TBC1 domain family member 2B
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30007341 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of TBC1 domain family member 2B vs. Ensembl Human
Match: TBC1D30 (TBC1 domain family member 30 [Source:HGNC Symbol;Acc:HGNC:29164]) HSP 1 Score: 431.024 bits (1107), Expect = 9.654e-137 Identity = 228/478 (47.70%), Postives = 307/478 (64.23%), Query Frame = 2 Query: 455 RLVRQLKRRDHALAKM------QKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGG----MMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQY 1849 R R LKR+ + + +++C TA +L+ DTKLKF +EP G F+QW +A+K VARL G+P E R+KVWL+LA++++ DW++ ++F FNERSNPDDDS+G+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK VGYCQGFN+LAA+ILEVME NE D+LKIM+YL+D +LPESYF NL+ALS+DMAVFR+ L + +P+L+ HL+ LQ A+ + YEPPLTNVFTMQWFLTLFATCLP VL IWDS+ EGSEII R LAIW L +Q+ AD FY TM LT ++ + + Q L+ +Y+MAP PFP L+ LR+++TYNI PF P+ + G + D+DE+ D + ++GC G + P + KE SL S +I+++ PGA+++ S +H A ERM TD+ L+ QY Sbjct: 12 RGGRCLKRQGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRT-----ANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLAELREKYTYNITPF---PATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAPELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQY 481
BLAST of TBC1 domain family member 2B vs. Ensembl Human
Match: TBC1D30 (TBC1 domain family member 30 [Source:HGNC Symbol;Acc:HGNC:29164]) HSP 1 Score: 360.533 bits (924), Expect = 2.146e-111 Identity = 189/375 (50.40%), Postives = 247/375 (65.87%), Query Frame = 2 Query: 746 IKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGG----MMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQY 1849 ++F FNERSNPDDDS+G+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK VGYCQGFN+LAA+ILEVME NE D+LKIM+YL+D +LPESYF NL+ALS+DMAVFR+ L + +P+L+ HL+ LQ A+ + YEPPLTNVFTMQWFLTLFATCLP VL IWDS+ EGSEII R LAIW L +Q+ AD FY TM LT ++ + + Q L+ +Y+MAP PFP L+ LR+++TYNI PF P+ + G + D+DE+ D + ++GC G + P + KE SL S +I+++ PGA+++ S +H A ERM TD+ L+ QY Sbjct: 1 MRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRT-----ANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLAELREKYTYNITPF---PATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAPELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQY 367
BLAST of TBC1 domain family member 2B vs. Ensembl Human
Match: TBC1D30 (TBC1 domain family member 30 [Source:HGNC Symbol;Acc:HGNC:29164]) HSP 1 Score: 163.31 bits (412), Expect = 5.279e-44 Identity = 88/187 (47.06%), Postives = 119/187 (63.64%), Query Frame = 2 Query: 248 SWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIV 808 S DS T S SD V G R G S E + + L QK EL+ + +K + I S++L+R LK++D L K+Q+NCDI+TA LQA S KRR DTKLKF +EP G F+QW +A+K VARL G+P E R+KVWL+LA++++ DW++ ++F FNERSNPDDDS+G+QIV Sbjct: 114 SLDSSTEASGSDVVLGG--RSGAGDSRVLQELQERPSQRHQMLYLRQKDANELKTILRELKYRIGIQSAKLLRHLKQKDRLLHKVQRNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIV 298
BLAST of TBC1 domain family member 2B vs. Ensembl Human
Match: TBC1D30 (TBC1 domain family member 30 [Source:HGNC Symbol;Acc:HGNC:29164]) HSP 1 Score: 147.902 bits (372), Expect = 2.362e-41 Identity = 66/91 (72.53%), Postives = 79/91 (86.81%), Query Frame = 2 Query: 746 IKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVD 1009 ++F FNERSNPDDDS+G+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK VGYCQGFN+LAA+ILEVME NE D+LKIM+YL+D Sbjct: 1 MRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMIYLID 91
BLAST of TBC1 domain family member 2B vs. Ensembl Human
Match: TBC1D2 (TBC1 domain family member 2 [Source:HGNC Symbol;Acc:HGNC:18026]) HSP 1 Score: 119.783 bits (299), Expect = 8.204e-28 Identity = 89/288 (30.90%), Postives = 140/288 (48.61%), Query Frame = 2 Query: 650 LPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCD----TFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYN-MAPMPFPGLSNLR 1498 L G+P E R +VW L H+ VQ + + R + QI DL+RT + T T S L+RVLLA++ N +GYCQG N LAAI L V+E EE + +V +V+ I+P Y+ L A +D V ++ L+ +P+L AH + +H + L T WFL +FA L +++L +WD+ + EG++++FR LAI++ ++L++ + Y +R T +S+ L+N +N M P L LR Sbjct: 162 LRAGVPREHRPRVWRWLV--HLRVQHLHTPGCYQELLS-RGQAREHPAARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLE-EEESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAH---------------LGQHHVDLSLV---TFNWFLVVFADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLEIYQYLRFFTKTISNS-----RKLMNIAFNDMNPFRMKQLRQLR 422
BLAST of TBC1 domain family member 2B vs. Ensembl Celegans
Match: tbc-2 (TBC (Tre-2/Bub2/Cdc16) domain family [Source:UniProtKB/TrEMBL;Acc:Q23419]) HSP 1 Score: 102.834 bits (255), Expect = 5.805e-22 Identity = 71/241 (29.46%), Postives = 121/241 (50.21%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYD-----WNRVIKFAFNERSNPDDDSLGLQIVKDLHRT-GCDTFATESERA---ILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLK 1354 G+P R +VW + + + ++ + + +++ A ++ + D+ QI DL RT + E + A L+ VL A+ N VGYCQG N LAAI L + +E+DS +V V+H+ PE Y+ +L D V R+ + +PKLAAHL L++ ++F + WFLT F LP + L I+D+ + EG++++FR LA++++ +L+ Sbjct: 630 GVPPAYRGRVWKIIVTHWVKDKQAELGNGYYQSMLRKAGTKKQDGSYDAAIKQIDLDLARTLPTNKLFDEPDSANIEKLRNVLYAFRYHNSHVGYCQGLNRLAAIAL--LNLDEQDSFWFLVACVEHLQPEGYYTSSLIGAVADQKVLRDLVAEKLPKLAAHLRALEVDL------------------SLFALSWFLTCFVDVLPHSIYLTIFDAFLYEGNKVLFRFALALFKICEPHVLQ 850
BLAST of TBC1 domain family member 2B vs. Ensembl Celegans
Match: tbc-2 (TBC (Tre-2/Bub2/Cdc16) domain family [Source:UniProtKB/TrEMBL;Acc:Q23419]) HSP 1 Score: 102.834 bits (255), Expect = 5.805e-22 Identity = 71/241 (29.46%), Postives = 121/241 (50.21%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYD-----WNRVIKFAFNERSNPDDDSLGLQIVKDLHRT-GCDTFATESERA---ILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLK 1354 G+P R +VW + + + ++ + + +++ A ++ + D+ QI DL RT + E + A L+ VL A+ N VGYCQG N LAAI L + +E+DS +V V+H+ PE Y+ +L D V R+ + +PKLAAHL L++ ++F + WFLT F LP + L I+D+ + EG++++FR LA++++ +L+ Sbjct: 630 GVPPAYRGRVWKIIVTHWVKDKQAELGNGYYQSMLRKAGTKKQDGSYDAAIKQIDLDLARTLPTNKLFDEPDSANIEKLRNVLYAFRYHNSHVGYCQGLNRLAAIAL--LNLDEQDSFWFLVACVEHLQPEGYYTSSLIGAVADQKVLRDLVAEKLPKLAAHLRALEVDL------------------SLFALSWFLTCFVDVLPHSIYLTIFDAFLYEGNKVLFRFALALFKICEPHVLQ 850
BLAST of TBC1 domain family member 2B vs. Ensembl Celegans
Match: tbc-19 (TBC (Tre-2/Bub2/Cdc16) domain family [Source:UniProtKB/TrEMBL;Acc:G5EEB5]) HSP 1 Score: 92.8189 bits (229), Expect = 9.083e-19 Identity = 65/245 (26.53%), Postives = 109/245 (44.49%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHI-----TVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDT--FATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDA 1366 G+P+ +R VW L N + KY + + E D QI DL RT + F + + + + L +VL A+ N ++GYCQG N LAA L + ED+ ++ + + ++YF NL D V + L + PK+ HL +L + FT+ WF++LF +P + +L IWD +LEG +++FR + + ++++ DA Sbjct: 451 GIPNSLRATVWKILINQQVEDLKNVYGKYYYRNLCNIQGGEDEKTYSDVHQKQINLDLLRTMPNNVHFMSANSKGVTQLLQVLHAFCLHNSQIGYCQGMNFLAATALLFV--GPEDAFWFLIAVTERYFDKTYFDSNLTGAQADQEVLKGLLEVQHPKIMKHLKSLDIDVAS------------------FTLNWFISLFFDAVPFNTLLRIWDCFLLEGPKVLFRFAIVLIGKHEEEIISRGDA 675
BLAST of TBC1 domain family member 2B vs. Ensembl Celegans
Match: tbc-18 (TBC (Tre-2/Bub2/Cdc16) domain family [Source:UniProtKB/TrEMBL;Acc:Q94222]) HSP 1 Score: 88.5817 bits (218), Expect = 1.252e-17 Identity = 68/242 (28.10%), Postives = 114/242 (47.11%), Query Frame = 2 Query: 659 GLPSEIRKKVW--LSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDT--FATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDA 1366 G+P +R +W LS A KY + V+ ++ D S+G+QI +DL RT + F ++ I L+R+L A +GYCQG V+ A +L + +EE + +M L++ ILP +++ Q L L D V R + HVP L L YE ++ + T+ W LTLF + ++L +WD I G IFR ++I ++ +++++ + Sbjct: 150 GIPHSMRPFLWPRLSGATKKQKDAKYTYESVL-----QQCAQDKPSIGVQIERDLLRTLPNNICFWKKNSEGIEALRRILKCVAFIYPDLGYCQGMGVIVATLL--LYCSEETTFWMMTALIEDILPPNFYTQTLLGLQADERVSRHLMKCHVPDLNKAL-----------------EDYEVEVS-LLTVSWLLTLFGSVFRTRVMLRVWDFIFYSGGVNIFRVIISILKMKEQEIVEIAET 366
BLAST of TBC1 domain family member 2B vs. Ensembl Celegans
Match: tbc-6 (Growth hormone-regulated TBC protein 6 [Source:UniProtKB/Swiss-Prot;Acc:Q09445]) HSP 1 Score: 83.9593 bits (206), Expect = 4.525e-17 Identity = 65/224 (29.02%), Postives = 98/224 (43.75%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDT--FATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAI 1324 G+P RK++WL + W R + D + QI DL RT D TE R L R L A A VGYCQG N +A +IL V+ +E ++ ++V+LV + Y+ +N+ L DM V L H P++ L L + ++ +WF+ F LP + VL +WD ++ EG E +FR +A+ Sbjct: 78 GIPHTFRKELWLRSCPSR---ADGVWQR----------HEVPDEVIKQIKLDLPRTFPDNKFLKTEGTRKTLGRALFAVAEHIPSVGYCQGLNFVAGVILLVVN-DESRAIDLLVHLVSQ--RQEYYGKNMIGLRRDMHVLHSLLREHCPRVVVTLEKLDVG------------------LDMLVGKWFVCWFVESLPMETVLRLWDCLIYEGDEWLFRIAVAL 267
BLAST of TBC1 domain family member 2B vs. Ensembl Fly
Match: CG42795 (gene:FBgn0261928 transcript:FBtr0345170) HSP 1 Score: 304.679 bits (779), Expect = 1.555e-85 Identity = 144/309 (46.60%), Postives = 198/309 (64.08%), Query Frame = 2 Query: 611 FRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTG---CDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPF 1528 + QW AMK VARLP G P E R+K+WLSLA+ ++ + DW + + F E DD+ LG+QIVKDLHRTG C A +A LKR+LL YAR+N VGYCQGFN+L A+IL+VM++ EE+S+K+M+YLV+ +LP YF ++ L DM VFRE + +P+LA HL LQ N +EPPLTNVFTMQWFLT+F TCLP VL +WD +++EGS+++ RT L +W LL ++++ V AD FY M +++L +G + + LI R+ + P+ L LRD+ YNI P Sbjct: 205 YNQWLHAMKLVARLPGGTPPEFRRKLWLSLADKYLKSKNVDWAQQREKCFCEEWREDDEELGIQIVKDLHRTGSNLCTGPAGSINQAKLKRILLGYARYNPEVGYCQGFNMLGALILQVMDKEEEESMKVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAKHLQRLQGPV---------ENAFEPPLTNVFTMQWFLTMFCTCLPMSCVLRVWDLVLIEGSDVLLRTALVLWSLLEERVISVRSADEFYGKMGSYSSELLNGHLVDSNGLIERVVKLGPI--EDLRQLRDKHLYNIAPL 502
BLAST of TBC1 domain family member 2B vs. Ensembl Fly
