DDE superfamily endonuclease CENP B

Overview
NameDDE superfamily endonuclease CENP B
Smed IDSMED30007093
Length (bp)2903
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of DDE superfamily endonuclease CENP B (SMED30007093) t-SNE clustered cells

Violin plots show distribution of expression levels for DDE superfamily endonuclease CENP B (SMED30007093) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DDE superfamily endonuclease CENP B (SMED30007093) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DDE superfamily endonuclease CENP B (SMED30007093) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30007093

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30007093h1SMcG0001254 SmedASXL_012406SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30007093h1SMcG0001254 SmedASXL_012406SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30007093h1SMcG0001254 dd_Smed_v4_11391_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30007093h1SMcG0001254 dd_Smed_v4_11391_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30007093h1SMcG0001254 dd_Smed_v4_11391_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Zebrafish
Match: si:rp71-1d10.8 (si:rp71-1d10.8 [Source:ZFIN;Acc:ZDB-GENE-141216-274])

HSP 1 Score: 53.9138 bits (128), Expect = 1.270e-6
Identity = 57/237 (24.05%), Postives = 96/237 (40.51%), Query Frame = 1 
Query:  520 FMLFLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNKPDHIWMTDEVSIACDNSNVPKIL-----------PITIQRPQSNTYWNPTAAVLGAGNAAGDKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFRPLIPQ---RPVILLYDGHLQFV-TVRVLEKAKEDNVLLFPLPPHPPYNHCVESSCFAAYPKYFTKRIQKYHDDFK 1185
            F  F+ R P L+  +  P +   +  ++ + + +++     +L    IK+ P HIW        CD S +  I            P      +  T     +AVL A NA G   P  ++FK S +  E +  S++      S +GW+ AD F  W E  F   +P+   RP +LL D   + V  +  L    ++NV +   P     +  +  S    + +  T +    H+D K
Sbjct:  233 FEGFMKRNPGLQ--IKKPEAISPATTMNEKELSSWFRMYKDILDALGIKDIPSHIW-------KCDLSELQDIFLSEQYVNEGEDPCFQINTEGET--EEVSAVLAAFNACGTFAP-LIIFKGSMVRNEWLSASLENMCMRASESGWITADMFNDWGET-FVAQLPKDDTRPHLLLLDDQSRHVFNLSFLSIMNQNNVEVICYPALQQSSQALFQSLKHNWCEAITDQWHPQHEDMK 456

HSP 2 Score: 51.2174 bits (121), Expect = 6.845e-6
Identity = 56/237 (23.63%), Postives = 96/237 (40.51%), Query Frame = 1 
Query:  520 FMLFLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNKPDHIWMTDEVSIACDNSNVPKIL-----------PITIQRPQSNTYWNPTAAVLGAGNAAGDKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFRPLIPQ---RPVILLYDGHLQFV-TVRVLEKAKEDNVLLFPLPPHPPYNHCVESSCFAAYPKYFTKRIQKYHDDFK 1185
            F  F+ R P L+  +  P +   +  ++ + + +++      L    IK+ P HIW        CD S +  I            P      +  T     +A+L A NA G   P  ++FK S +  E +  S++      S +GW+ AD F +W E  F   +P+   RP +LL D   + V  +  L    ++NV +   P     +  +  S    + +  T +    H+D K
Sbjct: 1149 FEGFMKRNPGLQ--IKKPEAISPATTMNEKELSSWFRMYKVTLDALGIKDIPSHIW-------KCDLSELQDIFLSEQYVNEGEDPCFQINTEGET--EEISALLAAFNACGTFAP-LIIFKGSMVRNEWLSASLENMCMRASESGWITADMFNEWGE-MFVAQLPKDDTRPHLLLLDDQSRHVFNLSFLSLMNQNNVEVICYPALQQSSQALFQSLKHNWCEAITNQWHPQHEDMK 1372

HSP 3 Score: 50.8322 bits (120), Expect = 8.975e-6
Identity = 48/184 (26.09%), Postives = 76/184 (41.30%), Query Frame = 1 
Query:  520 FMLFLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNKPDHIWMTDEVSIACDNSNVPKIL-----------PITIQRPQSNTYWNPTAAVLGAGNAAGDKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFRPLIPQ---RPVILLYDGHLQFV 1029
            F  F+ R P L+  +  P +   +  ++ + + +++      L    IK+ P HIW        CD S +  I            P      +  T     +AVL A NA G   P  ++FK S +  E +  S++      S +GW+ AD F  W E  F   +P+   RP +LL D   + V
Sbjct:  691 FEGFMKRNPGLQ--IKKPEAISPATTMNEKELSSWFRMYKATLDALGIKDIPSHIW-------KCDLSELQDIFLSEQYVNEGEDPCFQINTEGET--EEVSAVLAAFNACGTFAP-LIIFKGSMVRNEWLSASLENMCMRASESGWITADMFNDWGET-FVAQLPKDDTRPHLLLLDDQSRHV 861
[Close]
BLAST of DDE superfamily endonuclease CENP B vs. TrEMBL
Match: A0A0R3TSG7 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS10582 PE=4 SV=1)

