Protein kinase domain-containing protein

Overview


Name	Protein kinase domain-containing protein
Smed ID	SMED30007007
Length (bp)	1679

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein kinase domain-containing protein (SMED30007007) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein kinase domain-containing protein (SMED30007007) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein kinase domain-containing protein (SMED30007007) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein kinase domain-containing protein (SMED30007007) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30007007

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30007007	h1SMcG0010616	Contig2909	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30007007	h1SMcG0012943	Contig2909	GPL15192	PMID:23079596 Forsthoefel et al., 2012
Smed sexual biotype	SMED30007007	h1SMcG0012943	Contig22846	newmark_ests	PMID:29674431 Fincher et al., 2018
gut	SMED30007007	h1SMcG0012943	dd_Smed_v4_4373_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30007007	h1SMcG0012943	dd_Smed_v4_4373_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: TESK2 (testis associated actin remodelling kinase 2 [Source:HGNC Symbol;Acc:HGNC:11732])

HSP 1 Score: 189.889 bits (481), Expect = 1.578e-52
Identity = 102/278 (36.69%), Postives = 166/278 (59.71%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVR--ADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKIN 1117
            IGSGFF++V+ V H      MA K+   + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++     L W+ RV +A DIA GL YLH + + HRDL+++N L+ + ++          Y AV+ADFGL   + DV   +++++ VG+PF+ APE L++E PY+  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QL  +CC +    RP+     + +   EI   L    +E  +K+ 
Sbjct:   64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNL-HLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDEN---------GYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDE-PYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRPSFVEIGKTL--EEILSRLQEEEQERDRKLQ 328

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BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: TESK1 (testis associated actin remodelling kinase 1 [Source:HGNC Symbol;Acc:HGNC:11731])

HSP 1 Score: 182.185 bits (461), Expect = 2.041e-49
Identity = 100/296 (33.78%), Postives = 164/296 (55.41%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNM----KDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLD---YKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHSYNVNNQFRGA 1159
            IG+GFF++VY V H      M  K+ K   +    ++E++L+  L H NIL+F G C++ G    LTE+++ G + +L+    P L W  R+H+A DIA+GL YLH + V HRDL+++N L+ +             + AV+ DFGL   +    +  R + ++ VG+P++ APE L+ E  YD  +DVF+FG++LCELI  +  DP+++PRT  +GLD   ++ L +  DCP     LA+ CC +     P+ ++ + +I ++  +I       EP        ++N  +  RG 
Sbjct:   63 IGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEP-LSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCLVRRED---------RGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGEL-YDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTL-VGDDCPLPFLLLAIHCCNLE----PSTRAPFTEITQHLEWI--LEQLPEPAPLTRTALTHNQGSVARGG 340

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Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNM----KDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLD---YKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHSYNVNNQFRGA 1159
            IG+GFF++VY V H      M  K+ K   +    ++E++L+  L H NIL+F G C++ G    LTE+++ G + +L+    P L W  R+H+A DIA+GL YLH + V HRDL+++N L+ +             + AV+ DFGL   +    +  R + ++ VG+P++ APE L+ E  YD  +DVF+FG++LCELI  +  DP+++PRT  +GLD   ++ L +  DCP     LA+ CC +     P+ ++ + +I ++  +I       EP        ++N  +  RG 
Sbjct:   63 IGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEP-LSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCLVRRED---------RGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGEL-YDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTL-VGDDCPLPFLLLAIHCCNLE----PSTRAPFTEITQHLEWI--LEQLPEPAPLTRTALTHNQGSVARGG 340

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BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: TESK2 (testis associated actin remodelling kinase 2 [Source:HGNC Symbol;Acc:HGNC:11732])

HSP 1 Score: 168.703 bits (426), Expect = 4.909e-45
Identity = 84/212 (39.62%), Postives = 138/212 (65.09%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVR--ADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTN 922
            IGSGFF++V+ V H      MA K+   + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++     L W+ RV +A DIA GL YLH + + HRDL+++N L+ + ++          Y AV+ADFGL   + DV   +++++ VG+PF+ APE L++E PY+  +DVFS+G++LCE+I  ++ DP+++PRT 
Sbjct:   64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNL-HLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDEN---------GYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDE-PYNEKADVFSYGIILCEIIARIQADPDYLPRTE 264

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BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: LIMK1 (LIM domain kinase 1 [Source:HGNC Symbol;Acc:HGNC:6613])

HSP 1 Score: 147.517 bits (371), Expect = 3.062e-37
Identity = 87/270 (32.22%), Postives = 140/270 (51.85%), Query Frame = 2

Query:  287 DIIGSGFFAKVYIVYH----VVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDV--------------RADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKR----DCPKWIHQLALDCCVISISRRPT 1030
            +++G G F +   V H     V+ +K   +  + TQ    F+KE+K+++ L H N+LKF G    +    ++TE++  G +  +I+       WS RV  A+DIA G+ YLH   +IHRDL++ N L+ + ++             V+ADFGL   M D               R  R + VGNP++ APE +   S YD   DVFSFG++LCE+I  +  DP+++PRT  +GL+ +   + R    +CP     + + CC +   +RP+
Sbjct:  309 EVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQ--RTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKN------------VVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRS-YDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGF-LDRYCPPNCPPSFFPITVRCCDLDPEKRPS 562

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BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: C24A1.3 (pep chromosome:WBcel235:III:692547:696456:-1 gene:WBGene00016030.1 transcript:C24A1.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C24A1.3)

HSP 1 Score: 104.375 bits (259), Expect = 3.619e-23
Identity = 74/247 (29.96%), Postives = 125/247 (50.61%), Query Frame = 2

Query:  248 NLCYSDKDFKSNLDIIGSGFFAKVYI------VYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYN-GVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQF---VIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTV-GNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPI 955
            +LC ++ +F+ +   IGSG F KVY       +  V     MAF     T   +   +E+ +L  L H N++ F G  L +   F  +TEF++ G++ RL+ +E  ++D + R+ I+ D+A+G+ YLH+     VIHRDL++ NIL+H               R+V+ADFG    +     + ++   GN  + APE       YD   DVFSF +++ E+ T        +P +++Y   +  +P+
Sbjct:  510 HLCLAEIEFQES---IGSGSFGKVYKGTYRGKLVAVKRYRAMAFGCKSET---DMLCREVSILSRLAHPNVVAFVGTSLDDPSQFAIITEFVENGSLFRLLHEEKRVMDPAFRLRISLDVARGMRYLHESAAKPVIHRDLNSHNILIHADG------------RSVVADFGESRFVCQREDENLTKQPGNLRWMAPEVFSQSGKYDRKVDVFSFALVIWEIHTA------ELPFSHRYKCSFYSIPV 732

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BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56])

HSP 1 Score: 102.064 bits (253), Expect = 1.208e-22
Identity = 76/258 (29.46%), Postives = 132/258 (51.16%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKP-TQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC--LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELIT-GLKNDPNFIPR--TNKYGLDYKKLPIKRDCPKWIH-QLALDCCVISISRRPTMKSAY 1045
            +G G F +V+      + +++A K  KP T S   F++E +++K  +H N++K Y  C     F  +TE++  G++ + +  +G  L     V +A  IA G++YL ++ ++HRDL+A N+L+         + +       +ADFGL   L  +D+   R        +TAPE     + +   SDV+S+G+LL E++T G    P    R    +  L Y ++P+ R CP+ I+ ++ L C   +  RRPT  + Y
Sbjct:  268 LGDGNFGEVWYGKWRGI-VEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLV--------GDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGN-FTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGY-RMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLY 514

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Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKP-TQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC--LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELIT-GLKNDPNFIPR--TNKYGLDYKKLPIKRDCPKWIH-QLALDCCVISISRRPTMKSAY 1045
            +G G F +V+      + +++A K  KP T S   F++E +++K  +H N++K Y  C     F  +TE++  G++ + +  +G  L     V +A  IA G++YL ++ ++HRDL+A N+L+         + +       +ADFGL   L  +D+   R        +TAPE     + +   SDV+S+G+LL E++T G    P    R    +  L Y ++P+ R CP+ I+ ++ L C   +  RRPT  + Y
Sbjct:  268 LGDGNFGEVWYGKWRGI-VEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLV--------GDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGN-FTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGY-RMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLY 514

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BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56])

HSP 1 Score: 101.679 bits (252), Expect = 1.514e-22
Identity = 76/258 (29.46%), Postives = 132/258 (51.16%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKP-TQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC--LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELIT-GLKNDPNFIPR--TNKYGLDYKKLPIKRDCPKWIH-QLALDCCVISISRRPTMKSAY 1045
            +G G F +V+      + +++A K  KP T S   F++E +++K  +H N++K Y  C     F  +TE++  G++ + +  +G  L     V +A  IA G++YL ++ ++HRDL+A N+L+         + +       +ADFGL   L  +D+   R        +TAPE     + +   SDV+S+G+LL E++T G    P    R    +  L Y ++P+ R CP+ I+ ++ L C   +  RRPT  + Y
Sbjct:  272 LGDGNFGEVWYGKWRGI-VEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLV--------GDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGN-FTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGY-RMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLY 518

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56])

HSP 1 Score: 101.679 bits (252), Expect = 1.514e-22
Identity = 76/258 (29.46%), Postives = 132/258 (51.16%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKP-TQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC--LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELIT-GLKNDPNFIPR--TNKYGLDYKKLPIKRDCPKWIH-QLALDCCVISISRRPTMKSAY 1045
            +G G F +V+      + +++A K  KP T S   F++E +++K  +H N++K Y  C     F  +TE++  G++ + +  +G  L     V +A  IA G++YL ++ ++HRDL+A N+L+         + +       +ADFGL   L  +D+   R        +TAPE     + +   SDV+S+G+LL E++T G    P    R    +  L Y ++P+ R CP+ I+ ++ L C   +  RRPT  + Y
Sbjct:  272 LGDGNFGEVWYGKWRGI-VEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLV--------GDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGN-FTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGY-RMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLY 518

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BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: cdi (gene:FBgn0004876 transcript:FBtr0305321)

HSP 1 Score: 183.341 bits (464), Expect = 4.499e-49
Identity = 96/275 (34.91%), Postives = 157/275 (57.09%), Query Frame = 2

Query:  245 INLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDY----KKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIV 1057
            ++  YS  DF    + IGSGFF++VY V H      M  K+ +   +    ++E++LL  L+H NIL F G C+  G    LTE+++ G++ +L+  +  +L  + ++ +A  IA+G+ Y+HD  + HRDL+++N+L+    ++         Y AV+ DFGL   +      R+ TVG+P++ +PE LK +  YD +SDVFSFG++ CE+I  ++ DP+ +PRT  +GLDY    +  P+  D P    +LA  CC+     RPT   A +K+ 
Sbjct:  102 VSALYSVDDFVK--EKIGSGFFSEVYKVTHRTTGQVMVLKMNQLRANRPNMLREVQLLNKLSHANILSFMGVCVQEGQLHALTEYINGGSLEQLLANKEVVLSATQKIRLALGIARGMSYVHDAGIFHRDLTSKNVLIRNLAND--------QYEAVVGDFGLAAKIPVKSKSRLETVGSPYWVSPECLKGQW-YDQTSDVFSFGIIQCEIIARIEADPDMMPRTASFGLDYLAFVELCPM--DTPPVFLRLAFYCCLYDAKSRPTFHDATKKLT 363

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: cdi (gene:FBgn0004876 transcript:FBtr0083716)

HSP 1 Score: 182.57 bits (462), Expect = 1.297e-48
Identity = 97/276 (35.14%), Postives = 158/276 (57.25%), Query Frame = 2

