Potassium channel subfamily K 8

Overview
NamePotassium channel subfamily K 8
Smed IDSMED30007122
Length (bp)1506
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Potassium channel subfamily K 8 (SMED30007122) t-SNE clustered cells

Violin plots show distribution of expression levels for Potassium channel subfamily K 8 (SMED30007122) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Potassium channel subfamily K 8 (SMED30007122) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Potassium channel subfamily K 8 (SMED30007122) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30007122

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30007122h1SMcG0008043 SmedASXL_010455SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
X1 cellSMED30007122h1SMcG0008043 SmedASXL_010455SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30007122h1SMcG0008043 SmedASXL_010455SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30007122h1SMcG0008043 dd_Smed_v4_17586_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30007122h1SMcG0008043 dd_Smed_v4_17586_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30007122h1SMcG0008043 dd_Smed_v4_17586_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Match: KCNK2 (potassium two pore domain channel subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:6277])

HSP 1 Score: 56.225 bits (134), Expect = 2.399e-8
Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3
Query:  339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800
            FL+V+ Y+I+G  +FK LE+ +EI          S +    IQ+   IS     NS  + EL        + V  IN    P  N S       ++ W++ +S FF  T+ITTIG+GNI+P T+ GKI  +IY++ GIPL    L  VG+ + T F
Sbjct:   51 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 185          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Match: KCNK2 (potassium two pore domain channel subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:6277])

HSP 1 Score: 55.8398 bits (133), Expect = 3.167e-8
Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3
Query:  339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800
            FL+V+ Y+I+G  +FK LE+ +EI          S +    IQ+   IS     NS  + EL        + V  IN    P  N S       ++ W++ +S FF  T+ITTIG+GNI+P T+ GKI  +IY++ GIPL    L  VG+ + T F
Sbjct:   62 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 196          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Match: KCNK2 (potassium two pore domain channel subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:6277])

HSP 1 Score: 56.225 bits (134), Expect = 7.430e-8
Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3
Query:  339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800
            FL+V+ Y+I+G  +FK LE+ +EI          S +    IQ+   IS     NS  + EL        + V  IN    P  N S       ++ W++ +S FF  T+ITTIG+GNI+P T+ GKI  +IY++ GIPL    L  VG+ + T F
Sbjct:   66 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 200          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Match: KCNK2 (potassium two pore domain channel subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:6277])

HSP 1 Score: 55.8398 bits (133), Expect = 8.854e-8
Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3
Query:  339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800
            FL+V+ Y+I+G  +FK LE+ +EI          S +    IQ+   IS     NS  + EL        + V  IN    P  N S       ++ W++ +S FF  T+ITTIG+GNI+P T+ GKI  +IY++ GIPL    L  VG+ + T F
Sbjct:   51 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 185          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Match: KCNK2 (potassium two pore domain channel subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:6277])

HSP 1 Score: 55.8398 bits (133), Expect = 9.928e-8
Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3
Query:  339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800
            FL+V+ Y+I+G  +FK LE+ +EI          S +    IQ+   IS     NS  + EL        + V  IN    P  N S       ++ W++ +S FF  T+ITTIG+GNI+P T+ GKI  +IY++ GIPL    L  VG+ + T F
Sbjct:   62 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 196          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Match: twk-48 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q7YWY7])

HSP 1 Score: 123.635 bits (309), Expect = 5.375e-31
Identity = 108/359 (30.08%), Postives = 174/359 (48.47%), Query Frame = 3
Query:  321 FSHIGTFLMVITYIIMGGFLFKYLEENNEILV---CKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEI--TMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYL------------------------NLCCCRCFISRRVEI---VDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSD 1301
            FSHIG   +V+ Y ++G  +FK +E  +E  +    K    K    +  +  R+  +  S+Q    ++ E++   T+ M S    +  Y+         + G  AQW    +  + +T+ITTIGYGN    T  GK  +M+Y+I GIPLMLLFLTN+G++MA  FRF+Y                         N    R     RV+    VDS       ++E     ++        E    +   + +PI++V+  +  Y+ VG  +F++WE  W+ ++  YF +I+L TIGFGD  P        E   +L++  +Y L G+A+L+MC NL Q+E+ +K RW+ +K    +D D
Sbjct:   25 FSHIGLCALVVGYALLGAVIFKAVEGPHEAEIQELVKSAREKAVDVVWNATFRVNRLD-SKQWKKTVLDEVKRFKTVCMLS---IRKGYDGK-------EYGKQAQWTFTGAFLYSLTVITTIGYGNTAAKTYIGKTLTMLYAIIGIPLMLLFLTNIGDVMAKIFRFLYAQSIRLKFRLILWHKKRKAAKIRRANSLVSRLTRGHRVKADSSVDSFGLGAGADVEDLLTARVEMEQLEVRETAAAQLESMTVPISLVVFTMLGYLGVGTTIFKVWEG-WTFLESFYFCFISLTTIGFGDKFPSTSVSNTDEAQEKLVITSIYLLFGMALLAMCFNLAQEEVQNKTRWIADKFRSKEDDD 371          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Match: twk-39 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:A1EHR5])

HSP 1 Score: 93.9745 bits (232), Expect = 3.875e-20
Identity = 47/111 (42.34%), Postives = 69/111 (62.16%), Query Frame = 3
Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADDVEPFSYSTS 1358
            GA LF  WE  W+  DG Y+ +ITL+TIGFGD VPG+   E ++   +L+V  +Y L G+A+++MC  L+QD++  K RWLG K+G++     L +E     +  F YS S
Sbjct:  508 GAWLFSWWEN-WNGFDGAYYCFITLSTIGFGDIVPGQALDEGSQE--KLVVCALYLLFGMALIAMCFKLMQDDVVQKARWLGQKIGILARPFELSREIAKHAIFLFGYSVS 615          

HSP 2 Score: 73.9442 bits (180), Expect = 1.045e-13
Identity = 57/188 (30.32%), Postives = 96/188 (51.06%), Query Frame = 3
Query:  291 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQR------IMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRC 836
            T ++++     +H+G   +V  Y + G F+F+ +E   E L  + K    S K+ + I R      ++  +  + E+   + E E+ +      V  +N+E         +     QW    ++ + +T+ TTIGYG+I P TD G++ +++YSI GIPLMLL L N+ E +A  F +IY  LCC  C
Sbjct:   14 TFVKSATIFTITHVGLCFLVALYAVAGAFMFQAVEYPYE-LGLQGKVKNASLKVVDDIYRFINRKNVIEETAVKNESQWALKEFEMLL------VHAMNFE---GYDEHDEERPTFQWTFSGALLYSITVFTTIGYGHICPKTDTGRLLTILYSILGIPLMLLCLANIAETLAQVFTYIYFKLCCAYC 191          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Match: twk-39 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:A1EHR5])

HSP 1 Score: 91.2781 bits (225), Expect = 3.060e-19
Identity = 41/88 (46.59%), Postives = 61/88 (69.32%), Query Frame = 3
Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLI 1289
            GA LF  WE  W+  DG Y+ +ITL+TIGFGD VPG+   E ++   +L+V  +Y L G+A+++MC  L+QD++  K RWLG K+G++
Sbjct:  508 GAWLFSWWEN-WNGFDGAYYCFITLSTIGFGDIVPGQALDEGSQE--KLVVCALYLLFGMALIAMCFKLMQDDVVQKARWLGQKIGIL 592          

HSP 2 Score: 74.3294 bits (181), Expect = 8.328e-14
Identity = 57/188 (30.32%), Postives = 96/188 (51.06%), Query Frame = 3
Query:  291 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQR------IMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRC 836
            T ++++     +H+G   +V  Y + G F+F+ +E   E L  + K    S K+ + I R      ++  +  + E+   + E E+ +      V  +N+E         +     QW    ++ + +T+ TTIGYG+I P TD G++ +++YSI GIPLMLL L N+ E +A  F +IY  LCC  C
Sbjct:   14 TFVKSATIFTITHVGLCFLVALYAVAGAFMFQAVEYPYE-LGLQGKVKNASLKVVDDIYRFINRKNVIEETAVKNESQWALKEFEMLL------VHAMNFE---GYDEHDEERPTFQWTFSGALLYSITVFTTIGYGHICPKTDTGRLLTILYSILGIPLMLLCLANIAETLAQVFTYIYFKLCCAYC 191          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Match: twk-28 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q22940])

HSP 1 Score: 90.5077 bits (223), Expect = 4.461e-19
Identity = 92/340 (27.06%), Postives = 168/340 (49.41%), Query Frame = 3
Query:  312 KVAFSHIGTFLMVITYIIMGGFLFKYLEENNE----------ILVCKEKYNKYSTKLNE-SIQRIMAISTSRQENSQIMSEL--EITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEI----EDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKL 1280
            K    H+G  +++  Y+I G FLF+YLE   E          IL  ++++  +   + + S  RI     SR+  + I  E   ++   MF    ++  +  +K+     +   +  W   NS+FF  T+ITTIGYGN+ P+T  G++  +I+++ GIPL+L+ + ++G+ ++ F  ++Y +    +  + R+ + + S    +  +           G+   ++I    ED     + IP+ +VL+VL  Y  +G  LF+ WE      +  YF +IT+AT+GFGD VP +  +        +     Y + GL++ +MC++L   E   K  +LG K+
Sbjct:   57 KRILPHVGLVILLFLYLIAGAFLFRYLEAPKELETRNHELTTILGLRDEFQDHIWNITQDSDNRI-----SREAFNAINQEYFEQLVKNMFQ--AYRNQFITAKHLLNKTREDEVL-WTFPNSMFFAATVITTIGYGNLVPITVTGRVACIIFALLGIPLLLVTIADIGKFLSEFLSYLYRSYRGFKRKLRRQSKKITSQYRSQSQSRSSSVMGSSKAGSMNLHDIDSDSEDSAGDELRIPVFMVLLVLLAYTAIGGFLFQSWEH-LEYFEAFYFCFITMATVGFGDIVPNEQVY--------VFFTMAYIIFGLSLATMCIDLAGTEYIRKIHYLGTKM 379          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Match: twk-40 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q9XU07])

