RING-type domain-containing protein

Overview
NameRING-type domain-containing protein
Smed IDSMED30007147
Length (bp)742
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of RING-type domain-containing protein (SMED30007147) t-SNE clustered cells

Violin plots show distribution of expression levels for RING-type domain-containing protein (SMED30007147) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RING-type domain-containing protein (SMED30007147) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RING-type domain-containing protein (SMED30007147) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30007147

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30007147SMESG000075014.1 SmedASXL_013592SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30007147SMESG000075014.1 SmedASXL_013592SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30007147SMESG000075014.1 dd_Smed_v4_6297_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30007147SMESG000075014.1 dd_Smed_v4_6297_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30007147SMESG000075014.1 dd_Smed_v4_6297_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30007147SMESG000075014.1 dd_Smed_v4_6297_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30007147SMESG000075014.1 dd_Smed_v4_6297_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30007147SMESG000075014.1 OX_Smed_1.0.19767ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF41 (ring finger protein 41 [Source:HGNC Symbol;Acc:HGNC:18401])

HSP 1 Score: 66.6254 bits (161), Expect = 9.723e-13
Identity = 31/101 (30.69%), Postives = 51/101 (50.50%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            + E LIC IC  V  +P     C H FC  C+T W +  ++CP DR+ VT+         + +++  L+I+C    +GC  + R   +  H+  C+ NP +
Sbjct:   12 VDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF41 (ring finger protein 41 [Source:HGNC Symbol;Acc:HGNC:18401])

HSP 1 Score: 65.855 bits (159), Expect = 1.211e-12
Identity = 31/101 (30.69%), Postives = 51/101 (50.50%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            + E LIC IC  V  +P     C H FC  C+T W +  ++CP DR+ VT+         + +++  L+I+C    +GC  + R   +  H+  C+ NP +
Sbjct:   12 VDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: PDZRN4 (PDZ domain containing ring finger 4 [Source:HGNC Symbol;Acc:HGNC:30552])

HSP 1 Score: 67.781 bits (164), Expect = 2.255e-12
Identity = 31/102 (30.39%), Postives = 47/102 (46.08%), Query Frame = 3 
Query:  135 LICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFA---------LADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            L C++C  V  +P C  CGH FC +C+  W    + CP       L C+  A         L  +I  L + C +R  GCG+  R + ++ H+  C F P +
Sbjct:   16 LECKLCGQVLEEPLCTPCGHVFCASCLLPWAVRRRRCP-------LQCQPLAPGELYRVLPLRSLIQKLRVQCDYRARGCGHSVRLHELEAHVEHCDFGPAR 110
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF41 (ring finger protein 41 [Source:HGNC Symbol;Acc:HGNC:18401])

HSP 1 Score: 66.2402 bits (160), Expect = 3.580e-12
Identity = 31/101 (30.69%), Postives = 51/101 (50.50%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            + E LIC IC  V  +P     C H FC  C+T W +  ++CP DR+ VT+         + +++  L+I+C    +GC  + R   +  H+  C+ NP +
Sbjct:   12 VDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF41 (ring finger protein 41 [Source:HGNC Symbol;Acc:HGNC:18401])

HSP 1 Score: 66.2402 bits (160), Expect = 3.580e-12
Identity = 31/101 (30.69%), Postives = 51/101 (50.50%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            + E LIC IC  V  +P     C H FC  C+T W +  ++CP DR+ VT+         + +++  L+I+C    +GC  + R   +  H+  C+ NP +
Sbjct:   12 VDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: elgi (gene:FBgn0283649 transcript:FBtr0075510)

HSP 1 Score: 68.9366 bits (167), Expect = 2.133e-13
Identity = 35/105 (33.33%), Postives = 50/105 (47.62%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDPW-CLSCGHTFCRTCVTTWLASNKSCPTDRTKVT---LCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDP 422
            ++ E L C IC  V  DP   + C H FCR C+  WL    +CP DR  +T   L      L +++  L I+C   PYGC  + +      H+ +C  NP +  P
Sbjct:   11 EVDEELTCPICSGVLEDPLQAVMCEHAFCRGCINEWLTRQPTCPVDRNSLTTANLRAVPRILRNLLSRLSITCDNAPYGCTAVLKLDAYNSHLDECIHNPKRPFP 115
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: elgi (gene:FBgn0283649 transcript:FBtr0333573)

HSP 1 Score: 68.9366 bits (167), Expect = 2.133e-13
Identity = 35/105 (33.33%), Postives = 50/105 (47.62%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDPW-CLSCGHTFCRTCVTTWLASNKSCPTDRTKVT---LCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDP 422
            ++ E L C IC  V  DP   + C H FCR C+  WL    +CP DR  +T   L      L +++  L I+C   PYGC  + +      H+ +C  NP +  P
Sbjct:   11 EVDEELTCPICSGVLEDPLQAVMCEHAFCRGCINEWLTRQPTCPVDRNSLTTANLRAVPRILRNLLSRLSITCDNAPYGCTAVLKLDAYNSHLDECIHNPKRPFP 115
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: CG9014 (gene:FBgn0028847 transcript:FBtr0343664)

HSP 1 Score: 65.855 bits (159), Expect = 3.114e-12
Identity = 45/164 (27.44%), Postives = 75/164 (45.73%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDPWCLS-CGHTFCRTCVTTWLASNKSCPTDRTKVT---LCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTPPAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYM 602
            + E LIC IC DV  +P   S C H FCR C+  W+   + CP DR+ +    L   +  + +++  L+I C++   GC  +      + H+  C+ NP     V+ E  +   +  P  + ++ +    L EL+ +L    V D       +EE S + R  M
Sbjct:   12 VDEELICPICTDVLEEPVQSSECEHAFCRACIDKWMIQKQICPVDRSGLLTSHLVPVSRLMRNMLSRLKIKCTFSQSGCAQMLALEEFRTHVAACEHNPK----VVVECSKGCGMKVPKDEMSRHNCVFELRELVEKLAKE-VSDLKQKQSDMEEQSSSQRREM 170
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: CG9014 (gene:FBgn0028847 transcript:FBtr0080579)

HSP 1 Score: 65.855 bits (159), Expect = 3.114e-12
Identity = 45/164 (27.44%), Postives = 75/164 (45.73%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDPWCLS-CGHTFCRTCVTTWLASNKSCPTDRTKVT---LCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTPPAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYM 602
            + E LIC IC DV  +P   S C H FCR C+  W+   + CP DR+ +    L   +  + +++  L+I C++   GC  +      + H+  C+ NP     V+ E  +   +  P  + ++ +    L EL+ +L    V D       +EE S + R  M
Sbjct:   12 VDEELICPICTDVLEEPVQSSECEHAFCRACIDKWMIQKQICPVDRSGLLTSHLVPVSRLMRNMLSRLKIKCTFSQSGCAQMLALEEFRTHVAACEHNPK----VVVECSKGCGMKVPKDEMSRHNCVFELRELVEKLAKE-VSDLKQKQSDMEEQSSSQRREM 170
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: CG13605 (gene:FBgn0039150 transcript:FBtr0300705)