Query:  245 INLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMK-DVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDY----KKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIV 1057
            ++  YS  DF    + IGSGFF++VY V H      M  K+ +   +    ++E++LL  L+H NIL F G C+  G    LTE+++ G++ +L+  +  +L  + ++ +A  IA+G+ Y+HD  + HRDL+++N+L+    ++         Y AV+ DFGL   +    R  R+ TVG+P++ +PE LK +  YD +SDVFSFG++ CE+I  ++ DP+ +PRT  +GLDY    +  P+  D P    +LA  CC+     RPT   A +K+ 
Sbjct:  102 VSALYSVDDFVK--EKIGSGFFSEVYKVTHRTTGQVMVLKMNQLRANRPNMLREVQLLNKLSHANILSFMGVCVQEGQLHALTEYINGGSLEQLLANKEVVLSATQKIRLALGIARGMSYVHDAGIFHRDLTSKNVLIRNLAND--------QYEAVVGDFGLAAKIPVKSRKSRLETVGSPYWVSPECLKGQW-YDQTSDVFSFGIIQCEIIARIEADPDMMPRTASFGLDYLAFVELCPM--DTPPVFLRLAFYCCLYDAKSRPTFHDATKKLT 364

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: LIMK1 (gene:FBgn0283712 transcript:FBtr0301831)

HSP 1 Score: 140.584 bits (353), Expect = 9.425e-35
Identity = 89/295 (30.17%), Postives = 143/295 (48.47%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYH----VVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRM--------------------------------------STVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIK--RDCPKWIHQLALDCCVISISRRPTMKSAY 1045
            +G GFF KV+ V H     V+ LK   +  +  Q    F+KE+ +L+ L+H ++LKF G    +     +TE++  G +  LI     +L W  RV +A DIA G+ YLH   +IHRDL++ N L+ + +S             ++ADFGL    + V A R+                                      + VGNP++ APE +K    YD   DVFSFG++LCE+I  ++ DP+F+PR + + L+ ++   K    CP+   ++A  CC ++   RP  ++ +
Sbjct:  193 LGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQ--RNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVREDRS------------VIVADFGLA---RSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLK-YDEKVDVFSFGIMLCEIIGRVEADPDFMPRNSDFSLNQQEFREKFCAQCPEPFVKVAFVCCDLNPDMRPCFETLH 469

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BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: LIMK1 (gene:FBgn0283712 transcript:FBtr0073661)

HSP 1 Score: 140.584 bits (353), Expect = 1.039e-34
Identity = 89/295 (30.17%), Postives = 143/295 (48.47%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYH----VVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRM--------------------------------------STVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIK--RDCPKWIHQLALDCCVISISRRPTMKSAY 1045
            +G GFF KV+ V H     V+ LK   +  +  Q    F+KE+ +L+ L+H ++LKF G    +     +TE++  G +  LI     +L W  RV +A DIA G+ YLH   +IHRDL++ N L+ + +S             ++ADFGL    + V A R+                                      + VGNP++ APE +K    YD   DVFSFG++LCE+I  ++ DP+F+PR + + L+ ++   K    CP+   ++A  CC ++   RP  ++ +
Sbjct:  202 LGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQ--RNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVREDRS------------VIVADFGLA---RSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLK-YDEKVDVFSFGIMLCEIIGRVEADPDFMPRNSDFSLNQQEFREKFCAQCPEPFVKVAFVCCDLNPDMRPCFETLH 478

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BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: LIMK1 (gene:FBgn0283712 transcript:FBtr0073659)

HSP 1 Score: 140.198 bits (352), Expect = 1.714e-34
Identity = 89/295 (30.17%), Postives = 143/295 (48.47%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYH----VVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRM--------------------------------------STVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIK--RDCPKWIHQLALDCCVISISRRPTMKSAY 1045
            +G GFF KV+ V H     V+ LK   +  +  Q    F+KE+ +L+ L+H ++LKF G    +     +TE++  G +  LI     +L W  RV +A DIA G+ YLH   +IHRDL++ N L+ + +S             ++ADFGL    + V A R+                                      + VGNP++ APE +K    YD   DVFSFG++LCE+I  ++ DP+F+PR + + L+ ++   K    CP+   ++A  CC ++   RP  ++ +
Sbjct:  385 LGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQ--RNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVREDRS------------VIVADFGL---ARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLK-YDEKVDVFSFGIMLCEIIGRVEADPDFMPRNSDFSLNQQEFREKFCAQCPEPFVKVAFVCCDLNPDMRPCFETLH 661

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BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: tesk2 (testis associated actin remodelling kinase 2 [Source:ZFIN;Acc:ZDB-GENE-070209-68])

HSP 1 Score: 196.052 bits (497), Expect = 1.656e-54
Identity = 101/274 (36.86%), Postives = 166/274 (60.58%), Query Frame = 2

Query:  287 DIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC--LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTRE 1099
            + IGSGFF++VY V H   +  MA K+ K + +    ++E++L+  L+H NIL+F G C+  G    LTE+++ GN+ +L++     L W+ RV +A +IA GL YLH + + HRDL+++N L+   +S+ N       Y A++ DFGL   +   D   +++S VG+PF+ APE L++E PY+  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QLA +CC +    RP+     +++ E +  +    + RE
Sbjct:   62 EWIGSGFFSEVYKVRHRASDQVMALKMNKLSSNRANMLREVQLMNRLSHPNILRFMGVCVQEGQLHALTEYINGGNLEQLLDSNK-FLSWATRVKLALEIAMGLSYLHSKGIFHRDLTSKNCLI---KSDENG------YTAIVGDFGLAEKIPSHDYEGEKLSVVGSPFWMAPEVLRDE-PYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYHAFQHMVGDCPADFLQLAFNCCNMDPKLRPSFPDIVKRLEEIQKKLKAEESDRE 324

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Query:  287 DIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC--LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTRE 1099
            + IGSGFF++VY V H   +  MA K+ K + +    ++E++L+  L+H NIL+F G C+  G    LTE+++ GN+ +L++     L W+ RV +A +IA GL YLH + + HRDL+++N L+   +S+ N       Y A++ DFGL   +   D   +++S VG+PF+ APE L++E PY+  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QLA +CC +    RP+     +++ E +  +    + RE
Sbjct:   62 EWIGSGFFSEVYKVRHRASDQVMALKMNKLSSNRANMLREVQLMNRLSHPNILRFMGVCVQEGQLHALTEYINGGNLEQLLDSNK-FLSWATRVKLALEIAMGLSYLHSKGIFHRDLTSKNCLI---KSDENG------YTAIVGDFGLAEKIPSHDYEGEKLSVVGSPFWMAPEVLRDE-PYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYHAFQHMVGDCPADFLQLAFNCCNMDPKLRPSFPDIVKRLEEIQKKLKAEESDRE 324

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BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: si:dkeyp-75h12.2 (si:dkeyp-75h12.2 [Source:ZFIN;Acc:ZDB-GENE-030131-7512])

HSP 1 Score: 179.489 bits (454), Expect = 1.651e-48
Identity = 93/263 (35.36%), Postives = 149/263 (56.65%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKD----VRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIK-RDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENE 1066
            IGSGFF++V+ V H      MA K+     +    +KE++L+  L H NIL+F G C++ G    LTE+++ GN+ +L+  +  LL WS R++++ DIA+GL YLH + + HRDL+++N L+                 AV+ DFGL   + D         ++ VG+P++ APE L+ E  Y+   DVF++G++LCE+I  ++ DP+F+PRT  +GLD +   +   DCP     LA+ CC +S   RP       ++ + E
Sbjct:   54 IGSGFFSEVFKVQHRSTGQVMALKMNTMASNKANMLKEVQLMNRLRHPNILRFVGVCVHEGHLHALTEYINGGNLEQLLNSD-VLLSWSVRINLSLDIARGLQYLHSKGIFHRDLTSKNCLVRWENGHCT---------AVVGDFGLAEKIPDHSEEAEKQSLAVVGSPYWMAPEVLRGER-YNEKVDVFAYGIILCEIIGRIQADPDFLPRTEDFGLDVEAFRLMVEDCPAHFFNLAVVCCGMSPDSRPCFSEVVAELEKRE 305

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Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKD----VRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIK-RDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENE 1066
            IGSGFF++V+ V H      MA K+     +    +KE++L+  L H NIL+F G C++ G    LTE+++ GN+ +L+  +  LL WS R++++ DIA+GL YLH + + HRDL+++N L+                 AV+ DFGL   + D         ++ VG+P++ APE L+ E  Y+   DVF++G++LCE+I  ++ DP+F+PRT  +GLD +   +   DCP     LA+ CC +S   RP       ++ + E
Sbjct:   54 IGSGFFSEVFKVQHRSTGQVMALKMNTMASNKANMLKEVQLMNRLRHPNILRFVGVCVHEGHLHALTEYINGGNLEQLLNSD-VLLSWSVRINLSLDIARGLQYLHSKGIFHRDLTSKNCLVRWENGHCT---------AVVGDFGLAEKIPDHSEEAEKQSLAVVGSPYWMAPEVLRGER-YNEKVDVFAYGIILCEIIGRIQADPDFLPRTEDFGLDVEAFRLMVEDCPAHFFNLAVVCCGMSPDSRPCFSEVVAELEKRE 305

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BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: zgc:113162 (zgc:113162 [Source:ZFIN;Acc:ZDB-GENE-050522-530])

HSP 1 Score: 171.014 bits (432), Expect = 5.384e-48
Identity = 91/260 (35.00%), Postives = 146/260 (56.15%), Query Frame = 2

Query:  266 KDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRAD----RMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKL-PIKRDCPKWIHQLALDCCVISISRRPT 1030
            +DF + L  IG+GFF+KVY V H      M  K+ K     N  V+EI LL+ L+H NI+++ G C+       + E++  G +  L+ +    L W  ++ +  DI++G+ YLH + + HRDL+++N L+  +              AV+ DFGL   + D+ A+    ++S VG+ F+ APE L+ E PYD   DVFSFG++LCE++  +  DP  +PRT  YGLD +    + + CP+ + +L+  CC +   RRP+
Sbjct:   59 EDFSAEL--IGTGFFSKVYKVMHGTTKKVMVVKIYKNDVDQNSIVREISLLQKLSHPNIVRYLGICVKENKLYPILEYVSGGCLEELLARADVSLCWREKIELGCDISRGMAYLHYKNIYHRDLNSKNCLIRMSSR---------GREAVVTDFGLAREVGDLPANDPDRKLSLVGSAFWMAPEMLRGE-PYDRKVDVFSFGIMLCEILARIPADPEVLPRTKDYGLDVQAFRELVQGCPERVLELSASCCQMDAFRRPS 306

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BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: cnksr1 (connector enhancer of kinase suppressor of Ras 1 [Source:Xenbase;Acc:XB-GENE-493182])

HSP 1 Score: 194.512 bits (493), Expect = 2.669e-54
Identity = 98/249 (39.36%), Postives = 156/249 (62.65%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVR--ADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPT 1030
            IGSGFF++V+ V H   +  MA K+ K + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++    L  W+ RV +A DIA GL YLH + + HRDL+++N L+   +S          Y AV+ADFGL   + D    +++++ VG+P++ APE L++E PYD  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QL  +CC +    RP+
Sbjct:   60 IGSGFFSEVFKVRHRTSDQVMALKMNKLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNQHLT-WTVRVKLALDIALGLAYLHSKGIFHRDLTSKNCLIKSDES---------GYSAVVADFGLAEKIPDYSEGSEKLAVVGSPYWMAPEVLRDE-PYDEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDGFQHMVGDCPPDFLQLTFNCCNMDPKLRPS 297

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: cnksr1 (connector enhancer of kinase suppressor of Ras 1 [Source:Xenbase;Acc:XB-GENE-493182])

HSP 1 Score: 194.512 bits (493), Expect = 2.835e-54
Identity = 102/281 (36.30%), Postives = 170/281 (60.50%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVR--ADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNH 1126
            IGSGFF++V+ V H   +  MA K+ K + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++    L  W+ RV +A DIA GL YLH + + HRDL+++N L+   +S          Y AV+ADFGL   + D    +++++ VG+P++ APE L++E PYD  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QL  +CC +    RP+     +++   E  ++  RN    +++ +L+ 
Sbjct:   60 IGSGFFSEVFKVRHRTSDQVMALKMNKLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNQHLT-WTVRVKLALDIALGLAYLHSKGIFHRDLTSKNCLIKSDES---------GYSAVVADFGLAEKIPDYSEGSEKLAVVGSPYWMAPEVLRDE-PYDEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDGFQHMVGDCPPDFLQLTFNCCNMDPKLRPSFIDIAKQL---ENILNRLRNEEAERERKDLSE 326

