Kunitz-type serine protease inhibitor 6

Overview


Name	Kunitz-type serine protease inhibitor 6
Smed ID	SMED30007141
Length (bp)	336

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Kunitz-type serine protease inhibitor 6 (SMED30007141) t-SNE clustered cells

Violin plots show distribution of expression levels for Kunitz-type serine protease inhibitor 6 (SMED30007141) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Kunitz-type serine protease inhibitor 6 (SMED30007141) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Kunitz-type serine protease inhibitor 6 (SMED30007141) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30007141

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
prepharyngeal region	SMED30007141	SMESG000013915.1 SMESG000013910.1	SmedASXL_015573	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pigment cell	SMED30007141	SMESG000013915.1 SMESG000013910.1	SmedASXL_015573	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
gut	SMED30007141	SMESG000013915.1 SMESG000013910.1	dd_Smed_v4_41_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
tail region	SMED30007141	SMESG000013915.1 SMESG000013910.1	dd_Smed_v6_41_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
goblet cell	SMED30007141	SMESG000013915.1 SMESG000013910.1	dd_Smed_v6_41_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 63.5438 bits (153), Expect = 8.754e-13
Identity = 29/53 (54.72%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C L ++ G+CRGY  RYF+N +T +CE+F YGGC GN NNF T  EC+  CE 
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177

HSP 2 Score: 51.6026 bits (122), Expect = 2.035e-8
Identity = 23/51 (45.10%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C+   + G C+    R+FFN  T +CE+FIYGGC+GN+N F +  EC+  C
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104

[Close]

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C L ++ G+CRGY  RYF+N +T +CE+F YGGC GN NNF T  EC+  CE 
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177

HSP 2 Score: 51.6026 bits (122), Expect = 2.035e-8
Identity = 23/51 (45.10%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C+   + G C+    R+FFN  T +CE+FIYGGC+GN+N F +  EC+  C
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 62.7734 bits (151), Expect = 1.035e-12
Identity = 29/53 (54.72%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C L ++ G+CRGY  RYF+N +T +CE+F YGGC GN NNF T  EC+  CE 
Sbjct:  112 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 164

HSP 2 Score: 51.2174 bits (121), Expect = 2.131e-8
Identity = 23/51 (45.10%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C+   + G C+    R+FFN  T +CE+FIYGGC+GN+N F +  EC+  C
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 62.7734 bits (151), Expect = 2.498e-12
Identity = 29/53 (54.72%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C L ++ G+CRGY  RYF+N +T +CE+F YGGC GN NNF T  EC+  CE 
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177

HSP 2 Score: 51.2174 bits (121), Expect = 3.915e-8
Identity = 23/51 (45.10%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C+   + G C+    R+FFN  T +CE+FIYGGC+GN+N F +  EC+  C
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104

HSP 3 Score: 48.521 bits (114), Expect = 2.766e-7
Identity = 23/53 (43.40%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C  P + GLCR    R+++N   GKC  F Y GC GN+NNF +  EC   C++
Sbjct:  217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 62.7734 bits (151), Expect = 2.498e-12
Identity = 29/53 (54.72%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C L ++ G+CRGY  RYF+N +T +CE+F YGGC GN NNF T  EC+  CE 
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177

HSP 2 Score: 51.2174 bits (121), Expect = 3.915e-8
Identity = 23/51 (45.10%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C+   + G C+    R+FFN  T +CE+FIYGGC+GN+N F +  EC+  C
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104

HSP 3 Score: 48.521 bits (114), Expect = 2.766e-7
Identity = 23/53 (43.40%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C  P + GLCR    R+++N   GKC  F Y GC GN+NNF +  EC   C++
Sbjct:  217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 64.6994 bits (156), Expect = 3.286e-13
Identity = 25/51 (49.02%), Postives = 36/51 (70.59%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C++P + G+C  Y PR+FFN +TG+CE+F YG C GN+NNF+    C  +C
Sbjct: 2177 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2227

HSP 2 Score: 56.9954 bits (136), Expect = 1.468e-10
Identity = 26/51 (50.98%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C  P++ G CRG F R+FF++E   C+ F Y GCQGN NNF +  EC A C
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 787

HSP 3 Score: 54.299 bits (129), Expect = 1.232e-9
Identity = 26/64 (40.62%), Postives = 37/64 (57.81%), Query Frame = 1

Query:   88 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*L 279
            +L    E +C  P E G C+ +  R++FN + G C  F YGGC GN+N+F+T  EC   C + L
Sbjct: 1074 NLAAQIEEKCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCARFL 1137

HSP 4 Score: 53.1434 bits (126), Expect = 3.130e-9
Identity = 24/51 (47.06%), Postives = 34/51 (66.67%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            CSLPKE G C  Y  R++FN +  +C+ F +GGC+GN+NNF    +C + C
Sbjct:  539 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 5 Score: 52.7582 bits (125), Expect = 4.355e-9
Identity = 26/51 (50.98%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
             SLP   G C G F RYF+NE++ KCE+F Y GC GN NN+ +   C  RC
Sbjct:  426 VSLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 6 Score: 50.8322 bits (120), Expect = 2.020e-8
Identity = 24/51 (47.06%), Postives = 28/51 (54.90%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C    EVG C G F R+ F++    C  F YGGC GN NNF T  EC  +C
Sbjct:  866 CEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 916

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 64.6994 bits (156), Expect = 3.306e-13
Identity = 25/51 (49.02%), Postives = 36/51 (70.59%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C++P + G+C  Y PR+FFN +TG+CE+F YG C GN+NNF+    C  +C
Sbjct: 1651 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 1701

HSP 2 Score: 57.3806 bits (137), Expect = 1.276e-10
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C  P++ G CRG F R+FF++E   C+ F Y GCQGN NNF +  EC A C +
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 789

HSP 3 Score: 55.0694 bits (131), Expect = 8.242e-10
Identity = 27/68 (39.71%), Postives = 40/68 (58.82%), Query Frame = 1

Query:   88 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*LLNIY 291
            +L    E +C  P E G C+ +  R++FN + G C  F YGGC GN+N+F+T  EC   C +  L+I+
Sbjct: 1074 NLAAQIEEKCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR-FLSIH 1140

HSP 4 Score: 53.1434 bits (126), Expect = 2.885e-9
Identity = 24/51 (47.06%), Postives = 34/51 (66.67%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            CSLPKE G C  Y  R++FN +  +C+ F +GGC+GN+NNF    +C + C
Sbjct:  539 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 5 Score: 52.7582 bits (125), Expect = 4.828e-9
Identity = 26/51 (50.98%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
             SLP   G C G F RYF+NE++ KCE+F Y GC GN NN+ +   C  RC
Sbjct:  426 VSLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 6 Score: 51.2174 bits (121), Expect = 1.690e-8
Identity = 24/51 (47.06%), Postives = 28/51 (54.90%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C    EVG C G F R+ F++    C  F YGGC GN NNF T  EC  +C
Sbjct:  866 CEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 916

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 64.6994 bits (156), Expect = 3.318e-13
Identity = 25/51 (49.02%), Postives = 36/51 (70.59%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C++P + G+C  Y PR+FFN +TG+CE+F YG C GN+NNF+    C  +C
Sbjct: 2168 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2218