HSP 1 Score: 385.956 bits (990), Expect = 1.590e-166
Identity = 165/271 (60.89%), Postives = 223/271 (82.29%), Query Frame = 1 
Query:  520 FMLFLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNKPDHIWMTDEVSIACDNSNVPKILPITIQRPQSNTYWNPTAAVLGAGNAAGDKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFRPLIPQRPVILLYDGHLQFVTVRVLEKAKEDNVLLFPLPPHPPYNHCVESSCFAAYPKYFTKRIQKYHDDFKRN-VNKTNVSRIICQAYEWALQPINLIQTFFKLGICPYNNLSNSLAPYM 1329
            F  FLNRWPDLKN+L+GPRSNRKSKGVS ++IQAY+E LDKVL KYDIK+KP+H+W+ DEVS++C+N   PK+LPI++QR QS +YW+PT  ++GAG+AAG+KIP FL++    I+  MMEGSV+G+KFA++ +GWVN+DAFIQW+ +HFRP I +RP+ILLYDGHLQF++VRVLE+A+ED VLLFPLPPHP YNHC+E++CF A+  YF KR+++++  F  + ++K N++ I+  AYE ALQ  N+I  F +LGICP+NNLS S+  Y+
Sbjct:  192 FYAFLNRWPDLKNFLFGPRSNRKSKGVSGDAIQAYFEQLDKVLTKYDIKDKPEHMWVVDEVSVSCEN-QPPKLLPISVQRAQSVSYWSPTVVIIGAGSAAGEKIPPFLLYHGETITHSMMEGSVRGTKFASTPSGWVNSDAFIQWFLKHFRPQIAKRPLILLYDGHLQFISVRVLERAREDGVLLFPLPPHPAYNHCIENTCFHAFNSYFDKRLERFYQRFPNDPISKQNIAPILTHAYERALQARNMINLFARLGICPFNNLSTSIGAYL 461

HSP 2 Score: 233.032 bits (593), Expect = 1.590e-166
Identity = 106/121 (87.60%), Postives = 116/121 (95.87%), Query Frame = 3 
Query:  171 KPKTRRRRWTQKDMTNAFNAVKCTGMSLRGAASHYNVPESTLRDRVHGRVSLDCSRPGPPTFFTFEEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVDRIAPFKFLNPSQAWFYAFF 533
            +PK+RRRRWTQ+DMTNA+NAVK  GMSLRGAA+ +NVPESTLRDRVHGRVSL+C+RPGPPTFFTF+EEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAV RIAPFK+LNPSQAWFYAF 
Sbjct:   76 RPKSRRRRWTQRDMTNAYNAVKYQGMSLRGAATAFNVPESTLRDRVHGRVSLECNRPGPPTFFTFDEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVGRIAPFKYLNPSQAWFYAFL 196

HSP 3 Score: 62.7734 bits (151), Expect = 4.104e-6
Identity = 23/58 (39.66%), Postives = 35/58 (60.34%), Query Frame = 1 
Query: 2299 CHVCGRIEPPGLSQISEAEEL-VVDWAHCDFCHKWVHLQPCCDSRCVQPDNRFKCIVC 2469
            C +CG++EPPG    ++  EL VVDW  C++C +W+HL   C    +  D+ F C +C
Sbjct:  685 CAICGQLEPPGFDSEADDSELPVVDWITCNYCKRWMHLNSECSRNAILTDSAFMCALC 742
[Close]
BLAST of DDE superfamily endonuclease CENP B vs. TrEMBL
Match: A0A0R3SRV6 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS7952 PE=4 SV=1)

HSP 1 Score: 382.874 bits (982), Expect = 1.492e-165
Identity = 163/271 (60.15%), Postives = 222/271 (81.92%), Query Frame = 1 
Query:  520 FMLFLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNKPDHIWMTDEVSIACDNSNVPKILPITIQRPQSNTYWNPTAAVLGAGNAAGDKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFRPLIPQRPVILLYDGHLQFVTVRVLEKAKEDNVLLFPLPPHPPYNHCVESSCFAAYPKYFTKRIQKYHDDFKRN-VNKTNVSRIICQAYEWALQPINLIQTFFKLGICPYNNLSNSLAPYM 1329
            F  FLNRWPDLKN+L+GPRSNRKSKGVS ++IQAY+E LDKVL KYDIK+KP+H+W+ DEVS++C+N   PK+LPI++QR QS +YW+PT  ++GAG+AAG+KIP FL++    I+  MMEGSV+G+KFA++ +GWVN+DAFIQW+ +HFRP I +RP+ILLYDGHLQF++VRVLE+A+ED VLLFPLPPHP YNHC+E++CF A+  YF KR+++++  F  + ++K N++ I+   YE ALQ  N++  F +LGICP+NNLS S+  Y+
Sbjct:  158 FYAFLNRWPDLKNFLFGPRSNRKSKGVSGDAIQAYFEQLDKVLTKYDIKDKPEHMWVVDEVSVSCEN-QPPKLLPISVQRAQSVSYWSPTVVIIGAGSAAGEKIPPFLLYHGETITHSMMEGSVRGTKFASTPSGWVNSDAFIQWFLKHFRPQIAKRPLILLYDGHLQFISVRVLERAREDGVLLFPLPPHPAYNHCIENTCFHAFNSYFDKRLERFYQRFPNDPISKQNIAPILTHTYERALQARNMVNLFARLGICPFNNLSTSIGAYL 427

