Potassium voltage-gated channel subfamily KQT member 5

Overview
NamePotassium voltage-gated channel subfamily KQT member 5
Smed IDSMED30007451
Length (bp)2682
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Potassium voltage-gated channel subfamily KQT member 5 (SMED30007451) t-SNE clustered cells

Violin plots show distribution of expression levels for Potassium voltage-gated channel subfamily KQT member 5 (SMED30007451) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Potassium voltage-gated channel subfamily KQT member 5 (SMED30007451) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Potassium voltage-gated channel subfamily KQT member 5 (SMED30007451) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30007451

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30007451h1SMcG0016323 SmedASXL_014300SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30007451h1SMcG0016323 dd_Smed_v4_12681_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30007451h1SMcG0016323 dd_Smed_v4_12681_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30007451h1SMcG0016323 dd_Smed_v4_12681_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30007451h1SMcG0016323 dd_Smed_v4_12681_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30007451h1SMcG0016323 dd_Smed_v6_12681_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Human
Match: KCNQ4 (potassium voltage-gated channel subfamily Q member 4 [Source:HGNC Symbol;Acc:HGNC:6298])

HSP 1 Score: 412.92 bits (1060), Expect = 5.846e-132
Identity = 252/590 (42.71%), Postives = 340/590 (57.63%), Query Frame = 3
Query:  570 GRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSD-PQSTSVATWKPH---LKSFRASTI-------EKNTXXXXXXXXXXXXAVDRLAKFSRISTIKRRCEKLANTXXXXXXXXXXXXXXTIVLNSYNRNNGTXXXXXXXXXXXXXXXXXXXMYSTPAFSISRRNALAQSVEKYREDDQSTKKKFGILDDFFLNRYTSMASMTRDEILAE-DWDALLPKRELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGR--SDVKISEGYD---------SRISLASRIVKIETKVESMELKLDKFIQLY 2270
            G+  S    +YR+LQ+ +YN LERP+ W  V YH+ +F  VF+CLVLSVLST+ +    A E L  +E  ++  F  EY +R+WSAGC  RY+ W+GR  FAR+PFC++D +V +AS+ V+A G+   +FA SALR +RF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+F+SFL+YLAEKD      SYAD+LWWG ITL T+GYGD  P T LG+++A   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RRMPAA LIQ  WR YS+D  ++   ATW  +   L SFR   +        +N       +  +       +++  ++T    C +  +TS      S       I + S  R  G             +      M ++P+            V+K    +  T+ +  +     L   TS      +E+  E  +   L   ++    K  IR IR ++F VA RKFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + GR   D K  E  D           IS+  R+VK+E +V+S+E KLD  +  Y
Sbjct:   70 GQRSSAAHKRYRRLQNWVYNVLERPRGWAFV-YHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVAT----CHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGP----------SKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLR----LKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFY 640          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Human
Match: KCNQ5 (potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299])

HSP 1 Score: 353.984 bits (907), Expect = 5.950e-113
Identity = 182/327 (55.66%), Postives = 236/327 (72.17%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYS-----RQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKN 1505
            R SLLGKP+   SY+     R++ +YR++Q+ +YN LERP+ W  + YH  VF  VF CL+LSV ST+ +    A   L  +E  ++  F  E+ +R+WSAGC  RY+ W+GRL FAR+PFC++D +V++ASI V++  +   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EKD   +  +YADALWWG ITL T+GYGD  P T LG+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D +S S+ATWKPHLK+    +  K 
Sbjct:   86 RMSLLGKPL---SYTSSQSCRRNVKYRRVQNYLYNVLERPRGWAFI-YHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKK 408          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Human
Match: KCNQ5 (potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299])

HSP 1 Score: 363.614 bits (932), Expect = 9.531e-112
Identity = 181/323 (56.04%), Postives = 233/323 (72.14%), Query Frame = 3
Query:  540 RKSLLGKPI--VGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+        R++ +YR++Q+ +YN LERP+ W A  YH  VF  VF CL+LSV ST+ +    A   L  +E  ++  F  E+ +R+WSAGC  RY+ W+GRL FAR+PFC++D +V++ASI V++  +   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EKD   +  +YADALWWG ITL T+GYGD  P T LG+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D +S S+ATWKPHLK+    +  K
Sbjct:   86 RMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGW-AFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTK 407          

HSP 2 Score: 100.908 bits (250), Expect = 3.802e-21
Identity = 48/103 (46.60%), Postives = 72/103 (69.90%), Query Frame = 3
Query: 1995 RKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDV--------KISEGYDSR--ISLASRIVKIETKVESMELKLDKFIQLYK 2273
            R ++F VA RKFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  +        KI+  +++   +S+  R+VK+E +V+S+E KLD  + +Y+
Sbjct:  416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQ 518          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Human
Match: KCNQ5 (potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299])

HSP 1 Score: 363.614 bits (932), Expect = 1.015e-111
Identity = 181/323 (56.04%), Postives = 233/323 (72.14%), Query Frame = 3
Query:  540 RKSLLGKPI--VGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+        R++ +YR++Q+ +YN LERP+ W A  YH  VF  VF CL+LSV ST+ +    A   L  +E  ++  F  E+ +R+WSAGC  RY+ W+GRL FAR+PFC++D +V++ASI V++  +   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EKD   +  +YADALWWG ITL T+GYGD  P T LG+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D +S S+ATWKPHLK+    +  K
Sbjct:   86 RMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGW-AFIYHAFVFLPVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTK 407          

HSP 2 Score: 100.908 bits (250), Expect = 3.737e-21
Identity = 48/103 (46.60%), Postives = 72/103 (69.90%), Query Frame = 3
Query: 1995 RKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDV--------KISEGYDSR--ISLASRIVKIETKVESMELKLDKFIQLYK 2273
            R ++F VA RKFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  +        KI+  +++   +S+  R+VK+E +V+S+E KLD  + +Y+
Sbjct:  416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQ 518          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Human
Match: KCNQ5 (potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299])

HSP 1 Score: 364.385 bits (934), Expect = 6.403e-111
Identity = 181/323 (56.04%), Postives = 233/323 (72.14%), Query Frame = 3
Query:  540 RKSLLGKPI--VGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+        R++ +YR++Q+ +YN LERP+ W A  YH  VF  VF CL+LSV ST+ +    A   L  +E  ++  F  E+ +R+WSAGC  RY+ W+GRL FAR+PFC++D +V++ASI V++  +   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EKD   +  +YADALWWG ITL T+GYGD  P T LG+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D +S S+ATWKPHLK+    +  K
Sbjct:   86 RMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGW-AFIYHAFVFLPVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTK 407          

HSP 2 Score: 107.842 bits (268), Expect = 3.550e-23
Identity = 53/116 (45.69%), Postives = 79/116 (68.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDV--------KISEGYDSR--ISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +L+   K  IR IR ++F VA RKFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  +        KI+  +++   +S+  R+VK+E +V+S+E KLD  + +Y+
Sbjct:  513 DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQ 628          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Celegans
Match: kqt-1 (KQT-1 potassium channel; Potassium channel, KvQLT family [Source:UniProtKB/TrEMBL;Acc:G5EDN5])

HSP 1 Score: 410.609 bits (1054), Expect = 1.802e-131
Identity = 198/311 (63.67%), Postives = 247/311 (79.42%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHL 1472
            + SL+GKP+  ++Y R D ++R++Q+K++NFLERP+ W A  YH+ V   V  CL LSV ST+ D    A  +L+Y+E+  + W  TEY  R+WSAGCRSRY+   GR+ FA   +C++D++VILASI VL +G+  Q+FAASA+RGLRFFQILRM+R+DRR G+WKLL SVVWAHRQEL TT+YIGFL L+FSSFL+YL EK+  DK +++ADALWWGVITL TVGYGD  P+T  GK+IA  CA+ GISFFALPAGILGSGFALKVQQHQR KHLIRRR+PAA LIQCLWR YS+ P+STS+ATWK HL
Sbjct:   63 KMSLVGKPLTYKNY-RTDQRFRRMQNKMHNFLERPRGWKAATYHLAVLFMVLMCLALSVFSTMPDFEVNATIVLYYLEIVFVIWLATEYICRVWSAGCRSRYRGISGRIRFATSAYCVIDIIVILASITVLCIGATGQVFAASAIRGLRFFQILRMLRIDRRAGTWKLLGSVVWAHRQELLTTVYIGFLGLIFSSFLVYLCEKNTNDKYQTFADALWWGVITLSTVGYGDKTPETWPGKIIAAFCALLGISFFALPAGILGSGFALKVQQHQRQKHLIRRRVPAAKLIQCLWRHYSAAPESTSLATWKIHL 372          

HSP 2 Score: 98.5969 bits (244), Expect = 6.657e-21
Identity = 46/104 (44.23%), Postives = 74/104 (71.15%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQL 2267
            E +   K+ +R IR+++  VA +KFKEAL+PYD+KD+IEQYS+GHVD+ +R+K +Q +LD + G++  KI    + +IS+ +RI  +ET V  M+ KLD  +++
Sbjct:  500 EFTPALKNCVRAIRRIQLLVARKKFKEALKPYDVKDVIEQYSAGHVDLQSRVKTVQAKLDFICGKNIEKI----EPKISMFTRIATLETTVGKMDKKLDLMVEM 599          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Celegans
Match: kqt-1 (KQT-1 potassium channel; Potassium channel, KvQLT family [Source:UniProtKB/TrEMBL;Acc:G5EDN5])

HSP 1 Score: 409.453 bits (1051), Expect = 1.529e-130
Identity = 198/311 (63.67%), Postives = 247/311 (79.42%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHL 1472
            + SL+GKP+  ++Y R D ++R++Q+K++NFLERP+ W A  YH+ V   V  CL LSV ST+ D    A  +L+Y+E+  + W  TEY  R+WSAGCRSRY+   GR+ FA   +C++D++VILASI VL +G+  Q+FAASA+RGLRFFQILRM+R+DRR G+WKLL SVVWAHRQEL TT+YIGFL L+FSSFL+YL EK+  DK +++ADALWWGVITL TVGYGD  P+T  GK+IA  CA+ GISFFALPAGILGSGFALKVQQHQR KHLIRRR+PAA LIQCLWR YS+ P+STS+ATWK HL
Sbjct:  111 KMSLVGKPLTYKNY-RTDQRFRRMQNKMHNFLERPRGWKAATYHLAVLFMVLMCLALSVFSTMPDFEVNATIVLYYLEIVFVIWLATEYICRVWSAGCRSRYRGISGRIRFATSAYCVIDIIVILASITVLCIGATGQVFAASAIRGLRFFQILRMLRIDRRAGTWKLLGSVVWAHRQELLTTVYIGFLGLIFSSFLVYLCEKNTNDKYQTFADALWWGVITLSTVGYGDKTPETWPGKIIAAFCALLGISFFALPAGILGSGFALKVQQHQRQKHLIRRRVPAAKLIQCLWRHYSAAPESTSLATWKIHL 420          

HSP 2 Score: 98.9821 bits (245), Expect = 6.308e-21
Identity = 46/104 (44.23%), Postives = 74/104 (71.15%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQL 2267
            E +   K+ +R IR+++  VA +KFKEAL+PYD+KD+IEQYS+GHVD+ +R+K +Q +LD + G++  KI    + +IS+ +RI  +ET V  M+ KLD  +++
Sbjct:  548 EFTPALKNCVRAIRRIQLLVARKKFKEALKPYDVKDVIEQYSAGHVDLQSRVKTVQAKLDFICGKNIEKI----EPKISMFTRIATLETTVGKMDKKLDLMVEM 647          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Celegans
Match: kqt-3 (Potassium channel, KvQLT family [Source:UniProtKB/TrEMBL;Acc:B7FAS2])

HSP 1 Score: 335.88 bits (860), Expect = 2.090e-104
Identity = 172/320 (53.75%), Postives = 228/320 (71.25%), Query Frame = 3
Query:  591 DAQYRKLQSK----------IYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDE-----RDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKN 1505
            +A+YR ++ K          IYN LERP  W    YH  VF  V  CL+LSVLSTV++  ++A E+L+ +E+ ++ +F  E+ +RLWSAGCRS+Y    GRL F R+P  L+DLVV++ S+ V+  G++ Q+FAASA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD      R    SYADALWWGVIT+ T+GYGD VP+T LG+++A C +I  ISFFALPAGILGSGFALKVQQ QR KH  R+   AATLIQCLWRC++++ + +  ATW  H+      T E +
Sbjct:    3 NARYRNIKEKKAAKMTYRAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDHIGVDGRQAFTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAAEKKVS--ATWNAHIDPLAHETKETH 320          

HSP 2 Score: 91.2781 bits (225), Expect = 9.206e-19
Identity = 43/103 (41.75%), Postives = 74/103 (71.84%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSR----ISLASRIVKIETKVESMELKLD 2252
            EL++  ++AIR IR+V++FVA R+F++A +PYD++D+IEQYS GH++M+ RIK LQ RLD   G+      +G  SR    +++ SR+ ++E ++ S++ K++
Sbjct:  419 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQ--YDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 519          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Celegans
Match: kqt-3 (Potassium channel, KvQLT family [Source:UniProtKB/TrEMBL;Acc:B7FAS2])

HSP 1 Score: 335.88 bits (860), Expect = 2.090e-104
Identity = 172/320 (53.75%), Postives = 228/320 (71.25%), Query Frame = 3
Query:  591 DAQYRKLQSK----------IYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDE-----RDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKN 1505
            +A+YR ++ K          IYN LERP  W    YH  VF  V  CL+LSVLSTV++  ++A E+L+ +E+ ++ +F  E+ +RLWSAGCRS+Y    GRL F R+P  L+DLVV++ S+ V+  G++ Q+FAASA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD      R    SYADALWWGVIT+ T+GYGD VP+T LG+++A C +I  ISFFALPAGILGSGFALKVQQ QR KH  R+   AATLIQCLWRC++++ + +  ATW  H+      T E +
Sbjct:    3 NARYRNIKEKKAAKMTYRAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDHIGVDGRQAFTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAAEKKVS--ATWNAHIDPLAHETKETH 320          

HSP 2 Score: 91.2781 bits (225), Expect = 9.206e-19
Identity = 43/103 (41.75%), Postives = 74/103 (71.84%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSR----ISLASRIVKIETKVESMELKLD 2252
            EL++  ++AIR IR+V++FVA R+F++A +PYD++D+IEQYS GH++M+ RIK LQ RLD   G+      +G  SR    +++ SR+ ++E ++ S++ K++
Sbjct:  419 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQ--YDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 519          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Celegans
Match: kqt-3 (Potassium channel, KvQLT family [Source:UniProtKB/TrEMBL;Acc:B7FAS2])

HSP 1 Score: 336.265 bits (861), Expect = 4.288e-104
Identity = 172/320 (53.75%), Postives = 228/320 (71.25%), Query Frame = 3
Query:  591 DAQYRKLQSK----------IYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDE-----RDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKN 1505
            +A+YR ++ K          IYN LERP  W    YH  VF  V  CL+LSVLSTV++  ++A E+L+ +E+ ++ +F  E+ +RLWSAGCRS+Y    GRL F R+P  L+DLVV++ S+ V+  G++ Q+FAASA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD      R    SYADALWWGVIT+ T+GYGD VP+T LG+++A C +I  ISFFALPAGILGSGFALKVQQ QR KH  R+   AATLIQCLWRC++++ + +  ATW  H+      T E +
Sbjct:   44 NARYRNIKEKKAAKMTYRAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDHIGVDGRQAFTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAAEKKVS--ATWNAHIDPLAHETKETH 361          

