H/ACA ribonucleoprotein complex subunit

Overview
NameH/ACA ribonucleoprotein complex subunit
Smed IDSMED30006959
Length (bp)721
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of H/ACA ribonucleoprotein complex subunit (SMED30006959) t-SNE clustered cells

Violin plots show distribution of expression levels for H/ACA ribonucleoprotein complex subunit (SMED30006959) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of H/ACA ribonucleoprotein complex subunit (SMED30006959) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for H/ACA ribonucleoprotein complex subunit (SMED30006959) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006959

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 20

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30006959h1SMcG0006393 SmedASXL_004313SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30006959h1SMcG0005166 Contig40297newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006959h1SMcG0005166 Contig40297uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006959h1SMcG0006897 Contig4364GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30006959h1SMcG0006393 dd_Smed_v4_15919_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30006959h1SMcG0006393 dd_Smed_v4_15919_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30006959h1SMcG0006393 dd_Smed_v4_15919_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006959h1SMcG0006393 Contig40297newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006959h1SMcG0006393 Contig40297uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30006959h1SMcG0006393 dd_Smed_v4_3239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30006959h1SMcG0006393 dd_Smed_v4_3239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30006959h1SMcG0006393 dd_Smed_v4_3239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30006959h1SMcG0006393 dd_Smed_v4_3239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30006959h1SMcG0006393 dd_Smed_v4_3239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30006959h1SMcG0006393 dd_Smed_v4_3239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30006959h1SMcG0006393 dd_Smed_v4_7343_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30006959h1SMcG0006393 dd_Smed_v4_7343_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30006959h1SMcG0006393 dd_Smed_v4_7343_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30006959h1SMcG0006393 dd_Smed_v4_7343_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006959h1SMcG0006393 Contig4364GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Human
Match: GAR1 (GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14264])

HSP 1 Score: 112.464 bits (280), Expect = 5.396e-30
Identity = 54/102 (52.94%), Postives = 74/102 (72.55%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            K +D+GPP+ V  +G + H  ED ++CK T +  ++PYFNAPVYLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ PYK+L   R +P P
Sbjct:   60 KGQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP 161
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Human
Match: GAR1 (GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14264])

HSP 1 Score: 112.464 bits (280), Expect = 5.396e-30
Identity = 54/102 (52.94%), Postives = 74/102 (72.55%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            K +D+GPP+ V  +G + H  ED ++CK T +  ++PYFNAPVYLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ PYK+L   R +P P
Sbjct:   60 KGQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP 161
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Celegans
Match: Y66H1A.4 (Probable H/ACA ribonucleoprotein complex subunit 1-like protein [Source:UniProtKB/Swiss-Prot;Acc:Q9TYK1])

HSP 1 Score: 96.2857 bits (238), Expect = 6.031e-24
Identity = 43/95 (45.26%), Postives = 63/95 (66.32%), Query Frame = 3 
Query:  138 DEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVP 422
            D+GPP+ V  +G +SH  +D ++C  T  +IPYFNAP+Y +NKE VGK+DE+FG   +  F + L    KA+SF+  S+ Y+ P K+L  DR +P
Sbjct:   53 DQGPPEEVVLVGVFSHQCQDDIVCNNTSGKIPYFNAPIYFKNKEQVGKIDEIFGSPGENGFSVTLSQGVKASSFEPESQLYIDPGKLLPVDRFLP 147
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Celegans
Match: Y66H1A.4 (Probable H/ACA ribonucleoprotein complex subunit 1-like protein [Source:UniProtKB/Swiss-Prot;Acc:Q9TYK1])

HSP 1 Score: 96.2857 bits (238), Expect = 6.031e-24
Identity = 43/95 (45.26%), Postives = 63/95 (66.32%), Query Frame = 3 
Query:  138 DEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVP 422
            D+GPP+ V  +G +SH  +D ++C  T  +IPYFNAP+Y +NKE VGK+DE+FG   +  F + L    KA+SF+  S+ Y+ P K+L  DR +P
Sbjct:   53 DQGPPEEVVLVGVFSHQCQDDIVCNNTSGKIPYFNAPIYFKNKEQVGKIDEIFGSPGENGFSVTLSQGVKASSFEPESQLYIDPGKLLPVDRFLP 147
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Fly
Match: CG4038 (gene:FBgn0011824 transcript:FBtr0071639)

