Protein dpy-30-like

Overview


Name	Protein dpy-30-like
Smed ID	SMED30006884
Length (bp)	423

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein dpy-30-like (SMED30006884) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein dpy-30-like (SMED30006884) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein dpy-30-like (SMED30006884) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein dpy-30-like (SMED30006884) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30006884

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 15

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30006884	SMESG000008786.1	SmedASXL_006566	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30006884	SMESG000008786.1	dd_Smed_v4_9103_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30006884	SMESG000008786.1	dd_Smed_v4_9103_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30006884	SMESG000008786.1	dd_Smed_v4_9103_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30006884	SMESG000008786.1	dd_Smed_v4_9103_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30006884	SMESG000008786.1	dd_Smed_v4_9103_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30006884	SMESG000008786.1	dd_Smed_v4_9103_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30006884	SMESG000009146.1 SMESG000008786.1 SMESG000008785.1	Contig43862	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30006884	SMESG000009146.1 SMESG000008786.1 SMESG000008785.1	Contig43862	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
head region	SMED30006884	SMESG000008786.1	dd_Smed_v6_9103_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30006884	SMESG000008786.1	dd_Smed_v4_9103_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
gut	SMED30006884	SMESG000008786.1	KC262338	smed_ncbi_20200123	PMID:23235145 Hubert et al., 2013
neoblast	SMED30006884	SMESG000008786.1	KC262338	smed_ncbi_20200123	PMID:23235145 Hubert et al., 2013
parenchyma	SMED30006884	SMESG000008786.1	KC262338	smed_ncbi_20200123	PMID:23235145 Hubert et al., 2013
parenchymal cell	SMED30006884	SMESG000008786.1	KC262338	smed_ncbi_20200123	PMID:23235145 Hubert et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of Protein dpy-30-like vs. Ensembl Human
Match: DPY30 (dpy-30 histone methyltransferase complex regulatory subunit [Source:HGNC Symbol;Acc:HGNC:24590])

HSP 1 Score: 81.2629 bits (199), Expect = 2.068e-20
Identity = 36/72 (50.00%), Postives = 54/72 (75.00%), Query Frame = 1

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            N+E+I+  E     K     +++QSLP+R YL++TV+PIL+QG+  L KERPPNPIE++A++LLKNK+ +E 
Sbjct:   26 NVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFED 97

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Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            N+E+I+  E     K     +++QSLP+R YL++TV+PIL+QG+  L KERPPNPIE++A++LLKNK+ +E 
Sbjct:   26 NVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFED 97

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BLAST of Protein dpy-30-like vs. Ensembl Human
Match: AK7 (adenylate kinase 7 [Source:HGNC Symbol;Acc:HGNC:20091])

HSP 1 Score: 50.0618 bits (118), Expect = 2.661e-7
Identity = 22/46 (47.83%), Postives = 31/46 (67.39%), Query Frame = 1

Query:  217 LEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKN 354
            LE QS+P R YL   V+P LIQG+N     RP +P++++A +L KN
Sbjct:  673 LEAQSIPLRNYLMTYVMPTLIQGLNECCNVRPEDPVDFLAEYLFKN 718

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BLAST of Protein dpy-30-like vs. Ensembl Celegans
Match: dpy-30 (Dosage compensation protein dpy-30 [Source:UniProtKB/Swiss-Prot;Acc:Q10661])

HSP 1 Score: 63.1586 bits (152), Expect = 1.454e-13
Identity = 25/48 (52.08%), Postives = 37/48 (77.08%), Query Frame = 1

Query:  229 SLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            ++P+R YL+ TV+PIL+QG+  L K+RP NPIE++A FLL+ K  Y +
Sbjct:   67 TVPTRQYLDSTVVPILLQGLGALAKDRPENPIEFLANFLLREKDRYNA 114

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Query:  229 SLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            ++P+R YL+ TV+PIL+QG+  L K+RP NPIE++A FLL+ K  Y +
Sbjct:   67 TVPTRQYLDSTVVPILLQGLGALAKDRPENPIEFLANFLLREKDRYNA 114