HSP 2 Score: 91.2781 bits (225), Expect = 9.843e-19
Identity = 43/103 (41.75%), Postives = 74/103 (71.84%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSR----ISLASRIVKIETKVESMELKLD 2252
            EL++  ++AIR IR+V++FVA R+F++A +PYD++D+IEQYS GH++M+ RIK LQ RLD   G+      +G  SR    +++ SR+ ++E ++ S++ K++
Sbjct:  460 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQY--DGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 560          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Fly
Match: KCNQ (gene:FBgn0033494 transcript:FBtr0299832)

HSP 1 Score: 421.009 bits (1081), Expect = 1.497e-135
Identity = 208/324 (64.20%), Postives = 254/324 (78.40%), Query Frame = 3
Query:  498 RSNSKELPNMHFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPH 1469
            R NS+ +      PR SLLGKP+     +R+D +YR+LQS++YNFLERP+  +A+ YH++VF  VFTCL LSV ST+ +    A  +LF +E+ V+ WF  E+  RLWS+GCRSRYQ   GRL F ++PFC++D+V ILASI+VL +G+  Q+FA SALRGLRFFQILRM+RMDRRGG+WKLL SVV+AHRQEL TT+YIGFL L+F+SFL+Y+ EKD  DK  ++A ALWWGVITLCTVGYGD VP T  GKLIA CCA+ GISFFALPAGILGSGFALKVQQ QR KH+IRRR PAATLIQ +WRCY++D  S SVATW  H
Sbjct:   24 RPNSERI----LQPRMSLLGKPLNYNRGTRRDVRYRRLQSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 343          

HSP 2 Score: 130.568 bits (327), Expect = 6.672e-31
Identity = 60/105 (57.14%), Postives = 82/105 (78.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQLY 2270
            +L+N  K AIRFIRK+++FVA RKFKEAL+PYD+KD++EQY++GHVD+L R+K L LRLD + G+   K  + Y S+ISLASR+VK+E +V  +E KLD  I+ Y
Sbjct:  428 QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGKQGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAY 532          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Fly
Match: KCNQ (gene:FBgn0033494 transcript:FBtr0310093)

HSP 1 Score: 423.32 bits (1087), Expect = 5.991e-135
Identity = 208/324 (64.20%), Postives = 254/324 (78.40%), Query Frame = 3
Query:  498 RSNSKELPNMHFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPH 1469
            R NS+ +      PR SLLGKP+     +R+D +YR+LQS++YNFLERP+  +A+ YH++VF  VFTCL LSV ST+ +    A  +LF +E+ V+ WF  E+  RLWS+GCRSRYQ   GRL F ++PFC++D+V ILASI+VL +G+  Q+FA SALRGLRFFQILRM+RMDRRGG+WKLL SVV+AHRQEL TT+YIGFL L+F+SFL+Y+ EKD  DK  ++A ALWWGVITLCTVGYGD VP T  GKLIA CCA+ GISFFALPAGILGSGFALKVQQ QR KH+IRRR PAATLIQ +WRCY++D  S SVATW  H
Sbjct:   21 RPNSERI----LQPRMSLLGKPLNYNRGTRRDVRYRRLQSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 340          

HSP 2 Score: 130.954 bits (328), Expect = 8.664e-31
Identity = 60/105 (57.14%), Postives = 82/105 (78.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQLY 2270
            +L+N  K AIRFIRK+++FVA RKFKEAL+PYD+KD++EQY++GHVD+L R+K L LRLD + G+   K  + Y S+ISLASR+VK+E +V  +E KLD  I+ Y
Sbjct:  425 QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGKQGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAY 529          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Fly
Match: KCNQ (gene:FBgn0033494 transcript:FBtr0310095)

HSP 1 Score: 424.476 bits (1090), Expect = 6.444e-135
Identity = 208/324 (64.20%), Postives = 254/324 (78.40%), Query Frame = 3
Query:  498 RSNSKELPNMHFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPH 1469
            R NS+ +      PR SLLGKP+     +R+D +YR+LQS++YNFLERP+  +A+ YH++VF  VFTCL LSV ST+ +    A  +LF +E+ V+ WF  E+  RLWS+GCRSRYQ   GRL F ++PFC++D+V ILASI+VL +G+  Q+FA SALRGLRFFQILRM+RMDRRGG+WKLL SVV+AHRQEL TT+YIGFL L+F+SFL+Y+ EKD  DK  ++A ALWWGVITLCTVGYGD VP T  GKLIA CCA+ GISFFALPAGILGSGFALKVQQ QR KH+IRRR PAATLIQ +WRCY++D  S SVATW  H
Sbjct:   24 RPNSERI----LQPRMSLLGKPLNYNRGTRRDVRYRRLQSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 343          

HSP 2 Score: 130.954 bits (328), Expect = 8.199e-31
Identity = 60/105 (57.14%), Postives = 82/105 (78.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQLY 2270
            +L+N  K AIRFIRK+++FVA RKFKEAL+PYD+KD++EQY++GHVD+L R+K L LRLD + G+   K  + Y S+ISLASR+VK+E +V  +E KLD  I+ Y
Sbjct:  459 QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGKQGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAY 563          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Fly
Match: KCNQ (gene:FBgn0033494 transcript:FBtr0301443)

HSP 1 Score: 423.32 bits (1087), Expect = 8.278e-135
Identity = 208/324 (64.20%), Postives = 254/324 (78.40%), Query Frame = 3
Query:  498 RSNSKELPNMHFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPH 1469
            R NS+ +      PR SLLGKP+     +R+D +YR+LQS++YNFLERP+  +A+ YH++VF  VFTCL LSV ST+ +    A  +LF +E+ V+ WF  E+  RLWS+GCRSRYQ   GRL F ++PFC++D+V ILASI+VL +G+  Q+FA SALRGLRFFQILRM+RMDRRGG+WKLL SVV+AHRQEL TT+YIGFL L+F+SFL+Y+ EKD  DK  ++A ALWWGVITLCTVGYGD VP T  GKLIA CCA+ GISFFALPAGILGSGFALKVQQ QR KH+IRRR PAATLIQ +WRCY++D  S SVATW  H
Sbjct:   24 RPNSERI----LQPRMSLLGKPLNYNRGTRRDVRYRRLQSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 343          

HSP 2 Score: 130.954 bits (328), Expect = 9.203e-31
Identity = 60/105 (57.14%), Postives = 82/105 (78.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQLY 2270
            +L+N  K AIRFIRK+++FVA RKFKEAL+PYD+KD++EQY++GHVD+L R+K L LRLD + G+   K  + Y S+ISLASR+VK+E +V  +E KLD  I+ Y
Sbjct:  428 QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGKQGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAY 532          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Fly
Match: KCNQ (gene:FBgn0033494 transcript:FBtr0310096)

HSP 1 Score: 423.32 bits (1087), Expect = 1.108e-134
Identity = 208/324 (64.20%), Postives = 254/324 (78.40%), Query Frame = 3
Query:  498 RSNSKELPNMHFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPH 1469
            R NS+ +      PR SLLGKP+     +R+D +YR+LQS++YNFLERP+  +A+ YH++VF  VFTCL LSV ST+ +    A  +LF +E+ V+ WF  E+  RLWS+GCRSRYQ   GRL F ++PFC++D+V ILASI+VL +G+  Q+FA SALRGLRFFQILRM+RMDRRGG+WKLL SVV+AHRQEL TT+YIGFL L+F+SFL+Y+ EKD  DK  ++A ALWWGVITLCTVGYGD VP T  GKLIA CCA+ GISFFALPAGILGSGFALKVQQ QR KH+IRRR PAATLIQ +WRCY++D  S SVATW  H
Sbjct:   24 RPNSERI----LQPRMSLLGKPLNYNRGTRRDVRYRRLQSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 343          

HSP 2 Score: 130.954 bits (328), Expect = 8.772e-31
Identity = 60/105 (57.14%), Postives = 82/105 (78.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQLY 2270
            +L+N  K AIRFIRK+++FVA RKFKEAL+PYD+KD++EQY++GHVD+L R+K L LRLD + G+   K  + Y S+ISLASR+VK+E +V  +E KLD  I+ Y
Sbjct:  447 QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGKQGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAY 551          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Zebrafish
Match: kcnq5a (potassium voltage-gated channel, KQT-like subfamily, member 5a [Source:ZFIN;Acc:ZDB-GENE-090312-185])

HSP 1 Score: 370.933 bits (951), Expect = 1.308e-113
Identity = 185/315 (58.73%), Postives = 236/315 (74.92%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYS-RQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSF 1481
            R SLLGKP+   + S R++A+YRKLQ+ +YN LERP+ W  V YH  VF  VF CLVLSV ST+    + +   L  +E  ++  F  EY +R+WSAGC  RY+ W+GRL FAR+PFC++D++V++ASI V++ GS   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EK+   +  +YADALWWG ITL T+GYGD  P+T  G+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA+LIQC+WR Y++D  S S+ATWKPHLK+ 
Sbjct:   66 RLSLLGKPLAYSAQSGRRNARYRKLQNYLYNVLERPRAWAFV-YHAFVFTLVFGCLVLSVFSTIPAHMDLSNHCLLILEFVMIVVFGLEYIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLIASIAVVSAGSQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKQFATYADALWWGTITLTTIGYGDKTPQTWTGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAASLIQCVWRSYAADENSVSIATWKPHLKAL 379          

HSP 2 Score: 108.227 bits (269), Expect = 1.490e-23
Identity = 51/117 (43.59%), Postives = 75/117 (64.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKI-----------SEGYDSRISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +LS   K  IR IR ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  + +            E  +  +S+  R+ K+E +V+S+E KLD  + +Y+
Sbjct:  483 DLSAPLKAVIRAIRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQISVDRKGREKILPEGESLEHDMSMLGRVCKVERQVQSIESKLDSLLDIYR 599          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Zebrafish
Match: kcnq5b (potassium voltage-gated channel, KQT-like subfamily, member 5b [Source:ZFIN;Acc:ZDB-GENE-090312-178])

HSP 1 Score: 371.703 bits (953), Expect = 1.412e-113
Identity = 185/322 (57.45%), Postives = 237/322 (73.60%), Query Frame = 3
Query:  540 RKSLLGKPIV-GRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+V G    R++A+YR++Q+ +YN LERP++W  + YH  VF  VF CLVLSV ST+ D    A + L  +E  ++  F  EY +R+WSAGC  RY+ W+GRL FAR+PFC++D++V++AS+ V++ GS   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EK+      +YADALWWG ITL T+GYGD  PKT  G++++   A+ GISFF LPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D  S SVATWKPHLK+    +  K
Sbjct:   72 RLSLLGKPLVYGTQSGRRNARYRRIQNYLYNVLERPRSWAFI-YHAFVFVLVFGCLVLSVFSTIPDHQEMASQSLLILEFVMIVVFGLEYIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLIASVAVVSAGSQSNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKDFATYADALWWGTITLTTIGYGDKTPKTWTGRMLSAGFALLGISFFTLPAGILGSGFALKVQEQHRQKHFEKRRNPAACLIQCVWRSYAADENSVSVATWKPHLKALHTCSPTK 392          

HSP 2 Score: 107.071 bits (266), Expect = 4.403e-23
Identity = 54/137 (39.42%), Postives = 83/137 (60.58%), Query Frame = 3
Query: 1896 ASMTRDEILAE-DWDALLPKRELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSR----------ISLASRIVKIETKVESMELKLDKFIQLYK 2273
            A++T DE   E      +   +L +  K  IR +R ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + GR  + + +    +          +S+  R+ K+E +V+S+E KLD  + +Y+
Sbjct:  477 ANVTVDEAFDEKGCHCDMSVEDLPSALKTVIRAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGRGQMPVDKKVREKLLSDGDILEDVSMLGRVCKVERQVQSIESKLDSLLDIYR 613          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Zebrafish
Match: kcnq1.1 (potassium voltage-gated channel, KQT-like subfamily, member 1.1 [Source:ZFIN;Acc:ZDB-GENE-061214-5])

HSP 1 Score: 334.339 bits (856), Expect = 9.285e-105
Identity = 180/327 (55.05%), Postives = 232/327 (70.95%), Query Frame = 3
Query:  519 PNMHFVPRKSLLG--KPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDK-----IKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYS-SDPQSTSVATWKPHLK 1475
            P  H  PR S+    +P + RS+         LQ ++YNFLERP  W    YH  VF  V +CL+LSVLST+D+    A + LF++EL ++ +F  EY +RLWSAGCRS+Y    GRL FAR+P  ++DL+V++ASIIVLA GS+ Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD  D        SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA+LIQ  WRC++  +P S   AT+K  +K
Sbjct:   51 PPSHLHPRMSVYSATRPTLSRSF---------LQGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGNSGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDS---ATYKLFVK 365          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Zebrafish
Match: kcnq1.1 (potassium voltage-gated channel, KQT-like subfamily, member 1.1 [Source:ZFIN;Acc:ZDB-GENE-061214-5])

HSP 1 Score: 338.576 bits (867), Expect = 1.942e-104
Identity = 180/327 (55.05%), Postives = 232/327 (70.95%), Query Frame = 3
Query:  519 PNMHFVPRKSLLG--KPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDK-----IKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYS-SDPQSTSVATWKPHLK 1475
            P  H  PR S+    +P + RS+         LQ ++YNFLERP  W    YH  VF  V +CL+LSVLST+D+    A + LF++EL ++ +F  EY +RLWSAGCRS+Y    GRL FAR+P  ++DL+V++ASIIVLA GS+ Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD  D        SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA+LIQ  WRC++  +P S   AT+K  +K
Sbjct:   51 PPSHLHPRMSVYSATRPTLSRSF---------LQGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGNSGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDS---ATYKLFVK 365          

HSP 2 Score: 78.1814 bits (191), Expect = 2.471e-14
Identity = 45/141 (31.91%), Postives = 84/141 (59.57%), Query Frame = 3
Query: 1887 TSMASMTRDEILAEDWDALLPKRE-----------LSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDV--KISEGYDSRI--SLASRIVKIETKVESMELKLDKFIQ 2264
            +S  ++ R   +A+D +   P+RE           L ++ + AIR I+++ +FVA +KF++A +PYD++D+IEQYS GH++++ RIK LQ RLD+  G+  +    SE    +   ++ SR+ +++ K+  M+  L+   +
Sbjct:  452 SSRPTLQRSSSIADDMETE-PEREIVLIPVAHVSQLRDSHRAAIRVIQRMYYFVARKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDHSLGKQSLFQTSSERLKDKGTNTIGSRLNRMDEKITHMDRTLNSIAE 591          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Zebrafish
Match: kcnq1.1 (potassium voltage-gated channel, KQT-like subfamily, member 1.1 [Source:ZFIN;Acc:ZDB-GENE-061214-5])

HSP 1 Score: 338.191 bits (866), Expect = 2.960e-104
Identity = 180/327 (55.05%), Postives = 232/327 (70.95%), Query Frame = 3
Query:  519 PNMHFVPRKSLLG--KPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDK-----IKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYS-SDPQSTSVATWKPHLK 1475
            P  H  PR S+    +P + RS+         LQ ++YNFLERP  W    YH  VF  V +CL+LSVLST+D+    A + LF++EL ++ +F  EY +RLWSAGCRS+Y    GRL FAR+P  ++DL+V++ASIIVLA GS+ Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD  D        SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA+LIQ  WRC++  +P S   AT+K  +K
Sbjct:   51 PPSHLHPRMSVYSATRPTLSRSF---------LQGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGNSGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDS---ATYKLFVK 365          