HSP 1 Score: 98.9821 bits (245), Expect = 6.841e-25
Identity = 45/100 (45.00%), Postives = 65/100 (65.00%), Query Frame = 3 
Query:  138 DEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRTP 437
            D GPP+ V  +G+Y +  ++ L+CK+  + +PYFNAP++LENKE VGK+DE+FG + D    +KL D   A SFK N K ++ P K+L   R +P P  P
Sbjct:   62 DTGPPERVIPLGNYVYSCQNDLVCKVDIQDVPYFNAPIFLENKEQVGKIDEIFGTVRDYSVSIKLSDNVYANSFKPNQKLFIDPGKLLPIARFLPKPPQP 161
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Zebrafish
Match: gar1 (GAR1 homolog, ribonucleoprotein [Source:NCBI gene;Acc:393950])

HSP 1 Score: 110.153 bits (274), Expect = 3.763e-29
Identity = 53/100 (53.00%), Postives = 70/100 (70.00%), Query Frame = 3 
Query:  135 EDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            +D GPP+ V  +G + H  ED ++CK   E  ++PYFNAPVYLENKE +GKVDE+FGQL D +F +KL D  KA+SFK+  KFY+ P K+L   R +P P
Sbjct:   56 QDYGPPEYVVALGEFMHPCEDEIVCKCVTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSDNMKASSFKKLQKFYIDPMKLLPLQRFLPRP 155
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Zebrafish
Match: gar1 (GAR1 homolog, ribonucleoprotein [Source:NCBI gene;Acc:393950])

HSP 1 Score: 110.153 bits (274), Expect = 4.222e-29
Identity = 53/100 (53.00%), Postives = 70/100 (70.00%), Query Frame = 3 
Query:  135 EDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            +D GPP+ V  +G + H  ED ++CK   E  ++PYFNAPVYLENKE +GKVDE+FGQL D +F +KL D  KA+SFK+  KFY+ P K+L   R +P P
Sbjct:   56 QDYGPPEYVVALGEFMHPCEDEIVCKCVTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSDNMKASSFKKLQKFYIDPMKLLPLQRFLPRP 155
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Xenopus
Match: gar1 (GAR1 homolog, ribonucleoprotein [Source:NCBI gene;Acc:496698])

HSP 1 Score: 113.62 bits (283), Expect = 2.217e-30
Identity = 55/99 (55.56%), Postives = 73/99 (73.74%), Query Frame = 3 
Query:  138 DEGPPDVVEEIGHYSHVYEDGLICK-ITHE-RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            D+GPP+ V E+G + H  ED ++CK IT E R+PYFNAP+YLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ P K+L   R +P P
Sbjct:   57 DQGPPESVVEVGEFMHPCEDDVVCKCITQENRVPYFNAPIYLENKEQIGKVDEIFGQLRDFYFSIKLSENMKASSFKKLQKFYIDPAKLLPLQRFLPRP 155
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Xenopus
Match: gar1 (GAR1 homolog, ribonucleoprotein [Source:NCBI gene;Acc:496698])

HSP 1 Score: 114.005 bits (284), Expect = 6.274e-30
Identity = 55/99 (55.56%), Postives = 73/99 (73.74%), Query Frame = 3 
Query:  138 DEGPPDVVEEIGHYSHVYEDGLICK-ITHE-RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            D+GPP+ V E+G + H  ED ++CK IT E R+PYFNAP+YLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ P K+L   R +P P
Sbjct:   57 DQGPPESVVEVGEFMHPCEDDVVCKCITQENRVPYFNAPIYLENKEQIGKVDEIFGQLRDFYFSIKLSENMKASSFKKLQKFYIDPAKLLPLQRFLPRP 155
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Mouse
Match: Gar1 (GAR1 ribonucleoprotein [Source:MGI Symbol;Acc:MGI:1930948])

HSP 1 Score: 115.931 bits (289), Expect = 1.230e-31
Identity = 56/102 (54.90%), Postives = 74/102 (72.55%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            K +D+GPP+ V  +G + H  ED ++CK T E  ++PYFNAPVYLENKE VGKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ PYK+L   R +P P
Sbjct:   71 KFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQVGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP 172
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Mouse
Match: Gar1 (GAR1 ribonucleoprotein [Source:MGI Symbol;Acc:MGI:1930948])