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BLAST of Protein dpy-30-like vs. Ensembl Fly
Match: Dpy-30L2 (gene:FBgn0035491 transcript:FBtr0073281)

HSP 1 Score: 59.3066 bits (142), Expect = 3.190e-12
Identity = 27/67 (40.30%), Postives = 43/67 (64.18%), Query Frame = 1

Query:  160 IEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKS 360
            ++ I A    +K +P     +  S+P R YL++TV PIL+ G+  L ++RP +PI Y+A +LLKNK+
Sbjct:   27 VDGIDAFAACQKPRP-----DTSSMPVRQYLDQTVAPILLHGLQALARDRPSDPISYLATYLLKNKN 88

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BLAST of Protein dpy-30-like vs. Ensembl Fly
Match: Dpy-30L2 (gene:FBgn0035491 transcript:FBtr0332981)

HSP 1 Score: 59.3066 bits (142), Expect = 3.190e-12
Identity = 27/67 (40.30%), Postives = 43/67 (64.18%), Query Frame = 1

Query:  160 IEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKS 360
            ++ I A    +K +P     +  S+P R YL++TV PIL+ G+  L ++RP +PI Y+A +LLKNK+
Sbjct:   27 VDGIDAFAACQKPRP-----DTSSMPVRQYLDQTVAPILLHGLQALARDRPSDPISYLATYLLKNKN 88

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BLAST of Protein dpy-30-like vs. Ensembl Fly
Match: Dpy-30L1 (gene:FBgn0032293 transcript:FBtr0080112)

HSP 1 Score: 58.5362 bits (140), Expect = 1.543e-11
Identity = 22/55 (40.00%), Postives = 40/55 (72.73%), Query Frame = 1

Query:  205 KLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYE 369
            K  + E  ++P+R YL++TV P+L+ GM  L +ERP +PI+++A++LLK+ +  +
Sbjct:   67 KKPSSETNNMPTRQYLDQTVAPVLLHGMQALARERPTDPIQFLASYLLKHSNGCD 121

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BLAST of Protein dpy-30-like vs. Ensembl Fly
Match: CG33060 (gene:FBgn0053060 transcript:FBtr0305307)

HSP 1 Score: 43.1282 bits (100), Expect = 7.590e-6
Identity = 18/43 (41.86%), Postives = 29/43 (67.44%), Query Frame = 1

Query:  241 RLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYE 369
            R++LE+ V+PIL++GM  L +E P +PI Y+  F L +K   +
Sbjct:   71 RIFLEQEVVPILMEGMLGLAREMPRDPIGYLQKFWLDDKHKCD 113

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BLAST of Protein dpy-30-like vs. Ensembl Zebrafish
Match: dpy30 (dpy-30 histone methyltransferase complex regulatory subunit [Source:ZFIN;Acc:ZDB-GENE-040718-136])

HSP 1 Score: 80.8777 bits (198), Expect = 2.583e-20
Identity = 39/73 (53.42%), Postives = 56/73 (76.71%), Query Frame = 1

Query:  157 NIEKIIAIEN--QRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYE 369
            NI++I   E   ++  K K+    +Q+LP+R YL++TV+PIL+QG++ L KERPPNPIE++AAFLLKNKS +E
Sbjct:   31 NIQRIAENEKTAEKVGKQKVDPQTLQTLPTRAYLDQTVVPILLQGLSVLAKERPPNPIEFLAAFLLKNKSQFE 103

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BLAST of Protein dpy-30-like vs. Ensembl Zebrafish
Match: ak7b (adenylate kinase 7b [Source:ZFIN;Acc:ZDB-GENE-050309-170])

HSP 1 Score: 46.595 bits (109), Expect = 2.232e-6
Identity = 22/52 (42.31%), Postives = 34/52 (65.38%), Query Frame = 1

