L LVK   +       +FR+  S+       S +KL  FI SHI  A+++ +T  +++F+LP N      F  LF +L++ ID L   SYG++ T LEEVF++V D    +NE       + +KL           P +L  +                    V    E+ E  L  + L+       +L +   N +            L G  L  QQ   L +KRFHYA+RN KG+ ++++LP L I + + +   + P   L      P+M   P  +   + +  +N   ++  Q   ++++ +G    +  P  D L S  +  L +S +  M     R               H   +  Y N+  +   +       P C C+  G + +C+   +G  P     +T  D L N+TG N+S+YLL   Q      +G   F                        +V Q  P  L+ +      +    ++SK+      W N+KGY ++P Y N+++N +LR+ I  S+ N   YGI+  N+P   + T     +   L + T   +AI+VI+A+SF+ ASFV+FL+ ER + +K  QFVSG++P VYW+SN+LWD+  Y+IP +  I +   F   +Y    N  A + L + YG +I P MYP +F  S  S+A+V +   NL VG   T++TFIL +   + E L ++ND++K + L FP + LGRG+MDL +N + +       E +++    +W I    L  +      ++I+ I+IE               +LKR  I        TED DV  ER+R+      DD++++ NLTKIY                 Y + + + +AV+ LC GV +GECFGLLGVNGAGKT+TF
Sbjct:  801 GDRIAIISSGKLRCVGSPLYLKRRFGEGYNLTLVKKSISSPHGSIGSFRRSTSSNLEASRRSEEKLTSFITSHISSAQLKHKTNQEFTFILPDNSIKRGAFKKLFADLEQNIDVLGIDSYGITHTLLEEVFLKVTD--VSLNETGNMPHHRQDKLPTQLLQFPADKPGHLGHVLLSPPLPTLPTNEGLEMSDVVRNRGEDTERLLGYQPLSDSGTHQGNLYNEASNGHAAGLFEGVGSHTLTGSALQWQQFYALMLKRFHYARRNFKGVISQILLPALFICIAMTMALSLPPKPDLPPLELSPSMFYQPNYIPFGNEAKGMNILAKRLEQ-TLTLSSGIGATCCLRYPQYDLLNSTVK--LTKSQVALMFDKSCRKAIDEVSGVYLKPNKHRFSYIYYTNSSMNVSESVTHQKAGPGCRCSANGTWYLCDQGAAGKQPKELVTITR-DTLQNVTGRNMSEYLLYTTQTFRMHRYGALSF-----------------------GNVVQFVPSRLDSVHIDAVRRLAIREASKS------WYNNKGYHALPTYLNVMNNAILRASIPKSKGNPAAYGITAYNHPFPFNSTSAVHLSADYLRQGTDLVIAIFVIIAMSFVPASFVVFLVTERSTKAKHLQFVSGVDPVVYWLSNYLWDMCNYLIPALACITLLYLFGVPAYASETNFPAVVGLFMLYGWSITPMMYPSAFCFSEASSAYVAMIVLNLFVGVTATVTTFILQLFPDD-EVLTDVNDVIKLISLGFPNYCLGRGLMDLAYNQYLSEYYRQIGEEDSIKSPFEWMIVSRNLVCMLMEGFAFFILTILIEFKF------------FLKRRRIPVSQLPIETEDEDVAAERDRVLRGDADDDLVKIENLTKIY-----------------YSRKRGKHLAVDRLCVGVPQGECFGLLGVNGAGKTSTF 1675

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Match: EDO48951 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI12])

HSP 1 Score: 150.599 bits (379), Expect = 4.014e-37
Identity = 123/410 (30.00%), Postives = 215/410 (52.44%), Query Frame = 2

Query: 1397 NSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIAD-SETKISQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSF-----FISTPSTAFVV-LNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNS------------NSIVKHEYNALQWDIAGEKLFSLFSL--SIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSS---DQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            N+ GY  + +  N LSN+LL    +LS +S   GI  TN+P+ + ++ K     + I + + LAI++ + ++F++ASF+ FL+ ER S +K  QFVSG++ + YW + + WD + Y++P ++I+I+F AF  + +    +  +  LLLI +GL ++P +Y  SF      I+   T FV+ + ++ +L      ++ F+  I  +N   L +  +I+  VF++ P + +   ++D+  NY Y              ++ ++   ++L WD  G    +L+    ++  +I+ ++I+     R+I           I    ++D DV  ER R+ S   +Q   + + V +LTK+Y+            G D          AV++LC G+  GECFGLLGVNGAGKTTTF
Sbjct: 1092 NASGYHIIASSINALSNILLA---ELSGDS-EQGIETTNHPLPNNAQNKADNVTSTISV-LFLAIFMSMGMAFMAASFITFLVQERTSKAKHLQFVSGVDAFSYWSATYTWDFLNYLVPCLLILILFAAFQIEEF--ENDMGSVFLLLILFGLVVLPFIYVMSFAFKSQLIAYAMTVFVLSIMSFGML------LAVFLCRIPSLN---LLDEAEIMHYVFMLLPTYTVSYALIDMSTNYGYRKICSTLQTVESCRDNGIQFTDSSLNWDRPGVGQHALYMAVEAVVLFILTLLIQVRRPYRLI----------PICPWTSQDCDVAGERARVHSLNPEQIKKESVIVKDLTKVYH------------GSD--------RTAVDHLCIGIPRGECFGLLGVNGAGKTTTF 1455

HSP 2 Score: 95.1301 bits (235), Expect = 7.437e-20
Identity = 68/221 (30.77%), Postives = 108/221 (48.87%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNR----NHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAE 655
            DRIAI++ G+L+CCGSS+FLK ++G GY L LVK  +              + ++  ++  +P A++ +    +  FVL  N   S  F  LFV L+   ++    SYG+S T++EEVF++V +          +EK + D LN              L L  L+ Q+ +    I +   R    N+ L  GF L  Q    + +KRF  +KR+KK +  +
Sbjct:  700 DRIAIMADGQLRCCGSSLFLKSRYGVGYHLTLVKKEDCDD-----------NAIINAVRETVPSAQVLSNVGAEIEFVL--NGEASKDFESLFVKLENNKEDYGIASYGVSCTTMEEVFMKVGEG---------SEKTVEDILN--------------LLLRILSSQSLLRYQNIKIKILRLLKSNYPLQTGFALQWQHYKAMLVKRFINSKRDKKSVVTQ 884

HSP 3 Score: 56.9954 bits (136), Expect = 3.800e-8
Identity = 39/124 (31.45%), Postives = 65/124 (52.42%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G+ +C GS+  LK +FG GY L+L      + E     +SN+     QF+ S  P A++        ++   Q +S    +S +F  L+    +LN + Y +S TSLE+VF+ +A +
Sbjct: 1612 RLAIMVNGQFKCVGSAQHLKSRFGMGYTLML------KVEARLVPVSNTE----QFVSSTFPGAQLLESHNGMLTY---QINSTELSWSRIFGELERNRASLNIVDYSVSQTSLEQVFLNLAKE 1722

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Match: EDO32071 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW57])

HSP 1 Score: 55.8398 bits (133), Expect = 2.842e-8
Identity = 37/124 (29.84%), Postives = 63/124 (50.81%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRL--ILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVA 373
            R+ I+ +G+L+C GS+  LK KFG GY L   L  +F +   +      +   +L+ F++   P+AK       +  + +P+  SN  K S  F  L+E   ++    Y  S ++LE+VF+  A
Sbjct:  184 RVGIMVKGQLKCLGSTQHLKSKFGSGYTLEIKLSPSFQSSDPDV-----DMQTQLVAFVEGLFPNAKRTESFGDRVIYKVPK--SNVSKLSSTFATLEEGKRSIGIEEYSFSQSTLEQVFLEFA 300

