PKD2-4

Query:  248 PNSCW-NRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVIL----------------------PVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTL 2305
            P   W  R   G+R LW TR  E++  +R+ Y+K+ LRELV Y+ FL VL I+++GM +   Y++T ++S LF  +  +    T F   ++  DFWKF  G LL+GLYW    +N    +D  +F++YEN L+G+PR+RQ+RVRN SCSIP D + EIK+C+  YS+SSE +  +G +N T W+YT+   L+ + + GI+ATY G G+Y++L+ T+ ++   + +L  N+W+DRGTRA  IDF+VYNANINLFC ++L+ EFP TGG++ S QF+ +KLIRYV + DFF+ ACE++F  FI YY+VEE LEI++ K  YF S WN LD+++++ S+     NI RT  V+ ++Q L  + N  PNFE L +WQ+QF+N+ A+T+F  W+K+FK+I+FN+TM+QLS T+SRC+KDL GFAIMFFIIF+A+AQL YL+FG QV+DFS  Q CI+T FRIILGD +FA++E A+R+ GP+YF  +VFF+FF+L NMFLAII DTY EVK +LA QK E E++D +++     L KL LKK+ + DI  ++  G     GK++FDE + +LK +G+ DAEIEA+F +YD DGD+ L E E   M+ +LE ++  LDL+       + +++    L                        VS EE++ L RRVDRM+++   IV+KID V+  LE +E+ K + RE +G +L+ +
Sbjct:  185 PRVAWAERLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSN-QTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFL-EDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGV 888          

Query:  206 KSTKDSIEETNF-INPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEI---EAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPV-------VSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEK 2257
            K  +D  +ET +    +SC      GIR LW T  TE+T  +R+LYIKTTLREL++YI FL  + ++++GMT+  AY++T ++S LF  +  +D   +F A ++ +DFW F  GPLL+ LYWT WYNN +      +F+YYEN L+G+PRLRQ++VRNDSC +  DF+ +I  C+  YS   E +  +G  N T W Y +   L    + G + +Y GGG+Y++L  ++  S   +  L   LW+DRGTR V IDF+VYNANINLFC ++LV EFP TGG + S Q RTVKLIRYV + DFF++ CE++F VFI YY+VEE LE+ + +  Y  SIWNILD++VI+ S+    F+I RTL V  ++  L+   N + +FE L FWQ Q++N+ A+ LF AW+K+FKYISFNKTMTQLS+TL+RC+KD+ GFA+MFFI+F A+AQLGYL+FG QV +FS    CI+T FRIILGDFD+  ++ A+RI GP YFV YVFFVFFVL NMFLAII DTY EVKEELA QK+E +++D +K+     L +L L+K+++ D+Q  +  G+     ++ F+++   L+  G+ + EI    A F ++D DG++ LDE EQ  M+++LE+++ +L+ EI+     I++  +    P        VS EE+  L RRV +++     +V++ID V   L+ +E+
Sbjct:   51 KKPEDEPQETAYRTQVSSCCLHICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTP-SDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGEQ----EIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAVGSKLKMLER 740          

Query:  296 ATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFT-TSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNIN-FTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELA-NQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKE-LEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESI 2251
            A++H    +  +++ I TTL+EL++Y  FL  L I++FGM     Y+   ++S LF  TS   +    F +  + +DFWKF+ GPLL GLYW +WYNN   +     + +YYEN L+G+PR+RQ++VRN++C + S FQ  + +C+  Y+ ++E   ++G Q +T W Y+ S+  ++  + G +  Y  GG+   L+ ++ ++ N  + L  N WI RGTR + IDF++YNAN+NLFC I+LV EFP TGG+L S QF +VKL+RYV   D+F+ +CE+ F +F+  +  +E  +IK  K  YF SIWN L++L+++       FN    + +  ++  L+ +   + +F  L  W + ++N+IAIT+F AW+K+FK+ISFNKTM+QLS+TLSRC KD+ GFAIMFFIIF A+AQLG+L+FG+QV+DFS  Q  I+  FRI+LGDF+FA ++ A+ I GP+YF+ ++FFVFFVL NMFLAII DTY EVK + +  ++ +FE+   +K+  + VL K  L                     + D D+     K++G GD    A  AR +   +  +  AEQ+   KE LE +  S++++  Y+               V+ EE+R L      ++     I  K++ V+  + ++
Sbjct:   12 ASKHKLHYR--KEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNT-NSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRL------------------KKAQKDEDK-----KTKGSGDL---AEQARREGFDENEIQNAEQMKKWKERLEKKYYSMEIQDDYQP--------------VTQEEFRELFLYAVELEKELHYINLKLNQVVRKVSAL 624          

Query:  296 ATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFT-TSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNIN-FTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELA-NQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKE-LEDQKNSLDLEIQYE 2095
            A++H    +  +++ I TTL+EL++Y  FL  L I++FGM     Y+   ++S LF  TS   +    F +  + +DFWKF+ GPLL GLYW +WYNN   +     + +YYEN L+G+PR+RQ++VRN++C + S FQ  + +C+  Y+ ++E   ++G Q +T W Y+ S+  ++  + G +  Y  GG+   L+ ++ ++ N  + L  N WI RGTR + IDF++YNAN+NLFC I+LV EFP TGG+L S QF +VKL+RYV   D+F+ +CE+ F +F+  +  +E  +IK  K  YF SIWN L++L+++       FN    + +  ++  L+ +   + +F  L  W + ++N+IAIT+F AW+K+FK+ISFNKTM+QLS+TLSRC KD+ GFAIMFFIIF A+AQLG+L+FG+QV+DFS  Q  I+  FRI+LGDF+FA ++ A+ I GP+YF+ ++FFVFFVL NMFLAII DTY EVK + +  ++ +FE+   +K+  + VL K  LK                    K   DE   + K++G GD   +A    +D   +  +  AEQ+   KE LE +  S++++  Y+
Sbjct:   12 ASKHKLHYR--KEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNT-NSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLK--------------------KAQKDE---DKKTKGSGDLAEQARREGFD---ENEIQNAEQMKKWKERLEKKYYSMEIQDDYQ 586          

Query:  296 ATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFT-TSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNIN-FTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELA-NQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKE-LEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEE 2155
            A++H    +  +++ I TTL+EL++Y  FL  L I++FGM     Y+   ++S LF  TS   +    F +  + +DFWKF+ GPLL GLYW +WYNN   +     + +YYEN L+G+PR+RQ++VRN++C + S FQ  + +C+  Y+ ++E   ++G Q +T W Y+ S+  ++  + G +  Y  GG+   L+ ++ ++ N  + L  N WI RGTR + IDF++YNAN+NLFC I+LV EFP TGG+L S QF +VKL+RYV   D+F+ +CE+ F +F+  +  +E  +IK  K  YF SIWN                       ++ ++  L+ +   + +F  L  W + ++N+IAIT+F AW+K+FK+ISFNKTM+QLS+TLSRC KD+ GFAIMFFIIF A+AQLG+L+FG+QV+DFS  Q  I+  FRI+LGDF+FA ++ A+ I GP+YF+ ++FFVFFVL NMFLAII DTY EVK + +  ++ +FE+   +K+  + VL K  L                     + D D+     K++G GD    A  AR +   +  +  AEQ+   KE LE +  S++++  Y+      + R++ L  V LE+
Sbjct:   12 ASKHKLHYR--KEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNT-NSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWN----------------------WLELLLLLLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRL------------------KKAQKDEDK-----KTKGSGDL---AEQARREGFDENEIQNAEQMKKWKERLEKKYYSMEIQDDYQPV-TQEEFRELFLYAVELEK 583          

Query:  197 EYGKSTKDSIEETNFINPNSCWNRFKNGI---RSLWATRHTEDTKVDRQLYIKTTLR---ELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLN-STQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRE 2278
            E+G S   S+    + +        K GI   ++L A+ H    K D +  IK T R   E+  Y  FL VLV ++F   ++Q+Y+++ ++S LF  S     +  F + T+  + W +L+  L+ G+YWT   N    ++D  N +YYENRL+G PR+R ++V NDSC++   FQ EIK+CFA Y    E K   G  +   ++Y  +  L+  +  G +A+YGGGGF   L  +   ++ + I TL  N WIDRG+RA+I+DF +YNANINLFC +KL+ E P +GG++ + +  T  L+ Y  S    ++  E +F  FI+Y+I EE   I   +  Y    WN++D++++ FS+   I ++ RT T  N + +++ N   +  F+ +T  +  + N+ A  +F+AWVKVFK+IS NKTM+QLS+TL+R +KD+ GFA+MF + F AFAQ GYL FG Q+ D+S L    + L R+ILGDF+F+ LE  +R FGP +F+ YVFFV F+L NMFLAII D+Y EVK ELA +K+   I D+   +   +  +           +     G+        ++++K+ L   GY + +I   F R++      +    +   +K  ED  + +   +  +K   +   RD          Y  LNRRVD+M  +   IV +I+ V   L++IEK + + ++
Sbjct:   21 EHGPSFDHSMVSEEYEHDKKKNPAQKEGISFSQALLASGHE---KSDGK--IKLTARSFMEVGGYAVFLIVLVYVAFAQNSIQSYYYSKVMSDLFVASTGASGAPAFGSCTSMDNIWDWLSQVLIPGIYWTETSN----STDNENMIYYENRLLGEPRIRMLKVTNDSCTVMKSFQREIKECFANYEEKLEDKTMVGDGSVDAFIYATAKELENLKTVGTIASYGGGGFVQRLPVAGSTEAQSAIATLKANRWIDRGSRAIIVDFALYNANINLFCVVKLLFELPASGGVITTPKLMTYDLLTYQTSGGTRMMIFEGIFCGFILYFIFEELFAIGRHRLHYLTQFWNLVDVVLLGFSVATIILSVNRTKTGVNRVNSVIENGLTNAPFDDVTSSENSYLNIKACVVFVAWVKVFKFISVNKTMSQLSSTLTRSAKDIGGFAVMFAVFFFAFAQFGYLCFGTQIADYSNLYNSAFALLRLILGDFNFSALESCNRFFGPAFFIAYVFFVSFILLNMFLAIINDSYVEVKAELARKKDGEGILDWFMNKVRGLTKR----------GKRPDAPGE-----DATYEDYKLMLYRAGYAEKDINEAFTRFN------VTSMTEHVPEKVAEDIADEV-ARMTEQKRNYMENHRD----------YANLNRRVDQMQESVFSIVDRIEGVNATLQTIEKQRVQQQD 680          

Query:  302 RHTEDTKV-DRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNN------INFTSDQINFLYYENRLIGLPRLRQVRVRNDS-CSIPSDFQGEIKQCFAAYSMSSESKDSY------------GQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNL----WIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVF--------IVYYIVEESLEIKMLK-----FEYF-------FSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVAND-NIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLH 1843
            R TE+ K+ D QL+I  T+R+++ +   L ++V++++       YW+   +S +   +  N    TF +     DFW +    L   L   +WY+         + +D+++      R +G+  +RQVR +  + C++   FQG I  C    +  +E K  Y            G   S  + Y  S  L T    G++ +Y GGG+ ++++ TQ +    I+TLFN L    WID  TRAVII+F+ YNA IN F  ++L+ E P +G  L +S   +V+LI+  GS    V   E+L++ F        IV+Y+      I  +K     F+         FS WN +D++V   ++   +   +R  T    ++   AN+ N + N      W++ F   +A  +F    K+ + + FN+ +  L+ATL      +  F I F    + F  + Y + G ++  +  L     T    +LG  D   ++   + F  +  + Y+     ++  +++ II   + E++ +   Q N++EI D++K +T+  L  L 
Sbjct: 2660 RDTENRKMRDEQLFI--TIRDMLCFFASLYIMVMLTYYCKDRHGYWYQLEMSTILNINQKNYGDNTFMSIQHADDFWDWARESLATAL-LASWYDGNPAYGMRAYMNDKVS------RSMGIGTIRQVRTKKSAECTMFKQFQGYINDCGEELTSKNEEKTLYMQAGWTELESENGTDASDEYTYKTSEELSTETVSGLLYSYSGGGYTISMSGTQAE----IITLFNKLDSERWIDDHTRAVIIEFSAYNAQINYFSVVQLLVEIPKSGIYLPNSWVESVRLIKSEGSDGTVVKYYEMLYIFFSVLIFVKEIVFYLYGRYKVITTMKPTRNPFKIVYQLALGNFSPWNFMDLIVGALAVASVLAYTIRQRTTNRAMEDFNANNGNSYINLTEQRNWEIVFSYCLAGAVFFTSCKMIRILRFNRRIGVLAATLDNALGAIVSFGIAFLFFSMTFNSVLYAVLGNKMGGYRSLMATFQTALAGMLGKLDVTSIQPISQ-FAFVVIMLYMIAGSKLVLQLYVTIIMFEFEEIRNDSEKQTNDYEIIDHIKYKTKRRLGLLE 3204          

Query:  584 NINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFE-YFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEF 1789
            N++F   +     YEN L+G PRLRQ+RVR +SC +   F      C+AAYS  +E  D       +P+   +   LD+T    ++A Y  GG+ VNL+  +  +   I  L +  W+DRG+R  +++F ++N N ++F  IKL+ E PPTGG++  +  +TVK+  +       +    + + + ++YY + E  EI+    + YF S+ NILD  +++      ++NI  +  V ++      +D  + + + L FW + + +++AI  FL W+K+FK+ISFNKT+ Q + TL RCSKDLAGF++MF I+F+A+AQLG L+FG +  DF      I T+ R+ILGDF +  +E A+R+ GP+YF+ Y+  VFF+L NMFLAII +TY  VK E+   ++  
Sbjct:  417 NMSFHHLEGRVFLYENLLLGPPRLRQIRVRKESCYVNDAFIRYFNTCYAAYSSGAE--DRKPMHKGSPFRTMHD--LDSTPIWTVLAFYRTGGYTVNLDYDKDRNVKIINDLKDIHWLDRGSRLCLVEFNLFNENTDIFQSIKLIAEIPPTGGVIPQAHLQTVKMYSFFTDRSMLMTVIYIFWYIMVIYYTIYEITEIRKSGIKIYFCSMLNILDCAILLGCYLALVYNIWHSFKVMSLT-ARAHSDVTYQSLDVLCFWNIIYVDMMAILAFLVWIKIFKFISFNKTLVQFTTTLKRCSKDLAGFSLMFGIVFLAYAQLGLLLFGTKHPDFRNFITSILTMIRMILGDFQYNLIEQANRVLGPIYFLTYILLVFFILLNMFLAIIMETYNTVKGEITQGRSHL 814          