Query:  199 KPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKN 354
            + +L  LE QS P R YL + V+P L QG+    + RP +PI+++A +LL+N
Sbjct:  644 RQELDLLESQSEPLRDYLMQDVMPTLTQGLIECCRLRPDDPIDFLAEYLLQN 695

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BLAST of Protein dpy-30-like vs. Ensembl Zebrafish
Match: dpy30 (dpy-30 histone methyltransferase complex regulatory subunit [Source:ZFIN;Acc:ZDB-GENE-040718-136])

HSP 1 Score: 43.1282 bits (100), Expect = 5.750e-6
Identity = 23/54 (42.59%), Postives = 37/54 (68.52%), Query Frame = 1

Query:  157 NIEKIIAIENQRKL----KPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKE 306
            NI++I   EN++      K K+    +Q+LP+R YL++TV+PIL+QG++ L KE
Sbjct:   31 NIQRIA--ENEKTAEKVGKQKVDPQTLQTLPTRAYLDQTVVPILLQGLSVLAKE 82

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BLAST of Protein dpy-30-like vs. Ensembl Xenopus
Match: gtf3c6 (general transcription factor IIIC subunit 6 [Source:Xenbase;Acc:XB-GENE-5805128])

HSP 1 Score: 83.5741 bits (205), Expect = 2.439e-21
Identity = 37/71 (52.11%), Postives = 54/71 (76.06%), Query Frame = 1

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYE 369
            N+E+I+  E     K     +++Q LP+R YL++TV+PIL+QG++ L KERPPNPIEY+AA+LLKNK+ +E
Sbjct:   26 NVERIVENEKTSTEKISKQKVDLQGLPTRAYLDQTVVPILLQGLSVLAKERPPNPIEYLAAYLLKNKTQFE 96

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BLAST of Protein dpy-30-like vs. Ensembl Xenopus
Match: sesn1 (sestrin 1 [Source:Xenbase;Acc:XB-GENE-491636])

HSP 1 Score: 50.0618 bits (118), Expect = 2.272e-7
Identity = 20/46 (43.48%), Postives = 33/46 (71.74%), Query Frame = 1

Query:  217 LEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKN 354
            LE QS+P R YL + V+P L+QG+N   K RP +P++++A ++ +N
Sbjct:  660 LEAQSVPLRNYLMKNVMPTLMQGLNECCKIRPHDPVDFLAEYIFRN 705

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BLAST of Protein dpy-30-like vs. Ensembl Xenopus
Match: sesn1 (sestrin 1 [Source:Xenbase;Acc:XB-GENE-491636])

HSP 1 Score: 50.0618 bits (118), Expect = 2.316e-7
Identity = 20/46 (43.48%), Postives = 33/46 (71.74%), Query Frame = 1

Query:  217 LEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKN 354
            LE QS+P R YL + V+P L+QG+N   K RP +P++++A ++ +N
Sbjct:  660 LEAQSVPLRNYLMKNVMPTLMQGLNECCKIRPHDPVDFLAEYIFRN 705

[Close]

BLAST of Protein dpy-30-like vs. Ensembl Xenopus
Match: sesn1 (sestrin 1 [Source:Xenbase;Acc:XB-GENE-491636])

HSP 1 Score: 50.0618 bits (118), Expect = 2.339e-7
Identity = 20/46 (43.48%), Postives = 33/46 (71.74%), Query Frame = 1

Query:  217 LEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKN 354
            LE QS+P R YL + V+P L+QG+N   K RP +P++++A ++ +N
Sbjct:  660 LEAQSVPLRNYLMKNVMPTLMQGLNECCKIRPHDPVDFLAEYIFRN 705

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BLAST of Protein dpy-30-like vs. Ensembl Xenopus
Match: sesn1 (sestrin 1 [Source:Xenbase;Acc:XB-GENE-491636])

HSP 1 Score: 49.6766 bits (117), Expect = 2.644e-7
Identity = 20/46 (43.48%), Postives = 33/46 (71.74%), Query Frame = 1

