Potassium channel subfamily K 8
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30007122 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Match: KCNK2 (potassium two pore domain channel subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:6277]) HSP 1 Score: 56.225 bits (134), Expect = 2.399e-8 Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3 Query: 339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800 FL+V+ Y+I+G +FK LE+ +EI S + IQ+ IS NS + EL + V IN P N S ++ W++ +S FF T+ITTIG+GNI+P T+ GKI +IY++ GIPL L VG+ + T F Sbjct: 51 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 185
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Match: KCNK2 (potassium two pore domain channel subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:6277]) HSP 1 Score: 55.8398 bits (133), Expect = 3.167e-8 Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3 Query: 339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800 FL+V+ Y+I+G +FK LE+ +EI S + IQ+ IS NS + EL + V IN P N S ++ W++ +S FF T+ITTIG+GNI+P T+ GKI +IY++ GIPL L VG+ + T F Sbjct: 62 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 196
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Match: KCNK2 (potassium two pore domain channel subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:6277]) HSP 1 Score: 56.225 bits (134), Expect = 7.430e-8 Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3 Query: 339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800 FL+V+ Y+I+G +FK LE+ +EI S + IQ+ IS NS + EL + V IN P N S ++ W++ +S FF T+ITTIG+GNI+P T+ GKI +IY++ GIPL L VG+ + T F Sbjct: 66 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 200
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Match: KCNK2 (potassium two pore domain channel subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:6277]) HSP 1 Score: 55.8398 bits (133), Expect = 8.854e-8 Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3 Query: 339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800 FL+V+ Y+I+G +FK LE+ +EI S + IQ+ IS NS + EL + V IN P N S ++ W++ +S FF T+ITTIG+GNI+P T+ GKI +IY++ GIPL L VG+ + T F Sbjct: 51 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 185
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Match: KCNK2 (potassium two pore domain channel subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:6277]) HSP 1 Score: 55.8398 bits (133), Expect = 9.928e-8 Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3 Query: 339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800 FL+V+ Y+I+G +FK LE+ +EI S + IQ+ IS NS + EL + V IN P N S ++ W++ +S FF T+ITTIG+GNI+P T+ GKI +IY++ GIPL L VG+ + T F Sbjct: 62 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 196
BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Match: twk-48 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q7YWY7]) HSP 1 Score: 123.635 bits (309), Expect = 5.375e-31 Identity = 108/359 (30.08%), Postives = 174/359 (48.47%), Query Frame = 3 Query: 321 FSHIGTFLMVITYIIMGGFLFKYLEENNEILV---CKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEI--TMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYL------------------------NLCCCRCFISRRVEI---VDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSD 1301 FSHIG +V+ Y ++G +FK +E +E + K K + + R+ + S+Q ++ E++ T+ M S + Y+ + G AQW + + +T+ITTIGYGN T GK +M+Y+I GIPLMLLFLTN+G++MA FRF+Y N R RV+ VDS ++E ++ E + + +PI++V+ + Y+ VG +F++WE W+ ++ YF +I+L TIGFGD P E +L++ +Y L G+A+L+MC NL Q+E+ +K RW+ +K +D D Sbjct: 25 FSHIGLCALVVGYALLGAVIFKAVEGPHEAEIQELVKSAREKAVDVVWNATFRVNRLD-SKQWKKTVLDEVKRFKTVCMLS---IRKGYDGK-------EYGKQAQWTFTGAFLYSLTVITTIGYGNTAAKTYIGKTLTMLYAIIGIPLMLLFLTNIGDVMAKIFRFLYAQSIRLKFRLILWHKKRKAAKIRRANSLVSRLTRGHRVKADSSVDSFGLGAGADVEDLLTARVEMEQLEVRETAAAQLESMTVPISLVVFTMLGYLGVGTTIFKVWEG-WTFLESFYFCFISLTTIGFGDKFPSTSVSNTDEAQEKLVITSIYLLFGMALLAMCFNLAQEEVQNKTRWIADKFRSKEDDD 371
BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Match: twk-39 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:A1EHR5]) HSP 1 Score: 93.9745 bits (232), Expect = 3.875e-20 Identity = 47/111 (42.34%), Postives = 69/111 (62.16%), Query Frame = 3 Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADDVEPFSYSTS 1358 GA LF WE W+ DG Y+ +ITL+TIGFGD VPG+ E ++ +L+V +Y L G+A+++MC L+QD++ K RWLG K+G++ L +E + F YS S Sbjct: 508 GAWLFSWWEN-WNGFDGAYYCFITLSTIGFGDIVPGQALDEGSQE--KLVVCALYLLFGMALIAMCFKLMQDDVVQKARWLGQKIGILARPFELSREIAKHAIFLFGYSVS 615 HSP 2 Score: 73.9442 bits (180), Expect = 1.045e-13 Identity = 57/188 (30.32%), Postives = 96/188 (51.06%), Query Frame = 3 Query: 291 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQR------IMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRC 836 T ++++ +H+G +V Y + G F+F+ +E E L + K S K+ + I R ++ + + E+ + E E+ + V +N+E + QW ++ + +T+ TTIGYG+I P TD G++ +++YSI GIPLMLL L N+ E +A F +IY LCC C Sbjct: 14 TFVKSATIFTITHVGLCFLVALYAVAGAFMFQAVEYPYE-LGLQGKVKNASLKVVDDIYRFINRKNVIEETAVKNESQWALKEFEMLL------VHAMNFE---GYDEHDEERPTFQWTFSGALLYSITVFTTIGYGHICPKTDTGRLLTILYSILGIPLMLLCLANIAETLAQVFTYIYFKLCCAYC 191
BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Match: twk-39 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:A1EHR5]) HSP 1 Score: 91.2781 bits (225), Expect = 3.060e-19 Identity = 41/88 (46.59%), Postives = 61/88 (69.32%), Query Frame = 3 Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLI 1289 GA LF WE W+ DG Y+ +ITL+TIGFGD VPG+ E ++ +L+V +Y L G+A+++MC L+QD++ K RWLG K+G++ Sbjct: 508 GAWLFSWWEN-WNGFDGAYYCFITLSTIGFGDIVPGQALDEGSQE--KLVVCALYLLFGMALIAMCFKLMQDDVVQKARWLGQKIGIL 592 HSP 2 Score: 74.3294 bits (181), Expect = 8.328e-14 Identity = 57/188 (30.32%), Postives = 96/188 (51.06%), Query Frame = 3 Query: 291 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQR------IMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRC 836 T ++++ +H+G +V Y + G F+F+ +E E L + K S K+ + I R ++ + + E+ + E E+ + V +N+E + QW ++ + +T+ TTIGYG+I P TD G++ +++YSI GIPLMLL L N+ E +A F +IY LCC C Sbjct: 14 TFVKSATIFTITHVGLCFLVALYAVAGAFMFQAVEYPYE-LGLQGKVKNASLKVVDDIYRFINRKNVIEETAVKNESQWALKEFEMLL------VHAMNFE---GYDEHDEERPTFQWTFSGALLYSITVFTTIGYGHICPKTDTGRLLTILYSILGIPLMLLCLANIAETLAQVFTYIYFKLCCAYC 191
BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Match: twk-28 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q22940]) HSP 1 Score: 90.5077 bits (223), Expect = 4.461e-19 Identity = 92/340 (27.06%), Postives = 168/340 (49.41%), Query Frame = 3 Query: 312 KVAFSHIGTFLMVITYIIMGGFLFKYLEENNE----------ILVCKEKYNKYSTKLNE-SIQRIMAISTSRQENSQIMSEL--EITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEI----EDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKL 1280 K H+G +++ Y+I G FLF+YLE E IL ++++ + + + S RI SR+ + I E ++ MF ++ + +K+ + + W NS+FF T+ITTIGYGN+ P+T G++ +I+++ GIPL+L+ + ++G+ ++ F ++Y + + + R+ + + S + + G+ ++I ED + IP+ +VL+VL Y +G LF+ WE + YF +IT+AT+GFGD VP + + + Y + GL++ +MC++L E K +LG K+ Sbjct: 57 KRILPHVGLVILLFLYLIAGAFLFRYLEAPKELETRNHELTTILGLRDEFQDHIWNITQDSDNRI-----SREAFNAINQEYFEQLVKNMFQ--AYRNQFITAKHLLNKTREDEVL-WTFPNSMFFAATVITTIGYGNLVPITVTGRVACIIFALLGIPLLLVTIADIGKFLSEFLSYLYRSYRGFKRKLRRQSKKITSQYRSQSQSRSSSVMGSSKAGSMNLHDIDSDSEDSAGDELRIPVFMVLLVLLAYTAIGGFLFQSWEH-LEYFEAFYFCFITMATVGFGDIVPNEQVY--------VFFTMAYIIFGLSLATMCIDLAGTEYIRKIHYLGTKM 379
BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Match: twk-40 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q9XU07]) HSP 1 Score: 86.2705 bits (212), Expect = 7.191e-18 Identity = 93/334 (27.84%), Postives = 174/334 (52.10%), Query Frame = 3 Query: 300 QTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIG----QPGNLAQ---WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKL 1280 +T ++ +H+ ++ + Y+ G FLF LE+ NE+ V +++ + I+ + + S ++ +L + + +V +I +E + + IG +PG + W ++FF T++TTIGYGN+TP+T GK+ ++Y++FG+PL+L+ + ++G+ ++ +Y R S++ V S+++DK N EG D ++ EN ++ IPI +++ +L YI GA + +WE W G YFS+IT+ T+GFGD VP K + I+ Y ++GL+I +MC++L+ + K + G + Sbjct: 48 KTYARIILAHVSLIVLSVVYVGFGAFLFYQLEQPNEVEVRARNIERFNIHKRQMIEHLWEMRES-GIGQHVVEDLAVK---YVDNVTRILFE-AFDTHCIGAKHLRPGGEDEDYNWTYMTALFFTTTLLTTIGYGNLTPVTGRGKLLCILYALFGVPLILITVADIGKFLSENIVQLYTWYRKLREKCSKQKYSVISSKDDK--NKEG------------DLNLDHLEN-YISIPIFLIVAILLSYITFGAVVLSMWEG-WDFFSGFYFSFITMTTVGFGDIVPLKREY--------YILDLCYIIIGLSITTMCIDLVGIQYIRKMHYFGRAI 352
BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Match: CG9194 (gene:FBgn0035192 transcript:FBtr0072651) HSP 1 Score: 92.0485 bits (227), Expect = 2.370e-19 Identity = 68/208 (32.69%), Postives = 112/208 (53.85%), Query Frame = 3 Query: 324 SHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGN----LAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRC-FISRRVEIVDSTEND--KKLNIEGQPPPKINE 926 SH+ L+V++Y + G +LF++LE +E+ V ++ N L E+I + + +E S M+ + + F K + G G+ +QW S+F+ + +ITTIGYG+I+P TDWGK+ ++ Y+I GIPLML+ L+N+G++MAT FRF+Y +CC C ++R S + + + QPPP Sbjct: 40 SHVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQN-LRVNLTENIWLLSDDAVVLRE-SDWMANVSKHLANFEKQILTA-------IKADGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIGDVMATSFRFLYWRICCYVCTRTAKRPRNARSRQRSMRSQRHARSQPPPSFRR 238 HSP 2 Score: 77.7962 bits (190), Expect = 7.935e-15 Identity = 38/88 (43.18%), Postives = 54/88 (61.36%), Query Frame = 3 Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLI 1289 GA LF WE WS +D YF +ITL TIGFGDFVP K K E+ + +Y L G+A+L+M NL+Q+E + + + +LG++ Sbjct: 635 GAVLFAYWEN-WSFLDSAYFCFITLTTIGFGDFVPAKG--VKDESEQSIAYCSLYLLFGIALLAMSFNLVQEEFIANVKEVARRLGIL 719
BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Match: CG10864 (gene:FBgn0038621 transcript:FBtr0083654) HSP 1 Score: 83.9593 bits (206), Expect = 3.120e-17 Identity = 93/353 (26.35%), Postives = 159/353 (45.04%), Query Frame = 3 Query: 294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQ--WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPG---------------------KDGFE-------KAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262 C + + + +G +++ Y I G F F ++E V + + + N S Q++ +I+ E I+ T + DV + G G + W+ ++ FC+++IT IGYGN+ P T WGK ++IY+ FGIPL +L+ N+G ++A F+F+Y +L C R++ +D+ E + + P T L V+F Y++ G +F WE+ WS+++ YF +L IGFGDFVPG D E A+ ++L + +Y LLG+ +++MC NL+++E+ K R Sbjct: 39 CCRNFVTFMCTQVGVGALIVIYAICGAFAFMHIERQ---FVDETAGHVMELRQNCS-QQLWSIT----EQHNIIDRRRWTEA--TNDVLREYQSQIAGVVKHGYVGRSPEQIWSFPAALMFCLSVITMIGYGNMVPRTPWGKGFTVIYATFGIPLYILYFLNMGRVLARSFKFLYRSLHDC-TQEHPRLDRMDALEGGVGMTRKKVIVPS-----------------------TACLWVIFFYVLTGTVMFANWEK-WSLLNSFYFCMTSLCKIGFGDFVPGASLTTSADVNAATQKLQEDISADPAELAQLQSVAADQHSKLAINFVYMLLGMGLVAMCRNLMREEVRLKAR 356
BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Match: CG34396 (gene:FBgn0085425 transcript:FBtr0112645) HSP 1 Score: 76.2554 bits (186), Expect = 2.693e-14 Identity = 68/263 (25.86%), Postives = 129/263 (49.05%), Query Frame = 3 Query: 606 PGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMA-------TFFRFIYLNLCCCRCFISRRVEIV---------------------DSTENDKKLNIEGQPPPKINEGNHPD---------YEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLG 1283 PG + WN N FC T+ITTIGYG+ITP T G+ +++Y+I GIP+ L+ L ++G++ + R +Y C R +++ + END++ + + + +HP+ +E++D+ N+ V + +++ + + G+ F + E W+ +D Y+ +I+++TIGFGD VP + ++V +Y + GLA+ SM +N++Q +++ F+ K+G Sbjct: 609 PGQKS-WNFVNCFIFCWTVITTIGYGHITPKTGMGRSLTIVYAIIGIPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSMFFSNSAPENDEESQADAEAARSVG-TSHPETPTSPYPETFEVDDEFNLPVSVASLLLITYILL----GSFGFLMMEPSWTPLDAFYYVFISMSTIGFGDLVPSNPFY--------VMVSMIYLMFGLALTSMFINVVQIKLSDHFKMASAKVG 857
BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Match: CG34396 (gene:FBgn0085425 transcript:FBtr0112644) HSP 1 Score: 73.1738 bits (178), Expect = 2.058e-13 Identity = 63/261 (24.14%), Postives = 128/261 (49.04%), Query Frame = 3 Query: 612 NLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMA-------TFFRFIYLNLCCCRCFISRRVEIV---------------------DSTENDKKLNIEGQPPPKINEGNHPD---------YEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLG 1283 N W+ ++++ + TI TTIGYG+ITP T G+ +++Y+I GIP+ L+ L ++G++ + R +Y C R +++ + END++ + + + +HP+ +E++D+ N+ V + +++ + + G+ F + E W+ +D Y+ +I+++TIGFGD VP + ++V +Y + GLA+ SM +N++Q +++ F+ K+G Sbjct: 199 NTDPWSFWDAMVYSATIYTTIGYGHITPKTGMGRSLTIVYAIIGIPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSMFFSNSAPENDEESQADAEAARSVGT-SHPETPTSPYPETFEVDDEFNLPVSVASLLLITYILL----GSFGFLMMEPSWTPLDAFYYVFISMSTIGFGDLVPSNPFY--------VMVSMIYLMFGLALTSMFINVVQIKLSDHFKMASAKVG 446
BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Match: sand (gene:FBgn0033257 transcript:FBtr0088780) HSP 1 Score: 71.2478 bits (173), Expect = 4.632e-13 Identity = 33/81 (40.74%), Postives = 53/81 (65.43%), Query Frame = 3 Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGF--EKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262 GA LF WE +W+ +DG+YF I+L++IGFGD VPG ++ + I+ +Y LLG+A+++MC NL+Q+++ R Sbjct: 301 GALLFGRWE-DWNYLDGSYFCLISLSSIGFGDLVPGDRVITADRDKVEVSFILCAIYLLLGMAVIAMCFNLMQEQVVHNIR 380 HSP 2 Score: 70.0922 bits (170), Expect = 1.287e-12 Identity = 55/178 (30.90%), Postives = 100/178 (56.18%), Query Frame = 3 Query: 321 FSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFK-------INYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCR 833 FS++G L+V YII G F+F+ +E +Y +E R +A + S + S+I ++ F ++ ++Y+ + + P ++ QW+ + + +T+ITTIGYGNITP ++ GK+ +++Y+I G+PL LL+L+N+G+++A F++IY +C CR Sbjct: 31 FSNVGIILLVTFYIIGGAFIFQSIE-----------IFEYERLKSEKPHRFIARNFSGECLSRIWELTAENISFFDHHAYRRRVNDVLLDYQRAIVKKQLKGP-DVEQWSFSGAFLYSLTVITTIGYGNITPHSECGKLVTILYAIIGMPLFLLYLSNIGDVLAKSFKWIYSKVCLCR 196
BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Match: kcnk15 (potassium channel, subfamily K, member 15 [Source:ZFIN;Acc:ZDB-GENE-080220-30]) HSP 1 Score: 66.2402 bits (160), Expect = 2.067e-11 Identity = 64/205 (31.22%), Postives = 94/205 (45.85%), Query Frame = 3 Query: 621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235 QW S +F +T+ITTIGYG+ P TD GK+ M+Y+ GIPL L+ ++GE M T RF+ + R +R EI ST+N + + + + VGA F +E W+ Y+ +ITL TIGFGDFV + + E ++ +Y LLGL ++ LNL+ Sbjct: 77 QWRFAGSFYFAITVITTIGYGHAAPGTDAGKLFCMLYAGLGIPLTLVMFQSLGERMNTGVRFLLSRMK--RALGLQRTEI--STQNMVLVGV----------------------------------LSCLGTLCVGAAAFSHFE-SWTFFHAYYYCFITLTTIGFGDFVALQKKEDLQENQPYVLFSFIYILLGLTVIGAFLNLV 242
BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Match: kcnk15 (potassium channel, subfamily K, member 15 [Source:ZFIN;Acc:ZDB-GENE-080220-30]) HSP 1 Score: 65.4698 bits (158), Expect = 2.670e-11 Identity = 64/205 (31.22%), Postives = 94/205 (45.85%), Query Frame = 3 Query: 621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235 QW S +F +T+ITTIGYG+ P TD GK+ M+Y+ GIPL L+ ++GE M T RF+ + R +R EI ST+N + + + + VGA F +E W+ Y+ +ITL TIGFGDFV + + E ++ +Y LLGL ++ LNL+ Sbjct: 77 QWRFAGSFYFAITVITTIGYGHAAPGTDAGKLFCMLYAGLGIPLTLVMFQSLGERMNTGVRFLLSRMK--RALGLQRTEI--STQNMVLVGV----------------------------------LSCLGTLCVGAAAFSHFE-SWTFFHAYYYCFITLTTIGFGDFVALQKKEDLQENQPYVLFSFIYILLGLTVIGAFLNLV 242
BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Match: kcnk9 (potassium channel, subfamily K, member 9 [Source:ZFIN;Acc:ZDB-GENE-070705-260]) HSP 1 Score: 64.3142 bits (155), Expect = 1.411e-10 Identity = 63/205 (30.73%), Postives = 89/205 (43.41%), Query Frame = 3 Query: 621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235 QW S +F +T+ITTIGYG+ P TD GK M Y++ GIPL L+ ++GE M TF + YL +C R E+ S EN + + +GA F +E +WS Y+ +ITL TIGFGDFV + + + MY L+GL ++ LNL+ Sbjct: 168 QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVK--YLLKRIKKCCGMRITEV--SMENMVTVGF----------------------------------FSCMGTLCIGAAAFSQYE-DWSFFQSYYYCFITLTTIGFGDFVALQKNKALQKKPLYVAFSFMYILVGLTVIGAFLNLV 333
BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Match: kcnk3a (potassium channel, subfamily K, member 3a [Source:ZFIN;Acc:ZDB-GENE-040724-171]) HSP 1 Score: 63.1586 bits (152), Expect = 2.419e-10 Identity = 61/205 (29.76%), Postives = 90/205 (43.90%), Query Frame = 3 Query: 621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235 QW S +F +T+ITTIGYG+ P TD GK+ M Y++ GIPL L+ ++GE + TF +++ L +C R E+ S N + + I + VGA F +E +WS Y+ +ITL TIGFGD+V + + MY L GL ++ LNL+ Sbjct: 77 QWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTFVKYLLHRL--KKCLGLRHTEV--SMANMVCIGL----------------------------------ISCMSTLCVGAAAFSRYE-DWSFFHAYYYCFITLTTIGFGDYVALQKDNALQTNPQYVAFSFMYILTGLTVIGAFLNLV 242
BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Match: kcnk18 (potassium channel, subfamily K, member 18 [Source:ZFIN;Acc:ZDB-GENE-100405-2]) HSP 1 Score: 60.077 bits (144), Expect = 2.405e-9 Identity = 47/168 (27.98%), Postives = 84/168 (50.00%), Query Frame = 3 Query: 321 FSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFK-INYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNL 821 F H+ L ++ Y ++G +F+ +E N S ++ +Q++M I + + S+ + + +KD+ YE ++ W + S+FFC T+ TT+GYG I PLT GK+ ++Y++ GIPLMLL +++VG+++A Y L Sbjct: 21 FPHVFLILSLVLYAVLGALVFRAIEYKNP--------RNESEEILSIVQKVMEIVQNHTDTSE-----QKHLINKAKDILDDYCYEKERDHG----------WTFFASLFFCCTVFTTVGYGRIYPLTSKGKVACVLYAMVGIPLMLLVISDVGDLLAVLLSKAYTRL 165 HSP 2 Score: 53.9138 bits (128), Expect = 2.331e-7 Identity = 27/76 (35.53%), Postives = 41/76 (53.95%), Query Frame = 3 Query: 1035 LFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262 + + WE++ D YF++ITL TIGFGD VP F +V ++ + G+AI+SM L Q +I +R Sbjct: 304 ILKCWEKQMDHSDAFYFTFITLTTIGFGDIVPEHPKF--------FMVTFLFIITGMAIMSMAFKLGQSQIVCFYR 371
BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Match: pole4 (polymerase (DNA-directed), epsilon 4, accessory subunit [Source:Xenbase;Acc:XB-GENE-5722002]) HSP 1 Score: 74.3294 bits (181), Expect = 1.073e-13 Identity = 66/205 (32.20%), Postives = 94/205 (45.85%), Query Frame = 3 Query: 621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235 QW S +F +T+ITTIGYG+ P TD GK+ M Y++ GIPL L+ ++GE M TF RF+ L RCF R+ E+ S EN + V + + +GA F +E W+ Y+ +ITL TIGFGDFV + + + MY L+GL ++ LNL+ Sbjct: 89 QWKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFLLKKL--KRCFRLRKTEV--SMEN----------------------------------MVLVGFLSCIGTLGIGAAAFSYFEG-WTFFHSYYYCFITLTTIGFGDFVALQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLV 254
BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Match: pole4 (polymerase (DNA-directed), epsilon 4, accessory subunit [Source:Xenbase;Acc:XB-GENE-5722002]) HSP 1 Score: 73.559 bits (179), Expect = 2.133e-13 Identity = 69/215 (32.09%), Postives = 99/215 (46.05%), Query Frame = 3 Query: 591 STIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235 +TIG+ QW S +F +T+ITTIGYG+ P TD GK+ M Y++ GIPL L+ ++GE M TF RF+ L RCF R+ E+ S EN + V + + +GA F +E W+ Y+ +ITL TIGFGDFV + + + MY L+GL ++ LNL+ Sbjct: 93 TTIGK-----QWKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFLLKKL--KRCFRLRKTEV--SMEN----------------------------------MVLVGFLSCIGTLGIGAAAFSYFEG-WTFFHSYYYCFITLTTIGFGDFVALQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLV 263
BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Match: pole4 (polymerase (DNA-directed), epsilon 4, accessory subunit [Source:Xenbase;Acc:XB-GENE-5722002]) HSP 1 Score: 73.1738 bits (178), Expect = 2.628e-13 Identity = 66/205 (32.20%), Postives = 94/205 (45.85%), Query Frame = 3 Query: 621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235 QW S +F +T+ITTIGYG+ P TD GK+ M Y++ GIPL L+ ++GE M TF RF+ L RCF R+ E+ S EN + V + + +GA F +E W+ Y+ +ITL TIGFGDFV + + + MY L+GL ++ LNL+ Sbjct: 78 QWKFTGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFLLKKL--KRCFRLRKTEV--SMEN----------------------------------MVLVGFLSCIGTLGIGAAAFSYFEG-WTFFHSYYYCFITLTTIGFGDFVALQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLV 243
BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Match: KCNK18 (potassium two pore domain channel subfamily K member 18 [Source:HGNC Symbol;Acc:HGNC:19439]) HSP 1 Score: 60.8474 bits (146), Expect = 1.984e-9 Identity = 25/79 (31.65%), Postives = 44/79 (55.70%), Query Frame = 3 Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262 GAC+ +WE +W+ +D YF ++TL TIGFGD +P + ++ Y ++G+ I+ M L Q+ + S ++ Sbjct: 268 GACILPLWEDDWTTIDAFYFCFVTLTTIGFGDIIPKHPNY--------FLLLSAYTVVGMVIVCMAFKLGQNRLVSFYK 338
BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Match: prss1.2 (protease, serine, 1 (trypsin 1), gene 2 [Source:Xenbase;Acc:XB-GENE-6083469]) HSP 1 Score: 50.447 bits (119), Expect = 3.514e-6 Identity = 25/71 (35.21%), Postives = 43/71 (60.56%), Query Frame = 3 Query: 1029 ACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQD 1241 A +F E+ W VD YF +I+L+TIG GD+VPG+ ++ +L+V Y L+GL + + + +I++ Sbjct: 187 AIVFNAIEENWGYVDALYFCFISLSTIGLGDYVPGERNEQRLPVLYKLLV-ICYLLIGLVAVFLVVEVIKN 256
BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Match: Kcnk6 (potassium inwardly-rectifying channel, subfamily K, member 6 [Source:MGI Symbol;Acc:MGI:1891291]) HSP 1 Score: 62.003 bits (149), Expect = 4.383e-10 Identity = 64/258 (24.81%), Postives = 119/258 (46.12%), Query Frame = 3 Query: 624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADDVEPFSYSTSQPQENQMKIMQTN 1397 W+ +++FF T++TT+GYG TPLTD GK S+++++ G+P+ +L LT + R+ ++ + L++ PP+ H + ++++++ I+ +V A +F E+ WS +D YF +I+L+TIG GD+VPG+ + +++V Y LGL + + L FR + + GL EL +P S SQ +++Q+ ++ Sbjct: 91 WDFASALFFASTLVTTVGYGYTTPLTDAGKAFSIVFALLGVPITMLLLTASAQ----------------------RLSLLLTHAPLSWLSLHWGWPPQRAARWH---------------LVALLMVIVAIFFLVPAAVFAYLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTA-YLFLGLVAMVLVLQ--------TFRRVSDLHGL---------TELILLPDPDPASLSQDEDDQVAVLDAR 293
BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Match: Kcnk18 (potassium channel, subfamily K, member 18 [Source:MGI Symbol;Acc:MGI:2685627]) HSP 1 Score: 55.4546 bits (132), Expect = 9.523e-8 Identity = 29/63 (46.03%), Postives = 46/63 (73.02%), Query Frame = 3 Query: 624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIY 812 W+ +++FFC T+ +T+GYG++ P+T GK M+Y++FGIPLM L LT++G+I+AT Y Sbjct: 112 WSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLVLTDIGDILATILSRAY 174
BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Match: Kcnk2 (potassium channel, subfamily K, member 2 [Source:MGI Symbol;Acc:MGI:109366]) HSP 1 Score: 53.9138 bits (128), Expect = 9.768e-8 Identity = 55/156 (35.26%), Postives = 80/156 (51.28%), Query Frame = 3 Query: 339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800 FL+V+ Y+I+G +FK LE+ EI S + IQ+ I+ NS + EL + V IN P N S ++ W++ +S FF T+ITTIG+GNI+P T+ GKI +IY++ GIPL L VG+ + T F Sbjct: 62 FLVVVLYLIIGATVFKALEQPQEI----------SQRTTIVIQKQTFIAQHACVNSTELDEL------IQQIVAAINAGIIPLGNSSN-----QVSHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 196
BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Match: Kcnk2 (potassium channel, subfamily K, member 2 [Source:MGI Symbol;Acc:MGI:109366]) HSP 1 Score: 54.6842 bits (130), Expect = 1.746e-7 Identity = 55/156 (35.26%), Postives = 80/156 (51.28%), Query Frame = 3 Query: 339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800 FL+V+ Y+I+G +FK LE+ EI S + IQ+ I+ NS + EL + V IN P N S ++ W++ +S FF T+ITTIG+GNI+P T+ GKI +IY++ GIPL L VG+ + T F Sbjct: 66 FLVVVLYLIIGATVFKALEQPQEI----------SQRTTIVIQKQTFIAQHACVNSTELDEL------IQQIVAAINAGIIPLGNSSN-----QVSHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 200
BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Match: Kcnk2 (potassium channel, subfamily K, member 2 [Source:MGI Symbol;Acc:MGI:109366]) HSP 1 Score: 54.299 bits (129), Expect = 1.957e-7 Identity = 55/156 (35.26%), Postives = 80/156 (51.28%), Query Frame = 3 Query: 339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800 FL+V+ Y+I+G +FK LE+ EI S + IQ+ I+ NS + EL + V IN P N S ++ W++ +S FF T+ITTIG+GNI+P T+ GKI +IY++ GIPL L VG+ + T F Sbjct: 54 FLVVVLYLIIGATVFKALEQPQEI----------SQRTTIVIQKQTFIAQHACVNSTELDEL------IQQIVAAINAGIIPLGNSSN-----QVSHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 188
BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Match: sp|P34410|TWK7_CAEEL (TWiK family of potassium channels protein 7 OS=Caenorhabditis elegans OX=6239 GN=twk-7 PE=3 SV=3) HSP 1 Score: 84.7297 bits (208), Expect = 4.701e-16 Identity = 92/338 (27.22%), Postives = 165/338 (48.82%), Query Frame = 3 Query: 291 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAIS----TSRQE----NSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKL 1280 T ++ K+ H+ L+ TY ++G +F +E+ +E ++ +++ T+ NE + ++ ++ T R E + M + + + + F + E KN +T W +SIFF VT++TTIGYGN P+T+ G+I +++S+ GIPL L+ + ++G+ ++ ++Y N + I R +K E + G D IE+ IP +VL +L +Y G L E WS Y+S+IT+ T+GFGD +P +DG+ + + +Y +LGLAI +MC++L+ + K + G K+ Sbjct: 153 TGIRKFAKLVLPHVALVLLTCTYTVIGALIFYSVEQPHEQMMKEQQLKLIYTRQNEFVDDLIRLAAGNETKRYEWESLAERHMHNMSDQLFVAFEKYFLTSNEVKKNAAT-------ETWTFSSSIFFAVTVVTTIGYGNPVPVTNIGRIWCILFSLLGIPLTLVTIADLGKFLSEHLVWLYGNYLKLKYLILSR---------HRKERREHVCEHCHSHGMGHDMNIEEKR-----IPAFLVLAILIVYTAFGGVLMSKLEP-WSFFTSFYWSFITMTTVGFGDLMPRRDGY--------MYIILLYIILGLAITTMCIDLVGVQYIRKIHYFGRKI 460
BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Match: sp|Q18120|TWK18_CAEEL (TWiK family of potassium channels protein 18 OS=Caenorhabditis elegans OX=6239 GN=twk-18 PE=1 SV=2) HSP 1 Score: 76.2554 bits (186), Expect = 1.785e-13 Identity = 81/327 (24.77%), Postives = 153/327 (46.79%), Query Frame = 3 Query: 291 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSE----LEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRV--EIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIAS 1253 + + T+ + F + ++++ Y ++G ++F +E NE + E+ + + ++ +I + RQ E +T F + + + + K+ W SIF+C+T+ TTIGYGNI P T WG+ +++Y+ GIPL +L L +G + A + ++ +S+ + +I ++ +N ++ P + E N D + PI+ +L++ I++I A LF E EW YF+ I+ TIGFGD +P F + + G+ L+GL+++S + LIQ +I + Sbjct: 9 STILTTFQKTFKGLLPLIILVAYTLLGAWIFWMIEGENEREMLIEQQKERDELIRRTVYKINQLQIKRQRRLMTAEEEYNRTAKVLTTFQETLGIVPADMDKDI----------HWTFLGSIFYCMTVYTTIGYGNIVPGTGWGRFATILYAFIGIPLTVLSLYCLGSLFAKGCKMLWRFFLKSTRVVSKDLSNKISEAADNIEEGTTAITPSAEKTENNDDD---------LLSFPISGLLLITVIWVIFCAVLFTFLE-EWDFGTSLYFTLISFTTIGFGDILPSDYDF--------MPIVGVLLLIGLSLVSTVMTLIQQQIEA 307
BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Match: sp|O95069|KCNK2_HUMAN (Potassium channel subfamily K member 2 OS=Homo sapiens OX=9606 GN=KCNK2 PE=1 SV=2) HSP 1 Score: 56.225 bits (134), Expect = 3.568e-7 Identity = 56/156 (35.90%), Postives = 81/156 (51.92%), Query Frame = 3 Query: 339 FLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYE--PSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFF 800 FL+V+ Y+I+G +FK LE+ +EI S + IQ+ IS NS + EL + V IN P N S ++ W++ +S FF T+ITTIG+GNI+P T+ GKI +IY++ GIPL L VG+ + T F Sbjct: 66 FLVVVLYLIIGATVFKALEQPHEI----------SQRTTIVIQKQTFISQHSCVNSTELDEL------IQQIVAAINAGIIPLGNTSN-----QISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 200
BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Match: sp|Q7Z418|KCNKI_HUMAN (Potassium channel subfamily K member 18 OS=Homo sapiens OX=9606 GN=KCNK18 PE=1 SV=1) HSP 1 Score: 55.4546 bits (132), Expect = 6.415e-7 Identity = 47/167 (28.14%), Postives = 82/167 (49.10%), Query Frame = 3 Query: 294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMAT 794 C ++ F + ++TY ++G +F +E + ++LV + + K E + RI+ S + E+ + +L+ + F W+ +S+FFC T+ +T+GYG I P+T GK M+Y++FGIPLM L LT+ G+I+AT Sbjct: 12 CCPEALGKLFPGLCFLCFLVTYALVGAVVFSAIE-DGQVLVAAD--DGEFEKFLEELCRILNCSETVVEDRK--QDLQGHLQKVKPQWF----------------NRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILAT 157
BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Match: sp|Q6VV64|KCNKI_MOUSE (Potassium channel subfamily K member 18 OS=Mus musculus OX=10090 GN=Kcnk18 PE=1 SV=1) HSP 1 Score: 55.4546 bits (132), Expect = 6.661e-7 Identity = 29/63 (46.03%), Postives = 46/63 (73.02%), Query Frame = 3 Query: 624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIY 812 W+ +++FFC T+ +T+GYG++ P+T GK M+Y++FGIPLM L LT++G+I+AT Y Sbjct: 112 WSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLVLTDIGDILATILSRAY 174
BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Match: A0A1I8IZX5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 293.508 bits (750), Expect = 2.218e-87 Identity = 170/339 (50.15%), Postives = 232/339 (68.44%), Query Frame = 3 Query: 315 VAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAIS---TSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKK--LNIE-------GQPPPKINE--GNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGL 1286 + SH+GT +VI Y+IMGGFLF YLEE NE C Y+KY K NE+ R+ I+ S S I+S+LE+ F+KD++ ++ +P+KNCSTIG N A W + N+I+FC TI+TTIGYG+I+P T WG+I MIY+I GIPLMLLFLT +GE A FR YLN+CCC+CF+ RR + E + N+E QPPPK+ D +D ++ V IPITV +++L +YI+VGA +F WE++W++V+GTYFS+ITL+TIGFGD+VPG++G F+ EL+VG +YCL GLA+LSMC+NLIQDEI +K RW+GNK+G+ Sbjct: 323 IMLSHLGTLTLVIIYLIMGGFLFNYLEETNEKSACSIAYSKYEAKRNEATDRVYNIAQGANSSLSKSAILSQLEV----FAKDIYTLSVDPTKNCSTIGTVDNPANWVLANAIYFCTTIVTTIGYGHISPTTQWGQIICMIYAILGIPLMLLFLTKIGEPTAMLFRSFYLNICCCKCFVKRRHPAQSAGEQQQTEWRNVEDGGDGQAKQPPPKVGTVLVVEEDDNDDDFDDEVVNIPITVTIMLLILYILVGAAVFTAWEKDWTLVEGTYFSFITLSTIGFGDYVPGRNGPFDDVSVIMELLVGAIYCLFGLAMLSMCMNLIQDEITAKLRWIGNKMGI 657 HSP 2 Score: 144.821 bits (364), Expect = 3.309e-33 Identity = 84/187 (44.92%), Postives = 121/187 (64.71%), Query Frame = 3 Query: 774 VGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINE--GNHPDYEIED------------DENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLI 1289 +GE A F+ YLN+CCC+CFI R+ + E + Q + G P +++D +E V IPI+V +++L +YI++GA +FRIWE+ W++++GTYFS+ITL+TIGFGD+VPGKDG F TEL+VG +YC GL +LSMC+NLIQDEI++KF W+G KLG++ Sbjct: 118 IGEPTAMLFKAFYLNICCCKCFIKRKCPEEKAVEESIREQQRQQSSWTTADESGKMPPAKVKDLVVVEEDDEEDDEEEDIVNIPISVTILLLILYILLGAAVFRIWEK-WTLIEGTYFSFITLSTIGFGDYVPGKDGPFNSMTVITELLVGALYCFFGLTVLSMCINLIQDEISAKFHWIGLKLGMV 303
BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Match: A0A1I8HPD6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 293.893 bits (751), Expect = 3.710e-87 Identity = 170/339 (50.15%), Postives = 232/339 (68.44%), Query Frame = 3 Query: 315 VAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAIS---TSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKK--LNIE-------GQPPPKINE--GNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGL 1286 + SH+GT +VI Y+IMGGFLF YLEE NE C Y+KY K NE+ R+ I+ S S I+S+LE+ F+KD++ ++ +P+KNCSTIG N A W + N+I+FC TI+TTIGYG+I+P T WG+I MIY+I GIPLMLLFLT +GE A FR YLN+CCC+CF+ RR + E + N+E QPPPK+ D +D ++ V IPITV +++L +YI+VGA +F WE++W++V+GTYFS+ITL+TIGFGD+VPG++G F+ EL+VG +YCL GLA+LSMC+NLIQDEI +K RW+GNK+G+ Sbjct: 357 IMLSHLGTLTLVIIYLIMGGFLFNYLEETNEKSACSIAYSKYEAKRNEATDRVYNIAQGANSSLSKSAILSQLEV----FAKDIYTLSVDPTKNCSTIGTVDNPANWVLANAIYFCTTIVTTIGYGHISPTTQWGQIICMIYAILGIPLMLLFLTKIGEPTAMLFRSFYLNICCCKCFVKRRHPAQSAGEQQQTEWRNVEDGGDGQAKQPPPKVGTVLVVEEDDNDDDFDDEVVNIPITVTIMLLILYILVGAAVFTAWEKDWTLVEGTYFSFITLSTIGFGDYVPGRNGPFDDVSVIMELLVGAIYCLFGLAMLSMCMNLIQDEITAKLRWIGNKMGI 691 HSP 2 Score: 146.747 bits (369), Expect = 8.718e-34 Identity = 86/201 (42.79%), Postives = 126/201 (62.69%), Query Frame = 3 Query: 774 VGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINE--GNHPDYEIED------------DENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADD 1331 +GE A F+ YLN+CCC+CFI R+ + E + Q + G P +++D +E V IPI+V +++L +YI++GA +FRIWE+ W++++GTYFS+ITL+TIGFGD+VPGKDG F TEL+VG +YC GL +LSMC+NLIQDEI++KF W+G KLG++ + +E D+ Sbjct: 154 IGEPTAMLFKAFYLNICCCKCFIKRKCPEEKAVEESIREQQRQQSSWTTADESGKMPPAKVKDLVVVEEDDEEDDEEEDIVNIPISVTILLLILYILLGAAVFRIWEK-WTLIEGTYFSFITLSTIGFGDYVPGKDGPFNSMTVITELLVGALYCFFGLTVLSMCINLIQDEISAKFHWIGLKLGMVKRVEQPSDDESEDE 353 HSP 3 Score: 68.5514 bits (166), Expect = 2.317e-8 Identity = 29/60 (48.33%), Postives = 43/60 (71.67%), Query Frame = 3 Query: 294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRI 473 C + + S +GTF++VI Y++MGGFLF+YLE NE+ C+ KY+KY +K NE++ RI Sbjct: 84 CCKRFGSIMLSQLGTFVIVIFYVVMGGFLFQYLEVENEVSSCQTKYDKYLSKRNEAVDRI 143
BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Match: A0A267FFS9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032347g1 PE=3 SV=1) HSP 1 Score: 281.952 bits (720), Expect = 3.114e-85 Identity = 158/347 (45.53%), Postives = 231/347 (66.57%), Query Frame = 3 Query: 294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINE--GNHPDYEIED------------DENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLI 1289 C + + S +GTF++VI Y++MGGFLF+YLE NE+ C+ KY+KY +K NE++ RI ++ + + + + ++ F+KD++ ++ +P NCST+GQ N+ WN N+ +FCVT+ITTIGYG+I P T WG+I MIY+I GIPLMLLFLT +GE A F+ YLN+CCC+CFI R+ + E + Q + G P +++D +E V IPI+V +++L +YI++GA +FRIWE+ W++++GTYFS+ITL+TIGFGD+VPGKDG F TEL+VG +YC GL +LSMC+NLIQDEI++KF W+G KLG++ Sbjct: 84 CCKRFGSIMLSQLGTFVIVIFYVVMGGFLFQYLEVENEVSSCQTKYDKYLSKRNEAVDRIYNMAQNGKNAVAAKASIFTEISDFAKDIYTLSMDPRLNCSTLGQGDNIPYWNFANAAYFCVTVITTIGYGHIAPGTSWGQIVCMIYAILGIPLMLLFLTKIGEPTAMLFKAFYLNICCCKCFIKRKCPEEKAVEESIREQQRQQSSWTTADESGKMPPAKVKDLVVVEEDDEEDDEEEDIVNIPISVTILLLILYILLGAAVFRIWEK-WTLIEGTYFSFITLSTIGFGDYVPGKDGPFNSMTVITELLVGALYCFFGLTVLSMCINLIQDEISAKFHWIGLKLGMV 429
BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Match: A0A267FMF4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022638g1 PE=3 SV=1) HSP 1 Score: 271.166 bits (692), Expect = 1.600e-81 Identity = 161/351 (45.87%), Postives = 240/351 (68.38%), Query Frame = 3 Query: 294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFI------SRRVEIVDSTENDKKLNIE-------GQPPPKINE-GNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSD 1301 C++ + SH+GTFL+V+ Y +MGGFLF+YLE NEI C+ K K+ KL+ES+ +I I+ +Q S ++ + F++D + + +PS NC+T+ ++ WN+ N+ +FCVTIITTIGYG+I+P+T WG+I MIYSI GIPLMLLFL+ +GE A FR YLN+ CC+CF+ ++ +E + + + + + +PP K+ + + E E++E+ V IPITV +I+L +YI++GA +F +WE+EW++V+GTYFS+ITL+TIGFGD+VPG+DG F + TEL+VG +YCL GLA+LSMC+NLIQDEI +KF+WLG K+G+I + Sbjct: 72 CMKRFSSIMLSHLGTFLIVVLYTLMGGFLFQYLEVENEISGCQTKSEKFIAKLDESVDQIYNIAQGTNA-TQAKSAIQEELNQFAQDTYTLGVDPSMNCTTLKTGESMPSWNVANAAYFCVTIITTIGYGHISPVTQWGQIVCMIYSILGIPLMLLFLSKIGEPTAMLFRSFYLNIFCCKCFVKKLPNENKLMEAMQENGGNAQTSWQQVEEGDGKRPPAKVTVIEDDVEEEEENEEDDVVNIPITVTIILLILYILMGAAVFMVWEKEWTLVEGTYFSFITLSTIGFGDYVPGRDGPFNDIQVITELLVGCIYCLFGLAMLSMCINLIQDEIQAKFQWLGRKIGMIKKAQ 421
BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Match: A0A267FK89 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018280g2 PE=3 SV=1) HSP 1 Score: 270.781 bits (691), Expect = 2.251e-81 Identity = 161/350 (46.00%), Postives = 240/350 (68.57%), Query Frame = 3 Query: 294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFI------SRRVEIVDSTENDKKLNIE-------GQPPPKINE-GNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDG-FEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDS 1298 C++ + SH+GTFL+V+ Y +MGGFLF+YLE NEI C+ K K+ KL+ES+ +I I+ +Q S ++ + F++D + + +PS NC+T+ ++ WN+ N+ +FCVTIITTIGYG+I+P+T WG+I MIYSI GIPLMLLFL+ +GE A FR YLN+ CC+CF+ ++ +E + + + + + +PP K+ + + E E++E+ V IPITV +I+L +YI++GA +F +WE+EW++V+GTYFS+ITL+TIGFGD+VPG+DG F + TEL+VG +YCL GLA+LSMC+NLIQDEI +KF+WLG K+G+I + Sbjct: 72 CMKRFSSIMLSHLGTFLIVVLYTLMGGFLFQYLEVENEISGCQTKSEKFIAKLDESVDQIYNIAQGTNA-TQAKSAIQEELNQFAQDTYTLGVDPSMNCTTLKTGESMPSWNVANAAYFCVTIITTIGYGHISPVTQWGQIVCMIYSILGIPLMLLFLSKIGEPTAMLFRSFYLNIFCCKCFVKKLPNENKLMEAMQENGGNAQTSWQQVEEGDGKRPPAKVTVIEDDVEEEEENEEDDVVNIPITVTIILLILYILMGAAVFMVWEKEWTLVEGTYFSFITLSTIGFGDYVPGRDGPFNDIQVITELLVGCIYCLFGLAMLSMCINLIQDEIQAKFQWLGRKIGMIKKA 420
BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Match: kcnk15 (potassium channel subfamily K member 15-like [Source:NCBI gene;Acc:103042097]) HSP 1 Score: 73.9442 bits (180), Expect = 8.167e-14 Identity = 66/205 (32.20%), Postives = 93/205 (45.37%), Query Frame = 3 Query: 621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235 QW S +F +T+ITTIGYG+ P TD GK+ M Y++ GIPL L+ ++GE M TF RF+ C F RR E+ S EN + + + VGA F +E W+ Y+ +ITL TIGFGDFV + + E ++ MY L+GL ++ LNL+ Sbjct: 77 QWKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFLLHRTKQCLGF--RRTEV--SMENMVLIGF----------------------------------LSCLGTLCVGAAAFSHFEG-WTFFHAYYYCFITLTTIGFGDFVALQKNEDLQEKTPYVVFSFMYILVGLTVIGAFLNLV 242
BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Match: ENSAMXT00000047723.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:15897283:15919205:1 gene:ENSAMXG00000033807.1 transcript:ENSAMXT00000047723.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 63.929 bits (154), Expect = 1.553e-10 Identity = 56/178 (31.46%), Postives = 89/178 (50.00%), Query Frame = 3 Query: 327 HIGTFLMVITYIIMGGFLFKYLE---ENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNL-CCCRCFISR 848 H L +I Y ++G LF +E N+ L E + K+ ++E + STS + ++ LE ++ FK + S + +W+ Y S+FFC T+ TT+GYG I P+T G++ ++Y+ GIPLMLL +T+VG+I+A F Y L CR + R Sbjct: 139 HAALILSLIVYALLGAALFHAIEGTQSNDGTLEIHEGFRKF---VHEVVNEARNKSTSANVSEEV---LEAVGEKILRE-FKAVWMQSSD-----------RWHFYGSLFFCCTVFTTVGYGEIYPVTKAGRVACILYATVGIPLMLLVITDVGDILAVLFSNSYRRLHSSCRRLLYR 298 HSP 2 Score: 48.9062 bits (115), Expect = 8.382e-6 Identity = 25/68 (36.76%), Postives = 36/68 (52.94%), Query Frame = 3 Query: 1029 ACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNL 1232 A + IWE + D YF +ITL TIGFGD VP F ++ ++ ++G+AI+SM L Sbjct: 425 ALILPIWEDDLGKFDAFYFCFITLTTIGFGDIVPKHPKF--------FMLTFLFIIMGMAIMSMAFKL 484
BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Match: kcnk9 (potassium two pore domain channel subfamily K member 9 [Source:NCBI gene;Acc:103047047]) HSP 1 Score: 63.5438 bits (153), Expect = 1.944e-10 Identity = 63/205 (30.73%), Postives = 88/205 (42.93%), Query Frame = 3 Query: 621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235 QW S +F +T+ITTIGYG+ P TD GK M Y++ GIPL L+ ++GE M TF + YL +C R E+ S EN + + +GA F +E +WS Y+ +ITL TIGFGDFV + + MY L+GL ++ LNL+ Sbjct: 132 QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVK--YLLKRIKKCCGMRITEV--SMENMVTVGF----------------------------------FSCMGTLCIGAAAFSHYE-DWSFFQSYYYCFITLTTIGFGDFVALQKNRALQRKPLYVAFSFMYILVGLTVIGAFLNLV 297
BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Match: kcnk1a (potassium channel subfamily K member 1-like [Source:NCBI gene;Acc:103029028]) HSP 1 Score: 62.3882 bits (150), Expect = 3.185e-10 Identity = 71/279 (25.45%), Postives = 124/279 (44.44%), Query Frame = 3 Query: 624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGL-AILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELAD-----DVEPFSYSTSQPQENQMKIMQTNFIENGSPQMLIKQTD 1442 W+ +++FF T+++T GYG+ PL+D GK ++YS+ GIP LLFLT + +R+ + + + + G H + LIV+ + ++ A +F + E+EW+ ++ YF +I+L+TIG GD+VPG +G+ + + +Y LLGL A+L + + + K R + YL KE D D + FS+++ ++ +T+ I + SP I TD Sbjct: 102 WDFTSALFFASTVLSTTGYGHTVPLSDEGKAFCILYSVVGIPFTLLFLTA----------------------VVQRIMVFSTRRPVAYVQRRWALSKPLVSGVHAG---------------LMALIVVSCFFLIPAIIFSVMEEEWNFLESFYFCFISLSTIGLGDYVPG-EGYNQKFRQLYKVGITVYLLLGLIAMLVVLETFCELQQLKKLRKMF----------YLKKEITEDQLNIVDHDHFSFASVSDPVASVRDYRTDLINDSSP---IAATD 329
BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Match: kcnk1a (potassium channel subfamily K member 1-like [Source:NCBI gene;Acc:103029028]) HSP 1 Score: 58.5362 bits (140), Expect = 5.810e-9 Identity = 53/201 (26.37%), Postives = 94/201 (46.77%), Query Frame = 3 Query: 624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCL 1226 W+ +++FF T+++T GYG+ PL+D GK ++YS+ GIP LLFLT + +R+ + + + + G H + LIV+ + ++ A +F + E+EW+ ++ YF +I+L+TIG GD+VPG +G+ + + +Y LLGL + + L Sbjct: 102 WDFTSALFFASTVLSTTGYGHTVPLSDEGKAFCILYSVVGIPFTLLFLTA----------------------VVQRIMVFSTRRPVAYVQRRWALSKPLVSGVHAG---------------LMALIVVSCFFLIPAIIFSVMEEEWNFLESFYFCFISLSTIGLGDYVPG-EGYNQKFRQLYKVGITVYLLLGLIAMLVVL 264
BLAST of Potassium channel subfamily K 8 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003416.1 (pep scaffold:Pmarinus_7.0:GL476517:78247:80718:1 gene:ENSPMAG00000003129.1 transcript:ENSPMAT00000003416.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 76.6406 bits (187), Expect = 3.407e-16 Identity = 73/208 (35.10%), Postives = 104/208 (50.00%), Query Frame = 3 Query: 621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLN-----LCCCRC--------------FISRRVEIVDSTEN---DKKLNIEGQPPPKINEGNH-----------PDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGF 1145 +WN S+FFC TI TTIGYG+I P TD GKI M+Y+ FGIP+MLL L +VG+++A IY + L RC R +I DS + D +++ + P EG D D E + +P T++ +++F+Y++ G L WE EWS +D YF ++T+ TIG GD VP F Sbjct: 1 KWNFLGSLFFCCTIFTTIGYGHIAPSTDGGKIMCMVYATFGIPIMLLVLADVGDLLARTLTTIYTSFRHRLLPGARCGRQHPPGDGPEGNDLQRSRTKIDDSHRHEGEDDAVDVPLKSPGSDVEGGRELPATVSIAEGADVPEADREVKELDVPFTLIFLIVFVYLMFGTFLLPCWE-EWSYLDAFYFVFVTMTTIGLGDIVPKHPNF 207
BLAST of Potassium channel subfamily K 8 vs. Ensembl Nematostella
Match: EDO43464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYH6]) HSP 1 Score: 62.3882 bits (150), Expect = 1.372e-10 Identity = 73/271 (26.94%), Postives = 122/271 (45.02%), Query Frame = 3 Query: 357 YIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIED--------DENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGF 1145 Y+ +GG +F LE + + K +K ++ ++R + S +N +S L++ + + D+ + SK + QWNI NSI+FC+T+ TTIGYG++ P+T G++ +IY++ GIPL L L VG+I+ Y+N C K +PDYE E+ D + + + ++++ +F I G C W + W YF ++T TIGFGD VP + + Sbjct: 68 YLAIGGIIFMSLERSPK---AKIDTSKDLIEIFSVLKRSYIGNLSFPDN---VSSLDMVGNLTTADLHRFEKLLSKIHVSRALSAK-PQWNILNSIYFCMTVTTTIGYGSLAPVTVPGRVICVIYALLGIPLTLALLAVVGKIVGD-----YINDTCALVL-------------------------KWFRHLYPDYEYENMNQNQELGDGQIDAPLWLGLLILFIFTTITAGLC---CWMEGWDFGTSFYFQFVTYLTIGFGDVVPTSEKY 298
