Phosphatidylinositol 4-kinase type 2

Overview
NamePhosphatidylinositol 4-kinase type 2
Smed IDSMED30007394
Length (bp)1628
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Phosphatidylinositol 4-kinase type 2 (SMED30007394) t-SNE clustered cells

Violin plots show distribution of expression levels for Phosphatidylinositol 4-kinase type 2 (SMED30007394) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Phosphatidylinositol 4-kinase type 2 (SMED30007394) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Phosphatidylinositol 4-kinase type 2 (SMED30007394) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30007394

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30007394h1SMcG0016545 dd_Smed_v4_9125_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30007394h1SMcG0016545 dd_Smed_v4_9125_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Human
Match: PI4K2B (phosphatidylinositol 4-kinase type 2 beta [Source:HGNC Symbol;Acc:HGNC:18215])

HSP 1 Score: 327.405 bits (838), Expect = 2.717e-107
Identity = 169/352 (48.01%), Postives = 231/352 (65.62%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            D++  AE A +  I P  I QGSSGSYFV++  ++IIGVFKPK EEPY   NPKW+KY H++CCPCCFGR CLI N GYLSE GA ++D  L L+IVP T++  L S  FN+N ++  KS+ K +  E  P +GRKFHR+G+PPK GS Q+FV  Y+ A            P+   ++++F  +F++LV+LDYIIRNTDR N NWL++++ +   +  D   +  I             IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A VPF + I  L+LP + D  FV+ + ++L  LFK +  F K+ FE QM+V+RGQI NL  ALR  K+P QLV++  + +E
Sbjct:   12 DIMLRAEQAIEVGIFPERISQGSSGSYFVKDPKRKIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCLIPNQGYLSEAGAYLVDNKLHLSIVPKTKVVWLVSETFNYNAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKIGSFQLFVEGYKEA--EYWLRKFEADPLPENIRKQFQSQFERLVILDYIIRNTDRGNDNWLVRYEKQKCEKEIDHKESKWI-------DDEEFLIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSEEIRNLILPYISDMNFVQDLCEDLYELFKTDKGFDKATFESQMSVMRGQILNLTQALRDGKSPFQLVQIPCVIVE 354
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Human
Match: PI4K2B (phosphatidylinositol 4-kinase type 2 beta [Source:HGNC Symbol;Acc:HGNC:18215])

HSP 1 Score: 327.405 bits (838), Expect = 6.184e-106
Identity = 169/352 (48.01%), Postives = 231/352 (65.62%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            D++  AE A +  I P  I QGSSGSYFV++  ++IIGVFKPK EEPY   NPKW+KY H++CCPCCFGR CLI N GYLSE GA ++D  L L+IVP T++  L S  FN+N ++  KS+ K +  E  P +GRKFHR+G+PPK GS Q+FV  Y+ A            P+   ++++F  +F++LV+LDYIIRNTDR N NWL++++ +   +  D   +  I             IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A VPF + I  L+LP + D  FV+ + ++L  LFK +  F K+ FE QM+V+RGQI NL  ALR  K+P QLV++  + +E
Sbjct:  108 DIMLRAEQAIEVGIFPERISQGSSGSYFVKDPKRKIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCLIPNQGYLSEAGAYLVDNKLHLSIVPKTKVVWLVSETFNYNAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKIGSFQLFVEGYKEA--EYWLRKFEADPLPENIRKQFQSQFERLVILDYIIRNTDRGNDNWLVRYEKQKCEKEIDHKESKWI-------DDEEFLIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSEEIRNLILPYISDMNFVQDLCEDLYELFKTDKGFDKATFESQMSVMRGQILNLTQALRDGKSPFQLVQIPCVIVE 450
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Human
Match: PI4K2A (phosphatidylinositol 4-kinase type 2 alpha [Source:HGNC Symbol;Acc:HGNC:30031])

HSP 1 Score: 326.25 bits (835), Expect = 1.533e-105
Identity = 172/358 (48.04%), Postives = 228/358 (63.69%), Query Frame = 1 
Query:  244 IEDVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINS 1317
             E VV  AELA ++ I P  I QGSSGSYFV++    II VFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++F+R+G+PPK GS Q+FV  Y+ A            P+      + L +F++LVVLDYIIRNTDR N NWLIK+   ++S    D +                 IK+AAIDNGLAFP KHPD  R YP+YW+WL  A VPF   I  L+LPK+ D  FV+ + ++L  LFK +  F +  F KQ+AV+RGQI NL  AL+  K+P  LV+M P+ +E   S
Sbjct:  110 FEAVVRQAELAIERCIFPERIYQGSSGSYFVKDPQGRIIAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVEGYKDA--DYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDSSSSRDTD---------WVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARS 456
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Human
Match: AL355315.1 (novel protein)

HSP 1 Score: 294.664 bits (753), Expect = 1.155e-93
Identity = 153/321 (47.66%), Postives = 205/321 (63.86%), Query Frame = 1 
Query:  355 IIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINS 1317
            II VFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++F+R+G+PPK GS Q+FV  Y+ A            P+      + L +F++LVVLDYIIRNTDR N NWLIK+   ++S    D +                 IK+AAIDNGLAFP KHPD  R YP+YW+WL  A VPF   I  L+LPK+ D  FV+ + ++L  LFK +  F +  F KQ+AV+RGQI NL  AL+  K+P  LV+M P+ +E   S
Sbjct:  117 IIAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVEGYKDA--DYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDSSSSRDTD---------WVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARS 426
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Celegans
Match: ZC8.6 (pep chromosome:WBcel235:X:4972575:4997598:-1 gene:WBGene00022501.1 transcript:ZC8.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZC8.6)

HSP 1 Score: 291.197 bits (744), Expect = 4.186e-91
Identity = 167/378 (44.18%), Postives = 223/378 (58.99%), Query Frame = 1 
Query:  295 PTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAX----XXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKW---------------------------------QSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKI-----AAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTL 1302
            P  I QGSSGSYFV+N + EII VFKPK+EEPY S NPKW K+ HR+  PCCFGR CL  N GYLSEVGAS++DE L+L IVP T + +L +  F ++ ++  K++TK  I   +P++GR+FHR+G+P K GS Q+FV  Y+ A       +        PV    Q EF F F+KLV LDYIIRNTDR + NWLIK+                                    ++S+ K D     + +         + + I     AAIDNGLAFP+KHPD+ R YP+ W+ L  A +PF D I  LLLPKL D+ +V ++  +L  +FK +  F K +FEKQM+V+RGQI NL  AL +KK+P QL++M P  +
Sbjct:  127 PQRIAQGSSGSYFVKNMHDEIIAVFKPKNEEPYGSLNPKWLKWIHRVFLPCCFGRSCLPPNQGYLSEVGASLVDEKLKLGIVPPTGVVELAAPTFYYDRIDRAKARTKERIQSRYPNIGRRFHRIGLPEKTGSFQLFVKGYQDAAHWLRTWVNQPETAPPPV---TQREFQFLFEKLVALDYIIRNTDRGSDNWLIKYILADVIDRAPVHNNDVPCDPANAKPQVPGDEKLIDFVDSEAKPDAGTARVVDDPAPAEVEWADVSIPTVDVAAIDNGLAFPFKHPDEWRAYPFGWALLPQAQIPFSDDIVDLLLPKLDDTNWVRELCGDLRRVFKNDKGFDKKIFEKQMSVMRGQIFNLREALMKKKSPYQLIQMPPQLM 501
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Celegans
Match: C56A3.8 (pep chromosome:WBcel235:V:13560278:13561992:1 gene:WBGene00008346.1 transcript:C56A3.8a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C56A3.8)

HSP 1 Score: 202.216 bits (513), Expect = 2.366e-59
Identity = 138/373 (37.00%), Postives = 193/373 (51.74%), Query Frame = 1 
Query:  253 VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPD---QMRIYPYYWS---WLSIASVPFCDRISL-LLLPKLGDSVFVEKMIDNLNLLFKINNHFKKS----VFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPN 1338
            V   A+ A +K I P++IP+GSSGSYFV     EI+GVFKPKDEEP+ S NPKW K+F R+ C CCFGR CLI N GYLSE  ASI+ EML+L++VPTTR+ +L S +F ++                     R F    V PK GS Q++V+ YES          +   +  E   +F   FQK+ ++DY+IRNTDR+  N L++                               I +AAIDNGLAFP +HP+   + R +P+ WS   W      P   R  L LL P+     FV ++  +L  LF+   H   S    +   Q+ V+RGQI NL  A+   ++P ++    P+ +    S+D ++ N
Sbjct:   39 VFQKAQEAINKGIQPSLIPEGSSGSYFVYGLEGEIVGVFKPKDEEPFASLNPKWPKFFQRMLCFCCFGRACLIPNTGYLSEAAASIVSEMLQLDVVPTTRIVKLASPSFFYS---------------------RFFGHYDVRPKEGSFQLYVNGYESGNTVFARWNYDKNLLSDEEGAKFQLLFQKMCIVDYVIRNTDRHMDNLLVR-------------------------HVPGEEINLAAIDNGLAFPVRHPECTSRFRSFPFRWSNLPWAQGEFDPVLRRHVLSLLTPQ-----FVHRLCVDLKKLFR---HGIASSNYMLVNSQLRVVRGQIWNLRQAILANESPGEMACRDPIIVS--RSSDIVMSN 355
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Celegans
Match: C56A3.8 (pep chromosome:WBcel235:V:13560494:13561885:1 gene:WBGene00008346.1 transcript:C56A3.8c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C56A3.8)

HSP 1 Score: 201.06 bits (510), Expect = 3.786e-59
Identity = 135/361 (37.40%), Postives = 187/361 (51.80%), Query Frame = 1 
Query:  253 VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPD---QMRIYPYYWS---WLSIASVPFCDRISL-LLLPKLGDSVFVEKMIDNLNLLFKINNHFKKS----VFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTL 1302
            V   A+ A +K I P++IP+GSSGSYFV     EI+GVFKPKDEEP+ S NPKW K+F R+ C CCFGR CLI N GYLSE  ASI+ EML+L++VPTTR+ +L S +F ++                     R F    V PK GS Q++V+ YES          +   +  E   +F   FQK+ ++DY+IRNTDR+  N L++                               I +AAIDNGLAFP +HP+   + R +P+ WS   W      P   R  L LL P+     FV ++  +L  LF+   H   S    +   Q+ V+RGQI NL  A+   ++P ++    P+ +
Sbjct:   39 VFQKAQEAINKGIQPSLIPEGSSGSYFVYGLEGEIVGVFKPKDEEPFASLNPKWPKFFQRMLCFCCFGRACLIPNTGYLSEAAASIVSEMLQLDVVPTTRIVKLASPSFFYS---------------------RFFGHYDVRPKEGSFQLYVNGYESGNTVFARWNYDKNLLSDEEGAKFQLLFQKMCIVDYVIRNTDRHMDNLLVR-------------------------HVPGEEINLAAIDNGLAFPVRHPECTSRFRSFPFRWSNLPWAQGEFDPVLRRHVLSLLTPQ-----FVHRLCVDLKKLFR---HGIASSNYMLVNSQLRVVRGQIWNLRQAILANESPGEMACRDPIIV 345
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Fly
Match: Pi4KIIalpha (gene:FBgn0037339 transcript:FBtr0078755)