HSP 2 Score: 56.9954 bits (136), Expect = 1.454e-10
Identity = 26/51 (50.98%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C  P++ G CRG F R+FF++E   C+ F Y GCQGN NNF +  EC A C
Sbjct:  728 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 778

HSP 3 Score: 54.299 bits (129), Expect = 1.244e-9
Identity = 26/64 (40.62%), Postives = 37/64 (57.81%), Query Frame = 1

Query:   88 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*L 279
            +L    E +C  P E G C+ +  R++FN + G C  F YGGC GN+N+F+T  EC   C + L
Sbjct: 1065 NLAAQIEEKCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCARFL 1128

HSP 4 Score: 53.1434 bits (126), Expect = 3.070e-9
Identity = 24/51 (47.06%), Postives = 34/51 (66.67%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            CSLPKE G C  Y  R++FN +  +C+ F +GGC+GN+NNF    +C + C
Sbjct:  539 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 5 Score: 52.7582 bits (125), Expect = 4.271e-9
Identity = 26/51 (50.98%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
             SLP   G C G F RYF+NE++ KCE+F Y GC GN NN+ +   C  RC
Sbjct:  426 VSLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 6 Score: 50.8322 bits (120), Expect = 2.039e-8
Identity = 24/51 (47.06%), Postives = 28/51 (54.90%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C    EVG C G F R+ F++    C  F YGGC GN NNF T  EC  +C
Sbjct:  857 CEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 907

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 64.6994 bits (156), Expect = 3.414e-13
Identity = 25/51 (49.02%), Postives = 36/51 (70.59%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C++P + G+C  Y PR+FFN +TG+CE+F YG C GN+NNF+    C  +C
Sbjct: 2048 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2098

HSP 2 Score: 56.9954 bits (136), Expect = 1.438e-10
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C  P++ G CRG F R+FF++E   C+ F Y GCQGN NNF +  EC A C +
Sbjct:  608 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 660

HSP 3 Score: 54.299 bits (129), Expect = 1.196e-9
Identity = 26/64 (40.62%), Postives = 37/64 (57.81%), Query Frame = 1

Query:   88 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*L 279
            +L    E +C  P E G C+ +  R++FN + G C  F YGGC GN+N+F+T  EC   C + L
Sbjct:  945 NLAAQIEEKCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCARFL 1008

HSP 4 Score: 53.1434 bits (126), Expect = 3.067e-9
Identity = 24/51 (47.06%), Postives = 34/51 (66.67%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            CSLPKE G C  Y  R++FN +  +C+ F +GGC+GN+NNF    +C + C
Sbjct:  410 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 460

HSP 5 Score: 52.7582 bits (125), Expect = 4.394e-9
Identity = 26/51 (50.98%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
             SLP   G C G F RYF+NE++ KCE+F Y GC GN NN+ +   C  RC
Sbjct:  297 VSLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 344

HSP 6 Score: 50.8322 bits (120), Expect = 2.018e-8
Identity = 24/51 (47.06%), Postives = 28/51 (54.90%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C    EVG C G F R+ F++    C  F YGGC GN NNF T  EC  +C
Sbjct:  737 CEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 787

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3f.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 64.6994 bits (156), Expect = 3.430e-13
Identity = 25/51 (49.02%), Postives = 36/51 (70.59%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C++P + G+C  Y PR+FFN +TG+CE+F YG C GN+NNF+    C  +C
Sbjct: 1430 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 1480

HSP 2 Score: 57.3806 bits (137), Expect = 1.202e-10
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C  P++ G CRG F R+FF++E   C+ F Y GCQGN NNF +  EC A C +
Sbjct:  516 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 568

HSP 3 Score: 55.0694 bits (131), Expect = 8.067e-10
Identity = 27/68 (39.71%), Postives = 40/68 (58.82%), Query Frame = 1

Query:   88 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*LLNIY 291
            +L    E +C  P E G C+ +  R++FN + G C  F YGGC GN+N+F+T  EC   C +  L+I+
Sbjct:  853 NLAAQIEEKCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR-FLSIH 919

HSP 4 Score: 53.1434 bits (126), Expect = 2.908e-9
Identity = 24/51 (47.06%), Postives = 34/51 (66.67%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            CSLPKE G C  Y  R++FN +  +C+ F +GGC+GN+NNF    +C + C
Sbjct:  318 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 368

HSP 5 Score: 52.7582 bits (125), Expect = 5.107e-9
Identity = 26/50 (52.00%), Postives = 32/50 (64.00%), Query Frame = 1

Query:  118 SLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            SLP   G C G F RYF+NE++ KCE+F Y GC GN NN+ +   C  RC
Sbjct:  206 SLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 252

HSP 6 Score: 51.2174 bits (121), Expect = 1.606e-8
Identity = 24/51 (47.06%), Postives = 28/51 (54.90%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C    EVG C G F R+ F++    C  F YGGC GN NNF T  EC  +C
Sbjct:  645 CEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 695

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Fly
Match: CG15418 (gene:FBgn0031554 transcript:FBtr0077556)

HSP 1 Score: 59.6918 bits (143), Expect = 8.967e-13
Identity = 30/55 (54.55%), Postives = 35/55 (63.64%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*L 279
            C  PK  GLCRG+  RY +N++TG CE FIY GC   +NNF T  ECR  C Q L
Sbjct:   41 CRQPKAPGLCRGHQLRYAYNKKTGNCESFIYTGCASTENNFLTFEECRRDCMQRL 95

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Fly
Match: CG15418 (gene:FBgn0031554 transcript:FBtr0446100)

HSP 1 Score: 59.6918 bits (143), Expect = 8.967e-13
Identity = 30/55 (54.55%), Postives = 35/55 (63.64%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*L 279
            C  PK  GLCRG+  RY +N++TG CE FIY GC   +NNF T  ECR  C Q L
Sbjct:   41 CRQPKAPGLCRGHQLRYAYNKKTGNCESFIYTGCASTENNFLTFEECRRDCMQRL 95

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0077545)

HSP 1 Score: 58.9214 bits (141), Expect = 4.535e-12
Identity = 26/52 (50.00%), Postives = 33/52 (63.46%), Query Frame = 1

Query:  112 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            +C  PKE G C   F RY +N +T  CE+F+YGGC GNKNNF +  +C   C
Sbjct:   54 DCHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQAC 105

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0346581)

HSP 1 Score: 58.9214 bits (141), Expect = 4.535e-12
Identity = 26/52 (50.00%), Postives = 33/52 (63.46%), Query Frame = 1

Query:  112 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            +C  PKE G C   F RY +N +T  CE+F+YGGC GNKNNF +  +C   C
Sbjct:   54 DCHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQAC 105

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Fly
Match: Ppn (gene:FBgn0003137 transcript:FBtr0300337)

HSP 1 Score: 56.9954 bits (136), Expect = 1.866e-10
Identity = 24/53 (45.28%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C LPKE G C  Y  +Y+F+   G C +F YGGC GN N F +  EC+  C+ 
Sbjct: 1612 CGLPKETGTCNNYSVKYYFDTSYGGCARFWYGGCDGNDNRFESEAECKDTCQD 1664