HSP 1 Score: 115.161 bits (287), Expect = 5.024e-31
Identity = 56/102 (54.90%), Postives = 74/102 (72.55%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            K +D+GPP+ V  +G + H  ED ++CK T E  ++PYFNAPVYLENKE VGKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ PYK+L   R +P P
Sbjct:   71 KFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQVGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP 172
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Mouse
Match: Gar1 (GAR1 ribonucleoprotein [Source:MGI Symbol;Acc:MGI:1930948])

HSP 1 Score: 54.299 bits (129), Expect = 1.347e-9
Identity = 25/48 (52.08%), Postives = 34/48 (70.83%), Query Frame = 3 
Query:  285 DEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            DE+FGQL D +F +KL +  KA+SFK+  KFY+ PYK+L   R +P P
Sbjct:    1 DEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP 48
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. UniProt/SwissProt
Match: sp|Q9CY66|GAR1_MOUSE (H/ACA ribonucleoprotein complex subunit 1 OS=Mus musculus OX=10090 GN=Gar1 PE=1 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 3.514e-30
Identity = 56/102 (54.90%), Postives = 74/102 (72.55%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            K +D+GPP+ V  +G + H  ED ++CK T E  ++PYFNAPVYLENKE VGKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ PYK+L   R +P P
Sbjct:   71 KFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQVGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP 172
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. UniProt/SwissProt
Match: sp|Q6AYA1|GAR1_RAT (H/ACA ribonucleoprotein complex subunit 1 OS=Rattus norvegicus OX=10116 GN=Gar1 PE=2 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 4.564e-30
Identity = 55/102 (53.92%), Postives = 74/102 (72.55%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            K +D+GPP+ V  +G + H  ED ++CK T E  ++PYFNAPVYLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ PYK+L   R +P P
Sbjct:   62 KFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP 163
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. UniProt/SwissProt
Match: sp|Q5RJV1|GAR1_XENTR (H/ACA ribonucleoprotein complex subunit 1 OS=Xenopus tropicalis OX=8364 GN=gar1 PE=2 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.146e-29
Identity = 55/99 (55.56%), Postives = 73/99 (73.74%), Query Frame = 3 
Query:  138 DEGPPDVVEEIGHYSHVYEDGLICK-ITHE-RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            D+GPP+ V E+G + H  ED ++CK IT E R+PYFNAP+YLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ P K+L   R +P P
Sbjct:   56 DQGPPESVVEVGEFMHPCEDDVVCKCITQENRVPYFNAPIYLENKEQIGKVDEIFGQLRDFYFSIKLSENMKASSFKKLQKFYIDPAKLLPLQRFLPRP 154
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. UniProt/SwissProt
Match: sp|Q9NY12|GAR1_HUMAN (H/ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 2.591e-29
Identity = 54/102 (52.94%), Postives = 74/102 (72.55%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            K +D+GPP+ V  +G + H  ED ++CK T +  ++PYFNAPVYLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ PYK+L   R +P P
Sbjct:   60 KGQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP 161
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. UniProt/SwissProt
Match: sp|Q7ZVE0|GAR1_DANRE (H/ACA ribonucleoprotein complex subunit 1 OS=Danio rerio OX=7955 GN=gar1 PE=2 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 3.264e-28