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: cnksr1 (connector enhancer of kinase suppressor of Ras 1 [Source:Xenbase;Acc:XB-GENE-493182])

HSP 1 Score: 196.052 bits (497), Expect = 3.254e-54
Identity = 102/281 (36.30%), Postives = 170/281 (60.50%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVR--ADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNH 1126
            IGSGFF++V+ V H   +  MA K+ K + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++    L  W+ RV +A DIA GL YLH + + HRDL+++N L+   +S          Y AV+ADFGL   + D    +++++ VG+P++ APE L++E PYD  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QL  +CC +    RP+     +++   E  ++  RN    +++ +L+ 
Sbjct:   60 IGSGFFSEVFKVRHRTSDQVMALKMNKLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNQHLT-WTVRVKLALDIALGLAYLHSKGIFHRDLTSKNCLIKSDES---------GYSAVVADFGLAEKIPDYSEGSEKLAVVGSPYWMAPEVLRDE-PYDEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDGFQHMVGDCPPDFLQLTFNCCNMDPKLRPSFIDIAKQL---ENILNRLRNEEAERERKDLSE 326

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: cnksr1 (connector enhancer of kinase suppressor of Ras 1 [Source:Xenbase;Acc:XB-GENE-493182])

HSP 1 Score: 196.052 bits (497), Expect = 3.698e-54
Identity = 102/281 (36.30%), Postives = 170/281 (60.50%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVR--ADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNH 1126
            IGSGFF++V+ V H   +  MA K+ K + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++    L  W+ RV +A DIA GL YLH + + HRDL+++N L+   +S          Y AV+ADFGL   + D    +++++ VG+P++ APE L++E PYD  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QL  +CC +    RP+     +++   E  ++  RN    +++ +L+ 
Sbjct:   60 IGSGFFSEVFKVRHRTSDQVMALKMNKLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNQHLT-WTVRVKLALDIALGLAYLHSKGIFHRDLTSKNCLIKSDES---------GYSAVVADFGLAEKIPDYSEGSEKLAVVGSPYWMAPEVLRDE-PYDEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDGFQHMVGDCPPDFLQLTFNCCNMDPKLRPSFIDIAKQL---ENILNRLRNEEAERERKDLSE 326

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: cnksr1 (connector enhancer of kinase suppressor of Ras 1 [Source:Xenbase;Acc:XB-GENE-493182])

HSP 1 Score: 194.897 bits (494), Expect = 4.461e-54
Identity = 97/244 (39.75%), Postives = 154/244 (63.11%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVR--ADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISI 1015
            IGSGFF++V+ V H   +  MA K+ K + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++    L  W+ RV +A DIA GL YLH + + HRDL+++N L+   +S          Y AV+ADFGL   + D    +++++ VG+P++ APE L++E PYD  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QL  +CC + I
Sbjct:   60 IGSGFFSEVFKVRHRTSDQVMALKMNKLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNQHLT-WTVRVKLALDIALGLAYLHSKGIFHRDLTSKNCLIKSDES---------GYSAVVADFGLAEKIPDYSEGSEKLAVVGSPYWMAPEVLRDE-PYDEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDGFQHMVGDCPPDFLQLTFNCCNVGI 292

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Tesk2 (testis-specific kinase 2 [Source:MGI Symbol;Acc:MGI:2385204])

HSP 1 Score: 192.2 bits (487), Expect = 1.521e-53
Identity = 104/286 (36.36%), Postives = 170/286 (59.44%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKD--VRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRP-------TMKSAYQKIVENEIYID--LWRNTREPKKKI 1114
            IGSGFF++V+ V H      MA K+   + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++ +   L W+ RV +A DIA GL YLH + + HRDL+++N L+ + ++          Y AV+ADFGL   + D  +  ++++ VG+PF+ APE L++E PY+  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QL  +CC +    RP       T+K    ++ E E+  D  L    + P +K+
Sbjct:   64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSDL-YLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDEN---------GYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLRDE-PYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVGDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSRLPEEELERDRKLQPTAKGPLEKV 338

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Tesk1 (testis specific protein kinase 1 [Source:MGI Symbol;Acc:MGI:1201675])

HSP 1 Score: 182.57 bits (462), Expect = 9.347e-50
Identity = 103/299 (34.45%), Postives = 166/299 (55.52%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNM----KDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLD---YKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHS---YNVNNQFRGA 1159
            IG+GFF++VY V H      M  K+ K   + +  ++E++L+  L H NIL+F G C++ G    LTE+++ G + +L+    P L W  R+H+A DIA+GL YLH + V HRDL+++N L+ +             + AV+ DFGL   +    +  R + ++ VG+P++ APE L+ E  YD  +DVF+FG++LCELI  +  DP+++PRT  +GLD   ++ L +  DCP     LA+ CC    S  P+ ++ + +I ++   I   +    P  K  L  +   YN  +  RG 
Sbjct:   58 IGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEP-LSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRRED---------RGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPYWMAPEVLRGEL-YDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTL-VGNDCPLPFLLLAIHCC----SMEPSTRAPFTEITQHLEQILEQQPEATPLAKPPLTKAPLTYNQGSVPRGG 340

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Tesk2 (testis-specific kinase 2 [Source:MGI Symbol;Acc:MGI:2385204])

HSP 1 Score: 168.318 bits (425), Expect = 3.971e-45
Identity = 92/260 (35.38%), Postives = 156/260 (60.00%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKD--VRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKRDCPKWIHQLALDCCVISISR----RPTMKSAYQKI 1054
            IGSGFF++V+ V H      MA K+   + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++ +   L W+ RV +A DIA GL YLH + + HRDL+++N L+ + ++          Y AV+ADFGL   + D  +  ++++ VG+PF+ APE L++E PY+  +DVFS+G++LCE+I  ++ DP+++PRT    +D K  P   +  K + ++        + R    +PT K   +K+
Sbjct:   64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSDL-YLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDEN---------GYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLRDE-PYNEKADVFSYGIILCEIIARIQADPDYLPRTE---MDPKLRPSFEEIGKTLKEIMSRLPEEELERDRKLQPTAKGPLEKV 309

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BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Limk1 (LIM-domain containing, protein kinase [Source:MGI Symbol;Acc:MGI:104572])

HSP 1 Score: 147.517 bits (371), Expect = 2.458e-37
Identity = 87/270 (32.22%), Postives = 140/270 (51.85%), Query Frame = 2

Query:  287 DIIGSGFFAKVYIVYH----VVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDV--------------RADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKR----DCPKWIHQLALDCCVISISRRPT 1030
            +++G G F +   V H     V+ +K   +  + TQ    F+KE+K+++ L H N+LKF G    +    ++TE++  G +  +I+       WS RV  A+DIA G+ YLH   +IHRDL++ N L+ + ++             V+ADFGL   M D               R  R + VGNP++ APE +   S YD   DVFSFG++LCE+I  +  DP+++PRT  +GL+ +   + R    +CP     + + CC +   +RP+
Sbjct:  335 EVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQ--RTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRN------------VVVADFGLARLMIDEKNQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMINGRS-YDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGF-LDRYCPPNCPPSFFPITVRCCDLDPEKRPS 588

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Limk1 (LIM-domain containing, protein kinase [Source:MGI Symbol;Acc:MGI:104572])

HSP 1 Score: 147.132 bits (370), Expect = 3.778e-37
Identity = 87/270 (32.22%), Postives = 140/270 (51.85%), Query Frame = 2

Query:  287 DIIGSGFFAKVYIVYH----VVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDV--------------RADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKR----DCPKWIHQLALDCCVISISRRPT 1030
            +++G G F +   V H     V+ +K   +  + TQ    F+KE+K+++ L H N+LKF G    +    ++TE++  G +  +I+       WS RV  A+DIA G+ YLH   +IHRDL++ N L+ + ++             V+ADFGL   M D               R  R + VGNP++ APE +   S YD   DVFSFG++LCE+I  +  DP+++PRT  +GL+ +   + R    +CP     + + CC +   +RP+
Sbjct:  343 EVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQ--RTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRN------------VVVADFGLARLMIDEKNQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMINGRS-YDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGF-LDRYCPPNCPPSFFPITVRCCDLDPEKRPS 596

[Close]

BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8VCT9|TESK2_MOUSE (Dual specificity testis-specific protein kinase 2 OS=Mus musculus OX=10090 GN=Tesk2 PE=1 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 1.064e-52
Identity = 104/286 (36.36%), Postives = 170/286 (59.44%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKD--VRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRP-------TMKSAYQKIVENEIYID--LWRNTREPKKKI 1114
            IGSGFF++V+ V H      MA K+   + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++ +   L W+ RV +A DIA GL YLH + + HRDL+++N L+ + ++          Y AV+ADFGL   + D  +  ++++ VG+PF+ APE L++E PY+  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QL  +CC +    RP       T+K    ++ E E+  D  L    + P +K+
Sbjct:   64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSDL-YLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDEN---------GYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLRDE-PYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVGDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSRLPEEELERDRKLQPTAKGPLEKV 338

[Close]

BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q924U5|TESK2_RAT (Dual specificity testis-specific protein kinase 2 OS=Rattus norvegicus OX=10116 GN=Tesk2 PE=2 SV=1)

HSP 1 Score: 190.66 bits (483), Expect = 3.556e-52
Identity = 97/259 (37.45%), Postives = 160/259 (61.78%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKD--VRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVE 1060
            IGSGFF++V+ V H      MA K+   + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++     L W+ RV +A DIA GL YLH + + HRDL+++N L+ + ++          Y AV+ADFGL   + D  + +++++ VG+PF+ APE L++E PY+  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QL  +CC +    RP+ +   + + E
Sbjct:   64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNL-YLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDEN---------GYSAVVADFGLAEKIPDASIGSEKLAVVGSPFWMAPEVLRDE-PYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLEE 311

[Close]

BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q96S53|TESK2_HUMAN (Dual specificity testis-specific protein kinase 2 OS=Homo sapiens OX=9606 GN=TESK2 PE=1 SV=1)

HSP 1 Score: 189.889 bits (481), Expect = 7.577e-52
Identity = 102/278 (36.69%), Postives = 166/278 (59.71%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVR--ADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKIN 1117
            IGSGFF++V+ V H      MA K+   + +    +KE++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++     L W+ RV +A DIA GL YLH + + HRDL+++N L+ + ++          Y AV+ADFGL   + DV   +++++ VG+PF+ APE L++E PY+  +DVFS+G++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QL  +CC +    RP+     + +   EI   L    +E  +K+ 
Sbjct:   64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNL-HLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDEN---------GYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDE-PYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRPSFVEIGKTL--EEILSRLQEEEQERDRKLQ 328

[Close]

BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|O70146|TESK1_MOUSE (Dual specificity testis-specific protein kinase 1 OS=Mus musculus OX=10090 GN=Tesk1 PE=1 SV=3)

HSP 1 Score: 182.57 bits (462), Expect = 6.538e-49
Identity = 103/299 (34.45%), Postives = 166/299 (55.52%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNM----KDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLD---YKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHS---YNVNNQFRGA 1159
            IG+GFF++VY V H      M  K+ K   + +  ++E++L+  L H NIL+F G C++ G    LTE+++ G + +L+    P L W  R+H+A DIA+GL YLH + V HRDL+++N L+ +             + AV+ DFGL   +    +  R + ++ VG+P++ APE L+ E  YD  +DVF+FG++LCELI  +  DP+++PRT  +GLD   ++ L +  DCP     LA+ CC    S  P+ ++ + +I ++   I   +    P  K  L  +   YN  +  RG 
Sbjct:   58 IGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEP-LSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRRED---------RGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPYWMAPEVLRGEL-YDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTL-VGNDCPLPFLLLAIHCC----SMEPSTRAPFTEITQHLEQILEQQPEATPLAKPPLTKAPLTYNQGSVPRGG 340