Query:  217 LEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKN 354
            LE QS+P R YL + V+P L+QG+N   K RP +P++++A ++ +N
Sbjct:  647 LEAQSVPLRNYLMKNVMPTLMQGLNECCKIRPHDPVDFLAEYIFRN 692

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BLAST of Protein dpy-30-like vs. Ensembl Mouse
Match: Dpy30 (dpy-30, histone methyltransferase complex regulatory subunit [Source:MGI Symbol;Acc:MGI:1913560])

HSP 1 Score: 79.337 bits (194), Expect = 7.138e-20
Identity = 35/72 (48.61%), Postives = 54/72 (75.00%), Query Frame = 1

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            ++E+I+  E     K     +++QSLP+R YL++TV+PIL+QG+  L KERPPNPIE++A++LLKNK+ +E 
Sbjct:   26 SVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFED 97

[Close]

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            ++E+I+  E     K     +++QSLP+R YL++TV+PIL+QG+  L KERPPNPIE++A++LLKNK+ +E 
Sbjct:   26 SVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFED 97

[Close]

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            ++E+I+  E     K     +++QSLP+R YL++TV+PIL+QG+  L KERPPNPIE++A++LLKNK+ +E 
Sbjct:   26 SVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFED 97

[Close]

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            ++E+I+  E     K     +++QSLP+R YL++TV+PIL+QG+  L KERPPNPIE++A++LLKNK+ +E 
Sbjct:   26 SVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFED 97

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BLAST of Protein dpy-30-like vs. Ensembl Mouse
Match: Ak7 (adenylate kinase 7 [Source:MGI Symbol;Acc:MGI:1926051])

HSP 1 Score: 51.9878 bits (123), Expect = 3.236e-8
Identity = 22/46 (47.83%), Postives = 33/46 (71.74%), Query Frame = 1

Query:  217 LEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKN 354
            LE+QS+P R YL   V+P L+QG+N   K RP +P++++A +L KN
Sbjct:  673 LEVQSVPLRNYLMTYVMPTLMQGLNECCKVRPEDPVDFLAEYLFKN 718

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BLAST of Protein dpy-30-like vs. UniProt/SwissProt
Match: sp|Q9C005|DPY30_HUMAN (Protein dpy-30 homolog OS=Homo sapiens OX=9606 GN=DPY30 PE=1 SV=1)

HSP 1 Score: 81.2629 bits (199), Expect = 9.930e-20
Identity = 36/72 (50.00%), Postives = 54/72 (75.00%), Query Frame = 1

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            N+E+I+  E     K     +++QSLP+R YL++TV+PIL+QG+  L KERPPNPIE++A++LLKNK+ +E 
Sbjct:   26 NVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFED 97

[Close]

BLAST of Protein dpy-30-like vs. UniProt/SwissProt
Match: sp|Q2NKU6|DPY30_BOVIN (Protein dpy-30 homolog OS=Bos taurus OX=9913 GN=DPY30 PE=3 SV=1)

HSP 1 Score: 81.2629 bits (199), Expect = 9.930e-20
Identity = 36/72 (50.00%), Postives = 54/72 (75.00%), Query Frame = 1

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            N+E+I+  E     K     +++QSLP+R YL++TV+PIL+QG+  L KERPPNPIE++A++LLKNK+ +E 
Sbjct:   26 NVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFED 97

[Close]

BLAST of Protein dpy-30-like vs. UniProt/SwissProt
Match: sp|Q99LT0|DPY30_MOUSE (Protein dpy-30 homolog OS=Mus musculus OX=10090 GN=Dpy30 PE=1 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 4.993e-19
Identity = 35/72 (48.61%), Postives = 54/72 (75.00%), Query Frame = 1

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            ++E+I+  E     K     +++QSLP+R YL++TV+PIL+QG+  L KERPPNPIE++A++LLKNK+ +E 
Sbjct:   26 SVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFED 97

[Close]