HSP 2 Score: 78.1814 bits (191), Expect = 2.560e-14
Identity = 45/141 (31.91%), Postives = 84/141 (59.57%), Query Frame = 3
Query: 1887 TSMASMTRDEILAEDWDALLPKRE-----------LSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDV--KISEGYDSRI--SLASRIVKIETKVESMELKLDKFIQ 2264
            +S  ++ R   +A+D +   P+RE           L ++ + AIR I+++ +FVA +KF++A +PYD++D+IEQYS GH++++ RIK LQ RLD+  G+  +    SE    +   ++ SR+ +++ K+  M+  L+   +
Sbjct:  464 SSRPTLQRSSSIADDMETE-PEREIVLIPVAHVSQLRDSHRAAIRVIQRMYYFVARKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDHSLGKQSLFQTSSERLKDKGTNTIGSRLNRMDEKITHMDRTLNSIAE 603          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Xenopus
Match: ENSXETT00000046831.1 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:100492908])

HSP 1 Score: 338.961 bits (868), Expect = 5.182e-108
Identity = 169/293 (57.68%), Postives = 222/293 (75.77%), Query Frame = 3
Query:  609 LQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDK-----IKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHL 1472
            +Q  IYNFLERP  W    YH  VF  V  CL+ SVLST++    +A   LF++E+ ++ +F  EY +RLWSAGCRS+Y  ++GR+ FAR+P  ++DL+V++ASIIVL++GS+ Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD  D+       SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA+LIQ LWRCY+++   +S ATWK +L
Sbjct:   56 MQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAEYLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDEEGRTGFSSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYAAEKSYSSTATWKIYL 348          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Xenopus
Match: ENSXETT00000046823.1 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:100492908])

HSP 1 Score: 340.887 bits (873), Expect = 2.025e-107
Identity = 169/293 (57.68%), Postives = 222/293 (75.77%), Query Frame = 3
Query:  609 LQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDK-----IKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHL 1472
            +Q  IYNFLERP  W    YH  VF  V  CL+ SVLST++    +A   LF++E+ ++ +F  EY +RLWSAGCRS+Y  ++GR+ FAR+P  ++DL+V++ASIIVL++GS+ Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD  D+       SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA+LIQ LWRCY+++   +S ATWK +L
Sbjct:   85 MQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAEYLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDEEGRTGFSSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYAAEKSYSSTATWKIYL 377          

HSP 2 Score: 70.0922 bits (170), Expect = 6.951e-12
Identity = 30/62 (48.39%), Postives = 49/62 (79.03%), Query Frame = 3
Query: 1950 KRELSNTEKH--AIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLR 2129
            ++++  TE H  A++  R++++FVA RKF++A +PYD++D+IEQYS GH++M+ RIK LQ R
Sbjct:  396 RKQVRLTEAHRMAVKVTRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR 457          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Xenopus
Match: kri1 (KRI1 homolog [Source:Xenbase;Acc:XB-GENE-6036517])

HSP 1 Score: 338.576 bits (867), Expect = 2.887e-106
Identity = 176/327 (53.82%), Postives = 233/327 (71.25%), Query Frame = 3
Query:  519 PNMHFVPRKSLLG--KPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERD-----KIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSD-PQSTSVATWKPHLK 1475
            P ++  PR S+    +P++ R+          +Q ++YNFLERP  W    YH  VF  V  CL+ SVLST+    N A E LF++E+ ++ +F  EY +RLWSAGCRS+Y    GRL FAR+P  ++DL+V++ASIIVL +GS+ Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD  D     +  SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA+LIQ  WRCY+++ P S   ATWK +++
Sbjct:   80 PTINLDPRVSIYSGRRPLLTRT---------NIQGRVYNFLERPTGWKCFVYHFTVFLIVLICLIFSVLSTIQQYNNLATETLFWMEIVLVVFFGAEYVVRLWSAGCRSKYVGIWGRLRFARKPISVIDLIVVVASIIVLCVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAIDSSGEYQFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIYIR 394          

HSP 2 Score: 68.5514 bits (166), Expect = 2.519e-11
Identity = 28/58 (48.28%), Postives = 45/58 (77.59%), Query Frame = 3
Query: 1959 LSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRL 2132
            L    + AI+ IR++++FVA +KF++A +PYD++D+IEQYS GH++++ RIK LQ R 
Sbjct:  430 LKEHHRAAIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRF 487          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Xenopus
Match: ENSXETT00000046791.1 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:100492908])

HSP 1 Score: 343.584 bits (880), Expect = 3.183e-106
Identity = 169/293 (57.68%), Postives = 222/293 (75.77%), Query Frame = 3
Query:  609 LQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDK-----IKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHL 1472
            +Q  IYNFLERP  W    YH  VF  V  CL+ SVLST++    +A   LF++E+ ++ +F  EY +RLWSAGCRS+Y  ++GR+ FAR+P  ++DL+V++ASIIVL++GS+ Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD  D+       SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA+LIQ LWRCY+++   +S ATWK +L
Sbjct:   85 MQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAEYLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDEEGRTGFSSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYAAEKSYSSTATWKIYL 377          

HSP 2 Score: 95.5153 bits (236), Expect = 1.260e-19
Identity = 49/139 (35.25%), Postives = 88/139 (63.31%), Query Frame = 3
Query: 1890 SMASMTRDEILAEDWDAL-----LPK----RELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISE-GYD-SRISLASRIVKIETKVESMELKLDKFIQLYK 2273
            S+  ++R     +D D +     LP      +L+   + A++  R++++FVA RKF++A +PYD++D+IEQYS GH++M+ RIK LQ RLD+  G+  + + E G D    ++ SR++++E KV  M+ KLD+ + +++
Sbjct:  473 SLPDISRTNSYTDDIDGISEESALPAVTDLSQLTEAHRMAVKVTRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDHSLGKPGLFLPEKGVDKGYYTVGSRLMRLEEKVNRMDHKLDEILCVFR 611          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Xenopus
Match: kri1 (KRI1 homolog [Source:Xenbase;Acc:XB-GENE-6036517])

HSP 1 Score: 342.428 bits (877), Expect = 3.449e-106
Identity = 176/327 (53.82%), Postives = 233/327 (71.25%), Query Frame = 3
Query:  519 PNMHFVPRKSLLG--KPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERD-----KIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSD-PQSTSVATWKPHLK 1475
            P ++  PR S+    +P++ R+          +Q ++YNFLERP  W    YH  VF  V  CL+ SVLST+    N A E LF++E+ ++ +F  EY +RLWSAGCRS+Y    GRL FAR+P  ++DL+V++ASIIVL +GS+ Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD  D     +  SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA+LIQ  WRCY+++ P S   ATWK +++
Sbjct:   80 PTINLDPRVSIYSGRRPLLTRT---------NIQGRVYNFLERPTGWKCFVYHFTVFLIVLICLIFSVLSTIQQYNNLATETLFWMEIVLVVFFGAEYVVRLWSAGCRSKYVGIWGRLRFARKPISVIDLIVVVASIIVLCVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAIDSSGEYQFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIYIR 394          

HSP 2 Score: 69.3218 bits (168), Expect = 1.641e-11
Identity = 40/104 (38.46%), Postives = 65/104 (62.50%), Query Frame = 3
Query: 1806 SVEKYREDDQSTKKKFGILDDFFLNRYTSMASMTRDEILAEDWDALL-PKRELSNTEKH---AIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLA 2105
            SVE Y   + + +K FG LD      +   +S T D  L  + D LL P   +S  ++H   AI+ IR++++FVA +KF++A +PYD++D+IEQYS GH++++ 
Sbjct:  453 SVEAY---ENTVRKPFGFLDPG-TGPFIRTSSFTDD--LDMEGDTLLTPITHISELKEHHRAAIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMV 550          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Mouse
Match: Kcnq5 (potassium voltage-gated channel, subfamily Q, member 5 [Source:MGI Symbol;Acc:MGI:1924937])

HSP 1 Score: 363.999 bits (933), Expect = 4.191e-112
Identity = 181/323 (56.04%), Postives = 233/323 (72.14%), Query Frame = 3
Query:  540 RKSLLGKPI--VGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+        R++ +YR++Q+ +YN LERP+ W  V YH  VF  VF CL+LSV ST+ +    A   L  +E  ++  F  E+ +R+WSAGC  RY+ W+GRL FAR+PFC++D +V++ASI V++  +   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EKD   +  +YADALWWG ITL T+GYGD  P T LG+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D +S S+ATWKPHLK+    +  K
Sbjct:   87 RMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGWAFV-YHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTK 408          

HSP 2 Score: 98.9821 bits (245), Expect = 1.263e-20
Identity = 48/103 (46.60%), Postives = 72/103 (69.90%), Query Frame = 3
Query: 1995 RKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDV--------KISEGYDSR--ISLASRIVKIETKVESMELKLDKFIQLYK 2273
            R ++F VA RKFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  +        KI+  +++    S+ +R+VK+E +V+S+E KLD  + +Y+
Sbjct:  417 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQMTSDKKSREKITAEHETTDDPSMLARVVKVEKQVQSIESKLDCLLDIYQ 519          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Mouse
Match: Kcnq5 (potassium voltage-gated channel, subfamily Q, member 5 [Source:MGI Symbol;Acc:MGI:1924937])

HSP 1 Score: 365.155 bits (936), Expect = 2.268e-111
Identity = 181/323 (56.04%), Postives = 233/323 (72.14%), Query Frame = 3
Query:  540 RKSLLGKPI--VGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+        R++ +YR++Q+ +YN LERP+ W  V YH  VF  VF CL+LSV ST+ +    A   L  +E  ++  F  E+ +R+WSAGC  RY+ W+GRL FAR+PFC++D +V++ASI V++  +   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EKD   +  +YADALWWG ITL T+GYGD  P T LG+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D +S S+ATWKPHLK+    +  K
Sbjct:   87 RMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGWAFV-YHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTK 408          

HSP 2 Score: 105.531 bits (262), Expect = 1.079e-22
Identity = 53/116 (45.69%), Postives = 79/116 (68.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDV--------KISEGYDSR--ISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +L+   K  IR IR ++F VA RKFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  +        KI+  +++    S+ +R+VK+E +V+S+E KLD  + +Y+
Sbjct:  514 DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQMTSDKKSREKITAEHETTDDPSMLARVVKVEKQVQSIESKLDCLLDIYQ 629          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Mouse
Match: Kcnq5 (potassium voltage-gated channel, subfamily Q, member 5 [Source:MGI Symbol;Acc:MGI:1924937])

HSP 1 Score: 365.155 bits (936), Expect = 2.713e-111
Identity = 190/359 (52.92%), Postives = 248/359 (69.08%), Query Frame = 3
Query:  540 RKSLLGKPI--VGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKNTXXXXXXXXXXXXAVDRLAKFSRISTIKRRCEKLA 1610
            R SLLGKP+        R++ +YR++Q+ +YN LERP+ W  V YH  VF  VF CL+LSV ST+ +    A   L  +E  ++  F  E+ +R+WSAGC  RY+ W+GRL FAR+PFC++D +V++ASI V++  +   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EKD   +  +YADALWWG ITL T+GYGD  P T LG+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D +S S+ATWKPHLK+    +  K   G  SS            KF R+ T +++ +KL+
Sbjct:   87 RMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGWAFV-YHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSKF----CSNKQKFFRVYTSRKQSQKLS 440          

HSP 2 Score: 105.531 bits (262), Expect = 1.240e-22
Identity = 53/116 (45.69%), Postives = 79/116 (68.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDV--------KISEGYDSR--ISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +L+   K  IR IR ++F VA RKFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  +        KI+  +++    S+ +R+VK+E +V+S+E KLD  + +Y+
Sbjct:  533 DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQMTSDKKSREKITAEHETTDDPSMLARVVKVEKQVQSIESKLDCLLDIYQ 648          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Mouse
Match: Kcnq5 (potassium voltage-gated channel, subfamily Q, member 5 [Source:MGI Symbol;Acc:MGI:1924937])

HSP 1 Score: 364.385 bits (934), Expect = 3.561e-111
Identity = 180/316 (56.96%), Postives = 231/316 (73.10%), Query Frame = 3
Query:  540 RKSLLGKPI--VGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSF 1481
            R SLLGKP+        R++ +YR++Q+ +YN LERP+ W  V YH  VF  VF CL+LSV ST+ +    A   L  +E  ++  F  E+ +R+WSAGC  RY+ W+GRL FAR+PFC++D +V++ASI V++  +   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EKD   +  +YADALWWG ITL T+GYGD  P T LG+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D +S S+ATWKPHLK+ 
Sbjct:   87 RMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGWAFV-YHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKAL 401          

HSP 2 Score: 105.531 bits (262), Expect = 1.117e-22
Identity = 53/116 (45.69%), Postives = 79/116 (68.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDV--------KISEGYDSR--ISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +L+   K  IR IR ++F VA RKFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  +        KI+  +++    S+ +R+VK+E +V+S+E KLD  + +Y+
Sbjct:  505 DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQMTSDKKSREKITAEHETTDDPSMLARVVKVEKQVQSIESKLDCLLDIYQ 620          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Mouse
Match: Kcnq1 (potassium voltage-gated channel, subfamily Q, member 1 [Source:MGI Symbol;Acc:MGI:108083])

HSP 1 Score: 329.331 bits (843), Expect = 1.487e-103
Identity = 173/327 (52.91%), Postives = 232/327 (70.95%), Query Frame = 3
Query:  519 PNMHFVPRKSLLG--KPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDE-----RDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSD-PQSTSVATWKPHLK 1475
            P +   PR S+    +P++ R++         +Q ++YNFLERP  W    YH  VF  V  CL+ SVLST++     A   LF++E+ ++ +F TEY +RLWSAGCRS+Y    GRL FAR+P  ++DL+V++AS++VL +GS  Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD      R +  SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA+LIQ  WRCY+++ P S   ATWK +++
Sbjct:   18 PRVSLDPRVSIYSARRPLLARTH---------IQGRVYNFLERPTGWKCFVYHFTVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRIEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIYVR 332          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. UniProt/SwissProt
Match: sp|P56696|KCNQ4_HUMAN (Potassium voltage-gated channel subfamily KQT member 4 OS=Homo sapiens OX=9606 GN=KCNQ4 PE=1 SV=2)

HSP 1 Score: 412.92 bits (1060), Expect = 2.808e-131
Identity = 252/590 (42.71%), Postives = 340/590 (57.63%), Query Frame = 3
Query:  570 GRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSD-PQSTSVATWKPH---LKSFRASTI-------EKNTXXXXXXXXXXXXAVDRLAKFSRISTIKRRCEKLANTXXXXXXXXXXXXXXTIVLNSYNRNNGTXXXXXXXXXXXXXXXXXXXMYSTPAFSISRRNALAQSVEKYREDDQSTKKKFGILDDFFLNRYTSMASMTRDEILAE-DWDALLPKRELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGR--SDVKISEGYD---------SRISLASRIVKIETKVESMELKLDKFIQLY 2270
            G+  S    +YR+LQ+ +YN LERP+ W  V YH+ +F  VF+CLVLSVLST+ +    A E L  +E  ++  F  EY +R+WSAGC  RY+ W+GR  FAR+PFC++D +V +AS+ V+A G+   +FA SALR +RF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+F+SFL+YLAEKD      SYAD+LWWG ITL T+GYGD  P T LG+++A   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RRMPAA LIQ  WR YS+D  ++   ATW  +   L SFR   +        +N       +  +       +++  ++T    C +  +TS      S       I + S  R  G             +      M ++P+            V+K    +  T+ +  +     L   TS      +E+  E  +   L   ++    K  IR IR ++F VA RKFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + GR   D K  E  D           IS+  R+VK+E +V+S+E KLD  +  Y
Sbjct:   70 GQRSSAAHKRYRRLQNWVYNVLERPRGWAFV-YHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVAT----CHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGP----------SKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLR----LKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFY 640          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. UniProt/SwissProt
Match: sp|Q9JK45|KCNQ5_MOUSE (Potassium voltage-gated channel subfamily KQT member 5 OS=Mus musculus OX=10090 GN=Kcnq5 PE=1 SV=2)