HSP 2 Score: 232.646 bits (592), Expect = 1.492e-165
Identity = 106/121 (87.60%), Postives = 116/121 (95.87%), Query Frame = 3 
Query:  171 KPKTRRRRWTQKDMTNAFNAVKCTGMSLRGAASHYNVPESTLRDRVHGRVSLDCSRPGPPTFFTFEEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVDRIAPFKFLNPSQAWFYAFF 533
            +PK+RRRRWTQ+DMTNA+NAVK  GMSLRGAA+ +NVPESTLRDRVHGRVSL+C+RPGPPTFFTF+EEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAV RIAPFK+LNPSQAWFYAF 
Sbjct:   42 RPKSRRRRWTQRDMTNAYNAVKYQGMSLRGAATAFNVPESTLRDRVHGRVSLECNRPGPPTFFTFDEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVGRIAPFKYLNPSQAWFYAFL 162

HSP 3 Score: 62.3882 bits (150), Expect = 4.993e-6
Identity = 23/58 (39.66%), Postives = 35/58 (60.34%), Query Frame = 1 
Query: 2299 CHVCGRIEPPGLSQISEAEEL-VVDWAHCDFCHKWVHLQPCCDSRCVQPDNRFKCIVC 2469
            C +CG++EPPG    ++  EL VVDW  C++C +W+HL   C    +  D+ F C +C
Sbjct:  659 CAICGQLEPPGFDSEADDSELPVVDWITCNYCKRWMHLNSECSRNAILTDSAFMCALC 716
[Close]
BLAST of DDE superfamily endonuclease CENP B vs. TrEMBL
Match: A0A564YDK9 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS5280 PE=4 SV=1)

HSP 1 Score: 382.874 bits (982), Expect = 1.556e-165
Identity = 163/271 (60.15%), Postives = 222/271 (81.92%), Query Frame = 1 
Query:  520 FMLFLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNKPDHIWMTDEVSIACDNSNVPKILPITIQRPQSNTYWNPTAAVLGAGNAAGDKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFRPLIPQRPVILLYDGHLQFVTVRVLEKAKEDNVLLFPLPPHPPYNHCVESSCFAAYPKYFTKRIQKYHDDFKRN-VNKTNVSRIICQAYEWALQPINLIQTFFKLGICPYNNLSNSLAPYM 1329
            F  FLNRWPDLKN+L+GPRSNRKSKGVS ++IQAY+E LDKVL KYDIK+KP+H+W+ DEVS++C+N   PK+LPI++QR QS +YW+PT  ++GAG+AAG+KIP FL++    I+  MMEGSV+G+KFA++ +GWVN+DAFIQW+ +HFRP I +RP+ILLYDGHLQF++VRVLE+A+ED VLLFPLPPHP YNHC+E++CF A+  YF KR+++++  F  + ++K N++ I+   YE ALQ  N++  F +LGICP+NNLS S+  Y+
Sbjct:  159 FYAFLNRWPDLKNFLFGPRSNRKSKGVSGDAIQAYFEQLDKVLTKYDIKDKPEHMWVVDEVSVSCEN-QPPKLLPISVQRAQSVSYWSPTVVIIGAGSAAGEKIPPFLLYHGETITHSMMEGSVRGTKFASTPSGWVNSDAFIQWFLKHFRPQIAKRPLILLYDGHLQFISVRVLERAREDGVLLFPLPPHPAYNHCIENTCFHAFNSYFDKRLERFYQRFPNDPISKQNIAPILTHTYERALQARNMVNLFARLGICPFNNLSTSIGAYL 428

HSP 2 Score: 232.261 bits (591), Expect = 1.556e-165
Identity = 106/121 (87.60%), Postives = 116/121 (95.87%), Query Frame = 3 
Query:  171 KPKTRRRRWTQKDMTNAFNAVKCTGMSLRGAASHYNVPESTLRDRVHGRVSLDCSRPGPPTFFTFEEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVDRIAPFKFLNPSQAWFYAFF 533
            +PK+RRRRWTQ+DMTNA+NAVK  GMSLRGAA+ +NVPESTLRDRVHGRVSL+C+RPGPPTFFTF+EEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAV RIAPFK+LNPSQAWFYAF 
Sbjct:   43 RPKSRRRRWTQRDMTNAYNAVKYQGMSLRGAATAFNVPESTLRDRVHGRVSLECNRPGPPTFFTFDEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVGRIAPFKYLNPSQAWFYAFL 163

