Bromodomain containing 7

Overview
NameBromodomain containing 7
Smed IDSMED30007274
Length (bp)1986
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Bromodomain containing 7 (SMED30007274) t-SNE clustered cells

Violin plots show distribution of expression levels for Bromodomain containing 7 (SMED30007274) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Bromodomain containing 7 (SMED30007274) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Bromodomain containing 7 (SMED30007274) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30007274

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30007274SMESG000060992.1 SmedASXL_013969SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30007274SMESG000060992.1 SmedASXL_013969SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30007274SMESG000060992.1 dd_Smed_v4_8872_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30007274SMESG000060992.1 dd_Smed_v4_8872_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30007274SMESG000060992.1 dd_Smed_v4_8872_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30007274SMESG000060992.1 dd_Smed_v4_8872_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Human
Match: BRD7 (bromodomain containing 7 [Source:HGNC Symbol;Acc:HGNC:14310])

HSP 1 Score: 60.8474 bits (146), Expect = 6.465e-9
Identity = 31/69 (44.93%), Postives = 42/69 (60.87%), Query Frame = 2 
Query: 1319 IPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESS 1525
            + +G   G L+SG   L G+KED+RNKVT + YL+YG   S+ P YDS  +  SK+ SD +   Y E S
Sbjct:  369 VRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAPHYDSTFANISKDDSDLIYSTYGEDS 437
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Human
Match: BRD7 (bromodomain containing 7 [Source:HGNC Symbol;Acc:HGNC:14310])

HSP 1 Score: 60.8474 bits (146), Expect = 6.640e-9
Identity = 31/69 (44.93%), Postives = 42/69 (60.87%), Query Frame = 2 
Query: 1319 IPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESS 1525
            + +G   G L+SG   L G+KED+RNKVT + YL+YG   S+ P YDS  +  SK+ SD +   Y E S
Sbjct:  369 VRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAPHYDSTFANISKDDSDLIYSTYGEDS 437
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Celegans
Match: swsn-9 (SWI/SNF nucleosome remodeling complex component [Source:UniProtKB/TrEMBL;Acc:Q17581])

HSP 1 Score: 53.9138 bits (128), Expect = 2.627e-7
Identity = 33/96 (34.38%), Postives = 46/96 (47.92%), Query Frame = 2 
Query: 1301 NDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQ--------CDESSEL 1564
            N+  R + IGD VG L+ GT  +    + R      ++YL+YG   SF P YDS  +  +KE +D  LR Y + S   D          C E SE+
Sbjct:  357 NNAPRRVTIGDIVGPLEEGTPGMIQMADHRLFSQAPVNYLNYGPYSSFAPMYDSTWATMTKEDTDLFLRTYGDKSNASDVMSMRRFVGDCPEFSEI 452
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Celegans
Match: swsn-9 (SWI/SNF nucleosome remodeling complex component [Source:UniProtKB/TrEMBL;Acc:Q17581])

HSP 1 Score: 53.9138 bits (128), Expect = 2.627e-7
Identity = 33/96 (34.38%), Postives = 46/96 (47.92%), Query Frame = 2 
Query: 1301 NDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQ--------CDESSEL 1564
            N+  R + IGD VG L+ GT  +    + R      ++YL+YG   SF P YDS  +  +KE +D  LR Y + S   D          C E SE+
Sbjct:  357 NNAPRRVTIGDIVGPLEEGTPGMIQMADHRLFSQAPVNYLNYGPYSSFAPMYDSTWATMTKEDTDLFLRTYGDKSNASDVMSMRRFVGDCPEFSEI 452
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Celegans
Match: swsn-9 (SWI/SNF nucleosome remodeling complex component [Source:UniProtKB/TrEMBL;Acc:Q17581])

HSP 1 Score: 53.9138 bits (128), Expect = 3.183e-7
Identity = 33/96 (34.38%), Postives = 46/96 (47.92%), Query Frame = 2 
Query: 1301 NDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQ--------CDESSEL 1564
            N+  R + IGD VG L+ GT  +    + R      ++YL+YG   SF P YDS  +  +KE +D  LR Y + S   D          C E SE+
Sbjct:  357 NNAPRRVTIGDIVGPLEEGTPGMIQMADHRLFSQAPVNYLNYGPYSSFAPMYDSTWATMTKEDTDLFLRTYGDKSNASDVMSMRRFVGDCPEFSEI 452
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Celegans
Match: swsn-9 (SWI/SNF nucleosome remodeling complex component [Source:UniProtKB/TrEMBL;Acc:Q17581])

HSP 1 Score: 53.9138 bits (128), Expect = 3.183e-7
Identity = 33/96 (34.38%), Postives = 46/96 (47.92%), Query Frame = 2 
Query: 1301 NDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQ--------CDESSEL 1564
            N+  R + IGD VG L+ GT  +    + R      ++YL+YG   SF P YDS  +  +KE +D  LR Y + S   D          C E SE+
Sbjct:  357 NNAPRRVTIGDIVGPLEEGTPGMIQMADHRLFSQAPVNYLNYGPYSSFAPMYDSTWATMTKEDTDLFLRTYGDKSNASDVMSMRRFVGDCPEFSEI 452
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Celegans
Match: swsn-9 (SWI/SNF nucleosome remodeling complex component [Source:UniProtKB/TrEMBL;Acc:Q17581])

