MFS domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30007407 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A419Q2S4 (Uncharacterized protein OS=Clonorchis sinensis OX=79923 GN=CSKR_11621s PE=4 SV=1) HSP 1 Score: 156.377 bits (394), Expect = 1.535e-37 Identity = 120/457 (26.26%), Postives = 216/457 (47.26%), Query Frame = 3 Query: 111 ITIFCAVFISIIISGKGRCFGVVLAHFHNKTCTSAAHRCSISSLNFIGDLGVAIALAGSPFVTGFLIRLQTPALGGRISVQCA-IIIILGCLSTNFIIQPDSLIVTDSIIQGIGTSVIVSVIAIRLTEIFPRENKYHVLVSAFTDAGPWGTVIMCPLFGVILQTTHWQQVYLFFXXXXXXXXXXXXXXEPKNYDQPAVSTFRIEKSFKAESSSKCPDHPDQQCKSYEEVNEIEFWENDQSIYSVSSDEASEEVKRPSIASEV-----PHAPEIRNFFFNPETWNVLRESSSI-IWLIERALHTMILYNVVLNLVDYMVVEIQESLEKASLIMMSFGGGEVIGFVIAVGLGDQLRHHLLHIYTIATGILTVIFMSWHITQAIHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFFL 1460 + +F + I I GK R FG+ +A H S+ + S+S LN+IGD ++ PF T ++RL P R ++ A + I C+++ + P L +T +I+ GIG+++++ ++ + F + +++HVL +AF GP+G ++ PLF + WQ+ ++F IL + T+ +F D Q S E+ E E+ + + + K+PS+A+ + P A + R + F + + LR + + +W ER LH +++Y +++NL Y+ + L + + + + FG GE I F I +GD++R L +Y I G + + I Q + D + L+ + G + + + YA AE+V+ G IA+P+T+ +G+I AP SG VI Y+ FF+ Sbjct: 38 VVLFVSAVNVIFIGGKRRAFGIFVAALH-----SSYNETSMSELNWIGDSYASLGFFLMPFATTAIVRLNRPY---RFTMFLAGVTIFTSCMTSASVPDPGYLFLTHTILHGIGSTLVLCGCSLVTGDYFDKTHRFHVLATAFVSGGPYGVLLFGPLFSYWIHDYSWQEAFVFSGILFLFV------------------TWLGAVTFLPR---------DMQEYSRAELELAEPLEDRDA----GKKDELRKPKKPSVATNIYLHDQPKASDGRGWAFC--SVDHLRNNPQVFLWAFERLLHNVVIYGLLMNLTAYVTQSLNNELIRGAKVNLYFGIGESIIFTIGALIGDRIRGKLPIVYLIGAGFSALFLI---IVQRSYTDI---NVVYVLSGLTGGAVGVGNTFLYATAEEVMLVHGSIAFPMTKMVAGVGMIIAPAFSGSVIDGYGYRGFFI 447
BLAST of MFS domain-containing protein vs. TrEMBL
Match: H2KPP0 (Monocarboxylate transporter 9 OS=Clonorchis sinensis OX=79923 GN=CLF_102350 PE=4 SV=1) HSP 1 Score: 155.221 bits (391), Expect = 3.488e-37 Identity = 115/457 (25.16%), Postives = 212/457 (46.39%), Query Frame = 3 Query: 111 ITIFCAVFISIIISGKGRCFGVVLAHFHNKTCTSAAHRCSISSLNFIGDLGVAIALAGSPFVTGFLIRLQTPALGGRISVQCAIIIILGCLSTNFIIQPDSLIVTDSIIQGIGTSVIVSVIAIRLTEIFPRENKYHVLVSAFTDAGPWGTVIMCPLFGVILQTTHWQQVYLFFXXXXXXXX-XXXXXXEPKNYDQPAVSTFRIEKSFKAESSSKCPDHPDQQCKSYEEVNEIEFWENDQSIYSVSSDEASEEVKRPSIASEV-----PHAPEIRNFFFNPETWNVLRESSSI-IWLIERALHTMILYNVVLNLVDYMVVEIQESLEKASLIMMSFGGGEVIGFVIAVGLGDQLRHHLLHIYTIATGILTVIFMSWHITQAIHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFFL 1460 + +F + I I GK R FG+ +A H S+ + S+S LN+IGD ++ PF T ++RL P I + I C+++ + P L +T +I+ GIG+++++ ++ + F + +++HVL +AF GP+G ++ PLF + WQ+ ++F IL + + P++ + + + + + + K DE + K+PS+A+ + P A + R + F + + LR + + +W ER LH +++Y +++NL Y+ + L + + + + FG GE I F I +GD++R L +Y I G + + I Q + D + L+ + G + + + YA AE+V+ G IA+P+T+ +G+I AP SG VI Y+ FF+ Sbjct: 38 VVLFVSAVNVIFIGGKRRAFGIFVAALH-----SSYNETSMSELNWIGDSYASLGFFLMPFATTAIVRLNRPYR--FIMFLAGVTIFTSCMTSASVPDPGYLFLTHTILHGIGSTLVLCGCSLVTGDYFDKTHRFHVLATAFVSGGPYGVLLFGPLFSYWIHDYSWQEAFVFSGILFLFVTWLGAVTFLPRDMQEYSRAELELAEPLADRDAGK-------------------------------KDELRKP-KKPSVATNIYLHDQPKASDGRGWAFC--SVDHLRNNPQVFLWAFERLLHNVVIYGLLMNLTAYVTQSLNNELIRGAKVNLYFGIGESIIFTIGALIGDRIRGKLPIVYLIGAGFSALFLI---IVQRSYTDI---NVVYVLSGLTGGAVGVGNTFLYATAEEVMLVHGSIAFPMTKMVAGVGMIIAPAFSGSVIDGYGYRGFFI 447
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A4S2MEA9 (MFS domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000598 PE=4 SV=1) HSP 1 Score: 152.14 bits (383), Expect = 4.532e-36 Identity = 114/452 (25.22%), Postives = 208/452 (46.02%), Query Frame = 3 Query: 111 ITIFCAVFISIIISGKGRCFGVVLAHFHNKTCTSAAHRCSISSLNFIGDLGVAIALAGSPFVTGFLIRLQTPALGGRISVQCA-IIIILGCLSTNFIIQPDSLIVTDSIIQGIGTSVIVSVIAIRLTEIFPRENKYHVLVSAFTDAGPWGTVIMCPLFGVILQTTHWQQVYLFFXXXXXXXX-XXXXXXEPKNYDQPAVSTFRIEKSFKAESSSKCPDHPDQQCKSYEEVNEIEFWENDQSIYSVSSDEASEEVKRPSIASEVPHAPEIRNFFFNPETWNVLRESSSIIWLIERALHTMILYNVVLNLVDYMVVEIQESLEKASLIMMSFGGGEVIGFVIAVGLGDQLRHHLLHIYTIATGILTVIFMSWHITQAIHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFFL 1460 + +F + I I GK R FG+ +A H S+ + S+S LN+IGD ++ PF T ++RL P R ++ A + I C+++ + P L +T +I+ GIG+++++ ++ + F + +++HVL +AF GP+G ++ PLF + WQ+ ++F IL + + P++ + + + + + K +Q K V ++ D+ R V H +RN NP+ + +W ER LH +++Y +++NL Y+ + L + + + + FG GE I F I +GD++R L +Y I + + I Q + D + L+ + G + + + YA AE+V+ G IA+P+T+ +G+I AP SG VI Y+ FF+ Sbjct: 38 VVLFVSAINVIFIGGKRRAFGIFVAALH-----SSYNETSMSELNWIGDSYASLGFFLMPFATTAIVRLNRPY---RFTMFLAGVTIFTSCMTSASVPDPGYLFLTHTILHGIGSTLVLCGCSLVTGDYFDKTHRFHVLATAFVSGGPYGVLLFGPLFSYWIHDYSWQEAFIFSGILFLFVTWLGAVTFLPRDMHEYSRAELTLSEPLAERDVGK--KDSLKQSKKQSVVANVDL-----------RDQPKASDGRGWAFCSVDH---LRN---NPQVF---------LWAFERLLHNVVVYGLLMNLTAYVTQSLNNELTRGAKVNLYFGIGESIIFTIGALIGDRIRGKLPLVYLIGAAFSALFLI---IVQRSYTDI---NVVYVLSGLTGGAVGVGNTFLYATAEEVMLVHGSIAFPMTKMVAGVGMIIAPAFSGSVIDGYGYRGFFI 447