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Match: EDO28092 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7F9])

HSP 1 Score: 53.5286 bits (127), Expect = 4.649e-8
Identity = 37/117 (31.62%), Postives = 62/117 (52.99%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEV 358
            R+AI+  G+ +C GS+  LK +FG GY L+L      + E     +SN+ ++  QF+ S  P A++        ++   Q +S    +S +F  L+    +LN + Y +S TSLE+V
Sbjct:   76 RLAIMVNGQFKCVGSAQHLKSRFGMGYTLML------KVEARLVPVSNT-EQAQQFVSSTFPGAQLLESHNGMLTY---QINSTELSWSRIFGELERNRASLNIVDYSVSQTSLEQV 182

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Match: ENSORLT00000046301.1 (ATP-binding cassette sub-family A member 1-like [Source:NCBI gene;Acc:101164844])

HSP 1 Score: 399.438 bits (1025), Expect = 1.873e-119
Identity = 297/920 (32.28%), Postives = 462/920 (50.22%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN----FNAQKENFRKGI---------------------------SNSGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINE-ETKNEKLIPD-----------NLNRIAVYGDIENQEPFLD------LEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMN----PSIYRSTHYRCF--PEYKNNKWSPIPNGNIPL--ISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQ--EFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKIS-QFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYN---SNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GK++CCGSS+FLK+ FG GY L LV++      AQ+     GI                           SN  D   + QF++ H+P+A        + +F+LP   +    F+ LF  LD+ +D L   SYG+SDT+LEE+F++VA+D     E     E ++ D           +++R        N +  L       +ED  + A V+         R   ++ G+ L++QQ + L IKRFH+A+R++KG+ A+++LP + + L +    +V      P++E+ PW+   ++      TFY          +N +    +++ + + L      D    G RCM     P +  S+    +  P    +      NGN  +   SP C C+T G  I    C     G P    R+  ++D L NLT  N++D+LLK ++   +K +GG      N    S  L+ +    +            NLEP  +    Q  E   K   T N  ++W  +KG+ SM ++ ++++N +LR  +   QN   YG+SV+N+P+  S+ ++S         +V ++I VI A+SFI ASFV+FLI ER+S +K  QFVSG+NP VYWV++F+WDI  Y+IP  +++ IFI F  ++Y+  +N  A ILLL+ YG AI P MYP SF  + PSTA+VVL   NL +G   +++TF++++ E   E + +IN+I+K+V LIFP F LGRG+MD+  N       SN       + L W++ G+ L ++       +   ++I+     +          L +++    ED DV  ER+R+   + ++DVLR+ +LTK+Y                     +    AV  LC GV   ECFGLLG+NGAGKTTTF
Sbjct:  753 GDRIAIISHGKMRCCGSSIFLKKSFGSGYYLTLVRSGTEVMTAQRSGIISGIAEEKPTESDCPSSSSLDEDRGCQSSDNSNPTDLKHVTQFVRRHVPEAVFLESIGQEITFILPYARARDGTFATLFQELDKVMDKLGLTSYGVSDTTLEEIFLKVAEDTGVDKELSPTKEPVVKDYKKDSRESKRRSMSRFHGKAAKGNTKDELKKKLSNKVEDFKKSASVN--------GRGSVVITGWKLIRQQFLALFIKRFHHARRSRKGLIAQVVLPAIFVCLALVFSLIVPSFTDYPSLELQPWMYNSQT------TFY----------SNDMPEDANVSRVVETL-----VDNPGFGTRCMEGNPIPRLPCSSGASDWFSPSVDQSVADIFLNGNWSMSNPSPSCQCSTPGRTIIMPDCPPGAGGLP-PPQRVQNTTDTLLNLTSINMTDFLLKTYEHSGKKRYGGISVGGIN----SQVLLTEVEIEEAF---------ANLEPPGYGDTIQKAEMVLKKLGTRNNVKVWFYNKGWHSMVSFLSVVNNGILRGYLPEGQNLRQYGLSVSNHPLNLSKEQLSLSAMASTSSDVVVSICVIFAMSFIPASFVLFLIQERVSKAKHLQFVSGVNPTVYWVASFVWDICNYVIPCFLVVGIFICFQQKAYVSPQNLPALILLLVMYGWAITPMMYPASFIFTVPSTAYVVLTCLNLFIGINGSVATFVMELFE--DESITKINNIVKQVLLIFPHFCLGRGLMDMARNQAMANVFSNFGEDRFEDPLSWNMVGKNLIAMSIQGAVMFAFTLLIQYKFFYK------PRLSLPKVQSEEKEDVDVARERQRVHEGRANNDVLRICDLTKVY--------------------PRKSTPAVYRLCVGVPAAECFGLLGINGAGKTTTF 1601

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Match: ENSORLT00000045391.1 (ATP-binding cassette sub-family A member 1-like [Source:NCBI gene;Acc:101164844])

HSP 1 Score: 399.438 bits (1025), Expect = 2.004e-119
Identity = 297/920 (32.28%), Postives = 462/920 (50.22%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN----FNAQKENFRKGI---------------------------SNSGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINE-ETKNEKLIPD-----------NLNRIAVYGDIENQEPFLD------LEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMN----PSIYRSTHYRCF--PEYKNNKWSPIPNGNIPL--ISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQ--EFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKIS-QFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYN---SNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GK++CCGSS+FLK+ FG GY L LV++      AQ+     GI                           SN  D   + QF++ H+P+A        + +F+LP   +    F+ LF  LD+ +D L   SYG+SDT+LEE+F++VA+D     E     E ++ D           +++R        N +  L       +ED  + A V+         R   ++ G+ L++QQ + L IKRFH+A+R++KG+ A+++LP + + L +    +V      P++E+ PW+   ++      TFY          +N +    +++ + + L      D    G RCM     P +  S+    +  P    +      NGN  +   SP C C+T G  I    C     G P    R+  ++D L NLT  N++D+LLK ++   +K +GG      N    S  L+ +    +            NLEP  +    Q  E   K   T N  ++W  +KG+ SM ++ ++++N +LR  +   QN   YG+SV+N+P+  S+ ++S         +V ++I VI A+SFI ASFV+FLI ER+S +K  QFVSG+NP VYWV++F+WDI  Y+IP  +++ IFI F  ++Y+  +N  A ILLL+ YG AI P MYP SF  + PSTA+VVL   NL +G   +++TF++++ E   E + +IN+I+K+V LIFP F LGRG+MD+  N       SN       + L W++ G+ L ++       +   ++I+     +          L +++    ED DV  ER+R+   + ++DVLR+ +LTK+Y                     +    AV  LC GV   ECFGLLG+NGAGKTTTF
Sbjct:  753 GDRIAIISHGKMRCCGSSIFLKKSFGSGYYLTLVRSGTEVMTAQRSGIISGIAEEKPTESDCPSSSSLDEDRGCQSSDNSNPTDLKHVTQFVRRHVPEAVFLESIGQEITFILPYARARDGTFATLFQELDKVMDKLGLTSYGVSDTTLEEIFLKVAEDTGVDKELSPTKEPVVKDYKKDSRESKRRSMSRFHGKAAKGNTKDELKKKLSNKVEDFKKSASVN--------GRGSVVITGWKLIRQQFLALFIKRFHHARRSRKGLIAQVVLPAIFVCLALVFSLIVPSFTDYPSLELQPWMYNSQT------TFY----------SNDMPEDANVSRVVETL-----VDNPGFGTRCMEGNPIPRLPCSSGASDWFSPSVDQSVADIFLNGNWSMSNPSPSCQCSTPGRTIIMPDCPPGAGGLP-PPQRVQNTTDTLLNLTSINMTDFLLKTYEHSGKKRYGGISVGGIN----SQVLLTEVEIEEAF---------ANLEPPGYGDTIQKAEMVLKKLGTRNNVKVWFYNKGWHSMVSFLSVVNNGILRGYLPEGQNLRQYGLSVSNHPLNLSKEQLSLSAMASTSSDVVVSICVIFAMSFIPASFVLFLIQERVSKAKHLQFVSGVNPTVYWVASFVWDICNYVIPCFLVVGIFICFQQKAYVSPQNLPALILLLVMYGWAITPMMYPASFIFTVPSTAYVVLTCLNLFIGINGSVATFVMELFE--DESITKINNIVKQVLLIFPHFCLGRGLMDMARNQAMANVFSNFGEDRFEDPLSWNMVGKNLIAMSIQGAVMFAFTLLIQYKFFYK------PRLSLPKVQSEEKEDVDVARERQRVHEGRANNDVLRICDLTKVY--------------------PRKSTPAVYRLCVGVPAAECFGLLGINGAGKTTTF 1601