HSP 1 Score: 53.9138 bits (128), Expect = 3.183e-7
Identity = 33/96 (34.38%), Postives = 46/96 (47.92%), Query Frame = 2 
Query: 1301 NDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQ--------CDESSEL 1564
            N+  R + IGD VG L+ GT  +    + R      ++YL+YG   SF P YDS  +  +KE +D  LR Y + S   D          C E SE+
Sbjct:  357 NNAPRRVTIGDIVGPLEEGTPGMIQMADHRLFSQAPVNYLNYGPYSSFAPMYDSTWATMTKEDTDLFLRTYGDKSNASDVMSMRRFVGDCPEFSEI 452
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Fly
Match: CG7154 (gene:FBgn0031947 transcript:FBtr0079488)

HSP 1 Score: 60.8474 bits (146), Expect = 3.440e-9
Identity = 29/75 (38.67%), Postives = 44/75 (58.67%), Query Frame = 2 
Query: 1310 ERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGD 1534
            ER++ IGD VG L+ G+  L   + D+RN V  +  L+YG   SF P++DS  S  S E +  +LR Y ++S  +
Sbjct:  514 ERVVTIGDLVGKLQKGSAQLQTRQVDKRNAVRTVKSLNYGAFASFAPTFDSRFSTLSAEETQLVLRTYGDASSAE 588
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Zebrafish
Match: brd7 (bromodomain containing 7 [Source:ZFIN;Acc:ZDB-GENE-040426-2687])

HSP 1 Score: 62.3882 bits (150), Expect = 1.381e-9
Identity = 34/95 (35.79%), Postives = 53/95 (55.79%), Query Frame = 2 
Query: 1259 TILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQ 1543
            T L ++NP +    +     + +G   G L++G   L G+KED+RN VT ++Y++YG   S+ P+YDS  +  SKE SD +   Y E S   D +
Sbjct:  339 TTLGILNPVDLSAGDPGYCPVKLGMMGGRLQTGINTLQGFKEDKRNMVTPVAYMNYGPFTSYAPTYDSSFANISKEDSDLIYSFYGEDSSQPDSE 433
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Xenopus
Match: brd7 (bromodomain containing 7 [Source:NCBI gene;Acc:493370])

HSP 1 Score: 54.6842 bits (130), Expect = 3.532e-7
Identity = 27/58 (46.55%), Postives = 38/58 (65.52%), Query Frame = 2 
Query: 1346 LKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSE 1519
            L++G  +L G+KED+RNKVT + YL+YG   S+ P YDS  +  SK+ SD +   Y E
Sbjct:  339 LQAGVNSLQGFKEDKRNKVTPVLYLNYGPFTSYAPCYDSTFANVSKDDSDLIYSTYGE 396
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Xenopus
Match: brd7 (bromodomain containing 7 [Source:NCBI gene;Acc:493370])

HSP 1 Score: 54.6842 bits (130), Expect = 4.246e-7
Identity = 27/58 (46.55%), Postives = 38/58 (65.52%), Query Frame = 2 
Query: 1346 LKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSE 1519
            L++G  +L G+KED+RNKVT + YL+YG   S+ P YDS  +  SK+ SD +   Y E
Sbjct:  383 LQAGVNSLQGFKEDKRNKVTPVLYLNYGPFTSYAPCYDSTFANVSKDDSDLIYSTYGE 440
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Xenopus
Match: brd7 (bromodomain containing 7 [Source:NCBI gene;Acc:493370])

HSP 1 Score: 54.6842 bits (130), Expect = 4.617e-7
Identity = 27/58 (46.55%), Postives = 38/58 (65.52%), Query Frame = 2 
Query: 1346 LKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSE 1519
            L++G  +L G+KED+RNKVT + YL+YG   S+ P YDS  +  SK+ SD +   Y E
Sbjct:  383 LQAGVNSLQGFKEDKRNKVTPVLYLNYGPFTSYAPCYDSTFANVSKDDSDLIYSTYGE 440
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Mouse
Match: Brd7 (bromodomain containing 7 [Source:MGI Symbol;Acc:MGI:1349766])

HSP 1 Score: 59.6918 bits (143), Expect = 9.394e-9
Identity = 30/69 (43.48%), Postives = 42/69 (60.87%), Query Frame = 2 
Query: 1319 IPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESS 1525
            + +G   G L+SG   L G+KED+RN+VT + YL+YG   S+ P YDS  +  SK+ SD +   Y E S
Sbjct:  369 VRLGMTTGRLQSGVNTLQGFKEDKRNRVTPVLYLNYGPYSSYAPHYDSTFANISKDDSDLIYSTYGEDS 437
[Close]
BLAST of Bromodomain containing 7 vs. UniProt/SwissProt
Match: sp|Q5ZKG2|BRD7_CHICK (Bromodomain-containing protein 7 OS=Gallus gallus OX=9031 GN=BRD7 PE=2 SV=1)