HSP 1 Score: 56.225 bits (134), Expect = 8.530e-9
Identity = 22/44 (50.00%), Postives = 26/44 (59.09%), Query Frame = 3 
Query:  138 ICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVT 269
            +C IC D FN P  L CGH FC  CV TW    ++CP  R KV+
Sbjct:  609 LCPICHDAFNTPTVLECGHIFCDECVQTWFKREQTCPMCRAKVS 652
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: traf7 (TNF receptor-associated factor 7 [Source:ZFIN;Acc:ZDB-GENE-070112-2212])

HSP 1 Score: 75.485 bits (184), Expect = 3.634e-15
Identity = 45/129 (34.88%), Postives = 63/129 (48.84%), Query Frame = 3 
Query:   66 FQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSW--RPYGCGYIGRYYI-------------VKDHIVKCKFNP 407
               + E  E +++ + P   S  L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D +K+T+   N A+A+ IG+L I C +  RP   G  G Y +              KDH V C + P
Sbjct:   78 LHEEEEDTEPQVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNSKLTVVVNNIAVAEQIGELFIHCKYGCRPAASGKSGAYEVDPLGCPFTIKLSTRKDHEVSCDYRP 199
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: traf7 (TNF receptor-associated factor 7 [Source:ZFIN;Acc:ZDB-GENE-070112-2212])

HSP 1 Score: 75.485 bits (184), Expect = 3.634e-15
Identity = 45/129 (34.88%), Postives = 63/129 (48.84%), Query Frame = 3 
Query:   66 FQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSW--RPYGCGYIGRYYI-------------VKDHIVKCKFNP 407
               + E  E +++ + P   S  L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D +K+T+   N A+A+ IG+L I C +  RP   G  G Y +              KDH V C + P
Sbjct:   78 LHEEEEDTEPQVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNSKLTVVVNNIAVAEQIGELFIHCKYGCRPAASGKSGAYEVDPLGCPFTIKLSTRKDHEVSCDYRP 199
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: traf7 (TNF receptor-associated factor 7 [Source:ZFIN;Acc:ZDB-GENE-070112-2212])

HSP 1 Score: 75.485 bits (184), Expect = 3.897e-15
Identity = 45/129 (34.88%), Postives = 63/129 (48.84%), Query Frame = 3 
Query:   66 FQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSW--RPYGCGYIGRYYI-------------VKDHIVKCKFNP 407
               + E  E +++ + P   S  L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D +K+T+   N A+A+ IG+L I C +  RP   G  G Y +              KDH V C + P
Sbjct:  104 LHEEEEDTEPQVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNSKLTVVVNNIAVAEQIGELFIHCKYGCRPAASGKSGAYEVDPLGCPFTIKLSTRKDHEVSCDYRP 225
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: rnf41 (ring finger protein 41 [Source:NCBI gene;Acc:406837])

HSP 1 Score: 68.1662 bits (165), Expect = 5.516e-13
Identity = 34/102 (33.33%), Postives = 51/102 (50.00%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            ++ E L+C IC  V  +P     C H FC  C+T W A  + CP DRT VTL         + +++  L+ISC    +GC    R   ++ H+  C+ NP +
Sbjct:   11 EVDEDLLCPICSGVLEEPVQAPHCEHAFCNACITQWFAQQQICPVDRTVVTLAHLRPVPRIMRNMLSKLQISCDNAGFGCTATLRLDQLQSHLKDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: rnf41 (ring finger protein 41 [Source:NCBI gene;Acc:406837])

HSP 1 Score: 68.1662 bits (165), Expect = 5.516e-13
Identity = 34/102 (33.33%), Postives = 51/102 (50.00%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            ++ E L+C IC  V  +P     C H FC  C+T W A  + CP DRT VTL         + +++  L+ISC    +GC    R   ++ H+  C+ NP +
Sbjct:   11 EVDEDLLCPICSGVLEEPVQAPHCEHAFCNACITQWFAQQQICPVDRTVVTLAHLRPVPRIMRNMLSKLQISCDNAGFGCTATLRLDQLQSHLKDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:100216042])

HSP 1 Score: 69.3218 bits (168), Expect = 5.139e-13
Identity = 41/126 (32.54%), Postives = 59/126 (46.83%), Query Frame = 3 
Query:   75 KSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
            + E+  D + F +   +   L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D  K+T+   N A+A+ IG+L I C +                P GC +  +    KDH   C + P
Sbjct:  107 EEEEEPDPLVFAEQPSVK--LCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNAKLTVVVNNIAVAEQIGELFIHCKYGCHPSSNGKPVTFEVDPRGCPFTIKLSARKDHEGSCDYRP 226
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:100216042])

HSP 1 Score: 69.3218 bits (168), Expect = 5.323e-13
Identity = 41/126 (32.54%), Postives = 59/126 (46.83%), Query Frame = 3 
Query:   75 KSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
            + E+  D + F +   +   L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D  K+T+   N A+A+ IG+L I C +                P GC +  +    KDH   C + P
Sbjct:  123 EEEEEPDPLVFAEQPSVK--LCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNAKLTVVVNNIAVAEQIGELFIHCKYGCHPSSNGKPVTFEVDPRGCPFTIKLSARKDHEGSCDYRP 242
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:100216042])

HSP 1 Score: 69.3218 bits (168), Expect = 5.967e-13
Identity = 41/126 (32.54%), Postives = 59/126 (46.83%), Query Frame = 3 
Query:   75 KSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
            + E+  D + F +   +   L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D  K+T+   N A+A+ IG+L I C +                P GC +  +    KDH   C + P
Sbjct:  107 EEEEEPDPLVFAEQPSVK--LCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNAKLTVVVNNIAVAEQIGELFIHCKYGCHPSSNGKPVTFEVDPRGCPFTIKLSARKDHEGSCDYRP 226
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:100216042])

HSP 1 Score: 68.9366 bits (167), Expect = 7.109e-13
Identity = 41/126 (32.54%), Postives = 59/126 (46.83%), Query Frame = 3 
Query:   75 KSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
            + E+  D + F +   +   L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D  K+T+   N A+A+ IG+L I C +                P GC +  +    KDH   C + P
Sbjct:  101 EEEEEPDPLVFAEQPSVK--LCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNAKLTVVVNNIAVAEQIGELFIHCKYGCHPSSNGKPVTFEVDPRGCPFTIKLSARKDHEGSCDYRP 220
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:100216042])

