Serine/threonine-protein phosphatase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30007351 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Match: PPEF1 (protein phosphatase with EF-hand domain 1 [Source:HGNC Symbol;Acc:HGNC:9243]) HSP 1 Score: 182.956 bits (463), Expect = 3.938e-52 Identity = 105/252 (41.67%), Postives = 150/252 (59.52%), Query Frame = 2
Query: 119 ATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIP-WADIDALDA--SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEI--SPV-SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQ 850
+L+A L+IQ +YR Y+A+ +A++ I Q +EY++EQ Q+ + S L N H K + N L ++ W +D++D S+NG +L++P+T + L+E +K L ++E+L + VL+ +PN I SP +TICGD+HG DDL IF KN LPS NPY+FNGDFVDRG S+E++ +L V FL PN + LNRGNHED MN RYGF KE+ +KYK K +LQ
Sbjct: 15 TSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLSTFFSFMLENYTHIH---KEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKE-QQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQ 262
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Match: PPEF1 (protein phosphatase with EF-hand domain 1 [Source:HGNC Symbol;Acc:HGNC:9243]) HSP 1 Score: 182.57 bits (462), Expect = 1.739e-51 Identity = 105/252 (41.67%), Postives = 150/252 (59.52%), Query Frame = 2
Query: 119 ATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIP-WADIDALDA--SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEI--SPV-SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQ 850
+L+A L+IQ +YR Y+A+ +A++ I Q +EY++EQ Q+ + S L N H K + N L ++ W +D++D S+NG +L++P+T + L+E +K L ++E+L + VL+ +PN I SP +TICGD+HG DDL IF KN LPS NPY+FNGDFVDRG S+E++ +L V FL PN + LNRGNHED MN RYGF KE+ +KYK K +LQ
Sbjct: 15 TSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLSTFFSFMLENYTHIH---KEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKE-QQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQ 262 HSP 2 Score: 59.6918 bits (143), Expect = 3.373e-9 Identity = 25/38 (65.79%), Postives = 30/38 (78.95%), Query Frame = 3
Query: 930 HHRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
H + Q++++LWSDPR NGC NT RGGGCYFGPDVT
Sbjct: 350 EHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVT 387
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Match: PPEF2 (protein phosphatase with EF-hand domain 2 [Source:HGNC Symbol;Acc:HGNC:9244]) HSP 1 Score: 174.866 bits (442), Expect = 5.683e-49 Identity = 98/248 (39.52%), Postives = 137/248 (55.24%), Query Frame = 2
Query: 110 NIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITL-HNNPERHFDVKCKFSKFN-DILPPDKQAIPWADIDALDA--SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
N KA LIQ++YRRY A+ E +R+ W I Q +EY+ +Q+Q+ + S + H P H D F D D + +D ++++ S+ G +L +P+ LVE ++ +L R ++ LL + L LPN+ +S IT+CGD+HG DDL+ IF KN LPS Y+FNGDFVDRG SVE++ +L L P LNRGNHEDH +N RYGF KE+ NKYK
Sbjct: 15 NAERAFKAAALIQRWYRRYVARLEMRRRCTWSIFQSIEYAGQQDQVKLHDFFSYLMDHFIPSSHNDRDFLTRIFTEDRFAQDSEMKKCSDYESIEVPDSYTGPRLSFPLLPDHATALVEAFRL-KQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYK 261 HSP 2 Score: 60.077 bits (144), Expect = 2.856e-9 Identity = 24/33 (72.73%), Postives = 27/33 (81.82%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
QV+++LWSDP GCK NT RGGGCYFGPDVT
Sbjct: 440 QVVDILWSDPMAQEGCKANTIRGGGCYFGPDVT 472
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Match: PPEF2 (protein phosphatase with EF-hand domain 2 [Source:HGNC Symbol;Acc:HGNC:9244]) HSP 1 Score: 174.481 bits (441), Expect = 3.668e-48 Identity = 98/248 (39.52%), Postives = 137/248 (55.24%), Query Frame = 2
Query: 110 NIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITL-HNNPERHFDVKCKFSKFN-DILPPDKQAIPWADIDALDA--SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
N KA LIQ++YRRY A+ E +R+ W I Q +EY+ +Q+Q+ + S + H P H D F D D + +D ++++ S+ G +L +P+ LVE ++ +L R ++ LL + L LPN+ +S IT+CGD+HG DDL+ IF KN LPS Y+FNGDFVDRG SVE++ +L L P LNRGNHEDH +N RYGF KE+ NKYK
Sbjct: 15 NAERAFKAAALIQRWYRRYVARLEMRRRCTWSIFQSIEYAGQQDQVKLHDFFSYLMDHFIPSSHNDRDFLTRIFTEDRFAQDSEMKKCSDYESIEVPDSYTGPRLSFPLLPDHATALVEAFRL-KQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYK 261 HSP 2 Score: 62.003 bits (149), Expect = 7.292e-10 Identity = 24/33 (72.73%), Postives = 27/33 (81.82%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
QV+++LWSDP GCK NT RGGGCYFGPDVT
Sbjct: 440 QVVDILWSDPMAQEGCKANTIRGGGCYFGPDVT 472
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Match: PPEF1 (protein phosphatase with EF-hand domain 1 [Source:HGNC Symbol;Acc:HGNC:9243]) HSP 1 Score: 124.405 bits (311), Expect = 7.688e-34 Identity = 64/110 (58.18%), Postives = 76/110 (69.09%), Query Frame = 2
Query: 536 LPNVYEI--SPV-SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQ 850
+PN I SP +TICGD+HG DDL IF KN LPS NPY+FNGDFVDRG S+E++ +L V FL PN + LNRGNHED MN RYGF KE+ +KYK K +LQ
Sbjct: 1 MPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQ 110
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Match: pef-1 (Serine/threonine-protein phosphatase with EF-hands pef-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EBX9]) HSP 1 Score: 175.252 bits (443), Expect = 2.828e-49 Identity = 98/286 (34.27%), Postives = 154/286 (53.85%), Query Frame = 2
Query: 38 MGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIPWADIDA------------------LDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
MGC SS + N + ++ T+K+ +LIQK+YRR A+ EA+R+ W+I +EY+ EQ+Q+ + + + E + + + + ++ + +D+ +D ++ G L P+ V ++E +K N L + ++ +L A+ + + +P+V IS +TICGD+HG FDDL I KN PS NPY+FNGDFVDRG +S+EV+ VL + +P +++LNRGNHEDH MN RYGF KEL+ KYK
Sbjct: 1 MGCGPSSG--RQNPSTEL----------TIKSAILIQKWYRRCEARLEARRRATWQIFTALEYAGEQDQLKLYDFFADVIRAMAEENGKGGVENGRNSPLMSALSHYAKPSLMDSEGETVKKMLEDTSPTNVDIDRNYKGPTLSLPLDKPQVAKMIEAFKV-NKVLHPKYVLMILHEARKIFKAMPSVSRISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIVDPMSIYLNRGNHEDHIMNLRYGFIKELSTKYK 273 HSP 2 Score: 47.7506 bits (112), Expect = 9.869e-6 Identity = 18/33 (54.55%), Postives = 25/33 (75.76%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q+L+++WSDP+ GC N +RGGG YFG D+T
Sbjct: 352 QMLDIMWSDPKQNKGCWPNVFRGGGSYFGADIT 384
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Match: pef-1 (Serine/threonine-protein phosphatase with EF-hands pef-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EBX9]) HSP 1 Score: 173.326 bits (438), Expect = 2.165e-48 Identity = 92/258 (35.66%), Postives = 144/258 (55.81%), Query Frame = 2
Query: 122 TLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIPWADIDA------------------LDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
T+K+ +LIQK+YRR A+ EA+R+ W+I +EY+ EQ+Q+ + + + E + + + + ++ + +D+ +D ++ G L P+ V ++E +K N L + ++ +L A+ + + +P+V IS +TICGD+HG FDDL I KN PS NPY+FNGDFVDRG +S+EV+ VL + +P +++LNRGNHEDH MN RYGF KEL+ KYK
Sbjct: 82 TIKSAILIQKWYRRCEARLEARRRATWQIFTALEYAGEQDQLKLYDFFADVIRAMAEENGKGGVENGRNSPLMSALSHYAKPSLMDSEGETVKKMLEDTSPTNVDIDRNYKGPTLSLPLDKPQVAKMIEAFKV-NKVLHPKYVLMILHEARKIFKAMPSVSRISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIVDPMSIYLNRGNHEDHIMNLRYGFIKELSTKYK 338 HSP 2 Score: 50.0618 bits (118), Expect = 1.676e-6 Identity = 18/33 (54.55%), Postives = 25/33 (75.76%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q+L+++WSDP+ GC N +RGGG YFG D+T
Sbjct: 417 QMLDIMWSDPKQNKGCWPNVFRGGGSYFGADIT 449
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Match: pef-1 (Serine/threonine-protein phosphatase with EF-hands pef-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EBX9]) HSP 1 Score: 144.05 bits (362), Expect = 2.616e-38 Identity = 70/153 (45.75%), Postives = 98/153 (64.05%), Query Frame = 2
Query: 383 LDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
+D ++ G L P+ V ++E +K N L + ++ +L A+ + + +P+V IS +TICGD+HG FDDL I KN PS NPY+FNGDFVDRG +S+EV+ VL + +P +++LNRGNHEDH MN RYGF KEL+ KYK
Sbjct: 52 IDRNYKGPTLSLPLDKPQVAKMIEAFKV-NKVLHPKYVLMILHEARKIFKAMPSVSRISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIVDPMSIYLNRGNHEDHIMNLRYGFIKELSTKYK 203 HSP 2 Score: 47.7506 bits (112), Expect = 9.717e-6 Identity = 18/33 (54.55%), Postives = 25/33 (75.76%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q+L+++WSDP+ GC N +RGGG YFG D+T
Sbjct: 282 QMLDIMWSDPKQNKGCWPNVFRGGGSYFGADIT 314
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Match: pph-5 (Serine/threonine-protein phosphatase 5 [Source:UniProtKB/Swiss-Prot;Acc:Q9NES8]) HSP 1 Score: 122.865 bits (307), Expect = 4.652e-31 Identity = 68/153 (44.44%), Postives = 94/153 (61.44%), Query Frame = 2
Query: 380 ALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEIS-PVS--ITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKY 829
A++ S++G +L+ IT + V L++ +K+ KL + ++LL ++ LP + EI+ P TICGD+HG F DL IF+ N PS +NPYLFNGDFVDRGS SVE I ++ L PN F++RGNHE MN YGF E+ KY
Sbjct: 171 AIEDSYDGPRLEDKITKEFVLQLIKTFKN-QQKLHKKYAFKMLLEFYNYVKSLPTMVEITVPTGKKFTICGDVHGQFYDLCNIFEINGYPSETNPYLFNGDFVDRGSFSVETIFTMIGFKLLYPNHFFMSRGNHESDVMNKMYGFEGEVKAKY 322