HSP 1 Score: 65.855 bits (159), Expect = 8.147e-10
Identity = 37/89 (41.57%), Postives = 51/89 (57.30%), Query Frame = 2 
Query: 1259 TILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESS 1525
            T L L+NP +          + +G   G L+SG   L G+KED+RNKVT ++YL+YG   S+ P+YDS  +  SKE SD +   Y E S
Sbjct:  349 TTLGLLNPVDLTAGEAGYCPVKLGMTAGRLQSGVNMLQGFKEDKRNKVTPVTYLNYGPYSSYAPTYDSTFANISKEDSDLIYSTYGEDS 437
[Close]
BLAST of Bromodomain containing 7 vs. UniProt/SwissProt
Match: sp|Q9NPI1|BRD7_HUMAN (Bromodomain-containing protein 7 OS=Homo sapiens OX=9606 GN=BRD7 PE=1 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 3.105e-8
Identity = 31/69 (44.93%), Postives = 42/69 (60.87%), Query Frame = 2 
Query: 1319 IPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESS 1525
            + +G   G L+SG   L G+KED+RNKVT + YL+YG   S+ P YDS  +  SK+ SD +   Y E S
Sbjct:  369 VRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAPHYDSTFANISKDDSDLIYSTYGEDS 437
[Close]
BLAST of Bromodomain containing 7 vs. UniProt/SwissProt
Match: sp|Q5R8B0|BRD7_PONAB (Bromodomain-containing protein 7 OS=Pongo abelii OX=9601 GN=BRD7 PE=2 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 3.533e-8
Identity = 31/69 (44.93%), Postives = 42/69 (60.87%), Query Frame = 2 
Query: 1319 IPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESS 1525
            + +G   G L+SG   L G+KED+RNKVT + YL+YG   S+ P YDS  +  SK+ SD +   Y E S
Sbjct:  369 VRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAPHYDSTFANISKDDSDLIYSTYGEDS 437
[Close]
BLAST of Bromodomain containing 7 vs. UniProt/SwissProt
Match: sp|O88665|BRD7_MOUSE (Bromodomain-containing protein 7 OS=Mus musculus OX=10090 GN=Brd7 PE=1 SV=1)

HSP 1 Score: 59.6918 bits (143), Expect = 6.571e-8
Identity = 30/69 (43.48%), Postives = 42/69 (60.87%), Query Frame = 2 
Query: 1319 IPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESS 1525
            + +G   G L+SG   L G+KED+RN+VT + YL+YG   S+ P YDS  +  SK+ SD +   Y E S
Sbjct:  369 VRLGMTTGRLQSGVNTLQGFKEDKRNRVTPVLYLNYGPYSSYAPHYDSTFANISKDDSDLIYSTYGEDS 437
[Close]
BLAST of Bromodomain containing 7 vs. TrEMBL
Match: A0A448X704 (Uncharacterized protein (Fragment) OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS23165 PE=4 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 1.104e-16
Identity = 43/82 (52.44%), Postives = 57/82 (69.51%), Query Frame = 2 
Query: 1265 LNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQN--LAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLL 1504
            LNL+NP NRG+++ +E II IGD+VG ++ G       GY+EDRRNKV   SYLDYG   SFGP  D+G ++C++  SD LL
Sbjct:   54 LNLLNPDNRGRVSRHESIITIGDEVGPVRGGVSAPPWGGYREDRRNKVVPYSYLDYGPFASFGPRVDTGAAHCTRSASDLLL 135
[Close]
BLAST of Bromodomain containing 7 vs. TrEMBL
Match: A0A075A571 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_02876 PE=4 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 9.479e-16
Identity = 45/84 (53.57%), Postives = 59/84 (70.24%), Query Frame = 2 
Query: 1259 TILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNL--AGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLL 1504
            T L ++NP N G +N  ERI PIG++VG+LKSG+  L   GY+EDRRNKV   +YL+YG  +SF P YDSG S+CS E +  +L
Sbjct:  246 TALAILNPDNHGIVNRNERIRPIGEEVGSLKSGSYLLPNGGYREDRRNKVIPYTYLNYGPFYSFAPHYDSGASHCSPEANQLVL 329
[Close]
BLAST of Bromodomain containing 7 vs. TrEMBL
Match: A0A1S8X7K2 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=X801_01426 PE=4 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 9.506e-16
Identity = 45/84 (53.57%), Postives = 59/84 (70.24%), Query Frame = 2 
Query: 1259 TILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNL--AGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLL 1504
            T L ++NP N G +N  ERI PIG++VG+LKSG+  L   GY+EDRRNKV   +YL+YG  +SF P YDSG S+CS E +  +L
Sbjct:  275 TALAILNPDNHGIVNRNERIRPIGEEVGSLKSGSYLLPNGGYREDRRNKVIPYTYLNYGPFYSFAPHYDSGASHCSPEANQLVL 358
[Close]
BLAST of Bromodomain containing 7 vs. TrEMBL
Match: A0A3R7ELU0 (Bromodomain-containing protein 7 OS=Clonorchis sinensis OX=79923 GN=BRD7 PE=4 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 2.732e-15
Identity = 45/84 (53.57%), Postives = 58/84 (69.05%), Query Frame = 2 
Query: 1259 TILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNL--AGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLL 1504
            T L ++NP N G +N  ERI PIG++VG LKSG+  L   GY+EDRRNKV   +YL+YG  +SF P YDSG S+CS E +  +L
Sbjct:  215 TTLTILNPDNHGIVNRNERIRPIGEEVGPLKSGSYLLPNGGYREDRRNKVIPYTYLNYGPFYSFAPHYDSGASHCSPEANQLVL 298
[Close]
BLAST of Bromodomain containing 7 vs. TrEMBL
Match: A0A504YDH3 (Bromo domain-containing protein OS=Fasciola gigantica OX=46835 GN=FGIG_04884 PE=4 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 3.744e-15
Identity = 44/84 (52.38%), Postives = 58/84 (69.05%), Query Frame = 2 
Query: 1259 TILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNL--AGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLL 1504
            T L ++NP NRG ++  ER+  IGD+VG LKSG+  L   GY+EDRRNKV   +YLDYG  +SF P +DSG S+CS E +  +L
Sbjct:  234 TYLGVLNPDNRGVVSRTERVRSIGDEVGVLKSGSPLLPNGGYREDRRNKVIPYTYLDYGPYYSFAPRFDSGASHCSPEANRLIL 317
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Cavefish
Match: brd7 (bromodomain containing 7 [Source:NCBI gene;Acc:103045632])