HSP 1 Score: 86.2705 bits (212), Expect = 7.191e-18
Identity = 93/334 (27.84%), Postives = 174/334 (52.10%), Query Frame = 3
Query:  300 QTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIG----QPGNLAQ---WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKL 1280
            +T  ++  +H+   ++ + Y+  G FLF  LE+ NE+ V      +++    + I+ +  +  S      ++ +L +    +  +V +I +E + +   IG    +PG   +   W    ++FF  T++TTIGYGN+TP+T  GK+  ++Y++FG+PL+L+ + ++G+ ++     +Y      R   S++   V S+++DK  N EG            D  ++  EN ++ IPI +++ +L  YI  GA +  +WE  W    G YFS+IT+ T+GFGD VP K  +         I+   Y ++GL+I +MC++L+  +   K  + G  +
Sbjct:   48 KTYARIILAHVSLIVLSVVYVGFGAFLFYQLEQPNEVEVRARNIERFNIHKRQMIEHLWEMRES-GIGQHVVEDLAVK---YVDNVTRILFE-AFDTHCIGAKHLRPGGEDEDYNWTYMTALFFTTTLLTTIGYGNLTPVTGRGKLLCILYALFGVPLILITVADIGKFLSENIVQLYTWYRKLREKCSKQKYSVISSKDDK--NKEG------------DLNLDHLEN-YISIPIFLIVAILLSYITFGAVVLSMWEG-WDFFSGFYFSFITMTTVGFGDIVPLKREY--------YILDLCYIIIGLSITTMCIDLVGIQYIRKMHYFGRAI 352          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Match: CG9194 (gene:FBgn0035192 transcript:FBtr0072651)

HSP 1 Score: 92.0485 bits (227), Expect = 2.370e-19
Identity = 68/208 (32.69%), Postives = 112/208 (53.85%), Query Frame = 3
Query:  324 SHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGN----LAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRC-FISRRVEIVDSTEND--KKLNIEGQPPPKINE 926
            SH+   L+V++Y + G +LF++LE  +E+ V ++  N     L E+I  +   +   +E S  M+ +   +  F K +              G  G+     +QW    S+F+ + +ITTIGYG+I+P TDWGK+ ++ Y+I GIPLML+ L+N+G++MAT FRF+Y  +CC  C   ++R     S +     + +   QPPP    
Sbjct:   40 SHVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQN-LRVNLTENIWLLSDDAVVLRE-SDWMANVSKHLANFEKQILTA-------IKADGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIGDVMATSFRFLYWRICCYVCTRTAKRPRNARSRQRSMRSQRHARSQPPPSFRR 238          

HSP 2 Score: 77.7962 bits (190), Expect = 7.935e-15
Identity = 38/88 (43.18%), Postives = 54/88 (61.36%), Query Frame = 3
Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLI 1289
            GA LF  WE  WS +D  YF +ITL TIGFGDFVP K    K E+   +    +Y L G+A+L+M  NL+Q+E  +  + +  +LG++
Sbjct:  635 GAVLFAYWEN-WSFLDSAYFCFITLTTIGFGDFVPAKG--VKDESEQSIAYCSLYLLFGIALLAMSFNLVQEEFIANVKEVARRLGIL 719          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Match: CG10864 (gene:FBgn0038621 transcript:FBtr0083654)

HSP 1 Score: 83.9593 bits (206), Expect = 3.120e-17
Identity = 93/353 (26.35%), Postives = 159/353 (45.04%), Query Frame = 3
Query:  294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQ--WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPG---------------------KDGFE-------KAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262
            C +  +    + +G   +++ Y I G F F ++E      V +   +    + N S Q++ +I+    E   I+     T    + DV +            G  G   +  W+   ++ FC+++IT IGYGN+ P T WGK  ++IY+ FGIPL +L+  N+G ++A  F+F+Y +L  C      R++ +D+ E    +  +    P                        T  L V+F Y++ G  +F  WE+ WS+++  YF   +L  IGFGDFVPG                      D  E        A+  ++L +  +Y LLG+ +++MC NL+++E+  K R
Sbjct:   39 CCRNFVTFMCTQVGVGALIVIYAICGAFAFMHIERQ---FVDETAGHVMELRQNCS-QQLWSIT----EQHNIIDRRRWTEA--TNDVLREYQSQIAGVVKHGYVGRSPEQIWSFPAALMFCLSVITMIGYGNMVPRTPWGKGFTVIYATFGIPLYILYFLNMGRVLARSFKFLYRSLHDC-TQEHPRLDRMDALEGGVGMTRKKVIVPS-----------------------TACLWVIFFYVLTGTVMFANWEK-WSLLNSFYFCMTSLCKIGFGDFVPGASLTTSADVNAATQKLQEDISADPAELAQLQSVAADQHSKLAINFVYMLLGMGLVAMCRNLMREEVRLKAR 356          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Match: CG34396 (gene:FBgn0085425 transcript:FBtr0112645)

HSP 1 Score: 76.2554 bits (186), Expect = 2.693e-14
Identity = 68/263 (25.86%), Postives = 129/263 (49.05%), Query Frame = 3
Query:  606 PGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMA-------TFFRFIYLNLCCCRCFISRRVEIV---------------------DSTENDKKLNIEGQPPPKINEGNHPD---------YEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLG 1283
            PG  + WN  N   FC T+ITTIGYG+ITP T  G+  +++Y+I GIP+ L+ L ++G++          + R +Y    C R    +++                         + END++   + +    +   +HP+         +E++D+ N+ V +   +++  + +    G+  F + E  W+ +D  Y+ +I+++TIGFGD VP    +        ++V  +Y + GLA+ SM +N++Q +++  F+    K+G
Sbjct:  609 PGQKS-WNFVNCFIFCWTVITTIGYGHITPKTGMGRSLTIVYAIIGIPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSMFFSNSAPENDEESQADAEAARSVG-TSHPETPTSPYPETFEVDDEFNLPVSVASLLLITYILL----GSFGFLMMEPSWTPLDAFYYVFISMSTIGFGDLVPSNPFY--------VMVSMIYLMFGLALTSMFINVVQIKLSDHFKMASAKVG 857          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Match: CG34396 (gene:FBgn0085425 transcript:FBtr0112644)

HSP 1 Score: 73.1738 bits (178), Expect = 2.058e-13
Identity = 63/261 (24.14%), Postives = 128/261 (49.04%), Query Frame = 3
Query:  612 NLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMA-------TFFRFIYLNLCCCRCFISRRVEIV---------------------DSTENDKKLNIEGQPPPKINEGNHPD---------YEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLG 1283
            N   W+ ++++ +  TI TTIGYG+ITP T  G+  +++Y+I GIP+ L+ L ++G++          + R +Y    C R    +++                         + END++   + +    +   +HP+         +E++D+ N+ V +   +++  + +    G+  F + E  W+ +D  Y+ +I+++TIGFGD VP    +        ++V  +Y + GLA+ SM +N++Q +++  F+    K+G
Sbjct:  199 NTDPWSFWDAMVYSATIYTTIGYGHITPKTGMGRSLTIVYAIIGIPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSMFFSNSAPENDEESQADAEAARSVGT-SHPETPTSPYPETFEVDDEFNLPVSVASLLLITYILL----GSFGFLMMEPSWTPLDAFYYVFISMSTIGFGDLVPSNPFY--------VMVSMIYLMFGLALTSMFINVVQIKLSDHFKMASAKVG 446          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Match: sand (gene:FBgn0033257 transcript:FBtr0088780)

HSP 1 Score: 71.2478 bits (173), Expect = 4.632e-13
Identity = 33/81 (40.74%), Postives = 53/81 (65.43%), Query Frame = 3
Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGF--EKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262
            GA LF  WE +W+ +DG+YF  I+L++IGFGD VPG      ++ +     I+  +Y LLG+A+++MC NL+Q+++    R
Sbjct:  301 GALLFGRWE-DWNYLDGSYFCLISLSSIGFGDLVPGDRVITADRDKVEVSFILCAIYLLLGMAVIAMCFNLMQEQVVHNIR 380          

HSP 2 Score: 70.0922 bits (170), Expect = 1.287e-12
Identity = 55/178 (30.90%), Postives = 100/178 (56.18%), Query Frame = 3
Query:  321 FSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFK-------INYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCR 833
            FS++G  L+V  YII G F+F+ +E             +Y    +E   R +A + S +  S+I       ++ F    ++       ++Y+ +     +  P ++ QW+   +  + +T+ITTIGYGNITP ++ GK+ +++Y+I G+PL LL+L+N+G+++A  F++IY  +C CR
Sbjct:   31 FSNVGIILLVTFYIIGGAFIFQSIE-----------IFEYERLKSEKPHRFIARNFSGECLSRIWELTAENISFFDHHAYRRRVNDVLLDYQRAIVKKQLKGP-DVEQWSFSGAFLYSLTVITTIGYGNITPHSECGKLVTILYAIIGMPLFLLYLSNIGDVLAKSFKWIYSKVCLCR 196          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Match: kcnk15 (potassium channel, subfamily K, member 15 [Source:ZFIN;Acc:ZDB-GENE-080220-30])

HSP 1 Score: 66.2402 bits (160), Expect = 2.067e-11
Identity = 64/205 (31.22%), Postives = 94/205 (45.85%), Query Frame = 3
Query:  621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235
            QW    S +F +T+ITTIGYG+  P TD GK+  M+Y+  GIPL L+   ++GE M T  RF+   +   R    +R EI  ST+N   + +                                  +     + VGA  F  +E  W+     Y+ +ITL TIGFGDFV  +   +  E    ++   +Y LLGL ++   LNL+
Sbjct:   77 QWRFAGSFYFAITVITTIGYGHAAPGTDAGKLFCMLYAGLGIPLTLVMFQSLGERMNTGVRFLLSRMK--RALGLQRTEI--STQNMVLVGV----------------------------------LSCLGTLCVGAAAFSHFE-SWTFFHAYYYCFITLTTIGFGDFVALQKKEDLQENQPYVLFSFIYILLGLTVIGAFLNLV 242          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Match: kcnk15 (potassium channel, subfamily K, member 15 [Source:ZFIN;Acc:ZDB-GENE-080220-30])

HSP 1 Score: 65.4698 bits (158), Expect = 2.670e-11
Identity = 64/205 (31.22%), Postives = 94/205 (45.85%), Query Frame = 3
Query:  621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235
            QW    S +F +T+ITTIGYG+  P TD GK+  M+Y+  GIPL L+   ++GE M T  RF+   +   R    +R EI  ST+N   + +                                  +     + VGA  F  +E  W+     Y+ +ITL TIGFGDFV  +   +  E    ++   +Y LLGL ++   LNL+
Sbjct:   77 QWRFAGSFYFAITVITTIGYGHAAPGTDAGKLFCMLYAGLGIPLTLVMFQSLGERMNTGVRFLLSRMK--RALGLQRTEI--STQNMVLVGV----------------------------------LSCLGTLCVGAAAFSHFE-SWTFFHAYYYCFITLTTIGFGDFVALQKKEDLQENQPYVLFSFIYILLGLTVIGAFLNLV 242          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Match: kcnk9 (potassium channel, subfamily K, member 9 [Source:ZFIN;Acc:ZDB-GENE-070705-260])