Match: CG42795 (gene:FBgn0261928 transcript:FBtr0332437) HSP 1 Score: 304.294 bits (778), Expect = 1.828e-85 Identity = 144/309 (46.60%), Postives = 198/309 (64.08%), Query Frame = 2 Query: 611 FRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTG---CDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPF 1528 + QW AMK VARLP G P E R+K+WLSLA+ ++ + DW + + F E DD+ LG+QIVKDLHRTG C A +A LKR+LL YAR+N VGYCQGFN+L A+IL+VM++ EE+S+K+M+YLV+ +LP YF ++ L DM VFRE + +P+LA HL LQ N +EPPLTNVFTMQWFLT+F TCLP VL +WD +++EGS+++ RT L +W LL ++++ V AD FY M +++L +G + + LI R+ + P+ L LRD+ YNI P Sbjct: 205 YNQWLHAMKLVARLPGGTPPEFRRKLWLSLADKYLKSKNVDWAQQREKCFCEEWREDDEELGIQIVKDLHRTGSNLCTGPAGSINQAKLKRILLGYARYNPEVGYCQGFNMLGALILQVMDKEEEESMKVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAKHLQRLQGPV---------ENAFEPPLTNVFTMQWFLTMFCTCLPMSCVLRVWDLVLIEGSDVLLRTALVLWSLLEERVISVRSADEFYGKMGSYSSELLNGHLVDSNGLIERVVKLGPI--EDLRQLRDKHLYNIAPL 502
BLAST of TBC1 domain family member 2B vs. Ensembl Fly
Match: CG42795 (gene:FBgn0261928 transcript:FBtr0303601) HSP 1 Score: 303.908 bits (777), Expect = 2.435e-85 Identity = 144/309 (46.60%), Postives = 198/309 (64.08%), Query Frame = 2 Query: 611 FRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTG---CDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPF 1528 + QW AMK VARLP G P E R+K+WLSLA+ ++ + DW + + F E DD+ LG+QIVKDLHRTG C A +A LKR+LL YAR+N VGYCQGFN+L A+IL+VM++ EE+S+K+M+YLV+ +LP YF ++ L DM VFRE + +P+LA HL LQ N +EPPLTNVFTMQWFLT+F TCLP VL +WD +++EGS+++ RT L +W LL ++++ V AD FY M +++L +G + + LI R+ + P+ L LRD+ YNI P Sbjct: 205 YNQWLHAMKLVARLPGGTPPEFRRKLWLSLADKYLKSKNVDWAQQREKCFCEEWREDDEELGIQIVKDLHRTGSNLCTGPAGSINQAKLKRILLGYARYNPEVGYCQGFNMLGALILQVMDKEEEESMKVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAKHLQRLQGPV---------ENAFEPPLTNVFTMQWFLTMFCTCLPMSCVLRVWDLVLIEGSDVLLRTALVLWSLLEERVISVRSADEFYGKMGSYSSELLNGHLVDSNGLIERVVKLGPI--EDLRQLRDKHLYNIAPL 502
BLAST of TBC1 domain family member 2B vs. Ensembl Fly
Match: CG42795 (gene:FBgn0261928 transcript:FBtr0345169) HSP 1 Score: 303.908 bits (777), Expect = 2.503e-85 Identity = 144/309 (46.60%), Postives = 198/309 (64.08%), Query Frame = 2 Query: 611 FRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTG---CDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPF 1528 + QW AMK VARLP G P E R+K+WLSLA+ ++ + DW + + F E DD+ LG+QIVKDLHRTG C A +A LKR+LL YAR+N VGYCQGFN+L A+IL+VM++ EE+S+K+M+YLV+ +LP YF ++ L DM VFRE + +P+LA HL LQ N +EPPLTNVFTMQWFLT+F TCLP VL +WD +++EGS+++ RT L +W LL ++++ V AD FY M +++L +G + + LI R+ + P+ L LRD+ YNI P Sbjct: 205 YNQWLHAMKLVARLPGGTPPEFRRKLWLSLADKYLKSKNVDWAQQREKCFCEEWREDDEELGIQIVKDLHRTGSNLCTGPAGSINQAKLKRILLGYARYNPEVGYCQGFNMLGALILQVMDKEEEESMKVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAKHLQRLQGPV---------ENAFEPPLTNVFTMQWFLTMFCTCLPMSCVLRVWDLVLIEGSDVLLRTALVLWSLLEERVISVRSADEFYGKMGSYSSELLNGHLVDSNGLIERVVKLGPI--EDLRQLRDKHLYNIAPL 502
BLAST of TBC1 domain family member 2B vs. Ensembl Fly
Match: CG42795 (gene:FBgn0261928 transcript:FBtr0303602) HSP 1 Score: 303.908 bits (777), Expect = 2.726e-85 Identity = 144/309 (46.60%), Postives = 198/309 (64.08%), Query Frame = 2 Query: 611 FRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTG---CDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPF 1528 + QW AMK VARLP G P E R+K+WLSLA+ ++ + DW + + F E DD+ LG+QIVKDLHRTG C A +A LKR+LL YAR+N VGYCQGFN+L A+IL+VM++ EE+S+K+M+YLV+ +LP YF ++ L DM VFRE + +P+LA HL LQ N +EPPLTNVFTMQWFLT+F TCLP VL +WD +++EGS+++ RT L +W LL ++++ V AD FY M +++L +G + + LI R+ + P+ L LRD+ YNI P Sbjct: 84 YNQWLHAMKLVARLPGGTPPEFRRKLWLSLADKYLKSKNVDWAQQREKCFCEEWREDDEELGIQIVKDLHRTGSNLCTGPAGSINQAKLKRILLGYARYNPEVGYCQGFNMLGALILQVMDKEEEESMKVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAKHLQRLQGPV---------ENAFEPPLTNVFTMQWFLTMFCTCLPMSCVLRVWDLVLIEGSDVLLRTALVLWSLLEERVISVRSADEFYGKMGSYSSELLNGHLVDSNGLIERVVKLGPI--EDLRQLRDKHLYNIAPL 381
BLAST of TBC1 domain family member 2B vs. Ensembl Zebrafish
Match: tbc1d30 (TBC1 domain family, member 30 [Source:ZFIN;Acc:ZDB-GENE-030131-2064]) HSP 1 Score: 492.656 bits (1267), Expect = 4.782e-157 Identity = 284/644 (44.10%), Postives = 399/644 (61.96%), Query Frame = 2 Query: 149 FEKHECKNS-GESVIDNLLFEIYDKWAYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHLSNYKA--KENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYXXXXXXXXXTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTASHIIVSS----TYPSLQNSMVNH 2050 F++ E K+S S++D LL E+YD +++ DS T S+SDA G RS S E + KH L QK EEL+ + +K +A+ S++LVRQ KR+D K QKNCDI+TA LQA S KRR DT+LKF +EP G F+QW +A+K VARLP+G+P E RK+VWL+LA+ ++ DW + ++FAFN+RSNPDDDSLG+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK VGYCQGFNVLAA+ILEV E NE D+LK+M+YL+D +LP+SYFA NL+ALS+DMAVFR+ L + +P+L+ HL++LQ + ++ YEPPLTNVFTMQWFLT+FATCLP VL IWDS+ EGSE++ R LAIW L +++ + AD FY M CLT ++ + + + L+ +Y+MAP PFP L+ LR+++TYNI PF P+ + + S E D D D D + V G + + + Y+ K+ + S + +++++ PGAV + H A ERM TD+ L+ QY +IK KQ++ + L+ H + VLA S +G P+P +H+++ SL+N M+++ Sbjct: 75 FDREELKDSRASSLVDCLLVELYDTYSHGV---PGLDSSTEASSSDAFLG----RSNSGSSFLQELQEKHTRRHQVKYLAQKGPEELKWIVQEVKYRIAVQSAKLVRQAKRKDRLRQKFQKNCDIVTACLQAVSQKRRVDTRLKFTIEPSLGKNGFQQWYDALKAVARLPVGIPKEWRKRVWLTLADQYLHSISIDWEKTMRFAFNDRSNPDDDSLGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNVLAALILEVTEGNEGDALKVMIYLIDKVLPDSYFANNLRALSVDMAVFRDLLRLKLPELSQHLHHLQKVANREAGGS-----YEPPLTNVFTMQWFLTMFATCLPHHTVLKIWDSVFFEGSEMLLRVALAIWAKLGERIEECQTADEFYSIMGCLTQEMLEHKLIDSNELMQTVYSMAPFPFPQLAELREKYTYNITPF---PAPVRANSSLALHGWESDDDADMDDEDSIVTALGCLGPLGGLLAPEIQRYQRHLKDQRAEQSCNGSNMAELSPGAVGAGRAEHQAAINSMMLERMSTDISALKKQYSRIKQKQQQQAGLL--YIHTDKCPATSVLA--------SQIG-PSPVVNHLLLGRRPRPCERSLKNGMIHN 692
BLAST of TBC1 domain family member 2B vs. Ensembl Zebrafish
Match: tbc1d2 (TBC1 domain family, member 2 [Source:ZFIN;Acc:ZDB-GENE-140106-100]) HSP 1 Score: 128.642 bits (322), Expect = 9.176e-30 Identity = 81/265 (30.57%), Postives = 138/265 (52.08%), Query Frame = 2 Query: 632 MKGVARLPLGLPSEIRKKVWLSLANNHI-TVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDG 1417 MKG+ R GLP E R +VW + ++++ +R + RS+P +Q+ D T F+ + I L+RVL A++ N +GY QG N LAAI L V++ E D+ +V +V+HI+P +YF ++L D V ++ + +P+L AHL L++ ++ T++WFL LF LP ++ +WD+++ EGS++IFR LA+++ + +LK+ D+ Y +R N ++DG Sbjct: 616 MKGLLRT--GLPHEYRVRVWRFMIQTRTKSLRERHPDRYHELCEKSRSSPHLVPRQIQLDLDRTLTSNKHFSPPTSPLIQKLERVLQAFSWHNPTIGYVQGLNRLAAIALLVLQ-EEADAFWCLVVIVEHIMPPNYFTKDLVGCQADQRVLKDLMLEKLPRLTAHLEALKVD------------------ISLITVEWFLVLFVESLPTRILFKVWDALLYEGSKVIFRYALALFKYREEAILKIQDSVEMYQYLRIFPNTIADG 859
BLAST of TBC1 domain family member 2B vs. Ensembl Zebrafish
Match: sgsm3 (small G protein signaling modulator 3 [Source:NCBI gene;Acc:406635]) HSP 1 Score: 110.923 bits (276), Expect = 2.368e-24 Identity = 74/257 (28.79%), Postives = 128/257 (49.81%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRT----GCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDG 1417 G+P +R ++W+ L+ +QK + + + S+ DD + QI KDL RT C T L+RVL A +GYCQG ++ + +L +E EED+L +M L++ +LP SYF+ L + D V R+ + ++P+L + + E ++ T+ WFLT FA+ + ++L IWD + EGS ++F+ L + ++ D+L+ ++ S + T+ L +QL DG Sbjct: 115 GIPHSMRPQLWMRLSG---ALQKKRTSDISYREIVKNSSNDDTTAAKQIEKDLLRTMPTNACFNTLTSVGVPKLRRVLRGLAWLYPDIGYCQGTGMVVSCLLLFLE--EEDALWMMCALIEDLLPPSYFSSTLLGVQTDQRVLRQLIVQYLPRLD---------------KLLQEHDIE---LSLITLHWFLTAFASVVDIRILLRIWDLLFYEGSMVLFQVTLGMLKIKEDELVSSENSASIFNTLSDLPSQLEDG 348
BLAST of TBC1 domain family member 2B vs. Ensembl Zebrafish
Match: grtp1b (growth hormone regulated TBC protein 1b [Source:ZFIN;Acc:ZDB-GENE-050417-346]) HSP 1 Score: 101.293 bits (251), Expect = 1.899e-22 Identity = 73/254 (28.74%), Postives = 121/254 (47.64%), Query Frame = 2 Query: 614 RQWCEAMKGVARLPL----------GLPSEIRKKVWLSL--ANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDT--FATESERAILK---RVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAI 1324 ++W + ++G ++ G+P E R ++W++ A + + + ++K E+ +P + + I D+HRT D F S+ + K VLLAY NK VGYCQG N +A +L ++ ++EE S +M L+ ILP+ Y+ Q + L +D V E + VP A N ++ T V + +WF+ L+ LP + VL IWD + EGS+I+FR L + Sbjct: 54 KKWSKLLQGTGKMEKNLKVKRYVRKGIPCEHRTEIWMAFSGAQDQLERNPGYYQALLK---TEQHDPKIEEV---IHADMHRTFPDNIQFRHSSQSCLQKALFNVLLAYGHHNKDVGYCQGMNFIAGYLL-IITKDEEKSFWLMDALIGRILPD-YYTQTMLGLKVDQEVLGELVKSKVP-----------------AVWQTMNQHDVMWTLVVS-RWFICLYVDVLPVETVLRIWDCLFYEGSKILFRVALTL 281
BLAST of TBC1 domain family member 2B vs. Ensembl Zebrafish
Match: tbc1d2b (TBC1 domain family, member 2B [Source:ZFIN;Acc:ZDB-GENE-100922-148]) HSP 1 Score: 103.99 bits (258), Expect = 4.126e-22 Identity = 80/290 (27.59%), Postives = 136/290 (46.90%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHIT----VQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDL----HRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDG--LIAQPDHLINRIYNMAPMPFPGLSNLR 1498 G+P R KVW + H+ Q D+ + N++ NP + L +++ L H + D+ + L+ VLLA++ N +GYCQG N LAAI L + ++ED+ +V +V+ +P Y+ + L +D VF++ + +P+L AH HY+ + + T WFL +F + D++ IWDS + EG +IIFR LA+++ ++ LK+ D + + +R T + D L+A +M P P + N R Sbjct: 537 GVPHIHRSKVWSWCVSFHVKKMRDCQPKDYYHNLLCMANDKPNPACKQIELDLLRTLPNNKHYSSPDSDGIQK----LRNVLLAFSWRNPDIGYCQGLNRLAAIALLYL--DQEDAFWCLVAIVEVFMPHDYYTKTLLGSQVDQRVFKDLMYEKLPRLHAHF-----------------EHYKVDFS-LITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKIIFRFALALFKYKEEEFLKLQDPMTIFKYLRYFTRTILDARKLMAMA------FVDMNPFPLRQIQNRR 796
BLAST of TBC1 domain family member 2B vs. Ensembl Xenopus