HSP 1 Score: 365.155 bits (936), Expect = 1.586e-110
Identity = 181/323 (56.04%), Postives = 233/323 (72.14%), Query Frame = 3
Query:  540 RKSLLGKPI--VGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+        R++ +YR++Q+ +YN LERP+ W  V YH  VF  VF CL+LSV ST+ +    A   L  +E  ++  F  E+ +R+WSAGC  RY+ W+GRL FAR+PFC++D +V++ASI V++  +   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EKD   +  +YADALWWG ITL T+GYGD  P T LG+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D +S S+ATWKPHLK+    +  K
Sbjct:   87 RMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGWAFV-YHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTK 408          

HSP 2 Score: 105.531 bits (262), Expect = 7.551e-22
Identity = 53/116 (45.69%), Postives = 79/116 (68.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDV--------KISEGYDSR--ISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +L+   K  IR IR ++F VA RKFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  +        KI+  +++    S+ +R+VK+E +V+S+E KLD  + +Y+
Sbjct:  514 DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQMTSDKKSREKITAEHETTDDPSMLARVVKVEKQVQSIESKLDCLLDIYQ 629          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. UniProt/SwissProt
Match: sp|Q9NR82|KCNQ5_HUMAN (Potassium voltage-gated channel subfamily KQT member 5 OS=Homo sapiens OX=9606 GN=KCNQ5 PE=1 SV=3)

HSP 1 Score: 364.385 bits (934), Expect = 3.075e-110
Identity = 181/323 (56.04%), Postives = 233/323 (72.14%), Query Frame = 3
Query:  540 RKSLLGKPI--VGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+        R++ +YR++Q+ +YN LERP+ W A  YH  VF  VF CL+LSV ST+ +    A   L  +E  ++  F  E+ +R+WSAGC  RY+ W+GRL FAR+PFC++D +V++ASI V++  +   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EKD   +  +YADALWWG ITL T+GYGD  P T LG+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D +S S+ATWKPHLK+    +  K
Sbjct:   86 RMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGW-AFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTK 407          

HSP 2 Score: 107.842 bits (268), Expect = 1.811e-22
Identity = 53/116 (45.69%), Postives = 79/116 (68.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDV--------KISEGYDSR--ISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +L+   K  IR IR ++F VA RKFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  +        KI+  +++   +S+  R+VK+E +V+S+E KLD  + +Y+
Sbjct:  513 DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQ 628          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. UniProt/SwissProt
Match: sp|P70057|KCNQ1_XENLA (Potassium voltage-gated channel subfamily KQT member 1 OS=Xenopus laevis OX=8355 GN=kcnq1 PE=1 SV=2)

HSP 1 Score: 344.354 bits (882), Expect = 1.308e-105
Identity = 179/359 (49.86%), Postives = 245/359 (68.25%), Query Frame = 3
Query:  432 KNSKTSAQFDDDSEANPLN---KLYRSNSKELPNMHFVPRKSLLG--KPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERD-----KIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSD-PQSTSVATWKPHLK 1475
            ++  ++ Q  +D +AN      +   +     P ++  PR S+    +P++ R+          +Q ++YNFLERP  W    YH  VF  V  CL+ SVLST+    N A E LF++E+ ++ +F  EY +RLWSAGCRS+Y    GRL FAR+P  ++DL+V++AS+IVL +GS+ Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD  D     +  SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA+LIQ  WRCY+++ P S   ATWK +++
Sbjct:   41 QDGSSNGQRQEDRQANSFELKRETLVATDPPRPTINLDPRVSIYSGRRPLLSRT---------NIQGRVYNFLERPTGWKCFVYHFTVFLIVLICLIFSVLSTIQQYNNLATETLFWMEIVLVVFFGAEYVVRLWSAGCRSKYVGVWGRLRFARKPISVIDLIVVVASVIVLCVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAIDSSGEYQFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIYIR 387          

HSP 2 Score: 93.9745 bits (232), Expect = 2.278e-18
Identity = 60/157 (38.22%), Postives = 96/157 (61.15%), Query Frame = 3
Query: 1806 SVEKYREDDQSTKKKFGILDDFFLNRYTSMASMTRDEILAEDWDALL-PKRELSNTEKH---AIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKIS---EGYDSRI-SLASRIVKIETKVESMELKLD 2252
            SVE Y   + + +K FG LD      +   +S T D  L  + D LL P   +S  ++H   AI+ IR++++FVA +KF++A +PYD++D+IEQYS GH++++ RIK LQ RLD   G+  + +S   +  D  I ++ SR+ ++E KV  M+ KL+
Sbjct:  446 SVESY---ENTVRKPFGFLDPS-TGPFIRTSSFTDD--LDMEGDTLLTPITHISELKEHHRAAIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSLGKPSLFLSVSDKVKDKGINTIGSRLNRVEDKVTQMDHKLN 596          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. UniProt/SwissProt
Match: sp|Q9MYS6|KCNQ1_RABIT (Potassium voltage-gated channel subfamily KQT member 1 OS=Oryctolagus cuniculus OX=9986 GN=KCNQ1 PE=2 SV=3)

HSP 1 Score: 334.724 bits (857), Expect = 6.647e-102
Identity = 173/327 (52.91%), Postives = 233/327 (71.25%), Query Frame = 3
Query:  519 PNMHFVPRKSL--LGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDE-----RDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSD-PQSTSVATWKPHLK 1475
            P +   PR S+  + +P++ R++         +Q ++YNFLERP  W    YH  VF  V  CL+ SVLST++     A   LF++E+ ++ +F TEY +RLWSAGCRS+Y    GRL FAR+P  ++DL+V++AS++VL +GS  Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD      R +  SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA+LIQ  WRCY+++ P S   ATWK +++
Sbjct:   82 PPVSLDPRVSIYSVRRPLLARTH---------IQGRVYNFLERPTGWKCFAYHFTVFLIVLVCLIFSVLSTIEQYATLATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIYIR 396          

HSP 2 Score: 85.5001 bits (210), Expect = 8.806e-16
Identity = 53/152 (34.87%), Postives = 84/152 (55.26%), Query Frame = 3
Query: 1830 DQSTKKKFGILDDFFLNRYTSMASMTRDEILAEDWDA-----LLPKRELSNTEKH---AIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSD--VKISEGYDSRI--SLASRIVKIETKVESMELKL 2249
            D S +K   +L+        S     R    AED D      L P   +S   +H    ++ IR++++FVA +KF++A +PYD++D+IEQYS GH++++ RIK LQ RLD   G+    V ISE    R   S+ +R+ ++E KV  ++ +L
Sbjct:  461 DGSVRKSPALLE-------VSTPQFLRTNSFAEDLDLEGETLLAPITHVSQLREHHRATVKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFVPISEKSKDRGSNSIGARLNRVEDKVTQLDQRL 605          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. TrEMBL
Match: A0A1D1VIK0 (Uncharacterized protein OS=Ramazzottius varieornatus OX=947166 GN=RvY_12174-1 PE=3 SV=1)

HSP 1 Score: 520.39 bits (1339), Expect = 1.428e-166
Identity = 292/579 (50.43%), Postives = 377/579 (65.11%), Query Frame = 3
Query:  537 PRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKNTXXXXXXXXXXXXAVDRLAKFSRISTIKRRCEKLANTXXXXXXXXXXXXXXTI--VLNSYNRNNGTXXXXXXXXXXXXXXXXXXXMYSTPAFSISRRNALAQSVEKYREDDQSTKKKFGILDDFFLNRYTSMASMTRDEILAEDWDALLPKRELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQL 2267
            PR SL GK  V     R+DA+YRKLQ+K+YNFLERP+ + A+ YH++VF  VF C  L+VLSTV D  +   + LF++EL V+ WF  E+ LR+WS GCRSRYQ  +GRLLF ++PF ++D ++I ASI+VL LGS  Q+FAASALRGLRFFQILRM+RMDRRGG+WKLL SVVWAHRQEL TT YIGFL L+FSSFLIYL EKD  ++  ++ADALWWGVITL TVGYGD+VP +  GKLIAG CA+ GISFFALPA ILGSGFALKVQQ QR KHLIRRR PAA LIQC+WRCY++D +S SVATW+PHL+  R S     +S       SS S V R +   R   +       A+ +S     + + +  T    L S               D     ++    YS P       +    S E+ R    S            L +   +     D+      D ++ +REL++ ++ AIR IRK+++ VA RKF+EAL+PYD+KD+IEQYS+GHVD+LAR+K LQ R D L G+ + K  + YDS++ LA R+VKIE +V+ +E K+D  + L
Sbjct:  235 PRLSLHGK-AVSLRRHRRDARYRKLQAKVYNFLERPRGFRAITYHMLVFLLVFGCFCLTVLSTVPDFEDSTQQPLFWMELVVVVWFTVEFLLRMWSVGCRSRYQGVQGRLLFFKRPFTVIDTIIIFASIVVLGLGSHGQVFAASALRGLRFFQILRMVRMDRRGGTWKLLGSVVWAHRQELLTTFYIGFLGLIFSSFLIYLVEKDINERFTTFADALWWGVITLATVGYGDSVPISWKGKLIAGICAMMGISFFALPASILGSGFALKVQQQQRQKHLIRRRNPAALLIQCMWRCYAADERSCSVATWEPHLRGLRQSAAASVSSMPYKFHASSTSFVSRFSTIKRPKHVPNHVPPAAHGASGHGPHAPATAVVTASSALTSLKEGVTHTLKSASSGDLLRRVNSARKTYSAPP------DNAPTSGERARPSKGSITGVAQHHRRMALTQPEELRKALEDDDETSSVDGIV-QRELTDQQRRAIRAIRKMKYLVAKRKFREALKPYDVKDVIEQYSAGHVDLLARVKNLQQRCDQLLGKQNSKSVDSYDSKVCLALRVVKIERQVDDIEGKIDTVLDL 805          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. TrEMBL
Match: A0A267DKX4 (Ion_trans domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000995g3 PE=3 SV=1)

HSP 1 Score: 505.753 bits (1301), Expect = 4.463e-165
Identity = 247/386 (63.99%), Postives = 287/386 (74.35%), Query Frame = 3
Query:  528 HFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAX------------------------------XXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERD-KIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKNTXXXXXXXXXXXXAVDRLAKFSRISTIKR 1592
            H  PR SLLGKPI  +S +RQDA+YR+LQ+++YNFLERPK W ++ YH+IVFAS                                T    +           A E+LFY+E  +LFWFFTEYCLR+WSAGCRSRYQTWRGRLLFAR+PFC+VD +VI+ASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTT+YIGFL L+FSSF++YL EKDE+D +I +YADALWWGV+TLCTVGYGD  PKT  GK++A  C+IAGISFFALPAGILGSGFALKVQQHQR KHLIRRR+PAATLIQ LWRCY++DP STS+ATWKPH++  R+ +                      +KF R+STIKR
Sbjct:  209 HSKPRMSLLGKPINLKS-ARQDARYRRLQARVYNFLERPKTWQSITYHVIVFASVFICLVFSVLSTMSNCVRDAALKPSLTAPGQPTGAPGACSKFAFKYSEVASEILFYMETGMLFWFFTEYCLRMWSAGCRSRYQTWRGRLLFARRPFCIVDSIVIVASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTVYIGFLGLIFSSFVMYLIEKDEQDTQISNYADALWWGVVTLCTVGYGDVTPKTWSGKIVASFCSIAGISFFALPAGILGSGFALKVQQHQRQKHLIRRRVPAATLIQSLWRCYAADPSSTSMATWKPHMRPLRSPS----------------------SKFGRLSTIKR 571          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. TrEMBL
Match: A0A267E7M9 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000995g2 PE=3 SV=1)

HSP 1 Score: 507.294 bits (1305), Expect = 5.327e-162
Identity = 247/386 (63.99%), Postives = 287/386 (74.35%), Query Frame = 3
Query:  528 HFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAX------------------------------XXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERD-KIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKNTXXXXXXXXXXXXAVDRLAKFSRISTIKR 1592
            H  PR SLLGKPI  +S +RQDA+YR+LQ+++YNFLERPK W ++ YH+IVFAS                                T    +           A E+LFY+E  +LFWFFTEYCLR+WSAGCRSRYQTWRGRLLFAR+PFC+VD +VI+ASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTT+YIGFL L+FSSF++YL EKDE+D +I +YADALWWGV+TLCTVGYGD  PKT  GK++A  C+IAGISFFALPAGILGSGFALKVQQHQR KHLIRRR+PAATLIQ LWRCY++DP STS+ATWKPH++  R+ +                      +KF R+STIKR
Sbjct:  106 HSKPRMSLLGKPINLKS-ARQDARYRRLQARVYNFLERPKTWQSITYHVIVFASVFICLVFSVLSTMSNCVRDAALKPSLTAPGQPTGAPGACSKFAFKYSEVASEILFYMETGMLFWFFTEYCLRMWSAGCRSRYQTWRGRLLFARRPFCIVDSIVIVASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTVYIGFLGLIFSSFVMYLIEKDEQDTQISNYADALWWGVVTLCTVGYGDVTPKTWSGKIVASFCSIAGISFFALPAGILGSGFALKVQQHQRQKHLIRRRVPAATLIQSLWRCYAADPSSTSMATWKPHMRPLRSPS----------------------SKFGRLSTIKR 468          

HSP 2 Score: 135.961 bits (341), Expect = 8.366e-29
Identity = 62/106 (58.49%), Postives = 83/106 (78.30%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +L+   K AIR IR++++FVA +KF+EALRPYD+KD+IEQYS+GHVDMLARIK LQ RLD + GR   K  + Y+S++SLASRIVK+E  +E +E KL+  I +YK
Sbjct:  545 KLTEVHKTAIRVIRRIKYFVARKKFREALRPYDVKDVIEQYSAGHVDMLARIKVLQFRLDQILGRQGSKDKDAYESKVSLASRIVKVERSMEDVERKLELLIDMYK 650          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. TrEMBL
Match: A0A267FYJ7 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000995g4 PE=3 SV=1)

HSP 1 Score: 509.22 bits (1310), Expect = 1.733e-161
Identity = 247/386 (63.99%), Postives = 287/386 (74.35%), Query Frame = 3
Query:  528 HFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAX------------------------------XXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERD-KIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKNTXXXXXXXXXXXXAVDRLAKFSRISTIKR 1592
            H  PR SLLGKPI  +S +RQDA+YR+LQ+++YNFLERPK W ++ YH+IVFAS                                T    +           A E+LFY+E  +LFWFFTEYCLR+WSAGCRSRYQTWRGRLLFAR+PFC+VD +VI+ASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTT+YIGFL L+FSSF++YL EKDE+D +I +YADALWWGV+TLCTVGYGD  PKT  GK++A  C+IAGISFFALPAGILGSGFALKVQQHQR KHLIRRR+PAATLIQ LWRCY++DP STS+ATWKPH++  R+ +                      +KF R+STIKR
Sbjct:  210 HSKPRMSLLGKPINLKS-ARQDARYRRLQARVYNFLERPKTWQSITYHVIVFASVFICLVFSVLSTMSNCVRDAALKPSLTAPGQPTGAPGACSKFAFKYSEVASEILFYMETGMLFWFFTEYCLRMWSAGCRSRYQTWRGRLLFARRPFCIVDSIVIVASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTVYIGFLGLIFSSFVMYLIEKDEQDTQISNYADALWWGVVTLCTVGYGDVTPKTWSGKIVASFCSIAGISFFALPAGILGSGFALKVQQHQRQKHLIRRRVPAATLIQSLWRCYAADPSSTSMATWKPHMRPLRSPS----------------------SKFGRLSTIKR 572          

