TPA_inf: Pax-beta2 paired domain protein

Overview
NameTPA_inf: Pax-beta2 paired domain protein (DAA12514.1)
Smed IDSMED30007365
Length (bp)1538
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of TPA_inf: Pax-beta2 paired domain protein (SMED30007365) t-SNE clustered cells

Violin plots show distribution of expression levels for TPA_inf: Pax-beta2 paired domain protein (SMED30007365) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TPA_inf: Pax-beta2 paired domain protein (SMED30007365) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TPA_inf: Pax-beta2 paired domain protein (SMED30007365) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30007365

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30007365h1SMcG0017066 SmedASXL_012761SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
muscle cellSMED30007365h1SMcG0017066 dd_Smed_v4_14362_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Human
Match: PAX5 (paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619])

HSP 1 Score: 159.073 bits (401), Expect = 4.043e-44
Identity = 82/144 (56.94%), Postives = 102/144 (70.83%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    +       G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTSRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Human
Match: PAX5 (paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619])

HSP 1 Score: 158.688 bits (400), Expect = 4.498e-44
Identity = 82/144 (56.94%), Postives = 102/144 (70.83%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    +       G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTSRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Human
Match: PAX5 (paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619])

HSP 1 Score: 159.458 bits (402), Expect = 4.927e-44
Identity = 82/144 (56.94%), Postives = 102/144 (70.83%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    +       G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTSRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Human
Match: PAX5 (paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619])

HSP 1 Score: 159.458 bits (402), Expect = 5.634e-44
Identity = 82/144 (56.94%), Postives = 102/144 (70.83%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    +       G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTSRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Human
Match: PAX5 (paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619])

HSP 1 Score: 159.458 bits (402), Expect = 6.820e-44
Identity = 82/144 (56.94%), Postives = 102/144 (70.83%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    +       G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTSRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Celegans
Match: pax-2 (PAX (Paired box) transcription factor [Source:UniProtKB/TrEMBL;Acc:U4PCL3])

HSP 1 Score: 163.31 bits (412), Expect = 3.037e-46
Identity = 83/151 (54.97%), Postives = 110/151 (72.85%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAAASETSDN 873
             +NQ G  F NGRPLP+ +R +I++++    RPCDISRQL VSHGCVSKIL RY  TGS+ PG IGGSKPKV TP +V+ +  YK  NP ++AWEIRQKLIEDQ+C E++ PS+SSINRI+R+K  ++ + A+ +   P  +  +S TS N
Sbjct:   32 GVNQLGGVFVNGRPLPDTIRAQIVEMSQHGTRPCDISRQLKVSHGCVSKILGRYYSTGSVRPGVIGGSKPKVATPRVVECIAGYKRANPTMFAWEIRQKLIEDQICGEENVPSVSSINRIVRNKSFMA-QLATPTSVTPSVARPSSATSQN 181          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Celegans
Match: egl-38 (PAX protein [Source:UniProtKB/TrEMBL;Acc:G5ED14])

HSP 1 Score: 162.925 bits (411), Expect = 4.894e-46
Identity = 82/149 (55.03%), Postives = 108/149 (72.48%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAAASETS 867
             +NQ G  F NGRPL + +R +I++++    RPCDISRQL VSHGCVSKIL RY  TGS+ PG IGGSKPKV TP +V+ +  YK  NP ++AWEIRQKLIEDQ+C E++ PS+SSINRI+R+K  ++  +A  S    + S+AA  +S
Sbjct:   32 GVNQLGGVFVNGRPLADTVRAQIVEMSQHGTRPCDISRQLKVSHGCVSKILGRYYSTGSVRPGVIGGSKPKVATPRVVECIAGYKRANPTMFAWEIRQKLIEDQICGEENVPSVSSINRIVRNKSFMAQLAAPTS----VTSSAARPSS 176          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Celegans
Match: pax-2 (PAX (Paired box) transcription factor [Source:UniProtKB/TrEMBL;Acc:U4PCL3])

HSP 1 Score: 162.54 bits (410), Expect = 2.667e-45
Identity = 83/151 (54.97%), Postives = 110/151 (72.85%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAAASETSDN 873
             +NQ G  F NGRPLP+ +R +I++++    RPCDISRQL VSHGCVSKIL RY  TGS+ PG IGGSKPKV TP +V+ +  YK  NP ++AWEIRQKLIEDQ+C E++ PS+SSINRI+R+K  ++ + A+ +   P  +  +S TS N
Sbjct:   94 GVNQLGGVFVNGRPLPDTIRAQIVEMSQHGTRPCDISRQLKVSHGCVSKILGRYYSTGSVRPGVIGGSKPKVATPRVVECIAGYKRANPTMFAWEIRQKLIEDQICGEENVPSVSSINRIVRNKSFMA-QLATPTSVTPSVARPSSATSQN 243          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Celegans
Match: pax-1 (PAX (Paired box) transcription factor [Source:UniProtKB/TrEMBL;Acc:Q21272])

HSP 1 Score: 137.502 bits (345), Expect = 4.997e-37
Identity = 69/131 (52.67%), Postives = 96/131 (73.28%), Query Frame = 1
Query:  400 NKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            N  +    +NQ G  F NGRPLP E+R +I++L+ +  RPCDISRQL +SHGCVSKIL R+ + G+I PG IGGS+P+VTTP +V+ +R  K ++P I+AWEIR +LI   +C   + PS+SSI+RI+R+K
Sbjct:   57 NSPAKTAEVNQLGGVFVNGRPLPFEMRCKIVELSRQGTRPCDISRQLKISHGCVSKILTRFSENGTIMPGTIGGSRPRVTTPKVVEYIRSLKRSDPGIFAWEIRDRLISADICDRANLPSVSSISRILRNK 187          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Celegans
Match: vab-3 (MAB-18 [Source:UniProtKB/TrEMBL;Acc:G5EE71])

HSP 1 Score: 137.117 bits (344), Expect = 4.753e-35
Identity = 67/122 (54.92%), Postives = 90/122 (73.77%), Query Frame = 1
Query:  424 INQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRD 789
            +NQ G  F NGRPLP+  R  I+ LA +  RPCDISR L VS+GCVSKIL RY ++G+I P  IGGSKP+V T D+V+++  YK + P I+AWEIR KL+ D +C  ++ PS+SSINR++R+
Sbjct:    9 VNQLGGVFVNGRPLPDATRQRIVDLAHKGCRPCDISRLLQVSNGCVSKILCRYYESGTIRPRAIGGSKPRVATSDVVEKIEDYKRDQPSIFAWEIRDKLLADNICNNETIPSVSSINRVLRN 130          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Fly
Match: sv (gene:FBgn0005561 transcript:FBtr0301563)