HSP 1 Score: 68.9366 bits (167), Expect = 7.238e-13
Identity = 41/126 (32.54%), Postives = 59/126 (46.83%), Query Frame = 3 
Query:   75 KSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
            + E+  D + F +   +   L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D  K+T+   N A+A+ IG+L I C +                P GC +  +    KDH   C + P
Sbjct:   48 EEEEEPDPLVFAEQPSVK--LCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNAKLTVVVNNIAVAEQIGELFIHCKYGCHPSSNGKPVTFEVDPRGCPFTIKLSARKDHEGSCDYRP 167
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Traf7 (TNF receptor-associated factor 7 [Source:MGI Symbol;Acc:MGI:3042141])

HSP 1 Score: 69.707 bits (169), Expect = 1.145e-13
Identity = 48/148 (32.43%), Postives = 67/148 (45.27%), Query Frame = 3 
Query:   21 ATIKKNRKKQVSSDLF----QSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
             T K++R+   SS       + + +  E  ++ + P   S  L CQ+C  VF DP   +CGHTFCR C    L S K CP D  K+T+   N A+A+ IG+L I C                  P GC +  +    KDH   C + P
Sbjct:   50 GTYKQHRRTPSSSSTLAYSPRDEEDGMEPLVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCA---LKSEK-CPVDNAKLTVVVNNIAVAEQIGELFIHCRHGCHAAGTGKPGVFEVDPRGCPFTIKLSARKDHESSCDYRP 190
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Traf7 (TNF receptor-associated factor 7 [Source:MGI Symbol;Acc:MGI:3042141])

HSP 1 Score: 68.9366 bits (167), Expect = 5.555e-13
Identity = 48/148 (32.43%), Postives = 67/148 (45.27%), Query Frame = 3 
Query:   21 ATIKKNRKKQVSSDLF----QSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
             T K++R+   SS       + + +  E  ++ + P   S  L CQ+C  VF DP   +CGHTFCR C    L S K CP D  K+T+   N A+A+ IG+L I C                  P GC +  +    KDH   C + P
Sbjct:   51 GTYKQHRRTPSSSSTLAYSPRDEEDGMEPLVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCA---LKSEK-CPVDNAKLTVVVNNIAVAEQIGELFIHCRHGCHAAGTGKPGVFEVDPRGCPFTIKLSARKDHESSCDYRP 191
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Traf7 (TNF receptor-associated factor 7 [Source:MGI Symbol;Acc:MGI:3042141])

HSP 1 Score: 68.9366 bits (167), Expect = 5.555e-13
Identity = 48/148 (32.43%), Postives = 67/148 (45.27%), Query Frame = 3 
Query:   21 ATIKKNRKKQVSSDLF----QSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
             T K++R+   SS       + + +  E  ++ + P   S  L CQ+C  VF DP   +CGHTFCR C    L S K CP D  K+T+   N A+A+ IG+L I C                  P GC +  +    KDH   C + P
Sbjct:   51 GTYKQHRRTPSSSSTLAYSPRDEEDGMEPLVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCA---LKSEK-CPVDNAKLTVVVNNIAVAEQIGELFIHCRHGCHAAGTGKPGVFEVDPRGCPFTIKLSARKDHESSCDYRP 191
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf41 (ring finger protein 41 [Source:MGI Symbol;Acc:MGI:1914838])

HSP 1 Score: 66.2402 bits (160), Expect = 2.758e-12
Identity = 31/101 (30.69%), Postives = 51/101 (50.50%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            + E LIC IC  V  +P     C H FC  C+T W +  ++CP DR+ VT+         + +++  L+I+C    +GC  + R   +  H+  C+ NP +
Sbjct:   12 VDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf41 (ring finger protein 41 [Source:MGI Symbol;Acc:MGI:1914838])

HSP 1 Score: 66.2402 bits (160), Expect = 2.758e-12
Identity = 31/101 (30.69%), Postives = 51/101 (50.50%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            + E LIC IC  V  +P     C H FC  C+T W +  ++CP DR+ VT+         + +++  L+I+C    +GC  + R   +  H+  C+ NP +
Sbjct:   12 VDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7ZW16|RNF41_DANRE (E3 ubiquitin-protein ligase NRDP1 OS=Danio rerio OX=7955 GN=rnf41 PE=2 SV=1)

HSP 1 Score: 67.781 bits (164), Expect = 5.148e-12
Identity = 34/102 (33.33%), Postives = 51/102 (50.00%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            ++ E L+C IC  V  +P     C H FC  C+T W A  + CP DRT VTL         + +++  L+ISC    +GC    R   ++ H+  C+ NP +
Sbjct:   11 EVDEDLLCPICSGVLEEPVRAPHCEHAFCNACITQWFAQQQICPVDRTVVTLAHLRPVPRIMRNMLSKLQISCDNAGFGCTATLRLDQLQSHLKDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6ZMN7|PZRN4_HUMAN (PDZ domain-containing RING finger protein 4 OS=Homo sapiens OX=9606 GN=PDZRN4 PE=2 SV=3)

HSP 1 Score: 67.781 bits (164), Expect = 1.083e-11
Identity = 31/102 (30.39%), Postives = 47/102 (46.08%), Query Frame = 3 
Query:  135 LICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFA---------LADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            L C++C  V  +P C  CGH FC +C+  W    + CP       L C+  A         L  +I  L + C +R  GCG+  R + ++ H+  C F P +
Sbjct:   16 LECKLCGQVLEEPLCTPCGHVFCASCLLPWAVRRRRCP-------LQCQPLAPGELYRVLPLRSLIQKLRVQCDYRARGCGHSVRLHELEAHVEHCDFGPAR 110
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5R7T5|RNF41_PONAB (E3 ubiquitin-protein ligase NRDP1 OS=Pongo abelii OX=9601 GN=RNF41 PE=2 SV=1)

HSP 1 Score: 66.2402 bits (160), Expect = 1.719e-11
Identity = 31/101 (30.69%), Postives = 51/101 (50.50%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            + E LIC IC  V  +P     C H FC  C+T W +  ++CP DR+ VT+         + +++  L+I+C    +GC  + R   +  H+  C+ NP +
Sbjct:   12 VDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9H4P4|RNF41_HUMAN (E3 ubiquitin-protein ligase NRDP1 OS=Homo sapiens OX=9606 GN=RNF41 PE=1 SV=2)

HSP 1 Score: 66.2402 bits (160), Expect = 1.719e-11
Identity = 31/101 (30.69%), Postives = 51/101 (50.50%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            + E LIC IC  V  +P     C H FC  C+T W +  ++CP DR+ VT+         + +++  L+I+C    +GC  + R   +  H+  C+ NP +
Sbjct:   12 VDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8BH75|RNF41_MOUSE (E3 ubiquitin-protein ligase NRDP1 OS=Mus musculus OX=10090 GN=Rnf41 PE=1 SV=1)

