Anoctamin

Overview
NameAnoctamin
Smed IDSMED30006906
Length (bp)2834
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Anoctamin (SMED30006906) t-SNE clustered cells

Violin plots show distribution of expression levels for Anoctamin (SMED30006906) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Anoctamin (SMED30006906) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Anoctamin (SMED30006906) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006906

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30006906h1SMcG0017356 dd_Smed_v4_5046_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30006906h1SMcG0017356 dd_Smed_v4_5046_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30006906h1SMcG0017356 dd_Smed_v4_5046_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006906h1SMcG0017356 Contig50307newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006906h1SMcG0017356 Contig50307uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30006906h1SMcG0017356 dd_Smed_v4_5046_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Anoctamin vs. Ensembl Human
Match: ANO7 (anoctamin 7 [Source:HGNC Symbol;Acc:HGNC:31677])

HSP 1 Score: 728.013 bits (1878), Expect = 0.000e+0
Identity = 381/806 (47.27%), Postives = 551/806 (68.36%), Query Frame = 2 
Query:  347 RRIDYVIVWEQD----RIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLF--DNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNN---SLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL--------LNMTKNE 2713
            R  D+V+VWE+D    R   +   +R      +R+ F + L   GL  +++  +     +++  +   + ++C YAE L  ++PLQ  P    ++S  +L +  IPN +   +P  P  + +  F+ ++L ++LG  N+DTFF++T+RHQ+  EILA T YG + K  +GI +++ E + SAA+PLH+GP + P +      L N+RQ+LF++WA+W K+ KYQP++++R Y+GEK+A+YFAWLG YT WL PA++VG  VF+ G   + S   ++E+C + ++F+MCPLC     C +W LS  C  +Q   LFDH GTVFFS+FM++WAV  LE WKRK+A L+YRWD  DYE+ +E+PRP++ A A     NP+TG +EPYFP   R +RML G + IVVM  +V++ ++ +I+YR ++AI +    N LL + A   AS++ ++VNL+ I+ L  +Y  LA+ LT+WEMHRT+T+FED  T+KV++F+FVNFYSS  YIAFFKGRF GYPG Y   FG+RNE+C+ G CL ELAQ++ +IMVG Q+INN+QE+ +PKL  W+ +F+         +        W +DY+L+P EGLFDEYLEM++QFGF+TIFVAA PLAP FAL+NNW+EIRLDA K V   RRPVAERAQD+G WF IL  +  L++ISNAFL+AF+SDF+P+  Y+++    L G++NFTLA AP++   + +  CRYR FRD +G  ++ YW LLAIRL FVIVFEH+VF V  L+D+L+PD+PES++I+++R+ Y+AKQAL         N TK+E
Sbjct:  108 RIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQAPRL-NQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC---LDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEVLFGTNGTKDE 909
[Close]
BLAST of Anoctamin vs. Ensembl Human
Match: ANO7 (anoctamin 7 [Source:HGNC Symbol;Acc:HGNC:31677])

HSP 1 Score: 682.174 bits (1759), Expect = 0.000e+0
Identity = 358/754 (47.48%), Postives = 515/754 (68.30%), Query Frame = 2 
Query:  350 RIDYVIVWEQD----RIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLF--DNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNN---SLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFE 2584
            RID+V+VWE+D    R   +   +R      +R+ F + L   GL  +++  +     +++  +   + ++C YAE L  ++PLQ  P    ++S  +L +  IPN +   +P  P  + +  F+ ++L ++LG  N+DTFF++T+RHQ+  EILA T YG + K  +GI +++ E + SAA+PLH+GP + P +      L N+RQ+LF++WA+W K+ KYQP++++R Y+GEK+A+YFAWLG YT WL PA++VG  VF+ G   + S   ++E+C + ++F+MCPLC     C +W LS  C  +Q   LFDH GTVFFS+FM++WAV  LE WKRK+A L+YRWD  DYE+ +E+PRP++ A A     NP+TG +EPYFP   R +RML G + IVVM  +V++ ++ +I+YR ++AI +    N LL + A   AS++ ++VNL+ I+ L  +Y  LA+ LT+WEMHRT+T+FED  T+KV++F+FVNFYSS  YIAFFKGRF GYPG Y   FG+RNE+C+ G CL ELAQ++ +IMVG Q+INN+QE+ +PKL  W+ +F+         +        W +DY+L+P EGLFDEYLEM++QFGF+TIFVAA PLAP FAL+NNW+EIRLDA K V   RRPVAERAQD+G WF IL  +  L++ISNAFL+AF+SDF+P+  Y+++    L G++NFTLA AP++   + +  CRYR FRD +G  ++ YW LLAIRL FVIVFE
Sbjct:  108 RIDFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQAPRL-NQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC---LDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYSQTYWNLLAIRLAFVIVFE 857
[Close]
BLAST of Anoctamin vs. Ensembl Human
Match: ANO4 (anoctamin 4 [Source:HGNC Symbol;Acc:HGNC:23837])

HSP 1 Score: 509.605 bits (1311), Expect = 1.244e-165
Identity = 338/873 (38.72%), Postives = 492/873 (56.36%), Query Frame = 2 
Query:  245 NLKKDKNKESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPH---FSERVLKFFLIPNFMKNELPYSP--------------DCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKY-SLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSG--KDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----------FLLDGYVNFTLA---WAPNNSLSEP--------------CRYRDFRDVNGKLTRF-----YWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            NL    +  SR E        +      Y  DG  RIDY++V+ +       +P+  +R       F   +   GL  E+E       +I F+K+H P+ ++  YAE +N R+P +    + P    F  R+ K   I  F +  LP  P              DC+ TA F   ++  ++ + N++TFF+   R ++   IL    Y  + K +IG++R++    Y AA+PLHEG       +       N R +L+E WA W  +YKYQP++ +R Y+GEKI +YFAWLG YT  LFPA+ +G+FVF+YG+ T+    +SKE+C   +   MCP+C  +K C +  LSD C Y+++T+LFD+  TVFF++FM+VWA  FLE WKR+ A ++Y WD +D+EEE+E+ RP++ A  ++K R+NP++G  EPY     +  R++     I  ++  +I  +F I +     +     F   L+R+ + +  + +A  +N  +IM L ++YEK+A  LT  E  RTE+E+E+  T+K++LF+FVN  SS FYIAFF GRF G+PG Y  L    R E+C    CL +L  QM IIMV  Q  NN  E+  P +  W+ R K     + Q  G  + +    W +DY L P    GLFDEYLEMI+QFGF TIFVAAFPLAP  AL+NN +EIRLDA K V   RRP+A RA+D+G W+ IL  I  LS+I+NAF+IA TSDFIP+ VY Y +             + GYVN +L+    +   + SEP              CRYRD+RD    L  +     +W +LA RL F+IVFEH+VF + +LI  LIPD+P+ L+  MRR+ Y+ ++ +
Sbjct:   48 NLTSTSDDASRLEAGGETVPERNKSNGLYFRDGKCRIDYILVYRKS------NPQTEKREV-----FERNIRAEGLQMEKESSLINSDII-FVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDK--QISRF-RRWLPKKPMRLDKETLPDLEENDCY-TAPFSQQRIHHFIIH-NKETFFNNATRSRIVHHILQRIKY-EEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTH-GAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDII-MCPVC--DKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRK-----VRQEHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 893
[Close]
BLAST of Anoctamin vs. Ensembl Human
Match: ANO3 (anoctamin 3 [Source:HGNC Symbol;Acc:HGNC:14004])

HSP 1 Score: 506.523 bits (1303), Expect = 1.578e-165
Identity = 343/841 (40.78%), Postives = 488/841 (58.03%), Query Frame = 2 
Query:  338 DGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLK----FFLIPNFM--------KNELP--YSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGP--AEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKR-VNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPL--FDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYS-LFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWF--HRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPY--EGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----------FLLDGYVNFTLAWAPNNSL----SEPCRYRDFRDVNG-----KLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMTKNEMGSLKR 2731
            DG +RIDY++V+ +  I  +            R  F + L   GL  E+E   +   ++ FIKIHIP++ +C YAE LN R+P +    +T   S+ + +    F  I N+M        K+  P     DC+ T  F   ++  ++   N+DTFFS   R ++   +L  T Y      ++GI ++I+   Y AA+P HEG   +  P    G     N R +L+E WA+W  +YK+QP++ IR Y+GEKI +YFAWLG YT  L PA++VG+ VF YG+ TM +  +S+EIC     F MCPLC  +K C    L+D C Y+++TYLFD+ GTVFF+IFM++WA  FLE WKR+ + L+Y WD +++EEE+E  RP++ A   +   VNP+TG  EP+ P + ++ R+L  V  I  M  +VI  + GV++YR+++      F    ++       S +A  +N I+IM L L YEK+AY LT  E  RTE+E+E+   +K++LF+FVN  SSIFYIAFF GRF G+PGKY+ LF   R E+C    CL +L  QM +IM   QI NN  E+  P +  W+  H+ K+G++        D     W  D+ L P    GL DEYLEM++QFGF TIFVAAFPLAP  AL+NN +EIRLDA K V   RRP+  RA D+G W  IL  I  L++I+NAF+IA TSD+IP+ VY+Y +             L GYVN +L++   + L    S  CRYRD+R         + T  YW +LA RL F+IVFEH+VFG+   I  LIPDVP+ L   +RR+ Y+ ++ +       +   +R
Sbjct:   13 DGKKRIDYILVYRKTNIQYD-----------KRNTFEKNLRAEGLMLEKEPAIASPDIM-FIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCY-TGPFSRARIHHFI-INNKDTFFSNATRSRIVYHMLERTKY-ENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQ---NNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVF-MCPLC--DKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIH--------DASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQQQRR 824
[Close]
BLAST of Anoctamin vs. Ensembl Human
Match: ANO4 (anoctamin 4 [Source:HGNC Symbol;Acc:HGNC:23837])

HSP 1 Score: 509.22 bits (1310), Expect = 4.906e-165
Identity = 338/873 (38.72%), Postives = 492/873 (56.36%), Query Frame = 2 
Query:  245 NLKKDKNKESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPH---FSERVLKFFLIPNFMKNELPYSP--------------DCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKY-SLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSG--KDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----------FLLDGYVNFTLA---WAPNNSLSEP--------------CRYRDFRDVNGKLTRF-----YWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            NL    +  SR E        +      Y  DG  RIDY++V+ +       +P+  +R       F   +   GL  E+E       +I F+K+H P+ ++  YAE +N R+P +    + P    F  R+ K   I  F +  LP  P              DC+ TA F   ++  ++ + N++TFF+   R ++   IL    Y  + K +IG++R++    Y AA+PLHEG       +       N R +L+E WA W  +YKYQP++ +R Y+GEKI +YFAWLG YT  LFPA+ +G+FVF+YG+ T+    +SKE+C   +   MCP+C  +K C +  LSD C Y+++T+LFD+  TVFF++FM+VWA  FLE WKR+ A ++Y WD +D+EEE+E+ RP++ A  ++K R+NP++G  EPY     +  R++     I  ++  +I  +F I +     +     F   L+R+ + +  + +A  +N  +IM L ++YEK+A  LT  E  RTE+E+E+  T+K++LF+FVN  SS FYIAFF GRF G+PG Y  L    R E+C    CL +L  QM IIMV  Q  NN  E+  P +  W+ R K     + Q  G  + +    W +DY L P    GLFDEYLEMI+QFGF TIFVAAFPLAP  AL+NN +EIRLDA K V   RRP+A RA+D+G W+ IL  I  LS+I+NAF+IA TSDFIP+ VY Y +             + GYVN +L+    +   + SEP              CRYRD+RD    L  +     +W +LA RL F+IVFEH+VF + +LI  LIPD+P+ L+  MRR+ Y+ ++ +
Sbjct:   83 NLTSTSDDASRLEAGGETVPERNKSNGLYFRDGKCRIDYILVYRKS------NPQTEKREV-----FERNIRAEGLQMEKESSLINSDII-FVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDK--QISRF-RRWLPKKPMRLDKETLPDLEENDCY-TAPFSQQRIHHFIIH-NKETFFNNATRSRIVHHILQRIKY-EEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTH-GAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDII-MCPVC--DKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRK-----VRQEHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 928
[Close]
BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-1 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286])

HSP 1 Score: 232.261 bits (591), Expect = 5.851e-64
Identity = 196/717 (27.34%), Postives = 331/717 (46.16%), Query Frame = 2 
Query:  692 FATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGE-------------------------IGIDRMIDEEIYSAAYPLHEGPAEVP-------------TDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNY-----EKGCRYWNLSDICFYSQMTYL----FDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNE---DCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWF--HRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQ 2686
            F  A F+      +L Y +E +FF+++QR  +  +IL      +  KGE                          G+  ++  ++Y  A+ LH    E P              + + +++L  RR +       W ++YK+QP+  IR+Y+GE+IA YFAW G +   L+PA + G+ VF+YG +     +IS    D N+    C + N+        C   N   + F+S +T      FD     FF++FMS+W   F++ WKR N+ LSY+W++ D+    E  RPE+    ++ + +P+TG +    P   R  +ML   + +    ++V+I ++ V + +I +               + A+   +I+N +  M LG +Y  L  +L  WE HRTE+E  + L VK++ F+ VN Y+S+FY+AF +   +G   + +  FGL  E    C + +C   LA Q+    +        +++ LP  V  F    +       V++   D    L  E  K    + +  E  E I+ FG   +F + FPLAP  ALI  ++++R+DA +L+   R+P+      +G W  IL  +   ++ +NAF++AFTS F           FL DG                 C  ++                  RL  VIVF+++VFG+ YL+  +IP +P S+++ +R+K Y+   
Sbjct:  112 FINAPFQRKHGSLFLNYHDEKSFFTSSQRGYLTYQILTKIDISKDLKGERLGESQDEPTDPSTSSITSDEQLRRKGLSWLLMSDVYEEAFVLHAPSKEEPYFKAMQNGSVKAYNEFISEIELDPRRSLSL----NWERWYKFQPLNKIRDYFGEQIAYYFAWQGTFLTLLWPAVIFGLVVFIYGFID----SISSAPLDWNH----CKVVNFIGQTENVACGMRNGVTL-FFSMVTQWFMSSFDTKMNAFFAVFMSIWGSVFVQIWKRNNSVLSYQWNSDDF-HAIEPDRPEF--RGSKVKEDPITGEDIWISPALARYIKMLASFVFVSFSMLVVVISLMLVTLLKIWMVYNFQCTKEYTFHCWLSAAFLPSILNTLSAMGLGAIYSNLVSRLNSWENHRTESEHNNSLIVKIFAFQMVNTYTSLFYVAFIRPESHGL--QPNGLFGLGTEFKDTCLDDTCSSLLALQLLTHTLIKPFPKFFKDVVLPYFVKLFRLRMYTSRTEARVEIEDDDQANVLVREWLKPSAGDFVLWEMNEKIILFGTTMMFASLFPLAPLLALIIGFVDMRIDAHRLIWFNRKPIPIITNGIGIWLPILTFLQYCAVFTNAFIVAFTSGF--------CSTFLADGAY---------------CTVQN------------------RLIIVIVFQNLVFGLKYLLSSVIPSIPASIKLALRKKRYVVAH 769
[Close]
BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-1 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286])

HSP 1 Score: 231.876 bits (590), Expect = 9.249e-64
Identity = 196/717 (27.34%), Postives = 331/717 (46.16%), Query Frame = 2 
Query:  692 FATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGE-------------------------IGIDRMIDEEIYSAAYPLHEGPAEVP-------------TDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNY-----EKGCRYWNLSDICFYSQMTYL----FDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNE---DCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWF--HRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQ 2686
            F  A F+      +L Y +E +FF+++QR  +  +IL      +  KGE                          G+  ++  ++Y  A+ LH    E P              + + +++L  RR +       W ++YK+QP+  IR+Y+GE+IA YFAW G +   L+PA + G+ VF+YG +     +IS    D N+    C + N+        C   N   + F+S +T      FD     FF++FMS+W   F++ WKR N+ LSY+W++ D+    E  RPE+    ++ + +P+TG +    P   R  +ML   + +    ++V+I ++ V + +I +               + A+   +I+N +  M LG +Y  L  +L  WE HRTE+E  + L VK++ F+ VN Y+S+FY+AF +   +G   + +  FGL  E    C + +C   LA Q+    +        +++ LP  V  F    +       V++   D    L  E  K    + +  E  E I+ FG   +F + FPLAP  ALI  ++++R+DA +L+   R+P+      +G W  IL  +   ++ +NAF++AFTS F           FL DG                 C  ++                  RL  VIVF+++VFG+ YL+  +IP +P S+++ +R+K Y+   
Sbjct:  130 FINAPFQRKHGSLFLNYHDEKSFFTSSQRGYLTYQILTKIDISKDLKGERLGESQDEPTDPSTSSITSDEQLRRKGLSWLLMSDVYEEAFVLHAPSKEEPYFKAMQNGSVKAYNEFISEIELDPRRSLSL----NWERWYKFQPLNKIRDYFGEQIAYYFAWQGTFLTLLWPAVIFGLVVFIYGFID----SISSAPLDWNH----CKVVNFIGQTENVACGMRNGVTL-FFSMVTQWFMSSFDTKMNAFFAVFMSIWGSVFVQIWKRNNSVLSYQWNSDDF-HAIEPDRPEF--RGSKVKEDPITGEDIWISPALARYIKMLASFVFVSFSMLVVVISLMLVTLLKIWMVYNFQCTKEYTFHCWLSAAFLPSILNTLSAMGLGAIYSNLVSRLNSWENHRTESEHNNSLIVKIFAFQMVNTYTSLFYVAFIRPESHGL--QPNGLFGLGTEFKDTCLDDTCSSLLALQLLTHTLIKPFPKFFKDVVLPYFVKLFRLRMYTSRTEARVEIEDDDQANVLVREWLKPSAGDFVLWEMNEKIILFGTTMMFASLFPLAPLLALIIGFVDMRIDAHRLIWFNRKPIPIITNGIGIWLPILTFLQYCAVFTNAFIVAFTSGF--------CSTFLADGAY---------------CTVQN------------------RLIIVIVFQNLVFGLKYLLSSVIPSIPASIKLALRKKRYVVAH 787
[Close]
BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-2 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3])

HSP 1 Score: 119.398 bits (298), Expect = 2.902e-27
Identity = 113/447 (25.28%), Postives = 194/447 (43.40%), Query Frame = 2 
Query:  707 FKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVP----TDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEED--EKPRPEYVA--LATEKRVNPVTGIEEPYFPV--NLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLV 2017
            F  ++ + + G   ++TF S  +R  + ++++      R  KG + +      ++        EG A VP     +++  V   +  + L     KW      QPI+ +++Y+G +IA+YFAWLG  T  L+  SL+GI ++  G    K+    K+                     Y  +SDICF             V F+ F  +W+  +LE WKR  AEL+++W T D  ++   + PRP +    LA     NPV+G  EP++P   +  M+ ++T           + +  +   +  I     L D     S  L +      I   ++I+    +Y +LA  L   E +RT+ E+ED L  K+ LF+FV  + S+FYIAF                 LR+        +  L + +A +++  Q+  NI E  +P ++
Sbjct:  119 FSFEEAQFFSGVEGKNTFLSPMERTIIVKQMMDMM---RAGKGGLSL------KLPRRTITFTEGTAIVPRLISMNVVQNVSALHNTEFLKHLQQKWVFSIDEQPIDQVKDYFGTEIAMYFAWLGHMTTALWFPSLLGILMWFLGGFKYKNSPGDKQDL-------------------YQLISDICF-------------VLFAFFNCIWSTIYLEWWKRVQAELAFKWGTYDATQDSYLQDPRPAFQGDYLAP----NPVSGRLEPFYPAWKHTVMRYVIT------YPITFLCVVGMFAAMLAIFTVQDLADFYFGDSWMLSWLCYFPMIFYALMIVISDKIYRRLALILNDLENYRTDDEYEDFLITKIVLFQFVTAFGSLFYIAFV----------------LRD--------MKRLQETLATLLITRQVTQNIMETVVPFMI 490

HSP 2 Score: 72.0182 bits (175), Expect = 1.526e-12
Identity = 53/190 (27.89%), Postives = 91/190 (47.89%), Query Frame = 2 
Query: 2120 YEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQA 2689
            Y    D++LEM +QFG++ +F  AFPLA   ALINN +EIR+DA KL  + +RP   R +D+G W   + ++  L +I N  LI  +   + ++++               L+W                                ++  ++V EH++     +IDIL+PDVP  ++IE  ++ +  ++A
Sbjct:  619 YARPLDDFLEMFIQFGYVLLFSPAFPLAAVCALINNLIEIRVDAFKLCNTVQRPFGRRVKDIGAWQKAMEILGILGVIVNCALIGQSG--LVQRIWP-------------DLSWGG------------------------------QILIIVVLEHVILASKMIIDILVPDVPHWVRIETAKQEHFRREA 763
[Close]
BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-2 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3])

HSP 1 Score: 119.783 bits (299), Expect = 3.026e-27
Identity = 113/447 (25.28%), Postives = 194/447 (43.40%), Query Frame = 2 
Query:  707 FKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVP----TDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEED--EKPRPEYVA--LATEKRVNPVTGIEEPYFPV--NLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLV 2017
            F  ++ + + G   ++TF S  +R  + ++++      R  KG + +      ++        EG A VP     +++  V   +  + L     KW      QPI+ +++Y+G +IA+YFAWLG  T  L+  SL+GI ++  G    K+    K+                     Y  +SDICF             V F+ F  +W+  +LE WKR  AEL+++W T D  ++   + PRP +    LA     NPV+G  EP++P   +  M+ ++T           + +  +   +  I     L D     S  L +      I   ++I+    +Y +LA  L   E +RT+ E+ED L  K+ LF+FV  + S+FYIAF                 LR+        +  L + +A +++  Q+  NI E  +P ++
Sbjct:  175 FSFEEAQFFSGVEGKNTFLSPMERTIIVKQMMDMM---RAGKGGLSL------KLPRRTITFTEGTAIVPRLISMNVVQNVSALHNTEFLKHLQQKWVFSIDEQPIDQVKDYFGTEIAMYFAWLGHMTTALWFPSLLGILMWFLGGFKYKNSPGDKQDL-------------------YQLISDICF-------------VLFAFFNCIWSTIYLEWWKRVQAELAFKWGTYDATQDSYLQDPRPAFQGDYLAP----NPVSGRLEPFYPAWKHTVMRYVIT------YPITFLCVVGMFAAMLAIFTVQDLADFYFGDSWMLSWLCYFPMIFYALMIVISDKIYRRLALILNDLENYRTDDEYEDFLITKIVLFQFVTAFGSLFYIAFV----------------LRD--------MKRLQETLATLLITRQVTQNIMETVVPFMI 546

HSP 2 Score: 72.4034 bits (176), Expect = 1.342e-12
Identity = 53/190 (27.89%), Postives = 91/190 (47.89%), Query Frame = 2 
Query: 2120 YEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQA 2689
            Y    D++LEM +QFG++ +F  AFPLA   ALINN +EIR+DA KL  + +RP   R +D+G W   + ++  L +I N  LI  +   + ++++               L+W                                ++  ++V EH++     +IDIL+PDVP  ++IE  ++ +  ++A
Sbjct:  675 YARPLDDFLEMFIQFGYVLLFSPAFPLAAVCALINNLIEIRVDAFKLCNTVQRPFGRRVKDIGAWQKAMEILGILGVIVNCALIGQSG--LVQRIWP-------------DLSWGG------------------------------QILIIVVLEHVILASKMIIDILVPDVPHWVRIETAKQEHFRREA 819
[Close]
BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0083806)

HSP 1 Score: 521.546 bits (1342), Expect = 1.462e-170
Identity = 341/851 (40.07%), Postives = 502/851 (58.99%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHT-------PHFS--ERVLKFFLIPNFMKNEL-PYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEI--GIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNT-FKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATE---KRVNPVTGIEEPYFPVNLRMKRMLT----GXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPK--LWSEDYKLLPY--EGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN--FLLDGYVNFTL------------AWAPNNSLSEPCRYRDFRDVNGK-----LTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMT--KNEMGSLKRGESLL 2746
            +  D +R ID+V+ +      IN         TE R+ F   L+  GL  E       K  I F+KIH P  ++  YAE L  R+P++  P  +         FS  + V +FFL   ++  E+ P     F TA +  D+  +YL    +D FF+T  R ++   IL    +  + + ++  GI+R+I E +YSAAYPLH+G            +    R +L+++WA   K+Y+YQP+++I+EY+G KI +YFAWLG YT  L  AS+VG+  F+Y   ++K+Y   K+IC + NT   MCPLC++   C +W+L + C Y+++TYL D+P TVFF++FMS WA  FLE WKR +AE+++RWD   ++  +E PRP+Y+A        RV+ VT I+EP  P   RMK   T     V+ +++    V +  + V    +L A+ +  +P+  S A++ A+ SAA VNL L+  L  +Y  LA  LT+ EM RT+T+F+D LT+K+YL +FVN+Y+SIFYIAFFKG+F G+PG+Y+  F  R E+CS+G CL EL  Q+AIIMVG Q  N I E++LP         + GL+ +   +    + K   W  D+KLL +   GLF EYLEM++Q+GF+TIFVAAFPLAPFFAL+NN LE+RLDA KL+   +RPV++R +D+G W+ IL+ I KLS+I+N F+IAFTSD IP+ VY++  N    LDGY+NFTL            + A + S    CRY DFR          L+  ++ +LA RL FV+VFE+ V  V  L+   IPD+   L+ ++RR+ Y+  + +++    +      KR  S+L
Sbjct:   37 FFEDCVRSIDFVLAYR-----INAHEPTELENTEKRRVFEANLISQGLEVESSQ----KDQIWFVKIHAPLEVLRRYAEILKLRMPMKEIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRF-TAIYSRDK--EYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEI---------TETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCDW---CNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPF-WRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQEAHRARFERAKRSSSVL 862
[Close]
BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0334921)