HSP 1 Score: 152.525 bits (384), Expect = 2.695e-40
Identity = 75/136 (55.15%), Postives = 99/136 (72.79%), Query Frame = 1
Query:  385 NQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            NQ ++   +    +NQ G  F NGRPLP+ +R  I++LA   VRPCDISRQL VSHGCVSKIL+RY +TGS   G IGGSKPKV TP +VD +  YK  NP ++AWEIR +L+ + +C++ + PS+SSINRI+R+K
Sbjct:   10 NQNMMEYYTCHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNK 145          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Fly
Match: sv (gene:FBgn0005561 transcript:FBtr0089328)

HSP 1 Score: 152.91 bits (385), Expect = 1.122e-39
Identity = 77/141 (54.61%), Postives = 103/141 (73.05%), Query Frame = 1
Query:  370 EKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            E + ++Q  I+   +G  +NQ G  F NGRPLP+ +R  I++LA   VRPCDISRQL VSHGCVSKIL+RY +TGS   G IGGSKPKV TP +VD +  YK  NP ++AWEIR +L+ + +C++ + PS+SSINRI+R+K
Sbjct:  162 EDSHSSQGSISGDGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNK 301          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Fly
Match: sv (gene:FBgn0005561 transcript:FBtr0100345)

HSP 1 Score: 152.525 bits (384), Expect = 1.351e-39
Identity = 77/141 (54.61%), Postives = 103/141 (73.05%), Query Frame = 1
Query:  370 EKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            E + ++Q  I+   +G  +NQ G  F NGRPLP+ +R  I++LA   VRPCDISRQL VSHGCVSKIL+RY +TGS   G IGGSKPKV TP +VD +  YK  NP ++AWEIR +L+ + +C++ + PS+SSINRI+R+K
Sbjct:  162 EDSHSSQGSISGDGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNK 301          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Fly
Match: sv (gene:FBgn0005561 transcript:FBtr0100342)

HSP 1 Score: 153.295 bits (386), Expect = 1.396e-39
Identity = 77/141 (54.61%), Postives = 103/141 (73.05%), Query Frame = 1
Query:  370 EKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            E + ++Q  I+   +G  +NQ G  F NGRPLP+ +R  I++LA   VRPCDISRQL VSHGCVSKIL+RY +TGS   G IGGSKPKV TP +VD +  YK  NP ++AWEIR +L+ + +C++ + PS+SSINRI+R+K
Sbjct:  162 EDSHSSQGSISGDGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNK 301          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Fly
Match: sv (gene:FBgn0005561 transcript:FBtr0089327)

HSP 1 Score: 153.295 bits (386), Expect = 2.703e-39
Identity = 77/141 (54.61%), Postives = 103/141 (73.05%), Query Frame = 1
Query:  370 EKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            E + ++Q  I+   +G  +NQ G  F NGRPLP+ +R  I++LA   VRPCDISRQL VSHGCVSKIL+RY +TGS   G IGGSKPKV TP +VD +  YK  NP ++AWEIR +L+ + +C++ + PS+SSINRI+R+K
Sbjct:  162 EDSHSSQGSISGDGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNK 301          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Zebrafish
Match: pax5 (paired box 5 [Source:ZFIN;Acc:ZDB-GENE-001030-2])

HSP 1 Score: 162.155 bits (409), Expect = 2.013e-44
Identity = 94/195 (48.21%), Postives = 125/195 (64.10%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK--------GIVSIESASNSDKNPICSAAASE---TSDNINGKLELSVNSDT 912
            M L++   + +I      G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ ++VC   S PS+SSINRIIR K        G VS  + +++      SA  S+   +S +I+G L +S  +D 
Sbjct:    1 MDLDQKGPSLRIGRSGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAERVCDNDSVPSVSSINRIIRTKVQQPPGQSGAVSAHNLASTVAVTQVSAVTSDAAGSSYSISGILGISSPADA 193          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Zebrafish
Match: pax5 (paired box 5 [Source:ZFIN;Acc:ZDB-GENE-001030-2])

HSP 1 Score: 159.844 bits (403), Expect = 1.279e-43
Identity = 90/175 (51.43%), Postives = 117/175 (66.86%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK--------GIVSIESASNSDKNPICSAAASE---TSDNINGKLELSVNSDT 912
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ ++VC   S PS+SSINRIIR K        G VS  + +++      SA  S+   +S +I+G L +S  +D 
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAERVCDNDSVPSVSSINRIIRTKVQQPPGQSGAVSAHNLASTVAVTQVSAVTSDAAGSSYSISGILGISSPADA 192          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Zebrafish
Match: pax2a (paired box 2a [Source:NCBI gene;Acc:30425])

HSP 1 Score: 156.762 bits (395), Expect = 1.559e-43
Identity = 79/144 (54.86%), Postives = 101/144 (70.14%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAA 852
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ + VC   + PS+SSINRIIR K       +S+    P+ +A 
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFHPSSDGTGTPLSTAG 161          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Zebrafish
Match: pax2a (paired box 2a [Source:NCBI gene;Acc:30425])

HSP 1 Score: 158.303 bits (399), Expect = 3.362e-43
Identity = 79/144 (54.86%), Postives = 101/144 (70.14%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAA 852
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ + VC   + PS+SSINRIIR K       +S+    P+ +A 
Sbjct:    8 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFHPSSDGTGTPLSTAG 151          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Zebrafish
Match: pax2a (paired box 2a [Source:NCBI gene;Acc:30425])

HSP 1 Score: 158.303 bits (399), Expect = 3.873e-43
Identity = 79/144 (54.86%), Postives = 101/144 (70.14%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAA 852
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ + VC   + PS+SSINRIIR K       +S+    P+ +A 
Sbjct:    8 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFHPSSDGTGTPLSTAG 151          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Xenopus
Match: mfsd4a (major facilitator superfamily domain containing 4A [Source:Xenbase;Acc:XB-GENE-489846])

HSP 1 Score: 158.688 bits (400), Expect = 4.917e-43
Identity = 78/135 (57.78%), Postives = 98/135 (72.59%), Query Frame = 1
Query:  388 QKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             ++   AS    +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ + +C   + PS+SSINRIIR K
Sbjct:    1 HQLPETASRHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTK 135          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Xenopus
Match: igkv7-3 (immunoglobulin kappa variable 7-3 (pseudogene) [Source:Xenbase;Acc:XB-GENE-5762973])