HSP 1 Score: 193.356 bits (490), Expect = 2.269e-54
Identity = 104/218 (47.71%), Postives = 144/218 (66.06%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQS-RINSQL 900
            ++V  AE A +  + P  I QGSSGSYFV++ + + + VFKPKDEEPY   NPKW+K+ H+LCCPCCFGR CLI N GYLSE GAS++D  L LN+VP TR+ +L + +FN+  ++  K+K K  I E +P     F+R+ +P K GS Q+FV  Y+ A            P+   + + F  +F++LVVLDYIIRNTDR N NWLIK+ + +I +Q+
Sbjct:  124 EIVAKAEGAIENGVLPERIYQGSSGSYFVKDASHQCLAVFKPKDEEPYGRLNPKWTKWMHKLCCPCCFGRACLIPNQGYLSESGASLVDRKLNLNVVPKTRVVRLVAESFNYARIDRQKAKLKKRIKEHYPSA--HFNRMSLPLKTGSFQLFVEGYKDA--DYWLRRFESEPLPPSVAKSFQLQFERLVVLDYIIRNTDRGNDNWLIKYVAPKITTQV 337

HSP 2 Score: 134.035 bits (336), Expect = 3.065e-33
Identity = 61/114 (53.51%), Postives = 81/114 (71.05%), Query Frame = 1 
Query:  964 FIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            FI+IAAIDNGLAFP+KHPD  R YPY+W+WL  A +PF + I   +LP+L D  FVE++   L  LF+ +  F K +FE+QM+V+RGQI NL  ALR  K+P QLV+M  + +E
Sbjct:  426 FIRIAAIDNGLAFPFKHPDSWRAYPYHWAWLPQAKIPFSEEIKEQVLPQLSDMNFVEEICTELLYLFQQDRGFDKRLFERQMSVMRGQILNLTQALRDGKSPVQLVQMPAVIVE 539
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Fly
Match: Pi4KIIalpha (gene:FBgn0037339 transcript:FBtr0078757)

HSP 1 Score: 193.741 bits (491), Expect = 1.320e-53
Identity = 104/218 (47.71%), Postives = 144/218 (66.06%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQS-RINSQL 900
            ++V  AE A +  + P  I QGSSGSYFV++ + + + VFKPKDEEPY   NPKW+K+ H+LCCPCCFGR CLI N GYLSE GAS++D  L LN+VP TR+ +L + +FN+  ++  K+K K  I E +P     F+R+ +P K GS Q+FV  Y+ A            P+   + + F  +F++LVVLDYIIRNTDR N NWLIK+ + +I +Q+
Sbjct:  271 EIVAKAEGAIENGVLPERIYQGSSGSYFVKDASHQCLAVFKPKDEEPYGRLNPKWTKWMHKLCCPCCFGRACLIPNQGYLSESGASLVDRKLNLNVVPKTRVVRLVAESFNYARIDRQKAKLKKRIKEHYPSA--HFNRMSLPLKTGSFQLFVEGYKDA--DYWLRRFESEPLPPSVAKSFQLQFERLVVLDYIIRNTDRGNDNWLIKYVAPKITTQV 484

HSP 2 Score: 135.191 bits (339), Expect = 2.626e-33
Identity = 61/114 (53.51%), Postives = 81/114 (71.05%), Query Frame = 1 
Query:  964 FIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            FI+IAAIDNGLAFP+KHPD  R YPY+W+WL  A +PF + I   +LP+L D  FVE++   L  LF+ +  F K +FE+QM+V+RGQI NL  ALR  K+P QLV+M  + +E
Sbjct:  573 FIRIAAIDNGLAFPFKHPDSWRAYPYHWAWLPQAKIPFSEEIKEQVLPQLSDMNFVEEICTELLYLFQQDRGFDKRLFERQMSVMRGQILNLTQALRDGKSPVQLVQMPAVIVE 686
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Fly
Match: Pi4KIIalpha (gene:FBgn0037339 transcript:FBtr0078756)

HSP 1 Score: 193.741 bits (491), Expect = 1.320e-53
Identity = 104/218 (47.71%), Postives = 144/218 (66.06%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQS-RINSQL 900
            ++V  AE A +  + P  I QGSSGSYFV++ + + + VFKPKDEEPY   NPKW+K+ H+LCCPCCFGR CLI N GYLSE GAS++D  L LN+VP TR+ +L + +FN+  ++  K+K K  I E +P     F+R+ +P K GS Q+FV  Y+ A            P+   + + F  +F++LVVLDYIIRNTDR N NWLIK+ + +I +Q+
Sbjct:  271 EIVAKAEGAIENGVLPERIYQGSSGSYFVKDASHQCLAVFKPKDEEPYGRLNPKWTKWMHKLCCPCCFGRACLIPNQGYLSESGASLVDRKLNLNVVPKTRVVRLVAESFNYARIDRQKAKLKKRIKEHYPSA--HFNRMSLPLKTGSFQLFVEGYKDA--DYWLRRFESEPLPPSVAKSFQLQFERLVVLDYIIRNTDRGNDNWLIKYVAPKITTQV 484

HSP 2 Score: 135.191 bits (339), Expect = 2.626e-33
Identity = 61/114 (53.51%), Postives = 81/114 (71.05%), Query Frame = 1 
Query:  964 FIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            FI+IAAIDNGLAFP+KHPD  R YPY+W+WL  A +PF + I   +LP+L D  FVE++   L  LF+ +  F K +FE+QM+V+RGQI NL  ALR  K+P QLV+M  + +E
Sbjct:  573 FIRIAAIDNGLAFPFKHPDSWRAYPYHWAWLPQAKIPFSEEIKEQVLPQLSDMNFVEEICTELLYLFQQDRGFDKRLFERQMSVMRGQILNLTQALRDGKSPVQLVQMPAVIVE 686
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Zebrafish
Match: pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:NCBI gene;Acc:406667])

HSP 1 Score: 328.561 bits (841), Expect = 5.313e-107
Identity = 180/409 (44.01%), Postives = 246/409 (60.15%), Query Frame = 1 
Query:  172 SDENYRLVQNDLSDKNRDLFLHSTIED-----VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRK 1383
            S E   L+  D     RD   +   ED     ++  AE A ++ I P  I QGSSGSYFV++   +IIGVFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++FHR+G+PPK GS QIFV  Y+ A            P+      +   +F++LVVLDYIIRNTDR N NWLIK+   +++    D +              +  IK+AAIDNGLAFP KHPD  R YP+YW+WL  A V F   I  L+LPKL D  F++ + ++L  LFK +  F +  F+KQ++V+RGQI NL  A+R  KTP QLV+M P+ +E        VP    S + +    +R+
Sbjct:   49 SRERQPLLDRDRGASPRDPHRNEFPEDPEFREIIRKAERAIEEGIYPERIYQGSSGSYFVKDSAGKIIGVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFHRIGLPPKVGSFQIFVEGYKDA--DFWLRRFEAEPLPENTNRQLQLQFERLVVLDYIIRNTDRGNDNWLIKYDYPMDTSSNRDSD---------WVLVKDPIIKLAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVVFSQEIRDLVLPKLADPNFIKDLEEDLYELFKKDPGFDRGQFKKQVSVMRGQILNLSQAMRDGKTPLQLVQMPPVIVETAR-----VPQRANSESYTQSFQSRR 441
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Zebrafish
Match: pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:NCBI gene;Acc:406667])

HSP 1 Score: 328.561 bits (841), Expect = 5.313e-107
Identity = 180/409 (44.01%), Postives = 246/409 (60.15%), Query Frame = 1 
Query:  172 SDENYRLVQNDLSDKNRDLFLHSTIED-----VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRK 1383
            S E   L+  D     RD   +   ED     ++  AE A ++ I P  I QGSSGSYFV++   +IIGVFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++FHR+G+PPK GS QIFV  Y+ A            P+      +   +F++LVVLDYIIRNTDR N NWLIK+   +++    D +              +  IK+AAIDNGLAFP KHPD  R YP+YW+WL  A V F   I  L+LPKL D  F++ + ++L  LFK +  F +  F+KQ++V+RGQI NL  A+R  KTP QLV+M P+ +E        VP    S + +    +R+
Sbjct:   49 SRERQPLLDRDRGASPRDPHRNEFPEDPEFREIIRKAERAIEEGIYPERIYQGSSGSYFVKDSAGKIIGVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFHRIGLPPKVGSFQIFVEGYKDA--DFWLRRFEAEPLPENTNRQLQLQFERLVVLDYIIRNTDRGNDNWLIKYDYPMDTSSNRDSD---------WVLVKDPIIKLAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVVFSQEIRDLVLPKLADPNFIKDLEEDLYELFKKDPGFDRGQFKKQVSVMRGQILNLSQAMRDGKTPLQLVQMPPVIVETAR-----VPQRANSESYTQSFQSRR 441
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Zebrafish
Match: pi4k2b (phosphatidylinositol 4-kinase type 2 beta [Source:NCBI gene;Acc:564750])

HSP 1 Score: 327.02 bits (837), Expect = 9.034e-106
Identity = 175/396 (44.19%), Postives = 247/396 (62.37%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTK--YWKRPFF 1431
            +++  AE A +  + P  I QGSSGSYFV++   +IIGVFKPK EEPY   NPKW+KYFH++CCPCCFGR CLI N GYLSE  AS++D+ L L IVP T++  L S  F++N ++  KS+ K +  E  P +GR+FHR+G+PPK GS Q+FV  Y  A            P+   ++++   +F++LVVLDY+IRNTDR N NWLIK++   + +L +          ++     +S IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A V F      L+L ++ D  FV+ + ++L  +F+ +  F K++FEKQM+V+RGQI NL  AL+  K+P QLV+M  + +             ERSR+       R  Q+ N  T+  + KRPFF
Sbjct:  129 EIIQRAEQAIENGVFPERISQGSSGSYFVKDPKGKIIGVFKPKSEEPYGHLNPKWTKYFHKVCCPCCFGRGCLIPNQGYLSEAAASLVDQKLGLWIVPKTKVVHLASETFHYNAIDRAKSRGKKYALEKVPKVGRRFHRVGLPPKVGSFQLFVEGYHEA--DFWLRKFEAEPLPENMRKQLQSQFERLVVLDYVIRNTDRGNDNWLIKYEKPGDGELTE--------KESEWTDPKDSAIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVAFSQETRDLVLSRISDMNFVQDLCEDLYEMFRTDKGFDKTMFEKQMSVMRGQILNLTQALKDGKSPIQLVQMPRVVV-------------ERSRSG---GQGRVVQLGNAFTQTFHCKRPFF 498
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Xenopus
Match: dtx4 (Xenopus tropicalis phosphatidylinositol 4-kinase type 2 beta (pi4k2b), mRNA. [Source:RefSeq mRNA;Acc:NM_001016953])

