Malic enzyme

Overview
NameMalic enzyme
Smed IDSMED30007159
Length (bp)1766
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Malic enzyme (SMED30007159) t-SNE clustered cells

Violin plots show distribution of expression levels for Malic enzyme (SMED30007159) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Malic enzyme (SMED30007159) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Malic enzyme (SMED30007159) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30007159

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30007159h1SMcG0006537 dd_Smed_v4_21906_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30007159h1SMcG0006537 dd_Smed_v4_21906_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Malic enzyme vs. Ensembl Human
Match: ME1 (malic enzyme 1 [Source:HGNC Symbol;Acc:HGNC:6983])

HSP 1 Score: 543.888 bits (1400), Expect = 0.000e+0
Identity = 264/538 (49.07%), Postives = 371/538 (68.96%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY +  N  LNK L FT  ER+ L + G+LP    + + Q    +KN +  +S+ ++Y+ LMDL  +N KLF+ + +  I + +P++YTPTVG AC ++  +F KP GL+I+I D+ +I  +L  WPE  +KAI VTDGERILGLGDLG NGMGIP+GKLALYT  GG++P  CLP+ LD GT  + LL++  YIG +  R+ G +Y++F+D FME     YG + LIQFEDF N  AF  L KYR  YC FNDDIQGTASV VAGL+ A+RI   K+S+   LF GAGEA LGIA L+VM ++++GL  E A ++I+LVDSKGL+V+ R S  +T  K  FA + E +++L  IV+++ PT LIG +   G+F+ ++LK M   N +PII ALSNPTSK+EC+AE+ Y  TKG AIF+SGSPF+PV   N Q L PGQ NN+YVFPG+A  V+ C ++ I D +FL  A+ ++++VS K LE G+++P ++ I DVSL +A  + + A++ KTA + PEP +K+ F++ + Y+ +Y+
Sbjct:   15 GYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIVKGRAS--LTQEKEKFAHEHEEMKNLEAIVQEIKPTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKITKGRAIFASGSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTTAEVIAQQVSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTDYD 550
[Close]
BLAST of Malic enzyme vs. Ensembl Human
Match: ME3 (malic enzyme 3 [Source:HGNC Symbol;Acc:HGNC:6985])

HSP 1 Score: 524.628 bits (1350), Expect = 1.493e-180
Identity = 253/538 (47.03%), Postives = 361/538 (67.10%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY +  N  LNKG+ FT  ER  L + G++P   L+ D Q    ++  + + S+L+KYI LM L  +N KLF+ + +  + + +P++YTPTVG AC  +G  F +P GL+I+I DK ++  +L  WPE N+KA+ VTDGERILGLGDLG  GMGIP+GKLALYT  GGV+P  CLP+ LD GTN + LL++  YIG K +R+ G+ Y++ +D FM+     +G + LIQFEDF N  AF  L KYR  YCMFNDDIQGTASV VAG++ A+RI   K+S + F+F GAGEA +GIA LLVM ++++G+    A  +I++VDSKGL+V+ R    +   K +FA+    + SL E+V+ V PT +IG +   G+FT ++L+ M   + +PII ALSNPTSK+ECTAE+ Y  T+G  IF+SGSPF  V   + +  +PGQ NNAYVFPG+A  VI   I+ I D++FL  A+ ++++VS + L  G+++P +  I DVSL +A+ V +YA++   A+  PEP DK+ F++   Y  +Y+
Sbjct:   50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSH--LNHEKEMFAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLEDGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEPKDKEAFVRSLVYTPDYD 585
[Close]
BLAST of Malic enzyme vs. Ensembl Human
Match: ME3 (malic enzyme 3 [Source:HGNC Symbol;Acc:HGNC:6985])

HSP 1 Score: 524.628 bits (1350), Expect = 1.493e-180
Identity = 253/538 (47.03%), Postives = 361/538 (67.10%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY +  N  LNKG+ FT  ER  L + G++P   L+ D Q    ++  + + S+L+KYI LM L  +N KLF+ + +  + + +P++YTPTVG AC  +G  F +P GL+I+I DK ++  +L  WPE N+KA+ VTDGERILGLGDLG  GMGIP+GKLALYT  GGV+P  CLP+ LD GTN + LL++  YIG K +R+ G+ Y++ +D FM+     +G + LIQFEDF N  AF  L KYR  YCMFNDDIQGTASV VAG++ A+RI   K+S + F+F GAGEA +GIA LLVM ++++G+    A  +I++VDSKGL+V+ R    +   K +FA+    + SL E+V+ V PT +IG +   G+FT ++L+ M   + +PII ALSNPTSK+ECTAE+ Y  T+G  IF+SGSPF  V   + +  +PGQ NNAYVFPG+A  VI   I+ I D++FL  A+ ++++VS + L  G+++P +  I DVSL +A+ V +YA++   A+  PEP DK+ F++   Y  +Y+
Sbjct:   50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSH--LNHEKEMFAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLEDGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEPKDKEAFVRSLVYTPDYD 585
[Close]
BLAST of Malic enzyme vs. Ensembl Human
Match: ME3 (malic enzyme 3 [Source:HGNC Symbol;Acc:HGNC:6985])

HSP 1 Score: 521.546 bits (1342), Expect = 1.187e-179
Identity = 252/533 (47.28%), Postives = 358/533 (67.17%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFY 1653
            GY +  N  LNKG+ FT  ER  L + G++P   L+ D Q    ++  + + S+L+KYI LM L  +N KLF+ + +  + + +P++YTPTVG AC  +G  F +P GL+I+I DK ++  +L  WPE N+KA+ VTDGERILGLGDLG  GMGIP+GKLALYT  GGV+P  CLP+ LD GTN + LL++  YIG K +R+ G+ Y++ +D FM+     +G + LIQFEDF N  AF  L KYR  YCMFNDDIQGTASV VAG++ A+RI   K+S + F+F GAGEA +GIA LLVM ++++G+    A  +I++VDSKGL+V+ R    +   K +FA+    + SL E+V+ V PT +IG +   G+FT ++L+ M   + +PII ALSNPTSK+ECTAE+ Y  T+G  IF+SGSPF  V   + +  +PGQ NNAYVFPG+A  VI   I+ I D++FL  A+ ++++VS + L  G+++P +  I DVSL +A+ V +YA++   A+  PEP DK+ F++   Y
Sbjct:   50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSH--LNHEKEMFAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLEDGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEPKDKEAFVRSLVY 580
[Close]
BLAST of Malic enzyme vs. Ensembl Human
Match: ME2 (malic enzyme 2 [Source:HGNC Symbol;Acc:HGNC:6984])

HSP 1 Score: 508.449 bits (1308), Expect = 1.784e-174
Identity = 253/540 (46.85%), Postives = 366/540 (67.78%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKM-EPLESLLE-IVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++ N   NKG+ FT  ER+ L L G+LP  +   D Q   F +NLK+ +S LEKYIY+M +  +N KLF+ I    I  ++P++YTPTVG AC ++G IF +P GL+ISI D+ ++  I+  WPE +VKA+ VTDGERILGLGDLG  GMGIP+GKL LYT   G+ P  CLP+ +D GT+  +LL++ FY+G   +R   ++Y++ +D FM+     YG + LIQFEDFGNH AF FL+KYR  YC FNDDIQGTA+V +AGL+ A ++I K +SE+K LF GAGEA LGIA+L+VM M E+GLS++ A+++I++ D  GL+V+ R    +  ++  F     E +    E  V  + P+ +IG +G    FT +V++ M  IN +P+I ALSNPT+++ECTAEEAYT T+G  +F+SGSPF PVK  + +V  PGQ NN Y+FPG+A AVI C  + I D +FLEAAK L+ +++ ++L  G+++P +  I +VS+ +A+ V EY + +K A   PEP DK  +++++ + + Y+
Sbjct:   25 GKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGR-KAKIDSYQEPFTHSAPESIPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEAAKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKAKYVKERTWRSEYD 563
[Close]
BLAST of Malic enzyme vs. Ensembl Celegans
Match: men-1 (Malic enzyme [Source:UniProtKB/TrEMBL;Acc:Q9U296])

HSP 1 Score: 494.582 bits (1272), Expect = 6.181e-169
Identity = 248/540 (45.93%), Postives = 354/540 (65.56%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKD--NIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEM-GKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++ +  LNKG+ F+  ER+ L + G+LP   +  +QQ    +  L+++  NL KYI L  L  +N KL++ +   ++ E++P++YTPTVG AC  FG I+  P GLYI+I D     I +IL  WP  NV+AI +TDGERILGLGDLG  G+GIP+GKLALY  + G+ P +CLP+ LD GT+   LL + FY G + +R+ G +Y+  VD FM+   K +G D LIQFEDFGN  A+  L +Y+  YCMFNDDIQGTA+VVVAGL+ + RI  KK+S+ + +F GAG A  G+A + V  M ++GLS+E A  RIY+VD +GL+  +R S  +      FA+ +   ++LLE+VK V P  LIGAS   G+FT +++K M  +N +PII ALSNPTSK+ECTAE AY  T GA +F+SGSPF  V+   ++  PGQ NNAY+FPG+A   +  + K I DKLFL AA+ +++ VS K L    +++P +  I ++S+ +A+ V EY +R   A L P+P D ++F++Q  Y+  Y+
Sbjct:   51 GIDLLKSPGLNKGMAFSLHERQYLGVHGLLPPAFMTEEQQAYRIITKLRQQPDNLAKYIQLDSLQDRNEKLYYRVLCDNVKELMPIVYTPTVGQACQHFGFIYRNPKGLYITINDNSISKIHQILANWPTENVRAIVITDGERILGLGDLGTYGIGIPVGKLALYVALAGIRPEWCLPVILDVGTDNSELLNDPFYTGLRRKRVRGPEYDTLVDNFMKAATKRFGRDTLIQFEDFGNQNAYRLLDRYKGEYCMFNDDIQGTAAVVVAGLLASTRITKKKLSQERIVFLGAGGAATGVAEMCVRQMMDEGLSEEEACGRIYMVDIEGLITTSR-SKSLGERHVKFAKDLPDTKNLLEVVKTVKPGALIGASTVAGAFTEDIIKEMARLNPRPIIFALSNPTSKAECTAETAYRCTNGAVLFASGSPFENVEMNGKLYKPGQGNNAYIFPGVALGAVLFRTKNIPDKLFLLAARMVAEAVSEKSLNTYSRVYPRLKDIRELSVKIAVEVGEYCYRHDLATLHPKPDDMEMFIRQNLYSVEYD 589
[Close]
BLAST of Malic enzyme vs. Ensembl Celegans
Match: men-1 (Malic enzyme [Source:UniProtKB/TrEMBL;Acc:Q9U296])

HSP 1 Score: 494.582 bits (1272), Expect = 6.181e-169
Identity = 248/540 (45.93%), Postives = 354/540 (65.56%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKD--NIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEM-GKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++ +  LNKG+ F+  ER+ L + G+LP   +  +QQ    +  L+++  NL KYI L  L  +N KL++ +   ++ E++P++YTPTVG AC  FG I+  P GLYI+I D     I +IL  WP  NV+AI +TDGERILGLGDLG  G+GIP+GKLALY  + G+ P +CLP+ LD GT+   LL + FY G + +R+ G +Y+  VD FM+   K +G D LIQFEDFGN  A+  L +Y+  YCMFNDDIQGTA+VVVAGL+ + RI  KK+S+ + +F GAG A  G+A + V  M ++GLS+E A  RIY+VD +GL+  +R S  +      FA+ +   ++LLE+VK V P  LIGAS   G+FT +++K M  +N +PII ALSNPTSK+ECTAE AY  T GA +F+SGSPF  V+   ++  PGQ NNAY+FPG+A   +  + K I DKLFL AA+ +++ VS K L    +++P +  I ++S+ +A+ V EY +R   A L P+P D ++F++Q  Y+  Y+
Sbjct:   51 GIDLLKSPGLNKGMAFSLHERQYLGVHGLLPPAFMTEEQQAYRIITKLRQQPDNLAKYIQLDSLQDRNEKLYYRVLCDNVKELMPIVYTPTVGQACQHFGFIYRNPKGLYITINDNSISKIHQILANWPTENVRAIVITDGERILGLGDLGTYGIGIPVGKLALYVALAGIRPEWCLPVILDVGTDNSELLNDPFYTGLRRKRVRGPEYDTLVDNFMKAATKRFGRDTLIQFEDFGNQNAYRLLDRYKGEYCMFNDDIQGTAAVVVAGLLASTRITKKKLSQERIVFLGAGGAATGVAEMCVRQMMDEGLSEEEACGRIYMVDIEGLITTSR-SKSLGERHVKFAKDLPDTKNLLEVVKTVKPGALIGASTVAGAFTEDIIKEMARLNPRPIIFALSNPTSKAECTAETAYRCTNGAVLFASGSPFENVEMNGKLYKPGQGNNAYIFPGVALGAVLFRTKNIPDKLFLLAARMVAEAVSEKSLNTYSRVYPRLKDIRELSVKIAVEVGEYCYRHDLATLHPKPDDMEMFIRQNLYSVEYD 589
[Close]
BLAST of Malic enzyme vs. Ensembl Celegans
Match: men-1 (Malic enzyme [Source:UniProtKB/TrEMBL;Acc:Q9U296])

HSP 1 Score: 494.582 bits (1272), Expect = 6.181e-169
Identity = 248/540 (45.93%), Postives = 354/540 (65.56%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKD--NIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEM-GKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++ +  LNKG+ F+  ER+ L + G+LP   +  +QQ    +  L+++  NL KYI L  L  +N KL++ +   ++ E++P++YTPTVG AC  FG I+  P GLYI+I D     I +IL  WP  NV+AI +TDGERILGLGDLG  G+GIP+GKLALY  + G+ P +CLP+ LD GT+   LL + FY G + +R+ G +Y+  VD FM+   K +G D LIQFEDFGN  A+  L +Y+  YCMFNDDIQGTA+VVVAGL+ + RI  KK+S+ + +F GAG A  G+A + V  M ++GLS+E A  RIY+VD +GL+  +R S  +      FA+ +   ++LLE+VK V P  LIGAS   G+FT +++K M  +N +PII ALSNPTSK+ECTAE AY  T GA +F+SGSPF  V+   ++  PGQ NNAY+FPG+A   +  + K I DKLFL AA+ +++ VS K L    +++P +  I ++S+ +A+ V EY +R   A L P+P D ++F++Q  Y+  Y+
Sbjct:   51 GIDLLKSPGLNKGMAFSLHERQYLGVHGLLPPAFMTEEQQAYRIITKLRQQPDNLAKYIQLDSLQDRNEKLYYRVLCDNVKELMPIVYTPTVGQACQHFGFIYRNPKGLYITINDNSISKIHQILANWPTENVRAIVITDGERILGLGDLGTYGIGIPVGKLALYVALAGIRPEWCLPVILDVGTDNSELLNDPFYTGLRRKRVRGPEYDTLVDNFMKAATKRFGRDTLIQFEDFGNQNAYRLLDRYKGEYCMFNDDIQGTAAVVVAGLLASTRITKKKLSQERIVFLGAGGAATGVAEMCVRQMMDEGLSEEEACGRIYMVDIEGLITTSR-SKSLGERHVKFAKDLPDTKNLLEVVKTVKPGALIGASTVAGAFTEDIIKEMARLNPRPIIFALSNPTSKAECTAETAYRCTNGAVLFASGSPFENVEMNGKLYKPGQGNNAYIFPGVALGAVLFRTKNIPDKLFLLAARMVAEAVSEKSLNTYSRVYPRLKDIRELSVKIAVEVGEYCYRHDLATLHPKPDDMEMFIRQNLYSVEYD 589
[Close]
BLAST of Malic enzyme vs. Ensembl Fly
Match: Men (gene:FBgn0002719 transcript:FBtr0082661)

HSP 1 Score: 568.54 bits (1464), Expect = 0.000e+0
Identity = 268/537 (49.91%), Postives = 376/537 (70.02%), Query Frame = 1 
Query:   55 SGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANY 1665
            SG+  + +   +KGL FT  ER+ L + G+LP +V    +Q +     L     +L+KY+YL+ L  +N +LF+ + S  I+ ++PL+YTPTVG AC ++  I     G++ISIKDK +I  +L  WPE +V+AI VTDGERILGLGDLGANGMGIP+GKL+LYT + G+ PS CLPITLD GTNT+S+L++  YIG +  R  G+ Y+EF+D FM  C++ +G + LIQFEDF N  AF  L KYR ++C FNDDIQGTASV VAGL+ +++I   ++ +N  LF GAGEA LGIA+L +M M+ +GL++E A+ RI++VDS+G++  +RP GG+T  K  FA+  EP+++L E V+KV P VLIGA+ Q G+F  E+L+ M DIN  PII ALSNPTSK+ECTAEEAYT TKG  IF+SGSPF PV Y N+   PGQ NN+Y+FPG+A  V+   +  I +++FL AA+ L++ VS  DL  G ++P +  I   S+ +A  + EYA+++  A +RPEPV+K  F++ + Y+ +Y
Sbjct:  213 SGFTRLLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLSERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPETDVRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYIGLRERRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTASVAVAGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGVITRDRPKGGLTEHKLHFAQLHEPIDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPIIFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTYNNKKFYPGQGNNSYIFPGVALGVLCAGMLNIPEQVFLVAAERLAELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATVRPEPVNKLAFIKAQMYDLDY 749
[Close]
BLAST of Malic enzyme vs. Ensembl Fly
Match: Men (gene:FBgn0002719 transcript:FBtr0082660)