HSP 2 Score: 136.346 bits (342), Expect = 6.629e-29
Identity = 62/106 (58.49%), Postives = 83/106 (78.30%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +L+   K AIR IR++++FVA +KF+EALRPYD+KD+IEQYS+GHVDMLARIK LQ RLD + GR   K  + Y+S++SLASRIVK+E  +E +E KL+  I +YK
Sbjct:  649 KLTEVHKTAIRVIRRIKYFVARKKFREALRPYDVKDVIEQYSAGHVDMLARIKVLQFRLDQILGRQGSKDKDAYESKVSLASRIVKVERSMEDVERKLELLIDMYK 754          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. TrEMBL
Match: A0A4S2MFA0 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000425 PE=3 SV=1)

HSP 1 Score: 497.278 bits (1279), Expect = 2.862e-158
Identity = 250/357 (70.03%), Postives = 294/357 (82.35%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKNTXXXXXXXXXXXXAVDR--LAKFSRISTIKRRCEK 1604
            R SL GK I  R  SR + +YRKLQ+++YNFLERPK W +  YH +VFASV  CLVLSVLST+DD    A  +L Y+EL +LFWFFTEYC+RLWSAGCRSRYQTWRGR+ FA++PFCLVD VVI+AS+++LA+ +D  MFAASALRGLRFFQILRMIRMDRRGGS+KLLASVVWAHRQELFTT+YIGFL L+F+SFLIYL EK++ +KI+SYADALWWGV+TLCTVGYGDTVP+TA+GKLIA  CA+AGISFFALPAGILGSGFALKVQQHQR KHLIRRR+PAATLIQCLWRCY++DP S+S ATWK HL+  R  T   N+           S ++R   ++ SR ST+KRR EK
Sbjct:  113 RTSLHGKTITVR-ISRNETKYRKLQAQVYNFLERPKTWRSFTYHGLVFASVLGCLVLSVLSTIDDYAVVAMRLLLYMELVILFWFFTEYCIRLWSAGCRSRYQTWRGRIQFAKRPFCLVDFVVIVASVVILAVDNDGNMFAASALRGLRFFQILRMIRMDRRGGSFKLLASVVWAHRQELFTTVYIGFLCLIFTSFLIYLVEKNKNEKIQSYADALWWGVVTLCTVGYGDTVPRTAMGKLIAAFCALAGISFFALPAGILGSGFALKVQQHQRQKHLIRRRVPAATLIQCLWRCYAADPNSSSTATWKIHLRPVRKPTGLTNS----------ASVIERGGFSRLSRFSTLKRRPEK 458          

HSP 2 Score: 135.961 bits (341), Expect = 8.671e-29
Identity = 63/107 (58.88%), Postives = 84/107 (78.50%), Query Frame = 3
Query: 1953 RELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQLYK 2273
            R+L+  EK A+R IRK+RF VA RKF+EALRPYD+KD+IEQYS+GH+DML R+K LQ RLD + GR   K  + YDS  SLASRIVKIE KV+++++K+D+ + L +
Sbjct:  626 RQLTEQEKCAVRIIRKMRFLVARRKFREALRPYDVKDVIEQYSAGHLDMLTRVKQLQSRLDQILGRQGGKPEDVYDSHQSLASRIVKIEHKVDAIDVKIDRLVSLCR 732          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Cavefish
Match: kcnq5b (potassium voltage-gated channel subfamily KQT member 5-like [Source:NCBI gene;Acc:103029379])

HSP 1 Score: 371.318 bits (952), Expect = 5.655e-114
Identity = 184/322 (57.14%), Postives = 238/322 (73.91%), Query Frame = 3
Query:  540 RKSLLGKPIV-GRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP++ G    R++A+YR++Q+ +YN LERP++W  + YH  VF  VF CLVLSV ST+      A   LF +E  ++  F  EY +R+WSAGC  RY+ W+GRL FAR+PFC++D++V++AS+ V++ GS   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EK+   +  +YADALWWG ITL T+GYGD  PKT  G++++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D  S S+ATWKPHLK+    +  K
Sbjct:   62 RLSLLGKPLLYGAHGGRRNARYRRIQNCLYNLLERPRSWAFI-YHAFVFVLVFGCLVLSVFSTIPTHMEMASRALFILEFVMIVVFGLEYIVRIWSAGCCCRYRGWQGRLRFARKPFCIIDIIVLIASVAVVSAGSQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKEFSTYADALWWGTITLTTIGYGDKTPKTWTGRMLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAACLIQCVWRSYAADENSISIATWKPHLKALHTCSPTK 382          

HSP 2 Score: 107.457 bits (267), Expect = 2.573e-23
Identity = 59/130 (45.38%), Postives = 81/130 (62.31%), Query Frame = 3
Query: 1914 EILAEDWDALLPKRELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKI---------SEG-YDSRISLASRIVKIETKVESMELKLDKFIQLYK 2273
            EI AED   LLP        K  IR +R ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  V +         SEG     +S+  R+ K+E +V+S+E KLD  + +Y+
Sbjct:  484 EISAED---LLP------AVKTVIRAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQVPVDKKLREKLMSEGDLLEDVSMLGRVCKVERQVQSIESKLDSLLDIYR 604          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Cavefish
Match: kcnq5b (potassium voltage-gated channel subfamily KQT member 5-like [Source:NCBI gene;Acc:103029379])

HSP 1 Score: 370.163 bits (949), Expect = 1.158e-113
Identity = 183/315 (58.10%), Postives = 236/315 (74.92%), Query Frame = 3
Query:  540 RKSLLGKPIV-GRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSF 1481
            R SLLGKP++ G    R++A+YR++Q+ +YN LERP++W  + YH  VF  VF CLVLSV ST+      A   LF +E  ++  F  EY +R+WSAGC  RY+ W+GRL FAR+PFC++D++V++AS+ V++ GS   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EK+   +  +YADALWWG ITL T+GYGD  PKT  G++++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR Y++D  S S+ATWKPHLK+ 
Sbjct:   62 RLSLLGKPLLYGAHGGRRNARYRRIQNCLYNLLERPRSWAFI-YHAFVFVLVFGCLVLSVFSTIPTHMEMASRALFILEFVMIVVFGLEYIVRIWSAGCCCRYRGWQGRLRFARKPFCIIDIIVLIASVAVVSAGSQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKEFSTYADALWWGTITLTTIGYGDKTPKTWTGRMLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAACLIQCVWRSYAADENSISIATWKPHLKAL 375          

HSP 2 Score: 107.071 bits (266), Expect = 2.826e-23
Identity = 59/130 (45.38%), Postives = 81/130 (62.31%), Query Frame = 3
Query: 1914 EILAEDWDALLPKRELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKI---------SEG-YDSRISLASRIVKIETKVESMELKLDKFIQLYK 2273
            EI AED   LLP        K  IR +R ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  V +         SEG     +S+  R+ K+E +V+S+E KLD  + +Y+
Sbjct:  475 EISAED---LLP------AVKTVIRAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQVPVDKKLREKLMSEGDLLEDVSMLGRVCKVERQVQSIESKLDSLLDIYR 595          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Cavefish
Match: kcnq5a (potassium voltage-gated channel subfamily Q member 5 [Source:NCBI gene;Acc:103047497])

HSP 1 Score: 368.237 bits (944), Expect = 2.846e-113
Identity = 185/315 (58.73%), Postives = 236/315 (74.92%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYS-RQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSF 1481
            R SLLGKP+   + S R++A+YRKLQ+ +YN LERP+ W  V YH  VF  VF CLVLSV ST+    + +   L  +E  ++  F  EY +R+WSAGC  RY+ W+GRL FAR+PFC++D++V++ASI V++ GS   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EK+   +  +YADALWWG ITL T+GYGD  P+T  G+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA+LIQC+WR Y++D  S S+ATWKPHLK+ 
Sbjct:   60 RLSLLGKPLAYSAQSGRRNARYRKLQNYLYNVLERPRAWAFV-YHAFVFILVFGCLVLSVFSTIPAYMDLSNHCLLILEFVMIVVFGLEYIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLIASIAVVSAGSQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKQFATYADALWWGTITLTTIGYGDKTPQTWPGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAASLIQCVWRSYAADENSVSIATWKPHLKAL 373          

HSP 2 Score: 106.686 bits (265), Expect = 3.910e-23
Identity = 50/117 (42.74%), Postives = 75/117 (64.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKI-----------SEGYDSRISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +LS   K  IR +R ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  + +            E  +  +S+  R+ K+E +V+S+E KLD  + +Y+
Sbjct:  476 DLSAPLKTVIRAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIPMDRKMRDRILPEGESLEHDMSMLGRVCKVERQVQSIESKLDSLLDVYR 592          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Cavefish
Match: kcnq5a (potassium voltage-gated channel subfamily Q member 5 [Source:NCBI gene;Acc:103047497])

HSP 1 Score: 370.163 bits (949), Expect = 3.473e-113
Identity = 186/322 (57.76%), Postives = 238/322 (73.91%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYS-RQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+   + S R++A+YRKLQ+ +YN LERP+ W  V YH  VF  VF CLVLSV ST+    + +   L  +E  ++  F  EY +R+WSAGC  RY+ W+GRL FAR+PFC++D++V++ASI V++ GS   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EK+   +  +YADALWWG ITL T+GYGD  P+T  G+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA+LIQC+WR Y++D  S S+ATWKPHLK+    +  K
Sbjct:   60 RLSLLGKPLAYSAQSGRRNARYRKLQNYLYNVLERPRAWAFV-YHAFVFILVFGCLVLSVFSTIPAYMDLSNHCLLILEFVMIVVFGLEYIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLIASIAVVSAGSQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKQFATYADALWWGTITLTTIGYGDKTPQTWPGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAASLIQCVWRSYAADENSVSIATWKPHLKALHTCSPTK 380          

HSP 2 Score: 106.686 bits (265), Expect = 4.069e-23
Identity = 50/117 (42.74%), Postives = 75/117 (64.10%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKI-----------SEGYDSRISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +LS   K  IR +R ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  + +            E  +  +S+  R+ K+E +V+S+E KLD  + +Y+
Sbjct:  504 DLSAPLKTVIRAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIPMDRKMRDRILPEGESLEHDMSMLGRVCKVERQVQSIESKLDSLLDVYR 620          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Cavefish
Match: kcnq5a (potassium voltage-gated channel subfamily Q member 5 [Source:NCBI gene;Acc:103047497])

HSP 1 Score: 370.548 bits (950), Expect = 5.423e-113
Identity = 186/322 (57.76%), Postives = 238/322 (73.91%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYS-RQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+   + S R++A+YRKLQ+ +YN LERP+ W  V YH  VF  VF CLVLSV ST+    + +   L  +E  ++  F  EY +R+WSAGC  RY+ W+GRL FAR+PFC++D++V++ASI V++ GS   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EK+   +  +YADALWWG ITL T+GYGD  P+T  G+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA+LIQC+WR Y++D  S S+ATWKPHLK+    +  K
Sbjct:   60 RLSLLGKPLAYSAQSGRRNARYRKLQNYLYNVLERPRAWAFV-YHAFVFILVFGCLVLSVFSTIPAYMDLSNHCLLILEFVMIVVFGLEYIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLIASIAVVSAGSQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKQFATYADALWWGTITLTTIGYGDKTPQTWPGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAASLIQCVWRSYAADENSVSIATWKPHLKALHTCSPTK 380          

HSP 2 Score: 89.3521 bits (220), Expect = 1.079e-17
Identity = 53/155 (34.19%), Postives = 75/155 (48.39%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRS------------------------------------------DVKI-------SEGYDSRISLASRIVKIETKVESMELKLDKFIQLYK 2273
            +LS   K  IR +R ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ RLD + G                                            D K+        E  +  +S+  R+ K+E +V+S+E KLD  + +Y+
Sbjct:  504 DLSAPLKTVIRAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRLDTIVGPPQTLSSKSKTFSSPSLHLYYSQAKRKHSAPGVDQILGKGQIPMDRKMRDRILPEGESLEHDMSMLGRVCKVERQVQSIESKLDSLLDVYR 658          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Sea Lamprey
Match: kcnq1.1 (potassium voltage-gated channel, KQT-like subfamily, member 1.1 [Source:ZFIN;Acc:ZDB-GENE-061214-5])

HSP 1 Score: 309.686 bits (792), Expect = 7.731e-97
Identity = 147/251 (58.57%), Postives = 189/251 (75.30%), Query Frame = 3
Query:  771 ELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKD---ERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATW--KPHLKSFRASTIEKNT 1508
            E++++ +F  EY +RLWSAGCRS+Y    GR+ FA +P  ++DLVV++ASIIVL +GS+ Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAEKD   E+++  SYADALWWGV+T+ T+GYGD VP+T +GK IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AATLIQ LWRC+ ++    S ATW    H     A T E  T
Sbjct:    1 EIALVVFFGVEYLVRLWSAGCRSKYVGVMGRVRFAHKPISIIDLVVVVASIIVLCVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDEAREKNEFASYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQSLWRCHLAESDHHSTATWMIDAHFNGISAKTAEHVT 251          