HSP 1 Score: 66.2402 bits (160), Expect = 1.929e-11
Identity = 31/101 (30.69%), Postives = 51/101 (50.50%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            + E LIC IC  V  +P     C H FC  C+T W +  ++CP DR+ VT+         + +++  L+I+C    +GC  + R   +  H+  C+ NP +
Sbjct:   12 VDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A2G8LB09 (RING-type domain-containing protein OS=Stichopus japonicus OX=307972 GN=BSL78_05687 PE=4 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 2.564e-29
Identity = 65/191 (34.03%), Postives = 99/191 (51.83%), Query Frame = 3 
Query:   33 KNRKKQVSSDLFQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTL--CCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTPPAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLY 599
            + R K+   D   +K  + E+  YF +P  +S HL C +CQ+VF DP    CGH+FCR C+  WL  +K+CP DR  V +     +F +A+IIGD  ++CS+R  GC +IG+  ++K H   C FNP  +   +     H      P++    S S     ++S ++      D   LP   +PSL  RL+
Sbjct:    6 RRRTKRSRDDSTSTKVIEDEEDRYFLNPDSVSRHLFCSVCQEVFKDPQRAPCGHSFCRMCILRWLKQSKTCPEDRRPVRVQDLHTDFIVANIIGDQMVACSFRGKGCEFIGKLELLKCHTKNCDFNPANLPEFLANDDNH---QIQPSRDKSFSES-----VLSPINAPTCSSDPDKLPTPAKPSLKMRLF 188
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: C3YTN8 (RING-type domain-containing protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_118249 PE=4 SV=1)

HSP 1 Score: 117.472 bits (293), Expect = 9.449e-29
Identity = 68/208 (32.69%), Postives = 111/208 (53.37%), Query Frame = 3 
Query:   45 KQVSSDLFQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTL--CCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTPPAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYMINETKDTLVRFLSEKISFPK 662
            K+   D   + S + E++ YF +P+ +SEHL C ICQDVF +P    CGH++C+ C+  WL ++K+CP DR  V       +F LA+IIGD  ++C +R  GC +IG+  ++  H   C FNP  +   + E+        P +     +++ ++D   S L      DD   LP   +PSL  RL+    ++  L++ + +K + PK
Sbjct:    4 KRKRGDEGFADSNEGEEERYFLNPESVSEHLYCSICQDVFKEPQRAPCGHSYCKQCIMAWLRTSKTCPEDRRPVREKDLHYDFILANIIGDHMVACPFRKLGCEFIGKLELLTSHRKSCCFNPANLPEFLLEE--------PQSSTAAAATASSVDTSSSFL---CTSDDENKLPSPPKPSLKMRLFKNGASQRDLLKNMFDKENRPK 200
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A2G8JHQ6 (RING-type domain-containing protein OS=Stichopus japonicus OX=307972 GN=BSL78_27924 PE=4 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 1.128e-28
Identity = 62/172 (36.05%), Postives = 91/172 (52.91%), Query Frame = 3 
Query:   90 EDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTL--CCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTPPAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLY 599
            E+  YF +P  +S HL C +CQ+VF DP    CGH+FCR C+  WL  +K+CP DR  V +     +F +A+IIGD  ++CS+R  GC +IG+  ++K H   C FNP  +   +     H      P+K    S S     ++S ++      D   LP   +PSL  RL+
Sbjct:   25 EEDRYFLNPDSVSRHLFCSVCQEVFKDPQRAPCGHSFCRMCILRWLKQSKTCPEDRRPVRVQDLHTDFIVANIIGDQMVACSFRGKGCEFIGKLELLKCHTKNCDFNPANLPEFLANDDNH---QIQPSKDKSFSES-----VLSPINAPTCSSDPDKLPTPAKPSLKMRLF 188
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A0R3SBF4 (RING-type domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS1800 PE=4 SV=1)

HSP 1 Score: 117.472 bits (293), Expect = 2.858e-28
Identity = 72/229 (31.44%), Postives = 110/229 (48.03%), Query Frame = 3 
Query:   36 NRKKQVSSDLFQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTL--CCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTPPAKKTKQSSSGA-------------------LDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYM-INE-TKDTLVRFLSEKIS 653
            +R++  +     S S   +++  F  P KIS HL C IC +VF +P+   CGH++C  C+T W+ + K CP DR  ++L     +F L  IIGD  ++C WR  GC Y+G    +  H   C  NP+ +  V++ + +         +  KQ +SG                    L E +  LDD+I +D+   LP    PSL  RL+   NE ++D L  FL   +S
Sbjct:   14 SRREAGNCQDHSSNSSTEQEERRFARPDKISPHLFCVICSEVFKNPYRAPCGHSYCYMCITKWMETAKICPVDRKCISLKQMHHDFILESIIGDYTVACPWRASGCSYVGPLCQLDSHKKVCVMNPDLLPEVLRAREK---------ESIKQRNSGGSMPSTSSSFPPPVSISSHDLSESLDGLDDTINDDEEGHLPPAPPPSLVMRLFQNANESSRDLLCNFLGGSLS 233
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A210PF94 (E3 ubiquitin-protein ligase PDZRN3 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT05403 PE=4 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 2.065e-27
Identity = 58/182 (31.87%), Postives = 95/182 (52.20%), Query Frame = 3 
Query:   90 EDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTL--CCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTPPAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYMINETKDTLV 629
            E++ YF +P  +S HL C ICQDVF+DP    CGH+FC+ C+  WL ++K+CP DR  + +     +F L +IIGD  ++C +R  GC ++G+   +  H  +C FNP  +   +++        + P + T+   SG             +  DL  +P   +PSL  RL+   + +  L+
Sbjct:   18 EEERYFLNPDSVSTHLYCSICQDVFSDPQRAPCGHSFCKKCILPWLKNSKTCPEDRKTLHIGHLHHDFILENIIGDQMVACPFRRLGCEFVGQLQSLNSHKKRCDFNPENLPEFIKK--------STPVENTRGQHSG-------------ITTDLEVVPSPGKPSLMMRLFRAGDDQKKLL 178
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:103038327])

HSP 1 Score: 71.633 bits (174), Expect = 5.247e-14
Identity = 41/129 (31.78%), Postives = 61/129 (47.29%), Query Frame = 3 
Query:   66 FQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
               + E  E +++ + P   S  L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D +K+T+   N A+A+ IG+L + C +                P GC +  +    KDH   C + P
Sbjct:  127 LHEEEEDTEPQVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNSKLTVVVNNIAVAEQIGELFVHCKYGCRPSASGKPGAFEVDPLGCPFTIKLSTRKDHEGSCDYRP 248
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:103038327])