HSP 1 Score: 62.003 bits (149), Expect = 1.299e-9
Identity = 33/89 (37.08%), Postives = 52/89 (58.43%), Query Frame = 2 
Query: 1259 TILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESS 1525
            T L ++NP +    +     + +G   G L++G   L G+KED+RN+VT ++Y++YG   S+ P+YDS  +  SKE SD +   Y E S
Sbjct:  348 TTLGILNPADLNVGDPGYCPVKLGMMGGRLQTGVNTLQGFKEDKRNRVTPVTYMNYGPFSSYAPTYDSSFANISKEESDLIYSFYGEES 436
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Cavefish
Match: brd7 (bromodomain containing 7 [Source:NCBI gene;Acc:103045632])

HSP 1 Score: 61.2326 bits (147), Expect = 2.170e-9
Identity = 33/90 (36.67%), Postives = 52/90 (57.78%), Query Frame = 2 
Query: 1259 TILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSC 1528
            T L ++NP +    +     + +G   G L++G   L G+KED+RN+VT ++Y++YG   S+ P+YDS  +  SKE SD +   Y E S 
Sbjct:  336 TTLGILNPADLNVGDPGYCPVKLGMMGGRLQTGVNTLQGFKEDKRNRVTPVTYMNYGPFSSYAPTYDSSFANISKEESDLIYSFYGEESS 425
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Cavefish
Match: ENSAMXT00000050348.1 (pep primary_assembly:Astyanax_mexicanus-2.0:25:32559927:32561965:1 gene:ENSAMXG00000040699.1 transcript:ENSAMXT00000050348.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.2174 bits (121), Expect = 2.847e-8
Identity = 21/48 (43.75%), Postives = 34/48 (70.83%), Query Frame = 2 
Query: 1319 IPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDS 1462
            + +G   G L++G   L G+KED+RN+VT ++Y++YG   S+ P+YDS
Sbjct:    1 VKLGMMGGRLQTGVNTLQGFKEDKRNRVTPVTYMNYGPFSSYAPTYDS 48
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005457.1 (pep scaffold:Pmarinus_7.0:GL476632:176391:216820:1 gene:ENSPMAG00000004922.1 transcript:ENSPMAT00000005457.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 66.6254 bits (161), Expect = 1.020e-11
Identity = 36/89 (40.45%), Postives = 53/89 (59.55%), Query Frame = 2 
Query: 1259 TILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESS 1525
            T L ++NP +  +   Y   + +G  VG L+ GT  L G+KED+RN++T ++YL+YG   +F P YDS  S  SKE SD L   Y + +
Sbjct:  346 TTLAIVNPADSKKGESYP--VTLGMLVGKLQFGTSCLQGFKEDKRNRITPVTYLNYGPFSTFAPQYDSTFSNLSKEESDVLYSTYGDQA 432
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Nematostella
Match: EDO28093 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7F8])

HSP 1 Score: 55.4546 bits (132), Expect = 1.379e-9
Identity = 33/85 (38.82%), Postives = 47/85 (55.29%), Query Frame = 2 
Query: 1259 TILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNY 1513
            T L ++NP +   ++       +G  VG + +G+   A +KED+RNK T +SYL YG   SF P+YDS  +  SK  SD L   Y
Sbjct:   10 TSLAVINPDSSQVLSPESLPCNLGTVVGKVATGSHITATFKEDKRNKATPVSYLMYGPFGSFAPTYDSSRATISKGESDLLYSTY 94
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Nematostella
Match: EDO45971 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR96])

HSP 1 Score: 56.9954 bits (136), Expect = 1.857e-8
Identity = 29/63 (46.03%), Postives = 38/63 (60.32%), Query Frame = 2 
Query: 1325 IGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNY 1513
            +G  VG + +G+   A +KED+RNK T +SYL YG   SF P+YDS  +  SK  SD L   Y
Sbjct:  452 LGTVVGKVATGSHITATFKEDKRNKATPVSYLMYGPFGSFAPTYDSSRATISKGESDLLYSTY 514
[Close]
BLAST of Bromodomain containing 7 vs. Ensembl Medaka
Match: brd7 (bromodomain containing 7 [Source:NCBI gene;Acc:101164713])