Query:  626 ENRLIGLPRLRQVRVRNDSCSI-PSDFQGE--IKQCFAAYSMSSESKDSYGQQNSTPWVYTN------SSVLDTTEYQGIVATYGGGGFYVNL-NSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFF-SIWNILDILVII 1240
            ++ L+G+ RLRQ+RV N    + P  F     +      Y     S D Y +    PW+          ++L   ++ G + +Y     YV+L   +  +S   I  L  N W+   T AV IDFT+YN ++NLF    L  E  P GG++   Q  + KL+  V  + +  L   L++V+  + +   ++L +K+    +   S+WN LD+ + +
Sbjct:  210 QSVLLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYS-DKYWRIYE-PWIPIKMGFEFLDALLMNFDHVGSLNSYPELAGYVSLLARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPYTGLLALLIYVLVFIQF--AQTLAVKLWYEPHLLKSVWNKLDLFIFM 421          

Query:  626 ENRLIGLPRLRQVRVRNDSCSI-PSDFQGE--IKQCFAAYSMSSESKDSYGQQNSTPWVYTN------SSVLDTTEYQGIVATYGGGGFYVNL-NSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFF-SIWNILDILVII 1240
            ++ L+G+ RLRQ+RV N    + P  F     +      Y     S D Y +    PW+          ++L   ++ G + +Y     YV+L   +  +S   I  L  N W+   T AV IDFT+YN ++NLF    L  E  P GG++   Q  + KL+  V  + +  L   L++V+  + +   ++L +K+    +   S+WN LD+ + +
Sbjct:  210 QSVLLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYS-DKYWRIYE-PWIPIKMGFEFLDALLMNFDHVGSLNSYPELAGYVSLLARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPYTGLLALLIYVLVFIQF--AQTLAVKLWYEPHLLKSVWNKLDLFIFM 421          

Query:  632 RLIGLPRLRQVRVRND--SCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDT----TEYQGIVATYG-GGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKL-VGEFP---PTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTF---WQLQF--DNLIAITLFLAWVKVFKYISFNKTMTQLSATLS 1468
            RL+G+ RLRQ+R  ++    S+P   + +  + +          D Y     TPW+ + S   D       + G +  Y    G+ V L+ T+  S   I  L    W+D  T A+ +DF++YNA+ N F    L V +FP   P G   + S     +L  +       V    + ++ F   + ++   + + LK     ++W  +D +++  SL   +   VR     N++Q ++ +  I    + L F    QL +  D +  + + L  ++++K + F+ T    + T++
Sbjct:  208 RLLGVVRLRQLRTESNRLGLSLPVFTERDFSESWTLPYERVPYTDKYWPI-YTPWLPSVSVARDNLLMGINHVGHMFNYPESKGYKVLLSDTRHKSLKIIDYLMKKNWLDANTTALFMDFSLYNADANTFTVCTLWVEKFPYQYPDGHTRIESHTFVEQLREFTKFGMLMVFVFVVTWLQFTKAFFLKVWYDPRQLK-----TLWVQVDAMIVALSLVVGMIMSVR----DNLVQKMIKSVEIAVVVDFLDFREPAQLAYLEDVVTGLAVALVTMRLWKVLQFSATFQLFTKTIA 492          

Query:  638 IGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNST--------PWV-------YTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFE-YFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTL-VANDNIHPNFE-SLTFWQLQF---DNLIAITLFLAWVKVFKYISFNKTMTQ 1450
            IG+ RLRQ+R  +  C I     G  K  +   + + E +  Y + + T        P+V       + N  +L+   Y  ++      G+ V + ST+++    I  L +  W+D+ T A+ ID T+YNA+ NLF  I L  E  P G  L      +V ++  V +     L   +LFV  ++  +    +  K+          W ++D+ + I ++  ++  I+R +    ++Q +  A    + +F+  L   Q+ F     L+ IT    W KV ++ S  +  TQ
Sbjct:  191 IGVVRLRQMRPVD--CHI-----GLGKPEWDKKTYAPEWRLPYHRMHYTEKFWRIYDPFVPAEFEPSFLNGLLLNYDHYGYLLNYPEVAGYVVLMMSTKINCLKQIEYLRDYSWLDKNTSALFIDLTMYNADANLFTLITLRVENSPFGIQLPRVHVDSVSMLGNVETRSNSELL--ILFVYTVLVILFARGVFTKIWHHPAAAHEAWTMVDLAIYILNVFLTVLAIMRDIETDALLQIIETATKGQYLDFQRPLRLHQMLFIVKGFLVCITTLRLW-KVLQFASVFQHFTQ 472          

Query:  254 SCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQ----------YEKSEILNKTRDVILPVVSL------------EEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
            SC  R    +R LW TR   ++  +R++Y+KT LRE++ YI FL  L II++GM +   Y++T ++S LF  +  +    T F + +T  DFWKF  GP LNG+YW  WYNN +   +Q + +YYEN L+G+PRLRQ+RVRN+SCS+  D + E+  C+  YS ++E K  +G +N T W + + S L  + Y G V+TYGGGG+Y +L+ T+  S N +  L NNLW+DRGTRAV +DF++YN N+NLFC ++L+ EFP TGG + S QF+TV+L+RYV S D+FV  CE+ F +F++YY+VEE+LEI++ +  YF S+WN LD+L++  S+   I NI RT  V + +  L+ N + +PNFE L   Q+ F+NL AI +FL+WVK+FK+I+FNKTM QLS T+SRC+KDL GFAIMFFI+F+A+AQL YL+FG QVNDFS  Q CI+T FRIILGDFDF+++E A  + GP+YF  +VFF+F +L NMFLAII DTY EVK ++A Q++E EI D +K+     + KL LKK  I DI +++        GK+ FDE + +L+ +G+ DAEIEA+FA+YD DGD+ L E E   M+ +LE ++  LDLE            + +S+  ++  D      S             EE++ L RRVDRM+++   IV+KID V+  LE++E+ K + R+ +G IL+
Sbjct:  124 SCGKRILEKMRVLWDTRLLGESNSNREMYLKTVLREMITYILFLLTLCIITYGMVSTNMYYYTKVMSQLFLDTPLSSGEPTNFKSLSTMEDFWKFTEGPFLNGMYWELWYNNKSLPENQ-SLIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYDCYNVYSPANEDKAPFGPKNGTAWRFKDESSLGESSYWGQVSTYGGGGYYQDLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGAVPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFVLYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVLGPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSL----QQAAGKLSFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELTEHEHQQMRDDLEKEREDLDLEHSSLPRPASGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKMKRRDVLGRILD 823          

Query:  251 NSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQ-YEKS-EILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEAL-------ESIEKDKARSRE 2278
            + C + F   I+ LW T   +DTK + +L +K  L+EL+IYI FL  L ++++GMT+   Y++T  ++ LF       N  +F++    +D W ++ GPLL+ LYWT WYN+    +   +F+YYEN L+G+PR+RQ++V+ +SC +P+DF+ EI  CF  Y++  E   ++G  N T W Y +   +  + + G++ TY G GFY +L +T+ +S   +  L  NLW+DRGTR + IDFT YNANINLFC I+LV EFP TGG + S Q RTVKLIRYV + D+F++ CE++F VFI+YYIVEE LE ++ K  +F SIWNILDI+VI+ ++   +F+  RT+ V  ++  L+   +I+ +FE L FWQ Q++N+ A+ LF AW+K+FKYISFNKTMTQL++TL+RC+ D+ GFAIMFFI+F A+AQLGYL+FG +V  FS    CI+T FRIILGDFD+  ++ A+R+ GP+YF  YVFFVFFVL NMFLAII DTY EVK ELA+QK+EF+IAD +K+       KL LKK+KI D+Q A+ +G +    +++F +++  LK  G+ D EI A F+++D DG++ LD+ EQ  M++ELE+++++L  E++  E S E   + R+ + P    E+Y+ L  +V +++N+   I++K+D V+E +       ES + DK  +R+
Sbjct:   59 SGCCSFFFRAIKGLWGTALRKDTKENPELNVKANLKELLIYIVFLVDLCLLTYGMTSSATYYYTKAMTDLFVNLP-GSNGMSFSSIGCMNDVWTYMEGPLLDNLYWTKWYNDEPLENGNQSFIYYENLLLGVPRVRQLKVKQNSCKVPTDFKKEISDCFDVYNIKKEDDGAFGLINGTAWQYHSEKEIKGSSHWGLLTTYSGAGFYQDLTTTRDESAALLEDLRENLWLDRGTRVLFIDFTAYNANINLFCVIRLVVEFPATGGAIPSYQIRTVKLIRYVTTWDYFIIGCEIVFCVFILYYIVEEILEFRIHKLSHFTSIWNILDIVVILLAVVAIVFSAFRTIKVDGLLGNLLKQPDIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLTSTLARCALDIFGFAIMFFIVFFAYAQLGYLLFGTEVETFSTFNKCIFTQFRIILGDFDYDAIDRANRVLGPIYFFSYVFFVFFVLLNMFLAIINDTYSEVKSELASQKDEFQIADLIKQSYAKTFMKLKLKKEKISDVQKALDSGAS----ELEFKDFRNALKEMGHSDREISAAFSKFDQDGNQTLDKQEQENMKQELEEKRDALSAELRDLENSVEPAEEHRNTVPP----EDYQRLVHKVSQLENSVSAIMSKLDFVMEKMRLQTFNTESRDMDKQTNRD 734          

Query:  353 LRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQ-NST-----------PWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKL 1840
            +RE++IY+ FL +L+++++G     AY+ T+ +   F+T          + +    D + +    LL  LY         F +D        ++L+G  R+RQVRVR D+C I +  Q  ++ C A YS  SE   SY    N T           PW Y   + L      G +A Y GGGF V+L   Q ++   +  LF+N W+D  TRAV ++FTVYNAN+NLFC + L+ E    G     S+ + V L +  G    FV+A E ++ +FI+YY+V +   +K  K+ YF S WN+L++ +II S +     + RT+     I+    N ++  +F            LIA  + LA +K++  +  N  +  +++TL R   D++GF ++  I+F+A++    L++G ++N +  L     T+  + LG F++ ++   + + G       + F+ FV+ N+F+++I   + E  E+L    +E E      E  E++L K+
Sbjct:  617 IREILIYVGFLWMLLLVAYGQRDPNAYYLTHHIRQSFSTG--------ISETLNHKDIFIWANSSLLRNLYG----QYPGFITDG------NSKLVGNARIRQVRVRRDTCKIANPMQYSVRDCHAPYSWESEDMGSYSPGWNQTRNVNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFETTGVGTFQYRSEVQAVHLYQSTGGFHVFVMASEAIYYIFILYYMVVQGKLMKQQKWAYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMTFVVLNLFISVILVAFNE--EQLHPTPSEEE------EIVELMLMKV 1098          

Query:  188 DSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIK-----TTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQ-NST-----------PWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKL 1840
            D  EYG  + D    +N  +P++     ++   S +      D +  R   IK       +RE++IY+ FL +L+++++G     AY+ T+ +   F+T          + +    D + +    LL  LY         F +D        ++L+G  R+RQVRVR D+C I +  Q  ++ C A YS  SE   SY    N T           PW Y   + L      G +A Y GGGF V+L   Q ++   +  LF+N W+D  TRAV ++FTVYNAN+NLFC + L+ E    G     S+ + V L +  G    FV+A E ++ +FI+YY+V +   +K  K+ YF S WN+L++ +II S +     + RT+     I+    N ++  +F            LIA  + LA +K++  +  N  +  +++TL R   D++GF ++  I+F+A++    L++G ++N +  L     T+  + LG F++ ++   + + G       + F+ FV+ N+F+++I   + E  E+L    +E E      E  E++L K+
Sbjct: 1918 DQDEYGDVSIDGTL-SNTDDPDAVRIARRDSTCSFYKPPPPTDIEKMRNNMIKEQKVFALIREILIYVGFLWMLLLVAYGQRDPNAYYLTHHIRQSFSTG--------ISETLNHKDIFIWANSSLLRNLYG----QYPGFITDG------NSKLVGNARIRQVRVRRDTCKIANPMQYSVRDCHAPYSWESEDMGSYSPGWNQTRNVNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFETTGVGTFQYRSEVQAVHLYQSTGGFHVFVMASEAIYYIFILYYMVVQGKLMKQQKWAYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMTFVVLNLFISVILVAFNE--EQLHPTPSEEE------EIVELMLMKV 2458          

Query:  329 RQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYG------------QQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKL 1840
            +Q   +  + E++I++ FL++L+++++G     A++ T  +   F        S   + S   +D + +    LL  L+         F +D        ++L+G  R+RQVRV+ D+C +       + QC   YS  +E   SYG            ++  T W Y + S L      G+ A Y GGG+ ++L   + ++   +  LFN+ W+D  TRAV ++FTVYNAN++LFC + L+ E    G     S  + V L   VGS   F++A  +++ +F+VYY+  +   +K  K+ YF + WN+LD+ +II S +     I +T+     IQ    + N  P+F            ++A  + L  VK++  +  +  +  ++++L R   D++   ++ FII +A++    LIFG ++  +  L      +F + +G F++ ++  ++   G +     V    FV+ ++F++II     E +E   +Q +E E      E  E+V+ K+
Sbjct:  512 KQQKAQALVMEVLIFLGFLSMLLLVAYGQQDPNAFYLTQHIQQSF--------SKGISDSMKTNDVFVWANTVLLKNLF----GQYPGFITDG------NSKLVGNARIRQVRVKKDTCKVAKVMLHTVSQCNTPYSWGNEDMMSYGPGWEEFNSVNGSEEGITAWQYQSQSTLKALPVWGLTALYRGGGYVMDLGPDKQNATMKLQYLFNSTWLDEYTRAVFVEFTVYNANVDLFCIVTLILESSAVGAFQFRSVLQNVSLYSSVGSFMSFLMASRVIYFLFVVYYMFLQGKLLKRQKWAYFRNKWNLLDMAIIILSWSSLSLFIQKTVQGNIDIQYYQKHKNQFPSFHDTAAVDATLRYVMAFLVLLGCVKLWHLLRLSPKLYVIASSLQRAWDDMSTLTVVIFIILLAYSLACNLIFGWELYTYRTLPDAFTAIFSLQIGIFNYDEVMNSNPALGAVIISSCVLIATFVVLSLFISIILMAVTEEREN--HQPSEEE------ETVELVMMKI 1001          