Match: bard1 (BRCA1 associated RING domain 1 [Source:Xenbase;Acc:XB-GENE-492035]) HSP 1 Score: 504.597 bits (1298), Expect = 9.148e-163 Identity = 277/655 (42.29%), Postives = 396/655 (60.46%), Query Frame = 2 Query: 155 KHECKNSGESVIDNLLFEIYDKW-----AYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGG----MMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYXXXXXXXXXTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSV----GRPNPTASHIIVSSTYPSLQNS--MVNHLFLTR 2065 + + ++ S+++ LL E+YD + Y R S DS T S SDA + S G SE + + + L QK EL+ +K + + +AI S++L+RQ+K++D K+QKNCDI+TA LQA S KRR DTKLKF +EP G F+QW +A+K VARLP G+P E RK+VWL+LA++++ DW++ ++F FN+RSNPDDDS+G+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK +GYCQGFN+LAA+ILEVME NE D+LK+M+YL+D +LP+SYFA NL+ALS+DMAVFR+ + + +P+L+ H L Q+ A+ + YEPPLTNVFTMQWFLTLFATCLP VL IWDS+ EGSEI+ R LAIW L +Q+ ++D FY TM LT ++ + + + L+ +Y+MA PFP L+ LR+++TYNI PF P+ + S G + D+DE+ + VN ++GC G + P + K+ + SL + +I+++ PGA+ + S +H ERM TD+ L+ QY + I ++ +QV + HG+ K+S R VS PS N+ ++NHL L + Sbjct: 84 QQQGRSRTSSLVNGLLTELYDTYRGGAGCYYFRQQDSVDSSTEASGSDAFLSRSNPES-GFLQELSERQSSRHQML---YLKQKDCSELKAIKDELNRRIAIQSAKLLRQVKQKDRLQHKVQKNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWYDALKAVARLPTGIPKEWRKRVWLTLADHYLHSISIDWDKTMRFTFNDRSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTIGYCQGFNILAALILEVMEGNEGDALKVMIYLIDKVLPDSYFANNLRALSVDMAVFRDLVRMKLPELSQH-----LDVLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEILLRVSLAIWAKLGEQIECCQNSDDFYSTMGRLTQEMLEDSLIDSNELMQTVYSMAQFPFPQLAELREKYTYNITPF---PAPVKSASFSGRTSKMRDSDEENEIDEDDVNANAVGCLGPFSGFLAPELQKYQKQIKDQKEEQSLKASNIAELSPGAIDSCRSEYHAVFNSMMMERMTTDINALKQQY--------------SRIKKRQLQQINQVYIAAGHGEEKASAIPFDPRDQQNTDKGPVSCILPSQVNNSPVINHLLLGK 712
BLAST of TBC1 domain family member 2B vs. Ensembl Xenopus
Match: bard1 (BRCA1 associated RING domain 1 [Source:Xenbase;Acc:XB-GENE-492035]) HSP 1 Score: 499.204 bits (1284), Expect = 7.338e-161 Identity = 260/577 (45.06%), Postives = 368/577 (63.78%), Query Frame = 2 Query: 155 KHECKNSGESVIDNLLFEIYDKW-----AYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGG----MMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQY 1849 + + ++ S+++ LL E+YD + Y R S DS T S SDA + S G SE + + + L QK EL+ +K + + +AI S++L+RQ+K++D K+QKNCDI+TA LQA S KRR DTKLKF +EP G F+QW +A+K VARLP G+P E RK+VWL+LA++++ DW++ ++F FN+RSNPDDDS+G+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK +GYCQGFN+LAA+ILEVME NE D+LK+M+YL+D +LP+SYFA NL+ALS+DMAVFR+ + + +P+L+ H L Q+ A+ + YEPPLTNVFTMQWFLTLFATCLP VL IWDS+ EGSEI+ R LAIW L +Q+ ++D FY TM LT ++ + + + L+ +Y+MA PFP L+ LR+++TYNI PF P+ + S G + D+DE+ + VN ++GC G + P + K+ + SL + +I+++ PGA+ + S +H ERM TD+ L+ QY Sbjct: 84 QQQGRSRTSSLVNGLLTELYDTYRGGAGCYYFRQQDSVDSSTEASGSDAFLSRSNPES-GFLQELSERQSSRHQML---YLKQKDCSELKAIKDELNRRIAIQSAKLLRQVKQKDRLQHKVQKNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWYDALKAVARLPTGIPKEWRKRVWLTLADHYLHSISIDWDKTMRFTFNDRSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTIGYCQGFNILAALILEVMEGNEGDALKVMIYLIDKVLPDSYFANNLRALSVDMAVFRDLVRMKLPELSQH-----LDVLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEILLRVSLAIWAKLGEQIECCQNSDDFYSTMGRLTQEMLEDSLIDSNELMQTVYSMAQFPFPQLAELREKYTYNITPF---PAPVKSASFSGRTSKMRDSDEENEIDEDDVNANAVGCLGPFSGFLAPELQKYQKQIKDQKEEQSLKASNIAELSPGAIDSCRSEYHAVFNSMMMERMTTDINALKQQY 648
BLAST of TBC1 domain family member 2B vs. Ensembl Xenopus
Match: bard1 (BRCA1 associated RING domain 1 [Source:Xenbase;Acc:XB-GENE-492035]) HSP 1 Score: 434.876 bits (1117), Expect = 2.196e-138 Identity = 220/475 (46.32%), Postives = 310/475 (65.26%), Query Frame = 2 Query: 464 RQLKRRDHALAKM------QKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGG----MMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQY 1849 R LKR++ + + ++NC TA +L+ DTKLKF +EP G F+QW +A+K VARLP G+P E RK+VWL+LA++++ DW++ ++F FN+RSNPDDDS+G+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK +GYCQGFN+LAA+ILEVME NE D+LK+M+YL+D +LP+SYFA NL+ALS+DMAVFR+ + + +P+L+ HL+ LQ A+ + YEPPLTNVFTMQWFLTLFATCLP VL IWDS+ EGSEI+ R LAIW L +Q+ ++D FY TM LT ++ + + + L+ +Y+MA PFP L+ LR+++TYNI PF P+ + S G + D+DE+ + VN ++GC G + P + K+ + SL + +I+++ PGA+ + S +H ERM TD+ L+ QY Sbjct: 15 RCLKRKNTGVGNILSKVLKKRNCISRTAPRLLCTLEPGVDTKLKFTLEPSLGQNGFQQWYDALKAVARLPTGIPKEWRKRVWLTLADHYLHSISIDWDKTMRFTFNDRSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTIGYCQGFNILAALILEVMEGNEGDALKVMIYLIDKVLPDSYFANNLRALSVDMAVFRDLVRMKLPELSQHLDVLQRT-----ANKESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEILLRVSLAIWAKLGEQIECCQNSDDFYSTMGRLTQEMLEDSLIDSNELMQTVYSMAQFPFPQLAELREKYTYNITPF---PAPVKSASFSGRTSKMRDSDEENEIDEDDVNANAVGCLGPFSGFLAPELQKYQKQIKDQKEEQSLKASNIAELSPGAIDSCRSEYHAVFNSMMMERMTTDINALKQQY 481
BLAST of TBC1 domain family member 2B vs. Ensembl Xenopus
Match: cfap52 (cilia and flagella associated protein 52 [Source:Xenbase;Acc:XB-GENE-989292]) HSP 1 Score: 116.701 bits (291), Expect = 6.812e-26 Identity = 85/295 (28.81%), Postives = 147/295 (49.83%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYD-----WNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPM---PFPGLSNLRDRFTYNI 1519 G+P E R ++W N HI K + + +++ A E+ NP + L +++ L T T L+ VLLAY+ N +GYCQG N LAAI L + ++ED+ +V +V+ +P Y+ + L +D VF++ +N +P+L AH Y+ T + T WFL +F + D++ IWDS++ EGS++IFR L +++ +++LK+ D+ S + +R + + D ++ N+A + PFP L +R+R TY++ Sbjct: 573 GIPHEHRSRMWKWFTNLHIKKLKDEAAPGYFQSLLQNAL-EKQNPASKQIELDLMRTLPNNKHYTSPTSEGIQKLRNVLLAYSWRNPDIGYCQGINRLAAIALLYL--DQEDAFWCLVTIVEAFMPRDYYTKTLLGSQVDQRVFKDLMNEKLPRLCAHF-----------------EQYKVDYT-LITFNWFLVVFVDSVVSDILFRIWDSLLYEGSKVIFRFALGLFKYKEEEILKLQDSMSIFKYLRYFSRTILDA---------RKLCNIAFVDMNPFP-LRQIRNRRTYHL 836
BLAST of TBC1 domain family member 2B vs. Ensembl Xenopus
Match: cfap52 (cilia and flagella associated protein 52 [Source:Xenbase;Acc:XB-GENE-989292]) HSP 1 Score: 116.316 bits (290), Expect = 9.277e-26 Identity = 85/295 (28.81%), Postives = 147/295 (49.83%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYD-----WNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPM---PFPGLSNLRDRFTYNI 1519 G+P E R ++W N HI K + + +++ A E+ NP + L +++ L T T L+ VLLAY+ N +GYCQG N LAAI L + ++ED+ +V +V+ +P Y+ + L +D VF++ +N +P+L AH Y+ T + T WFL +F + D++ IWDS++ EGS++IFR L +++ +++LK+ D+ S + +R + + D ++ N+A + PFP L +R+R TY++ Sbjct: 642 GIPHEHRSRMWKWFTNLHIKKLKDEAAPGYFQSLLQNAL-EKQNPASKQIELDLMRTLPNNKHYTSPTSEGIQKLRNVLLAYSWRNPDIGYCQGINRLAAIALLYL--DQEDAFWCLVTIVEAFMPRDYYTKTLLGSQVDQRVFKDLMNEKLPRLCAHF-----------------EQYKVDYT-LITFNWFLVVFVDSVVSDILFRIWDSLLYEGSKVIFRFALGLFKYKEEEILKLQDSMSIFKYLRYFSRTILDA---------RKLCNIAFVDMNPFP-LRQIRNRRTYHL 905
BLAST of TBC1 domain family member 2B vs. Ensembl Mouse
Match: Tbc1d30 (TBC1 domain family, member 30 [Source:MGI Symbol;Acc:MGI:1921944]) HSP 1 Score: 431.795 bits (1109), Expect = 4.739e-137 Identity = 222/456 (48.68%), Postives = 302/456 (66.23%), Query Frame = 2 Query: 503 QKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGM--MPSNHLSNYKA--KENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQY 1849 +++C TA +L+ DTKLKF +EP G F+QW +A+K VARL G+P E R+KVWL+LA++++ DW++ ++F FNERSNPDDDS+G+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK VGYCQGFN+LAA+ILEVME NE D+LKIM+YL+D +LPESYF NL+ALS+DMAVFR+ L + +P+L+ HL+ LQ A+ + YEPPLTNVFTMQWFLTLFATCLP VL IWDS+ EGSEII R LAIW L +Q+ AD FY TM LT ++ + + Q L+ +Y+MAP PFP L+ LR+++TYNI PF P+ I G + D+D++ + +++GC G + + + L Y+ KE +L S +I+++ PGA+++ S +H A ERM TD+ L+ QY Sbjct: 35 KRSCISRTAPRLLCTLEPGVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKNVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRLKLPELSQHLDTLQRT-----ANKESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYGTMGRLTQEMLEQDLLQSHELMQTVYSMAPFPFPQLAELREKYTYNITPF---PATIKPTSVSGRHSKARDSDDENGPDDEDAVASAVGCLGPLSGLLAPELQKYQKQIKEATEEQTLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQY 482
BLAST of TBC1 domain family member 2B vs. Ensembl Mouse
Match: Tbc1d30 (TBC1 domain family, member 30 [Source:MGI Symbol;Acc:MGI:1921944]) HSP 1 Score: 190.66 bits (483), Expect = 1.680e-54 Identity = 99/201 (49.25%), Postives = 132/201 (65.67%), Query Frame = 2 Query: 248 SWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATE 850 S DS T TS SDA F R G S E + + L +K EL+ V +K + I S++L+RQLK++D L K+QKNCDI+TA LQA S KRR DTKLKF +EP G F+QW +A+K VARL G+P E R+KVWL+LA++++ DW++ ++F FNERSNPDDDS+G+QIVKDLHRTGC ++ + Sbjct: 43 SLDSSTETSGSDA---FLGGRGAGDSRVLQELRERPSLRLQMQYLQRKDSSELKTVLRELKYRIGIQSAKLLRQLKQKDRLLHKVQKNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQ 240
BLAST of TBC1 domain family member 2B vs. Ensembl Mouse
Match: Tbc1d2 (TBC1 domain family, member 2 [Source:MGI Symbol;Acc:MGI:2652885]) HSP 1 Score: 124.02 bits (310), Expect = 2.691e-28 Identity = 87/288 (30.21%), Postives = 141/288 (48.96%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNE---RSNPDDDSLGLQIVKDLHRTGCD----TFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYN-MAPMPFPGLSNLR 1498 G+P E R +VW L + + + + E R + QI DL+RT T T S L+RVLLA++ N +GYCQG N LAAI L V+E +EE + +V +V+ ILP Y+++ L A +D V ++ L+ +P+L AH + + + ++ T WFL +FA L D++L +WD+ + EG++++FR LAI++ + +L++ D+ Y +R T + D L++ +N M P P L LR Sbjct: 619 GVPREHRPRVWRWLVHRRVR------HLQAPGCYQELLARGRACEHPAARQIELDLNRTFPTNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLE-DEESAFWCLVAIVETILPAEYYSKTLTASQVDQRVLQDLLSEKLPRLTAH---------------LGQHRVD---LSLITFNWFLVVFADSLISDILLRVWDAFLYEGTKVVFRYALAIFKYNEEAILQLQDSLEIYQYLRFFTKTICDS-----RKLMSIAFNDMNPFPMKQLRQLR 876
BLAST of TBC1 domain family member 2B vs. Ensembl Mouse
Match: Tbc1d2b (TBC1 domain family, member 2B [Source:MGI Symbol;Acc:MGI:1914266]) HSP 1 Score: 105.531 bits (262), Expect = 1.639e-22 Identity = 82/294 (27.89%), Postives = 139/294 (47.28%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQK----YDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDG--LIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNIN 1522 G+P E R KVW + H K D+ + + E+ NP + L +++ L + T L+ VLLA++ N +GYCQG N L A+ L + ++ED+ +V +V+ +P Y+ + L +D VFR+ L+ +P+L H Y+ T + T WFL +F + D++ IWDS + EG ++IFR LA+++ +++LK+ D+ S + +R T + D LI+ +N PFP L +R+R Y++ Sbjct: 664 GIPHEHRSKVWKWCVDRHTRKFKDSMEPDYFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSSPTSEGIQKLRSVLLAFSWRNPDIGYCQGLNRLVAVALLYL--DQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLLSEKLPRLHTHF-----------------EQYKVDYT-LITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEILKLQDSMSIFKYLRYFTRTILDARKLISISFGDLN--------PFP-LRQIRNRRAYHLE 928