HSP 1 Score: 156.762 bits (395), Expect = 1.782e-42
Identity = 78/140 (55.71%), Postives = 102/140 (72.86%), Query Frame = 1
Query:  373 KNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            K+  +  +  +  +G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    3 KHSKHSNVAYRTRHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Xenopus
Match: mfsd4a (major facilitator superfamily domain containing 4A [Source:Xenbase;Acc:XB-GENE-489846])

HSP 1 Score: 156.762 bits (395), Expect = 2.741e-42
Identity = 76/124 (61.29%), Postives = 94/124 (75.81%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ + +C   + PS+SSINRIIR K
Sbjct:   19 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Xenopus
Match: igkv7-3 (immunoglobulin kappa variable 7-3 (pseudogene) [Source:Xenbase;Acc:XB-GENE-5762973])

HSP 1 Score: 155.606 bits (392), Expect = 3.581e-42
Identity = 76/124 (61.29%), Postives = 95/124 (76.61%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:   14 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 137          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Xenopus
Match: mfsd4a (major facilitator superfamily domain containing 4A [Source:Xenbase;Acc:XB-GENE-489846])

HSP 1 Score: 157.532 bits (397), Expect = 4.966e-42
Identity = 76/124 (61.29%), Postives = 94/124 (75.81%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ + +C   + PS+SSINRIIR K
Sbjct:   19 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Mouse
Match: Pax5 (paired box 5 [Source:MGI Symbol;Acc:MGI:97489])

HSP 1 Score: 161.77 bits (408), Expect = 2.548e-45
Identity = 83/144 (57.64%), Postives = 103/144 (71.53%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    + I     G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTIRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Mouse
Match: Pax5 (paired box 5 [Source:MGI Symbol;Acc:MGI:97489])

HSP 1 Score: 162.155 bits (409), Expect = 3.385e-45
Identity = 83/144 (57.64%), Postives = 103/144 (71.53%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    + I     G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTIRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Mouse
Match: Pax5 (paired box 5 [Source:MGI Symbol;Acc:MGI:97489])

HSP 1 Score: 162.155 bits (409), Expect = 3.675e-45
Identity = 83/144 (57.64%), Postives = 103/144 (71.53%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    + I     G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTIRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Mouse
Match: Pax5 (paired box 5 [Source:MGI Symbol;Acc:MGI:97489])

HSP 1 Score: 162.155 bits (409), Expect = 4.416e-45
Identity = 83/144 (57.64%), Postives = 103/144 (71.53%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    + I     G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTIRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Mouse
Match: Pax5 (paired box 5 [Source:MGI Symbol;Acc:MGI:97489])

HSP 1 Score: 162.925 bits (411), Expect = 5.491e-45
Identity = 83/144 (57.64%), Postives = 103/144 (71.53%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    + I     G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTIRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. UniProt/SwissProt
Match: sp|Q02650|PAX5_MOUSE (Paired box protein Pax-5 OS=Mus musculus OX=10090 GN=Pax5 PE=1 SV=1)

HSP 1 Score: 162.925 bits (411), Expect = 6.137e-44
Identity = 83/144 (57.64%), Postives = 103/144 (71.53%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    + I     G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTIRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. UniProt/SwissProt
Match: sp|Q02548|PAX5_HUMAN (Paired box protein Pax-5 OS=Homo sapiens OX=9606 GN=PAX5 PE=1 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 6.134e-43
Identity = 82/144 (56.94%), Postives = 102/144 (70.83%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LEKN    +       G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:    1 MDLEKNYPTPRTSRTGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. UniProt/SwissProt
Match: sp|Q9YH95|PAX5_XENLA (Paired box protein Pax-5 OS=Xenopus laevis OX=8355 GN=pax5 PE=2 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 6.735e-42
Identity = 77/124 (62.10%), Postives = 95/124 (76.61%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ ++VC   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. UniProt/SwissProt
Match: sp|Q90268|PAX2A_DANRE (Paired box protein Pax-2a OS=Danio rerio OX=7955 GN=pax2a PE=2 SV=2)

HSP 1 Score: 157.918 bits (398), Expect = 7.523e-42
Identity = 79/144 (54.86%), Postives = 101/144 (70.14%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAA 852
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ + VC   + PS+SSINRIIR K       +S+    P+ +A 
Sbjct:   22 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFHPSSDGTGTPLSTAG 165          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. UniProt/SwissProt
Match: sp|P32114|PAX2_MOUSE (Paired box protein Pax-2 OS=Mus musculus OX=10090 GN=Pax2 PE=1 SV=2)

HSP 1 Score: 155.992 bits (393), Expect = 4.179e-41
Identity = 76/124 (61.29%), Postives = 94/124 (75.81%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ + +C   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. TrEMBL
Match: D5SHI2 (Pax-beta2 paired domain protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 243.432 bits (620), Expect = 1.759e-75
Identity = 128/128 (100.00%), Postives = 128/128 (100.00%), Query Frame = 1
Query:  412 NGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKG 795
            NGQNINQYGRCFTNGRPLPEELRLEILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKG
Sbjct:    1 NGQNINQYGRCFTNGRPLPEELRLEILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKG 128          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. TrEMBL
Match: D5SHI1 (Pax-beta1 paired domain protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 196.438 bits (498), Expect = 2.548e-57
Identity = 101/127 (79.53%), Postives = 116/127 (91.34%), Query Frame = 1
Query:  415 GQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKG 795
            GQN+NQYGR FTNGRPLPE+LRL+ILK+AMENVR C+ISRQL VSHGCVSKILNRY +TGSINPGQIGGSKPKVTTP+IV  V+ Y+  NPQI+AWEIRQ+L+++  CTE+SAPSISSINRIIRDKG
Sbjct:    2 GQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRRCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKG 128          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. TrEMBL
Match: D5SHI0 (Pax-beta paired domain protein (Fragment) OS=Lottia gigantea OX=225164 PE=2 SV=1)