[Close]

BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q15569|TESK1_HUMAN (Dual specificity testis-specific protein kinase 1 OS=Homo sapiens OX=9606 GN=TESK1 PE=1 SV=2)

HSP 1 Score: 182.185 bits (461), Expect = 9.800e-49
Identity = 100/296 (33.78%), Postives = 164/296 (55.41%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNM----KDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLD---YKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHSYNVNNQFRGA 1159
            IG+GFF++VY V H      M  K+ K   +    ++E++L+  L H NIL+F G C++ G    LTE+++ G + +L+    P L W  R+H+A DIA+GL YLH + V HRDL+++N L+ +             + AV+ DFGL   +    +  R + ++ VG+P++ APE L+ E  YD  +DVF+FG++LCELI  +  DP+++PRT  +GLD   ++ L +  DCP     LA+ CC +     P+ ++ + +I ++  +I       EP        ++N  +  RG 
Sbjct:   63 IGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEP-LSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCLVRRED---------RGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGEL-YDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTL-VGDDCPLPFLLLAIHCCNLE----PSTRAPFTEITQHLEWI--LEQLPEPAPLTRTALTHNQGSVARGG 340

[Close]

BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1E1XDE3 (Putative tyrosine kinase specific for activated gtp-bound (Fragment) OS=Amblyomma aureolatum OX=187763 PE=2 SV=1)

HSP 1 Score: 198.364 bits (503), Expect = 2.814e-54
Identity = 101/268 (37.69%), Postives = 164/268 (61.19%), Query Frame = 2

Query:  269 DFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC--LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKR----DCPKWIHQLALDCCVISISRRPTMKSAYQKI 1054
            DF S  + IGSGFF++VY V H         K+   + +    ++E++LL  L+H NIL+F G C++ G    LTE+++ G++ +LI++    L W+ R+ +A DIA+G+ YLH + V HRDL+++N+L+ + Q E      +    AV+ D GL   + + D R  R+  VG+P++ APE L   + YD  +DVFS+G++LCE+I  L+ DP+ +PRT  +G+D  +L ++R    DCP    +LAL CC++  S RPT +S  +++
Sbjct:   64 DFTS--EKIGSGFFSEVYKVTHRTTGQVCVLKMNTSSSNRPNMLREVQLLNRLSHRNILRFLGVCVHQGQLHALTEYINGGSLEQLIQRRSEPLPWALRLKLALDIARGMAYLHSRGVFHRDLTSKNVLIKRHQEEDGGAPTLT---AVVGDLGLAERIPVADCRDFRLPVVGSPYWMAPECLHG-AWYDQRADVFSYGIILCEMIVRLEADPDVLPRTADFGVD--RLALRRLCPDDCPPAFLRLALACCLVEPSTRPTFQSIVEQL 323

[Close]

BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A0P4W4F0 (Protein kinase domain-containing protein OS=Scylla olivacea OX=85551 PE=4 SV=1)

HSP 1 Score: 194.897 bits (494), Expect = 4.079e-53
Identity = 103/269 (38.29%), Postives = 162/269 (60.22%), Query Frame = 2

Query:  257 YSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYG---LDYKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKI 1054
            Y   DF  ++D IGSGFF++V+ V H V    M  K+ K   + +  ++E++L+  L+H NIL++YG C+  G    LTE+++ G++  LI      L W+ RV +A DIA G+ YLH Q V HRDL+++N+L+  TQ     E   +   AVIADFGL   +   +  R+  VG+P++ APE ++ +  YD+  DVFSFG+++CE+I   + DP+ +PRT+ +G   LD+ ++  ++DCP    QLA  CC I  + RP+ +    K+
Sbjct:   94 YRIDDF--HMDRIGSGFFSEVFKVRHRVTGDIMVLKMNKLMSNRHNMLREVELMNRLHHPNILRYYGVCVNEGQVHALTEYINGGSLDSLIGNRAVGLPWATRVSLALDIAHGMAYLHSQGVFHRDLTSKNVLIKHTQ-----EGGEHKLTAVIADFGLAAPIPHEKCMRLRQVGSPYWMAPEVIRGDW-YDHRVDVFSFGIIVCEMIARCEADPDILPRTHNFGVHYLDFYQM-CQQDCPALFLQLAFMCCQIDPASRPSFEELKAKL 353

[Close]

BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A224YTC1 (Center divider OS=Rhipicephalus zambeziensis OX=60191 PE=4 SV=1)

HSP 1 Score: 193.741 bits (491), Expect = 5.775e-53
Identity = 100/268 (37.31%), Postives = 162/268 (60.45%), Query Frame = 2

Query:  269 DFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC--LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKR----DCPKWIHQLALDCCVISISRRPTMKSAYQKI 1054
            DF S  + IGSGFF++VY V H         K+   + +    ++E++LL  L+H NIL+F G C++ G    LTE+++ G++ +LI++    L W  R+ +A DIA+G+ YLH + V HRDL+++N+L+ + Q E   +  + +  AV+ D GL   + +   R  R+  VG+P++ APE L   + YD  +DVFS+G++LCELI  L+ DP+ +PRT  +G+D  +L ++R    DCP    +LAL CC +  S RPT +   +++
Sbjct:   33 DFTS--EKIGSGFFSEVYKVTHRTTGQVCVLKMNTSSSNRPNMLREVQLLNRLSHRNILRFLGVCVHQGQLHALTEYINGGSLEQLIQRRSEPLSWELRMRLALDIARGMAYLHSRGVFHRDLTSKNVLIKRHQEE---DGALPTLTAVVGDLGLAERIPVSGCRDFRLPVVGSPYWMAPECLHG-AWYDQRADVFSYGIILCELIVRLEADPDVLPRTADFGVD--RLALRRLCPDDCPPAFLRLALACCQVEPSARPTFEGIVEQL 292

[Close]

BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A131YC96 (Center divider OS=Rhipicephalus appendiculatus OX=34631 PE=4 SV=1)

HSP 1 Score: 193.741 bits (491), Expect = 5.775e-53
Identity = 100/268 (37.31%), Postives = 162/268 (60.45%), Query Frame = 2

Query:  269 DFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC--LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKR----DCPKWIHQLALDCCVISISRRPTMKSAYQKI 1054
            DF S  + IGSGFF++VY V H         K+   + +    ++E++LL  L+H NIL+F G C++ G    LTE+++ G++ +LI++    L W  R+ +A DIA+G+ YLH + V HRDL+++N+L+ + Q E   +  + +  AV+ D GL   + +   R  R+  VG+P++ APE L   + YD  +DVFS+G++LCELI  L+ DP+ +PRT  +G+D  +L ++R    DCP    +LAL CC +  S RPT +   +++
Sbjct:   33 DFTS--EKIGSGFFSEVYKVTHRTTGQVCVLKMNTSSSNRPNMLREVQLLNRLSHRNILRFLGVCVHQGQLHALTEYINGGSLEQLIQRRSEPLSWELRMRLALDIARGMAYLHSRGVFHRDLTSKNVLIKRHQEE---DGALPTLTAVVGDLGLAERIPVSGCRDFRLPVVGSPYWMAPECLHG-AWYDQRADVFSYGIILCELIVRLEADPDVLPRTADFGVD--RLALRRLCPDDCPPAFLRLALACCQVEPSARPTFEGIVEQL 292

[Close]

BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A4W3I2H1 (Protein kinase domain-containing protein OS=Callorhinchus milii OX=7868 GN=tesk2 PE=4 SV=1)

HSP 1 Score: 197.593 bits (501), Expect = 4.722e-52
Identity = 100/249 (40.16%), Postives = 157/249 (63.05%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRAD--RMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPT 1030
            IG+GFF++VY V H + +  MA K+ K + +    ++E++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++     L W+ RV IA D+A GL YLH + V HRDL+++N L+ K ++          Y AV+ DFGL   + D+  D  ++S VG+PF+ APE L +E  Y+ ++DVFSFG++LCE+I  ++ DP+++PRT  +GLDY     +  DCP    QLA +CC +    RP+
Sbjct:   62 IGTGFFSEVYKVRHRISDQVMALKMNKMSSNRANMLREVQLMNRLSHPNILRFMGVCVHEGQLHALTEYINGGNLEQLLDSS-QHLPWTARVKIAHDLASGLSYLHLKGVFHRDLTSKNCLIKKEEN---------GYTAVVGDFGLAEKIPDLSVDIEKLSVVGSPFWMAPEMLHSEH-YNETADVFSFGIILCEIIARVQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLAFNCCNVDPKLRPS 299

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: tesk2 (testis associated actin remodelling kinase 2 [Source:NCBI gene;Acc:103031215])

HSP 1 Score: 197.978 bits (502), Expect = 4.835e-55
Identity = 101/272 (37.13%), Postives = 165/272 (60.66%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC--LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTRE 1099
            IGSGFF++VY V H   +  MA K+ K + +    ++E++L+  L+H NIL+F G C+  G    LTE+++ GN+ +L++     L W++RV +A +IA GL YLH + + HRDL+++N L+   +S+ N       Y AV+ DFGL   +   D   ++++ VG+PF+ APE L++E PY+  +DVFS+G++LCE+I  ++ DP+F+PRT  +GLDY     +  DCP    QLA +CC +    RP+     +++ + +  +      RE
Sbjct:   65 IGSGFFSEVYKVRHRASDQVMALKMNKLSSNRANMLREVQLMNRLSHPNILRFMGVCVQEGQLHALTEYINGGNLEQLLDSNK-FLSWASRVKLASEIAMGLAYLHSKGIFHRDLTSKNCLI---KSDENG------YTAVVGDFGLAEKIPSHDADGEKLAVVGSPFWMAPEVLRDE-PYNEKADVFSYGIILCEIIARIQADPDFLPRTENFGLDYHAFQHMVGDCPPDFLQLAFNCCNMDPKLRPSFPEIVKRLEDIQRRLKAEETERE 325

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BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: zgc:113162 (dual specificity testis-specific protein kinase 1-like [Source:NCBI gene;Acc:103045779])

HSP 1 Score: 176.022 bits (445), Expect = 6.467e-50
Identity = 93/260 (35.77%), Postives = 150/260 (57.69%), Query Frame = 2

Query:  266 KDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRAD----RMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPT 1030
            +DF  N ++IGSGFF+KVY V H      +  K+ K     +  V+EI LL+ L+H N++++ G C+       + E++  G +  L+ ++   L W  +V +A DI++G+ YLH + + HRDL+++N L+  T              AV+ DFGL   + ++ A+    +MS VG+ F+ APE L+ E PYD   DVFSFG++LCE++  +  DP  +PRT  YGLD +    + + CP+ + QL+  CC++   RRP+
Sbjct:   58 EDF--NTELIGSGFFSKVYKVMHSTTKKVLVVKIYKNDVDQDSIVREISLLQKLSHPNVVRYLGICVKEDKLYPILEYVSGGCLEELLARDDITLCWREKVELACDISRGMTYLHYKNIYHRDLNSKNCLIRVTPR---------GREAVVTDFGLAREVGELPANNPDRKMSLVGSAFWMAPEMLRGE-PYDRKVDVFSFGIMLCEILARIPADPEVLPRTRDYGLDVQAFSELVQGCPQRVLQLSASCCLMEAYRRPS 305

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BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000012250.2 (dual specificity testis-specific protein kinase 1-like [Source:NCBI gene;Acc:103038789])

HSP 1 Score: 170.244 bits (430), Expect = 9.007e-48
Identity = 91/261 (34.87%), Postives = 145/261 (55.56%), Query Frame = 2