HSP 2 Score: 56.225 bits (134), Expect = 3.310e-10
Identity = 26/55 (47.27%), Postives = 32/55 (58.18%), Query Frame = 1

Query:  109 PECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            P C  P E G C G F R++++ ET  C  F YGGC+GNKNN+ T   C   C Q
Sbjct: 1728 PTCEQPVESGPCAGNFERWYYDNETDICRPFTYGGCKGNKNNYPTEHACNYNCRQ 1782

HSP 3 Score: 48.1358 bits (113), Expect = 2.716e-7
Identity = 20/51 (39.22%), Postives = 31/51 (60.78%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C LPK  G C G+  +++F+ +  +CE+F YGGC G  N F +  +C+  C
Sbjct: 1671 CLLPKSAGPCTGFTKKWYFDVDRNRCEEFQYGGCYGTNNRFDSLEQCQGTC 1721

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Zebrafish
Match: spint2 (serine peptidase inhibitor, Kunitz type, 2 [Source:ZFIN;Acc:ZDB-GENE-061013-323])

HSP 1 Score: 62.7734 bits (151), Expect = 2.033e-12
Identity = 27/51 (52.94%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C  P  VG CR  FPR+F++     C+ FIYGGC GN+NNFY+  EC A C
Sbjct:  133 CRFPSAVGNCRAAFPRFFYDITDQTCKSFIYGGCGGNENNFYSQAECEASC 183

HSP 2 Score: 50.0618 bits (118), Expect = 6.747e-8
Identity = 22/54 (40.74%), Postives = 32/54 (59.26%), Query Frame = 1

Query:  106 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            E +C +P + G CR  F  +FF   +  C+ FIYGGC+GN N + +  EC + C
Sbjct:  301 EEKCVVPSDSGPCRASFRMFFFEASSQSCQPFIYGGCRGNLNRYGSEEECMSVC 354

HSP 3 Score: 48.1358 bits (113), Expect = 2.627e-7
Identity = 22/54 (40.74%), Postives = 31/54 (57.41%), Query Frame = 1

Query:  106 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            + +C  P   G CR    R+++N   G C++FIYGGC GNKNN+ +   C   C
Sbjct:  225 QEKCQSPAVTGNCRASIKRFYYN--NGVCQQFIYGGCGGNKNNYESEDSCMTAC 276

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Zebrafish
Match: spint2 (serine peptidase inhibitor, Kunitz type, 2 [Source:ZFIN;Acc:ZDB-GENE-061013-323])

HSP 1 Score: 62.7734 bits (151), Expect = 2.053e-12
Identity = 27/51 (52.94%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C  P  VG CR  FPR+F++     C+ FIYGGC GN+NNFY+  EC A C
Sbjct:  133 CRFPSAVGNCRAAFPRFFYDITDQTCKSFIYGGCGGNENNFYSQAECEASC 183

HSP 2 Score: 50.0618 bits (118), Expect = 6.813e-8
Identity = 22/54 (40.74%), Postives = 32/54 (59.26%), Query Frame = 1

Query:  106 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            E +C +P + G CR  F  +FF   +  C+ FIYGGC+GN N + +  EC + C
Sbjct:  301 EEKCVVPSDSGPCRASFRMFFFEASSQSCQPFIYGGCRGNLNRYGSEEECMSVC 354

HSP 3 Score: 48.1358 bits (113), Expect = 2.679e-7
Identity = 22/54 (40.74%), Postives = 31/54 (57.41%), Query Frame = 1

Query:  106 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            + +C  P   G CR    R+++N   G C++FIYGGC GNKNN+ +   C   C
Sbjct:  225 QEKCQSPAVTGNCRASIKRFYYN--NGVCQQFIYGGCGGNKNNYESEDSCMTAC 276

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Zebrafish
Match: wfikkn1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 [Source:NCBI gene;Acc:406570])

HSP 1 Score: 61.6178 bits (148), Expect = 5.205e-12
Identity = 28/51 (54.90%), Postives = 34/51 (66.67%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            CSLP   G CR +  R+F+N  T +CE F+YGGC GNKN+F T  EC A C
Sbjct:  257 CSLPAVQGPCRHWQARWFYNSLTERCEAFLYGGCSGNKNSFGTRRECDAHC 307

HSP 2 Score: 43.8986 bits (102), Expect = 8.519e-6
Identity = 22/54 (40.74%), Postives = 31/54 (57.41%), Query Frame = 1

Query:  112 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            +CS   E G C      +FF+   G C  F +GGC+G +N F+T  ECRA C++
Sbjct:  199 DCSAAVERGDCGEKRVDWFFDPARGSCHTFTHGGCEG-RNRFHTFEECRASCQR 251

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Zebrafish
Match: aplp2 (amyloid beta (A4) precursor-like protein 2 [Source:ZFIN;Acc:ZDB-GENE-061009-28])

HSP 1 Score: 61.2326 bits (147), Expect = 8.087e-12
Identity = 26/56 (46.43%), Postives = 34/56 (60.71%), Query Frame = 1

Query:  106 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            E  CSL  E G CR   PR+ F+ +  KC +FIYGGC GN+NNF +   C   C++
Sbjct:  312 EAVCSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMVVCKR 367

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Zebrafish
Match: aplp2 (amyloid beta (A4) precursor-like protein 2 [Source:ZFIN;Acc:ZDB-GENE-061009-28])

HSP 1 Score: 60.8474 bits (146), Expect = 9.834e-12
Identity = 26/56 (46.43%), Postives = 34/56 (60.71%), Query Frame = 1

Query:  106 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            E  CSL  E G CR   PR+ F+ +  KC +FIYGGC GN+NNF +   C   C++
Sbjct:  312 EAVCSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMVVCKR 367

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Xenopus
Match: itch (itchy E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-976485])

HSP 1 Score: 60.4622 bits (145), Expect = 2.457e-11
Identity = 25/54 (46.30%), Postives = 34/54 (62.96%), Query Frame = 1

Query:  109 PE-CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            PE C+L KE G CR +  +++++ ET  C +F YGGC GN+N F T  EC   C
Sbjct: 2826 PEVCNLQKEEGTCRDFVLKWYYDPETKSCARFWYGGCGGNENRFSTQKECEKIC 2879

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Xenopus
Match: itch (itchy E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-976485])

HSP 1 Score: 60.4622 bits (145), Expect = 2.459e-11
Identity = 25/54 (46.30%), Postives = 34/54 (62.96%), Query Frame = 1

Query:  109 PE-CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            PE C+L KE G CR +  +++++ ET  C +F YGGC GN+N F T  EC   C
Sbjct: 3006 PEVCNLQKEEGTCRDFVLKWYYDPETKSCARFWYGGCGGNENRFSTQKECEKIC 3059

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Xenopus
Match: itch (itchy E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-976485])

HSP 1 Score: 60.4622 bits (145), Expect = 2.460e-11
Identity = 25/54 (46.30%), Postives = 34/54 (62.96%), Query Frame = 1