HSP 1 Score: 194.897 bits (494), Expect = 9.947e-57
Identity = 99/126 (78.57%), Postives = 115/126 (91.27%), Query Frame = 1
Query:  418 QNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKG 795
            +NINQYGR FTNGRPLPE LR++IL+LA++ +RPC+ISRQL VSHGCVSKILNRY KTGSINPGQIGGSKPKVTTPD+V RVR YK+ NPQ++AWEIRQKLI+D +CTE++ PSISSINRIIRDK 
Sbjct:    3 RNINQYGRQFTNGRPLPEHLRVQILQLALQGIRPCEISRQLQVSHGCVSKILNRYRKTGSINPGQIGGSKPKVTTPDVVSRVRQYKIENPQMFAWEIRQKLIQDGICTEKNIPSISSINRIIRDKA 128          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. TrEMBL
Match: R7TWR1 (Pax-beta paired domain protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_115154 PE=4 SV=1)

HSP 1 Score: 195.282 bits (495), Expect = 1.314e-56
Identity = 99/135 (73.33%), Postives = 119/135 (88.15%), Query Frame = 1
Query:  415 GQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESAS 819
            G+NINQYGR FTNGRPLPE LR++IL+LA++ VRPC+ISRQL VSHGCVSKILNRY KTGSINPGQIGGSKPKVTTPD+V RVR YK+ NPQ++AWEIRQ+L++D +C E++ PSISSINRIIRDK +++    S
Sbjct:    4 GKNINQYGRIFTNGRPLPEHLRVQILQLALQGVRPCEISRQLQVSHGCVSKILNRYRKTGSINPGQIGGSKPKVTTPDVVSRVRQYKIENPQMFAWEIRQRLLDDNICCEKNIPSISSINRIIRDKSLINRRPGS 138          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. TrEMBL
Match: V4B0D1 (Paired domain-containing protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_113393 PE=4 SV=1)

HSP 1 Score: 194.512 bits (493), Expect = 2.540e-56
Identity = 99/125 (79.20%), Postives = 114/125 (91.20%), Query Frame = 1
Query:  424 INQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGI 798
            INQYGR FTNGRPLPE LR++IL+LA++ +RPC+ISRQL VSHGCVSKILNRY KTGSINPGQIGGSKPKVTTPD+V RVR YK+ NPQ++AWEIRQKLI+D +CTE++ PSISSINRIIRDK I
Sbjct:    1 INQYGRQFTNGRPLPEHLRVQILQLALQGIRPCEISRQLQVSHGCVSKILNRYRKTGSINPGQIGGSKPKVTTPDVVSRVRQYKIENPQMFAWEIRQKLIQDGICTEKNIPSISSINRIIRDKAI 125          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Cavefish
Match: pax5 (paired box 5 [Source:NCBI gene;Acc:111195192])

HSP 1 Score: 162.155 bits (409), Expect = 3.114e-44
Identity = 83/144 (57.64%), Postives = 102/144 (70.83%), Query Frame = 1
Query:  361 MKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            M LE+     +I      G  +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ ++VC   S PS+SSINRIIR K
Sbjct:    1 MDLEQKGPAVRIGRSGHGG--VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAERVCDNDSVPSVSSINRIIRTK 142          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Cavefish
Match: pax5 (paired box 5 [Source:NCBI gene;Acc:111195192])

HSP 1 Score: 159.073 bits (401), Expect = 3.724e-43
Identity = 78/124 (62.90%), Postives = 95/124 (76.61%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ ++VC   S PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAERVCDNDSVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Cavefish
Match: pax2a (paired box 2 [Source:NCBI gene;Acc:103046873])

HSP 1 Score: 157.147 bits (396), Expect = 4.795e-43
Identity = 77/124 (62.10%), Postives = 94/124 (75.81%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ + VC   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Cavefish
Match: pax5 (paired box 5 [Source:NCBI gene;Acc:111195192])

HSP 1 Score: 157.918 bits (398), Expect = 5.007e-43
Identity = 78/124 (62.90%), Postives = 95/124 (76.61%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ ++VC   S PS+SSINRIIR K
Sbjct:   40 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAERVCDNDSVPSVSSINRIIRTK 163          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Cavefish
Match: pax2a (paired box 2 [Source:NCBI gene;Acc:103046873])

HSP 1 Score: 154.451 bits (389), Expect = 5.807e-43
Identity = 77/124 (62.10%), Postives = 94/124 (75.81%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ + VC   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Sea Lamprey
Match: pax9 (paired box 9 [Source:ZFIN;Acc:ZDB-GENE-980526-399])

HSP 1 Score: 150.599 bits (379), Expect = 8.176e-43
Identity = 76/123 (61.79%), Postives = 97/123 (78.86%), Query Frame = 1
Query:  424 INQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            +NQ G  F NGRPLP  +RL I+++A   +RPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKP+VTTP++V+ +R YK  +P I+AWEIR KL+ D VC + + PS+SSI+RI+R+K
Sbjct:    7 VNQLGGVFVNGRPLPNAIRLRIVEMAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVNHIRTYKQRDPGIFAWEIRDKLLADGVCDKYNVPSVSSISRILRNK 129          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Sea Lamprey
Match: pax1a (paired box 1a [Source:ZFIN;Acc:ZDB-GENE-070112-182])

HSP 1 Score: 146.747 bits (369), Expect = 3.519e-40
Identity = 76/123 (61.79%), Postives = 96/123 (78.05%), Query Frame = 1
Query:  424 INQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            +NQ G  F NGRPLP  +RL I++LA   +RPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKP+VTTP++V  +R YK  +P I+AWEIR +L+ D VC + + PS+SSI+RI+R+K
Sbjct:   68 VNQLGGVFVNGRPLPNPIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNK 190          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Nematostella
Match: PAXB (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN74])

HSP 1 Score: 152.91 bits (385), Expect = 1.309e-40
Identity = 80/139 (57.55%), Postives = 102/139 (73.38%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNP 837
             +NQ G  F NGRPLP+ +R  I++LA   VRPCDISRQL VSHGCVSKIL R+ +TGSI PG IGGSKPKV T ++V ++  YKL NP ++AWEIR +L+ + VCT  + PS+SSINRI+R++ I S +  SN   NP
Sbjct:   10 GVNQLGGVFVNGRPLPDVVRQRIVELAQSGVRPCDISRQLRVSHGCVSKILCRFYETGSIKPGVIGGSKPKVATGNVVTKIAEYKLANPTMFAWEIRDRLLSEGVCTSDNVPSVSSINRIVRNR-INSQDKMSNPKGNP 147          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Nematostella
Match: PAXC (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCC8])