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A5J4NWZ5 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0013706 PE=4 SV=1) HSP 1 Score: 150.984 bits (380), Expect = 9.311e-36 Identity = 115/443 (25.96%), Postives = 205/443 (46.28%), Query Frame = 3 Query: 141 IIISGKGRCFGVVLAHFHNKTCTSAAHRCSISSLNFIGDLGVAIALAGSPFVTGFLIRLQTPALGGRISVQCA-IIIILGCLSTNFIIQPDSLIVTDSIIQGIGTSVIVSVIAIRLTEIFPRENKYHVLVSAFTDAGPWGTVIMCPLFGVILQTTHWQQVYLFFXXXXXXXXXXXXXXEPKNYDQPAVSTFRIEKSFKAESSSKCPDHPDQQCKSYEEVNEIEFWENDQSIYSVSSDEASEEVKRPS--IASEVPHAPEIRNFFFNPETWNVLRESSSIIWLIERALHTMILYNVVLNLVDYMVVEIQESLEKASLIMMSFGGGEVIGFVIAVGLGDQLRHHLLHIYTIATGILTVIFMSWHITQAIHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFFL 1460 I I GK R FG+ +A H +A + S++ LN+IGD ++ PF T +I L P R+++ A +II + C+++ + P L +T +I+ GIG+++I+ ++ + F + ++YHVL +AF GP+G +I PLF + WQQ +++ IL ++ + TF F Y E + EN+ +V E + RP+ + +P A + R + F ++ ++W ER L +++Y +++NL Y+ + + + + + + FG GE F + +GD++R HL +Y I + I Q + D + LA G + + + YA AE+V+ G IA+P+T+ +G++ AP+ SG VI Y+ FF+ Sbjct: 48 ICIGGKRRAFGIFIAALH-----TAYNETSMTELNWIGDSYASLGFFLMPFATTAIITLNRPY---RMTMFLAGLIIFVSCMTSAAVPDPGYLFLTHTILHGIGSTLILCGTSLVTGDYFDKTHRYHVLATAFVSGGPYGVLIFGPLFSYWIHDYSWQQAFVYSGILFLLTTWL------------GAITFLPRYMF-----------------DYMEAVDGNGSENEM---AVKKPETKPDNSRPTPILLRNLPKASDGRGWAFC-SVEHIRHNPQIVLWSFERLLQNVVVYGLLMNLTSYVSEALNNEIIRGAKVNLYFGIGESFVFTVGALIGDRIRGHLPLVYLIGAAFAALFLF---IVQRSYTDI---NVIYLLAGFTGAAVGVGNTFLYATAEEVMLVHGSIAFPMTKMVAGVGMLIAPVFSGGVIDKFGYRGFFI 443
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A1S8WM16 (Transporter, major facilitator family protein OS=Opisthorchis viverrini OX=6198 GN=X801_08712 PE=4 SV=1) HSP 1 Score: 150.599 bits (379), Expect = 1.553e-35 Identity = 117/454 (25.77%), Postives = 212/454 (46.70%), Query Frame = 3 Query: 111 