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Match: Y71G12B.30 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:Q4W5Q9]) HSP 1 Score: 98.9821 bits (245), Expect = 2.542e-23 Identity = 61/160 (38.12%), Postives = 88/160 (55.00%), Query Frame = 2
Query: 401 GFKLKYPITSKIVRNLVEFYKSGNNK--LSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNP-----YLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQYES 859
G L +T+ I R L + + GN + +++IE+ RA+ P EI +TICGDIHG F+DL+++F P S YLF GD++DRG S+EVI++L L +P +FL RGNHE +N +YGF+ E +Y SV YE+
Sbjct: 9 GSPLHRKLTNVIFR-LTQSWSPGNCQTLFQEKEIIEICYRAREAFWKEPMKLEIE-APVTICGDIHGQFEDLLSMFDIYGFPHVSQKDKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGNHESRPVNMQYGFYNECKRRY---SVTLYET 163
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Match: rdgC (gene:FBgn0265959 transcript:FBtr0473730) HSP 1 Score: 162.155 bits (409), Expect = 2.908e-44 Identity = 100/252 (39.68%), Postives = 152/252 (60.32%), Query Frame = 2
Query: 110 NIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPER-----HFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVE-FYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVS------ITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKY 829
++ T++A + IQK+YRR++A+ E +R+ W+I Q +EY++EQ+Q + K + + + P+ + S +D D + DI ++A K++ PI + L++ F K N+L + + +L A L+ LPN ISPVS +T+CGD+HG DDL+ + KN LPS+SNPY+FNGDFVDRG + +EV+ +LL +L PNAVFLNRGNHED MN+RYGF +E+ +KY
Sbjct: 17 DLETTIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMPQAAGRKNQYQGSAHVSVLDD---KDDLVEEFGDI--VNA-----KIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPN---ISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKY 255
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Match: rdgC (gene:FBgn0265959 transcript:FBtr0342949) HSP 1 Score: 162.54 bits (410), Expect = 3.317e-44 Identity = 101/254 (39.76%), Postives = 152/254 (59.84%), Query Frame = 2
Query: 104 SSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPER-----HFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVE-FYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVS------ITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKY 829
+S T++A + IQK+YRR++A+ E +R+ W+I Q +EY++EQ+Q + K + + + P+ + S +D D + DI ++A K++ PI + L++ F K N+L + + +L A L+ LPN ISPVS +T+CGD+HG DDL+ + KN LPS+SNPY+FNGDFVDRG + +EV+ +LL +L PNAVFLNRGNHED MN+RYGF +E+ +KY
Sbjct: 84 ASRAEKTIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMPQAAGRKNQYQGSAHVSVLDD---KDDLVEEFGDI--VNA-----KIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPN---ISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKY 324 HSP 2 Score: 49.6766 bits (117), Expect = 3.021e-6 Identity = 18/33 (54.55%), Postives = 24/33 (72.73%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q+ +++WSDP+ GC NT RG G +FGPDVT
Sbjct: 397 QIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVT 429
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Match: rdgC (gene:FBgn0265959 transcript:FBtr0342947) HSP 1 Score: 162.54 bits (410), Expect = 3.317e-44 Identity = 101/254 (39.76%), Postives = 152/254 (59.84%), Query Frame = 2
Query: 104 SSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPER-----HFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVE-FYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVS------ITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKY 829
+S T++A + IQK+YRR++A+ E +R+ W+I Q +EY++EQ+Q + K + + + P+ + S +D D + DI ++A K++ PI + L++ F K N+L + + +L A L+ LPN ISPVS +T+CGD+HG DDL+ + KN LPS+SNPY+FNGDFVDRG + +EV+ +LL +L PNAVFLNRGNHED MN+RYGF +E+ +KY
Sbjct: 84 ASRAEKTIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMPQAAGRKNQYQGSAHVSVLDD---KDDLVEEFGDI--VNA-----KIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPN---ISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKY 324 HSP 2 Score: 49.6766 bits (117), Expect = 3.021e-6 Identity = 18/33 (54.55%), Postives = 24/33 (72.73%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q+ +++WSDP+ GC NT RG G +FGPDVT
Sbjct: 397 QIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVT 429
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Match: rdgC (gene:FBgn0265959 transcript:FBtr0342948) HSP 1 Score: 162.54 bits (410), Expect = 3.317e-44 Identity = 101/254 (39.76%), Postives = 152/254 (59.84%), Query Frame = 2
Query: 104 SSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPER-----HFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVE-FYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVS------ITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKY 829
+S T++A + IQK+YRR++A+ E +R+ W+I Q +EY++EQ+Q + K + + + P+ + S +D D + DI ++A K++ PI + L++ F K N+L + + +L A L+ LPN ISPVS +T+CGD+HG DDL+ + KN LPS+SNPY+FNGDFVDRG + +EV+ +LL +L PNAVFLNRGNHED MN+RYGF +E+ +KY
Sbjct: 84 ASRAEKTIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMPQAAGRKNQYQGSAHVSVLDD---KDDLVEEFGDI--VNA-----KIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPN---ISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKY 324 HSP 2 Score: 49.6766 bits (117), Expect = 3.021e-6 Identity = 18/33 (54.55%), Postives = 24/33 (72.73%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q+ +++WSDP+ GC NT RG G +FGPDVT
Sbjct: 397 QIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVT 429
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Match: rdgC (gene:FBgn0265959 transcript:FBtr0342946) HSP 1 Score: 160.229 bits (404), Expect = 1.217e-43 Identity = 99/248 (39.92%), Postives = 149/248 (60.08%), Query Frame = 2
Query: 122 TLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPER-----HFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVE-FYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVS------ITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKY 829
++A + IQK+YRR++A+ E +R+ W+I Q +EY++EQ+Q + K + + + P+ + S +D D + DI ++A K++ PI + L++ F K N+L + + +L A L+ LPN ISPVS +T+CGD+HG DDL+ + KN LPS+SNPY+FNGDFVDRG + +EV+ +LL +L PNAVFLNRGNHED MN+RYGF +E+ +KY
Sbjct: 5 AIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMPQAAGRKNQYQGSAHVSVLDD---KDDLVEEFGDI--VNA-----KIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPN---ISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKY 239
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Match: ppef1 (protein phosphatase, EF-hand calcium binding domain 1 [Source:ZFIN;Acc:ZDB-GENE-080303-27]) HSP 1 Score: 186.808 bits (473), Expect = 6.954e-53 Identity = 109/287 (37.98%), Postives = 159/287 (55.40%), Query Frame = 2
Query: 38 MGCKLS---SNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFD----VKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQYESD 862
MGC S N + + D I K SN T+KA +LIQ++YRRY A E +R+ W I Q +EY+ EQ+Q+ + + L N + + + + D L + + + + I + S++G +L +P++ L+ +K L + +++LL + L+ +PNV +S ITICGD+HG DDL+ IF KN LPS NPY+FNGDFVDRG KS E+I +L L P+ + LNRGNHEDH MN RYGF +E+ KYK + +LQ D
Sbjct: 1 MGCGTSIAIENQTRPSETDGSI--KQSNPALTIKAAILIQRWYRRYVAHLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFTFMLDNFTQINGNGPDLISHLLDSVVDPLTEEVRQLKYEQI-MVPESYSGPRLSFPLSVTDTNALLSAFKE-EQTLHGKYVLQLLYETKKFLKQMPNVIYLSTSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFVDRGKKSTEIIIILFAFVLLYPDHMHLNRGNHEDHIMNLRYGFTREVMQKYKTHGREILQLLQD 283 HSP 2 Score: 63.1586 bits (152), Expect = 1.840e-10 Identity = 23/33 (69.70%), Postives = 29/33 (87.88%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
QV+++LWSDP+ NGC N++RGGGCYFGPDVT
Sbjct: 435 QVVDILWSDPKHQNGCSPNSFRGGGCYFGPDVT 467
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Match: ppef1 (protein phosphatase, EF-hand calcium binding domain 1 [Source:ZFIN;Acc:ZDB-GENE-080303-27]) HSP 1 Score: 178.718 bits (452), Expect = 4.873e-50 Identity = 105/284 (36.97%), Postives = 155/284 (54.58%), Query Frame = 2
Query: 38 MGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFD----VKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQYESD 862
MGC +S +N T A +KA +LIQ++YRRY A E +R+ W I Q +EY+ EQ+Q+ + + L N + + + + D L + + + + I + S++G +L +P++ L+ +K L + +++LL + L+ +PNV +S ITICGD+HG DDL+ IF KN LPS NPY+FNGDFVDRG KS E+I +L L P+ + LNRGNHEDH MN RYGF +E+ KYK + +LQ D
Sbjct: 1 MGCG-TSIAIENQTRPSETA---------IKAAILIQRWYRRYVAHLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFTFMLDNFTQINGNGPDLISHLLDSVVDPLTEEVRQLKYEQI-MVPESYSGPRLSFPLSVTDTNALLSAFKE-EQTLHGKYVLQLLYETKKFLKQMPNVIYLSTSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFVDRGKKSTEIIIILFAFVLLYPDHMHLNRGNHEDHIMNLRYGFTREVMQKYKTHGREILQLLQD 272 HSP 2 Score: 63.1586 bits (152), Expect = 1.829e-10 Identity = 23/33 (69.70%), Postives = 29/33 (87.88%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
QV+++LWSDP+ NGC N++RGGGCYFGPDVT
Sbjct: 424 QVVDILWSDPKHQNGCSPNSFRGGGCYFGPDVT 456