HSP 1 Score: 151.369 bits (381), Expect = 2.268e-40
Identity = 74/124 (59.68%), Postives = 95/124 (76.61%), Query Frame = 1
Query:  424 INQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKG 795
            +NQ G  F NGRPLP+ +R  I++LA   VRPC+ISR+L VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP I+AWEIR +L+E+ +C   + PS+SSINRI+R+K 
Sbjct:   26 LNQLGGAFVNGRPLPDYIRHRIIQLATYGVRPCEISRRLLVSHGCVSKILGRYYETGSIRPGSIGGSKPKVATPPVVNKILQYKQQNPTIFAWEIRDRLVEEGICDRDNTPSVSSINRILRNKA 149          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Nematostella
Match: PAXA (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S916])

HSP 1 Score: 144.05 bits (362), Expect = 3.797e-37
Identity = 73/122 (59.84%), Postives = 91/122 (74.59%), Query Frame = 1
Query:  424 INQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRD 789
            +NQ G  F NGRPLP+ +R  I++LA   VRP +ISRQL VSHGCVSKIL RY +TGS+ PG IGGSKPKV TP +V ++  YK  NP I+AWEIR  L+ D VC + + PS+SSINRI+R+
Sbjct:    9 VNQLGGVFVNGRPLPDYMRHRIVELAHCGVRPSEISRQLLVSHGCVSKILGRYYETGSVRPGAIGGSKPKVATPKVVSKILEYKDKNPCIFAWEIRNNLLADGVCDKTNVPSVSSINRILRN 130          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Nematostella
Match: EDO36623 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI38])

HSP 1 Score: 120.939 bits (302), Expect = 1.071e-32
Identity = 61/125 (48.80%), Postives = 93/125 (74.40%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSK-PKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP  LR +I++LA   VRPCDISR+L VSHGCVSKIL R+ +TGSI PG I GS  P+  TP+I +++  Y+  NP +++WE+R +L++D VC+  + PS+++I+++++++
Sbjct:    5 RVNQLGGVFINGRPLPLVLRKQIIELAQLGVRPCDISRRLRVSHGCVSKILYRFQQTGSIEPGAIAGSSTPRNVTPEIEEKIDEYRRENPGMFSWEVRDRLVKDNVCSRCTVPSLAAISQVLKNR 129          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Nematostella
Match: EDO32510 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUW0])

HSP 1 Score: 113.235 bits (282), Expect = 5.640e-30
Identity = 54/123 (43.90%), Postives = 88/123 (71.54%), Query Frame = 1
Query:  424 INQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            +NQ G  + NG+PLP E+R++I++LA   VRPC+ISR+L ++HGC+SK+L ++ KTGS+ PG +   +P+V T  I  ++  Y+   P I++WEIR +L+++ +C     PS+SSI+RI++ K
Sbjct:    1 VNQLGGGYVNGKPLPREIRIQIIELARSGVRPCEISRRLKITHGCISKLLAKFQKTGSLEPGTVYKGRPRVVTSQIEKKIDQYRAEQPGIFSWEIRDQLLQEGICDRSEVPSLSSISRIVKRK 123          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Medaka
Match: pax5 (paired box 5 [Source:NCBI gene;Acc:101169910])

HSP 1 Score: 162.925 bits (411), Expect = 9.176e-45
Identity = 90/174 (51.72%), Postives = 118/174 (67.82%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK--------GIVSIESASNS---DKNPICSAAASETSDNINGKLELSVNSD 909
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ ++VC   S PS+SSINRIIR K        G VS  S + S    + P  ++ ++ +S +I+G L +S  +D
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAERVCDNDSVPSVSSINRIIRTKVQQQPGQTGSVSAHSLATSVAASQVPAVTSDSAGSSYSISGILGISSAAD 191          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Medaka
Match: pax5 (paired box 5 [Source:NCBI gene;Acc:101169910])

HSP 1 Score: 161.77 bits (408), Expect = 1.009e-44
Identity = 90/175 (51.43%), Postives = 118/175 (67.43%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK--------GIVSIESASNS---DKNPICSAAASETSDNINGKLELSVNSDT 912
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ ++VC   S PS+SSINRIIR K        G VS  S + S    + P  ++ ++ +S +I+G L +S  +D 
Sbjct:   13 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAERVCDNDSVPSVSSINRIIRTKVQQQPGQTGSVSAHSLATSVAASQVPAVTSDSAGSSYSISGILGISSAADV 187          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Medaka
Match: pax2a (paired box protein Pax-2a [Source:NCBI gene;Acc:101155219])

HSP 1 Score: 156.762 bits (395), Expect = 1.333e-42
Identity = 77/124 (62.10%), Postives = 94/124 (75.81%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +VD++  YK  NP ++AWEIR +L+ + VC   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Medaka
Match: ENSORLT00000038038.1 (paired box 2 [Source:NCBI gene;Acc:100049457])

HSP 1 Score: 153.295 bits (386), Expect = 2.584e-42
Identity = 75/124 (60.48%), Postives = 94/124 (75.81%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ + +C   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIADYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Medaka
Match: ENSORLT00000011688.2 (paired box 2 [Source:NCBI gene;Acc:100049457])

HSP 1 Score: 154.451 bits (389), Expect = 3.938e-42
Identity = 75/124 (60.48%), Postives = 94/124 (75.81%), Query Frame = 1
Query:  421 NINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
             +NQ G  F NGRPLP+ +R  I++LA + VRPCDISRQL VSHGCVSKIL RY +TGSI PG IGGSKPKV TP +V+++  YK  NP ++AWEIR +L+ + +C   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIADYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Planmine SMEST
Match: SMESG000066574.1 (SMESG000066574.1)