Query:  109 PE-CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            PE C+L KE G CR +  +++++ ET  C +F YGGC GN+N F T  EC   C
Sbjct: 3023 PEVCNLQKEEGTCRDFVLKWYYDPETKSCARFWYGGCGGNENRFSTQKECEKIC 3076

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Xenopus
Match: PAPLN (papilin, proteoglycan-like sulfated glycoprotein [Source:NCBI gene;Acc:100489537])

HSP 1 Score: 59.6918 bits (143), Expect = 3.388e-11
Identity = 26/53 (49.06%), Postives = 32/53 (60.38%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C LP   G C  +  R++F  E GKC +F YG C GNKNNF T  EC + C+Q
Sbjct:  666 CLLPSATGSCADWSTRWYFVPEVGKCNRFWYGNCHGNKNNFATEQECMSSCQQ 718

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Xenopus
Match: PAPLN (papilin, proteoglycan-like sulfated glycoprotein [Source:NCBI gene;Acc:100489537])

HSP 1 Score: 59.6918 bits (143), Expect = 3.694e-11
Identity = 26/53 (49.06%), Postives = 32/53 (60.38%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C LP   G C  +  R++F  E GKC +F YG C GNKNNF T  EC + C+Q
Sbjct:  646 CLLPSATGSCADWSTRWYFVPEVGKCNRFWYGNCHGNKNNFATEQECMSSCQQ 698

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Mouse
Match: Spint3 (serine peptidase inhibitor, Kunitz type, 3 [Source:MGI Symbol;Acc:MGI:3651470])

HSP 1 Score: 65.855 bits (159), Expect = 4.152e-15
Identity = 29/53 (54.72%), Postives = 40/53 (75.47%), Query Frame = 1

Query:  109 PECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            P C LPK++G CR  F R+++N +TGKCE F YGGC+GN+NNF +  +C+A C
Sbjct:   33 PMCILPKDIGGCRAVFVRWYYNSKTGKCEWFRYGGCKGNENNFPSRSQCQAVC 85

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Mouse
Match: Eppin (epididymal peptidase inhibitor [Source:MGI Symbol;Acc:MGI:1922776])

HSP 1 Score: 65.855 bits (159), Expect = 1.112e-14
Identity = 29/57 (50.88%), Postives = 39/57 (68.42%), Query Frame = 1

Query:  103 KEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            ++  CSLPK+ G C  YF R++FN+E   C+ FIYGGCQGN NNF +   C+  CE+
Sbjct:   73 QQDICSLPKDSGYCMAYFRRWWFNKENSTCQVFIYGGCQGNNNNFQSQSICQNACEK 129

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Mouse
Match: Tfpi (tissue factor pathway inhibitor [Source:MGI Symbol;Acc:MGI:1095418])

HSP 1 Score: 66.6254 bits (161), Expect = 3.922e-14
Identity = 29/53 (54.72%), Postives = 38/53 (71.70%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C L ++ GLCRGY  RY +N +T +CE+F+YGGC GN+NNF T  EC+  CE 
Sbjct:  121 CFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKICEN 173

HSP 2 Score: 53.5286 bits (127), Expect = 2.429e-9
Identity = 24/51 (47.06%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C++  + G C+     YFFN  T +CE+FIYGGC+GN+N F T  EC+  C
Sbjct:   50 CAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTC 100

[Close]

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C L ++ GLCRGY  RY +N +T +CE+F+YGGC GN+NNF T  EC+  CE 
Sbjct:  121 CFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKICEN 173

HSP 2 Score: 53.5286 bits (127), Expect = 2.429e-9
Identity = 24/51 (47.06%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C++  + G C+     YFFN  T +CE+FIYGGC+GN+N F T  EC+  C
Sbjct:   50 CAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTC 100

[Close]

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C L ++ GLCRGY  RY +N +T +CE+F+YGGC GN+NNF T  EC+  CE 
Sbjct:  121 CFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKICEN 173

HSP 2 Score: 53.5286 bits (127), Expect = 2.429e-9
Identity = 24/51 (47.06%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C++  + G C+     YFFN  T +CE+FIYGGC+GN+N F T  EC+  C
Sbjct:   50 CAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTC 100

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. UniProt/SwissProt
Match: sp|P0DMW6|VKT3A_ACTEQ (PI-actitoxin-Aeq3a OS=Actinia equina OX=6106 PE=1 SV=1)

HSP 1 Score: 76.2554 bits (186), Expect = 1.125e-18
Identity = 34/53 (64.15%), Postives = 40/53 (75.47%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C LP  VG CRGYFPRY++N E GKC++FIYGGC GN+NNF T  +CRA C  
Sbjct:    6 CQLPAVVGKCRGYFPRYYYNTEAGKCQQFIYGGCGGNRNNFETVEDCRATCHS 58

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. UniProt/SwissProt
Match: sp|P0DMW7|VKT3B_ACTEQ (PI-actitoxin-Aeq3b OS=Actinia equina OX=6106 PE=1 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 3.820e-18
Identity = 33/53 (62.26%), Postives = 40/53 (75.47%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C LP  VG CRGYFPR+++N E GKC++FIYGGC GN+NNF T  +CRA C  
Sbjct:    6 CQLPAVVGKCRGYFPRFYYNTEAGKCQQFIYGGCGGNRNNFETVEDCRATCHS 58

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. UniProt/SwissProt
Match: sp|P0DMX0|VKT3_ANTAF (PI-actitoxin-Axm2b OS=Anthopleura aff. xanthogrammica OX=152178 PE=1 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 5.813e-17
Identity = 34/51 (66.67%), Postives = 39/51 (76.47%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C LP   G CRGYFPRYFF+ ETGKCE+FIYGGC GN+NNF +  EC + C
Sbjct:    7 CYLPAVRGRCRGYFPRYFFSSETGKCERFIYGGCGGNRNNFESAQECGSTC 57

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. UniProt/SwissProt
Match: sp|P0DJ50|VKT31_MESMA (Kunitz-type serine protease inhibitor BmKTT-2 OS=Mesobuthus martensii OX=34649 PE=2 SV=2)

HSP 1 Score: 71.633 bits (174), Expect = 1.387e-16
Identity = 28/60 (46.67%), Postives = 43/60 (71.67%), Query Frame = 1

Query:   91 LGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCE 270
            + D +  +C+LP + G C+ YF RYF+N++ G+C+KF+YGGC+GN NNF T  +C  +C 
Sbjct:   18 ISDAEGVDCTLPSDTGRCKAYFIRYFYNQKAGECQKFVYGGCEGNSNNFLTKSDCCKQCS 77

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. UniProt/SwissProt
Match: sp|B1B5I8|VKT3_STIHA (KappaPI-stichotoxin-Shd2a OS=Stichodactyla haddoni OX=475174 PE=1 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 6.724e-16
Identity = 33/51 (64.71%), Postives = 38/51 (74.51%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C L  +V  CRGYFPRY++N E GKCE+FIYGGC GNKNNF +   CRA C
Sbjct:   27 CHLQPDVPKCRGYFPRYYYNPEVGKCEQFIYGGCGGNKNNFVSFEACRATC 77