Query:  287 DIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRAD--RMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKL-PIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVE 1060
            ++IGSGFF+KVY V H      M  K+ K     +  V+EI LL+ L+H NI+++ G C+       + E++  G +  L+ ++   L W  +V +A DI +G++YLH + + HRDL+++N L+  T              A++ DFGL   + ++ A   ++S VG+ F+ APE L+ E PYD   DVFSFG++LCE++  +  DP  +PRT  YGLD      +   CP+ +  LA  CC++   RRP+      ++ E
Sbjct:   63 ELIGSGFFSKVYKVMHNSTRKVMVVKIYKNDVDQDSIVREISLLQKLSHPNIVRYLGICVKEDKLYPILEYVSGGCLEELLARKDVPLCWREKVDLASDITRGMIYLHYKNIYHRDLNSKNCLIRVTPR---------GREALVTDFGLAREVVELPAKDRKLSLVGSAFWMAPEMLRGE-PYDRKVDVFSFGIVLCEILARIPADPEILPRTQDYGLDVSAFRKMVTGCPQQVLDLAASCCLLEAFRRPSFSELLDELSE 313

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BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: si:dkeyp-75h12.2 (dual specificity testis-specific protein kinase 1 [Source:NCBI gene;Acc:103036398])

HSP 1 Score: 177.178 bits (448), Expect = 1.979e-47
Identity = 93/250 (37.20%), Postives = 145/250 (58.00%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKD----VRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRP 1027
            IGSGFF++V+ V H +    MA K+     +    +KE++L+  L H NIL+F G C++ G    LTE+++ GN+ +L++ +   L WS R+ +  DIA+GL YLH + + HRDL+++N L+              +  AV+ DFGL   + D     +   ++ VG+P++ APE L+ E  YD   DVF+FG++LCE+I  ++ DP+F+PRT  +GLD      + RDCP     LA+ CC +    RP
Sbjct:   47 IGSGFFSEVFKVKHRITGQVMALKMNTLASNRANMLKEVQLMNRLCHPNILRFVGVCVHEGHLHALTEYINGGNLEQLLDSDV-HLSWSVRMGLGLDIARGLQYLHSKGIFHRDLTSKNCLVRWDNG---------ACTAVVGDFGLAEKIPDYSDGSQKQPLAIVGSPYWMAPEVLRGEL-YDEKVDVFAFGIILCEVIGRIQADPDFLPRTEDFGLDVDAFQHMVRDCPPAFFNLAVTCCSMRAQCRP 285

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BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: zgc:113162 (dual specificity testis-specific protein kinase 1-like [Source:NCBI gene;Acc:103045779])

HSP 1 Score: 155.221 bits (391), Expect = 1.799e-42
Identity = 82/242 (33.88%), Postives = 135/242 (55.79%), Query Frame = 2

Query:  320 YIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRAD----RMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKL-PIKRDCPKWIHQLALDCCVISISRRPT 1030
            Y V H      +  K+ K     +  V+EI LL+ L+H N++++ G C+       + E++  G +  L+ ++   L W  +V +A DI++G+ YLH + + HRDL+++N L+  T              AV+ DFGL   + ++ A+    +MS VG+ F+ APE L+ E PYD   DVFSFG++LCE++  +  DP  +PRT  YGLD +    + + CP+ + QL+  CC++   RRP+
Sbjct:   52 YHVMHSTTKKVLVVKIYKNDVDQDSIVREISLLQKLSHPNVVRYLGICVKEDKLYPILEYVSGGCLEELLARDDITLCWREKVELACDISRGMTYLHYKNIYHRDLNSKNCLIRVTPR---------GREAVVTDFGLAREVGELPANNPDRKMSLVGSAFWMAPEMLRGE-PYDRKVDVFSFGIMLCEILARIPADPEVLPRTRDYGLDVQAFSELVQGCPQRVLQLSASCCLMEAYRRPS 283

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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007356.1 (pep scaffold:Pmarinus_7.0:GL476565:29629:68809:1 gene:ENSPMAG00000006641.1 transcript:ENSPMAT00000007356.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 135.961 bits (341), Expect = 1.347e-37
Identity = 72/181 (39.78%), Postives = 114/181 (62.98%), Query Frame = 2

Query:  395 FVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPL-LDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC-----LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRT 919
             ++E++L+  L+H NIL + G C++ G    LTE+++ GN+ +L++   P+ L W  R+ +A DIA+GL YLH + V HRDL+++N L+    S          Y  ++ DFGL       N K  R +R++ VG+PF+ APE L+ E  YD + DVFSFG++LCE+I  ++ DP+++PRT
Sbjct:   13 MLREVQLMNRLSHPNILGYMGVCVHEGQLHALTEYVNGGNLEQLLDS--PVYLSWLVRIKLALDIARGLKYLHSRGVFHRDLTSKNCLIKYDDS---------GYTGIVGDFGLAETIPKCNEKGER-ERLAVVGSPFWMAPEVLRGEI-YDETIDVFSFGIILCEIIARVQADPDYLPRT 180

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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006670.1 (pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene:ENSPMAG00000006016.1 transcript:ENSPMAT00000006670.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 97.0561 bits (240), Expect = 4.497e-22
Identity = 74/261 (28.35%), Postives = 120/261 (45.98%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEK-EGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRM-STVGNPF---YTAPENLKNESPYDYSSDVFSFGMLLCELIT-------GLKNDPNFIPRTNKYGLDYKKLPIKRDCPKWIHQLALDCCVISISRRPTMKS 1039
            +G+G F +V+              + + T   + F++E +L+K L H  +++ Y  C        +TE +  G+++  ++  EG  LD    V +A  +A G+ YL  Q  IHRDL+A NIL+ +  +              +ADFGL   +K    D   + VG+ F   +TAPE   N + +   SDV+SFG+LL E+IT       G  N          Y     ++P    CP+  + L L+C  +    RPT ++
Sbjct:  120 LGAGQFGEVWQGLWNKTTPVAIKTLKQGTMDRDDFLREAQLMKRLRHPKLIQLYAVCTQEEPIYIITELMSNGSLANYLQTPEGRSLDLVELVDMAAQVAAGMAYLEAQNYIHRDLAARNILVAEHNA------------CKVADFGLARVIKMSNEDEYEARVGSKFPIKWTAPEA-ANYNRFSIKSDVWSFGVLLHEIITYGKLPYPGQTNAEVLAAVDRGY-----RMPCPPGCPQAFYDLMLECWNVDDQARPTFET 362

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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004129.1 (pep scaffold:Pmarinus_7.0:GL490249:304:4500:1 gene:ENSPMAG00000003774.1 transcript:ENSPMAT00000004129.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 92.0485 bits (227), Expect = 5.284e-21
Identity = 72/249 (28.92%), Postives = 114/249 (45.78%), Query Frame = 2

Query:  287 DIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKR--DCPKWIHQLALDCCVISISRRP 1027
            +++G G F +VY          +A K+ +   S + F+KE+K + S  H+N+L+ Y  C     +  +TE + YGNM   + + G  L    R+++A  IA G+ YL  +  IH DL+  NIL+ +                 +ADFGL   +K+   D    V    + APE L  +  +   SDV+SFG+LL EL T  K     + +     L      +KR   CP  ++ +   C      +RP
Sbjct:   27 NLLGRGNFGEVY-EGRWNDTTDVAIKIVRTNSSFDTFMKEVKTMISFKHENVLQIYAVCKEKWPYWIVTELVPYGNMLHYLGRFGHELSEVERLYMAFGIASGMAYLSKKRCIHCDLAGRNILMGQHNI------------CKVADFGLSHKLKEEYYDATGHVVPFQWMAPEVLI-QLKFTRKSDVWSFGVLLYELFTDGKRPYADMDKQQVQDLIKCGGRLKRPDACPNVVYHIMQRCWNFEHRKRP 261

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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: hck (HCK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-090313-72])

HSP 1 Score: 94.3597 bits (233), Expect = 6.483e-21
Identity = 76/259 (29.34%), Postives = 124/259 (47.88%), Query Frame = 2

Query:  293 IGSGFFAKVYI-VYHVVLNLKMAFKVPKP-TQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNM-SRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPF-YTAPENLKNESPYDYSSDVFSFGMLLCELIT-------GLKNDPNFIPRTNKYGLDYKKLPIKRDCPKWIHQLALDCCVISISRRPTMK 1036
            +G+G F +V++ +Y+     K+A K  KP + S   F+ E  L+K+L H  +++ Y       ++  +TEF++ G++   L   EG  L     + +A  IA+G+ ++  +  IHRDL A NIL+        NE +     + IADFGL   ++D           P  +TAPE + N   +   SDV+SFG+LL E+IT       G+ N          Y     ++P     PK ++ + +DC       RPT +
Sbjct:  188 LGAGQFGEVWMGIYNN--RTKVAIKTMKPGSMSPEAFLDEANLMKTLQHPRLVRLYAVVTQEPIY-IVTEFMENGSLLDYLKSTEGSTLPMPKMIDMAAQIAEGMAFIERKNYIHRDLRAANILV--------NEQLA----SKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAI-NYGSFSIKSDVWSFGILLTEIITFGRIPYPGMSNSDVIRQLERGY-----RMPCPEQAPKQLYGVMMDCWKERPEERPTFE 425

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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: clul1 (clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GENE-031118-57])

HSP 1 Score: 92.8189 bits (229), Expect = 2.281e-20
Identity = 83/284 (29.23%), Postives = 126/284 (44.37%), Query Frame = 2

Query:  200 IIPKRNPVAIGFANDINLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKP-TQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLI-EKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPF-YTAPENLKNESPYDYSSDVFSFGMLLCELIT-GLKNDPNFIPRTNKYGLDYK-KLPIKRDCPKWIHQLALDCCVISISRRPTMK 1036
            + P   P   G A D      D   K  L + G G F +V+         K+A K  KP T S   F++E +++K L HD +++ Y       ++  +TEF+  G++   + E +G  L     V +A  IA G+ Y+     IHRDL A NIL+              +    IADFGL   ++D           P  +TAPE       +   SDV+SFG+LL EL+T G    P  + R     ++   ++P    CP+ +H+L + C       RPT +
Sbjct:  184 VCPNEKPQTQGLARDAWEMPRD-SLKLELKL-GQGCFGEVWAGTWNGTT-KVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEEPIY-IVTEFMSKGSLLDFLKEGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGD------------NLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAAMF-GRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPPSCPESLHELMMQCWKKDPEERPTFE 450

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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631])

HSP 1 Score: 102.449 bits (254), Expect = 3.925e-23
Identity = 76/269 (28.25%), Postives = 125/269 (46.47%), Query Frame = 2

Query:  287 DIIGSGFFAKVYIVYHVVLNLKMAFK---VPKPTQ-------SINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEG----PLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADR-MSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNF--IPRTNKYGLDYKKLPIKRDCPKWIHQLA---LDCCV-ISISRRPT 1030
            ++IG G F  VY+  +V     MA K   VPK +        ++     E+  LK L+H NI+++ G    N ++    E++  G++  LI   G    PL+      H+   + KGL YLH + ++HRD+ A+N+LL       + + +       I+DFG+    KD+ ++  M+  G  F+ APE +  +  Y    D++S G ++ E+  G +   N   +    K G      PI  D    I Q+    LD C  I+  +RPT
Sbjct: 1179 EMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIK-----HLTTQVLKGLAYLHSKGILHRDMKADNLLL-------DQDGI-----CKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPT 1430

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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CLA4 (Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242])

HSP 1 Score: 93.5893 bits (231), Expect = 2.159e-20
Identity = 57/181 (31.49%), Postives = 90/181 (49.72%), Query Frame = 2

Query:  395 FVKEIKLLKSLNHDNILKFYGACL-YNGVFGYLTEFLDYGNMSRLIE-------KEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITG----LKNDP 901
             V EI ++K   H NI+ F  A L  +     + EF++ G+++ +IE          PL +     +I  +  +GL +LHD+ +IHRD+ ++N+LL                R  I DFG C  + D R+ R + VG P++ APE +K    YD   DV+S G++  E++ G    L  DP
Sbjct:  607 IVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTE-PQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDT------------RARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQRE-YDEKIDVWSLGIMTIEMLEGEPPYLNEDP 773

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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999])