HSP 1 Score: 521.546 bits (1342), Expect = 1.462e-170
Identity = 341/851 (40.07%), Postives = 502/851 (58.99%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHT-------PHFS--ERVLKFFLIPNFMKNEL-PYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEI--GIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNT-FKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATE---KRVNPVTGIEEPYFPVNLRMKRMLT----GXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPK--LWSEDYKLLPY--EGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN--FLLDGYVNFTL------------AWAPNNSLSEPCRYRDFRDVNGK-----LTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMT--KNEMGSLKRGESLL 2746
            +  D +R ID+V+ +      IN         TE R+ F   L+  GL  E       K  I F+KIH P  ++  YAE L  R+P++  P  +         FS  + V +FFL   ++  E+ P     F TA +  D+  +YL    +D FF+T  R ++   IL    +  + + ++  GI+R+I E +YSAAYPLH+G            +    R +L+++WA   K+Y+YQP+++I+EY+G KI +YFAWLG YT  L  AS+VG+  F+Y   ++K+Y   K+IC + NT   MCPLC++   C +W+L + C Y+++TYL D+P TVFF++FMS WA  FLE WKR +AE+++RWD   ++  +E PRP+Y+A        RV+ VT I+EP  P   RMK   T     V+ +++    V +  + V    +L A+ +  +P+  S A++ A+ SAA VNL L+  L  +Y  LA  LT+ EM RT+T+F+D LT+K+YL +FVN+Y+SIFYIAFFKG+F G+PG+Y+  F  R E+CS+G CL EL  Q+AIIMVG Q  N I E++LP         + GL+ +   +    + K   W  D+KLL +   GLF EYLEM++Q+GF+TIFVAAFPLAPFFAL+NN LE+RLDA KL+   +RPV++R +D+G W+ IL+ I KLS+I+N F+IAFTSD IP+ VY++  N    LDGY+NFTL            + A + S    CRY DFR          L+  ++ +LA RL FV+VFE+ V  V  L+   IPD+   L+ ++RR+ Y+  + +++    +      KR  S+L
Sbjct:   37 FFEDCVRSIDFVLAYR-----INAHEPTELENTEKRRVFEANLISQGLEVESSQ----KDQIWFVKIHAPLEVLRRYAEILKLRMPMKEIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRF-TAIYSRDK--EYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEI---------TETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCDW---CNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPF-WRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQEAHRARFERAKRSSSVL 862
[Close]
BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0083805)

HSP 1 Score: 521.546 bits (1342), Expect = 7.651e-169
Identity = 342/857 (39.91%), Postives = 504/857 (58.81%), Query Frame = 2 
Query:  311 ELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHT-------PHFS--ERVLKFFLIPNFMKNEL-PYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEI--GIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNT-FKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATE---KRVNPVTGIEEPYFPVNLRMKRMLT----GXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPK--LWSEDYKLLPY--EGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN--FLLDGYVNFTL------------AWAPNNSLSEPCRYRDFRDVNGK-----LTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMT--KNEMGSLKRGESLL 2746
            E+    +  D +R ID+V+ +      IN         TE R+ F   L+  GL  E       K  I F+KIH P  ++  YAE L  R+P++  P  +         FS  + V +FFL   ++  E+ P     F TA +  D+  +YL    +D FF+T  R ++   IL    +  + + ++  GI+R+I E +YSAAYPLH+G            +    R +L+++WA   K+Y+YQP+++I+EY+G KI +YFAWLG YT  L  AS+VG+  F+Y   ++K+Y   K+IC + NT   MCPLC++   C +W+L + C Y+++TYL D+P TVFF++FMS WA  FLE WKR +AE+++RWD   ++  +E PRP+Y+A        RV+ VT I+EP  P   RMK   T     V+ +++    V +  + V    +L A+ +  +P+  S A++ A+ SAA VNL L+  L  +Y  LA  LT+ EM RT+T+F+D LT+K+YL +FVN+Y+SIFYIAFFKG+F G+PG+Y+  F  R E+CS+G CL EL  Q+AIIMVG Q  N I E++LP         + GL+ +   +    + K   W  D+KLL +   GLF EYLEM++Q+GF+TIFVAAFPLAPFFAL+NN LE+RLDA KL+   +RPV++R +D+G W+ IL+ I KLS+I+N F+IAFTSD IP+ VY++  N    LDGY+NFTL            + A + S    CRY DFR          L+  ++ +LA RL FV+VFE+ V  V  L+   IPD+   L+ ++RR+ Y+  + +++    +      KR  S+L
Sbjct:  180 EINTSLFFEDCVRSIDFVLAYR-----INAHEPTELENTEKRRVFEANLISQGLEVESSQ----KDQIWFVKIHAPLEVLRRYAEILKLRMPMKEIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRF-TAIYSRDK--EYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEI---------TETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCDW---CNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPF-WRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQEAHRARFERAKRSSSVL 1011
[Close]
BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0334922)

HSP 1 Score: 512.686 bits (1319), Expect = 7.587e-167
Identity = 340/875 (38.86%), Postives = 501/875 (57.26%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQ-------------------------------IGPPHTPHFS--ERVLKFFLIPNFMKNEL-PYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEI--GIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNT-FKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATE---KRVNPVTGIEEPYFPVNLRMKRMLT----GXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPK--LWSEDYKLLPY--EGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN--FLLDGYVNFTL------------AWAPNNSLSEPCRYRDFRDVNGK-----LTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMT--KNEMGSLKRGESLL 2746
            +  D +R ID+V+ +      IN         TE R+ F   L+  GL  E       K  I F+KIH P  ++  YAE L  R+P++                               +       FS  + V +FFL   ++  E+ P     F TA +  D+  +YL    +D FF+T  R ++   IL    +  + + ++  GI+R+I E +YSAAYPLH+G            +    R +L+++WA   K+Y+YQP+++I+EY+G KI +YFAWLG YT  L  AS+VG+  F+Y   ++K+Y   K+IC + NT   MCPLC++   C +W+L + C Y+++TYL D+P TVFF++FMS WA  FLE WKR +AE+++RWD   ++  +E PRP+Y+A        RV+ VT I+EP  P   RMK   T     V+ +++    V +  + V    +L A+ +  +P+  S A++ A+ SAA VNL L+  L  +Y  LA  LT+ EM RT+T+F+D LT+K+YL +FVN+Y+SIFYIAFFKG+F G+PG+Y+  F  R E+CS+G CL EL  Q+AIIMVG Q  N I E++LP         + GL+ +   +    + K   W  D+KLL +   GLF EYLEM++Q+GF+TIFVAAFPLAPFFAL+NN LE+RLDA KL+   +RPV++R +D+G W+ IL+ I KLS+I+N F+IAFTSD IP+ VY++  N    LDGY+NFTL            + A + S    CRY DFR          L+  ++ +LA RL FV+VFE+ V  V  L+   IPD+   L+ ++RR+ Y+  + +++    +      KR  S+L
Sbjct:   37 FFEDCVRSIDFVLAYR-----INAHEPTELENTEKRRVFEANLISQGLEVESSQ----KDQIWFVKIHAPLEVLRRYAEILKLRMPMKESLCNLRISERSNRLRNAAHYLTNKIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRF-TAIYSRDK--EYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEI---------TETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCDW---CNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPF-WRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQEAHRARFERAKRSSSVL 886
[Close]
BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0302492)

HSP 1 Score: 512.301 bits (1318), Expect = 6.207e-165
Identity = 338/881 (38.37%), Postives = 503/881 (57.09%), Query Frame = 2 
Query:  311 ELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELP-------YSPDCFA---------------------------TAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEI--GIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNT-FKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATE---KRVNPVTGIEEPYFPVNLRMKRMLT----GXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPK--LWSEDYKLLPY--EGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN--FLLDGYVNFTL------------AWAPNNSLSEPCRYRDFRDVNGK-----LTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMT--KNEMGSLKRGESLL 2746
            E+    +  D +R ID+V+ +      IN         TE R+ F   L+  GL  E       K  I F+KIH P  ++  YAE L  R+P++    +    SER  +     +++ N++P        +   F+                           TA +  D+  +YL    +D FF+T  R ++   IL    +  + + ++  GI+R+I E +YSAAYPLH+G            +    R +L+++WA   K+Y+YQP+++I+EY+G KI +YFAWLG YT  L  AS+VG+  F+Y   ++K+Y   K+IC + NT   MCPLC++   C +W+L + C Y+++TYL D+P TVFF++FMS WA  FLE WKR +AE+++RWD   ++  +E PRP+Y+A        RV+ VT I+EP  P   RMK   T     V+ +++    V +  + V    +L A+ +  +P+  S A++ A+ SAA VNL L+  L  +Y  LA  LT+ EM RT+T+F+D LT+K+YL +FVN+Y+SIFYIAFFKG+F G+PG+Y+  F  R E+CS+G CL EL  Q+AIIMVG Q  N I E++LP         + GL+ +   +    + K   W  D+KLL +   GLF EYLEM++Q+GF+TIFVAAFPLAPFFAL+NN LE+RLDA KL+   +RPV++R +D+G W+ IL+ I KLS+I+N F+IAFTSD IP+ VY++  N    LDGY+NFTL            + A + S    CRY DFR          L+  ++ +LA RL FV+VFE+ V  V  L+   IPD+   L+ ++RR+ Y+  + +++    +      KR  S+L
Sbjct:  180 EINTSLFFEDCVRSIDFVLAYR-----INAHEPTELENTEKRRVFEANLISQGLEVESSQ----KDQIWFVKIHAPLEVLRRYAEILKLRMPMKESLCNL-RISERSNRLRNAAHYLTNKIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAIYSRDK--EYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEI---------TETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCDW---CNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPF-WRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQEAHRARFERAKRSSSVL 1035
[Close]
BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 794.653 bits (2051), Expect = 0.000e+0
Identity = 421/835 (50.42%), Postives = 578/835 (69.22%), Query Frame = 2 
Query:  269 ESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEK--------------------LLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFD--NPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAP---NNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLN 2698
            E  A  P+  T         Y  DG  +ID+V+VWE           +        +   E+                    L   GL  E+E   S K  I+++K+H P++++  YAE L  R PLQ  P    + S RVL+   +PN MK+ +P  P  + T AF+  ++EK+LG  + + +F++TQRH++  EILA T YGR+ + E+G+ R++ +  ++ A+PLHEGP ++P+    + D  N+RQ+L+ YWA W K+ KYQP+++IREY+GEKIA+YFAWLG YTAWL PA+LVG  VFV GILTM S T +KEIC++   + MCPLC   + C+ WN+SDIC  +++ YLFDHPGTVFFS+FMS+WAV FLE WKRKNA L++ WD +D+ E++E PRPE+ A+A     NPVTG++EPYFP   R+ RMLTG M IV+M  +V+IF++ VIIYR ++++ +F+  + +LR++A   A++S+ +VNL LI+ +G VY  LA +LT+WEMHRT+T++ED  T KV++F+FVNFYSS FY+AFFKGRF GYPG Y   FG+RNEDC  G CL ELA+Q+ IIMVG Q+INNIQE  +PK+  W  R K+ L + V+ + K  EP+ W +DY+L+P EGLFDEYLE+++QFGFITIFVAAFPLAP FAL+NNW+E+RLDA K V   RRPVAERAQ +G WFIIL  +  +S++ NAFLIAFTSDF+P+ +Y+Y  N  L GYVNFTLA++P   N+S    CRY+ FRD NGK    YW LLA+RL F+I FEH+VF V  +ID ++PD+PESLQ++++R+ Y+AKQAL +
Sbjct:   61 EQTASAPVHHTGN-------YFRDGQTKIDFVLVWEVKVRRKRRSRGQAEASEGAAEPAQEESRSERRKAQLARWRDKFILNLQTAGLLMEKEESSSVKKTIHYLKLHAPWDVLVYYAEELCLRAPLQAQPHPDFNTSARVLQKLWVPNIMKDSVPNRPVDYYTCAFRKSKMEKFLGSDDRENYFTSTQRHRIVYEILARTAYGRRKRAEVGVARLLRDGAFTGAFPLHEGPFKLPS-CDTQPDQLNKRQVLYHYWASWLKWCKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAALVGTCVFVSGILTMGSNTPAKEICESGGLYLMCPLC---ETCKPWNMSDICPMAKVGYLFDHPGTVFFSVFMSLWAVTFLEYWKRKNATLAHHWDCMDFHEDEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMFETGSSVLRTQAGNIANISSTLVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLCIIMVGKQLINNIQEFVIPKIKAW--RQKRALAS-VKKAQKTQEPERWEQDYELIPCEGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWVEVRLDAHKFVCEYRRPVAERAQHIGVWFIILEALSHVSVVVNAFLIAFTSDFLPRLLYQYKFNNDLHGYVNFTLAYSPPSYNHSSHTVCRYKAFRDENGKYKLVYWELLAVRLGFIIAFEHVVFFVLRVIDWMVPDIPESLQLKIKRERYLAKQALAD 881
[Close]
BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 794.653 bits (2051), Expect = 0.000e+0
Identity = 421/835 (50.42%), Postives = 578/835 (69.22%), Query Frame = 2 
Query:  269 ESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEK--------------------LLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFD--NPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAP---NNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLN 2698
            E  A  P+  T         Y  DG  +ID+V+VWE           +        +   E+                    L   GL  E+E   S K  I+++K+H P++++  YAE L  R PLQ  P    + S RVL+   +PN MK+ +P  P  + T AF+  ++EK+LG  + + +F++TQRH++  EILA T YGR+ + E+G+ R++ +  ++ A+PLHEGP ++P+    + D  N+RQ+L+ YWA W K+ KYQP+++IREY+GEKIA+YFAWLG YTAWL PA+LVG  VFV GILTM S T +KEIC++   + MCPLC   + C+ WN+SDIC  +++ YLFDHPGTVFFS+FMS+WAV FLE WKRKNA L++ WD +D+ E++E PRPE+ A+A     NPVTG++EPYFP   R+ RMLTG M IV+M  +V+IF++ VIIYR ++++ +F+  + +LR++A   A++S+ +VNL LI+ +G VY  LA +LT+WEMHRT+T++ED  T KV++F+FVNFYSS FY+AFFKGRF GYPG Y   FG+RNEDC  G CL ELA+Q+ IIMVG Q+INNIQE  +PK+  W  R K+ L + V+ + K  EP+ W +DY+L+P EGLFDEYLE+++QFGFITIFVAAFPLAP FAL+NNW+E+RLDA K V   RRPVAERAQ +G WFIIL  +  +S++ NAFLIAFTSDF+P+ +Y+Y  N  L GYVNFTLA++P   N+S    CRY+ FRD NGK    YW LLA+RL F+I FEH+VF V  +ID ++PD+PESLQ++++R+ Y+AKQAL +
Sbjct:   61 EQTASAPVHHTGN-------YFRDGQTKIDFVLVWEVKVRRKRRSRGQAEASEGAAEPAQEESRSERRKAQLARWRDKFILNLQTAGLLMEKEESSSVKKTIHYLKLHAPWDVLVYYAEELCLRAPLQAQPHPDFNTSARVLQKLWVPNIMKDSVPNRPVDYYTCAFRKSKMEKFLGSDDRENYFTSTQRHRIVYEILARTAYGRRKRAEVGVARLLRDGAFTGAFPLHEGPFKLPS-CDTQPDQLNKRQVLYHYWASWLKWCKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAALVGTCVFVSGILTMGSNTPAKEICESGGLYLMCPLC---ETCKPWNMSDICPMAKVGYLFDHPGTVFFSVFMSLWAVTFLEYWKRKNATLAHHWDCMDFHEDEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMFETGSSVLRTQAGNIANISSTLVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLCIIMVGKQLINNIQEFVIPKIKAW--RQKRALAS-VKKAQKTQEPERWEQDYELIPCEGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWVEVRLDAHKFVCEYRRPVAERAQHIGVWFIILEALSHVSVVVNAFLIAFTSDFLPRLLYQYKFNNDLHGYVNFTLAYSPPSYNHSSHTVCRYKAFRDENGKYKLVYWELLAVRLGFIIAFEHVVFFVLRVIDWMVPDIPESLQLKIKRERYLAKQALAD 881
[Close]
BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 714.916 bits (1844), Expect = 0.000e+0
Identity = 365/640 (57.03%), Postives = 489/640 (76.41%), Query Frame = 2 
Query:  794 EILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFD--NPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAP---NNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLN 2698
            EILA T YGR+ + E+G+ R++ +  ++ A+PLHEGP ++P+    + D  N+RQ+L+ YWA W K+ KYQP+++IREY+GEKIA+YFAWLG YTAWL PA+LVG  VFV GILTM S T +KEIC++   + MCPLC   + C+ WN+SDIC  +++ YLFDHPGTVFFS+FMS+WAV FLE WKRKNA L++ WD +D+ E++E PRPE+ A+A     NPVTG++EPYFP   R+ RMLTG M IV+M  +V+IF++ VIIYR ++++ +F+  + +LR++A   A++S+ +VNL LI+ +G VY  LA +LT+WEMHRT+T++ED  T KV++F+FVNFYSS FY+AFFKGRF GYPG Y   FG+RNEDC  G CL ELA+Q+ IIMVG Q+INNIQE  +PK+  W  R K+ L + V+ + K  EP+ W +DY+L+P EGLFDEYLE+++QFGFITIFVAAFPLAP FAL+NNW+E+RLDA K V   RRPVAERAQ +G WFIIL  +  +S++ NAFLIAFTSDF+P+ +Y+Y  N  L GYVNFTLA++P   N+S    CRY+ FRD NGK    YW LLA+RL F+I FEH+VF V  +ID ++PD+PESLQ++++R+ Y+AKQAL +
Sbjct:    3 EILARTAYGRRKRAEVGVARLLRDGAFTGAFPLHEGPFKLPS-CDTQPDQLNKRQVLYHYWASWLKWCKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAALVGTCVFVSGILTMGSNTPAKEICESGGLYLMCPLC---ETCKPWNMSDICPMAKVGYLFDHPGTVFFSVFMSLWAVTFLEYWKRKNATLAHHWDCMDFHEDEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMFETGSSVLRTQAGNIANISSTLVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLCIIMVGKQLINNIQEFVIPKIKAW--RQKRALAS-VKKAQKTQEPERWEQDYELIPCEGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWVEVRLDAHKFVCEYRRPVAERAQHIGVWFIILEALSHVSVVVNAFLIAFTSDFLPRLLYQYKFNNDLHGYVNFTLAYSPPSYNHSSHTVCRYKAFRDENGKYKLVYWELLAVRLGFIIAFEHVVFFVLRVIDWMVPDIPESLQLKIKRERYLAKQALAD 635
[Close]
BLAST of Anoctamin vs. Ensembl Zebrafish
Match: si:dkey-83h2.5 (si:dkey-83h2.5 [Source:ZFIN;Acc:ZDB-GENE-131125-81])

HSP 1 Score: 708.753 bits (1828), Expect = 0.000e+0
Identity = 398/805 (49.44%), Postives = 552/805 (68.57%), Query Frame = 2 
Query:  335 NDGIRRIDYVIVWEQDRIAI-NVDPEXXXXXXXX------XXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIF-------ASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFK-KGLNNMVQLSGKDVEPKL--WSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSE--PCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            +DG+  ID+V+VWE+    + + D +     +        R  F  KL + GL  E +     K    ++ +  P+N++C YAE ++ RVPLQ+      ++SE +L+   IPN M  ++P  P  + T  F+T +LE++LG+ N+DTFF TTQRHQ+  EILA T YG   +GE+GI R++ E++ +AA+PLHEGP ++P        L N RQIL  YWA+W+ + KYQP+++IREY+GEKIA+YFAWLG YT WL PA++VG  +F++GI  M +   ++E+C + N F MCPLCN    C +WNLS IC+  +   LFD+ GTVFFSIFMS+WAV FLE WKR ++ LS+RWD  ++EE +E+PRPE+ ALA     NPVTG EEPYFP   R+ R LTG M I++M  IV+IF++ +I+YR +++I ++     RS++  F       AS++ +++NL++I+ L  +Y  LA  LT+WEMHRT+TE+E+   +KV++F+FVNFYSS  YIAFFKGRF GYPG Y+   G+RNEDC    CL ELAQ++ +IMVG Q+I+NIQE  LPKL TW+H+ K K   +   +   D   ++  W  DY+LL  EGLFDEYLEM++QFGFITIFVAA PLAP FALINNW+E+RLDA K V   RRPV ERAQD+G W  IL  I  L++ISNAFLIAFTSDF+P+  Y+Y+    + GY+NFTL+ AP N       CRYR  RD  G+ T+ Y+ LLAIRL+FVI+FEH+V  +  +ID ++PD+PE ++I+++R++YMAK+AL
Sbjct:   43 SDGVTTIDFVLVWEESGSPLKSADGDELSFSSSRDTHRKWRTEFLSKLQEAGLHQEMKEVVQGKTKTTYVLLSAPWNVLCYYAEEISLRVPLQVVTTPISNWSETILEKLHIPNIMAQDVPNYPPDYYTCPFRTTKLERFLGHENKDTFFKTTQRHQILYEILARTPYGALKRGEVGIGRLVSEKVLTAAFPLHEGPFQLPKTQEDPQCL-NMRQILHHYWARWACWRKYQPLDHIREYFGEKIALYFAWLGFYTGWLLPAAVVGFIIFLFGIWLMVTDVPAEELCSSGNAFIMCPLCNI---CSHWNLSSICYTYKAGLLFDNGGTVFFSIFMSLWAVTFLEYWKRTSSILSHRWDCSEFEEIEERPRPEFTALAPMTVRNPVTGAEEPYFPEARRLSRTLTGNMVIILMISIVLIFLMAIILYRTILSIIIY-----RSQSAFFIFSAGRIASLTGSMLNLLVILLLSRLYTYLAQCLTRWEMHRTQTEYENAFILKVFIFQFVNFYSSPVYIAFFKGRFVGYPGSYNTLLGIRNEDCGASGCLIELAQELLVIMVGKQVISNIQEFVLPKLKTWWHKRKLKPARSQEVIDEPDTNSQINPWENDYQLLVCEGLFDEYLEMVLQFGFITIFVAACPLAPLFALINNWVEVRLDAQKFVCEYRRPVVERAQDIGIWLTILQFISYLAVISNAFLIAFTSDFLPRLFYRYTAGS-MSGYINFTLSVAPANFTQNEMSCRYRGLRDEKGQNTQDYYHLLAIRLSFVIIFEHVVLLIGRIIDWIVPDIPEEVEIKIKREHYMAKEAL 837
[Close]
BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano3 (anoctamin 3 [Source:ZFIN;Acc:ZDB-GENE-111031-3])

HSP 1 Score: 528.865 bits (1361), Expect = 1.888e-172
Identity = 348/873 (39.86%), Postives = 497/873 (56.93%), Query Frame = 2 
Query:  212 FDCQMEKLQLINLKKDKNKESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQ------------IGPPHTPHFSERVLKFFLIPNFMKNELPYSPD-----CFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEG--PAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPL--FDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYS-LFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPY--EGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYK----------YSHNFLLDGYVN-----FTLAWAPNNSL-SEPCRYRDFRDVNG-----KLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            F+ + ++  L+  K     +  A    +K    E        DG +RIDY++V+++    +             R  F   L   GL  E+E   +   ++ F+KIH P++ +C YAE +N R+P +            +G      F  R LK +L  N MK +    PD     C+ TA F   ++  +    N +TFFS + R ++   +L  T Y    K ++GI+R++    Y AA+P HEG   +  P    G     N R +L+E WA+W  +YKYQP++ IR Y+GEKI +YFAWLG YT  L PA+LVG+FVF+YG+ TM S  +SKEIC+ N T  MCP+C  E  C  W LSD C Y+++T+LFD+ GTVFF+IFM++WA  FLE WKR+ AEL+Y WD +D+EEE+E+ RP++ A  + K RVNP++G  EP+ P+  ++ R++  V  I  M  +V+  +  V+++R++       F    ++       S +   +N ++IMSL +VYEK+AY LT  E  RTE+E+E+   +K++LF+FVN  SS FYIAFF GRF G PG Y+ LF   R E+C    CL +L  QM +IMV  QI NN  E+  P L  W+ R K  +    + S    E   W  D+ L P    GL DEYLEM++QFGF TIFVAAFPLAP  AL+NN +EIRLDA K V   RRP+  RA D+G W  +L  I  +++I+NAF+IA TSD+IP+ VY           Y H   L GY+N     F +    N S  ++ CRYRD+R         + T  +W +LA RL F+IVFEH+VFG+   I  +IPD+P+ L   MRR+ Y+ ++ +
Sbjct:  117 FEPKTDETLLVQQKPVSRGKLEARTDSVKGKNLETPSGLMFRDGKKRIDYILVYKKSSPQVE-----------KRCTFERNLRAEGLMLEKEPSLTNSDIM-FVKIHAPWDTLCKYAEQMNIRMPFRKKCYFTDWKKKAMGSRFQLRF--RQLKSWLPRNPMKLDKEALPDLVETDCY-TAPFCRARMHHFT-INNRETFFSNSTRSRIVHHVLQRTKY-EDGKSKMGINRLLGNSTYEAAFPPHEGCYKSRHPIKTHGAQ---NHRHLLYERWARWGIWYKYQPLDLIRRYFGEKIGLYFAWLGWYTGMLIPAALVGLFVFLYGLFTMDSSQVSKEICEANTTV-MCPMC--EGNCSSWTLSDSCVYAKVTHLFDNGGTVFFAIFMAIWATVFLEFWKRRRAELTYDWDLIDWEEEEEELRPQFEAKYSRKERVNPISGKPEPFQPLTDKLSRLMVSVSGIFFMISLVLTAVFAVVVFRLIAMEKFVSFQWEFVKKNWQFATSGTGVCINFMIIMSLNVVYEKVAYLLTNLEHPRTESEWENSFALKMFLFQFVNLNSSTFYIAFFLGRFAGRPGDYNKLFNRWRMEECHPSGCLIDLCLQMGVIMVLKQIWNNFMELGYPLLQNWWSRRK--MKRAGEQSNSKEELPQWDRDWNLQPMNAHGLVDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGVLEGIGVVAVITNAFVIAITSDYIPRFVYAIKYGPCVDKGYRHEKCLRGYLNNSLSVFDMGELRNGSYENQYCRYRDYRAPPWSPEPYEFTLQFWHVLAARLAFIIVFEHLVFGIKTFIAHMIPDMPKDLCDRMRREKYLMQEMV 964
[Close]
BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO4 (major histocompatibility complex class I-related gene protein-like [Source:Xenbase;Acc:XB-GENE-5756215])