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. TrEMBL
Match: I1ZII0 (Serine protease inhibitor-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 9.339e-16
Identity = 33/59 (55.93%), Postives = 42/59 (71.19%), Query Frame = 1

Query:   97 DCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
             C    CSLPK  G C+ YFPRY++N +TGKCEKFIYGGC+GN+NNF +  +C   C +
Sbjct:   17 SCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 75

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. TrEMBL
Match: A7T2J6 (Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g143195 PE=4 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 4.730e-15
Identity = 32/53 (60.38%), Postives = 38/53 (71.70%), Query Frame = 1

Query:  109 PECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
              C+LPK+VG CR   PR FFN ++GKCE FIYGGC GN NNF+T  EC+  C
Sbjct:   12 SACTLPKKVGDCRAAMPRVFFNSQSGKCEDFIYGGCGGNANNFHTMEECKKAC 64

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. TrEMBL
Match: A0A1V0FWP9 (Venom kunitz type-like peptide Vf1 (Fragment) OS=Viridasius fasciatus OX=1971609 PE=2 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 6.095e-15
Identity = 31/51 (60.78%), Postives = 40/51 (78.43%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C LP E G+CRG+FPRY+F+  TG+C+KF+YGGC GN+NNF T  EC+  C
Sbjct:    9 CDLPAETGVCRGFFPRYYFDRTTGQCQKFVYGGCGGNENNFETVEECQRTC 59

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. TrEMBL
Match: H9GVB9 (Tissue factor pathway inhibitor OS=Anolis carolinensis OX=28377 PE=4 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 8.129e-15
Identity = 35/61 (57.38%), Postives = 45/61 (73.77%), Query Frame = 1

Query:  103 KEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*LLN 285
            +E  CSLPK+ GLCR  F R++FN ETG+CE F YGGC+GN NNF T  EC ++CE  ++N
Sbjct:   64 QETICSLPKKTGLCRAAFHRFYFNSETGQCESFTYGGCEGNANNFLTWDECFSKCEGFIVN 124

HSP 2 Score: 55.8398 bits (133), Expect = 6.947e-7
Identity = 25/51 (49.02%), Postives = 34/51 (66.67%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            CSLP+E G CR  F R++F+ ++G+CE F Y G  GN NNF T  +C  +C
Sbjct:  177 CSLPRETGRCRRSFRRFYFDSKSGQCESFRYSGRGGNANNFLTQDDCVTKC 227

HSP 3 Score: 53.5286 bits (127), Expect = 4.606e-6
Identity = 23/44 (52.27%), Postives = 28/44 (63.64%), Query Frame = 1

Query:  136 GLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            G C GYFP Y++N E   C+ FIY GC GN NNF++  EC   C
Sbjct:    2 GFCNGYFPHYYYNAENKTCQLFIYNGCGGNDNNFHSVRECLQTC 45

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. TrEMBL
Match: A0A2T7PBH0 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_10027 PE=4 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 2.701e-14
Identity = 32/53 (60.38%), Postives = 39/53 (73.58%), Query Frame = 1

Query:  109 PECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            P CSLP E G C+ YFPR++FN  TG CE+FIYGGC GN NN+ T  +C+A C
Sbjct:  148 PACSLPSETGPCKAYFPRFYFNTNTGSCEQFIYGGCDGNDNNYLTVEDCQATC 200

HSP 2 Score: 58.151 bits (139), Expect = 7.286e-8
Identity = 27/51 (52.94%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C+ P  +G CRG F RYFFN+ +  CE FIYGGC  N NNF T  +C+  C
Sbjct:   22 CTDPAIIGPCRGQFYRYFFNQISQSCELFIYGGCGANDNNFLTLEDCQTAC 72

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Cavefish
Match: lrp11 (LDL receptor related protein 11 [Source:NCBI gene;Acc:103032685])

HSP 1 Score: 64.3142 bits (155), Expect = 6.178e-13
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C  P  VG CRG FPR++++   G+C+ F+YGGC+GN+NNF    +C   C Q
Sbjct:  417 CMEPPVVGPCRGTFPRWYYDAAAGECKHFLYGGCKGNRNNFLQQTDCVNECIQ 469

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Cavefish
Match: lrp11 (LDL receptor related protein 11 [Source:NCBI gene;Acc:103032685])

HSP 1 Score: 63.1586 bits (152), Expect = 1.459e-12
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C  P  VG CRG FPR++++   G+C+ F+YGGC+GN+NNF    +C   C Q
Sbjct:  417 CMEPPVVGPCRGTFPRWYYDAAAGECKHFLYGGCKGNRNNFLQQTDCVNECIQ 469

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Cavefish
Match: aplp2 (amyloid beta precursor like protein 2 [Source:NCBI gene;Acc:103022515])

HSP 1 Score: 62.003 bits (149), Expect = 3.718e-12
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            CSL  E G CR   PR+ F+ +  KC +FIYGGC GN+NNF +   C A C++
Sbjct:  315 CSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMAVCKR 367

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Cavefish
Match: aplp2 (amyloid beta precursor like protein 2 [Source:NCBI gene;Acc:103022515])

HSP 1 Score: 61.6178 bits (148), Expect = 4.434e-12
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            CSL  E G CR   PR+ F+ +  KC +FIYGGC GN+NNF +   C A C++
Sbjct:  315 CSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMAVCKR 367

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Cavefish
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:NCBI gene;Acc:103023332])

HSP 1 Score: 60.077 bits (144), Expect = 6.032e-12
Identity = 28/51 (54.90%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C  P EVG CR    RYFFN  T +CE+F YGGCQGN+NNF +   C   C
Sbjct:   87 CRFPSEVGPCRALLSRYFFNMTTMQCEQFYYGGCQGNENNFQSHQSCMEYC 137

HSP 2 Score: 56.225 bits (134), Expect = 1.624e-10
Identity = 28/51 (54.90%), Postives = 31/51 (60.78%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C LP   G CRG   RYF+N  T +CE+F YGGC GN NNF T  EC   C
Sbjct:   27 CLLPAVEGPCRGLVSRYFYNTLTQRCEEFSYGGCGGNANNFVTFQECHKMC 77

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Sea Lamprey
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:ZFIN;Acc:ZDB-GENE-060503-38])

HSP 1 Score: 69.707 bits (169), Expect = 4.945e-16
Identity = 32/56 (57.14%), Postives = 37/56 (66.07%), Query Frame = 1

Query:  103 KEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCE 270
            +   C+LP + G CR  FPRYFFN  T +CE FIYGGC  N+NNF T  ECRA C 
Sbjct:   23 QRVTCTLPAKPGDCRAAFPRYFFNRSTLRCESFIYGGCHSNENNFETMQECRAACS 78

HSP 2 Score: 45.8246 bits (107), Expect = 2.235e-7
Identity = 22/51 (43.14%), Postives = 25/51 (49.02%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C    E G CR +  RYF+N   G C  F+YGGC GN N F     C   C
Sbjct:   87 CRPDAETGRCRAHITRYFYNMTLGMCMPFVYGGCGGNNNRFEDMESCVFSC 137

HSP 3 Score: 42.743 bits (99), Expect = 3.231e-6
Identity = 20/52 (38.46%), Postives = 28/52 (53.85%), Query Frame = 1