Identity = 53/100 (53.00%), Postives = 70/100 (70.00%), Query Frame = 3 
Query:  135 EDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            +D GPP+ V  +G + H  ED ++CK   E  ++PYFNAPVYLENKE +GKVDE+FGQL D +F +KL D  KA+SFK+  KFY+ P K+L   R +P P
Sbjct:   56 QDYGPPEYVVALGEFMHPCEDEIVCKCVTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSDNMKASSFKKLQKFYIDPMKLLPLQRFLPRP 155
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. TrEMBL
Match: A0A401Q1H1 (H/ACA ribonucleoprotein complex subunit (Fragment) OS=Scyliorhinus torazame OX=75743 GN=scyTo_0016924 PE=3 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 3.426e-29
Identity = 57/99 (57.58%), Postives = 73/99 (73.74%), Query Frame = 3 
Query:  138 DEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            D+GPPD V E+GH+ H  ED ++CK T E  R+PYFNAPVYLENKE +GKVDE+FGQL + +F +KL D  KATSFK+  KF++ P K+L   R +P P
Sbjct:   96 DQGPPDYVVELGHFMHPCEDEIVCKCTSEENRVPYFNAPVYLENKEQIGKVDEIFGQLRNFYFSVKLSDNMKATSFKKLQKFFVDPAKLLPLQRFLPRP 194
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. TrEMBL
Match: A0A1W2Q680 (H/ACA ribonucleoprotein complex subunit (Fragment) OS=Rattus norvegicus OX=10116 GN=Gar1 PE=1 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 2.223e-28
Identity = 55/102 (53.92%), Postives = 74/102 (72.55%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            K +D+GPP+ V  +G + H  ED ++CK T E  ++PYFNAPVYLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ PYK+L   R +P P
Sbjct:   62 KFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP 163
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. TrEMBL
Match: D3YZ09 (H/ACA ribonucleoprotein complex subunit (Fragment) OS=Mus musculus OX=10090 GN=Gar1 PE=1 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 2.549e-28
Identity = 56/102 (54.90%), Postives = 74/102 (72.55%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            K +D+GPP+ V  +G + H  ED ++CK T E  ++PYFNAPVYLENKE VGKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ PYK+L   R +P P
Sbjct:   71 KFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQVGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP 172
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. TrEMBL
Match: A0A1S3JWU0 (H/ACA ribonucleoprotein complex subunit OS=Lingula unguis OX=7574 GN=LOC106176877 PE=3 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 3.409e-28
Identity = 53/99 (53.54%), Postives = 71/99 (71.72%), Query Frame = 3 
Query:  135 EDEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPR 431
            +D GPP+ V E+G Y    ED ++CK T+E+IPYFNAPVYLENK+ +GKVDE+FG + D  F +KL D  KA SF  + KFY+ PYK+L  +R +P P+
Sbjct:   32 QDYGPPEHVVELGQYMQPCEDDIVCKCTNEKIPYFNAPVYLENKQQIGKVDEIFGPIRDFFFSVKLSDDMKAKSFNTDQKFYIDPYKLLPLERFLPQPK 130
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. TrEMBL
Match: A0A4W3HDY4 (H/ACA ribonucleoprotein complex subunit OS=Callorhinchus milii OX=7868 GN=gar1 PE=3 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 4.151e-28
Identity = 55/99 (55.56%), Postives = 71/99 (71.72%), Query Frame = 3 
Query:  138 DEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            D GPPD V E+GH+ H  ED ++CK T E  +IPYFNAP+YLENKE +GKVDE+FGQ+ D +F +KL +  KA SFK+  KFY+ P K+L   R +P P
Sbjct:   47 DMGPPDSVVELGHFMHPCEDDIVCKCTSEENKIPYFNAPIYLENKEQIGKVDEIFGQIRDFYFSVKLSENMKAASFKKLQKFYVDPAKLLPLQRFLPRP 145
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Cavefish
Match: gar1 (GAR1 ribonucleoprotein [Source:NCBI gene;Acc:103043093])