HSP 1 Score: 511.146 bits (1315), Expect = 2.071e-167
Identity = 334/811 (41.18%), Postives = 476/811 (58.69%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFF-----LIPN----FMKNELP--YSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKY-SLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLL-DGYVNFTLAWAPNNSLSEPCRYRDFRDVNG-----KLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            + NDG RRIDY++V+ +  +            +E R+ F   +   GL  E+E       +I F+K+H P+ ++  YAE +N R+P +       ++  R  KF      L+P       K ++P     DC+ TA F   ++  ++   N+DTFF+   R ++   IL    Y  + K +IG++R++    Y AA+PLHEG       +       N R +LFE WA W  +YKYQP++ +R Y+GEKI +YFAWLG YT  LFPA++VG+FVF+YG+ T+ S  +S+EIC   N   MCPLC  +K C Y  LSD C Y+++T+LFD+  TVFF++FM+VWA  FLE WKR+ A ++Y WD +D+EEE+E+ RP++ A  ++K RVNP++G  EPY     +  R++     I  ++  +I  +F I +     +     F   L+R+ + +  + +A  +N  +IM L L YE++A  LT  E  RTE+E+E+  T+K++LF+FVN  SS FYIAFF GRF G PG Y  L    R E+C    CL +L  QM IIMV  Q  NN  E+  P +  W+ R K  L     + GK   P+ W +DY L P    GLF+EYLEMI+QFGF TIFVAAFPLAP  AL+NN +EIRLDA K +   RRP+A RA+D+G W+ IL  I  LS+I+NAF+IA TSDFIP+ VY Y +      G     L       +S   RYRD+RD          T  +W +LA RL F+IVFEH+VF + +LI  LIPD+P+ L+  MRR+ Y+ ++ +
Sbjct:   26 FFNDGKRRIDYILVYRKTSLQ-----------SEKREIFERNIRAEGLHLEKESSIVNSDII-FVKLHAPWEVLGRYAELMNVRMPFR----RKIYYLHRRYKFMSRFRGLLPKKPMRLDKEKIPDLEENDCY-TAPFSQQRIHHFI-INNKDTFFNNATRTRIVHHILQRVKY-EEGKNKIGLNRLLTNCTYEAAFPLHEGSYRSKNSIKTH-GAENHRHLLFECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAIVGLFVFLYGMFTLDSCQVSREICQATN-ITMCPLC--DKYCPYMRLSDSCIYAKVTHLFDNSATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERVNPISGKPEPYQAFADKCSRLVVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNL-YERVALFLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGRPGAYLRLINKWRLEECHPSGCLIDLCLQMGIIMVLKQTWNNFMELGYPLIQNWWTRRK--LRQEHGIHGKTALPQ-WEKDYNLQPINPYGLFEEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFITQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAVTSDFIPRLVYAYKYGPCAGQGRAGEKLI------ISFSSRYRDYRDPPSAPEPYAYTLQFWHVLAARLAFIIVFEHLVFFIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 803
[Close]
BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO4 (major histocompatibility complex class I-related gene protein-like [Source:Xenbase;Acc:XB-GENE-5756215])

HSP 1 Score: 509.99 bits (1312), Expect = 5.911e-167
Identity = 332/830 (40.00%), Postives = 480/830 (57.83%), Query Frame = 2 
Query:  314 LCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSP--------------DCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKY-SLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----------FLLDGYVNFTLAW-------APNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            +C   + NDG RRIDY++V+ +  +            +E R+ F   +   GL  E+E       +I F+K+H P+ ++  YAE +N R+P +       ++  R  KF  + +  +  LP  P              DC+ TA F   ++  ++   N+DTFF+   R ++   IL    Y  + K +IG++R++    Y AA+PLHEG       +       N R +LFE WA W  +YKYQP++ +R Y+GEKI +YFAWLG YT  LFPA++VG+FVF+YG+ T+ S  +S+EIC   N   MCPLC  +K C Y  LSD C Y+++T+LFD+  TVFF++FM+VWA  FLE WKR+ A ++Y WD +D+EEE+E+ RP++ A  ++K RVNP++G  EPY     +  R++     I  ++  +I  +F I +     +     F   L+R+ + +  + +A  +N  +IM L ++YE++A  LT  E  RTE+E+E+  T+K++LF+FVN  SS FYIAFF GRF G PG Y  L    R E+C    CL +L  QM IIMV  Q  NN  E+  P +  W+ R K  L     + GK   P+ W +DY L P    GLF+EYLEMI+QFGF TIFVAAFPLAP  AL+NN +EIRLDA K +   RRP+A RA+D+G W+ IL  I  LS+I+NAF+IA TSDFIP+ VY Y +             + GYVN +L+          +NS   P     +       T  +W +LA RL F+IVFEH+VF + +LI  LIPD+P+ L+  MRR+ Y+ ++ +
Sbjct:   10 VCCGLFFNDGKRRIDYILVYRKTSLQ-----------SEKREIFERNIRAEGLHLEKESSIVNSDII-FVKLHAPWEVLGRYAELMNVRMPFR----RKIYYLHRRYKF--MSSRFRGLLPKKPMRLDKEKIPDLEENDCY-TAPFSQQRIHHFI-INNKDTFFNNATRTRIVHHILQRVKY-EEGKNKIGLNRLLTNCTYEAAFPLHEGSYRSKNSIKTH-GAENHRHLLFECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAIVGLFVFLYGMFTLDSCQVSREICQATN-ITMCPLC--DKYCPYMRLSDSCIYAKVTHLFDNSATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERVNPISGKPEPYQAFADKCSRLVVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYERVALFLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGRPGAYLRLINKWRLEECHPSGCLIDLCLQMGIIMVLKQTWNNFMELGYPLIQNWWTRRK--LRQEHGIHGKTALPQ-WEKDYNLQPINPYGLFEEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFITQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAVTSDFIPRLVYAYKYGPCAGQGRAGEKCMVGYVNASLSVFLVTDFENHSNSSHPPSAPEPY-----AYTLQFWHVLAARLAFIIVFEHLVFFIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 806
[Close]
BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO5 (anoctamin 5 [Source:NCBI gene;Acc:100489787])

HSP 1 Score: 505.753 bits (1301), Expect = 7.116e-165
Identity = 328/826 (39.71%), Postives = 472/826 (57.14%), Query Frame = 2 
Query:  338 DGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXK-MMINFIKIHIPFNIMCIYAEALNFRVPLQIG--PPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQT-KGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTN--NTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKP--RPEYVALATEKRVNPVTGIEEPYFPVNLRMKRM-LTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKA------LIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFG-LRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGL--FDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----FLLDGYVNFTLAWAPNNSLSE------------PCRYRDFRDVNG-----KLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            DG RRID+V+ + +D      D E++         F   L K GL  E E ++  +     F+KIH P+ ++  YAE LN ++PL+       + +    VLK F +P     E+ Y    + TA F+ D+ E +     E  FF+ + R+++   IL+   YG +  K + GI R++    Y  AYPLH+      TD          R  L+ +WAK+++FYK QP++ IR+YYGEKI IYFAWLG YT  LF A++VG F F+YG +TM     SKEICD N      MCPLC+  K C +W L+  C  SQ +++FD+  T+FF+IFM +W   FLE WKR+ A L Y WD VD+EEE ++   RPEY +  TEK+ NPVT   EPY P   +  R   +G   +  + + +  II II   ++       + DN L            +  SV+A+++N + IM L  +YE++A  +T  E+ RT  E+E+ LT+K++LF+FVN+YSS FY+AFFKG+F GYP  YS  FG  RNE+C    CL EL  Q+ I+M G QI  NIQE F+P    W  R +K  N+   L  +      W  D  L  + GL  F+EYLEM+VQFGFIT+FVA+FPLAP  AL+NN LEIR+D+ KL    +RPVA +A  +G W  ILN I  LS+++NAF++AFTSD IP+ VY Y+++      + GY+  +L+    +   E             CRYRD+R   G     ++T  YW +LA ++ F+I+ EH+VF V + +  LIPDVP  ++  ++R+ ++ ++ L
Sbjct:   25 DGSRRIDFVLSYTED---TGKDAEKKAERRRE---FELNLQKSGLELETEDKKESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLKADDLKDDSENILSHVLKLFKLPQ----EVMYPEPDYFTAPFRKDKQELFRTEEREK-FFTPSTRNRIVYYILSRCHYGEEEGKKKFGIKRLLTNGSYLDAYPLHDCQYWKKTDERN-----CERYTLYTHWAKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMDDSISSKEICDPNIGGQIIMCPLCD--KRCEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYESKCTEKKKNPVTQEMEPYLPATSKAARFCFSGATVLFWIALIIASIIAIIVYRLWVYAAFASIMDNNLALKPVSNLLTPQLATSVTASVLNFVTIMILNFLYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPADYSYLFGKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKR-RKARNHPQNLYSR------WEHDGDLQTFGGLGLFNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPMSGYIGSSLSVFNVSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQYWHILAAKMAFIIIMEHVVFLVKFFVAWLIPDVPSEVKARVKREKFLTQKIL 825
[Close]
BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO5 (anoctamin 5 [Source:NCBI gene;Acc:100489787])

HSP 1 Score: 505.753 bits (1301), Expect = 1.004e-164
Identity = 329/827 (39.78%), Postives = 473/827 (57.19%), Query Frame = 2 
Query:  338 DGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXK-MMINFIKIHIPFNIMCIYAEALNFRVPLQIG--PPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQT-KGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWN-RRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTN--NTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKP--RPEYVALATEKRVNPVTGIEEPYFPVNLRMKRM-LTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKA------LIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFG-LRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGL--FDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----FLLDGYVNFTLAWAPNNSLSE------------PCRYRDFRDVNG-----KLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            DG RRID+V+ + +D      D E++         F   L K GL  E E ++  +     F+KIH P+ ++  YAE LN ++PL+       + +    VLK F +P     E+ Y    + TA F+ D+ E +     E  FF+ + R+++   IL+   YG +  K + GI R++    Y  AYPLH+           K D  N  R  L+ +WAK+++FYK QP++ IR+YYGEKI IYFAWLG YT  LF A++VG F F+YG +TM     SKEICD N      MCPLC+  K C +W L+  C  SQ +++FD+  T+FF+IFM +W   FLE WKR+ A L Y WD VD+EEE ++   RPEY +  TEK+ NPVT   EPY P   +  R   +G   +  + + +  II II   ++       + DN L            +  SV+A+++N + IM L  +YE++A  +T  E+ RT  E+E+ LT+K++LF+FVN+YSS FY+AFFKG+F GYP  YS  FG  RNE+C    CL EL  Q+ I+M G QI  NIQE F+P    W  R +K  N+   L  +      W  D  L  + GL  F+EYLEM+VQFGFIT+FVA+FPLAP  AL+NN LEIR+D+ KL    +RPVA +A  +G W  ILN I  LS+++NAF++AFTSD IP+ VY Y+++      + GY+  +L+    +   E             CRYRD+R   G     ++T  YW +LA ++ F+I+ EH+VF V + +  LIPDVP  ++  ++R+ ++ ++ L
Sbjct:   37 DGSRRIDFVLSYTED---TGKDAEKKAERRRE---FELNLQKSGLELETEDKKESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLKADDLKDDSENILSHVLKLFKLPQ----EVMYPEPDYFTAPFRKDKQELFRTEEREK-FFTPSTRNRIVYYILSRCHYGEEEGKKKFGIKRLLTNGSYLDAYPLHD------CQYWKKTDERNCERYTLYTHWAKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMDDSISSKEICDPNIGGQIIMCPLCD--KRCEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYESKCTEKKKNPVTQEMEPYLPATSKAARFCFSGATVLFWIALIIASIIAIIVYRLWVYAAFASIMDNNLALKPVSNLLTPQLATSVTASVLNFVTIMILNFLYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPADYSYLFGKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKR-RKARNHPQNLYSR------WEHDGDLQTFGGLGLFNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPMSGYIGSSLSVFNVSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQYWHILAAKMAFIIIMEHVVFLVKFFVAWLIPDVPSEVKARVKREKFLTQKIL 837
[Close]
BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO5 (anoctamin 5 [Source:NCBI gene;Acc:100489787])

HSP 1 Score: 504.982 bits (1299), Expect = 1.779e-164
Identity = 329/827 (39.78%), Postives = 473/827 (57.19%), Query Frame = 2 
Query:  338 DGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXK-MMINFIKIHIPFNIMCIYAEALNFRVPLQIG--PPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQT-KGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWN-RRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTN--NTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKP--RPEYVALATEKRVNPVTGIEEPYFPVNLRMKRM-LTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKA------LIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFG-LRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGL--FDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----FLLDGYVNFTLAWAPNNSLSE------------PCRYRDFRDVNG-----KLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            DG RRID+V+ + +D      D E++         F   L K GL  E E ++  +     F+KIH P+ ++  YAE LN ++PL+       + +    VLK F +P     E+ Y    + TA F+ D+ E +     E  FF+ + R+++   IL+   YG +  K + GI R++    Y  AYPLH+           K D  N  R  L+ +WAK+++FYK QP++ IR+YYGEKI IYFAWLG YT  LF A++VG F F+YG +TM     SKEICD N      MCPLC+  K C +W L+  C  SQ +++FD+  T+FF+IFM +W   FLE WKR+ A L Y WD VD+EEE ++   RPEY +  TEK+ NPVT   EPY P   +  R   +G   +  + + +  II II   ++       + DN L            +  SV+A+++N + IM L  +YE++A  +T  E+ RT  E+E+ LT+K++LF+FVN+YSS FY+AFFKG+F GYP  YS  FG  RNE+C    CL EL  Q+ I+M G QI  NIQE F+P    W  R +K  N+   L  +      W  D  L  + GL  F+EYLEM+VQFGFIT+FVA+FPLAP  AL+NN LEIR+D+ KL    +RPVA +A  +G W  ILN I  LS+++NAF++AFTSD IP+ VY Y+++      + GY+  +L+    +   E             CRYRD+R   G     ++T  YW +LA ++ F+I+ EH+VF V + +  LIPDVP  ++  ++R+ ++ ++ L
Sbjct:   37 DGSRRIDFVLSYTED---TGKDAEKKAERRRE---FELNLQKSGLELETEDKKESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLKADDLKDDSENILSHVLKLFKLPQ----EVMYPEPDYFTAPFRKDKQELFRTEEREK-FFTPSTRNRIVYYILSRCHYGEEEGKKKFGIKRLLTNGSYLDAYPLHD------CQYWKKTDERNCERYTLYTHWAKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMDDSISSKEICDPNIGGQIIMCPLCD--KRCEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYESKCTEKKKNPVTQEMEPYLPATSKAARFCFSGATVLFWIALIIASIIAIIVYRLWVYAAFASIMDNNLALKPVSNLLTPQLATSVTASVLNFVTIMILNFLYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPADYSYLFGKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKR-RKARNHPQNLYSR------WEHDGDLQTFGGLGLFNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPMSGYIGSSLSVFNVSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQYWHILAAKMAFIIIMEHVVFLVKFFVAWLIPDVPSEVKARVKREKFLTQKIL 837
[Close]
BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano7 (anoctamin 7 [Source:MGI Symbol;Acc:MGI:3052714])

HSP 1 Score: 743.806 bits (1919), Expect = 0.000e+0
Identity = 388/789 (49.18%), Postives = 554/789 (70.22%), Query Frame = 2 
Query:  353 IDYVIVWEQD-RIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGP-AEVP--TDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLF--DNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAP---NNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            ID+V+VWE+D R   N   ++      +R+ F E L   GL  ++   + E   +++I +  P+ ++C YAE L  ++PLQ  P    ++S  +L++  IPN +   +P +P  + +  FK  +L+ +LG  N+DTFF++T+RHQ+  EILA T YG + KG  GID+++ E ++SAA+PLH+GP + VP  + +LG +    +RQ+LF++WA+W K+ KYQP++++R Y+GEK+A+YFAWLG YT WL PA++VG  VF+ G   + S   ++E+C ++++F MCPLC+    C +W LS  C  +Q   LFDH GTVFFS+FM++WAV  LE WKRKNA L+YRWD  DYE+ +E+PRP++ A A    +NP+TG +EPYFP   R++RML G + +++M  +VI+ ++ VI+YR ++AI +   DN  L + A   AS++ ++VNL+ I+ L  VY  LA  LT+WEMHRT+TEFED  T+KV++F+FVNFY+S  YIAFFKGRF GYPG Y   FG+RNE+C  G CL ELAQ++ +IMVG QIINN+QE+ +PKL   + +F +G     + +G    P  W  DY+LLP EGLF EYLEM++QFGF+TIFVAA PLAP FAL+NNW+EIRLDA K V   RRPVAERAQD+G WF IL  +  L++ISNAFL+AF+SDF+P+  Y ++H   L G++NFTLA AP    ++ +  CRYR FRD +G  +  YW LLAIRL FVIVFEH+VF +  ++D+L+PD+PES++I+++R+ Y+AKQAL
Sbjct:   55 IDFVLVWEEDLRNQENPTKDKTDTHEVWRETFLENLCLAGLKIDQHDVQDEAAAVHYILLRAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLEHVPDTPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKGLFGIDQLLAEGVFSAAFPLHDGPFSAVPESSQVLGLI----QRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLVGCFLVFSDIPTQELCHSSDSFDMCPLCS---DCSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVRRMLAGSVVLLMMVAVVIMCLVSVILYRAVMAIIVSRSDNAFLSAWASRIASLTGSVVNLVFILILSKVYVLLAQVLTRWEMHRTQTEFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGIRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKFSRG-----KKAGTGTHPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILTGLTHLAVISNAFLLAFSSDFLPRVYYSWTHAPDLHGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSIGRVLDLLVPDIPESVEIKVKREYYLAKQAL 831
[Close]
BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano7 (anoctamin 7 [Source:MGI Symbol;Acc:MGI:3052714])

HSP 1 Score: 742.651 bits (1916), Expect = 0.000e+0
Identity = 388/789 (49.18%), Postives = 554/789 (70.22%), Query Frame = 2 
Query:  353 IDYVIVWEQD-RIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGP-AEVP--TDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLF--DNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAP---NNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            ID+V+VWE+D R   N   ++      +R+ F E L   GL  ++   + E   +++I +  P+ ++C YAE L  ++PLQ  P    ++S  +L++  IPN +   +P +P  + +  FK  +L+ +LG  N+DTFF++T+RHQ+  EILA T YG + KG  GID+++ E ++SAA+PLH+GP + VP  + +LG +    +RQ+LF++WA+W K+ KYQP++++R Y+GEK+A+YFAWLG YT WL PA++VG  VF+ G   + S   ++E+C ++++F MCPLC+    C +W LS  C  +Q   LFDH GTVFFS+FM++WAV  LE WKRKNA L+YRWD  DYE+ +E+PRP++ A A    +NP+TG +EPYFP   R++RML G + +++M  +VI+ ++ VI+YR ++AI +   DN  L + A   AS++ ++VNL+ I+ L  VY  LA  LT+WEMHRT+TEFED  T+KV++F+FVNFY+S  YIAFFKGRF GYPG Y   FG+RNE+C  G CL ELAQ++ +IMVG QIINN+QE+ +PKL   + +F +G     + +G    P  W  DY+LLP EGLF EYLEM++QFGF+TIFVAA PLAP FAL+NNW+EIRLDA K V   RRPVAERAQD+G WF IL  +  L++ISNAFL+AF+SDF+P+  Y ++H   L G++NFTLA AP    ++ +  CRYR FRD +G  +  YW LLAIRL FVIVFEH+VF +  ++D+L+PD+PES++I+++R+ Y+AKQAL
Sbjct:   55 IDFVLVWEEDLRNQENPTKDKTDTHEVWRETFLENLCLAGLKIDQHDVQDEAAAVHYILLRAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLEHVPDTPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKGLFGIDQLLAEGVFSAAFPLHDGPFSAVPESSQVLGLI----QRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLVGCFLVFSDIPTQELCHSSDSFDMCPLCS---DCSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVRRMLAGSVVLLMMVAVVIMCLVSVILYRAVMAIIVSRSDNAFLSAWASRIASLTGSVVNLVFILILSKVYVLLAQVLTRWEMHRTQTEFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGIRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKFSRG-----KKAGTGTHPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILTGLTHLAVISNAFLLAFSSDFLPRVYYSWTHAPDLHGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSIGRVLDLLVPDIPESVEIKVKREYYLAKQAL 831
[Close]
BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano4 (anoctamin 4 [Source:MGI Symbol;Acc:MGI:2443344])

HSP 1 Score: 512.686 bits (1319), Expect = 4.518e-167
Identity = 337/871 (38.69%), Postives = 491/871 (56.37%), Query Frame = 2 
Query:  245 NLKKDKNKESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPH---FSERVLKFFLIPNFMKNELPYSP--------------DCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKY-SLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----------FLLDGYVNFTLA---WAPNNSLSEP--------------CRYRDFRDVNGKLTRF-----YWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            NL       SR E        +      Y  DG  RIDY++V+ +       +P+  +R       F   +   GL  E+E       +I F+K+H P+ ++  YAE +N R+P +    + P    F  R+ K   I  F +  LP  P              DC+ TA F   ++  ++ + N+DTFF+   R ++   IL    Y  + K +IG++R++    Y AA+PLHEG       +     + N R +L+E WA W  +YKYQP++ +R Y+GEKI +YFAWLG YT  LFPA+ +G+FVF+YG+ T+    +SKE+C   +   MCP+C  +K C +  LSD C Y+++T+LFD+  TVFF++FM+VWA  FLE WKR+ A ++Y WD +D+EEE+E+ RP++ A  ++K R+NP++G  EPY     +  R++     I  ++  +I  +F I +     +     F   L+R+ + +  + +A  +N  +IM L ++YEK+A  LT  E  RTE+E+E+  T+K++LF+FVN  SS FYIAFF GRF G+PG Y  L    R E+C    CL +L  QM IIMV  Q  NN  E+  P +  W+ R K    +  +   + +    W +DY L P    GLFDEYLEMI+QFGF TIFVAAFPLAP  AL+NN +EIRLDA K V   RRP+A RA+D+G W+ IL  I  LS+I+NAF+IA TSDFIP+ VY Y +             + GYVN +L+    +   + SEP              CRYRD+RD    L  +     +W +LA RL F+IVFEH+VF + +LI  LIPD+P+ L+  MRR+ Y+ ++ +
Sbjct:   48 NLTSTSEDTSRLEAGGETVRERNKSNGLYFRDGKCRIDYILVYRKS------NPQTEKREV-----FERNIRAEGLQMEKESSLINSDII-FVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDK--QISRF-RRWLPKKPMRLDKETLPDLEENDCY-TAPFSQQRIHHFIIH-NKDTFFNNATRSRIVHHILQRIKY-EEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIKTHGAV-NHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHCQVSKEVCQATDII-MCPVC--DKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGTE---RKINFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLAPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 893
[Close]
BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano4 (anoctamin 4 [Source:MGI Symbol;Acc:MGI:2443344])

HSP 1 Score: 512.686 bits (1319), Expect = 4.518e-167
Identity = 337/871 (38.69%), Postives = 491/871 (56.37%), Query Frame = 2 
Query:  245 NLKKDKNKESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPH---FSERVLKFFLIPNFMKNELPYSP--------------DCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKY-SLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----------FLLDGYVNFTLA---WAPNNSLSEP--------------CRYRDFRDVNGKLTRF-----YWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            NL       SR E        +      Y  DG  RIDY++V+ +       +P+  +R       F   +   GL  E+E       +I F+K+H P+ ++  YAE +N R+P +    + P    F  R+ K   I  F +  LP  P              DC+ TA F   ++  ++ + N+DTFF+   R ++   IL    Y  + K +IG++R++    Y AA+PLHEG       +     + N R +L+E WA W  +YKYQP++ +R Y+GEKI +YFAWLG YT  LFPA+ +G+FVF+YG+ T+    +SKE+C   +   MCP+C  +K C +  LSD C Y+++T+LFD+  TVFF++FM+VWA  FLE WKR+ A ++Y WD +D+EEE+E+ RP++ A  ++K R+NP++G  EPY     +  R++     I  ++  +I  +F I +     +     F   L+R+ + +  + +A  +N  +IM L ++YEK+A  LT  E  RTE+E+E+  T+K++LF+FVN  SS FYIAFF GRF G+PG Y  L    R E+C    CL +L  QM IIMV  Q  NN  E+  P +  W+ R K    +  +   + +    W +DY L P    GLFDEYLEMI+QFGF TIFVAAFPLAP  AL+NN +EIRLDA K V   RRP+A RA+D+G W+ IL  I  LS+I+NAF+IA TSDFIP+ VY Y +             + GYVN +L+    +   + SEP              CRYRD+RD    L  +     +W +LA RL F+IVFEH+VF + +LI  LIPD+P+ L+  MRR+ Y+ ++ +
Sbjct:   48 NLTSTSEDTSRLEAGGETVRERNKSNGLYFRDGKCRIDYILVYRKS------NPQTEKREV-----FERNIRAEGLQMEKESSLINSDII-FVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDK--QISRF-RRWLPKKPMRLDKETLPDLEENDCY-TAPFSQQRIHHFIIH-NKDTFFNNATRSRIVHHILQRIKY-EEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIKTHGAV-NHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHCQVSKEVCQATDII-MCPVC--DKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGTE---RKINFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLAPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 893
[Close]
BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano4 (anoctamin 4 [Source:MGI Symbol;Acc:MGI:2443344])