HSP 1 Score: 839.721 bits (2168), Expect = 0.000e+0
Identity = 438/438 (100.00%), Postives = 438/438 (100.00%), Query Frame = 1
Query:  199 MSEALQSSLSMHSNLQKIEQTDWIGTDSESTEILDLSHNRKRKTPIKRISSNKKMKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAAASETSDNINGKLELSVNSDTLEEVNNNYKDSVADEDGSNKPNSIWPNVSLTPKIISSENPVNPINLFTNSTPTSWNGIPLSLPILPGFXXXXXXXXXXXXAQSSAFISDLATSSSTFQSWATALIHAQMSLLQYQSTMTSCIGQPLWPGQVHTLLSADEQNNSTCQPIIYVGNNQWQLRSSKTNHKLSIDSLTEKINNDPHEEFVSGTPSRTSTHKSEMH 1512
            MSEALQSSLSMHSNLQKIEQTDWIGTDSESTEILDLSHNRKRKTPIKRISSNKKMKLEKNDNNQKIINKASNGQNINQYGRCFTNGRPLPEELRLEILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAAASETSDNINGKLELSVNSDTLEEVNNNYKDSVADEDGSNKPNSIWPNVSLTPKIISSENPVNPINLFTNSTPTSWNGIPLSLPILPGFPSLTPLSQPPSTAQSSAFISDLATSSSTFQSWATALIHAQMSLLQYQSTMTSCIGQPLWPGQVHTLLSADEQNNSTCQPIIYVGNNQWQLRSSKTNHKLSIDSLTEKINNDPHEEFVSGTPSRTSTHKSEMH
Sbjct:    1 MSEALQSSLSMHSNLQKIEQTDWIGTDSESTEILDLSHNRKRKTPIKRISSNKKMKLEKNDNNQKIINKASNGQNINQYGRCFTNGRPLPEELRLEILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAAASETSDNINGKLELSVNSDTLEEVNNNYKDSVADEDGSNKPNSIWPNVSLTPKIISSENPVNPINLFTNSTPTSWNGIPLSLPILPGFPSLTPLSQPPSTAQSSAFISDLATSSSTFQSWATALIHAQMSLLQYQSTMTSCIGQPLWPGQVHTLLSADEQNNSTCQPIIYVGNNQWQLRSSKTNHKLSIDSLTEKINNDPHEEFVSGTPSRTSTHKSEMH 438          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Planmine SMEST
Match: SMESG000080212.1 (SMESG000080212.1)

HSP 1 Score: 266.929 bits (681), Expect = 2.507e-83
Identity = 167/348 (47.99%), Postives = 213/348 (61.21%), Query Frame = 1
Query:  403 KASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAAASETSDNINGKLELSVNSDTLEEVNNNYKDSVADEDGSNKPNSIWPNVSLTPKIISSE----NPVNPINLFT-NSTPTSWNGIPLSLPILPGFXXXXXXXXXXXXAQSSAFISDLATSSSTFQSWATALIHAQMSLLQYQSTMTSCIGQPLWPGQVHTLLSAD------------EQNNSTCQPIIYVGNNQWQLRSS 1395
            +A  GQN+NQYGR FTNGRPLPE+LRL+ILK+AMENVRPC+ISRQL VSHGCVSKILNRY +TGSINPGQIGGSKPKVTTP+IV  V+ Y+  NPQI+AWEIRQ+L+++  CTE+SAPSISSINRIIRDKGI +             S+       +I     LS +SD     NNN  D + +E  S K +S   + +L  +  +SE    + +  +   T NS+P+    I   L  + G           S  Q          S     +W  A+I AQ++LLQY S   SC+GQ LWPGQVHTL+  D              +  +C+P++Y+GNNQWQL+SS
Sbjct:  124 RAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKT-------------SSVGRIDEGDIKQLESLSAHSDGSVMSNNNSSDRMLNESDSTKQHSEIVDTNLVKQERNSEIVSNDEIPDVECGTLNSSPS----IKEELSKMDGMGITGVNQTIMSLWQQQMMTQHPTGSI----NWGQAVIAAQLALLQYHS--LSCLGQTLWPGQVHTLIETDTLCSDSSEPHNIRPDKVSCRPMVYIGNNQWQLKSS 448          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Planmine SMEST
Match: SMESG000080212.1 (SMESG000080212.1)

HSP 1 Score: 266.544 bits (680), Expect = 3.144e-83
Identity = 167/348 (47.99%), Postives = 213/348 (61.21%), Query Frame = 1
Query:  403 KASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAAASETSDNINGKLELSVNSDTLEEVNNNYKDSVADEDGSNKPNSIWPNVSLTPKIISSE----NPVNPINLFT-NSTPTSWNGIPLSLPILPGFXXXXXXXXXXXXAQSSAFISDLATSSSTFQSWATALIHAQMSLLQYQSTMTSCIGQPLWPGQVHTLLSAD------------EQNNSTCQPIIYVGNNQWQLRSS 1395
            +A  GQN+NQYGR FTNGRPLPE+LRL+ILK+AMENVRPC+ISRQL VSHGCVSKILNRY +TGSINPGQIGGSKPKVTTP+IV  V+ Y+  NPQI+AWEIRQ+L+++  CTE+SAPSISSINRIIRDKGI +             S+       +I     LS +SD     NNN  D + +E  S K +S   + +L  +  +SE    + +  +   T NS+P+    I   L  + G           S  Q          S     +W  A+I AQ++LLQY S   SC+GQ LWPGQVHTL+  D              +  +C+P++Y+GNNQWQL+SS
Sbjct:  119 RAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKT-------------SSVGRIDEGDIKQLESLSAHSDGSVMSNNNSSDRMLNESDSTKQHSEIVDTNLVKQERNSEIVSNDEIPDVECGTLNSSPS----IKEELSKMDGMGITGVNQTIMSLWQQQMMTQHPTGSI----NWGQAVIAAQLALLQYHS--LSCLGQTLWPGQVHTLIETDTLCSDSSEPHNIRPDKVSCRPMVYIGNNQWQLKSS 443          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Planmine SMEST
Match: SMESG000004009.1 (SMESG000004009.1)

HSP 1 Score: 161.77 bits (408), Expect = 8.352e-43
Identity = 83/161 (51.55%), Postives = 115/161 (71.43%), Query Frame = 1
Query:  310 HNRKRKTPIKRISSNKKMKLEKNDNNQKIINKASNGQNINQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDK 792
            H + ++  IK    +KK+ L +++N +   N  +    +NQ G  F NGRPLP  +R +I++LA   VRPCDISRQL VSHGCVSKIL R+ +TGSI PG IGGSKPKV TP++V+ +  YK  NP ++AWEIR  L+ D+VC++++ PS+SSINRI+R+K
Sbjct:   20 HKKMKRPNIK----SKKLHLPESENGKLKTNDINGHGGVNQLGGLFVNGRPLPNSVRQQIVELAHRGVRPCDISRQLRVSHGCVSKILGRFYETGSIKPGVIGGSKPKVATPEVVEAICKYKAENPTMFAWEIRDMLLNDRVCSQENVPSVSSINRIVRNK 176          
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Planmine SMEST
Match: SMESG000077501.1 (SMESG000077501.1)