HSP 2 Score: 87.4261 bits (215), Expect = 2.421e-18
Identity = 45/95 (47.37%), Postives = 71/95 (74.74%), Query Frame = 3
Query: 1959 LSNTEKHAIRFIRKVRFFVASRKFKE-ALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISE-GYD-SRISLASRIVKIETKVES 2234
            L+ + K AIR IR++++FVA  KF++ A +PYD++D+IEQYS GHV+M+ RIK LQ RLD+  G+ ++ +SE G D S+ ++ +R+ ++E KV S
Sbjct:  351 LTESHKIAIRVIRRMQYFVARSKFQQQAKKPYDVRDVIEQYSQGHVNMMVRIKELQRRLDHSLGKPNMFLSEKGKDRSKYTIGARLDRVEEKVHS 445          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001128.1 (pep scaffold:Pmarinus_7.0:GL481044:147302:155278:-1 gene:ENSPMAG00000001003.1 transcript:ENSPMAT00000001128.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 294.278 bits (752), Expect = 1.818e-93
Identity = 143/226 (63.27%), Postives = 174/226 (76.99%), Query Frame = 3
Query:  792 FFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDK-IKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTS-VATWK 1463
            F  EY  R+W+AGC  RY+ WRGRL F+R+PFC++D++V++AS+ VLA G+   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVLVFSSFL+YLAEKDE  K   +YADALWWG ITL T+GYGD  P T +G+L+A   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQ  WR +S+D      +ATW+
Sbjct:   26 FGIEYIARIWAAGCCCRYRGWRGRLKFSRKPFCVIDIIVLIASLAVLAAGTQGNVFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLVFSSFLVYLAEKDENQKEFGTYADALWWGTITLTTIGYGDKCPVTWVGRLMAASFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRSPAAGLIQAAWRLHSTDASRPHLIATWR 251          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009923.1 (pep scaffold:Pmarinus_7.0:GL476399:1077789:1091635:1 gene:ENSPMAG00000008976.1 transcript:ENSPMAT00000009923.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 236.113 bits (601), Expect = 1.178e-72
Identity = 112/174 (64.37%), Postives = 140/174 (80.46%), Query Frame = 3
Query:  792 FFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDE-RDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPA 1310
            F  EY LR+W+AGC  RY+ W+GRL FAR+PFC++D +V++AS+ V+A G+   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFL LVFSSFL+YLAEKD+ +D+  +YADALWWG ITL T+GYGD  PKT LG+++A   A+ GISFFALPA
Sbjct:   24 FGLEYFLRIWAAGCCCRYRGWQGRLRFARKPFCIIDSIVLVASLAVIAAGTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLALVFSSFLVYLAEKDDNKDQFATYADALWWGTITLTTIGYGDKTPKTWLGRMLAAGFALLGISFFALPA 197          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009926.1 (pep scaffold:Pmarinus_7.0:GL476399:1078231:1091635:1 gene:ENSPMAG00000008976.1 transcript:ENSPMAT00000009926.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 227.254 bits (578), Expect = 2.207e-69
Identity = 112/183 (61.20%), Postives = 140/183 (76.50%), Query Frame = 3
Query:  792 FFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDE-RDKIKSYADALWWGV---------ITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPA 1310
            F  EY LR+W+AGC  RY+ W+GRL FAR+PFC++D +V++AS+ V+A G+   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFL LVFSSFL+YLAEKD+ +D+  +YADALWWG          ITL T+GYGD  PKT LG+++A   A+ GISFFALPA
Sbjct:   13 FGLEYFLRIWAAGCCCRYRGWQGRLRFARKPFCIIDSIVLVASLAVIAAGTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLALVFSSFLVYLAEKDDNKDQFATYADALWWGTGWGLLVLADITLTTIGYGDKTPKTWLGRMLAAGFALLGISFFALPA 195          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Sea Lamprey
Match: kcnq4 (potassium voltage-gated channel, KQT-like subfamily, member 4 [Source:ZFIN;Acc:ZDB-GENE-120215-132])

HSP 1 Score: 125.176 bits (313), Expect = 5.831e-34
Identity = 54/91 (59.34%), Postives = 72/91 (79.12%), Query Frame = 3
Query:  792 FFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWA 1064
            F  EY  R+W+AGC  RY+ WRGR  FAR+PFC++D++V++AS+ V+  G+   +FA SALR LRF QILRM+RMDRRGG+W+LL SVV+A
Sbjct:   35 FGLEYFARIWAAGCCCRYRGWRGRCRFARKPFCVIDIIVLIASLAVIIAGTQGNVFATSALRSLRFLQILRMVRMDRRGGTWRLLGSVVYA 125          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Nematostella
Match: EDO42799 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A4])

HSP 1 Score: 255.373 bits (651), Expect = 2.677e-78
Identity = 136/269 (50.56%), Postives = 188/269 (69.89%), Query Frame = 3
Query:  600 YRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQ 1406
            YR++Q   YNFLERP+   A+ YH+ +   V   L+L+ LSTV+         +F VE+ ++  F  EY LRLWSAGCRS Y   RGRL FA++ + ++D++VI +SI  LAL ++    ++  +R +RF  +LR++R DR+G +WKLLASV++ HR+EL TT+Y+GF+ L+F+SF++Y+ EKDE  K  S+ ++ WWG++TL T+GYGD  P T  G+L A   A+ GISFFALPAGILGSGFALKV Q QR KH  RRR PAA L+Q
Sbjct:    1 YRRIQLYCYNFLERPRGL-AIVYHVALCILVIVSLILTALSTVNIYEALLDTPIFIVEIVLVTVFIVEYGLRLWSAGCRSTYVGLRGRLNFAKKTYAILDVLVIFSSIAGLALSTNG---SSITVRLVRFLPLLRVLRFDRQGSTWKLLASVIYIHRKELLTTLYLGFISLIFASFVLYMVEKDENVKFDSWPNSFWWGIVTLTTIGYGDKTPITWYGRLCASIFAVCGISFFALPAGILGSGFALKVTQQQRQKHFHRRRRPAAILLQ 265          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Nematostella
Match: SHAKR9 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI03])

HSP 1 Score: 121.324 bits (303), Expect = 1.812e-29
Identity = 64/198 (32.32%), Postives = 110/198 (55.56%), Query Frame = 3
Query:  741 NYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALG-SDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGF 1331
            +Y  +  F +E   + WF  E+ +R+W++ C     TW    LF +  F ++D+  I+   I LAL  S   + + + +R LR F+++R+ ++ R   + KLL   +++  ++L + ++   + ++  S +IY    D++D I S   A WW VIT+ +VGYGD VP T  GKL+   CA++G+  F LP  +L S F
Sbjct:  195 HYFTDYWFVIEAYCVAWFTVEFVVRMWASPC-----TW----LFVKSWFGVLDVAAIVPFYITLALKESTYGVRSFAVIRALRLFRVIRIFKLSRYSDALKLLVKTLYSSSEQLRSLLFCFLVAIILFSSIIYYV--DDKDNIPSIPHAFWWSVITMTSVGYGDVVPSTIAGKLVGSLCAMSGLILFCLPTPVLVSNF 381          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Nematostella
Match: EDO48059 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJY3])

HSP 1 Score: 110.153 bits (274), Expect = 1.293e-25
Identity = 78/265 (29.43%), Postives = 125/265 (47.17%), Query Frame = 3
Query:  597 QYRKLQSKIYNFLERPKNWNAVGYHIIV---FAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDK-IKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFAL-------KVQQHQR 1358
            ++ + + K++ FL+ P +  A    I++      V                ++  ++L++++ S   WF  E+ LRL    C S  +       FA+ P   VDL  IL     L    D Q+     +R LR F+I  +        S+++L   + + + ELF       + ++  S +IY AEKD  DK  +S  ++ WW +IT+ TVGYGD  P T LGK+I   CAI G+   ALP  ++GS F+        +VQQ +R
Sbjct:  168 RWNRFRPKVWAFLDDPHSSKASWVFIMISCLMILVSVTQFCLGTVPSLREDSFTMKVLYWLDFSTSIWFTVEFVLRL--VFCPSTKE-------FAKNPMNWVDLTAILPFYFRLFKLQD-QISWLVVMRTLRIFRIFSL------SLSFQILFRSLISSKNELFLVFVSVMVPIILFSSMIYFAEKDANDKNFQSIPESFWWAIITVTTVGYGDVCPVTKLGKVIGAVCAICGVVIVALPVSVIGSNFSYYYIQARTRVQQPRR 416          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Nematostella
Match: SHAK3 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK45])

HSP 1 Score: 109.383 bits (272), Expect = 1.395e-25
Identity = 64/197 (32.49%), Postives = 104/197 (52.79%), Query Frame = 3
Query:  768 VELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFL-VLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQ 1355
            +E+  + WF  EY +RL S+           +LLF R    ++DL+ IL   I L +  D ++ + + LR +R  ++ R+ ++ R     ++L   + A  +EL   I+   + V++FSS + Y  E++   K  S  DA WW V+T+ TVGYGD  P T  GKL+   CAI+G+   ALP  ++ S F    ++ Q
Sbjct:  193 LEILCIAWFTLEYVVRLLSSP---------QKLLFVRSFLNVIDLMAILPYYITLPM-KDLRITSLAVLRVIRLVRVFRIFKLSRHSRGLQVLGHTLRASSRELAMLIFFLLISVVLFSSAVYYAEEEEAASKFSSIPDAFWWAVVTMTTVGYGDMYPVTPWGKLVGSICAISGVLTIALPVPVIVSNFNYFYKREQ 379          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Nematostella
Match: SHAKR12 (Potassium channel; Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI05])

HSP 1 Score: 105.145 bits (261), Expect = 7.834e-24
Identity = 56/193 (29.02%), Postives = 100/193 (51.81%), Query Frame = 3
Query:  762 FYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDR-QMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFL-VLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAG-ISFFALPAGILGSGF 1331
            F ++  ++ WF +EY  RL SA           +L F      L+DL+ I+   I L L +D+      + LR  R  +++R++++ R   + ++L   + + + +L   +++  + +++FSS + YL  ++   +  S   A WW +IT+ TVGYGDT P+T  G+L+  CCA+ G I    LP  +    F
Sbjct:  207 FVIDTCIITWFTSEYIARLISAP---------HKLKFVFSTLALIDLIAIIPYFISLGLDADQTHAITFTVLRIFRLLRVIRLLKLTRYVAALRILGYTIQSCQDQLTALMFLLLISIILFSSLMYYLENEENPTEFYSIPAAFWWCIITMTTVGYGDTCPRTPFGRLVGACCAVFGVIVMVCLPTPVFILHF 390          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Medaka
Match: kcnq5a (potassium voltage-gated channel subfamily KQT member 5 [Source:NCBI gene;Acc:101161745])

HSP 1 Score: 364.385 bits (934), Expect = 1.715e-112
Identity = 183/322 (56.83%), Postives = 235/322 (72.98%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYS-RQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+   + S R++A+YR+LQ+ +YN LERP+ W  V YH  VF  VF CLVLSV ST+     ++   L  +E  ++  F  EY  R+WSAGC  RY+ W+GRL FAR+PFC++D++V++ S+ V++ GS   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EK+      +YADALWWG ITL T+GYGD  P+T  G+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA+LIQC+WR Y++D  S S+ATWKPHLK+    +  K
Sbjct:   68 RLSLLGKPLTYSAQSGRRNARYRRLQNCLYNVLERPREWAFV-YHAFVFILVFGCLVLSVFSTIPAHQEFSSHCLLILEFVMIVVFGLEYIFRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLITSVAVVSAGSQGNVFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKDFDTYADALWWGTITLTTIGYGDKTPQTWTGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAASLIQCVWRSYAADENSVSIATWKPHLKALHTCSPAK 388          

HSP 2 Score: 96.2857 bits (238), Expect = 5.654e-20
Identity = 44/103 (42.72%), Postives = 67/103 (65.05%), Query Frame = 3
Query: 1995 RKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRI----------SLASRIVKIETKVESMELKLDKFIQLYK 2273
            R ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  + + +    ++          S+  R+ K+E +V S+E KLD  + +Y+
Sbjct:  397 RIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIPVEKKPRDKLHPDGDSLEGMSMLGRVCKVERQVSSIESKLDSLLDIYR 499          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Medaka
Match: kcnq5a (potassium voltage-gated channel subfamily KQT member 5 [Source:NCBI gene;Acc:101161745])

HSP 1 Score: 365.155 bits (936), Expect = 1.130e-111
Identity = 183/322 (56.83%), Postives = 235/322 (72.98%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYS-RQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+   + S R++A+YR+LQ+ +YN LERP+ W  V YH  VF  VF CLVLSV ST+     ++   L  +E  ++  F  EY  R+WSAGC  RY+ W+GRL FAR+PFC++D++V++ S+ V++ GS   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EK+      +YADALWWG ITL T+GYGD  P+T  G+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA+LIQC+WR Y++D  S S+ATWKPHLK+    +  K
Sbjct:   68 RLSLLGKPLTYSAQSGRRNARYRRLQNCLYNVLERPREWAFV-YHAFVFILVFGCLVLSVFSTIPAHQEFSSHCLLILEFVMIVVFGLEYIFRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLITSVAVVSAGSQGNVFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKDFDTYADALWWGTITLTTIGYGDKTPQTWTGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAASLIQCVWRSYAADENSVSIATWKPHLKALHTCSPAK 388          

HSP 2 Score: 103.99 bits (258), Expect = 2.981e-22
Identity = 49/116 (42.24%), Postives = 74/116 (63.79%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRI----------SLASRIVKIETKVESMELKLDKFIQLYK 2273
            +LS   K  IR +R ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  + + +    ++          S+  R+ K+E +V S+E KLD  + +Y+
Sbjct:  500 DLSAPLKAVIRAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIPVEKKPRDKLHPDGDSLEGMSMLGRVCKVERQVSSIESKLDSLLDIYR 615          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Medaka
Match: kcnq5a (potassium voltage-gated channel subfamily KQT member 5 [Source:NCBI gene;Acc:101161745])

HSP 1 Score: 364.77 bits (935), Expect = 1.470e-111
Identity = 182/315 (57.78%), Postives = 233/315 (73.97%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYS-RQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSF 1481
            R SLLGKP+   + S R++A+YR+LQ+ +YN LERP+ W  V YH  VF  VF CLVLSV ST+     ++   L  +E  ++  F  EY  R+WSAGC  RY+ W+GRL FAR+PFC++D++V++ S+ V++ GS   +FA SALR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+FSSFL+YL EK+      +YADALWWG ITL T+GYGD  P+T  G+L++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA+LIQC+WR Y++D  S S+ATWKPHLK+ 
Sbjct:   68 RLSLLGKPLTYSAQSGRRNARYRRLQNCLYNVLERPREWAFV-YHAFVFILVFGCLVLSVFSTIPAHQEFSSHCLLILEFVMIVVFGLEYIFRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLITSVAVVSAGSQGNVFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKDFDTYADALWWGTITLTTIGYGDKTPQTWTGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAASLIQCVWRSYAADENSVSIATWKPHLKAL 381          

HSP 2 Score: 103.99 bits (258), Expect = 2.642e-22
Identity = 49/116 (42.24%), Postives = 74/116 (63.79%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRI----------SLASRIVKIETKVESMELKLDKFIQLYK 2273
            +LS   K  IR +R ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  + + +    ++          S+  R+ K+E +V S+E KLD  + +Y+
Sbjct:  491 DLSAPLKAVIRAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIPVEKKPRDKLHPDGDSLEGMSMLGRVCKVERQVSSIESKLDSLLDIYR 606          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Medaka
Match: kcnq5b (potassium voltage-gated channel subfamily KQT member 5-like [Source:NCBI gene;Acc:101171724])

HSP 1 Score: 360.533 bits (924), Expect = 4.143e-109
Identity = 181/322 (56.21%), Postives = 234/322 (72.67%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYS-RQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+V  + S R++ +YR+LQ+ +YN LERP+ W  + YH  VF  VF+CLVLSV ST+     ++   L  +E  ++  F  EY +R+WSAGC  RY+ W+GRL FAR+PFC++D++V++AS+ V++ GS   +FA S LR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+F+SFL+YL E        +YADALWWG ITL T+GYGD  PKT  G++++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR YS+D  S S+ATWKPHLK+    +  K
Sbjct:   64 RLSLLGKPLVYSAQSGRRNVRYRRLQNYLYNVLERPRAWAFI-YHAFVFILVFSCLVLSVFSTIPAHQEFSSYCLLILEFVMIVVFGFEYIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLIASVAVVSAGSQGNIFATSVLRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFASFLVYLVENKFNKDFATYADALWWGTITLTTIGYGDKTPKTWTGRMLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAYLIQCVWRSYSADENSVSIATWKPHLKAMHTCSPTK 384          

HSP 2 Score: 103.605 bits (257), Expect = 4.284e-22
Identity = 48/116 (41.38%), Postives = 75/116 (64.66%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRI----------SLASRIVKIETKVESMELKLDKFIQLYK 2273
            +L  + K  IR +R ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ R+D + G+  + + +    ++          S+  R+ K+E +V+S+E KLD  + +Y+
Sbjct:  510 DLLPSVKAVIRAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIPLDKKIRDKLLSDGDLLEDMSMLGRVCKVERQVQSIESKLDSLLDIYR 625          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Medaka
Match: kcnq5b (potassium voltage-gated channel subfamily KQT member 5-like [Source:NCBI gene;Acc:101171724])