HSP 1 Score: 343.969 bits (881), Expect = 3.057e-112
Identity = 171/352 (48.58%), Postives = 231/352 (65.62%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            D++H AE A +  + P  I QGSSGSYFV++   +IIGVFKPK EEPY   NPKW+KYFH++CCPCCFGR CL+ N GYLSE GA ++DE L L +VP T++  L S  FN++ ++  KS+ K +  E  P +GRKFHR+G+PPK GS Q+FV  Y+ A            P+    +++   +F+KLV+LDY+IRNTDR N NWLI++ S+   +L   +  GD              IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A VPF      L+LP++ D  FV+ + ++L  LFK +  F K+ FEKQM+V+RGQI NL  AL+  KTP QLV+M  + +E
Sbjct:  115 DIIHRAEQAIESGVFPERISQGSSGSYFVKDPKGKIIGVFKPKSEEPYGHLNPKWTKYFHKICCPCCFGRGCLVPNQGYLSEAGAYLVDEKLGLGVVPKTKVVWLVSETFNYSAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKVGSFQLFVDGYKEA--DYWLRKFETDPLPENTRKQLQCQFEKLVILDYVIRNTDRGNDNWLIRYDSQDEDEL---MEKGDDFPLKDWKEIKEPVIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSQETRDLILPRISDMNFVQDLCEDLYELFKTDKGFDKATFEKQMSVMRGQILNLTQALKDGKTPIQLVQMPRVVVE 461
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Xenopus
Match: dtx4 (Xenopus tropicalis phosphatidylinositol 4-kinase type 2 beta (pi4k2b), mRNA. [Source:RefSeq mRNA;Acc:NM_001016953])

HSP 1 Score: 340.887 bits (873), Expect = 1.682e-110
Identity = 171/352 (48.58%), Postives = 231/352 (65.62%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            D++H AE A +  + P  I QGSSGSYFV++   +IIGVFKPK EEPY   NPKW+KYFH++CCPCCFGR CL+ N GYLSE GA ++DE L L +VP T++  L S  FN++ ++  KS+ K +  E  P +GRKFHR+G+PPK GS Q+FV  Y+ A            P+    +++   +F+KLV+LDY+IRNTDR N NWLI++ S+   +L   +  GD              IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A VPF      L+LP++ D  FV+ + ++L  LFK +  F K+ FEKQM+V+RGQI NL  AL+  KTP QLV+M  + +E
Sbjct:  160 DIIHRAEQAIESGVFPERISQGSSGSYFVKDPKGKIIGVFKPKSEEPYGHLNPKWTKYFHKICCPCCFGRGCLVPNQGYLSEAGAYLVDEKLGLGVVPKTKVVWLVSETFNYSAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKVGSFQLFVDGYKEA--DYWLRKFETDPLPENTRKQLQCQFEKLVILDYVIRNTDRGNDNWLIRYDSQDEDEL---MEKGDDFPLKDWKEIKEPVIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSQETRDLILPRISDMNFVQDLCEDLYELFKTDKGFDKATFEKQMSVMRGQILNLTQALKDGKTPIQLVQMPRVVVE 506
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Xenopus
Match: pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:NCBI gene;Acc:594904])

HSP 1 Score: 324.709 bits (831), Expect = 2.988e-105
Identity = 172/357 (48.18%), Postives = 227/357 (63.59%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINS-QLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINS 1317
            +VV  AE A  +DI P  I QGSSGSYFV+N   EII VFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++F+R+G+PPK GS Q+FV  Y+ A            P+      +   +F++LVVLDYIIRNTDR N NWLIK+   ++S   +DD                   IKIAAIDNGLAFP KHPD  R YP+YW+WL  A + F   I  L+LPK+ D  FV+ + ++L  LFK +  F +  F KQ+AV+RGQI NL  AL+  K+P QLV+  P+ +E   S
Sbjct:   91 EVVKKAEKAIVRDILPERISQGSSGSYFVKNEQGEIIAVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVFLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVKGYKDA--DYWLRRFEADPLPENTNRQLQLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDSASARDDW-----------VMVKEPVIKIAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKIQFSQEIKDLILPKISDPNFVKDLEEDLYELFKRDPGFDRGQFRKQIAVMRGQILNLTQALKDGKSPLQLVQTPPVIVETARS 434
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Xenopus
Match: pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:NCBI gene;Acc:594904])

HSP 1 Score: 323.553 bits (828), Expect = 1.343e-104
Identity = 171/356 (48.03%), Postives = 227/356 (63.76%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINS 1317
            +VV  AE A  +DI P  I QGSSGSYFV+N   EII VFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++F+R+G+PPK GS Q+FV  Y+ A            P+      +   +F++LVVLDYIIRNTDR N NWLIK+   ++S       A    + +         IKIAAIDNGLAFP KHPD  R YP+YW+WL  A + F   I  L+LPK+ D  FV+ + ++L  LFK +  F +  F KQ+AV+RGQI NL  AL+  K+P QLV+  P+ +E   S
Sbjct:  105 EVVKKAEKAIVRDILPERISQGSSGSYFVKNEQGEIIAVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVFLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVKGYKDA--DYWLRRFEADPLPENTNRQLQLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDS-------ASARVSFDDWVMVKEPVIKIAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKIQFSQEIKDLILPKISDPNFVKDLEEDLYELFKRDPGFDRGQFRKQIAVMRGQILNLTQALKDGKSPLQLVQTPPVIVETARS 451
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Xenopus
Match: pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:NCBI gene;Acc:594904])

HSP 1 Score: 296.975 bits (759), Expect = 2.020e-94
Identity = 168/360 (46.67%), Postives = 220/360 (61.11%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINS-QLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRG---QITNLCAALRQKKTPAQLVEMAPMTLELINS 1317
            +VV  AE A  +DI P  I QGSSGSYFV+N   EII VFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++F+R+G+PPK GS Q+FV  Y+ A            P+      +   +F++LVVLDYIIRNTDR N NWLIK+   ++S   +DD                   IKIAAIDNGLAFP KHPD  R YP+YW+WL  A + F   I  L+LPK+ D  FV+ + ++L  LFK        VF  Q + L     QI NL  AL+  K+P QLV+  P+ +E   S
Sbjct:  105 EVVKKAEKAIVRDILPERISQGSSGSYFVKNEQGEIIAVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVFLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVKGYKDA--DYWLRRFEADPLPENTNRQLQLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDSASARDDW-----------VMVKEPVIKIAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKIQFSQEIKDLILPKISDPNFVKDLEEDLYELFK--------VFVCQCSNLMPPPIQILNLTQALKDGKSPLQLVQTPPVIVETARS 443
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Mouse
Match: Pi4k2b (phosphatidylinositol 4-kinase type 2 beta [Source:MGI Symbol;Acc:MGI:1914323])

HSP 1 Score: 325.865 bits (834), Expect = 1.123e-105
Identity = 169/361 (46.81%), Postives = 231/361 (63.99%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQS-----RINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINS 1317
            D+V  AE A +  + P  I QGSSGSYFV++  + IIGVFKPK EEPY   NPKW+KY H++CCPCCFGR CL+ N GYLSE GA ++D  L L IVP T++  L S  FN++ ++  KS+ K +  E  P +GRKFHR+G+PPK GS Q+FV DY+ A            P+   ++++F  +F+KLV+LDYIIRNTDR N NWL+K+       +I S+  + ++   +             IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A VPF +    L+LP + D  FV+ + ++L  LFK +  F ++ FE QM+V+RGQI NL  ALR  K+P QL +M  + +E   S
Sbjct:   96 DIVLKAEQAIEIGVFPERISQGSSGSYFVKDSKRNIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCLLPNQGYLSEAGAYLVDVKLNLGIVPKTKVVWLVSETFNYSAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKVGSFQLFVKDYKEA--EYWLRRFEAEPLPENIRKQFQSQFEKLVILDYIIRNTDRGNDNWLVKYDEMKYAKKIESEESNWIDNKQL------------LIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSEETRNLILPYISDMNFVQDLCEDLYELFKTDKGFDRAAFENQMSVMRGQILNLTQALRDGKSPMQLAQMPCVIVECSKS 442
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Mouse
Match: Pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:MGI Symbol;Acc:MGI:1934031])

HSP 1 Score: 320.857 bits (821), Expect = 1.326e-103
Identity = 170/359 (47.35%), Postives = 227/359 (63.23%), Query Frame = 1 
Query:  244 IEDVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRI-NSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINS 1317
             E VV  AE+A +  I P  I QGSSGSYFV++    I+ VFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++F+R+G+PPK GS Q+FV  Y+ A            P+      + L +F++LVVLDYIIRNTDR N NWLIK+   + NS  +D                    IK+AAIDNGLAFP KHPD  R YP+YW+WL  A VPF   I  L+LPK+ D  F++ + ++L  LFK +  F +  F KQ+AV+RGQI NL  AL+  K+P  LV+M P+ +E   S
Sbjct:  110 FEVVVRQAEVAIECSIYPERIYQGSSGSYFVKDSQGRIVAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVEGYKDA--DYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDNSSCRD----------TDWVMVREPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFIKDLEEDLYELFKRDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARS 456
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Mouse
Match: Pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:MGI Symbol;Acc:MGI:1934031])

HSP 1 Score: 320.857 bits (821), Expect = 1.326e-103
Identity = 170/359 (47.35%), Postives = 227/359 (63.23%), Query Frame = 1 
Query:  244 IEDVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRI-NSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINS 1317
             E VV  AE+A +  I P  I QGSSGSYFV++    I+ VFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++F+R+G+PPK GS Q+FV  Y+ A            P+      + L +F++LVVLDYIIRNTDR N NWLIK+   + NS  +D                    IK+AAIDNGLAFP KHPD  R YP+YW+WL  A VPF   I  L+LPK+ D  F++ + ++L  LFK +  F +  F KQ+AV+RGQI NL  AL+  K+P  LV+M P+ +E   S
Sbjct:  110 FEVVVRQAEVAIECSIYPERIYQGSSGSYFVKDSQGRIVAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVEGYKDA--DYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDNSSCRD----------TDWVMVREPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFIKDLEEDLYELFKRDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARS 456
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Mouse
Match: Pi4k2b (phosphatidylinositol 4-kinase type 2 beta [Source:MGI Symbol;Acc:MGI:1914323])

HSP 1 Score: 296.59 bits (758), Expect = 1.136e-94
Identity = 153/326 (46.93%), Postives = 209/326 (64.11%), Query Frame = 1 
Query:  355 IIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQS-----RINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINS 1317
            IIGVFKPK EEPY   NPKW+KY H++CCPCCFGR CL+ N GYLSE GA ++D  L L IVP T++  L S  FN++ ++  KS+ K +  E  P +GRKFHR+G+PPK GS Q+FV DY+ A            P+   ++++F  +F+KLV+LDYIIRNTDR N NWL+K+       +I S+  + ++   +             IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A VPF +    L+LP + D  FV+ + ++L  LFK +  F ++ FE QM+V+RGQI NL  ALR  K+P QL +M  + +E   S
Sbjct:  108 IIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCLLPNQGYLSEAGAYLVDVKLNLGIVPKTKVVWLVSETFNYSAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKVGSFQLFVKDYKEA--EYWLRRFEAEPLPENIRKQFQSQFEKLVILDYIIRNTDRGNDNWLVKYDEMKYAKKIESEESNWIDNKQL------------LIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSEETRNLILPYISDMNFVQDLCEDLYELFKTDKGFDRAAFENQMSVMRGQILNLTQALRDGKSPMQLAQMPCVIVECSKS 419
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Mouse
Match: Pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:MGI Symbol;Acc:MGI:1934031])