HSP 1 Score: 141.739 bits (356), Expect = 4.198e-36
Identity = 77/137 (56.20%), Postives = 96/137 (70.07%), Query Frame = 1
Query:  379 DNNQKIINKASNGQN-INQYGRCFTNGXXXXXXXXXXILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIR 786
            D N KI  K   G + INQ G  F NGRPLP+  R  I++L+    RPCDISR L VS+GCVSKIL RY +TGSI P  IGGSKP+V T  +V +V IYK  +P ++AWEIR +L++D VC + + PSISSINRI+R
Sbjct:    8 DENMKINRKLRKGHSGINQLGGMFVNGRPLPDMTRQRIIELSQSGARPCDISRILQVSNGCVSKILCRYYETGSIKPKAIGGSKPRVATNTVVRKVTIYKQESPSMFAWEIRDRLLQDGVCNQDNLPSISSINRILR 144          
The following BLAST results are available for this feature:
BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PAX54.043e-4456.94paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619][more]
PAX54.498e-4456.94paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619][more]
PAX54.927e-4456.94paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619][more]
PAX55.634e-4456.94paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619][more]
PAX56.820e-4456.94paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619][more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pax-23.037e-4654.97PAX (Paired box) transcription factor [Source:Uni... [more]
egl-384.894e-4655.03PAX protein [Source:UniProtKB/TrEMBL;Acc:G5ED14][more]
pax-22.667e-4554.97PAX (Paired box) transcription factor [Source:Uni... [more]
pax-14.997e-3752.67PAX (Paired box) transcription factor [Source:Uni... [more]
vab-34.753e-3554.92MAB-18 [Source:UniProtKB/TrEMBL;Acc:G5EE71][more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sv2.695e-4055.15gene:FBgn0005561 transcript:FBtr0301563[more]
sv1.122e-3954.61gene:FBgn0005561 transcript:FBtr0089328[more]
sv1.351e-3954.61gene:FBgn0005561 transcript:FBtr0100345[more]
sv1.396e-3954.61gene:FBgn0005561 transcript:FBtr0100342[more]
sv2.703e-3954.61gene:FBgn0005561 transcript:FBtr0089327[more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pax52.013e-4448.21paired box 5 [Source:ZFIN;Acc:ZDB-GENE-001030-2][more]
pax51.279e-4351.43paired box 5 [Source:ZFIN;Acc:ZDB-GENE-001030-2][more]
pax2a1.559e-4354.86paired box 2a [Source:NCBI gene;Acc:30425][more]
pax2a3.362e-4354.86paired box 2a [Source:NCBI gene;Acc:30425][more]
pax2a3.873e-4354.86paired box 2a [Source:NCBI gene;Acc:30425][more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mfsd4a4.917e-4357.78major facilitator superfamily domain containing 4A... [more]
igkv7-31.782e-4255.71immunoglobulin kappa variable 7-3 (pseudogene) [So... [more]
mfsd4a2.741e-4261.29major facilitator superfamily domain containing 4A... [more]
igkv7-33.581e-4261.29immunoglobulin kappa variable 7-3 (pseudogene) [So... [more]
mfsd4a4.966e-4261.29major facilitator superfamily domain containing 4A... [more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pax52.548e-4557.64paired box 5 [Source:MGI Symbol;Acc:MGI:97489][more]
Pax53.385e-4557.64paired box 5 [Source:MGI Symbol;Acc:MGI:97489][more]
Pax53.675e-4557.64paired box 5 [Source:MGI Symbol;Acc:MGI:97489][more]
Pax54.416e-4557.64paired box 5 [Source:MGI Symbol;Acc:MGI:97489][more]
Pax55.491e-4557.64paired box 5 [Source:MGI Symbol;Acc:MGI:97489][more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q02650|PAX5_MOUSE6.137e-4457.64Paired box protein Pax-5 OS=Mus musculus OX=10090 ... [more]
sp|Q02548|PAX5_HUMAN6.134e-4356.94Paired box protein Pax-5 OS=Homo sapiens OX=9606 G... [more]
sp|Q9YH95|PAX5_XENLA6.735e-4262.10Paired box protein Pax-5 OS=Xenopus laevis OX=8355... [more]
sp|Q90268|PAX2A_DANRE7.523e-4254.86Paired box protein Pax-2a OS=Danio rerio OX=7955 G... [more]
sp|P32114|PAX2_MOUSE4.179e-4161.29Paired box protein Pax-2 OS=Mus musculus OX=10090 ... [more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
D5SHI21.759e-75100.00Pax-beta2 paired domain protein (Fragment) OS=Schm... [more]
D5SHI12.548e-5779.53Pax-beta1 paired domain protein (Fragment) OS=Schm... [more]
D5SHI09.947e-5778.57Pax-beta paired domain protein (Fragment) OS=Lotti... [more]
R7TWR11.314e-5673.33Pax-beta paired domain protein (Fragment) OS=Capit... [more]
V4B0D12.540e-5679.20Paired domain-containing protein (Fragment) OS=Lot... [more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pax53.114e-4457.64paired box 5 [Source:NCBI gene;Acc:111195192][more]
pax53.724e-4362.90paired box 5 [Source:NCBI gene;Acc:111195192][more]
pax2a4.795e-4362.10paired box 2 [Source:NCBI gene;Acc:103046873][more]
pax55.007e-4362.90paired box 5 [Source:NCBI gene;Acc:111195192][more]
pax2a5.807e-4362.10paired box 2 [Source:NCBI gene;Acc:103046873][more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pax98.176e-4361.79paired box 9 [Source:ZFIN;Acc:ZDB-GENE-980526-399][more]
pax1a3.519e-4061.79paired box 1a [Source:ZFIN;Acc:ZDB-GENE-070112-182... [more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
PAXB1.309e-4057.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
PAXC2.268e-4059.68Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
PAXA3.797e-3759.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO366231.071e-3248.80Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO325105.640e-3043.90Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pax59.176e-4551.72paired box 5 [Source:NCBI gene;Acc:101169910][more]
pax51.009e-4451.43paired box 5 [Source:NCBI gene;Acc:101169910][more]
pax2a1.333e-4262.10paired box protein Pax-2a [Source:NCBI gene;Acc:10... [more]
ENSORLT00000038038.12.584e-4260.48paired box 2 [Source:NCBI gene;Acc:100049457][more]
ENSORLT00000011688.23.938e-4260.48paired box 2 [Source:NCBI gene;Acc:100049457][more]
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BLAST of TPA_inf: Pax-beta2 paired domain protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000066574.10.000e+0100.00SMESG000066574.1[more]
SMESG000080212.12.507e-8347.99SMESG000080212.1[more]
SMESG000080212.13.144e-8347.99SMESG000080212.1[more]
SMESG000004009.18.352e-4351.55SMESG000004009.1[more]
SMESG000077501.14.198e-3656.20SMESG000077501.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30007365
GenBankDAA12514.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007365 ID=SMED30007365|Name=TPA_inf: Pax-beta2 paired domain protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1538bp
CGAACTTAACTCGGTTCGAACAGGTTCAATTAGTCAACTATGAGCTTGTC
ACAATTCAATACTCAATACTGCGTGAGTGACTATATAAACAAGCTAACAA
AGCAGTAGTAATCAATACAGCAGCTTTACGTTTTGTGCGACTGATAATAA
AAATAGTGCTTGAAAACCGAATCGTTAACTGTGTAAAACTTTTACAGAAT
GTCAGAGGCTTTACAATCATCTTTGAGTATGCATTCGAATTTGCAGAAAA
TCGAACAAACAGACTGGATTGGAACTGATTCGGAATCGACGGAAATTTTG
GATTTATCACACAATCGAAAACGCAAAACTCCAATCAAGAGAATTTCCTC
GAATAAGAAAATGAAACTGGAAAAGAATGACAACAATCAGAAAATAATAA
ACAAAGCAAGTAATGGGCAAAACATTAATCAGTATGGTCGATGTTTCACA
AACGGTCGTCCATTGCCGGAGGAATTGAGATTGGAAATTTTGAAGTTAGC
CATGGAAAACGTTCGTCCCTGTGATATTTCCAGACAGTTATGCGTTTCAC
ATGGTTGCGTGAGCAAAATATTGAATAGATACGTTAAAACTGGTTCCATC
AATCCAGGTCAAATCGGTGGCTCAAAACCGAAAGTAACAACTCCAGACAT
CGTTGACAGGGTTCGAATTTACAAATTGAACAATCCACAGATCTATGCCT
GGGAAATCCGTCAGAAATTAATCGAAGATCAAGTGTGCACGGAACAAAGT
GCTCCTAGCATTTCGTCAATAAATCGAATTATTCGCGACAAAGGAATTGT
GTCAATCGAATCTGCATCGAATTCAGATAAAAACCCAATTTGTTCGGCAG
CCGCTTCAGAAACTTCAGACAACATTAATGGGAAATTGGAACTGAGCGTT
AATTCAGATACATTAGAAGAAGTGAACAACAATTATAAAGATTCAGTTGC
TGATGAAGATGGATCTAATAAACCTAACAGTATCTGGCCTAATGTATCGT
TAACTCCAAAAATTATCAGTTCAGAAAATCCAGTAAACCCAATAAACCTC
TTTACTAACTCCACTCCAACATCATGGAATGGGATTCCATTATCTTTGCC
CATTTTACCAGGATTTCCTTCATTAACACCTCTTTCACAGCCTCCTTCAA
CCGCTCAATCAAGTGCATTCATTTCTGATCTCGCCACCTCATCAAGCACA
TTTCAGTCATGGGCTACTGCTTTAATACACGCGCAAATGTCTTTATTACA
ATATCAATCAACTATGACCTCATGCATAGGTCAACCGCTATGGCCGGGTC
AAGTGCATACACTATTAAGTGCCGATGAACAGAATAATTCTACCTGTCAA
CCGATAATTTATGTAGGCAATAATCAGTGGCAGTTGAGATCGTCAAAAAC
CAATCACAAATTATCAATTGATTCTTTAACAGAAAAAATTAATAATGATC
CCCATGAAGAATTTGTCAGTGGCACCCCTTCCAGAACTTCAACACATAAA
TCAGAGATGCATTAATTTTATTAATTTTTTTATTATTA
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protein sequence of SMED30007365-orf-1