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Match: ppef1 (protein phosphatase, EF-hand calcium binding domain 1 [Source:ZFIN;Acc:ZDB-GENE-080303-27]) HSP 1 Score: 178.718 bits (452), Expect = 4.873e-50 Identity = 105/284 (36.97%), Postives = 155/284 (54.58%), Query Frame = 2
Query: 38 MGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFD----VKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQYESD 862
MGC +S +N T A +KA +LIQ++YRRY A E +R+ W I Q +EY+ EQ+Q+ + + L N + + + + D L + + + + I + S++G +L +P++ L+ +K L + +++LL + L+ +PNV +S ITICGD+HG DDL+ IF KN LPS NPY+FNGDFVDRG KS E+I +L L P+ + LNRGNHEDH MN RYGF +E+ KYK + +LQ D
Sbjct: 1 MGCG-TSIAIENQTRPSETA---------IKAAILIQRWYRRYVAHLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFTFMLDNFTQINGNGPDLISHLLDSVVDPLTEEVRQLKYEQI-MVPESYSGPRLSFPLSVTDTNALLSAFKE-EQTLHGKYVLQLLYETKKFLKQMPNVIYLSTSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFVDRGKKSTEIIIILFAFVLLYPDHMHLNRGNHEDHIMNLRYGFTREVMQKYKTHGREILQLLQD 272 HSP 2 Score: 63.1586 bits (152), Expect = 1.829e-10 Identity = 23/33 (69.70%), Postives = 29/33 (87.88%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
QV+++LWSDP+ NGC N++RGGGCYFGPDVT
Sbjct: 424 QVVDILWSDPKHQNGCSPNSFRGGGCYFGPDVT 456
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Match: CU695117.1 (protein phosphatase with EF-hand domain 2a [Source:NCBI gene;Acc:100537120]) HSP 1 Score: 151.369 bits (381), Expect = 3.392e-40 Identity = 88/233 (37.77%), Postives = 135/233 (57.94%), Query Frame = 2
Query: 179 EAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHN----NPERHF-------DVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF 835
E +R+ W I Q +EY++ Q+QI + L + N + ER+ + C+ +++ ++ + +ID D ++G +L +P+ +LVE +K+ +L +R +++LLL +LR LPN+ +S ITICGD+HG +DL+ IF KN +PS PY+FNGD+VDRG S+EV+ +L L P V+LNRGNHEDH +N RYGF KE+ KYK
Sbjct: 2 EMRRRYTWNIFQSMEYADLQDQIKLYNFLGYLVDNFTPSSSERNLISHIFRENEVCRDAEW-------ERYFNYTNIDVPDI-YSGPRLTFPLDMDQAADLVEAFKN-KQQLHSRYVLQLLLETWKLLRVLPNINRVSTCHSKEITICGDLHGQLEDLLLIFYKNGMPSMEKPYVFNGDYVDRGKDSMEVLLILFAFLLVYPGDVYLNRGNHEDHIINLRYGFTKEVLGKYKL 225 HSP 2 Score: 53.9138 bits (128), Expect = 1.709e-7 Identity = 20/33 (60.61%), Postives = 26/33 (78.79%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q+L+LLWSDP +GC N RGGGCY+GP++T
Sbjct: 390 QILDLLWSDPMSQDGCVPNEVRGGGCYWGPNIT 422
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Match: ppp5c (protein phosphatase 5, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-050327-75]) HSP 1 Score: 117.087 bits (292), Expect = 6.667e-31 Identity = 74/175 (42.29%), Postives = 100/175 (57.14%), Query Frame = 2
Query: 422 ITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEIS---PVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK------FKSVLQYESDNMNECEINEWKQVLHILCF 919
+T K + +L++++K KL + ++L++ + VL LP++ EI+ ITICGD HG + DL+ IF+ N LPS +NPYLFNGDFVDRGS SVEVI L L P L RGNHE MN YGF E+ KY F V Q+ + +C IN+ V+H F
Sbjct: 176 VTLKFMEDLMDWFKD-QKKLHRKCAYQILVQVKEVLTKLPSLVEITLKESEKITICGDTHGQYYDLLNIFELNSLPSPTNPYLFNGDFVDRGSFSVEVILTLFGFKLLYPEHFHLLRGNHETDNMNQMYGFEGEVKAKYSSQMFKLFSEVFQWLP--LAQC-INDKVLVMHGGLF 346 HSP 2 Score: 36.965 bits (84), Expect = 6.667e-31 Identity = 17/30 (56.67%), Postives = 21/30 (70.00%), Query Frame = 3
Query: 954 NLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
+LLWSDP+ NG ++ RG C FGPDVT
Sbjct: 373 DLLWSDPQLQNGRSISK-RGVSCQFGPDVT 401
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Match: PPEF2 (protein phosphatase, EF-hand calcium binding domain 2 [Source:NCBI gene;Acc:100496073]) HSP 1 Score: 157.918 bits (398), Expect = 2.165e-42 Identity = 91/229 (39.74%), Postives = 132/229 (57.64%), Query Frame = 2
Query: 173 KCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITL-HNNPE--RHFDVKCK-FSKFNDILPPDKQAIPWADIDALDA--SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
+ E +R+ W I Q +EY+ EQ+QI + ++ + H P+ + D C+ F++ + D + + D + ++ S+ G L +PI LVE +K N +L +R ++ LL + L+ LPN+ IS ITICGD+HG DDL IF KN LPS PY+FNGDFVDRG +S+E++ +L L P V LNRGNHED+ +N RYGF KE+ KYK
Sbjct: 1 QMEVRRRCTWSIFQSIEYTGEQDQIKLYDFFNLLMDHFTPDNSKERDFICRIFTEEENF--KDTELEKYCDYETIEVPESYTGPHLSFPIKPTHATALVEAFKQ-NQQLHSRYVLHLLHETKKYLKQLPNIKRISTSYGKEITICGDLHGRLDDLFLIFYKNGLPSPEKPYIFNGDFVDRGKQSIEILMILFAFQLVYPKVVHLNRGNHEDYIVNLRYGFTKEVMKKYK 226 HSP 2 Score: 64.6994 bits (156), Expect = 8.673e-11 Identity = 24/33 (72.73%), Postives = 29/33 (87.88%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q++++LWSDP P +GCK NT RGGGCYFGPDVT
Sbjct: 410 QIVDILWSDPIPQDGCKSNTVRGGGCYFGPDVT 442
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Match: usp43 (ubiquitin specific peptidase 43 [Source:Xenbase;Acc:XB-GENE-940625]) HSP 1 Score: 148.288 bits (373), Expect = 4.209e-39 Identity = 84/229 (36.68%), Postives = 126/229 (55.02%), Query Frame = 2
Query: 122 TLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHF-DVKCKFSKFNDILPPDKQAIPWADIDALDA--SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMN 790
+KA +LIQ++YR Y A+ E +R+ I Q +EY+ EQ Q+ + + + HF K + + K+ + D + ++ S+ G ++ +P+T L+ +K G +L R +++L + L+ LPN+ +S ITICGD+HG DDL+ IF KN LPST N YLFNGD VDRG S+E++ +L L PN V +NRGNHED MN
Sbjct: 18 AIKAAILIQRWYRFYTARLEMRRRYTLNIFQSIEYAEEQAQLQLSNFFTFMMD-----HFAHWKGQGPDLISDISNSKEGHKFIDYEKIEVPNSYGGPRITFPLTVSDTNALLRAFKQGQ-QLHARYVLQLFHETKKFLKQLPNIVHLSTSYSKEITICGDLHGKLDDLLLIFYKNGLPSTENHYLFNGDLVDRGKNSIEILVLLFTFLLMYPNNVHINRGNHEDPIMN 240 HSP 2 Score: 59.6918 bits (143), Expect = 3.284e-9 Identity = 24/40 (60.00%), Postives = 31/40 (77.50%), Query Frame = 3
Query: 924 SFHHRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
S + QV+++LWSDPR NGC N++RGGGCYFGP+VT
Sbjct: 363 SIRKEWKQVVDILWSDPRNQNGCTPNSFRGGGCYFGPNVT 402
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Match: ppp5c (protein phosphatase 5, catalytic subunit [Source:NCBI gene;Acc:493275]) HSP 1 Score: 116.316 bits (290), Expect = 2.805e-28 Identity = 67/153 (43.79%), Postives = 88/153 (57.52%), Query Frame = 2
Query: 422 ITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEIS---PVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK------FKSVLQY 853
+T + L++FYK KL + + ++L++ + +L LP++ EIS +T+CGD HG F DL+ IF N LPS +NPY+FNGDFVDRGS SVEVI L L P L RGNHE MN YGF E+ KY F V Q+
Sbjct: 198 VTIDFMLELMQFYKD-QKKLHRKCVYQMLVQVKDILSKLPSLVEISLEKSQQVTVCGDTHGQFYDLMNIFHLNGLPSENNPYIFNGDFVDRGSFSVEVIVTLFGFKLLYPAHFHLLRGNHETDTMNQMYGFEGEVKAKYSAQMFQLFSEVFQW 349
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Match: ppp5c (protein phosphatase 5, catalytic subunit [Source:NCBI gene;Acc:493275]) HSP 1 Score: 116.316 bits (290), Expect = 2.873e-28 Identity = 64/139 (46.04%), Postives = 84/139 (60.43%), Query Frame = 2
Query: 422 ITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEIS---PVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKY 829
+T + L++FYK KL + + ++L++ + +L LP++ EIS +T+CGD HG F DL+ IF N LPS +NPY+FNGDFVDRGS SVEVI L L P L RGNHE MN YGF E+ KY
Sbjct: 198 VTIDFMLELMQFYKD-QKKLHRKCVYQMLVQVKDILSKLPSLVEISLEKSQQVTVCGDTHGQFYDLMNIFHLNGLPSENNPYIFNGDFVDRGSFSVEVIVTLFGFKLLYPAHFHLLRGNHETDTMNQMYGFEGEVKAKY 335
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Match: ppp5c (protein phosphatase 5, catalytic subunit [Source:NCBI gene;Acc:493275]) HSP 1 Score: 98.2117 bits (243), Expect = 4.748e-22 Identity = 53/103 (51.46%), Postives = 61/103 (59.22%), Query Frame = 2
Query: 563 VSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK------FKSVLQY 853
+S+ +CGD HG F DL+ IF N LPS +NPY+FNGDFVDRGS SVEVI L L P L RGNHE MN YGF E+ KY F V Q+
Sbjct: 211 LSLYMCGDTHGQFYDLMNIFHLNGLPSENNPYIFNGDFVDRGSFSVEVIVTLFGFKLLYPAHFHLLRGNHETDTMNQMYGFEGEVKAKYSAQMFQLFSEVFQW 313
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Match: Ppef2 (protein phosphatase, EF hand calcium-binding domain 2 [Source:MGI Symbol;Acc:MGI:1342304]) HSP 1 Score: 173.711 bits (439), Expect = 4.476e-48 Identity = 96/248 (38.71%), Postives = 137/248 (55.24%), Query Frame = 2
Query: 110 NIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITL-HNNPERHFDVKCKFSKFND-ILPPDKQAIPWADIDALDA--SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
N KA LIQ++YRRY A+ E +R+ W I Q +EY+ +Q+Q+ + + S + H P H + F + D + D ++++ S+ G +L +P+ LVE ++ +L R ++ LL + L LPN+ +S +T+CGD+HG DDL+ IF KN LPS Y+FNGDFVDRG SVEV+ VL L P LNRGNHEDH +N RYGF KE+ +KYK
Sbjct: 15 NAEKAFKAAALIQRWYRRYMARLEMRRRCTWNIFQSIEYAGQQDQVKLHEFFSYLVDHFTPSSHHERDFLNRMFTEERFAQDVETEEGGDFESIEVPDSYTGPRLSFPLLPDHATALVEAFRL-RQQLHARYVLNLLYETRKHLAQLPNINRVSTCYSEEVTVCGDLHGQLDDLIFIFYKNGLPSPERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKEFHLNRGNHEDHLVNLRYGFTKEVMHKYK 261 HSP 2 Score: 59.6918 bits (143), Expect = 2.613e-9 Identity = 23/33 (69.70%), Postives = 26/33 (78.79%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
QV+++LWSDP GCK N RGGGCYFGPDVT
Sbjct: 444 QVVDILWSDPAAQEGCKANAVRGGGCYFGPDVT 476