HSP 1 Score: 88.5817 bits (218), Expect = 7.307e-19
Identity = 54/207 (26.09%), Postives = 102/207 (49.28%), Query Frame = 2

Query:  278 SNLDIIGSGFFAKVYIVYHVVLNLKMAFKV----PKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITG 886
            +NL  IG G    VY  Y +  N+ +A K      +P + +   + EI ++K   H NI+ F  + +  G    + E+++ G+++ ++     +L       +  +   GL +LH + V+HRD+ ++NILL          S+    +  + DFG C  + ++   R + VG P++ APE +  +  Y    D++S G+++ E+I G
Sbjct:  621 ANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKEL--IINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHC--ILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILL----------SMEGDIK--LTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKE-YGPKVDIWSLGIMIIEMIEG 810

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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: SKM1 (Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473])

HSP 1 Score: 86.2705 bits (212), Expect = 3.006e-18
Identity = 60/206 (29.13%), Postives = 105/206 (50.97%), Query Frame = 2

Query:  332 HVVLNLKMAFKVPKPTQSINK--FVKEIKLLKSLNHDNILKFYGACLYNGV----------FGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITG----LKNDP 901
            H V+  ++A K  + ++   K   + E+ ++     +NI+ F  A + +             G LT+ LD    S   E   PL + +   +I ++  +GL +LH++ +IHRD+ ++NILL       N++ ++      I DFG C+ + + R+ R + VG P++ APE + N+  YD   DV+S G++L E+I G    L  DP
Sbjct:  396 HRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNE-NQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILL-------NSQGLVK-----ITDFGFCVELTEKRSKRATMVGTPYWMAPE-IVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDP 587

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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072])

HSP 1 Score: 78.9518 bits (193), Expect = 8.106e-16
Identity = 66/217 (30.41%), Postives = 103/217 (47.47%), Query Frame = 2

Query:  260 SDKDFKSNL-DIIGSGFFAKVYIVYHVVLNLKMAFK--VPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDP 901
            S+K  + +L  +IG G +  VY   +   +  +A K  V +  + +N  + EI LLK+LNH+NI+K++G    +     L E+   G++ RLI +    L  +           GL YLH + VIHRD+ A NILL    +              +ADFG+      V +  ++  G   + APE L N       SD++S G  + E++T  KN P
Sbjct:   19 SEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNT------------VKLADFGVS---TIVNSSALTLAGTLNWMAPEILGNRGASTL-SDIWSLGATVVEMLT--KNPP 217

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BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO46137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM9])

HSP 1 Score: 166.777 bits (421), Expect = 2.602e-44
Identity = 88/272 (32.35%), Postives = 145/272 (53.31%), Query Frame = 2

Query:  242 DINLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKI 1054
            D +L +   DF  NL  + +GFF +++   H +    M  K           +KE+  L+ L+H NI++F G C+ +     +TEF++ GN+  L+      L+W+ RV++A DIA G+ +LH +  +HRDL+++N L+     E            ++AD GL   + D     ++TVG+P+  APE L+ E  Y+  +DVFS+G++LCE+I  +  DP  +PRT  +GLD +K   +  DCP      A+ CC +    RP+  S  + +
Sbjct:   88 DASLVFDINDF--NLYRLANGFFGEIFKAEHKITKKTMVIKEETHCNEDCSLLKEVDFLRRLSHPNIVRFIGICIKDNKVSLITEFVNGGNLEELLMNHEETLNWATRVYLARDIASGMAFLHQKRFLHRDLTSKNCLIKIANGE---------RYGIVADLGLATELPDGEEGIINTVGSPYNMAPEVLRGEM-YNGKADVFSYGIILCEIIGRVLADPEELPRTGAFGLDVEKFSTMVGDCPIEFVHTAICCCQMDPKSRPSFMSTVKHL 347

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BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO44183 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWK9])

HSP 1 Score: 145.206 bits (365), Expect = 3.361e-37
Identity = 85/278 (30.58%), Postives = 144/278 (51.80%), Query Frame = 2

Query:  287 DIIGSGFFAKVYIVYHVVLNLKMAFK--VPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC-LNMKD--------VRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIK--RDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDL 1081
            ++IG GFF +V  V H      M  K  +    ++   F+KE+ LLKSL H N+L F G          + E++  G + R+++ +   L W+ +V I+ DIA G+ YLH+  V+HRDL++ N L+H  +  T           V+ADFGL  L+ ++            R + VG P++ APE + N   YD+  D+F+F ++ CE+I  ++ DP+++PR   + +D     +K    CP   ++LA  C  +   +RP  ++  + +  + IY+ L
Sbjct:  324 EVIGRGFFGQVMKVTHKTTGEVMVLKELINYDDEAKAGFLKEVALLKSLQHPNVLHFIGILYKGKTLNLIVEYIPGGTLQRVLKDKSRPLSWAQKVKISRDIAAGMAYLHEMNVMHRDLNSNNCLVHNDEEMT----------VVVADFGLARLHQEEPLSHAIPPAPKKRYTVVGTPYWMAPE-MFNGRDYDHRVDIFAFCIVACEIIGRVEADPDYLPRKKDFTVDEDSFRMKFCAGCPAVFYKLAFLCGHLDPDKRPPFETVREWL--DAIYLHL 588

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO36442 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIN7])

HSP 1 Score: 112.079 bits (279), Expect = 2.047e-26
Identity = 82/276 (29.71%), Postives = 134/276 (48.55%), Query Frame = 2

Query:  284 LDIIGSGFFAKVYIVYHVVLNLKMAFKVPKP------TQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEK------EGPLLDWSNRVHIAEDIAKGLVYLHDQF---VIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYG--LDYKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVE 1060
            +D+IG G F KVY    +  + ++A KV +       TQ+++   KE ++   L H NI+   G  L       + E+   G +SR +           LL+W      A  IA+G+ YLH +    ++HRDL + NILLH   +E++  +++      I DFGL   + +    RMS  G   + APE ++  + + ++SDV+S+G++L EL+TG     +       YG  ++   LPI   CP+    L  DC      +RPT K+  + + E
Sbjct:   78 IDVIGVGAFGKVY--RGIWRDEEVAVKVARTDNYEDFTQTLDSVKKEARIFSMLRHQNIVGLLGVSLEQPNLCLVLEYARGGALSRALSSYNRNIPPSVLLNW------AIQIAQGMFYLHSEAPVTIVHRDLKSGNILLHYKINESDFNNILK-----ITDFGLAREIANT--TRMSAAGTYAWMAPEVIRTNT-FSFASDVWSYGVVLWELLTGQVPYKDVEALAVAYGVAMNSLTLPIPTTCPEVFKNLMADCWNQDPHKRPTFKAVLEALEE 337

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO42845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A9])

HSP 1 Score: 93.5893 bits (231), Expect = 5.466e-21
Identity = 64/231 (27.71%), Postives = 108/231 (46.75%), Query Frame = 2

Query:  284 LDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKRDCPKW 976
            L+ +G G +  V+   H      +A K       + + +KEI +++  +   ++K+YG+   N     + E+   G++S L++     L       + +   KGL YLH +  IHRD+ A NILL       N+E       A +ADFG+   + D  A R + +G PF+ APE ++ E  YD  +D++S G+   E+  G     +  P    + +  K  P  RD  +W
Sbjct:   27 LEKLGEGSYGSVFKAMHKESGQVVAIKQVPVDTDLQEIIKEISMMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDLMKIRNKTLTEEEIKCVLKYTLKGLEYLHLRRKIHRDIKAGNILL-------NSEG-----HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQ-EVGYDCLADIWSLGITAMEMAEGKPPYADIHPMRAIFMIPTKPPPTFRDPGQW 244

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO47195 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN18])

HSP 1 Score: 91.2781 bits (225), Expect = 2.209e-20
Identity = 74/259 (28.57%), Postives = 120/259 (46.33%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFK-VPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGN-MSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLC-LNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELIT-GLKNDPNFIPRTNKYGLDYK-KLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKI 1054
            +G G + +VY       N  +A K + + T  + +F+KE  ++K + H N+++  G C     F  +TEF+  GN +  L   +G  LD    +++A  +   + YL     IHRDL+A N L+       NN          +ADFGL  L  +D+            +TAPE L + + +   SDV++FG+LL EL T G+   P          LD   ++P    CP  ++ L   C     + RP+ K  ++K+
Sbjct:   20 LGGGQYGEVYEGTWKKYNKTVAVKTLREETMEVEEFLKEASVMKGIKHQNLVQLLGVCTREPPFYIITEFMMNGNLLDYLRSPKGKDLDAVTLMYMATQVGSAMSYLESMNFIHRDLAARNCLVGD-----NN-------LVKVADFGLSRLVSEDIYTAHQGAKFPIKWTAPEALAHNT-FSIKSDVWAFGILLWELATYGMSPYPGIDLSQVYDKLDGGYRMPCPEGCPPEVYSLMQTCWCWDPNSRPSFKEIHEKL 265

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: si:dkeyp-75h12.2 (testis associated actin remodelling kinase 1 [Source:NCBI gene;Acc:101172935])

HSP 1 Score: 176.407 bits (446), Expect = 2.804e-47
Identity = 99/280 (35.36%), Postives = 160/280 (57.14%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRAD----RMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTR-EPKKKI 1114
            IG+GFF++V+ V H V    MA K+     +    ++E++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++ E   L WS R+ +A DIA+GL YLH + + HRDL+++N L+       +         AV+ DFGL   + D   D     ++ VG+P++ APE L+ E  Y+   DVF++G++LCE+I  ++ DP+ +PRT  +GLD +    +  DCP    ++A+ CC ++   RP+    + +IV     I   R  R EP  KI
Sbjct:   57 IGAGFFSEVFKVQHRVTGQVMALKMNILASNRANMLREVQLMNRLSHPNILRFIGVCVHEGQLHALTEYINGGNLEQLLDSEV-YLSWSVRLSLALDIARGLKYLHSKGIFHRDLTSKNCLVRWEGDVCS---------AVVGDFGLAEKIPDYSEDDVQEPLAVVGSPYWMAPEVLRGEI-YNEKVDVFAYGIILCEIIARIQADPDILPRTEDFGLDVEAFQRMVEDCPLDFLEMAISCCNMNAELRPS----FAQIVAELEKIQAERAQRHEPPVKI 321

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: si:ch211-113e8.3 (dual specificity testis-specific protein kinase 2 [Source:NCBI gene;Acc:101158994])

HSP 1 Score: 176.022 bits (445), Expect = 2.860e-47
Identity = 89/251 (35.46%), Postives = 146/251 (58.17%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADR----MSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPT 1030
            IGSGFF++V+ V H +    MA K+     +    ++E++L+  L H NIL+F G C++ G    LTE+++ GN+ +L++ +   L W  R+ +++DIA+GL YLH + + HRDL+++N L+               + AV+ DFGL   + D         ++ VG+P++ APE L+ E  Y+   DVF+FG++LCE+I  ++ DP+ +PRT  +GLD +    +  DCP     LA+ CC +S   RP+
Sbjct:   56 IGSGFFSEVFKVQHRITGQVMALKMNTLASNKANMLREVQLMNRLCHPNILRFLGVCVHEGQLHALTEYINGGNLEQLLDSDL-FLSWGVRLGLSQDIARGLQYLHSKGIFHRDLTSKNCLVRCENGR---------FTAVVGDFGLAEKIPDYSGPEEKQPLAVVGSPYWMAPEVLRGEL-YNEKVDVFAFGIILCEIIARIEADPDVLPRTEDFGLDVETFRNMIGDCPAAFFGLAVSCCNMSAESRPS 295

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: si:dkeyp-75h12.2 (testis associated actin remodelling kinase 1 [Source:NCBI gene;Acc:101172935])

HSP 1 Score: 176.022 bits (445), Expect = 3.082e-47
Identity = 99/280 (35.36%), Postives = 160/280 (57.14%), Query Frame = 2