BLAST of Potassium channel subfamily K 8 vs. Ensembl Nematostella
Match: EDO33193 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSX6]) HSP 1 Score: 59.6918 bits (143), Expect = 5.108e-10 Identity = 60/208 (28.85%), Postives = 97/208 (46.63%), Query Frame = 3 Query: 606 PGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLN 1229 NL QW+ S++F T+ITTIGYG+ P T GKI MIY+ GIPL L ++GE TF L C + RR++ +KL ++ D + + + L+ + I + GA +F +E+ W Y+ +IT+ TIGFGD+V +D ++ + + + ++ GL I+ +N Sbjct: 73 KANLYQWSFAGSVYFATTVITTIGYGHTVPRTPRGKIFCMIYAAVGIPLALTMFQSIGERFNTF-------LAC----MFRRLK--------RKLGMKA-----------------TDVSSTTNLVVVCGLLAMVITVSSGAFIFTHYEK-WDYFHSLYYCFITVTTIGFGDYVALQDSKDERYSNKYVGISLLFIFFGLTIVGSVMN 243
BLAST of Potassium channel subfamily K 8 vs. Ensembl Nematostella
Match: EDO46328 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQB1]) HSP 1 Score: 58.9214 bits (141), Expect = 6.997e-10 Identity = 69/265 (26.04%), Postives = 120/265 (45.28%), Query Frame = 3 Query: 342 LMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGK 1136 +++ Y++ G +F+ LE NE NK LN + ++ ++ N I+ F V K+ C + +++W+ Y S++F +++TTIGYG++ P T G+I MI+++FGIPL L+ L N+G+ + +++ ++ RV + EG P +E+ L +F +++GA L+ E W+ DG YF +IT +TIGFGD VP + Sbjct: 29 ILLGVYLLSGAAVFQVLENENE--------NKDVVNLNS-----LRMTFCKKYN--------ISTEDFELLVGKVERATKYRCGGPPESWCMSRWSYYASLYFTWSVVTTIGYGHLAPSTLGGRIFCMIFALFGIPLNLMILKNLGDRIKDVIHYVHF-------LLATRV-----------MKREGDP-----------HEVA---------LCFSALGFMFAMLVIGAILYAQTEH-WNYFDGIYFCFITFSTIGFGDLVPNQ 233
BLAST of Potassium channel subfamily K 8 vs. Ensembl Nematostella
Match: EDO47668 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLC5]) HSP 1 Score: 47.3654 bits (111), Expect = 6.650e-6 Identity = 44/146 (30.14%), Postives = 78/146 (53.42%), Query Frame = 3 Query: 351 ITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRI-MAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGN-LAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGE 782 I Y++MG +F++LE +E K ++ + IQRI + SR+E + + + + ++ G + L +W+ S+FF T+ITTIGYG+++P T +G+I M+Y++FGIP+ L LT++G+ Sbjct: 20 ILYLVMGMVVFRFLESGHE--------KKEREQVQKDIQRIRHKFNISRKEMKEFV-------------------DVVQKAASFGLTQDWLEKWSYTGSLFFSGTVITTIGYGHLSPETFFGRIFCMLYALFGIPITWLMLTSLGK 138
BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Match: kcnk3a (potassium two pore domain channel subfamily K member 3 [Source:NCBI gene;Acc:101167669]) HSP 1 Score: 74.7146 bits (182), Expect = 3.990e-14 Identity = 80/299 (26.76%), Postives = 128/299 (42.81%), Query Frame = 3 Query: 342 LMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLA-QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235 L +TY+I+G +F LE E K+ + E ++ +STS ++E +N + +P QWN S +F +T+ITTIGYG+ P TD GK+ M+Y++ GIPL L+ ++GE + TF R++ +L +C RR E+ + + I G L+ + GA F +E W+ Y+ +ITL TIGFGD+V + G E ++ +Y L+GL ++ LNL+ Sbjct: 13 LCTLTYLIVGAAIFDALESKKETSQSKDLRAR-----KEDLRHRFNLSTS-------------------------DFEKLENVVLLLKPHKAGLQWNFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMLYALLGIPLTLVMFQSLGERINTFVRYLLHHL--KKCLGMRRTEV-----SMVNMVIVG-------------------------------LVSCMTTLCAGALAFSHFEG-WTFFQAYYYCFITLTTIGFGDYVALQKGEALQEKQGYVVFCFIYILMGLGVIGAFLNLV 242
BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Match: kcnk15 (potassium channel subfamily K member 15 [Source:NCBI gene;Acc:101160319]) HSP 1 Score: 72.0182 bits (175), Expect = 3.476e-13 Identity = 65/205 (31.71%), Postives = 93/205 (45.37%), Query Frame = 3 Query: 621 QWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLI 1235 QW S +F +T+ITTIGYG+ P TD GK+ M Y++ GIPL L+ ++GE M TF F+ + +C RR E+ S EN + + + + VGA F +E WS Y+ +ITL TIGFGDFV + + E + MY L+GL ++ LNL+ Sbjct: 82 QWKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVHFLLHKV--KQCLGCRRTEV--SMENMVLVGL----------------------------------LSCVGTLCVGAAAFSHFEG-WSFFHAYYYCFITLTTIGFGDFVALQKKEDLQEKTPYVAFSFMYILVGLTVIGAFLNLV 247
BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Match: kcnk1b (potassium two pore domain channel subfamily K member 1 [Source:NCBI gene;Acc:101174617]) HSP 1 Score: 59.6918 bits (143), Expect = 1.991e-9 Identity = 57/203 (28.08%), Postives = 97/203 (47.78%), Query Frame = 3 Query: 624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGM--YCLLGLAILSMCL 1226 W+ +++FF T+++T GYG+ PL+D GK +IYS+ GIP LLFLT V + + F +RR + T G P + +V + ++ + + ++ A +F E+ W+ ++ YF +I+L+TIG GD+VPG+ +K EL G+ Y +LGL ++ + L Sbjct: 102 WDFTSALFFASTVLSTTGYGHTAPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRIMV--------------FTTRRPVVYIHTR-------WGLSKPLV----------------AIVHATLLAMLAVSCFFLIPAAIFSALEENWNFLESFYFCFISLSTIGLGDYVPGEAANQKFR---ELYKVGITVYLILGLIVMLVVL 264
BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Match: kcnk1b (potassium two pore domain channel subfamily K member 1 [Source:NCBI gene;Acc:101174617]) HSP 1 Score: 59.6918 bits (143), Expect = 2.287e-9 Identity = 57/203 (28.08%), Postives = 97/203 (47.78%), Query Frame = 3 Query: 624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGM--YCLLGLAILSMCL 1226 W+ +++FF T+++T GYG+ PL+D GK +IYS+ GIP LLFLT V + + F +RR + T G P + +V + ++ + + ++ A +F E+ W+ ++ YF +I+L+TIG GD+VPG+ +K EL G+ Y +LGL ++ + L Sbjct: 102 WDFTSALFFASTVLSTTGYGHTAPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRIMV--------------FTTRRPVVYIHTR-------WGLSKPLV----------------AIVHATLLAMLAVSCFFLIPAAIFSALEENWNFLESFYFCFISLSTIGLGDYVPGEAANQKFR---ELYKVGITVYLILGLIVMLVVL 264
BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Match: kcnk18 (potassium two pore domain channel subfamily K member 18 [Source:NCBI gene;Acc:101159039]) HSP 1 Score: 58.151 bits (139), Expect = 9.096e-9 Identity = 47/175 (26.86%), Postives = 88/175 (50.29%), Query Frame = 3 Query: 294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLN 818 CL +V F H+ ++ Y ++G +F+ +E N+ +E Y ++ ++ + ++ ++ Q S ++ ++E M F+ F+ N W + S+FFC T+ TT+GYG I P+T GK+ ++Y++ GIPLMLL + +VG+ +A Y+ Sbjct: 10 CLAPLWRV-FPHLALCGTLVAYAVLGALIFQRIEGGNKPSKIQEDYREFLGEIVDIVRNHSQNTSCSQ--SCMVDQVEKKMKTFNSIWFQ----------------NPDNWTFFGSMFFCCTVFTTVGYGEIYPVTLSGKVVCVLYAMVGIPLMLLVILDVGDFLALLMTKAYVQ 165 HSP 2 Score: 52.373 bits (124), Expect = 5.610e-7 Identity = 25/79 (31.65%), Postives = 44/79 (55.70%), Query Frame = 3 Query: 1026 GACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262 G + +WE++++ D YF +ITL TIGFGD +P + ++ ++ ++G+AI+SM L Q I + +R Sbjct: 305 GGLILPLWEKDFTDFDPYYFCFITLTTIGFGDIIPKHPNY--------FMLISLFIIVGMAIMSMAFKLSQTRIVTCYR 375
BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Match: SMESG000024430.1 (SMESG000024430.1) HSP 1 Score: 718.383 bits (1853), Expect = 0.000e+0 Identity = 385/385 (100.00%), Postives = 385/385 (100.00%), Query Frame = 3 Query: 291 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADDVEPFSYSTSQPQENQMKIMQTNFIENGSPQMLIKQTDC 1445 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVTIITTIGYGNITPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENVFVVIPITVVLIVLFIYIIVGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADDVEPFSYSTSQPQENQMKIMQTNFIENGSPQMLIKQTDC Sbjct: 15 TCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVTIITTIGYGNITPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRVEIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENVFVVIPITVVLIVLFIYIIVGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKEELADDVEPFSYSTSQPQENQMKIMQTNFIENGSPQMLIKQTDC 399
BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Match: SMESG000016405.1 (SMESG000016405.1) HSP 1 Score: 272.707 bits (696), Expect = 1.547e-86 Identity = 172/381 (45.14%), Postives = 240/381 (62.99%), Query Frame = 3 Query: 321 FSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIMAISTSRQENSQIMSELEITMTMFSKDVFKINYEPSKNCSTIGQPGNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFI-------------SRR--VEIVD-STENDKKLN---IEGQPPPK-INEGNHPDY-EIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKE-ELADDVEPFSYSTSQPQENQMKIMQTN 1397 SH GT ++I Y+I GGFLF LE+ NE C Y KLN++ R ++I S + ++ + FSK+V+ + + PSK+C+TIGQP NL+ WN+ NSIFFC TIITTIGYGNI P T WG+I +IY+ GIPLMLLFL+N GE++A+ FRF+Y NLCCCRCF+ S+R +EI + EN + LN ++ PPPK I+E Y + E+D++ + IP+TVV+ L IY+ +GA +F+IWE W +V YFS+IT++TIGFGD P K+ + ELIVG +YC++GLAILSMCLNL+++EI KF WLGNKLG++ + +E E +D + S + + Q +M N Sbjct: 17 LSHFGTLFIIILYLIGGGFLFALLEQENEKSSCFTSYKLLMDKLNDTTYRGVSIGNSGYNATIYYQQMYSMLFNFSKEVYTLGFSPSKDCTTIGQPDNLSAWNLANSIFFCATIITTIGYGNIVPSTVWGRIVCIIYAFIGIPLMLLFLSNFGEVLASAFRFVYTNLCCCRCFVKGKYTSISEFESMSKRSAIEIKNFELENAENLNSNPVKATPPPKFIDEDLDIVYVDDENDQDEIINIPLTVVIGFLIIYMFLGALIFQIWET-WDLVAAVYFSFITVSTIGFGDLYPAKNTIGSSVATLELIVGAVYCIIGLAILSMCLNLVKEEIVEKFSWLGNKLGIVKSNTGSSEECEEVNDHQSNSRIIIENSDFQNSVMHVN 396
BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Match: SMESG000016405.1 (SMESG000016405.1) HSP 1 Score: 116.701 bits (291), Expect = 4.998e-30 Identity = 74/171 (43.27%), Postives = 109/171 (63.74%), Query Frame = 3 Query: 894 IEGQPPPK-INEGNHPDY-EIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLIDDSDYLDKE-ELADDVEPFSYSTSQPQENQMKIMQTN 1397 ++ PPPK I+E Y + E+D++ + IP+TVV+ L IY+ +GA +F+IWE W +V YFS+IT++TIGFGD P K+ + ELIVG +YC++GLAILSMCLNL+++EI KF WLGNKLG++ + +E E +D + S + + Q +M N Sbjct: 23 VKATPPPKFIDEDLDIVYVDDENDQDEIINIPLTVVIGFLIIYMFLGALIFQIWET-WDLVAAVYFSFITVSTIGFGDLYPAKNTIGSSVATLELIVGAVYCIIGLAILSMCLNLVKEEIVEKFSWLGNKLGIVKSNTGSSEECEEVNDHQSNSRIIIENSDFQNSVMHVN 192
BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Match: SMESG000031911.1 (SMESG000031911.1) HSP 1 Score: 105.145 bits (261), Expect = 9.583e-24 Identity = 93/262 (35.50%), Postives = 143/262 (54.58%), Query Frame = 3 Query: 609 GNLAQWNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRV------EIVDSTENDKK----------LNIEGQPPPKINE------------------GNHPDYEIEDDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGK-DGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLI 1289 GN+ W ++ + +TIITTIGYG+I P T G+ +++Y+I GIPLMLL LTN+G++MA F+F+Y C + +I R +++DS N +K +NI + P I + GN + + + V +PI + L +L +YI+VGA +F W+ W+ + YF +ITL TIGFGD VPG + EK++ T+ I Y + GLA+ +MC LIQ+++ F LG ++GLI Sbjct: 356 GNIL-WTFSGALLYSITIITTIGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKEITTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDG-WTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI 614 HSP 2 Score: 50.0618 bits (118), Expect = 3.296e-6 Identity = 28/70 (40.00%), Postives = 42/70 (60.00%), Query Frame = 3 Query: 294 CLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIM-AISTSRQE 500 C + S+ FS IG +V+ YII GGFLF+ LE NEI + K + +N+S++++M I +S QE Sbjct: 123 CCKQSIAFFFSQIGVMCIVVAYIIAGGFLFQNLEAKNEINISKSG----ESNINDSLKKLMEKIRSSEQE 188
BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Match: SMESG000013544.1 (SMESG000013544.1) HSP 1 Score: 85.5001 bits (210), Expect = 2.533e-17 Identity = 83/248 (33.47%), Postives = 132/248 (53.23%), Query Frame = 3 Query: 624 WNIYNSIFFCVXXXXXXXXXXXXPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFI-----------------SRRVEIVDSTEN-DKKLNIEGQPPPKINEGNH----------------PDYEIE-DDENXXXXXXXXXXXXXXXXXXXXGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGKDGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFR 1262 W SI +C+T+ITTIGYG+ITP T G+ ++IY+IFGIP+ML+ L ++G +MA FR IY + C + F S E++D +++ D ++++ P GN+ P+ +E ++ V +P+++V+ V IY +VG+ F I E W + D YFS+ITL+TIGFGDFVP G E + + I+ Y L GL++ M +L++ + S + Sbjct: 426 WTFGGSILYCITVITTIGYGHITPKTIPGRFGTIIYAIFGIPIMLICLAHIGSLMANMFRLIY-RVSCLKAFKKYKKSQKSKCQNSEKQSSTSNELLDKSDDEDNQISLTVVKNPHNPTGNYFGSTVQFRKILFHIPNPNRLLEAAKKSKSVEVPVSLVITVFIIYNLVGSVFFTICEG-WKITDSFYFSFITLSTIGFGDFVPVAIGNEAEQYKS--IMCSFYVLFGLSLCVMSFDLMEKKCKSTIK 669 The following BLAST results are available for this feature:
BLAST of Potassium channel subfamily K 8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Potassium channel subfamily K 8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Potassium channel subfamily K 8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Potassium channel subfamily K 8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Potassium channel subfamily K 8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Potassium channel subfamily K 8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Potassium channel subfamily K 8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Potassium channel subfamily K 8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Potassium channel subfamily K 8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Potassium channel subfamily K 8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Potassium channel subfamily K 8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Potassium channel subfamily K 8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Potassium channel subfamily K 8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Potassium channel subfamily K 8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30007122 ID=SMED30007122|Name=Potassium channel subfamily K 8|organism=Schmidtea mediterranea sexual|type=transcript|length=1506bpback to top protein sequence of SMED30007122-orf-1 >SMED30007122-orf-1 ID=SMED30007122-orf-1|Name=SMED30007122-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=400bp MDNNEKENNKQKWKTCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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