HSP 1 Score: 360.533 bits (924), Expect = 4.697e-109
Identity = 181/322 (56.21%), Postives = 234/322 (72.67%), Query Frame = 3
Query:  540 RKSLLGKPIVGRSYS-RQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEK 1502
            R SLLGKP+V  + S R++ +YR+LQ+ +YN LERP+ W  + YH  VF  VF+CLVLSV ST+     ++   L  +E  ++  F  EY +R+WSAGC  RY+ W+GRL FAR+PFC++D++V++AS+ V++ GS   +FA S LR LRF QILRM+RMDRRGG+WKLL SVV+AH +EL T  YIGFLVL+F+SFL+YL E        +YADALWWG ITL T+GYGD  PKT  G++++   A+ GISFFALPAGILGSGFALKVQ+  R KH  +RR PAA LIQC+WR YS+D  S S+ATWKPHLK+    +  K
Sbjct:   64 RLSLLGKPLVYSAQSGRRNVRYRRLQNYLYNVLERPRAWAFI-YHAFVFILVFSCLVLSVFSTIPAHQEFSSYCLLILEFVMIVVFGFEYIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLIASVAVVSAGSQGNIFATSVLRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFASFLVYLVENKFNKDFATYADALWWGTITLTTIGYGDKTPKTWTGRMLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAYLIQCVWRSYSADENSVSIATWKPHLKAMHTCSPTK 384          

HSP 2 Score: 86.6557 bits (213), Expect = 6.736e-17
Identity = 49/152 (32.24%), Postives = 75/152 (49.34%), Query Frame = 3
Query: 1956 ELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRL------------------------------------DNLFGRSDVKISEGYDSRI----------SLASRIVKIETKVESMELKLDKFIQLYK 2273
            +L  + K  IR +R ++F VA +KFKE LRPYD+KD+IEQYS+GH+DML RIK LQ RL                                    D + G+  + + +    ++          S+  R+ K+E +V+S+E KLD  + +Y+
Sbjct:  491 DLLPSVKAVIRAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRLDLIVGPKVLSSRAKTFSSPSLHLYYSQGRKNSTQGVDQILGKGQIPLDKKIRDKLLSDGDLLEDMSMLGRVCKVERQVQSIESKLDSLLDIYR 642          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Planmine SMEST
Match: SMESG000048964.1 (SMESG000048964.1)

HSP 1 Score: 1127.08 bits (2914), Expect = 0.000e+0
Identity = 589/632 (93.20%), Postives = 593/632 (93.83%), Query Frame = 3
Query:  108 MDIFRHQEVHPSENSVCIDVDTLHISEENNNYANSGFDTNLSGFSPTENMNYKCRSNSLSKANDSRHEASSKIREKRQRYAKNSPRHQKTISGLINIAEDKEHIQLESKNSKTSAQFDDDSEANPLNKLYRSNSKELPNMHFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKNTXXXXXXXXXXXXAVDRLAKFSRISTIKRRCEKLANTXXXXXXXXXXXXXXTIVLNSYNRNNGTXXXXXXXXXXXXXXXXXXXMYSTPAFSISRRNALAQSVEKYREDDQSTKKKFGILDDFFLNRYTSMASMTRDEILAEDWDALLPKRELSNTEKHAIRFIRKV 2003
            MDIFRHQEVHPSENSVCIDVDTLHISEENNNYANSGFDTNLSGFSPTENMNYKCRSNSLSKANDSRHEASSKIREKRQRYAKNSPRHQKTISGLINIAEDKEHIQLESKNSKTSAQFDDDSEANPLNKLYRSNSKELPNMHFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFASVFTCLVLSVLSTVDDVGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKNTS             DRLAKFSRISTIKRRCEKLANTSSSGQS          + +S++ N             DDEDSNNFNMYSTPAFSISRRNALAQSVEKYREDDQSTKKKFGILDDFFLNRYTSMASMTRDEILAEDWDALLPKRELSNTEKHAIRFIRK 
Sbjct:    1 MDIFRHQEVHPSENSVCIDVDTLHISEENNNYANSGFDTNLSGFSPTENMNYKCRSNSLSKANDSRHEASSKIREKRQRYAKNSPRHQKTISGLINIAEDKEHIQLESKNSKTSAQFDDDSEANPLNKLYRSNSKELPNMHFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFASVFTCLVLSVLSTVDDVGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKNTS-------------DRLAKFSRISTIKRRCEKLANTSSSGQS----------LSHSFSSNEDP----------DDEDSNNFNMYSTPAFSISRRNALAQSVEKYREDDQSTKKKFGILDDFFLNRYTSMASMTRDEILAEDWDALLPKRELSNTEKHAIRFIRKA 599          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Planmine SMEST
Match: SMESG000046611.1 (SMESG000046611.1)

HSP 1 Score: 593.578 bits (1529), Expect = 0.000e+0
Identity = 333/618 (53.88%), Postives = 419/618 (67.80%), Query Frame = 3
Query:  459 DDDSEANPLNKLYRSNSKE--LPNMHFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKNTXXXXXXXXXXXXAVDRLAKFSRISTIKRRCEKLANTXXXXXXXXXXXXXXTIVLNSYNRNNGTXXXXXXXXXXXXXXXXXXXMYSTPAFS-ISRRNALAQSVEKYREDDQSTKKKFGILDDFFLNRYTSMASMTRDEILAEDWDALLPKRELSNTE-----------KHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQLY 2270
            ++D+  N   + YR   K       H   R SL GK +  R+ +R DA+YR+LQ+KIYNFLERPK ++++ YHI++FASVF CL+LSVLST+    + AGE L Y EL +LFWFFTEYCLR+WSAGCRSRYQ+WRGR+ FA++PFCLVD+VVILAS++VL +GSDRQ  AASA RGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTT+YIGFL L+FSSFLIYL EKD+  KI +YADALWWGVITLCTVGYGD VP+T +GK+IA  CA+AGISFFALPAGILGSGFALKVQQHQR KHLIRRR+PAATLIQCLWRCY++DP STS ATWK H+K  R+                     DRL +F R S+IKRR EK +                  +L+S+  N+       ++    ++ + +      PA + +     L  S+   R    S KK+F  L     +      S       + ++   + K    N E           K+ IR +RK++FFVA +KF+EALRPYD+KD++EQYS+GHVDMLARIK LQ RLD + G+   K ++ Y+++ISL +RI+KIE +VES+E KLD  I +Y
Sbjct:   31 ENDNMINSQRREYRCAEKSSYFKERHSRHRTSLHGKALNFRA-NRNDARYRRLQAKIYNFLERPKTYSSIIYHILIFASVFMCLMLSVLSTIAKYDHIAGEALLYTELVMLFWFFTEYCLRMWSAGCRSRYQSWRGRIQFAKRPFCLVDVVVILASVVVLVIGSDRQKIAASAFRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTVYIGFLGLIFSSFLIYLVEKDKNQKINTYADALWWGVITLCTVGYGDIVPETWIGKIIAAFCAVAGISFFALPAGILGSGFALKVQQHQRQKHLIRRRVPAATLIQCLWRCYAADPNSTSGATWKIHMKPLRSPP-----------------NSDRLTRFGRFSSIKRRREKGS------------------ILHSHPSNSSLYRRNAIETSVPNQVTPSCEENEFPASNDVYNEEFLENSINSSR----SMKKRFRALAQSMKSHMNINPSSIEASRRSSNFVMAIEKESAVNDEIQFITQLTEADKNVIRAVRKIKFFVARKKFREALRPYDVKDVMEQYSAGHVDMLARIKNLQSRLDLIVGQHGSKDNQNYETKISLTTRIIKIEKQVESIETKLDLLIDMY 608          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Planmine SMEST
Match: SMESG000046611.1 (SMESG000046611.1)

HSP 1 Score: 584.334 bits (1505), Expect = 0.000e+0
Identity = 328/618 (53.07%), Postives = 416/618 (67.31%), Query Frame = 3
Query:  459 DDDSEANPLNKLYRSNSKE--LPNMHFVPRKSLLGKPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRASTIEKNTXXXXXXXXXXXXAVDRLAKFSRISTIKRRCEKLANTXXXXXXXXXXXXXXTIVLNSYNRNNGTXXXXXXXXXXXXXXXXXXXMYSTPAFS-ISRRNALAQSVEKYREDDQSTKKKFGILDDFFLNRYTSMASMTRDEILAEDWDALLPKRELSNTE-----------KHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRIVKIETKVESMELKLDKFIQLY 2270
            ++D+  N   + YR   K       H   R SL GK +  R+ +R DA+YR+LQ+KIYNFLERPK ++++ YHI++FASVF CL+LSVLST+    + AGE L Y EL +LFWFFTEYCLR+WSAGCRSRYQ+WRGR+ FA++PFCLVD+VVILAS++VL +GSDRQ  AASA RGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTT+YIGFL L+FSSFLIYL EKD+  KI +YADALWWGV+TLCTVGYGD VP + LGK+IAGC  ++ ISF+ALP GILGSGFALKVQQHQR KHLIRRR+PAATLIQCLWRCY++DP STS ATWK H+K  R+                     DRL +F R S+IKRR EK +                  +L+S+  N+       ++    ++ + +      PA + +     L  S+   R    S KK+F  L     +      S       + ++   + K    N E           K+ IR +RK++FFVA +KF+EALRPYD+KD++EQYS+GHVDMLARIK LQ RLD + G+   K ++ Y+++ISL +RI+KIE +VES+E KLD  I +Y
Sbjct:   31 ENDNMINSQRREYRCAEKSSYFKERHSRHRTSLHGKALNFRA-NRNDARYRRLQAKIYNFLERPKTYSSIIYHILIFASVFMCLMLSVLSTIAKYDHIAGEALLYTELVMLFWFFTEYCLRMWSAGCRSRYQSWRGRIQFAKRPFCLVDVVVILASVVVLVIGSDRQKIAASAFRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTVYIGFLGLIFSSFLIYLVEKDKNQKINTYADALWWGVVTLCTVGYGDAVPTSWLGKIIAGCSCLSIISFYALPPGILGSGFALKVQQHQRQKHLIRRRVPAATLIQCLWRCYAADPNSTSGATWKIHMKPLRSPP-----------------NSDRLTRFGRFSSIKRRREKGS------------------ILHSHPSNSSLYRRNAIETSVPNQVTPSCEENEFPASNDVYNEEFLENSINSSR----SMKKRFRALAQSMKSHMNINPSSIEASRRSSNFVMAIEKESAVNDEIQFITQLTEADKNVIRAVRKIKFFVARKKFREALRPYDVKDVMEQYSAGHVDMLARIKNLQSRLDLIVGQHGSKDNQNYETKISLTTRIIKIEKQVESIETKLDLLIDMY 608          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Planmine SMEST
Match: SMESG000022978.1 (SMESG000022978.1)

HSP 1 Score: 343.584 bits (880), Expect = 7.768e-104
Identity = 175/298 (58.72%), Postives = 216/298 (72.48%), Query Frame = 3
Query:  612 QSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEK-----------DERDKI---KSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWK 1463
            Q+ IYNFLE P  W    YH  VF  V  CL+LSVLST+D     A   LF++E+ ++ +F  EY +RLWSAGCRS+Y  +RGR+ FAR+P  ++DLVV+LAS +VL  GS  Q+FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL L+FSS+ +YLAE            DE  +I   KSYADALWWGVIT+ T+GYGD VPKT +GK+IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AATLIQCLWRCY+  P S   +TWK
Sbjct:   87 QTIIYNFLEFPTGWKCFLYHFAVFLLVLICLILSVLSTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWK 384          

HSP 2 Score: 93.5893 bits (231), Expect = 3.357e-19
Identity = 61/198 (30.81%), Postives = 108/198 (54.55%), Query Frame = 3
Query: 1938 ALLPKRELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGY--DSRISLASRIVKIETKVESMELKLDKFIQLYKXXXXXXXXXXXXXVPNSTHFRQ---FTPEIVPHPSSPLIYHR---------------PTCVGFVENFNTSSETRQQQTDHKSQT 2471
            AL    EL+   K AIR IR+++FF+A R+F++A +PYD++D+IEQYS GH++M+ RIK LQ R+D   G+  ++  +     +R+++ SR+ ++E++   M+ KLD+ + L  +    + N+       S+HFR     T  +    + P++Y +               PTC G +   ++ S ++  Q   K +T
Sbjct:  540 ALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIASCSINNQ-----RSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQTLHPTCSGKLLRSSSFSTSQIPQISEKEKT 732          
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Planmine SMEST
Match: SMESG000040474.1 (SMESG000040474.1)

HSP 1 Score: 331.643 bits (849), Expect = 1.861e-103
Identity = 164/296 (55.41%), Postives = 217/296 (73.31%), Query Frame = 3
Query:  609 LQSKIYNFLERPKNWNAVGYHIIVFAXXXXXXXXXXXXXXXXXGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWRGRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAE--KDERDKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALPAGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVATWKPHLKSFRAS 1490
             ++KIYNFLERP  W    YH  VF  V  CL+ SV+ST+D     +  +L+ +E  ++F+F  EY +RLWS+GCRS+Y  + GRL F R+P  L+DL+V++AS IVL  GS  ++FA SA+RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFL LVFSS+ +YL+E   +  ++  SYADALWWGV+T+ T+GYGD VPKT +GK+IA C ++  ISFFALPAGILGSGFALKVQQ QR KH  R+   AA LIQCLWR ++S  +  SVATW+ + +   +S
Sbjct:   50 FKTKIYNFLERPTGWKCFLYHFTVFIMVLVCLIFSVISTIDVYYEMSSYLLYIMETILVFFFGAEYIIRLWSSGCRSKYLGFSGRLRFMRKPISLIDLIVVVASFIVLLFGSKGKVFATSAIRGIRFMQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLVFSSYFVYLSENSNEPSNEFMSYADALWWGVVTVTTIGYGDKVPKTWIGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAANLIQCLWRLHASSVKFNSVATWRIYTQPVESS 345          