HSP 1 Score: 50.8322 bits (120), Expect = 3.456e-6
Identity = 29/89 (32.58%), Postives = 49/89 (55.06%), Query Frame = 2 
Query: 1259 TILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESS 1525
            T L ++NP +    +     + +G     L++G   L  ++ED+RN++  +SYL+YG   S+ P+YDS  +  SK+ SD +   Y E S
Sbjct:  320 TTLGILNPADPSVGDAGYCPVKLGMMSHRLQNGVNCLQSFREDKRNRINPVSYLNYGPFTSYAPTYDSSFANISKDDSDLVYSLYGEES 408
[Close]
BLAST of Bromodomain containing 7 vs. Planmine SMEST
Match: SMESG000060992.1 (SMESG000060992.1)

HSP 1 Score: 1080.86 bits (2794), Expect = 0.000e+0
Identity = 549/551 (99.64%), Postives = 550/551 (99.82%), Query Frame = 2 
Query:   47 MDDANNLDKSESTDENDERSETETECFEKTDSEIISQSDNIQEYRCLECNVNFQIYEDFQKHKVYKHPIVIYKCTIDNCQRWFSSRKSRDKHSENSKSQLHKSMYFKSPPLNAIFIESATEEQLEILRICKNENFKFLIQRFSDNSSIKSKYKRGPKPKMSNESDFLVGLPRDQLKRKLMESVVEKLESSTNNKTNQESSLKFSKRTTIEQTSSTARHGNGNSPKFISKNHRIKSSDCNNKNCTDDVISNKPKPIPDLSHIKVPILSLDASCTIGKFAEDLINLLTIYDPAEFFKYPLIDYFAPSSSQLGKQIDMKTIHKRLKEGKYCERXXXXXXXXXXMYGNGFQSFVEKSQGWCEAGKLYQTALVNIQNAKKKFPASKPTNETSLTLEXXXXXXXXXXXXXTILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQCDESSELATTPEITIGDDFSLYLMNVFTRDFIKSSPPSDWRKADDQSQSSKP 1699
            MDDANNLDKSESTDENDERSETETECFEKTDSEIISQSDNIQEYRCLECNVNFQIYEDFQKHKVYKHPIVIYKCTIDNCQRWFSSRKSRDKHSENSKSQLHKSMYFKSPPLNAIFIESATEEQLEILRICKNENFKFLIQRFSDNSSIKSKYKRGPKPKMSNESDFLVGLPRDQLKRKLMESVVEKLESSTNNKTNQESSLKFSKRTTIEQTSSTARHGNGNSPKFISKNHRIKSSDCNNKNCTDDVISNKPKPIPDLSHIKVPILSLDASCTIGKFAEDLINLLTIYDPAEFFKYPLIDYFAPSSSQLGKQIDMKTIHKRLKEGKYCERLENLENDLLLMYGNGFQSFVEKSQGWCEAGKLYQTALVNIQNAKKKFPASKPTNETSLTLESVKSSDLKSSSASTILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQCDESSELATTPEITIGDDFSLYLMNVFTRDFIKSSPPSDWRKADDQSQS+ P
Sbjct:    1 MDDANNLDKSESTDENDERSETETECFEKTDSEIISQSDNIQEYRCLECNVNFQIYEDFQKHKVYKHPIVIYKCTIDNCQRWFSSRKSRDKHSENSKSQLHKSMYFKSPPLNAIFIESATEEQLEILRICKNENFKFLIQRFSDNSSIKSKYKRGPKPKMSNESDFLVGLPRDQLKRKLMESVVEKLESSTNNKTNQESSLKFSKRTTIEQTSSTARHGNGNSPKFISKNHRIKSSDCNNKNCTDDVISNKPKPIPDLSHIKVPILSLDASCTIGKFAEDLINLLTIYDPAEFFKYPLIDYFAPSSSQLGKQIDMKTIHKRLKEGKYCERLENLENDLLLMYGNGFQSFVEKSQGWCEAGKLYQTALVNIQNAKKKFPASKPTNETSLTLESVKSSDLKSSSASTILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQCDESSELATTPEITIGDDFSLYLMNVFTRDFIKSSPPSDWRKADDQSQSTTP 551

HSP 2 Score: 158.303 bits (399), Expect = 8.947e-41
Identity = 78/78 (100.00%), Postives = 78/78 (100.00%), Query Frame = 3 
Query: 1734 TPPPNKETDSSTEDNNDAANSSLQTLLDESWKDLARLKSSNYQRLSKLQLQPSNEEQMKTNPQSITNLNMIRKALNCK 1967
            TPPPNKETDSSTEDNNDAANSSLQTLLDESWKDLARLKSSNYQRLSKLQLQPSNEEQMKTNPQSITNLNMIRKALNCK
Sbjct:  550 TPPPNKETDSSTEDNNDAANSSLQTLLDESWKDLARLKSSNYQRLSKLQLQPSNEEQMKTNPQSITNLNMIRKALNCK 627
[Close]
BLAST of Bromodomain containing 7 vs. Planmine SMEST
Match: SMESG000060992.1 (SMESG000060992.1)