HSP 1 Score: 568.54 bits (1464), Expect = 0.000e+0
Identity = 268/537 (49.91%), Postives = 376/537 (70.02%), Query Frame = 1 
Query:   55 SGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANY 1665
            SG+  + +   +KGL FT  ER+ L + G+LP +V    +Q +     L     +L+KY+YL+ L  +N +LF+ + S  I+ ++PL+YTPTVG AC ++  I     G++ISIKDK +I  +L  WPE +V+AI VTDGERILGLGDLGANGMGIP+GKL+LYT + G+ PS CLPITLD GTNT+S+L++  YIG +  R  G+ Y+EF+D FM  C++ +G + LIQFEDF N  AF  L KYR ++C FNDDIQGTASV VAGL+ +++I   ++ +N  LF GAGEA LGIA+L +M M+ +GL++E A+ RI++VDS+G++  +RP GG+T  K  FA+  EP+++L E V+KV P VLIGA+ Q G+F  E+L+ M DIN  PII ALSNPTSK+ECTAEEAYT TKG  IF+SGSPF PV Y N+   PGQ NN+Y+FPG+A  V+   +  I +++FL AA+ L++ VS  DL  G ++P +  I   S+ +A  + EYA+++  A +RPEPV+K  F++ + Y+ +Y
Sbjct:  217 SGFTRLLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLSERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPETDVRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYIGLRERRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTASVAVAGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGVITRDRPKGGLTEHKLHFAQLHEPIDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPIIFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTYNNKKFYPGQGNNSYIFPGVALGVLCAGMLNIPEQVFLVAAERLAELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATVRPEPVNKLAFIKAQMYDLDY 753
[Close]
BLAST of Malic enzyme vs. Ensembl Fly
Match: Men (gene:FBgn0002719 transcript:FBtr0330025)

HSP 1 Score: 567 bits (1460), Expect = 0.000e+0
Identity = 271/547 (49.54%), Postives = 381/547 (69.65%), Query Frame = 1 
Query:   55 SGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE*LRSI*KTH 1695
            SG+  + +   +KGL FT  ER+ L + G+LP +V    +Q +     L     +L+KY+YL+ L  +N +LF+ + S  I+ ++PL+YTPTVG AC ++  I     G++ISIKDK +I  +L  WPE +V+AI VTDGERILGLGDLGANGMGIP+GKL+LYT + G+ PS CLPITLD GTNT+S+L++  YIG +  R  G+ Y+EF+D FM  C++ +G + LIQFEDF N  AF  L KYR ++C FNDDIQGTASV VAGL+ +++I   ++ +N  LF GAGEA LGIA+L +M M+ +GL++E A+ RI++VDS+G++  +RP GG+T  K  FA+  EP+++L E V+KV P VLIGA+ Q G+F  E+L+ M DIN  PII ALSNPTSK+ECTAEEAYT TKG  IF+SGSPF PV Y N+   PGQ NN+Y+FPG+A  V+   +  I +++FL AA+ L++ VS  DL  G ++P +  I   S+ +A  + EYA+++  A +RPEPV+K  F++ + Y+ +Y   RS+  T+
Sbjct:   32 SGFTRLLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLSERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPETDVRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYIGLRERRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTASVAVAGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGVITRDRPKGGLTEHKLHFAQLHEPIDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPIIFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTYNNKKFYPGQGNNSYIFPGVALGVLCAGMLNIPEQVFLVAAERLAELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATVRPEPVNKLAFIKAQMYDLDYP--RSVPATY 576
[Close]
BLAST of Malic enzyme vs. Ensembl Fly
Match: Men-b (gene:FBgn0029155 transcript:FBtr0301707)

HSP 1 Score: 550.821 bits (1418), Expect = 0.000e+0
Identity = 265/537 (49.35%), Postives = 358/537 (66.67%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G   I +  LNKGL FT  ER+ L + G+ P      ++Q +L    +   +  L KY+YL DL+ +N +LFF   S +I +++P++YTPTVG AC +FG I+ +P GL+I+  D+ +I  ++  WPE NV+AICVTDGERILGLGDLGA GMGIP+GKLALYT + G+ P  CLPI +D GTN   LL++  Y+G + +R++G +Y+EF+D FME  ++ YG + LIQFEDFGNH AF FL KYR TYC FNDDIQGTASV VAGL  + RI  K   +  FLF GAGEA +GIA L V  M +DG+  E A  RIY+VD  GL+ ++R  G +   K  +A+ + P+  L EIV  + P+VLIGAS   G FT E+L+TM D N +P++ ALSNPTSK+ECTAE+AY  T    IFSSGSPF PV+ G++   PGQ NNAY+FPG+   VI      I D++FL AA+ L+  V   D+E G ++P +  I +VS+ +A+ V + A+    A+  PEP DK+ +L+ + YN NYE
Sbjct:   53 GIDHIRDPRLNKGLAFTLEERQTLGIHGLQPARFKTQEEQLQLCKIAVNRYTEPLNKYLYLSDLYDRNERLFFRFLSENIEDLMPIVYTPTVGLACQRFGLIYRRPHGLFITYNDRGHIFDVMKNWPEPNVRAICVTDGERILGLGDLGACGMGIPVGKLALYTALAGIKPHQCLPIVVDVGTNNIDLLEDPLYVGLRQKRVVGREYDEFIDEFMEAVVQRYGQNTLIQFEDFGNHNAFRFLDKYRNTYCTFNDDIQGTASVAVAGLYASKRITGKSFKDYTFLFAGAGEAAIGIADLTVKAMVQDGVPIEEAYNRIYMVDIDGLLTKSRKVGNLDGHKIHYAKDINPMSDLAEIVSTIKPSVLIGASAAAGIFTPEILRTMADNNERPVVFALSNPTSKAECTAEDAYKHTDARVIFSSGSPFPPVQIGDKTFYPGQGNNAYIFPGVGLGVICTGTHHIPDEMFLIAAQELANFVEPSDIERGSLYPPLSSIRNVSMNIAVGVTKCAYDRGLASTYPEPQDKRKWLENQLYNFNYE 589
[Close]
BLAST of Malic enzyme vs. Ensembl Fly
Match: Men-b (gene:FBgn0029155 transcript:FBtr0301708)

HSP 1 Score: 550.051 bits (1416), Expect = 0.000e+0
Identity = 265/537 (49.35%), Postives = 358/537 (66.67%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G   I +  LNKGL FT  ER+ L + G+ P      ++Q +L    +   +  L KY+YL DL+ +N +LFF   S +I +++P++YTPTVG AC +FG I+ +P GL+I+  D+ +I  ++  WPE NV+AICVTDGERILGLGDLGA GMGIP+GKLALYT + G+ P  CLPI +D GTN   LL++  Y+G + +R++G +Y+EF+D FME  ++ YG + LIQFEDFGNH AF FL KYR TYC FNDDIQGTASV VAGL  + RI  K   +  FLF GAGEA +GIA L V  M +DG+  E A  RIY+VD  GL+ ++R  G +   K  +A+ + P+  L EIV  + P+VLIGAS   G FT E+L+TM D N +P++ ALSNPTSK+ECTAE+AY  T    IFSSGSPF PV+ G++   PGQ NNAY+FPG+   VI      I D++FL AA+ L+  V   D+E G ++P +  I +VS+ +A+ V + A+    A+  PEP DK+ +L+ + YN NYE
Sbjct:   53 GIDHIRDPRLNKGLAFTLEERQTLGIHGLQPARFKTQEEQLQLCKIAVNRYTEPLNKYLYLSDLYDRNERLFFRFLSENIEDLMPIVYTPTVGLACQRFGLIYRRPHGLFITYNDRGHIFDVMKNWPEPNVRAICVTDGERILGLGDLGACGMGIPVGKLALYTALAGIKPHQCLPIVVDVGTNNIDLLEDPLYVGLRQKRVVGREYDEFIDEFMEAVVQRYGQNTLIQFEDFGNHNAFRFLDKYRNTYCTFNDDIQGTASVAVAGLYASKRITGKSFKDYTFLFAGAGEAAIGIADLTVKAMVQDGVPIEEAYNRIYMVDIDGLLTKSRKVGNLDGHKIHYAKDINPMSDLAEIVSTIKPSVLIGASAAAGIFTPEILRTMADNNERPVVFALSNPTSKAECTAEDAYKHTDARVIFSSGSPFPPVQIGDKTFYPGQGNNAYIFPGVGLGVICTGTHHIPDEMFLIAAQELANFVEPSDIERGSLYPPLSSIRNVSMNIAVGVTKCAYDRGLASTYPEPQDKRKWLENQLYNFNYE 589
[Close]
BLAST of Malic enzyme vs. Ensembl Zebrafish
Match: me2 (malic enzyme 2, NAD(+)-dependent, mitochondrial [Source:NCBI gene;Acc:445233])

HSP 1 Score: 538.88 bits (1387), Expect = 0.000e+0
Identity = 258/538 (47.96%), Postives = 365/538 (67.84%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++ N   NKG+ FT  ER+ L + G+LP  +   D Q   F KNLK+ S  L+KYIYLM +  +N +LF+ +    I  ++P++YTPTVG AC ++G IF +P GL+ISIKD+ +I  IL  WP+ +VKA+ VTDGERILGLGDLG  GMGIP+GKL LYT   G+ P  CLP+ +D GT+ + LL++ FY+G    R   ++Y++ +D FME  +  YG D LIQFEDFGNH AF FL+KYR  YC FNDDIQGTASV +AGL+ A R + K ++E+K LF GAGEA LGIA+L+VM M E G+S   AR++I++ D  GL+V++R     +  ++        ++S L+ V  + PT +IG SG    FT +V+K M ++N +PII ALSNPT+K+ECTAE+AY+ T+G  +F+SGSPF PV   + ++L PGQ NNAY+FPG+A AVI   ++ I D +FLEAAK L+ +++ ++L  G+++P +  I +VSL +A+ V EY +    A   PEPVDK+ +++   +N NY+
Sbjct:   25 GKPLMLNPRTNKGMAFTLKERQMLGIHGLLPSKIETQDTQAMRFQKNLKKMSDPLQKYIYLMGIQERNERLFYRVLMEDIEALMPIVYTPTVGLACTQYGHIFRRPKGLFISIKDQGHIRSILDNWPDTSVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPESCLPVCIDVGTDNEKLLRDPFYMGLYQRRDRSQRYDDLIDEFMEAVVDKYGQDTLIQFEDFGNHNAFRFLKKYREKYCTFNDDIQGTASVALAGLLAAQRAVGKPLTEHKVLFLGAGEAALGIANLIVMAMMESGMSQADARKKIWMFDKYGLLVKDRAYETDSNQEAFVHPDPGDVKSFLDAVNVIKPTAIIGVSGAGRLFTHDVIKAMGNLNERPIIFALSNPTAKAECTAEDAYSLTQGRCLFASGSPFAPVSLEDGRILTPGQGNNAYIFPGVALAVILSGVRHISDTVFLEAAKTLADQLTDEELSQGRLYPPLSNIREVSLQMAIKVVEYVYSKGMAFRYPEPVDKESYVRSVVWNTNYD 562
[Close]
BLAST of Malic enzyme vs. Ensembl Zebrafish
Match: me2 (malic enzyme 2, NAD(+)-dependent, mitochondrial [Source:NCBI gene;Acc:445233])

HSP 1 Score: 538.88 bits (1387), Expect = 0.000e+0
Identity = 258/538 (47.96%), Postives = 365/538 (67.84%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++ N   NKG+ FT  ER+ L + G+LP  +   D Q   F KNLK+ S  L+KYIYLM +  +N +LF+ +    I  ++P++YTPTVG AC ++G IF +P GL+ISIKD+ +I  IL  WP+ +VKA+ VTDGERILGLGDLG  GMGIP+GKL LYT   G+ P  CLP+ +D GT+ + LL++ FY+G    R   ++Y++ +D FME  +  YG D LIQFEDFGNH AF FL+KYR  YC FNDDIQGTASV +AGL+ A R + K ++E+K LF GAGEA LGIA+L+VM M E G+S   AR++I++ D  GL+V++R     +  ++        ++S L+ V  + PT +IG SG    FT +V+K M ++N +PII ALSNPT+K+ECTAE+AY+ T+G  +F+SGSPF PV   + ++L PGQ NNAY+FPG+A AVI   ++ I D +FLEAAK L+ +++ ++L  G+++P +  I +VSL +A+ V EY +    A   PEPVDK+ +++   +N NY+
Sbjct:   25 GKPLMLNPRTNKGMAFTLKERQMLGIHGLLPSKIETQDTQAMRFQKNLKKMSDPLQKYIYLMGIQERNERLFYRVLMEDIEALMPIVYTPTVGLACTQYGHIFRRPKGLFISIKDQGHIRSILDNWPDTSVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPESCLPVCIDVGTDNEKLLRDPFYMGLYQRRDRSQRYDDLIDEFMEAVVDKYGQDTLIQFEDFGNHNAFRFLKKYREKYCTFNDDIQGTASVALAGLLAAQRAVGKPLTEHKVLFLGAGEAALGIANLIVMAMMESGMSQADARKKIWMFDKYGLLVKDRAYETDSNQEAFVHPDPGDVKSFLDAVNVIKPTAIIGVSGAGRLFTHDVIKAMGNLNERPIIFALSNPTAKAECTAEDAYSLTQGRCLFASGSPFAPVSLEDGRILTPGQGNNAYIFPGVALAVILSGVRHISDTVFLEAAKTLADQLTDEELSQGRLYPPLSNIREVSLQMAIKVVEYVYSKGMAFRYPEPVDKESYVRSVVWNTNYD 562
[Close]
BLAST of Malic enzyme vs. Ensembl Zebrafish
Match: me3 (malic enzyme 3, NADP(+)-dependent, mitochondrial [Source:ZFIN;Acc:ZDB-GENE-041111-294])

HSP 1 Score: 506.138 bits (1302), Expect = 1.342e-173
Identity = 257/538 (47.77%), Postives = 362/538 (67.29%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY I  N  LNKG+ FT  ER  L + G+LP   L+ D Q    +K+ + +S+ L+KYI LM L  +N KLF+ + +  I E +P++YTPTVG AC ++G  F +P GL+I+I DK +I  +L  WPE ++KAI VTDGERILGLGDLG  GMGIP+GKLALYT  GGV P  CLP+ LD GT+ ++LL +  YIG K +R+ G++Y++ +D FM+     YG + LIQFEDF N  AF  L KYR  YC FNDDIQGTASV VAG++ A++I   K+S++KF+F GAGEA LGIA LL+M M ++G+    A +RI++VDSKGL+V+ R    +   K  FA     +++L E+V+ + PT +IG +   G+FT +++K M   N +PII ALSNPTSK+ECTAE+ YT T+G  IF+SGSPF  V   + +   PGQ NNAYVFPG+A  VI C ++ I D +FL  A+ +S+ V+ + L  G+++P +  I +VS  +A+ + ++A++   A+  PEP DK+ F+    YN++Y+
Sbjct:   49 GYDITRNPHLNKGMAFTLEERLQLGIHGLLPPCFLSQDVQVLRVMKSYETRSNPLDKYILLMTLQDRNEKLFYRVLTSDIEEFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDKGHIATMLNSWPEEDIKAIVVTDGERILGLGDLGGYGMGIPVGKLALYTACGGVPPQQCLPVLLDVGTDNQTLLDDPLYIGLKHKRVRGKEYDDLIDEFMQAVTDKYGMNCLIQFEDFANSNAFRILNKYRNRYCTFNDDIQGTASVAVAGILAALKITKNKLSDHKFVFQGAGEAALGIAHLLIMAMAKEGIPHAEAAQRIWMVDSKGLIVKGRSH--LNHEKEEFAHDHPHIKTLEEVVETIKPTAIIGVAAIGGAFTEKIIKNMAANNERPIIFALSNPTSKAECTAEQCYTLTEGRGIFASGSPFKKVTLADGRSFYPGQGNNAYVFPGVALGVIACGVRHISDDIFLTTAEAISEMVTEEHLAEGRLYPPLKTIREVSFKIAVKIVDHAYKQGIASWYPEPKDKEAFILSHVYNSDYD 584
[Close]
BLAST of Malic enzyme vs. Ensembl Zebrafish
Match: me1 (malic enzyme 1, NADP(+)-dependent, cytosolic [Source:ZFIN;Acc:ZDB-GENE-061013-438])