ITIFCAVFISIIISGKGRCFGVVLAHFHNKTCTSAAHRCSISSLNFIGDLGVAIALAGSPFVTGFLIRLQTPALGGRISVQCA-IIIILGCLSTNFIIQPDSLIVTDSIIQGIGTSVIVSVIAIRLTEIFPRENKYHVLVSAFTDAGPWGTVIMCPLFGVILQTTHWQQVYLFFXXXXXXXX-XXXXXXEPKNYDQPAVSTFRIEKSFKAESSSKCPD--HPDQQCKSYEEVNEIEFWENDQSIYSVSSDEASEEVKRPSIASEVPHAPEIRNFFFNPETWNVLRESSSIIWLIERALHTMILYNVVLNLVDYMVVEIQESLEKASLIMMSFGGGEVIGFVIAVGLGDQLRHHLLHIYTIATGILTVIFMSWHITQAIHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFFL 1460 + +F + I I GK R FG+ +A H S+ + S+S LN+IGD ++ PF T ++RL P R ++ A + I C+++ + P L +T +I+ GIG+++++ ++ + F + +++HVL +AF GP+G ++ PLF + WQ ++F IL + + I P++ + + + + + + K D P +Q + +IY +AS+ R V H +R NP+ + +W ER LH +++Y +++NL Y+ + L + + + + FG GE I F I +GD++R L +Y I + + I Q + D + L+ + G + + + YA AE+V+ G IA+P+T+ +G+I AP SG VI Y+ FF+ Sbjct: 38 VVLFVSAINVIFIGGKRRAFGIFVAALH-----SSYNETSMSELNWIGDSYASLGFFLMPFATTAIVRLNRPY---RFTMFLAGVTIFTSCMTSASVPDPSYLFLTHTILHGIGSTLVLCGCSLVTGDYFDKTHRFHVLATAFVSGGPYGVLLFGPLFSYWIHDYSWQDAFIFSGILFLFVTWLGAVIFLPRDMHEYSRAELTLSEPLADRDAGKKDDMRKPKKQSAA-------------ANIYLRDQPKASD--GRGWAFCSVDH---LRT---NPQVF---------LWAFERLLHNIVIYGLLMNLTAYVTQSLNNELIRGAKVNLYFGIGESIIFTIGALIGDRIRGKLPIVYLIGAAFSALFLI---IVQRSYTDI---NVVYVLSGLTGGAVGVGNTFLYATAEEVMLVHGSIAFPMTKMVAGVGMIIAPAFSGSVIDGYGYRGFFI 447
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000065239.1 (SMESG000065239.1) HSP 1 Score: 613.224 bits (1580), Expect = 0.000e+0 Identity = 332/332 (100.00%), Postives = 332/332 (100.00%), Query Frame = 3 Query: 567 MCPLFGVILQTTHWQQVYLFFXXXXXXXXXXXXXXEPKNYDQPAVSTFRIEKSFKAESSSKCPDHPDQQCKSYEEVNEIEFWENDQSIYSVSSDEASEEVKRPSIASEVPHAPEIRNFFFNPETWNVLRESSSIIWLIERALHTMILYNVVLNLVDYMVVEIQESLEKASLIMMSFGGGEVIGFVIAVGLGDQLRHHLLHIYTIATGILTVIFMSWHITQAIHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFFLIQXXXXXXXXXXXXXXXXXXXQNKLVHSESCLPK 1562 MCPLFGVILQTTHWQQVYLFFAILLVIAIIITSIVEPKNYDQPAVSTFRIEKSFKAESSSKCPDHPDQQCKSYEEVNEIEFWENDQSIYSVSSDEASEEVKRPSIASEVPHAPEIRNFFFNPETWNVLRESSSIIWLIERALHTMILYNVVLNLVDYMVVEIQESLEKASLIMMSFGGGEVIGFVIAVGLGDQLRHHLLHIYTIATGILTVIFMSWHITQAIHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFFLIQTILTFIRLVLLIVLIFKLKQNKLVHSESCLPK Sbjct: 1 MCPLFGVILQTTHWQQVYLFFAILLVIAIIITSIVEPKNYDQPAVSTFRIEKSFKAESSSKCPDHPDQQCKSYEEVNEIEFWENDQSIYSVSSDEASEEVKRPSIASEVPHAPEIRNFFFNPETWNVLRESSSIIWLIERALHTMILYNVVLNLVDYMVVEIQESLEKASLIMMSFGGGEVIGFVIAVGLGDQLRHHLLHIYTIATGILTVIFMSWHITQAIHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFFLIQTILTFIRLVLLIVLIFKLKQNKLVHSESCLPK 332