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Match: ENSORLT00000025407.2 (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163308])

HSP 1 Score: 385.571 bits (989), Expect = 2.184e-114
Identity = 298/945 (31.53%), Postives = 477/945 (50.48%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQ-KENFRKGISNSG----------------------------DKLL--QFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFL-----DLEDLNQQA----FVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNP-SIYRST--------HYRCFPEYKNNKWSPIPNGNIPL--ISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQR-----LSRKI------FGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQ-----PQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN----ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKN-SYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS++LK + G GY L LVK                 +FN + +EN     S++G                            D  L    I  H+P A++  +   + +++LP + + +  F  LF +LD ++  L   SYG+SDT+LEE+F++VA+D     E   +  L      R   +G  E+Q         D  D N         +   +S    +    + G+ L +QQ + L  KRF YA+R++KG FA+++LP + + + +    +V P    P++E+ PW+                E+Q+ F   +  G+ N    L   +E          G RCM+  SI  S         H    PE     +S   +GN  +   SP C C + G +     C     G PP   + ++++D L NLTG NISDYL+K + +     L+ K+      +GG+        A+S++++   P  + I D++ + +      +     RFL     F N    T N  ++W N+KG+ S+PA+ N+++N +LR+ +    +  NYGI   N+P+  ++ ++SQ   +   ++V ++I VI A+SF+ ASFV+FLI ER++ +K  QF+SG+ P +YW +NFLWD+  Y +P  ++I+IF+ F  ++Y+ S N     LLL+ YG +I P MYP SFF + PSTA+VVL + N+L+G   +ISTF++++   ++E +  INDILK V LIFP F LGRG++D+  N    ++++ +   N     L+WD+ G+ LF++    + ++I+ ++I+        C K +  S L ++     ED DV  ER+R+       D+L +  LTK++                     + ++ AV+ LC G+  GECFGLLGVNGAGKTTTF
Sbjct: 1104 GDRIAIISHGKLCCVGSSLYLKNQLGSGYYLTLVKKDPETSLSSCRNSSSTISFNKKDEENTSVSSSDAGLGSEHESEAATIENGPAASICTVPFVPTDTSLVSALILRHVPTARLVEDLGHELTYILPYSAAKNGAFVELFKDLDLKLHELGISSYGVSDTTLEEIFLKVAEDNGVDTEVLSDGTLPVRARRRTHAFGGGEHQSCLKPISEDDTYDCNDSEGDPDCRETDWLSCTEGKGSYQVNGWSLRRQQFVALMWKRFLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWMY---------------EDQVTFISDDAPGDANMQKLLKSLMEPP------GFGTRCMDGYSIPESPCTMGDEDWHNPDVPESLQQLFS---SGNWTMENPSPSCFCASDGKKRMLPDCPVGAGGLPPPEMK-LSATDTLQNLTGRNISDYLVKTYAQIIGKSLNNKVWVNEFRYGGFSL-----GARSTQVL---PPANEIDDAIERVRNIFELQKGAAADRFLDSLSNFIN-GLDTKNNVKVWFNNKGWHSVPAFMNVMNNAILRANLPPGADPSNYGIMSFNHPLNLTKEQLSQVALVTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPLLYWTANFLWDMCNYFVPAALVILIFVCFQQKAYVSSANLPVLALLLLLYGWSITPLMYPASFFFTIPSTAYVVLTSVNILIGINGSISTFVMELFG-DHE-IGGINDILKNVLLIFPHFCLGRGLIDMVKNQAM-ADALERFGENRFRSPLEWDMVGKNLFAMAVEGVVFFIITLLIQYK-----FCIKPRPISKLTKMGSLGEEDEDVARERQRIVQGLGQGDILELRQLTKVF--------------------KRKQKPAVDRLCVGIPPGECFGLLGVNGAGKTTTF 1986

HSP 2 Score: 51.2174 bits (121), Expect = 5.126e-6
Identity = 34/124 (27.42%), Postives = 60/124 (48.39%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G+ +C GS   LK +FGDGY +IL             G       +++FI+S +  + ++ +      + LP   S+    + +F  L +  D L    Y ++ T+L++VF+  A D
Sbjct: 2143 RMAIMVNGRFRCLGSVQHLKNRFGDGYTIILRV----------AGPDPDLLPVMKFIESELSGSTLKEKHRNMLQYQLP---SSLTSLAHIFSILAKNKDTLRIEDYSVTQTTLDQVFVNFAKD 2253

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Match: abca1a (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163147])

HSP 1 Score: 379.407 bits (973), Expect = 2.521e-112
Identity = 290/921 (31.49%), Postives = 472/921 (51.25%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-NFNAQKENFR------------------------KGISNSGDK---------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-DLN-QQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCM------NPSIYRSTHYRCFPEYKNNKWSPIPNGNIPL--ISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQR-----LSRKI------FGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQ-----PQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN----ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK   G GY L +VK +++   ++ R                         G+ +  D          +   I  H+ +A++  +   + ++VLP   +    F  LF  LD+ + +L   SYG+SDT+LEE+F++VA+D + ++    ++ ++P    R   +GD ++  +PF + E D N  +   +   +     +    ++G+ L +QQ + L  KRF YA+R++KG FA+++LP + + + +    +V P    P++ + P             + Y +  Q +F I+N + +    +P T++L        G  G RCM      N            PE   +       GN      SP C C+  G +     C D   G PP   RI +  D L NLTG N+SDYL+K + +     L  KI      +GG+        A+SS+ ++     D I  ++ Q +      +     RF      F  +   + N  +IW N+KG+ S+ ++ N+++N +LR+ +   ++   +GI+  N+P+  ++ ++SQ   +   ++V ++I VI A+SF+ ASFV+FLI ER++ +K  QF+SG+ P++YW++NF+WD+  YI+P  ++IIIF+ F   +Y+ S N     LLL+ YG +I P MYP SFF   PSTA+VVL + N+L+G   ++STF+L++   N   +  INDILK VFLIFP F LGRG++D+  N    ++++ +   N     L WD+ G+ LF++    + ++ + ++I+       I  +   S+LK I     ED DV  ER+R+ S     D+L +  LTKIY                     + ++ AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1102 GDRIAIISHGKLCCVGSSLFLKTHLGTGYYLTMVKRDYDLALQSCRNSASTVSYSKKTEKEDSISESSSDAGLGSEPDSETTTIDVSLISNVIFKHVREARLVEDLGHELTYVLPYQSAKDGAFVELFHELDDRLTDLGISSYGISDTTLEEIFLKVAED-SGVDAVELSDGVVPTRTRRRHAFGDHQSCLKPFTEDEFDFNDSEESRETDWLGGADGKGSFQVKGWSLKRQQFVALLWKRFLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLALHP-------------SMYGE--QFSF-ISNDMPD----DPHTNKLLGALMEKPG-FGSRCMKGEPIPNTPCTAVEDEWAVPEVSESLRDIFAKGNWTRENPSPLCQCSCEGRKRMLPECPDGAGGLPPPQMRI-SDKDTLQNLTGRNVSDYLVKTYAQIIGKSLKNKIWVNEFRYGGFSL-----GARSSQFLSHK---DDIDVAIAQLRRRFHLERGTAADRFFHSLSSFI-QGLDSKNNVKIWFNNKGWHSISSFLNVMNNGILRASLPAGKDPTKFGITAYNHPLNLTKEQLSQVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPFLYWLANFVWDMCNYIVPATLVIIIFVCFQQDAYVSSTNLPVLALLLLLYGWSITPLMYPASFFFKIPSTAYVVLTSVNILIGINGSVSTFVLELFGSN--EIGGINDILKNVFLIFPHFCLGRGLIDMVKNQAM-ADALERFGENRFRSPLAWDMVGKNLFAMAVEGVVFFCITVLIQYRFC---ITTRSSISHLKPI---GEEDEDVARERQRVLSGSGQSDILELRELTKIY--------------------KRKQKPAVDRLCVGIPPGECFGLLGVNGAGKTSTF 1961