HSP 1 Score: 108.227 bits (269), Expect = 2.192e-28
Identity = 52/102 (50.98%), Postives = 71/102 (69.61%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            + +D GPPD V  +G + H  ED ++CK   E  ++P+FNAPVYLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ P K+L   R +P P
Sbjct:   62 RYQDFGPPDHVVALGEFMHPCEDDIVCKCVAEDNKVPFFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYVDPMKLLPLQRFLPRP 163
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Cavefish
Match: gar1 (GAR1 ribonucleoprotein [Source:NCBI gene;Acc:103043093])

HSP 1 Score: 107.842 bits (268), Expect = 2.511e-28
Identity = 52/102 (50.98%), Postives = 71/102 (69.61%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            + +D GPPD V  +G + H  ED ++CK   E  ++P+FNAPVYLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ P K+L   R +P P
Sbjct:   62 RYQDFGPPDHVVALGEFMHPCEDDIVCKCVAEDNKVPFFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYVDPMKLLPLQRFLPRP 163
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Yeast
Match: GAR1 (Protein component of the H/ACA snoRNP pseudouridylase complex; involved in the modification and cleavage of the 18S pre-rRNA [Source:SGD;Acc:S000001131])

HSP 1 Score: 103.219 bits (256), Expect = 9.587e-28
Identity = 47/98 (47.96%), Postives = 66/98 (67.35%), Query Frame = 3 
Query:  141 EGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRT 434
            +GPPD V E+G + H  E  ++C+  + +IPYFNAP+YLENK  VGKVDE+ G L +  F +K  D  +ATSFKE  KFY++  K+L  +R +P P+ 
Sbjct:   31 QGPPDTVLEMGAFLHPCEGDIVCRSINTKIPYFNAPIYLENKTQVGKVDEILGPLNEVFFTIKCGDGVQATSFKEGDKFYIAADKLLPIERFLPKPKV 128
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Nematostella
Match: EDO39549 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Q5])

HSP 1 Score: 113.235 bits (282), Expect = 3.185e-31
Identity = 50/96 (52.08%), Postives = 70/96 (72.92%), Query Frame = 3 
Query:  141 EGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            +GPP+ V E+G ++H  E  L+CK T+E+IPYFNAPVYLENKE +GKVD++FG + D  F +K+ D   A+SFK+  KF++ PYK+L   R +P P
Sbjct:   35 QGPPETVIELGSFNHPCEGDLVCKCTNEKIPYFNAPVYLENKEQIGKVDDIFGPMQDFFFSVKVSDNMNASSFKKGQKFFIDPYKLLPLARFLPKP 130
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Medaka
Match: gar1 (GAR1 ribonucleoprotein [Source:NCBI gene;Acc:101172885])

HSP 1 Score: 109.383 bits (272), Expect = 5.716e-29
Identity = 53/100 (53.00%), Postives = 71/100 (71.00%), Query Frame = 3 
Query:  135 EDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            +D GPP+ V  +G + H  ED ++CK T E  ++PYFNAPVYLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ P K+L   R +P P
Sbjct:   65 QDYGPPEHVVALGEFVHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPMKLLPLQRFLPRP 164
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Medaka
Match: gar1 (GAR1 ribonucleoprotein [Source:NCBI gene;Acc:101172885])

HSP 1 Score: 110.153 bits (274), Expect = 1.162e-28
Identity = 53/100 (53.00%), Postives = 71/100 (71.00%), Query Frame = 3 
Query:  135 EDEGPPDVVEEIGHYSHVYEDGLICKITHE--RIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTP 428
            +D GPP+ V  +G + H  ED ++CK T E  ++PYFNAPVYLENKE +GKVDE+FGQL D +F +KL +  KA+SFK+  KFY+ P K+L   R +P P
Sbjct:   65 QDYGPPEHVVALGEFVHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPMKLLPLQRFLPRP 164
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Planmine SMEST
Match: SMESG000056130.1 (SMESG000056130.1)

HSP 1 Score: 255.758 bits (652), Expect = 1.625e-86
Identity = 167/168 (99.40%), Postives = 168/168 (100.00%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRTPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFQNDRKRSFGGDSSNAKRIKFD 632
            KMEDEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENK+VVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRTPGAGASRGGRGGDRGRGGARGGGRGGDRGGRGGFNRGAPRGRGGFQNDRKRSFGGDSSNAKRIKFD
Sbjct:   37 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKQVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRTPGAGASRGGRGGDRGRGGARGGGRGGDRGGRGGFNRGAPRGRGGFQNDRKRSFGGDSSNAKRIKFD 204
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Planmine SMEST
Match: SMESG000056130.1 (SMESG000056130.1)

HSP 1 Score: 252.292 bits (643), Expect = 1.018e-76
Identity = 167/168 (99.40%), Postives = 168/168 (100.00%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRTPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFQNDRKRSFGGDSSNAKRIKFD 632
            KMEDEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENK+VVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRTPGAGASRGGRGGDRGRGGARGGGRGGDRGGRGGFNRGAPRGRGGFQNDRKRSFGGDSSNAKRIKFD
Sbjct: 2647 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKQVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRTPGAGASRGGRGGDRGRGGARGGGRGGDRGGRGGFNRGAPRGRGGFQNDRKRSFGGDSSNAKRIKFD 2814
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit vs. Planmine SMEST
Match: SMESG000056130.1 (SMESG000056130.1)