HSP 1 Score: 64.3142 bits (155), Expect = 1.411e-10
Identity = 63/205 (30.73%), Postives = 89/205 (43.41%), Query Frame = 3
Query:  621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235
            QW    S +F +T+ITTIGYG+  P TD GK   M Y++ GIPL L+   ++GE M TF +  YL     +C   R  E+  S EN   +                                          + +GA  F  +E +WS     Y+ +ITL TIGFGDFV  +      +    +    MY L+GL ++   LNL+
Sbjct:  168 QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVK--YLLKRIKKCCGMRITEV--SMENMVTVGF----------------------------------FSCMGTLCIGAAAFSQYE-DWSFFQSYYYCFITLTTIGFGDFVALQKNKALQKKPLYVAFSFMYILVGLTVIGAFLNLV 333          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Match: kcnk3a (potassium channel, subfamily K, member 3a [Source:ZFIN;Acc:ZDB-GENE-040724-171])

HSP 1 Score: 63.1586 bits (152), Expect = 2.419e-10
Identity = 61/205 (29.76%), Postives = 90/205 (43.90%), Query Frame = 3
Query:  621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235
            QW    S +F +T+ITTIGYG+  P TD GK+  M Y++ GIPL L+   ++GE + TF +++   L   +C   R  E+  S  N   + +                                  I     + VGA  F  +E +WS     Y+ +ITL TIGFGD+V  +           +    MY L GL ++   LNL+
Sbjct:   77 QWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTFVKYLLHRL--KKCLGLRHTEV--SMANMVCIGL----------------------------------ISCMSTLCVGAAAFSRYE-DWSFFHAYYYCFITLTTIGFGDYVALQKDNALQTNPQYVAFSFMYILTGLTVIGAFLNLV 242          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Match: kcnk18 (potassium channel, subfamily K, member 18 [Source:ZFIN;Acc:ZDB-GENE-100405-2])

HSP 1 Score: 60.077 bits (144), Expect = 2.405e-9
Identity = 47/168 (27.98%), Postives = 84/168 (50.00%), Query Frame = 3
Query:  321 FSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFK-INYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNL 821
            F H+   L ++ Y ++G  +F+ +E  N            S ++   +Q++M I  +  + S+     +  +   +KD+     YE  ++            W  + S+FFC T+ TT+GYG I PLT  GK+  ++Y++ GIPLMLL +++VG+++A      Y  L
Sbjct:   21 FPHVFLILSLVLYAVLGALVFRAIEYKNP--------RNESEEILSIVQKVMEIVQNHTDTSE-----QKHLINKAKDILDDYCYEKERDHG----------WTFFASLFFCCTVFTTVGYGRIYPLTSKGKVACVLYAMVGIPLMLLVISDVGDLLAVLLSKAYTRL 165          

HSP 2 Score: 53.9138 bits (128), Expect = 2.331e-7
Identity = 27/76 (35.53%), Postives = 41/76 (53.95%), Query Frame = 3
Query: 1035 LFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262
            + + WE++    D  YF++ITL TIGFGD VP    F         +V  ++ + G+AI+SM   L Q +I   +R
Sbjct:  304 ILKCWEKQMDHSDAFYFTFITLTTIGFGDIVPEHPKF--------FMVTFLFIITGMAIMSMAFKLGQSQIVCFYR 371          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Match: pole4 (polymerase (DNA-directed), epsilon 4, accessory subunit [Source:Xenbase;Acc:XB-GENE-5722002])

HSP 1 Score: 74.3294 bits (181), Expect = 1.073e-13
Identity = 66/205 (32.20%), Postives = 94/205 (45.85%), Query Frame = 3
Query:  621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235
            QW    S +F +T+ITTIGYG+  P TD GK+  M Y++ GIPL L+   ++GE M TF RF+   L   RCF  R+ E+  S EN                                   + V  +     + +GA  F  +E  W+     Y+ +ITL TIGFGDFV  +      +    +    MY L+GL ++   LNL+
Sbjct:   89 QWKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFLLKKL--KRCFRLRKTEV--SMEN----------------------------------MVLVGFLSCIGTLGIGAAAFSYFEG-WTFFHSYYYCFITLTTIGFGDFVALQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLV 254          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Match: pole4 (polymerase (DNA-directed), epsilon 4, accessory subunit [Source:Xenbase;Acc:XB-GENE-5722002])

HSP 1 Score: 73.559 bits (179), Expect = 2.133e-13
Identity = 69/215 (32.09%), Postives = 99/215 (46.05%), Query Frame = 3
Query:  591 STIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235
            +TIG+     QW    S +F +T+ITTIGYG+  P TD GK+  M Y++ GIPL L+   ++GE M TF RF+   L   RCF  R+ E+  S EN                                   + V  +     + +GA  F  +E  W+     Y+ +ITL TIGFGDFV  +      +    +    MY L+GL ++   LNL+
Sbjct:   93 TTIGK-----QWKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFLLKKL--KRCFRLRKTEV--SMEN----------------------------------MVLVGFLSCIGTLGIGAAAFSYFEG-WTFFHSYYYCFITLTTIGFGDFVALQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLV 263          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Match: pole4 (polymerase (DNA-directed), epsilon 4, accessory subunit [Source:Xenbase;Acc:XB-GENE-5722002])

HSP 1 Score: 73.1738 bits (178), Expect = 2.628e-13
Identity = 66/205 (32.20%), Postives = 94/205 (45.85%), Query Frame = 3
Query:  621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235
            QW    S +F +T+ITTIGYG+  P TD GK+  M Y++ GIPL L+   ++GE M TF RF+   L   RCF  R+ E+  S EN                                   + V  +     + +GA  F  +E  W+     Y+ +ITL TIGFGDFV  +      +    +    MY L+GL ++   LNL+
Sbjct:   78 QWKFTGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFLLKKL--KRCFRLRKTEV--SMEN----------------------------------MVLVGFLSCIGTLGIGAAAFSYFEG-WTFFHSYYYCFITLTTIGFGDFVALQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLV 243          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Match: KCNK18 (potassium two pore domain channel subfamily K member 18 [Source:HGNC Symbol;Acc:HGNC:19439])

HSP 1 Score: 60.8474 bits (146), Expect = 1.984e-9
Identity = 25/79 (31.65%), Postives = 44/79 (55.70%), Query Frame = 3
Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262
            GAC+  +WE +W+ +D  YF ++TL TIGFGD +P    +         ++   Y ++G+ I+ M   L Q+ + S ++
Sbjct:  268 GACILPLWEDDWTTIDAFYFCFVTLTTIGFGDIIPKHPNY--------FLLLSAYTVVGMVIVCMAFKLGQNRLVSFYK 338          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Match: prss1.2 (protease, serine, 1 (trypsin 1), gene 2 [Source:Xenbase;Acc:XB-GENE-6083469])

HSP 1 Score: 50.447 bits (119), Expect = 3.514e-6
Identity = 25/71 (35.21%), Postives = 43/71 (60.56%), Query Frame = 3
Query: 1029 ACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQD 1241
            A +F   E+ W  VD  YF +I+L+TIG GD+VPG+   ++     +L+V   Y L+GL  + + + +I++
Sbjct:  187 AIVFNAIEENWGYVDALYFCFISLSTIGLGDYVPGERNEQRLPVLYKLLV-ICYLLIGLVAVFLVVEVIKN 256          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Match: Kcnk6 (potassium inwardly-rectifying channel, subfamily K, member 6 [Source:MGI Symbol;Acc:MGI:1891291])

HSP 1 Score: 62.003 bits (149), Expect = 4.383e-10
Identity = 64/258 (24.81%), Postives = 119/258 (46.12%), Query Frame = 3
Query:  624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADDVEPFSYSTSQPQENQMKIMQTN 1397
            W+  +++FF  T++TT+GYG  TPLTD GK  S+++++ G+P+ +L LT   +                      R+ ++ +      L++    PP+     H                + ++++++ I+ +V A +F   E+ WS +D  YF +I+L+TIG GD+VPG+   +      +++V   Y  LGL  + + L          FR + +  GL          EL    +P   S SQ +++Q+ ++   
Sbjct:   91 WDFASALFFASTLVTTVGYGYTTPLTDAGKAFSIVFALLGVPITMLLLTASAQ----------------------RLSLLLTHAPLSWLSLHWGWPPQRAARWH---------------LVALLMVIVAIFFLVPAAVFAYLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTA-YLFLGLVAMVLVLQ--------TFRRVSDLHGL---------TELILLPDPDPASLSQDEDDQVAVLDAR 293          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Match: Kcnk18 (potassium channel, subfamily K, member 18 [Source:MGI Symbol;Acc:MGI:2685627])

HSP 1 Score: 55.4546 bits (132), Expect = 9.523e-8
Identity = 29/63 (46.03%), Postives = 46/63 (73.02%), Query Frame = 3
Query:  624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIY 812
            W+  +++FFC T+ +T+GYG++ P+T  GK   M+Y++FGIPLM L LT++G+I+AT     Y
Sbjct:  112 WSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLVLTDIGDILATILSRAY 174          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Match: Kcnk2 (potassium channel, subfamily K, member 2 [Source:MGI Symbol;Acc:MGI:109366])

HSP 1 Score: 53.9138 bits (128), Expect = 9.768e-8
Identity = 55/156 (35.26%), Postives = 80/156 (51.28%), Query Frame = 3
Query:  339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800
            FL+V+ Y+I+G  +FK LE+  EI          S +    IQ+   I+     NS  + EL        + V  IN    P  N S       ++ W++ +S FF  T+ITTIG+GNI+P T+ GKI  +IY++ GIPL    L  VG+ + T F
Sbjct:   62 FLVVVLYLIIGATVFKALEQPQEI----------SQRTTIVIQKQTFIAQHACVNSTELDEL------IQQIVAAINAGIIPLGNSSN-----QVSHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 196          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Match: Kcnk2 (potassium channel, subfamily K, member 2 [Source:MGI Symbol;Acc:MGI:109366])

HSP 1 Score: 54.6842 bits (130), Expect = 1.746e-7
Identity = 55/156 (35.26%), Postives = 80/156 (51.28%), Query Frame = 3
Query:  339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800
            FL+V+ Y+I+G  +FK LE+  EI          S +    IQ+   I+     NS  + EL        + V  IN    P  N S       ++ W++ +S FF  T+ITTIG+GNI+P T+ GKI  +IY++ GIPL    L  VG+ + T F
Sbjct:   66 FLVVVLYLIIGATVFKALEQPQEI----------SQRTTIVIQKQTFIAQHACVNSTELDEL------IQQIVAAINAGIIPLGNSSN-----QVSHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 200          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Match: Kcnk2 (potassium channel, subfamily K, member 2 [Source:MGI Symbol;Acc:MGI:109366])