HSP 2 Score: 51.9878 bits (123), Expect = 3.161e-6
Identity = 34/124 (27.42%), Postives = 60/124 (48.39%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G+ +C GS   LK +FGDGY +IL         + R         ++ FI+  +P + ++ +      + LP   S+    + +F  L +  + L    Y +S T+L++VF+  A D
Sbjct: 2118 RMAIMVNGRFRCLGSVQHLKNRFGDGYTIIL--RVAGPDPDLR--------PVMGFIERELPGSTLKEKHRNMLQYQLP---SSLTSLARIFSLLSKNKETLCIEDYSVSQTTLDQVFVNFAKD 2228

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Match: abca1a (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163147])

HSP 1 Score: 378.252 bits (970), Expect = 7.277e-112
Identity = 291/924 (31.49%), Postives = 472/924 (51.08%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-NFNAQKENFR------------------------KGISNSGDK---------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-DLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCM------NPSIYRSTHYRCFPEYKNNKWSPIPNGNIPL--ISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQR-----LSRKI------FGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQ-----PQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLIL-LEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYN----ALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
             DRIAIIS GKL C GSS+FLK   G GY L +VK +++   ++ R                         G+ +  D          +   I  H+ +A++  +   + ++VLP   +    F  LF  LD+ + +L   SYG+SDT+LEE+F++VA+D + ++    ++ ++P    R   +GD ++  +PF + E D N      +S     +     +    ++G+ L +QQ + L  KRF YA+R++KG FA+++LP + + + +    +V P    P++ + P             + Y +  Q +F I+N + +    +P T++L        G  G RCM      N            PE   +       GN      SP C C+  G +     C D   G PP   RI +  D L NLTG N+SDYL+K + +     L  KI      +GG+        A+SS+ ++     D I  ++ Q +      +     RF      F  +   + N  +IW N+KG+ S+ ++ N+++N +LR+ +   ++   +GI+  N+P+  ++ ++SQ   +   ++V ++I VI A+SF+ ASFV+FLI ER++ +K  QF+SG+ P++YW++NF+WD+  YI+P  ++IIIF+ F   +Y+ S N     LLL+ YG +I P MYP SFF   PSTA+VVL + N+L+G   ++STF+L++   N   +  INDILK VFLIFP F LGRG++D+  N    ++++ +   N     L WD+ G+ LF++    + ++ + ++I+       I  +   S+LK I     ED DV  ER+R+ S     D+L +  LTKIY                     + ++ AV+ LC G+  GECFGLLGVNGAGKT+TF
Sbjct: 1102 GDRIAIISHGKLCCVGSSLFLKTHLGTGYYLTMVKRDYDLALQSCRNSASTVSYSKKTEKEDSISESSSDAGLGSEPDSETTTIDVSLISNVIFKHVREARLVEDLGHELTYVLPYQSAKDGAFVELFHELDDRLTDLGISSYGISDTTLEEIFLKVAED-SGVDAVELSDGVVPTRTRRRHAFGDHQSCLKPFTEDEFDFNDSEGDPESRETDWLGGADGKGSFQVKGWSLKRQQFVALLWKRFLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLALHP-------------SMYGE--QFSF-ISNDMPD----DPHTNKLLGALMEKPG-FGSRCMKGEPIPNTPCTAVEDEWAVPEVSESLRDIFAKGNWTRENPSPLCQCSCEGRKRMLPECPDGAGGLPPPQMRI-SDKDTLQNLTGRNVSDYLVKTYAQIIGKSLKNKIWVNEFRYGGFSL-----GARSSQFLSHK---DDIDVAIAQLRRRFHLERGTAADRFFHSLSSFI-QGLDSKNNVKIWFNNKGWHSISSFLNVMNNGILRASLPAGKDPTKFGITAYNHPLNLTKEQLSQVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPFLYWLANFVWDMCNYIVPATLVIIIFVCFQQDAYVSSTNLPVLALLLLLYGWSITPLMYPASFFFKIPSTAYVVLTSVNILIGINGSVSTFVLELFGSN--EIGGINDILKNVFLIFPHFCLGRGLIDMVKNQAM-ADALERFGENRFRSPLAWDMVGKNLFAMAVEGVVFFCITVLIQYRFC---ITTRSSISHLKPI---GEEDEDVARERQRVLSGSGQSDILELRELTKIY--------------------KRKQKPAVDRLCVGIPPGECFGLLGVNGAGKTSTF 1964

HSP 2 Score: 51.9878 bits (123), Expect = 3.135e-6
Identity = 34/124 (27.42%), Postives = 60/124 (48.39%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G+ +C GS   LK +FGDGY +IL         + R         ++ FI+  +P + ++ +      + LP   S+    + +F  L +  + L    Y +S T+L++VF+  A D
Sbjct: 2121 RMAIMVNGRFRCLGSVQHLKNRFGDGYTIIL--RVAGPDPDLR--------PVMGFIERELPGSTLKEKHRNMLQYQLP---SSLTSLARIFSLLSKNKETLCIEDYSVSQTTLDQVFVNFAKD 2231

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Match: SMESG000029534.1 (SMESG000029534.1)

HSP 1 Score: 1509.97 bits (3908), Expect = 0.000e+0
Identity = 776/857 (90.55%), Postives = 805/857 (93.93%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQP----QNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSW-NYGISVTNYPI-ADSETKISQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAELILPILMITLMIALLKLVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNF++LSRK++GG+QF+LP+ F  SSKLI  SP W+ +RD VN SQ      NL  L+F+ Y Q+ F       +F+RIW+NSKGY SMPAYANI SNLLLRSR+  S   + +YGISV+N+PI  +  TK       ++LE++LAI+VI  LSFI ASFVIFL++ER+SGSKRQQFVSGINPYVYWVSNFLWDIMKYIIPIIIIIIIFIAFDYQSYI SKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLN YNLLVGTITTISTFILDILE NYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF
Sbjct:  947 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAELILPILMITLMIALLKLVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFRKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWVNSKGYVSMPAYANIFSNLLLRSRLNKSAVKFIDYGISVSNFPIEMEQSTKFLDLVIQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYIIPIIIIIIIFIAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNVYNLLVGTITTISTFILDILEGNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 1803

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Match: SMESG000029537.1 (SMESG000029537.1)