HSP 1 Score: 235.728 bits (600), Expect = 6.921e-72
Identity = 132/287 (45.99%), Postives = 176/287 (61.32%), Query Frame = 1 
Query:  244 IEDVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRI-NSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLL 1101
             E VV  AE+A +  I P  I QGSSGSYFV++    I+ VFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++F+R+G+PPK GS Q+FV  Y+ A            P+      + L +F++LVVLDYIIRNTDR N NWLIK+   + NS  +D                    IK+AAIDNGLAFP KHPD  R   +  +   + SV  C R+ L +
Sbjct:  110 FEVVVRQAEVAIECSIYPERIYQGSSGSYFVKDSQGRIVAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVEGYKDA--DYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDNSSCRD----------TDWVMVREPVIKVAAIDNGLAFPLKHPDSWRACKFKST--GLCSVRCCSRVGLRI 382
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. UniProt/SwissProt
Match: sp|Q28G26|P4K2B_XENTR (Phosphatidylinositol 4-kinase type 2-beta OS=Xenopus tropicalis OX=8364 GN=pi4k2b PE=2 SV=1)

HSP 1 Score: 344.354 bits (882), Expect = 9.553e-112
Identity = 171/352 (48.58%), Postives = 232/352 (65.91%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            D++H AE A +  + P  I QGSSGSYFV++   +IIGVFKPK EEPY   NPKW+KYFH++CCPCCFGR CL+ N GYLSE GA ++DE L L +VP T++  L S  FN++ ++  KS+ K +  E  P +GRKFHR+G+PPK GS Q+FV  Y+ A            P+    +++   +F+KLV+LDY+IRNTDR N NWLI++ S+ + +L   +  GD              IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A VPF      L+LP++ D  FV+ + ++L  LFK +  F K+ FEKQM+V+RGQI NL  AL+  KTP QLV+M  + +E
Sbjct:  115 DIIHRAEQAIESGVFPERISQGSSGSYFVKDPKGKIIGVFKPKSEEPYGHLNPKWTKYFHKICCPCCFGRGCLVPNQGYLSEAGAYLVDEKLGLGVVPKTKVVWLVSETFNYSAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKVGSFQLFVDGYKEA--DYWLRKFETDPLPENTRKQLQCQFEKLVILDYVIRNTDRGNDNWLIRYDSQDDDEL---MEKGDDFPLKDWKEIKEPVIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSQETRDLILPRISDMNFVQDLCEDLYELFKTDKGFDKATFEKQMSVMRGQILNLTQALKDGKTPIQLVQMPRVVVE 461
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. UniProt/SwissProt
Match: sp|Q6DCQ8|P4K2B_XENLA (Phosphatidylinositol 4-kinase type 2-beta OS=Xenopus laevis OX=8355 GN=pi4k2b PE=2 SV=1)

HSP 1 Score: 341.273 bits (874), Expect = 1.595e-110
Identity = 169/352 (48.01%), Postives = 229/352 (65.06%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            D++H AE A +  + P  I QGSSGSYFV++   +IIGVFKPK EEPY   NPKW+KYFH++CCPCCFGR CL+ N GYLSE GA ++DE L L +VP T+   L S  FN++ ++  KS+ K +  E  P +G+KFHR+G+PPK GS Q+FV  Y+ A            P+    +++    F+KLV+LDY+IRNTDR N NWLI++ S+ + +L +    GD              IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A VPF      L+LP++ D  F++ + ++L  LFK +  F K  FEKQM+V+RGQI NL  AL+  KTP QLV+M  + +E
Sbjct:  118 DIIHRAEQAIESGVFPERISQGSSGSYFVKDPKGKIIGVFKPKSEEPYGHLNPKWTKYFHKICCPCCFGRGCLVPNQGYLSEAGAYLVDEKLGLGVVPKTKAVWLVSETFNYSAIDRAKSRGKKYALEKVPKVGKKFHRIGLPPKVGSFQLFVDGYKEA--DYWLRKFETDPLPENTRKQLQSPFEKLVILDYVIRNTDRGNDNWLIRYDSQDDDELSE---KGDSFPLKDWKEIKEPIIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSQETRDLILPRISDMNFIQDLCEDLYELFKTDKGFDKDTFEKQMSVMRGQILNLTQALKDGKTPIQLVQMPRVVVE 464
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. UniProt/SwissProt
Match: sp|Q6PE18|P4K2A_DANRE (Phosphatidylinositol 4-kinase type 2-alpha OS=Danio rerio OX=7955 GN=pi4k2a PE=2 SV=1)

HSP 1 Score: 328.561 bits (841), Expect = 4.010e-106
Identity = 180/409 (44.01%), Postives = 246/409 (60.15%), Query Frame = 1 
Query:  172 SDENYRLVQNDLSDKNRDLFLHSTIED-----VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRK 1383
            S E   L+  D     RD   +   ED     ++  AE A ++ I P  I QGSSGSYFV++   +IIGVFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++FHR+G+PPK GS QIFV  Y+ A            P+      +   +F++LVVLDYIIRNTDR N NWLIK+   +++    D +              +  IK+AAIDNGLAFP KHPD  R YP+YW+WL  A V F   I  L+LPKL D  F++ + ++L  LFK +  F +  F+KQ++V+RGQI NL  A+R  KTP QLV+M P+ +E        VP    S + +    +R+
Sbjct:   49 SRERQPLLDRDRGASPRDPHRNEFPEDPEFREIIRKAERAIEEGIYPERIYQGSSGSYFVKDSAGKIIGVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFHRIGLPPKVGSFQIFVEGYKDA--DFWLRRFEAEPLPENTNRQLQLQFERLVVLDYIIRNTDRGNDNWLIKYDYPMDTSSNRDSD---------WVLVKDPIIKLAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVVFSQEIRDLVLPKLADPNFIKDLEEDLYELFKKDPGFDRGQFKKQVSVMRGQILNLSQAMRDGKTPLQLVQMPPVIVETAR-----VPQRANSESYTQSFQSRR 441
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. UniProt/SwissProt
Match: sp|Q8TCG2|P4K2B_HUMAN (Phosphatidylinositol 4-kinase type 2-beta OS=Homo sapiens OX=9606 GN=PI4K2B PE=1 SV=1)

HSP 1 Score: 327.405 bits (838), Expect = 2.970e-105
Identity = 169/352 (48.01%), Postives = 231/352 (65.62%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            D++  AE A +  I P  I QGSSGSYFV++  ++IIGVFKPK EEPY   NPKW+KY H++CCPCCFGR CLI N GYLSE GA ++D  L L+IVP T++  L S  FN+N ++  KS+ K +  E  P +GRKFHR+G+PPK GS Q+FV  Y+ A            P+   ++++F  +F++LV+LDYIIRNTDR N NWL++++ +   +  D   +  I             IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A VPF + I  L+LP + D  FV+ + ++L  LFK +  F K+ FE QM+V+RGQI NL  ALR  K+P QLV++  + +E
Sbjct:  108 DIMLRAEQAIEVGIFPERISQGSSGSYFVKDPKRKIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCLIPNQGYLSEAGAYLVDNKLHLSIVPKTKVVWLVSETFNYNAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKIGSFQLFVEGYKEA--EYWLRKFEADPLPENIRKQFQSQFERLVILDYIIRNTDRGNDNWLVRYEKQKCEKEIDHKESKWI-------DDEEFLIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSEEIRNLILPYISDMNFVQDLCEDLYELFKTDKGFDKATFESQMSVMRGQILNLTQALRDGKSPFQLVQIPCVIVE 450
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. UniProt/SwissProt
Match: sp|Q5XIL2|P4K2B_RAT (Phosphatidylinositol 4-kinase type 2-beta OS=Rattus norvegicus OX=10116 GN=Pi4k2b PE=2 SV=1)

HSP 1 Score: 327.02 bits (837), Expect = 3.266e-105
Identity = 168/361 (46.54%), Postives = 232/361 (64.27%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQS-----RINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINS 1317
            DVV  AE A +  + P  I QGSSGSYFV++  + IIGVFKPK EEPY   NPKW+KY H++CCPCCFGR CL+ N GYLSE GA ++D  L+L IVP T++  L S  FN++ ++  KS+ K +  E  P +GRKFHR+G+PPK GS Q+FV DY+ A            P+   ++++F  +F++LV+LDYIIRNTDR N NWL+K+       +I S+  + ++   +             I+IAAIDNGLAFP+KHPD+ R YP++W+WL  A VPF +    L+LP + D  FV+ + ++L  LFK +  F ++ FE QM+V+RGQI NL  ALR  K+P QL +M  + +E   S
Sbjct:  104 DVVLKAEQAIEIGVFPERISQGSSGSYFVKDSKRTIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCLLPNQGYLSEAGAYLVDTKLQLGIVPKTKVVWLVSETFNYSAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKIGSFQLFVKDYKEA--EYWLRRFEAEPLPENIRKQFQSQFERLVILDYIIRNTDRGNDNWLVKYDEMKYAKKIESEESNWIDDKQL------------LIRIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSEETRNLILPFISDMNFVQDLCEDLYELFKTDKGFDRAAFESQMSVMRGQILNLTQALRDGKSPMQLAQMPCVIVECSKS 450
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. TrEMBL
Match: A0A1S3IMP5 (phosphatidylinositol 4-kinase type 2-beta isoform X2 OS=Lingula unguis OX=7574 GN=LOC106165704 PE=4 SV=1)

HSP 1 Score: 362.844 bits (930), Expect = 6.564e-117
Identity = 191/394 (48.48%), Postives = 257/394 (65.23%), Query Frame = 1 
Query:  253 VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTKYWKR-PFF 1431
            ++  AE   D  + P  I QGSSGSYFV+N + +I+GVFKPKDEEPY   NPKW+K+ H+LCCPCCFGR CL+ N GYLSE GASI+D+ L+LN+VP T++ +L S  FN++ ++  KS+TK +I E FP+LGR FHR+G+PPK GS Q+FV +Y+ A+  +    N  LP      + F  +F+KLVVLDYIIRNTDR N NWLIK++    S++ D+ + GD  +           I +AAIDNGLAFP+KHPD+ R YPY+W+WL +A  PF + +  L+LP+L D  FVE + D L LLFK +  F K  FEKQM+V+RGQI NL  ALR  K+P QLV+M  +T+             ERS++       R      ++ ++ KR PFF
Sbjct:   74 IIRQAEQTIDAGVFPERISQGSSGSYFVKNTDGKILGVFKPKDEEPYGKLNPKWTKWMHKLCCPCCFGRSCLVPNQGYLSEAGASIVDQKLQLNVVPKTKVVRLASETFNYSAIDRAKSRTKRNIQERFPELGRHFHRIGLPPKSGSFQLFVENYKDADFWLRRFDNEALP--ESTAKSFQLQFEKLVVLDYIIRNTDRGNDNWLIKYE---KSEV-DESSGGDEDDDVDWSMVKPPEISVAAIDNGLAFPFKHPDEWRAYPYHWAWLPMAKKPFSEELKSLVLPQLSDMTFVEDLCDELYLLFKTDKGFDKRTFEKQMSVMRGQILNLSQALRDGKSPVQLVQMPVVTV-------------ERSKSGYGPGRPRTASGETFIQRFSKRAPFF 448
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. TrEMBL
Match: A0A443QFU5 (Phosphatidylinositol 4-kinase type 2-alpha-like isoform X1 OS=Dinothrombium tinctorium OX=1965070 GN=B4U79_09148 PE=4 SV=1)