Query:  281 IRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSL----------------------EEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
            +R LW TR+TE+    R+ Y+K   REL+ YI FL ++ ++++ M T   +++T  +S LF     + +  T F    T  DFWKF  GPL++GLYW  WYNN     +  +F+YYEN L+G+PRLRQ+RV+N SCS+P D + EIK C+ +YS+ +E    +G +N T W YT    L+ +   G+++ Y G G+Y++L+  + +S   I  L NNLW+DRGTRAV IDF+VYNAN+NLFC ++L+ EFP TGGL+ S QF+TVKLI Y+ S +FF+ ACE++F +FI+YYI+EE LEI +    YF S+WN LDI++I  SL     ++ +  +V+  +   +++ N+ PN ESL +WQ+QF+++ A+ +F AWVK+FK+ +FN+TMTQLS T+SRC+KD+ GFAIMFFIIF+A+AQ  YL+FG Q++DFS  Q+CI+T FRIILGDFDF ++E A+RI GP+YF  +VFF+FF+L NMFLAII DTY EVK ++A QK+E E+ D +K+     + KL LKK  + DI  ++  G     GK++FDE + +LK +G+ DAEIEA+FA+YD DGD+ L E E   M+ +LE ++  L+++       +  ++    L                           EE++ L RRVDRM+++   IV+KID V+  LE++E+ K + RE +G +L+
Sbjct:  174 VRGLWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAENH-SFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQGG----GKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 864          

Query:  248 PNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSL----------------------EEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
            P+    +F  G R LW TR+TE+    R+ Y+K   REL+ YI FL ++ ++++ M T   +++T  +S LF     + +  T F    T  DFWKF  GPL++GLYW  WYNN     +  +F+YYEN L+G+PRLRQ+RV+N SCS+P D + EIK C+ +YS+ +E    +G +N T W YT    L+ +   G+++ Y G G+Y++L+  + +S   I  L NNLW+DRGTRAV IDF+VYNAN+NLFC ++L+ EFP TGGL+ S QF+TVKLI Y+ S +FF+ ACE++F +FI+YYI+EE LEI +    YF S+WN LDI++I  SL     ++ +  +V+  +   +++ N+ PN ESL +WQ+QF+++ A+ +F AWVK+FK+ +FN+TMTQLS T+SRC+KD+ GFAIMFFIIF+A+AQ  YL+FG Q++DFS  Q+CI+T FRIILGDFDF ++E A+RI GP+YF  +VFF+FF+L NMFLAII DTY EVK ++A QK+E E+ D +K+     + KL LKK  + DI  ++  G     GK++FDE + +LK +G+ DAEIEA+FA+YD DGD+ L E E   M+ +LE ++  L+++       +  ++    L                           EE++ L RRVDRM+++   IV+KID V+  LE++E+ K + RE +G +L+
Sbjct:    2 PSPLKAKFGLGFR-LWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAENH-SFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQGG----GKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 702          

Query:  245 NPNSCW--NRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSL----------------------EEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
             P+  W  N        LW TR+TE+    R+ Y+K   REL+ YI FL ++ ++++ M T   +++T  +S LF     + +  T F    T  DFWKF  GPL++GLYW  WYNN     +  +F+YYEN L+G+PRLRQ+RV+N SCS+P D + EIK C+ +YS+ +E    +G +N T W YT    L+ +   G+++ Y G G+Y++L+  + +S   I  L NNLW+DRGTRAV IDF+VYNAN+NLFC ++L+ EFP TGGL+ S QF+TVKLI Y+ S +FF+ ACE++F +FI+YYI+EE LEI +    YF S+WN LDI++I  SL     ++ +  +V+  +   +++ N+ PN ESL +WQ+QF+++ A+ +F AWVK+FK+ +FN+TMTQLS T+SRC+KD+ GFAIMFFIIF+A+AQ  YL+FG Q++DFS  Q+CI+T FRIILGDFDF ++E A+RI GP+YF  +VFF+FF+L NMFLAII DTY EVK ++A QK+E E+ D +K+     + KL LKK  + DI  ++  G     GK++FDE + +LK +G+ DAEIEA+FA+YD DGD+ L E E   M+ +LE ++  L+++       +  ++    L                           EE++ L RRVDRM+++   IV+KID V+  LE++E+ K + RE +G +L+
Sbjct:  161 KPSLAWATNLLDMPSHRLWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAENH-SFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQGG----GKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 865          

Query:  287 SLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSL----------------------EEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
             LW TR+TE+    R+ Y+K   REL+ YI FL ++ ++++ M T   +++T  +S LF     + +  T F    T  DFWKF  GPL++GLYW  WYNN     +  +F+YYEN L+G+PRLRQ+RV+N SCS+P D + EIK C+ +YS+ +E    +G +N T W YT    L+ +   G+++ Y G G+Y++L+  + +S   I  L NNLW+DRGTRAV IDF+VYNAN+NLFC ++L+ EFP TGGL+ S QF+TVKLI Y+ S +FF+ ACE++F +FI+YYI+EE LEI +    YF S+WN LDI++I  SL     ++ +  +V+  +   +++ N+ PN ESL +WQ+QF+++ A+ +F AWVK+FK+ +FN+TMTQLS T+SRC+KD+ GFAIMFFIIF+A+AQ  YL+FG Q++DFS  Q+CI+T FRIILGDFDF ++E A+RI GP+YF  +VFF+FF+L NMFLAII DTY EVK ++A QK+E E+ D +K+     + KL LKK  + DI  ++  G     GK++FDE + +LK +G+ DAEIEA+FA+YD DGD+ L E E   M+ +LE ++  L+++       +  ++    L                           EE++ L RRVDRM+++   IV+KID V+  LE++E+ K + RE +G +L+
Sbjct:  180 GLWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAENH-SFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQGG----GKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 868          

Query:  284 RSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSL----------------------EEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
            R LW TR+TE+    R+ Y+K   REL+ YI FL ++ ++++ M T   +++T  +S LF     + +  T F    T  DFWKF  GPL++GLYW  WYNN     +  +F+YYEN L+G+PRLRQ+RV+N SCS+P D + EIK C+ +YS+ +E    +G +N T W YT    L+ +   G+++ Y G G+Y++L+  + +S   I  L NNLW+DRGTRAV IDF+VYNAN+NLFC ++L+ EFP TGGL+ S QF+TVKLI Y+ S +FF+ ACE++F +FI+YYI+EE LEI +    YF S+WN LDI++I  SL     ++ +  +V+  +   +++ N+ PN ESL +WQ+QF+++ A+ +F AWVK+FK+ +FN+TMTQLS T+SRC+KD+ GFAIMFFIIF+A+AQ  YL+FG Q++DFS  Q+CI+T FRIILGDFDF ++E A+RI GP+YF  +VFF+FF+L NMFLAII DTY EVK ++A QK+E E+ D +K+ ++  + KL LKK  + DI  ++  G     GK++FDE + +LK +G+ DAEIEA+FA+YD DGD+ L E E   M+ +LE ++  L+++       +  ++    L                           EE++ L RRVDRM+++   IV+KID V+  LE++E+ K + RE +G +L+
Sbjct:   51 RRLWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAENH-SFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKVSKA-MVKLKLKKTTVDDISESIRQGG----GKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 739          

Query:  248 PNSCW-NRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVIL----------------------PVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTL 2305
            P   W  R   G+R LW TR  E++  +R+ Y+K+ LRELV Y+FFL VL I+++GM +   Y++T  LS LF  +  +    T F   ++  DFWKF  G  L+GLYW    +N +  +D  +F++YEN L+G+PRLRQ+RVRN SCSIP D + EIK+C+  YS+SSE +  +G +N T W+YT+   L+ + + GI+A+Y G G+Y++L+ T+ ++   +  L  N W+DRGTRA  IDF+VYNANINLFC ++L+ EFP TGG++ S QF+ VKLIRYV + DFF+ ACE++F  FI+YY+VEE LEI++ +  YF S WN LD+++++ S+   + NI R    + ++Q L  + N  PNFE + +WQ+QF+N+ A+ +FL W+K+FK+I+FN+TM+QLS T+SRC+KDL GF IMF IIF+A+AQL YL+FG QV+DFS  Q CI+T FRIILGD +FA++E A+R+ GPLYF  +VFF+FF+L NMFLAII D+Y EVK +LA QK E E++D +++  +  L KL LK++ +  I  ++  G     GK++FDE + +LK +G+ DAEIEA+F +YD DGD+ L E E   M+ +LE ++  LDLE       + +++    L                        VS EE++ L RRVDRM+++   IV+KID V+  LE +E+ K + RE +G +L+ +
Sbjct:  183 PRVAWAERLVRGLRGLWGTRLMEESNANREKYLKSVLRELVTYLFFLVVLCILTYGMMSSNVYYYTRTLSQLFIDTPVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKAQTSN-HTQADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWMYTSEKELNGSSHWGIIASYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAAFIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPVKLIRYVTAFDFFLAACEIIFCFFIIYYVVEEILEIRIHRLSYFRSFWNCLDVVIVVLSVVAMVINIYRMSNAEGLLQFL-EDQNSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTIMFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFTTFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLKRNTVDAISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDLEKEREDLDLEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGV 886          

Query:  251 NSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQ-------YEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEK 2257
            +SC       IR LW T  TE+T  +R+LY+KTTLRELV+YI FL  + ++++GMT+  AY++T ++S LF  +  +D+  +F   ++ SDFW F  GPLL+ LYWT WYNN +      +F+YYEN L+G PRLRQ+RVRNDSC +  DF+ +I  C+  YS   E +  +G QN T W Y + + L  + + G + +Y GGG+Y++L  ++  S   +  L   LW+DRGTR V IDF+VYNANINLFC ++LV EFP TGG + S Q RTVKLIRYV + DFF++ CE++F VFI YY+VEE LEI + +  Y  S+WNILD++VI+ S+    F+I RTL V  ++  L+   + + +FE L FWQ Q++N+ A+ LF AW+K+FKYISFNKTMTQLS+TL+RC+KD+ GFAIMFFI+F A+AQLGYL+FG QV +FS    CI+T FRIILGDFD+  ++ A+RI GP+YFV YVFFVFFVL NMFLAII DTY EVKEELA QK++ +++D++K+     L +L L+K+++ D+Q  +  G+     ++ F+++   L+  G+ + EI A F R+D DGD  LDE EQ  M++ LE+++ +L+ EI+       +     L          VS EE+  L RRV ++      +V++ID V   L+ +E+
Sbjct:   67 SSCCLHICRSIRGLWGTTLTENTAENRELYVKTTLRELVVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTP-SDSGVSFQTISSMSDFWDFAQGPLLDSLYWTKWYNNQSLGRGSHSFIYYENLLLGAPRLRQLRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGPQNGTAWTYHSQNELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTVKLIRYVNNWDFFIVGCEVVFCVFIFYYVVEEILEIHLHRLRYLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDQLQLSDFLKQSYNKTLLRLRLRKERVSDVQKVLKGGEP----EIQFEDFTSTLRELGHEEHEITAAFTRFDQDGDHILDEEEQEQMRQGLEEERVTLNAEIENLGRSVGHSPPGELGAEAARGQSWVSGEEFDMLTRRVLQLQCVLEGVVSQIDAVGSKLKMLER 737          

Query:  311 EDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFT-TSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTS-DQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELA-NQKNEFEIADYVKERTEVVLAKLHL---XXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALE 2245
             D    R+  + TTL EL++Y  FL  L I++FGM     Y+   ++S LF  TS  +D   +F +  + ++FWKF+ GPL++GLYW +WY N    S    + +YYEN L+G+PR+RQ+RVRN++C +   FQ  +  C++ Y++ +E    +G + +  W +T SS      + G V  Y  GG+ V L+ ++ ++    + L  N WI RGTRAV IDF++YNAN+NLFC I+L+ EFP TGGLL S QF +VKL+RYV   D+F+ +CE++F +F+  +I++E  ++   K  YF S+WN L++L+++       F     +    ++  L+ N + +P+F  L +W + ++N+IAIT+F AW+K+FK+ISFN+TM+QLS+TLSRC KD+ GFAIMFFIIF A+AQLG+L+FG+QV+DFS  Q  I+  FRI+LGDF+FA ++ A+ I GP+YF+ ++FFVFFVL NMFLAII DTY EVK + +  ++ +FE+   +++    VL KL L   +  +   +Q   +A     DG   FDE            +EI+               EAEQ+   KE         LE +Y  +EI    +D   PV   +E+R L      ++     +  K++ ++  L 
Sbjct:   15 HDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHTPSSRTAPWHW-GFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFIIQELRKVNEFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGKIIQKSCFNVLEKLRLKKAQAKEEKKMQTTDLAQRARRDG---FDE------------SEIQ---------------EAEQMKRWKE--------RLEKKYYSTEI----QDDYQPVTQ-QEFRELFLYAVELEKELHYVSLKLNQLMRKLH 621          

Query:  311 EDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFT-TSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTS-DQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELA-NQKNEFEIADYVKERTEVVLAKLHL---XXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALE 2245
             D    R+  + TTL EL++Y  FL  L I++FGM     Y+   ++S LF  TS  +D   +F +  + ++FWKF+ GPL++GLYW +WY N    S    + +YYEN L+G+PR+RQ+RVRN++C +   FQ  +  C++ Y++ +E    +G + +  W +T SS      + G V  Y  GG+ V L+ ++ ++    + L  N WI RGTRAV IDF++YNAN+NLFC I+L+ EFP TGGLL S QF +VKL+RYV   D+F+ +CE++F +F+  +I++E  ++   K  YF S+WN L++L+++       F     +    ++  L+ N + +P+F  L +W + ++N+IAIT+F AW+K+FK+ISFN+TM+QLS+TLSRC KD+ GFAIMFFIIF A+AQLG+L+FG+QV+DFS  Q  I+  FRI+LGDF+FA ++ A+ I GP+YF+ ++FFVFFVL NMFLAII DTY EVK + +  ++ +FE+   +++    VL KL L   +  +   +Q   +A     DG   FDE            +EI+               EAEQ+   KE         LE +Y  +EI    +D   PV   +E+R L      ++     +  K++ ++  L 
Sbjct:   15 HDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHTPSSRTAPWHW-GFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFIIQELRKVNEFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGKIIQKSCFNVLEKLRLKKAQAKEEKKMQTTDLAQRARRDG---FDE------------SEIQ---------------EAEQMKRWKE--------RLEKKYYSTEI----QDDYQPVTQ-QEFRELFLYAVELEKELHYVSLKLNQLMRKLH 621          