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Match: Ppef2 (protein phosphatase, EF hand calcium-binding domain 2 [Source:MGI Symbol;Acc:MGI:1342304]) HSP 1 Score: 173.711 bits (439), Expect = 4.476e-48 Identity = 96/248 (38.71%), Postives = 137/248 (55.24%), Query Frame = 2
Query: 110 NIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITL-HNNPERHFDVKCKFSKFND-ILPPDKQAIPWADIDALDA--SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
N KA LIQ++YRRY A+ E +R+ W I Q +EY+ +Q+Q+ + + S + H P H + F + D + D ++++ S+ G +L +P+ LVE ++ +L R ++ LL + L LPN+ +S +T+CGD+HG DDL+ IF KN LPS Y+FNGDFVDRG SVEV+ VL L P LNRGNHEDH +N RYGF KE+ +KYK
Sbjct: 15 NAEKAFKAAALIQRWYRRYMARLEMRRRCTWNIFQSIEYAGQQDQVKLHEFFSYLVDHFTPSSHHERDFLNRMFTEERFAQDVETEEGGDFESIEVPDSYTGPRLSFPLLPDHATALVEAFRL-RQQLHARYVLNLLYETRKHLAQLPNINRVSTCYSEEVTVCGDLHGQLDDLIFIFYKNGLPSPERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKEFHLNRGNHEDHLVNLRYGFTKEVMHKYK 261 HSP 2 Score: 59.6918 bits (143), Expect = 2.613e-9 Identity = 23/33 (69.70%), Postives = 26/33 (78.79%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
QV+++LWSDP GCK N RGGGCYFGPDVT
Sbjct: 444 QVVDILWSDPAAQEGCKANAVRGGGCYFGPDVT 476
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Match: Ppef1 (protein phosphatase with EF hand calcium-binding domain 1 [Source:MGI Symbol;Acc:MGI:1097157]) HSP 1 Score: 165.236 bits (417), Expect = 2.276e-45 Identity = 101/250 (40.40%), Postives = 148/250 (59.20%), Query Frame = 2
Query: 125 LKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIPWADIDAL---DASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQ 850
+KA L+IQ +YRRYRA+ ++ I Q +EYS+EQ Q+ + S L N + + + ++ D + Q D L S++G +L++P+T + L++ +K L ++E+L A+ VL+ +PN + ITICGD+HG DDL+ IF KN LPS +NPY+FNGDFVDRG+ S+E++ +LLVCFL P+ + LNRGNHED MN RYGF KE+ KYK + +LQ
Sbjct: 17 IKAALVIQNWYRRYRARLRVRQHYALAIFQSIEYSDEQGQMQLSSFFSFMLENYTKTNNEDSALVTRIFDNTRRESQIKDRDDFLGLIEVPDSYDGPRLQFPLTFTDIHILLQAFKQ-QQILHAHYVLEVLFEARKVLKQMPNFSHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNSMEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQ 265 HSP 2 Score: 56.225 bits (134), Expect = 3.193e-8 Identity = 23/33 (69.70%), Postives = 27/33 (81.82%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q++++LWSDPR GC NT RGGGCYFGPDVT
Sbjct: 356 QIVDILWSDPRGKKGCYPNTSRGGGCYFGPDVT 388
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Match: Ppef1 (protein phosphatase with EF hand calcium-binding domain 1 [Source:MGI Symbol;Acc:MGI:1097157]) HSP 1 Score: 146.747 bits (369), Expect = 8.155e-42 Identity = 75/158 (47.47%), Postives = 106/158 (67.09%), Query Frame = 2
Query: 392 SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQ 850
S++G +L++P+T + L++ +K L ++E+L A+ VL+ +PN + ITICGD+HG DDL+ IF KN LPS +NPY+FNGDFVDRG+ S+E++ +LLVCFL P+ + LNRGNHED MN RYGF KE+ KYK + +LQ
Sbjct: 44 SYDGPRLQFPLTFTDIHILLQAFKQ-QQILHAHYVLEVLFEARKVLKQMPNFSHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNSMEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQ 200
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Match: Ppp5c (protein phosphatase 5, catalytic subunit [Source:MGI Symbol;Acc:MGI:102666]) HSP 1 Score: 110.538 bits (275), Expect = 2.263e-26 Identity = 67/159 (42.14%), Postives = 96/159 (60.38%), Query Frame = 2
Query: 371 DIDAL--DASHNGFKLK-YPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEIS---PVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKY 829
DI+++ + ++G KL+ +T +++L+++YK KL + ++L++ + VL L + E + IT+CGD HG F DL+ IF+ N LPS +NPY+FNGDFVDRGS SVEVI L L P+ L RGNHE MN YGF E+ KY
Sbjct: 166 DIESMTIEDEYSGPKLEDGKVTITFMKDLMQWYKD-QKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKY 323
BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Match: sp|Q3SWT6|PPE1_RAT (Serine/threonine-protein phosphatase with EF-hands 1 OS=Rattus norvegicus OX=10116 GN=Ppef1 PE=2 SV=1) HSP 1 Score: 184.111 bits (466), Expect = 1.890e-51 Identity = 100/248 (40.32%), Postives = 146/248 (58.87%), Query Frame = 2
Query: 125 LKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSK-FNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQ 850
++A L+IQ +YRRYRA+ A++ I Q +EY++EQ Q+ + S L N H + S+ F + K + + + S++G +L++P+T + L++ +K L ++E+L A+ +L+ +PN I ITICGD+HG DDL+ IF KN LPS NPY+FNGDFVDRG+ S+E++ +LLV FL P + LNRGNHED MN RYGF KE+ KYK K +LQ
Sbjct: 17 VRAALIIQNWYRRYRARLSARQHYALAIFQSIEYADEQGQMQLSSFFSFMLENYTNTHKEDSALVSRLFENTRLESKDREEYVGLIDVPDSYDGPRLQFPLTFTDINLLLQAFKQ-QQTLHAHYVLEVLFEARKILKQMPNFTRIQTFPAKEITICGDLHGKLDDLMLIFYKNGLPSEKNPYVFNGDFVDRGNNSMEILMILLVSFLVYPTDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGKKILQ 263 HSP 2 Score: 57.3806 bits (137), Expect = 9.204e-8 Identity = 24/33 (72.73%), Postives = 27/33 (81.82%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q+++LLWSDPR GC NT RGGGCYFGPDVT
Sbjct: 345 QIIDLLWSDPRGKKGCYPNTSRGGGCYFGPDVT 377
BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Match: sp|O14829|PPE1_HUMAN (Serine/threonine-protein phosphatase with EF-hands 1 OS=Homo sapiens OX=9606 GN=PPEF1 PE=1 SV=1) HSP 1 Score: 182.57 bits (462), Expect = 8.350e-51 Identity = 105/252 (41.67%), Postives = 150/252 (59.52%), Query Frame = 2
Query: 119 ATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIP-WADIDALDA--SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEI--SPV-SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQ 850
+L+A L+IQ +YR Y+A+ +A++ I Q +EY++EQ Q+ + S L N H K + N L ++ W +D++D S+NG +L++P+T + L+E +K L ++E+L + VL+ +PN I SP +TICGD+HG DDL IF KN LPS NPY+FNGDFVDRG S+E++ +L V FL PN + LNRGNHED MN RYGF KE+ +KYK K +LQ
Sbjct: 15 TSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLSTFFSFMLENYTHIH---KEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKE-QQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQ 262 HSP 2 Score: 59.6918 bits (143), Expect = 1.620e-8 Identity = 25/38 (65.79%), Postives = 30/38 (78.95%), Query Frame = 3
Query: 930 HHRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
H + Q++++LWSDPR NGC NT RGGGCYFGPDVT
Sbjct: 350 EHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVT 387
BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Match: sp|O14830|PPE2_HUMAN (Serine/threonine-protein phosphatase with EF-hands 2 OS=Homo sapiens OX=9606 GN=PPEF2 PE=1 SV=2) HSP 1 Score: 174.481 bits (441), Expect = 1.761e-47 Identity = 98/248 (39.52%), Postives = 137/248 (55.24%), Query Frame = 2
Query: 110 NIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITL-HNNPERHFDVKCKFSKFN-DILPPDKQAIPWADIDALDA--SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
N KA LIQ++YRRY A+ E +R+ W I Q +EY+ +Q+Q+ + S + H P H D F D D + +D ++++ S+ G +L +P+ LVE ++ +L R ++ LL + L LPN+ +S IT+CGD+HG DDL+ IF KN LPS Y+FNGDFVDRG SVE++ +L L P LNRGNHEDH +N RYGF KE+ NKYK
Sbjct: 15 NAERAFKAAALIQRWYRRYVARLEMRRRCTWSIFQSIEYAGQQDQVKLHDFFSYLMDHFIPSSHNDRDFLTRIFTEDRFAQDSEMKKCSDYESIEVPDSYTGPRLSFPLLPDHATALVEAFRL-KQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYK 261 HSP 2 Score: 62.003 bits (149), Expect = 3.502e-9 Identity = 24/33 (72.73%), Postives = 27/33 (81.82%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
QV+++LWSDP GCK NT RGGGCYFGPDVT
Sbjct: 440 QVVDILWSDPMAQEGCKANTIRGGGCYFGPDVT 472
BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Match: sp|G5EBX9|PPE_CAEEL (Serine/threonine-protein phosphatase with EF-hands pef-1 OS=Caenorhabditis elegans OX=6239 GN=pef-1 PE=1 SV=1) HSP 1 Score: 173.326 bits (438), Expect = 2.753e-47 Identity = 92/258 (35.66%), Postives = 144/258 (55.81%), Query Frame = 2
Query: 122 TLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIPWADIDA------------------LDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
T+K+ +LIQK+YRR A+ EA+R+ W+I +EY+ EQ+Q+ + + + E + + + + ++ + +D+ +D ++ G L P+ V ++E +K N L + ++ +L A+ + + +P+V IS +TICGD+HG FDDL I KN PS NPY+FNGDFVDRG +S+EV+ VL + +P +++LNRGNHEDH MN RYGF KEL+ KYK
Sbjct: 82 TIKSAILIQKWYRRCEARLEARRRATWQIFTALEYAGEQDQLKLYDFFADVIRAMAEENGKGGVENGRNSPLMSALSHYAKPSLMDSEGETVKKMLEDTSPTNVDIDRNYKGPTLSLPLDKPQVAKMIEAFKV-NKVLHPKYVLMILHEARKIFKAMPSVSRISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIVDPMSIYLNRGNHEDHIMNLRYGFIKELSTKYK 338
BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Match: sp|O35385|PPE2_MOUSE (Serine/threonine-protein phosphatase with EF-hands 2 OS=Mus musculus OX=10090 GN=Ppef2 PE=2 SV=1) HSP 1 Score: 173.711 bits (439), Expect = 3.131e-47 Identity = 96/248 (38.71%), Postives = 137/248 (55.24%), Query Frame = 2
Query: 110 NIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITL-HNNPERHFDVKCKFSKFND-ILPPDKQAIPWADIDALDA--SHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
N KA LIQ++YRRY A+ E +R+ W I Q +EY+ +Q+Q+ + + S + H P H + F + D + D ++++ S+ G +L +P+ LVE ++ +L R ++ LL + L LPN+ +S +T+CGD+HG DDL+ IF KN LPS Y+FNGDFVDRG SVEV+ VL L P LNRGNHEDH +N RYGF KE+ +KYK