HSP 2 Score: 86.6557 bits (213), Expect = 2.384e-17
Identity = 42/98 (42.86%), Postives = 70/98 (71.43%), Query Frame = 3
Query: 1959 LSNTEKHAIRFIRKVRFFVASRKFKEALRPYDLKDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYD-SRISLASRIVKIETKVESMELKL 2249
            L++++K AIR +R++R++VA RKF++  +PYD+KD+IEQYS GH++M+ R+K LQ RLD   G+   +     D  R+++A R++ IE K+  +E K+
Sbjct:  386 LNSSQKVAIRVLRRMRYYVARRKFQQTRKPYDVKDVIEQYSQGHLNMMVRLKELQRRLDQTLGKPAHR--NNIDRHRMTIAQRLLVIEYKITDLESKV 481          
The following BLAST results are available for this feature:
BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCNQ45.846e-13242.71potassium voltage-gated channel subfamily Q member... [more]
KCNQ55.950e-11355.66potassium voltage-gated channel subfamily Q member... [more]
KCNQ59.531e-11256.04potassium voltage-gated channel subfamily Q member... [more]
KCNQ51.015e-11156.04potassium voltage-gated channel subfamily Q member... [more]
KCNQ56.403e-11156.04potassium voltage-gated channel subfamily Q member... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kqt-11.802e-13163.67KQT-1 potassium channel; Potassium channel, KvQLT ... [more]
kqt-11.529e-13063.67KQT-1 potassium channel; Potassium channel, KvQLT ... [more]
kqt-32.090e-10453.75Potassium channel, KvQLT family [Source:UniProtKB... [more]
kqt-32.090e-10453.75Potassium channel, KvQLT family [Source:UniProtKB... [more]
kqt-34.288e-10453.75Potassium channel, KvQLT family [Source:UniProtKB... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCNQ1.497e-13564.20gene:FBgn0033494 transcript:FBtr0299832[more]
KCNQ5.991e-13564.20gene:FBgn0033494 transcript:FBtr0310093[more]
KCNQ6.444e-13564.20gene:FBgn0033494 transcript:FBtr0310095[more]
KCNQ8.278e-13564.20gene:FBgn0033494 transcript:FBtr0301443[more]
KCNQ1.108e-13464.20gene:FBgn0033494 transcript:FBtr0310096[more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnq5a1.308e-11358.73potassium voltage-gated channel, KQT-like subfamil... [more]
kcnq5b1.412e-11357.45potassium voltage-gated channel, KQT-like subfamil... [more]
kcnq1.19.285e-10555.05potassium voltage-gated channel, KQT-like subfamil... [more]
kcnq1.11.942e-10455.05potassium voltage-gated channel, KQT-like subfamil... [more]
kcnq1.12.960e-10455.05potassium voltage-gated channel, KQT-like subfamil... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000046831.15.182e-10857.68potassium voltage-gated channel subfamily KQT memb... [more]
ENSXETT00000046823.12.025e-10757.68potassium voltage-gated channel subfamily KQT memb... [more]
kri12.887e-10653.82KRI1 homolog [Source:Xenbase;Acc:XB-GENE-6036517][more]
ENSXETT00000046791.13.183e-10657.68potassium voltage-gated channel subfamily KQT memb... [more]
kri13.449e-10653.82KRI1 homolog [Source:Xenbase;Acc:XB-GENE-6036517][more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kcnq54.191e-11256.04potassium voltage-gated channel, subfamily Q, memb... [more]
Kcnq52.268e-11156.04potassium voltage-gated channel, subfamily Q, memb... [more]
Kcnq52.713e-11152.92potassium voltage-gated channel, subfamily Q, memb... [more]
Kcnq53.561e-11156.96potassium voltage-gated channel, subfamily Q, memb... [more]
Kcnq11.487e-10352.91potassium voltage-gated channel, subfamily Q, memb... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P56696|KCNQ4_HUMAN2.808e-13142.71Potassium voltage-gated channel subfamily KQT memb... [more]
sp|Q9JK45|KCNQ5_MOUSE1.586e-11056.04Potassium voltage-gated channel subfamily KQT memb... [more]
sp|Q9NR82|KCNQ5_HUMAN3.075e-11056.04Potassium voltage-gated channel subfamily KQT memb... [more]
sp|P70057|KCNQ1_XENLA1.308e-10549.86Potassium voltage-gated channel subfamily KQT memb... [more]
sp|Q9MYS6|KCNQ1_RABIT6.647e-10252.91Potassium voltage-gated channel subfamily KQT memb... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1D1VIK01.428e-16650.43Uncharacterized protein OS=Ramazzottius varieornat... [more]
A0A267DKX44.463e-16563.99Ion_trans domain-containing protein OS=Macrostomum... [more]
A0A267E7M95.327e-16263.99Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A267FYJ71.733e-16163.99Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A4S2MFA02.862e-15870.03Uncharacterized protein OS=Opisthorchis felineus O... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnq5b5.655e-11457.14potassium voltage-gated channel subfamily KQT memb... [more]
kcnq5b1.158e-11358.10potassium voltage-gated channel subfamily KQT memb... [more]
kcnq5a2.846e-11358.73potassium voltage-gated channel subfamily Q member... [more]
kcnq5a3.473e-11357.76potassium voltage-gated channel subfamily Q member... [more]
kcnq5a5.423e-11357.76potassium voltage-gated channel subfamily Q member... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnq1.17.731e-9758.57potassium voltage-gated channel, KQT-like subfamil... [more]
ENSPMAT00000001128.11.818e-9363.27pep scaffold:Pmarinus_7.0:GL481044:147302:155278:-... [more]
ENSPMAT00000009923.11.178e-7264.37pep scaffold:Pmarinus_7.0:GL476399:1077789:1091635... [more]
ENSPMAT00000009926.12.207e-6961.20pep scaffold:Pmarinus_7.0:GL476399:1078231:1091635... [more]
kcnq45.831e-3459.34potassium voltage-gated channel, KQT-like subfamil... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO427992.677e-7850.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
SHAKR91.812e-2932.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO480591.293e-2529.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
SHAK31.395e-2532.49Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
SHAKR127.834e-2429.02Potassium channel; Predicted protein [Source:UniP... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnq5a1.715e-11256.83potassium voltage-gated channel subfamily KQT memb... [more]
kcnq5a1.130e-11156.83potassium voltage-gated channel subfamily KQT memb... [more]
kcnq5a1.470e-11157.78potassium voltage-gated channel subfamily KQT memb... [more]
kcnq5b4.143e-10956.21potassium voltage-gated channel subfamily KQT memb... [more]
kcnq5b4.697e-10956.21potassium voltage-gated channel subfamily KQT memb... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000048964.10.000e+093.20SMESG000048964.1[more]
SMESG000046611.10.000e+053.88SMESG000046611.1[more]
SMESG000046611.10.000e+053.07SMESG000046611.1[more]
SMESG000022978.17.768e-10458.72SMESG000022978.1[more]
SMESG000040474.11.861e-10355.41SMESG000040474.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007451 ID=SMED30007451|Name=Potassium voltage-gated channel subfamily KQT member 5|organism=Schmidtea mediterranea sexual|type=transcript|length=2682bp
CTGAATTTCTATCCAATCACCATCAAGTAAATGTCTATAGTTATTGATAT
TTTCGAATAGTTGATCTTTGTAAAATGAACTATGCGATAAAATTCTAGTA
TTTTGAAATGGATATTTTCCGGCATCAAGAAGTGCATCCATCTGAGAATA
GTGTCTGTATTGACGTCGATACTTTGCACATTTCTGAGGAAAATAATAAT
TATGCCAACTCTGGATTTGATACAAATCTTTCTGGATTTAGCCCAACTGA
AAACATGAATTACAAATGCCGATCGAATTCTCTATCAAAAGCTAACGATT
CCCGACATGAAGCCTCAAGTAAAATTCGAGAAAAACGCCAGAGATATGCG
AAAAATTCACCGAGACACCAAAAAACCATATCGGGATTAATCAACATTGC
CGAAGACAAAGAACACATTCAGTTGGAATCGAAAAACTCCAAAACCAGTG
CTCAATTCGATGACGACTCAGAAGCGAATCCGCTTAATAAATTGTATCGA
TCAAACTCTAAGGAATTGCCCAATATGCATTTCGTTCCAAGAAAATCTCT
ACTAGGAAAACCGATTGTCGGACGGAGTTATTCTCGACAAGATGCTCAAT
ATAGAAAATTACAATCAAAAATTTATAATTTCTTAGAAAGACCTAAAAAT
TGGAATGCTGTCGGATATCACATAATTGTATTTGCTTCTGTATTCACATG
CCTCGTTCTAAGTGTTCTTTCTACAGTCGACGATGTTGGAAATTATGCTG
GAGAAATGCTATTCTATGTTGAATTATCAGTACTCTTTTGGTTTTTCACT
GAGTACTGCCTGCGATTGTGGAGTGCCGGATGCAGATCAAGATATCAAAC
ATGGAGGGGTCGGCTATTGTTTGCCCGGCAACCATTTTGTCTTGTAGATC
TTGTGGTTATCCTGGCCAGCATAATAGTGTTAGCACTTGGCAGTGACAGA
CAAATGTTTGCAGCAAGTGCTCTTCGGGGTCTCAGGTTCTTTCAAATACT
CAGAATGATTCGCATGGACCGCAGGGGTGGGTCATGGAAATTACTTGCAT
CAGTCGTATGGGCTCACAGACAAGAGCTTTTTACAACTATCTATATCGGA
TTCCTTGTTCTCGTATTCAGTTCTTTCCTCATATATTTGGCTGAGAAAGA
TGAGAGAGATAAAATAAAGTCATACGCAGACGCTCTCTGGTGGGGAGTGA
TCACTCTCTGTACGGTGGGATATGGAGACACAGTTCCCAAAACGGCTCTG
GGAAAATTAATTGCTGGTTGCTGTGCTATTGCTGGAATTTCTTTTTTCGC
ATTACCAGCGGGAATTTTAGGATCTGGATTTGCTTTAAAAGTTCAACAGC
ATCAGCGACACAAGCATTTAATAAGGCGGCGAATGCCTGCTGCAACCTTG
ATCCAGTGTTTGTGGAGATGCTATTCGAGTGATCCTCAATCAACCTCTGT
AGCTACATGGAAGCCCCATCTGAAAAGTTTCCGAGCGTCAACGATTGAAA
AAAACACTTCAGGTCTTGATTCTTCTATTCTTTCATCAATCAGTGCTGTA
GACAGATTAGCGAAGTTTTCACGTATTTCAACCATCAAAAGACGTTGTGA
AAAGCTTGCCAACACGAGTTCCTCAGGTCAAAGTCTCTCACACTCATTCA
GTAGCAGTACTATCGTTTTAAATTCTTATAATAGAAATAATGGCACAAAT
GATAATGAACCTGTAGATGAAGATCCTGACGATGAAGACAGTAATAATTT
CAATATGTATTCTACGCCTGCATTCTCTATTTCACGGCGGAATGCACTGG
CACAATCAGTAGAGAAATACAGGGAAGACGATCAATCGACCAAAAAGAAA
TTTGGTATTCTTGACGACTTTTTTCTAAATCGCTACACTTCGATGGCTTC
CATGACTCGAGATGAAATATTAGCCGAAGATTGGGACGCTTTGTTGCCGA
AGAGGGAATTGTCTAATACCGAAAAACATGCAATTAGATTTATTAGAAAA
GTTAGATTTTTTGTGGCTTCCAGAAAATTTAAAGAAGCATTAAGGCCTTA
TGATTTGAAAGACATAATTGAACAATATTCCTCTGGGCATGTTGACATGC
TTGCAAGAATCAAAGGATTACAATTACGGCTGGACAATTTATTCGGTAGA
TCGGACGTGAAAATAAGTGAAGGGTATGATTCACGGATTAGTTTAGCCTC
TAGGATTGTAAAGATTGAAACAAAAGTAGAAAGTATGGAGCTCAAACTTG
ACAAATTCATTCAACTATATAAACAACACAATATCAGCAACTCAAATCAT
AATCAACACAATGTTCCCAATTCAACTCATTTCCGTCAATTTACCCCAGA
AATCGTTCCCCATCCTTCCTCGCCGTTGATTTATCATCGGCCAACTTGTG
TTGGTTTCGTTGAGAATTTCAATACTTCATCTGAAACAAGACAGCAACAA
ACAGATCATAAATCTCAAACAATCTCAAAAAGCTTTGACCCGATTCAGGG
CATTTCCCCCACTTCCGCCAGTAACACAGATATTACGAGGAAAAAATTTG
ACGAAGTTTAATCACCATAATTTATATTATTTCATTTTAATCTCTTCCTT
CTACACTCTATTATATTGTTATTAATATTATTACTATTATTACTATTTAA
CTATTTATGATATTTATATTTTTCTATTCGCA
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protein sequence of SMED30007451-orf-1

>SMED30007451-orf-1 ID=SMED30007451-orf-1|Name=SMED30007451-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=818bp
MDIFRHQEVHPSENSVCIDVDTLHISEENNNYANSGFDTNLSGFSPTENM
NYKCRSNSLSKANDSRHEASSKIREKRQRYAKNSPRHQKTISGLINIAED
KEHIQLESKNSKTSAQFDDDSEANPLNKLYRSNSKELPNMHFVPRKSLLG
KPIVGRSYSRQDAQYRKLQSKIYNFLERPKNWNAVGYHIIVFASVFTCLV
LSVLSTVDDVGNYAGEMLFYVELSVLFWFFTEYCLRLWSAGCRSRYQTWR
GRLLFARQPFCLVDLVVILASIIVLALGSDRQMFAASALRGLRFFQILRM
IRMDRRGGSWKLLASVVWAHRQELFTTIYIGFLVLVFSSFLIYLAEKDER
DKIKSYADALWWGVITLCTVGYGDTVPKTALGKLIAGCCAIAGISFFALP
AGILGSGFALKVQQHQRHKHLIRRRMPAATLIQCLWRCYSSDPQSTSVAT
WKPHLKSFRASTIEKNTSGLDSSILSSISAVDRLAKFSRISTIKRRCEKL
ANTSSSGQSLSHSFSSSTIVLNSYNRNNGTNDNEPVDEDPDDEDSNNFNM
YSTPAFSISRRNALAQSVEKYREDDQSTKKKFGILDDFFLNRYTSMASMT
RDEILAEDWDALLPKRELSNTEKHAIRFIRKVRFFVASRKFKEALRPYDL
KDIIEQYSSGHVDMLARIKGLQLRLDNLFGRSDVKISEGYDSRISLASRI
VKIETKVESMELKLDKFIQLYKQHNISNSNHNQHNVPNSTHFRQFTPEIV
PHPSSPLIYHRPTCVGFVENFNTSSETRQQQTDHKSQTISKSFDPIQGIS
PTSASNTDITRKKFDEV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: molecular function
TermDefinition
GO:0005249voltage-gated potassium channel activity
GO:0005216ion channel activity
GO:0005267potassium channel activity
Vocabulary: cellular component
TermDefinition
GO:0008076voltage-gated potassium channel complex
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0055085transmembrane transport
GO:0006811ion transport
GO:0006813potassium ion transport
GO:0006810transport
GO:0071805potassium ion transmembrane transport
Vocabulary: INTERPRO
TermDefinition
IPR003937K_chnl_volt-dep_KCNQ
IPR028325VG_K_chnl
IPR013821K_chnl_volt-dep_KCNQ_C
IPR005821Ion_trans_dom
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003937Potassium channel, voltage dependent, KCNQPRINTSPR01459KCNQCHANNELcoord: 248..267
score: 58.23
coord: 228..247
score: 56.29
coord: 310..329
score: 65.65
NoneNo IPR availablePRINTSPR00169KCHANNELcoord: 382..408
score: 40.28
coord: 323..346
score: 28.31
coord: 353..375
score: 48.41
coord: 294..320
score: 16.61
coord: 220..243
score: 29.47
NoneNo IPR availableGENE3DG3DSA:1.10.287.70coord: 185..411
e-value: 8.9E-58
score: 197.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 60..78
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 775..817
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 775..808
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 57..87
NoneNo IPR availablePANTHERPTHR11537:SF259KCNQ POTASSIUM CHANNEL, ISOFORM Fcoord: 103..744
NoneNo IPR availableSUPERFAMILYSSF81324Voltage-gated potassium channelscoord: 185..409
NoneNo IPR availableTMHMMTMhelixcoord: 325..344
NoneNo IPR availableTMHMMTMhelixcoord: 260..279
NoneNo IPR availableTMHMMTMhelixcoord: 217..239
NoneNo IPR availableTMHMMTMhelixcoord: 185..207
NoneNo IPR availableTMHMMTMhelixcoord: 384..406
IPR005821Ion transport domainPFAMPF00520Ion_transcoord: 188..409
e-value: 1.2E-23
score: 83.6
IPR013821Potassium channel, voltage dependent, KCNQ, C-terminalPFAMPF03520KCNQ_channelcoord: 615..724
e-value: 1.7E-31
score: 109.6
IPR028325Voltage-gated potassium channelPANTHERPTHR11537VOLTAGE-GATED POTASSIUM CHANNELcoord: 103..744