BLAST of Protein dpy-30-like vs. UniProt/SwissProt
Match: sp|Q8K3E7|DPY30_RAT (Protein dpy-30 homolog OS=Rattus norvegicus OX=10116 GN=Dpy30 PE=1 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 2.325e-18
Identity = 34/72 (47.22%), Postives = 53/72 (73.61%), Query Frame = 1

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            ++E+I+  E     K     +++QSLP+R YL++TV+PIL+QG+  L KERPPNP E++A++LLKNK+ +E 
Sbjct:   26 SVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPTEFLASYLLKNKAQFED 97

[Close]

BLAST of Protein dpy-30-like vs. UniProt/SwissProt
Match: sp|Q10661|DPY30_CAEEL (Dosage compensation protein dpy-30 OS=Caenorhabditis elegans OX=6239 GN=dpy-30 PE=1 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 1.849e-12
Identity = 25/48 (52.08%), Postives = 37/48 (77.08%), Query Frame = 1

Query:  229 SLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            ++P+R YL+ TV+PIL+QG+  L K+RP NPIE++A FLL+ K  Y +
Sbjct:   67 TVPTRQYLDSTVVPILLQGLGALAKDRPENPIEFLANFLLREKDRYNA 114

[Close]

BLAST of Protein dpy-30-like vs. TrEMBL
Match: L0H755 (Dpy30-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 1.305e-48
Identity = 83/84 (98.81%), Postives = 83/84 (98.81%), Query Frame = 1

Query:  124 LPTSVLESKILNIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYESM 375
            LPTS LESKILNIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYESM
Sbjct:    4 LPTSELESKILNIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYESM 87

[Close]

BLAST of Protein dpy-30-like vs. TrEMBL
Match: L0H9N7 (Dpy30-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 128.257 bits (321), Expect = 4.658e-36
Identity = 66/70 (94.29%), Postives = 68/70 (97.14%), Query Frame = 1

Query:  124 LPTSVLESKILNIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYM 333
            LPTSVLE KI +IEKII+IENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYM
Sbjct:    4 LPTSVLEFKIFDIEKIISIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYM 73

[Close]

BLAST of Protein dpy-30-like vs. TrEMBL
Match: C3XZ39 (Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_202721 PE=4 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 4.861e-21
Identity = 41/71 (57.75%), Postives = 57/71 (80.28%), Query Frame = 1

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYE 369
            N++K+I  E +   KP    +E+QSLP+R YL++TV+PIL+QG++ L KERPPNPIEY+AA+LLKNKS +E
Sbjct:   29 NVQKMITAEKEAAEKPIKQKVELQSLPTRAYLDQTVVPILLQGLSTLAKERPPNPIEYLAAYLLKNKSKFE 99

[Close]

BLAST of Protein dpy-30-like vs. TrEMBL
Match: R7VAY8 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_155367 PE=4 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 1.618e-20
Identity = 44/74 (59.46%), Postives = 58/74 (78.38%), Query Frame = 1

Query:  157 NIEKIIAIENQRKLKP---KLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYE 369
            NI+K+IA E +    P   K   +E+QSLP+R YL++TV+PIL+QGM+ L KERPPNPIEY+AA+LLKNKS +E
Sbjct:   31 NIQKVIAHEKESLEAPSSAKRPKVELQSLPTRAYLDQTVVPILLQGMSVLSKERPPNPIEYLAAYLLKNKSQFE 104

[Close]

BLAST of Protein dpy-30-like vs. TrEMBL
Match: A7RP67 (Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g239717 PE=4 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 4.700e-20
Identity = 40/71 (56.34%), Postives = 55/71 (77.46%), Query Frame = 1

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYE 369
            N++KII  E +   KP    +++QSLP+R YL++TV+PIL+QG+  L KERPPN I+Y+AA+LLKNKS YE
Sbjct:   41 NLQKIIEKEKEEADKPTKAKVDLQSLPTRAYLDQTVVPILLQGLATLAKERPPNAIDYLAAYLLKNKSQYE 111