HSP 1 Score: 54.299 bits (129), Expect = 1.957e-7
Identity = 55/156 (35.26%), Postives = 80/156 (51.28%), Query Frame = 3
Query:  339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800
            FL+V+ Y+I+G  +FK LE+  EI          S +    IQ+   I+     NS  + EL        + V  IN    P  N S       ++ W++ +S FF  T+ITTIG+GNI+P T+ GKI  +IY++ GIPL    L  VG+ + T F
Sbjct:   54 FLVVVLYLIIGATVFKALEQPQEI----------SQRTTIVIQKQTFIAQHACVNSTELDEL------IQQIVAAINAGIIPLGNSSN-----QVSHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 188          
BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Match: sp|P34410|TWK7_CAEEL (TWiK family of potassium channels protein 7 OS=Caenorhabditis elegans OX=6239 GN=twk-7 PE=3 SV=3)

HSP 1 Score: 84.7297 bits (208), Expect = 4.701e-16
Identity = 92/338 (27.22%), Postives = 165/338 (48.82%), Query Frame = 3
Query:  291 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAIS----TSRQE----NSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKL 1280
            T ++   K+   H+   L+  TY ++G  +F  +E+ +E ++ +++     T+ NE +  ++ ++    T R E      + M  +   + +  +  F  + E  KN +T         W   +SIFF VT++TTIGYGN  P+T+ G+I  +++S+ GIPL L+ + ++G+ ++    ++Y N    +  I  R          +K   E       + G   D  IE+       IP  +VL +L +Y   G  L    E  WS     Y+S+IT+ T+GFGD +P +DG+        + +  +Y +LGLAI +MC++L+  +   K  + G K+
Sbjct:  153 TGIRKFAKLVLPHVALVLLTCTYTVIGALIFYSVEQPHEQMMKEQQLKLIYTRQNEFVDDLIRLAAGNETKRYEWESLAERHMHNMSDQLFVAFEKYFLTSNEVKKNAAT-------ETWTFSSSIFFAVTVVTTIGYGNPVPVTNIGRIWCILFSLLGIPLTLVTIADLGKFLSEHLVWLYGNYLKLKYLILSR---------HRKERREHVCEHCHSHGMGHDMNIEEKR-----IPAFLVLAILIVYTAFGGVLMSKLEP-WSFFTSFYWSFITMTTVGFGDLMPRRDGY--------MYIILLYIILGLAITTMCIDLVGVQYIRKIHYFGRKI 460          
BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Match: sp|Q18120|TWK18_CAEEL (TWiK family of potassium channels protein 18 OS=Caenorhabditis elegans OX=6239 GN=twk-18 PE=1 SV=2)

HSP 1 Score: 76.2554 bits (186), Expect = 1.785e-13
Identity = 81/327 (24.77%), Postives = 153/327 (46.79%), Query Frame = 3
Query:  291 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSE----LEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRV--EIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIAS 1253
            + + T+ +  F  +   ++++ Y ++G ++F  +E  NE  +  E+  +    +  ++ +I  +   RQ       E        +T F + +  +  +  K+            W    SIF+C+T+ TTIGYGNI P T WG+  +++Y+  GIPL +L L  +G + A   + ++         +S+ +  +I ++ +N ++      P  +  E N  D          +  PI+ +L++  I++I  A LF   E EW      YF+ I+  TIGFGD +P    F        + + G+  L+GL+++S  + LIQ +I +
Sbjct:    9 STILTTFQKTFKGLLPLIILVAYTLLGAWIFWMIEGENEREMLIEQQKERDELIRRTVYKINQLQIKRQRRLMTAEEEYNRTAKVLTTFQETLGIVPADMDKDI----------HWTFLGSIFYCMTVYTTIGYGNIVPGTGWGRFATILYAFIGIPLTVLSLYCLGSLFAKGCKMLWRFFLKSTRVVSKDLSNKISEAADNIEEGTTAITPSAEKTENNDDD---------LLSFPISGLLLITVIWVIFCAVLFTFLE-EWDFGTSLYFTLISFTTIGFGDILPSDYDF--------MPIVGVLLLIGLSLVSTVMTLIQQQIEA 307          
BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Match: sp|O95069|KCNK2_HUMAN (Potassium channel subfamily K member 2 OS=Homo sapiens OX=9606 GN=KCNK2 PE=1 SV=2)

HSP 1 Score: 56.225 bits (134), Expect = 3.568e-7
Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3
Query:  339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800
            FL+V+ Y+I+G  +FK LE+ +EI          S +    IQ+   IS     NS  + EL        + V  IN    P  N S       ++ W++ +S FF  T+ITTIG+GNI+P T+ GKI  +IY++ GIPL    L  VG+ + T F
Sbjct:   66 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 200          
BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Match: sp|Q7Z418|KCNKI_HUMAN (Potassium channel subfamily K member 18 OS=Homo sapiens OX=9606 GN=KCNK18 PE=1 SV=1)

HSP 1 Score: 55.4546 bits (132), Expect = 6.415e-7
Identity = 47/167 (28.14%), Postives = 82/167 (49.10%), Query Frame = 3
Query:  294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMAT 794
            C   ++   F  +     ++TY ++G  +F  +E + ++LV  +  +    K  E + RI+  S +  E+ +   +L+  +       F                     W+  +S+FFC T+ +T+GYG I P+T  GK   M+Y++FGIPLM L LT+ G+I+AT
Sbjct:   12 CCPEALGKLFPGLCFLCFLVTYALVGAVVFSAIE-DGQVLVAAD--DGEFEKFLEELCRILNCSETVVEDRK--QDLQGHLQKVKPQWF----------------NRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILAT 157          
BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Match: sp|Q6VV64|KCNKI_MOUSE (Potassium channel subfamily K member 18 OS=Mus musculus OX=10090 GN=Kcnk18 PE=1 SV=1)

HSP 1 Score: 55.4546 bits (132), Expect = 6.661e-7
Identity = 29/63 (46.03%), Postives = 46/63 (73.02%), Query Frame = 3
Query:  624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIY 812
            W+  +++FFC T+ +T+GYG++ P+T  GK   M+Y++FGIPLM L LT++G+I+AT     Y
Sbjct:  112 WSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLVLTDIGDILATILSRAY 174          
BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Match: A0A1I8IZX5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 293.508 bits (750), Expect = 2.218e-87
Identity = 170/339 (50.15%), Postives = 232/339 (68.44%), Query Frame = 3
Query:  315 VAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAIS---TSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKK--LNIE-------GQPPPKINE--GNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGL 1286
            +  SH+GT  +VI Y+IMGGFLF YLEE NE   C   Y+KY  K NE+  R+  I+    S    S I+S+LE+    F+KD++ ++ +P+KNCSTIG   N A W + N+I+FC TI+TTIGYG+I+P T WG+I  MIY+I GIPLMLLFLT +GE  A  FR  YLN+CCC+CF+ RR     + E  +    N+E        QPPPK+        D   +D ++  V IPITV +++L +YI+VGA +F  WE++W++V+GTYFS+ITL+TIGFGD+VPG++G F+      EL+VG +YCL GLA+LSMC+NLIQDEI +K RW+GNK+G+
Sbjct:  323 IMLSHLGTLTLVIIYLIMGGFLFNYLEETNEKSACSIAYSKYEAKRNEATDRVYNIAQGANSSLSKSAILSQLEV----FAKDIYTLSVDPTKNCSTIGTVDNPANWVLANAIYFCTTIVTTIGYGHISPTTQWGQIICMIYAILGIPLMLLFLTKIGEPTAMLFRSFYLNICCCKCFVKRRHPAQSAGEQQQTEWRNVEDGGDGQAKQPPPKVGTVLVVEEDDNDDDFDDEVVNIPITVTIMLLILYILVGAAVFTAWEKDWTLVEGTYFSFITLSTIGFGDYVPGRNGPFDDVSVIMELLVGAIYCLFGLAMLSMCMNLIQDEITAKLRWIGNKMGI 657          

HSP 2 Score: 144.821 bits (364), Expect = 3.309e-33
Identity = 84/187 (44.92%), Postives = 121/187 (64.71%), Query Frame = 3
Query:  774 VGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINE--GNHPDYEIED------------DENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLI 1289
            +GE  A  F+  YLN+CCC+CFI R+     + E   +     Q      +  G  P  +++D            +E   V IPI+V +++L +YI++GA +FRIWE+ W++++GTYFS+ITL+TIGFGD+VPGKDG F      TEL+VG +YC  GL +LSMC+NLIQDEI++KF W+G KLG++
Sbjct:  118 IGEPTAMLFKAFYLNICCCKCFIKRKCPEEKAVEESIREQQRQQSSWTTADESGKMPPAKVKDLVVVEEDDEEDDEEEDIVNIPISVTILLLILYILLGAAVFRIWEK-WTLIEGTYFSFITLSTIGFGDYVPGKDGPFNSMTVITELLVGALYCFFGLTVLSMCINLIQDEISAKFHWIGLKLGMV 303          
BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Match: A0A1I8HPD6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 293.893 bits (751), Expect = 3.710e-87
Identity = 170/339 (50.15%), Postives = 232/339 (68.44%), Query Frame = 3
Query:  315 VAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAIS---TSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKK--LNIE-------GQPPPKINE--GNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGL 1286
            +  SH+GT  +VI Y+IMGGFLF YLEE NE   C   Y+KY  K NE+  R+  I+    S    S I+S+LE+    F+KD++ ++ +P+KNCSTIG   N A W + N+I+FC TI+TTIGYG+I+P T WG+I  MIY+I GIPLMLLFLT +GE  A  FR  YLN+CCC+CF+ RR     + E  +    N+E        QPPPK+        D   +D ++  V IPITV +++L +YI+VGA +F  WE++W++V+GTYFS+ITL+TIGFGD+VPG++G F+      EL+VG +YCL GLA+LSMC+NLIQDEI +K RW+GNK+G+
Sbjct:  357 IMLSHLGTLTLVIIYLIMGGFLFNYLEETNEKSACSIAYSKYEAKRNEATDRVYNIAQGANSSLSKSAILSQLEV----FAKDIYTLSVDPTKNCSTIGTVDNPANWVLANAIYFCTTIVTTIGYGHISPTTQWGQIICMIYAILGIPLMLLFLTKIGEPTAMLFRSFYLNICCCKCFVKRRHPAQSAGEQQQTEWRNVEDGGDGQAKQPPPKVGTVLVVEEDDNDDDFDDEVVNIPITVTIMLLILYILVGAAVFTAWEKDWTLVEGTYFSFITLSTIGFGDYVPGRNGPFDDVSVIMELLVGAIYCLFGLAMLSMCMNLIQDEITAKLRWIGNKMGI 691          