HSP 1 Score: 353.599 bits (906), Expect = 2.987e-113
Identity = 187/353 (52.97%), Postives = 245/353 (69.41%), Query Frame = 1 
Query:  253 VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQ--EIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            ++  AE A D  I P  I QGSSGSYFVRN ++  +IIGVFKPKDEEPY   NPKW+K+ H+LCCPCCFGR CL+ N GYLSE GAS++D  L+LNIVP TR+ +L S  FN++ ++  KSKTK ++++ FP +GR+FHR+G+PPK GS Q FV  YE A   +    +  LP D  +Q+EF  +F++LV+LDYIIRNTDRNN NWLIK+       +K+  N    +  N    +    IKIAAIDNGLAFP+KHPD+ R YPYYW+WL  A +PF + I  L+LP L D  FV+++ D L  LFK +  F + +FEKQM+V+RGQI NL  AL++ KTP QLV+M  + +E
Sbjct:   84 LIREAENAIDNGIYPERISQGSSGSYFVRNSDEIPKIIGVFKPKDEEPYGRLNPKWTKWMHKLCCPCCFGRSCLVPNQGYLSEAGASLVDRKLQLNIVPKTRVVKLVSKTFNYSAIDRAKSKTKQNVSDRFPSVGRRFHRIGLPPKTGSFQQFVEGYEDAYVWLRRFEDEPLPDD--VQKEFQSQFERLVILDYIIRNTDRNNDNWLIKY-------VKEPSNN---SPSNTWSPKKQPLIKIAAIDNGLAFPFKHPDEWRAYPYYWAWLPYAKIPFSNEIKELVLPTLSDMNFVQELCDELYDLFKTDKGFDRHLFEKQMSVMRGQILNLTQALKEGKTPLQLVQMPSVLVE 424
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. TrEMBL
Match: R7UKK8 (PI3K/PI4K domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_152761 PE=4 SV=1)

HSP 1 Score: 352.443 bits (903), Expect = 3.374e-113
Identity = 186/380 (48.95%), Postives = 254/380 (66.84%), Query Frame = 1 
Query:  253 VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQ--LKDDLNAGDIAXXXXX-XXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRK 1383
            +++  ELA ++ + P +I  GSSGSY++R+ N + IGVFKPKDEEPY   NPKW+K+ H+LCCPCCFGR CL+ N GYLSE GAS++D  L+LN+VP T++ +L+S  FN+N ++  KS+TK ++AE FP++GRKFHRLG+PPK GS Q+FVS+++ A            P+    Q +F+ +F++LVVLDYIIRNTDR N NWLI+      S+   + D+   D+A+         +  I IAAIDNGLAFPYKHPD+ R YPY+W+WL  A VPF   I  L+LP+L D  FV+ + D L  LFK +  F K  F+KQM+V+RGQI NL  AL+  K+P QLV+M  + +E  + T        R RT S+D  T+K
Sbjct:   52 LINETELAIEEGVRPELIKAGSSGSYWIRSRNAKTIGVFKPKDEEPYGHLNPKWTKWMHKLCCPCCFGRSCLVPNQGYLSEAGASLVDLKLQLNVVPKTKVVRLSSDTFNYNAIDRAKSRTKRNVAERFPEIGRKFHRLGLPPKTGSFQLFVSEFKDA--DFWLRKFESEPLPESTQRQFMHQFERLVVLDYIIRNTDRGNDNWLIRLDKPDISEEDAETDVIIPDLASPGDDWSLVKHPEISIAAIDNGLAFPYKHPDEWRAYPYHWAWLPQAKVPFSQEIKELVLPQLSDMNFVQDLCDELYELFKTDKGFDKHTFDKQMSVMRGQILNLTQALKDGKSPVQLVQMPVVVVERSHKTY----GKGRQRTTSSDTFTQK 425
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. TrEMBL
Match: A0A1S3INJ5 (phosphatidylinositol 4-kinase type 2-alpha isoform X1 OS=Lingula unguis OX=7574 GN=LOC106165704 PE=4 SV=1)

HSP 1 Score: 353.214 bits (905), Expect = 4.932e-113
Identity = 191/404 (47.28%), Postives = 261/404 (64.60%), Query Frame = 1 
Query:  253 VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXF----------IKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTKYWKR-PFF 1431
            ++  AE   D  + P  I QGSSGSYFV+N + +I+GVFKPKDEEPY   NPKW+K+ H+LCCPCCFGR CL+ N GYLSE GASI+D+ L+LN+VP T++ +L S  FN++ ++  KS+TK +I E FP+LGR FHR+G+PPK GS Q+FV +Y+ A+  +    N  LP  +   + F  +F+KLVVLDYIIRNTDR N NWLIK++    S++ D+ + GD  + + +   ++            I++ AIDNGLAFPYKHPD  R YPY+W+WL +A  PF + +  L+LP+L D  FVE + D L LLFK +  F K  FEKQM+V+RGQI NL  ALR  K+P QLV+M  +T+             ERS++       R      ++ ++ KR PFF
Sbjct:   74 IIRQAEQTIDAGVFPERISQGSSGSYFVKNTDGKILGVFKPKDEEPYGKLNPKWTKWMHKLCCPCCFGRSCLVPNQGYLSEAGASIVDQKLQLNVVPKTKVVRLASETFNYSAIDRAKSRTKRNIQERFPELGRHFHRIGLPPKSGSFQLFVENYKDADFWLRRFDNEALPEST--AKSFQLQFEKLVVLDYIIRNTDRGNDNWLIKYE---KSEV-DESSGGDEDDADDEDDDDDDEMDWGMVKPPSIQVKAIDNGLAFPYKHPDSWRAYPYHWAWLPMAKKPFSEELKSLVLPQLSDMTFVEDLCDELYLLFKTDKGFDKRTFEKQMSVMRGQILNLSQALRDGKSPVQLVQMPVVTV-------------ERSKSGYGPGRPRTASGETFIQRFSKRAPFF 458
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. TrEMBL
Match: A0A1S3IN12 (phosphatidylinositol 4-kinase type 2-beta isoform X3 OS=Lingula unguis OX=7574 GN=LOC106165704 PE=4 SV=1)

HSP 1 Score: 348.977 bits (894), Expect = 8.259e-112
Identity = 192/416 (46.15%), Postives = 264/416 (63.46%), Query Frame = 1 
Query:  217 NRDLFLHSTIEDVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXF----------IKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTKYWKR-PFF 1431
            + DL     I DV    E A ++ + P +I  GSSGSYF+++   +I+GVFKPKDEEPY   NPKW+K+ H+LCCPCCFGR CL+ N GYLSE GASI+D+ L+LN+VP T++ +L S  FN++ ++  KS+TK +I E FP+LGR FHR+G+PPK GS Q+FV +Y+ A+  +    N  LP      + F  +F+KLVVLDYIIRNTDR N NWLIK++    S++ D+ + GD  + + +   ++            I++ AIDNGLAFPYKHPD  R YPY+W+WL +A  PF + +  L+LP+L D  FVE + D L LLFK +  F K  FEKQM+V+RGQI NL  ALR  K+P QLV+M  +T+             ERS++       R      ++ ++ KR PFF
Sbjct:   40 DNDLEFSQVIRDV----EFAIEEGVLPELITSGSSGSYFIKDRTGKILGVFKPKDEEPYGKLNPKWTKWMHKLCCPCCFGRSCLVPNQGYLSEAGASIVDQKLQLNVVPKTKVVRLASETFNYSAIDRAKSRTKRNIQERFPELGRHFHRIGLPPKSGSFQLFVENYKDADFWLRRFDNEALP--ESTAKSFQLQFEKLVVLDYIIRNTDRGNDNWLIKYE---KSEV-DESSGGDEDDADDEDDDDDDEMDWGMVKPPSIQVKAIDNGLAFPYKHPDSWRAYPYHWAWLPMAKKPFSEELKSLVLPQLSDMTFVEDLCDELYLLFKTDKGFDKRTFEKQMSVMRGQILNLSQALRDGKSPVQLVQMPVVTV-------------ERSKSGYGPGRPRTASGETFIQRFSKRAPFF 432
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Cavefish
Match: pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:NCBI gene;Acc:103023819])

HSP 1 Score: 336.265 bits (861), Expect = 4.010e-110
Identity = 179/381 (46.98%), Postives = 238/381 (62.47%), Query Frame = 1 
Query:  178 ENYRLVQNDLSDKNRDLFLHSTIED-----VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            E   L+  D     RD   +   ED     +V  AE A D+ I P  I QGSSGSYFV++   +IIGVFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP TR+  L S  FN++ ++ +KS+ K    E  P +G++FHR+G+PPK GS Q+FV  Y+ A            P+      +   +F++LVVLDYIIRNTDR N NWLIK+   +++    D +              +  IKIAAIDNGLAFP KHPD  R YP+YW+WL+ A VPF   I  L+LPKL D  F++ + ++L  LFK +  F +  F KQ++V+RGQI NL  AL+  KTP QLV+M P+ +E
Sbjct:   50 ERQPLLDRDRGGSPRDPHRNEFSEDPEFREIVRKAERAIDEGIYPERIYQGSSGSYFVKDSQGKIIGVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTRVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFHRIGLPPKVGSFQLFVDGYKDA--DFWLRRFEAEPLPENTNRQLQLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDTSGNRDTD---------WVVVKDPIIKIAAIDNGLAFPLKHPDSWRAYPFYWAWLAQAKVPFSQEIRELVLPKLSDPNFIKDLEEDLYELFKKDPGFDRGQFHKQISVMRGQILNLSQALKDGKTPLQLVQMPPVIVE 419
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Cavefish
Match: pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:NCBI gene;Acc:103023819])

HSP 1 Score: 336.265 bits (861), Expect = 5.335e-110
Identity = 179/381 (46.98%), Postives = 238/381 (62.47%), Query Frame = 1 
Query:  178 ENYRLVQNDLSDKNRDLFLHSTIED-----VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            E   L+  D     RD   +   ED     +V  AE A D+ I P  I QGSSGSYFV++   +IIGVFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP TR+  L S  FN++ ++ +KS+ K    E  P +G++FHR+G+PPK GS Q+FV  Y+ A            P+      +   +F++LVVLDYIIRNTDR N NWLIK+   +++    D +              +  IKIAAIDNGLAFP KHPD  R YP+YW+WL+ A VPF   I  L+LPKL D  F++ + ++L  LFK +  F +  F KQ++V+RGQI NL  AL+  KTP QLV+M P+ +E
Sbjct:   50 ERQPLLDRDRGGSPRDPHRNEFSEDPEFREIVRKAERAIDEGIYPERIYQGSSGSYFVKDSQGKIIGVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTRVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFHRIGLPPKVGSFQLFVDGYKDA--DFWLRRFEAEPLPENTNRQLQLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDTSGNRDTD---------WVVVKDPIIKIAAIDNGLAFPLKHPDSWRAYPFYWAWLAQAKVPFSQEIRELVLPKLSDPNFIKDLEEDLYELFKKDPGFDRGQFHKQISVMRGQILNLSQALKDGKTPLQLVQMPPVIVE 419
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Cavefish
Match: pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:NCBI gene;Acc:103023819])