HSP 1 Score: 512.686 bits (1319), Expect = 1.446e-166
Identity = 337/871 (38.69%), Postives = 491/871 (56.37%), Query Frame = 2 
Query:  245 NLKKDKNKESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPH---FSERVLKFFLIPNFMKNELPYSP--------------DCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKY-SLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----------FLLDGYVNFTLA---WAPNNSLSEP--------------CRYRDFRDVNGKLTRF-----YWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            NL       SR E        +      Y  DG  RIDY++V+ +       +P+  +R       F   +   GL  E+E       +I F+K+H P+ ++  YAE +N R+P +    + P    F  R+ K   I  F +  LP  P              DC+ TA F   ++  ++ + N+DTFF+   R ++   IL    Y  + K +IG++R++    Y AA+PLHEG       +     + N R +L+E WA W  +YKYQP++ +R Y+GEKI +YFAWLG YT  LFPA+ +G+FVF+YG+ T+    +SKE+C   +   MCP+C  +K C +  LSD C Y+++T+LFD+  TVFF++FM+VWA  FLE WKR+ A ++Y WD +D+EEE+E+ RP++ A  ++K R+NP++G  EPY     +  R++     I  ++  +I  +F I +     +     F   L+R+ + +  + +A  +N  +IM L ++YEK+A  LT  E  RTE+E+E+  T+K++LF+FVN  SS FYIAFF GRF G+PG Y  L    R E+C    CL +L  QM IIMV  Q  NN  E+  P +  W+ R K    +  +   + +    W +DY L P    GLFDEYLEMI+QFGF TIFVAAFPLAP  AL+NN +EIRLDA K V   RRP+A RA+D+G W+ IL  I  LS+I+NAF+IA TSDFIP+ VY Y +             + GYVN +L+    +   + SEP              CRYRD+RD    L  +     +W +LA RL F+IVFEH+VF + +LI  LIPD+P+ L+  MRR+ Y+ ++ +
Sbjct:   83 NLTSTSEDTSRLEAGGETVRERNKSNGLYFRDGKCRIDYILVYRKS------NPQTEKREV-----FERNIRAEGLQMEKESSLINSDII-FVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDK--QISRF-RRWLPKKPMRLDKETLPDLEENDCY-TAPFSQQRIHHFIIH-NKDTFFNNATRSRIVHHILQRIKY-EEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIKTHGAV-NHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHCQVSKEVCQATDII-MCPVC--DKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGTE---RKINFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLAPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 928
[Close]
BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q14AT5|ANO7_MOUSE (Anoctamin-7 OS=Mus musculus OX=10090 GN=Ano7 PE=1 SV=2)

HSP 1 Score: 743.806 bits (1919), Expect = 0.000e+0
Identity = 388/789 (49.18%), Postives = 554/789 (70.22%), Query Frame = 2 
Query:  353 IDYVIVWEQD-RIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGP-AEVP--TDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLF--DNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAP---NNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            ID+V+VWE+D R   N   ++      +R+ F E L   GL  ++   + E   +++I +  P+ ++C YAE L  ++PLQ  P    ++S  +L++  IPN +   +P +P  + +  FK  +L+ +LG  N+DTFF++T+RHQ+  EILA T YG + KG  GID+++ E ++SAA+PLH+GP + VP  + +LG +    +RQ+LF++WA+W K+ KYQP++++R Y+GEK+A+YFAWLG YT WL PA++VG  VF+ G   + S   ++E+C ++++F MCPLC+    C +W LS  C  +Q   LFDH GTVFFS+FM++WAV  LE WKRKNA L+YRWD  DYE+ +E+PRP++ A A    +NP+TG +EPYFP   R++RML G + +++M  +VI+ ++ VI+YR ++AI +   DN  L + A   AS++ ++VNL+ I+ L  VY  LA  LT+WEMHRT+TEFED  T+KV++F+FVNFY+S  YIAFFKGRF GYPG Y   FG+RNE+C  G CL ELAQ++ +IMVG QIINN+QE+ +PKL   + +F +G     + +G    P  W  DY+LLP EGLF EYLEM++QFGF+TIFVAA PLAP FAL+NNW+EIRLDA K V   RRPVAERAQD+G WF IL  +  L++ISNAFL+AF+SDF+P+  Y ++H   L G++NFTLA AP    ++ +  CRYR FRD +G  +  YW LLAIRL FVIVFEH+VF +  ++D+L+PD+PES++I+++R+ Y+AKQAL
Sbjct:   55 IDFVLVWEEDLRNQENPTKDKTDTHEVWRETFLENLCLAGLKIDQHDVQDEAAAVHYILLRAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLEHVPDTPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKGLFGIDQLLAEGVFSAAFPLHDGPFSAVPESSQVLGLI----QRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLVGCFLVFSDIPTQELCHSSDSFDMCPLCS---DCSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVRRMLAGSVVLLMMVAVVIMCLVSVILYRAVMAIIVSRSDNAFLSAWASRIASLTGSVVNLVFILILSKVYVLLAQVLTRWEMHRTQTEFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGIRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKFSRG-----KKAGTGTHPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILTGLTHLAVISNAFLLAFSSDFLPRVYYSWTHAPDLHGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSIGRVLDLLVPDIPESVEIKVKREYYLAKQAL 831
[Close]
BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q6IFT6|ANO7_RAT (Anoctamin-7 OS=Rattus norvegicus OX=10116 GN=Ano7 PE=2 SV=1)

HSP 1 Score: 729.169 bits (1881), Expect = 0.000e+0
Identity = 383/788 (48.60%), Postives = 546/788 (69.29%), Query Frame = 2 
Query:  353 IDYVIVWEQD-RIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLF--DNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAP---NNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLN 2698
            ID+V+VWE+D R   N   ++      +R+ F E L   GL  ++   + E   +++I +  P+ ++C YAE L  ++PLQ  P    ++S  +L++  IPN +   +P +P  + +  FK  +L+ +LG  N+DTFF++T+RHQ+  EILA T YG Q KG  GID+++ E ++SAA+PLH+GP  V  +    + L  +RQ+LF++WA+W K+ KYQP++++R Y+GEK+A+YFAWLG YT WL PA++VG  VF+ G   + S   ++E+C +++TF MCPLC+    C +W LS  C  +Q   LFDH GTVFFS+FM++WAV  LE WKRKNA L+YRWD  DYE+ +E+PRP++ A A    +NP+TG +EPYFP   R++RML G + +++M  +VI+ ++ +I+YR ++AI +   +N  L + A   AS++ ++VNL+ I+ L  VY  LA  LT+WEMHRT+T FED  T+KV++F+FVNFY+S  YIAFFKGRF GYPG Y   FG+RNE+C  G CL ELAQ++ +IMVG QIINN+QE+ +PKL   + +    L +  + +G    P  W  DY+LLP EGLF EYLEM++QFGF+TIFVAA PLAP FAL+NNW+EIRLDA K V   RRPVAERAQD+G WF IL  +  L++ISNAFL+AF+SDF+P+  Y ++    L G++NFTLA AP    ++ +  CRYR FRD +G  +  YW LLAIRL FVIVFEH+VF     +D+L+PD+PES++I+++R+ Y+AKQAL +
Sbjct:   55 IDFVLVWEEDLRSRENPTQDKTDTHEIWRETFLENLRVAGLKIDQRDVQDEAAAVHYILLSAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLENVPDTPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYGHQKKGLFGIDQLLAEGVFSAAFPLHDGPFSVVPESSQVLGL-TQRQVLFKHWARWGKWRKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLAGCFLVFSDVPTQELCHSSDTFDMCPLCS---DCSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVRRMLAGSVVLLMMVAVVIMCLVSIILYRAVMAIIVSKSNNAFLSAWASRIASLTGSVVNLVFILILSKVYVILAQVLTRWEMHRTQTAFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGVRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQK----LCSRRKKAGMGANPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRVYYSWTRAPDLRGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSTGRFLDLLVPDIPESVEIKVKREYYLAKQALAD 834
[Close]
BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q6IWH7|ANO7_HUMAN (Anoctamin-7 OS=Homo sapiens OX=9606 GN=ANO7 PE=1 SV=2)

HSP 1 Score: 728.013 bits (1878), Expect = 0.000e+0
Identity = 381/806 (47.27%), Postives = 551/806 (68.36%), Query Frame = 2 
Query:  347 RRIDYVIVWEQD----RIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLF--DNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNN---SLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL--------LNMTKNE 2713
            R  D+V+VWE+D    R   +   +R      +R+ F + L   GL  +++  +     +++  +   + ++C YAE L  ++PLQ  P    ++S  +L +  IPN +   +P  P  + +  F+ ++L ++LG  N+DTFF++T+RHQ+  EILA T YG + K  +GI +++ E + SAA+PLH+GP + P +      L N+RQ+LF++WA+W K+ KYQP++++R Y+GEK+A+YFAWLG YT WL PA++VG  VF+ G   + S   ++E+C + ++F+MCPLC     C +W LS  C  +Q   LFDH GTVFFS+FM++WAV  LE WKRK+A L+YRWD  DYE+ +E+PRP++ A A     NP+TG +EPYFP   R +RML G + IVVM  +V++ ++ +I+YR ++AI +    N LL + A   AS++ ++VNL+ I+ L  +Y  LA+ LT+WEMHRT+T+FED  T+KV++F+FVNFYSS  YIAFFKGRF GYPG Y   FG+RNE+C+ G CL ELAQ++ +IMVG Q+INN+QE+ +PKL  W+ +F+         +        W +DY+L+P EGLFDEYLEM++QFGF+TIFVAA PLAP FAL+NNW+EIRLDA K V   RRPVAERAQD+G WF IL  +  L++ISNAFL+AF+SDF+P+  Y+++    L G++NFTLA AP++   + +  CRYR FRD +G  ++ YW LLAIRL FVIVFEH+VF V  L+D+L+PD+PES++I+++R+ Y+AKQAL         N TK+E
Sbjct:  108 RIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQAPRL-NQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC---LDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEVLFGTNGTKDE 909
[Close]
BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|A6QLE6|ANO4_BOVIN (Anoctamin-4 OS=Bos taurus OX=9913 GN=ANO4 PE=2 SV=1)

HSP 1 Score: 512.686 bits (1319), Expect = 3.911e-166
Identity = 340/873 (38.95%), Postives = 494/873 (56.59%), Query Frame = 2 
Query:  245 NLKKDKNKESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPH---FSERVLKFFLIPNFMKNELPYSP--------------DCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKY-SLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSG--KDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----------FLLDGYVNFTLA---WAPNNSLSEP--------------CRYRDFRDVNGKLTRF-----YWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            NL    +  SR E        K      Y  DG  RIDY++V+ +       +P+  +R       F   +   GL  E+E       +I F+K+H P+ ++  YAE +N R+P +    + P    F  R+ K   I  F +  LP  P              DC+ TA F   ++  ++ + N+DTFF+   R ++   IL    Y  + K +IG++R++    Y AA+PLHEG       +     + N R +L+E WA W  +YKYQP++ +R Y+GEKI +YFAWLG YT  LFPA+ +G+FVF+YG++T+    +SKE+C   +   MCP+C  +K C +  LSD C Y+++T+LFD+  TVFF++FM+VWA  FLE WKR+ A ++Y WD +D+EEE+E+ RP++ A  ++K R+NP++G  EPY     +  R++     I  ++  +I  +F I +     +     F   L+R+ + +  + +A  +N  +IM L ++YEK+A  LT  E  RTE+E+E+  T+K++LF+FVN  SS FYIAFF GRF G+PG Y  L    R E+C    CL +L  QM IIMV  Q  NN  E+  P +  W+ R K     + Q  G  + +    W +DY L P    GLFDEYLEMI+QFGF TIFVAAFPLAP  AL+NN +EIRLDA K V   RRP+A RA+D+G W+ IL  I  LS+I+NAF+IA TSDFIP+ VY Y +             + GYVN +L+    +   + SEP              CRYRD+RD    L  +     +W +LA RL F+IVFEH+VF + +LI  LIPD+P+ L+  MRR+ Y+ ++ +
Sbjct:   48 NLTSTSDDASRLEAGGETVPEKNKLNGLYFRDGKCRIDYILVYRKS------NPQMEKREV-----FERNIRAEGLQMEKESSLINSDII-FVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDK--QISRF-RRWLPKKPMRLDKETLPDLEENDCY-TAPFSQQRIHHFIIH-NKDTFFNNATRSRIVHHILQRIKY-EEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAV-NHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVITLDHCQVSKEVCQATDII-MCPVC--DKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFADKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRK-----VRQEHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 893
[Close]
BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q8C5H1|ANO4_MOUSE (Anoctamin-4 OS=Mus musculus OX=10090 GN=Ano4 PE=1 SV=2)

HSP 1 Score: 512.686 bits (1319), Expect = 1.011e-165
Identity = 337/871 (38.69%), Postives = 491/871 (56.37%), Query Frame = 2 
Query:  245 NLKKDKNKESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPH---FSERVLKFFLIPNFMKNELPYSP--------------DCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXX--XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKY-SLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----------FLLDGYVNFTLA---WAPNNSLSEP--------------CRYRDFRDVNGKLTRF-----YWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            NL       SR E        +      Y  DG  RIDY++V+ +       +P+  +R       F   +   GL  E+E       +I F+K+H P+ ++  YAE +N R+P +    + P    F  R+ K   I  F +  LP  P              DC+ TA F   ++  ++ + N+DTFF+   R ++   IL    Y  + K +IG++R++    Y AA+PLHEG       +     + N R +L+E WA W  +YKYQP++ +R Y+GEKI +YFAWLG YT  LFPA+ +G+FVF+YG+ T+    +SKE+C   +   MCP+C  +K C +  LSD C Y+++T+LFD+  TVFF++FM+VWA  FLE WKR+ A ++Y WD +D+EEE+E+ RP++ A  ++K R+NP++G  EPY     +  R++     I  ++  +I  +F I +     +     F   L+R+ + +  + +A  +N  +IM L ++YEK+A  LT  E  RTE+E+E+  T+K++LF+FVN  SS FYIAFF GRF G+PG Y  L    R E+C    CL +L  QM IIMV  Q  NN  E+  P +  W+ R K    +  +   + +    W +DY L P    GLFDEYLEMI+QFGF TIFVAAFPLAP  AL+NN +EIRLDA K V   RRP+A RA+D+G W+ IL  I  LS+I+NAF+IA TSDFIP+ VY Y +             + GYVN +L+    +   + SEP              CRYRD+RD    L  +     +W +LA RL F+IVFEH+VF + +LI  LIPD+P+ L+  MRR+ Y+ ++ +
Sbjct:   83 NLTSTSEDTSRLEAGGETVRERNKSNGLYFRDGKCRIDYILVYRKS------NPQTEKREV-----FERNIRAEGLQMEKESSLINSDII-FVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDK--QISRF-RRWLPKKPMRLDKETLPDLEENDCY-TAPFSQQRIHHFIIH-NKDTFFNNATRSRIVHHILQRIKY-EEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIKTHGAV-NHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHCQVSKEVCQATDII-MCPVC--DKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGTE---RKINFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLAPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 928
[Close]
BLAST of Anoctamin vs. TrEMBL
Match: A0A267H1A6 (Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021551g3 PE=3 SV=1)

HSP 1 Score: 926.391 bits (2393), Expect = 0.000e+0
Identity = 500/817 (61.20%), Postives = 636/817 (77.85%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWEQDRIAINVDPEX--XXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMT--KNEMGSLKRGESLLVKADSKA 2767
            Y  DG+RR+D+VIVWE+D    + DPE    +R   YR+RF   L K+G+  EEE   SEK  I+FIK+ +P+++MC YAE L  R PLQ       ++S +VLK   IPN M+  +P  P  + T  F+  +L K+LG  ++DT+FS+TQRHQVA EILAT VYG++ + E+GIDR+++EE+YS A+PLHEGP E+P D   + DL N RQIL  YWAKW  +YKYQP+++IREYYGEKI +YFAWLGLYTAWL PAS+VGI VF+YG  T K+     E+CD+N T+KMCPLC+   GC+YW LSDIC + +++YLFDHPGTVF+S+F++ WAV FLENWKRKNA L++ WD +D+EE++E+PRPEY AL +    NPVTG  EP+FP +LR+ R++TG+ CI++M +IV+IFII VIIYR+LIAIPLF NPLLRS+A   AS SAAIVNLILIMSLG VYEKLAYKLTQWEMHRT+TEFED L +KV++F+FVNFYSSIFYIAFFKG+F GYPG+Y  FFGLRNE+C NG CL ELAQQ+A+IM+G QIINN QE+FLPKL TW HRF KGLN       ++ E      DY+L+PYEGLF+EYLEM++QFGFITIFVAAFPLAPFFAL+NNWLEIRLDASKLV  TRRPV+ERAQD+G WF +L++IV+LS+ISNAFLIAFTS+F+PK++YKY  +  L GY NFTLAW+P NS ++PCRY+ FR  +G  T FYW+LLA+RL FVIVFEH+VF ++ ++DILIPDVPE LQ++++R+ Y+AKQAL++    +++   L+     LV  DS A
Sbjct:   67 YFADGVRRVDFVIVWEEDLQRADDDPEDPWEQRKAVYRRRFEGNLRKVGVQMEEETSTSEKKKIHFIKLFVPWDVMCYYAEDLCLRAPLQAHSHPADNWSGKVLKSLHIPNVMEQRVPNQPLDYYTCPFRKSKLSKFLGSDDQDTYFSSTQRHQVAYEILATQVYGKRKRAEVGIDRLLEEEVYSGAFPLHEGPYELPKDYQPE-DL-NARQILNAYWAKWGLWYKYQPLDHIREYYGEKIGLYFAWLGLYTAWLLPASIVGIIVFLYGCFTFKANVPGNEVCDSNMTYKMCPLCDEAIGCKYWYLSDICMFMRISYLFDHPGTVFYSVFVAFWAVTFLENWKRKNASLAHHWDVMDFEEDEERPRPEYSALCSSYERNPVTGNLEPHFPNSLRIPRIITGITCIIIMMVIVVIFIIAVIIYRVLIAIPLFQNPLLRSQASTVASGSAAIVNLILIMSLGKVYEKLAYKLTQWEMHRTQTEFEDQLILKVFIFQFVNFYSSIFYIAFFKGKFTGYPGRYIKFFGLRNEECDNGGCLIELAQQLAVIMIGKQIINNCQEVFLPKLFTWIHRFTKGLN---WSRSQEAEASRCQADYQLIPYEGLFEEYLEMVLQFGFITIFVAAFPLAPFFALLNNWLEIRLDASKLVCETRRPVSERAQDIGVWFTLLDVIVQLSVISNAFLIAFTSEFLPKELYKYQFDSELHGYTNFTLAWSPANSTAQPCRYKAFRGEDGHYTMFYWKLLAVRLAFVIVFEHVVFFISRMLDILIPDVPEVLQVKIKREQYLAKQALMDAETLQSQRLQLQTDAEALVGGDSVA 878
[Close]
BLAST of Anoctamin vs. TrEMBL
Match: A0A267FA31 (Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006611g1 PE=3 SV=1)

HSP 1 Score: 926.006 bits (2392), Expect = 0.000e+0
Identity = 500/817 (61.20%), Postives = 636/817 (77.85%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWEQDRIAINVDPEX--XXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMT--KNEMGSLKRGESLLVKADSKA 2767
            Y  DG+RR+D+VIVWE+D    + DPE    +R   YR+RF   L K+G+  EEE   SEK  I+FIK+ +P+++MC YAE L  R PLQ       ++S +VLK   IPN M+  +P  P  + T  F+  +L K+LG  ++DT+FS+TQRHQVA EILAT VYG++ + E+GIDR+++EE+YS A+PLHEGP E+P D   + DL N RQIL  YWAKW  +YKYQP+++IREYYGEKI +YFAWLGLYTAWL PAS+VGI VF+YG  T K+     E+CD+N T+KMCPLC+   GC+YW LSDIC + +++YLFDHPGTVF+S+F++ WAV FLENWKRKNA L++ WD +D+EE++E+PRPEY AL +    NPVTG  EP+FP +LR+ R++TG+ CI++M +IV+IFII VIIYR+LIAIPLF NPLLRS+A   AS SAAIVNLILIMSLG VYEKLAYKLTQWEMHRT+TEFED L +KV++F+FVNFYSSIFYIAFFKG+F GYPG+Y  FFGLRNE+C NG CL ELAQQ+A+IM+G QIINN QE+FLPKL TW HRF KGLN       ++ E      DY+L+PYEGLF+EYLEM++QFGFITIFVAAFPLAPFFAL+NNWLEIRLDASKLV  TRRPV+ERAQD+G WF +L++IV+LS+ISNAFLIAFTS+F+PK++YKY  +  L GY NFTLAW+P NS ++PCRY+ FR  +G  T FYW+LLA+RL FVIVFEH+VF ++ ++DILIPDVPE LQ++++R+ Y+AKQAL++    +++   L+     LV  DS A
Sbjct:   67 YFADGVRRVDFVIVWEEDLQRADDDPEDPWEQRKAVYRRRFEGNLRKVGVQMEEETSTSEKKKIHFIKLFVPWDVMCYYAEDLCLRAPLQAHSHPADNWSGKVLKSLHIPNAMEQRVPNQPLDYYTCPFRKSKLSKFLGSDDQDTYFSSTQRHQVAYEILATQVYGKRKRAEVGIDRLLEEEVYSGAFPLHEGPYELPKDYQPE-DL-NARQILNAYWAKWGLWYKYQPLDHIREYYGEKIGLYFAWLGLYTAWLLPASIVGIIVFLYGCFTFKANVPGNEVCDSNMTYKMCPLCDEAIGCKYWYLSDICMFMRISYLFDHPGTVFYSVFVAFWAVTFLENWKRKNASLAHHWDVMDFEEDEERPRPEYSALCSSYERNPVTGNLEPHFPNSLRIPRIITGITCIIIMMVIVVIFIIAVIIYRVLIAIPLFQNPLLRSQASTVASGSAAIVNLILIMSLGKVYEKLAYKLTQWEMHRTQTEFEDQLILKVFIFQFVNFYSSIFYIAFFKGKFTGYPGRYIKFFGLRNEECDNGGCLIELAQQLAVIMIGKQIINNCQEVFLPKLFTWIHRFTKGLN---WSRSQEAEASRCQADYQLIPYEGLFEEYLEMVLQFGFITIFVAAFPLAPFFALLNNWLEIRLDASKLVCETRRPVSERAQDIGVWFTLLDVIVQLSVISNAFLIAFTSEFLPKELYKYQFDSELHGYTNFTLAWSPANSTAQPCRYKAFRGEDGHYTMFYWKLLAVRLAFVIVFEHVVFFISRMLDILIPDVPEVLQVKIKREQYLAKQALMDAETLQSQRLQLQTDAEALVGGDSVA 878
[Close]
BLAST of Anoctamin vs. TrEMBL
Match: A0A267GKF1 (Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021551g2 PE=3 SV=1)

HSP 1 Score: 925.62 bits (2391), Expect = 0.000e+0
Identity = 500/817 (61.20%), Postives = 636/817 (77.85%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWEQDRIAINVDPEX--XXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMT--KNEMGSLKRGESLLVKADSKA 2767
            Y  DG+RR+D+VIVWE+D    + DPE    +R   YR+RF   L K+G+  EEE   SEK  I+FIK+ +P+++MC YAE L  R PLQ       ++S +VLK   IPN M+  +P  P  + T  F+  +L K+LG  ++DT+FS+TQRHQVA EILAT VYG++ + E+GIDR+++EE+YS A+PLHEGP E+P D   + DL N RQIL  YWAKW  +YKYQP+++IREYYGEKI +YFAWLGLYTAWL PAS+VGI VF+YG  T K+     E+C++N T+KMCPLC+   GC+YW LSDIC + +++YLFDHPGTVF+S+F++ WAV FLENWKRKNA L++ WD +D+EE++E+PRPEY AL +    NPVTG  EP+FP +LR+ R++TG+ CI++M +IV+IFII VIIYR+LIAIPLF NPLLRS+A   AS SAAIVNLILIMSLG VYEKLAYKLTQWEMHRT+TEFED L +KV++F+FVNFYSSIFYIAFFKG+F GYPGKY  FFGLRNE+C NG CL ELAQQ+A+IM+G QIINN QE+FLPKL TW HRF KGLN       ++ E      DY+L+PYEGLF+EYLEM++QFGFITIFVAAFPLAPFFAL+NNWLEIRLDASKLV  TRRPV+ERAQD+G WF +L++IV+LS+ISNAFLIAFTS+F+PK++YKY  +  L GY NFTLAW+P NS ++PCRY+ FR  +G  T FYW+LLA+RL FVIVFEH+VF ++ ++DILIPDVPE LQ++++R+ Y+AKQAL++    +++   L+     LV  DS A
Sbjct:   67 YFADGVRRVDFVIVWEEDLQRADDDPEDPWEQRKAVYRRRFEGNLRKVGVQMEEETSTSEKKKIHFIKLFVPWDVMCYYAEDLCLRAPLQAHSHPADNWSGKVLKSLHIPNVMEQRVPNQPLDYYTCPFRKSKLSKFLGSDDQDTYFSSTQRHQVAYEILATQVYGKRKRAEVGIDRLLEEEVYSGAFPLHEGPYELPKDYQPE-DL-NARQILNAYWAKWGLWYKYQPLDHIREYYGEKIGLYFAWLGLYTAWLLPASIVGIIVFLYGCFTFKANVPGNEVCESNMTYKMCPLCDEAIGCKYWYLSDICMFMRISYLFDHPGTVFYSVFVAFWAVTFLENWKRKNASLAHHWDVMDFEEDEERPRPEYSALCSSYERNPVTGNLEPHFPNSLRIPRIITGITCIIIMMVIVVIFIIAVIIYRVLIAIPLFQNPLLRSQASTVASGSAAIVNLILIMSLGKVYEKLAYKLTQWEMHRTQTEFEDQLILKVFIFQFVNFYSSIFYIAFFKGKFTGYPGKYIKFFGLRNEECDNGGCLIELAQQLAVIMIGKQIINNCQEVFLPKLFTWIHRFTKGLN---WSRSQEAEASRCQADYQLIPYEGLFEEYLEMVLQFGFITIFVAAFPLAPFFALLNNWLEIRLDASKLVCETRRPVSERAQDIGVWFTLLDVIVQLSVISNAFLIAFTSEFLPKELYKYQFDSELHGYTNFTLAWSPANSTAQPCRYKAFRGEDGHYTMFYWKLLAVRLAFVIVFEHVVFFISRMLDILIPDVPEVLQVKIKREQYLAKQALMDAETLQSQRLQLQTDAEALVGGDSVA 878
[Close]
BLAST of Anoctamin vs. TrEMBL
Match: A0A267F3V4 (Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023540g2 PE=3 SV=1)