HSP 3 Score: 62.3882 bits (150), Expect = 4.870e-6
Identity = 23/58 (39.66%), Postives = 35/58 (60.34%), Query Frame = 1 
Query: 2299 CHVCGRIEPPGLSQISEAEEL-VVDWAHCDFCHKWVHLQPCCDSRCVQPDNRFKCIVC 2469
            C +CG++EPPG    ++  EL VVDW  C++C +W+HL   C    +  D+ F C +C
Sbjct:  660 CAICGQLEPPGFDSEADDSELPVVDWITCNYCKRWMHLNSECSRNAILTDSAFMCALC 717
[Close]
BLAST of DDE superfamily endonuclease CENP B vs. TrEMBL
Match: A0A4E0RTS9 (DDE superfamily endonuclease CENP B OS=Fasciola hepatica OX=6192 GN=D915_008841 PE=4 SV=1)

HSP 1 Score: 373.629 bits (958), Expect = 3.707e-164
Identity = 165/271 (60.89%), Postives = 218/271 (80.44%), Query Frame = 1 
Query:  520 FMLFLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNKPDHIWMTDEVSIACDNSNVPKILPITIQRPQSNTYWNPTAAVLGAGNAAGDKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFRPLIPQRPVILLYDGHLQFVTVRVLEKAKEDNVLLFPLPPHPPYNHCVESSCFAAYPKYFTKRIQKYHDDFKRN-VNKTNVSRIICQAYEWALQPINLIQTFFKLGICPYNNLSNSLAPYM 1329
            F  FLNRWPDLKN+L+GPRSNRKSKGVS +SIQAY+E L+KV+ KY IK+K +H W+ DEVSI+C+N   P+ILPI+IQR QS +YWNPT A+LGA N  G+KIP FL+++ + ++  MMEGSV+G+KF+ S++GWVN+DAFIQW+ +HFR L+  RP++L YDGHLQFV+VRVLE+A+ED+V LFPLPPHP YNHCVE++CF A+  YF KR+ ++ +   R  + +TN S ++  AYE ALQP N+IQ F +LGICP+NNLSN++  YM
Sbjct:  184 FYAFLNRWPDLKNFLFGPRSNRKSKGVSGDSIQAYFEQLEKVINKYGIKDKAEHFWIVDEVSISCEN-QPPRILPISIQRAQSVSYWNPTVAMLGAANGIGEKIPPFLIYRGNNVTPSMMEGSVRGTKFSYSASGWVNSDAFIQWFLKHFRLLVTLRPLVLFYDGHLQFVSVRVLERAREDDVFLFPLPPHPAYNHCVENTCFWAFNVYFKKRVDRFFEQNPRQPLIRTNASPVLTHAYEKALQPSNMIQLFERLGICPFNNLSNAIGAYM 453

HSP 2 Score: 237.269 bits (604), Expect = 3.707e-164
Identity = 113/141 (80.14%), Postives = 126/141 (89.36%), Query Frame = 3 
Query:  120 FQQQVLFIH--DPYVNQA-NKPKTRRRRWTQKDMTNAFNAVKCTGMSLRGAASHYNVPESTLRDRVHGRVSLDCSRPGPPTFFTFEEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVDRIAPFKFLNPSQAWFYAFF 533
            +Q+Q+LF    D    ++  +PKTRRRRWTQ+DMTNA+NAVK  GMSLRGAA+ +NVPESTLRDRVHGRVSL+CSRPGPPTFFT+EEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAV RIAPFK+LNPSQAWFYAF 
Sbjct:   48 YQRQILFYSNFDSVTGRSLQRPKTRRRRWTQRDMTNAYNAVKYQGMSLRGAATAFNVPESTLRDRVHGRVSLECSRPGPPTFFTYEEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVGRIAPFKYLNPSQAWFYAFL 188