BLAST of TBC1 domain family member 2B vs. Ensembl Mouse
Match: Sgsm3 (small G protein signaling modulator 3 [Source:MGI Symbol;Acc:MGI:1916329]) HSP 1 Score: 102.834 bits (255), Expect = 8.471e-22 Identity = 77/277 (27.80%), Postives = 136/277 (49.10%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRT----GCDTFATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDG--LIAQPDHLINRIYNMA 1465 G+P +R ++W+ L+ +QK + + + S+ D+ QI KDL RT C FA + + L+RVL A A +GYCQG ++AA +L +E EED+ +M +++ +LP SYF+ L + D V R + ++P+L + + E ++ T+ WFLT FA+ + L+L IWD EGS ++F+T L + L ++L++ ++ S + T+ + Q+ D L+ + L + ++A Sbjct: 114 GIPHGMRPQLWMRLSG---ALQKKKNSELSYREIIKNSSNDETIAAKQIEKDLLRTMPSNAC--FANVNSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLE--EEDAFWMMCAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLD---------------KLLQEHDIE---LSLITLHWFLTAFASVVHIRLLLRIWDLFFYEGSLVLFQTTLGMLRLKEEELIQSENSASIFNTLSDIPAQMDDAELLLGEAMRLAGSLTDVA 365
BLAST of TBC1 domain family member 2B vs. UniProt/SwissProt
Match: sp|Q28C33|TBC30_XENTR (TBC1 domain family member 30 OS=Xenopus tropicalis OX=8364 GN=tbc1d30 PE=2 SV=1) HSP 1 Score: 498.819 bits (1283), Expect = 3.464e-160 Identity = 260/577 (45.06%), Postives = 368/577 (63.78%), Query Frame = 2 Query: 155 KHECKNSGESVIDNLLFEIYDKW-----AYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGG----MMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQY 1849 + + ++ S+++ LL E+YD + Y R S DS T S SDA + S G SE + + + L QK EL+ +K + + +AI S++L+RQ+K++D K+QKNCDI+TA LQA S KRR DTKLKF +EP G F+QW +A+K VARLP G+P E RK+VWL+LA++++ DW++ ++F FN+RSNPDDDS+G+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK +GYCQGFN+LAA+ILEVME NE D+LK+M+YL+D +LP+SYFA NL+ALS+DMAVFR+ + + +P+L+ H L Q+ A+ + YEPPLTNVFTMQWFLTLFATCLP VL IWDS+ EGSEI+ R LAIW L +Q+ ++D FY TM LT ++ + + + L+ +Y+MA PFP L+ LR+++TYNI PF P+ + S G + D+DE+ + VN ++GC G + P + K+ + SL + +I+++ PGA+ + S +H ERM TD+ L+ QY Sbjct: 74 QQQGRSRTSSLVNGLLTELYDTYRGGAGCYYFRQQDSVDSSTEASGSDAFLSRSNPES-GFLQELSERQSSRHQML---YLKQKDCSELKAIKDELNRRIAIQSAKLLRQVKQKDRLQHKVQKNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWYDALKAVARLPTGIPKEWRKRVWLTLADHYLHSISIDWDKTMRFTFNDRSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTIGYCQGFNILAALILEVMEGNEGDALKVMIYLIDKVLPDSYFANNLRALSVDMAVFRDLVRMKLPELSQH-----LDVLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEILLRVSLAIWAKLGEQIECCQNSDDFYSTMGRLTQEMLEDSLIDSNELMQTVYSMAQFPFPQLAELREKYTYNITPF---PAPVKSASFSGRTSKMRDSDEENEIDEDDVNANAVGCLGPFSGFLAPELQKYQKQIKDQKEEQSLKASNIAELSPGAIDSCRSEYHAVFNSMMMERMTTDINALKQQY 638
BLAST of TBC1 domain family member 2B vs. UniProt/SwissProt
Match: sp|Q9Y2I9|TBC30_HUMAN (TBC1 domain family member 30 OS=Homo sapiens OX=9606 GN=TBC1D30 PE=1 SV=2) HSP 1 Score: 486.878 bits (1252), Expect = 2.739e-155 Identity = 260/541 (48.06%), Postives = 346/541 (63.96%), Query Frame = 2 Query: 248 SWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGG----MMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQY 1849 S DS T S SD V G R G S E + + L QK EL+ + +K + I S++L+R LK++D L K+Q+NCDI+TA LQA S KRR DTKLKF +EP G F+QW +A+K VARL G+P E R+KVWL+LA++++ DW++ ++F FNERSNPDDDS+G+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK VGYCQGFN+LAA+ILEVME NE D+LKIM+YL+D +LPESYF NL+ALS+DMAVFR+ L + +P+L+ H L + Q+ A+ + YEPPLTNVFTMQWFLTLFATCLP VL IWDS+ EGSEII R LAIW L +Q+ AD FY TM LT ++ + + Q L+ +Y+MAP PFP L+ LR+++TYNI PF P+ + G + D+DE+ D + ++GC G + P + KE SL S +I+++ PGA+++ S +H A ERM TD+ L+ QY Sbjct: 114 SLDSSTEASGSDVVLG--GRSGAGDSRVLQELQERPSQRHQMLYLRQKDANELKTILRELKYRIGIQSAKLLRHLKQKDRLLHKVQRNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQH-----LDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLAELREKYTYNITPF---PATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAPELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQY 644
BLAST of TBC1 domain family member 2B vs. UniProt/SwissProt
Match: sp|Q69ZT9|TBC30_MOUSE (TBC1 domain family member 30 OS=Mus musculus OX=10090 GN=Tbc1d30 PE=1 SV=2) HSP 1 Score: 431.795 bits (1109), Expect = 3.315e-136 Identity = 222/456 (48.68%), Postives = 302/456 (66.23%), Query Frame = 2 Query: 503 QKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGM--MPSNHLSNYKA--KENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQY 1849 +++C TA +L+ DTKLKF +EP G F+QW +A+K VARL G+P E R+KVWL+LA++++ DW++ ++F FNERSNPDDDS+G+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK VGYCQGFN+LAA+ILEVME NE D+LKIM+YL+D +LPESYF NL+ALS+DMAVFR+ L + +P+L+ HL+ LQ A+ + YEPPLTNVFTMQWFLTLFATCLP VL IWDS+ EGSEII R LAIW L +Q+ AD FY TM LT ++ + + Q L+ +Y+MAP PFP L+ LR+++TYNI PF P+ I G + D+D++ + +++GC G + + + L Y+ KE +L S +I+++ PGA+++ S +H A ERM TD+ L+ QY Sbjct: 35 KRSCISRTAPRLLCTLEPGVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKNVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRLKLPELSQHLDTLQRT-----ANKESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYGTMGRLTQEMLEQDLLQSHELMQTVYSMAPFPFPQLAELREKYTYNITPF---PATIKPTSVSGRHSKARDSDDENGPDDEDAVASAVGCLGPLSGLLAPELQKYQKQIKEATEEQTLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQY 482
BLAST of TBC1 domain family member 2B vs. UniProt/SwissProt
Match: sp|B5DFA1|TBD2A_RAT (TBC1 domain family member 2A OS=Rattus norvegicus OX=10116 GN=Tbc1d2 PE=2 SV=1) HSP 1 Score: 128.257 bits (321), Expect = 1.081e-28 Identity = 90/285 (31.58%), Postives = 140/285 (49.12%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCD----TFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYN-MAPMPFPGLSNLR 1498 G+P E R +VW L H VQ + + R + QI DL+RT T T S L+RVLLA++ N +GYCQG N LAAI L V+E +EE + +V +V+ ILP Y+++ L A +D V ++ L+ +P+L AH + H + ++ T WFL +FA L D++L +WD+ + EG++++FR LAI++ + +L++ D+ Y +R T + D L + +N M P P L LR Sbjct: 621 GVPREHRPRVWRWLV--HRRVQHLHSSGCYQELLA-RGRACEHPAARQIELDLNRTFPTNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLE-DEESAFWCLVAIVETILPAEYYSKTLTASQVDQRVLQDLLSEKLPRLTAH---------------LGQRHVD---LSLITFNWFLVIFADSLISDILLRVWDAFLYEGTKVVFRYALAIFKYNEEAILRLQDSLEIYQYLRFFTKTICDS-----RKLTSIAFNDMNPFPMKQLRQLR 878
BLAST of TBC1 domain family member 2B vs. UniProt/SwissProt
Match: sp|B1AVH7|TBD2A_MOUSE (TBC1 domain family member 2A OS=Mus musculus OX=10090 GN=Tbc1d2 PE=2 SV=1) HSP 1 Score: 124.02 bits (310), Expect = 1.882e-27 Identity = 87/288 (30.21%), Postives = 141/288 (48.96%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNE---RSNPDDDSLGLQIVKDLHRTGCD----TFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYN-MAPMPFPGLSNLR 1498 G+P E R +VW L + + + + E R + QI DL+RT T T S L+RVLLA++ N +GYCQG N LAAI L V+E +EE + +V +V+ ILP Y+++ L A +D V ++ L+ +P+L AH + + + ++ T WFL +FA L D++L +WD+ + EG++++FR LAI++ + +L++ D+ Y +R T + D L++ +N M P P L LR Sbjct: 619 GVPREHRPRVWRWLVHRRVR------HLQAPGCYQELLARGRACEHPAARQIELDLNRTFPTNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLE-DEESAFWCLVAIVETILPAEYYSKTLTASQVDQRVLQDLLSEKLPRLTAH---------------LGQHRVD---LSLITFNWFLVVFADSLISDILLRVWDAFLYEGTKVVFRYALAIFKYNEEAILQLQDSLEIYQYLRFFTKTICDS-----RKLMSIAFNDMNPFPMKQLRQLR 876
BLAST of TBC1 domain family member 2B vs. TrEMBL
Match: A0A1S3HFQ2 (TBC1 domain family member 30-like isoform X2 OS=Lingula unguis OX=7574 GN=LOC106154903 PE=4 SV=1) HSP 1 Score: 548.125 bits (1411), Expect = 9.631e-174 Identity = 286/585 (48.89%), Postives = 382/585 (65.30%), Query Frame = 2 Query: 125 PDSHSESLFEKHECKNSGESVIDNLLFEIYDKWAYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLS---SVDISQVGPGAVSTSPSIHHNAS----PGATQERMCTDLITLESQY 1849 PD H S F K S++D+LLFEIYD+W H S+DSDT T AS F R + E E +H ++++ L K EL ++ +K +VA ++RLVRQL++RDH AK+QKNCD++TA+LQA+SLKRR D+++KF ++P PG++A++QW +AMK V RLP+G+P E R+KVWLSLA+NHI DW + +K FNE+SNPDD+ LGLQIVKDLHRTGC F+ E +RA+LKRVLLAYARWNK VGYCQGFNV+AA+IL VMER E D+LK+M+YL+DH+LP SYFA NL++LS+DMAVFR+ L + +P L+ HL+ LQ ++ C N YEPPLTNVFTMQWFLTLFATCLP VL +WDS++LEGSE++ RTGL IW L+ +++ V AD FY M LT+++ D + PD LI +IY MAP P P L+ LR+++ +NI PF A ++ G G T +D + + + +I CF L N + ++ L ++ + DIS VGPGA +P NAS A ERM TDL L+ QY Sbjct: 87 PDDHDIS-FSKRCSFMRQASIVDDLLFEIYDRW--HVTHRDSFDSDTFTEASSTSEVFHSGRYGSYQL---ELEQRHSNKLNKAFLQNKEEAELRRMVHELKHTVAQMNTRLVRQLRKRDHMKAKLQKNCDVVTAVLQAASLKRRVDSRIKFSLQPLPGDDAYQQWLDAMKAVVRLPMGIPKEFRRKVWLSLADNHIKNLSVDWEKTLKVTFNEKSNPDDNKLGLQIVKDLHRTGCSGFSGQDNEQDRAVLKRVLLAYARWNKTVGYCQGFNVIAALILNVMERKEGDTLKVMIYLIDHVLPTSYFANNLRSLSVDMAVFRDLLRMKLPGLSRHLDYLQAAAK----DCTGAN-YEPPLTNVFTMQWFLTLFATCLPKTTVLRVWDSVLLEGSEVLLRTGLGIWAKLAKRIMTVQSADEFYQMMASLTSEMLDTDLIDPDSLIKKIYAMAPFPLPRLTELREKYEFNITPF----QAAMNAGRLGAKTRSSAHIFSDDDEIEEEDFENINCFSAF----GLFNPQGSPSKGDLGVTPSLTFDISSVGPGAFGANP---ENASMQVKNTAYTERMTTDLGALQKQY 649
BLAST of TBC1 domain family member 2B vs. TrEMBL
Match: A0A1S3HFS5 (TBC1 domain family member 30-like isoform X1 OS=Lingula unguis OX=7574 GN=LOC106154903 PE=4 SV=1) HSP 1 Score: 546.199 bits (1406), Expect = 4.470e-173 Identity = 285/585 (48.72%), Postives = 382/585 (65.30%), Query Frame = 2 Query: 125 PDSHSESLFEKHECKNSGESVIDNLLFEIYDKWAYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLS---SVDISQVGPGAVSTSPSIHHNAS----PGATQERMCTDLITLESQY 1849 PD H S F K S++D+LLFEIYD+W H S+DSDT T AS R + E E +H + ++++ L K EL ++ +K +VA ++RLVRQL++RDH AK+QKNCD++TA+LQA+SLKRR D+++KF ++P PG++A++QW +AMK V RLP+G+P E R+KVWLSLA+NHI DW + +K FNE+SNPDD+ LGLQIVKDLHRTGC F+ E +RA+LKRVLLAYARWNK VGYCQGFNV+AA+IL VMER E D+LK+M+YL+DH+LP SYFA NL++LS+DMAVFR+ L + +P L+ HL+ LQ ++ C N YEPPLTNVFTMQWFLTLFATCLP VL +WDS++LEGSE++ RTGL IW L+ +++ V AD FY M LT+++ D + PD LI +IY MAP P P L+ LR+++ +NI PF A ++ G G T +D + + + +I CF L N + ++ L ++ + DIS VGPGA +P NAS A ERM TDL L+ QY Sbjct: 87 PDDHDIS-FSKRCSFMRQASIVDDLLFEIYDRW--HVTHRDSFDSDTFTEASSTSEVLHSGRYGSYQL---ELEQRHSSKLNKAFLQNKEEAELRRMVHELKHTVAQMNTRLVRQLRKRDHMKAKLQKNCDVVTAVLQAASLKRRVDSRIKFSLQPLPGDDAYQQWLDAMKAVVRLPMGIPKEFRRKVWLSLADNHIKNLSVDWEKTLKVTFNEKSNPDDNKLGLQIVKDLHRTGCSGFSGQDNEQDRAVLKRVLLAYARWNKTVGYCQGFNVIAALILNVMERKEGDTLKVMIYLIDHVLPTSYFANNLRSLSVDMAVFRDLLRMKLPGLSRHLDYLQAAAK----DCTGAN-YEPPLTNVFTMQWFLTLFATCLPKTTVLRVWDSVLLEGSEVLLRTGLGIWAKLAKRIMTVQSADEFYQMMASLTSEMLDTDLIDPDSLIKKIYAMAPFPLPRLTELREKYEFNITPF----QAAMNAGRLGAKTRSSAHIFSDDDEIEEEDFENINCFSAF----GLFNPQGSPSKGDLGVTPSLTFDISSVGPGAFGANP---ENASMQVKNTAYTERMTTDLGALQKQY 649