HSP 1 Score: 1070.46 bits (2767), Expect = 0.000e+0
Identity = 593/854 (69.44%), Postives = 685/854 (80.21%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPA-KINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLE-DLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXX-XXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            SDR+AIISQGKLQCCGS VFLKRKFG+GY L L+KN N    + R     +G+ +L+F+K +I DA+M  E+  QW+ VLPQND NS KF+ LF NLD+ +  ++ +SYGLSDTSLEEVF++VADDP  K+  + K+      N+ ++ +  +    E FL+   D  Q  F+D+S           LL+GFPLL+QQII L IKR+HYAKR+ KG  AELIL  ++++ +++ L   + P + +P M+ISPWLMM K    NLNTFYRKEN         LG       L ++LESEYRSDLGESGIRCMNPSIYR  +Y+CF   +NN WSP    +IP++SPECDC+ TG QICND RSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYIIPIIIIIIIFIAFDYQSYI SKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVG+ITT+STFILDI+E   E  +  N+ILKKVFLIFPQ++LGRG++DL  NY   + +    +Y+A  W++A EKL SL  L + WWI+LIIIE G++NR++   LK SY    +I+ TEDFD++LE+ RM+S+QK DDVL+VINLTKIYN    F+  C  K K+N ++N+ ++ AVNNLCFGVREGECFGLLGVNGAGKTTTF
Sbjct:  899 SDRVAIISQGKLQCCGSLVFLKRKFGEGYYLSLLKNQNNHSNSNR-----NGENILKFVKIYIADARMMEESRLQWTIVLPQNDINSRKFTELFKNLDQHMAEMSIISYGLSDTSLEEVFLKVADDPMNKLINKEKSYYSYYCNILKMKLRINATKTEIFLNQNPDQKQSKFLDQS---------DHLLKGFPLLQQQIIALHIKRYHYAKRDFKGFLAELILPVLMILFIILFLKISILPKKQIP-MQISPWLMMSKMGKENLNTFYRKENI-------SLG-------LINKLESEYRSDLGESGIRCMNPSIYRLDNYQCFYRNENNMWSPASILDIPMVSPECDCSKTGNQICNDLRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKISQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYIIPIIIIIIIFIAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKYDAFDWEVASEKLASLILLFLLWWIILIIIERGVINRVLYRMLKVSYFNN-KIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCC-KNKNNDVENENQKFAVNNLCFGVREGECFGLLGVNGAGKTTTF 1721

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Match: SMESG000032891.1 (SMESG000032891.1)

HSP 1 Score: 933.71 bits (2412), Expect = 0.000e+0
Identity = 511/855 (59.77%), Postives = 631/855 (73.80%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQ-QAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNL-EPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKI-SQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNT-EDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            SDRIAIISQGKLQCCGSSVFLK++FGDGY LILVKN  +Q+E+FR GIS+SG+K+L FI++HI DAKM  ET TQW+ VL QN+ N+ KFS LF ++D  +  LN +SYGLSDTSLEEVF++VADDPA   EE K++++  ++L+ +   G+       L   D  +   F D + I         LL G  LL QQ++GLQ+KRFHY KRN KG  AEL+LPIL+I +MIA  K+ + L   P MEISPWLMMPK+RS+NLNTFYRKEN              S N L D+L   YRSDL E+G RCMN S+YR   Y C      N+W+  P   IPL++  CDC  TGYQ+C++  SGGP NSYR+M S+DKLNNLTGYNISD+L+K F+   +K +GGYQFLLP+ F QS KLI   P WD IR   N S   +  + L FL YFQEFFN S    NF+RIWINSKGYAS+PAY NI SNLLLR+R +   N  NYGISV NYP+  +++ + S+ N  + +EV+LA++VI  LSFI ASFVIFLI+ERI+GSKRQQ VSG+NPYVYW+SNFLWDI+KYI+PI II++IF+AFDYQSYI SKN  AFI LLIFYGLAIIPHMYPFSF +STPSTAFVVL+AYNLLVG+ITTISTF LD+L+ + E LK +ND+LKKVFL+FPQ+ LGRG+MDL FNY   + S  K +Y+   W   GEKL SL  L +GWWIV++IIESGI+NR +CGK+KN  LK  EI++  ED DV +ERER+ S++ SDDVL+VI LTK+YN  L  K+ C +K   + ++N+ R++AVNNLCFGVREGECFGLLGVNGAGKTTTF
Sbjct:  873 SDRIAIISQGKLQCCGSSVFLKKEFGDGYYLILVKNSRSQEEDFRSGISSSGEKVLNFIRAHITDAKMIEETRTQWTIVLSQNEINNGKFSDLFADIDRSLSGLNIVSYGLSDTSLEEVFLKVADDPAGTVEEIKDKQITTEDLDSLTDDGNFPRPSSRLSFRDKREFPRFDDLNSIPYESGAPSSLLTGSALLCQQLLGLQVKRFHYTKRNIKGFVAELVLPILLIVIMIAFSKISSNLNYQPPMEISPWLMMPKARSLNLNTFYRKEN--------------SSNTLIDKLVEGYRSDLSEAGTRCMNQSVYRLDSYPC-SSRTGNQWTGNPPEPIPLLTAACDCKKTGYQMCSNSSSGGPQNSYRLMASTDKLNNLTGYNISDHLIKKFKSYIKKQYGGYQFLLPSPFGQSCKLIGSLPIWDAIRSQSNSSNSSSNSDQLPFLNYFQEFFNLSGIKTNFTRIWINSKGYASLPAYGNIFSNLLLRTRFE--SNGSNYGISVANYPLKYTQSDLLSKLNTQMFIEVSLAVFVIFGLSFIPASFVIFLIEERITGSKRQQIVSGVNPYVYWMSNFLWDILKYIVPIFIIVLIFVAFDYQSYIGSKNLGAFITLLIFYGLAIIPHMYPFSFLLSTPSTAFVVLDAYNLLVGSITTISTFFLDLLQKDDETLKPVNDVLKKVFLLFPQYGLGRGMMDLSFNYLTFNISNGKQDYDPFGWSTTGEKLCSLSVLFVGWWIVVLIIESGIINRTLCGKIKNRNLKAKEIKDEFEDVDVAVERERIISEKISDDVLKVIKLTKVYNQSLNVKNTCCKKVVKDALENEKRKLAVNNLCFGVREGECFGLLGVNGAGKTTTF 1710

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Match: SMESG000032861.1 (SMESG000032861.1)