HSP 3 Score: 65.855 bits (159), Expect = 4.262e-7
Identity = 32/81 (39.51%), Postives = 47/81 (58.02%), Query Frame = 1 
Query: 2245 MELKSEIDYHPNGEVNQNCHVCGRIEPPG-----LSQISEAEEL-VVDWAHCDFCHKWVHLQPCCDSRCVQPDNRFKCIVC 2469
            +E  +EI+   +GE    C VCG++EPP      ++    A++L VVDW HCD+C++WVH    C    V  +N F C+VC
Sbjct:  688 VECMNEIE---DGEAPDFCVVCGQLEPPESACRPMADGENADDLQVVDWVHCDYCNRWVHWNGSCSKDAVIGNNSFMCVVC 765
[Close]
BLAST of DDE superfamily endonuclease CENP B vs. TrEMBL
Match: A0A5K4F1Q5 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 372.089 bits (954), Expect = 7.459e-164
Identity = 167/274 (60.95%), Postives = 216/274 (78.83%), Query Frame = 1 
Query:  520 FMLFLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNKPDHIWMTDEVSIACDNSNVPKILPITIQRPQSNTYWNPTAAVLGAGNAAGDKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFRPLIPQRPVILLYDGHLQFVTVRVLEKAKEDNVLLFPLPPHPPYNHCVESSCFAAYPKYFTKRIQKYHDDFKRNVN----KTNVSRIICQAYEWALQPINLIQTFFKLGICPYNNLSNSLAPYM 1329
            F  FLNRWPDLKN+L+GPRSNRKSKGVS +SIQ+Y+E L+KVL KY IK+K +H W+ DEVSI+C+N   P+ILPI+IQR QS +YWNPT A+LGA N  G+KIP FL+++   I+  MMEGSV+G+KF+ S++GWVN+DAFIQW+ +HFR L+  RP+IL YDGHLQFV+VRVLE+A+ED V LFPLPPHP YNHCVE++CF A+  YF KR+ ++   F++N N    + N S I+  AYE ALQP N+I  F +LGICP+NNLS+S+  Y+
Sbjct:  170 FYAFLNRWPDLKNFLFGPRSNRKSKGVSGDSIQSYFEQLEKVLNKYGIKDKAEHFWIVDEVSISCEN-QPPRILPISIQRAQSVSYWNPTVAMLGAANGVGEKIPPFLIYRGDGITSSMMEGSVRGTKFSYSASGWVNSDAFIQWFLKHFRVLVSVRPLILFYDGHLQFVSVRVLERAREDGVFLFPLPPHPAYNHCVENTCFWAFQGYFKKRLDRF---FEQNPNQPLLRNNASPILTHAYEKALQPNNMISLFERLGICPFNNLSSSIGAYL 439

HSP 2 Score: 237.654 bits (605), Expect = 7.459e-164
Identity = 117/165 (70.91%), Postives = 134/165 (81.21%), Query Frame = 3 
Query:   72 NDEYWEGNDDDNDSKC--------FQQQVLFIH--DPYVNQA-NKPKTRRRRWTQKDMTNAFNAVKCTGMSLRGAASHYNVPESTLRDRVHGRVSLDCSRPGPPTFFTFEEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVDRIAPFKFLNPSQAWFYAFF 533
            +D+ +EG D ++            + QQ+LF    D    ++  +PKTRRRRWTQ+DMTNA+NAVK  GMSLRGAA+ +NVPESTLRDRVHGRVSL+CSRPGPPTFFT+EEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAV RIAPFK+LNPSQAWFYAF 
Sbjct:   10 SDDAFEGEDKEDTDMLNSAETYNDYHQQILFYRNFDSVSGRSLQRPKTRRRRWTQRDMTNAYNAVKYQGMSLRGAATAFNVPESTLRDRVHGRVSLECSRPGPPTFFTYEEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVGRIAPFKYLNPSQAWFYAFL 174

HSP 3 Score: 78.1814 bits (191), Expect = 6.251e-11
Identity = 39/110 (35.45%), Postives = 58/110 (52.73%), Query Frame = 1 
Query: 2263 IDYHPNGEVNQNCHVCGRIEPPGLS------QISEAEELVVDWAHCDFCHKWVHLQPCCDSRCVQPDNRFKCIVC-------IKQQNDEELEKIMNTEISNEIGATMCIQ 2553
            ID   +GE    C VCG++EPP LS      Q +  +  V+DWAHCD+C++WVHL  CC    V  +N F C+VC       +    + + E ++    S E G +M ++
Sbjct:  653 IDGVEDGEALDFCVVCGQLEPPELSCQPISDQANADDLQVIDWAHCDYCNRWVHLNGCCSEGAVIGNNSFMCVVCRNDSTTTVGNVRNFQQETLLTKNGSGEQGQSMDVK 762
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BLAST of DDE superfamily endonuclease CENP B vs. Planmine SMEST
Match: SMESG000018934.1 (SMESG000018934.1)