HSP 1 Score: 335.495 bits (859), Expect = 2.321e-109
Identity = 179/381 (46.98%), Postives = 238/381 (62.47%), Query Frame = 1 
Query:  178 ENYRLVQNDLSDKNRDLFLHSTIED-----VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            E   L+  D     RD   +   ED     +V  AE A D+ I P  I QGSSGSYFV++   +IIGVFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP TR+  L S  FN++ ++ +KS+ K    E  P +G++FHR+G+PPK GS Q+FV  Y+ A            P+      +   +F++LVVLDYIIRNTDR N NWLIK+   +++    D +              +  IKIAAIDNGLAFP KHPD  R YP+YW+WL+ A VPF   I  L+LPKL D  F++ + ++L  LFK +  F +  F KQ++V+RGQI NL  AL+  KTP QLV+M P+ +E
Sbjct:   50 ERQPLLDRDRGGSPRDPHRNEFSEDPEFREIVRKAERAIDEGIYPERIYQGSSGSYFVKDSQGKIIGVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTRVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFHRIGLPPKVGSFQLFVDGYKDA--DFWLRRFEAEPLPENTNRQLQLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDTSGNRDTD---------WVVVKDPIIKIAAIDNGLAFPLKHPDSWRAYPFYWAWLAQAKVPFSQEIRELVLPKLSDPNFIKDLEEDLYELFKKDPGFDRGQFHKQISVMRGQILNLSQALKDGKTPLQLVQMPPVIVE 419
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Cavefish
Match: pi4k2b (phosphatidylinositol 4-kinase type 2 beta [Source:NCBI gene;Acc:564750])

HSP 1 Score: 327.791 bits (839), Expect = 1.719e-106
Identity = 175/396 (44.19%), Postives = 246/396 (62.12%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTK--YWKRPFF 1431
            ++V  AE A +  + P  I QGSSGSYFV++   +IIGVFKPK EEPY   NPKW+KYFH++CCPCCFGR CL+ N GYLSE  AS++D+ L L +VP T++  L S  F++N ++  KS+ K +  E  P +GR+FHR+G+PPK GS Q+FV  Y  A            P+   ++++   +F++LVVLDY+IRNTDR N NWLIK++   + +  +         G++     +  I+IAAIDNGLAFP+KHPD+ R YP++W+WL  A VPF      L+L ++ D  FV+ + ++L  LFK +  F K++FEKQM+V+RGQI NL  AL+  K+P QLV+M  + +             ERSR        R  Q+ N  T+  + KRPFF
Sbjct:   97 EIVQRAEQAIESGVCPERISQGSSGSYFVKDPKGKIIGVFKPKSEEPYGHLNPKWTKYFHKVCCPCCFGRGCLVPNQGYLSEAAASLVDQKLGLEVVPKTKVVSLASETFHYNAIDRAKSRGKKYALEKVPKVGRRFHRVGLPPKVGSFQLFVEGYHEA--DYWLRKFEAEPLPENMRKQLQSQFERLVVLDYVIRNTDRGNDNWLIKYEKAGDEEQSE--------KGSEWSEPKDCAIQIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSQETRDLVLSRISDMNFVQDLCEDLYELFKTDKGFDKTMFEKQMSVMRGQILNLTQALKDGKSPIQLVQMPRVVV-------------ERSRGG---GQGRVVQLGNAFTQTFHCKRPFF 466
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Cavefish
Match: pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:NCBI gene;Acc:103023819])

HSP 1 Score: 193.741 bits (491), Expect = 3.284e-56
Identity = 108/248 (43.55%), Postives = 152/248 (61.29%), Query Frame = 1 
Query:  562 LTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
            L S  FN++ ++ +KS+ K    E  P +G++FHR+G+PPK GS Q+FV  Y+ A+  +        P+      +   +F++LVVLDYIIRNTDR N NWLIK+   +++    D +              +  IKIAAIDNGLAFP KHPD  R YP+YW+WL+ A VPF   I  L+LPKL D  F++ + ++L  LFK +  F +  F KQ++V+RGQI NL  AL+  KTP QLV+M P+ +E
Sbjct:  116 LASETFNYSAIDRVKSRGKRLALEKVPKVGQRFHRIGLPPKVGSFQLFVDGYKDADFWLRRFEAE--PLPENTNRQLQLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDTSGNRDTD---------WVVVKDPIIKIAAIDNGLAFPLKHPDSWRAYPFYWAWLAQAKVPFSQEIRELVLPKLSDPNFIKDLEEDLYELFKKDPGFDRGQFHKQISVMRGQILNLSQALKDGKTPLQLVQMPPVIVE 352
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Sea Lamprey
Match: pi4k2b (phosphatidylinositol 4-kinase type 2 beta [Source:NCBI gene;Acc:564750])

HSP 1 Score: 294.278 bits (752), Expect = 4.598e-96
Identity = 159/350 (45.43%), Postives = 213/350 (60.86%), Query Frame = 1 
Query:  349 QEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYN 1398
            Q+++GVFKPKDEEPY   NPKW+K+ H+ CCPCCFGR CL+ NHGYLSE GAS++D+ LELN+VP T++  L    F + P++  KS+ K    E  P +GR F R+G+PPK GSLQ+FV  Y+ A            P+    +++F  +F++LVVLDYIIRNTDR N NWLIK+   ++     D                   IKIAAIDNGLAFP+KHPD  R YP+YW+WL  A V F   I  L+LPKL D+ FV+ +  +L  L K +  F K  F+KQM+V+RGQI NL  AL + KTP          L+L+N    +V ++ RSR+ S     R +  ++
Sbjct:    1 QKVVGVFKPKDEEPYGHLNPKWTKWVHKNCCPCCFGRGCLVPNHGYLSEAGASLVDQKLELNVVPKTKVVHLACKTFYYGPIDRCKSQGKKFTMEKIPSVGRMFRRVGLPPKVGSLQLFVDGYKDA--DFWLRRFETEPLPENTRKQFQLQFERLVVLDYIIRNTDRGNDNWLIKYDCPVSDNRDSDW-----------LMVKEPVIKIAAIDNGLAFPFKHPDSWRAYPFYWAWLPQAKVQFSQEIRELVLPKLEDTSFVQDLCHDLFDLCKDDKGFDKHTFDKQMSVMRGQIMNLERALHEGKTP----------LDLVNMPHIVVESASRSRSTSFIQIIRSKPFFS 327
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Sea Lamprey
Match: pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:NCBI gene;Acc:406667])

HSP 1 Score: 135.961 bits (341), Expect = 8.313e-38
Identity = 82/182 (45.05%), Postives = 111/182 (60.99%), Query Frame = 1 
Query:  454 GRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLA 999
            GR+CL+ N GYLSE GAS++D  L LNIVP T++  L S AF++  ++  KS+ K    E  P++GR+FHR+G+PPK GSLQ+FV  Y+ A          + P+     ++   EF+KLV LDYIIRNTDR N NWLIK++ R  +  KD     + A            ++IAAIDNGLA
Sbjct:    1 GRDCLVLNQGYLSEAGASLVDSTLGLNIVPKTKVVWLASEAFHYGAIDRAKSRGKKLALERVPEIGRRFHRIGLPPKVGSLQLFVEGYKDA--EDWLRRFEVEPLPENTNKQLQLEFEKLVCLDYIIRNTDRGNDNWLIKYEPRKETD-KDTEQEREPA------------VRIAAIDNGLA 167
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Yeast
Match: LSB6 (Type II phosphatidylinositol 4-kinase; binds Las17p, a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization [Source:SGD;Acc:S000003636])

HSP 1 Score: 102.064 bits (253), Expect = 2.597e-23
Identity = 58/138 (42.03%), Postives = 77/138 (55.80%), Query Frame = 1 
Query:  184 YRLVQNDLSDKNRDLFLHSTIEDVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQE---IIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHN 588
            Y  ++     + R+ F H  + D + A E    +++    I  GSSGSYFV     +    +GVFKPKDEEPY   +PKW+K+ HR   PC FGR CLI N GY+ E  AS+LD  LE ++VP T  A + S  F  N
Sbjct:  131 YEQLRRKEEQEQRENFNH-LVSDCIEAVETFG-RELE--RIQTGSSGSYFVYGTRADESVPVGVFKPKDEEPYGPFSPKWTKWAHRTFFPCLFGRSCLIPNLGYICESAASLLDRRLETHLVPYTDTASIESFNFYDN 264

HSP 2 Score: 93.5893 bits (231), Expect = 1.174e-20
Identity = 53/156 (33.97%), Postives = 84/156 (53.85%), Query Frame = 1 
Query:  823 DYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIA--SVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQ-KKTPAQLV 1281
            DYI+RNTDR   NW++K     N++ +                     +K+AAIDNGL+FP+KHPD+ R+YPY W +L +   + PF +++    LP L  + + E+       LF  +  F   +++KQ AVL+GQ  N+   L+  ++ P +LV
Sbjct:  380 DYIMRNTDRGLDNWMVKLIKLSNNKWR---------------------LKLAAIDNGLSFPWKHPDEWRLYPYGWLYLPLQLLAKPFSEQMRSHFLPILTSTNWWEESYQEFLALFSRDQDFNVRMWKKQWAVLKGQAFNVVETLKDPRQGPLELV 514
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Nematostella
Match: EDO35290 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM03])

HSP 1 Score: 322.013 bits (824), Expect = 1.145e-105
Identity = 181/384 (47.14%), Postives = 242/384 (63.02%), Query Frame = 1 
Query:  253 VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLK-----DDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQ 1389
            V+ AAE A D  I P  I QGSSGSYFV+N   + IGVFKPKDEEPY   NPKW+K+ H++CCPCCFGR  L+ N GY+SE GAS++D  L LNIVP T++ +L S  FN+   +  K+++K    E FPD   K  + G+PPK GS Q+FV +++ A            P+ S+  ++FL +FQK+V LDYIIRNTDR N NWLIK++     + +     D   A D+ +  +        I +AAIDNGLAFPYKHPD  R YP+YW+WLS A  PF D I  ++LP+L D  FV  + D+L +LF  +  F +S FEKQM+++RGQI NL  ALR  K+P QLV+M  +T+E     D +    +R R++S DA T+  Q
Sbjct:   22 VIRAAEQAIDAGILPERIYQGSSGSYFVKNKEGKKIGVFKPKDEEPYGHLNPKWTKWCHKMCCPCCFGRHMLVPNQGYMSEAGASLVDRKLGLNIVPKTKVVRLASDTFNYTAFDRAKARSKKFATERFPDSLGKHVKAGLPPKVGSFQMFVDEFKDA--EFHLRRFESEPLPSQTYKDFLLQFQKMVCLDYIIRNTDRGNDNWLIKYEKTPEVETETVKTADGETAWDVVSPPK--------IYVAAIDNGLAFPYKHPDSWRAYPFYWAWLSHAKEPFLDEIKDMVLPQLSDMNFVTDLTDDLYVLFHEDKGFDRSTFEKQMSLVRGQILNLSQALRDSKSPLQLVQMPVVTVER-KKGDGL----DRGRSHS-DAFTQSFQ 389
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Medaka
Match: pi4k2a (phosphatidylinositol 4-kinase type 2 alpha [Source:NCBI gene;Acc:101169092])