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000014825.1 (SMESG000014825.1) HSP 1 Score: 259.61 bits (662), Expect = 3.726e-80 Identity = 152/463 (32.83%), Postives = 263/463 (56.80%), Query Frame = 3 Query: 90 FTNLR--KHITIFC-AVFISIIISGKGRCFGVVLAHFHNKTCTSAAHRCSISSLNFIGDLGVAIALAGSPFVTGFLIRLQTPALGGRISVQCAIIIILGCLSTNFIIQPDSLIVTDSIIQGIGTSVIVSVIAIRLTEIFPRENKYHVLVSAFTDAGPWGTVIMCPLFGVILQTTHWQQVYLFFXXXXXXXXXXXXXXEPKNYDQPAVSTFRIEKSFKAESSSKCPDHPDQQCKSYEEVNEIEFWENDQSIYSVSSDEASEEVKRPSIASEVPHAPEIRNFFFNPETWNVLRESSSIIWLIERALHTMILYNVVLNLVDYMVVEIQESLEKASLIMMSFGGGEVIGFVIAVGLGDQLRHHLLHIYTIATGILTVIFMSWHITQA-IHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFFLIQ 1466 F +L+ K I+I C + + ++++GK RCF V+ A N+TC + C +++LN+I L I + G+PF+T IR+ + LGG+++ Q +I+ LG L T F+ P+SL VTD++IQGI TSV++ +++ +L ++P +N H V ++ PW VI+CPL+G ++ WQ YL + L+++ ++ I+EPK VS E + D + ++ EE++ ++ D+S Y D E + PS+ N V+ +S ++W IERAL + +N+++NLV YM + E + +AS+IM++ G G ++GF+ LG ++R +L IY +A+ +L + F+ W I + + F+ DAHF+ ++ G A ++ +Y +AED++ RP II+ LT+ Q+LGL+ P++SG++IQ D + SFF +Q Sbjct: 18 FASLKSLKVISIVCLTISLCVVLNGKTRCFSVLAAELQNQTCNTIKDTCGMATLNWIAFLSEMIIVGGNPFITNMFIRVHSGVLGGKVTFQFCLILTLGTLLTGFVGDPESLFVTDTLIQGISTSVLLGLVSFKLVHMYPDDNPNHKTVLLLSEIAPWFGVILCPLYGTLVSVYGWQSSYLLISFLIMVICVLAGIIEPK------VSA--------TEEQEENEDSDNSSIQNTEEIDSQTYF--DKSDYWEIEDVGEMECQHPSLL----------QLLLNVNISQVVGKSEVVVWFIERALMIIAEFNLIINLVHYMTSVLLEPILQASMIMITLGAGNIMGFLTIYVLGSKIRKYLPRIYILASVMLVISFIVWQIYGSQTDLILFTVPDAHFVVIVIGAFSAISTAQSYYVAEDIIERPRIISVSLTKLAQSLGLLIGPISSGMLIQIDFFHSFFSVQ 454
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000011418.1 (SMESG000011418.1) HSP 1 Score: 125.946 bits (315), Expect = 2.831e-31 Identity = 115/458 (25.11%), Postives = 200/458 (43.67%), Query Frame = 3 Query: 105 KHITIFCAVFISI---IISGKGRCFGVVLAHFHNKTCTSAAHRCSISSLNFIGDLGVAIALAGSPFVTGFLIRLQTPALGGRISVQCAIIIILGCLSTNFIIQPDSLIVTDSIIQGIGTSVIVSVIAIRLTEIFPRENKYHVLVSAFTDAGPWGTVIMCPLFGVILQTTHWQQVYLFFXXXXXXXXXXXXXXEPKNYDQPAVSTFRIEKSFKAESSSKCPDHPDQQCKSYEEVNEIEFWENDQSIYSVSSDEASEEVKRPSIASEVPHAPEIRNFFFNPETWNVLRESSSIIWLIERALHTMILYNVVLNLVDYM--VVEIQESLEKASLIMMSFGGGEVIGFVIAVGLGDQLRHHL--LHIYTIATGILTVIFMSWHITQAIHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFF 1457 K ++IF V +I I GK R FG+ ++ F S + S+ LN++GD A+A PF+T F+ R ++ G + +I++ C+ T+F+ L +T +++ GIG++ I+S A+ + E F + ++YHVL ++ T GP+G++I PL+G ++Q W+ + + F +E S + PD Y++ EIE +E P ++ N + + +W I+R + ILY +++NL D + ++ E+LE + I + G GE I F I+ +GD++R L H+ A +L +I M I +FS + G + YA +E++ G I+ PL+ A G+I AP+ SGL+I + F Sbjct: 15 KQLSIFILVVATINIIFIGGKRRTFGIFISAFR-----STFNGTSMVELNWVGDSYSAVAFFLMPFITSFVHRNRSYQKG---MLAASILVFCSCMLTSFVTNAAELFITHTVLHGIGSAFILSTSALIIGEYFDKNHRYHVLATSLTTGGPYGSLIFGPLYGFMVQHYDWRFTF-----------------------RVIAILFFVEISAGILAYVPKPD--------YQKSEEIENYEGA--------------------------FPSLKYLIQNKQIF---------LWGIDRICTSSILYGLLMNLTDLLRSMLNGTENLEGGAKINLMMGVGESIIFTISAVIGDKIRGKLPFFHLIGAAFTLLMLILMKTVSYYPYAIIAFS--------IFLGAGAGVGNCMLYASSEEITFLHGSISLPLSNMMMAFGMIIAPIFSGLLIDMYGFLGLF 390
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000046854.1 (SMESG000046854.1) HSP 1 Score: 75.0998 bits (183), Expect = 4.366e-14 Identity = 46/185 (24.86%), Postives = 88/185 (47.57%), Query Frame = 3 Query: 69 PWIQSQNFTNLRKHITIFCAVFISIIISGKGRCFGVVLAHFHNKTCTSAAHRCSISSLNFIGDLGVAIALAGSPFVTGFLIRLQTPALGGRISVQCAIIIILGCLSTNFIIQPDSLIVTDSIIQGIGTSVIVSVIAIRLTEIFPRENKYHVLVSAFTDAGPWGTVIMCPLFGVILQTTHWQQVYL 623 PWI I +F A+ + I + GK R FG+ +A HN + S++ LN+IGD A+ + T +IR + C I+ + CL++ ++ L +T ++ GIG+S+I+SV+ + + E F +KYH+L + G +++ + ++ W++ ++ Sbjct: 36 PWI-----------ILLFSALNV-IFLGGKRRAFGIFIAELHNGVFNTT----SLAELNWIGDSYAALGYLTTTISTAVIIRFHRKYRVFQFIGACCIL--MACLASAYVTSAHWLFLTHTVFHGIGSSLILSVVGLVVGEHFDLNHKYHILATTLVSGGSLASIVFVQFYAYLIDQYGWRKAFV 202 HSP 2 Score: 57.3806 bits (137), Expect = 1.594e-8 Identity = 41/171 (23.98%), Postives = 84/171 (49.12%), Query Frame = 3 Query: 966 IIWLIERALHTMILYNVVLNLVDYMVVEIQESLEKASLIMMSFGGGE----VIGFVIAVGLGDQLRHHLLHIYTIATGILTVIFMSWHITQAIHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFFLIQ 1466 I+W ++R + +++ Y ++LNL DY+ SL M+ F GE + G +++ L ++ I++ ++ + +W I + +F+ + L+ G + + + + E++ PG IAYP + LG++ +P+ S ++ Q +YK FFL+Q Sbjct: 252 ILWTLDRIVTSIVTYGMLLNLADYLRRNSSSLNTSTSLTML-FAAGEATTYIQGAIVSALTKKWFASKLKYLLLISSLLMVICLFAWEILAS----NFTW--SCILSYCSGFCLGPSITFLFPAGEELTTLPGEIAYPFSLAGMGLGMLLSPVLSAVIAQKYKYKWFFLVQ 415