HSP 1 Score: 1227.62 bits (3175), Expect = 0.000e+0
Identity = 715/717 (99.72%), Postives = 715/717 (99.72%), Query Frame = 1 
Query:  520 FMLFLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNKPDHIWMTDEVSIACDNSNVPKILPITIQRPQSNTYWNPTAAVLGAGNAAGDKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFRPLIPQRPVILLYDGHLQFVTVRVLEKAKEDNVLLFPLPPHPPYNHCVESSCFAAYPKYFTKRIQKYHDDFKRNVNKTNVSRIICQAYEWALQPINLIQTFFKLGICPYNNLSNSLAPYMPXXXXXXXXXXXXXXXXMTESEFMHNNSNNISMFSGRDPLSNMPLAHSPIIDRSYNPNDNFSIMXXXXXXXXXXXXXXXAPHSLNTSGMYPSLGNIKVLDNMASKAMNQMHTQRAEYNHSKVRASLPVNSICENSQPXXXXXXXXXXXXXXXVLRTTQSQSTPLCKVSPNSSFPVYSIGTSNQIKVVPSEPMQSDXXXXXXXXXXXXXXXXXKIYKSSSHNVTIKPTTSSSTNNRPIIRLQPMPXXXXXXXXXXXXXXXXXXXXLGXXXXXXXXXXXXXXXKTVSTSITTPVVYENQREIEVTELMELKSEIDYHPNGEVNQNCHVCGRIEPPGLSQISEAEELVVDWAHCDFCHKWVHLQPCCDSRCVQPDNRFKCIVCIKQQNDEELEKIMNTEISNEIGATMCIQEDETFYLLNESENPSIEDSVQLISTDNPQNSINTEIDSI 2670
            F  FLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNKPDHIWMTDEVSIACDNSNVPKILPITIQRPQSNTYWNPTAAVLGAGNAAGDKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFRPLIPQRPVILLYDGHLQFVTVRVLEKAKEDNVLLFPLPPHPPYNHCVESSCFAAYPKYFTKRIQKYHDDFKRNVNKTNVSRIICQAYEWALQPINLIQTFFKLGICPYNNLSNSLAPYMPNSSDDDPNDENMDSLDMTESEFMHNNSNNISMFSGRDPLSNMPLAHSPIIDRSYNPNDNFSIMQNNVSQSSFNQNDFFAPHSLNTSGMYPSLGNIKVLDNMASKAMNQMHTQRAEYNHSKVRASLPVNSICENSQPKILSIKNSNASKNSIVLRTTQSQSTPLCKVSPNSSFPVYSIGTSNQIKVVPSEPMQSDQNIFISQSNNTNTNNSIKIYKSSSHNVTIKPTTSSSTNNRPIIRLQPMPSSNQKKNSIIISKSESFIRSLGSSQNISVNSTSSQIIKTVSTSITTPVVYENQREIEVTELMELKSEIDYHPNGEVNQNCHVCGRIEPPGLSQISEAEELVVDWAHCDFCHKWVHLQPCCDSRCVQPDNRFKCIVCIKQQNDEELEKIMNTEISNEIGATMCIQEDETFYLLNESENPSIEDSVQLISTDNPQNSINTEIDSI
Sbjct:  153 FYAFLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNKPDHIWMTDEVSIACDNSNVPKILPITIQRPQSNTYWNPTAAVLGAGNAAGDKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFRPLIPQRPVILLYDGHLQFVTVRVLEKAKEDNVLLFPLPPHPPYNHCVESSCFAAYPKYFTKRIQKYHDDFKRNVNKTNVSRIICQAYEWALQPINLIQTFFKLGICPYNNLSNSLAPYMPNSSDDDPNDENMDSLDMTESEFMHNNSNNISMFSGRDPLSNMPLAHSPIIDRSYNPNDNFSIMQNNVSQSSFNQNDFFAPHSLNTSGMYPSLGNIKVLDNMASKAMNQMHTQRAEYNHSKVRASLPVNSICENSQPKILSIKNSNASKNSIVLRTTQSQSTPLCKVSPNSSFPVYSIGTSNQIKVVPSEPMQSDQNIFISQSNNTNTNNSIKIYKSSSHNVTIKPTTSSSTNNRPIIRLQPMPSSNQKKNSIIISKSESFIRSLGSSQNISVNSTSSQIIKTVSTSITTPVVYENQREIEVTELMELKSEIDYHPNGEVNQNCHVCGRIEPPGLSQISEAEELVVDWAHCDFCHKWVHLQPCCDSRCVQPDNRFKCIVCIKQQNDEELEKIMNTEISNEIGATMCIQEDETFYLLNESENPSIEDSVQLISTDNPQNSINTEIDSI 869