HSP 2 Score: 146.747 bits (369), Expect = 8.718e-34
Identity = 86/201 (42.79%), Postives = 126/201 (62.69%), Query Frame = 3
Query:  774 VGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINE--GNHPDYEIED------------DENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADD 1331
            +GE  A  F+  YLN+CCC+CFI R+     + E   +     Q      +  G  P  +++D            +E   V IPI+V +++L +YI++GA +FRIWE+ W++++GTYFS+ITL+TIGFGD+VPGKDG F      TEL+VG +YC  GL +LSMC+NLIQDEI++KF W+G KLG++   +    +E  D+
Sbjct:  154 IGEPTAMLFKAFYLNICCCKCFIKRKCPEEKAVEESIREQQRQQSSWTTADESGKMPPAKVKDLVVVEEDDEEDDEEEDIVNIPISVTILLLILYILLGAAVFRIWEK-WTLIEGTYFSFITLSTIGFGDYVPGKDGPFNSMTVITELLVGALYCFFGLTVLSMCINLIQDEISAKFHWIGLKLGMVKRVEQPSDDESEDE 353          

HSP 3 Score: 68.5514 bits (166), Expect = 2.317e-8
Identity = 29/60 (48.33%), Postives = 43/60 (71.67%), Query Frame = 3
Query:  294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRI 473
            C +    +  S +GTF++VI Y++MGGFLF+YLE  NE+  C+ KY+KY +K NE++ RI
Sbjct:   84 CCKRFGSIMLSQLGTFVIVIFYVVMGGFLFQYLEVENEVSSCQTKYDKYLSKRNEAVDRI 143          
BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Match: A0A267FFS9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032347g1 PE=3 SV=1)

HSP 1 Score: 281.952 bits (720), Expect = 3.114e-85
Identity = 158/347 (45.53%), Postives = 231/347 (66.57%), Query Frame = 3
Query:  294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINE--GNHPDYEIED------------DENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLI 1289
            C +    +  S +GTF++VI Y++MGGFLF+YLE  NE+  C+ KY+KY +K NE++ RI  ++ + +      + +   ++ F+KD++ ++ +P  NCST+GQ  N+  WN  N+ +FCVT+ITTIGYG+I P T WG+I  MIY+I GIPLMLLFLT +GE  A  F+  YLN+CCC+CFI R+     + E   +     Q      +  G  P  +++D            +E   V IPI+V +++L +YI++GA +FRIWE+ W++++GTYFS+ITL+TIGFGD+VPGKDG F      TEL+VG +YC  GL +LSMC+NLIQDEI++KF W+G KLG++
Sbjct:   84 CCKRFGSIMLSQLGTFVIVIFYVVMGGFLFQYLEVENEVSSCQTKYDKYLSKRNEAVDRIYNMAQNGKNAVAAKASIFTEISDFAKDIYTLSMDPRLNCSTLGQGDNIPYWNFANAAYFCVTVITTIGYGHIAPGTSWGQIVCMIYAILGIPLMLLFLTKIGEPTAMLFKAFYLNICCCKCFIKRKCPEEKAVEESIREQQRQQSSWTTADESGKMPPAKVKDLVVVEEDDEEDDEEEDIVNIPISVTILLLILYILLGAAVFRIWEK-WTLIEGTYFSFITLSTIGFGDYVPGKDGPFNSMTVITELLVGALYCFFGLTVLSMCINLIQDEISAKFHWIGLKLGMV 429          
BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Match: A0A267FMF4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022638g1 PE=3 SV=1)

HSP 1 Score: 271.166 bits (692), Expect = 1.600e-81
Identity = 161/351 (45.87%), Postives = 240/351 (68.38%), Query Frame = 3
Query:  294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFI------SRRVEIVDSTENDKKLNIE-------GQPPPKINE-GNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSD 1301
            C++    +  SH+GTFL+V+ Y +MGGFLF+YLE  NEI  C+ K  K+  KL+ES+ +I  I+      +Q  S ++  +  F++D + +  +PS NC+T+    ++  WN+ N+ +FCVTIITTIGYG+I+P+T WG+I  MIYSI GIPLMLLFL+ +GE  A  FR  YLN+ CC+CF+      ++ +E +     + + + +        +PP K+    +  + E E++E+  V IPITV +I+L +YI++GA +F +WE+EW++V+GTYFS+ITL+TIGFGD+VPG+DG F   +  TEL+VG +YCL GLA+LSMC+NLIQDEI +KF+WLG K+G+I  + 
Sbjct:   72 CMKRFSSIMLSHLGTFLIVVLYTLMGGFLFQYLEVENEISGCQTKSEKFIAKLDESVDQIYNIAQGTNA-TQAKSAIQEELNQFAQDTYTLGVDPSMNCTTLKTGESMPSWNVANAAYFCVTIITTIGYGHISPVTQWGQIVCMIYSILGIPLMLLFLSKIGEPTAMLFRSFYLNIFCCKCFVKKLPNENKLMEAMQENGGNAQTSWQQVEEGDGKRPPAKVTVIEDDVEEEEENEEDDVVNIPITVTIILLILYILMGAAVFMVWEKEWTLVEGTYFSFITLSTIGFGDYVPGRDGPFNDIQVITELLVGCIYCLFGLAMLSMCINLIQDEIQAKFQWLGRKIGMIKKAQ 421          
BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Match: A0A267FK89 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018280g2 PE=3 SV=1)

HSP 1 Score: 270.781 bits (691), Expect = 2.251e-81
Identity = 161/350 (46.00%), Postives = 240/350 (68.57%), Query Frame = 3
Query:  294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFI------SRRVEIVDSTENDKKLNIE-------GQPPPKINE-GNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDS 1298
            C++    +  SH+GTFL+V+ Y +MGGFLF+YLE  NEI  C+ K  K+  KL+ES+ +I  I+      +Q  S ++  +  F++D + +  +PS NC+T+    ++  WN+ N+ +FCVTIITTIGYG+I+P+T WG+I  MIYSI GIPLMLLFL+ +GE  A  FR  YLN+ CC+CF+      ++ +E +     + + + +        +PP K+    +  + E E++E+  V IPITV +I+L +YI++GA +F +WE+EW++V+GTYFS+ITL+TIGFGD+VPG+DG F   +  TEL+VG +YCL GLA+LSMC+NLIQDEI +KF+WLG K+G+I  +
Sbjct:   72 CMKRFSSIMLSHLGTFLIVVLYTLMGGFLFQYLEVENEISGCQTKSEKFIAKLDESVDQIYNIAQGTNA-TQAKSAIQEELNQFAQDTYTLGVDPSMNCTTLKTGESMPSWNVANAAYFCVTIITTIGYGHISPVTQWGQIVCMIYSILGIPLMLLFLSKIGEPTAMLFRSFYLNIFCCKCFVKKLPNENKLMEAMQENGGNAQTSWQQVEEGDGKRPPAKVTVIEDDVEEEEENEEDDVVNIPITVTIILLILYILMGAAVFMVWEKEWTLVEGTYFSFITLSTIGFGDYVPGRDGPFNDIQVITELLVGCIYCLFGLAMLSMCINLIQDEIQAKFQWLGRKIGMIKKA 420          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Match: kcnk15 (potassium channel subfamily K member 15-like [Source:NCBI gene;Acc:103042097])

HSP 1 Score: 73.9442 bits (180), Expect = 8.167e-14
Identity = 66/205 (32.20%), Postives = 93/205 (45.37%), Query Frame = 3
Query:  621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235
            QW    S +F +T+ITTIGYG+  P TD GK+  M Y++ GIPL L+   ++GE M TF RF+      C  F  RR E+  S EN   +                                    +     + VGA  F  +E  W+     Y+ +ITL TIGFGDFV  +   +  E    ++   MY L+GL ++   LNL+
Sbjct:   77 QWKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFLLHRTKQCLGF--RRTEV--SMENMVLIGF----------------------------------LSCLGTLCVGAAAFSHFEG-WTFFHAYYYCFITLTTIGFGDFVALQKNEDLQEKTPYVVFSFMYILVGLTVIGAFLNLV 242          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Match: ENSAMXT00000047723.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:15897283:15919205:1 gene:ENSAMXG00000033807.1 transcript:ENSAMXT00000047723.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.929 bits (154), Expect = 1.553e-10
Identity = 56/178 (31.46%), Postives = 89/178 (50.00%), Query Frame = 3
Query:  327 HIGTFLMVITYIIMGGFLFKYLE---ENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNL-CCCRCFISR 848
            H    L +I Y ++G  LF  +E    N+  L   E + K+   ++E +      STS   + ++   LE       ++ FK  +  S +           +W+ Y S+FFC T+ TT+GYG I P+T  G++  ++Y+  GIPLMLL +T+VG+I+A  F   Y  L   CR  + R
Sbjct:  139 HAALILSLIVYALLGAALFHAIEGTQSNDGTLEIHEGFRKF---VHEVVNEARNKSTSANVSEEV---LEAVGEKILRE-FKAVWMQSSD-----------RWHFYGSLFFCCTVFTTVGYGEIYPVTKAGRVACILYATVGIPLMLLVITDVGDILAVLFSNSYRRLHSSCRRLLYR 298          

HSP 2 Score: 48.9062 bits (115), Expect = 8.382e-6
Identity = 25/68 (36.76%), Postives = 36/68 (52.94%), Query Frame = 3
Query: 1029 ACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNL 1232
            A +  IWE +    D  YF +ITL TIGFGD VP    F         ++  ++ ++G+AI+SM   L
Sbjct:  425 ALILPIWEDDLGKFDAFYFCFITLTTIGFGDIVPKHPKF--------FMLTFLFIIMGMAIMSMAFKL 484          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Match: kcnk9 (potassium two pore domain channel subfamily K member 9 [Source:NCBI gene;Acc:103047047])