HSP 1 Score: 888.256 bits (2294), Expect = 0.000e+0
Identity = 446/728 (61.26%), Postives = 581/728 (79.81%), Query Frame = 2 
Query:  512 INFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSE-DYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            ++F+K+ +P+++MC YAE L  R PLQ     T ++S +VL+   IPN M   +P  P  + T  F+  +L K+LG  N D +F+ TQRHQVA EILAT  YG + K EIGIDR++++  Y+ A+PLHEGP E+P     + +  N RQIL  YWA W  +YKYQP+++IREYYGEKI +YFAWLGLYTAWL PAS+VGI VF+YG  T +S   ++E C+++  +KMCPLC+   GC YW LSDIC Y +M+YLFDHPGTVF+S+F++ WAV FLENWKRKNA L++ WD +D++E++E+PRPEY AL+   + NPVTG  EP+FP   R+ R++TGVMCI++M ++V+IFII VIIYR+LIAIPLF NPLLRS+A   AS SAA VNL+LIMSLG VYEKLAYKLTQWEMHRT+T+FE+ L +KV++F+FVNFYSSI YIAFFKG+F GYPG+Y +FFGLRNE+CS+G CL ELAQQ+A+IMVG QIINN QE+F+PKL+TW HRF KG++     + +D  P    E DY+L+PYEGLF+EYLEM++QFGFITIFVAAFPLAPFFAL+NNWLEIRLDASKLV  TRRPV+ERAQD+G WFI+L++IV+LS+ISNAFLIAFTS+F+P+Q+Y Y ++  L GY NF+LAW+P+N+ ++PCRY+ FRD +G  + FYW+LLA+RL FVI FEH+VF ++ ++DILIPDVP+SLQ++++R+ Y+AKQAL
Sbjct:    1 MHFLKLFLPWDVMCYYAEDLCLRAPLQARHNPTENWSGQVLRHLRIPNVMDQVVPNQPPDYYTCPFRKSKLNKFLGSENRDAYFTATQRHQVAYEILATRAYGLRRKAEIGIDRLLEDGTYAGAFPLHEGPYELPKTF--QPEQLNPRQILHAYWAAWGTWYKYQPLDHIREYYGEKIGLYFAWLGLYTAWLLPASIVGILVFLYGCFTFQSNVPAREACESDQAYKMCPLCDETIGCNYWYLSDICVYIKMSYLFDHPGTVFYSVFIAFWAVTFLENWKRKNASLAHHWDVMDFQEDEERPRPEYSALSPVYQRNPVTGNLEPHFPNRKRIPRIVTGVMCIIIMMVLVVIFIIAVIIYRVLIAIPLFQNPLLRSQATTVASGSAACVNLVLIMSLGKVYEKLAYKLTQWEMHRTQTDFENQLILKVFIFQFVNFYSSILYIAFFKGKFTGYPGRYGMFFGLRNEECSSGGCLIELAQQLAVIMVGKQIINNCQEVFVPKLLTWMHRFSKGIS----WARRDERPMTRCEADYQLIPYEGLFEEYLEMVLQFGFITIFVAAFPLAPFFALLNNWLEIRLDASKLVCETRRPVSERAQDIGVWFILLDVIVQLSVISNAFLIAFTSEFLPRQLYMYQYDSQLRGYTNFSLAWSPSNTTAQPCRYKAFRDADGSHSVFYWKLLAVRLAFVIAFEHVVFFISRMLDILIPDVPQSLQLKIKREQYLAKQAL 722
[Close]
BLAST of Anoctamin vs. TrEMBL
Match: A0A4Z2DG13 (Anoctamin OS=Schistosoma japonicum OX=6182 GN=EWB00_001297 PE=3 SV=1)

HSP 1 Score: 882.863 bits (2280), Expect = 0.000e+0
Identity = 459/822 (55.84%), Postives = 614/822 (74.70%), Query Frame = 2 
Query:  242 INLKKDKNKESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDV-EPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMT 2704
            I      ++E    +P  KT+TK     YY +DG R+IDYV+VW++  I  N+  + R   + YRK F E LLK+G+  E+E  +SE +  +++K+HIP+++MC YAE LN R PL++      ++SE +L    IP+ M   +P  P  + T  FK  +LE++LG+ N + +FS+TQRHQVA +ILAT  YG + K ++GIDR+I EE+Y+AAY +HEGP EV  + L   +  N RQ+L+ YWA+W  +Y+YQP+++IR YYGEKI  YFAWLGLYTAWL PA+ VGIFVF+YG+ T+  Y   KE C+ +    MCP C+ + GCRYWNL ++CFY +M+YLFDHPG+VF++IFM +W V FLE WKRKNA+L++RWD +DYE E+E+PRP+Y A  T+   NP+T + EPYFP   R+ R++TG++C++VM M+V++FII VIIYR LI IPLF N LLR  A I+A++SAAIVNLILIM LG VYE LAYK+TQWEMHRT++EF++ L  KV++F+FVNFYSSIFY+AFFKG+  GYPG Y+ FFGLRNE C NG CL ELAQQ+ +IMVG QII+N QEI LPKL +W+H+++KGLN     S  D+    ++ EDYKL+PYEGLFDEYLEM++QFGFITIFVAAFPLAPFFAL+NNW+EIRLDA KLV  TRRP+AER Q++G WF IL  +V+L++ISNAF+IAF S F+P+ +YK+     L G+ NFTL+WAP N+ S+PCRY+ FRD NG+ + F+WRLLA RL FVIVFEH+ F +A  +D  IPDVP SL+  ++R+ ++AKQALL+++
Sbjct:   11 IKAPMSSDQEKLFSSPQEKTDTK---FGYYFSDGRRKIDYVLVWDEP-INENIVSKVRMINSTYRKTFEENLLKLGVQIEKEDVKSETLKTHYLKLHIPWDLMCHYAECLNLRAPLEVQNTKMKNWSEVILSTVGIPSIMAQNVPNHPPDYYTCPFKKSKLERFLGHDNPEAYFSSTQRHQVAYDILATQAYGNREKAQVGIDRLIQEEVYNAAYAIHEGPYEVNDEDLKHPEKMNPRQVLYWYWARWGCWYRYQPLDHIRSYYGEKIGFYFAWLGLYTAWLLPAAFVGIFVFIYGLATINDYVPVKEACERDTI--MCPTCDIKHGCRYWNLRELCFYLKMSYLFDHPGSVFYAIFMVIWGVTFLEYWKRKNAKLAHRWDVLDYEIEEERPRPQYSAHCTQYAKNPITDVLEPYFPSRARVARIITGLICVMVMVMLVLVFIIAVIIYRFLIKIPLFQNKLLRPNAEIYATLSAAIVNLILIMCLGKVYETLAYKMTQWEMHRTQSEFDNQLIFKVFIFQFVNFYSSIFYVAFFKGQMVGYPGHYTSFFGLRNEACDNGGCLIELAQQLLVIMVGKQIISNCQEILLPKLRSWYHKYRKGLNKRNSTSTSDLSSAHIYIEDYKLIPYEGLFDEYLEMVLQFGFITIFVAAFPLAPFFALLNNWIEIRLDAKKLVCETRRPLAERGQNIGVWFGILEFLVRLAVISNAFIIAFRSSFLPELMYKHEVRSDLVGFTNFTLSWAPPNTTSQPCRYKAFRDNNGEYSMFFWRLLAFRLAFVIVFEHVAFVLANALDFFIPDVPSSLKERIQRERFLAKQALLDIS 826
[Close]
BLAST of Anoctamin vs. Ensembl Cavefish
Match: ano11 (anoctamin-7 [Source:NCBI gene;Acc:103029593])

HSP 1 Score: 778.474 bits (2009), Expect = 0.000e+0
Identity = 427/818 (52.20%), Postives = 580/818 (70.90%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWE----QDRIA-------------------INVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFD--NPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAP---NNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLN 2698
            Y  DG  +IDYV+VWE    + R A                    +   +R+ ++  +R RF + +   GL  E+E   S K  I+++K+  P++++  YAE L  R PLQ  P    + S RVL+   +PN M + +P  P  + T AF+  ++EK+LG  +   +FS TQRH++  EILA TVYG++   E+G  R+++E  + AA+PLHEGP E+P D     D  N+RQIL+ YWA+WSK+YKYQP+++IREY+GEKIA+YFAWLG YTAWL PA++VG FVFV GI+TM S T +KEIC++   + MCPLC   + C+ WN+SDIC  +Q+ YLFDHPGTVFFS+FMS WAV FLE WKRKNA L++ WD +D+ EE+E PRPE+ A+A     NPVTG++EPYFP   R+ RMLTG M IV+M  +V+IF++ VIIYR ++++ +++  + +LR++A   A++S+++VNL LI+ +G VY  LA +LT+WEMHRT+T++ED  T KV++F+FVNFYSS FY+AFFKGRF GYPG Y   FG+RNEDC  G CL ELA+Q+ IIM+G Q+INN+QE  +PK+  W  R KK L ++ +  G  +EP+ W +DY+L+  EGLFDEYLE+++QFGFITIFVAAFPLAP FAL+NNW E+RLDA K V   RRPVAERAQ++G WFIIL  +  +S+I NAFLIAFTSDF+P+ +Y+Y  N  L GYVNFTLA+AP   N S    CRY+ FRD NG  T  YW LLA+RL F+I FEH+VF V  +ID ++PDVPESL+++++R+ Y+AKQAL +
Sbjct:   75 YFRDGQTKIDYVLVWEIKSRRKRRAQGKGRGEAEDEEELQAAQEESRSEKRKAQVARWRDRFIQNIQSAGLLLEKEETSSAKKTIHYLKLSAPWDVLVYYAEELCLRAPLQAQPHPDFNTSARVLQKLWMPNVMADFVPNRPVDYYTCAFRKSKMEKFLGSEDHQNYFSITQRHRIVYEILARTVYGKRKHAEVGAARLLNEGAFKAAFPLHEGPFELP-DYEISPDQLNKRQILYHYWARWSKWYKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAAIVGTFVFVSGIMTMGSNTPAKEICESGGHYLMCPLC---ETCKPWNMSDICPMAQVGYLFDHPGTVFFSVFMSFWAVTFLEYWKRKNATLAHHWDCMDFHEEEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMYETGSSVLRTQAGNIANISSSMVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLFIIMIGKQLINNVQEFVIPKVKAW--RQKKALASVKKAQG-GLEPQRWEQDYELVACEGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWAEVRLDAHKFVCEYRRPVAERAQNIGVWFIILEALSHVSVIVNAFLIAFTSDFLPRLLYRYKFNSDLHGYVNFTLAYAPPSYNYSSHGMCRYKAFRDENGSYTLVYWELLAVRLGFIIAFEHVVFSVLRVIDWMVPDVPESLELKVKRERYLAKQALAD 885
[Close]
BLAST of Anoctamin vs. Ensembl Cavefish
Match: ano11 (anoctamin-7 [Source:NCBI gene;Acc:103029593])

HSP 1 Score: 731.48 bits (1887), Expect = 0.000e+0
Identity = 407/781 (52.11%), Postives = 548/781 (70.17%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWE----QDRIA-------------------INVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFD--NPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAP---NNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEH 2587
            Y  DG  +IDYV+VWE    + R A                    +   +R+ ++  +R RF + +   GL  E+E   S K  I+++K+  P++++  YAE L  R PLQ  P    + S RVL+   +PN M + +P  P  + T AF+  ++EK+LG  +   +FS TQRH++  EILA TVYG++   E+G  R+++E  + AA+PLHEGP E+P D     D  N+RQIL+ YWA+WSK+YKYQP+++IREY+GEKIA+YFAWLG YTAWL PA++VG FVFV GI+TM S T +KEIC++   + MCPLC   + C+ WN+SDIC  +Q+ YLFDHPGTVFFS+FMS WAV FLE WKRKNA L++ WD +D+ EE+E PRPE+ A+A     NPVTG++EPYFP   R+ RMLTG M IV+M  +V+IF++ VIIYR ++++ +++  + +LR++A   A++S+++VNL LI+ +G VY  LA +LT+WEMHRT+T++ED  T KV++F+FVNFYSS FY+AFFKGRF GYPG Y   FG+RNEDC  G CL ELA+Q+ IIM+G Q+INN+QE  +PK+  W  R KK L ++ +  G  +EP+ W +DY+L+  EGLFDEYLE+++QFGFITIFVAAFPLAP FAL+NNW E+RLDA K V   RRPVAERAQ++G WFIIL  +  +S+I NAFLIAFTSDF+P+ +Y+Y  N  L GYVNFTLA+AP   N S    CRY+ FRD NG  T  YW LLA+RL F+I FE 
Sbjct:   75 YFRDGQTKIDYVLVWEIKSRRKRRAQGKGRGEAEDEEELQAAQEESRSEKRKAQVARWRDRFIQNIQSAGLLLEKEETSSAKKTIHYLKLSAPWDVLVYYAEELCLRAPLQAQPHPDFNTSARVLQKLWMPNVMADFVPNRPVDYYTCAFRKSKMEKFLGSEDHQNYFSITQRHRIVYEILARTVYGKRKHAEVGAARLLNEGAFKAAFPLHEGPFELP-DYEISPDQLNKRQILYHYWARWSKWYKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAAIVGTFVFVSGIMTMGSNTPAKEICESGGHYLMCPLC---ETCKPWNMSDICPMAQVGYLFDHPGTVFFSVFMSFWAVTFLEYWKRKNATLAHHWDCMDFHEEEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMYETGSSVLRTQAGNIANISSSMVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLFIIMIGKQLINNVQEFVIPKVKAW--RQKKALASVKKAQG-GLEPQRWEQDYELVACEGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWAEVRLDAHKFVCEYRRPVAERAQNIGVWFIILEALSHVSVIVNAFLIAFTSDFLPRLLYRYKFNSDLHGYVNFTLAYAPPSYNYSSHGMCRYKAFRDENGSYTLVYWELLAVRLGFIIAFEQ 848
[Close]
BLAST of Anoctamin vs. Ensembl Cavefish
Match: si:dkey-83h2.5 (anoctamin-7-like [Source:NCBI gene;Acc:103022406])

HSP 1 Score: 711.835 bits (1836), Expect = 0.000e+0
Identity = 404/833 (48.50%), Postives = 563/833 (67.59%), Query Frame = 2 
Query:  335 NDGIRRIDYVIVWEQDRIAINV-DPEXXXXXXXXXXXFHE----KLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFD--NPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKL--WSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSE--PCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQA----------LLNMTKNEMGSLK-RGESLLVKADSKA 2767
            +DG+ RID+V+VW++    +   +PE +       +++ E    KL   GL  E++     K    ++ +  P+NI+C YAE ++ RVPLQ+      ++SE++L    IPN +  ++P  P  + T  F T +LE++L + N+DTFF TTQRHQ+  EIL+ T YG   +GE+GI R+I E  ++AAYPLHEGP  +P    G   L + RQIL++YWA+W+ + KYQP+ +IREY+GEK+A+YFAWLG YT WL PA++VG F+ ++GI  M +   ++E+C       MCPLC+    C YWNLS IC   ++  LFD+ GTVFFSIFMS+WAV FLE+WKR  A LS+RWD  ++EE +E+PRPE+ A+A     NPVTG EEP+FP   R +R++TG M I++M  +V+IF+I +I+YR +++I ++   N      A   AS++ +++NL++I+ L  VY  LA  LT+WEMHRT+T++ED  T+KV++F+FVNFYSS  YIAFFKGRF GYPG Y   FG+RNEDC    CL ELAQ++ +IMVG Q+INN+QE  LPK+  W++  K+ L+   + +G ++   +  W  DY+LL  EGLF EYLEM++QFGFITIFVAA PLAPFFAL+NNW+EIRLD+ K V   RRPVAERAQD+G WF IL +I  L++ISNAFLIAFTSDF+P+  Y+Y+    L GY++FTL+ APNN       CRYR FRD  G  T  Y+ LLAIRL FVI+FEH+VF +  +ID ++PD+PE ++I+++R+ YMAK+A          LLN T      L+ RG S     D+ +
Sbjct:   42 SDGVTRIDFVLVWDEPVTPLKASEPEDKTSTQATHRKWREEFLSKLQTAGLQQEQKEVVQSKTKTTYVLLSAPWNILCYYAEEISLRVPLQVETNEDSNWSEKILHKLHIPNILAQQVPNPPPDYYTCQFHTKKLERFLDHENKDTFFKTTQRHQILYEILSRTPYGAMKRGEVGIARLITEGAFTAAYPLHEGPYHMPRGPAGPESL-STRQILYQYWARWACWKKYQPLHHIREYFGEKVALYFAWLGFYTGWLLPAAVVGFFLSLFGIWLMVTDVPAQEVCHNGENIVMCPLCDI---CSYWNLSSICTTFRVGLLFDNGGTVFFSIFMSLWAVTFLEHWKRTCAVLSHRWDCSEFEESEERPRPEFAAMAPTTIRNPVTGAEEPHFPETSRFRRIITGNMVIIIMVAVVLIFLIAIILYRSILSIIIYKSHNAFFIFSAGRIASLTGSVLNLVVILLLSKVYTYLAQILTRWEMHRTQTKYEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYYKLFGIRNEDCGASGCLIELAQELLVIMVGKQVINNVQEFVLPKIKAWWN--KRKLHPTQRENGANITENVAPWETDYELLMCEGLFSEYLEMVLQFGFITIFVAACPLAPFFALVNNWVEIRLDSQKFVCEYRRPVAERAQDIGIWFTILQVITYLAVISNAFLIAFTSDFLPRLYYRYTTEGSLRGYMDFTLSVAPNNFTQSHMQCRYRGFRDDKGHHTPEYYNLLAIRLGFVIIFEHVVFLIGRMIDWMVPDIPEEVEIKIKREQYMAKKALAENQSLEEVLLNETPRPNSELRHRGRSAASSRDTDS 868
[Close]
BLAST of Anoctamin vs. Ensembl Cavefish
Match: si:dkey-83h2.5 (anoctamin-7-like [Source:NCBI gene;Acc:103022406])

HSP 1 Score: 669.463 bits (1726), Expect = 0.000e+0
Identity = 375/752 (49.87%), Postives = 505/752 (67.15%), Query Frame = 2 
Query:  443 FHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSE--PCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            F  KL   GL  +E++    K    ++ +  P+NI+C YAE ++ RVPLQ+      ++SE++L    IPN +  ++P  P  + T  F T +LE++L + N+DTFF TTQRHQ+  EIL+ T YG   +GE+GI R+I E  ++AAYPLHEGP  +P    G   L + RQIL++YWA+W+ + KYQP+ +IREY+GEK+A+YFAWLG YT WL PA++VG F+ ++GI  M +   ++E+C       MCPLC+    C YWNLS IC   ++  LFD+ GTVFFSIFMS+WAV FLE+WKR  A LS+RWD  ++EE +E+PRPE+ A+A     NPVTG EEP+FP   R +R++TG M I++M  +V+IF              L    L RS   I    S     +  +  L +  ++  + L   EMHRT+T++ED  T+KV++F+FVNFYSS  YIAFFKGRF GYPG Y   FG+RNEDC    CL ELAQ++ +IMVG Q+INN+QE  LPKL    H  ++   N   ++ ++V P  W  DY+LL  EGLF EYLEM++QFGFITIFVAA PLAPFFAL+NNW+EIRLD+ K V   RRPVAERAQD+G WF IL +I  L++ISNAFLIAFTSDF+P+  Y+Y+    L GY++FTL+ APNN       CRYR FRD  G  T  Y+ LLAIRL FVI+FEH+VF +  +ID ++PD+PE ++I+++R+ YMAK+AL
Sbjct:   28 FLSKLQTAGLQ-QEQVVVQSKTKTTYVLLSAPWNILCYYAEEISLRVPLQVETNEDSNWSEKILHKLHIPNILAQQVPNPPPDYYTCQFHTKKLERFLDHENKDTFFKTTQRHQILYEILSRTPYGAMKRGEVGIARLITEGAFTAAYPLHEGPYHMPRGPAGPESL-STRQILYQYWARWACWKKYQPLHHIREYFGEKVALYFAWLGFYTGWLLPAAVVGFFLSLFGIWLMVTDVPAQEVCHNGENIVMCPLCDI---CSYWNLSSICTTFRVGLLFDNGGTVFFSIFMSLWAVTFLEHWKRTCAVLSHRWDCSEFEESEERPRPEFAAMAPTTIRNPVTGAEEPHFPETSRFRRIITGNMVIIIMVAVVLIF--------------LIAIILYRSILSIIIYKSHNAFFIFSMCFLIVQSQRYFFTLRPTEMHRTQTKYEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYYKLFGIRNEDCGASGCLIELAQELLVIMVGKQVINNVQEFVLPKL----HPTQR--ENGANIT-ENVAP--WETDYELLMCEGLFSEYLEMVLQFGFITIFVAACPLAPFFALVNNWVEIRLDSQKFVCEYRRPVAERAQDIGIWFTILQVITYLAVISNAFLIAFTSDFLPRLYYRYTTEGSLRGYMDFTLSVAPNNFTQSHMQCRYRGFRDDKGHHTPEYYNLLAIRLGFVIIFEHVVFLIGRMIDWMVPDIPEEVEIKIKREQYMAKKAL 751
[Close]
BLAST of Anoctamin vs. Ensembl Cavefish
Match: si:dkey-83h2.5 (anoctamin-7-like [Source:NCBI gene;Acc:103022406])