Sbjct: 15 NAEKAFKAAALIQRWYRRYMARLEMRRRCTWNIFQSIEYAGQQDQVKLHEFFSYLVDHFTPSSHHERDFLNRMFTEERFAQDVETEEGGDFESIEVPDSYTGPRLSFPLLPDHATALVEAFRL-RQQLHARYVLNLLYETRKHLAQLPNINRVSTCYSEEVTVCGDLHGQLDDLIFIFYKNGLPSPERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKEFHLNRGNHEDHLVNLRYGFTKEVMHKYK 261 HSP 2 Score: 59.6918 bits (143), Expect = 1.828e-8 Identity = 23/33 (69.70%), Postives = 26/33 (78.79%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
QV+++LWSDP GCK N RGGGCYFGPDVT
Sbjct: 444 QVVDILWSDPAAQEGCKANAVRGGGCYFGPDVT 476
BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Match: A0A210Q9C4 (Serine/threonine-protein phosphatase with EF-hands OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT12726 PE=3 SV=1) HSP 1 Score: 187.963 bits (476), Expect = 1.915e-55 Identity = 117/355 (32.96%), Postives = 172/355 (48.45%), Query Frame = 2
Query: 92 IACKSSNIVA----------TLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHN-NPERHFDVKCKFSKFNDILPP---DKQAIPWADIDAL----------DASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEIS---PVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKY--------------------------------------------------KFKSVLQ----YESDNMNECEINEWKQVLHIL 913
+ C S+ VA +++ +LIQK+YRRY A+ E +R+ W I Q +EYS EQNQ+ + + L P+R K + ++ P D + + D L + +NG L +P+ +++L++ +K+ L + L++LL + +L+ N+ + IT+CGD+HG DDL +F KN LPS NPY+FNGDFVDRG+ SVE+ +L CFL NPN V++NRGNHEDH MN RYGF KE+N KY KF S L ++ +N+ E E+ EWKQVL +L
Sbjct: 1 MGCTSAKTVAPEESSTKSEKVIRSAILIQKWYRRYMARLEMRRRCTWNIFQSIEYSGEQNQLKLYNFFADMLKQMKPDRTGQPKILRALSDNNRRPINCDVRTLEAEDAGLLLLSNPNDIEVGSHYNGMHLTFPLNQSQLQDLIQSFKT-KKLLHAKYLLQLLHETRTLLKQKSNINRATISISKQITVCGDLHGKLDDLYMVFHKNGLPSVDNPYIFNGDFVDRGTNSVEISVILFACFLLNPNEVYINRGNHEDHIMNIRYGFVKEVNKKYSVYANGILRLFEDLFSWLPLATIIDDKVLVVHGGLSDTIDLDLISQLDRHKFLSTLHPSRSFDDENVTEVELMEWKQVLDLL 354 HSP 2 Score: 58.151 bits (139), Expect = 1.915e-55 Identity = 25/33 (75.76%), Postives = 28/33 (84.85%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
QVL+LLWSDPR +GC NT+RGGG YFGPDVT
Sbjct: 349 QVLDLLWSDPRVQDGCLPNTFRGGGSYFGPDVT 381
BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Match: K7GM53 (Serine/threonine-protein phosphatase OS=Sus scrofa OX=9823 GN=PPEF1 PE=3 SV=2) HSP 1 Score: 185.652 bits (470), Expect = 7.342e-55 Identity = 110/274 (40.15%), Postives = 154/274 (56.20%), Query Frame = 2
Query: 38 MGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHF-DVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVY--EISPV-SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVL 847
MGC SS + K LKA L+IQ +YR Y A+ +A+++ I Q +EY++EQ Q+ + S L N H D + F+ + K + + + S++G +L++P+T + L+E +K L ++E+L + VL+ +PN + SP ITICGD+HG DDL IF KN LPS SNPY+FNGDFVDRG S+E++ +L V FL PN + LNRGNHED MN RYGF KE+ +KYK KSVL
Sbjct: 1 MGCGTSS------------SAKDRKSENALKAALVIQNWYRGYSARLKARQRYALTIFQSIEYADEQGQLQLSNFFSFMLENYTHVHEKDRELVTRLFSGSIQDKKDRQDYLGLIDVPDSYSGPRLQFPLTFTDIDLLIEAFKQ-QQILHAYYVLEVLFETKKVLQQMPNFTHTKTSPSKEITICGDLHGKLDDLFLIFYKNGLPSVSNPYVFNGDFVDRGKNSMEILMILFVSFLVYPNDLHLNRGNHEDFMMNMRYGFTKEILHKYKMKSVL 261 HSP 2 Score: 58.5362 bits (140), Expect = 7.342e-55 Identity = 24/37 (64.86%), Postives = 29/37 (78.38%), Query Frame = 3
Query: 933 HRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
H + QV+++LWSDPR GC NT RGGGCYFGPD+T
Sbjct: 301 HEWEQVVDILWSDPRGKRGCYPNTSRGGGCYFGPDIT 337
BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Match: A0A1A7WZV7 (Serine/threonine-protein phosphatase OS=Iconisemion striatum OX=60296 GN=PPEF1 PE=3 SV=1) HSP 1 Score: 189.504 bits (480), Expect = 7.924e-54 Identity = 109/283 (38.52%), Postives = 153/283 (54.06%), Query Frame = 2
Query: 38 MGCKLS---SNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPP------DKQAIPWAD------IDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
MGC S K D+ A KS + T+KA +LIQ++YRRY A+ E +R+ W I Q +EY+ EQ Q+ + + L N F++ N P D PW D + ++ S+ G ++ +P+T L+ +K L + +++LL + +L+ +PN+ +S ITICGD+HG DDL+ IF KN LPS PY+FNGDFVDRG KSVEV+ +L L P+ + LNRGNHEDH MN RYGF KE+ KYK
Sbjct: 1 MGCGTSVATETQVKRLETDE--AVKSPSPALTMKAAVLIQRWYRRYMARLEMRRRYTWNIFQSIEYAGEQEQLQLSSFFTYMLDN-----------FTQLNGNGPDLISQLLDPVVDPWMDRETCYKLISVPESYTGPRISFPLTISDTTALLSAFKE-QQILHAKYVLQLLNETKKLLKQMPNIVHLSTSYTKEITICGDLHGRLDDLLLIFYKNGLPSAETPYVFNGDFVDRGKKSVEVVILLFAYLLLYPDHMHLNRGNHEDHIMNLRYGFTKEVMQKYK 269
BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Match: V4AJL5 (Serine/threonine-protein phosphatase (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_104853 PE=3 SV=1) HSP 1 Score: 197.978 bits (502), Expect = 1.145e-53 Identity = 106/244 (43.44%), Postives = 151/244 (61.89%), Query Frame = 2
Query: 131 AVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSK-FNDILPPDKQAIPWADIDA------LDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNV-YEISPVS--ITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
A +LIQK+YR Y A+ EA+R+ W I Q +EYS EQ+Q+ + + ++ N + D + K ++ F P A +DI +++S+ G L +PIT V+ L++ +K+ +L R L+ELL Q + + + N+ Y + +S IT+CGD+HG +DL IF KN LPS NP++FNGDFVDRG+ S+EV +L CFL +PN VFLNRGNHEDH MN RYGF KE+ KYK
Sbjct: 1 AAILIQKWYRMYVARLEARRRYTWTIFQSIEYSGEQDQLKLHNFFN-SMINQLKLDTDGQPKIARAFASSQRPAVVASETSDISGCIEGIEVESSYTGPHLTFPITHAQVKTLIQAFKA-KRRLHVRYLLELLNETQKLFKQMKNINYASTSISKQITVCGDLHGKLEDLYMIFHKNGLPSVDNPFVFNGDFVDRGASSIEVSIILFACFLASPNEVFLNRGNHEDHVMNMRYGFMKEIIRKYK 242 HSP 2 Score: 68.5514 bits (166), Expect = 7.849e-9 Identity = 26/35 (74.29%), Postives = 30/35 (85.71%), Query Frame = 3
Query: 939 YFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Y QVL+LLWSDP+ L GC NT+RGGGCYFGPD+T
Sbjct: 383 YVQVLDLLWSDPKSLMGCNPNTFRGGGCYFGPDIT 417
BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Match: A0A5F4VSH6 (Serine/threonine-protein phosphatase OS=Callithrix jacchus OX=9483 GN=PPEF1 PE=3 SV=1) HSP 1 Score: 195.667 bits (496), Expect = 1.437e-53 Identity = 117/274 (42.70%), Postives = 162/274 (59.12%), Query Frame = 2
Query: 38 MGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPE-RHFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEI--SPV-SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVL 847
MGC SS KN+ +L+AVL+IQ +YR YRA+ +A+R I +EY++EQ+QI + S L N R ++ + + DKQ + D+D D S+ G +L++P+T + L+E +K G L ++E+L +L+ +PN ++ SP IT+CGD+HGN DDL IF KN LPS SNPY+FNGDFVDRG S+EV+ +L V FL PN + LNRGNHED+ MN RYGF KE+ +KYK KSVL
Sbjct: 1 MGCNTSSTRIKNSQ-------------ISLRAVLIIQNWYRGYRARLKARRHFALTIFHSLEYADEQDQIQLCNFFSFMLENYTHIRKEEIGLNQLADSKLDMRDKQ--DYVDLDVPD-SYQGPRLQFPLTCADIDLLLEAFK-GKQILHAHYVLEVLFETMKLLKQMPNFTQVQTSPSKEITVCGDLHGNLDDLFLIFYKNGLPSGSNPYVFNGDFVDRGRNSIEVLMILCVSFLVYPNDLHLNRGNHEDYMMNLRYGFTKEILHKYKMKSVL 257
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Match: ppef1 (serine/threonine-protein phosphatase with EF-hands 1 [Source:NCBI gene;Acc:103021363]) HSP 1 Score: 185.267 bits (469), Expect = 1.999e-52 Identity = 106/284 (37.32%), Postives = 159/284 (55.99%), Query Frame = 2
Query: 38 MGCKLSSNLFKNNTNDDM-IACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFND-ILPPDKQAIPWADID--ALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQYESD 862
MGC S + ++ ++ + + T+KA +LIQ++YRRY A+ E +R+ W I Q +EY+ EQ+Q+ + S L N + + + S D + P + + + + S++G +L +P++ L+ +K L + +++LL Q L+ +PNV +S ITICGD+HG DDL+ IF KN LPS NPY+FNGDFVDRG KS+E+I +L L P+ + LNRGNHEDH MN RYGF KE+ KYK + +LQ D
Sbjct: 1 MGCGTSVAIENQGRPSEVDVSARLPSPALTMKAAILIQRWYRRYVARLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFSFMLDNFTQLNGNGPDLISHLLDSAVDPVVDEVRQSKYEQIVVPESYSGPRLSFPLSVTDTNVLLSAFKE-QQTLHAKYVLQLLHETQKFLKQMPNVIYLSSSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFVDRGKKSIEIIIILFAFLLLYPDHMHLNRGNHEDHIMNLRYGFTKEVMQKYKTHGREILQLLQD 283 HSP 2 Score: 62.003 bits (149), Expect = 3.455e-10 Identity = 22/33 (66.67%), Postives = 29/33 (87.88%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q++++LWSDP+ NGC N++RGGGCYFGPDVT
Sbjct: 434 QIVDVLWSDPKIQNGCSPNSFRGGGCYFGPDVT 466
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Match: ppef1 (serine/threonine-protein phosphatase with EF-hands 1 [Source:NCBI gene;Acc:103021363]) HSP 1 Score: 180.259 bits (456), Expect = 1.188e-50 Identity = 107/283 (37.81%), Postives = 156/283 (55.12%), Query Frame = 2
Query: 38 MGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFND-ILPPDKQAIPWADID--ALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQYESD 862
MGC S + +N +A +KA +LIQ++YRRY A+ E +R+ W I Q +EY+ EQ+Q+ + S L N + + + S D + P + + + + S++G +L +P++ L+ +K L + +++LL Q L+ +PNV +S ITICGD+HG DDL+ IF KN LPS NPY+FNGDFVDRG KS+E+I +L L P+ + LNRGNHEDH MN RYGF KE+ KYK + +LQ D
Sbjct: 1 MGCGTSVAI-ENQGRPSEVA---------MKAAILIQRWYRRYVARLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFSFMLDNFTQLNGNGPDLISHLLDSAVDPVVDEVRQSKYEQIVVPESYSGPRLSFPLSVTDTNVLLSAFKE-QQTLHAKYVLQLLHETQKFLKQMPNVIYLSSSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFVDRGKKSIEIIIILFAFLLLYPDHMHLNRGNHEDHIMNLRYGFTKEVMQKYKTHGREILQLLQD 272 HSP 2 Score: 62.003 bits (149), Expect = 3.435e-10 Identity = 22/33 (66.67%), Postives = 29/33 (87.88%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q++++LWSDP+ NGC N++RGGGCYFGPDVT