HSP 2 Score: 340.887 bits (873), Expect = 1.326e-102
Identity = 156/157 (99.36%), Postives = 156/157 (99.36%), Query Frame = 3 
Query:   63 MRDNDEYWEGNDDDNDSKCFQQQVLFIHDPYVNQANKPKTRRRRWTQKDMTNAFNAVKCTGMSLRGAASHYNVPESTLRDRVHGRVSLDCSRPGPPTFFTFEEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVDRIAPFKFLNPSQAWFYAFF 533
            MRDNDEYWEGNDDDNDSKCFQQQVLFIHDPYVNQANKPKTRRRRWTQKDMTNAFNAVKCTGMSLRGAASHYNVPESTLRDRVHGRVSLDCSRPGPPTFFTFEEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVDRIAPFKFLNPSQAWFYAF 
Sbjct:    1 MRDNDEYWEGNDDDNDSKCFQQQVLFIHDPYVNQANKPKTRRRRWTQKDMTNAFNAVKCTGMSLRGAASHYNVPESTLRDRVHGRVSLDCSRPGPPTFFTFEEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVDRIAPFKFLNPSQAWFYAFL 157
The following BLAST results are available for this feature:
BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
si:rp71-1d10.81.270e-624.05si:rp71-1d10.8 [Source:ZFIN;Acc:ZDB-GENE-141216-27... [more]
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BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DDE superfamily endonuclease CENP B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DDE superfamily endonuclease CENP B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3TSG71.590e-16660.89Uncharacterized protein OS=Rodentolepis nana OX=10... [more]
A0A0R3SRV61.492e-16560.15Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A564YDK91.556e-16560.15Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A4E0RTS93.707e-16460.89DDE superfamily endonuclease CENP B OS=Fasciola he... [more]
A0A5K4F1Q57.459e-16460.95Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
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BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DDE superfamily endonuclease CENP B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DDE superfamily endonuclease CENP B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000018934.11.326e-10299.72SMESG000018934.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30007093 ID=SMED30007093|Name=DDE superfamily endonuclease CENP B|organism=Schmidtea mediterranea sexual|type=transcript|length=2903bp
TGATTTGTAAAATTTGTATATCAATTTGAAATAATAATAATCCAATTGCT
ATATAGAAAATAATGAGAGATAATGATGAATACTGGGAAGGTAATGACGA
TGATAATGATAGTAAATGTTTCCAACAGCAAGTTCTATTTATTCATGATC
CTTATGTAAATCAAGCTAATAAACCTAAAACTAGGCGAAGAAGGTGGACT
CAAAAAGATATGACAAATGCATTTAATGCAGTTAAATGTACTGGTATGTC
TCTTAGAGGTGCTGCTAGTCATTATAATGTCCCCGAGTCTACCTTACGGG
ATAGAGTTCATGGACGAGTGAGTCTAGATTGTTCTAGACCTGGCCCTCCT
ACTTTTTTCACATTTGAAGAAGAGAAAAAAATGGTTGATCATATATTATT
CATGAGTAAAATTGGATATCCGTATACAAGAAATCAAGTTGTAGAACTTG
CTGGTGATATGACAAAAGCAGTTGATAGAATCGCACCATTTAAATTTTTA
AACCCTAGTCAAGCATGGTTTTATGCTTTTTTTAAATCGTTGGCCAGACC
TCAAAAATTATCTATATGGGCCAAGAAGTAACAGAAAAAGCAAAGGTGTG
TCAGCTGAATCTATTCAAGCATATTATGAAAACCTGGATAAAGTTCTTAT
TAAATATGATATAAAAAATAAGCCGGATCACATATGGATGACAGATGAAG
TTAGTATTGCTTGTGACAATTCAAACGTTCCAAAGATTTTACCAATTACT
ATACAAAGACCACAATCAAATACTTATTGGAATCCAACGGCGGCAGTTTT
AGGGGCAGGAAATGCTGCTGGTGATAAAATTCCTGCATTCCTTATGTTTA
AAGCTAGTGAAATTAGTGAAGAAATGATGGAAGGGTCCGTGAAAGGATCG
AAGTTTGCTACATCAAGTAATGGCTGGGTGAATGCTGACGCCTTTATACA
GTGGTACGAACGCCATTTTCGTCCACTTATTCCTCAAAGACCCGTTATCC
TTCTTTATGATGGACATTTACAATTTGTCACAGTGAGAGTTCTTGAAAAG
GCTAAAGAAGACAATGTTCTGTTATTTCCTTTACCTCCTCATCCTCCTTA
TAATCATTGTGTCGAAAGTTCGTGTTTTGCTGCATATCCAAAATATTTTA
CAAAACGAATTCAAAAATATCACGATGATTTCAAGCGCAATGTTAATAAA
ACTAATGTTAGTCGAATTATTTGCCAGGCTTATGAATGGGCTCTTCAACC
CATCAATCTTATTCAAACCTTTTTCAAACTCGGAATATGCCCATATAACA
ATCTATCCAATAGTCTGGCACCATACATGCCTAATAGCAGTGACGATGAT
CCAAACGATGAAAATATGGATAGTTTAGACATGACGGAATCTGAATTTAT
GCACAACAATTCTAATAATATATCCATGTTTTCTGGCCGCGATCCTCTCT
CAAATATGCCTCTTGCTCACTCACCTATCATCGATAGATCTTATAATCCT
AATGACAATTTTTCGATTATGCAGAACAATGTGTCCCAATCAAGCTTTAA
CCAAAATGATTTCTTTGCTCCCCATTCACTCAATACATCTGGCATGTATC
CTAGCCTTGGCAACATAAAGGTCCTAGATAATATGGCATCGAAGGCAATG
AATCAAATGCATACGCAAAGAGCGGAATACAACCATTCAAAAGTTCGTGC
TTCCCTTCCTGTAAACTCCATTTGTGAAAATAGCCAACCAAAAATATTAT
CCATTAAAAATTCTAATGCATCAAAAAATTCAATTGTTTTACGAACAACC
CAGTCTCAATCTACTCCACTTTGTAAAGTTTCTCCCAATAGCTCATTTCC
GGTCTATTCAATAGGTACGTCGAATCAAATCAAAGTAGTTCCTTCTGAGC
CGATGCAGTCCGATCAAAATATTTTCATTTCTCAATCAAATAACACAAAT
ACTAATAATTCAATAAAAATTTATAAGTCATCATCACACAATGTTACAAT
CAAACCTACAACTTCCAGCTCGACTAACAACCGGCCAATTATAAGACTGC
AACCAATGCCTTCTTCCAATCAGAAGAAAAATTCAATTATCATATCAAAA
TCCGAATCATTTATCCGAAGCCTTGGTTCATCGCAAAATATTTCGGTGAA
TTCTACCAGTAGCCAAATTATCAAAACTGTTAGCACTTCGATTACAACTC
CAGTTGTTTATGAAAATCAACGTGAAATAGAAGTCACAGAGTTGATGGAG
TTAAAATCAGAAATCGATTACCATCCAAATGGCGAAGTCAACCAAAATTG
CCATGTGTGTGGTAGAATCGAGCCACCGGGTTTGTCACAGATATCTGAAG
CCGAGGAACTGGTGGTCGATTGGGCACATTGTGATTTTTGTCACAAGTGG
GTCCATTTACAGCCCTGTTGTGACAGCAGATGCGTTCAGCCGGACAACAG
GTTCAAATGTATTGTGTGCATTAAACAACAAAATGATGAAGAGCTCGAGA
AAATCATGAACACGGAAATTAGCAATGAAATCGGAGCTACCATGTGTATT
CAGGAAGATGAAACGTTTTATTTATTGAATGAATCAGAAAATCCGAGTAT
AGAAGATTCGGTTCAGTTAATTTCTACTGACAATCCTCAAAACTCCATAA
ATACCGAAATCGATAGCATTTTATGAAATTAATTATATTTCAATAATTTG
ATTTGTGTTAATAATTCGTTGATTTCTATTTGCTTGTTCTCAATTCATTT
TAAAATCGACAATTATTTCCTTGTCTATATTTCGATTTTATTTTTCGAGT
GATTTACCAATGTTTGTTTGTAAATATTTGTTATCTTATGTTTACCATGT
TTATATTAAAAATAATTATCGATACTTAATAAAATGCATTAATTGAAAAA
AAA
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protein sequence of SMED30007093-orf-1