BLAST of TBC1 domain family member 2B vs. TrEMBL
Match: C3YVF5 (Rab-GAP TBC domain-containing protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_70346 PE=4 SV=1) HSP 1 Score: 541.191 bits (1393), Expect = 7.339e-173 Identity = 295/624 (47.28%), Postives = 392/624 (62.82%), Query Frame = 2 Query: 182 SVIDNLLFEIYDKWAYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELK----HYTT-ISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYXXXXXXXXXTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTA-SHIIVSSTYPSLQN 2035 S+ID LL E+YD+ Y DS DSDT T S + + SE EL+ YT+ + + L +K ++EL ++ + + + S +LVRQLKRRD +K+QKNCDILTAILQA S KRR DT++KF +EP PG + FRQW +AMK V RLP GLPSE RK+VWL LA+ HI + DW+++ + AFNERSNPDDD LG+QIVKDLHRTGC F E +R +LKRVLLAYARWNK VGYCQGFNVLAA+ILEV+ER EED+LK+M+YL+D++LP+S+FA NL+ALS+DMAVFRE L I +P L+ H L Q+ A+ +YEPPLTNVF MQWFLTLFATCLP VL +WDS+ EGSEI+ RT LAIW L D+L ++ AD FY TM L ++ + P+ L+ +Y++AP PFPGL LR+++TYNI PFS + + ++E + +IGCFGG+ P S K + Q P+S D+ +V PGA S S + H + A ERM TD+ L+ QY +I+ KQ++T L+ G+E S+ + S+ R P A +H+ V+ S+Q Sbjct: 82 SLIDGLLCELYDRVPYGLGRDS-LDSDTYTEYSSTSE-------VHCAGTRSEQELEPSHLTYTSRVQSACLREKEVKELRQMVEELSRRTNMISQKLVRQLKRRDRRKSKLQKNCDILTAILQAVSEKRRIDTRMKFSIEPMPGKKGFRQWFDAMKAVVRLPHGLPSEWRKRVWLCLADKHIQNLQLDWDKMCRLAFNERSNPDDDKLGVQIVKDLHRTGCSGFCAEQDRVVLKRVLLAYARWNKSVGYCQGFNVLAALILEVVERVEEDALKVMIYLIDYVLPDSFFANNLRALSVDMAVFRELLRIRLPDLSKH-----LDDLQKRANSNPQGNYEPPLTNVFVMQWFLTLFATCLPKSTVLRVWDSVFFEGSEILLRTALAIWAKLGDRLRDLDSADQFYGTMAMLCQEMLMMNLIDPNELVQTVYSLAPFPFPGLDELREKYTYNITPFSPLGTDKAK-----KAMKMATNSDEEVELDEDDLAMAIGCFGGIFPP-ETSPKKKEGEQKPVS----DMREVSPGAYS-SRTEHIEMTRTALMERMSTDITALKKQYMRIRQKQQRTHLIYPKQGNENKSTSTHKF---------SATARDTPIAMNHLYVARKIASIQG 672
BLAST of TBC1 domain family member 2B vs. TrEMBL
Match: A0A0L8ICM3 (Rab-GAP TBC domain-containing protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22018454mg PE=4 SV=1) HSP 1 Score: 514.227 bits (1323), Expect = 1.408e-164 Identity = 285/600 (47.50%), Postives = 387/600 (64.50%), Query Frame = 2 Query: 182 SVIDNLLFEIYDKWAYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPK-PGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHL-SNYKAKENQMPLSLSS----VDISQVGPGAVSTSPSIHHNAS---PGATQERMCTDLITLESQYXXXXXXXXXTSLLMNNIGHEKISSKSQVLAPS 1945 S+ D+LLFEIYD+W Y DS +DSDT T S A + S E E + S + L + +E+L++++ +++ + S+RLVRQLKRRDH +AK+ N D++TA LQASSLKRR DT++KF +EP G A+ QW +AMKGVARLPLG+P E R+KVWLSLA+++I DW + ++FAFN+R NPDD+ LGLQIVKDLHRTGC +F+ E ERA+LKRVLLAYARWNK VGYCQGFNV+AA++L+V +R E+++LK+MVYL+DH+LP+SYFA NL+ALS+DMAVFR+ L+ P L+ HL NLQ +Q++ + I YEPPLTNVFTMQWFLTLFATCLP VL +WDSI+LEGSEI+ R L IW LS ++L V AD FY M LT ++ G P+ LI IY+++P PFP LS LR+++TYNI PFS ++ G N +D + +A I CF G+ L S KAK + +S ++ DIS VGPG N + A ERM TDL L+ QY++++ +Q + ++++ + S + + P+ Sbjct: 177 SIFDDLLFEIYDQW-YDSYRDS-FDSDTFTEYSSAAE-IPHYYTTARSEYHLEIEDRRIKKFSRAYLENQGLEKLKEIESSLRYDINQMSARLVRQLKRRDHRIAKLSCNFDLVTAFLQASSLKRRIDTRIKFSIEPPLVGENAYEQWVDAMKGVARLPLGIPEEFRRKVWLSLADHYIKEIHLDWEKTVRFAFNDRCNPDDNKLGLQIVKDLHRTGCRSFSGHDNEEERAVLKRVLLAYARWNKNVGYCQGFNVIAALLLDVFDRREDEALKVMVYLIDHVLPDSYFANNLRALSVDMAVFRDLLHWKFPYLSQHLENLQKAAQEEASGAI----YEPPLTNVFTMQWFLTLFATCLPKKTVLRLWDSILLEGSEILLRAALVIWNKLSKRILMVGSADEFYTLMGELTQEMVSGDKFSPEKLIKAIYSISPFPFPQLSELREKYTYNIRPFSGTANS----GKKVNQFDGGGVSISDDDLDEEDMEA-IRCFTGLFNLQSLNSANKAKGLEGDVSSTANTNCNDISMVGPGIYGMPSVTDSNLTVNRSSAYMERMTTDLCALKKQYQRLRQRQAQAHIILSAANTYQQKSHTDFITPT 764
BLAST of TBC1 domain family member 2B vs. TrEMBL
Match: A0A0L8ICT6 (Rab-GAP TBC domain-containing protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22018454mg PE=4 SV=1) HSP 1 Score: 509.22 bits (1310), Expect = 1.585e-162 Identity = 285/610 (46.72%), Postives = 388/610 (63.61%), Query Frame = 2 Query: 182 SVIDNLLFEIYDKWAYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPK-PGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCI----------NNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHL-SNYKAKENQMPLSLSS----VDISQVGPGAVSTSPSIHHNAS---PGATQERMCTDLITLESQYXXXXXXXXXTSLLMNNIGHEKISSKSQVLAPS 1945 S+ D+LLFEIYD+W Y DS +DSDT T S A + S E E + S + L + +E+L++++ +++ + S+RLVRQLKRRDH +AK+ N D++TA LQASSLKRR DT++KF +EP G A+ QW +AMKGVARLPLG+P E R+KVWLSLA+++I DW + ++FAFN+R NPDD+ LGLQIVKDLHRTGC +F+ E ERA+LKRVLLAYARWNK VGYCQGFNV+AA++L+V +R E+++LK+MVYL+DH+LP+SYFA NL+ALS+DMAVFR+ L+ P L+ HL NLQ +Q++ + I + YEPPLTNVFTMQWFLTLFATCLP VL +WDSI+LEGSEI+ R L IW LS ++L V AD FY M LT ++ G P+ LI IY+++P PFP LS LR+++TYNI PFS ++ G N +D + +A I CF G+ L S KAK + +S ++ DIS VGPG N + A ERM TDL L+ QY++++ +Q + ++++ + S + + P+ Sbjct: 177 SIFDDLLFEIYDQW-YDSYRDS-FDSDTFTEYSSAAE-IPHYYTTARSEYHLEIEDRRIKKFSRAYLENQGLEKLKEIESSLRYDINQMSARLVRQLKRRDHRIAKLSCNFDLVTAFLQASSLKRRIDTRIKFSIEPPLVGENAYEQWVDAMKGVARLPLGIPEEFRRKVWLSLADHYIKEIHLDWEKTVRFAFNDRCNPDDNKLGLQIVKDLHRTGCRSFSGHDNEEERAVLKRVLLAYARWNKNVGYCQGFNVIAALLLDVFDRREDEALKVMVYLIDHVLPDSYFANNLRALSVDMAVFRDLLHWKFPYLSQHLENLQKAAQEEASGLIKYIPFIPQFESGAIYEPPLTNVFTMQWFLTLFATCLPKKTVLRLWDSILLEGSEILLRAALVIWNKLSKRILMVGSADEFYTLMGELTQEMVSGDKFSPEKLIKAIYSISPFPFPQLSELREKYTYNIRPFSGTANS----GKKVNQFDGGGVSISDDDLDEEDMEA-IRCFTGLFNLQSLNSANKAKGLEGDVSSTANTNCNDISMVGPGIYGMPSVTDSNLTVNRSSAYMERMTTDLCALKKQYQRLRQRQAQAHIILSAANTYQQKSHTDFITPT 778
BLAST of TBC1 domain family member 2B vs. Ensembl Cavefish
Match: tbc1d30 (TBC1 domain family member 30 [Source:NCBI gene;Acc:103024461]) HSP 1 Score: 425.631 bits (1093), Expect = 9.204e-134 Identity = 233/506 (46.05%), Postives = 324/506 (64.03%), Query Frame = 2 Query: 563 DTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHLSNYKA--KENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYXXXXXXXXXTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTASHIIVSSTYPSLQNSMVNHLFLTR 2065 DT+LKF +EP G F+QW +A+K VARLP G+P E R+KVWL+LA+ ++ DW + ++FAFNERSNPDDDSLG+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK VGYCQGFNVLAA+ILEV E NE D+LK+M+YL+D +LP+SYFA NL+ALS+DMAVFR+ L I +P+L+ HL++LQ A+ YEPPLTNVFTMQWFLT+FATCLP VL IWDS+ EGSE++ R LAIW L +++ + AD FY TM LT ++ + + + L+ +Y+MA PFP L+ LR+++TYNI PF P+ + + GS G E D D D D + V G + + + Y+ KE + L+ SS +++++ PGAV + H ERM TD+ L QY +IK +Q++ + L+ H + +++ +AP + + S+ P A+ ++ S + S +VNHL L R Sbjct: 56 DTRLKFTLEPSLGKNGFQQWYDALKSVARLPTGIPKEWRRKVWLTLADQYLHSISIDWEKTMRFAFNERSNPDDDSLGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNVLAALILEVTEGNEGDALKVMIYLIDKVLPDSYFANNLRALSVDMAVFRDLLRIKLPELSQHLHHLQKV-----ANRTGGGSYEPPLTNVFTMQWFLTMFATCLPHHTVLKIWDSVFFEGSEVLLRVALAIWAKLGERIEECQTADEFYSTMGILTQEMLEQNLIDSNELMQTVYSMADFPFPQLAELREKYTYNITPF---PAPVKANGSQGIHGWESDDDGDMDDEDSIVTALGCLGPLGGLLAPEIQRYQKHLKEQRGELTSSSSNMAELSPGAVGGGRAEHQATMNSMMLERMSTDIRALTKQYSRIKRRQQQQAGLL--YIHTGLPVETEPVAPHQPSEWASNDSGKCP-ATSVMASQVHTS---PVVNHLLLGR 547
BLAST of TBC1 domain family member 2B vs. Ensembl Cavefish
Match: tbc1d30 (TBC1 domain family member 30 [Source:NCBI gene;Acc:103024461]) HSP 1 Score: 422.55 bits (1085), Expect = 5.927e-133 Identity = 215/434 (49.54%), Postives = 287/434 (66.13%), Query Frame = 2 Query: 563 DTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHLSNYKA--KENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQY 1849 DT+LKF +EP G F+QW +A+K VARLP G+P E R+KVWL+LA+ ++ DW + ++FAFNERSNPDDDSLG+QIVKDLHRTGC ++ E +R +LKRVLLAYARWNK VGYCQGFNVLAA+ILEV E NE D+LK+M+YL+D +LP+SYFA NL+ALS+DMAVFR+ L I +P+L+ HL++LQ A+ YEPPLTNVFTMQWFLT+FATCLP VL IWDS+ EGSE++ R LAIW L +++ + AD FY TM LT ++ + + + L+ +Y+MA PFP L+ LR+++TYNI PF P+ + + GS G E D D D D + V G + + + Y+ KE + L+ SS +++++ PGAV + H ERM TD+ L QY Sbjct: 56 DTRLKFTLEPSLGKNGFQQWYDALKSVARLPTGIPKEWRRKVWLTLADQYLHSISIDWEKTMRFAFNERSNPDDDSLGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNVLAALILEVTEGNEGDALKVMIYLIDKVLPDSYFANNLRALSVDMAVFRDLLRIKLPELSQHLHHLQKV-----ANRTGGGSYEPPLTNVFTMQWFLTMFATCLPHHTVLKIWDSVFFEGSEVLLRVALAIWAKLGERIEECQTADEFYSTMGILTQEMLEQNLIDSNELMQTVYSMADFPFPQLAELREKYTYNITPF---PAPVKANGSQGIHGWESDDDGDMDDEDSIVTALGCLGPLGGLLAPEIQRYQKHLKEQRGELTSSSSNMAELSPGAVGGGRAEHQATMNSMMLERMSTDIRALTKQY 481
BLAST of TBC1 domain family member 2B vs. Ensembl Cavefish
Match: tbc1d2 (TBC1 domain family, member 2 [Source:ZFIN;Acc:ZDB-GENE-140106-100]) HSP 1 Score: 122.865 bits (307), Expect = 4.167e-28 Identity = 87/267 (32.58%), Postives = 137/267 (51.31%), Query Frame = 2 Query: 632 MKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKF--AFNERSNPDDDSLGLQIVKDLHRTGCDT--FATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSD 1414 +KG+ R G+P E R++VW + T K D R E+S QI DLHRT F++ S A+ L RVLLA+A N VGYCQG N LAA+ L V++ NEED+ +V +V ++P+ Y+ + L D VF++F+ +P+L AHL + ++ T WFL +F LP +++L +WD+ EG+++IFR LA+++ + +LK++D+ Y +R T ++D Sbjct: 504 LKGLLRW--GIPREYRRRVWSWMVR---TRTKSDRERHPDLFQQLCEKSLTTPHPASRQIQLDLHRTLTTNQHFSSPSSPALQQLHRVLLAFAWQNPEVGYCQGLNRLAALALLVLQ-NEEDAFWCLVTIVQSLMPQDYYTKTLLGSQADQRVFKDFMAEKLPRLVAHLEEHNVD------------------VSLITFNWFLVVFVESLPSEILLKVWDAFFYEGTKVIFRYALALFKYKEEDILKIHDSTEIYQYLRFFTKTVTD 746
BLAST of TBC1 domain family member 2B vs. Ensembl Cavefish