Query:  353 LRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQ---------QNSTP--WVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQK-NEFEIAD 1801
            +RE++ Y+ FL +L+++++G     AY F   L   F        S  F+       F+++    L+  LY     ++  F +D        ++L+G   +RQVRVR  SC++    Q  +  C   YS+  E    YG+          N  P  W Y + S        G +  YGGGG+ V L +    +   +  LF+N W+D  TRAV ++FTVYNAN+NLFC + L  E    G        ++++L  +      FV+A EL + +F+ YY+V +   ++  K+ YF S WN+L++ +I+ S +  +  + RT+     +Q    + +   +F            +IA  + L+ VK++  +  N  M  +++ L R   D++GF  +  I+ +A++    L+FG ++  +  L     T+  + LG F++ ++     I G L     + F+ FV+ N+F+++I   + E  E+ ++Q   E EIAD
Sbjct: 1943 IREILAYLAFLWMLLLVAYGQRDPNAYHFHRHLERSF--------SQGFSPVLGFRGFFEWANTTLVKNLYG----HHPGFVTDG------NSKLVGSAHIRQVRVRESSCAVAQQLQDSLDGCHGPYSLGIEDLVDYGEGWNASAYNNSNGFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLETSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFCSKWNLLEVAIILASWSALVVFVKRTILADRDLQRYREHRDEGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSCIVFMTFVVLNLFISVILVAFSE--EQKSDQLWEEGEIAD 2417          

Query:  254 SCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQ----------YEKSEILNKTRDVILPVVSL------------EEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
            SC  R    +R LW TR   ++  +R++Y+KT LRE++ YI FL  L II++GM +   Y++T ++S LF  +  +    T F + +T  DFWKF  GP LNG+YW  WYNN +   +Q + +YYEN L+G+PRLRQ+RVRN+SCS+  D + E+  C+  YS ++E K  +G +N T W + + S L  + Y G V+TYGGGG+Y +L+ T+  S N +  L NNLW+DRGTRAV +DF++YN N+NLFC ++L+ EFP TGG + S QF+TV+L+RYV S D+FV  CE+ F +F++YY+VEE+LEI++ +  YF S+WN LD+L++  S+   I NI RT  V + +  L+ N + +PNFE L   Q+ F+NL AI +FL+WVK+FK+I+FNKTM QLS T+SRC+KDL GFAIMFFI+F+A+AQL YL+FG QVNDFS  Q CI+T FRIILGDFDF+++E A  + GP+YF  +VFF+F +L NMFLAII DTY EVK ++A Q++E EI D +K+     + KL LKK  I DI +++        GK+ FDE + +L+ +G+ DAEIEA+FA+YD DGD+ L E E   M+ +LE ++  LDLE            + +S+  ++  D      S             EE++ L RRVDRM+++   IV+KID V+  LE++E+ K + R+ +G IL+
Sbjct:  124 SCGKRILEKMRVLWDTRLLGESNSNREMYLKTVLREMITYILFLLTLCIITYGMVSTNMYYYTKVMSQLFLDTPLSSGEPTNFKSLSTMEDFWKFTEGPFLNGMYWELWYNNKSLPENQ-SLIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYDCYNVYSPANEDKAPFGPKNGTAWRFKDESSLGESSYWGQVSTYGGGGYYQDLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGAVPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFVLYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVLGPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSL----QQAAGKLSFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELTEHEHQQMRDDLEKEREDLDLEHSSLPRPASGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKMKRRDVLGRILD 823          

Query:  245 NPNSCW-NRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVIL----------------------PVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
            +P   W  R   G+R LW TR  E++  DR+ Y+K+ LREL  Y+ FL VL I+++GM +   Y++T ++S LF  +  +    T F   ++  DFWKF  G LL+GLYW T  +N    +D  +F+YYEN L+G+PR+RQ+RVRN SCSIP D + EIK+C+  YS+SSE +  +G +N T W+YT+   L+ + + G++ATY G G+Y++L+ T+ ++   +  L  N+W+DRGTRA+ IDFTVYNANINLFC I+L+ EFP TGG++ S QF+ VKLIRYV + DFF+ ACE++F +FI+YY+VEE LEI++ K  YF S WN LD+++I+ S+     NI RT  V+ ++Q L  + N  PNFE+L +WQ QF+N+ A+ +F  W+K+FK+I+FN+TM+QLS T+SRC+KDL GFAIMFFIIF+A+AQL YL+FG QV+DFS  Q CI+T FRIILGD +FA++E A+R+ GP+YF  +VFF+FF+L NMFLAII DTY EVK +LA QK E E++D +++     L KL LKK+ + DI  ++  G     GK++FDE + +LK +G+ DAEIEA+F +YD DGD+ L E E   M+ +LE ++  LDL+       + +++    L                        VS EE++ L RRVDRM+++   IV+KID V+  LE +E+ K + RE +G +L+
Sbjct:  186 HPRVAWAERLVRGLRGLWGTRLMEESSTDREKYLKSVLRELATYLLFLIVLCILTYGMMSSSVYYYTRIMSQLFLDTPVSKMEKTNFKTLSSMEDFWKFTEGALLDGLYWKTQPSN-RTEADNRSFIYYENLLLGVPRIRQLRVRNGSCSIPLDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGMIATYSGAGYYLDLSRTREETAAQVANLKKNVWLDRGTRAIFIDFTVYNANINLFCVIRLLIEFPATGGVIPSWQFQPVKLIRYVTTFDFFLAACEIIFCLFILYYVVEEILEIRIHKLHYFRSFWNCLDVVIIVLSVVAIGINIYRTSNVEALLQFL-EDQNTFPNFENLAYWQTQFNNIAAVIVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALIKLKLKKNTVDDISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEEDDDDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLD 888          

Query:  248 PNSCW-NRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVIL----------------------PVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTL 2305
            P   W  R   G+R LW TR  E++  +R+ Y+K+ LRELV Y+FFL VL I+++GM +   Y++T  LS LF  +  +    T F   ++  DFWKF  G  L+GLYW    +N +  +D  +F++YEN L+G+PRLRQ+RVRN SCSIP D + EIK+C+  YS+SSE +  +G +N T W+YT+   L+ + + GI+A+Y G G+Y++L+ T+ ++   +  L  N W+DRGTRA  IDF+VYNANINLFC ++L+ EFP TGG++ S QF+ VKLIRYV + DFF+ ACE++F  FI+YY+VEE LEI++ +  YF S WN LD+++++ S+   + NI R    + ++Q L  + N  PNFE + +WQ+QF+N+ A+ +FL W+K+FK+I+FN+TM+QLS T+SRC+KDL GF IMF IIF+A+AQL YL+FG QV+DFS  Q CI+T FRIILGD +FA++E A+R+ GPLYF  +VFF+FF+L NMFLAII D+Y EVK +LA QK E E++D +++  +  L KL LK++ +  I  ++  G     GK++FDE + +LK +G+ DAEIEA+F +YD DGD+ L E E   M+ +LE ++  LDLE       + +++    L                        VS EE++ L RRVDRM+++   IV+KID V+  LE +E+ K + RE +G +L+ +
Sbjct:  183 PRVAWAERLVRGLRGLWGTRLMEESNANREKYLKSVLRELVTYLFFLVVLCILTYGMMSSNVYYYTRTLSQLFIDTPVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKAQTSN-HTQADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWMYTSEKELNGSSHWGIIASYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAAFIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPVKLIRYVTAFDFFLAACEIIFCFFIIYYVVEEILEIRIHRLSYFRSFWNCLDVVIVVLSVVAMVINIYRMSNAEGLLQFL-EDQNSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTIMFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFTTFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLKRNTVDAISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDLEKEREDLDLEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGV 886          

Query:  248 PNSCW-NRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVIL----------------------PVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTL 2305
            P   W  R   G+R LW TR  E++  +R+ Y+K+ LRELV Y+ FL VL I+++GM +   Y++T ++S LF  +  +    T F   ++  DFWKF  G LL+GLYW    +N    +D  +F++YEN L+G+PR+RQ+RVRN SCSIP D + EIK+C+  YS+SSE +  +G +N T W+YT+   L+ + + GI+ATY G G+Y++L+ T+ ++   + +L  N+W+DRGTRA  IDF+VYNANINLFC ++L+ EFP TGG++ S QF+ +KLIRYV + DFF+ ACE++F  FI YY+VEE LEI++ K  YF S WN LD+++++ S+     NI RT  V+ ++Q L  + N  PNFE L +WQ+QF+N+ A+T+F  W+K+FK+I+FN+TM+QLS T+SRC+KDL GFAIMFFIIF+A+AQL YL+FG QV+DFS  Q CI+T FRIILGD +FA++E A+R+ GP+YF  +VFF+FF+L NMFLAII DTY EVK +LA QK E E++D +++     L KL LKK+ + DI  ++  G     GK++FDE + +LK +G+ DAEIEA+F +YD DGD+ L E E   M+ +LE ++  LDL+       + +++    L                        VS EE++ L RRVDRM+++   IV+KID V+  LE +E+ K + RE +G +L+ +
Sbjct:  185 PRVAWAERLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSN-QTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFL-EDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGV 888          

Query:  206 KSTKDSIEETNF-INPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEI---EAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPV-------VSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEK 2257
            K  +D  +ET +    +SC      GIR LW T  TE+T  +R+LYIKTTLREL++YI FL  + ++++GMT+  AY++T ++S LF  +  +D   +F A ++ +DFW F  GPLL+ LYWT WYNN +      +F+YYEN L+G+PRLRQ++VRNDSC +  DF+ +I  C+  YS   E +  +G  N T W Y +   L    + G + +Y GGG+Y++L  ++  S   +  L   LW+DRGTR V IDF+VYNANINLFC ++LV EFP TGG + S Q RTVKLIRYV + DFF++ CE++F VFI YY+VEE LE+ + +  Y  SIWNILD++VI+ S+    F+I RTL V  ++  L+   N + +FE L FWQ Q++N+ A+ LF AW+K+FKYISFNKTMTQLS+TL+RC+KD+ GFA+MFFI+F A+AQLGYL+FG QV +FS    CI+T FRIILGDFD+  ++ A+RI GP YFV YVFFVFFVL NMFLAII DTY EVKEELA QK+E +++D +K+     L +L L+K+++ D+Q  +  G+     ++ F+++   L+  G+ + EI    A F ++D DG++ LDE EQ  M+++LE+++ +L+ EI+     I++  +    P        VS EE+  L RRV +++     +V++ID V   L+ +E+
Sbjct:   51 KKPEDEPQETAYRTQVSSCCLHICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTP-SDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGEQ----EIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAVGSKLKMLER 740          

Query:   74 MQMTLGFYFKNDLLDFVFKVMHSNGDYGTRELPSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHKLNQNSVSTFQRH 2440
            MQMTLGFYFKNDLLDFVFKVMHSNGDYGTRELPSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLAGFAIMFFIIFIAFAQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPLYFVFYVFFVFFVLFNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLKKDKIIDIQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTLNSNDDNEDYDIDDDNDEIKKKKIKELIANEIHKLNQNSVSTFQRH
Sbjct:    1 MQMTLGFYFKNDLLDFVFKVMHSNGDYGTRELPSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLAGFAIMFFIIFIAFAQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPLYFVFYVFFVFFVLFNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLKKDKIIDIQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTLNSNDDNEDYDIDDDNDEIKKKKIKELIANEIHKLNQNSVSTFQRH 789          

Query:  170 PSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEK--SEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNT 2302
            P AM  + ++ GK T    +E  F N N CWN+FK GIRSLWAT+HTE+   D+ LY  TT+RELV+Y+ FL +L II+F M     ++FTN L+ LF T+ FNDNSGTF++   +SDFWKFL GPLLNGLYW  WYN+ N  +++ N++Y+EN+L+G+PR+RQ+RV+N+SC IP+  Q ++ QC+AAYS + E K+S+G QNS+ W YT  S+L +  +QG + TYGGGGFYV+L ++Q +S N I++LFNN W+DR TRAV++DFT+YNANINLFC IKLVGEFPP GG+L S +FRTVKLIRYV  +DFFVLACE+LFV++++YYI+EE +EI   K  YF S+WN+LD++V+   + C  F+I R   +Q ++  L+ N NIHPNFE L+FWQLQ+DNL A  LFLA  K+FKYISFNK MTQL +TL+ C KDL GF++MFFI+F+AFAQ GYLIFG+Q+ ++ +   CI+TLFRIIL D +F +L   + I GPLYF+ YVFFVFF+LFNMFLAI+ D YG++KEEL  ++NEFEI D++KE++  V  KLHLK++KI+D++NA+   DTNNDG MDFDEWK ELK RGY + EIE++FA++DTDGD+ LDE EQ+ M KEL DQK +L+ E+  E+   E L ++ D I P +S  +Y  L+R +D ++N   I+  K D +L+  ++I K K +SRE+  IILN 
Sbjct:   33 PCAMDGEYFDNGKITIIDYQEIGFKNEN-CWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAYGDIKEELEEKENEFEITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIES-DAIQP-ISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNA 742          

Query:  128 KVMHSNGDYGTRELPSAMSDDSYEYGKSTKDSIEETNFINP--NSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILN-KTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTL 2305
            K+  + G + T ++ + +  D+Y+   S  DS+   N  N      WNRF NG+RS+WAT+ TED K +R LYI+TTLREL IYI FLA+L+II+FGMTT   YW TNLL+ LF     N N+G+F +  + +DFW F  GPLLNGLYW +WYNN+N    +INF+Y+EN+LIGL RLRQVRV + SC I ++FQ  IK+C+  YS   ES + +G QNST W YT  + L +   QG ++TYGGGG+YV+L S Q  +++ +  LFNNLWIDRGTRAVI+DFTVYNANINLFC IKL+ EFP  GG++    F+TVKL+RYV   DFFVL CEL+++VFI+YY VEE +EIK+ K  YF S+WNILD++VI  S  C IFNI RT+ VQ I+++L+ NDN HPNF+ L+++Q  F+ L+AIT+FLAWVK+FKYISFNKTMTQLS+TL RCSKDLAGFA+MFFIIF AFAQLGYL+FG ++  F +L Y I+TL+RIILGDF F     A  IFGPLYF+ YVFFV FVLFNMFLAII DTY E+K EL NQKNEFEI DY KERT+++LAKL+LKKDK+  +QNA+   DTNNDG MDFDEWK  ++ +G+   EIE+VF+RYDTDG++ LD  EQI MQ +LE+QK +++ EI  E+SEI N +++   +  VS++EY+ LN R++ M+N    +V KI+ VL+ LE+++  K + R++M  IL  L
Sbjct:    1 KIKMAKG-WSTEDMKANVEYDAYD-EISHADSVSLDNDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVN-NTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTYGGGGYYVDLPSDQFSAFSLLNNLFNNLWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTVKLLRYVSPSDFFVLGCELIYLVFIIYYTVEEIIEIKIHKISYFKSVWNILDVVVIGISFICIIFNIYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMFFIIFFAFAQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPLYFLLYVFFVLFVLFNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMLAKLNLKKDKLDVLQNALTNADTNNDGLMDFDEWKTAMQEKGFESHEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDNSKNKRRKSMRKILTIL 726          

Query:  320 KVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILN---KTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTL 2305
            K +R LYI+TTLREL++YI FLA+L+II+FGMTT   YW+TNLLS LF   N N+N+ TF   + ++DFW F TG LLNGLYW TWYNN+N    +INF++YEN+LIGLPR+RQVR++N++C IP +F+  + QC+A+Y MS ES DS+G QNST W YT+ SVL +  +QG ++TY GGGFY++L   Q  +   +  L+ NLWIDRGTRAVIIDFTVYNANINLFC IKLV EFP  GG++ +  FRT+KLIRYVG  D+F+L CEL +++F++YY +EE +EIK+ K  YF S+WN LD++VI  S  C IFNI RT+ VQ I+  L+ N N HPNF++L++ Q  F+ L+A+T+FLAWVK+FKYISFNKTMTQLS TL RCSKDLAGFA+MFFIIF AFAQLGYL+FGAQ+  F +L Y I+TL+RIILGDF F+  +  H I GPLYF+ YVFFVFFVLFNMFLAII DTY EVK ELAN KNEFEI DY KERT  +L KL+LKK+KI DIQNA+   DTNNDG MDF+EWK  +K RG+ ++EIE VF++YDTDG++ LD+ EQI MQ++LE+ K  ++ EI  E++E+ +     +  ++  VS++EY  LN RV+ M+NN   +V+KID VL  LE+++K KA+ R+ MG ILNTL
Sbjct:   21 KGNRDLYIQTTLRELILYIIFLAILMIIAFGMTTGTMYWYTNLLSNLFLNGNGNNNTNTFLTMSADADFWNFATGALLNGLYWNTWYNNLNLDPSEINFIFYENKLIGLPRMRQVRMKNNTCIIPLEFKNIVNQCYASYKMSDESTDSFGLQNSTAWNYTSGSVLGSYPFQGTISTYSGGGFYIDLPIDQPTALGVLNFLYTNLWIDRGTRAVIIDFTVYNANINLFCVIKLVAEFPAVGGVIPTYDFRTIKLIRYVGPFDYFILGCELAYLIFLIYYTIEELIEIKINKMSYFHSVWNCLDVIVISISFVCVIFNIYRTIAVQTILGDLLMNSNQHPNFDNLSYNQTTFNYLLAVTVFLAWVKIFKYISFNKTMTQLSTTLGRCSKDLAGFAVMFFIIFFAFAQLGYLLFGAQLQSFRELHYSIFTLYRIILGDFTFSDFQTVHIILGPLYFILYVFFVFFVLFNMFLAIINDTYSEVKNELANVKNEFEIGDYFKERTIKMLEKLNLKKEKIADIQNAITNADTNNDGLMDFEEWKAAMKVRGFEESEIENVFSKYDTDGNRVLDQTEQIEMQRQLENLKAEVNNEIMVEQAELTDCDLGLKKGVIRGVSIDEYNILNSRVEEMENNIISMVSKIDMVLRNLENMDKAKAKRRKAMGKILNTL 685          

Query:  161 RELPSAMSDDSYEYGKS-TKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFT-SDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPV------------------------VSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTL 2305
            +E  +  SD+ +E+    T+  +EE +      CW RFK G+R++W T  TEDT+ DR+LYIKTTLREL++Y+FFL VL++++FGMT+   Y+FT+++   F  +  ++   TF+ +TT +D+W+F+ GPLL GLY T WYNN+NF+ S ++NF+YYEN+L+G+PRLRQV+VRNDSCSI  DF+ EIK C+A YS   E K  +G  NST W +T    LD   Y G +A+Y GGG+YV+L   + DS   I  LF  LWIDRGTR   +DFTVYNANINLFC +KLV EFP TGG + SS++RTVKL+RYV   D+ VL CE++F++FI YY+VEE +EIK  K  YF S WN LDILVII SL C+ FN+ RT+ V N +  L+ +++  P+F+ L++WQLQF+N IAIT+F AWVK+FKYISFNKTMTQLS+TL  C+KDL GFA+MFFIIF AFAQLGYLIFG QV DF + Q  I+TLFRIILGDFDF +LE AHR+ GP++F+ YVFFVFFVL NMFLAII DTY EVK +LANQ N+FE+ DY KER   V+ KL++K+DKIIDIQ A+ + D NND ++DF+EW+ ELK RGY D EIEA+FA+YD DGD+ LDE EQ  M  ELE QK +L+ +IQ E+    +      L                          VS EE+  L RRVDRM+++   IV+KID VL  L+++EK K R RETM  +L+++
Sbjct:   50 QEPEACQSDNPFEHPDGQTEPEVEEAH-----GCWFRFKRGVRAIWRTNMTEDTREDRELYIKTTLRELIVYLFFLIVLMVLAFGMTSSTMYYFTSVMQAQFDQAPNSETQTTFSTATTIADWWRFVKGPLLEGLYVTNWYNNLNFSDSREVNFVYYENKLLGVPRLRQVKVRNDSCSIADDFKNEIKACYAMYSPGVEEKSPFGYMNSTAWNHTTEKELDGRSYAGQIASYDGGGYYVDLTRNRDDSAAIIEELFKGLWIDRGTRVAFVDFTVYNANINLFCVVKLVMEFPATGGAIPSSEYRTVKLLRYVEPRDYVVLICEIIFMLFICYYVVEEVIEIKRHKLGYFKSFWNWLDILVIIISLVCAGFNVYRTIAVGNKLTELLKDESKFPDFDFLSYWQLQFNNAIAITVFFAWVKIFKYISFNKTMTQLSSTLGACAKDLVGFAVMFFIIFFAFAQLGYLIFGTQVKDFREFQQAIFTLFRIILGDFDFHELENAHRVLGPIFFLLYVFFVFFVLINMFLAIINDTYSEVKSDLANQPNDFEMTDYFKERAGKVMDKLNIKRDKIIDIQKAMQSADVNNDRQLDFEEWRAELKMRGYADGEIEAMFAKYDVDGDRVLDEEEQRRMTSELEGQKAALNDQIQSERDRPASARSTADLGADADDRLRSSRRGVSGGGGGGGGAGVSSEEFTVLARRVDRMEHSIGSIVSKIDAVLVKLDTMEKAKLRRRETMSKLLDSI 785          

Query:  263 NRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFND-NSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKT----------------------RDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
             R    +R LW TR  ED++  R++Y+K  LRE V YIFFL  L II++GM +   Y++T ++S LF  +  +  +  TF   +T  DFWK+  GP LNG+YW  WYNN +   +Q + +YYEN L+G+PRLRQV+V N SC +  D + E+  C++ YS +SE K  +G +N+T WVY+  ++L  + Y G VATY GGG+Y +L  ++ +S   +  L +NLW+DRGTRAV +DF+VYN N+NLFC ++++ EFP TGG + S QF+TV+L+RYV S D+FV  CE++F +F++YY+VEE LEI++ +  YF S+WN LD++++  S    I NI RT  V N ++ L+ N + +PNF+ L   Q+QF++L A+ +FLAWVK+FK+I+FNKTM+QLS T+SRC+KDL GFAIMFFI+F+A+AQL YL+FG Q+NDFS  Q CI+T FRIILGDFDF+++E  +R+ GP+YF  +VFF+F +L NMFLAII DTY EVK ++A Q++E EI D +K+  +  + KL L+K  + DI +++        GK++FDE + +L+ +G+ DAEIEA+FA+YD DGD+ L E E   M+ +LE ++  LDLE       +  ++                      R      VS EE++ L RRVDRM+++   IV+KID V+  LE++E+ K + RE +G +L+
Sbjct:  130 KRILAKLRILWGTRLMEDSESSREVYLKNVLRETVTYIFFLITLCIITYGMVSTNMYFYTKVMSQLFLDTPLSKGDPTTFKTLSTMEDFWKYTEGPFLNGMYWDVWYNNKSLPENQ-SLIYYENLLLGVPRLRQVKVLNKSCPVHEDLKDEVYDCYSIYSPASEDKAPFGLKNNTAWVYSEENILGESSYWGEVATYRGGGYYQDLARSREESARQLKELKDNLWLDRGTRAVFLDFSVYNGNVNLFCIVRMLVEFPATGGAVTSWQFQTVRLVRYVSSWDYFVGTCEVVFCLFVLYYMVEEVLEIRLHRLRYFKSLWNCLDVIIVTLSAPAIIMNIYRTSAVSNRLRYLLENHSTYPNFQPLAQVQVQFNHLAAVIVFLAWVKLFKFINFNKTMSQLSTTMSRCAKDLLGFAIMFFIVFLAYAQLAYLVFGNQLNDFSTFQACIFTQFRIILGDFDFSEIEETNRVLGPIYFTTFVFFMFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKGYQKAMVKLRLRKTTVDDISDSL----RQAGGKLNFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELSEHEHQQMKDDLEKEREDLDLERSSLPRPMSGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 826          

Query:  251 NSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLE-----IQYEK----SEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMG 2287
            + C +    GI+ LW T  T+DT  +R+L+++TTLRELV+YI FL  + ++++GMT+   Y++T +++ LF  +  +D+  TF +  T  DFW +  GPLL+GLYWT+WYNN +  +   +F+YYEN L+G+PR+RQ++V+N SC +  DF+ EI  CF  Y+   E   S+G  N T W Y     L  + + G++ATY GGG+Y +L  T+ +S   +  L NNLW+D GTRAV IDF+ YNANINLFC I+LV EFP TGG + S Q RTVKLIRY+ + D+F++ CE++F VFI+YYIVEE LE+++ K  YF SIWNILD+++I+ ++   +FN+ RT+ V  ++  L+   +I+ +FE L FWQ Q++N+ A+ LF AW+K+FKYISFNKTMTQLS+TL+RC+ D+ GFAIMFFI+F A+AQLGYL+FG +V  FS    CI+T FRIILGDFD+  +E A+R+ GP+YF  YVFFVFFVL NMFLAII DTY EVKEELA+QK++ +I D +K+       KL LKK+KI D+Q  + +G      +++F +++  LK  G+ D EI A F+++D DG++ LD+ EQ  M++ELE+++++L +E     I YEK    ++   KT  V+   V+ ++++ L ++V  ++ +    + KID V+E L   +  K   ++  G
Sbjct:   86 SGCCSFLLRGIKGLWGTTLTKDTTENRELFVRTTLRELVVYIVFLVDMCLLTYGMTSSTTYYYTKVMTDLFVNAP-SDSGVTFQSIGTMDDFWSYAQGPLLDGLYWTSWYNNQSLQTGTHSFIYYENMLLGVPRVRQLKVKNKSCKVHKDFEEEISDCFDVYNEKKEDDSSFGLINGTAWQYHTEKELKGSNHWGMLATYSGGGYYQDLALTKEESAGVLANLNNNLWLDHGTRAVFIDFSTYNANINLFCVIRLVVEFPATGGAIPSYQIRTVKLIRYITTWDYFIIGCEIVFCVFILYYIVEEILELRIHKLSYFKSIWNILDVVIIMLAIVAIVFNVFRTIKVDKLLGNLLKEPSIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCATDILGFAIMFFIVFFAYAQLGYLLFGTEVESFSTFHKCIFTQFRIILGDFDYDGIERANRVLGPIYFFTYVFFVFFVLLNMFLAIINDTYSEVKEELASQKDDLQITDLIKQSYSKTFMKLKLKKEKISDVQKVLRSGSK----ELEFKDFRETLKEMGHADHEISAAFSKFDYDGNQILDKEEQETMKQELEEKRDALSVELHNLGINYEKNGKETDDNEKTNSVL---VTAQQFQMLVKQVVELECSLATTMAKIDVVMEKLGLQDAGKTNKKDATG 765          

Query:  353 LRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYEN-RLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYG------------QQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFE 1792
            +RE++IY+ FL +L+++++G     A++ T  +   F        S   + S T  + +++    LLN L+             Q  F+   N +L+G  RLRQVRV++ SC +    +  +  C A YS   E   SYG            +   TPW Y   S L      G VA Y GGGF V+L   + ++ +++  LF N W+D  TRA+ ++FTVYNAN+NLFC + L+ E    G     S+ ++V+L +  G +  FV+A E+++ +FI YY+ ++   +K  K+EYF S WN+LD+ +II S +     I RTL     I+    + + +  F            +IA  + LA VK++  +  N  +  +++TL R   D++GF ++  I+F+A++    L++G ++  +  L     T+  + LG F++ ++   + + G       + F+ FV+ N+F+++I   + E  E++ ++ +E E
Sbjct: 2090 IREILIYMGFLWMLLLVAYGQRDPNAFYLTQHIQQSF--------SNGISDSMTHGEVFQWANSTLLNNLF-----------GQQPGFITDGNSKLVGNARLRQVRVQDGSCRVDRSMRNSVPDCHAPYSWDMEDLGSYGPGWNPSIDANLSKTLPTPWQYQTQSRLRAHPIWGGVAVYRGGGFVVDLGPNRENASSSLQYLFENTWLDMFTRAIFVEFTVYNANVNLFCIVTLMFETTAVGAFQYRSELQSVRLYQSTGGLHIFVMASEVVYFLFIFYYMFQQGKLMKQQKWEYFRSKWNLLDMAIIILSWSALPVFIKRTLLGNQSIEYYQNHKDEYAGFNETATADAVLGYIIAFLVLLATVKLWHLLRLNPKLHMITSTLQRAWNDISGFIVVMTIMFLAYSVACNLLYGWKLYSYRTLLNAAQTIVSLQLGIFNYEEVLDYNPVLGAFIVGSCIIFMTFVVLNLFISVILVAFSE--EQIHHKPSEEE 2561          