HSP 1 Score: 499.59 bits (1285), Expect = 3.470e-171
Identity = 246/538 (45.72%), Postives = 358/538 (66.54%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY +  N  LNKG+ F+  ER  L + G+LP   L+ D Q    L++ +    +L++Y++LM L  +N KLF+ + +  I   +P++YTPTVG AC ++G  F +P GL+I+I D+ +I  +L  WPE +++A+ VTDGERILGLGDLG  GMGIP+GKLALYT  GG+ P  CLP+ LD GT+ + LL++  YIG + +R+ G+ Y+E +D FM+     YG   LIQFEDF N  AF  L KYR  Y  FNDDIQGTA+V VAGL+ A+RI   KM ++  +F GAGEA +GI  L+VM M+++GL  E   ++I++VDSKGL+V+ R    +T  K  FA +   ++ L ++VK++ PT +IG +   G+FT E++K M   N  PII ALSNPTSK+ECTAE+ YT T+G  IF+SGSPF+PV   + +   PGQ NN+YVFPG+   V  C+++ I + +FL  A+ +++ V+ KDL  G+++P +  I +VS+ +A+ + EYA++ K A L PEP DK  F++   Y+ +Y+
Sbjct:   32 GYDVTRNPHLNKGMAFSLEERLQLGIHGLLPPCFLSQDVQVLRVLRSYELLKEDLDRYVFLMGLQDRNEKLFYRVLTSDIERFMPIVYTPTVGLACQQYGLTFRRPRGLFITIHDRSHIPTLLQSWPEKDIRAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGMPPQQCLPVMLDVGTDKEELLKDPLYIGLRHKRVRGQAYDELLDEFMKAITDRYGMKCLIQFEDFANINAFRLLSKYRNKYLTFNDDIQGTAAVAVAGLLAALRITKSKMCDHTIVFQGAGEAAMGIGELIVMAMEKEGLPREQCIKKIWMVDSKGLIVKGRDH--LTHEKERFAHEHAQMKKLEDVVKELKPTAIIGVAAIAGAFTEEIIKAMASFNKNPIIFALSNPTSKAECTAEQCYTLTEGRGIFASGSPFDPVTLPDGRKFYPGQGNNSYVFPGVGLGVTACEMRHIPEDVFLVTAEAIAELVTDKDLAEGRLYPPLSSIREVSIKLAVKIVEYAYKHKMATLHPEPQDKDAFIRSLIYSTDYQ 567
[Close]
BLAST of Malic enzyme vs. Ensembl Zebrafish
Match: me1 (malic enzyme 1, NADP(+)-dependent, cytosolic [Source:ZFIN;Acc:ZDB-GENE-061013-438])

HSP 1 Score: 499.59 bits (1285), Expect = 7.034e-171
Identity = 246/538 (45.72%), Postives = 358/538 (66.54%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY +  N  LNKG+ F+  ER  L + G+LP   L+ D Q    L++ +    +L++Y++LM L  +N KLF+ + +  I   +P++YTPTVG AC ++G  F +P GL+I+I D+ +I  +L  WPE +++A+ VTDGERILGLGDLG  GMGIP+GKLALYT  GG+ P  CLP+ LD GT+ + LL++  YIG + +R+ G+ Y+E +D FM+     YG   LIQFEDF N  AF  L KYR  Y  FNDDIQGTA+V VAGL+ A+RI   KM ++  +F GAGEA +GI  L+VM M+++GL  E   ++I++VDSKGL+V+ R    +T  K  FA +   ++ L ++VK++ PT +IG +   G+FT E++K M   N  PII ALSNPTSK+ECTAE+ YT T+G  IF+SGSPF+PV   + +   PGQ NN+YVFPG+   V  C+++ I + +FL  A+ +++ V+ KDL  G+++P +  I +VS+ +A+ + EYA++ K A L PEP DK  F++   Y+ +Y+
Sbjct:   32 GYDVTRNPHLNKGMAFSLEERLQLGIHGLLPPCFLSQDVQVLRVLRSYELLKEDLDRYVFLMGLQDRNEKLFYRVLTSDIERFMPIVYTPTVGLACQQYGLTFRRPRGLFITIHDRSHIPTLLQSWPEKDIRAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGMPPQQCLPVMLDVGTDKEELLKDPLYIGLRHKRVRGQAYDELLDEFMKAITDRYGMKCLIQFEDFANINAFRLLSKYRNKYLTFNDDIQGTAAVAVAGLLAALRITKSKMCDHTIVFQGAGEAAMGIGELIVMAMEKEGLPREQCIKKIWMVDSKGLIVKGRDH--LTHEKERFAHEHAQMKKLEDVVKELKPTAIIGVAAIAGAFTEEIIKAMASFNKNPIIFALSNPTSKAECTAEQCYTLTEGRGIFASGSPFDPVTLPDGRKFYPGQGNNSYVFPGVGLGVTACEMRHIPEDVFLVTAEAIAELVTDKDLAEGRLYPPLSSIREVSIKLAVKIVEYAYKHKMATLHPEPQDKDAFIRSLIYSTDYQ 567
[Close]
BLAST of Malic enzyme vs. Ensembl Xenopus
Match: abhd4 (abhydrolase domain containing 4 [Source:Xenbase;Acc:XB-GENE-921768])

HSP 1 Score: 537.339 bits (1383), Expect = 0.000e+0
Identity = 255/538 (47.40%), Postives = 368/538 (68.40%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY I  +  LNKG+ F+  ER  L + G+LP   L+ D Q    L+N + +  +L++YI LM L  +N KLF+ + +  I   +P++YTPTVG AC ++G  F +P GL+I+I D+ +I  ++  WPE N+KA+ VTDGERILGLGDLG+ GMGIP+GKLALYT  GGV P  CLP+ LD GT+ + LL +  YIG +  R+ G++Y+E VD FM+   + YG + LIQFEDF N  AF  L  YR  YC FNDDIQGTA+V VAGL+ A+RI   K+S++  LF GAGEA +GIA L+VM M+++G   + A + I++VDSKGL+V+ R S  +   K  FA   + ++SL E+VK + PTVLIG +   G+FT +++K M   N++PII ALSNPTSK+ECTAE+ Y  T+G  IF+SGSPF+PV   + + L PGQ NNAYVFPG+A  V+ C ++ I D +FL  A+ ++++VS K LE G+++P +  I +VS+ +A+ + E A++  +A++ PEP +K+ F++ + Y+ +Y+
Sbjct:   33 GYDITRDPHLNKGMAFSLEERLQLGIHGLLPPCFLSQDVQVLRVLRNYERQKCDLDRYILLMGLQDRNEKLFYKVLTSDIERFMPVVYTPTVGLACQQYGLAFRRPRGLFITIHDRGHISTVMKSWPEDNIKAVVVTDGERILGLGDLGSYGMGIPVGKLALYTACGGVQPQECLPVMLDVGTDNQELLNDPLYIGLRHRRVRGKEYDELVDEFMKAVTERYGINCLIQFEDFANANAFRLLNMYRNKYCTFNDDIQGTAAVAVAGLLGALRITKNKLSDHTVLFQGAGEAAMGIADLIVMAMEKEGTPRDAAIKNIWMVDSKGLIVKGRAS--LNHEKERFAHPHKEMKSLEEVVKDIKPTVLIGVAAIGGAFTEQIIKDMASFNNRPIIFALSNPTSKAECTAEQCYRLTQGRGIFASGSPFDPVTLPDGRTLYPGQGNNAYVFPGVALGVVACGVRHISDDVFLTTAEIIAQQVSDKHLEEGRLYPPLQTIQEVSVKIAVKIVENAYKDNSASVFPEPENKEAFVRSQMYSTDYD 568
[Close]
BLAST of Malic enzyme vs. Ensembl Xenopus
Match: abhd4 (abhydrolase domain containing 4 [Source:Xenbase;Acc:XB-GENE-921768])

HSP 1 Score: 536.954 bits (1382), Expect = 0.000e+0
Identity = 255/538 (47.40%), Postives = 368/538 (68.40%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY I  +  LNKG+ F+  ER  L + G+LP   L+ D Q    L+N + +  +L++YI LM L  +N KLF+ + +  I   +P++YTPTVG AC ++G  F +P GL+I+I D+ +I  ++  WPE N+KA+ VTDGERILGLGDLG+ GMGIP+GKLALYT  GGV P  CLP+ LD GT+ + LL +  YIG +  R+ G++Y+E VD FM+   + YG + LIQFEDF N  AF  L  YR  YC FNDDIQGTA+V VAGL+ A+RI   K+S++  LF GAGEA +GIA L+VM M+++G   + A + I++VDSKGL+V+ R S  +   K  FA   + ++SL E+VK + PTVLIG +   G+FT +++K M   N++PII ALSNPTSK+ECTAE+ Y  T+G  IF+SGSPF+PV   + + L PGQ NNAYVFPG+A  V+ C ++ I D +FL  A+ ++++VS K LE G+++P +  I +VS+ +A+ + E A++  +A++ PEP +K+ F++ + Y+ +Y+
Sbjct:   16 GYDITRDPHLNKGMAFSLEERLQLGIHGLLPPCFLSQDVQVLRVLRNYERQKCDLDRYILLMGLQDRNEKLFYKVLTSDIERFMPVVYTPTVGLACQQYGLAFRRPRGLFITIHDRGHISTVMKSWPEDNIKAVVVTDGERILGLGDLGSYGMGIPVGKLALYTACGGVQPQECLPVMLDVGTDNQELLNDPLYIGLRHRRVRGKEYDELVDEFMKAVTERYGINCLIQFEDFANANAFRLLNMYRNKYCTFNDDIQGTAAVAVAGLLGALRITKNKLSDHTVLFQGAGEAAMGIADLIVMAMEKEGTPRDAAIKNIWMVDSKGLIVKGRAS--LNHEKERFAHPHKEMKSLEEVVKDIKPTVLIGVAAIGGAFTEQIIKDMASFNNRPIIFALSNPTSKAECTAEQCYRLTQGRGIFASGSPFDPVTLPDGRTLYPGQGNNAYVFPGVALGVVACGVRHISDDVFLTTAEIIAQQVSDKHLEEGRLYPPLQTIQEVSVKIAVKIVENAYKDNSASVFPEPENKEAFVRSQMYSTDYD 551
[Close]
BLAST of Malic enzyme vs. Ensembl Xenopus
Match: slc38a7 (solute carrier family 38 member 7 [Source:Xenbase;Acc:XB-GENE-5872357])

HSP 1 Score: 529.25 bits (1362), Expect = 0.000e+0
Identity = 259/540 (47.96%), Postives = 366/540 (67.78%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKM--EPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++ N   NKG+ FT  ER+ L L G+LP  V + D Q   F +NL +    L+KYIY+M +  +N KLF+ I    I  ++P++YTPTVG AC ++G IF +P GLYISI D+ +I  IL  WPE +VKA+ VTDGERILGLGDLG  GMGIP+GKL LYT   G+ P  CLP+ +D GT+  +LL++ FY+G   +R   + Y++ +D FM+     YG + LIQFEDFGNH AF FL+KYR  YC FNDDIQGTASV +AG++ A + I K ++E+K LF GAGEA LGIA+L+VM M E+G+S E ARERI++ D  GL+++ R   G+   +  FA     + + S L+ VK + PT +IG +G    FT +V+K M  IN +PII ALSNPT K+ECTAEEAYT T+G  +F+SGSPF+ V   + +   PGQ NNAY+FPG+A AVI   ++ I D++FLEAAK L++++++++L  G+++P +  I +VS+ +A+ V E+ +R+  A   PEPV K  +++ K ++ +Y+
Sbjct:   25 GKALLLNPRTNKGMAFTLQERQILGLQGLLPPKVESQDIQAARFHRNLSKMEDPLQKYIYIMGIQERNEKLFYRILLDDIEHLMPIVYTPTVGLACSQYGHIFRRPKGLYISILDRGHIRSILDHWPETDVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPQKCLPVVIDVGTDNPTLLKDPFYMGLYQKRDRTQLYDDLIDEFMDAVTDRYGQNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTASVALAGMLAAQKAIGKPITEHKILFLGAGEAALGIANLIVMSMMENGISAEAARERIWMFDKFGLLIQGR-GEGIDSNQESFAHSAPEQAVGSFLDAVKVLQPTAIIGVAGAGKLFTEDVIKEMASINERPIIFALSNPTVKAECTAEEAYTWTEGQCLFASGSPFDTVTLSDGRSFKPGQGNNAYIFPGVALAVILSGVRHISDRVFLEAAKALAEQLTAEELGQGRLYPPLSNIREVSICIAVKVMEFVYRNGMAFQYPEPVGKNAYIRSKVWSTDYD 563
[Close]
BLAST of Malic enzyme vs. Ensembl Xenopus
Match: slc38a7 (solute carrier family 38 member 7 [Source:Xenbase;Acc:XB-GENE-5872357])

HSP 1 Score: 529.25 bits (1362), Expect = 0.000e+0
Identity = 259/540 (47.96%), Postives = 366/540 (67.78%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKM--EPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++ N   NKG+ FT  ER+ L L G+LP  V + D Q   F +NL +    L+KYIY+M +  +N KLF+ I    I  ++P++YTPTVG AC ++G IF +P GLYISI D+ +I  IL  WPE +VKA+ VTDGERILGLGDLG  GMGIP+GKL LYT   G+ P  CLP+ +D GT+  +LL++ FY+G   +R   + Y++ +D FM+     YG + LIQFEDFGNH AF FL+KYR  YC FNDDIQGTASV +AG++ A + I K ++E+K LF GAGEA LGIA+L+VM M E+G+S E ARERI++ D  GL+++ R   G+   +  FA     + + S L+ VK + PT +IG +G    FT +V+K M  IN +PII ALSNPT K+ECTAEEAYT T+G  +F+SGSPF+ V   + +   PGQ NNAY+FPG+A AVI   ++ I D++FLEAAK L++++++++L  G+++P +  I +VS+ +A+ V E+ +R+  A   PEPV K  +++ K ++ +Y+
Sbjct:   34 GKALLLNPRTNKGMAFTLQERQILGLQGLLPPKVESQDIQAARFHRNLSKMEDPLQKYIYIMGIQERNEKLFYRILLDDIEHLMPIVYTPTVGLACSQYGHIFRRPKGLYISILDRGHIRSILDHWPETDVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPQKCLPVVIDVGTDNPTLLKDPFYMGLYQKRDRTQLYDDLIDEFMDAVTDRYGQNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTASVALAGMLAAQKAIGKPITEHKILFLGAGEAALGIANLIVMSMMENGISAEAARERIWMFDKFGLLIQGR-GEGIDSNQESFAHSAPEQAVGSFLDAVKVLQPTAIIGVAGAGKLFTEDVIKEMASINERPIIFALSNPTVKAECTAEEAYTWTEGQCLFASGSPFDTVTLSDGRSFKPGQGNNAYIFPGVALAVILSGVRHISDRVFLEAAKALAEQLTAEELGQGRLYPPLSNIREVSICIAVKVMEFVYRNGMAFQYPEPVGKNAYIRSKVWSTDYD 572
[Close]
BLAST of Malic enzyme vs. Ensembl Xenopus
Match: slc38a7 (solute carrier family 38 member 7 [Source:Xenbase;Acc:XB-GENE-5872357])

HSP 1 Score: 528.865 bits (1361), Expect = 0.000e+0
Identity = 259/540 (47.96%), Postives = 366/540 (67.78%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKM--EPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++ N   NKG+ FT  ER+ L L G+LP  V + D Q   F +NL +    L+KYIY+M +  +N KLF+ I    I  ++P++YTPTVG AC ++G IF +P GLYISI D+ +I  IL  WPE +VKA+ VTDGERILGLGDLG  GMGIP+GKL LYT   G+ P  CLP+ +D GT+  +LL++ FY+G   +R   + Y++ +D FM+     YG + LIQFEDFGNH AF FL+KYR  YC FNDDIQGTASV +AG++ A + I K ++E+K LF GAGEA LGIA+L+VM M E+G+S E ARERI++ D  GL+++ R   G+   +  FA     + + S L+ VK + PT +IG +G    FT +V+K M  IN +PII ALSNPT K+ECTAEEAYT T+G  +F+SGSPF+ V   + +   PGQ NNAY+FPG+A AVI   ++ I D++FLEAAK L++++++++L  G+++P +  I +VS+ +A+ V E+ +R+  A   PEPV K  +++ K ++ +Y+
Sbjct:   25 GKALLLNPRTNKGMAFTLQERQILGLQGLLPPKVESQDIQAARFHRNLSKMEDPLQKYIYIMGIQERNEKLFYRILLDDIEHLMPIVYTPTVGLACSQYGHIFRRPKGLYISILDRGHIRSILDHWPETDVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPQKCLPVVIDVGTDNPTLLKDPFYMGLYQKRDRTQLYDDLIDEFMDAVTDRYGQNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTASVALAGMLAAQKAIGKPITEHKILFLGAGEAALGIANLIVMSMMENGISAEAARERIWMFDKFGLLIQGR-GEGIDSNQESFAHSAPEQAVGSFLDAVKVLQPTAIIGVAGAGKLFTEDVIKEMASINERPIIFALSNPTVKAECTAEEAYTWTEGQCLFASGSPFDTVTLSDGRSFKPGQGNNAYIFPGVALAVILSGVRHISDRVFLEAAKALAEQLTAEELGQGRLYPPLSNIREVSICIAVKVMEFVYRNGMAFQYPEPVGKNAYIRSKVWSTDYD 563
[Close]
BLAST of Malic enzyme vs. Ensembl Mouse
Match: Me1 (malic enzyme 1, NADP(+)-dependent, cytosolic [Source:MGI Symbol;Acc:MGI:97043])