HSP 1 Score: 668.307 bits (1723), Expect = 0.000e+0
Identity = 380/771 (49.29%), Postives = 526/771 (68.22%), Query Frame = 2 
Query:  332 LNDGIRRIDYVIVWEQDRIAINV-DPEXXXXXXXXXXXFHE----KLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLF--DNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKL--WSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSE--PCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYL 2611
             +DG+ RID+V+VW++    +   +PE +       +++ E    KL   GL  E++     K    ++ +  P+NI+C YAE ++ RVPLQ+      ++SE++L    IPN +  ++P  P  + T  F T +LE++L + N+DTFF TTQRHQ+  EIL+ T YG   +GE+GI R+I E  ++AAYPLHEGP  +P    G   L + RQIL++YWA+W+ + KYQP+ +IREY+GEK+A+YFAWLG YT WL PA++VG F+ ++GI  M +   ++E+C       MCPLC+    C YWNLS IC   ++  LFD+ GTVFFSIFMS+WAV FLE+WKR  A LS+RWD  ++EE +E+PRPE+ A+A     NPVTG EEP+FP   R +R++TG M I++M  +V+IF+I +I+YR +++I ++   N      A   AS++ +++NL++I+ L  VY  LA  LT+WEMHRT+T++ED  T+KV++F+FVNFYSS  YIAFFKGRF GYPG Y   FG+RNEDC    CL ELAQ++ +IMVG Q+INN+QE  LPK+  W++  K+ L+   + +G ++   +  W  DY+LL  EGLF EYLEM++QFGFITIFVAA PLAPFFAL+NNW+EIRLD+ K V   RRPVAERAQD+G WF IL +I  L++ISNAFLIAFTSDF+P+  Y+Y+    L GY++FTL+ APNN       CRYR FRD  G  T  Y+ LLAIRL FVI+FE    G +++
Sbjct:   41 FSDGVTRIDFVLVWDEPVTPLKASEPEDKTSTQATHRKWREEFLSKLQTAGLQQEQKEVVQSKTKTTYVLLSAPWNILCYYAEEISLRVPLQVETNEDSNWSEKILHKLHIPNILAQQVPNPPPDYYTCQFHTKKLERFLDHENKDTFFKTTQRHQILYEILSRTPYGAMKRGEVGIARLITEGAFTAAYPLHEGPYHMPRGPAGPESL-STRQILYQYWARWACWKKYQPLHHIREYFGEKVALYFAWLGFYTGWLLPAAVVGFFLSLFGIWLMVTDVPAQEVCHNGENIVMCPLCDI---CSYWNLSSICTTFRVGLLFDNGGTVFFSIFMSLWAVTFLEHWKRTCAVLSHRWDCSEFEESEERPRPEFAAMAPTTIRNPVTGAEEPHFPETSRFRRIITGNMVIIIMVAVVLIFLIAIILYRSILSIIIYKSHNAFFIFSAGRIASLTGSVLNLVVILLLSKVYTYLAQILTRWEMHRTQTKYEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYYKLFGIRNEDCGASGCLIELAQELLVIMVGKQVINNVQEFVLPKIKAWWN--KRKLHPTQRENGANITENVAPWETDYELLMCEGLFSEYLEMVLQFGFITIFVAACPLAPFFALVNNWVEIRLDSQKFVCEYRRPVAERAQDIGIWFTILQVITYLAVISNAFLIAFTSDFLPRLYYRYTTEGSLRGYMDFTLSVAPNNFTQSHMQCRYRGFRDDKGHHTPEYYNLLAIRLGFVIIFESSSGGQSWI 805
[Close]
BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 726.472 bits (1874), Expect = 0.000e+0
Identity = 395/788 (50.13%), Postives = 557/788 (70.69%), Query Frame = 2 
Query:  356 DYVIVWEQDRIAI-NVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWL-GLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLF--DNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDV--EPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSL---SEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            D+++VWE++      V P+        RK F   L K+GL  EE+I + EK+ I+++K+H P+ ++  YAE +N R+PLQI P    HFSER+LKF  +PN M  +LP  P  +    F+  +L+++LG  + +TFFS+TQRH + +EIL TT YG++ K E+G+DRM+ + I+SAA+PLHEG  +  T L    +   RRQ+L++YWA+W  ++KYQP+++IREY+GEKIA YFAWL G YT WL P +LVG+ VF  G LT+ + +  KEIC+  + ++MCPLC+    C+ WNLS+ C  ++M ++FD+PGT+F+SIF+S+W+V+FLE WKRK++ L+Y W      EE E+PRPEY ALA   R NP+TG +EPYF  + R  R +TG + + +M  +V+IF++ VI+Y+ L++I +F   N  L ++A   A+++  +V L+LI+ +  +Y  +A  LT+WEMHRT++E E+ LTVKV++F+ VN+YSS  Y+ FFKG+FNGYPG Y   FG RNE+C  G CL ELAQQ+ IIMVG QI+NN+QE+ LP +  W  R K     + ++ GK +  E  +W +DY+LL   GLFDEYLEM++QFGFITIFV AFPLAP FAL+NNW+EIRLDA K V   RR V ER + +G WF IL+ +  +SIISNAFLIAFTSDF+P+ +Y+Y++   LDGYV+FTLA+AP + +      CRYRDFRD +G LT FYW+LLA+RL+FVI+FEH+VF VA  ID LI DV   L+++++R+ Y+AKQAL
Sbjct:    3 DFMLVWEEEMENEETVPPQSMDEHDSLRKIFLTNLSKIGLLIEEDIMQGEKINIHYLKLHAPWQVLQCYAEEINLRMPLQIHPMTKTHFSERLLKFLHLPNIMHADLPRQPQEYYNCFFRKSKLDRFLGSDHPETFFSSTQRHVIVKEILNTTPYGKRKKAEVGLDRMLRDHIFSAAFPLHEGSYD-GTYLGLAPEQMTRRQVLYKYWARWGCWFKYQPLDHIREYFGEKIAFYFAWLLGFYTCWLLPPALVGLVVFFVGWLTLHNDSTVKEICENGSHYQMCPLCD---TCKVWNLSNTCNMAKMGHIFDYPGTIFYSIFISLWSVSFLEYWKRKSSSLTYHWGCTLVHEE-ERPRPEYAALAPLIRENPITGEKEPYFSEDDRTPRTVTGSIVLFLMISVVLIFLVTVILYQALLSISIFKTGNWFLATQATNIANMTGTLVFLVLIVIMARLYTTIADYLTRWEMHRTQSEHENALTVKVFIFQLVNYYSSPVYVGFFKGKFNGYPGNYGNLFGTRNENCPQGGCLIELAQQLFIIMVGKQILNNLQELILPIIQQWRQRRK-----LDEIRGKRLVQELNIWEDDYELLHNTGLFDEYLEMVMQFGFITIFVMAFPLAPLFALMNNWVEIRLDARKFVCRYRRSVVERVRGIGVWFDILSGLAHISIISNAFLIAFTSDFLPRLLYRYTYKSSLDGYVDFTLAYAPRDYVVANHTMCRYRDFRDQDGNLTLFYWKLLAVRLSFVIIFEHLVFLVARAIDWLIVDVAPDLKVKIKREEYLAKQAL 780
[Close]
BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 419.083 bits (1076), Expect = 1.602e-138
Identity = 215/365 (58.90%), Postives = 283/365 (77.53%), Query Frame = 2 
Query: 1619 NPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPK--LWSEDYKLLPYEGLFDEYLEM--IVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEP-CRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLN 2698
            N +L ++A   A++S+++VNLILI+ +G VY  LA +LT+WEMHRT+T++ED  T KV++F+FVNFYSS FY+AFFKGRF GYPG Y    G RNEDC  G CL ELAQQ+ IIMVG Q+INNIQE   PK+  W  + K     +  L G  V P+   W EDY+L+P EGLF+EYLEM  ++QFGFITIFVAAFPLAP FAL+NNW+E+RLDA K V   RRPVAERAQD+G WF IL+ +V +S+I NAFLIAFTS+F+PK +Y+Y+++  L GY+NFTL++AP+ +++E   RY+D+RD +GK T FYW+LLAIRL F+I FEH+VF ++ +ID L+PDVPESL+I+M+R+ Y+AKQAL +
Sbjct:   38 NAVLMTQAANIANISSSMVNLILILVMGQVYSSLAEQLTKWEMHRTQTQYEDAFTFKVFVFQFVNFYSSPFYVAFFKGRFVGYPGHYKKLLGTRNEDCGPGGCLIELAQQLIIIMVGKQVINNIQEFVFPKIKAWLQKRK-----LAALRGSHVAPESSRWEEDYELIPCEGLFEEYLEMGPVLQFGFITIFVAAFPLAPLFALLNNWVELRLDAQKFVCEYRRPVAERAQDIGVWFNILDALVNISVIINAFLIAFTSNFLPKLLYQYTYDRNLRGYINFTLSYAPDENIAEANLRYKDYRDQDGKHTLFYWKLLAIRLGFIIAFEHVVFFISRMIDWLVPDVPESLEIKMKRERYLAKQALAD 397
[Close]
BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 417.542 bits (1072), Expect = 3.621e-138
Identity = 215/367 (58.58%), Postives = 282/367 (76.84%), Query Frame = 2 
Query: 1619 NPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPK--LWSEDYKLLPYEGLFDEYLEM--IVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSE---PCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLN 2698
            N +L ++A   A++S+++VNLILI+ +G VY  LA +LT+WEMHRT+T++ED  T KV++F+FVNFYSS FY+AFFKGRF GYPG Y    G RNEDC  G CL ELAQQ+ IIMVG Q+INNIQE   PK+  W  + K     +  L G  V P+   W EDY+L+P EGLF+EYLEM  ++QFGFITIFVAAFPLAP FAL+NNW+E+RLDA K V   RRPVAERAQD+G WF IL+ +V +S+I NAFLIAFTS+F+PK +Y+Y+++  L GY+NFTL++AP++ +      CRY+D+RD +GK T FYW+LLAIRL F+I FEH+VF ++ +ID L+PDVPESL+I+M+R+ Y+AKQAL +
Sbjct:   35 NAVLMTQAANIANISSSMVNLILILVMGQVYSSLAEQLTKWEMHRTQTQYEDAFTFKVFVFQFVNFYSSPFYVAFFKGRFVGYPGHYKKLLGTRNEDCGPGGCLIELAQQLIIIMVGKQVINNIQEFVFPKIKAWLQKRK-----LAALRGSHVAPESSRWEEDYELIPCEGLFEEYLEMGPVLQFGFITIFVAAFPLAPLFALLNNWVELRLDAQKFVCEYRRPVAERAQDIGVWFNILDALVNISVIINAFLIAFTSNFLPKLLYQYTYDRNLRGYINFTLSYAPDDYVVNNYTHCRYKDYRDQDGKHTLFYWKLLAIRLGFIIAFEHVVFFISRMIDWLVPDVPESLEIKMKRERYLAKQALAD 396
[Close]
BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 406.371 bits (1043), Expect = 1.033e-133
Identity = 214/378 (56.61%), Postives = 280/378 (74.07%), Query Frame = 2 
Query: 1625 LLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLP-------------KLVTWFHRFKKGLNNMVQLSGKDVEPK--LWSEDYKLLPYEGLFDEYLEM--IVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSE---PCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLN 2698
            L+  +A   A++S+++VNLILI+ +G VY  LA +LT+WEMHRT+T++ED  T KV++F+FVNFYSS FY+AFFKGRF GYPG Y    G RNEDC  G CL ELAQQ+ IIMVG Q+INNIQE   P             K+  W  + K     +  L G  V P+   W EDY+L+P EGLF+EYLEM  ++QFGFITIFVAAFPLAP FAL+NNW+E+RLDA K V   RRPVAERAQD+G WF IL+ +V +S+I NAFLIAFTS+F+PK +Y+Y+++  L GY+NFTL++AP++ +      CRY+D+RD +GK T FYW+LLAIRL F+I FEH+VF ++ +ID L+PDVPESL+I+M+R+ Y+AKQAL +
Sbjct:   32 LMTQQAANIANISSSMVNLILILVMGQVYSSLAEQLTKWEMHRTQTQYEDAFTFKVFVFQFVNFYSSPFYVAFFKGRFVGYPGHYKKLLGTRNEDCGPGGCLIELAQQLIIIMVGKQVINNIQEFVFPLTLPPPAPRSCRRKIKAWLQKRK-----LAALRGSHVAPESSRWEEDYELIPCEGLFEEYLEMGPVLQFGFITIFVAAFPLAPLFALLNNWVELRLDAQKFVCEYRRPVAERAQDIGVWFNILDALVNISVIINAFLIAFTSNFLPKLLYQYTYDRNLRGYINFTLSYAPDDYVVNNYTHCRYKDYRDQDGKHTLFYWKLLAIRLGFIIAFEHVVFFISRMIDWLVPDVPESLEIKMKRERYLAKQALAD 404
[Close]
BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000399.1 (pep scaffold:Pmarinus_7.0:GL477564:2673:43187:-1 gene:ENSPMAG00000000358.1 transcript:ENSPMAT00000000399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 378.637 bits (971), Expect = 3.294e-118
Identity = 265/676 (39.20%), Postives = 395/676 (58.43%), Query Frame = 2 
Query:  515 NFIKIHIPFNIMCIYAEALNFRVPLQI-----GPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAA----FKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKG--EIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVN-----PVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFD--NPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFF-GLRNEDCSNGSCLFELAQQMAIIMVGNQII-NNIQEIFLPK---LVTWFHR--FKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYK--YSHNFLLDGYVNFTLAW 2461
             +++IH P+ ++   AE L  ++P +            H     +   L PN     +P+S +  +       F  D+ +K     +ED+FF +  R ++  EIL      + TKG  ++GI  +I   +Y++A+PLH+G      +L G     N R++L + WA ++KFYKYQP+E I++Y+GEKI +YFAWLG+YT  L P S+VGI VF+YG L  +      E C       MCP C+  K C+Y  LS+ C   + ++LFD+  TV FSIFM++WA  FLE+WKR    L+Y WD    EE +++ RPEY A   EK+         T  EE       ++   L    CI+ M ++    ++G+I YRI + + L +  +P L+S        +A ++NL++I+ L  +Y  +A  LT  E+ +TE EFE  L  K ++ +FVN Y+SI Y+AF KGR  GYP KY       R E+C+ G CL ELA Q+ IIM+G Q++ NN+ E+ +PK   L  + H+    K  +++ +  G +    L  +DY+L P+ GL  EY+EM++QFGF+T+FVA+FPLAPFFAL+NN +EIRLD  K V   RRP A RA+D+GTW++ILN + KL++I NA +IA TSDF+P+ +Y   YS +  L GYVN+TL++
Sbjct:  117 GYLRIHAPWLVLIREAEFLKIKMPTKKVFEMKQSSGVLHGLGARINHALQPN-----VPHSQEALSQKKLSFPFSRDK-QKLFDIKSEDSFFDSATRSRIVFEILKRV---KCTKGPYKMGITSLIANGVYTSAFPLHDG------ELHGSE--VNDRKLLHDEWASYNKFYKYQPLELIKKYFGEKIGLYFAWLGVYTQMLIPPSVVGIAVFLYGWLAAEKDIPGFETCVIGQNITMCPTCD--KLCKYKRLSENCDRVRSSHLFDNITTVLFSIFMALWATTFLEHWKRIETRLNYTWDLNGMEESEQQLRPEYEAKLLEKKRKVDIKLAKTQTEEYGLSWRDQLPSFLINCSCILFMVLLSFAIVVGMIFYRITMNVLLANSTDPYLKSNRSAIIMATAFLINLVIILILDEIYGSIARWLTVIEVPKTEEEFETRLIFKSFMLKFVNSYTSIIYVAFLKGRITGYPKKYYYILPNYRMEECAPGGCLQELALQLCIIMLGKQLLQNNLFEVGIPKIKKLCRYLHKKDHHKKASHLKEEDGME----LGCKDYELEPFTGLNPEYMEMVIQFGFVTLFVASFPLAPFFALLNNVIEIRLDGKKFVTELRRPTAVRAKDIGTWYVILNGVAKLAVIINALVIALTSDFVPRLIYMYFYSPDGSLRGYVNYTLSY 769
[Close]
BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO49855 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REV0])

HSP 1 Score: 741.11 bits (1912), Expect = 0.000e+0
Identity = 397/773 (51.36%), Postives = 544/773 (70.38%), Query Frame = 2 
Query:  443 FHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVD-LWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSY--TISKEICDTNN-TFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKY--SHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMTKNEMGSLKRGESL 2743
            F E L K  L  EEEI + +K+ ++FIKIH+P+ ++  YAE L+FR PL++G     ++SER+L+ F +PN  K E+P  P  F T  F+ ++L K++G  + D++F+  +R +VA EIL T  YG++ +GEIGI+R+++E ++ A YPLH        +  G    L    Q+L EYW +W K+ KYQP+++IR+Y+GEKI IYFAWLG YTAWL   S +G+ VF+YG+ T+ S     + E+CD    TF+MCPLC+ E GC+YW+L   C   ++ YLFD+  TVFF++F+S W+  FLE WKRK   L+Y WD ++YEEE E+PRP + ALA     NPVTGI EP+FP   R  R+ +G+  +  M  +V++F++GVI+Y++L+  PL  NP  R+ AL  A+ + A VNL +IM L  VYE++A  LT WEMHRT+TE+ED LT KV++F+F NFYSSIFY+AFFKG+  GYPG Y   FGLR E+CS G CL ELAQQ+ IIMVG Q+INN+QEI +P +  W  R K+G       S  +++P+ W +D++L+  EGLF EYLEMI+QFGFITIFVAAFPLAPFFAL NN  EIR+D+ K V   RRP+A+RAQD+G WF IL+ + K+++ISNAFLIAFTS F+PK +Y+Y  S NF L+GY N+TLAWAP N+  +PCRY++FRD  G  T FYW LLA+RL FVI+FEH+VF V  LID+++PD+P  L+I ++R+ Y+AKQAL +   N MGS + GE +
Sbjct:   24 FLENLAKSQLEFEEEITQDKKVKLHFIKIHVPWEVLLFYAEELSFRAPLEVGLNTKVNWSERMLEKFHMPNIFKEEVPNPPPDFFTCTFQANKLNKFIGSDDPDSYFTDVERTRVAYEILETAPYGKRQRGEIGIERLVEEGVFKAGYPLH---VNCYLNQQGYSPFLIYVSQVLKEYWGRWGKWLKYQPLDHIRDYFGEKIGIYFAWLGQYTAWLIMPSFLGLLVFLYGVATINSSDNKPALEVCDNPPWTFRMCPLCDEELGCQYWDLHISCKSGKIAYLFDNASTVFFAVFVSFWSCFFLEYWKRKEVTLAYHWDVLEYEEEAERPRPTFAALAPTVERNPVTGILEPHFPDEKRKPRLFSGIAIVFTMVSLVLVFMVGVIVYKLLVYRPLARNPSTRAYALQIANSTGAFVNLTIIMILSRVYERVALALTHWEMHRTQTEYEDSLTFKVFVFQFANFYSSIFYVAFFKGKLVGYPGHYRRLFGLRQEECSPGGCLMELAQQLVIIMVGKQMINNVQEIAIPLVKQWIKRKKRG------TSKDEIKPR-WEQDFELVENEGLFQEYLEMILQFGFITIFVAAFPLAPFFALANNIFEIRIDSDKFVCEVRRPIADRAQDIGIWFNILDSVAKIAVISNAFLIAFTSTFLPKLLYRYAVSENFSLEGYTNYTLAWAPRNTTLKPCRYQEFRDPEGHFTVFYWHLLALRLGFVIMFEHVVFFVMRLIDMMVPDIPTELEIIIKREAYLAKQALADH-HNLMGSGESGEEV 785
[Close]
BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO49854 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REU8])

HSP 1 Score: 694.115 bits (1790), Expect = 0.000e+0
Identity = 376/701 (53.64%), Postives = 500/701 (71.33%), Query Frame = 2 
Query:  629 VLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYY-----GEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYT--ISKEICDTNN-TFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKD---VEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYK--YSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            +LK F +P   K+++P +P  + T  FK+++L K+LG  N DT+F+ T+R +VA EIL T VYGR+ KGEIGI R++DE  YSAAYPLH GP   P ++       N RQ+L EYWA+W  +YKYQP+++IR+ Y     G KIAIYFAWLG YTAWL   S+VG+ VF+Y   T+       + E+CD    T+ MCP C  E GC  W+L   C  ++  YLFD+P TV +SIF+S WAV FLE WKRK   + + WD +++E E+E+PRP + ALA     NP+TG+ EPYFP   R  R+L+G+  I  M  +V++F++GVI+Y++L+  PL+ NP L+  A  FAS + A++NLI+IM L  VYEKLA  L  WEMHRT+TE+ED+LT+KV++F+F NFYSSIFYIAFFKG+F GYPG Y   FGLRNE+CS G CL ELAQQ+A+IM+G Q+I NIQE+F+P+L       KK L N  + + KD   ++P+ W  DY+LL  EGLF EYLEM++Q+GFIT+FVAAFPLAPFFAL NN  EIR+DA K V   RR  A+RAQD+G WF IL+ I KL++ISNAFLIAFTS+F+PK +Y    S N  L+GY+N++LAWAP N+ S+PCRYR FRD +G  TRF+W LL +RL FVI+FEH VFG++ LID+ +PD+P +L+  ++R+ Y+A QAL
Sbjct:    1 MLKKFHLPCPFKDDVPNTPPDYFTTTFKSNKLNKFLGSDNPDTYFTDTERARVASEILETAVYGRRQKGEIGISRLVDEGTYSAAYPLHVGP-HGPDEMK-----LNMRQVLKEYWARWGAWYKYQPLDHIRQAYEREGGGLKIAIYFAWLGQYTAWLIMPSVVGLIVFIYSFATINGPNNMPALEMCDHPAWTYPMCPNC--EVGCSVWDLKKSCSRAKHAYLFDNPMTVAYSIFVSFWAVLFLEFWKRKEVTIGHAWDVLEFESEEERPRPTFAALAPAVERNPITGLLEPYFPDEKRSPRVLSGIAIICGMVSLVMLFMVGVIVYKLLVIHPLYKNPNLQPYANQFASGTGAVLNLIIIMILSRVYEKLALLLNHWEMHRTQTEYEDNLTLKVFIFQFTNFYSSIFYIAFFKGKFVGYPGNYGTIFGLRNEECSPGGCLIELAQQLAVIMIGKQVIGNIQEVFIPEL-------KKYLKNRKRQNSKDEDEIKPR-WEADYELLDNEGLFQEYLEMVIQYGFITLFVAAFPLAPFFALANNVFEIRIDADKFVNDLRRSTADRAQDIGVWFTILDSITKLAVISNAFLIAFTSEFLPKLLYAGVVSPNQSLEGYLNYSLAWAPPNTTSQPCRYRGFRDEDGNFTRFFWHLLTMRLVFVILFEHFVFGISTLIDVAVPDIPRALEDTIKREKYVATQAL 685
[Close]
BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO48048 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU7])

HSP 1 Score: 486.493 bits (1251), Expect = 2.228e-158
Identity = 323/852 (37.91%), Postives = 482/852 (56.57%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXX---XXXXXFHEKLLKMGLSCXXXXXXX---XKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDL-WNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNL-SDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDN--PLLRSK-------ALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRF-NGYPGKYSLFFG-LRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSH-----NFLLDGYVNFTLA---------WAPNNSLSEP----------CRYRDFRDVNG--KLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMTKNEMGSLKRGESL 2743
            + N G  ++DYV+V+E  +   + DP+   ++      R  F   L + GL  E E   S   +K+  +F+K+H+P+  +   AE L  + PLQ          E++   F I +   + +P  P CF  A FK  +++KY+G    +  F+   RH V + I   T +    KG +G+ +++ E  Y A YPLH+G      D++G+     N RQ L + W+   + +KYQP++ ++ YYG  IA+YFAWLG YTA L P ++VG+ VF+YGI +  +    ++ CDTNN F MCPLC  ++ C YW+L S  C Y+++T+ FD+ GTVF +IF SVWA  FLE WKR+ A L+Y W   ++EEE+E+ RPE+ A A   + N +TG  EP+ P     +R       +  M ++VI  +IGV++YR  +   L  N    +R++       + I  S++AA++NL+ I  L L Y +LA  LT WE  RT+T++ED  T K+YLF+FVN Y+SIFYIAFFK     G PG+Y    G  R E CS   C  EL  QM IIMVG QII NI E+ +P ++TW    K+  N  +        P+ + +DY L P E   LF EYLE+++Q+GF+T+F+AAFPLAP F+L+N+ +EIR+DA   V   RRP    A+D+G W+ IL  + +LS++ NAF+++FTS+FIPK VYK  +        L+GY+N +L+         W P  +   P          CRY+ + D     K  + YW ++A RL FV VF++ V+ +   I   +PD P SL++  +R+ ++ K+ L N  K   G L R   +
Sbjct:   16 FFNKGGHKVDYVLVYETCQEREDKDPKFAAKMADFERKRDAFEAALSEQGLVIERESITSPQNDKVKRHFVKLHVPWRTLSSKAEELMLKAPLQENDIDLKTTGEKIFDPFRIKD---SSIPEKPKCF-MAYFKERKVDKYMGKAEPEKMFTALDRHYVVQRICYATRFAEGPKG-VGLKQLVYEGAYCANYPLHDGD----DDVIGESSYPSNDRQRLKKDWSSMKRIFKYQPLDTVKGYYGTAIALYFAWLGFYTAMLIPLAIVGLLVFIYGIGSSATSPTVRDACDTNNKFYMCPLC--DRTCSYWDLVSTTCMYARVTHFFDNDGTVFLAIFTSVWATLFLEFWKRRQAVLAYEWHVANFEEEEEQIRPEFAATAPTLKKNIITGKLEPHIPRRTLYQRYGAIGSVVAFMILLVIAAVIGVVVYRAAVFAALSGNSDSTIRARYAMIAIGSRIITSMTAALINLLCINILKLFYNRLAVWLTNWENPRTKTDYEDSFTYKMYLFQFVNTYASIFYIAFFKSEIVVGTPGRYKRIAGKYRLEGCSAQGCFLELCVQMLIIMVGQQIIGNITEVAIPAIMTWIKERKEPKNKQL--------PQ-FEQDYNLQPQEEHNLFWEYLEIVLQYGFVTMFIAAFPLAPLFSLLNSIVEIRVDAINFVSQFRRPDTMIAEDIGAWYRILETLTRLSVLINAFVLSFTSEFIPKLVYKLKYAPEGSEGTLEGYLNNSLSAINVTVMEEWEPGTAPLNPTKNLNYTETFCRYKGYHDNTYPFKFNKQYWHVIAARLAFVFVFQYTVYAITSFIAWAVPDQPRSLELRSKREEHLTKKILYN--KGRSGRLSRSNDV 845
[Close]
BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO48050 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU9])