Query:  112 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            EC    + G C+G F R+++N +   C  F Y GC GN NNF +   C + C
Sbjct:  146 ECLSRHDTGNCQGNFRRFYYNIQKRSCLPFSYSGCGGNNNNFISAKTCLSTC 197

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005038.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005038.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.8474 bits (146), Expect = 8.568e-13
Identity = 29/57 (50.88%), Postives = 32/57 (56.14%), Query Frame = 1

Query:   97 DCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            D     C L  EVG+CR    RYFFN  +G CE+F YGGCQGN NNF     C   C
Sbjct:   69 DIAPKACRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHC 125

HSP 2 Score: 55.8398 bits (133), Expect = 6.498e-11
Identity = 26/52 (50.00%), Postives = 32/52 (61.54%), Query Frame = 1

Query:  112 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
             C +  + G CR Y PR F+N  T +CE F YGGC GN NNF +  EC A+C
Sbjct:    2 SCMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKC 53

HSP 3 Score: 49.2914 bits (116), Expect = 1.207e-8
Identity = 22/53 (41.51%), Postives = 29/53 (54.72%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C +  + G C    PR+ +N +T  CE F YGGC GN NNF +   C + C Q
Sbjct:  167 CLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVCGQ 219

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005043.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005043.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.6918 bits (143), Expect = 2.302e-12
Identity = 28/51 (54.90%), Postives = 31/51 (60.78%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C L  EVG+CR    RYFFN  +G CE+F YGGCQGN NNF     C   C
Sbjct:   74 CRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHC 124

HSP 2 Score: 55.4546 bits (132), Expect = 7.206e-11
Identity = 26/52 (50.00%), Postives = 32/52 (61.54%), Query Frame = 1

Query:  112 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
             C +  + G CR Y PR F+N  T +CE F YGGC GN NNF +  EC A+C
Sbjct:    2 SCMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKC 53

HSP 3 Score: 49.2914 bits (116), Expect = 1.176e-8
Identity = 22/53 (41.51%), Postives = 29/53 (54.72%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C +  + G C    PR+ +N +T  CE F YGGC GN NNF +   C + C Q
Sbjct:  166 CLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVCGQ 218

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009465.1 (pep scaffold:Pmarinus_7.0:GL478507:22936:25713:-1 gene:ENSPMAG00000008558.1 transcript:ENSPMAT00000009465.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.5286 bits (127), Expect = 4.216e-10
Identity = 24/51 (47.06%), Postives = 31/51 (60.78%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C L + VG CRG F R+ ++ E+  C++F YGGC GN NNF    EC   C
Sbjct:   72 CLLEEAVGPCRGSFTRWIYDAESSNCKEFTYGGCGGNFNNFLEETECMVTC 122

HSP 2 Score: 51.6026 bits (122), Expect = 2.296e-9
Identity = 24/54 (44.44%), Postives = 31/54 (57.41%), Query Frame = 1

Query:  106 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            +  C L      CRG F R+ ++ E+G C++F YGGC GN NNF    EC A C
Sbjct:  163 QDVCLLEAVTSPCRGSFTRWTYDAESGHCKEFTYGGCGGNFNNFLEETECVAMC 216

HSP 3 Score: 51.2174 bits (121), Expect = 3.384e-9
Identity = 23/51 (45.10%), Postives = 30/51 (58.82%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C L    G CRG F R+ ++  T  C++F YGGC+GN+NNF    EC   C
Sbjct:    1 CLLNPTTGPCRGSFTRWTYDAATSTCKEFTYGGCRGNQNNFLEEAECLMDC 51

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Sea Lamprey
Match: WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30912])

HSP 1 Score: 50.8322 bits (120), Expect = 5.682e-9
Identity = 22/51 (43.14%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            CSLP + G C+ +  R+ +N    +C+ FIYGGC+GN+NNF +   C   C
Sbjct:  374 CSLPVQQGPCKQWALRWAYNPLIKRCQSFIYGGCEGNENNFQSQELCEDNC 424

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Nematostella
Match: EDO29819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2J6])

HSP 1 Score: 73.559 bits (179), Expect = 6.541e-19
Identity = 32/53 (60.38%), Postives = 38/53 (71.70%), Query Frame = 1

Query:  109 PECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
              C+LPK+VG CR   PR FFN ++GKCE FIYGGC GN NNF+T  EC+  C
Sbjct:   12 SACTLPKKVGDCRAAMPRVFFNSQSGKCEDFIYGGCGGNANNFHTMEECKKAC 64

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Nematostella
Match: EDO41696 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 64.6994 bits (156), Expect = 1.345e-15
Identity = 28/52 (53.85%), Postives = 37/52 (71.15%), Query Frame = 1

Query:  112 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            EC  PK  G CR YF R+F+N+ + KC++F+YGGCQGN NNF +  EC  +C
Sbjct:    1 ECLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Nematostella
Match: EDO26263 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 64.6994 bits (156), Expect = 1.345e-15
Identity = 28/52 (53.85%), Postives = 37/52 (71.15%), Query Frame = 1

Query:  112 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            EC  PK  G CR YF R+F+N+ + KC++F+YGGCQGN NNF +  EC  +C
Sbjct:    1 ECLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Nematostella
Match: EDO49645 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFR1])

HSP 1 Score: 62.003 bits (149), Expect = 1.913e-14
Identity = 28/57 (49.12%), Postives = 35/57 (61.40%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*LLN 285
            C LPKE GLC G F ++F+N     C+KF YGGC GN N F T   C+  C+  LL+
Sbjct:    4 CQLPKEAGLCEGLFTKWFYNATANHCQKFTYGGCGGNANRFDTKRACKLACKGILLS 60

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Nematostella
Match: EDO31760 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX09])

HSP 1 Score: 59.3066 bits (142), Expect = 2.163e-13
Identity = 27/51 (52.94%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C LPK  G+CR    R+++N ET KC KF +GGC GN NNF T   CR  C
Sbjct:    1 CDLPKNPGVCRASIQRWYYNNETRKCIKFTFGGCHGNANNFPTKSSCRNAC 51

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Medaka
Match: ENSORLT00000012975.2 (pep primary_assembly:ASM223467v1:12:15740273:15760140:1 gene:ENSORLG00000010354.2 transcript:ENSORLT00000012975.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.5438 bits (153), Expect = 1.770e-13
Identity = 30/51 (58.82%), Postives = 35/51 (68.63%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C+   + GLC GYF RYF+N   G+CE FIYGGC GN+NNF T  EC  RC
Sbjct:  125 CAQAPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQRC 175

HSP 2 Score: 61.2326 bits (147), Expect = 1.677e-12
Identity = 29/50 (58.00%), Postives = 34/50 (68.00%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRAR 264
            C+   + GLC GYF RYF+N   G+CE FIYGGC GN+NNF T  EC  R
Sbjct:   73 CAQAPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQR 122

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Medaka
Match: lrp11 (low-density lipoprotein receptor-related protein 11 [Source:NCBI gene;Acc:101175213])