Query:  293 IGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRAD----RMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTR-EPKKKI 1114
            IG+GFF++V+ V H V    MA K+     +    ++E++L+  L+H NIL+F G C++ G    LTE+++ GN+ +L++ E   L WS R+ +A DIA+GL YLH + + HRDL+++N L+       +         AV+ DFGL   + D   D     ++ VG+P++ APE L+ E  Y+   DVF++G++LCE+I  ++ DP+ +PRT  +GLD +    +  DCP    ++A+ CC ++   RP+    + +IV     I   R  R EP  KI
Sbjct:   53 IGAGFFSEVFKVQHRVTGQVMALKMNILASNRANMLREVQLMNRLSHPNILRFIGVCVHEGQLHALTEYINGGNLEQLLDSEV-YLSWSVRLSLALDIARGLKYLHSKGIFHRDLTSKNCLVRWEGDVCS---------AVVGDFGLAEKIPDYSEDDVQEPLAVVGSPYWMAPEVLRGEI-YNEKVDVFAYGIILCEIIARIQADPDILPRTEDFGLDVEAFQRMVEDCPLDFLEMAISCCNMNAELRPS----FAQIVAELEKIQAERAQRHEPPVKI 317

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: tesk2 (dual specificity testis-specific protein kinase 2 [Source:NCBI gene;Acc:101168985])

HSP 1 Score: 150.984 bits (380), Expect = 2.414e-39
Identity = 91/268 (33.96%), Postives = 147/268 (54.85%), Query Frame = 2

Query:  287 DIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP-IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVEN--EIYIDL 1081
            + IGSGFF+ V+ V H   +  MA K+ K + +    ++E++L+  L H NIL+F G C++ G    LTE+++ GN+ +L+E     L W +RV +A DIA G+ YLH + + HRDL+++N L+   + + N       Y AV+ DF        VR          F+     L+        +DVFS+G+++CE+I  ++ DP+F+PRT  +GLDY     +  DCP    QLA +CC +     P ++ ++Q IV +  E+ + L
Sbjct:   57 EWIGSGFFSDVFKVRHRASDQVMALKMNKLSSNRANMLREVQLMNRLCHPNILRFKGVCVHEGQLHALTEYINGGNLEQLLESNN-HLSWLSRVKLACDIASGVAYLHSKGIFHRDLTSKNCLI---KCDDNG------YTAVVGDFA------PVR----------FHAVLLCLQ--------ADVFSYGIVMCEIIARVQADPDFLPRTENFGLDYHTFQHMVGDCPSDFLQLAFNCCNMD----PKLRPSFQDIVRHLEEVLVQL 286

[Close]

BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: limk1a (LIM domain kinase 1-like [Source:NCBI gene;Acc:101168972])

HSP 1 Score: 146.747 bits (369), Expect = 4.547e-37
Identity = 86/290 (29.66%), Postives = 144/290 (49.66%), Query Frame = 2

Query:  287 DIIGSGFFAKVYIVYH----VVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRAD------------------RMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLP---IKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDL 1081
            +++G G F +   V H     V+ +K   +    TQ    F+KE+K+++ L+H N+LKF G    +    ++ E++  G +  +I+K      W+ RV  A+DIA G+ YLH   +IHRDL++ N L+ +  +             V+ADFGL   M D + D                  R + VGNP++ APE +  +S YD   D+FSFG++LCE+I  +  DP+++PR   +GL+           DCP     +A  CC +   +RP      + +   ++++D+
Sbjct:  356 EVLGKGCFGQAIKVTHRETGEVMVMKELIRFDDETQ--RTFLKEVKVMRCLDHPNVLKFIGVLYKDKRLNFIAEYIKGGTLREIIKKMDSNYPWNQRVSFAKDIAAGMAYLHSMNIIHRDLNSYNCLVREDNT------------VVVADFGLSRLMVDDKQDESLLQGKLSGLKRHDRRKRYTVVGNPYWMAPEMIHGKS-YDERVDIFSFGIMLCEIIGRVNADPDYLPRATDFGLNISGFLEHFCPPDCPPAFFPMAAVCCDLDADKRPPFLKLEELLENLKMHLDI 630

[Close]

BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000023685.1 (SMESG000023685.1)

HSP 1 Score: 797.734 bits (2059), Expect = 0.000e+0
Identity = 399/400 (99.75%), Postives = 400/400 (100.00%), Query Frame = 2

Query:   98 MKYHNGTKMPLNCFKNHSLSIDNKTMSNTNPNSEIIPKRNPVAIGFANDINLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHSYNVNNQFRGAXXXXXXXXXXXXLLRKLCKNNSKDDNVSSPLSPILNDCQKIYRHNS 1297
            MKYHNGTKMPLNCFKNHSLSIDNKTMSNTNPNSEIIPKRNPVAIGFANDINLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHI+EDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHSYNVNNQFRGASMSISQDYYSSSLLRKLCKNNSKDDNVSSPLSPILNDCQKIYRHNS
Sbjct:    1 MKYHNGTKMPLNCFKNHSLSIDNKTMSNTNPNSEIIPKRNPVAIGFANDINLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHISEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHSYNVNNQFRGASMSISQDYYSSSLLRKLCKNNSKDDNVSSPLSPILNDCQKIYRHNS 400

[Close]

BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000023685.1 (SMESG000023685.1)

HSP 1 Score: 780.4 bits (2014), Expect = 0.000e+0
Identity = 391/392 (99.74%), Postives = 392/392 (100.00%), Query Frame = 2

Query:  122 MPLNCFKNHSLSIDNKTMSNTNPNSEIIPKRNPVAIGFANDINLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHSYNVNNQFRGAXXXXXXXXXXXXLLRKLCKNNSKDDNVSSPLSPILNDCQKIYRHNS 1297
            MPLNCFKNHSLSIDNKTMSNTNPNSEIIPKRNPVAIGFANDINLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHI+EDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHSYNVNNQFRGASMSISQDYYSSSLLRKLCKNNSKDDNVSSPLSPILNDCQKIYRHNS
Sbjct:    1 MPLNCFKNHSLSIDNKTMSNTNPNSEIIPKRNPVAIGFANDINLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHISEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKRDCPKWIHQLALDCCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHSYNVNNQFRGASMSISQDYYSSSLLRKLCKNNSKDDNVSSPLSPILNDCQKIYRHNS 392

[Close]

BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000004938.1 (SMESG000004938.1)

HSP 1 Score: 101.293 bits (251), Expect = 5.201e-22
Identity = 64/219 (29.22%), Postives = 110/219 (50.23%), Query Frame = 2

Query:  236 ANDINLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQ--SINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITG 886
            + DI   Y   D    + ++G G F  V+    +   +K+A K    +Q   +    +EI L   L+H NI+ + G+    GVF  + E +  G+++ L++K G L + +   + +  I +GL YLHD  ++HRD+  +N+L++           MY+    I+DFG    + D+     +  G   Y APE +K  S Y + +DV+SFG  + E++TG
Sbjct:  648 SEDIQFEYEYDDNDQRI-VLGRGTFGTVFAGRELTKQIKIAIKEVNESQIKEVQPLHEEIWLHSRLSHRNIVSYLGSRSEKGVFKIIMEQVPGGSLTSLLKKNGALTEETTSYY-SNQILEGLKYLHDNRIMHRDIKGDNVLVN-----------MYNGILKISDFGTSKRLGDIMQRASTFTGTMQYMAPELIKGPSGYGFPADVWSFGCTVIEMLTG 853

[Close]

BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000004938.1 (SMESG000004938.1)

HSP 1 Score: 101.293 bits (251), Expect = 5.366e-22
Identity = 64/219 (29.22%), Postives = 110/219 (50.23%), Query Frame = 2

Query:  236 ANDINLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQ--SINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITG 886
            + DI   Y   D    + ++G G F  V+    +   +K+A K    +Q   +    +EI L   L+H NI+ + G+    GVF  + E +  G+++ L++K G L + +   + +  I +GL YLHD  ++HRD+  +N+L++           MY+    I+DFG    + D+     +  G   Y APE +K  S Y + +DV+SFG  + E++TG
Sbjct:  648 SEDIQFEYEYDDNDQRI-VLGRGTFGTVFAGRELTKQIKIAIKEVNESQIKEVQPLHEEIWLHSRLSHRNIVSYLGSRSEKGVFKIIMEQVPGGSLTSLLKKNGALTEETTSYY-SNQILEGLKYLHDNRIMHRDIKGDNVLVN-----------MYNGILKISDFGTSKRLGDIMQRASTFTGTMQYMAPELIKGPSGYGFPADVWSFGCTVIEMLTG 853

[Close]

BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000004938.1 (SMESG000004938.1)

HSP 1 Score: 101.293 bits (251), Expect = 5.375e-22
Identity = 64/219 (29.22%), Postives = 110/219 (50.23%), Query Frame = 2

Query:  236 ANDINLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQ--SINKFVKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPLLDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVMYSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDVFSFGMLLCELITG 886
            + DI   Y   D    + ++G G F  V+    +   +K+A K    +Q   +    +EI L   L+H NI+ + G+    GVF  + E +  G+++ L++K G L + +   + +  I +GL YLHD  ++HRD+  +N+L++           MY+    I+DFG    + D+     +  G   Y APE +K  S Y + +DV+SFG  + E++TG
Sbjct:  648 SEDIQFEYEYDDNDQRI-VLGRGTFGTVFAGRELTKQIKIAIKEVNESQIKEVQPLHEEIWLHSRLSHRNIVSYLGSRSEKGVFKIIMEQVPGGSLTSLLKKNGALTEETTSYY-SNQILEGLKYLHDNRIMHRDIKGDNVLVN-----------MYNGILKISDFGTSKRLGDIMQRASTFTGTMQYMAPELIKGPSGYGFPADVWSFGCTVIEMLTG 853

The following BLAST results are available for this feature:

BLAST of Protein kinase domain-containing protein vs. Ensembl Human
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
BLAST of Protein kinase domain-containing protein vs. TrEMBL
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST

BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TESK2	1.578e-52	36.69	testis associated actin remodelling kinase 2 [Sour...	[more]
TESK1	2.041e-49	33.78	testis associated actin remodelling kinase 1 [Sour...	[more]
TESK1	2.041e-49	33.78	testis associated actin remodelling kinase 1 [Sour...	[more]
TESK2	4.909e-45	39.62	testis associated actin remodelling kinase 2 [Sour...	[more]
LIMK1	3.062e-37	32.22	LIM domain kinase 1 [Source:HGNC Symbol;Acc:HGNC:6...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
C24A1.3	3.619e-23	29.96	pep chromosome:WBcel235:III:692547:696456:-1 gene:...	[more]
src-1	1.208e-22	29.46	Tyrosine protein-kinase src-1 [Source:UniProtKB/S...	[more]
src-1	1.208e-22	29.46	Tyrosine protein-kinase src-1 [Source:UniProtKB/S...	[more]
src-1	1.514e-22	29.46	Tyrosine protein-kinase src-1 [Source:UniProtKB/S...	[more]
src-1	1.514e-22	29.46	Tyrosine protein-kinase src-1 [Source:UniProtKB/S...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cdi	4.499e-49	34.91	gene:FBgn0004876 transcript:FBtr0305321	[more]
cdi	1.297e-48	35.14	gene:FBgn0004876 transcript:FBtr0083716	[more]
LIMK1	9.425e-35	30.17	gene:FBgn0283712 transcript:FBtr0301831	[more]
LIMK1	1.039e-34	30.17	gene:FBgn0283712 transcript:FBtr0073661	[more]
LIMK1	1.714e-34	30.17	gene:FBgn0283712 transcript:FBtr0073659	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tesk2	1.656e-54	36.86	testis associated actin remodelling kinase 2 [Sour...	[more]
tesk2	1.656e-54	36.86	testis associated actin remodelling kinase 2 [Sour...	[more]
si:dkeyp-75h12.2	1.651e-48	35.36	si:dkeyp-75h12.2 [Source:ZFIN;Acc:ZDB-GENE-030131-...	[more]
si:dkeyp-75h12.2	1.651e-48	35.36	si:dkeyp-75h12.2 [Source:ZFIN;Acc:ZDB-GENE-030131-...	[more]
zgc:113162	5.384e-48	35.00	zgc:113162 [Source:ZFIN;Acc:ZDB-GENE-050522-530]	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cnksr1	2.669e-54	39.36	connector enhancer of kinase suppressor of Ras 1 [...	[more]
cnksr1	2.835e-54	36.30	connector enhancer of kinase suppressor of Ras 1 [...	[more]
cnksr1	3.254e-54	36.30	connector enhancer of kinase suppressor of Ras 1 [...	[more]
cnksr1	3.698e-54	36.30	connector enhancer of kinase suppressor of Ras 1 [...	[more]
cnksr1	4.461e-54	39.75	connector enhancer of kinase suppressor of Ras 1 [...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Tesk2	1.521e-53	36.36	testis-specific kinase 2 [Source:MGI Symbol;Acc:MG...	[more]
Tesk1	9.347e-50	34.45	testis specific protein kinase 1 [Source:MGI Symbo...	[more]
Tesk2	3.971e-45	35.38	testis-specific kinase 2 [Source:MGI Symbol;Acc:MG...	[more]
Limk1	2.458e-37	32.22	LIM-domain containing, protein kinase [Source:MGI ...	[more]
Limk1	3.778e-37	32.22	LIM-domain containing, protein kinase [Source:MGI ...	[more]

BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8VCT9\|TESK2_MOUSE	1.064e-52	36.36	Dual specificity testis-specific protein kinase 2 ...	[more]
sp\|Q924U5\|TESK2_RAT	3.556e-52	37.45	Dual specificity testis-specific protein kinase 2 ...	[more]
sp\|Q96S53\|TESK2_HUMAN	7.577e-52	36.69	Dual specificity testis-specific protein kinase 2 ...	[more]
sp\|O70146\|TESK1_MOUSE	6.538e-49	34.45	Dual specificity testis-specific protein kinase 1 ...	[more]
sp\|Q15569\|TESK1_HUMAN	9.800e-49	33.78	Dual specificity testis-specific protein kinase 1 ...	[more]

BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1E1XDE3	2.814e-54	37.69	Putative tyrosine kinase specific for activated gt...	[more]
A0A0P4W4F0	4.079e-53	38.29	Protein kinase domain-containing protein OS=Scylla...	[more]
A0A224YTC1	5.775e-53	37.31	Center divider OS=Rhipicephalus zambeziensis OX=60...	[more]
A0A131YC96	5.775e-53	37.31	Center divider OS=Rhipicephalus appendiculatus OX=...	[more]
A0A4W3I2H1	4.722e-52	40.16	Protein kinase domain-containing protein OS=Callor...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tesk2	4.835e-55	37.13	testis associated actin remodelling kinase 2 [Sour...	[more]
zgc:113162	6.467e-50	35.77	dual specificity testis-specific protein kinase 1-...	[more]
ENSAMXT00000012250.2	9.007e-48	34.87	dual specificity testis-specific protein kinase 1-...	[more]
si:dkeyp-75h12.2	1.979e-47	37.20	dual specificity testis-specific protein kinase 1 ...	[more]
zgc:113162	1.799e-42	33.88	dual specificity testis-specific protein kinase 1-...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000007356.1	1.347e-37	39.78	pep scaffold:Pmarinus_7.0:GL476565:29629:68809:1 g...	[more]
ENSPMAT00000006670.1	4.497e-22	28.35	pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene...	[more]
ENSPMAT00000004129.1	5.284e-21	28.92	pep scaffold:Pmarinus_7.0:GL490249:304:4500:1 gene...	[more]
hck	6.483e-21	29.34	HCK proto-oncogene, Src family tyrosine kinase [So...	[more]
clul1	2.281e-20	29.23	clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
BCK1	3.925e-23	28.25	MAPKKK acting in the protein kinase C signaling pa...	[more]
CLA4	2.159e-20	31.49	Cdc42p-activated signal transducing kinase; member...	[more]
STE20	7.307e-19	26.09	Cdc42p-activated signal transducing kinase; involv...	[more]
SKM1	3.006e-18	29.13	Member of the PAK family of serine/threonine prote...	[more]
CDC15	8.106e-16	30.41	Protein kinase of the Mitotic Exit Network; locali...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46137	2.602e-44	32.35	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44183	3.361e-37	30.58	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36442	2.047e-26	29.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42845	5.466e-21	27.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47195	2.209e-20	28.57	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:dkeyp-75h12.2	2.804e-47	35.36	testis associated actin remodelling kinase 1 [Sour...	[more]
si:ch211-113e8.3	2.860e-47	35.46	dual specificity testis-specific protein kinase 2 ...	[more]
si:dkeyp-75h12.2	3.082e-47	35.36	testis associated actin remodelling kinase 1 [Sour...	[more]
tesk2	2.414e-39	33.96	dual specificity testis-specific protein kinase 2 ...	[more]
limk1a	4.547e-37	29.66	LIM domain kinase 1-like [Source:NCBI gene;Acc:101...	[more]

BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000023685.1	0.000e+0	99.75	SMESG000023685.1	[more]
SMESG000023685.1	0.000e+0	99.74	SMESG000023685.1	[more]
SMESG000004938.1	5.201e-22	29.22	SMESG000004938.1	[more]
SMESG000004938.1	5.366e-22	29.22	SMESG000004938.1	[more]
SMESG000004938.1	5.375e-22	29.22	SMESG000004938.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30007007 ID=SMED30007007|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1679bp
TTTATTGTATAACTTAAATGATTGTCGAAAATTATATTTTTAAACTACTA
TCGATGTTAAAATTATTTATTCATTTTTACAACATACTACACAATATATG
AAGTATCATAATGGTACGAAAATGCCATTGAATTGTTTCAAAAATCATAG
TCTTTCAATTGATAACAAGACAATGTCAAACACAAATCCTAATTCAGAAA
TAATTCCTAAGAGAAATCCAGTTGCTATAGGATTTGCTAATGACATAAAC
TTGTGTTATAGCGATAAAGACTTTAAATCGAATCTTGACATAATTGGATC
AGGATTTTTCGCTAAAGTGTATATAGTGTATCATGTTGTATTGAATTTGA
AAATGGCTTTCAAAGTTCCTAAACCTACTCAGTCAATTAATAAATTTGTC
AAAGAGATTAAACTATTAAAAAGTCTGAATCATGACAACATATTAAAATT
TTATGGAGCTTGTCTTTACAACGGAGTCTTTGGTTACTTAACTGAGTTTC
TCGATTATGGTAATATGTCTCGTCTAATTGAAAAGGAAGGCCCCTTGTTA
GATTGGTCAAACAGAGTTCATATTGCCGAAGACATAGCAAAAGGACTGGT
TTATTTGCACGATCAATTCGTTATACATCGCGATTTATCTGCTGAAAATA
TTCTATTACACAAAACCCAATCCGAAACAAATAATGAGTCGGTGATGTAC
AGTTATCGGGCAGTTATAGCTGATTTCGGTCTTTGCTTGAACATGAAAGA
CGTAAGAGCAGATCGAATGTCTACCGTTGGCAATCCGTTCTACACAGCTC
CTGAGAATCTAAAGAATGAATCACCGTATGATTACAGTTCTGACGTATTC
AGTTTCGGCATGCTGCTTTGTGAACTGATAACCGGCCTAAAAAATGATCC
AAATTTCATACCAAGGACAAATAAATACGGGCTTGATTACAAGAAATTGC
CCATCAAGCGTGACTGTCCGAAATGGATACACCAATTAGCCTTGGACTGC
TGCGTGATCAGCATTTCACGGAGACCTACCATGAAAAGTGCCTATCAGAA
AATTGTAGAAAATGAAATATATATCGATTTGTGGCGCAATACGAGGGAAC
CAAAAAAAAAGATTAATTTGAATCACTCATACAATGTAAATAACCAATTT
CGTGGAGCTTCCATGTCCATTTCCCAAGATTATTATTCCAGTTCCTTATT
GCGCAAATTGTGCAAAAATAATTCCAAAGATGACAATGTGTCGTCACCAT
TGTCACCGATATTAAATGATTGTCAAAAGATTTATCGTCACAACTCAGTT
GATTCATTTATTGAACCGCGAATTTTAAATTTCGTTAAAGCATTTAAGGA
TCCCGGTTATGTCGATGAACCTCTAACCGAATCCATGAAAAGTCTTGATC
CGAGGAAACCTCGGAAATTGTCTCGATGCACCAGCGAATCTAGAGTGCAG
TCTGTTGTCAGGCCACGAGATTCGGCGGCATCAGTGGCAGTGAAGAAATT
CGTATTGTATCAGAAATAGCCTAATTTACACTTGATGAAGTTTGAATGGA
TTTTCCAATGTGTTTGACAGATTTCTAATCATGATTATTTGTAATCATTC
AAATTCCGTTTCACTTTTCTAAAACTGCCGCTCTTGATCGATTATATTTT
TTATTGAAAACCTCATTCAATTAGACAGT

protein sequence of SMED30007007-orf-1

>SMED30007007-orf-1 ID=SMED30007007-orf-1|Name=SMED30007007-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=474bp
MKYHNGTKMPLNCFKNHSLSIDNKTMSNTNPNSEIIPKRNPVAIGFANDI
NLCYSDKDFKSNLDIIGSGFFAKVYIVYHVVLNLKMAFKVPKPTQSINKF
VKEIKLLKSLNHDNILKFYGACLYNGVFGYLTEFLDYGNMSRLIEKEGPL
LDWSNRVHIAEDIAKGLVYLHDQFVIHRDLSAENILLHKTQSETNNESVM
YSYRAVIADFGLCLNMKDVRADRMSTVGNPFYTAPENLKNESPYDYSSDV
FSFGMLLCELITGLKNDPNFIPRTNKYGLDYKKLPIKRDCPKWIHQLALD
CCVISISRRPTMKSAYQKIVENEIYIDLWRNTREPKKKINLNHSYNVNNQ
FRGASMSISQDYYSSSLLRKLCKNNSKDDNVSSPLSPILNDCQKIYRHNS
VDSFIEPRILNFVKAFKDPGYVDEPLTESMKSLDPRKPRKLSRCTSESRV
QSVVRPRDSAASVAVKKFVLYQK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte

Vocabulary: **INTERPRO**
Term	Definition
IPR001245	Ser-Thr/Tyr_kinase_cat_dom
IPR017441	Protein_kinase_ATP_BS
IPR008266	Tyr_kinase_AS
IPR000719	Prot_kinase_dom
IPR011009	Kinase-like_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0004672	protein kinase activity
GO:0005524	ATP binding
GO:0000166	nucleotide binding
GO:0004674	protein serine/threonine kinase activity
GO:0004712	protein serine/threonine/tyrosine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0004871	signal transducer activity
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0006468	protein phosphorylation
GO:0007283	spermatogenesis
GO:0016310	phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0030036	actin cytoskeleton organization
GO:0035556	intracellular signal transduction
GO:0048041	focal adhesion assembly

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0016604	nuclear body

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	G3DSA:1.10.510.10		coord: 48..352 e-value: 1.4E-56 score: 193.7
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 430..444
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 430..449
None	No IPR available	PANTHER	PTHR46485	FAMILY NOT NAMED	coord: 43..397
None	No IPR available	PANTHER	PTHR46485:SF5	CENTER DIVIDER, ISOFORM A	coord: 43..397
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PFAM	PF07714	Pkinase_Tyr	coord: 65..317 e-value: 4.8E-42 score: 144.0
IPR017441	Protein kinase, ATP binding site	PROSITE	PS00107	PROTEIN_KINASE_ATP	coord: 66..89
IPR008266	Tyrosine-protein kinase, active site	PROSITE	PS00109	PROTEIN_KINASE_TYR	coord: 175..187
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 60..326 score: 33.842
IPR011009	Protein kinase-like domain superfamily	SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	coord: 62..360