HSP 1 Score: 327.791 bits (839), Expect = 4.091e-106
Identity = 166/354 (46.89%), Postives = 230/354 (64.97%), Query Frame = 1 
Query:  244 IEDVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLE 1305
              +++  AE A ++ I P  I QGSSGSYFV++   ++IGVFKPK+EEPY   NPKW+K+  +LCCPCCFGR+CL+ N GYLSE GAS++D+ LELNIVP T++  L S  FN++ ++ +KS+ K    E  P +G++FHR+G+PPK GS Q+FV  Y+ A            P+      +   +F++LVVLDYIIRNTDR N NWL+K+   +++    D +              +  IK+AAIDNGLAFP KHPD  R YP+YW+WL+ A VPF   I  L++PKL D  F++ + ++L  LFK +  F +  F KQ+AV+RGQI NL  ALR  KTP QLV++ P+ +E
Sbjct:  127 FREIIRKAEQAIEEGIYPERIYQGSSGSYFVKDAQGKVIGVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFHRIGLPPKVGSFQLFVDGYKDA--DFWLRKFEADPLPENTNRQLQLQFERLVVLDYIIRNTDRGNDNWLLKYDCPMDAIGNRDTD---------WVVVKDPVIKLAAIDNGLAFPLKHPDSWRAYPFYWAWLAQAKVPFSQEIQDLVVPKLSDPNFIKDLEEDLYELFKKDPGFDRGQFHKQVAVMRGQILNLNQALRDGKTPLQLVQLPPVIVE 469
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Medaka
Match: pi4k2b (phosphatidylinositol 4-kinase type 2 beta [Source:NCBI gene;Acc:101171306])

HSP 1 Score: 324.324 bits (830), Expect = 6.241e-105
Identity = 175/396 (44.19%), Postives = 242/396 (61.11%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTK--YWKRPFF 1431
            D++  AE A +  + P  I QGSSGSYFV++   +IIGVFKPK EEPY   NPKW+KYFH+LCCPCCFGR CL+ N GYLSE  AS++D  L L +VP T++  L S  F+++ ++  KS+ K +  E  P +GR+FHR+G+PPK GS Q+FV  Y  A            P+    +++   +F++LVVLDY+IRNTDR N NWLIK++           N G+   G +    +   IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A V F      L+L +L D  FV+ + ++L  LFK +  F K++FE+QM+V+RGQ+ NL  AL+  K+P QLV+M  + +             ERSR+       R   + N  T+  + KRPFF
Sbjct:  118 DIIQRAEQAIEGGVCPERISQGSSGSYFVKDSKGKIIGVFKPKSEEPYGHLNPKWTKYFHKLCCPCCFGRGCLLPNQGYLSEAAASLVDTKLGLGVVPKTKVVYLASETFHYSAIDRAKSRGKKYALEKVPKVGRRFHRVGLPPKVGSFQLFVEGYREA--DHWLRRFEAEPLPENTRKQLQSQFERLVVLDYVIRNTDRGNDNWLIKYE-----------NPGESGEGQKSSPDSC--IKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVAFSQETRELVLSRLSDMNFVQDLCEDLYELFKADKGFDKTMFERQMSVMRGQVLNLTQALKDGKSPIQLVQMPRVVV-------------ERSRSG---GQGRVVTLGNAFTQTFHCKRPFF 482
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Medaka
Match: pi4k2b (phosphatidylinositol 4-kinase type 2 beta [Source:NCBI gene;Acc:101171306])

HSP 1 Score: 323.168 bits (827), Expect = 2.041e-104
Identity = 177/400 (44.25%), Postives = 245/400 (61.25%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXX----XXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTK--YWKRPFF 1431
            D++  AE A +  + P  I QGSSGSYFV++   +IIGVFKPK EEPY   NPKW+KYFH+LCCPCCFGR CL+ N GYLSE  AS++D  L L +VP T++  L S  F+++ ++  KS+ K +  E  P +GR+FHR+G+PPK GS Q+FV  Y  A            P+    +++   +F++LVVLDY+IRNTDR N NWLIK++           N G+   G ++     S  +S IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A V F      L+L +L D  FV+ + ++L  LFK +  F K++FE+QM+V+RGQ+ NL  AL+  K+P QLV+M  + +             ERSR+       R   + N  T+  + KRPFF
Sbjct:  123 DIIQRAEQAIEGGVCPERISQGSSGSYFVKDSKGKIIGVFKPKSEEPYGHLNPKWTKYFHKLCCPCCFGRGCLLPNQGYLSEAAASLVDTKLGLGVVPKTKVVYLASETFHYSAIDRAKSRGKKYALEKVPKVGRRFHRVGLPPKVGSFQLFVEGYREA--DHWLRRFEAEPLPENTRKQLQSQFERLVVLDYVIRNTDRGNDNWLIKYE-----------NPGESGEGQKEAEWPESSPDSCIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVAFSQETRELVLSRLSDMNFVQDLCEDLYELFKADKGFDKTMFERQMSVMRGQVLNLTQALKDGKSPIQLVQMPRVVV-------------ERSRSG---GQGRVVTLGNAFTQTFHCKRPFF 493
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Medaka
Match: pi4k2b (phosphatidylinositol 4-kinase type 2 beta [Source:NCBI gene;Acc:101171306])

HSP 1 Score: 286.574 bits (732), Expect = 1.640e-90
Identity = 167/400 (41.75%), Postives = 229/400 (57.25%), Query Frame = 1 
Query:  250 DVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXX----XXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTK--YWKRPFF 1431
            D++  AE A +  + P  I QGSSGSYFV++   +IIGVFKPK EEPY   NPKW+KYFH+LCCPCCFGR CL+ N GYLSE  AS++D  L L +VP T++  L S  F+++ ++  KS+ K +  E  P +GR+FHR+G+PPK GS Q+FV  Y  A            P+    +++   +F++LVVLDY+IRNTDR N NWLIK++           N G+   G ++     S  +S IKIAAIDNGLAFP+KHPD+ R YP++W+WL  A V F      L+L +L D  FV+ + ++L  LFK                    + NL  AL+  K+P QLV+M  + +             ERSR+       R   + N  T+  + KRPFF
Sbjct:  123 DIIQRAEQAIEGGVCPERISQGSSGSYFVKDSKGKIIGVFKPKSEEPYGHLNPKWTKYFHKLCCPCCFGRGCLLPNQGYLSEAAASLVDTKLGLGVVPKTKVVYLASETFHYSAIDRAKSRGKKYALEKVPKVGRRFHRVGLPPKVGSFQLFVEGYREA--DHWLRRFEAEPLPENTRKQLQSQFERLVVLDYVIRNTDRGNDNWLIKYE-----------NPGESGEGQKEAEWPESSPDSCIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVAFSQETRELVLSRLSDMNFVQDLCEDLYELFK--------------------VLNLTQALKDGKSPIQLVQMPRVVV-------------ERSRSG---GQGRVVTLGNAFTQTFHCKRPFF 473
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Planmine SMEST
Match: SMESG000035623.1 (SMESG000035623.1)

HSP 1 Score: 791.186 bits (2042), Expect = 0.000e+0
Identity = 424/424 (100.00%), Postives = 424/424 (100.00%), Query Frame = 1 
Query:  169 MSDENYRLVQNDLSDKNRDLFLHSTIEDVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTKYWKRPFFRKF 1440
            MSDENYRLVQNDLSDKNRDLFLHSTIEDVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAENCIENLLNNILPVDSELQEEFLFEFQKLVVLDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIANGNQQGSQNNSFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTKYWKRPFFRKF
Sbjct:    1 MSDENYRLVQNDLSDKNRDLFLHSTIEDVVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAENCIENLLNNILPVDSELQEEFLFEFQKLVVLDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIANGNQQGSQNNSFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTKYWKRPFFRKF 424
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Planmine SMEST
Match: SMESG000005714.1 (SMESG000005714.1)

HSP 1 Score: 341.273 bits (874), Expect = 9.539e-113
Identity = 189/394 (47.97%), Postives = 253/394 (64.21%), Query Frame = 1 
Query:  253 VVHAAELASDKDINPTIIPQGSSGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECLITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTKTHIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQS-RINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIYNYVTKYWKRPFF 1431
            +++  E+A D  I P +IPQGSSGSYFV+N   EI GVFKPKDEEPY   NPKW+K+ HR  CPCCFGR CL+ N GYLSE  ASI+D+ML L+IVP T++ +L S +FN++ ++  K   K  +A  FP +GR+FHR+G+PPK GSLQ+FV +Y+ AE  + N+  ++  +  + + EF  EF+KLVVLDYIIRNTDR N NWLI ++  R+    K+D N   +             IK+AAIDNGLAFPYKHPD+ R YP+YW WL +A +PF D I  L+L KL D  FVE +   L  LF+++  FKK+ F  QMAV+RGQI NL  AL+++ TP  LV M  +          I+  +++ R +       +   +N  T Y KRPFF
Sbjct:   32 ILNEVEIAIDIGIKPVMIPQGSSGSYFVKNGMGEICGVFKPKDEEPYGVLNPKWTKWIHRTVCPCCFGRSCLLPNQGYLSEAAASIVDQMLGLDIVPQTKVVRLVSESFNYDAIDKAKCNAKKKVANRFPKIGRRFHRIGLPPKIGSLQLFVKNYKDAEYWLSNIKFDL--LSDQTKAEFQLEFEKLVVLDYIIRNTDRGNDNWLISYECPRVTDSQKEDGNWNLVIQPK---------IKVAAIDNGLAFPYKHPDEWRAYPFYWVWLPMAKIPFSDSIKDLVLSKLLDQDFVESICKKLFNLFRLDKDFKKTTFRDQMAVMRGQIFNLSTALQKRLTPYDLVNMPVI----------IIRRNKKKREDVPQQDDLEDSDFN--TYYPKRPFF 402
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Planmine SMEST
Match: SMESG000020603.1 (SMESG000020603.1)

HSP 1 Score: 180.259 bits (456), Expect = 7.953e-53
Identity = 121/265 (45.66%), Postives = 154/265 (58.11%), Query Frame = 1 
Query:  646 LGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIY---NYVTKYWKRPFF 1431
            + RKFHRLG+PPK GS Q+FVS+Y+ AE  +    +  LP   +   +F FEF+KLVVLDYIIRNTDR N NWLIK+     S    D    D +N  +        IKIAAIDNGLAFPYKHPD+ R YP++W+W S+A  PF D I  L+LPKL DS FV+ +  +L   FK +  F    F KQMAV+RGQI NL  +L++  +P  LV M  +T+       N         T + D +     IY   +  T Y KRPFF
Sbjct:    1 MARKFHRLGLPPKVGSFQLFVSNYKDAEYWLSRFDSETLP--EQTFRKFRFEFEKLVVLDYIIRNTDRGNDNWLIKYDKSETSSNSGDTGEWDFSNVPE--------IKIAAIDNGLAFPYKHPDEWRAYPFHWTWSSMAKHPFSDEIKQLVLPKLLDSSFVQSLCTSLYDEFKTDKGFDNHTFSKQMAVMRGQILNLTNSLQRNYSPLDLVRMPVVTISKYADFQN-------DPTRNLDLA-HHHSIYDDDDLFTSYHKRPFF 247
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Planmine SMEST
Match: SMESG000020603.1 (SMESG000020603.1)