Match: tbc1d2 (TBC1 domain family, member 2 [Source:ZFIN;Acc:ZDB-GENE-140106-100]) HSP 1 Score: 116.701 bits (291), Expect = 2.904e-26 Identity = 88/296 (29.73%), Postives = 143/296 (48.31%), Query Frame = 2 Query: 632 MKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKF--AFNERSNPDDDSLGLQIVKDLHRTGCDT--FATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGS-EIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLR 1498 +KG+ R G+P E R++VW + T K D R E+S QI DLHRT F++ S A+ L RVLLA+A N VGYCQG N+ A + ++ +NEED+ +V +V ++P+ Y+ + L D VF++F+ +P+L AHL + ++ T WFL +F LP +++L +WD+ EG+ ++IFR LA+++ + +LK++D+ Y +R T ++D + + + P P L N R Sbjct: 473 LKGLLRW--GIPREYRRRVWSWMVR---TRTKSDRERHPDLFQQLCEKSLTTPHPASRQIQLDLHRTLTTNQHFSSPSSPALQQLHRVLLAFAWQNPEVGYCQGLNLAALAL--LVLQNEEDAFWCLVTIVQSLMPQDYYTKTLLGSQADQRVFKDFMAEKLPRLVAHLEEHNVD------------------VSLITFNWFLVVFVESLPSEILLKVWDAFFYEGTKQVIFRYALALFKYKEEDILKIHDSTEIYQYLRFFTKTVTDSKL-----MTIAFTELNPFPMKLLRNRR 738
BLAST of TBC1 domain family member 2B vs. Ensembl Cavefish
Match: sgsm3 (small G protein signaling modulator 3 [Source:NCBI gene;Acc:103030541]) HSP 1 Score: 107.457 bits (267), Expect = 2.466e-23 Identity = 72/257 (28.02%), Postives = 128/257 (49.81%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRT----GCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDG 1417 G+P +R ++W+ L+ +QK + + + S+ DD + QI KDL RT C + T LKRVL A +GYCQG ++ + +L +E EED+L +M L++ +LP SYF+ L + D V R+ + ++P L + + E ++ ++ WFLT FA+ + ++L IWD + +GS ++F+ L + ++ ++L+ ++ S + T+ L +QL DG Sbjct: 115 GIPHSMRPQLWMRLSG---ALQKKRTSEISYREIIKNSSNDDTTAAKQIEKDLLRTMPTNACFSTLTSVGVPRLKRVLRGLAWLYPDIGYCQGTGMVVSCLLLFLE--EEDALWMMCALIEDLLPPSYFSSTLLGVQTDQRVLRQLIVQYLPSLD---------------QLLQEHDIE---LSLISLHWFLTSFASVVDIRILLRIWDLLFYDGSIVLFQVTLGMLKIKEEELVSSENSASIFNTLSDLPSQLEDG 348
BLAST of TBC1 domain family member 2B vs. Ensembl Sea Lamprey
Match: tbc1d2b (TBC1 domain family, member 2B [Source:ZFIN;Acc:ZDB-GENE-100922-148]) HSP 1 Score: 132.494 bits (332), Expect = 1.041e-31 Identity = 81/256 (31.64%), Postives = 128/256 (50.00%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDT--FATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSD 1414 G+P E+R +VW H+ + ERS+ + Q+ DL RT + F T+S I L+RVLLAYA N VGYCQG N LAAI L +E EE + +V +V+ ++P Y+++ L A +D +F+E + +P+LAAH + ++ T WFL LF + D+V IWD+ + EG+++IFR LA+ + +QL+K + + + +R T+ + D Sbjct: 655 GVPHELRSRVWRWAVEQHVRAIRGRHAASYYCELLERSHGQHNPAARQVELDLPRTLPNNRHFETQSSEGIVKLRRVLLAYAWHNPEVGYCQGLNRLAAIALIYLE--EEQAFWCLVAIVECLMPPDYYSKTLLASQVDQRLFKELVTEKLPRLAAHFEQHGVD------------------VSLITFNWFLVLFVDSVGSDMVFRIWDAFLYEGTKVIFRYALAMLKCREEQLIKHHSNSAIFNYLRIFTHSIHD 890
BLAST of TBC1 domain family member 2B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006389.1 (pep scaffold:Pmarinus_7.0:GL481951:143257:161898:-1 gene:ENSPMAG00000005741.1 transcript:ENSPMAT00000006389.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 97.0561 bits (240), Expect = 1.170e-20 Identity = 65/239 (27.20%), Postives = 117/239 (48.95%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYD--WNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVND 1363 G+P +R ++W+ + + Y + +++ + S D+ I +DLHR+ + A +SE I L+RVL AYA N +GYCQ N++ +++L + EE++ ++V L + +LP+ Y + + AL +D VF E H+P+L + + + + ++ WFLTLF + LP + + D ML+G +IF+ LA+ +LL +D Sbjct: 432 GIPESLRGELWMHFSGAIHEMNSYPGYYAEIVRSSMGRMSLVTDE-----IERDLHRSLPEHPAFQSEMGIAALRRVLTAYAHRNPSIGYCQAMNIVTSVLL--LYTKEEEAFWLLVALCERMLPDYYNTRVVVAL-VDQGVFEELTREHLPQLCERMQ-------------------DLGVISTISLSWFLTLFLSVLPFSSAVCVVDCFMLDGVRMIFQLALAVLHANMGKLLSCHD 643
BLAST of TBC1 domain family member 2B vs. Ensembl Sea Lamprey
Match: TBC1D9 (TBC1 domain family member 9 [Source:HGNC Symbol;Acc:HGNC:21710]) HSP 1 Score: 87.8113 bits (216), Expect = 6.988e-18 Identity = 66/237 (27.85%), Postives = 111/237 (46.84%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVND 1363 G+P +R+++WL + V N +RS +I +DLHR+ + A + I L+RVL AYA N R+GYCQ N++ + +L + +EE++ ++V L + +LP+ Y + + AL ID VF E + +P L + E ++ WFLTLF + LP + + D ML+G+ ++F+ LA+ ++ LL D Sbjct: 443 GIPVRLRRELWLLFSG---AVHDMGSNPGHYAELVDRSLGRASIATEEIERDLHRSLPEHPAFQHPLGIDALRRVLTAYAHRNPRIGYCQAMNIVTSALL--IFASEEEAFWLLVALCERLLPDYYNNRVVGAL-IDQGVFEELIAEFLPTL-------------------HERLQELGFIATTSLSWFLTLFLSVLPLESAACVLDCFMLDGARVLFQLALAVLHANAEPLLACRD 654
BLAST of TBC1 domain family member 2B vs. Ensembl Sea Lamprey
Match: tbc1d10b (TBC1 domain family, member 10b [Source:ZFIN;Acc:ZDB-GENE-030131-7754]) HSP 1 Score: 75.8702 bits (185), Expect = 1.193e-14 Identity = 70/278 (25.18%), Postives = 116/278 (41.73%), Query Frame = 2 Query: 605 EAFRQWCEAM-KGVARLPL----GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIV-KDLHRTGC--DTFATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTN--VFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTN 1402 E R W + + KG ++ L G+P +R + W L+ + +++ + F E D L+++ KDLHR + F + + L RVL AY + GYCQG +AA++L M E++ V + + LP Y++ L++L +D + L S I H + + ++ +WF+ +F+ LP D VL +WD EG + +FR GL + +V Y TM L N Sbjct: 15 EMLRYWDKWITKGYKKVKLRCRKGIPPSLRARAWEHLSGSKYIMEQ------MPGKFEELDKLPGDPKWLEVIQKDLHRQFPFHELFRAKGGQGQQDLFRVLKAYTVYRPEEGYCQGQAPVAAVLL--MHMPAEEAFWCFVQICEKYLP-GYYSAGLESLQLDGEILFALLR--------------------KVSLIGYRHLKWHSVDPVLYMTEWFMCVFSRTLPWDSVLRVWDMFFCEGVKTMFRVGLVLLRHALGNSERVRMCPGLYETMEQLKN 263
BLAST of TBC1 domain family member 2B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010479.1 (pep scaffold:Pmarinus_7.0:GL480469:1915:23479:-1 gene:ENSPMAG00000009488.1 transcript:ENSPMAT00000010479.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 72.7886 bits (177), Expect = 1.572e-13 Identity = 48/159 (30.19%), Postives = 77/159 (48.43%), Query Frame = 2 Query: 875 VLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLL 1351 V+ AY+ ++ VGYCQG + ++L M+ EE++ + + L+ F ++ L + M + + +L AHL+ ++ H T++F WFLT+F T P L I+D M EG E+IFR G+AI L D+LL Sbjct: 45 VMKAYSLVDREVGYCQGSAFIVGLLL--MQMPEEEAFCVFIRLMHDYRLRELFKPSMAELGLCMYQIESLMQDQLSQLHAHLST-------------HSVH-----TSMFASPWFLTVFLTTFPLPLAARIFDWFMCEGLEVIFRVGVAILSALQDELL 183
BLAST of TBC1 domain family member 2B vs. Ensembl Yeast
Match: MDR1 (Cytoplasmic GTPase-activating protein; activates Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function [Source:SGD;Acc:S000003332]) HSP 1 Score: 83.5741 bits (205), Expect = 8.190e-17 Identity = 69/264 (26.14%), Postives = 125/264 (47.35%), Query Frame = 2 Query: 656 LGLPSEIRKKVW--LSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPD 1435 +G+P+ +R ++W S A ++ R++ NE + ++ +I KDL R+ + A ++E I L+ VL AY+ N VGYCQ N++ A L M +EE + + L D +P Y+++ + +D VF F+ +P L ++ ++ L+ V ++ WFL+LF T +P + + I D + GS +F+ LA+ ++ +D +L+ +D F ++ L G A PD Sbjct: 243 IGVPNRMRGEIWELCSGAMYMRYANSGEYERIL----NENAGKTSQAID-EIEKDLKRSLPEYSAYQTEEGIQRLRNVLTAYSWKNPDVGYCQAMNIVVAGFLIFM--SEEQAFWCLCNLCDIYVP-GYYSKTMYGTLLDQRVFESFVEDRMPVLWEYIL-----------------QHDIQLS-VVSLPWFLSLFFTSMPLEYAVRIMDIFFMNGSITLFQVALAVLKINADDILQADDDGMFIAIIKHYFQTL--GQSAHPD 478
BLAST of TBC1 domain family member 2B vs. Ensembl Yeast
Match: MSB4 (GTPase-activating protein of the Ras superfamily; acts primarily on Sec4p, localizes to the bud site and bud tip; msb3 msb4 double mutation causes defects in secretion and actin organization; similar to the TBC-domain Tre2 oncogene; MSB4 has a paralog, MSB3, that arose from the whole genome duplication; human homolog USP6NL can complement yeast msb3 msb4 double null mutant [Source:SGD;Acc:S000005472]) HSP 1 Score: 81.2629 bits (199), Expect = 2.493e-16 Identity = 69/250 (27.60%), Postives = 116/250 (46.40%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNH----ITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDT--FATES----ERAI---LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXX---XXXXXASCINNNHY--EPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLK 1354 G+P+E R W A V YD +K E + D ++ +DL+RT D F ES E AI L+RVL+A++ ++K +GYCQ N L ++L ME EE + ++V + LP Y +L+ ++D V + ++P++ +H+ + + S Q + + Y P + T WF++ F +P + L IWD + E S +F+ L I +L + L+ Sbjct: 147 GIPAEWRGNAWWYFAGGQRQLDANVGVYD---RLKSDCREGAVSGKDMEAIE--RDLYRTFPDNIHFHKESFQNGEPAIIRSLRRVLMAFSVYDKTIGYCQSMNFLVGLLLLFME--EEKAFWMLVIITGKYLPGVY-ESDLEGANVDQGVLVLCIKEYLPEIWSHIESSYMNGNGSTDQISGPASGEEYLCRLPTLTLCTASWFMSCFVGVVPIETTLRIWDCLFYEESHFLFKVALGILKLSESEFLE 388
BLAST of TBC1 domain family member 2B vs. Ensembl Yeast
Match: MSB3 (Rab GTPase-activating protein; regulates endocytosis via inactivation of Vps21p at endosomes and vacuole fusion via inactivation of Ypt7p at vacuoles; also acts on Ypt52p and Sec4p; localizes to plasma membrane, sites of polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; similar to TBC-domain Tre2 oncogene; MSB3 has a paralog, MSB4, that arose from the whole genome duplication; human homolog USP6NL can complement yeast msb3 msb4 double null [Source:SGD;Acc:S000005237]) HSP 1 Score: 72.7886 bits (177), Expect = 1.431e-13 Identity = 69/263 (26.24%), Postives = 122/263 (46.39%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVI------KFAFNERSNPDDDSL-GLQIV-KDLHRTGCDTFATESER---------AILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAA--------HXXXXXXXXXXXXASCINNNHYE-----PPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKV 1357 G+P+E R W A +K + N+ + K ++ NP++ + L I+ +DL+RT D +S L+RVL+A++ +N ++GYCQ N LA ++L ++ EE + ++V + LP + NL+ ++ID V + ++P++ + H N + S N E PP+T + T WF++ F +P + L IWD + E S +F+ LA+ +L L K+ Sbjct: 223 GIPAEWRGNAWWHFARGQ---EKLNKNKGVYSQLLRKMKQIKKQNPNEKQVQDLDIIERDLNRTFPDNIHFQSSLHNKEGPPIIKSLRRVLVAFSLYNPKIGYCQSMNFLAGLLLLFLD--EERAFWMLVIITSRYLPGVHNI-NLEGVNIDQGVLMLCVKEYIPEVWSYIKPSIDHHQKNNKTFSPSNKKVLFNMQKNEFLYRLPPIT-LCTASWFMSCFVGVVPIETTLRIWDCLFYEESHFLFKVSLAVLKLSEHDLSKI 478
BLAST of TBC1 domain family member 2B vs. Ensembl Yeast
Match: GYP5 (GTPase-activating protein (GAP) for yeast Rab family members; involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; GYP5 has a paralog, GYL1, that arose from the whole genome duplication [Source:SGD;Acc:S000006170]) HSP 1 Score: 65.855 bits (159), Expect = 2.302e-11 Identity = 57/223 (25.56%), Postives = 96/223 (43.05%), Query Frame = 2 Query: 644 ARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSL-GLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFR 1309 A + G+P +IR +W +AN+ + + ++ D + L I +DL RT F E + L +V+ Y+ ++ VGY QG +AA +L + NE +S ++V L+ + F + L + + F L H P S N E + ++ QWFLT FA P + VL I+D + +EG E++ + Sbjct: 446 AHVTNGIPPQIRGIIWQLMANSKSREMEDIYETLL----------DTECLHEATIRRDLRRT---KFVAEDKMESLYKVIKVYSVYDPDVGYTQGMGFIAAPLL-INCENEAESFGLLVGLMKNYGLRELFLPGMPGLMLMLYQFDRLLEEHSP------------------SLYNRLIREGISSTMYATQWFLTFFAYKFPLEFVLRIFDIVFVEGIEVLLK 636