HSP 1 Score: 471.855 bits (1213), Expect = 3.500e-153
Identity = 307/800 (38.38%), Postives = 456/800 (57.00%), Query Frame = 2 
Query:  443 FHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVL-KFFLIPNFMKNELPYSPDCFA------TAAFK----TDQLEK---YLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDT--NNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVT--GIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXP---LFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFN-GYPGKYSLFFG-LRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVE--PKLWSEDYKL--LPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVY--KYSHNFLLDGYVNFTL------------------------AWAPNNSLSEPCRYRDFRDVN--GKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYM 2677
            + E L K GL  E E  +++K   +F+KIH P++++   AE +  + P++        +SE+ L + F+     ++ L     C         A F+      +L+K   ++GY +++TFFS  +R ++   I +   +G + + + GI R+I +  Y+AAYPLH GP EV      K    N RQ L   WA++ +++KYQP + I++Y+G +I +YFAWLG Y A L PA++ G+ VF+YGI     +   K+IC+      F MCPLC+  K C YW+L   C Y+   + FD+  TV F+IFMS+WA  FLE WKR+ A L+Y W  + YE+++E+PRPE++   T  + +  +  G   P+ P  L+  R L GV+ +V   + +++  +  ++            + +P +R +A +  S++AAI+NLI I  L  VYEKLA  LT+WE  RTET+F+D  T K+YLF+FVN Y+SIFYIAFFK     G PG Y  F G  R + CS+G CL +L  Q+ IIMVG QII NI EI +P L+ W+         M Q   +  E  P+ W  DYKL  LP   LF EYLE+++QFGF+T+FVAAFPLAP FAL+N   E+R+DA   V   RRP   RAQD+G W  I+  +  +S++ NAF+IAFTSDFIP+ VY   YS +  L GY+N +L                        A+   N   E CRY  + +     ++++ YW ++A RL FV  F++IV+ V   +  L+PD P  L++ ++R+ Y+
Sbjct:   26 YEENLKKAGLELEHEEGDNKKRKTHFVKIHTPWDVLAATAEEMMMKSPIRDSDIEIKSWSEKHLSEEFVTSIRSRDPLKIHDSCITPPKKQFVAYFRKVINNPRLQKKQFFVGYHDKNTFFSAAERSRMTERICSQQRFGEE-RFDQGIKRLIHQGTYTAAYPLHSGPEEVSR----KGHPSNERQKLRRDWARFGRWFKYQPYDAIKDYFGTEIGLYFAWLGFYAAMLVPAAIFGVAVFIYGIAQSTIFPPVKDICNKAYEAEFYMCPLCD--KQCPYWSLVVNCPYAIWVHAFDNDSTVVFAIFMSIWATVFLEFWKRRQAVLAYEWHMMHYEDQEEQPRPEFIVTVTTLKKDKASQWGGMVPHVP-KLQQYRKLAGVVSLVAFMIALVLSAVVGVVIYRASVYGSLMAYPDPQVRKQAKMTTSITAAILNLICINLLKFVYEKLAMFLTEWENPRTETDFKDSFTYKMYLFQFVNNYASIFYIAFFKLNLVIGTPGNYRRFAGEYRLDGCSSGGCLMDLCIQLVIIMVGQQIIGNITEIAIPGLLKWW--------KMRQAQKEAFEEIPR-WEVDYKLNTLPEHHLFWEYLEVVLQFGFVTMFVAAFPLAPLFALVNAVFELRVDAINFVCQFRRPTPRRAQDIGAWMSIMQGLANISVLVNAFVIAFTSDFIPRLVYTTAYSPDGTLRGYLNNSLSYFNVKDYDRMGAIGAREKPGDNYAYTVLNYTREYCRYPGYHEPEFPYEVSKQYWHVIAARLAFVFAFQYIVYAVTKFVAWLVPDRPRHLELRIKRQEYL 808
[Close]
BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO48307 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RJQ8])

HSP 1 Score: 459.914 bits (1182), Expect = 5.236e-149
Identity = 304/812 (37.44%), Postives = 472/812 (58.13%), Query Frame = 2 
Query:  353 IDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMIN-FIKIHIPFNIMCIYAEALNFRVPL-QIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDC-------FATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEG-PAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPL--LRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFK-GRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEG--LFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVY--KYSHNFLLDGYVNFTLA-------------WAPNNSLSEPCRYRDFRDVNGK--LTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            +D+V+V+E+ +     +        E R+ F E L+K GL  +    +  + +   F+ IH P++++  +AE +  R PL +  PP      +++ +  LI N+ K   P  P C       F    F  D+ + +L  +++D FFS   R ++   IL    +  +   + GIDR++   +Y AAYPLHEG     PTD        N R+ L   WA + ++Y++QP+  I+ Y+G ++  YFAWLG Y   L  A+LVG+F F+ G+ +++S+  +KEICD  N               YW+L   C YS++T+LFDH GTVFF+ FM++W+  FLE WKR+   L++ WD +D++EE E  RP++V    E+R NP+TGI EP+ P   ++ +     + +++M ++VI  ++GVI+YR  ++  L   P   +R  A +  S++A+ +NL+ I  L  VY  +A  LT WE  RT T++ D LT K++LF+ VN YSS+FYIAFFK     G PG+Y+   G R E C    CL EL  Q+AII+ G Q I+ I +I LP L  W++R  +   N+++    D     W  DY L P     +F EY +M++QFGF+T+FVAAFPLAP FAL+NN LE+R+DA   V++TRRPVAERA+++G+W  IL  + + +I+ N+F+IAFTS+FIP+ VY   YS +  L+GYVN +L+               P  +L     Y+++ +       +R ++ +LA RL FVI+F+++V    +LI+ L+PDVP SL+I M+ + Y+A++ L
Sbjct:    1 VDFVMVYEETKGKDEEEIRDEEEKAEMRRNFEEHLIKEGLLLQHTDSDLNEEVNKVFVLIHAPWDVLTRFAEKMLLRFPLREASPPPAAQGFDKIPE--LISNWSKIFDP--PSCGITKEKRFVHGLFSRDKKDSFL-ISDKDKFFSDIDRSRIVARILRLCRFSSEPD-DFGIDRLLHRGVYGAAYPLHEGLSTSYPTDSSA-----NHREYLQYSWASFRQWYRFQPLNEIKSYFGTRVGFYFAWLGTYNLMLVIAALVGLFCFIGGLASVESFVPAKEICDKANE-------------NYWSLHTSCRYSKITHLFDHEGTVFFAAFMALWSSLFLEVWKRQQTSLAFEWDMLDFDEELEPARPQFVEAVKERRPNPITGILEPFVPYAKQLIKQTCAFVVVLLMILLVIAAVVGVIVYRAAMSAALHSYPREDVRRGARVITSITASTINLVAITILSYVYNYIAVFLTNWENPRTRTQYTDALTFKMFLFQSVNMYSSLFYIAFFKSAMIVGVPGRYTRIGGGRLEGCDPSGCLIELCIQLAIILGGKQAISLIIKIVLPCLWRWWNR--RSQRNLLETGELD----RWELDYLLNPEPDFRMFYEYHDMVLQFGFVTMFVAAFPLAPLFALLNNILELRIDAINFVVTTRRPVAERARNIGSWLGILQTLSRFAILVNSFVIAFTSEFIPRLVYTVAYSPDGSLNGYVNNSLSSFNVRDFERQSLPQDPFQNLPYNNTYKEYFESTSPYMYSRQFYYVLAARLAFVIIFQYLVIFTVFLINWLVPDVPYSLEIRMKHEKYIAQKML 782
[Close]
BLAST of Anoctamin vs. Ensembl Medaka
Match: si:dkey-83h2.5 (anoctamin 7 [Source:NCBI gene;Acc:101162585])

HSP 1 Score: 744.577 bits (1921), Expect = 0.000e+0
Identity = 395/822 (48.05%), Postives = 563/822 (68.49%), Query Frame = 2 
Query:  314 LCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLF--DNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNN----SLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMTKNEMGSLK-RGESLLVKAD 2758
            +C     +D + R+D+V+VWE+   +            ++R+ F  +L  +GL  E+      K  + F+ +  P++++C YAE ++ RVPLQ+      ++S+++L    +PN +  ++P  P  F T  F+T++L+++LG  N++TFF TTQRHQV  EILA T YG   KGE+GIDR+++E +++AAYPLHEG  ++PT  +    L   RQIL+ YWA+WS + +YQP+++IREY+GEK+A+YFAW+G+YT WL  ++LVG  +F+ G   M     +KE+CD+ NTF MCP+CN    C YWN S+IC   +   LFD+ GTVF S+FMS+WAV FLE WKR ++ LS+RWD  D+++  E+PRPE+ A+A     NP+TG EEPYFP   R+ R LTG M IV+M  +V++F+I +I+YR +++I +   +N      A   AS+S +++NL+LI+ L  VY  LA+ LT+WEMHRT++++ED   +KV++F+FVNFYSS  YIAFFKGRF GYPG Y   FG+RNEDC  G CL ELAQ+M +IMVG Q+INN+QE   PK+++W+ R K  ++  V+  G+++ P  W  DY+LL  EGLF EYLEM++QFGF+TIFVAA PLAP  ALINNWLEIRLDA K V   RRPV ERAQD+G WF IL  I   +++SNAFLIAFTS F+P+  ++Y+ +  L GY NFTLA +P++     L+  CRYR FRDV G     Y+ LLAIRL F+I+FEH+VF V  LID+++PD+PE ++++M+R++YMAK+AL       +G +K  G+ + V  D
Sbjct:   32 VCDRNVFSDKVTRVDFVLVWEEPHCSNEDSSAADPTHVQWREEFLRRLEGVGLLQEKTEVPQMKKRVCFVLLSAPWDVLCFYAEEISLRVPLQVVSTSDVNWSQKILSRLSLPNPLVQDVPNPPPDFYTCQFRTNKLQRFLGSENQETFFKTTQRHQVLYEILARTPYGSVRKGEVGIDRLVNEGVFTAAYPLHEGDFQLPTPPVDPQSL-GLRQILYAYWARWSCWRRYQPLDHIREYFGEKVALYFAWIGVYTGWLLLSALVGTVIFLMGFWIMAVDVPAKEVCDSGNTFIMCPICNI---CSYWNYSNICHTYKAGLLFDNAGTVFLSVFMSLWAVTFLEYWKRTSSALSHRWDCSDFQDIAERPRPEFTAMAPMTTRNPITGAEEPYFPEKKRLNRTLTGCMVIVLMVSVVLMFLIAIILYRTILSIIIHRSNNSFFSVSAGRIASLSGSVLNLLLILLLSRVYTSLAHLLTRWEMHRTQSKYEDMFILKVFVFQFVNFYSSPVYIAFFKGRFVGYPGNYKSLFGVRNEDCGAGGCLMELAQEMLVIMVGKQLINNVQEFISPKVMSWWQRMK--MSPQVKKKGEELSP--WEADYQLLVCEGLFGEYLEMVLQFGFVTIFVAACPLAPLCALINNWLEIRLDAQKFVTEYRRPVVERAQDIGIWFPILQFITHTAVLSNAFLIAFTSSFVPRLYFRYTKDSSLSGYTNFTLATSPHSFNQQHLNTSCRYRGFRDVKGDFLPEYFHLLAIRLGFIIIFEHVVFFVGSLIDMMVPDIPEEVEMKMKREHYMAKEALAE--NQSLGKIKIPGQQIDVLTD 843
[Close]
BLAST of Anoctamin vs. Ensembl Medaka
Match: ano3 (anoctamin 3 [Source:NCBI gene;Acc:101164148])

HSP 1 Score: 539.65 bits (1389), Expect = 6.348e-177
Identity = 349/838 (41.65%), Postives = 496/838 (59.19%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLK-----FFLIPNFMKNELPYSP--------------DCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEG--PAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPL--FDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYS-LFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKL--WSEDYKLLPY--EGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVY-----------KYSHNFLLDGYVNFTLA----WAPNN-SLSEPCRYRDFR-----DVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            +  DG +RIDY++V+++    +             R  F + L   GL  E+E   +   ++  +K+H  ++ +C YAE +N R+P +       +FS++  K     F L    +KN  P +P              DC+ TA F   ++  +   +N +TFFS + R ++   +L  T Y    K ++GI+R++    Y AA+P HEG   +  P    G     N R +L+E WA+W  +YKYQP++ IR Y+GEKI +YFAWLG YT  L PA+LVG+FVF+YG+ TM S  +SKEIC+ N T  MCP+C  E+ C  W LSD C Y+++T+LFD+ GTVFF+IFM++WA  FLE WKR+ AEL+Y WD +D+EEE+E+ RP++ A  + K RVNP++G  EP+ P + ++ R++  V  I  M  +V+  +  V+++R++       F    ++       S +   +N ++IMSL +VYEK+AY LT  E  RTE+E+E+   +K++LF+FVN  SS FYIAFF GRF G PGKYS LF   R E+C    CL +L  QM +IM   QI NN  E+  P L  W+ R K          G++VE +L  W +D+ L P    GL DEYLEM++QFGF TIFVAAFPLAP  AL+NN +EIRLDA K V   RRP+  RA D+G W  IL  I  L++I+NAF+IA TSD+IP+ VY           ++  N  L GYVN +L+    W  NN S+S  CRYRD+R      V  K T  +W +LA RL F+IVFEH+VFG+   I  LIPD+P+ L   MRR+ Y+ ++ +
Sbjct:  137 FFRDGKKRIDYILVYKKSSPQVE-----------KRCTFEKNLRAEGLMLEKEHSLTNNDIM-LVKVHASWDTLCKYAERMNIRMPFR----KKCYFSDKRSKGLGSRFHLRCQQIKNWFPKNPMKLDKEALPDLEESDCY-TAPFSRARMHHFT-ISNRETFFSNSTRSRIVHHVLQRTKY-EDGKSKMGINRLLGNNTYEAAFPPHEGGYKSRHPIKTHGPQ---NHRHLLYERWARWGIWYKYQPLDLIRRYFGEKIGLYFAWLGWYTGMLIPAALVGVFVFLYGLFTMDSSQVSKEICEANTTI-MCPMC--EETCEPWTLSDSCVYAKVTHLFDNGGTVFFAIFMAIWATVFLEFWKRRRAELTYDWDLIDWEEEEEELRPQFEAKYSRKERVNPISGKPEPFQPFSDKLSRLMVSVSGIFFMISLVLTAVFAVVVFRLIAMEKFASFRWHFVKKNLQFATSGTGVCLNFMIIMSLNVVYEKVAYLLTNLEHPRTESEWENSFALKMFLFQFVNLNSSTFYIAFFLGRFAGRPGKYSKLFNRWRLEECHPSGCLIDLCLQMGVIMFFKQIWNNFMELGYPLLQNWWSRRKI---KKGGGGGQNVETQLPQWDKDWNLQPMNAHGLVDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGILEGIGVLAVITNAFVIAITSDYIPRFVYAFKYGPCMDKGQHHENECLQGYVNSSLSVFDMWEVNNSSMSRYCRYRDYRAPPWSSVPYKFTLQFWHVLAARLAFIIVFEHLVFGIKSFIAYLIPDMPKDLCDRMRREKYLMQEMM 946
[Close]
BLAST of Anoctamin vs. Ensembl Medaka
Match: ano3 (anoctamin 3 [Source:NCBI gene;Acc:101164148])

HSP 1 Score: 504.212 bits (1297), Expect = 5.389e-164
Identity = 349/879 (39.70%), Postives = 497/879 (56.54%), Query Frame = 2 
Query:  203 SPKFDCQMEKLQLINLKKDKNK--------ESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSP--------------DCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEG--PAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEK-RVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPL--FDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYS-LFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKL--WSEDYKLLPY--EGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVY--KYSHNF-----LLDGYVNFTLA----WAPNN-SLSEPCRYRDFR-----DVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            SP    ++E L L ++  +KN         E   E+  L+          +  DG +RIDY++V+++    +             R  F + L   GL  E+E   +   ++  +K+H  ++ +C YAE +N R+P +       +FS++  K       +KN  P +P              DC+ TA F   ++  +   +N +TFFS + R ++   +L  T Y    K ++GI+R++    Y AA+P HEG   +  P    G     N R +L+E WA+W  +YKYQP++ IR Y+GEKI +YFAWLG YT  L PA+LVG+FVF+YG+ TM S  +SKEIC+ N T  MCP+C  E+ C  W LSD C Y+++     H   + FS      A  FLE WKR+ AEL+Y WD +D+EEE+E+ RP++ A  + K RVNP++G  EP+ P + ++ R++  V  I  M  +V+  +  V+++R++       F    ++       S +   +N ++IMSL +VYEK+AY LT  E  RTE+E+E+   +K++LF+FVN  SS FYIAFF GRF G PGKYS LF   R E+C    CL +L  QM +IM   QI NN  E+  P L  W+ R K          G++VE +L  W +D+ L P    GL DEYLEM++QFGF TIFVAAFPLAP  AL+NN +EIRLDA K V   RRP+  RA D+G W  IL  I  L++I+NAF+IA TSD+IP+ VY  KY   F      L GYVN +L+    W  NN S+S  CRYRD+R      V  K T  +W +LA RL F+IVFEH+VFG+   I  LIPD+P+ L   MRR+ Y+ ++ +
Sbjct:   43 SPDPKPEIEGLSLDSVLSNKNASFLNLNWIELTGESFFLQEKDPSNSSGLFFRDGKKRIDYILVYKKSSPQVE-----------KRCTFEKNLRAEGLMLEKEHSLTNNDIM-LVKVHASWDTLCKYAERMNIRMPFR----KKCYFSDKRSKGLGRCQQIKNWFPKNPMKLDKEALPDLEESDCY-TAPFSRARMHHFT-ISNRETFFSNSTRSRIVHHVLQRTKY-EDGKSKMGINRLLGNNTYEAAFPPHEGGYKSRHPIKTHGPQ---NHRHLLYERWARWGIWYKYQPLDLIRRYFGEKIGLYFAWLGWYTGMLIPAALVGVFVFLYGLFTMDSSQVSKEICEANTTI-MCPMC--EETCEPWTLSDSCVYAKVREQL-HGECLIFSA-----ATVFLEFWKRRRAELTYDWDLIDWEEEEEELRPQFEAKYSRKERVNPISGKPEPFQPFSDKLSRLMVSVSGIFFMISLVLTAVFAVVVFRLIAMEKFASFRWHFVKKNLQFATSGTGVCLNFMIIMSLNVVYEKVAYLLTNLEHPRTESEWENSFALKMFLFQFVNLNSSTFYIAFFLGRFAGRPGKYSKLFNRWRLEECHPSGCLIDLCLQMGVIMFFKQIWNNFMELGYPLLQNWWSRRKI---KKGGGGGQNVETQLPQWDKDWNLQPMNAHGLVDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGILEGIGVLAVITNAFVIAITSDYIPRFVYAFKYGPCFSGPSRCLQGYVNSSLSVFDMWEVNNSSMSRYCRYRDYRAPPWSSVPYKFTLQFWHVLAARLAFIIVFEHLVFGIKSFIAYLIPDMPKDLCDRMRREKYLMQEMM 887
[Close]
BLAST of Anoctamin vs. Ensembl Medaka
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:101164640])

HSP 1 Score: 499.975 bits (1286), Expect = 8.367e-163
Identity = 321/842 (38.12%), Postives = 475/842 (56.41%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXK-MMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGE---IGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEIC--DTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKP--RPEYVALATEKRVNPVTGIEEPYFPVNLRMKRM-LTGXXXX---XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKAL-------IFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFG----LRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----FLLDGYVNFTLAW-------APN-----------NSLSEPCRYRDFRDVNGKLTRF-----YWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLN 2698
            +  DG+RRID+V+ +        VD +   R  E R+ F   L+K+GL  E E +         F+KIH P+ ++  YA+ L  +VP +      P  SE  + +   P  +   +      F TA F   + + +L   + D FF  + R+++   IL+   Y R   GE    GI R+++   Y+AA+PLH+      +     V+  + R  L++YWA +  F+K QP+  IR+YYGEKI +YFAWLG YT  LF A++VG   FVYG+LT      SKEIC  +      MCPLC+  K C +W L+  C  S  ++LFD+ GTVFF+IFM +W   FLE WKR+ A L Y WD VD+EEE ++   RPEY      +++N +T   EPY P+  +  R+ L+G   +    ++   +I  I   +      A  + D+P    + +       +  SV+A+ +N ++IM L L+YE++A  +T  E+ +T  E+E+ LTVK++LF+FVN+YSS FY+AFFKG+F GYPG Y+  FG    LRNE+C  G CL EL  Q+ I+M G Q+  NIQE  +P L+ W+   +K  +    L  +      W +D+ L  +   GLF EYLEM++QFGFIT+FVA+FPLAP  AL NN +EIR+DA KL    RRPVA +A  +G W  ILN +  LS+++NAF++AFTSD IP+ VY Y++       + GY+N +L+         PN           NS    CRYRD+R+  G   ++     +W +LA +L F+I+ EH+VF V Y +  +IPDVP  ++  ++R+ Y+ ++ L N
Sbjct:   14 FFRDGVRRIDFVLSY--------VDDKDGERKQERRRVFEANLVKVGLELEIEDKSESDDRKTYFVKIHAPWEVLATYADVLKIKVPFKAN--DIPDNSEMPMNWLSTPFRLPEPIMQPEPDFFTAPFDKSKSDFFL-IEDRDKFFLPSTRNRIVYYILSRCSYIRDECGERDKKGIKRLLNNSTYTAAFPLHDSRYWTKSK---DVNCDSDRYNLYKYWAGFFSFFKEQPLNLIRKYYGEKIGLYFAWLGFYTEMLFFAAVVGTLCFVYGVLTYDDNEWSKEICSDEIGGNIVMCPLCD--KKCGFWKLNTTCNSSWQSHLFDNVGTVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCNSRKLNRITQEMEPYLPITSKCARICLSGATVLLWISLIIACIIGVIAYRLAVYAAFASIMKDSPTSNLEVVGPYITPQLATSVTASCINFVIIMILNLMYERVAVWITDMEIPKTHLEYENKLTVKMFLFQFVNYYSSCFYVAFFKGKFVGYPGDYAYMFGKWSKLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALVPWLMNWWAS-RKARSYPESLYSR------WEQDHDLQGFGQLGLFYEYLEMVIQFGFITLFVASFPLAPLLALFNNIIEIRVDAWKLTTQFRRPVAAKAHCIGAWEEILNGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYQPEGEMNMKGYINNSLSVFNISEIPLPNRPEDGENPLWFNSSITTCRYRDYRNPPGHENQYSHTMQFWHILAAKLAFIIIMEHVVFLVKYFVAWMIPDVPSDVKARVKRERYLVQEYLHN 832
[Close]
BLAST of Anoctamin vs. Ensembl Medaka
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:101164640])

HSP 1 Score: 499.975 bits (1286), Expect = 2.785e-162
Identity = 321/842 (38.12%), Postives = 475/842 (56.41%), Query Frame = 2 
Query:  329 YLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXK-MMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGE---IGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEIC--DTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKP--RPEYVALATEKRVNPVTGIEEPYFPVNLRMKRM-LTGXXXX---XXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKAL-------IFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFG----LRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYE--GLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHN----FLLDGYVNFTLAW-------APN-----------NSLSEPCRYRDFRDVNGKLTRF-----YWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLN 2698
            +  DG+RRID+V+ +        VD +   R  E R+ F   L+K+GL  E E +         F+KIH P+ ++  YA+ L  +VP +      P  SE  + +   P  +   +      F TA F   + + +L   + D FF  + R+++   IL+   Y R   GE    GI R+++   Y+AA+PLH+      +     V+  + R  L++YWA +  F+K QP+  IR+YYGEKI +YFAWLG YT  LF A++VG   FVYG+LT      SKEIC  +      MCPLC  +K C +W L+  C  S  ++LFD+ GTVFF+IFM +W   FLE WKR+ A L Y WD VD+EEE ++   RPEY      +++N +T   EPY P+  +  R+ L+G   +    ++   +I  I   +      A  + D+P    + +       +  SV+A+ +N ++IM L L+YE++A  +T  E+ +T  E+E+ LTVK++LF+FVN+YSS FY+AFFKG+F GYPG Y+  FG    LRNE+C  G CL EL  Q+ I+M G Q+  NIQE  +P L+ W+   +K  +    L  +      W +D+ L  +   GLF EYLEM++QFGFIT+FVA+FPLAP  AL NN +EIR+DA KL    RRPVA +A  +G W  ILN +  LS+++NAF++AFTSD IP+ VY Y++       + GY+N +L+         PN           NS    CRYRD+R+  G   ++     +W +LA +L F+I+ EH+VF V Y +  +IPDVP  ++  ++R+ Y+ ++ L N
Sbjct:   58 FFRDGVRRIDFVLSY--------VDDKDGERKQERRRVFEANLVKVGLELEIEDKSESDDRKTYFVKIHAPWEVLATYADVLKIKVPFKAN--DIPDNSEMPMNWLSTPFRLPEPIMQPEPDFFTAPFDKSKSDFFL-IEDRDKFFLPSTRNRIVYYILSRCSYIRDECGERDKKGIKRLLNNSTYTAAFPLHDSRYWTKSK---DVNCDSDRYNLYKYWAGFFSFFKEQPLNLIRKYYGEKIGLYFAWLGFYTEMLFFAAVVGTLCFVYGVLTYDDNEWSKEICSDEIGGNIVMCPLC--DKKCGFWKLNTTCNSSWQSHLFDNVGTVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCNSRKLNRITQEMEPYLPITSKCARICLSGATVLLWISLIIACIIGVIAYRLAVYAAFASIMKDSPTSNLEVVGPYITPQLATSVTASCINFVIIMILNLMYERVAVWITDMEIPKTHLEYENKLTVKMFLFQFVNYYSSCFYVAFFKGKFVGYPGDYAYMFGKWSKLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALVPWLMNWWAS-RKARSYPESLYSR------WEQDHDLQGFGQLGLFYEYLEMVIQFGFITLFVASFPLAPLLALFNNIIEIRVDAWKLTTQFRRPVAAKAHCIGAWEEILNGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYQPEGEMNMKGYINNSLSVFNISEIPLPNRPEDGENPLWFNSSITTCRYRDYRNPPGHENQYSHTMQFWHILAAKLAFIIIMEHVVFLVKYFVAWMIPDVPSDVKARVKRERYLVQEYLHN 876
[Close]
BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000053932.1 (SMESG000053932.1)

HSP 1 Score: 1603.96 bits (4152), Expect = 0.000e+0
Identity = 846/848 (99.76%), Postives = 846/848 (99.76%), Query Frame = 2 
Query:  224 MEKLQLINLKKDKNKESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMTKNEMGSLKRGESLLVKADSKA 2767
            MEKLQLINLKKDKNKES AENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPERRRRITEYRKRF EKLLKMGLSCEEEIEESEKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGVMCIVVMFMIVIIFIIGVIIYRILIAIPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIFVAAFPLAPFFALINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMTKNEMGSLKRGESLLVKADSKA
Sbjct:    1 MEKLQLINLKKDKNKESGAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPERRRRITEYRKRFQEKLLKMGLSCEEEIEESEKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGVMCIVVMFMIVIIFIIGVIIYRILIAIPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIFVAAFPLAPFFALINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMTKNEMGSLKRGESLLVKADSKA 848
[Close]
BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000052528.1 (SMESG000052528.1)