HSP 1 Score: 177.178 bits (448), Expect = 1.279e-51
Identity = 120/265 (45.28%), Postives = 154/265 (58.11%), Query Frame = 1 
Query:  646 LGRKFHRLGVPPKFGSLQIFVSDYESAXXXXXXXXXXXXPVDSXXXXXXXXXXXXXXXXDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNAGDIAXXXXXXXXXXXFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIASVPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVLRGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTDASTRKQQIY---NYVTKYWKRPFF 1431
            + RKFHRLG+PPK GS Q+FVS+Y+ AE  +    +  LP   +   +F FEF+KLVVLDYIIRNTDR N NWLIK+     S    + + G+    N         IKIAAIDNGLAFPYKHPD+ R YP++W+W S+A  PF D I  L+LPKL DS FV+ +  +L   FK +  F    F KQMAV+RGQI NL  +L++  +P  LV M  +T+       N         T + D +     IY   +  T Y KRPFF
Sbjct:    1 MARKFHRLGLPPKVGSFQLFVSNYKDAEYWLSRFDSETLP--EQTFRKFRFEFEKLVVLDYIIRNTDRGNDNWLIKYDKSETSSNSVNGDTGEWDFSNVPE------IKIAAIDNGLAFPYKHPDEWRAYPFHWTWSSMAKHPFSDEIKQLVLPKLLDSSFVQSLCTSLYDEFKTDKGFDNHTFSKQMAVMRGQILNLTNSLQRNYSPLDLVRMPVVTISKYADFQN-------DPTRNLDLA-HHHSIYDDDDLFTSYHKRPFF 249
The following BLAST results are available for this feature:
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
PI4K2B2.717e-10748.01phosphatidylinositol 4-kinase type 2 beta [Source:... [more]
PI4K2B6.184e-10648.01phosphatidylinositol 4-kinase type 2 beta [Source:... [more]
PI4K2A1.533e-10548.04phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
AL355315.11.155e-9347.66novel protein[more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ZC8.64.186e-9144.18pep chromosome:WBcel235:X:4972575:4997598:-1 gene:... [more]
C56A3.82.366e-5937.00pep chromosome:WBcel235:V:13560278:13561992:1 gene... [more]
C56A3.83.786e-5937.40pep chromosome:WBcel235:V:13560494:13561885:1 gene... [more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Pi4KIIalpha2.269e-5447.71gene:FBgn0037339 transcript:FBtr0078755[more]
Pi4KIIalpha1.320e-5347.71gene:FBgn0037339 transcript:FBtr0078757[more]
Pi4KIIalpha1.320e-5347.71gene:FBgn0037339 transcript:FBtr0078756[more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
pi4k2a5.313e-10744.01phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
pi4k2a5.313e-10744.01phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
pi4k2b9.034e-10644.19phosphatidylinositol 4-kinase type 2 beta [Source:... [more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dtx43.057e-11248.58Xenopus tropicalis phosphatidylinositol 4-kinase t... [more]
dtx41.682e-11048.58Xenopus tropicalis phosphatidylinositol 4-kinase t... [more]
pi4k2a2.988e-10548.18phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
pi4k2a1.343e-10448.03phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
pi4k2a2.020e-9446.67phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pi4k2b1.123e-10546.81phosphatidylinositol 4-kinase type 2 beta [Source:... [more]
Pi4k2a1.326e-10347.35phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
Pi4k2a1.326e-10347.35phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
Pi4k2b1.136e-9446.93phosphatidylinositol 4-kinase type 2 beta [Source:... [more]
Pi4k2a6.921e-7245.99phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q28G26|P4K2B_XENTR9.553e-11248.58Phosphatidylinositol 4-kinase type 2-beta OS=Xenop... [more]
sp|Q6DCQ8|P4K2B_XENLA1.595e-11048.01Phosphatidylinositol 4-kinase type 2-beta OS=Xenop... [more]
sp|Q6PE18|P4K2A_DANRE4.010e-10644.01Phosphatidylinositol 4-kinase type 2-alpha OS=Dani... [more]
sp|Q8TCG2|P4K2B_HUMAN2.970e-10548.01Phosphatidylinositol 4-kinase type 2-beta OS=Homo ... [more]
sp|Q5XIL2|P4K2B_RAT3.266e-10546.54Phosphatidylinositol 4-kinase type 2-beta OS=Rattu... [more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3IMP56.564e-11748.48phosphatidylinositol 4-kinase type 2-beta isoform ... [more]
A0A443QFU52.987e-11352.97Phosphatidylinositol 4-kinase type 2-alpha-like is... [more]
R7UKK83.374e-11348.95PI3K/PI4K domain-containing protein OS=Capitella t... [more]
A0A1S3INJ54.932e-11347.28phosphatidylinositol 4-kinase type 2-alpha isoform... [more]
A0A1S3IN128.259e-11246.15phosphatidylinositol 4-kinase type 2-beta isoform ... [more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pi4k2a4.010e-11046.98phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
pi4k2a5.335e-11046.98phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
pi4k2a2.321e-10946.98phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
pi4k2b1.719e-10644.19phosphatidylinositol 4-kinase type 2 beta [Source:... [more]
pi4k2a3.284e-5643.55phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pi4k2b4.598e-9645.43phosphatidylinositol 4-kinase type 2 beta [Source:... [more]
pi4k2a8.313e-3845.05phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
LSB62.597e-2342.03Type II phosphatidylinositol 4-kinase; binds Las17... [more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO352901.145e-10547.14Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
pi4k2a4.091e-10646.89phosphatidylinositol 4-kinase type 2 alpha [Source... [more]
pi4k2b6.241e-10544.19phosphatidylinositol 4-kinase type 2 beta [Source:... [more]
pi4k2b2.041e-10444.25phosphatidylinositol 4-kinase type 2 beta [Source:... [more]
pi4k2b1.640e-9041.75phosphatidylinositol 4-kinase type 2 beta [Source:... [more]
back to top
BLAST of Phosphatidylinositol 4-kinase type 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000035623.10.000e+0100.00SMESG000035623.1[more]
SMESG000005714.19.539e-11347.97SMESG000005714.1[more]
SMESG000020603.17.953e-5345.66SMESG000020603.1[more]
SMESG000020603.11.279e-5145.28SMESG000020603.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007394 ID=SMED30007394|Name=Phosphatidylinositol 4-kinase type 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1628bp
GTGGTATAATTATTAAATTTATTAGATTTAATTTTTTAAGCATTACAATA
TTTTTCTGAGATCGTATTATTTTTTCTGAAACCAAAGTCTCTACATTTAA
CAAAATTTATAAAATGATCTATTGATATTACTTTTAGTCATTGAAAGAGT
CTAAATATTTTTTTTAAAATGTCAGATGAAAATTATCGGCTTGTCCAAAA
TGATTTATCTGATAAAAATCGAGACCTTTTTCTTCATTCAACCATCGAAG
ACGTTGTTCACGCTGCTGAACTCGCTAGCGATAAAGACATAAATCCAACA
ATTATACCACAAGGTTCAAGTGGCAGTTACTTTGTTCGAAATTGCAATCA
AGAAATAATTGGTGTTTTTAAACCAAAGGATGAAGAACCATATGAAAGCC
AAAATCCAAAATGGTCAAAATATTTTCATCGTTTGTGTTGTCCATGTTGT
TTTGGGCGTGAATGTTTGATAACAAATCATGGATACTTATCTGAAGTTGG
GGCTAGTATACTTGATGAAATGCTGGAATTGAATATCGTTCCTACAACGA
GATTGGCTCAGTTAACAAGTTTAGCATTCAATCATAATCCATTAAATATT
ATGAAGTCAAAAACTAAAACTCATATCGCAGAAACATTTCCTGACTTAGG
ACGTAAATTTCATCGACTCGGAGTTCCTCCAAAATTTGGATCTCTGCAAA
TTTTTGTTTCTGATTATGAATCAGCTGAAAATTGCATAGAAAACCTTTTA
AATAATATCTTACCAGTAGATTCTGAGTTGCAAGAAGAATTTCTATTTGA
ATTCCAGAAATTGGTCGTATTGGATTACATAATCCGCAATACTGATCGTA
ACAATAGCAATTGGTTGATTAAGTGGCAATCTCGAATCAATAGCCAATTA
AAGGATGATTTGAACGCCGGTGACATAGCTAACGGAAATCAACAAGGTTC
TCAAAATAATTCTTTTATTAAAATCGCTGCAATCGATAATGGCTTGGCTT
TTCCTTACAAACATCCAGATCAAATGAGAATCTATCCGTATTATTGGAGT
TGGCTTTCGATTGCCAGTGTTCCATTCTGTGATCGGATCTCACTGCTTTT
ACTCCCAAAATTGGGAGATTCGGTTTTTGTTGAGAAAATGATTGATAATC
TTAATTTATTATTTAAGATCAATAATCATTTCAAAAAATCGGTATTTGAA
AAACAAATGGCAGTATTGCGTGGTCAAATAACTAATTTATGTGCCGCACT
TCGTCAAAAAAAGACTCCAGCTCAACTAGTTGAAATGGCTCCAATGACAC
TAGAACTAATTAATAGTACCGATAACATCGTTCCCAACTCAGAACGTTCA
CGGACTAATTCAACGGACGCCTCTACTCGTAAGCAACAAATATATAACTA
TGTCACGAAATATTGGAAAAGACCTTTCTTTCGGAAATTCTAGATTATTG
AAGCTGCAATTTGAGTCTTTCTTAGATTTGCCAAAACATTAAATTTGGTT
ATATTGTGTACTTGATAACGGAGCTTCAACAAATTTCTGTTACGTAACAT
TTTATTGAAGTGAGTGATGAATTTCTATTTACACAATTTGTCAACAGTGT
CTTGTTTTAAATCTCAAAAATAAATCTG
back to top

protein sequence of SMED30007394-orf-1

>SMED30007394-orf-1 ID=SMED30007394-orf-1|Name=SMED30007394-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=425bp
MSDENYRLVQNDLSDKNRDLFLHSTIEDVVHAAELASDKDINPTIIPQGS
SGSYFVRNCNQEIIGVFKPKDEEPYESQNPKWSKYFHRLCCPCCFGRECL
ITNHGYLSEVGASILDEMLELNIVPTTRLAQLTSLAFNHNPLNIMKSKTK
THIAETFPDLGRKFHRLGVPPKFGSLQIFVSDYESAENCIENLLNNILPV
DSELQEEFLFEFQKLVVLDYIIRNTDRNNSNWLIKWQSRINSQLKDDLNA
GDIANGNQQGSQNNSFIKIAAIDNGLAFPYKHPDQMRIYPYYWSWLSIAS
VPFCDRISLLLLPKLGDSVFVEKMIDNLNLLFKINNHFKKSVFEKQMAVL
RGQITNLCAALRQKKTPAQLVEMAPMTLELINSTDNIVPNSERSRTNSTD
ASTRKQQIYNYVTKYWKRPFFRKF*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
Vocabulary: INTERPRO
TermDefinition
IPR039756Lsb6/PI4K2
IPR000403PI3/4_kinase_cat_dom
Vocabulary: molecular function
TermDefinition
GO:0016301kinase activity
GO:0000166nucleotide binding
GO:00044301-phosphatidylinositol 4-kinase activity
GO:0005524ATP binding
GO:0016740transferase activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005768endosome
GO:0005802trans-Golgi network
GO:0005886plasma membrane
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0007030Golgi organization
GO:0007032endosome organization
GO:0016310phosphorylation
GO:0046854phosphatidylinositol phosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000403Phosphatidylinositol 3-/4-kinase, catalytic domainPFAMPF00454PI3_PI4_kinasecoord: 49..356
e-value: 2.9E-44
score: 151.8
IPR039756Type II phosphatidylinositol 4-kinase Lsb6/PI4K2PANTHERPTHR12865PHOSPHATIDYLINOSITOL 4-KINASE TYPE-IIcoord: 17..422