[Close]

BLAST of Protein dpy-30-like vs. Ensembl Cavefish
Match: dpy30 (dpy-30 histone methyltransferase complex regulatory subunit [Source:NCBI gene;Acc:103036540])

HSP 1 Score: 82.8037 bits (203), Expect = 3.622e-21
Identity = 38/75 (50.67%), Postives = 55/75 (73.33%), Query Frame = 1

Query:  157 NIEKIIAIEN---QRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            NI++I+  E     +  K K+    +Q+LP+R YL++TV+PIL+QG++ L KERPPNPIE++A FLLKNKS +E 
Sbjct:   30 NIQRIVDSEKTNADKSTKQKVDLQTLQTLPTRAYLDQTVVPILLQGLSVLAKERPPNPIEFLATFLLKNKSQFED 104

[Close]

BLAST of Protein dpy-30-like vs. Ensembl Cavefish
Match: ak7b (adenylate kinase 7 [Source:NCBI gene;Acc:103041221])

HSP 1 Score: 46.2098 bits (108), Expect = 3.059e-6
Identity = 20/46 (43.48%), Postives = 31/46 (67.39%), Query Frame = 1

Query:  217 LEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKN 354
            LE +S+P R YL   V+P L QG+    + RP +P++++A +LLKN
Sbjct:  656 LEAESVPLRQYLMRDVMPTLTQGLIECCRIRPEDPVDFLAEYLLKN 701

[Close]

BLAST of Protein dpy-30-like vs. Ensembl Nematostella
Match: EDO46806 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP67])

HSP 1 Score: 88.9669 bits (219), Expect = 6.500e-24
Identity = 40/71 (56.34%), Postives = 55/71 (77.46%), Query Frame = 1

Query:  157 NIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYE 369
            N++KII  E +   KP    +++QSLP+R YL++TV+PIL+QG+  L KERPPN I+Y+AA+LLKNKS YE
Sbjct:   41 NLQKIIEKEKEEADKPTKAKVDLQSLPTRAYLDQTVVPILLQGLATLAKERPPNAIDYLAAYLLKNKSQYE 111

[Close]

BLAST of Protein dpy-30-like vs. Ensembl Nematostella
Match: EDO36546 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIC3])

HSP 1 Score: 44.669 bits (104), Expect = 3.298e-6
Identity = 21/46 (45.65%), Postives = 31/46 (67.39%), Query Frame = 1

Query:  217 LEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKN 354
            LE QS+P R YL + V+P L QG+    K RP +PI+++A +L +N
Sbjct:  657 LENQSIPLRNYLMKHVMPTLTQGLIEACKVRPDDPIDFVAEYLFQN 702

[Close]

BLAST of Protein dpy-30-like vs. Ensembl Medaka
Match: dpy30 (dpy-30 histone methyltransferase complex regulatory subunit [Source:ZFIN;Acc:ZDB-GENE-040718-136])

HSP 1 Score: 78.5666 bits (192), Expect = 8.589e-20
Identity = 34/68 (50.00%), Postives = 52/68 (76.47%), Query Frame = 1

Query:  175 AIENQRKLKPKLTT--LEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYES 372
            A++  +    KL+   +++Q+LP+R YL++TV+PIL+QG++ L KERPPNPIE++A FLLKNK  +E 
Sbjct:   19 AVDGDKAGADKLSKQKVDLQALPTRAYLDQTVVPILLQGLSVLAKERPPNPIEFLATFLLKNKVQFED 86

[Close]

BLAST of Protein dpy-30-like vs. Planmine SMEST
Match: SMESG000008786.1 (SMESG000008786.1)

HSP 1 Score: 185.652 bits (470), Expect = 7.598e-62
Identity = 111/112 (99.11%), Postives = 111/112 (99.11%), Query Frame = 1