HSP 1 Score: 71.633 bits (174), Expect = 6.308e-14
Identity = 41/129 (31.78%), Postives = 61/129 (47.29%), Query Frame = 3 
Query:   66 FQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
               + E  E +++ + P   S  L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D +K+T+   N A+A+ IG+L + C +                P GC +  +    KDH   C + P
Sbjct:   33 LHEEEEDTEPQVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNSKLTVVVNNIAVAEQIGELFVHCKYGCRPSASGKPGAFEVDPLGCPFTIKLSTRKDHEGSCDYRP 154
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:103038327])

HSP 1 Score: 71.633 bits (174), Expect = 6.352e-14
Identity = 41/129 (31.78%), Postives = 61/129 (47.29%), Query Frame = 3 
Query:   66 FQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
               + E  E +++ + P   S  L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D +K+T+   N A+A+ IG+L + C +                P GC +  +    KDH   C + P
Sbjct:   77 LHEEEEDTEPQVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNSKLTVVVNNIAVAEQIGELFVHCKYGCRPSASGKPGAFEVDPLGCPFTIKLSTRKDHEGSCDYRP 198
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:103038327])

HSP 1 Score: 70.8626 bits (172), Expect = 1.095e-13
Identity = 40/124 (32.26%), Postives = 60/124 (48.39%), Query Frame = 3 
Query:   81 EKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWR---------------PYGCGYIGRYYIVKDHIVKCKFNP 407
            +  E +++ + P   S  L CQ+C  VF DP   +CGHTFCR C  T    ++ CP D +K+T+   N A+A+ IG+L + C +                P GC +  +    KDH   C + P
Sbjct:   50 DGMEPQVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCALT----SEKCPVDNSKLTVVVNNIAVAEQIGELFVHCKYGCRPSASGKPGAFEVDPLGCPFTIKLSTRKDHEGSCDYRP 166
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: rnf41 (ring finger protein 41 [Source:NCBI gene;Acc:103035049])

HSP 1 Score: 68.1662 bits (165), Expect = 1.145e-13
Identity = 34/102 (33.33%), Postives = 51/102 (50.00%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            ++ E L+C IC  V  +P     C H FC  C+T W A  + CP DRT VTL         + +++  L+ISC    +GC    R   ++ H+  C+ NP +
Sbjct:   11 EVDEDLLCPICSGVLEEPVQAPHCEHAFCNACITQWFAQQQICPVDRTVVTLAHLRPVPRIMRNMLSKLQISCDNAGFGCTATLRLDQLQSHLKDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: rnf41l (ring finger protein 41, like [Source:ZFIN;Acc:ZDB-GENE-030131-9441])

HSP 1 Score: 55.4546 bits (132), Expect = 2.891e-10
Identity = 28/100 (28.00%), Postives = 46/100 (46.00%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKV---TLCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPN 410
            ++ + L+C +C+DV  DP    C H FC  C+  WL  N +CP DR  +    L      + + +  L + C+ R  GC  +     +  H  +C + P 
Sbjct:   11 RVKDGLLCCVCRDVLEDPLQAPCEHAFCSACIHGWLVHNHTCPEDRQPLDASELRPLFRYMRNDLNALRLHCTHRARGCEGVCALETIAIHEQQCPYTPT 110
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: rnf41 (ring finger protein 41 [Source:NCBI gene;Acc:406837])

HSP 1 Score: 50.0618 bits (118), Expect = 1.520e-7
Identity = 33/102 (32.35%), Postives = 46/102 (45.10%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDPWCLSCGHT-FCRTCVTT-WLASNKSCPTDRTKVT---LCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            + E LIC IC  V  +P  L   H   C  CV T WL   ++CP DR+ VT   L      + +++  L I C   P GC  + R  ++  H V+      K
Sbjct:   12 VDEELICPICSGVLEEP--LQAPHMDHCTACVITQWLLRQQTCPVDRSVVTPAHLKPVPRIMRNMLSKLTIRCENAPSGCTAMLRLDLLASHAVRSSRAAGK 111
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008283.1 (pep scaffold:Pmarinus_7.0:GL492550:1249:4726:-1 gene:ENSPMAG00000007497.1 transcript:ENSPMAT00000008283.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.521 bits (114), Expect = 6.025e-7
Identity = 27/82 (32.93%), Postives = 39/82 (47.56%), Query Frame = 3 
Query:   69 QSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDL 314
            Q K+EK +    F++   +   L C IC ++F     LSC HTFCR C+  WL   + CP  R   T    +  L + I  +
Sbjct:  325 QEKTEKKQVICSFEN--VMENELQCIICSELFIQATTLSCAHTFCRNCIEEWLKQKELCPICRASPTSSTPSLVLDNCIARM 404
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008284.1 (pep scaffold:Pmarinus_7.0:GL492550:1249:4726:-1 gene:ENSPMAG00000007497.1 transcript:ENSPMAT00000008284.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.521 bits (114), Expect = 6.186e-7
Identity = 27/82 (32.93%), Postives = 39/82 (47.56%), Query Frame = 3 
Query:   69 QSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDL 314
            Q K+EK +    F++   +   L C IC ++F     LSC HTFCR C+  WL   + CP  R   T    +  L + I  +
Sbjct:  324 QEKTEKKQVICSFEN--VMENELQCIICSELFIQATTLSCAHTFCRNCIEEWLKQKELCPICRASPTSSTPSLVLDNCIARM 403
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001651.1 (pep scaffold:Pmarinus_7.0:GL478037:21275:40632:1 gene:ENSPMAG00000001486.1 transcript:ENSPMAT00000001651.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 47.3654 bits (111), Expect = 1.342e-6
Identity = 26/77 (33.77%), Postives = 38/77 (49.35%), Query Frame = 3 
Query:  117 KKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTT-WLASNK-----SCPTDRTKVT---LCCKNFALADIIGDLEI 320
            K++ E L C +C + F +P  L CGH FC+ C+   W A        SCP  R +     L  KN  LA+++  L +
Sbjct:    6 KQLGEELTCVVCMEEFAEPVTLGCGHNFCQGCIERCWEAEEGAGAPPSCPQCRRRFAARPLLQKNTVLANVVKQLSL 82
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Yeast
Match: PSH1 (E3 ubiquitin ligase targeting centromere-binding protein Cse4p; mediates polyubiquitination and degradation of histone H3 variant Cse4p, preventing its mislocalization to euchromatin independent of Slx5p; ubiquitination of Cse4p may be antagonized by Scm3p [Source:SGD;Acc:S000005415])

HSP 1 Score: 48.521 bits (114), Expect = 3.107e-7
Identity = 23/54 (42.59%), Postives = 29/54 (53.70%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNK----SCPTDRTKVT 269
            KI E L+C IC D    P    CGH +C  C+ TW ASN     +CP  R+ +T
Sbjct:   23 KIIESLVCSICHDYMFVPMMTPCGHNYCYGCLNTWFASNTQKELACPQCRSDIT 76
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO48004 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKK9])