Query:  272 KNGIRSLWATRHTEDTKVDRQLYIK-----TTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNS------------TPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIAD 1801
            +N   S +      D    ++++IK       + E++IY+ F  +L++ ++      A++ T  +   F        S   + S ++ D + +    LL  L+    Y+   F +D        ++L+G  RLRQVRV+  SC   S  +  +  C A YS   E   SYG   +            TPW Y   S L      G +A Y GGGF V+L   Q +S + +  LF N W+D  TRA+ I+FTVYNAN+NLFC + L+ E    G     ++ + ++L +    I    L  E ++ +FI+YY+  ++  +K  K+EYF + WNIL++ +I+ S +     I + +     ++    + N  P+F            L A+ + LA +K++  +  N  +  ++ TL +   D++ F ++  I+F+A++ +  L+FG ++  +  L      +  + LG F++ ++   + + G       + F+ FV+ N+F+++I + + + +      + E EI D
Sbjct: 1177 RNSSCSFYQPPPPSDVGKMKEIWIKDQKAFALIWEILIYLGFFCMLLMAAYSQRDPNAFFLTRHIQQSF--------SNGISDSMSQQDVFIWANSSLLTNLFGQ--YSG--FITDG------NSKLVGTARLRQVRVQKSSCRKASSVRSSVPDCHAPYSWEVEDMGSYGPGWTSLIDSNMSKALFTPWQYQTQSRLRAHTVWGGMALYRGGGFVVDLEPDQQNSSSVLQYLFENAWLDIYTRALFIEFTVYNANVNLFCIVTLMLETTAVGAFQYRTELQNIRLFQTTDGIP--TLVSEAIYFLFILYYMFLQAKLMKQQKWEYFRNKWNILELAIILLSWSAFSVFIKKMVQGDQDLKYYQDHRNQFPSFYETAAADSVLGYLTAVLVLLATIKMWHLMRLNSKLNMITNTLQQAWSDISSFIVVIVIMFLAYSIVSNLLFGWKLYTYKTLIDAATAMVSLQLGIFNYEEILDLNPVLGAFIIGSCIIFMTFVVLNLFISVILEAFSQEQRHHKPSEEE-EIVD 1682          

Query:  857 GGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQY-CIYTL 1603
            GGF   L+    DS + I  L ++ W    TRA+ ++F++YN N +L     L+ EFP +     S   +T  L   +       L   LL ++FI+Y+ V E +        YF  +WN+  +  ++ +   S  ++ R+     +  + +       +F  L         L A  LFL  +K    + F +       TL R   +L   A+   ++ +A++ +G+L+F + +  ++ +   C+Y L
Sbjct: 3727 GGFVQELSRRMEDSRSLIQQLLSHQW----TRALFVEFSLYNTNTDLLAVFTLLLEFPVSERAQSSLDLKTCSL-HTLHHGLDLSLFLTLLLMIFIIYFSVREGVAAHRQGRSYFLRVWNLAGMCTLLLAAVVSALHLSRSALATRLWASFLQQRESFTDFFPLAQQNQVLTQLNATLLFLLVLKASHQLRFLREWAVFGRTLRRSVWELLAAALALLVLLLAYSHMGHLLFHSVLEGYATVSSACLYLL 3971          

Query:  146 GDYGT-RELPSAMSDDSYE-YGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDN-SGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXX--XXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILN----KTRDVILPVVS------------------LEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEK 2257
            GDY   + LP +  D S   Y +  +D   +             K+ +R LW TR TED   DR  Y+KTTLREL +YI FL  L+I++FGMT+   Y +T  +  LF  +  + N S  F +  T  DFWK + GP+LNGLYW  WYN+I    +Q +F+YYEN L+G+PR+RQ++VRNDSC++ +DFQ +++ C+AAYS  +E K S+G    TPW Y+ SS ++ + + G++ATY GGG+Y++L  ++ +S   +  LF+  W+DRGTRA++IDF+ YN NINLF  I+L+ EFPPTGG + SSQ  TVKLIRYV   D+F+LACE +F  FI+YYIVEE LE+ + KF YF S+WN LD+LVI+ S+   IFN+ RT+TV  +++ L+   N + NF+ L FWQ Q++N++A+ +F  W+K FKY+SFNKTMTQLS+TL+RC+KD+ GFA+MFFIIF A+AQLGYL+FG QV DFS    CI+T FRIILGDFDF  +E A+R+ GPLYF  YVF V    +  NMFLAII DTY EVK ELA ++NEF++  Y K+    +  KL   +  I+D+ + + A       K+++D+W+++LK  G+ D EIEA FA++D D +  LD  E   M+ EL+ QK    ++       +LN    +  D     ++                     Y+ L + VD ++ +   + +K+D ++  + S+ K
Sbjct:   47 GDYPKGKPLPGSYVDSSSAVYEEIPEDGPHKAEEDQSGGPKKSRKSVLRGLWGTRLTEDI-TDRDKYVKTTLRELFVYIAFLINLIILTFGMTSDLMYKYTLAMDNLFLQNTVSPNDSVNFNSIFTFDDFWKVVQGPVLNGLYWEKWYNDIPLVENQ-SFIYYENFLLGVPRIRQLKVRNDSCTVHADFQKDVQGCYAAYSEDAEDKASFGPATGTPWKYSTSSDMNGSSHWGLLATYSGGGYYLDLTRSKSESAILLQDLFDKQWLDRGTRAILIDFSSYNGNINLFSVIRLLVEFPPTGGAVPSSQIYTVKLIRYVTGSDYFILACEGIFCCFILYYIVEEILELSIHKFAYFKSVWNCLDLLVIMLSVVAIIFNVYRTVTVNKLLKALLDEPNRYGNFQFLAFWQTQYNNMVAVNVFFCWIKFFKYVSFNKTMTQLSSTLARCAKDVLGFAVMFFIIFFAYAQLGYLLFGTQVEDFSTFSNCIFTQFRIILGDFDFNAIENANRVLGPLYFTTYVFVVFFVLLPKNMFLAIINDTYAEVKNELAEKENEFDVGGYFKKVYLDIRKKLGKNRGNIVDMISVLDASSQ----KINYDDWRLKLKRLGHSDEEIEAAFAKFDKDKNSVLDSNEMKLMRDELKSQKKDGSMDRVLSPCVLLNYVIFRNLDCSAKCINNLSGEINHRRYADDISTLYNVYKRLVQNVDNLEQSISTMFSKVDVIMNKVGSLAK 771          

Query:  287 SLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGT-FAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGK-MDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALE 2245
              W TR TE     R+ Y KTTLREL+IY+ FL  L +++FGM     Y++T ++  LF  S  +   GT F + ++  DFWK + GP+L+GLYW  WYN      + ++F+ YEN ++G+PR+RQ++VRN SC+I   F+  I  C+  YS   E K+++G+   T W Y +   L  + + G++A Y G G+Y +L+  + +S   +  L + LW+D GTRAV IDFT YN NINLFC ++LV EFP TGG L S QFRTVKLIRYV + D+F++ACE++F  FI+YY+VEE LE+++   +YF S+WN LDI+VI+ S+   IFNI RT+ V N++  L+ + NI+ +FE L FWQ QF+N++AI +F AW+K+FKY+SFNKT+TQLS+TL+RC+KD+ GFA+MFFIIF A+AQ GYL+FG+QV DFS    CI+T FRIILGDFDF  +E A+RI GP+YF  Y+FFVFFVL NMFLAII DTY +VK ELA+ K++FEI D+ K+  + +L KL +KKD I D+Q A+     ++ GK +++D W+  L   G+ D EI A F+++D D D  LDE EQ  ++ ELE QK+ L+ +I+  K+ + N  +      V+ +++     RV +M+++   +++K++++L  LE
Sbjct:   10 GFWGTRLTE-VNSTREQYFKTTLRELIIYVVFLIDLCLLTFGMMNTNTYYYTKVMMDLFVESPVSPIDGTNFNSISSMDDFWKVVQGPVLDGLYWEKWYNGDQLPVN-LSFIQYENVMLGVPRVRQLKVRNGSCTIYPLFRNIIPGCYDGYSCGEEDKETFGRGTGTAWKYWSEEELSGSSHWGLLAQYSGAGYYRDLSRRKNESAPMLQELKDYLWLDHGTRAVFIDFTTYNGNINLFCVVRLVVEFPLTGGALPSYQFRTVKLIRYVSAFDYFIMACEVIFCCFILYYVVEECLELRLHGMKYFKSVWNCLDIIVIVLSMVAIIFNICRTIAVSNLLGALLNDPNIYADFEYLAFWQTQFNNMLAINVFFAWIKIFKYVSFNKTLTQLSSTLARCAKDVLGFAVMFFIIFFAYAQTGYLVFGSQVEDFSSFVNCIFTQFRIILGDFDFHAIENANRILGPIYFTTYIFFVFFVLLNMFLAIINDTYTDVKAELADTKDDFEIGDFFKQGYKNMLNKLKMKKDDIADMQRAL-----DSAGKHLEYDIWRKNLIRLGHSDEEIAAAFSKFDKDSDNVLDEDEQKQLRAELEGQKDKLNEDIEALKT-MDNSGKPGDASRVTKDDFNRFASRVAKMESSMDSLMSKVESLLTKLE 656          

Query:  290 LWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNF-NDNSGTFAASTTESDFWK----FLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSC-SIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNS-TQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLA-CELLFVVFIVYYIVEESLEIKMLKFEYFFS-IWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIH-PNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTR------------------------------DVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTL 2305
            LWATR TE   ++R+ Y+K  +RE V +  FLA+L ++++      AY +T+ +S +FT+S   N +  TF    T    W+    +LTGPLL  L+ +    + N T+  ++    EN ++    + Q RV N+SC S+ ++      +C+  YS ++E+KD +G  NST W + + +      +QG +  YG GG+ V L + ++  ++  +  L +  W+DR TR + +D  + N N+ L+  ++L  EFPPTGG+L +    ++   R +G+  +   A C LL  +  +YY+VEE LE++ L    F S  W  LDI +I   +  + F +   +   +++    ++  +      ++  W+  F  +  + +F+AW+KV ++ S  +T+T     L+RC+ DL G+ ++F  +F+AFAQL +LIFG  + DFS    CI T  RI+LGDFDF+ LE A RI GP+YFV YVF V  ++  MFLAI+++ Y E K E A+ + +F+++  +K+    V+ +L  KK ++  IQ  +        G+++F  W+  LK +G+ DAEIEAVFARY  DGD AL  AEQ+ M+++L  +K ++ L I     E   K +                                    VS EE+R L RRV++M+++   +V+K+D V+  LE++E+ + R R+ +  +++ +
Sbjct:    2 LWATRWTESPVLNRERYVKLAIREAVTFSVFLALLCVVAYSSRIPLAYEYTHAVSEMFTSSPLSNADPTTFHNLATIEQVWQVFHGYLTGPLLWALHNS---GSRNLTNSMVS---GENLVVEPVIIWQARVHNNSCWSLSTNLGTGTTECYGPYSSANENKDPFGPANSTVWRFDSEA---GVPWQGALGWYGPGGYAVRLPADSRTAAWQELAALRDASWLDRATRLLSVDAALLNPNLRLYMVVRLSMEFPPTGGILTA---LSLTPGRPLGTPLWDARAVCGLLAALLTIYYLVEEVLELRNLGPAGFLSSPWTFLDISIIALCVVGTAFGVHHGILSSSLLGEASSSRAMSFSTVSTVAEWEQNFIIVTGVIVFVAWIKVVRFGSMCRTLTMCGCALTRCAWDLLGYTLVFATVFLAFAQLAFLIFGGALPDFSSFSSCILTQVRILLGDFDFSSLEAASRIMGPIYFVSYVFCVGLIMMVMFLAIVSEAYSEEKSEQAHSQPQFQLSSVIKQVK--VVDRLSCKKPRVAGIQKTL-----PPSGQINFATWRQNLKGQGFADAEIEAVFARY--DGDGALTRAEQLQMRRDLRLEKQTIRLHISVSPREKKKKHQVTSRDDDDDDDDGDSDEDDDITVVRRGNHHQGGGGGVSREEFRVLVRRVNQMEHSIGSVVSKMDAVMVKLEAMERQRLRRRDVLSRLISGM 692          

Query:  353 LRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLY-YENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQ--------------GIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTV-KLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTY 1747
            +R+L++++   A+LV I++      A+   N +   F  ++F+ N                     L   Y   WYN    +  +  +L  +    +G  RLRQ+R      S+P  +   +    A  ++S        + N      T        +YQ                +A Y GGGF   L     D    +  L +  W+D  TRAV+ +FT YN N +LFC + L+ EF    G      +  V ++  +VG ++       ++F + +V     E+L +  L   YF S WNI ++L I       +   ++       ++    + +   NF+ L  W  Q   L+A  +F++ +KV  ++   +    L    S     + GFA++  ++F +F QL  L+F   + ++     C+  LF ++LG   + +L  A+R+ GPL +  +     FV+ N  L I+++ +
Sbjct:  612 VRQLILFLMHAALLVFITYRGRDPYAFLVQNSVRNAFVLNSFDHNG-------------------FLPNFYPRAWYNGERMSWRERYYLRDFSTIRVGPGRLRQIR------SVPRAWNLLLSAPTAVATLSRAPYVVAARANQRCGEGTTQRKRAVRQYQIFSHRVTQLVPVWHPSLALYSGGGFIAELGLNLADGTEIVANLSSASWLDHSTRAVLTEFTGYNMNTDLFCSVTLLLEFSQGAGDAHGHAYIHVFRIESFVGKLETLTGVVYIVFAILLVIIAATEALRLSELGVAYFKSFWNIAELLSITLGAASVVTYFIKMSVATRTLEKFRTDPHKFVNFQELVTWDQQLSELLATLVFVSTIKVLGHMKSLRQFEVLVGAFSEARDHIQGFAVIVVVVFCSFGQLTSLLFAGSLRNYRTFTTCLEQLFSLLLGQPGYGELYAANRVLGPLIYFAFTSVNTFVIVNFSLGILSEGF 1067          

Query:  833 GIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVL--ACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNI--HPNF------------ESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTY 1747
            G + T+ G G+  +L  T  ++   +  L  N W+D  T  +   F +YNAN NLFC ++++ E         SS  +  +L      I + +L     + +++  +Y++      I   KFEY     N+ +I+ I             TL +  +I+ +  +  +  H NF            + L     QF  L+   LFLA +++     +N TM++     + C+  L  F+++FF++ I+++ + + + G +V  +      + +LF  + G   F  L  A      L +  ++     +L NM + +I + Y
Sbjct:    1 GELNTFIGSGYIADLGLTFAEASGNMSYLEQNSWVDARTTGLYAQFIIYNANANLFCLVEVLVESLSADMFQPSSNLKVFRLFN--NRISYIILDNVAYIFYLIISMYFLTCVIFSITKEKFEYLKKPMNVAEIMNI-------------TLMIMKLIKQVSRSPALGSHLNFFFLINYCTLYSHKPLILLSTQFLGLV---LFLATLRILPLFRYNTTMSEAVTLAAHCAHKLCSFSLIFFVLLISYSLIFWNVLGTRVGAYRSFGKSVGSLFAALHGAPVFGDLYAAGGYMAALLYFSFMLLFTVLLLNMMVVVIEEVY 303          