HSP 1 Score: 930.243 bits (2403), Expect = 0.000e+0
Identity = 507/855 (59.30%), Postives = 634/855 (74.15%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQ-QAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNL-EPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKI-SQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNT-EDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            SDRIAIISQGKLQCCGSSVFLK++FGDGY LILVKN  +Q+E+FR GIS+SG+K+L FI++HI DAKM  ET TQW+ VLPQN+ NS KFS LF ++D  +  LN +SYGLSDTSLEEVF++VADDPA   EE K++++  ++L+ +   G+       L      +   F D + I         LL G  LL+QQ++GLQ+KRFHY KRN KG  AEL+LPIL+I +MIA  K+ + L   P MEISPWLMMPK+RS+NLNTFYRKEN              S N L D+L   YRSDL E+G RCMN S+YR   Y C      N+W+  P   IPL++  CDCNTTG+Q+C++  SGGP NSYR+M S+DKLNNLTGYNISD+L+K F+   +K +GG+QFLLP+ F QS KLI   P WD +R   N S   +  + L FL YFQEFFN S    NF+RIWINSKGYAS+PAY NI SNLL+R+R +   N  NYGISV NYP+  +++ + S+ N  + +EV+LA++VI  LSFI ASFVIFLI+ERI+GSKRQQ VSG+NPYVYW+SNFLWDI+KYI+PI II++IF+AFDYQSYI SKN  AFI LLIFYGLAIIPHMYPFSF +STPSTAFVVL+AYNLL+G+ITTISTF LD+L+ + E LK +ND+LKKVFL+FPQ+ LGRG+MDL FNY   + S  K +Y+   W   GEKL SL  L +GWWIV+ IIESGI+NR++CGK+KN  LK  E+++  ED DV +ERER+ S++ SDDVL+VI LTK+YN  L  K+ C +K   + ++N+ R++AVNNLCFGV+EGECFGLLGVNGAGKTTTF
Sbjct:  883 SDRIAIISQGKLQCCGSSVFLKKEFGDGYYLILVKNSRSQEEDFRSGISSSGEKVLNFIRAHITDAKMIEETRTQWTIVLPQNEINSGKFSDLFADIDRSLSGLNIVSYGLSDTSLEEVFLKVADDPAGTVEEIKDKQITAEDLDSLTDDGNFPRPSSRLSFRCKREFPRFDDLNSIPYESGAPSSLLTGSALLRQQLLGLQVKRFHYTKRNIKGFVAELVLPILLIVVMIAFSKISSNLNYQPPMEISPWLMMPKARSLNLNTFYRKEN--------------SSNTLIDKLVEGYRSDLSEAGTRCMNQSVYRLDSYPCSSSI-GNQWTGNPPEPIPLLTAACDCNTTGFQLCSNSSSGGPQNSYRLMASTDKLNNLTGYNISDHLIKKFKSYIKKQYGGFQFLLPSPFGQSCKLIGSLPIWDAMRSQSNSSNSSSNSDQLPFLNYFQEFFNLSGIKTNFTRIWINSKGYASLPAYGNIFSNLLMRTRFE--SNGSNYGISVANYPLKYTQSDLLSKLNTQMFVEVSLAVFVIFGLSFIPASFVIFLIEERITGSKRQQIVSGVNPYVYWMSNFLWDILKYIVPIFIIVLIFVAFDYQSYIGSKNLGAFITLLIFYGLAIIPHMYPFSFLLSTPSTAFVVLDAYNLLLGSITTISTFFLDLLQQDDETLKPVNDVLKKVFLLFPQYGLGRGMMDLSFNYLTFNISNGKQDYDPFGWSTTGEKLCSLSVLFVGWWIVVFIIESGIINRMLCGKIKNRNLKAKEMKDEFEDVDVAVERERIISEKISDDVLKVIKLTKVYNQSLNVKNTCCKKVVKDTLENEKRKLAVNNLCFGVQEGECFGLLGVNGAGKTTTF 1720

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Match: SMESG000068605.1 (SMESG000068605.1)

HSP 1 Score: 918.302 bits (2372), Expect = 0.000e+0
Identity = 481/853 (56.39%), Postives = 624/853 (73.15%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDK-SLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGISVTNYPIADSETKI-SQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYICSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTITTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTTF 2554
            SDRIAIISQGKLQCCGSSVFLK++FG+GY LI+VK  + Q E+F+  +S SG   L+FI++H+PDAKM  ET +QW+  LPQ+++N  KF  LF NLD  +++L  ++YGLSDTSLEEVF++VADDP+      K +KL P+ L+ +   G+       L L D ++ A +++   +S      + +L G  L  QQIIGLQIKRFHY +RN K   AEL+LP+LMI ++I LL + +PL   P M ISPWLMMPK+R +NLNTFYRKE+                N + D +E+ YRSD+GESG+RCMN ++YR  +Y C+PE   N+WS IP+  I L SPECDC+ TG+Q C+DP SGGP  S RIMTSSD+L N+TGYNISDYLLK F+   +K +GGYQFLLP++F  SS  I  SP WDGI   +N S   +   L FL Y Q FFN+S    N++RIW+NSKG+ SMPAY NI SN+LLRS++    +   YGISVTNYP+  S+T + SQ N  + LEV+LAI+VI  LSFI ASFVIFLI+ERISG+KRQQFVSG+NPY+YW+SNF+WD++KYIIP+ I+++IF+ F+YQSYI ++NA AFI+LL+FYGLAIIPHMYPFSF +S PSTAFV+L+AYNLLVG ITTI+TF LD+L+V+   LK  ND+LKK+FLIFPQ++LGRG+MDL FNY   + S  K  Y+   W+  G+KL SL  L I WW V+  IESGI+NR ICG++KN  LK  E+++ ED DV LERERM+  +++ DVL+VINLTKIYN  L   + C ++   + + ++ R++AVNN+CFGV+EGECFGLLGVNGAGKTTTF
Sbjct:  909 SDRIAIISQGKLQCCGSSVFLKKEFGNGYYLIIVKTESIQWEDFQNELSISGGIALKFIQNHVPDAKMMEETRSQWTIALPQSENNCSKFPDLFDNLDRAMEDLGIVTYGLSDTSLEEVFLKVADDPSGEVGGIKEKKLTPEKLDALTDGGNFPRPASILSLRDKSEFAKIEEIRRVSFKSEITYSMLTGISLFIQQIIGLQIKRFHYTRRNMKSFIAELVLPVLMILMIIGLLNISSPLSDAPPMVISPWLMMPKTRLVNLNTFYRKES--------------PSNAIIDSMENVYRSDVGESGVRCMNSAVYRLGNYSCYPENNVNQWSAIPSAPISLSSPECDCSKTGFQFCSDPLSGGPTISSRIMTSSDQLGNITGYNISDYLLKKFKTFIKKQYGGYQFLLPSNFGLSSNSIGSSPIWDGISSYINSSPNNSNS-LGFLNYSQRFFNQSGIKTNYTRIWVNSKGFVSMPAYENIFSNILLRSKLNSFSDISKYGISVTNYPLKFSQTDLQSQLNTQMFLEVSLAIFVIFGLSFIPASFVIFLIEERISGAKRQQFVSGVNPYLYWISNFMWDLVKYIIPVAIVLVIFVLFNYQSYIGTQNAGAFIVLLLFYGLAIIPHMYPFSFVLSNPSTAFVILDAYNLLVGAITTIATFFLDLLQVDDPSLKPANDVLKKIFLIFPQYDLGRGMMDLSFNYLQYNISGGKVTYDPFGWETTGQKLCSLIILFIAWWSVIFTIESGIINRSICGRIKNYKLKERELQHEEDTDVFLERERMTKRKENVDVLKVINLTKIYNPSLNINNKCCKRAVADSLSSEKRKLAVNNICFGVKEGECFGLLGVNGAGKTTTF 1746

HSP 2 Score: 50.8322 bits (120), Expect = 5.964e-6
Identity = 41/133 (30.83%), Postives = 61/133 (45.86%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDA---KMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINE 397
            R++I+  G+++C G+   LK KFGD Y + +  NF          I N  DK+   +K+  P     K E     Q+ F      + S K S +F   +    N     Y +S TSL+EVFI  A + +  NE
Sbjct: 1904 RLSIMVNGEMKCLGNVQHLKSKFGDDYFVKIRMNF----------IENESDKIKAIMKTQFPQGVSLKDENFITLQYRF------NCSLKLSTIFHFFENLKANGVIADYSVSQTSLDEVFINFAKNKSSNNE 2020

The following BLAST results are available for this feature:

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Yeast
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ABCA1	1.296e-110	31.43	ATP binding cassette subfamily A member 1 [Source:...	[more]
ABCA7	6.552e-100	29.95	ATP binding cassette subfamily A member 7 [Source:...	[more]
ABCA4	1.497e-96	29.27	ATP binding cassette subfamily A member 4 [Source:...	[more]
ABCA4	5.291e-88	28.67	ATP binding cassette subfamily A member 4 [Source:...	[more]
ABCA2	2.465e-77	32.35	ATP binding cassette subfamily A member 2 [Source:...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
abt-2	1.912e-34	27.70	ABC Transporter family [Source:UniProtKB/TrEMBL;A...	[more]
abt-2	2.089e-34	27.70	ABC Transporter family [Source:UniProtKB/TrEMBL;A...	[more]
ced-7	8.405e-27	26.47	ABC transporter ced-7 [Source:UniProtKB/Swiss-Pro...	[more]
ced-7	1.088e-26	26.47	ABC transporter ced-7 [Source:UniProtKB/Swiss-Pro...	[more]
ced-7	1.231e-26	26.47	ABC transporter ced-7 [Source:UniProtKB/Swiss-Pro...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG34120	4.769e-28	26.12	gene:FBgn0083956 transcript:FBtr0110827	[more]
CG34120	5.065e-28	26.12	gene:FBgn0083956 transcript:FBtr0343018	[more]
CG34120	6.588e-28	26.12	gene:FBgn0083956 transcript:FBtr0299591	[more]
ABCA	4.090e-25	27.78	gene:FBgn0031170 transcript:FBtr0306679	[more]
ABCA	4.707e-25	27.78	gene:FBgn0031170 transcript:FBtr0332489	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
abca1b	7.871e-115	31.47	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
abca1b	2.190e-113	31.10	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
abca1a	2.318e-106	31.14	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
abca1a	2.318e-106	31.14	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
abca4b	2.864e-106	29.96	ATP-binding cassette, sub-family A (ABC1), member ...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ABCA1	2.672e-117	31.95	ATP binding cassette subfamily A member 1 [Source:...	[more]
ABCA1	3.387e-114	31.47	ATP binding cassette subfamily A member 1 [Source:...	[more]
ABCA1	2.916e-113	31.42	ATP binding cassette subfamily A member 1 [Source:...	[more]
ABCA1	2.105e-112	31.00	ATP binding cassette subfamily A member 1 [Source:...	[more]
ABCA1	3.651e-111	30.81	ATP binding cassette subfamily A member 1 [Source:...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Abca1	2.302e-113	31.82	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
Abca4	7.879e-103	29.25	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
Abca7	1.265e-94	29.84	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
Abca7	1.265e-94	29.84	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
Abca4	1.794e-94	28.54	ATP-binding cassette, sub-family A (ABC1), member ...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P41233\|ABCA1_MOUSE	1.610e-112	31.82	Phospholipid-transporting ATPase ABCA1 OS=Mus musc...	[more]
sp\|O95477\|ABCA1_HUMAN	6.226e-110	31.43	Phospholipid-transporting ATPase ABCA1 OS=Homo sap...	[more]
sp\|O35600\|ABCA4_MOUSE	5.511e-102	29.25	Retinal-specific phospholipid-transporting ATPase ...	[more]
sp\|Q8IZY2\|ABCA7_HUMAN	3.146e-99	29.95	Phospholipid-transporting ATPase ABCA7 OS=Homo sap...	[more]
sp\|P78363\|ABCA4_HUMAN	7.189e-96	29.27	Retinal-specific phospholipid-transporting ATPase ...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3JVH4	4.999e-147	34.25	LOW QUALITY PROTEIN: ATP-binding cassette sub-fami...	[more]
V4ABB8	2.403e-134	35.11	Uncharacterized protein OS=Lottia gigantea OX=2251...	[more]
N1PB02	4.893e-131	34.52	Uncharacterized protein OS=Capitella teleta OX=283...	[more]
A0A2T7NPT0	1.319e-120	34.75	Uncharacterized protein OS=Pomacea canaliculata OX...	[more]
A0A1D1VFB8	8.082e-119	35.51	Uncharacterized protein OS=Ramazzottius varieornat...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000016919.2	3.109e-114	31.18	pep primary_assembly:Astyanax_mexicanus-2.0:8:9912...	[more]
zgc:172302	4.579e-113	32.66	zgc:172302 [Source:ZFIN;Acc:ZDB-GENE-081205-5]	[more]
zgc:172302	7.591e-111	31.51	zgc:172302 [Source:ZFIN;Acc:ZDB-GENE-081205-5]	[more]
abca1a	5.662e-109	31.52	ATP-binding cassette sub-family A member 1-like [S...	[more]
abca1a	5.662e-109	31.52	ATP-binding cassette sub-family A member 1-like [S...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
abca12	9.145e-49	30.02	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
ENSPMAT00000002495.1	1.199e-45	25.95	pep scaffold:Pmarinus_7.0:GL480265:53:27909:1 gene...	[more]
ENSPMAT00000006855.1	1.873e-9	81.25	pep scaffold:Pmarinus_7.0:GL486953:391:4596:1 gene...	[more]
ENSPMAT00000006988.1	1.178e-6	58.33	pep scaffold:Pmarinus_7.0:GL478499:147909:176415:-...	[more]
ENSPMAT00000010397.1	3.255e-6	70.00	pep scaffold:Pmarinus_7.0:GL480213:155963:163950:1...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46878	1.831e-115	33.11	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38879	3.650e-107	30.64	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48951	4.014e-37	30.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32071	2.842e-8	29.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28092	4.649e-8	31.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000046301.1	1.873e-119	32.28	ATP-binding cassette sub-family A member 1-like [S...	[more]
ENSORLT00000045391.1	2.004e-119	32.28	ATP-binding cassette sub-family A member 1-like [S...	[more]
ENSORLT00000025407.2	2.184e-114	31.53	ATP-binding cassette sub-family A member 1 [Source...	[more]
abca1a	2.521e-112	31.49	ATP-binding cassette sub-family A member 1 [Source...	[more]
abca1a	7.277e-112	31.49	ATP-binding cassette sub-family A member 1 [Source...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000029534.1	0.000e+0	90.55	SMESG000029534.1	[more]
SMESG000029537.1	0.000e+0	69.44	SMESG000029537.1	[more]
SMESG000032891.1	0.000e+0	59.77	SMESG000032891.1	[more]
SMESG000032861.1	0.000e+0	59.30	SMESG000032861.1	[more]
SMESG000068605.1	5.964e-6	56.39	SMESG000068605.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30007539 ID=SMED30007539|Name=ATP-binding cassette sub-family A member 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2554bp
CAGTGACAGAATTGCTATCATTTCCCAGGGAAAACTCCAATGTTGCGGCT
CATCAGTGTTTTTGAAACGGAAATTCGGCGATGGATATCGATTGATCCTG
GTAAAGAATTTCAACGCTCAAAAAGAAAATTTCCGCAAAGGAATTTCTAA
TTCCGGAGATAAGTTATTGCAATTTATCAAGTCCCATATTCCGGATGCGA
AGATGGAAACCGAAACAATGACTCAATGGAGCTTTGTTTTACCGCAAAAT
GATAGCAATAGTTGCAAATTCTCTGGGCTATTTGTGAATCTCGATGAAGA
AATTGACAACTTGAATGCGTTGTCATATGGATTGTCGGACACATCTCTTG
AGGAAGTGTTTATTAGGGTAGCTGATGATCCAGCAAAAATAAACGAGGAA
ACAAAGAATGAAAAACTGATTCCAGATAACTTGAATAGAATTGCTGTCTA
TGGTGACATAGAAAACCAGGAACCCTTTCTAGACCTCGAGGACCTCAATC
AGCAGGCGTTTGTTGATAAATCCTTGATTTCATTGAATTTTAATAGAAAT
CATAAATTATTAAGAGGATTTCCCCTATTAAAACAGCAAATAATTGGACT
GCAAATTAAAAGATTCCATTACGCAAAACGAAACAAAAAAGGGATTTTCG
CTGAATTGATATTACCGATTTTAATGATTACACTAATGATTGCTTTATTG
AAACTCGTAAATCCCCTGGAAAGCTTACCGGCAATGGAAATCAGTCCCTG
GTTGATGATGCCAAAATCTAGATCAATAAATTTAAATACATTTTATCGGA
AAGAAAATCAATTAAATTTTTCGATAACAAATCAATTGGGAAATAAAAAT
TCAATAAATCCTTTGACGGATCGATTGGAAAGCGAATATCGATCCGATCT
CGGTGAATCGGGAATCAGGTGCATGAATCCATCAATTTATCGATCAACCC
ATTATCGGTGTTTCCCTGAATATAAAAACAATAAATGGTCACCTATTCCT
AATGGAAACATTCCATTAATTAGCCCAGAATGTGATTGCAATACAACCGG
ATATCAGATCTGCAATGATCCTCGCAGCGGTGGTCCACCGAATTCATACC
GAATAATGACCAGTAGTGATAAACTGAACAATTTAACCGGATATAATATA
TCGGATTATTTATTGAAAAATTTTCAAAGGTTATCGAGAAAAATTTTTGG
AGGTTACCAATTTTTATTGCCAAATGATTTTGCACAGTCATCGAAATTAA
TTGCTCAGTCCCCAACATGGGATGGAATACGTGATTCCGTAAATCAATCT
CAACCACAAAACCTGGAGCCATTAAGGTTTTTAAAATACTTTCAAGAGTT
TTTCAATAAGTCTAGCAAGACGATGAATTTTTCACGAATCTGGATAAATT
CTAAAGGATACGCATCAATGCCAGCGTACGCAAATATTCTGAGCAATTTG
TTGTTGCGATCTAGAATAAAATTATCACAAAATTCTTGGAACTATGGGAT
TTCCGTTACAAATTACCCAATTGCAGATAGTGAAACAAAGATTTCTCAGT
TTAATAATTTAATATTATTAGAAGTTACTTTGGCAATTTACGTAATATTG
GCGCTGTCATTTATATCAGCCAGTTTTGTTATTTTTCTAATAGACGAACG
AATTAGTGGCTCCAAGCGGCAGCAATTCGTGTCGGGAATCAACCCCTACG
TGTATTGGGTATCCAATTTCTTGTGGGACATCATGAAATACATCATTCCC
ATTATTATCATCATAATAATTTTTATTGCCTTTGATTATCAATCATATAT
CTGCAGCAAAAATGCTCTTGCTTTCATTCTTCTTTTAATTTTCTACGGAT
TAGCTATTATTCCCCATATGTATCCATTTAGCTTCTTCATTTCCACACCA
AGCACCGCATTTGTGGTGTTAAATGCCTACAATTTATTAGTCGGCACAAT
TACAACGATTTCCACATTTATTTTAGATATTTTGGAAGTCAATTATGAAT
ATTTAAAAGAGATTAATGACATTTTGAAAAAGGTTTTCTTAATATTCCCC
CAGTTCAATCTCGGTAGAGGGATCATGGATTTATTTTTTAATTACTTTTA
CAATAGTAATTCGATAGTTAAACATGAATATAACGCTTTACAGTGGGATA
TTGCCGGGGAGAAACTTTTTTCACTTTTCAGTTTGTCTATTGGATGGTGG
ATTGTTTTAATAATCATTGAAAGTGGGATTGTAAATCGAATTATTTGCGG
TAAGTTGAAAAACTCGTATTTGAAAAGAATAGAAATCAGAAATACAGAAG
ACTTTGATGTTAATTTAGAGAGAGAAAGAATGAGTTCAGACCAAAAATCT
GATGATGTGTTAAGAGTCATTAATTTAACTAAAATCTACAATGTGTATTT
AAAATTTAAAGACAATTGTGGTGAAAAAGGAAAAGATAACTATATTAAGA
ATAAAGCCCGTGAAGTGGCTGTTAATAATCTGTGTTTTGGTGTTCGAGAA
GGCGAATGTTTCGGATTGCTCGGCGTGAATGGCGCGGGTAAAACAACGAC
TTTT