HSP 1 Score: 65.0846 bits (157), Expect = 3.205e-12
Identity = 42/111 (37.84%), Postives = 56/111 (50.45%), Query Frame = 3 
Query:   81 EKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            E+ E+ I F D  K S  L C +C+ VF DP   SCGHTFC+ C+       + CP D  K+++   N A+A+ IG+L I C    YGC        V +H V     P K
Sbjct:  115 EEEEEIILFVD--KPSPKLFCPLCRRVFKDPVITSCGHTFCQACIMA--RGVEKCPLDDNKLSIVVANLAVAEQIGELYIHC---KYGCRIRANGGGVVEHEVDSSGCPMK 218
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO49523 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGH1])

HSP 1 Score: 63.929 bits (154), Expect = 4.568e-12
Identity = 34/102 (33.33%), Postives = 50/102 (49.02%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDPW-CLSCGHTFCRTCVTTWLASNKSCPTDRTKVT-LCCKNFA--LADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            ++ E L+C IC  V  DP     C H FC  C+  WL    +CP DR  +T L  K     L +++  L ISC    +GC  + R   ++ H+ +C  NP +
Sbjct:   11 EVDEELVCSICGGVLEDPLQAPVCEHAFCAGCIHEWLNHQNNCPIDRRTLTPLQLKQVPRILKNLLSKLVISCDNVTFGCEVMVRLDGLQSHLAQCDHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO34728 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNG3])

HSP 1 Score: 61.2326 bits (147), Expect = 7.384e-12
Identity = 34/100 (34.00%), Postives = 49/100 (49.00%), Query Frame = 3 
Query:  123 ISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFA-----LADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNP 407
            +S  L+C IC  V  DP    C H FC  C++ WL +N +CPT R++V    KN       + +II  L+I C ++  GC  I     ++ H   C   P
Sbjct:   11 VSPELVCCICTGVLEDPVESPCRHVFCSECISKWLQNNSNCPTCRSQVRA--KNLKPVLPLVRNIISKLKIHCDFKTQGCKAIVSLESLRRHATICVMAP 108
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO48236 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF3])

HSP 1 Score: 58.5362 bits (140), Expect = 3.612e-10
Identity = 35/108 (32.41%), Postives = 48/108 (44.44%), Query Frame = 3 
Query:  105 FKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALAD---------IIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKF 401
            F DP  + +   C IC  V  DP   +CGH FC  C+  W+A N +CP       L C+  A+ D         +I  L I C     GC  I R   ++ H  KC++
Sbjct:    8 FLDP--VEDDFKCGICFGVLEDPLVTTCGHVFCSQCLVHWIAENGTCP-------LTCEQLAIDDLKKIPPLTRLISLLNIRCCNFQRGCPAILRIESIQTHQRKCQY 106
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO46837 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP22])

HSP 1 Score: 51.9878 bits (123), Expect = 1.152e-8
Identity = 30/99 (30.30%), Postives = 49/99 (49.49%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLA--SNKSCPTDRTKVTL--CCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFN 404
            KI ++L+C IC  V  +     CGH+FC +C+ TWL+    +SCP+ R+ V         A+  ++  L + C     GC  + R   +K H+  C + 
Sbjct:   11 KIDQNLLCNICVGVLENAITTICGHSFCESCLETWLSRPEVQSCPSCRSHVLSLDLIPVHAIRGLVDGLLVHCENADNGCDIVTRMDNMKSHLESCPYG 109
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: rnf41 (ring finger protein 41 [Source:NCBI gene;Acc:101155196])

HSP 1 Score: 68.1662 bits (165), Expect = 4.260e-13
Identity = 34/102 (33.33%), Postives = 51/102 (50.00%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDP-WCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN---FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            ++ E L+C IC  V  +P     C H FC  C+T W A  + CP DRT VTL         + +++  L+I+C    YGC    R   ++ H+  C+ NP +
Sbjct:   11 EVDEDLLCPICSGVLEEPVQAPHCEHAFCNACITQWFAQQQICPVDRTVVTLAHLRPVPRIMRNMLSKLQINCDNASYGCTATLRLDQLQSHLKDCEHNPKR 112
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:101168715])

HSP 1 Score: 66.6254 bits (161), Expect = 2.646e-12
Identity = 38/94 (40.43%), Postives = 52/94 (55.32%), Query Frame = 3 
Query:   66 FQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWRPYGC 347
               + E  E +++ + P   S  L CQ+C  VF DP   +CGHTFCR C    L S+K CP D  K+T+   N A+A+ IG+L + C    YGC
Sbjct:   80 LHEEEEDAEPQVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCA---LTSDK-CPVDAAKLTVVVNNIAVAEQIGELFVHCK---YGC 163
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:101168715])

HSP 1 Score: 66.6254 bits (161), Expect = 2.647e-12
Identity = 38/94 (40.43%), Postives = 52/94 (55.32%), Query Frame = 3 
Query:   66 FQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWRPYGC 347
               + E  E +++ + P   S  L CQ+C  VF DP   +CGHTFCR C    L S+K CP D  K+T+   N A+A+ IG+L + C    YGC
Sbjct:   80 LHEEEEDAEPQVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCA---LTSDK-CPVDAAKLTVVVNNIAVAEQIGELFVHCK---YGC 163
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: traf7 (TNF receptor associated factor 7 [Source:NCBI gene;Acc:101168715])

HSP 1 Score: 66.6254 bits (161), Expect = 3.194e-12
Identity = 38/94 (40.43%), Postives = 52/94 (55.32%), Query Frame = 3 
Query:   66 FQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWRPYGC 347
               + E  E +++ + P   S  L CQ+C  VF DP   +CGHTFCR C    L S+K CP D  K+T+   N A+A+ IG+L + C    YGC
Sbjct:   78 LHEEEEDAEPQVFAEQP---SVKLCCQLCCSVFKDPVITTCGHTFCRRCA---LTSDK-CPVDAAKLTVVVNNIAVAEQIGELFVHCK---YGC 161
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: pdzrn3b (PDZ domain containing ring finger 3 [Source:NCBI gene;Acc:101166295])

HSP 1 Score: 61.2326 bits (147), Expect = 1.910e-10
Identity = 30/93 (32.26%), Postives = 42/93 (45.16%), Query Frame = 3 
Query:  141 CQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKN--FALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNK 413
            C +C  V  +P    CGH FC  CV  W+    SCP    +V+    N    L ++I  LEI C     GC  + +   + +H   C F+P K
Sbjct:   18 CNLCNKVLEEPLTTPCGHVFCSGCVLPWVVQQSSCPVKCQRVSARELNHVLPLKNLILKLEIKCDNHARGCDAVVKLQHLAEHAETCDFSPAK 110
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000075014.1 (SMESG000075014.1)