HSP 1 Score: 558.525 bits (1438), Expect = 0.000e+0
Identity = 271/538 (50.37%), Postives = 373/538 (69.33%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY +  +  LNK L FT  ER+ L + G+LP  +++ + Q    +KN +  +S+ ++Y+ LMDL  +N KLF+ +    + + +P++YTPTVG AC ++   F KP GL+ISI DK +I  +L  WPE  VKAI VTDGERILGLGDLG NGMGIP+GKLALYT  GGV+P  CLPITLD GT  + LL++  YIG +  R+ G +Y+ F+D FME     YG + LIQFEDF N  AF  L KYR  YC FNDDIQGTASV VAGL+ A+RI   K+S+   LF GAGEA LGIA L+VM M+++GLS E AR++I+LVDSKGL+V+ R S  +T  K +FA + E +++L  IV+K+ PT LIG +   G+FT ++LK M   N +PII ALSNPTSK+EC+AE+ Y  TKG AIF+SGSPF+PV   + + L PGQ NN+YVFPG+A  V+ C ++ I DK+FL  A+ +S++VS K L+ G+++P ++ I  VSL +A+ + + A++ K A + PEP +K+ F+  + Y+ NY+
Sbjct:   15 GYLLTRDPHLNKDLAFTLEERQQLNIHGLLPPCIISQELQVLRIIKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANRNAFRLLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLVVMAMEKEGLSKENARKKIWLVDSKGLIVKGRAS--LTEEKEVFAHEHEEMKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHIDDKVFLTTAEVISQQVSDKHLQEGRLYPPLNTIRGVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYD 550
[Close]
BLAST of Malic enzyme vs. Ensembl Mouse
Match: Me1 (malic enzyme 1, NADP(+)-dependent, cytosolic [Source:MGI Symbol;Acc:MGI:97043])

HSP 1 Score: 549.666 bits (1415), Expect = 0.000e+0
Identity = 266/525 (50.67%), Postives = 366/525 (69.71%), Query Frame = 1 
Query:   97 LGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            L FT  ER+ L + G+LP  +++ + Q    +KN +  +S+ ++Y+ LMDL  +N KLF+ +    + + +P++YTPTVG AC ++   F KP GL+ISI DK +I  +L  WPE  VKAI VTDGERILGLGDLG NGMGIP+GKLALYT  GGV+P  CLPITLD GT  + LL++  YIG +  R+ G +Y+ F+D FME     YG + LIQFEDF N  AF  L KYR  YC FNDDIQGTASV VAGL+ A+RI   K+S+   LF GAGEA LGIA L+VM M+++GLS E AR++I+LVDSKGL+V+ R S  +T  K +FA + E +++L  IV+K+ PT LIG +   G+FT ++LK M   N +PII ALSNPTSK+EC+AE+ Y  TKG AIF+SGSPF+PV   + + L PGQ NN+YVFPG+A  V+ C ++ I DK+FL  A+ +S++VS K L+ G+++P ++ I  VSL +A+ + + A++ K A + PEP +K+ F+  + Y+ NY+
Sbjct:    8 LAFTLEERQQLNIHGLLPPCIISQELQVLRIIKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANRNAFRLLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLVVMAMEKEGLSKENARKKIWLVDSKGLIVKGRAS--LTEEKEVFAHEHEEMKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHIDDKVFLTTAEVISQQVSDKHLQEGRLYPPLNTIRGVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYD 530
[Close]
BLAST of Malic enzyme vs. Ensembl Mouse
Match: Me2 (malic enzyme 2, NAD(+)-dependent, mitochondrial [Source:MGI Symbol;Acc:MGI:2147351])

HSP 1 Score: 528.865 bits (1361), Expect = 0.000e+0
Identity = 257/539 (47.68%), Postives = 368/539 (68.27%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKM-EPLESLLE-IVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANY 1665
            G  ++ N   NKG+ FT  ER+ L L G+LP  +   D Q   F +NLK+ +S LEKYIY+M +  +N KLF+ I    I  ++P++YTPTVG AC ++G IF +P GL+ISI D+ ++  I+  WPE +VKA+ VTDGERILGLGDLG  GMGIP+GKL LYT   G+ P  CLP+ +D GT+  +LL++ FY+G   +R   + Y++ +D FM+     YG + LIQFEDFGNH AF FL+KY+  YC FNDDIQGTA+V ++GL+ A R+I+K +SE+K LF GAGEA LGIA+L+V+ M E GLS+E A+ +I++ D  GL+V+ R +  +   +  +A    E + +  E  V K+ P+V+IG +G    FT  V+K M  IN +PII ALSNPT+++ECTAE+AYT T+G  +F+SGSPF PVK  + +V  PGQ NNAY+FPG+A AVI C+ + I D +FLEAAK L+ +++  +L  G+++PS+  I +VS  +A+ + EY + +K A   PEP DK  +++++ + +NY
Sbjct:   25 GKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCIDVGTDNMALLKDPFYMGLYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYQQKYCTFNDDIQGTAAVALSGLLAAQRVINKPVSEHKILFLGAGEAALGIANLIVLSMVESGLSEEEAQRKIWMFDKSGLLVKGR-TASIDSNQEPYAHAAPESIPATFEDAVNKLKPSVIIGVAGAGPLFTHGVIKAMASINERPIIFALSNPTAQAECTAEDAYTLTEGRCLFASGSPFEPVKLQDGRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKALTTQLTDAELAQGRLYPSLANIQEVSANIAIKLAEYLYANKMAFRYPEPEDKARYVRERIWRSNY 562
[Close]
BLAST of Malic enzyme vs. Ensembl Mouse
Match: Me3 (malic enzyme 3, NADP(+)-dependent, mitochondrial [Source:MGI Symbol;Acc:MGI:1916679])

HSP 1 Score: 525.398 bits (1352), Expect = 0.000e+0
Identity = 253/538 (47.03%), Postives = 362/538 (67.29%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY +  N  LNKG+ FT  ER  L + G++P   L+ D Q    ++  + + S+L+KYI LM L  +N KLF+ + +  + + +P++YTPTVG AC  +G  F +P GL+I+I DK +I  +L  WPE N+KA+ VTDGERILGLGDLG  GMGIP+GKLALYT  GGV+P  CLP+ LD GTN + LL++  YIG K +R+ GE+Y++ +D FM+     +G + LIQFEDF N  AF  L KYR  YCMFNDDIQGTASV VAG++ A+RI   ++S + F+F GAGEA +GIA LLVM ++++G+    A ++I++VDSKGL+V+ R    +   K +FA+    + SL E+V+ V PT +IG +   G+FT ++L+ M   + +PI+ ALSNPTSK+ECTAE+ Y  T+G  IF+SGSPF  V   + +   PGQ NNAYVFPG+A  VI   I+ I D++FL  A+ ++++VS + L  G+++P +  I DVSL +A+ V +YA++   A+  PEP DK+ F++   Y  +Y+
Sbjct:   50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYENQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHIATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVRGEEYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNRLSNHVFVFQGAGEAAMGIAHLLVMALEKEGIPKTEAIKKIWMVDSKGLIVKGRSH--LNHEKEMFAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIVFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLEDGRTFTPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAVKVLDYAYKHNLASYYPEPKDKEAFVKSLIYTPDYD 585
[Close]
BLAST of Malic enzyme vs. Ensembl Mouse
Match: Me3 (malic enzyme 3, NADP(+)-dependent, mitochondrial [Source:MGI Symbol;Acc:MGI:1916679])

HSP 1 Score: 61.6178 bits (148), Expect = 1.106e-11
Identity = 24/58 (41.38%), Postives = 39/58 (67.24%), Query Frame = 1 
Query:  202 KEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKP 375
            + + S+L+KYI LM L  +N KLF+ + +  + + +P++YTPTVG AC  +G  F +P
Sbjct:    3 ENQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRP 60
[Close]
BLAST of Malic enzyme vs. UniProt/SwissProt
Match: sp|P13697|MAOX_RAT (NADP-dependent malic enzyme OS=Rattus norvegicus OX=10116 GN=Me1 PE=1 SV=2)

HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0
Identity = 274/538 (50.93%), Postives = 375/538 (69.70%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY +  +  LNK L FT  ER+ L + G+LP  ++N + Q    +KN +  +S+ ++Y+ LMDL  +N KLF+ +   ++ + +P++YTPTVG AC ++   F KP GL+ISI DK +I  +L  WPE  VKAI VTDGERILGLGDLG NGMGIP+GKLALYT  GGV+P  CLPITLD GT  + LL++  YIG +  R+ G +Y+ F+D FME     YG + LIQFEDF N  AF  L KYR  YC FNDDIQGTASV VAGL+ A+RI   K+S+   LF GAGEA LGIA L+VM M+++GLS E AR++I+LVDSKGL+V+ R S  +T  K +FA + E +++L  IV+K+ PT LIG +   G+FT ++LK M   N +PII ALSNPTSK+EC+AEE Y  TKG AIF+SGSPF+PV   + + L PGQ NN+YVFPG+A  V+ C ++ I+D +FL  A+ +S++VS K LE G+++P ++ I DVSL +A+ + + A++ K A + PEP +K+ F+  + Y+ NY+
Sbjct:   15 GYLLTRDPHLNKDLAFTLEERQQLKIHGLLPPCIVNQEIQVLRVIKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSNVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANLNAFRLLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLIVMAMEKEGLSKEKARQKIWLVDSKGLIVKGRAS--LTEEKEVFAHEHEEMKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEECYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHINDSVFLTTAEVISQQVSDKHLEEGRLYPPLNTIRDVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYD 550
[Close]
BLAST of Malic enzyme vs. UniProt/SwissProt
Match: sp|P06801|MAOX_MOUSE (NADP-dependent malic enzyme OS=Mus musculus OX=10090 GN=Me1 PE=1 SV=2)

HSP 1 Score: 558.525 bits (1438), Expect = 0.000e+0
Identity = 271/538 (50.37%), Postives = 373/538 (69.33%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY +  +  LNK L FT  ER+ L + G+LP  +++ + Q    +KN +  +S+ ++Y+ LMDL  +N KLF+ +    + + +P++YTPTVG AC ++   F KP GL+ISI DK +I  +L  WPE  VKAI VTDGERILGLGDLG NGMGIP+GKLALYT  GGV+P  CLPITLD GT  + LL++  YIG +  R+ G +Y+ F+D FME     YG + LIQFEDF N  AF  L KYR  YC FNDDIQGTASV VAGL+ A+RI   K+S+   LF GAGEA LGIA L+VM M+++GLS E AR++I+LVDSKGL+V+ R S  +T  K +FA + E +++L  IV+K+ PT LIG +   G+FT ++LK M   N +PII ALSNPTSK+EC+AE+ Y  TKG AIF+SGSPF+PV   + + L PGQ NN+YVFPG+A  V+ C ++ I DK+FL  A+ +S++VS K L+ G+++P ++ I  VSL +A+ + + A++ K A + PEP +K+ F+  + Y+ NY+
Sbjct:   15 GYLLTRDPHLNKDLAFTLEERQQLNIHGLLPPCIISQELQVLRIIKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANRNAFRLLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLVVMAMEKEGLSKENARKKIWLVDSKGLIVKGRAS--LTEEKEVFAHEHEEMKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHIDDKVFLTTAEVISQQVSDKHLQEGRLYPPLNTIRGVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYD 550
[Close]
BLAST of Malic enzyme vs. UniProt/SwissProt
Match: sp|P37223|MAOX_MESCR (NADP-dependent malic enzyme OS=Mesembryanthemum crystallinum OX=3544 GN=MOD1 PE=2 SV=1)

HSP 1 Score: 552.747 bits (1423), Expect = 0.000e+0
Identity = 269/545 (49.36%), Postives = 371/545 (68.07%), Query Frame = 1 
Query:   46 NIGSGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSD-EGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE*LR 1677
            ++  G+ ++ +   NKGL FTE ER A  L G+LP +VL+ + QEK FL  L++    L+KY+ +MDL  +N KLF+ +   H+ E+LPL+YTPTVG  C K+G IF +P GL+IS+KDK  I ++L  WPE  ++ I VTDGERILGLGDLG  GMGIP+GKL+LY+ +GGV PS CLPITLD GTN + LL +EFYIG K +R  GE+Y EFV  FM    + YG  +L+QFEDF NH AF  L+KYR T+ +FNDDIQGTASVV+AGLI +++++   ++++KFLF GAGEA  GIA L+ + M +   +  E  R++I+LVDSKGLVV +R    +  FK  +A + EP+ +L++ V+ + PTVLIG SG+   FT EV++ M +IN+KP+I+ALSNPTS+SECTAEEAYT ++G AIF+SGSPF+PV+Y  +  +PGQANNAY+FPG    +I C    +HD + L A++ L+ +V+ +    G I+P    I  +S  +A  V   A+    A+  P+P D   F +   YN  Y   R
Sbjct:   42 SVACGHSLLRDPQHNKGLAFTEKERDAHFLRGLLPPVVLSQELQEKKFLTTLRQYQVPLQKYMAMMDLQERNEKLFYKLLVDHVEELLPLVYTPTVGEGCQKYGSIFRRPQGLFISLKDKGRILELLRNWPEKKIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYSALGGVCPSACLPITLDVGTNNQKLLDDEFYIGLKQKRATGEEYAEFVQEFMSAVKQNYGEKILVQFEDFANHNAFELLEKYRTTHLVFNDDIQGTASVVLAGLIASLKLLGGTLADHKFLFLGAGEAGTGIAELIALEMSKKTKAPVEQMRKKIWLVDSKGLVVSSRKE-TLQQFKLPWAHEHEPITTLIDAVQAIKPTVLIGTSGKGKQFTKEVVEAMANINAKPLILALSNPTSQSECTAEEAYTWSQGHAIFASGSPFDPVEYEGRTFVPGQANNAYIFPGFGLGLIMCGAIRVHDDMLLAASEALASQVTGEHFIKGLIYPPFKDIRKISAHIAAGVAAKAYELGLASRLPQPADLVKFAESCMYNPTYRSFR 585
[Close]
BLAST of Malic enzyme vs. UniProt/SwissProt
Match: sp|P28227|MAOX_ANAPL (NADP-dependent malic enzyme OS=Anas platyrhynchos OX=8839 GN=ME1 PE=1 SV=1)

HSP 1 Score: 549.666 bits (1415), Expect = 0.000e+0
Identity = 265/537 (49.35%), Postives = 375/537 (69.83%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANY 1665
            GY+++ +  LNKG+ FT  ER+ L + G+LP   L  D Q    LKN +  +S+L++YI LM L  +N KLF+ + +  I   +P++YTPTVG AC ++G  F +P GL+I+I D+ +I  +L  WPE+ +KAI VTDGERILGLGDLG  GMGIP+GKLALYT  GGV P  CLP+ LD GT+ ++LL++  YIG + +RI G+ Y++ +D FME     YG + LIQFEDF N  AF  L KYR  YC FNDDIQGTASV VAGL+ A+RI   ++S++  LF GAGEA LGIA+L+VM M+++G+S E A +RI++VDSKGL+V+ R S  +T  K+ FA +   +++L +IVK + P+VLIG +   G+FT E+L+ M   N +PII ALSNPTSK+ECTAE+ Y  T+G  IF+SGSPF+PV   N + L PGQ NN+YVFPG+A  VI C +K I + +FL  A+ ++++VS ++L+ G+++P +  I  VSL +A+ + E A+R+ TA+  P+P D + F+Q + Y+ +Y
Sbjct:    4 GYEVLRDPHLNKGMAFTLEERQQLNIHGLLPPCFLGQDVQVFSILKNFERLTSDLDRYILLMSLQDRNEKLFYKVLTSDIERFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDRGHIATMLKSWPESVIKAIVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVKPHECLPVMLDVGTDNEALLKDPLYIGLRHKRIRGQAYDDLLDEFMEAVTSRYGMNCLIQFEDFANANAFRLLHKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNRLSDHTVLFQGAGEAALGIANLIVMAMEKEGVSKEAAVKRIWMVDSKGLIVKGRAS--LTAEKTRFAHEHAEMKNLEDIVKDIKPSVLIGVAAIGGAFTKEILQDMAAFNKRPIIFALSNPTSKAECTAEQCYKYTEGRGIFASGSPFDPVTLPNGKTLYPGQGNNSYVFPGVALGVIACGLKHIGEDVFLTTAEVIAEQVSEENLQEGRLYPPLVTIQHVSLKIAVRIAEEAYRNNTASTYPQPKDLEAFIQSQIYSTDY 538
[Close]
BLAST of Malic enzyme vs. UniProt/SwissProt
Match: sp|P40927|MAOX_COLLI (NADP-dependent malic enzyme OS=Columba livia OX=8932 GN=ME1 PE=1 SV=1)