HSP 1 Score: 964.14 bits (2491), Expect = 0.000e+0
Identity = 510/813 (62.73%), Postives = 642/813 (78.97%), Query Frame = 2 
Query:  272 SRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGK-VDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALLNMTK 2707
            +  ENP  +TN +   K  Y +DGIR+IDY+I WE+++   NV+     +   YRKRF E L K+ +  E++ EES+K++I+ +KIHIP++++C YAE +N R PLQ+      + +E++LK   IPN M+  +P  P  + T  FK   L++Y+G  N++TFF+ TQR QVA EILAT VYG++ K EIGIDR+++E IYSAAYPLH+GP +      GK  D  N RQ+L+E WAKWS +YKYQP+++IREYYGEKI +YFAWLG+YT WL PAS++GI VF+YG+LT+     S EIC +N T++MCPLCN + GC YW LSD+CFYS++TY+FDHPGTVFFSIFM+ WAV+FLENWKRKNA L+Y WD + +EEE+++PRPEY AL    ++NPVTG+ EP+FP   +  R LTG+  I +MF++++IFII VIIYR+LIAIPLF NPLLRSKA+IFA+ SAA VNLILIM LG VYEKLAYKLTQWEMHRT+TEF+DHL +KVYLF+FVNFYSSIFYIAFFKGRFNGYPG YSLFFGLRNE+CSNGSCLFELAQQ+AIIMVG QIINN QEIF+PK++TWF++  KGL+ +  L       K W+EDYKLLPYEGLF+EYLEM++QFGFITIFVAAFPLAP FAL+NNW+EIRLDA KLV  TRRP++ERAQD+G W +IL+ IV LS+ISNAFLIAFTS+F+PK +YKY ++  L GYVNFTL+WAPN SL+EPCRYR  RD  G  T  YW+LLA+R  FVI+FEH+VF VA+LIDI+IPD+  +LQ+ MRR+NY+AKQALL   K
Sbjct:   57 NSTENP--ETNFQISDKRCYFSDGIRKIDYIIAWEEEKNGSNVNSIENVKHQNYRKRFEENLKKISVEMEQDDEESDKIIIHCVKIHIPWDLLCHYAEEMNLRAPLQMRNEGRENNTEKLLKLLYIPNIMQLNIPRRPMAYFTCNFKKSNLDRYIGCKNQETFFTATQRQQVAYEILATQVYGKRRKAEIGIDRLLEEGIYSAAYPLHDGPFQQ----CGKNADSLNERQMLYENWAKWSMWYKYQPLDHIREYYGEKIGLYFAWLGMYTVWLLPASIIGILVFIYGLLTINKNVPSNEICQSNQTYRMCPLCNEDIGCPYWYLSDVCFYSKITYMFDHPGTVFFSIFMAFWAVSFLENWKRKNASLAYHWDVIHFEEEEQRPRPEYAALCPSVKMNPVTGLMEPHFPTMRKAFRFLTGICVISIMFVLILIFIIAVIIYRVLIAIPLFQNPLLRSKAIIFANTSAAFVNLILIMCLGRVYEKLAYKLTQWEMHRTQTEFDDHLILKVYLFQFVNFYSSIFYIAFFKGRFNGYPGNYSLFFGLRNEECSNGSCLFELAQQLAIIMVGKQIINNFQEIFVPKILTWFYQCSKGLDKVSNLDENKELIKFWAEDYKLLPYEGLFEEYLEMVLQFGFITIFVAAFPLAPLFALLNNWVEIRLDAKKLVCETRRPISERAQDIGKWSVILDAIVHLSVISNAFLIAFTSEFLPKLIYKYRYDDQLRGYVNFTLSWAPNGSLTEPCRYRALRDEYGSYTIIYWQLLALRFGFVIIFEHVVFSVAHLIDIVIPDISYNLQVRMRRENYLAKQALLEFKK 863
[Close]
BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000006381.1 (SMESG000006381.1)

HSP 1 Score: 863.988 bits (2231), Expect = 0.000e+0
Identity = 454/790 (57.47%), Postives = 591/790 (74.81%), Query Frame = 2 
Query:  326 YYLNDGIRRIDYVIVWEQDRIAINVDPEXXXXXXXXXXXFHEKLLKMGLSCXXXXXXXXKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQL-SGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 2692
            YY NDG  +ID+++ W +         +       YRK+F   L K GL  EE+ +E+ K   ++IKI++P+ IMC +AE L  R PLQ  P  +  +S + L    IPN M  + P  P  F T  FK  ++ ++LG  N+ T+FS+TQRHQV  EIL T +YGR+ KGEIGI RM+D+EIY +AYPLHEGP E     L + +  N RQIL+EYWA++ ++Y+YQP+++IREY+GEKI  YFAW+GLYTAWL PAS++GIFVF+YG+ T      +KEIC  NN+F MCPLC+ + GC+YW L D+C + ++ YLFDHPGT+F+SIFM++WAV FLE WKRKNA L++ WD +DYEEE+E+PR +Y AL +  + NPVTG+ EPYFP   R+ R+LTG++CI++M  +VIIFII VIIYR+LI IP+F NPLLR+ A+ FA+ +AAIVNL+LIM L  VYE +A KLT+WEMHRT+++F++ L  KV+LF+FVNFYSSIFYIAFFKGRF GYPG YS FFGLRNEDC NG CL ELA Q+AIIMVG QII+NIQE+ +PKL TWF+RF KGL   VQ  S  +    ++ ED KL+PYEGL DEYLE+++QFGFITIFVAAFPLAPFFAL+NNW+EIRLDA KLV  T+RPVAERA+D+G WF+IL  I  ++ ISNAFL+AFTS+F+PK  Y+Y  +  LDGY N +L+W+P NS   PCRY  +RD +G L +++W LLA+RL FVIVFEH V G+  L+D+LIPDVP+ L I+++R+ Y+AKQAL
Sbjct:   38 YYFNDGKSKIDFILAWSEKE-------KEPHSKALYRKKFESNLKKAGLELEEDFDETGKF--HYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYGRRRKGEIGIKRMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVMDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTVVIIFIIAVIIYRVLIEIPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVIVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVAAFPLAPFFALLNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD-SLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQAL 817
[Close]
BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000033728.1 (SMESG000033728.1)

HSP 1 Score: 352.058 bits (902), Expect = 2.226e-106
Identity = 218/582 (37.46%), Postives = 336/582 (57.73%), Query Frame = 2 
Query:  836 EIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATE---KRVNPVTGIEEPYFPV-NLRMKRML--TGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFK------KGLN--------NMVQLSGKD--------------VEPKL---WSEDYKLLPY-EGLFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVY--KYSHNFLLDGYVNFTLAW 2461
            + GI ++I E ++ +AY LHE P     DL    +  N R +L+++W      ++ QP+++I+ Y+GEK+A YFAWLG YT WL P SL+GI V +Y I+   +  + KEI    N   MCPL    +GCR+W LSD      +  L D+  TV  ++ MS+WA  FLE WKR+  +L+Y W+  D E EDE  RPE+VAL  +   K+ N ++G EEP+ P    RM  M      + + +   +  +  I +        + +  +  + + + I  + + ++++L++IMSL LVY ++A  LT  E HRT+++++  +T+K+YL EF+N YSSIFYI F +      P   S    ++   C  G CL +L+ Q+A IM+G QII++I+E  LP+LV+   R+K      K +N        + V+++ KD              VEP+L   ++++    P    LF EYLEM++QFGFITIF+ AFPLAP  AL NN  EIR DA K   + RRPVA+R +D+G W  I++++  +++ SNA LIAF + +I K +Y   YS N  L+G+ +F+L++
Sbjct:  271 DFGIAKLISEGVFDSAYILHERPLNEDDDLENVEN--NERNLLYKHWVSMRNIFRLQPLDHIKLYFGEKVAFYFAWLGYYTYWLLPISLLGIIVSLYNIVYTSNDIVVKEIYQGTN-ITMCPLMCSSRGCRFWKLSDAYSRFFLIRLLDNGATVLMAVVMSIWASLFLEMWKRQQVQLAYHWNVHDMEYEDEPARPEFVALIDKNYPKKTNLISGKEEPFIPFWRRRMPVMFFTYSTVLLSIAMALAFLGGIILYKLVSFSLMRMHHSRTISNMSSIITAATGSLLSLVIIMSLTLVYSRVAVWLTDMEHHRTQSQYDSSVTLKLYLLEFINNYSSIFYIGFIQPFTQPIPSFRSSSM-IKPRGCPAGGCLLDLSLQLAFIMIGKQIISHIKEYALPRLVSTVKRYKLKQAEEKLINQSDAEMEADRVEVAIKDKATILDPKCIDTWKVEPELIRCYADNILSDPGPRPLFGEYLEMLIQFGFITIFIPAFPLAPLLALTNNLFEIRSDALKFARALRRPVAQRVKDIGIWVSIMSMVATIAVKSNAILIAFATTYIDKLIYIIGYSENGFLNGFTDFSLSY 848
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BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000033730.1 (SMESG000033730.1)

HSP 1 Score: 328.946 bits (842), Expect = 3.778e-98
Identity = 224/640 (35.00%), Postives = 363/640 (56.72%), Query Frame = 2 
Query:  839 IGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGXXXXXXXXXXXXXXXXXXXXXXXXXXXPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDV-----EPKLWSEDYKLLPYEG--LFDEYLEMIVQFGFITIXXXXXXXXXXXXXINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVY--KYSHNFLLDGYVNFTLAWAPNNSLSEP-----CRYRDFR----DV-NG--KLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALL 2695
            + +  +I E+++ +AY LHE  + +  + L + +  + R  L++ W       + QP+++IR Y+GEKIA YF+WLG YT WLF  SL+G+ + V+ IL   S  I  EI +  N   MCPL    K C++W LSD+ +   +  + D+   V  +  MS+WA  FLE WKR+   L++ W+  D + + E  +PE+VA  T+ + +       P++   +         +   V+  +  +  I +    I   + +  +PL+   + +  SV+ +I++LI+I+ L +VY KLA+ LT  E + T++E++D +T+K+YL EF+N YS +FY  F        PG +     L+   C  G CLF L+ Q+A IM+G Q+I++  E   P L +   ++K    N V+   K++     E     +D  L   E   +F EYLEM++QFGFIT+F+ AFPLAP  AL NN LEIR DA+K + + +RPVA+R +D+GTW  IL+++  L++ SNA LIAFT+ FI + +Y  KYS    L G+ +FTL++  ++  +       CRY DFR    D+ NG   LT  YW +LA ++ FV +FE++V+ +  +I   IP+  E +  E+ ++  ++++ LL
Sbjct:  264 MSLHNLISEQVFESAYCLHE--SFIVQNSLKRDE--SDRVNLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVITVFNILHASSDIIVNEIKEGGN-ITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMVLMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMSNVIISVTGSIISLIVILLLTMVYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIPAFPLAPLLALFNNLLEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRYHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLL 897
The following BLAST results are available for this feature:
BLAST of Anoctamin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ANO70.000e+047.27anoctamin 7 [Source:HGNC Symbol;Acc:HGNC:31677][more]
ANO70.000e+047.48anoctamin 7 [Source:HGNC Symbol;Acc:HGNC:31677][more]
ANO41.244e-16538.72anoctamin 4 [Source:HGNC Symbol;Acc:HGNC:23837][more]
ANO31.578e-16540.78anoctamin 3 [Source:HGNC Symbol;Acc:HGNC:14004][more]
ANO44.906e-16538.72anoctamin 4 [Source:HGNC Symbol;Acc:HGNC:23837][more]
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BLAST of Anoctamin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
anoh-15.851e-6427.34Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286][more]
anoh-19.249e-6427.34Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286][more]
anoh-22.902e-2725.28Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3][more]
anoh-23.026e-2725.28Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3][more]
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BLAST of Anoctamin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
subdued1.462e-17040.07gene:FBgn0038721 transcript:FBtr0083806[more]
subdued1.462e-17040.07gene:FBgn0038721 transcript:FBtr0334921[more]
subdued7.651e-16939.91gene:FBgn0038721 transcript:FBtr0083805[more]
subdued7.587e-16738.86gene:FBgn0038721 transcript:FBtr0334922[more]
subdued6.207e-16538.37gene:FBgn0038721 transcript:FBtr0302492[more]
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BLAST of Anoctamin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ano110.000e+050.42anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
ano110.000e+050.42anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
ano110.000e+057.03anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
si:dkey-83h2.50.000e+049.44si:dkey-83h2.5 [Source:ZFIN;Acc:ZDB-GENE-131125-81... [more]
ano31.888e-17239.86anoctamin 3 [Source:ZFIN;Acc:ZDB-GENE-111031-3][more]
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BLAST of Anoctamin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ANO42.071e-16741.18major histocompatibility complex class I-related g... [more]
ANO45.911e-16740.00major histocompatibility complex class I-related g... [more]
ANO57.116e-16539.71anoctamin 5 [Source:NCBI gene;Acc:100489787][more]
ANO51.004e-16439.78anoctamin 5 [Source:NCBI gene;Acc:100489787][more]
ANO51.779e-16439.78anoctamin 5 [Source:NCBI gene;Acc:100489787][more]
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BLAST of Anoctamin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ano70.000e+049.18anoctamin 7 [Source:MGI Symbol;Acc:MGI:3052714][more]
Ano70.000e+049.18anoctamin 7 [Source:MGI Symbol;Acc:MGI:3052714][more]
Ano44.518e-16738.69anoctamin 4 [Source:MGI Symbol;Acc:MGI:2443344][more]
Ano44.518e-16738.69anoctamin 4 [Source:MGI Symbol;Acc:MGI:2443344][more]
Ano41.446e-16638.69anoctamin 4 [Source:MGI Symbol;Acc:MGI:2443344][more]
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BLAST of Anoctamin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q14AT5|ANO7_MOUSE0.000e+049.18Anoctamin-7 OS=Mus musculus OX=10090 GN=Ano7 PE=1 ... [more]
sp|Q6IFT6|ANO7_RAT0.000e+048.60Anoctamin-7 OS=Rattus norvegicus OX=10116 GN=Ano7 ... [more]
sp|Q6IWH7|ANO7_HUMAN0.000e+047.27Anoctamin-7 OS=Homo sapiens OX=9606 GN=ANO7 PE=1 S... [more]
sp|A6QLE6|ANO4_BOVIN3.911e-16638.95Anoctamin-4 OS=Bos taurus OX=9913 GN=ANO4 PE=2 SV=... [more]
sp|Q8C5H1|ANO4_MOUSE1.011e-16538.69Anoctamin-4 OS=Mus musculus OX=10090 GN=Ano4 PE=1 ... [more]
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BLAST of Anoctamin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267H1A60.000e+061.20Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX1... [more]
A0A267FA310.000e+061.20Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX1... [more]
A0A267GKF10.000e+061.20Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX1... [more]
A0A267F3V40.000e+061.26Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX1... [more]
A0A4Z2DG130.000e+055.84Anoctamin OS=Schistosoma japonicum OX=6182 GN=EWB0... [more]
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BLAST of Anoctamin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ano110.000e+052.20anoctamin-7 [Source:NCBI gene;Acc:103029593][more]
ano110.000e+052.11anoctamin-7 [Source:NCBI gene;Acc:103029593][more]
si:dkey-83h2.50.000e+048.50anoctamin-7-like [Source:NCBI gene;Acc:103022406][more]
si:dkey-83h2.50.000e+049.87anoctamin-7-like [Source:NCBI gene;Acc:103022406][more]
si:dkey-83h2.50.000e+049.29anoctamin-7-like [Source:NCBI gene;Acc:103022406][more]
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BLAST of Anoctamin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ano110.000e+050.13anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
ano111.602e-13858.90anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
ano113.621e-13858.58anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
ano111.033e-13356.61anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
ENSPMAT00000000399.13.294e-11839.20pep scaffold:Pmarinus_7.0:GL477564:2673:43187:-1 g... [more]
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BLAST of Anoctamin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Anoctamin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO498550.000e+051.36Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REV0][more]
EDO498540.000e+053.64Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REU8][more]
EDO480482.228e-15837.91Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU7][more]
EDO480503.500e-15338.38Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU9][more]
EDO483075.236e-14937.44Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RJQ8][more]
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BLAST of Anoctamin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-83h2.50.000e+048.05anoctamin 7 [Source:NCBI gene;Acc:101162585][more]
ano36.348e-17741.65anoctamin 3 [Source:NCBI gene;Acc:101164148][more]
ano35.389e-16439.70anoctamin 3 [Source:NCBI gene;Acc:101164148][more]
ano5a8.367e-16338.12anoctamin 5 [Source:NCBI gene;Acc:101164640][more]
ano5a2.785e-16238.12anoctamin 5 [Source:NCBI gene;Acc:101164640][more]
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BLAST of Anoctamin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053932.10.000e+099.76SMESG000053932.1[more]
SMESG000052528.10.000e+062.73SMESG000052528.1[more]
SMESG000006381.10.000e+057.47SMESG000006381.1[more]
SMESG000033728.12.226e-10637.46SMESG000033728.1[more]
SMESG000033730.13.778e-9835.00SMESG000033730.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006906 ID=SMED30006906|Name=Anoctamin|organism=Schmidtea mediterranea sexual|type=transcript|length=2834bp
CTCTCAAGTCATATATTGATAAGCTAGTGAGTGAACCCTGTGAGAGCTAC
CTTGGCCAGCCACAACGCATAATGAATGTGCGCATGCCACACAGCAATAA
TTCTGCCATTGTAGCACTGTCGAATATAGCACTATTGATAATGTTTATTG
ATTGTTATCATTTTTAGAATATTTTATTTTAGAATTAAGCCATAGAATTA
CTTCACCAAAATTCGACTGTCAGATGGAAAAATTGCAACTGATAAATTTG
AAAAAAGATAAAAATAAAGAATCTCGAGCGGAAAATCCTCTGTTAAAAAC
AAATACAAAAGAATTATGTAAATATTATTATCTTAACGATGGAATACGAA
GAATTGATTATGTCATTGTTTGGGAACAAGATCGAATAGCAATAAATGTT
GATCCAGAGCGTCGAAGAAGAATTACTGAATACCGAAAACGATTCCATGA
GAAATTACTTAAGATGGGATTATCCTGTGAAGAAGAAATCGAAGAAAGTG
AAAAGATGATGATAAATTTTATTAAAATTCATATTCCCTTTAATATAATG
TGTATATATGCAGAGGCTCTCAATTTCAGAGTTCCTCTACAAATTGGCCC
GCCGCATACTCCGCATTTTTCTGAAAGAGTGCTGAAATTTTTTCTGATTC
CTAATTTTATGAAAAATGAATTGCCTTATTCTCCAGATTGCTTTGCTACG
GCTGCATTCAAGACTGACCAACTTGAAAAATATTTAGGATATACAAACGA
GGATACGTTTTTCAGTACTACCCAACGGCATCAGGTTGCTCGGGAAATTC
TAGCAACGACAGTTTATGGTCGCCAGACTAAGGGTGAAATTGGAATAGAC
CGGATGATTGATGAAGAGATTTATTCTGCTGCTTATCCATTGCATGAAGG
ACCCGCTGAAGTACCAACAGATTTATTGGGCAAAGTAGATTTGTGGAATC
GCCGACAAATTCTATTTGAATATTGGGCAAAATGGTCAAAATTTTATAAA
TACCAACCGATAGAAAATATTCGAGAATATTATGGAGAAAAGATCGCGAT
TTACTTTGCTTGGTTGGGCCTCTACACAGCCTGGTTGTTTCCAGCCTCAC
TTGTTGGTATCTTTGTGTTCGTTTATGGAATTTTGACAATGAAATCGTAT
ACAATCAGCAAAGAAATATGTGACACTAACAACACCTTCAAAATGTGTCC
ATTGTGTAATTACGAAAAAGGATGTCGATATTGGAATTTGTCGGATATTT
GCTTCTATTCTCAAATGACATACTTATTCGATCATCCGGGAACAGTATTT
TTCTCGATTTTCATGTCGGTTTGGGCTGTGGCTTTTCTCGAAAATTGGAA
ACGAAAAAATGCTGAGTTGTCTTATAGGTGGGACACGGTGGACTATGAAG
AAGAGGATGAGAAACCTCGGCCGGAATATGTGGCGTTGGCAACGGAAAAA
CGAGTGAACCCAGTGACGGGAATTGAAGAACCTTATTTCCCAGTCAATTT
GAGAATGAAAAGAATGCTCACTGGTGTCATGTGTATAGTCGTTATGTTTA
TGATTGTTATAATATTTATTATTGGGGTGATTATCTATCGGATTTTGATA
GCAATACCATTATTCGACAATCCATTATTGCGCTCGAAAGCACTTATATT
TGCCAGTGTTTCGGCTGCGATTGTCAATTTGATTTTAATCATGTCTCTTG
GACTGGTTTATGAAAAACTGGCCTACAAACTGACTCAATGGGAAATGCAT
CGTACTGAAACAGAATTTGAAGATCATCTTACTGTTAAGGTTTATTTGTT
TGAATTCGTCAATTTCTATTCGTCAATATTTTATATTGCGTTTTTCAAAG
GCAGATTCAATGGATACCCTGGAAAATATTCATTATTTTTTGGTTTGCGG
AACGAGGATTGTAGTAACGGAAGTTGTTTGTTTGAATTAGCCCAACAAAT
GGCCATTATAATGGTTGGTAACCAAATTATTAATAATATACAGGAAATAT
TTTTACCGAAATTGGTTACTTGGTTCCATAGATTTAAAAAAGGTCTAAAT
AATATGGTTCAACTTTCAGGTAAAGATGTCGAACCTAAACTTTGGTCGGA
GGACTATAAATTATTGCCTTATGAAGGATTGTTTGACGAATATTTGGAAA
TGATCGTTCAATTCGGTTTCATTACTATTTTTGTGGCGGCCTTTCCACTC
GCTCCATTTTTTGCTTTGATTAACAACTGGTTAGAGATACGTTTGGATGC
TAGCAAATTAGTCCTAAGCACTCGACGTCCTGTGGCAGAAAGGGCCCAAG
ACATGGGAACTTGGTTCATAATTTTAAATTTGATAGTGAAATTGTCAATA
ATCTCAAATGCATTCCTTATAGCTTTTACTTCAGACTTTATCCCGAAGCA
GGTGTACAAGTATTCTCATAATTTCCTATTAGATGGCTATGTAAATTTCA
CATTAGCCTGGGCTCCTAACAATTCATTGTCAGAACCTTGCCGGTATCGA
GATTTCCGGGATGTCAATGGAAAGCTAACAAGATTTTACTGGCGTCTTTT
GGCTATTCGGCTGACGTTTGTAATCGTTTTCGAGCATATAGTTTTTGGAG
TTGCTTATTTGATAGACATTTTGATTCCTGACGTTCCGGAAAGCCTTCAA
ATTGAAATGAGGAGAAAGAACTACATGGCAAAACAGGCGCTACTGAATAT
GACAAAGAATGAAATGGGAAGTCTGAAAAGAGGCGAGAGCTTACTTGTAA
AAGCCGATTCTAAAGCTTGATATCTAAAATTATTAGTTGCTTTTTATTGT
AATTGAAAATAAATTGTATTATTGTTAGATCGGA
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protein sequence of SMED30006906-orf-1

>SMED30006906-orf-1 ID=SMED30006906-orf-1|Name=SMED30006906-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=849bp
MEKLQLINLKKDKNKESRAENPLLKTNTKELCKYYYLNDGIRRIDYVIVW
EQDRIAINVDPERRRRITEYRKRFHEKLLKMGLSCEEEIEESEKMMINFI
KIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNEL
PYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGR
QTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEY
WAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFV
YGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTY
LFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRP
EYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGVMCIVVMFMIVIIFII
GVIIYRILIAIPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLA
YKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPG
KYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTW
FHRFKKGLNNMVQLSGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFI
TIFVAAFPLAPFFALINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFII
LNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNN
SLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDIL
IPDVPESLQIEMRRKNYMAKQALLNMTKNEMGSLKRGESLLVKADSKA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0061588calcium activated phospholipid scrambling
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR031296Anoctamin-7
IPR007632Anoctamin
IPR032394Anoct_dimer
Vocabulary: molecular function
TermDefinition
GO:0046983protein dimerization activity
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR032394Anoctamin, dimerisation domainPFAMPF16178Anoct_dimercoord: 37..263
e-value: 9.9E-59
score: 198.8
IPR007632AnoctaminPFAMPF04547Anoctamincoord: 266..815
e-value: 7.5E-157
score: 522.7
IPR007632AnoctaminPANTHERPTHR12308NGEP-RELATEDcoord: 13..825
IPR031296Anoctamin-7PANTHERPTHR12308:SF22ANOCTAMIN-7coord: 13..825
NoneNo IPR availableTMHMMTMhelixcoord: 697..719
NoneNo IPR availableTMHMMTMhelixcoord: 350..372
NoneNo IPR availableTMHMMTMhelixcoord: 644..666
NoneNo IPR availableTMHMMTMhelixcoord: 437..459
NoneNo IPR availableTMHMMTMhelixcoord: 734..753
NoneNo IPR availableTMHMMTMhelixcoord: 775..797
NoneNo IPR availableTMHMMTMhelixcoord: 277..299
NoneNo IPR availableTMHMMTMhelixcoord: 474..496
NoneNo IPR availableTMHMMTMhelixcoord: 519..541