HSP 1 Score: 1052.35 bits (2720), Expect = 0.000e+0
Identity = 539/551 (97.82%), Postives = 540/551 (98.00%), Query Frame = 2 
Query:   47 MDDANNLDKSESTDENDERSETETECFEKTDSEIISQSDNIQEYRCLECNVNFQIYEDFQKHKVYKHPIVIYKCTIDNCQRWFSSRKSRDKHSENSKSQLHKSMYFKSPPLNAIFIESATEEQLEILRICKNENFKFLIQRFSDNSSIKSKYKRGPKPKMSNESDFLVGLPRDQLKRKLMESVVEKLESSTNNKTNQESSLKFSKRTTIEQTSSTARHGNGNSPKFISKNHRIKSSDCNNKNCTDDVISNKPKPIPDLSHIKVPILSLDASCTIGKFAEDLINLLTIYDPAEFFKYPLIDYFAPSSSQLGKQIDMKTIHKRLKEGKYCERXXXXXXXXXXMYGNGFQSFVEKSQGWCEAGKLYQTALVNIQNAKKKFPASKPTNETSLTLEXXXXXXXXXXXXXTILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQCDESSELATTPEITIGDDFSLYLMNVFTRDFIKSSPPSDWRKADDQSQSSKP 1699
            MDDANNLDKSESTDENDERSETETECFEKTDSEIISQSDNIQEYRCLECNVNFQIYEDFQKHKVYKHPIVIYKCTIDNCQRWFSSRKSRDKHSENSKSQLHKSMYFKSPPLNAIFIESATEEQLEILRICKNEN          NSSIKSKYKRGPKPKMSNESDFLVGLPRDQLKRKLMESVVEKLESSTNNKTNQESSLKFSKRTTIEQTSSTARHGNGNSPKFISKNHRIKSSDCNNKNCTDDVISNKPKPIPDLSHIKVPILSLDASCTIGKFAEDLINLLTIYDPAEFFKYPLIDYFAPSSSQLGKQIDMKTIHKRLKEGKYCERLENLENDLLLMYGNGFQSFVEKSQGWCEAGKLYQTALVNIQNAKKKFPASKPTNETSLTLESVKSSDLKSSSASTILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQCDESSELATTPEITIGDDFSLYLMNVFTRDFIKSSPPSDWRKADDQSQS+ P
Sbjct:    1 MDDANNLDKSESTDENDERSETETECFEKTDSEIISQSDNIQEYRCLECNVNFQIYEDFQKHKVYKHPIVIYKCTIDNCQRWFSSRKSRDKHSENSKSQLHKSMYFKSPPLNAIFIESATEEQLEILRICKNEN----------NSSIKSKYKRGPKPKMSNESDFLVGLPRDQLKRKLMESVVEKLESSTNNKTNQESSLKFSKRTTIEQTSSTARHGNGNSPKFISKNHRIKSSDCNNKNCTDDVISNKPKPIPDLSHIKVPILSLDASCTIGKFAEDLINLLTIYDPAEFFKYPLIDYFAPSSSQLGKQIDMKTIHKRLKEGKYCERLENLENDLLLMYGNGFQSFVEKSQGWCEAGKLYQTALVNIQNAKKKFPASKPTNETSLTLESVKSSDLKSSSASTILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRNKVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQCDESSELATTPEITIGDDFSLYLMNVFTRDFIKSSPPSDWRKADDQSQSTTP 541