Sbjct: 423 QIVDVLWSDPKIQNGCSPNSFRGGGCYFGPDVT 455
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Match: ENSAMXT00000016118.2 (pep primary_assembly:Astyanax_mexicanus-2.0:14:38271079:38284894:-1 gene:ENSAMXG00000015666.2 transcript:ENSAMXT00000016118.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 177.563 bits (449), Expect = 1.063e-49 Identity = 100/245 (40.82%), Postives = 145/245 (59.18%), Query Frame = 2
Query: 125 LKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITL-HNNP---ERHFDVKCKFSKFNDILPPDKQAIPWADIDALDAS--HNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
++A LLIQ++YR+Y A+ E +R+ W I Q +EYS EQ+QI + + H P ER ++ + +++ D + P+ ++D + G L +P+T I+ LVE +K L R +++LL +LR LPN+ E+S ITICGD+HG +DL+ +F KN LPS PY+FNGDFVDRG S+E++ +L L PN V LNRGNHEDH +N RYGF KE+ KY+
Sbjct: 1 MRAALLIQRWYRQYVARLEMRRRCTWNIFQSIEYSGEQDQIKLYNFFGFLMDHFTPASSER--NLISHIFRESEVFQ-DAEWEPYFCYKSIDVPDMYTGPHLTFPLTVNIITELVEAFKH-KQHLHARYVLQLLGETWRLLRILPNINEVSTFHSKEITICGDLHGQLEDLLLVFYKNGLPSVETPYVFNGDFVDRGKDSIEILLILFAFQLVYPNDVHLNRGNHEDHIVNLRYGFTKEVLGKYR 241 HSP 2 Score: 53.1434 bits (126), Expect = 2.603e-7 Identity = 19/33 (57.58%), Postives = 26/33 (78.79%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q++++LWSDP +GC N RGGGCY+GPD+T
Sbjct: 406 QIVDMLWSDPMSQDGCIPNEVRGGGCYWGPDIT 438
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Match: PPEF2 (protein phosphatase with EF-hand domain 2 [Source:HGNC Symbol;Acc:HGNC:9244]) HSP 1 Score: 166.777 bits (421), Expect = 1.347e-45 Identity = 103/283 (36.40%), Postives = 159/283 (56.18%), Query Frame = 2
Query: 38 MGCKLS-SNLFKNNTNDD--MIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHN----NPERHF-------DVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF 835
MGC ++ F + D +I+ + S + ++A +LIQ++YR+Y A+ E +R+ W I Q +EY+ +Q+QI + L + N + ER+ + C+ ++ D + I DI ++G +L +P+ + +LVE ++S +L +R +++LL +LR LPN+ IS ITICGD+HG +DL+ IF KN +PS Y+FNGDFVDRG S+E++ +L L P V LNRGNHEDH +N RYGF KE+ KYK
Sbjct: 1 MGCGVTKGGEFHKRYDKDGNIISVRISAVTKAIRAAVLIQRWYRQYVARMELRRRYTWNIFQSIEYAGQQDQIKLYNFLGYLVDNFTPSSNERNLISHIFRENEVCRDIEWERFF--DYRHIEVPDI------YSGPRLTFPLNADQAADLVEAFRS-KQQLHSRYVLQLLGETWKLLRVLPNINRISTCHSKEITICGDLHGQLEDLLLIFYKNGMPSMEKAYVFNGDFVDRGKDSIEILLILFAFLLVYPGEVHLNRGNHEDHIINLRYGFTKEVLGKYKM 274 HSP 2 Score: 53.1434 bits (126), Expect = 1.655e-7 Identity = 21/33 (63.64%), Postives = 26/33 (78.79%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q+L+LLWSDP +GC N RGGGCY+GP+VT
Sbjct: 444 QILDLLWSDPMIPDGCVPNEVRGGGCYWGPNVT 476 HSP 3 Score: 21.1718 bits (43), Expect = 1.655e-7 Identity = 7/10 (70.00%), Postives = 9/10 (90.00%), Query Frame = 2
Query: 884 NEWKQVLHIL 913
NEWKQ+L +L
Sbjct: 440 NEWKQILDLL 449
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Match: ppp5c (protein phosphatase 5 catalytic subunit [Source:NCBI gene;Acc:103034548]) HSP 1 Score: 115.931 bits (289), Expect = 2.010e-28 Identity = 63/139 (45.32%), Postives = 87/139 (62.59%), Query Frame = 2
Query: 422 ITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEIS---PVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKY 829
+T K ++ +++++K KL + ++L++ + VL LP++ EI+ ITICGD HG + DL+ IF+ N LPS +NPYLFNGDFVDRGS S+EVI L L P+ L RGNHE MN YGF E+ KY
Sbjct: 179 VTLKFMKEMMDWFKD-QKKLHRKCAYQMLVQVKEVLSKLPSLVEITLKETEKITICGDTHGQYYDLLNIFELNGLPSPTNPYLFNGDFVDRGSFSMEVILTLFGFKLLYPDHFHLLRGNHETDNMNQMYGFEGEVKAKY 316
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Sea Lamprey
Match: ppp5c (protein phosphatase 5, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-050327-75]) HSP 1 Score: 116.701 bits (291), Expect = 1.374e-29 Identity = 67/155 (43.23%), Postives = 92/155 (59.35%), Query Frame = 2
Query: 422 ITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVS-----ITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK------FKSVLQY 853
+T ++ L+E++K KL + ++LL+ + L+ LP++ E++ IT+CGDIHG + DL+ IF+ N LPS +NPY+FNGDFVDRGS SVEVI VL L P+ L RGNHE MN YGF E+ KY F V Q+
Sbjct: 146 VTITFMKELIEWFKD-QKKLHRKYAYQILLQVKQSLQKLPSLVEVTIKDEQGDMITVCGDIHGQYFDLLHIFELNGLPSETNPYVFNGDFVDRGSWSVEVILVLFGFKLLYPDHFHLMRGNHETDNMNQMYGFEGEVKAKYTAQMFDFFSEVFQW 299
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Sea Lamprey
Match: ppp1cb (protein phosphatase 1, catalytic subunit, beta isozyme [Source:ZFIN;Acc:ZDB-GENE-030616-609]) HSP 1 Score: 85.8853 bits (211), Expect = 6.916e-20 Identity = 44/120 (36.67%), Postives = 70/120 (58.33%), Query Frame = 2
Query: 479 LSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFK 838
++ ++ L ++++ + P + E+ + ICGDIHG + DL+ +F+ P SN YLF GD+VDRG +S+E I +LL ++ P FL RGNHE +N YGF+ E ++ K
Sbjct: 16 MTEAEVRGLCIKSREIFLSQPILLELE-APLKICGDIHGQYTDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIK 133
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Sea Lamprey
Match: ppp1cab (protein phosphatase 1, catalytic subunit, alpha isozyme b [Source:ZFIN;Acc:ZDB-GENE-030131-5512]) HSP 1 Score: 87.4261 bits (215), Expect = 7.571e-20 Identity = 48/123 (39.02%), Postives = 72/123 (58.54%), Query Frame = 2
Query: 470 NNKLSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFK 838
N +L+ ++ L L+++ + P + E+ + ICGDIHG + DL+ +F+ P SN YLF GD+VDRG +S+E I +LL ++ P FL RGNHE +N YGF+ E +Y K
Sbjct: 9 NVQLTEGEIRGLCLKSREIFLSQPILLELE-APLKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHEAS-INRIYGFYDECKRRYNIK 128
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005085.1 (pep scaffold:Pmarinus_7.0:GL481040:2845:3652:-1 gene:ENSPMAG00000004627.1 transcript:ENSPMAT00000005085.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 82.8037 bits (203), Expect = 1.071e-19 Identity = 43/110 (39.09%), Postives = 66/110 (60.00%), Query Frame = 2
Query: 479 LSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFF 808
+S ++ L ++++ + P + E+ + ICGDIHG + DL+ +F+ P SN YLF GD+VDRG +S+E I +LL ++ P FL RGNHE +N YGF+
Sbjct: 26 MSEAEVRALCIKSREIFLSQPILLELE-APLKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFY 133
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005238.1 (pep scaffold:Pmarinus_7.0:GL487052:8065:11513:-1 gene:ENSPMAG00000004764.1 transcript:ENSPMAT00000005238.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 80.4925 bits (197), Expect = 1.623e-18 Identity = 45/119 (37.82%), Postives = 68/119 (57.14%), Query Frame = 2
Query: 506 LLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQYESD 862
L +A+ +L NV E+ +T+CGD+HG F DL+ +F +N YLF GD+VDRG SVE +S+L+ ++ + + RGNHE + YGF+ E KY +V +Y +D
Sbjct: 12 LSQAKEILTKESNVQEVR-CPVTVCGDVHGQFHDLIELFNIGGKSPDTN-YLFMGDYVDRGYYSVETVSLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTD 128
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Match: PPT1 (Protein serine/threonine phosphatase; regulates Hsp90 chaperone by affecting its ATPase and cochaperone binding activities; has similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth [Source:SGD;Acc:S000003355]) HSP 1 Score: 89.3521 bits (220), Expect = 3.984e-20 Identity = 50/122 (40.98%), Postives = 69/122 (56.56%), Query Frame = 2
Query: 479 LSNRDLIELLLRAQVVLRDLPNVYEI----SP-VSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKY 829
L + + ++ A + R P++ E+ +P V I++CGD HG F D++ +F+K + YLFNGDFVDRGS S EV + + +PN FLNRGNHE MN YGF E KY
Sbjct: 209 LPKKYVAAIISHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTYLFNGDFVDRGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKY 330
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Match: GLC7 (Type 1 S/T protein phosphatase (PP1) catalytic subunit; involved in glycogen metabolism, sporulation and mitotic progression; interacts with multiple regulatory subunits; regulates actomyosin ring formation; subunit of CPF; recruited to mating projections by Afr1p interaction; regulates nucleocytoplasmic shuttling of Hxk2p; import into the nucleus is inhibited during spindle assembly checkpoint arrest; involved in dephosphorylating Rps6a/b and Bnr1p [Source:SGD;Acc:S000000935]) HSP 1 Score: 85.8853 bits (211), Expect = 1.513e-19 Identity = 51/138 (36.96%), Postives = 75/138 (54.35%), Query Frame = 2
Query: 434 IVRNLVEFYKSGNNK---LSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFK 838
I+ L+E S + L ++ L +A+ + P + E+ I ICGDIHG + DL+ +F+ P SN YLF GD+VDRG +S+E I +LL ++ P F+ RGNHE +N YGF+ E +Y K
Sbjct: 11 IIDRLLEVRGSKPGQQVDLEENEIRYLCSKARSIFIKQPILLELE-APIKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIK 146
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Match: PPZ1 (Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance [Source:SGD;Acc:S000004478]) HSP 1 Score: 87.8113 bits (216), Expect = 1.590e-19 Identity = 46/113 (40.71%), Postives = 73/113 (64.60%), Query Frame = 2