HSP 1 Score: 63.5438 bits (153), Expect = 1.944e-10
Identity = 63/205 (30.73%), Postives = 88/205 (42.93%), Query Frame = 3
Query:  621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235
            QW    S +F +T+ITTIGYG+  P TD GK   M Y++ GIPL L+   ++GE M TF +  YL     +C   R  E+  S EN   +                                          + +GA  F  +E +WS     Y+ +ITL TIGFGDFV  +           +    MY L+GL ++   LNL+
Sbjct:  132 QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVK--YLLKRIKKCCGMRITEV--SMENMVTVGF----------------------------------FSCMGTLCIGAAAFSHYE-DWSFFQSYYYCFITLTTIGFGDFVALQKNRALQRKPLYVAFSFMYILVGLTVIGAFLNLV 297          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Match: kcnk1a (potassium channel subfamily K member 1-like [Source:NCBI gene;Acc:103029028])

HSP 1 Score: 62.3882 bits (150), Expect = 3.185e-10
Identity = 71/279 (25.45%), Postives = 124/279 (44.44%), Query Frame = 3
Query:  624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGL-AILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELAD-----DVEPFSYSTSQPQENQMKIMQTNFIENGSPQMLIKQTD 1442
            W+  +++FF  T+++T GYG+  PL+D GK   ++YS+ GIP  LLFLT                       + +R+ +  +      +         +  G H                  + LIV+  + ++ A +F + E+EW+ ++  YF +I+L+TIG GD+VPG +G+ +       +   +Y LLGL A+L +     + +   K R +           YL KE   D     D + FS+++       ++  +T+ I + SP   I  TD
Sbjct:  102 WDFTSALFFASTVLSTTGYGHTVPLSDEGKAFCILYSVVGIPFTLLFLTA----------------------VVQRIMVFSTRRPVAYVQRRWALSKPLVSGVHAG---------------LMALIVVSCFFLIPAIIFSVMEEEWNFLESFYFCFISLSTIGLGDYVPG-EGYNQKFRQLYKVGITVYLLLGLIAMLVVLETFCELQQLKKLRKMF----------YLKKEITEDQLNIVDHDHFSFASVSDPVASVRDYRTDLINDSSP---IAATD 329          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Match: kcnk1a (potassium channel subfamily K member 1-like [Source:NCBI gene;Acc:103029028])

HSP 1 Score: 58.5362 bits (140), Expect = 5.810e-9
Identity = 53/201 (26.37%), Postives = 94/201 (46.77%), Query Frame = 3
Query:  624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCL 1226
            W+  +++FF  T+++T GYG+  PL+D GK   ++YS+ GIP  LLFLT                       + +R+ +  +      +         +  G H                  + LIV+  + ++ A +F + E+EW+ ++  YF +I+L+TIG GD+VPG +G+ +       +   +Y LLGL  + + L
Sbjct:  102 WDFTSALFFASTVLSTTGYGHTVPLSDEGKAFCILYSVVGIPFTLLFLTA----------------------VVQRIMVFSTRRPVAYVQRRWALSKPLVSGVHAG---------------LMALIVVSCFFLIPAIIFSVMEEEWNFLESFYFCFISLSTIGLGDYVPG-EGYNQKFRQLYKVGITVYLLLGLIAMLVVL 264          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003416.1 (pep scaffold:Pmarinus_7.0:GL476517:78247:80718:1 gene:ENSPMAG00000003129.1 transcript:ENSPMAT00000003416.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.6406 bits (187), Expect = 3.407e-16
Identity = 73/208 (35.10%), Postives = 104/208 (50.00%), Query Frame = 3
Query:  621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLN-----LCCCRC--------------FISRRVEIVDSTEN---DKKLNIEGQPPPKINEGNH-----------PDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGF 1145
            +WN   S+FFC TI TTIGYG+I P TD GKI  M+Y+ FGIP+MLL L +VG+++A     IY +     L   RC                  R +I DS  +   D  +++  + P    EG              D    D E   + +P T++ +++F+Y++ G  L   WE EWS +D  YF ++T+ TIG GD VP    F
Sbjct:    1 KWNFLGSLFFCCTIFTTIGYGHIAPSTDGGKIMCMVYATFGIPIMLLVLADVGDLLARTLTTIYTSFRHRLLPGARCGRQHPPGDGPEGNDLQRSRTKIDDSHRHEGEDDAVDVPLKSPGSDVEGGRELPATVSIAEGADVPEADREVKELDVPFTLIFLIVFVYLMFGTFLLPCWE-EWSYLDAFYFVFVTMTTIGLGDIVPKHPNF 207          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Nematostella
Match: EDO43464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYH6])

HSP 1 Score: 62.3882 bits (150), Expect = 1.372e-10
Identity = 73/271 (26.94%), Postives = 122/271 (45.02%), Query Frame = 3
Query:  357 YIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIED--------DENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGF 1145
            Y+ +GG +F  LE + +    K   +K   ++   ++R    + S  +N   +S L++   + + D+ +     SK   +        QWNI NSI+FC+T+ TTIGYG++ P+T  G++  +IY++ GIPL L  L  VG+I+       Y+N  C                             K     +PDYE E+        D  +   + + ++++ +F  I  G C    W + W      YF ++T  TIGFGD VP  + +
Sbjct:   68 YLAIGGIIFMSLERSPK---AKIDTSKDLIEIFSVLKRSYIGNLSFPDN---VSSLDMVGNLTTADLHRFEKLLSKIHVSRALSAK-PQWNILNSIYFCMTVTTTIGYGSLAPVTVPGRVICVIYALLGIPLTLALLAVVGKIVGD-----YINDTCALVL-------------------------KWFRHLYPDYEYENMNQNQELGDGQIDAPLWLGLLILFIFTTITAGLC---CWMEGWDFGTSFYFQFVTYLTIGFGDVVPTSEKY 298          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Nematostella
Match: EDO33193 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSX6])

HSP 1 Score: 59.6918 bits (143), Expect = 5.108e-10
Identity = 60/208 (28.85%), Postives = 97/208 (46.63%), Query Frame = 3
Query:  606 PGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLN 1229
              NL QW+   S++F  T+ITTIGYG+  P T  GKI  MIY+  GIPL L    ++GE   TF       L C    + RR++        +KL ++                   D +    + +   L+ + I +  GA +F  +E+ W      Y+ +IT+ TIGFGD+V  +D  ++  +   + +  ++   GL I+   +N
Sbjct:   73 KANLYQWSFAGSVYFATTVITTIGYGHTVPRTPRGKIFCMIYAAVGIPLALTMFQSIGERFNTF-------LAC----MFRRLK--------RKLGMKA-----------------TDVSSTTNLVVVCGLLAMVITVSSGAFIFTHYEK-WDYFHSLYYCFITVTTIGFGDYVALQDSKDERYSNKYVGISLLFIFFGLTIVGSVMN 243          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Nematostella
Match: EDO46328 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQB1])

HSP 1 Score: 58.9214 bits (141), Expect = 6.997e-10
Identity = 69/265 (26.04%), Postives = 120/265 (45.28%), Query Frame = 3
Query:  342 LMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGK 1136
            +++  Y++ G  +F+ LE  NE        NK    LN      + ++  ++ N        I+   F   V K+       C    +   +++W+ Y S++F  +++TTIGYG++ P T  G+I  MI+++FGIPL L+ L N+G+ +     +++         ++ RV           +  EG P           +E+               L  +F  +++GA L+   E  W+  DG YF +IT +TIGFGD VP +
Sbjct:   29 ILLGVYLLSGAAVFQVLENENE--------NKDVVNLNS-----LRMTFCKKYN--------ISTEDFELLVGKVERATKYRCGGPPESWCMSRWSYYASLYFTWSVVTTIGYGHLAPSTLGGRIFCMIFALFGIPLNLMILKNLGDRIKDVIHYVHF-------LLATRV-----------MKREGDP-----------HEVA---------LCFSALGFMFAMLVIGAILYAQTEH-WNYFDGIYFCFITFSTIGFGDLVPNQ 233          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Nematostella
Match: EDO47668 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLC5])

HSP 1 Score: 47.3654 bits (111), Expect = 6.650e-6
Identity = 44/146 (30.14%), Postives = 78/146 (53.42%), Query Frame = 3
Query:  351 ITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRI-MAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGN-LAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGE 782
            I Y++MG  +F++LE  +E         K   ++ + IQRI    + SR+E  + +                   +  +  ++ G   + L +W+   S+FF  T+ITTIGYG+++P T +G+I  M+Y++FGIP+  L LT++G+
Sbjct:   20 ILYLVMGMVVFRFLESGHE--------KKEREQVQKDIQRIRHKFNISRKEMKEFV-------------------DVVQKAASFGLTQDWLEKWSYTGSLFFSGTVITTIGYGHLSPETFFGRIFCMLYALFGIPITWLMLTSLGK 138          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Match: kcnk3a (potassium two pore domain channel subfamily K member 3 [Source:NCBI gene;Acc:101167669])

HSP 1 Score: 74.7146 bits (182), Expect = 3.990e-14
Identity = 80/299 (26.76%), Postives = 128/299 (42.81%), Query Frame = 3
Query:  342 LMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLA-QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235
            L  +TY+I+G  +F  LE   E    K+   +      E ++    +STS                         ++E  +N   + +P     QWN   S +F +T+ITTIGYG+  P TD GK+  M+Y++ GIPL L+   ++GE + TF R++  +L   +C   RR E+     +   + I G                               L+     +  GA  F  +E  W+     Y+ +ITL TIGFGD+V  + G    E    ++   +Y L+GL ++   LNL+
Sbjct:   13 LCTLTYLIVGAAIFDALESKKETSQSKDLRAR-----KEDLRHRFNLSTS-------------------------DFEKLENVVLLLKPHKAGLQWNFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMLYALLGIPLTLVMFQSLGERINTFVRYLLHHL--KKCLGMRRTEV-----SMVNMVIVG-------------------------------LVSCMTTLCAGALAFSHFEG-WTFFQAYYYCFITLTTIGFGDYVALQKGEALQEKQGYVVFCFIYILMGLGVIGAFLNLV 242          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Match: kcnk15 (potassium channel subfamily K member 15 [Source:NCBI gene;Acc:101160319])

HSP 1 Score: 72.0182 bits (175), Expect = 3.476e-13
Identity = 65/205 (31.71%), Postives = 93/205 (45.37%), Query Frame = 3
Query:  621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235
            QW    S +F +T+ITTIGYG+  P TD GK+  M Y++ GIPL L+   ++GE M TF  F+   +   +C   RR E+  S EN   + +                                  +     + VGA  F  +E  WS     Y+ +ITL TIGFGDFV  +   +  E    +    MY L+GL ++   LNL+
Sbjct:   82 QWKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVHFLLHKV--KQCLGCRRTEV--SMENMVLVGL----------------------------------LSCVGTLCVGAAAFSHFEG-WSFFHAYYYCFITLTTIGFGDFVALQKKEDLQEKTPYVAFSFMYILVGLTVIGAFLNLV 247          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Match: kcnk1b (potassium two pore domain channel subfamily K member 1 [Source:NCBI gene;Acc:101174617])