HSP 1 Score: 546.199 bits (1406), Expect = 0.000e+0
Identity = 265/537 (49.35%), Postives = 372/537 (69.27%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKY-GNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANY 1665
            GY+++ +  LNKG+ FT  ER+ L + G+LP   L  D Q    LKN +  +S+L++YI LM L  +N KLF+ + +  I   +P++YTPTVG AC  +G  F +P GL+I+I D+ +I  +L  WPE+ +KAI VTDGERILGLGDLG  GMGIP+GKLALYT  GGV P  CLP+ LD GT+ ++LL++  YIG + +RI G+ Y++ +D FME     YG + LIQFEDF N  AF  L KYR  YC FNDDIQGTASV VAGL+ A+RI   ++S++  LF GAGEA LGIA+L+VM MQ++G+S E A +RI++VDSKGL+V+ R S  +T  K  FA +   +++L +IVK + PTVLIG +   G+FT ++L+ M   N +PII ALSNPTSK+ECTAE+ Y  T+G  IF+SGSPF+PV     Q L PGQ NN+YVFPG+A  VI C +K I D +FL  A+ ++++VS ++L+ G+++P +  I  VSL +A+ + + A+R+ TA+  P+P D + F++ + Y+ +Y
Sbjct:    4 GYEVLRDPHLNKGMAFTLEERQQLNIHGLLPPCFLGQDAQVYSILKNFERLTSDLDRYILLMSLQDRNEKLFYKVLTSDIERFMPIVYTPTVGLACQHYGLAFRRPRGLFITIHDRGHIATMLQSWPESVIKAIVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVKPHQCLPVMLDVGTDNETLLKDPLYIGLRHKRIRGQAYDDLLDEFMEAVTSRYGMNCLIQFEDFANANAFRLLHKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNRLSDHTVLFQGAGEAALGIANLIVMAMQKEGVSKEEAIKRIWMVDSKGLIVKGRAS--LTPEKEHFAHEHCEMKNLEDIVKDIKPTVLIGVAAIGGAFTQQILQDMAAFNKRPIIFALSNPTSKAECTAEQLYKYTEGRGIFASGSPFDPVTLPSGQTLYPGQGNNSYVFPGVALGVISCGLKHIGDDVFLTTAEVIAQEVSEENLQEGRLYPPLVTIQQVSLKIAVRIAKEAYRNNTASTYPQPEDLEAFIRSQVYSTDY 538
[Close]
BLAST of Malic enzyme vs. TrEMBL
Match: A0A423T5V2 (Malic enzyme OS=Penaeus vannamei OX=6689 GN=C7M84_009761 PE=3 SV=1)

HSP 1 Score: 598.586 bits (1542), Expect = 0.000e+0
Identity = 280/549 (51.00%), Postives = 387/549 (70.49%), Query Frame = 1 
Query:   46 NIGSGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE*LRSI*KT 1692
            N+  G   + +  LNKG+ F+  ER+ L L G++P      ++Q  L  KN++     L K+IYL  L  +N +LF+ + S ++ E +P++YTPTVG AC KFG IF +P GL+ISI DK ++  +L  WPE +V+AI VTDGERILGLGDLG  GMGIP+GKL+LYT + G+ P  CLPI LD GTN K LL++EFYIG + ER+ GE Y+EF+D FM   ++ YG + LIQFEDFGNH AF FL+KYR  YC FNDDIQGTASV VAGL+ ++RI D K+S++KFLF GAGEA+LGIA+L+VM M E+G+ +E AR +I+LVDS+GL+V++RP GG+T  K +FA + EP++ L EIV+++ PT LIGA+   G FT ++L+ M   N +P+I ALSNPTSK+ECTAE+ YT T+G  +F+SGSPF+PV Y  +   PGQ NNAY+FPG+A  VI   I  I D +FL AAK L+  V+ ++LE G+++P +  I   SL +A  + E+A+++  A+  P+P D   F+ ++ Y+ NY+   +I KT
Sbjct:   66 NMVRGIDYLRDPRLNKGMAFSLEERQVLGLHGLIPPRFKTQEEQVDLCKKNVERYQEPLNKFIYLASLQDRNERLFYRLLSENVEEYMPIVYTPTVGLACQKFGLIFRRPRGLFISIHDKGHVYDVLRNWPEHDVRAIVVTDGERILGLGDLGVQGMGIPVGKLSLYTALAGIKPHQCLPIVLDVGTNRKELLEDEFYIGARHERVTGEAYDEFIDEFMHAVVQRYGQNTLIQFEDFGNHNAFRFLEKYRGKYCTFNDDIQGTASVAVAGLLASLRITDTKLSDHKFLFQGAGEASLGIANLIVMAMVEEGVDEEEARSKIWLVDSRGLIVKDRPKGGITGHKEVFAHEHEPMDDLEEIVRELQPTTLIGAAAIGGVFTPQLLQDMASFNERPVIFALSNPTSKAECTAEDCYTHTEGRGVFASGSPFDPVTYEGRTFHPGQGNNAYIFPGVALGVICTGIHHIDDGIFLMAAKALADMVTEENLEQGRLYPPLTDIQSCSLKIATYIAEHAYKTGIASTYPQPEDLTEFISEQMYDYNYDDNSAIPKT 614
[Close]
BLAST of Malic enzyme vs. TrEMBL
Match: E9GLD2 (Malic enzyme OS=Daphnia pulex OX=6669 GN=DAPPUDRAFT_304467 PE=3 SV=1)

HSP 1 Score: 591.267 bits (1523), Expect = 0.000e+0
Identity = 277/537 (51.58%), Postives = 382/537 (71.14%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G   I +  LNKG+ FT +ER+AL + G++P      ++Q +L L NLK  S +L KYIYLM L  +N +LF+ I S ++ +++P++YTPTVG AC KFG I+ +P GL+ISI DK +I  +L  WPE +V+AI VTDGERILGLGDLGA GMGIP+GKLALYT + G+ P  CLPI LD GTNT+ LL +  YIG + +R+ G+ Y+E +D FM   +  YG + LIQFEDFGNH AF FL+KYR  Y  FNDDIQGTASV VAGL+ ++R+   K++EN FLF GAGEA++GIA L+VM ++++G+  E A ++I+LVDSKGL+V++RP GG++  K  FA+   P+  L ++VKK+ P+VLIGA+   G+FT E++K M   N +P+I ALSNPTSK+ECTAE+AY  T G AIF+SGSPF PV Y  Q   PGQ NNAY+FPG+A AVI   I  I D +FL AA+ L+ +VS +DL  G+++P +  I + S+ +A  + E+A+++  A+  PEP DK+ F++ + Y+  Y+
Sbjct:    4 GIDYIRDPRLNKGMAFTLAERQALGIHGLIPPRFKTQEEQVELCLTNLKRYSEDLNKYIYLMGLQDRNERLFYRILSENVEDMMPIVYTPTVGLACQKFGVIYRRPRGLFISIHDKGHIYSMLRNWPEEDVRAIVVTDGERILGLGDLGAYGMGIPVGKLALYTALAGIKPHQCLPIVLDVGTNTQELLDDPLYIGLRQKRVTGDAYDELIDEFMTAVVHRYGQNTLIQFEDFGNHNAFRFLEKYRNKYLTFNDDIQGTASVAVAGLLASLRLTKTKLAENTFLFQGAGEASIGIAQLIVMALEKEGVPHEEALKKIWLVDSKGLLVKDRPEGGISGHKKEFAQDHPPMRHLSDVVKKIKPSVLIGAAAIGGAFTTEIIKDMASFNDRPVIFALSNPTSKAECTAEDAYKYTDGKAIFASGSPFLPVTYNGQTFYPGQGNNAYIFPGVALAVITTGIHHIKDDIFLMAAEALASRVSEQDLAEGRLYPPLGTIQECSIAIAAYIAEHAYKNGLASTYPEPADKEAFIKAQLYDFTYD 540
[Close]
BLAST of Malic enzyme vs. TrEMBL
Match: A0A0P5SBM6 (Malic enzyme OS=Daphnia magna OX=35525 PE=3 SV=1)

HSP 1 Score: 590.882 bits (1522), Expect = 0.000e+0
Identity = 277/537 (51.58%), Postives = 383/537 (71.32%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G   I +  LNKG+ FT +ER+AL + G++P      ++Q +L L NLK  + +L KYIYLM L  +N +LF+ I S ++ E++P++YTPTVG AC KFG I+ +P GL+ISI DK +I  +L  WPE +V+AI VTDGERILGLGDLGA GMGIP+GKLALYT + G+ P  CLPI LD GTNT+ LL +  YIG + +R+ G+ Y+E +D FM+  +  YG + LIQFEDFGNH AF FL+KYR  Y  FNDDIQGTASV VAGL+ ++R+   K++EN FLF GAGEA++GIA L+VM ++++G+  E A ++I+LVDSKGL+V++RP GG++  K  FA+   P+  L + VKK+ P+VLIGA+   G+FT E++K M   N +P+I ALSNPTSK+ECTAE+AY  T G AIF+SGSPF PV +  Q   PGQ NNAY+FPG+A AVI   I  I D++FL AA+ L+ +VS +DL  G+++P +  I D S  +A  + E+A+++  A+  PEP DK+ F++ + Y+ +Y+
Sbjct:   73 GIDYIRDPRLNKGMAFTLAERQALGIHGLIPPRFKTQEEQVELCLTNLKRYAEDLNKYIYLMGLQDRNERLFYRILSENVEEMMPIVYTPTVGLACQKFGVIYRRPRGLFISIHDKGHIYSMLRNWPEEDVRAIVVTDGERILGLGDLGAYGMGIPVGKLALYTALAGIKPHQCLPIVLDVGTNTQELLDDPLYIGLRHKRVTGDAYDELIDEFMQAVVHRYGQNTLIQFEDFGNHNAFRFLEKYRNKYLTFNDDIQGTASVAVAGLLASLRLTKTKLAENTFLFQGAGEASIGIAQLIVMALEKEGVPHEEALKKIWLVDSKGLLVKDRPEGGISGHKKEFAQDHPPMRHLADAVKKIRPSVLIGAAAIGGAFTPEIIKDMASFNDRPVIFALSNPTSKAECTAEDAYKYTDGKAIFASGSPFLPVTHNGQTFYPGQGNNAYIFPGVALAVITTGIHHIKDEIFLMAAEALASRVSEQDLAEGRLYPPLATIRDCSTAIAAYIAEHAYKNGLASTYPEPADKEAFIKAQLYDFSYD 609
[Close]
BLAST of Malic enzyme vs. TrEMBL
Match: A0A0P4XM76 (Malic enzyme OS=Daphnia magna OX=35525 PE=3 SV=1)

HSP 1 Score: 590.882 bits (1522), Expect = 0.000e+0
Identity = 277/537 (51.58%), Postives = 383/537 (71.32%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G   I +  LNKG+ FT +ER+AL + G++P      ++Q +L L NLK  + +L KYIYLM L  +N +LF+ I S ++ E++P++YTPTVG AC KFG I+ +P GL+ISI DK +I  +L  WPE +V+AI VTDGERILGLGDLGA GMGIP+GKLALYT + G+ P  CLPI LD GTNT+ LL +  YIG + +R+ G+ Y+E +D FM+  +  YG + LIQFEDFGNH AF FL+KYR  Y  FNDDIQGTASV VAGL+ ++R+   K++EN FLF GAGEA++GIA L+VM ++++G+  E A ++I+LVDSKGL+V++RP GG++  K  FA+   P+  L + VKK+ P+VLIGA+   G+FT E++K M   N +P+I ALSNPTSK+ECTAE+AY  T G AIF+SGSPF PV +  Q   PGQ NNAY+FPG+A AVI   I  I D++FL AA+ L+ +VS +DL  G+++P +  I D S  +A  + E+A+++  A+  PEP DK+ F++ + Y+ +Y+
Sbjct:   38 GIDYIRDPRLNKGMAFTLAERQALGIHGLIPPRFKTQEEQVELCLTNLKRYAEDLNKYIYLMGLQDRNERLFYRILSENVEEMMPIVYTPTVGLACQKFGVIYRRPRGLFISIHDKGHIYSMLRNWPEEDVRAIVVTDGERILGLGDLGAYGMGIPVGKLALYTALAGIKPHQCLPIVLDVGTNTQELLDDPLYIGLRHKRVTGDAYDELIDEFMQAVVHRYGQNTLIQFEDFGNHNAFRFLEKYRNKYLTFNDDIQGTASVAVAGLLASLRLTKTKLAENTFLFQGAGEASIGIAQLIVMALEKEGVPHEEALKKIWLVDSKGLLVKDRPEGGISGHKKEFAQDHPPMRHLADAVKKIRPSVLIGAAAIGGAFTPEIIKDMASFNERPVIFALSNPTSKAECTAEDAYKYTDGKAIFASGSPFLPVTHNGQTFYPGQGNNAYIFPGVALAVITTGIHHIKDEIFLMAAEALASRVSEQDLAEGRLYPPLATIRDCSTAIAAYIAEHAYKNGLASTYPEPADKEAFIKAQLYDFSYD 574
[Close]
BLAST of Malic enzyme vs. TrEMBL
Match: A0A0P5YQT9 (Malic enzyme OS=Daphnia magna OX=35525 PE=3 SV=1)

HSP 1 Score: 590.882 bits (1522), Expect = 0.000e+0
Identity = 277/537 (51.58%), Postives = 383/537 (71.32%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G   I +  LNKG+ FT +ER+AL + G++P      ++Q +L L NLK  + +L KYIYLM L  +N +LF+ I S ++ E++P++YTPTVG AC KFG I+ +P GL+ISI DK +I  +L  WPE +V+AI VTDGERILGLGDLGA GMGIP+GKLALYT + G+ P  CLPI LD GTNT+ LL +  YIG + +R+ G+ Y+E +D FM+  +  YG + LIQFEDFGNH AF FL+KYR  Y  FNDDIQGTASV VAGL+ ++R+   K++EN FLF GAGEA++GIA L+VM ++++G+  E A ++I+LVDSKGL+V++RP GG++  K  FA+   P+  L + VKK+ P+VLIGA+   G+FT E++K M   N +P+I ALSNPTSK+ECTAE+AY  T G AIF+SGSPF PV +  Q   PGQ NNAY+FPG+A AVI   I  I D++FL AA+ L+ +VS +DL  G+++P +  I D S  +A  + E+A+++  A+  PEP DK+ F++ + Y+ +Y+
Sbjct:    4 GIDYIRDPRLNKGMAFTLAERQALGIHGLIPPRFKTQEEQVELCLTNLKRYAEDLNKYIYLMGLQDRNERLFYRILSENVEEMMPIVYTPTVGLACQKFGVIYRRPRGLFISIHDKGHIYSMLRNWPEEDVRAIVVTDGERILGLGDLGAYGMGIPVGKLALYTALAGIKPHQCLPIVLDVGTNTQELLDDPLYIGLRHKRVTGDAYDELIDEFMQAVVHRYGQNTLIQFEDFGNHNAFRFLEKYRNKYLTFNDDIQGTASVAVAGLLASLRLTKTKLAENTFLFQGAGEASIGIAQLIVMALEKEGVPHEEALKKIWLVDSKGLLVKDRPEGGISGHKKEFAQDHPPMRHLADAVKKIRPSVLIGAAAIGGAFTPEIIKDMASFNERPVIFALSNPTSKAECTAEDAYKYTDGKAIFASGSPFLPVTHNGQTFYPGQGNNAYIFPGVALAVITTGIHHIKDEIFLMAAEALASRVSEQDLAEGRLYPPLATIRDCSTAIAAYIAEHAYKNGLASTYPEPADKEAFIKAQLYDFSYD 540
[Close]
BLAST of Malic enzyme vs. Ensembl Cavefish
Match: me1 (NADP-dependent malic enzyme [Source:NCBI gene;Acc:103030051])