HSP 1 Score: 64.6994 bits (156), Expect = 3.715e-13
Identity = 25/53 (47.17%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            C     VG C+G FPR+++++ TG+C+ F+YGGCQGN NNF   ++C + C Q
Sbjct:  394 CGADPVVGPCKGTFPRWYYDQNTGECKHFLYGGCQGNHNNFLQELDCISECIQ 446

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Medaka
Match: ENSORLT00000042019.1 (pep primary_assembly:ASM223467v1:12:15740119:15780496:1 gene:ENSORLG00000010354.2 transcript:ENSORLT00000042019.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.5438 bits (153), Expect = 4.755e-13
Identity = 31/54 (57.41%), Postives = 37/54 (68.52%), Query Frame = 1

Query:  103 KEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRAR 264
            K P+  +P + GLC GYF RYF+N   G+CE FIYGGC GN+NNF T  EC  R
Sbjct:   77 KLPQPHIPPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQR 130

HSP 2 Score: 58.5362 bits (140), Expect = 3.151e-11
Identity = 28/47 (59.57%), Postives = 33/47 (70.21%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIEC 255
            C+   + GLC GYF RYF+N   G+CE FIYGGC GN+NNF T  EC
Sbjct:   25 CAQAPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKEC 71

HSP 3 Score: 50.0618 bits (118), Expect = 4.075e-8
Identity = 26/51 (50.98%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C+L  + G C  Y  RYF+N +  +CE FIYG C GN+NNF T  EC  RC
Sbjct:  133 CTLDPDPGPCECYSERYFYNFKKRRCEIFIYGCCNGNQNNFETEQECLRRC 183

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Medaka
Match: APP (amyloid-beta A4 protein [Source:NCBI gene;Acc:101162104])

HSP 1 Score: 62.7734 bits (151), Expect = 1.667e-12
Identity = 25/51 (49.02%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C    E G CR   PR+FF+ E G+C +FIYGGC GN+NNF +   C + C
Sbjct:  330 CWADAETGPCRALLPRWFFDREEGRCVQFIYGGCGGNRNNFESEEYCMSVC 380

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Medaka
Match: spint1a (kunitz-type protease inhibitor 1 [Source:NCBI gene;Acc:101175207])

HSP 1 Score: 62.7734 bits (151), Expect = 1.932e-12
Identity = 27/51 (52.94%), Postives = 36/51 (70.59%), Query Frame = 1

Query:  115 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
            C +PK+VG CRG FPR+++N  + KCE F +GGC+ NKNN+ T  EC   C
Sbjct:  234 CLVPKKVGPCRGSFPRWYYNAASEKCETFFFGGCRQNKNNYLTEEECAMAC 284

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Planmine SMEST
Match: SMESG000013910.1 (SMESG000013910.1)

HSP 1 Score: 129.798 bits (325), Expect = 8.578e-41
Identity = 62/62 (100.00%), Postives = 62/62 (100.00%), Query Frame = 1

Query:   88 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ
Sbjct:   11 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 72

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Planmine SMEST
Match: SMESG000013915.1 (SMESG000013915.1)

HSP 1 Score: 117.857 bits (294), Expect = 1.037e-35
Identity = 56/60 (93.33%), Postives = 58/60 (96.67%), Query Frame = 1

Query:   94 GDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
            G  ++PECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ
Sbjct:   38 GRVEKPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 97

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Planmine SMEST
Match: SMESG000037994.1 (SMESG000037994.1)

HSP 1 Score: 79.7221 bits (195), Expect = 7.005e-21
Identity = 35/60 (58.33%), Postives = 44/60 (73.33%), Query Frame = 1

Query:   88 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 267
             LG+ + PEC+ PK+ G+C  YFPR++FN ++G CE FIYGGCQ N NNF T  EC ARC
Sbjct:   16 SLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 75

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Planmine SMEST
Match: SMESG000038052.1 (SMESG000038052.1)

HSP 1 Score: 75.0998 bits (183), Expect = 4.373e-19
Identity = 34/62 (54.84%), Postives = 41/62 (66.13%), Query Frame = 1

Query:   88 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
             L + K PEC+LP E GLC  YF RY F+ + GKC  F+YGGC  N NNF+T  EC  RCE+
Sbjct:   16 QLTESKSPECNLPLETGLCEAYFVRYGFDVKLGKCRTFVYGGCHVNDNNFHTRAECEERCEK 77

[Close]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Planmine SMEST
Match: SMESG000038055.1 (SMESG000038055.1)

HSP 1 Score: 72.0182 bits (175), Expect = 7.276e-18
Identity = 34/62 (54.84%), Postives = 41/62 (66.13%), Query Frame = 1

Query:   88 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 273
             L + K PEC+L  E GLCR YF RY F+ + GKC  F+YGGC  N NNF+T  EC  RCE+
Sbjct:   16 QLIEGKAPECNLSLETGLCRAYFVRYGFDVKLGKCRTFVYGGCPVNDNNFHTRAECEERCEK 77

The following BLAST results are available for this feature:

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Human
BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Celegans
BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Fly
BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Zebrafish
BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Xenopus
BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Mouse
BLAST of Kunitz-type serine protease inhibitor 6 vs. UniProt/SwissProt
BLAST of Kunitz-type serine protease inhibitor 6 vs. TrEMBL
BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Cavefish
BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Sea Lamprey
BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Yeast
BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Nematostella
BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Medaka
BLAST of Kunitz-type serine protease inhibitor 6 vs. Planmine SMEST