BLAST of TBC1 domain family member 2B vs. Ensembl Nematostella
Match: EDO34898 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN40]) HSP 1 Score: 331.643 bits (849), Expect = 1.232e-104 Identity = 171/353 (48.44%), Postives = 233/353 (66.01%), Query Frame = 2 Query: 731 DWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFA---TESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFS-SIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHL----SNYKAKENQMPLSLSSVDISQVGPGAVST 1765 DW + +KF FNERSNPDDD LG QIVKDLHRTGC F T ERA LKRVLLAYARWNK VGYCQGFNV+AA+IL+VM+R+EED+LK+M+Y++DH+LP +YF+ NL+ALS+DMAV R+ + + +P+L+ HL NLQ Q+ + + YEPPL NVFTMQWFLTLFATCLP ++VL +WDS++LEGSE++ R LAIW L +L V +D FY M L +++ G + ++ +Y++AP P PGL+ LR+++TYNI+PFS S A S G D + + ++GC G ++P + + + + P S S DI++ PG +T Sbjct: 2 DWQKTVKFCFNERSNPDDDELGSQIVKDLHRTGCAWFCGNDTPEERAALKRVLLAYARWNKSVGYCQGFNVIAALILQVMDRSEEDALKVMIYVIDHVLPTNYFSNNLRALSVDMAVCRDLMRLKLPRLSRHLENLQAQATAHHG---GTSVYEPPLINVFTMQWFLTLFATCLPQEIVLRVWDSVLLEGSEVLLRVALAIWAKLGKRLEDVETSDEFYGKMGLLIQEIAVGNLIDCRSIMQAVYSLAPFPLPGLAALREQYTYNIHPFSDSQEKAPRSLGH-----------ASSDEEEDDADLDNVGCLGVLLPFSEFSPPSPAKSSSDGETP-SRRSSDIAEASPGVFAT 339
BLAST of TBC1 domain family member 2B vs. Ensembl Nematostella
Match: EDO34047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQE4]) HSP 1 Score: 100.523 bits (249), Expect = 3.140e-23 Identity = 65/239 (27.20%), Postives = 123/239 (51.46%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTF----ATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVND 1363 G+PS R +VW+ ++ ++K + + + + DD + I+ D+ RT + +++S + LK +L+AYA N ++GYCQG N +A ++L ++ + EE + ++ ++ LP+ Y+A+++ L ++ V E + I +P L H I ++ ++F+ +WF+ L+ LP + VL IWDS+ EGS+I+ R + + L D+LL D Sbjct: 58 GVPSSHRAQVWMDISGARKRMKK-----LPGYYQSLLESELDDIVRNSILTDIDRTFPENIYFGSSSDSLKQKLKNILVAYAVHNPKIGYCQGLNYIAGLLLLII-KTEEPAFWLLEAMMMKRLPD-YYAKDMMGLQVEQEVLSELVKIKLPTLHHH------------IESIGLSY------SIFSTKWFICLYIDVLPVETVLRIWDSLFYEGSKILLRVAITLLALHQDKLLAAKD 271
BLAST of TBC1 domain family member 2B vs. Ensembl Nematostella
Match: EDO34196 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQ41]) HSP 1 Score: 95.1301 bits (235), Expect = 7.575e-22 Identity = 60/220 (27.27%), Postives = 108/220 (49.09%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQK------YDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEI 1300 G+P+E R ++W N+ + K Y + + A N + +P + L +++ L + +L+ VL+AY+ N VGYCQG N L AI + +++ EE++ +V +V+HI+P+ YF++ L A D V R+ L +P+L H N+++ ++ T WFLT+F P +L +WD+ + EG+++ Sbjct: 37 GIPNEYRSQIWRQCINHFVRGTKSMAGPNYYAHLLDSIASNIKFSPATKQIELDLLRTLPNNVHYNKPDANGIGMLRNVLMAYSWHNPEVGYCQGLNRLVAIAMLILK--EEEAFWCLVAIVEHIMPKDYFSRTLLAAQADQRVLRDLLMEKLPRLYTHFENVRVD------------------LSLITFNWFLTVFIDSFPIQTILRVWDTFLYEGNKV 236
BLAST of TBC1 domain family member 2B vs. Ensembl Nematostella
Match: EDO49828 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7REP1]) HSP 1 Score: 94.3597 bits (233), Expect = 1.461e-19 Identity = 67/239 (28.03%), Postives = 121/239 (50.63%), Query Frame = 2 Query: 659 GLPSEIRKKVWL--SLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVND 1363 G+P +R ++WL S A N I + +++ + S D +I +DLHR+ + A +S+ I L+RVL AYA N +GYCQ N++A+++L + EE + ++V + + +LP+ Y + + AL +D VF + H+P+L HL + + N+ ++ WFLTLF + +P ++I D +G++++F+ LA + +LL + D Sbjct: 520 GIPDNLRAEIWLIFSGAINEIETHPGYYVSLVEQCEGKSSLAFD-----EIERDLHRSLPEHPAFQSDVGIGALRRVLTAYAWRNPSIGYCQAMNIVASVLL--LYCTEEQAFWLLVAVCERLLPDYYNTKVVGAL-VDQGVFEDLTRDHLPELYDHLK-------------------DLGILNMISLSWFLTLFLSVMPFVCAVNIIDCFFYDGAKVLFQIALACLDANRTKLLSIED 731
BLAST of TBC1 domain family member 2B vs. Ensembl Nematostella
Match: EDO35021 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMP1]) HSP 1 Score: 83.9593 bits (206), Expect = 1.517e-16 Identity = 62/262 (23.66%), Postives = 121/262 (46.18%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQK-----YDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRT----GCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDG 1417 G+P +R +W+ ++ +QK + + +V++ + +E S QI KDL RT C + T + ++R+L + A +GYCQG ++ A +L +E EED+ + +++ + P SY++ L + D V R+ + ++P + + E L T+ WFLT FA+ + ++L IWD EGS +FR L + +L + +L ++++ + + + ++D Sbjct: 97 GIPHSMRAPIWMRISG---ALQKKINAEFTYKQVVRASSDENSPASK-----QIEKDLLRTMPNNACFSTPTSTGLLRMRRILRSLAWLYPDIGYCQGMGMIVASLLLFVE--EEDAFWLTSTIIEDLNPPSYYSSTLIGVQADQRVLRQLIVSYLPHTDQQ---------------LKEHDIELSL---ITLHWFLTAFASVVHTKILLRIWDIYFYEGSVTLFRATLGMLKLKQEYILTLDNSAQIFNVLSDIPGDITDA 330
BLAST of TBC1 domain family member 2B vs. Ensembl Medaka
Match: tbc1d30 (TBC1 domain family member 30 [Source:NCBI gene;Acc:101166922]) HSP 1 Score: 401.364 bits (1030), Expect = 7.542e-126 Identity = 187/337 (55.49%), Postives = 246/337 (73.00%), Query Frame = 2 Query: 563 DTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFAT---ESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGS 1564 DT+LKF +EP G F+QW +A+K VARLP G+P E RK+VWL+LA+ ++ DW + ++FAFNERSNPDDDSLG+QIVKDLHRTGC ++ E +R +LKRVLLA+ARWNK VGYCQGFNVLAA+ILEV E +E D+LK+M+YL+D +LP+SYFA NL+ALS+DMAVFR+ L + +P+L+ HL++LQ A+ YEPPLTNVFTMQWFLT+FATCLP VL IWDS+ EGSE++FR LAIWE L +++ AD FY TM LT ++ + + L+ +Y+MA PFP L+ LR+++TYNI PF P+++ GS Sbjct: 56 DTRLKFTIEPSLGKNGFQQWYDALKAVARLPTGVPKEWRKRVWLTLADQYLHSISIDWEKTLRFAFNERSNPDDDSLGIQIVKDLHRTGCSSYCGQEGEQDRVVLKRVLLAFARWNKTVGYCQGFNVLAALILEVTEGSESDALKVMIYLIDKVLPDSYFANNLRALSVDMAVFRDLLRLKLPRLSQHLHHLQKA-----ANREAGGSYEPPLTNVFTMQWFLTMFATCLPAHTVLRIWDSVFFEGSEVLFRVALAIWERLGERIEDCQTADEFYSTMGGLTQEMLEQNLIDATELMQEVYSMAAFPFPQLAELREKYTYNITPF---PTSVKPNGS 384
BLAST of TBC1 domain family member 2B vs. Ensembl Medaka
Match: ENSORLT00000025434.2 (TBC1 domain family member 2A-like [Source:NCBI gene;Acc:101163797]) HSP 1 Score: 132.88 bits (333), Expect = 1.338e-31 Identity = 84/258 (32.56%), Postives = 134/258 (51.94%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNR-VIKFAFNERSNPDDDSLGLQIVKDLHRTGCDT--FATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDG 1417 G+P E R +VW + + W+ V++ R+ P + +Q+ DLHRT F++ S A+ L+R+LL+++ N VGYCQG N LAAI L V++ NEED+ ++ +V+ I+PE Y+ +NL A + R L +P+LAAH + + T WFL +F LP D++L +WD+ + EG+++IFR LA+++ D +LK+ND Y +R T +SD Sbjct: 350 GVPQEYRSRVWRWMIRART---RTIWDSGVLQLCEKSRTFPHPATRQIQL--DLHRTLTTNQHFSSPSSPALQELRRILLSFSWHNPTVGYCQGLNRLAAIALLVLQ-NEEDAFWCLLAVVETIMPEDYYTKNLMASQV-----RRLLVEKLPRLAAHFEKHNID------------------VTLITFNWFLVVFVESLPSDILLPLWDAFLYEGTKVIFRYALALFKYKEDDILKINDGVEIYQYLRFFTKTVSDS 578
BLAST of TBC1 domain family member 2B vs. Ensembl Medaka
Match: tbc1d2b (TBC1 domain family member 2B [Source:NCBI gene;Acc:101174263]) HSP 1 Score: 105.145 bits (261), Expect = 1.740e-22 Identity = 80/291 (27.49%), Postives = 141/291 (48.45%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKY------DWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTN--VFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIY-NMAPMPFPGLSNLR 1498 G+P E R KVW + H V+K+ D+ + E+ NP + L +++ L +A+ S I L+ VL+A++ N +GYCQG N LAAI L + ++ED+ +V +V+ +P Y+ + L +D VF++ ++ +P+L AH +E + + + T WFL +F + D++ IWD+ + EG +IIFR LA+++ ++ LK++D+ + + +R T + D L+N + M P P + N R Sbjct: 628 GVPHEHRSKVWRWCVSFH--VKKFRDHLAPDYYETLLNVAREKPNPASKQIELDLLRTLPNN--KHYASPSAAGIQKLRNVLVAFSWRNPDIGYCQGLNRLAAITLLYL--DQEDAFWALVAIVEVFMPRDYYTKTLLGSQVDQRVFKDLMSEKLPRLHAH--------------------FEQQMVDFSLITFNWFLVVFVDSVVSDILFKIWDAFLFEGPKIIFRFALALFKYKEEEFLKLHDSTATFKYLRYFTRTILDS-----RKLMNIAFAGMNPFPMKQIHNRR 887
BLAST of TBC1 domain family member 2B vs. Ensembl Medaka
Match: tbc1d2b (TBC1 domain family member 2B [Source:NCBI gene;Acc:101174263]) HSP 1 Score: 104.76 bits (260), Expect = 2.129e-22 Identity = 80/291 (27.49%), Postives = 141/291 (48.45%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKY------DWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAI--LKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTN--VFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIY-NMAPMPFPGLSNLR 1498 G+P E R KVW + H V+K+ D+ + E+ NP + L +++ L +A+ S I L+ VL+A++ N +GYCQG N LAAI L + ++ED+ +V +V+ +P Y+ + L +D VF++ ++ +P+L AH +E + + + T WFL +F + D++ IWD+ + EG +IIFR LA+++ ++ LK++D+ + + +R T + D L+N + M P P + N R Sbjct: 669 GVPHEHRSKVWRWCVSFH--VKKFRDHLAPDYYETLLNVAREKPNPASKQIELDLLRTLPNN--KHYASPSAAGIQKLRNVLVAFSWRNPDIGYCQGLNRLAAITLLYL--DQEDAFWALVAIVEVFMPRDYYTKTLLGSQVDQRVFKDLMSEKLPRLHAH--------------------FEQQMVDFSLITFNWFLVVFVDSVVSDILFKIWDAFLFEGPKIIFRFALALFKYKEEEFLKLHDSTATFKYLRYFTRTILDS-----RKLMNIAFAGMNPFPMKQIHNRR 928
BLAST of TBC1 domain family member 2B vs. Ensembl Medaka
Match: tbc1d9 (TBC1 domain family member 9B [Source:NCBI gene;Acc:101165539]) HSP 1 Score: 101.293 bits (251), Expect = 3.351e-21 Identity = 77/276 (27.90%), Postives = 133/276 (48.19%), Query Frame = 2 Query: 659 GLPSEIRKKVWL--SLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCD--TFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMP 1474 G+P +R ++WL S A N I + +++ A + S + +I +DLHR+ + F E+ A L+RVL AYA N +GYCQ N++ +++L + EE++ ++V L + +LP+ Y + + AL +D VF E +P+L H+ E + + ++ WFLTLF + +P D + + D+ EG ++IF+ LA+ + + LL +D M L L D+++NR AP+P Sbjct: 500 GIPERLRGELWLLFSGAQNEIVSHPGYYGDLVEAAMGQCSLATE-----EIERDLHRSMPEHRAFQNETGIAALRRVLTAYAHRNPGIGYCQAMNIVTSVLL--LYCTEEEAFWLLVALCERMLPDYYNTRVVGAL-VDQGVFEELTRDFLPQLYEHMQ-------------------ELGVISTISLSWFLTLFLSAMPFDSAVLLIDNFFYEGIKVIFQVALAVLQDNMNALLCCSDEGE---AMTILGRYL--------DNVVNRQTVSAPIP 737
BLAST of TBC1 domain family member 2B vs. Planmine SMEST