>SMED30007093-orf-1 ID=SMED30007093-orf-1|Name=SMED30007093-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=173bp
MRDNDEYWEGNDDDNDSKCFQQQVLFIHDPYVNQANKPKTRRRRWTQKDM
TNAFNAVKCTGMSLRGAASHYNVPESTLRDRVHGRVSLDCSRPGPPTFFT
FEEEKKMVDHILFMSKIGYPYTRNQVVELAGDMTKAVDRIAPFKFLNPSQ
AWFYAFFKSLARPQKLSIWAKK*
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protein sequence of SMED30007093-orf-2

>SMED30007093-orf-2 ID=SMED30007093-orf-2|Name=SMED30007093-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=718bp
MLFLNRWPDLKNYLYGPRSNRKSKGVSAESIQAYYENLDKVLIKYDIKNK
PDHIWMTDEVSIACDNSNVPKILPITIQRPQSNTYWNPTAAVLGAGNAAG
DKIPAFLMFKASEISEEMMEGSVKGSKFATSSNGWVNADAFIQWYERHFR
PLIPQRPVILLYDGHLQFVTVRVLEKAKEDNVLLFPLPPHPPYNHCVESS
CFAAYPKYFTKRIQKYHDDFKRNVNKTNVSRIICQAYEWALQPINLIQTF
FKLGICPYNNLSNSLAPYMPNSSDDDPNDENMDSLDMTESEFMHNNSNNI
SMFSGRDPLSNMPLAHSPIIDRSYNPNDNFSIMQNNVSQSSFNQNDFFAP
HSLNTSGMYPSLGNIKVLDNMASKAMNQMHTQRAEYNHSKVRASLPVNSI
CENSQPKILSIKNSNASKNSIVLRTTQSQSTPLCKVSPNSSFPVYSIGTS
NQIKVVPSEPMQSDQNIFISQSNNTNTNNSIKIYKSSSHNVTIKPTTSSS
TNNRPIIRLQPMPSSNQKKNSIIISKSESFIRSLGSSQNISVNSTSSQII
KTVSTSITTPVVYENQREIEVTELMELKSEIDYHPNGEVNQNCHVCGRIE
PPGLSQISEAEELVVDWAHCDFCHKWVHLQPCCDSRCVQPDNRFKCIVCI
KQQNDEELEKIMNTEISNEIGATMCIQEDETFYLLNESENPSIEDSVQLI
STDNPQNSINTEIDSIL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR021483DUF3136
IPR007889HTH_Psq
IPR009057Homeobox-like_sf
IPR013083Znf_RING/FYVE/PHD
IPR004875DDE_SF_endonuclease_dom
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0003676nucleic acid binding
GO:0004519endonuclease activity
Vocabulary: biological process
TermDefinition
GO:0090305nucleic acid phosphodiester bond hydrolysis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.10.10.60coord: 45..87
e-value: 5.1E-8
score: 34.3
IPR007889DNA binding HTH domain, Psq-typePFAMPF05225HTH_psqcoord: 49..88
e-value: 2.1E-7
score: 30.6
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 41..89