Query:  167 LPSAMSDDSYEYGKSTKDSIEETNFIN-PNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTS--DQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDV--------------------------------------ILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTL 2305
            +PSAM  +   + K     +      N P  CW RFK  IR LW TR TEDT  DR+++IKTTLREL+IY+ F+ +L I++FGMT+   Y+FT ++  LF  S+ + N  TF   TT ++FW + T  L +GLYW  +YNN N T   D + F+Y+EN+++G PR RQ+RV NDSC++  DF+  IK+C+AAYS + E  +++G+ N + W Y     L    Y G + TY GGGF   L  T+ ++   I  L  NLW+DRGTRAV IDFTVYNANINLFC ++LV E+PPTGG + S  FRTVKLIRYV + D FV+ACE +F++FI+YY +EE LEIK  K +YF S WN+LD++VI+      +FN+ RT+ V +++ +L+ + + + NF+SL FWQ QF+N++A+ +F AW+KVFKYISFNKTMTQLS+TLS+C+KD+AGFAIMFFIIF A+AQLGYLIFG QV DFS  +  I+TLFRIILGDFDF Q+E A+R+ GPL+F+ YVFFVFFVL NMFLAII DTY EVK ++A+Q++EFEI DY K+  + +L KL  K++KI+DIQ A+ + D N D K+DF+EW+  LKSRG+ DAEIEAVFA+YD DGD+ LDE EQ  MQ++LE QK  L+ EI+  + +  ++ +                                            VS EE+  L+RRVDRM+++   IV+KID VL  LE++EK K + RETM  +L+++
Sbjct:   53 MPSAMEAEPVSHQKRIAADVRVPGAKNVPVGCWTRFKRIIRGLWRTRQTEDTDSDREMHIKTTLRELIIYLVFITILCILTFGMTSSTMYYFTKVMRDLFVESSMS-NRNTFKDITTMNEFWMYTTETLSDGLYWEQYYNNQNVTKPKDDLGFIYFENKILGRPRFRQLRVLNDSCTVHDDFKSVIKECYAAYSPNVEDMNTFGKMNGSAWTYQTEKDLQGRSYWGRMTTYSGGGFTQLLAPTKAETQQIIEDLKQNLWLDRGTRAVFIDFTVYNANINLFCIVRLVFEYPPTGGCIPSFNFRTVKLIRYVDTFDHFVMACEGIFILFIIYYTIEEGLEIKKHKMKYFKSFWNVLDVVVIMLGYVAVVFNLYRTMAVGDLLSSLLEDGSQYANFDSLGFWQTQFNNMVAVAVFFAWIKVFKYISFNKTMTQLSSTLSKCAKDVAGFAIMFFIIFFAYAQLGYLIFGTQVRDFSTFEDSIFTLFRIILGDFDFHQIENANRVLGPLFFMTYVFFVFFVLLNMFLAIINDTYAEVKSDIASQESEFEITDYFKKGYQNMLNKLSFKREKILDIQKALKSADVNQDNKLDFEEWRANLKSRGHADAEIEAVFAKYDLDGDRILDEDEQRRMQEDLEGQKAELNDEIEEMERQKESRPKSASRMSFRGSDADSDDDDDDSQGGLSGRVGSAAGHRRGGGGGGGVSYEEFNVLSRRVDRMEHSIGSIVSKIDAVLVKLEAMEKAKLKRRETMAKLLDSI 805          

Query:  326 DRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLF--TTSNFNDNSG---TFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQ------------NSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLA 1834
            D++  +   L ++  Y+ FL VL++I+       AYW +  +S +   TT      SG   TF   + +S+ W +    LL  LY   WY         +        ++G  R RQ+R + D+C I    +G I  C   YSMS++ + +Y  +             ST W + ++S L+   Y G ++TY GGG+ V  +S    +   I    NN WIDR T  +  +FT+YN   NLF    ++ E  PTGG  V  +F T +L   VG    F L C+++F++F  Y+   E  ++   K  YF   WN  +I++++ +        +     +  ++    N N + NF+ ++ WQ+ F++++ I +F++ +K  K + FNK M  L+ TLSR +KDLA + IMF I+F++FAQ  YL+ G+  + FS     I  L  ++LG F F +  +  RI G   F  Y+    F+L NMF+AII +++ EVK      +NEFEI ++  ER   VL 
Sbjct:  543 DKERKMSVILTDIGTYLTFLWVLLVIAHSRVDSAAYWQSRSISDVLMKTTYESPPESGLTKTFQKISNDSEIWLWTNHVLLPALYNLDWYYYTKTAPKLVR--GGAGLVVGFARWRQLRKKKDTCLITGVMRGVIHHCTDPYSMSTQDETNYNSRWRPFNTSDVPPSPSTIWSFNSASKLNGYPYFGEISTYSGGGYIVPFSSIYYKAVKEIKHARNNSWIDRYTAGLFTEFTLYNPYSNLFTASTVLVEVLPTGGFHVRPEFFTFRLYSLVGDFHIFTLVCDVVFLLFTSYFTFRELKKLYKDKCSYFRDYWNWAEIVIMVLAWIAVADYFICLGIRKWTLKLHQENPNDYTNFQYISAWQMSFESILGILVFISTIKFIKLLRFNKKMFLLAYTLSRSAKDLAHYGIMFLIVFLSFAQFYYLLLGSDYDSFSTFVKSIEKLINVLLGRFSFEEFLIPFRIMGAFGFFLYMTLTNFLLLNMFIAIIVESFTEVKLSPELARNEFEIMEFTVERVREVLG 1060          

Query:  326 DRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYN----NINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSY---GQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNL----WIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYV 1807
            +RQ+   + +RE+V Y+ FL +++ IS+G         TN +  +F  +++N  S  F    +  D+W +L   ++  ++   WYN    ++ + +D          ++ + RLRQ+R++  +C +    Q  I  C   YS   E +       ++  T W Y     L T  Y G  ATY  GG+      +   +Y+    L + L    W+D+ TRAV  +F++YNAN NLFC + L+ E  PTGG+       T++L RYVG   FFV ACE+++++F  Y+I  E  +   L  +   + W+IL+I V   SL+  +   +R      +++ +  +     +     F       L+ + +F +++K+ + + FN+ M+ L+ TL  C   +  F I++ I F A+AQL  L+FG     F  +     TL   +LG F   ++   +R+ GP +F  Y   + F+L NMF++II D++ EV  +++ Q N++EI D++
Sbjct:    2 ERQM--ASIMREIVWYLIFLFIVLSISYGNRDPYTQLVTNNVENVFLQASYN-GSTKFDEIGSTRDYWPWLKDTVIPSIFIEKWYNDQDYHLGYLADTPT-----AWVLAVARLRQLRMQKHTCPLLPALQHVIPSCNDFYSSDEEERGMLLPGWKEPKTAWQYQTGEELKTFPYWGQKATYSAGGYVQVFPPSTAKNYDKAQALADALNENDWLDKYTRAVFTEFSIYNANSNLFCVVTLLIEQLPTGGIFKFPSILTLRLYRYVGGEMFFVAACEIIYLLFTAYFIFREIKQAYKLGLDKLKNPWSILEIFVTCLSLSMVVLYFLRIKFTAEVVKDMRNDPTRFVSLHYTAFLDEWIKCLMGLIVFFSFIKIVRLLRFNRRMSLLAQTLKLCIPKIGAFVIVYGIAFFAYAQLACLVFGQNAEGFMTIPRSAATLMDTLLGKFTLKEMSDINRLIGPTFFYIYTLSMIFILINMFMSIINDSFAEVNSDVSKQANDYEIVDFM 498          

Query:  353 LRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAAS-----TTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLY-YENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTP-----------WVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEY-FFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKER 1816
            ++E++ Y  F+ V++++++G     A+     L  +F+    +D+S     S     +  + FW +    L+ GLY  +WYN     SD+  FL  + + ++G  R+RQ+RV+   C +   + G + QC   YS  +E      +    P           W Y +SS L +  Y G +A Y GGG+  +L   +  +   +  L  + W+DR TRA+ ++FTVY+   NL C   L+ E  P+GG    S+    ++ RY G+   FVL CE+LFV+F VY+  ++  EI      Y F   W+ +++++   S T  +   VR    ++ + T   + ++  NF +L      F  + A   F   +K  +   FNK M+ L+ TL   +K+LA F+I+F ++F+AF    YLIF  ++  F  +   + TL  ++LG F + +L   +R+  P  F FY   V F+L NMF++II + +  VK +   Q NE+EI D++ E+
Sbjct:  611 IQEILFYALFVWVVLVVAYGHRDPNAHVMNQGLEDVFSGRAKHDHSVPDGHSLLFQVSDITSFWNWTEAVLIPGLYSESWYNG---RSDKPGFLADHTSWMLGTARMRQLRVKAGDCKVHDVYSGYLAQCNGPYSWDTEDTTPVFRPGWRPAPSNYSTAQNAWKYRDSSELRSLPYLGKLALYSGGGYAFDLGKKE-KAMAMLAQLKRDKWVDRSTRAIFVEFTVYSPYTNLHCVGYLLLEVLPSGGTSPFSELLVTRIDRYAGNFMIFVLLCEILFVLFTVYFTYKQGKEIAREGVAYHFHEYWSWVELVLSGCSWTSIVLYFVRFGINKSTVLTYHKDTSVFVNFHALAASDQVFGYVYAFVAFFVSLKFLRLFRFNKRMSLLATTLKCSAKELAHFSIVFGLVFMAFVHFCYLIFSTELYIFHTVLSTVETLISVMLGKFSYERLLQTNRLLAPFMFFFYSIVVVFILINMFISIIIENFQRVKSQNDLQSNEYEIVDFMTEQ 1112          

Query:  329 RQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNS--------GTFAASTTESDFWKFLTGPLLNGLYWTTWYNN-----INFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTE--------------YQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKER 1816
            +++ +   L+E++ Y  F+AVL+++++G     AY     L   F + + +  S        GT      +S  W +    L+  LY    YN        +  D++N+L      +G+ RLR  RV+N SC+IP +      +C+  +S S+   D Y       W++ N S   +                Y G +  Y GGG+  +L      +   +  L ++ W++  TR V I+F +YNAN NLF    L  EF PTGG     +F+  +L  YVG    FVLA E++ ++F+ Y++  E   +  LK +YF   WN L++ +I+           R   V      L  N     +F+         + +I I +F   ++  K + FN+ M  L  T++  +K +  F I F ++FI+FA  G +IFG  ++ F      + T   I LGDFD+ ++E  +R+ G +YF  +++F+   L NMFLAII D++ EVK    + KNE+E+ +++ +R
Sbjct:  606 KEIQMSMILKEILAYFIFIAVLLLVAYGNRDPNAYLLRKTLVEEFVSLDESGVSLDEVQWKNGTIIVGDGDS-LWHWARETLIKNLYPGNLYNGKPDKYTGYLEDRVNYL------VGISRLRLERVKNGSCTIPKEMDRFFDECYGEFSYSNSDSDDY----EVEWMFLNKSAAPSARKRRSIAEQFSFGFPYWGKMNFYSGGGYPADLGYDYPTALTVVADLHSHNWVNSNTRGVFIEFAIYNANTNLFGVAFLYVEFLPTGGAFPHGEFKVARLYSYVGPFANFVLAMEVIMLLFMFYFVYREVKSMYKLKKKYFKGFWNWLEVAMIVLEFLMLGLFFARMWEVDKNFIELHHNPKDFVSFQYALASDETLNYVIGILVFFVTIRFIKLLRFNRRMALLGNTIALIAKPIGQFLISFTLVFISFAFFGNMIFGIGLDKFRSFTTTMMTQLNICLGDFDYLEMEEENRMLGRIYFFSFMYFIVMYLMNMFLAIINDSFSEVKTSNDDLKNEYEMVEFILDR 1117          

Query:  200 YGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFN-DNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSL--------------------------EEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
            Y   T +  ++    +P  C  R    IR LW T   ED   +R+ Y+   LREL+ YI FL  + I+++GM +   Y++T  +S LF  +  + +N  TF + +T  DFWK+  GP L G+YW  WYNN +   +Q +F+YYEN L+G+PRLRQVRV N++CSI  D + E++ C+  Y+ S+E    +G QN T WV+T  S ++ + + G V+ YGGGG+Y +L+ T+ +S   +  L ++LW+DRGTRA+ +DF+VYN N+NL C  +L+ EFP TGG+L S QF+TV+LI+YV S D+FV  CE+ F +F++YY+VEE LEI + +  YF ++WN LD+L++  S+   I +I R     ++++ L  N   H +F+SL   Q+QF+N+ A+ +F  WVK+FK+I+FNKTM+QLS T+SRC+KDL GFAIMFFIIF+A+AQL YL+FG QVNDFS  Q  ++T FRIILGDFDF +++ A+ + GP+YF+ +V F+FF+L NMFLAII DTY EVK ++A  ++E E+ D++K+     L KL LKK  + DI +++        GK+++DE   +LK +G+ +AEI+A+FA+YD DGD  L E +   M+ +LE ++  LDLE    ++ +   +     P                              EE++ L RRVDRM+++   IV+KID V+  LE +E+ K + R+ +  +L+
Sbjct:  113 YPTQTLNGQQQDRHEHPG-CMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGNQ-SFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKGL-ENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGPIYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSL----RQAGGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLE----RNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLD 828          

Query:  200 YGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFN-DNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSL--------------------------EEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
            Y   T +  ++    +P  C  R    IR LW T   ED   +R+ Y+   LREL+ YI FL  + I+++GM +   Y++T  +S LF  +  + +N  TF + +T  DFWK+  GP L G+YW  WYNN +   +Q +F+YYEN L+G+PRLRQVRV N++CSI  D + E++ C+  Y+ S+E    +G QN T WV+T  S ++ + + G V+ YGGGG+Y +L+ T+ +S   +  L ++LW+DRGTRA+ +DF+VYN N+NL C  +L+ EFP TGG+L S QF+TV+LI+YV S D+FV  CE+ F +F++YY+VEE LEI + +  YF ++WN LD+L++  S+   I +I R     ++++ L  N   H +F+SL   Q+QF+N+ A+ +F  WVK+FK+I+FNKTM+QLS T+SRC+KDL GFAIMFFIIF+A+AQL YL+FG QVNDFS  Q  ++T FRIILGDFDF +++ A+ + GP+YF+ +V F+FF+L NMFLAII DTY EVK ++A  ++E E+ D++K+     L KL LKK  + DI +++        GK+++DE   +LK +G+ +AEI+A+FA+YD DGD  L E +   M+ +LE ++  LDLE    ++ +   +     P                              EE++ L RRVDRM+++   IV+KID V+  LE +E+ K + R+ +  +L+
Sbjct:  113 YPTQTLNGQQQDRHEHPG-CMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGNQ-SFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKGL-ENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGPIYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSL----RQAGGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLE----RNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLD 828          