Match: SMESG000078416.1 (SMESG000078416.1) HSP 1 Score: 1802.72 bits (4668), Expect = 0.000e+0 Identity = 938/941 (99.68%), Postives = 939/941 (99.79%), Query Frame = 2 Query: 86 MIDSEPCIVVDGIPDSHSESLFEKHECKNSGESVIDNLLFEIYDKWAYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYXXXXXXXXXTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTASHIIVSSTYPSLQNSMVNHLFLTRSSTHNVTQRPFLMRQNRXXXXXXXXXXXXXKPLGVDIIRTNRNVFNFEHMNSFNSYTIPESSVSSIRPAXXXXXXXXXXXXXXXXDVGTSCEDASTPRARSVSLSDLSNKQMTLLELSKIAQISYAPKVDVDKSDISPKVIDQIKSPDLNLVLERHHQRIQNGPPYLKCLKAKEDSLKILPLDDLNSLTEYGHTARWVAEHHMNSPYSIGISTEVTGIIRASSVICTSNKSSQNALFGTKLGLYKTMAQSRLYRSRINGILHSAYINELQRNTKLGMVNCE 2908 MIDSEPCI VDGIPDSHSESLFEKHECKNSGESVIDNLLFEIYDKWAYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHLNNLQLQSQQQNASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMR LTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNDTAEDDADEDEDYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYKKIKDKQKKTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTASHIIVSSTYPSLQNSMVNHLFLTRSSTHNVTQRPFLMRQNRLDSSASDSNSLSNKPLGVDIIRTNRNVFNFEHMNSFNSYTIPESSVSSIRPASDSSSVNRLRRSLSKSDVGTSCEDASTPRARSVSLSDLSNKQMTLLELSKIAQISYAPKVDVDKSDISPKV+DQIKSPDLNLVLERHHQRIQNGPPYLKCLKAKEDSLKILPLDDLNSLTEYGHTARWVAEHHMNSPYSIGISTEVTGIIRASSVICTSNKSSQNALFGTKLGLYKTMAQSRLYRSRINGILHSAYINELQRNTKLGMVNCE Sbjct: 1 MIDSEPCIAVDGIPDSHSESLFEKHECKNSGESVIDNLLFEIYDKWAYKCRHDSSWDSDTITSASDAVSGFAWRRSIGVSVNGSENELKHYTTISESTLNQKSIEELEKVKMNMKQSVAIFSSRLVRQLKRRDHALAKMQKNCDILTAILQASSLKRREDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHLNNLQLQSQQQNASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRDLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNDTAEDDADEDEDYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYKKIKDKQKKTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTASHIIVSSTYPSLQNSMVNHLFLTRSSTHNVTQRPFLMRQNRLDSSASDSNSLSNKPLGVDIIRTNRNVFNFEHMNSFNSYTIPESSVSSIRPASDSSSVNRLRRSLSKSDVGTSCEDASTPRARSVSLSDLSNKQMTLLELSKIAQISYAPKVDVDKSDISPKVVDQIKSPDLNLVLERHHQRIQNGPPYLKCLKAKEDSLKILPLDDLNSLTEYGHTARWVAEHHMNSPYSIGISTEVTGIIRASSVICTSNKSSQNALFGTKLGLYKTMAQSRLYRSRINGILHSAYINELQRNTKLGMVNCE 941
BLAST of TBC1 domain family member 2B vs. Planmine SMEST
Match: SMESG000078416.1 (SMESG000078416.1) HSP 1 Score: 1477.61 bits (3824), Expect = 0.000e+0 Identity = 781/783 (99.74%), Postives = 782/783 (99.87%), Query Frame = 2 Query: 560 EDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYXXXXXXXXXTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTASHIIVSSTYPSLQNSMVNHLFLTRSSTHNVTQRPFLMRQNRXXXXXXXXXXXXXKPLGVDIIRTNRNVFNFEHMNSFNSYTIPESSVSSIRPAXXXXXXXXXXXXXXXXDVGTSCEDASTPRARSVSLSDLSNKQMTLLELSKIAQISYAPKVDVDKSDISPKVIDQIKSPDLNLVLERHHQRIQNGPPYLKCLKAKEDSLKILPLDDLNSLTEYGHTARWVAEHHMNSPYSIGISTEVTGIIRASSVICTSNKSSQNALFGTKLGLYKTMAQSRLYRSRINGILHSAYINELQRNTKLGMVNCE 2908 EDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHLNNLQLQSQQQNASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMR LTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNDTAEDDADEDEDYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYKKIKDKQKKTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTASHIIVSSTYPSLQNSMVNHLFLTRSSTHNVTQRPFLMRQNRLDSSASDSNSLSNKPLGVDIIRTNRNVFNFEHMNSFNSYTIPESSVSSIRPASDSSSVNRLRRSLSKSDVGTSCEDASTPRARSVSLSDLSNKQMTLLELSKIAQISYAPKVDVDKSDISPKV+DQIKSPDLNLVLERHHQRIQNGPPYLKCLKAKEDSLKILPLDDLNSLTEYGHTARWVAEHHMNSPYSIGISTEVTGIIRASSVICTSNKSSQNALFGTKLGLYKTMAQSRLYRSRINGILHSAYINELQRNTKLGMVNCE Sbjct: 51 EDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHLNNLQLQSQQQNASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRDLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNDTAEDDADEDEDYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYKKIKDKQKKTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTASHIIVSSTYPSLQNSMVNHLFLTRSSTHNVTQRPFLMRQNRLDSSASDSNSLSNKPLGVDIIRTNRNVFNFEHMNSFNSYTIPESSVSSIRPASDSSSVNRLRRSLSKSDVGTSCEDASTPRARSVSLSDLSNKQMTLLELSKIAQISYAPKVDVDKSDISPKVVDQIKSPDLNLVLERHHQRIQNGPPYLKCLKAKEDSLKILPLDDLNSLTEYGHTARWVAEHHMNSPYSIGISTEVTGIIRASSVICTSNKSSQNALFGTKLGLYKTMAQSRLYRSRINGILHSAYINELQRNTKLGMVNCE 833
BLAST of TBC1 domain family member 2B vs. Planmine SMEST
Match: SMESG000078416.1 (SMESG000078416.1) HSP 1 Score: 1476.84 bits (3822), Expect = 0.000e+0 Identity = 781/783 (99.74%), Postives = 782/783 (99.87%), Query Frame = 2 Query: 560 EDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNXXXXXXXXXXXXYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYXXXXXXXXXTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTASHIIVSSTYPSLQNSMVNHLFLTRSSTHNVTQRPFLMRQNRXXXXXXXXXXXXXKPLGVDIIRTNRNVFNFEHMNSFNSYTIPESSVSSIRPAXXXXXXXXXXXXXXXXDVGTSCEDASTPRARSVSLSDLSNKQMTLLELSKIAQISYAPKVDVDKSDISPKVIDQIKSPDLNLVLERHHQRIQNGPPYLKCLKAKEDSLKILPLDDLNSLTEYGHTARWVAEHHMNSPYSIGISTEVTGIIRASSVICTSNKSSQNALFGTKLGLYKTMAQSRLYRSRINGILHSAYINELQRNTKLGMVNCE 2908 EDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHLNNLQLQSQQQNASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMR LTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNDTAEDDADEDEDYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYKKIKDKQKKTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTASHIIVSSTYPSLQNSMVNHLFLTRSSTHNVTQRPFLMRQNRLDSSASDSNSLSNKPLGVDIIRTNRNVFNFEHMNSFNSYTIPESSVSSIRPASDSSSVNRLRRSLSKSDVGTSCEDASTPRARSVSLSDLSNKQMTLLELSKIAQISYAPKVDVDKSDISPKV+DQIKSPDLNLVLERHHQRIQNGPPYLKCLKAKEDSLKILPLDDLNSLTEYGHTARWVAEHHMNSPYSIGISTEVTGIIRASSVICTSNKSSQNALFGTKLGLYKTMAQSRLYRSRINGILHSAYINELQRNTKLGMVNCE Sbjct: 47 EDTKLKFVMEPKPGNEAFRQWCEAMKGVARLPLGLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNPDDDSLGLQIVKDLHRTGCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHLNNLQLQSQQQNASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRDLTNQLSDGLIAQPDHLINRIYNMAPMPFPGLSNLRDRFTYNINPFSSIPSAIVSYGSPGNDTAEDDADEDEDYKSKHVNKASIGCFGGMMPSNHLSNYKAKENQMPLSLSSVDISQVGPGAVSTSPSIHHNASPGATQERMCTDLITLESQYKKIKDKQKKTSLLMNNIGHEKISSKSQVLAPSRHGKRKSSVGRPNPTASHIIVSSTYPSLQNSMVNHLFLTRSSTHNVTQRPFLMRQNRLDSSASDSNSLSNKPLGVDIIRTNRNVFNFEHMNSFNSYTIPESSVSSIRPASDSSSVNRLRRSLSKSDVGTSCEDASTPRARSVSLSDLSNKQMTLLELSKIAQISYAPKVDVDKSDISPKVVDQIKSPDLNLVLERHHQRIQNGPPYLKCLKAKEDSLKILPLDDLNSLTEYGHTARWVAEHHMNSPYSIGISTEVTGIIRASSVICTSNKSSQNALFGTKLGLYKTMAQSRLYRSRINGILHSAYINELQRNTKLGMVNCE 829
BLAST of TBC1 domain family member 2B vs. Planmine SMEST
Match: SMESG000042564.1 (SMESG000042564.1) HSP 1 Score: 88.5817 bits (218), Expect = 1.718e-18 Identity = 70/238 (29.41%), Postives = 107/238 (44.96%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNR--VIKFAFNERSNPDDDSLGLQIVKDLHRTG------CDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPKLAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQL 1348 G+P E R +VW L+ + YD N+ K+ S P++ I+ D+ RT D ES L+R+L A+ N +GYCQG N +A +IL VM +EE + I L+ IL ESY+ + + +D V E L +P++ + + SC+ + +WF+ F LP L + D +M EG +I+FR LAI L D + Sbjct: 63 GIPDEYRPEVWFILSGAK---KMYDENKGSYDKWHSQSISEPNEAV----ILADVPRTFPENTKFLDRNHPESLLPHLQRILTAFVFKNPTIGYCQGMNFIAGLILMVMMPDEEKAFWIFDTLITEIL-ESYYIPGMLRIQVDCMVLEELLRNKLPQV------HHSITAKCEGSCV-----------ILGAKWFICAFVDVLPIQTCLRVLDCVMFEGDKILFRAALAIIRLNQDAI 275
BLAST of TBC1 domain family member 2B vs. Planmine SMEST
Match: SMESG000012909.1 (SMESG000012909.1) HSP 1 Score: 90.5077 bits (223), Expect = 3.501e-18 Identity = 67/263 (25.48%), Postives = 121/263 (46.01%), Query Frame = 2 Query: 659 GLPSEIRKKVWLSLANNHITVQKYDWNRVIKFAFNERSNP---DDDSLGLQIVKDLHRT----GCDTFATESERAILKRVLLAYARWNKRVGYCQGFNVLAAIILEVMERNEEDSLKIMVYLVDHILPESYFAQNLQALSIDMAVFREFLNIHVPK----LAAHXXXXXXXXXXXXASCINNNHYEPPLTNVFTMQWFLTLFATCLPPDLVLHIWDSIMLEGSEIIFRTGLAIWELLSDQLLKVNDADSFYCTMRCLTNQLSD 1414 G+P +R ++W+ ++ I + K ++ E N D QI KDL RT C + + + L+R+L A +GYCQG V+ + +L +E EED+ +M +++ +LP SY++ NL + D RE + ++PK LA H ++ T+ WFLT+F + L +L +WD EGS ++FR L + +L ++L+ ++ + + L ++++D Sbjct: 131 GIPHSLRPQLWMRMSGALIK------RKNCKTSYKEIVNATTSDHIMCSKQIEKDLVRTLPSNVCFSHISSTGIPRLRRILRGLAWLYPDIGYCQGMGVIVSHLLLFLE--EEDTFWLMCAIIEDLLPVSYYSTNLIGVQADQMTLRELIPKYLPKIHELLAEHDIE----------------------ISLITLHWFLTIFGSILNIRNLLRVWDLFFYEGSLVLFRIILGMIQLKESEMLEFDNTAQIFNCLSKLPSEITD 363 The following BLAST results are available for this feature:
BLAST of TBC1 domain family member 2B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TBC1 domain family member 2B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of TBC1 domain family member 2B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of TBC1 domain family member 2B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TBC1 domain family member 2B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TBC1 domain family member 2B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TBC1 domain family member 2B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TBC1 domain family member 2B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TBC1 domain family member 2B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TBC1 domain family member 2B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of TBC1 domain family member 2B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 4
BLAST of TBC1 domain family member 2B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TBC1 domain family member 2B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TBC1 domain family member 2B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30007341 ID=SMED30007341|Name=TBC1 domain family member 2B|organism=Schmidtea mediterranea sexual|type=transcript|length=3059bpback to top protein sequence of SMED30007341-orf-1 >SMED30007341-orf-1 ID=SMED30007341-orf-1|Name=SMED30007341-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=942bp MIDSEPCIVVDGIPDSHSESLFEKHECKNSGESVIDNLLFEIYDKWAYKCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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