HSP 1 Score: 431.795 bits (1109), Expect = 9.321e-156
Identity = 210/216 (97.22%), Postives = 212/216 (98.15%), Query Frame = 3 
Query:   18 MATIKKNRKKQVSSDLFQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTP--PAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYMINETKDTLVRFLSEKISFP 659
            MATIKKNRKKQVSSDLFQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALA+IIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTP  PAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYMINETKDTLVRFLS+K  FP
Sbjct:    1 MATIKKNRKKQVSSDLFQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALANIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTPPTPAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYMINETKDTLVRFLSDKPVFP 216
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000075024.1 (SMESG000075024.1)

HSP 1 Score: 410.223 bits (1053), Expect = 2.431e-147
Identity = 199/217 (91.71%), Postives = 203/217 (93.55%), Query Frame = 3 
Query:   18 MATIKKNRKKQVSSDLFQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTP--PAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYMINETKDTLVRFLSEKISFPK 662
            M T KKN KK+VSSDLFQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTC+T W+ SN SCP DRTKVTLCCKNF LA+IIGDLEISCSWRPYGC YIGRYYIVKDH VKCKFNPNKMDP MQEKMR INVDTP  PAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYMINETKDTLVRFLSEKISFPK
Sbjct:    1 MVTKKKNTKKRVSSDLFQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCITQWIVSNNSCPADRTKVTLCCKNFTLANIIGDLEISCSWRPYGCNYIGRYYIVKDHNVKCKFNPNKMDPAMQEKMRLINVDTPPTPAKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYMINETKDTLVRFLSEKISFPK 217
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000068479.1 (SMESG000068479.1)

HSP 1 Score: 69.3218 bits (168), Expect = 1.355e-13
Identity = 37/107 (34.58%), Postives = 61/107 (57.01%), Query Frame = 3 
Query:  120 KISEHLICQICQDVFNDPWCLS-CGHTFCRTCVTTWLASNKSCPTDR---TKVTLCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVM 428
            ++ E L C IC++V ++P   S C HTFC +C+T WL  + SCP DR   TK  L      + +++  L + C ++  GC  I +   +  H+ +C++NP+K  P+M
Sbjct:   11 EVDEELFCSICKNVLDNPVQASKCEHTFCSSCITEWLKFDSSCPIDRKILTKYELKPVPRIIKNLLNKLTLFCDYKIDGCPKILKLEYLMSHVKECEYNPSK--PIM 115
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000018435.1 (SMESG000018435.1)

HSP 1 Score: 51.2174 bits (121), Expect = 2.388e-7
Identity = 34/114 (29.82%), Postives = 57/114 (50.00%), Query Frame = 3 
Query:   66 FQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLASNKS-CPTDRTKV-TLCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKF 401
            F  ++E F   I  + P+      +C  C ++  DP    CG  FC +C+    AS ++ CP  +T++     K+ A+   I +LEI C     GC +IG++  + DH+  CK+
Sbjct:   14 FDKRTEYFIKNIRLECPR-----FVCSKCHEILIDPSQTQCGCRFCYSCINKHFASCENICPNCQTEIPNEIIKDRAIDREISNLEIRCLLN--GCDHIGQFKYLDDHLRMCKW 120
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000018409.1 (SMESG000018409.1)