HSP 2 Score: 158.303 bits (399), Expect = 8.706e-41
Identity = 78/78 (100.00%), Postives = 78/78 (100.00%), Query Frame = 3 
Query: 1734 TPPPNKETDSSTEDNNDAANSSLQTLLDESWKDLARLKSSNYQRLSKLQLQPSNEEQMKTNPQSITNLNMIRKALNCK 1967
            TPPPNKETDSSTEDNNDAANSSLQTLLDESWKDLARLKSSNYQRLSKLQLQPSNEEQMKTNPQSITNLNMIRKALNCK
Sbjct:  540 TPPPNKETDSSTEDNNDAANSSLQTLLDESWKDLARLKSSNYQRLSKLQLQPSNEEQMKTNPQSITNLNMIRKALNCK 617
The following BLAST results are available for this feature:
BLAST of Bromodomain containing 7 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
BRD76.465e-944.93bromodomain containing 7 [Source:HGNC Symbol;Acc:H... [more]
BRD76.640e-944.93bromodomain containing 7 [Source:HGNC Symbol;Acc:H... [more]
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BLAST of Bromodomain containing 7 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
swsn-92.627e-734.38SWI/SNF nucleosome remodeling complex component [... [more]
swsn-92.627e-734.38SWI/SNF nucleosome remodeling complex component [... [more]
swsn-93.183e-734.38SWI/SNF nucleosome remodeling complex component [... [more]
swsn-93.183e-734.38SWI/SNF nucleosome remodeling complex component [... [more]
swsn-93.183e-734.38SWI/SNF nucleosome remodeling complex component [... [more]
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BLAST of Bromodomain containing 7 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG71543.440e-938.67gene:FBgn0031947 transcript:FBtr0079488[more]
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BLAST of Bromodomain containing 7 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
brd71.381e-935.79bromodomain containing 7 [Source:ZFIN;Acc:ZDB-GENE... [more]
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BLAST of Bromodomain containing 7 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
brd73.532e-746.55bromodomain containing 7 [Source:NCBI gene;Acc:493... [more]
brd74.246e-746.55bromodomain containing 7 [Source:NCBI gene;Acc:493... [more]
brd74.617e-746.55bromodomain containing 7 [Source:NCBI gene;Acc:493... [more]
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BLAST of Bromodomain containing 7 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Brd79.394e-943.48bromodomain containing 7 [Source:MGI Symbol;Acc:MG... [more]
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BLAST of Bromodomain containing 7 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q5ZKG2|BRD7_CHICK8.147e-1041.57Bromodomain-containing protein 7 OS=Gallus gallus ... [more]
sp|Q9NPI1|BRD7_HUMAN3.105e-844.93Bromodomain-containing protein 7 OS=Homo sapiens O... [more]
sp|Q5R8B0|BRD7_PONAB3.533e-844.93Bromodomain-containing protein 7 OS=Pongo abelii O... [more]
sp|O88665|BRD7_MOUSE6.571e-843.48Bromodomain-containing protein 7 OS=Mus musculus O... [more]
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BLAST of Bromodomain containing 7 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A448X7041.104e-1652.44Uncharacterized protein (Fragment) OS=Protopolysto... [more]
A0A075A5719.479e-1653.57Uncharacterized protein OS=Opisthorchis viverrini ... [more]
A0A1S8X7K29.506e-1653.57Uncharacterized protein OS=Opisthorchis viverrini ... [more]
A0A3R7ELU02.732e-1553.57Bromodomain-containing protein 7 OS=Clonorchis sin... [more]
A0A504YDH33.744e-1552.38Bromo domain-containing protein OS=Fasciola gigant... [more]
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BLAST of Bromodomain containing 7 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
brd71.299e-937.08bromodomain containing 7 [Source:NCBI gene;Acc:103... [more]
brd72.170e-936.67bromodomain containing 7 [Source:NCBI gene;Acc:103... [more]
ENSAMXT00000050348.12.847e-843.75pep primary_assembly:Astyanax_mexicanus-2.0:25:325... [more]
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BLAST of Bromodomain containing 7 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000005457.11.020e-1140.45pep scaffold:Pmarinus_7.0:GL476632:176391:216820:1... [more]
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BLAST of Bromodomain containing 7 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Bromodomain containing 7 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO280931.379e-938.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459711.857e-846.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Bromodomain containing 7 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
brd73.456e-632.58bromodomain containing 7 [Source:NCBI gene;Acc:101... [more]
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BLAST of Bromodomain containing 7 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000060992.18.947e-4199.64SMESG000060992.1[more]
SMESG000060992.18.706e-4197.82SMESG000060992.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007274 ID=SMED30007274|Name=Bromodomain containing 7|organism=Schmidtea mediterranea sexual|type=transcript|length=1986bp
TTAATAAATAACTAAATTGTTTATATTAACGTTTCAAACATTTTAAATGG
ATGATGCGAATAATTTAGACAAATCCGAATCTACCGATGAAAATGATGAA
AGGTCTGAAACGGAGACAGAATGTTTTGAAAAGACAGACTCCGAAATTAT
ATCTCAAAGTGATAACATTCAAGAATATCGATGTTTAGAATGCAATGTTA
ATTTTCAAATTTATGAGGATTTTCAAAAGCATAAAGTCTACAAACATCCT
ATTGTTATTTATAAATGCACGATAGATAACTGTCAAAGGTGGTTTTCTTC
ACGTAAAAGTCGAGATAAACATTCAGAAAATTCAAAATCTCAACTTCATA
AATCCATGTATTTTAAATCCCCACCTCTAAATGCTATTTTTATTGAAAGT
GCTACTGAGGAACAACTTGAAATACTTAGAATATGCAAAAATGAAAATTT
CAAGTTTCTCATTCAACGATTTTCAGACAATTCGAGTATAAAATCAAAAT
ATAAACGCGGTCCGAAACCGAAAATGTCTAATGAAAGTGATTTTTTAGTC
GGATTACCCAGGGATCAATTAAAACGAAAGTTAATGGAAAGTGTTGTGGA
GAAATTGGAATCTAGCACTAATAACAAAACCAATCAAGAGTCTTCATTAA
AATTTTCAAAACGTACAACTATAGAACAAACATCATCTACTGCAAGGCAT
GGCAATGGAAACAGTCCAAAATTCATATCTAAAAATCATAGAATAAAGAG
TTCTGACTGTAATAATAAAAATTGTACAGATGATGTGATTTCAAATAAAC
CTAAACCCATTCCTGACTTGAGTCACATAAAAGTGCCTATTCTATCCCTA
GATGCTTCATGCACGATTGGAAAGTTTGCAGAAGATTTAATTAATTTATT
GACAATTTATGATCCTGCTGAATTTTTCAAATATCCATTGATTGATTATT
TTGCCCCGTCATCTTCTCAGCTCGGAAAACAAATTGATATGAAAACTATT
CATAAAAGATTGAAAGAGGGAAAATATTGTGAGAGGTTGGAAAATCTCGA
AAACGATCTTTTGTTGATGTACGGAAATGGGTTTCAAAGTTTTGTTGAGA
AATCCCAAGGCTGGTGTGAAGCAGGAAAACTTTATCAAACGGCTTTGGTA
AATATTCAAAATGCCAAAAAAAAATTTCCAGCCTCAAAACCCACCAATGA
AACGAGTTTAACGTTGGAATCGGTGAAAAGTTCCGATTTGAAGTCCAGCA
GCGCCAGTACTATTCTCAATTTGATGAATCCATACAATAGGGGGCAAATC
AATGATTACGAACGGATCATACCGATCGGGGATCAAGTTGGCACTCTGAA
ATCCGGAACACAGAATTTAGCTGGCTACAAAGAAGATAGAAGAAATAAAG
TCACAGTTTTATCGTACTTGGATTACGGCACGAATTTCTCATTTGGACCT
TCCTATGATTCCGGCAATTCGTATTGCTCGAAAGAAACCAGTGATTCCTT
GCTCAGAAATTACAGTGAGTCGAGTTGCGGTGACGATTACCAATGCGATG
AGTCCAGTGAGCTGGCAACAACGCCTGAGATTACGATAGGAGACGATTTC
AGTCTTTATTTGATGAATGTTTTCACCAGGGATTTCATTAAATCCAGCCC
ACCTTCCGATTGGAGGAAGGCTGACGACCAATCACAATCAAGTAAACCGT
AATTTTCATGTGTTTTTAGAATTTCATCTAGCAACACCGCCACCGAATAA
AGAAACTGACTCATCGACTGAGGATAATAATGATGCCGCCAATTCTAGCC
TTCAGACGCTATTGGATGAGAGTTGGAAAGATTTGGCGCGATTAAAATCA
TCCAATTATCAACGGTTATCAAAACTCCAATTGCAGCCGTCGAATGAAGA
ACAAATGAAAACTAATCCGCAATCCATTACTAATTTGAACATGATTCGTA
AAGCTCTCAATTGTAAATGATTTATACACACACGTG
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protein sequence of SMED30007274-orf-1