HSP 1 Score: 252.292 bits (643), Expect = 1.143e-76
Identity = 167/168 (99.40%), Postives = 168/168 (100.00%), Query Frame = 3 
Query:  129 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKEVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRTPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFQNDRKRSFGGDSSNAKRIKFD 632
            KMEDEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENK+VVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRTPGAGASRGGRGGDRGRGGARGGGRGGDRGGRGGFNRGAPRGRGGFQNDRKRSFGGDSSNAKRIKFD
Sbjct: 2629 KMEDEGPPDVVEEIGHYSHVYEDGLICKITHERIPYFNAPVYLENKQVVGKVDEVFGQLADPHFHLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRTPGAGASRGGRGGDRGRGGARGGGRGGDRGGRGGFNRGAPRGRGGFQNDRKRSFGGDSSNAKRIKFD 2796
The following BLAST results are available for this feature:
BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
GAR15.396e-3052.94GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGN... [more]
GAR15.396e-3052.94GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Y66H1A.46.031e-2445.26Probable H/ACA ribonucleoprotein complex subunit 1... [more]
Y66H1A.46.031e-2445.26Probable H/ACA ribonucleoprotein complex subunit 1... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG40386.841e-2545.00gene:FBgn0011824 transcript:FBtr0071639[more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
gar13.763e-2953.00GAR1 homolog, ribonucleoprotein [Source:NCBI gene;... [more]
gar14.222e-2953.00GAR1 homolog, ribonucleoprotein [Source:NCBI gene;... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
gar12.217e-3055.56GAR1 homolog, ribonucleoprotein [Source:NCBI gene;... [more]
gar16.274e-3055.56GAR1 homolog, ribonucleoprotein [Source:NCBI gene;... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Gar11.230e-3154.90GAR1 ribonucleoprotein [Source:MGI Symbol;Acc:MGI:... [more]
Gar15.024e-3154.90GAR1 ribonucleoprotein [Source:MGI Symbol;Acc:MGI:... [more]
Gar11.347e-952.08GAR1 ribonucleoprotein [Source:MGI Symbol;Acc:MGI:... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9CY66|GAR1_MOUSE3.514e-3054.90H/ACA ribonucleoprotein complex subunit 1 OS=Mus m... [more]
sp|Q6AYA1|GAR1_RAT4.564e-3053.92H/ACA ribonucleoprotein complex subunit 1 OS=Rattu... [more]
sp|Q5RJV1|GAR1_XENTR1.146e-2955.56H/ACA ribonucleoprotein complex subunit 1 OS=Xenop... [more]
sp|Q9NY12|GAR1_HUMAN2.591e-2952.94H/ACA ribonucleoprotein complex subunit 1 OS=Homo ... [more]
sp|Q7ZVE0|GAR1_DANRE3.264e-2853.00H/ACA ribonucleoprotein complex subunit 1 OS=Danio... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A401Q1H13.426e-2957.58H/ACA ribonucleoprotein complex subunit (Fragment)... [more]
A0A1W2Q6802.223e-2853.92H/ACA ribonucleoprotein complex subunit (Fragment)... [more]
D3YZ092.549e-2854.90H/ACA ribonucleoprotein complex subunit (Fragment)... [more]
A0A1S3JWU03.409e-2853.54H/ACA ribonucleoprotein complex subunit OS=Lingula... [more]
A0A4W3HDY44.151e-2855.56H/ACA ribonucleoprotein complex subunit OS=Callorh... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
gar12.192e-2850.98GAR1 ribonucleoprotein [Source:NCBI gene;Acc:10304... [more]
gar12.511e-2850.98GAR1 ribonucleoprotein [Source:NCBI gene;Acc:10304... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
GAR19.587e-2847.96Protein component of the H/ACA snoRNP pseudouridyl... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO395493.185e-3152.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
gar15.716e-2953.00GAR1 ribonucleoprotein [Source:NCBI gene;Acc:10117... [more]
gar11.162e-2853.00GAR1 ribonucleoprotein [Source:NCBI gene;Acc:10117... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000056130.11.625e-8699.40SMESG000056130.1[more]
SMESG000056130.11.018e-7699.40SMESG000056130.1[more]
SMESG000056130.11.143e-7699.40SMESG000056130.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006959 ID=SMED30006959|Name=H/ACA ribonucleoprotein complex subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=721bp
TCTATATAAATCTTATATGAATGGGATTTGATAGAGGTAATAATAGAGGT
GGTAGTTTTAACCGTGGAGGAAATAGAGGTGCTCCACGAGGAGGTGGAAA
TAGAGGTGGTCGTGGTGGCTACGGTCGTAAAATGGAGGATGAAGGGCCTC
CTGATGTTGTTGAAGAAATTGGTCATTATTCTCACGTTTATGAAGACGGA
TTAATTTGTAAAATTACTCATGAAAGAATTCCGTATTTTAATGCTCCTGT
TTACTTGGAAAATAAAGAAGTTGTTGGAAAAGTCGATGAAGTGTTTGGTC
AATTAGCCGATCCACATTTCCACCTAAAGCTTTTAGATACATTTAAAGCC
ACTTCATTCAAAGAAAATTCTAAATTTTACATGTCTCCTTACAAGATGCT
AACAAAGGACAGACTTGTTCCCACGCCTAGAACCCCAGGTGCAGGTGCTT
CAAGAGGTGGTAGAGGGGGTGATAGAGGTCGAGGTGGAGCCCGTGGTGGT
GGAAGAGGAGGTGACCGCGGGGGTAGAGGTGGGTTTAATAGAGGTGCTCC
TAGAGGTCGAGGTGGATTTCAAAATGATAGAAAAAGATCATTTGGTGGAG
ATAGTAGTAATGCCAAACGGATTAAGTTTGACTAAGTACAAAACTGATTT
GTAAATAAATTATAAAAAAATATTGTTAACTTTTTATTTATTCGGGTAGA
TTTTAAATCATATAATGTAAG
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protein sequence of SMED30006959-orf-1