HSP 1 Score: 51.2174 bits (121), Expect = 2.637e-7
Identity = 37/135 (27.41%), Postives = 65/135 (48.15%), Query Frame = 3 
Query:   66 FQSKSEKFEDKIYFKDPKKISEHLICQICQDVFNDPWCLSCGHTFCRTCVTTWLAS-NKSCPTDRTKV-TLCCKNFALADIIGDLEISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQ---EKMRHINV 455
             ++++E F   I  + P+      +C  C ++  DP    CG  FC +C+    AS    CP  +T++     K+ A+   I +LEI C     GC +IG++  + DH+  CK+     D   Q   ++M+ I++
Sbjct:   12 LETRTEYFIKNIRLECPR-----FVCSKCHEILIDPSQTQCGCRFCYSCINKHFASCGNICPNCQTEIPNEIIKDRAIDREISNLEIRCLLN--GCDHIGQFKYLDDHLKMCKWRLENCDKCHQTYPKQMKEIHL 139
The following BLAST results are available for this feature:
BLAST of RING-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RNF419.723e-1330.69ring finger protein 41 [Source:HGNC Symbol;Acc:HGN... [more]
RNF411.211e-1230.69ring finger protein 41 [Source:HGNC Symbol;Acc:HGN... [more]
PDZRN42.255e-1230.39PDZ domain containing ring finger 4 [Source:HGNC S... [more]
RNF413.580e-1230.69ring finger protein 41 [Source:HGNC Symbol;Acc:HGN... [more]
RNF413.580e-1230.69ring finger protein 41 [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of RING-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
elgi2.133e-1333.33gene:FBgn0283649 transcript:FBtr0075510[more]
elgi2.133e-1333.33gene:FBgn0283649 transcript:FBtr0333573[more]
CG90143.114e-1227.44gene:FBgn0028847 transcript:FBtr0343664[more]
CG90143.114e-1227.44gene:FBgn0028847 transcript:FBtr0080579[more]
CG136058.530e-950.00gene:FBgn0039150 transcript:FBtr0300705[more]
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BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf73.634e-1534.88TNF receptor-associated factor 7 [Source:ZFIN;Acc:... [more]
traf73.634e-1534.88TNF receptor-associated factor 7 [Source:ZFIN;Acc:... [more]
traf73.897e-1534.88TNF receptor-associated factor 7 [Source:ZFIN;Acc:... [more]
rnf415.516e-1333.33ring finger protein 41 [Source:NCBI gene;Acc:40683... [more]
rnf415.516e-1333.33ring finger protein 41 [Source:NCBI gene;Acc:40683... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf75.139e-1332.54TNF receptor associated factor 7 [Source:NCBI gene... [more]
traf75.323e-1332.54TNF receptor associated factor 7 [Source:NCBI gene... [more]
traf75.967e-1332.54TNF receptor associated factor 7 [Source:NCBI gene... [more]
traf77.109e-1332.54TNF receptor associated factor 7 [Source:NCBI gene... [more]
traf77.238e-1332.54TNF receptor associated factor 7 [Source:NCBI gene... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Traf71.145e-1332.43TNF receptor-associated factor 7 [Source:MGI Symbo... [more]
Traf75.555e-1332.43TNF receptor-associated factor 7 [Source:MGI Symbo... [more]
Traf75.555e-1332.43TNF receptor-associated factor 7 [Source:MGI Symbo... [more]
Rnf412.758e-1230.69ring finger protein 41 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf412.758e-1230.69ring finger protein 41 [Source:MGI Symbol;Acc:MGI:... [more]
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BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7ZW16|RNF41_DANRE5.148e-1233.33E3 ubiquitin-protein ligase NRDP1 OS=Danio rerio O... [more]
sp|Q6ZMN7|PZRN4_HUMAN1.083e-1130.39PDZ domain-containing RING finger protein 4 OS=Hom... [more]
sp|Q5R7T5|RNF41_PONAB1.719e-1130.69E3 ubiquitin-protein ligase NRDP1 OS=Pongo abelii ... [more]
sp|Q9H4P4|RNF41_HUMAN1.719e-1130.69E3 ubiquitin-protein ligase NRDP1 OS=Homo sapiens ... [more]
sp|Q8BH75|RNF41_MOUSE1.929e-1130.69E3 ubiquitin-protein ligase NRDP1 OS=Mus musculus ... [more]
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BLAST of RING-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2G8LB092.564e-2934.03RING-type domain-containing protein OS=Stichopus j... [more]
C3YTN89.449e-2932.69RING-type domain-containing protein OS=Branchiosto... [more]
A0A2G8JHQ61.128e-2836.05RING-type domain-containing protein OS=Stichopus j... [more]
A0A0R3SBF42.858e-2831.44RING-type domain-containing protein OS=Hymenolepis... [more]
A0A210PF942.065e-2731.87E3 ubiquitin-protein ligase PDZRN3 OS=Mizuhopecten... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf75.247e-1431.78TNF receptor associated factor 7 [Source:NCBI gene... [more]
traf76.308e-1431.78TNF receptor associated factor 7 [Source:NCBI gene... [more]
traf76.352e-1431.78TNF receptor associated factor 7 [Source:NCBI gene... [more]
traf71.095e-1332.26TNF receptor associated factor 7 [Source:NCBI gene... [more]
rnf411.145e-1333.33ring finger protein 41 [Source:NCBI gene;Acc:10303... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf41l2.891e-1028.00ring finger protein 41, like [Source:ZFIN;Acc:ZDB-... [more]
rnf411.520e-732.35ring finger protein 41 [Source:NCBI gene;Acc:40683... [more]
ENSPMAT00000008283.16.025e-732.93pep scaffold:Pmarinus_7.0:GL492550:1249:4726:-1 ge... [more]
ENSPMAT00000008284.16.186e-732.93pep scaffold:Pmarinus_7.0:GL492550:1249:4726:-1 ge... [more]
ENSPMAT00000001651.11.342e-633.77pep scaffold:Pmarinus_7.0:GL478037:21275:40632:1 g... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
PSH13.107e-742.59E3 ubiquitin ligase targeting centromere-binding p... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO480043.205e-1237.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO495234.568e-1233.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO347287.384e-1234.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO482363.612e-1032.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO468371.152e-830.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf414.260e-1333.33ring finger protein 41 [Source:NCBI gene;Acc:10115... [more]
traf72.646e-1240.43TNF receptor associated factor 7 [Source:NCBI gene... [more]
traf72.647e-1240.43TNF receptor associated factor 7 [Source:NCBI gene... [more]
traf73.194e-1240.43TNF receptor associated factor 7 [Source:NCBI gene... [more]
pdzrn3b1.910e-1032.26PDZ domain containing ring finger 3 [Source:NCBI g... [more]
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BLAST of RING-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000075014.19.321e-15697.22SMESG000075014.1[more]
SMESG000075024.12.431e-14791.71SMESG000075024.1[more]
SMESG000068479.11.355e-1334.58SMESG000068479.1[more]
SMESG000018435.12.388e-729.82SMESG000018435.1[more]
SMESG000018409.12.637e-727.41SMESG000018409.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007147 ID=SMED30007147|Name=RING-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=742bp
TATAATATATTTTATAGATGGCAACTATAAAGAAGAATAGAAAAAAACAA
GTATCGTCAGACTTATTTCAGAGTAAAAGTGAGAAATTCGAAGATAAAAT
ATACTTCAAAGATCCCAAAAAAATCAGCGAACATCTAATATGTCAAATTT
GTCAAGATGTTTTTAATGATCCATGGTGTTTATCTTGTGGCCATACATTT
TGTAGAACGTGTGTTACAACCTGGCTAGCCTCAAACAAATCATGTCCTAC
CGATAGGACGAAGGTTACTCTTTGTTGCAAAAATTTTGCTCTAGCTGACA
TTATCGGTGATCTTGAAATATCGTGTTCTTGGCGACCATATGGCTGTGGC
TACATTGGTCGTTATTATATTGTAAAAGATCATATTGTGAAATGTAAATT
TAACCCTAACAAAATGGATCCAGTAATGCAAGAGAAAATGAGGCATATTA
ATGTCGATACTCCACCGGCAAAGAAAACAAAACAATCCAGTAGTGGTGCG
TTAGATGAATTAATGTCGCAATTAGATGATTCAATAGTAGAAGACGATCT
TACGTCTCTCCCCCAACTGGAGGAGCCATCTCTTGCCGCTAGACTTTATA
TGATAAATGAAACTAAAGATACACTTGTCCGATTTCTTAGTGAAAAAATC
TCTTTTCCCAAATAATATTTACTAATATATTTGTATTTATCTTGTCGCAA
TGATTTTTTTTATTATATTAATCTGTTTTGATTTGTTGACAA
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protein sequence of SMED30007147-orf-1

>SMED30007147-orf-1 ID=SMED30007147-orf-1|Name=SMED30007147-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=216bp
MATIKKNRKKQVSSDLFQSKSEKFEDKIYFKDPKKISEHLICQICQDVFN
DPWCLSCGHTFCRTCVTTWLASNKSCPTDRTKVTLCCKNFALADIIGDLE
ISCSWRPYGCGYIGRYYIVKDHIVKCKFNPNKMDPVMQEKMRHINVDTPP
AKKTKQSSSGALDELMSQLDDSIVEDDLTSLPQLEEPSLAARLYMINETK
DTLVRFLSEKISFPK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR003613Ubox_domain
IPR001841Znf_RING
IPR013083Znf_RING/FYVE/PHD
IPR017907Znf_RING_CS
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0008270zinc ion binding
GO:0004842ubiquitin-protein transferase activity
Vocabulary: biological process
TermDefinition
GO:0016567protein ubiquitination
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001841Zinc finger, RING-typeSMARTSM00184ring_2coord: 42..79
e-value: 5.1E-5
score: 32.7
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 42..80
score: 12.917
IPR003613U box domainSMARTSM00504Ubox_2coord: 39..99
e-value: 0.0045
score: 17.6
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 7..136
e-value: 7.5E-22
score: 79.7
NoneNo IPR availablePFAMPF13923zf-C3HC4_2coord: 42..78
e-value: 1.3E-10
score: 41.0
NoneNo IPR availablePANTHERPTHR15315:SF76coord: 25..148
NoneNo IPR availablePANTHERPTHR15315RING FINGER PROTEIN 41, 151coord: 25..148
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 34..109
IPR017907Zinc finger, RING-type, conserved sitePROSITEPS00518ZF_RING_1coord: 57..66