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000026519.1 (SMESG000026519.1) HSP 1 Score: 73.1738 bits (178), Expect = 1.670e-13 Identity = 53/233 (22.75%), Postives = 104/233 (44.64%), Query Frame = 3 Query: 63 KWPWIQSQNFTNLRKHITIFCAVFISIIISGKGRCFGVVLAHFHNKTCTSAAHRCSISSLNFIGDLGVAIALAGSPFVTGFLIRLQTPALGGRISVQCAIIIILGCLSTNFIIQPDSLIVTDSIIQGIGTSVIVSVIAIRLTEIFPRENKYHVLVSAFTDAGPWGTVIMCPLFGVILQTTHWQQVYLFFXXXXXXXXXXXXXXEPKNYDQPAVSTFRIEKSFKAESSSKCPDH 761 K PW N ++ + +F A I + GK R FG +A +++ LN+IGD A+ S ++ + G AI +++ C++++F+ P L +T ++ GIG+S+I+S + + + + F ++ YH+L + G ++I LF ++Q+ W+ ++ L I ++ K+ +Q +E + K S +C H Sbjct: 7 KLPW----NRASVLPWVILFFAALNVIFLGGKRRAFGSFVAEMRRD-----YPNITLTELNWIGDSYAAVGYMTSGISIAIILFFKRRY--GMFQFMGAIWVLVSCVTSSFVPNPHWLFLTHTLFHGIGSSLIISTVGLVVNDHFDSKHPYHILATTLVSGGSVASIIFVTLFASLIQSYGWRYAFIILGCLYFIVNASAALFFRKSNNQ-------VEDTNKKTVSCRCEGH 221 HSP 2 Score: 57.7658 bits (138), Expect = 1.139e-8 Identity = 36/170 (21.18%), Postives = 81/170 (47.65%), Query Frame = 3 Query: 969 IWLIERALHTMILYNVVLNLVDYMVVEIQESLEKASLIMMSFGGGEVIGFVIAVGLG----DQLRHHLLHIYTIATGILTVIFMSWHITQAIHIDSFSNGDAHFLALICGLVMAFTSGYTYALAEDVLCRPGIIAYPLTRFCQALGLIFAPLTSGLVIQFDQYKSFFLIQ 1466 +W I+R + +++ Y ++LNL DYM +++L +++ + F GE I ++I + D + L +I + +++ ++ + I + L + G + + + + E++ PG +AYP++ G++ +PL + + + YK FF +Q Sbjct: 232 LWFIDRVMTSVVTYGLLLNLTDYMY-RTEKNLVRSTTLTTLFASGEAITYLIGATITAITRDFFKDKLRYILLGTSFAMSICLIALEYFKGII------SVCYILCFLAGFTLGPSITFLFPAGEELTRLPGHMAYPISLAGMGFGMLVSPLLTAKIAEIFLYKWFFFVQ 394 The following BLAST results are available for this feature:
BLAST of MFS domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 0
BLAST of MFS domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30007407 ID=SMED30007407|Name=MFS domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1656bpback to top protein sequence of SMED30007407-orf-1 >SMED30007407-orf-1 ID=SMED30007407-orf-1|Name=SMED30007407-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=511bp MKVLEYLSTLKWPWIQSQNFTNLRKHITIFCAVFISIIISGKGRCFGVVLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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