HSP 1 Score: 529.635 bits (1363), Expect = 0.000e+0
Identity = 250/538 (46.47%), Postives = 356/538 (66.17%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY I  N  LNKG+ F+  ER  L + G+LP   L+ D Q    L+N + K  +L++Y++LM L  +N KLF+ + +  I   +P++YTPTVG AC  +G  F +P GL+I+I D+ +I  +L  WPE +++A+ VTDGERILGLGDLG  GMGIP+GKLALYT  GGV P +CLP+ LD GT+ + LL++  YIG +  R+ G  Y+E V+ FM+     YG D LIQFEDF N  AF  L KYR  Y  FNDDIQGTASV VAGL+ A+R+   KMS++  +F GAGEA +GIA L+ M M+++GLS     ++I++VDSKGL+V+ R    +T  K  FA +   +  L ++V+++ PT +IG +   G+FT  +++ M + N +PII ALSNPTSK+ECTAE+ YT T+G  IF+SGSPF+PV   + +   PGQ NNAYVFPG+   V  C ++ I + +FL  A+ +++ V+ KDL  G+++P +  I  VS  +A+ + EYA++ K A   PEP DK+ F++   +N NY+
Sbjct:   32 GYDITRNPHLNKGMAFSLEERLQLGIHGLLPPAFLSQDVQLLRVLRNYELKKDDLDRYVFLMGLQDRNEKLFYRVLTSDIERFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDRHHISTLLQSWPEKDIRAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVPPQHCLPVMLDVGTDNEELLKDPLYIGLRHRRVRGSAYDELVEEFMKAVTDRYGMDCLIQFEDFANVNAFRLLTKYRNKYLTFNDDIQGTASVAVAGLLAALRVTKSKMSDHTIVFQGAGEAAMGIAELIAMAMEKEGLSHAECLKKIWMVDSKGLIVKGRDH--LTAEKERFAHQHSQMRKLEDVVRELKPTAIIGVAAVAGAFTERIIRDMAEFNQRPIIFALSNPTSKAECTAEQCYTLTEGRGIFASGSPFDPVTLADGRRFYPGQGNNAYVFPGVGLGVTACAMRNISEDIFLITAETIAQMVTEKDLAEGRLYPPLPSIQHVSFKIAVKIVEYAYQHKIATHYPEPADKEAFVRSLIFNTNYD 567
[Close]
BLAST of Malic enzyme vs. Ensembl Cavefish
Match: me1 (NADP-dependent malic enzyme [Source:NCBI gene;Acc:103030051])

HSP 1 Score: 514.227 bits (1323), Expect = 1.390e-177
Identity = 242/525 (46.10%), Postives = 348/525 (66.29%), Query Frame = 1 
Query:   97 LGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            + F+  ER  L + G+LP   L+ D Q    L+N + K  +L++Y++LM L  +N KLF+ + +  I   +P++YTPTVG AC  +G  F +P GL+I+I D+ +I  +L  WPE +++A+ VTDGERILGLGDLG  GMGIP+GKLALYT  GGV P +CLP+ LD GT+ + LL++  YIG +  R+ G  Y+E V+ FM+     YG D LIQFEDF N  AF  L KYR  Y  FNDDIQGTASV VAGL+ A+R+   KMS++  +F GAGEA +GIA L+ M M+++GLS     ++I++VDSKGL+V+ R    +T  K  FA +   +  L ++V+++ PT +IG +   G+FT  +++ M + N +PII ALSNPTSK+ECTAE+ YT T+G  IF+SGSPF+PV   + +   PGQ NNAYVFPG+   V  C ++ I + +FL  A+ +++ V+ KDL  G+++P +  I  VS  +A+ + EYA++ K A   PEP DK+ F++   +N NY+
Sbjct:    1 MAFSLEERLQLGIHGLLPPAFLSQDVQLLRVLRNYELKKDDLDRYVFLMGLQDRNEKLFYRVLTSDIERFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDRHHISTLLQSWPEKDIRAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVPPQHCLPVMLDVGTDNEELLKDPLYIGLRHRRVRGSAYDELVEEFMKAVTDRYGMDCLIQFEDFANVNAFRLLTKYRNKYLTFNDDIQGTASVAVAGLLAALRVTKSKMSDHTIVFQGAGEAAMGIAELIAMAMEKEGLSHAECLKKIWMVDSKGLIVKGRDH--LTAEKERFAHQHSQMRKLEDVVRELKPTAIIGVAAVAGAFTERIIRDMAEFNQRPIIFALSNPTSKAECTAEQCYTLTEGRGIFASGSPFDPVTLADGRRFYPGQGNNAYVFPGVGLGVTACAMRNISEDIFLITAETIAQMVTEKDLAEGRLYPPLPSIQHVSFKIAVKIVEYAYQHKIATHYPEPADKEAFVRSLIFNTNYD 523
[Close]
BLAST of Malic enzyme vs. Ensembl Cavefish
Match: me3 (NADP-dependent malic enzyme-like [Source:NCBI gene;Acc:103029083])

HSP 1 Score: 504.982 bits (1299), Expect = 4.869e-173
Identity = 256/538 (47.58%), Postives = 361/538 (67.10%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY I  N  LNKG+ FT  ER  L + G+LP   L+ D Q    +K+ + + + L+KYI LM L  +N KLF+ + +  I E +P++YTPTVG AC ++G  F +P GL+I+I DK +I  +L  WPE ++KAI VTDGERILGLGDLG  GMGIP+GKLALYT  GGV P  CLP+ LD GT+ ++LL +  YIG K +R+ G++Y++ +D FM+     YG + LIQFEDF N  AF  L KYR  YC FNDDIQGTASV VAG++ A++I   K+S++KF+F GAGEA LGIA LL+M M ++G+    A +RI++VDSKGL+V+ R  G +   K  FA +   +++L E+V+ + PT +IG +   G+FT +++K M   N +PII ALSNPTSK+ECTAE+ Y  T+G  IF+SGSPF  V   + +   PGQ NNAYVFPG+A  VI C ++ I D +FL  A+ +S  V+ + L  G+++P +  I +VS  +A+ + +YA++ + A+  PEP DK+ F+    Y+ +Y+
Sbjct:   61 GYDITRNPHLNKGMAFTLEERLQLGIHGLLPPCFLSQDVQVLRVMKSYETRINPLDKYILLMTLQDRNEKLFYRLLTSDIEEFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDKGHIATMLNSWPEDDIKAIVVTDGERILGLGDLGGYGMGIPVGKLALYTACGGVPPQQCLPVLLDVGTDNETLLNDPLYIGLKHKRVRGKEYDDLIDEFMQAVTDKYGMNCLIQFEDFANSNAFRILNKYRNRYCTFNDDIQGTASVAVAGVLAALKITKNKLSDHKFVFQGAGEAALGIAHLLIMAMAKEGVPHAEAAKRIWMVDSKGLIVKGR--GHINHEKEEFAHEHPHIKTLEEVVETIKPTAIIGVAAIGGAFTEKIIKNMASFNERPIIFALSNPTSKAECTAEQCYKLTEGRGIFASGSPFQKVTLADGRTFYPGQGNNAYVFPGVALGVITCGVRHISDDIFLTTAEAISDMVTEEHLAEGRLYPPLSTIREVSFKIAVKIADYAYKQEIASWYPEPKDKEAFVLSNVYSPDYD 596
[Close]
BLAST of Malic enzyme vs. Ensembl Cavefish
Match: me2 (malic enzyme 2, NAD(+)-dependent, mitochondrial [Source:NCBI gene;Acc:445233])

HSP 1 Score: 485.337 bits (1248), Expect = 2.265e-166
Identity = 241/538 (44.80%), Postives = 341/538 (63.38%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++ N   NKG+ FT  ER+ L L G+LP  +   D Q   F +NL++ S  L+KYIYLM +  +N +LF+ +    I  ++P++YTPTVG AC ++G IF +P GL+ISI D+ ++  IL  WPE NVKA+ VTDGERILGLGDLG  GMGIP+GKL LYT   G+ P  CLP+ +D GT+ ++LL++ FY+G    R   + Y++ +D FME  ++ YG + LIQFEDFGNH AF FL+KYR  YC FNDDIQGTASV +AGL+ A R++ K ++++  LF GAGE                       RE+    + +  V    PS G  +            ++ L+ V  + PT +IG SG    FT +V+KTM  +N +PII ALSNPT+K+ECTAE+AYT T+G  +F+SGSPF PV   + Q+L PGQ NNAY+FPG+A AVI   ++ I D +FLEAAK L+ +++ ++L  G+++P +  I +VS+ +A+ V EY +    A   PEPVDK+ +++   +N NY+
Sbjct:   25 GKPLMLNPHTNKGMAFTLKERQMLGLQGLLPPKIETQDIQAMRFQRNLRKISDPLQKYIYLMGIQERNERLFYRVLMEDIEALMPIVYTPTVGLACTQYGHIFRRPKGLFISIMDRGHVRSILDNWPETNVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPESCLPVCIDVGTDNQTLLRDPFYMGLYRRRERSQAYDDLIDEFMEAVVQKYGQETLIQFEDFGNHNAFRFLKKYRHKYCTFNDDIQGTASVALAGLLAARRVVGKPITDHTVLFLGAGE----------------------DREQPTDSNQEAFV---HPSPGFGI------------KTFLDAVNILKPTAIIGVSGAGRLFTHDVIKTMGSLNERPIIFALSNPTAKAECTAEDAYTLTQGRCLFASGSPFGPVSLEDGQILTPGQGNNAYIFPGVALAVILSGVRHISDTVFLEAAKTLAGQLTDEELSQGRLYPPLSNIREVSVQMAIKVMEYLYMKGMAFQYPEPVDKEAYVRSTVWNTNYD 525
[Close]
BLAST of Malic enzyme vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003810.1 (pep scaffold:Pmarinus_7.0:GL476420:967784:1019810:1 gene:ENSPMAG00000003478.1 transcript:ENSPMAT00000003810.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 415.616 bits (1067), Expect = 8.010e-142
Identity = 194/401 (48.38%), Postives = 282/401 (70.32%), Query Frame = 1 
Query:   97 LGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKG 1299
            + F   ER+ L + G+LP   L+ D Q    +KN + ++++L++YI LM L  +N +LF+ +   ++   +P++YTPTVG AC ++G  F +P GL+I+I DK +I  +L  WPE++++A+ +TDGERILGLGDLG+ GMGIP+GKLALYT+ GGV P  CLP+ LD GT+ +SLL++ FYIG K +R+ G  Y+EF+D FM+  +  YG + LIQFEDF N  AF  L+KYR  YC FNDDIQGTA+V +AG++ A+R+   ++S++KFLF GAGEA +GIA LLVM M+ +G   + A  RI+++DSKGL++++R +  +T+ K  FA+    + +L E V  + PTVLIG +   G FT  +L+ M   N +PI+ ALSNPTSK+ECTAE+ Y +T+G
Sbjct:    1 MAFGLEERQHLGIHGLLPPCFLSQDVQVLHVIKNFERQTNDLDRYILLMGLQDRNERLFYKVLMSNVERFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDKGHIATVLKSWPESDIRAVVMTDGERILGLGDLGSYGMGIPVGKLALYTVCGGVQPQQCLPVMLDVGTDNQSLLEDPFYIGLKQKRVRGAAYDEFIDEFMQAIVNKYGKNCLIQFEDFANTNAFRLLRKYRDHYCTFNDDIQGTAAVALAGILAALRVTKNRLSDHKFLFQGAGEAAMGIAGLLVMGMEVEGTPRQKALSRIWMLDSKGLIIKSRDN--LTLEKKEFAQDHPAVTTLSEAVHTLRPTVLIGVAAIAGVFTEAILRDMASFNERPIVYALSNPTSKAECTAEQCYKATQG 399
[Close]
BLAST of Malic enzyme vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009618.1 (pep scaffold:Pmarinus_7.0:GL487013:196:1118:1 gene:ENSPMAG00000008692.1 transcript:ENSPMAT00000009618.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 123.25 bits (308), Expect = 9.568e-34
Identity = 55/109 (50.46%), Postives = 78/109 (71.56%), Query Frame = 1 
Query:  721 YGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENR 1047
            YG + LIQFEDFGNH AF  ++KYR  YC FNDDIQGTA+V +AG++ A ++    +S+++FLF GAGEA  GIA+L+VM + E G+    A  ++++ D  GL+V+ R
Sbjct:    5 YGYNTLIQFEDFGNHNAFRLMRKYREKYCTFNDDIQGTAAVALAGMLAAQKVTGTTLSQSRFLFLGAGEAATGIANLIVMALTEQGVPPVDAYGQVWMYDKHGLMVKVR 113
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BLAST of Malic enzyme vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001935.1 (pep scaffold:Pmarinus_7.0:GL490498:1324:3654:1 gene:ENSPMAG00000001760.1 transcript:ENSPMAT00000001935.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 121.709 bits (304), Expect = 8.123e-33
Identity = 58/126 (46.03%), Postives = 84/126 (66.67%), Query Frame = 1 
Query: 1291 TKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANY 1665
            T+G AIF+SGSPF  VK  + +V  PGQ NNAY+FPG A   I C ++ I D++FL +A+ L+ +V+ K L  G++FP ++ I DVS  +AL V E A+R   A++ PEPVDK+  +Q  F++  Y
Sbjct:    1 TQGQAIFASGSPFGEVKLADGRVFHPGQGNNAYIFPGAALGTIACGLRHIPDQIFLCSAQALAGQVTDKHLAEGRLFPPLNTIRDVSFNIALKVVEEAYRIGLASVLPEPVDKRALIQSHFFSPEY 126
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BLAST of Malic enzyme vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002089.1 (pep scaffold:Pmarinus_7.0:GL488934:952:2243:1 gene:ENSPMAG00000001897.1 transcript:ENSPMAT00000002089.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.219 bits (256), Expect = 3.013e-26
Identity = 48/126 (38.10%), Postives = 79/126 (62.70%), Query Frame = 1 
Query: 1294 KGAAIFSSGSPFNPVKY-GNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            +G  +F+SGSPF  V     ++L PGQ NNAYVFPG+A  VI  +++ I D+ FL  A+ ++ +V+   L  G+++P +  I D+S  +A+ + E A+ S  A+L PEP DK+  ++   Y+ +Y+
Sbjct:    1 QGRGVFASGSPFAAVSLPSGRMLHPGQGNNAYVFPGLALGVIAARVRHITDEAFLATAEMIAGEVTDAHLAEGRLYPPLSSIRDISFKIAVKIVEQAYASGMASLYPEPQDKEALVRSHVYSPDYD 126
[Close]
BLAST of Malic enzyme vs. Ensembl Yeast
Match: MAE1 (Mitochondrial malic enzyme; catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids [Source:SGD;Acc:S000001512])

HSP 1 Score: 337.035 bits (863), Expect = 6.124e-108
Identity = 195/528 (36.93%), Postives = 298/528 (56.44%), Query Frame = 1 
Query:   61 YKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIE-KILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPL-----ESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSK--KVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPV 1620
            ++++N+   NKG  FT+ ER+A  L  +LP  V  +D+Q +   K L    + L K  ++  L  +N  L+F +  RHI E++P+IYTPT G A   +   F KP G+++ I + D+IE ++ T   + +V  I V+D E ILG+GD G  G+ I I KLAL T+ GG+ P   LP+ LD GTN K L ++E Y+G K  RI G++Y++F++ F++   KVY + +L  FEDFG   A   L+KYR     FNDDIQGT +VV+A LI A++  ++ + + + L +GAG A LGIA  +V  M   G+  E AR++I+L+D +GL++++  +   T  + ++A+           SL ++V+ V PT L+G S Q G+FT +V++ M   N +PII  LSNPT   E    +    T   A+ ++GSPF PV  G ++    + NN Y FPGI    +  +   I DK+   A   L++   +   D   G + P +D I + S  +A AV   A    TA +  E V
Sbjct:  101 FQLLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSIECRLATYGGDKDVDYIVVSDSEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLPVCLDVGTNNKKLARDELYMGNKFSRIRGKQYDDFLEKFIKAVKKVYPSAVL-HFEDFGVKNARRLLEKYRYELPSFNDDIQGTGAVVMASLIAALKHTNRDLKDTRVLIYGAGSAGLGIADQIVNHMVTHGVDKEEARKKIFLMDRRGLILQSYEANS-TPAQHVYAKSDAEWAGINTRSLHDVVENVKPTCLVGCSTQAGAFTQDVVEEMHKHNPRPIIFPLSNPTRLHEAVPADLMKWTNNNALVATGSPFPPVD-GYRI---SENNNCYSFPGIGLGAVLSRATTITDKMISAAVDQLAELSPLREGDSRPG-LLPGLDTITNTSARLATAVILQALEEGTARIEQEQV 621
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BLAST of Malic enzyme vs. Ensembl Nematostella
Match: EDO33525 (Malic enzyme [Source:UniProtKB/TrEMBL;Acc:A7SRZ0])