>SMED30007274-orf-1 ID=SMED30007274-orf-1|Name=SMED30007274-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=118bp
MFSPGISLNPAHLPIGGRLTTNHNQVNRNFHVFLEFHLATPPPNKETDSS
TEDNNDAANSSLQTLLDESWKDLARLKSSNYQRLSKLQLQPSNEEQMKTN
PQSITNLNMIRKALNCK*
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protein sequence of SMED30007274-orf-2

>SMED30007274-orf-2 ID=SMED30007274-orf-2|Name=SMED30007274-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=552bp
MDDANNLDKSESTDENDERSETETECFEKTDSEIISQSDNIQEYRCLECN
VNFQIYEDFQKHKVYKHPIVIYKCTIDNCQRWFSSRKSRDKHSENSKSQL
HKSMYFKSPPLNAIFIESATEEQLEILRICKNENFKFLIQRFSDNSSIKS
KYKRGPKPKMSNESDFLVGLPRDQLKRKLMESVVEKLESSTNNKTNQESS
LKFSKRTTIEQTSSTARHGNGNSPKFISKNHRIKSSDCNNKNCTDDVISN
KPKPIPDLSHIKVPILSLDASCTIGKFAEDLINLLTIYDPAEFFKYPLID
YFAPSSSQLGKQIDMKTIHKRLKEGKYCERLENLENDLLLMYGNGFQSFV
EKSQGWCEAGKLYQTALVNIQNAKKKFPASKPTNETSLTLESVKSSDLKS
SSASTILNLMNPYNRGQINDYERIIPIGDQVGTLKSGTQNLAGYKEDRRN
KVTVLSYLDYGTNFSFGPSYDSGNSYCSKETSDSLLRNYSESSCGDDYQC
DESSELATTPEITIGDDFSLYLMNVFTRDFIKSSPPSDWRKADDQSQSSK
P*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0002039p53 binding
GO:0003713transcription coactivator activity
GO:0003714transcription corepressor activity
GO:0008134transcription factor binding
GO:0042393histone binding
GO:0044212transcription regulatory region DNA binding
GO:0070577lysine-acetylated histone binding
GO:0003676nucleic acid binding
GO:0005515protein binding
GO:0046872metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0005654nucleoplasm
GO:0005829cytosol
GO:0005634nucleus
Vocabulary: biological process
TermDefinition
GO:0006357regulation of transcription from RNA polymerase II promoter
GO:0008285negative regulation of cell proliferation
GO:0035066positive regulation of histone acetylation
GO:0045892negative regulation of transcription, DNA-templated
GO:0045893positive regulation of transcription, DNA-templated
GO:2000134negative regulation of G1/S transition of mitotic cell cycle
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0007049cell cycle
GO:0016055Wnt signaling pathway
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR013087Znf_C2H2_type
IPR036427Bromodomain-like_sf
IPR015880Znf_C2H2-like
IPR001487Bromodomain
IPR021900DUF3512
IPR007087Znf_C2H2
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013087Zinc finger C2H2-typeSMARTSM00355c2h2final6coord: 72..101
e-value: 18.0
score: 11.0
coord: 44..67
e-value: 2.4
score: 17.1
IPR013087Zinc finger C2H2-typePROSITEPS00028ZINC_FINGER_C2H2_1coord: 46..67
IPR021900Protein of unknown function DUF3512PFAMPF12024DUF3512coord: 401..493
e-value: 8.6E-19
score: 68.0
IPR036427Bromodomain-like superfamilyGENE3DG3DSA:1.20.920.10coord: 271..400
e-value: 1.5E-5
score: 26.7
IPR036427Bromodomain-like superfamilySUPERFAMILYSSF47370Bromodomaincoord: 279..377
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 186..229
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..29
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 186..231
NoneNo IPR availablePANTHERPTHR22881BROMODOMAIN CONTAINING PROTEINcoord: 401..494
NoneNo IPR availablePANTHERPTHR22881:SF12BROMODOMAIN-CONTAINING PROTEIN 7coord: 401..494