>SMED30007365-orf-1 ID=SMED30007365-orf-1|Name=SMED30007365-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=439bp
MSEALQSSLSMHSNLQKIEQTDWIGTDSESTEILDLSHNRKRKTPIKRIS
SNKKMKLEKNDNNQKIINKASNGQNINQYGRCFTNGRPLPEELRLEILKL
AMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPD
IVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGI
VSIESASNSDKNPICSAAASETSDNINGKLELSVNSDTLEEVNNNYKDSV
ADEDGSNKPNSIWPNVSLTPKIISSENPVNPINLFTNSTPTSWNGIPLSL
PILPGFPSLTPLSQPPSTAQSSAFISDLATSSSTFQSWATALIHAQMSLL
QYQSTMTSCIGQPLWPGQVHTLLSADEQNNSTCQPIIYVGNNQWQLRSSK
TNHKLSIDSLTEKINNDPHEEFVSGTPSRTSTHKSEMH*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR036388WH-like_DNA-bd_sf
IPR043182PAIRED_DNA_bd_dom
IPR001523Paired_dom
IPR011991WHTH_DNA-bd_dom
IPR009057Homeobox-like_sf
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO:0006351transcription, DNA-templated
GO:0007275multicellular organism development
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001523Paired domainPRINTSPR00027PAIREDBOXcoord: 76..91
score: 62.71
coord: 114..131
score: 74.78
coord: 94..112
score: 58.13
coord: 132..149
score: 74.59
IPR001523Paired domainSMARTSM00351pax3coord: 72..196
e-value: 1.1E-73
score: 260.8
IPR001523Paired domainPFAMPF00292PAXcoord: 75..196
e-value: 5.1E-54
score: 181.5
IPR001523Paired domainPROSITEPS51057PAIRED_2coord: 72..198
score: 51.178
IPR036388Winged helix-like DNA-binding domain superfamilyGENE3DG3DSA:1.10.10.10coord: 141..202
e-value: 6.5E-27
score: 95.0
IPR036388Winged helix-like DNA-binding domain superfamilyGENE3DG3DSA:1.10.10.10coord: 71..140
e-value: 2.4E-31
score: 109.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 416..438
NoneNo IPR availablePANTHERPTHR45636:SF7PAIRED BOX POX-NEURO PROTEIN-RELATEDcoord: 50..415
NoneNo IPR availablePANTHERPTHR45636FAMILY NOT NAMEDcoord: 50..415
IPR043182Paired DNA-binding domainPROSITEPS00034PAIRED_1coord: 106..122
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 75..199