Query: 479 LSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCF-LQNPNAVFLNRGNHEDHFMNSRYGFFKE 814
L N +++++ ++A+ + P++ E+SP + I GD+HG + DL+ +F K P +SN YLF GD+VDRG +S+E I +LL C+ ++ P FL RGNHE + YGF+ E
Sbjct: 385 LKNNEILQICIKAREIFLSQPSLLELSP-PVKIVGDVHGQYGDLLRLFTKCGFPPSSN-YLFLGDYVDRGKQSLETI-LLLFCYKIKYPENFFLLRGNHECANVTRVYGFYDE 494
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Match: PPH21 (Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; forms nuclear foci upon DNA replication stress; PPH21 has a paralog, PPH22, that arose from the whole genome duplication [Source:SGD;Acc:S000002292]) HSP 1 Score: 85.1149 bits (209), Expect = 5.679e-19 Identity = 51/128 (39.84%), Postives = 72/128 (56.25%), Query Frame = 2
Query: 479 LSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQYESD 862
LS D+ L A VL+ NV I+ V +TICGD+HG F DL+ +F+ P YLF GD+VDRG SVE +S L+ ++ P+ + + RGNHE + YGF+ E KY +V + +D
Sbjct: 83 LSEDDVARLCKMAVDVLQFEENVKPIN-VPVTICGDVHGQFHDLLELFKIGG-PCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTD 208
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Match: PPH22 (Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; protein abundance increases in response to DNA replication stress; dephosphorylates Tel1p/Mec1p-phosphorylated Cdc13p to promote telomerase release from telomeres at G2/M; PPH22 has a paralog, PPH21, that arose from the whole genome duplication [Source:SGD;Acc:S000002347]) HSP 1 Score: 84.7297 bits (208), Expect = 8.199e-19 Identity = 52/128 (40.62%), Postives = 72/128 (56.25%), Query Frame = 2
Query: 479 LSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQYESD 862
LS D+ L A VL+ NV I+ V +TICGD+HG F DL+ +F K P YLF GD+VDRG SVE +S L+ ++ P+ + + RGNHE + YGF+ E KY +V + +D
Sbjct: 91 LSEDDVARLCKMAVDVLQFEENVKPIN-VPVTICGDVHGQFHDLLELF-KIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTD 216
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Match: EDO47034 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7RNB7]) HSP 1 Score: 185.267 bits (469), Expect = 3.647e-53 Identity = 112/286 (39.16%), Postives = 159/286 (55.59%), Query Frame = 2
Query: 38 MGCKLSSNLFK--NNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQI-LMQKLLSITLHNNPERHFDVKCKFSKFNDILPPD--------------KQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLR-AQVVLRDLPNVYEIS---PVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
MGC S + +K + + + KS L++ +LIQ ++RRYRA+ EA+R+ WKI Q +EYS EQ+Q+ L + H P+ + D L + + A +DI ++ ++ G +K PIT VRN++E K NKL + + L+LR A+ R LPNV ++ +TICGD+HG DDL IF KN LPS NPY+FNGD VDRG +S+E+ +L + PN V++NRGNHEDH MN RYGF KE+ +KYK
Sbjct: 1 MGCGTSVDAYKEYDGHKNSLSLSKSEK---ALRSAVLIQNWFRRYRARLEARRRCTWKIFQSIEYSGEQDQLKLFNFFTDMLTHVQPDNTGASRANI--IEDTLSRNGSASSTSSKSSTTLEAATDPSDI-KVEPTYTGHVVKLPITLMSVRNIIEQCKL--NKLVHAKYVLLILREARERFRALPNVIRVTTRIAKQMTICGDLHGKLDDLFMIFHKNGLPSPENPYIFNGDLVDRGPRSIEICIILFAFTILYPNGVYINRGNHEDHIMNLRYGFVKEVMDKYK 278 HSP 2 Score: 65.4698 bits (158), Expect = 9.986e-12 Identity = 29/42 (69.05%), Postives = 33/42 (78.57%), Query Frame = 3
Query: 918 SCSFHHRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
S S + QVL+LLWSDP+P GCK NT+RGGGCYFGPDVT
Sbjct: 344 SLSSLKEWRQVLDLLWSDPKPTPGCKPNTFRGGGCYFGPDVT 385
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Match: EDO44648 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7RVJ0]) HSP 1 Score: 90.8929 bits (224), Expect = 8.951e-21 Identity = 53/138 (38.41%), Postives = 79/138 (57.25%), Query Frame = 2
Query: 434 IVRNLVEFYKS--GNN-KLSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFK 838
I+ L+E S G N +L+ ++ L L+++ + P + E+ + ICGDIHG + DL+ +F+ P SN YLF GD+VDRG +S+E I +LL ++ P FL RGNHE +N YGF+ E +Y K
Sbjct: 12 IISRLLEVRGSRPGKNVQLTEAEIRGLCLKSREIFLSQPILLELE-APLKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIK 147
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Match: EDO29759 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7T2Q5]) HSP 1 Score: 87.0409 bits (214), Expect = 1.568e-19 Identity = 47/129 (36.43%), Postives = 75/129 (58.14%), Query Frame = 2
Query: 476 KLSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQYESD 862
+L+ + L +A+ +L NV E+ +T+CGD+HG F DL+ +F+ +N YLF GD+VDRG SVE +++L+ ++ P+ + + RGNHE + YGF+ E KY SV +Y +D
Sbjct: 23 QLTEAQVKTLCEKAKEILSKESNVQEVK-CPVTVCGDVHGQFHDLMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVTLKVRFPHRICILRGNHESRQITQVYGFYDECLRKYGNASVWKYFTD 149
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Match: EDO49936 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7RFC7]) HSP 1 Score: 84.7297 bits (208), Expect = 1.046e-18 Identity = 51/127 (40.16%), Postives = 76/127 (59.84%), Query Frame = 2
Query: 479 LSNRDLIELLLRAQVVLRDLPNVYEI-SPVSITICGDIHGNFDDLVTIFQKNC-LPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQY 853
++ +++ +L +A+ +L + NV + SPV T+CGDIHG F DL +F+ +P T+ YLF GDFVDRG SVE +LL ++ P+ + L RGNHE + YGF+ E KY +V +Y
Sbjct: 20 ITEKEVKQLCAKAREILVEESNVQRVDSPV--TVCGDIHGQFYDLKELFKVGGDVPDTN--YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLKKYGSITVWRY 142
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Match: EDO38434 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7SD13]) HSP 1 Score: 80.4925 bits (197), Expect = 4.113e-18 Identity = 44/103 (42.72%), Postives = 62/103 (60.19%), Query Frame = 2
Query: 554 ISPVS--ITICGDIHGNFDDLVTIFQKNC-LPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQY 853
+ PVS +T+CGDIHG F DL +F+ +P+TS Y+F GDFVDRG S+E + LL + P+ + L RGNHE + YGF+ E +KY + +Y
Sbjct: 39 VQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTS--YVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSKYGNANAWRY 139
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Match: PPEF2 (serine/threonine-protein phosphatase with EF-hands 2 [Source:NCBI gene;Acc:101170112]) HSP 1 Score: 167.933 bits (424), Expect = 2.783e-46 Identity = 106/279 (37.99%), Postives = 158/279 (56.63%), Query Frame = 2
Query: 38 MGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITL-HNNP---ER-------HFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEIS---PVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
MGC + K++ + + S V ++A LLIQ++YR+Y A+ E +R+ W I Q +EY+ EQ+QI + + H P ER H + C+ +++ ++ + DI+ D S+ G L +P+T V LVE +K +L R ++++L +LR LPN+ +S ITICGD+HG +DL+ IF KN LPS+ PY+FNGDFVDRG S+E++ +L L PN + LNRGNHEDH +N RYGF KE+ KY+
Sbjct: 1 MGCGMG----KSSLQEKKCSRVSIYSVPAIRAALLIQRWYRQYVARLEMRRRCTWNIFQSIEYAGEQDQIKLYSFFGFLMDHFTPASSERNLISHIFHENEICRDTEW-------ERYFCYKDIEVPD-SYTGPHLTFPMTFCGVSKLVEAFKH-KQQLHARYVLQILGETWRLLRILPNINYVSVSQTKEITICGDLHGQLEDLLLIFYKNGLPSSEKPYIFNGDFVDRGKSSLEILLILFGFLLVYPNDLHLNRGNHEDHIVNLRYGFTKEILGKYR 266 HSP 2 Score: 63.5438 bits (153), Expect = 1.146e-10 Identity = 25/37 (67.57%), Postives = 29/37 (78.38%), Query Frame = 3
Query: 933 HRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
H + Q++NLLWSDP P NGC N RGGGCY+GPDVT
Sbjct: 423 HDWKQIVNLLWSDPMPQNGCISNEVRGGGCYWGPDVT 459
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Match: ppef1 (protein phosphatase with EF-hand domain 1 [Source:NCBI gene;Acc:101174574]) HSP 1 Score: 166.007 bits (419), Expect = 1.636e-45 Identity = 112/296 (37.84%), Postives = 163/296 (55.07%), Query Frame = 2
Query: 38 MGCKLS----SNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPP------DKQAIPWADID------ALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKF--KSVLQYESD 862
MGC S + L K T++ A ++ ++ T+KA +LIQ++YRRY A+ E +R+ W I Q +EY+ EQ+Q+ + S L N F++ + P D PW D + + S+ G ++ +P+ L+ +K L R +++LL A+ +L+ +PN+ +S ITICGD+HG+ DDL+ IF KN LPS PY+FNGDFVDRG KSVEV+ +L FL P+ + LNRGNHED MN RYGF KE+ KYK + +LQ D
Sbjct: 1 MGCGTSVATETQLKKLETDE---AGRTPSLALTIKAAVLIQRWYRRYMARLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFSFMLDN-----------FTQLSGNGPDLITQLLDPVVDPWLDREICYNLVPVPDSYTGPRISFPLGVSDTNTLLSAFKE-QQILHARYVLQLLYEAKKLLKQMPNINHLSTSYTKDITICGDLHGHLDDLLLIFYKNGLPSAETPYVFNGDFVDRGKKSVEVVIMLFAYFLLYPDYMHLNRGNHEDPIMNLRYGFTKEVMQKYKIHGREILQLFQD 281 HSP 2 Score: 58.9214 bits (141), Expect = 3.459e-9 Identity = 21/33 (63.64%), Postives = 27/33 (81.82%), Query Frame = 3
Query: 945 QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
Q++++LWSDP+ GC N +RGGGCYFGPDVT
Sbjct: 443 QIVDILWSDPKTQEGCSPNLFRGGGCYFGPDVT 475
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Match: ENSORLT00000036394.1 (serine/threonine-protein phosphatase with EF-hands 2-like [Source:NCBI gene;Acc:101171918]) HSP 1 Score: 165.236 bits (417), Expect = 3.372e-45 Identity = 102/275 (37.09%), Postives = 159/275 (57.82%), Query Frame = 2
Query: 38 MGCKLS-SNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHN----NPERHFDVKCKFSKFNDILPPDK--QAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
MGC +S SN F ++ ++A +LIQ++YR+Y A+ E +R+ W I Q +EYS EQ QI + L + N + ER ++ + NDI + + + +I+ + ++G L +P+T + L++ +++ +L +R +++LLL +LR LPN+ IS +TICGD+HG +DL+ IF KN +PS PY+FNGDFVDRG S+E++ +L L P+ V+LNRGNHEDH +N RYGF KE+ KY+