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TFPI	8.754e-13	54.72	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	8.754e-13	54.72	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	1.035e-12	54.72	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	2.498e-12	54.72	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	2.498e-12	54.72	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mlt-11	3.286e-13	49.02	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	3.306e-13	49.02	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	3.318e-13	49.02	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	3.414e-13	49.02	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	3.430e-13	49.02	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG15418	8.967e-13	54.55	gene:FBgn0031554 transcript:FBtr0077556	[more]
CG15418	8.967e-13	54.55	gene:FBgn0031554 transcript:FBtr0446100	[more]
CG3604	4.535e-12	50.00	gene:FBgn0031562 transcript:FBtr0077545	[more]
CG3604	4.535e-12	50.00	gene:FBgn0031562 transcript:FBtr0346581	[more]
Ppn	1.866e-10	45.28	gene:FBgn0003137 transcript:FBtr0300337	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
spint2	2.033e-12	52.94	serine peptidase inhibitor, Kunitz type, 2 [Source...	[more]
spint2	2.053e-12	52.94	serine peptidase inhibitor, Kunitz type, 2 [Source...	[more]
wfikkn1	5.205e-12	54.90	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
aplp2	8.087e-12	46.43	amyloid beta (A4) precursor-like protein 2 [Source...	[more]
aplp2	9.834e-12	46.43	amyloid beta (A4) precursor-like protein 2 [Source...	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
itch	2.457e-11	46.30	itchy E3 ubiquitin protein ligase [Source:Xenbase;...	[more]
itch	2.459e-11	46.30	itchy E3 ubiquitin protein ligase [Source:Xenbase;...	[more]
itch	2.460e-11	46.30	itchy E3 ubiquitin protein ligase [Source:Xenbase;...	[more]
PAPLN	3.388e-11	49.06	papilin, proteoglycan-like sulfated glycoprotein [...	[more]
PAPLN	3.694e-11	49.06	papilin, proteoglycan-like sulfated glycoprotein [...	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Spint3	4.152e-15	54.72	serine peptidase inhibitor, Kunitz type, 3 [Source...	[more]
Eppin	1.112e-14	50.88	epididymal peptidase inhibitor [Source:MGI Symbol;...	[more]
Tfpi	3.922e-14	54.72	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]
Tfpi	3.922e-14	54.72	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]
Tfpi	3.922e-14	54.72	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P0DMW6\|VKT3A_ACTEQ	1.125e-18	64.15	PI-actitoxin-Aeq3a OS=Actinia equina OX=6106 PE=1 ...	[more]
sp\|P0DMW7\|VKT3B_ACTEQ	3.820e-18	62.26	PI-actitoxin-Aeq3b OS=Actinia equina OX=6106 PE=1 ...	[more]
sp\|P0DMX0\|VKT3_ANTAF	5.813e-17	66.67	PI-actitoxin-Axm2b OS=Anthopleura aff. xanthogramm...	[more]
sp\|P0DJ50\|VKT31_MESMA	1.387e-16	46.67	Kunitz-type serine protease inhibitor BmKTT-2 OS=M...	[more]
sp\|B1B5I8\|VKT3_STIHA	6.724e-16	64.71	KappaPI-stichotoxin-Shd2a OS=Stichodactyla haddoni...	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZII0	9.339e-16	55.93	Serine protease inhibitor-1 (Fragment) OS=Schmidte...	[more]
A7T2J6	4.730e-15	60.38	Predicted protein OS=Nematostella vectensis OX=453...	[more]
A0A1V0FWP9	6.095e-15	60.78	Venom kunitz type-like peptide Vf1 (Fragment) OS=V...	[more]
H9GVB9	8.129e-15	57.38	Tissue factor pathway inhibitor OS=Anolis caroline...	[more]
A0A2T7PBH0	2.701e-14	60.38	Uncharacterized protein OS=Pomacea canaliculata OX...	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrp11	6.178e-13	47.17	LDL receptor related protein 11 [Source:NCBI gene;...	[more]
lrp11	1.459e-12	47.17	LDL receptor related protein 11 [Source:NCBI gene;...	[more]
aplp2	3.718e-12	49.06	amyloid beta precursor like protein 2 [Source:NCBI...	[more]
aplp2	4.434e-12	49.06	amyloid beta precursor like protein 2 [Source:NCBI...	[more]
tfpi2	6.032e-12	54.90	tissue factor pathway inhibitor 2 [Source:NCBI gen...	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfpi2	4.945e-16	57.14	tissue factor pathway inhibitor 2 [Source:ZFIN;Acc...	[more]
ENSPMAT00000005038.1	8.568e-13	50.88	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
ENSPMAT00000005043.1	2.302e-12	54.90	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
ENSPMAT00000009465.1	4.216e-10	47.06	pep scaffold:Pmarinus_7.0:GL478507:22936:25713:-1 ...	[more]
WFIKKN1	5.682e-9	43.14	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO29819	6.541e-19	60.38	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41696	1.345e-15	53.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26263	1.345e-15	53.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49645	1.913e-14	49.12	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31760	2.163e-13	52.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000012975.2	1.770e-13	58.82	pep primary_assembly:ASM223467v1:12:15740273:15760...	[more]
lrp11	3.715e-13	47.17	low-density lipoprotein receptor-related protein 1...	[more]
ENSORLT00000042019.1	4.755e-13	57.41	pep primary_assembly:ASM223467v1:12:15740119:15780...	[more]
APP	1.667e-12	49.02	amyloid-beta A4 protein [Source:NCBI gene;Acc:1011...	[more]
spint1a	1.932e-12	52.94	kunitz-type protease inhibitor 1 [Source:NCBI gene...	[more]

BLAST of Kunitz-type serine protease inhibitor 6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000013910.1	8.578e-41	100.00	SMESG000013910.1	[more]
SMESG000013915.1	1.037e-35	93.33	SMESG000013915.1	[more]
SMESG000037994.1	7.005e-21	58.33	SMESG000037994.1	[more]
SMESG000038052.1	4.373e-19	54.84	SMESG000038052.1	[more]
SMESG000038055.1	7.276e-18	54.84	SMESG000038055.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence

transcript sequence

>SMED30007141 ID=SMED30007141|Name=Kunitz-type serine protease inhibitor 6|organism=Schmidtea mediterranea sexual|type=transcript|length=336bp
TTTAAACCCTCAAGGTTTTTTTAAATAACAATAATAATAATAATGAATTC
GATAATCATTTTCTCAGTTATATTTGTCGCTACTATTCATTTGGGTGATT
GTAAAGAACCAGAATGCAGTCTTCCTAAAGAAGTCGGTCTGTGCAGAGGA
TATTTCCCAAGGTATTTTTTCAATGAAGAAACGGGAAAATGTGAGAAATT
CATTTATGGTGGATGCCAAGGAAACAAAAATAATTTCTACACTCCAATTG
AATGCAGAGCTCGATGCGAGCAATAATTACTGAATATTTATTTAATAAAA
ATTAAATAATTTTAAAAAAAAAAAAAAAAAATGCGA

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005576	extracellular region

Vocabulary: **biological process**
Term	Definition
GO:0010466	negative regulation of peptidase activity
GO:0006508	proteolysis
GO:0010951	negative regulation of endopeptidase activity

Vocabulary: **molecular function**
Term	Definition
GO:0030414	peptidase inhibitor activity
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0008233	peptidase activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000067	goblet cell
PLANA:0000419	prepharyngeal region
PLANA:0000421	tail
PLANA:0002075	pigment cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036880	Kunitz_BPTI_sf
IPR002223	Kunitz_BPTI
IPR020901	Prtase_inh_Kunz-CS

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PRINTS	PR00759	BASICPTASE	coord: 50..60 score: 63.89 coord: 22..36 score: 35.27 coord: 60..75 score: 47.83
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	SMART	SM00131	KU_2	coord: 23..76 e-value: 4.0E-23 score: 92.8
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PFAM	PF00014	Kunitz_BPTI	coord: 25..76 e-value: 1.8E-19 score: 69.7
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PROSITE	PS50279	BPTI_KUNITZ_2	coord: 25..75 score: 15.437
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	CDD	cd00109	KU	coord: 25..75 e-value: 8.34499E-22 score: 77.6754
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	GENE3D	G3DSA:4.10.410.10		coord: 21..77 e-value: 2.9E-23 score: 83.4
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	SUPERFAMILY	SSF57362	BPTI-like	coord: 19..76
None	No IPR available	PANTHER	PTHR10083:SF322	GEO10309P1	coord: 14..75
None	No IPR available	PANTHER	PTHR10083	KUNITZ-TYPE PROTEASE INHIBITOR-RELATED	coord: 14..75
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..20 score: 0.756
IPR020901	Proteinase inhibitor I2, Kunitz, conserved site	PROSITE	PS00280	BPTI_KUNITZ_1	coord: 53..71

Main menu

Kunitz-type serine protease inhibitor 6

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Owlery

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