HSP 1 Score: 522.316 bits (1344), Expect = 0.000e+0
Identity = 256/538 (47.58%), Postives = 373/538 (69.33%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKV-SSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANY 1665
            G  I+ ++ LNKGL FT  ER+ L + G+LP  V++ + Q +   + L+ K ++LEKYI LM L  +N  LFF +   +  E++P++YTPTVG AC K+G IF +P GL+ISI DK +I  I++ WP   VKAI +TDGERILGLGDLG  GMGIP+GKLALYT+ GG+DP  CLP+ +D GTN + LL + FYIG + +R   E Y+E +D F++  ++ +G   LIQFEDFGNH AF FL+KYR   C FNDDIQGTA+V VAG++ +++I   ++S+ + +F GAGEA +GIA+LLV+ M+++GL++E A+++I+LVDS+GLVV+ R  GG+T  K  FA++ E +++L ++VK + PT ++G +   G+FT E+ + M   N +P+I ALSNPTSK+ECTA   YT T+G  IF+SGSPF+PV   + +  +PGQ NNAY+FPG+A  VI C+   + D +FL AA+ +  ++ +   LE G ++P +  I +VS+ VAL+V + A+ S  A   PEP DK+  +++  Y  +Y
Sbjct:   15 GTDIMRDSHLNKGLAFTLEERQILGIHGLLPPCVISQEIQAQRVYRELQRKPNDLEKYIQLMALLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDKGHIRDIVSNWPTTEVKAIVMTDGERILGLGDLGCCGMGIPVGKLALYTVCGGIDPEGCLPVMIDVGTNNEELLDDPFYIGVRQKRCNTEDYDELIDEFIQAALQRFGPTTLIQFEDFGNHNAFRFLEKYRNKICTFNDDIQGTAAVAVAGVLASLKITKTRLSDQRIVFQGAGEAAIGIANLLVLAMKKEGLTEEQAKKKIWLVDSRGLVVKERDCGGLTEQKLAFAKEHEYIDNLTDVVKHIKPTTIVGVAAVPGAFTEEICRDMASFNDRPVIFALSNPTSKAECTALNCYTWTEGRGIFASGSPFDPVTLPDGRHFIPGQGNNAYIFPGLALGVIACEAAHVTDDMFLHAAEIMPPQILTDSQLEKGCLYPPLGDIREVSIKVALSVVKDAYSSGIACDMPEPEDKEELIRRHVYTPDY 552
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BLAST of Malic enzyme vs. Ensembl Nematostella
Match: EDO28487 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6B8])

HSP 1 Score: 231.491 bits (589), Expect = 1.212e-70
Identity = 109/220 (49.55%), Postives = 152/220 (69.09%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIK 717
            G  I+ ++ LNKGL FT  ER+ L + G+LP  V++ + Q +   + L+ K ++LEKYI LM L  +N  LFF +   +  E++P++YTPTVG AC K+G IF +P GL+ISI DK +I  I++ WP   VKAI +TDGERILGLGDLG  GMGIP+GKLALYT+ GG+DP  CLP+ +D GTN + LL + FYIG + +R   E Y+E +D F++  ++
Sbjct:   15 GTDIMRDSHLNKGLAFTLEERQILGIHGLLPPCVISQEIQAQRVYRELQRKPNDLEKYIQLMALLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDKGHIRDIVSNWPTTEVKAIVMTDGERILGLGDLGCCGMGIPVGKLALYTVCGGIDPEGCLPVMIDVGTNNEELLDDPFYIGVRQKRCNTEDYDELIDEFIQAALQ 234

HSP 2 Score: 128.257 bits (321), Expect = 1.473e-32
Identity = 58/124 (46.77%), Postives = 93/124 (75.00%), Query Frame = 1 
Query:  925 EATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTK 1296
            +A +GIA+LLV+ M+++GL++E A+++I+LVDS+GLVV++R  GG+T  K  FA++ E +++L ++VK + PT ++G +   G+FT E+ + M   N +P+I ALSNPTSK+ECTA   YT T+
Sbjct:  242 KAAIGIANLLVLAMKKEGLTEEQAKKKIWLVDSRGLVVKDRDCGGLTEQKLAFAKEHEYIDNLTDVVKHIKPTTIVGVAAVPGAFTEEICRDMASFNDRPVIFALSNPTSKAECTALNCYTWTE 365
[Close]
BLAST of Malic enzyme vs. Ensembl Medaka
Match: me2 (malic enzyme 2 [Source:NCBI gene;Acc:101168546])

HSP 1 Score: 536.569 bits (1381), Expect = 0.000e+0
Identity = 259/538 (48.14%), Postives = 358/538 (66.54%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++ N   NKG+ FT  ER+ L + G+LP  V   D Q   F KNLK+ +  LEKYIYLM +  +N +LF+ +    I E++P++YTPTVG AC ++G IF +P GL+ISI D+ ++  IL  WPE NV A+ VTDGERILGLGDLG  GMGIP+GKL LYT   G+ P  CLP+ +D GTN ++LL++ FY+G   +R   + Y++ +D FME  +  YG D LIQFEDFGNH AF FL+KYR  YC FNDDIQGTASV +AGL+ A R I K ++++K LF GAGEA LGIA+L+VM M E G++   A+E+I++ D+ GL+V+ R        ++        + S L+ V  + PT +IG +G    FT +V+K M   N +PII ALSNPT+K+ECTAEEAYT T G  +F+SGSPF PV   N QV  PGQ NNAY+FPG+A AVI   ++ I D +FLEAAK L+++++ ++L  G+++P +  I +VS+ +A+   EY +    A   PEP+DK  F++   +N +Y+
Sbjct:   27 GKPLMLNPHTNKGMAFTLQERQILGIHGLLPPKVETQDIQTLRFQKNLKKMTDPLEKYIYLMGIQERNERLFYRVLMEDIEELMPIVYTPTVGLACTQYGHIFRRPKGLFISILDRGHVRSILDNWPETNVSAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPEKCLPVVIDVGTNNETLLKDPFYMGLYQKRDRSQAYDDLIDEFMEAVVNKYGQDTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTASVALAGLLAAQRAIGKPITQHKLLFLGAGEAALGIANLIVMAMMEAGMTQAEAQEKIWMYDAHGLLVKGRSQKTDNNQEAFVHDSPGDVHSFLDAVNTIKPTAIIGVAGAGRLFTHDVIKVMGTFNERPIIFALSNPTNKAECTAEEAYTLTDGRCLFASGSPFGPVTLSNGQVFTPGQGNNAYIFPGVALAVILSGVRHISDTVFLEAAKALAEQLTDEELAEGRLYPPLSNIREVSVQIAIKAMEYVYSKGMAFRYPEPMDKNGFIRATVWNTSYD 564
[Close]
BLAST of Malic enzyme vs. Ensembl Medaka
Match: me1 (malic enzyme 1 [Source:NCBI gene;Acc:101159698])

HSP 1 Score: 530.406 bits (1365), Expect = 0.000e+0
Identity = 258/538 (47.96%), Postives = 369/538 (68.59%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY +  N  LNKG+ F+  ER  L + G+LP   ++ D Q    LKN   K  +L++Y++LM L  +N KLF+ + S H+   +P+IYTPTVG AC ++G IF +P GL+I+I D  +I  IL  WPE ++KA+CVTDGERILGLGDLG +GMGIP+GKLALYT  GG+ P  CLP+ LD GT+ ++LL++  Y+G + +R+ G+ Y++ +D FM+     YG D LIQFEDF N  AF  L KYR  YC FNDDIQGTA+V VAGL+ A+RI   KM ++  +F GAGEA +GIA L+ M M+++GLS E + ++I++VDSKGL+V+ R    +T  K  FA     +++L ++V+++ PT +IG +   G+F+ +++K M   N +PII ALSNPTSK+ECTAE+ YT T+G AIF+SGSPF+PV   + + L PGQ NNAY+FPG+  +V  C I+ I +++FL AA+ L+  V+ +DL  G+++P +  I DVSL +A  + EYA++   A+LRPEP DK  F++   +N  Y+
Sbjct:   32 GYDVTRNPNLNKGMAFSMEERLQLGIHGLLPPCFISQDVQLLRVLKNYDMKKDDLDRYVFLMGLQDRNEKLFYRLISSHVERFMPIIYTPTVGLACQQYGLIFRRPRGLFITIHDSGHIASILQNWPEKDIKAVCVTDGERILGLGDLGCHGMGIPVGKLALYTACGGMPPQQCLPVMLDVGTDNEALLKDPLYLGLRHKRVRGQPYDDLLDEFMKAVSDRYGMDCLIQFEDFANVNAFRLLSKYRNKYCTFNDDIQGTAAVAVAGLLAALRITKSKMCDHTIVFQGAGEAAMGIAELITMSMEKEGLSKEESLKKIWMVDSKGLIVKGRDH--LTHEKERFAHSHSQMKNLEDVVRELRPTAIIGVAAVPGAFSEQIIKDMASFNERPIIFALSNPTSKAECTAEQCYTLTEGRAIFASGSPFDPVTLPDGKTLYPGQGNNAYIFPGVGLSVTACAIRHITEEIFLTAAEALAHMVTERDLAEGRLYPPLSSIRDVSLKLAAKIIEYAYKHNIASLRPEPSDKDAFVRSLCFNTAYD 567
[Close]
BLAST of Malic enzyme vs. Ensembl Medaka
Match: me3 (NADP-dependent malic enzyme [Source:NCBI gene;Acc:101155546])

HSP 1 Score: 529.25 bits (1362), Expect = 0.000e+0
Identity = 254/538 (47.21%), Postives = 361/538 (67.10%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN-QVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            GY I  N +LNKG+ FT  ER  L + G+LP   L+ D Q    +K+ + +++ L+KYI LM L  +N KLF+ + +  I E +P++YTPTVG AC ++G  F +P GL+I+I D+ +I  +L  WP  N++AI VTDGERILGLGDLG+ GMGIP+GKLALYT  GGV P  CLP+ LD GT+ ++LL +  YIG K +RI G++Y+E +D FM+     YG + LIQFEDF N  AF  L KYR  YC FNDDIQGTASV VAG++ A++I   K+SE+ F+F GAGEA LGIA LL+M M ++G+S E A +RI++VDSKGL+V+ R    V   K+ FA     L++L E+V+ + PT +IG +   G+FT +++  M   N +PII ALSNPTSK+ECTAE+ Y  T+G  IF+SGSPF+ V   + +   PGQ NNAYVFPG+A  ++ C ++ I D +FL  A+ ++  V+ + L  G+++P +  I +VS  +A+ +  +A++   A+  PEP DK+ F+    Y+ +Y+
Sbjct:   76 GYDITRNPYLNKGMAFTLEERLQLGIHGLLPPCFLSQDVQVLRVMKSYEPRTNPLDKYILLMTLQDRNEKLFYRVLTSDIEEFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDRGHIATMLNSWPVQNIRAIVVTDGERILGLGDLGSYGMGIPVGKLALYTACGGVQPQQCLPVLLDVGTDNQALLDDPLYIGLKHKRIRGKEYDELIDEFMQAVTDKYGMNCLIQFEDFANSNAFRILNKYRNRYCTFNDDIQGTASVAVAGILAALKITKNKLSEHTFVFQGAGEAALGIAHLLIMAMAKEGVSPEEAAKRIWMVDSKGLIVKGRSH--VNHEKAEFAHDHPHLKTLEEVVQTIKPTAIIGVAAVGGAFTEKIITDMAAFNQRPIIFALSNPTSKAECTAEQCYKLTEGRGIFASGSPFSKVTLADGRTFYPGQGNNAYVFPGVALGIMACGVRHISDDIFLTTAEAIADMVTEEHLAEGRLYPPLSTIREVSFKIAVKIVNHAYKHNIASFYPEPKDKEAFVLSHVYSPDYD 611
[Close]
BLAST of Malic enzyme vs. Planmine SMEST
Match: SMESG000033377.1 (SMESG000033377.1)

HSP 1 Score: 1118.99 bits (2893), Expect = 0.000e+0
Identity = 549/553 (99.28%), Postives = 551/553 (99.64%), Query Frame = 1 
Query:   10 ISANFFFEIKMKNIGSGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            + A FFFEIKMKNIGSGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN+VLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE
Sbjct:   81 LQAYFFFEIKMKNIGSGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNEVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 633
[Close]
BLAST of Malic enzyme vs. Planmine SMEST
Match: SMESG000033377.1 (SMESG000033377.1)

HSP 1 Score: 1106.66 bits (2861), Expect = 0.000e+0
Identity = 542/543 (99.82%), Postives = 543/543 (100.00%), Query Frame = 1 
Query:   40 MKNIGSGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            MKNIGSGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGN+VLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE
Sbjct:    1 MKNIGSGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNEVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 543
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BLAST of Malic enzyme vs. Planmine SMEST
Match: SMESG000045895.1 (SMESG000045895.1)

HSP 1 Score: 516.153 bits (1328), Expect = 3.290e-178
Identity = 250/536 (46.64%), Postives = 359/536 (66.98%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANY 1665
            G  ++ +  +NKG  F   ER+ L + G+LP  V  +++Q    + NL++   +L ++++L+ L  +N  LF+ + + ++   LP+IYTPTVG AC K+G +F +P GLYI+I DK  I++IL  WPE  VKA+ V+DGERILGLGDLGA GMGIP+GKL+LYT + GV PS  LP+ LD GT+ + LL +  Y+G + +RI G+ Y +F+D FM+  ++ YG   LIQFEDF N  AF  L KYR  YC FNDDIQGTASV + GL+ A +I ++K+ +N FLF GAG A  GIA LL   + E G ++E A  +IY+ D  GL+V+ R     +   +IF + M+  + L E VK++ PTVLIGA+G  G F + +L  +     +PI+ ALSNPTSK+ECTA EAYT T G  I++ GSPF PV Y ++V +  Q NN+Y+FPGIA A+I  +I+P+ + LF+ AA+ L+K+VS +DL  G++FP++  I DVSL +A+++ EYAF +  AN  PEP DK+ ++ + +YN  Y
Sbjct:   19 GIDVLRDPRINKGTAFNLKERQLLGIHGLLPPGVNTMEEQALRCMINLRKIDDDLNRHLFLISLQDRNEDLFYKVVTDNVEYCLPIIYTPTVGLACQKYGLMFRRPRGLYITIHDKMYIKRILENWPEQIVKALVVSDGERILGLGDLGAYGMGIPVGKLSLYTALAGVPPSNTLPVLLDVGTDNQDLLDDPLYLGVRHKRIRGKMYFDFMDAFMQAVVEKYGRQCLIQFEDFANVNAFRILSKYRNDYCTFNDDIQGTASVTIGGLLGACKIANRKLKDNIFLFQGAGSAATGIALLLKRALIESGATEEEAISKIYMFDVDGLLVKTRSGVTFSPQNTIFVKDMKHHKILAEAVKEIKPTVLIGAAGVPGVFNSNILNMLTTFTDRPIVFALSNPTSKAECTAIEAYTHTDGKCIYACGSPFAPVHYKDKVFIASQCNNSYIFPGIALAIIMFQIRPVTEDLFIRAAETLAKQVSDEDLAQGRVFPALWTIKDVSLEIAVSIAEYAFSAGIANHHPEPKDKREYIMKHWYNPTY 554
[Close]
BLAST of Malic enzyme vs. Planmine SMEST
Match: SMESG000045895.1 (SMESG000045895.1)

HSP 1 Score: 513.072 bits (1320), Expect = 7.014e-177
Identity = 253/544 (46.51%), Postives = 362/544 (66.54%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENR------PSGGVTVF--KSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANY 1665
            G  ++ +  +NKG  F   ER+ L + G+LP  V  +++Q    + NL++   +L ++++L+ L  +N  LF+ + + ++   LP+IYTPTVG AC K+G +F +P GLYI+I DK  I++IL  WPE  VKA+ V+DGERILGLGDLGA GMGIP+GKL+LYT + GV PS  LP+ LD GT+ + LL +  Y+G + +RI G+ Y +F+D FM+  ++ YG   LIQFEDF N  AF  L KYR  YC FNDDIQGTASV + GL+ A +I ++K+ +N FLF GAG A  GIA LL   + E G ++E A  +IY+ D  GL+V++R         GVT     +IF + M+  + L E VK++ PTVLIGA+G  G F + +L  +     +PI+ ALSNPTSK+ECTA EAYT T G  I++ GSPF PV Y ++V +  Q NN+Y+FPGIA A+I  +I+P+ + LF+ AA+ L+K+VS +DL  G++FP++  I DVSL +A+++ EYAF +  AN  PEP DK+ ++ + +YN  Y
Sbjct:   19 GIDVLRDPRINKGTAFNLKERQLLGIHGLLPPGVNTMEEQALRCMINLRKIDDDLNRHLFLISLQDRNEDLFYKVVTDNVEYCLPIIYTPTVGLACQKYGLMFRRPRGLYITIHDKMYIKRILENWPEQIVKALVVSDGERILGLGDLGAYGMGIPVGKLSLYTALAGVPPSNTLPVLLDVGTDNQDLLDDPLYLGVRHKRIRGKMYFDFMDAFMQAVVEKYGRQCLIQFEDFANVNAFRILSKYRNDYCTFNDDIQGTASVTIGGLLGACKIANRKLKDNIFLFQGAGSAATGIALLLKRALIESGATEEEAISKIYMFDVDGLLVKHRDLDFQETRSGVTFSPQNTIFVKDMKHHKILAEAVKEIKPTVLIGAAGVPGVFNSNILNMLTTFTDRPIVFALSNPTSKAECTAIEAYTHTDGKCIYACGSPFAPVHYKDKVFIASQCNNSYIFPGIALAIIMFQIRPVTEDLFIRAAETLAKQVSDEDLAQGRVFPALWTIKDVSLEIAVSIAEYAFSAGIANHHPEPKDKREYIMKHWYNPTY 562
[Close]
BLAST of Malic enzyme vs. Planmine SMEST
Match: SMESG000026160.1 (SMESG000026160.1)