Query:  152 YGTRELPSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEI-----QYEKSEI------LNKTRDVI-LPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKA-------RSRETMGII 2293
            YG R  P    D  Y    + K        +   S    F   I+ LW T  TE+   +R+ YI+TTLREL++Y+ FL  + ++++GMT+   Y+FT  ++ LF  S   D    F +  T +DFW F  GPLL+GLYWT WYN  +  +   +F+YYEN L+G+PR+RQ++++N+SC +  DF+ EI  C+  Y    E   ++G  N T W Y     +  + + G+++TY G G+Y +L+ T+  S   + TL +N W+ RGTR V IDF+ YNANIN+FC I L+ EFP TGG + S Q RTVKL+RYV   D+F+L CE +F VFI+YY+VEE LE+++ +F Y  S+WNILDI+VI+ +L    FN+ RT+ V N++  L+ N NI+ +FE L FWQ Q++N+ A+ LF AW+K+FKYISFNKTMTQLS TL RC+KD+ GFA+MFFI+F A+AQLGYL+FG +V+ FS    CI+T FRIILGDF+F  ++ A+R+ GP+YFV YVFFVFFVL NMFLAII DTY EVKEEL +QK+E +I D +K+       +L LKKDKI D+Q A+ AG     G++ F ++K  L   G+ D EI A F+++D DG++ LD  EQ  M++EL++++++L  E+      YEK  +       ++ R V     V  +++++L R+V ++  +   I ++++ +L  +   EK K         +RE  G++
Sbjct:   46 YGPRPAPQGPVDSPYSLDAAGKFPEASVQRVKKKSGCCSF---IKGLWGTALTENVSNNREKYIRTTLRELLVYLLFLLDICLLTYGMTSSSTYYFTKAMTDLFVNSG-GDAGVAFQSIGTMADFWSFAQGPLLDGLYWTKWYNQQSLNNGNQSFIYYENMLLGVPRMRQIKMKNNSCKVHQDFKDEIFGCYDVYDEKKEDDLNFGLINGTAWTYHTEKEMRGSSHWGLLSTYSGAGYYQDLDRTRERSAEILSTLMDNCWLGRGTRVVFIDFSAYNANINMFCVISLMVEFPATGGAVPSYQIRTVKLLRYVTRWDYFILGCEAVFCVFILYYMVEEVLELRIHRFSYLKSVWNILDIVVILLALVAIAFNVFRTIKVDNLLGKLLENPNIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSTTLGRCAKDILGFAVMFFIVFFAYAQLGYLLFGTEVDTFSTFVKCIFTQFRIILGDFNFDAIDQANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELTSQKDELQITDIIKQSYMKTFTRLKLKKDKITDVQKALQAG----SGEIQFKDFKQTLIEMGHTDGEISAAFSKFDRDGNQVLDAEEQERMKRELQEKRDALSTELNHLGKNYEKEPVETESFPPHEQRSVSNQTFVDQQQFQSLARQVLQVQRSVADITSRMELILAQMGLQEKAKGGESGAGHEARERNGLL 770          

Query:  152 YGTRELPSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEI-----QYEKSEI------LNKTRDVI-LPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKA 2266
            YG R  P    D  Y    + K        +   S    F   I+ LW T  TE+   +R+ YI+TTLREL++Y+ FL  + ++++GMT+   Y+FT  ++ LF  S   D    F +  T +DFW F  GPLL+GLYWT WYN  +  +   +F+YYEN L+G+PR+RQ++++N+SC +  DF+ EI  C+  Y    E   ++G  N T W Y     +  + + G+++TY G G+Y +L+ T+  S   + TL +N W+ RGTR V IDF+ YNANIN+FC I L+ EFP TGG + S Q RTVKL+RYV   D+F+L CE +F VFI+YY+VEE LE+++ +F Y  S+WNILDI+VI+ +L    FN+ RT+ V N++  L+ N NI+ +FE L FWQ Q++N+ A+ LF AW+K+FKYISFNKTMTQLS TL RC+KD+ GFA+MFFI+F A+AQLGYL+FG +V+ FS    CI+T FRIILGDF+F  ++ A+R+ GP+YFV YVFFVFFVL NMFLAII DTY EVKEEL +QK+E +I D +K+       +L LKKDKI D+Q A+ AG     G++ F ++K  L   G+ D EI A F+++D DG++ LD  EQ  M++EL++++++L  E+      YEK  +       ++ R V     V  +++++L R+V ++  +   I ++++ +L  +   EK K 
Sbjct:   46 YGPRPAPQGPVDSPYSLDAAGKFPEASVQRVKKKSGCCSF---IKGLWGTALTENVSNNREKYIRTTLRELLVYLLFLLDICLLTYGMTSSSTYYFTKAMTDLFVNSG-GDAGVAFQSIGTMADFWSFAQGPLLDGLYWTKWYNQQSLNNGNQSFIYYENMLLGVPRMRQIKMKNNSCKVHQDFKDEIFGCYDVYDEKKEDDLNFGLINGTAWTYHTEKEMRGSSHWGLLSTYSGAGYYQDLDRTRERSAEILSTLMDNCWLGRGTRVVFIDFSAYNANINMFCVISLMVEFPATGGAVPSYQIRTVKLLRYVTRWDYFILGCEAVFCVFILYYMVEEVLELRIHRFSYLKSVWNILDIVVILLALVAIAFNVFRTIKVDNLLGKLLENPNIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSTTLGRCAKDILGFAVMFFIVFFAYAQLGYLLFGTEVDTFSTFVKCIFTQFRIILGDFNFDAIDQANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELTSQKDELQITDIIKQSYMKTFTRLKLKKDKITDVQKALQAG----SGEIQFKDFKQTLIEMGHTDGEISAAFSKFDRDGNQVLDAEEQERMKRELQEKRDALSTELNHLGKNYEKEPVETESFPPHEQRSVSNQTFVDQQQFQSLARQVLQVQRSVADITSRMELILAQMGLQEKAKG 754          

Query:  200 YGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFN-DNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYT---LFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSL--------------------------EEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILN 2299
            Y   T +  ++    +P  C  R    IR LW T   ED   +R+ Y+   LREL+ YI FL  + I+++GM +   Y++T  +S LF  +  + +N  TF + +T  DFWK+  GP L G+YW  WYNN +   +Q +F+YYEN L+G+PRLRQVRV N++CSI  D + E++ C+  Y+ S+E    +G QN T WV+T  S ++ + + G V+ YGGGG+Y +L+ T+ +S   +  L ++LW+DRGTRA+ +DF+VYN N+NL C  +L+ EFP TGG+L S QF+TV+LI+YV S D+FV  CE+ F +F++YY+VEE LEI + +  YF ++WN LD+L++  S+   I +I R     ++++ L  N   H +F+SL   Q+QF+N+ A+ +F  WVK+FK+I+FNKTM+QLS T+SRC+KDL GFAIMFFIIF+A+AQL YL+FG QVNDFS  Q  +     L+ +    F ++  E                       ++F          VK ++A  ++E E+ D++K+     L KL LKK  + DI +++        GK+++DE   +LK +G+ +AEI+A+FA+YD DGD  L E +   M+ +LE ++  LDL    E++ +   +     P                              EE++ L RRVDRM+++   IV+KID V+  LE +E+ K + R+ +  +L+
Sbjct:  113 YPTQTLNGQQQDRHEHPG-CMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGNQ-SFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKGL-ENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVSRTDLLYNLRPLHFLYSHGEKG-----------------ICTVSLF----------VKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSL----RQAGGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDL----ERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLD 804          

Query:  134 MHSNGDYGTRELPSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHKLNQNSVSTFQRH 2440
            MHSNGDYGTRELPSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDS+NTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLAGFAIMFFIIFIAFAQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPLYFVFYVFFVFFVLFNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLKKDKIIDIQNAV+AGDTNNDGKMDFDEW+VELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTR+IVTKIDTVLEALESIEKDKARSRETMGIILNTLNSND+NEDYDIDDDNDEIKKKKIKELIANEIHKLNQNSVSTFQRH
Sbjct:    1 MHSNGDYGTRELPSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSFNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLAGFAIMFFIIFIAFAQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPLYFVFYVFFVFFVLFNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLKKDKIIDIQNAVLAGDTNNDGKMDFDEWRVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRVIVTKIDTVLEALESIEKDKARSRETMGIILNTLNSNDNNEDYDIDDDNDEIKKKKIKELIANEIHKLNQNSVSTFQRH 769          

Query:  170 PSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEK--SEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNT 2302
            P AM  + ++ GK T    +E  F N N CWN+FK GIRSLWAT+HTE+   D+ LY  TT+RELV+Y+ FL +L II+F M     ++FTN L+ LF T+ FNDNSGTF++   +SDFWKFL GPLLNGLYW  WYN+ N  +++ N++Y+EN+L+G+PR+RQ+RV+N+SC IP+  Q ++ QC+AAYS + E K+S+G QNS+ W YT  S+L +  +QG + TYGGGGFYV+L ++Q +S N I++LFNN W+DR TRAV++DFT+YNANINLFC IKLVGEFPP GG+L S +FRTVKLIRYV  +DFFVLACE+LFV++++YYI+EE +EI   K  YF S+WN+LD++V+   + C  F+I R   +Q ++  L+ N NIHPNFE L+FWQLQ+DNL A  LFLA  K+FKYISFNK MTQL +TL+ C KDL GF++MFFI+F+AFAQ GYLIFG+Q+ ++ +   CI+TLFRIIL D +F +L   + I GPLYF+ YVFFVFF+LFNMFLAI+ D Y                 D++KE++  V  KLHLK++KI+D++NA+   DTNNDG MDFDEWK ELK RGY + EIE++FA++DTDGD+ LDE EQ+ M KEL DQK +L+ E+  E+   E L ++ D I P +S  +Y  L+R +D ++N   I+  K D +L+  ++I K K +SRE+  IILN 
Sbjct:   33 PCAMDGEYFDNGKITIIDYQEIGFKNEN-CWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY-----------------DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIES-DAIQP-ISYAKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNA 725          

Query:  170 PSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEK--SEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNT 2302
            P AM  + ++ GK T    +E  F N N CWN+FK GIRSLWAT+HTE+   D+ LY  TT+RELV+Y+ FL +L II+F M     ++FTN L+ LF T+ FNDNSGTF++   +SDFWKFL GPLLNGLYW  WYN+ N  +++ N++Y+EN+L+G+PR+RQ+RV+N+SC IP+  Q ++ QC+AAYS + E K+S+G QNS+ W YT  S+L +  +QG + TYGGGGFYV+L ++Q +S N I++LFNN W+DR TRAV++DFT+YNANINLFC IKLVGEFPP GG+L S +FRTVKLIRYV  +DFFVLACE+LFV++++YYI+EE +EI   K  YF S+WN+LD++V+   + C  F+I R   +Q ++  L+ N NIHPNFE L+FWQLQ+DNL A  LFLA  K+FKYISFNK MTQL +TL+ C KDL GF++MFFI+F+AFAQ GYLIFG+Q+ ++ +   CI+TLFRIIL D +F +L   + I GPLYF+ YVFFVFF+LFNMFLAI+ D Y                 D++KE++  V  KLHLK++KI+D++NA+   DTNNDG MDFDEWK ELK RGY + EIE++FA++DTDGD+ LDE EQ+ M KEL DQK +L+ E+  E+   E L ++ D I P +S  +Y  L+R +D ++N   I+  K D +L+  ++I K K +SRE+  IILN 
Sbjct:   22 PCAMDGEYFDNGKITIIDYQEIGFKNEN-CWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY-----------------DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIES-DAIQP-ISYAKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNA 714          

Query:  179 MSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEK--SEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNT 2302
            M  + ++ GK T    +E  F N N CWN+FK GIRSLWAT+HTE+   D+ LY  TT+RELV+Y+ FL +L II+F M     ++FTN L+ LF T+ FNDNSGTF++   +SDFWKFL GPLLNGLYW  WYN+ N  +++ N++Y+EN+L+G+PR+RQ+RV+N+SC IP+  Q ++ QC+AAYS + E K+S+G QNS+ W YT  S+L +  +QG + TYGGGGFYV+L ++Q +S N I++LFNN W+DR TRAV++DFT+YNANINLFC IKLVGEFPP GG+L S +FRTVKLIRYV  +DFFVLACE+LFV++++YYI+EE +EI   K  YF S+WN+LD++V+   + C  F+I R   +Q ++  L+ N NIHPNFE L+FWQLQ+DNL A  LFLA  K+FKYISFNK MTQL +TL+ C KDL GF++MFFI+F+AFAQ GYLIFG+Q+ ++ +   CI+TLFRIIL D +F +L   + I GPLYF+ YVFFVFF+LFNMFLAI+ D Y                 D++KE++  V  KLHLK++KI+D++NA+   DTNNDG MDFDEWK ELK RGY + EIE++FA++DTDGD+ LDE EQ+ M KEL DQK +L+ E+  E+   E L ++ D I P +S  +Y  L+R +D ++N   I+  K D +L+  ++I K K +SRE+  IILN 
Sbjct:    1 MDGEYFDNGKITIIDYQEIGFKNEN-CWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY-----------------DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIES-DAIQP-ISYAKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNA 690          

Query: 1181 MLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLXXXXXXXXXXXXXXXQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPXXXXXXXXXXXXXXXNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLXXXXXXXXQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHKLNQNSVSTFQRH 2440
            MLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLAGFAIMFFIIFIAFAQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPLYFVFYVFFVFFVLFNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLKKDKIIDIQNAV+AGDTNNDGKMDFDEW+VELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTR+IVTKIDTVLEALESIEKDKARSRETMGIILNTLNSND+NEDYDIDDDNDEIKKKKIKELIANEIHKLNQNSVSTFQRH
Sbjct:    1 MLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLAGFAIMFFIIFIAFAQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPLYFVFYVFFVFFVLFNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLKKDKIIDIQNAVLAGDTNNDGKMDFDEWRVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRVIVTKIDTVLEALESIEKDKARSRETMGIILNTLNSNDNNEDYDIDDDNDEIKKKKIKELIANEIHKLNQNSVSTFQRH 420