Sbjct: 1 MGCGVSKSNQFHKHSR------------KAIRAAVLIQRWYRQYVARTEMRRRYTWNIFQSIEYSGEQAQIKLYNFLGYLMDNFTPSSSER--NLISHIFRENDICRDAEWERYFCYKNIEVPEV-YSGPHLTFPLTLEQAIGLLDAFRN-KKQLHSRYVLQLLLETWRLLRMLPNINRISTCHSKEVTICGDLHGQLEDLLLIFYKNGMPSLEKPYVFNGDFVDRGKDSIEILLILFSFLLIYPSDVYLNRGNHEDHIINLRYGFTKEVLTKYR 259 HSP 2 Score: 59.6918 bits (143), Expect = 1.846e-9 Identity = 29/57 (50.88%), Postives = 34/57 (59.65%), Query Frame = 3
Query: 873 SVRSTNGNRCYIYYVSCSFHHRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
SVRS N N + Q+L+LLWSDP NGCK N RGGGCY+GPD+T
Sbjct: 410 SVRSDNSN------------EEWRQILDLLWSDPMTQNGCKPNEVRGGGCYWGPDIT 454
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Match: ENSORLT00000000429.2 (serine/threonine-protein phosphatase with EF-hands 2-like [Source:NCBI gene;Acc:101171918]) HSP 1 Score: 141.354 bits (355), Expect = 8.698e-37 Identity = 86/225 (38.22%), Postives = 133/225 (59.11%), Query Frame = 2
Query: 185 KRKMIWKIHQLVEYSNEQNQILMQKLLSITLHN----NPERHFDVKCKFSKFNDILPPDK--QAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
+R+ W I Q +EYS EQ QI + L + N + ER ++ + NDI + + + +I+ + ++G L +P+T + L++ +++ +L +R +++LLL +LR LPN+ IS +TICGD+HG +DL+ IF KN +PS PY+FNGDFVDRG S+E++ +L L P+ V+LNRGNHEDH +N RYGF KE+ KY+
Sbjct: 2 RRRYTWNIFQSIEYSGEQAQIKLYNFLGYLMDNFTPSSSER--NLISHIFRENDICRDAEWERYFCYKNIEVPEV-YSGPHLTFPLTLEQAIGLLDAFRN-KKQLHSRYVLQLLLETWRLLRMLPNINRISTCHSKEVTICGDLHGQLEDLLLIFYKNGMPSLEKPYVFNGDFVDRGKDSIEILLILFSFLLIYPSDVYLNRGNHEDHIINLRYGFTKEVLTKYR 222 HSP 2 Score: 59.6918 bits (143), Expect = 1.910e-9 Identity = 29/57 (50.88%), Postives = 34/57 (59.65%), Query Frame = 3
Query: 873 SVRSTNGNRCYIYYVSCSFHHRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
SVRS N N + Q+L+LLWSDP NGCK N RGGGCY+GPD+T
Sbjct: 373 SVRSDNSN------------EEWRQILDLLWSDPMTQNGCKPNEVRGGGCYWGPDIT 417
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Match: ENSORLT00000039311.1 (serine/threonine-protein phosphatase with EF-hands 2-like [Source:NCBI gene;Acc:101171918]) HSP 1 Score: 129.798 bits (325), Expect = 1.112e-32 Identity = 67/149 (44.97%), Postives = 99/149 (66.44%), Query Frame = 2
Query: 395 HNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
++G L +P+T + L++ +++ +L +R +++LLL +LR LPN+ IS +TICGD+HG +DL+ IF KN +PS PY+FNGDFVDRG S+E++ +L L P+ V+LNRGNHEDH +N RYGF KE+ KY+
Sbjct: 112 YSGPHLTFPLTLEQAIGLLDAFRN-KKQLHSRYVLQLLLETWRLLRMLPNINRISTCHSKEVTICGDLHGQLEDLLLIFYKNGMPSLEKPYVFNGDFVDRGKDSIEILLILFSFLLIYPSDVYLNRGNHEDHIINLRYGFTKEVLTKYR 259 HSP 2 Score: 59.6918 bits (143), Expect = 2.271e-9 Identity = 29/57 (50.88%), Postives = 34/57 (59.65%), Query Frame = 3
Query: 873 SVRSTNGNRCYIYYVSCSFHHRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
SVRS N N + Q+L+LLWSDP NGCK N RGGGCY+GPD+T
Sbjct: 410 SVRSDNSN------------EEWRQILDLLWSDPMTQNGCKPNEVRGGGCYWGPDIT 454
BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Match: SMESG000003989.1 (SMESG000003989.1) HSP 1 Score: 624.394 bits (1609), Expect = 0.000e+0 Identity = 301/303 (99.34%), Postives = 303/303 (100.00%), Query Frame = 2
Query: 5 AYFEPKVWRPVMGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQYESDNMNECEINEWKQVLHIL 913
AYFEPKVWRPVMGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQYESDNMNECEINEWKQVL++L
Sbjct: 59 AYFEPKVWRPVMGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQYESDNMNECEINEWKQVLNLL 361 HSP 2 Score: 82.0333 bits (201), Expect = 6.949e-17 Identity = 39/59 (66.10%), Postives = 42/59 (71.19%), Query Frame = 3
Query: 870 MSVRSTNGNRCYIYYVSCSFHHRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVTL 1046
+ S N N C I + + QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVTL
Sbjct: 339 LQYESDNMNECEI--------NEWKQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVTL 389
BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Match: SMESG000003989.1 (SMESG000003989.1) HSP 1 Score: 623.239 bits (1606), Expect = 0.000e+0 Identity = 301/303 (99.34%), Postives = 303/303 (100.00%), Query Frame = 2
Query: 5 AYFEPKVWRPVMGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQYESDNMNECEINEWKQVLHIL 913
AYFEPKVWRPVMGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQYESDNMNECEINEWKQVL++L
Sbjct: 59 AYFEPKVWRPVMGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPVSITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYKFKSVLQYESDNMNECEINEWKQVLNLL 361 HSP 2 Score: 81.6481 bits (200), Expect = 8.340e-17 Identity = 39/59 (66.10%), Postives = 42/59 (71.19%), Query Frame = 3
Query: 870 MSVRSTNGNRCYIYYVSCSFHHRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVTL 1046
+ S N N C I + + QVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVTL
Sbjct: 339 LQYESDNMNECEI--------NEWKQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVTL 389
BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Match: SMESG000042202.1 (SMESG000042202.1) HSP 1 Score: 198.749 bits (504), Expect = 6.380e-58 Identity = 114/252 (45.24%), Postives = 154/252 (61.11%), Query Frame = 2
Query: 122 TLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQK----LLSITLHNNPERHFDVKCKFSKFNDILPP--------DKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
++KA +LIQ +YRRYRAK EAKR+ W I+Q +EYS EQ+Q+ +Q LLS+T + E +V SK + + D Q + + ++ ++ G KL +P++ V L+E ++ L R L+ELL + +L+ PNV + S +TICGD+HG DDLVTIF KN P TSNPY+ NGDFVDRGS SVE+ ++L FL P +VFLNRGNHEDH MN RYGF KE+ KYK
Sbjct: 48 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLT-NKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRK-EQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYK 297 HSP 2 Score: 62.7734 bits (151), Expect = 1.434e-10 Identity = 24/38 (63.16%), Postives = 29/38 (76.32%), Query Frame = 3
Query: 930 HHRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
+ Q+L+LLWSDPR GC +N YRGGGCYFGPD+T
Sbjct: 365 EEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDIT 402
BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Match: SMESG000042202.1 (SMESG000042202.1) HSP 1 Score: 197.978 bits (502), Expect = 7.375e-58 Identity = 114/252 (45.24%), Postives = 153/252 (60.71%), Query Frame = 2
Query: 122 TLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQK----LLSITLHNNPERHFDVKCKFSKFNDILPP--------DKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
+KA +LIQ +YRRYRAK EAKR+ W I+Q +EYS EQ+Q+ +Q LLS+T + E +V SK + + D Q + + ++ ++ G KL +P++ V L+E ++ L R L+ELL + +L+ PNV + S +TICGD+HG DDLVTIF KN P TSNPY+ NGDFVDRGS SVE+ ++L FL P +VFLNRGNHEDH MN RYGF KE+ KYK
Sbjct: 22 AIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLT-NKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRK-EQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYK 271 HSP 2 Score: 62.7734 bits (151), Expect = 1.525e-10 Identity = 24/38 (63.16%), Postives = 29/38 (76.32%), Query Frame = 3
Query: 930 HHRYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
+ Q+L+LLWSDPR GC +N YRGGGCYFGPD+T
Sbjct: 339 EEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDIT 376
BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Match: SMESG000076282.1 (SMESG000076282.1) HSP 1 Score: 179.874 bits (455), Expect = 3.711e-51 Identity = 99/270 (36.67%), Postives = 157/270 (58.15%), Query Frame = 2
Query: 38 MGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQKLLSITLHNNPERHFDVKCKFSKFNDILPPDKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNK--LSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELNNKYK 832
MGC+ S K N ++ + + + +K+V+ IQK+YR Y+A+ EA+RK W I+Q +EYS EQ+Q+ + ++ +++ F+K + K++ + + L+ ++G +++P+T ++ +L+ + NN+ L L ELL++ + +L+ PN+ E ITICGD+HG DL+ IF++N P SNPY+FNGDF+DRG SVE+ +L + P VFLNRGNHED MN RYGF KE+ KYK
Sbjct: 1 MGCQQSD--LKKNGIASVLLREDNEDLKMMKSVIAIQKWYRGYQARLEARRKCSWMIYQSIEYSGEQDQLKLHNFFLDLMNLMGQQNLSSDSLFTKALNKSTSIKRSSEYENDIPLETDYSGPIIQFPLTLTVITSLINAF---NNEQILHGHYLFELLVQTRGILKTKPNISETDLSIFKHITICGDLHGQLQDLIYIFEENRYPDPSNPYVFNGDFIDRGKHSVEIAVILFSFLILYPGCVFLNRGNHEDKIMNLRYGFIKEVQTKYK 265 HSP 2 Score: 63.5438 bits (153), Expect = 8.252e-11 Identity = 23/36 (63.89%), Postives = 30/36 (83.33%), Query Frame = 3
Query: 936 RYFQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVT 1043
+ QVL++LWSDP+P GC+ N +RGGGCYFGPD+T
Sbjct: 332 EWLQVLDILWSDPKPQKGCRQNLFRGGGCYFGPDIT 367 The following BLAST results are available for this feature:
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30007351 ID=SMED30007351|Name=Serine/threonine-protein phosphatase|organism=Schmidtea mediterranea sexual|type=transcript|length=1047bpback to top protein sequence of SMED30007351-orf-1 >SMED30007351-orf-1 ID=SMED30007351-orf-1|Name=SMED30007351-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=311bp MGCKLSSNLFKNNTNDDMIACKSSNIVATLKAVLLIQKYYRRYRAKCEAKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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