>SMED30006959-orf-1 ID=SMED30006959-orf-1|Name=SMED30006959-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=205bp
MGFDRGNNRGGSFNRGGNRGAPRGGGNRGGRGGYGRKMEDEGPPDVVEEI
GHYSHVYEDGLICKITHERIPYFNAPVYLENKEVVGKVDEVFGQLADPHF
HLKLLDTFKATSFKENSKFYMSPYKMLTKDRLVPTPRTPGAGASRGGRGG
DRGRGGARGGGRGGDRGGRGGFNRGAPRGRGGFQNDRKRSFGGDSSNAKR
IKFD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0007601visual perception
GO:0001522pseudouridine synthesis
GO:0042254ribosome biogenesis
GO:0000454snoRNA guided rRNA pseudouridine synthesis
GO:0006364rRNA processing
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
GO:0031429box H/ACA snoRNP complex
GO:0000784nuclear chromosome, telomeric region
GO:0001650fibrillar center
GO:0001651dense fibrillar component
GO:0005634nucleus
GO:0005730nucleolus
GO:0015030Cajal body
GO:0030529intracellular ribonucleoprotein complex
GO:0090661box H/ACA telomerase RNP complex
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR038664Gar1/Naf1_Cbf5-bd_sf
IPR007504H/ACA_rnp_Gar1/Naf1
IPR021154H/ACA_rnp_Gar1
IPR009000Transl_B-barrel_sf
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
GO:0005515protein binding
GO:0030515snoRNA binding
GO:0034513box H/ACA snoRNA binding
GO:0070034telomerase RNA binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR038664H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domainGENE3DG3DSA:2.40.10.230coord: 43..134
e-value: 4.8E-31
score: 108.4
IPR007504H/ACA ribonucleoprotein complex, subunit Gar1/Naf1PFAMPF04410Gar1coord: 33..131
e-value: 5.0E-29
score: 101.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 181..204
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..41
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 130..204
NoneNo IPR availablePANTHERPTHR23237:SF10H/ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1coord: 10..184
NoneNo IPR availablePANTHERPTHR23237NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1coord: 10..184
NoneNo IPR availablePRODOMPD020235coord: 50..136
e-value: 4.0E-22
score: 257.0
IPR009000Translation protein, beta-barrel domain superfamilySUPERFAMILYSSF50447Translation proteinscoord: 47..121