HSP 1 Score: 59.6918 bits (143), Expect = 1.991e-9
Identity = 57/203 (28.08%), Postives = 97/203 (47.78%), Query Frame = 3
Query:  624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGM--YCLLGLAILSMCL 1226
            W+  +++FF  T+++T GYG+  PL+D GK   +IYS+ GIP  LLFLT V + +                F +RR  +   T         G   P +                 +V    + ++ +  + ++ A +F   E+ W+ ++  YF +I+L+TIG GD+VPG+   +K     EL   G+  Y +LGL ++ + L
Sbjct:  102 WDFTSALFFASTVLSTTGYGHTAPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRIMV--------------FTTRRPVVYIHTR-------WGLSKPLV----------------AIVHATLLAMLAVSCFFLIPAAIFSALEENWNFLESFYFCFISLSTIGLGDYVPGEAANQKFR---ELYKVGITVYLILGLIVMLVVL 264          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Match: kcnk1b (potassium two pore domain channel subfamily K member 1 [Source:NCBI gene;Acc:101174617])

HSP 1 Score: 59.6918 bits (143), Expect = 2.287e-9
Identity = 57/203 (28.08%), Postives = 97/203 (47.78%), Query Frame = 3
Query:  624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGM--YCLLGLAILSMCL 1226
            W+  +++FF  T+++T GYG+  PL+D GK   +IYS+ GIP  LLFLT V + +                F +RR  +   T         G   P +                 +V    + ++ +  + ++ A +F   E+ W+ ++  YF +I+L+TIG GD+VPG+   +K     EL   G+  Y +LGL ++ + L
Sbjct:  102 WDFTSALFFASTVLSTTGYGHTAPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRIMV--------------FTTRRPVVYIHTR-------WGLSKPLV----------------AIVHATLLAMLAVSCFFLIPAAIFSALEENWNFLESFYFCFISLSTIGLGDYVPGEAANQKFR---ELYKVGITVYLILGLIVMLVVL 264          
BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Match: kcnk18 (potassium two pore domain channel subfamily K member 18 [Source:NCBI gene;Acc:101159039])

HSP 1 Score: 58.151 bits (139), Expect = 9.096e-9
Identity = 47/175 (26.86%), Postives = 88/175 (50.29%), Query Frame = 3
Query:  294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLN 818
            CL    +V F H+     ++ Y ++G  +F+ +E  N+    +E Y ++  ++ + ++     ++  Q  S ++ ++E  M  F+   F+                N   W  + S+FFC T+ TT+GYG I P+T  GK+  ++Y++ GIPLMLL + +VG+ +A      Y+ 
Sbjct:   10 CLAPLWRV-FPHLALCGTLVAYAVLGALIFQRIEGGNKPSKIQEDYREFLGEIVDIVRNHSQNTSCSQ--SCMVDQVEKKMKTFNSIWFQ----------------NPDNWTFFGSMFFCCTVFTTVGYGEIYPVTLSGKVVCVLYAMVGIPLMLLVILDVGDFLALLMTKAYVQ 165          

HSP 2 Score: 52.373 bits (124), Expect = 5.610e-7
Identity = 25/79 (31.65%), Postives = 44/79 (55.70%), Query Frame = 3
Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262
            G  +  +WE++++  D  YF +ITL TIGFGD +P    +         ++  ++ ++G+AI+SM   L Q  I + +R
Sbjct:  305 GGLILPLWEKDFTDFDPYYFCFITLTTIGFGDIIPKHPNY--------FMLISLFIIVGMAIMSMAFKLSQTRIVTCYR 375          
BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Match: SMESG000024430.1 (SMESG000024430.1)

HSP 1 Score: 718.383 bits (1853), Expect = 0.000e+0
Identity = 385/385 (100.00%), Postives = 385/385 (100.00%), Query Frame = 3
Query:  291 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADDVEPFSYSTSQPQENQMKIMQTNFIENGSPQMLIKQTDC 1445
            TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVTIITTIGYGNITPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENVFVVIPITVVLIVLFIYIIVGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADDVEPFSYSTSQPQENQMKIMQTNFIENGSPQMLIKQTDC
Sbjct:   15 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVTIITTIGYGNITPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENVFVVIPITVVLIVLFIYIIVGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADDVEPFSYSTSQPQENQMKIMQTNFIENGSPQMLIKQTDC 399          
BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Match: SMESG000016405.1 (SMESG000016405.1)

HSP 1 Score: 272.707 bits (696), Expect = 1.547e-86
Identity = 172/381 (45.14%), Postives = 240/381 (62.99%), Query Frame = 3
Query:  321 FSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFI-------------SRR--VEIVD-STENDKKLN---IEGQPPPK-INEGNHPDY-EIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKE-ELADDVEPFSYSTSQPQENQMKIMQTN 1397
             SH GT  ++I Y+I GGFLF  LE+ NE   C   Y     KLN++  R ++I  S    +    ++   +  FSK+V+ + + PSK+C+TIGQP NL+ WN+ NSIFFC TIITTIGYGNI P T WG+I  +IY+  GIPLMLLFL+N GE++A+ FRF+Y NLCCCRCF+             S+R  +EI +   EN + LN   ++  PPPK I+E     Y + E+D++  + IP+TVV+  L IY+ +GA +F+IWE  W +V   YFS+IT++TIGFGD  P K+    +    ELIVG +YC++GLAILSMCLNL+++EI  KF WLGNKLG++  +    +E E  +D +  S    +  + Q  +M  N
Sbjct:   17 LSHFGTLFIIILYLIGGGFLFALLEQENEKSSCFTSYKLLMDKLNDTTYRGVSIGNSGYNATIYYQQMYSMLFNFSKEVYTLGFSPSKDCTTIGQPDNLSAWNLANSIFFCATIITTIGYGNIVPSTVWGRIVCIIYAFIGIPLMLLFLSNFGEVLASAFRFVYTNLCCCRCFVKGKYTSISEFESMSKRSAIEIKNFELENAENLNSNPVKATPPPKFIDEDLDIVYVDDENDQDEIINIPLTVVIGFLIIYMFLGALIFQIWET-WDLVAAVYFSFITVSTIGFGDLYPAKNTIGSSVATLELIVGAVYCIIGLAILSMCLNLVKEEIVEKFSWLGNKLGIVKSNTGSSEECEEVNDHQSNSRIIIENSDFQNSVMHVN 396          
BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Match: SMESG000016405.1 (SMESG000016405.1)

HSP 1 Score: 116.701 bits (291), Expect = 4.998e-30
Identity = 74/171 (43.27%), Postives = 109/171 (63.74%), Query Frame = 3
Query:  894 IEGQPPPK-INEGNHPDY-EIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKE-ELADDVEPFSYSTSQPQENQMKIMQTN 1397
            ++  PPPK I+E     Y + E+D++  + IP+TVV+  L IY+ +GA +F+IWE  W +V   YFS+IT++TIGFGD  P K+    +    ELIVG +YC++GLAILSMCLNL+++EI  KF WLGNKLG++  +    +E E  +D +  S    +  + Q  +M  N
Sbjct:   23 VKATPPPKFIDEDLDIVYVDDENDQDEIINIPLTVVIGFLIIYMFLGALIFQIWET-WDLVAAVYFSFITVSTIGFGDLYPAKNTIGSSVATLELIVGAVYCIIGLAILSMCLNLVKEEIVEKFSWLGNKLGIVKSNTGSSEECEEVNDHQSNSRIIIENSDFQNSVMHVN 192          
BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Match: SMESG000031911.1 (SMESG000031911.1)

HSP 1 Score: 105.145 bits (261), Expect = 9.583e-24
Identity = 93/262 (35.50%), Postives = 143/262 (54.58%), Query Frame = 3
Query:  609 GNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRV------EIVDSTENDKK----------LNIEGQPPPKINE------------------GNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGK-DGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLI 1289
            GN+  W    ++ + +TIITTIGYG+I P T  G+  +++Y+I GIPLMLL LTN+G++MA  F+F+Y    C + +I  R       +++DS  N +K          +NI  + P  I +                  GN    +   + +  V +PI + L +L +YI+VGA +F  W+  W+  +  YF +ITL TIGFGD VPG  +  EK++  T+ I    Y + GLA+ +MC  LIQ+++   F  LG ++GLI
Sbjct:  356 GNIL-WTFSGALLYSITIITTIGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKEITTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDG-WTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI 614          

HSP 2 Score: 50.0618 bits (118), Expect = 3.296e-6
Identity = 28/70 (40.00%), Postives = 42/70 (60.00%), Query Frame = 3
Query:  294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIM-AISTSRQE 500
            C + S+   FS IG   +V+ YII GGFLF+ LE  NEI + K       + +N+S++++M  I +S QE
Sbjct:  123 CCKQSIAFFFSQIGVMCIVVAYIIAGGFLFQNLEAKNEINISKSG----ESNINDSLKKLMEKIRSSEQE 188          
BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Match: SMESG000013544.1 (SMESG000013544.1)