protein sequence of SMED30007539-orf-1

>SMED30007539-orf-1 ID=SMED30007539-orf-1|Name=SMED30007539-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=851bp
SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISN
SGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEE
IDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVY
GDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGL
QIKRFHYAKRNKKGIFAELILPILMITLMIALLKLVNPLESLPAMEISPW
LMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDL
GESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTG
YQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFG
GYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQNLEPLRFLKYFQEF
FNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSWNYGI
SVTNYPIADSETKISQFNNLILLEVTLAIYVILALSFISASFVIFLIDER
ISGSKRQQFVSGINPYVYWVSNFLWDIMKYIIPIIIIIIIFIAFDYQSYI
CSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGTI
TTISTFILDILEVNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFY
NSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICG
KLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYL
KFKDNCGEKGKDNYIKNKAREVAVNNLCFGVREGECFGLLGVNGAGKTTT
F

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0002032	epidermal cell
PLANA:0002089	reproductive organ
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR026082	ABCA
IPR027417	P-loop_NTPase

Vocabulary: **molecular function**
Term	Definition
GO:0000166	nucleotide binding
GO:0005102	signaling receptor binding
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0005548	phospholipid transporter activity
GO:0008509	anion transmembrane transporter activity
GO:0016887	ATPase activity
GO:0017127	cholesterol transporter activity
GO:0019905	syntaxin binding
GO:0031267	small GTPase binding
GO:0034185	apolipoprotein binding
GO:0034186	apolipoprotein A-I binding
GO:0034188	apolipoprotein A-I receptor activity
GO:0042626	ATPase activity, coupled to transmembrane movement of substances
GO:0051117	ATPase binding
GO:0090554	phosphatidylcholine-translocating ATPase activity
GO:0090556	phosphatidylserine-translocating ATPase activity

Vocabulary: **biological process**
Term	Definition
GO:0002790	peptide secretion
GO:0006497	protein lipidation
GO:0006810	transport
GO:0006911	phagocytosis, engulfment
GO:0007040	lysosome organization
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007584	response to nutrient
GO:0008203	cholesterol metabolic process
GO:0010875	positive regulation of cholesterol efflux
GO:0015914	phospholipid transport
GO:0015917	aminophospholipid transport
GO:0016197	endosomal transport
GO:0030301	cholesterol transport
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0032367	intracellular cholesterol transport
GO:0032489	regulation of Cdc42 protein signal transduction
GO:0033344	cholesterol efflux
GO:0033700	phospholipid efflux
GO:0034380	high-density lipoprotein particle assembly
GO:0034616	response to laminar fluid shear stress
GO:0038027	apolipoprotein A-I-mediated signaling pathway
GO:0042157	lipoprotein metabolic process
GO:0042158	lipoprotein biosynthetic process
GO:0042493	response to drug
GO:0042632	cholesterol homeostasis
GO:0043691	reverse cholesterol transport
GO:0045332	phospholipid translocation
GO:0050702	interleukin-1 beta secretion
GO:0055085	transmembrane transport
GO:0055091	phospholipid homeostasis
GO:0055098	response to low-density lipoprotein particle
GO:0060155	platelet dense granule organization
GO:0071222	cellular response to lipopolysaccharide
GO:0071300	cellular response to retinoic acid
GO:0071397	cellular response to cholesterol
GO:0098656	anion transmembrane transport

Vocabulary: **cellular component**
Term	Definition
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030139	endocytic vesicle
GO:0034364	high-density lipoprotein particle
GO:0043231	intracellular membrane-bounded organelle
GO:0045121	membrane raft
GO:0045335	phagocytic vesicle
GO:0048471	perinuclear region of cytoplasm

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PFAM	PF12698	ABC2_membrane_3	coord: 442..590 e-value: 1.0E-19 score: 70.9
None	No IPR available	PANTHER	PTHR19229:SF185		coord: 2..592
None	No IPR available	TMHMM	TMhelix		coord: 214..236
None	No IPR available	TMHMM	TMhelix		coord: 568..590
None	No IPR available	TMHMM	TMhelix		coord: 525..547
IPR026082	ABC transporter A	PANTHER	PTHR19229	ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA	coord: 2..592

Main menu

ATP-binding cassette sub-family A member 1

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Owlery

blazegraph-runner