HSP 1 Score: 496.893 bits (1278), Expect = 1.332e-170
Identity = 251/537 (46.74%), Postives = 350/537 (65.18%), Query Frame = 1 
Query:   58 GYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLFLKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGTACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILGLGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFYIGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQKYRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLGIASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFARKMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMALSNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYVFPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIADVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE 1668
            G  ++     NK   FT  ER  L + G+LP  V  + +Q    + +LK+   +L+K+++L  L  +N  LF+ + + +I   +PLIYTPTVG AC K+G +F +  GLYI+I DK +I +IL  WP   +KAI VTDGERILGLGDLGA GMGIPIGKL+LYT + GV P Y LPI LD GTN + LL +  Y+G + ERI G  Y+EF+DIFM   I+ YG + LIQFEDFGN  A+  L KYR  YC FNDDIQGTASV +  L+ A +I  +K+ +NKFLF GAG A  GIA L+   +   G S++ A  RIY+ D  GL+ ++R     T     +A+ +   +SL E V  + PT +IG +G    FTA +L+ MK+    P I ALSNPTSKSEC+AEEAY +T+G  +F+SGSPF+PV        P Q NN+Y+FPGIA A+I  KI+PI  ++F+ AA+ L+  +S +++  G+IFPS+D I +VS+ +A+AV EYA++ + +N  PEP++K+ F+++  ++  Y 
Sbjct:   27 GVDVLRAPEFNKDTAFTIKERHLLGIHGLLPPAVDTLSEQSVRTMISLKKSGDDLQKHLFLTSLMERNEVLFYKVITDNIEYCMPLIYTPTVGLACQKYGLMFRRSRGLYITIHDKMHIRQILNNWPSDIIKAIVVTDGERILGLGDLGAYGMGIPIGKLSLYTALAGVPPRYTLPILLDVGTNNEELLDDPMYLGLRHERIRGAAYDEFLDIFMANVIEKYGRNTLIQFEDFGNVNAYRILNKYRDKYCTFNDDIQGTASVCLGALLGAEKISKRKLQDNKFLFQGAGSAATGIAELISKALMNRGDSEDEAISRIYMFDIDGLLTKSRRKSTFTTENIKYAKDLSETKSLEEAVNLIKPTAIIGVAGVGQVFTAPILRKMKETVDVPYIFALSNPTSKSECSAEEAYKNTEGKCVFASGSPFDPVDLDQTRYYPTQCNNSYIFPGIALAIILFKIRPITIEMFVIAAETLASLISEEEIVNGRIFPSLDSIKNVSISIAIAVAEYAYKVQLSNRIPEPLNKEKFIKKYMFSPKYR 563
The following BLAST results are available for this feature:
BLAST of Malic enzyme vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ME10.000e+049.07malic enzyme 1 [Source:HGNC Symbol;Acc:HGNC:6983][more]
ME31.493e-18047.03malic enzyme 3 [Source:HGNC Symbol;Acc:HGNC:6985][more]
ME31.493e-18047.03malic enzyme 3 [Source:HGNC Symbol;Acc:HGNC:6985][more]
ME31.187e-17947.28malic enzyme 3 [Source:HGNC Symbol;Acc:HGNC:6985][more]
ME21.784e-17446.85malic enzyme 2 [Source:HGNC Symbol;Acc:HGNC:6984][more]
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BLAST of Malic enzyme vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
men-16.181e-16945.93Malic enzyme [Source:UniProtKB/TrEMBL;Acc:Q9U296][more]
men-16.181e-16945.93Malic enzyme [Source:UniProtKB/TrEMBL;Acc:Q9U296][more]
men-16.181e-16945.93Malic enzyme [Source:UniProtKB/TrEMBL;Acc:Q9U296][more]
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BLAST of Malic enzyme vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Men0.000e+049.91gene:FBgn0002719 transcript:FBtr0082661[more]
Men0.000e+049.91gene:FBgn0002719 transcript:FBtr0082660[more]
Men0.000e+049.54gene:FBgn0002719 transcript:FBtr0330025[more]
Men-b0.000e+049.35gene:FBgn0029155 transcript:FBtr0301707[more]
Men-b0.000e+049.35gene:FBgn0029155 transcript:FBtr0301708[more]
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BLAST of Malic enzyme vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
me20.000e+047.96malic enzyme 2, NAD(+)-dependent, mitochondrial [S... [more]
me20.000e+047.96malic enzyme 2, NAD(+)-dependent, mitochondrial [S... [more]
me31.342e-17347.77malic enzyme 3, NADP(+)-dependent, mitochondrial [... [more]
me13.470e-17145.72malic enzyme 1, NADP(+)-dependent, cytosolic [Sour... [more]
me17.034e-17145.72malic enzyme 1, NADP(+)-dependent, cytosolic [Sour... [more]
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BLAST of Malic enzyme vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abhd40.000e+047.40abhydrolase domain containing 4 [Source:Xenbase;Ac... [more]
abhd40.000e+047.40abhydrolase domain containing 4 [Source:Xenbase;Ac... [more]
slc38a70.000e+047.96solute carrier family 38 member 7 [Source:Xenbase;... [more]
slc38a70.000e+047.96solute carrier family 38 member 7 [Source:Xenbase;... [more]
slc38a70.000e+047.96solute carrier family 38 member 7 [Source:Xenbase;... [more]
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BLAST of Malic enzyme vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Me10.000e+050.37malic enzyme 1, NADP(+)-dependent, cytosolic [Sour... [more]
Me10.000e+050.67malic enzyme 1, NADP(+)-dependent, cytosolic [Sour... [more]
Me20.000e+047.68malic enzyme 2, NAD(+)-dependent, mitochondrial [S... [more]
Me30.000e+047.03malic enzyme 3, NADP(+)-dependent, mitochondrial [... [more]
Me31.106e-1141.38malic enzyme 3, NADP(+)-dependent, mitochondrial [... [more]
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BLAST of Malic enzyme vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P13697|MAOX_RAT0.000e+050.93NADP-dependent malic enzyme OS=Rattus norvegicus O... [more]
sp|P06801|MAOX_MOUSE0.000e+050.37NADP-dependent malic enzyme OS=Mus musculus OX=100... [more]
sp|P37223|MAOX_MESCR0.000e+049.36NADP-dependent malic enzyme OS=Mesembryanthemum cr... [more]
sp|P28227|MAOX_ANAPL0.000e+049.35NADP-dependent malic enzyme OS=Anas platyrhynchos ... [more]
sp|P40927|MAOX_COLLI0.000e+049.35NADP-dependent malic enzyme OS=Columba livia OX=89... [more]
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BLAST of Malic enzyme vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A423T5V20.000e+051.00Malic enzyme OS=Penaeus vannamei OX=6689 GN=C7M84_... [more]
E9GLD20.000e+051.58Malic enzyme OS=Daphnia pulex OX=6669 GN=DAPPUDRAF... [more]
A0A0P5SBM60.000e+051.58Malic enzyme OS=Daphnia magna OX=35525 PE=3 SV=1[more]
A0A0P4XM760.000e+051.58Malic enzyme OS=Daphnia magna OX=35525 PE=3 SV=1[more]
A0A0P5YQT90.000e+051.58Malic enzyme OS=Daphnia magna OX=35525 PE=3 SV=1[more]
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BLAST of Malic enzyme vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
me10.000e+046.47NADP-dependent malic enzyme [Source:NCBI gene;Acc:... [more]
me11.390e-17746.10NADP-dependent malic enzyme [Source:NCBI gene;Acc:... [more]
me34.869e-17347.58NADP-dependent malic enzyme-like [Source:NCBI gene... [more]
me22.265e-16644.80malic enzyme 2, NAD(+)-dependent, mitochondrial [S... [more]
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BLAST of Malic enzyme vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000003810.18.010e-14248.38pep scaffold:Pmarinus_7.0:GL476420:967784:1019810:... [more]
ENSPMAT00000009618.19.568e-3450.46pep scaffold:Pmarinus_7.0:GL487013:196:1118:1 gene... [more]
ENSPMAT00000001935.18.123e-3346.03pep scaffold:Pmarinus_7.0:GL490498:1324:3654:1 gen... [more]
ENSPMAT00000002089.13.013e-2638.10pep scaffold:Pmarinus_7.0:GL488934:952:2243:1 gene... [more]
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BLAST of Malic enzyme vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
MAE16.124e-10836.93Mitochondrial malic enzyme; catalyzes the oxidativ... [more]
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BLAST of Malic enzyme vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO335250.000e+047.58Malic enzyme [Source:UniProtKB/TrEMBL;Acc:A7SRZ0][more]
EDO284871.212e-7049.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Malic enzyme vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
me20.000e+048.14malic enzyme 2 [Source:NCBI gene;Acc:101168546][more]
me10.000e+047.96malic enzyme 1 [Source:NCBI gene;Acc:101159698][more]
me30.000e+047.21NADP-dependent malic enzyme [Source:NCBI gene;Acc:... [more]
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BLAST of Malic enzyme vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000033377.10.000e+099.28SMESG000033377.1[more]
SMESG000033377.10.000e+099.82SMESG000033377.1[more]
SMESG000045895.13.290e-17846.64SMESG000045895.1[more]
SMESG000045895.17.014e-17746.51SMESG000045895.1[more]
SMESG000026160.11.332e-17046.74SMESG000026160.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007159 ID=SMED30007159|Name=Malic enzyme|organism=Schmidtea mediterranea sexual|type=transcript|length=1766bp
TAATAATCAATTTCAGCTAATTTTTTCTTTGAAATTAAAATGAAAAATAT
TGGAAGTGGTTACAAAATAATAAATAATAATTTTTTGAATAAGGGTCTAG
GGTTTACAGAATCCGAAAGGAAGGCTCTGTTGTTGACTGGGATTTTACCT
CAATTGGTGTTGAACATAGACCAACAAGAGAAATTGTTCCTTAAAAATCT
TAAGGAAAAATCCAGCAATCTAGAAAAATATATTTACCTAATGGATTTAC
ACTCAAAAAATATTAAATTATTTTTTTATATCGCCTCTCGTCATATTTCG
GAAATTTTACCATTAATTTATACCCCAACTGTTGGCACGGCCTGCCTTAA
ATTCGGTGAAATTTTCACTAAACCGTGCGGACTTTATATATCAATCAAGG
ACAAAGATAACATAGAAAAGATTTTAACGATGTGGCCTGAAGCAAATGTT
AAAGCAATTTGTGTGACCGATGGTGAAAGAATATTAGGATTAGGAGATTT
GGGAGCTAACGGAATGGGCATACCAATTGGGAAGTTGGCATTATATACAA
TGATTGGAGGAGTGGACCCTTCCTACTGTCTGCCAATTACTTTGGATGCC
GGTACAAATACAAAGAGTCTCCTTCAAAATGAATTTTATATTGGACAAAA
AATGGAGAGAATTATTGGAGAAAAGTATGAAGAATTCGTAGATATCTTTA
TGGAAATATGTATAAAAGTATATGGTGCAGATCTTCTCATTCAATTCGAA
GACTTTGGCAATCATTATGCTTTTCATTTTCTGCAAAAATATCGCATGAC
ATATTGCATGTTTAATGATGATATACAAGGAACTGCATCTGTTGTCGTGG
CAGGTTTGATTAACGCAATCAGAATTATTGATAAAAAAATGTCTGAAAAT
AAATTTTTATTTTTTGGTGCCGGTGAAGCAACACTAGGAATAGCCAGTTT
ACTTGTTATGATCATGCAGGAAGATGGGTTAAGTGATGAAGGAGCAAGAG
AAAGAATTTATTTGGTGGATTCTAAAGGCTTAGTAGTTGAAAATCGGCCA
AGTGGAGGAGTTACAGTGTTCAAAAGTATTTTCGCCAGAAAAATGGAACC
GTTAGAGTCTTTGTTAGAGATAGTAAAAAAGGTTTCACCGACGGTATTAA
TTGGAGCTTCTGGTCAAAAAGGATCTTTTACTGCAGAAGTATTGAAAACA
ATGAAAGACATAAACAGTAAACCTATAATTATGGCTCTTAGCAATCCAAC
CTCTAAATCGGAATGTACAGCGGAGGAGGCCTATACGAGCACAAAGGGAG
CAGCTATTTTTTCAAGTGGTAGTCCATTTAATCCAGTAAAATATGGCAAT
CAGGTTTTACTACCGGGTCAAGCAAATAATGCTTACGTTTTCCCTGGGAT
CGCATTTGCTGTCATACACTGTAAAATTAAGCCAATACATGATAAATTAT
TTCTTGAAGCAGCTAAAGGTCTCTCTAAAAAAGTGAGTTCGAAAGATTTG
GAAATGGGTAAAATATTTCCGAGCATGGATCAAATAGCTGATGTTTCCCT
TGGAGTGGCATTGGCTGTCTGTGAATATGCATTTCGTTCAAAGACTGCGA
ATTTGCGACCGGAACCTGTGGACAAAAAATTATTTCTCCAACAAAAGTTT
TACAATGCAAATTACGAATAACTCAGAAGTATCTGAAAAACCCATTTTGA
AAAATATTTATTGCTTAGAACTTATTAAACGTAATGCCGTAATTAATAAT
ATTTTTTTCAAAGGCC
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protein sequence of SMED30007159-orf-1

>SMED30007159-orf-1 ID=SMED30007159-orf-1|Name=SMED30007159-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=544bp
MKNIGSGYKIINNNFLNKGLGFTESERKALLLTGILPQLVLNIDQQEKLF
LKNLKEKSSNLEKYIYLMDLHSKNIKLFFYIASRHISEILPLIYTPTVGT
ACLKFGEIFTKPCGLYISIKDKDNIEKILTMWPEANVKAICVTDGERILG
LGDLGANGMGIPIGKLALYTMIGGVDPSYCLPITLDAGTNTKSLLQNEFY
IGQKMERIIGEKYEEFVDIFMEICIKVYGADLLIQFEDFGNHYAFHFLQK
YRMTYCMFNDDIQGTASVVVAGLINAIRIIDKKMSENKFLFFGAGEATLG
IASLLVMIMQEDGLSDEGARERIYLVDSKGLVVENRPSGGVTVFKSIFAR
KMEPLESLLEIVKKVSPTVLIGASGQKGSFTAEVLKTMKDINSKPIIMAL
SNPTSKSECTAEEAYTSTKGAAIFSSGSPFNPVKYGNQVLLPGQANNAYV
FPGIAFAVIHCKIKPIHDKLFLEAAKGLSKKVSSKDLEMGKIFPSMDQIA
DVSLGVALAVCEYAFRSKTANLRPEPVDKKLFLQQKFYNANYE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR037062Malic_N_dom_sf
IPR036291NAD(P)-bd_dom_sf
IPR001891Malic_OxRdtase
IPR012302Malic_NAD-bd
IPR012301Malic_N_dom
IPR016040NAD(P)-bd_dom
IPR015884Malic_enzyme_CS
Vocabulary: biological process
TermDefinition
GO:0006108malate metabolic process
GO:0055114oxidation-reduction process
Vocabulary: molecular function
TermDefinition
GO:0004470malic enzyme activity
GO:0051287NAD binding
GO:0004471malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0016491oxidoreductase activity
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001891Malic oxidoreductasePRINTSPR00072MALOXRDTASEcoord: 289..305
score: 58.38
coord: 137..166
score: 72.83
coord: 77..101
score: 45.4
coord: 173..195
score: 57.83
coord: 233..251
score: 59.87
coord: 258..274
score: 77.65
coord: 392..408
score: 64.56
IPR001891Malic oxidoreductasePIRSFPIRSF000106MEcoord: 1..543
e-value: 1.1E-199
score: 662.4
IPR012301Malic enzyme, N-terminal domainSMARTSM01274malic_2coord: 71..252
e-value: 2.2E-83
score: 293.0
IPR012301Malic enzyme, N-terminal domainPFAMPF00390maliccoord: 72..252
e-value: 4.3E-69
score: 232.0
IPR012302Malic enzyme, NAD-bindingSMARTSM00919Malic_M_2coord: 262..515
e-value: 3.5E-92
score: 322.2
IPR012302Malic enzyme, NAD-bindingPFAMPF03949Malic_Mcoord: 262..514
e-value: 1.8E-89
score: 299.4
IPR037062Malic enzyme, N-terminal domain superfamilyGENE3DG3DSA:3.40.50.10380coord: 5..259
e-value: 3.5E-104
score: 349.4
NoneNo IPR availableGENE3DG3DSA:3.40.50.720coord: 260..543
e-value: 1.8E-107
score: 361.1
NoneNo IPR availablePANTHERPTHR23406MALIC ENZYME-RELATEDcoord: 6..542
NoneNo IPR availablePANTHERPTHR23406:SF34MALIC ENZYMEcoord: 6..542
NoneNo IPR availableCDDcd05312NAD_bind_1_malic_enzcoord: 262..539
e-value: 1.1847E-125
score: 367.259
NoneNo IPR availableSUPERFAMILYSSF53223Aminoacid dehydrogenase-like, N-terminal domaincoord: 6..261
IPR015884Malic enzyme, conserved sitePROSITEPS00331MALIC_ENZYMEScoord: 258..274
IPR036291NAD(P)-binding domain superfamilySUPERFAMILYSSF51735NAD(P)-binding Rossmann-fold domainscoord: 262..542