HSP 1 Score: 85.5001 bits (210), Expect = 2.533e-17
Identity = 83/248 (33.47%), Postives = 132/248 (53.23%), Query Frame = 3
Query:  624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFI-----------------SRRVEIVDSTEN-DKKLNIEGQPPPKINEGNH----------------PDYEIE-DDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262
            W    SI +C+T+ITTIGYG+ITP T  G+  ++IY+IFGIP+ML+ L ++G +MA  FR IY  + C + F                  S   E++D +++ D ++++     P    GN+                P+  +E   ++  V +P+++V+ V  IY +VG+  F I E  W + D  YFS+ITL+TIGFGDFVP   G E  +  +  I+   Y L GL++  M  +L++ +  S  +
Sbjct:  426 WTFGGSILYCITVITTIGYGHITPKTIPGRFGTIIYAIFGIPIMLICLAHIGSLMANMFRLIY-RVSCLKAFKKYKKSQKSKCQNSEKQSSTSNELLDKSDDEDNQISLTVVKNPHNPTGNYFGSTVQFRKILFHIPNPNRLLEAAKKSKSVEVPVSLVITVFIIYNLVGSVFFTICEG-WKITDSFYFSFITLSTIGFGDFVPVAIGNEAEQYKS--IMCSFYVLFGLSLCVMSFDLMEKKCKSTIK 669          
The following BLAST results are available for this feature:
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCNK22.399e-835.90potassium two pore domain channel subfamily K memb... [more]
KCNK23.167e-835.90potassium two pore domain channel subfamily K memb... [more]
KCNK27.430e-835.90potassium two pore domain channel subfamily K memb... [more]
KCNK28.854e-835.90potassium two pore domain channel subfamily K memb... [more]
KCNK29.928e-835.90potassium two pore domain channel subfamily K memb... [more]
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BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
twk-485.375e-3130.08TWiK family of potassium channels [Source:UniProt... [more]
twk-393.875e-2042.34TWiK family of potassium channels [Source:UniProt... [more]
twk-393.060e-1946.59TWiK family of potassium channels [Source:UniProt... [more]
twk-284.461e-1927.06TWiK family of potassium channels [Source:UniProt... [more]
twk-407.191e-1827.84TWiK family of potassium channels [Source:UniProt... [more]
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BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG91942.370e-1932.69gene:FBgn0035192 transcript:FBtr0072651[more]
CG108643.120e-1726.35gene:FBgn0038621 transcript:FBtr0083654[more]
CG343962.693e-1425.86gene:FBgn0085425 transcript:FBtr0112645[more]
CG343962.058e-1324.14gene:FBgn0085425 transcript:FBtr0112644[more]
sand4.632e-1340.74gene:FBgn0033257 transcript:FBtr0088780[more]
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BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnk152.067e-1131.22potassium channel, subfamily K, member 15 [Source:... [more]
kcnk152.670e-1131.22potassium channel, subfamily K, member 15 [Source:... [more]
kcnk91.411e-1030.73potassium channel, subfamily K, member 9 [Source:Z... [more]
kcnk3a2.419e-1029.76potassium channel, subfamily K, member 3a [Source:... [more]
kcnk182.405e-927.98potassium channel, subfamily K, member 18 [Source:... [more]
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BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pole41.073e-1332.20polymerase (DNA-directed), epsilon 4, accessory su... [more]
pole42.133e-1332.09polymerase (DNA-directed), epsilon 4, accessory su... [more]
pole42.628e-1332.20polymerase (DNA-directed), epsilon 4, accessory su... [more]
KCNK181.984e-931.65potassium two pore domain channel subfamily K memb... [more]
prss1.23.514e-635.21protease, serine, 1 (trypsin 1), gene 2 [Source:Xe... [more]
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BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kcnk64.383e-1024.81potassium inwardly-rectifying channel, subfamily K... [more]
Kcnk189.523e-846.03potassium channel, subfamily K, member 18 [Source:... [more]
Kcnk29.768e-835.26potassium channel, subfamily K, member 2 [Source:M... [more]
Kcnk21.746e-735.26potassium channel, subfamily K, member 2 [Source:M... [more]
Kcnk21.957e-735.26potassium channel, subfamily K, member 2 [Source:M... [more]
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BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P34410|TWK7_CAEEL4.701e-1627.22TWiK family of potassium channels protein 7 OS=Cae... [more]
sp|Q18120|TWK18_CAEEL1.785e-1324.77TWiK family of potassium channels protein 18 OS=Ca... [more]
sp|O95069|KCNK2_HUMAN3.568e-735.90Potassium channel subfamily K member 2 OS=Homo sap... [more]
sp|Q7Z418|KCNKI_HUMAN6.415e-728.14Potassium channel subfamily K member 18 OS=Homo sa... [more]
sp|Q6VV64|KCNKI_MOUSE6.661e-746.03Potassium channel subfamily K member 18 OS=Mus mus... [more]
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BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8IZX52.218e-8750.15Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8HPD63.710e-8750.15Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267FFS93.114e-8545.53Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267FMF41.600e-8145.87Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267FK892.251e-8146.00Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnk158.167e-1432.20potassium channel subfamily K member 15-like [Sour... [more]
ENSAMXT00000047723.11.553e-1031.46pep primary_assembly:Astyanax_mexicanus-2.0:9:1589... [more]
kcnk91.944e-1030.73potassium two pore domain channel subfamily K memb... [more]
kcnk1a3.185e-1025.45potassium channel subfamily K member 1-like [Sourc... [more]
kcnk1a5.810e-926.37potassium channel subfamily K member 1-like [Sourc... [more]
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BLAST of Potassium channel subfamily K 8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000003416.13.407e-1635.10pep scaffold:Pmarinus_7.0:GL476517:78247:80718:1 g... [more]
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BLAST of Potassium channel subfamily K 8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Potassium channel subfamily K 8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO434641.372e-1026.94Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO331935.108e-1028.85Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO463286.997e-1026.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO476686.650e-630.14Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnk3a3.990e-1426.76potassium two pore domain channel subfamily K memb... [more]
kcnk153.476e-1331.71potassium channel subfamily K member 15 [Source:NC... [more]
kcnk1b1.991e-928.08potassium two pore domain channel subfamily K memb... [more]
kcnk1b2.287e-928.08potassium two pore domain channel subfamily K memb... [more]
kcnk189.096e-926.86potassium two pore domain channel subfamily K memb... [more]
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BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000024430.10.000e+0100.00SMESG000024430.1[more]
SMESG000016405.11.547e-8645.14SMESG000016405.1[more]
SMESG000016405.14.998e-3043.27SMESG000016405.1[more]
SMESG000031911.19.583e-2435.50SMESG000031911.1[more]
SMESG000013544.12.533e-1733.47SMESG000013544.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007122 ID=SMED30007122|Name=Potassium channel subfamily K 8|organism=Schmidtea mediterranea sexual|type=transcript|length=1506bp
AATTCTTGCAACTGATTATAAATTTATAAAAAAACAGCTTAAAAATGTTG
TCCCGAAATTGTTTTTCGAAAAAATCAATAACAAACAATTCCATGCCTTT
GTTATTACTGGATGTCAGAAGAATCGTTAAAATACAACAAATAGAGTTAG
AAAAGGTAAACAAAACCACTTTTGTTTTCATTCTGTAATAGGGAGAATTA
TTCGGTATATTACTTTTTAAAAAAATATAAAATTAATACAACTACTCAAT
GGACAACAATGAAAAAGAAAATAATAAACAAAAATGGAAAACTTGTTTAC
AAACCTCCATGAAAGTTGCCTTTTCTCACATTGGCACATTTTTAATGGTG
ATTACCTACATAATTATGGGAGGATTTCTTTTCAAATATCTTGAAGAAAA
CAATGAAATTCTGGTCTGCAAAGAGAAGTACAACAAATATTCCACGAAAC
TAAATGAAAGCATCCAACGCATAATGGCGATTTCTACCTCTCGACAAGAA
AACTCTCAAATTATGTCAGAACTCGAAATCACAATGACCATGTTCTCTAA
AGATGTGTTCAAAATAAATTATGAACCTAGCAAAAATTGTAGTACAATCG
GTCAGCCGGGAAATTTAGCCCAATGGAATATTTACAATAGCATATTTTTC
TGCGTCACAATTATAACAACAATTGGATATGGCAACATAACCCCCTTAAC
CGACTGGGGGAAAATTAACTCCATGATATATTCGATATTTGGCATTCCAT
TAATGTTATTATTTCTGACAAATGTCGGCGAAATTATGGCGACGTTTTTC
AGATTTATCTATCTTAATCTGTGCTGCTGTCGATGCTTCATAAGTCGGAG
AGTAGAAATTGTTGATTCAACCGAAAATGACAAAAAATTAAATATCGAGG
GTCAGCCACCTCCTAAGATAAATGAAGGAAATCATCCTGATTATGAAATT
GAGGATGATGAAAATGTATTTGTTGTTATCCCTATCACAGTTGTACTTAT
TGTACTGTTTATTTACATTATTGTTGGAGCTTGTTTATTTCGAATATGGG
AGCAAGAATGGTCAATGGTTGATGGAACTTACTTTTCTTATATTACTCTT
GCAACGATAGGCTTTGGAGATTTTGTGCCAGGGAAAGATGGATTTGAAAA
GGCTGAAACCGGAACTGAATTAATAGTTGGGGGAATGTACTGTTTGTTAG
GTCTGGCAATCCTGTCAATGTGCCTAAATCTTATTCAGGATGAAATTGCT
TCAAAATTCCGTTGGCTAGGAAACAAACTGGGATTAATTGATGATTCCGA
TTATTTGGACAAAGAGGAACTCGCTGACGACGTCGAACCTTTTTCTTATT
CAACTTCGCAACCTCAAGAGAACCAAATGAAAATAATGCAAACAAATTTC
ATTGAAAATGGTTCCCCACAAATGCTCATTAAACAAACTGATTGTTGAAT
ATTTTCACGGGACGCGGACTGGTTATTATTTTTCATTTGCAATGATTTCC
TCAAAT
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protein sequence of SMED30007122-orf-1

>SMED30007122-orf-1 ID=SMED30007122-orf-1|Name=SMED30007122-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=400bp
MDNNEKENNKQKWKTCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEE
NNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFS
KDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVTIITTIGYGNITPL
TDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISR
RVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENVFVVIPITVVL
IVLFIYIIVGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFE
KAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDS
DYLDKEELADDVEPFSYSTSQPQENQMKIMQTNFIENGSPQMLIKQTDC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000420parapharyngeal region
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR0032802pore_dom_K_chnl
IPR013099K_chnl_dom
Vocabulary: biological process
TermDefinition
GO:0071805potassium ion transmembrane transport
GO:0006810transport
GO:0006811ion transport
Vocabulary: molecular function
TermDefinition
GO:0005267potassium channel activity
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003280Two pore domain potassium channelPRINTSPR013332POREKCHANELcoord: 137..165
score: 50.57
coord: 285..294
score: 72.46
IPR013099Potassium channel domainPFAMPF07885Ion_trans_2coord: 251..332
e-value: 1.0E-15
score: 57.5
coord: 123..180
e-value: 2.5E-18
score: 65.8
NoneNo IPR availablePANTHERPTHR11003POTASSIUM CHANNEL, SUBFAMILY Kcoord: 19..340
NoneNo IPR availablePANTHERPTHR11003:SF276TWIK FAMILY OF POTASSIUM CHANNELScoord: 19..340
NoneNo IPR availableSUPERFAMILYSSF81324Voltage-gated potassium channelscoord: 243..344
NoneNo IPR availableSUPERFAMILYSSF81324Voltage-gated potassium channelscoord: 20..193
NoneNo IPR availableTMHMMTMhelixcoord: 242..264
NoneNo IPR availableTMHMMTMhelixcoord: 23..45
NoneNo IPR availableTMHMMTMhelixcoord: 160..182
NoneNo IPR availableTMHMMTMhelixcoord: 271..293
NoneNo IPR availableTMHMMTMhelixcoord: 308..330
NoneNo IPR availableTMHMMTMhelixcoord: 125..147