Query:   40 MNESNNIDESHLFSSXXXXXXXXXXXXXLPTSVLESKILNIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYESM 375
            MNESNNIDESHLFSSENNEEKERTEEIELPTS LESKILNIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYESM
Sbjct:    1 MNESNNIDESHLFSSENNEEKERTEEIELPTSELESKILNIEKIIAIENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYESM 112

[Close]

BLAST of Protein dpy-30-like vs. Planmine SMEST
Match: SMESG000066726.1 (SMESG000066726.1)

HSP 1 Score: 61.6178 bits (148), Expect = 1.866e-13
Identity = 25/58 (43.10%), Postives = 41/58 (70.69%), Query Frame = 1

Query:  193 KLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAY 366
            K K   +   +Q+L +R+YL++TV+P+++ G   L K+RP NPIE++A +LLK+K  Y
Sbjct:   14 KSKGSGSDANLQNLSARVYLDQTVVPVVLSGFKVLAKQRPNNPIEFLADYLLKHKDDY 71

[Close]

BLAST of Protein dpy-30-like vs. Planmine SMEST
Match: SMESG000075409.1 (SMESG000075409.1)

HSP 1 Score: 46.2098 bits (108), Expect = 1.947e-6
Identity = 21/51 (41.18%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  217 LEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEYMAAFLLKNKSAYE 369
            LE +S P R YL   V+P+L +G+   VK RP N I+++A +L +N   Y+
Sbjct:  663 LEEKSQPLRNYLMRHVMPVLTEGLIDCVKHRPDNAIDHLAEYLFRNNPQYD 713

The following BLAST results are available for this feature:

BLAST of Protein dpy-30-like vs. Ensembl Human
BLAST of Protein dpy-30-like vs. Ensembl Celegans
BLAST of Protein dpy-30-like vs. Ensembl Fly
BLAST of Protein dpy-30-like vs. Ensembl Zebrafish
BLAST of Protein dpy-30-like vs. Ensembl Xenopus
BLAST of Protein dpy-30-like vs. Ensembl Mouse
BLAST of Protein dpy-30-like vs. UniProt/SwissProt
BLAST of Protein dpy-30-like vs. TrEMBL
BLAST of Protein dpy-30-like vs. Ensembl Cavefish
BLAST of Protein dpy-30-like vs. Ensembl Sea Lamprey
BLAST of Protein dpy-30-like vs. Ensembl Yeast
BLAST of Protein dpy-30-like vs. Ensembl Nematostella
BLAST of Protein dpy-30-like vs. Ensembl Medaka
BLAST of Protein dpy-30-like vs. Planmine SMEST

BLAST of Protein dpy-30-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3


Match Name	E-value	Identity	Description
DPY30	2.068e-20	50.00	dpy-30 histone methyltransferase complex regulator...	[more]
DPY30	2.068e-20	50.00	dpy-30 histone methyltransferase complex regulator...	[more]
AK7	2.661e-7	47.83	adenylate kinase 7 [Source:HGNC Symbol;Acc:HGNC:20...	[more]

BLAST of Protein dpy-30-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
dpy-30	1.454e-13	52.08	Dosage compensation protein dpy-30 [Source:UniPro...	[more]
dpy-30	1.454e-13	52.08	Dosage compensation protein dpy-30 [Source:UniPro...	[more]

BLAST of Protein dpy-30-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Dpy-30L2	3.190e-12	40.30	gene:FBgn0035491 transcript:FBtr0073281	[more]
Dpy-30L2	3.190e-12	40.30	gene:FBgn0035491 transcript:FBtr0332981	[more]
Dpy-30L1	1.543e-11	40.00	gene:FBgn0032293 transcript:FBtr0080112	[more]
CG33060	7.590e-6	41.86	gene:FBgn0053060 transcript:FBtr0305307	[more]

BLAST of Protein dpy-30-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
dpy30	2.583e-20	53.42	dpy-30 histone methyltransferase complex regulator...	[more]
ak7b	2.232e-6	42.31	adenylate kinase 7b [Source:ZFIN;Acc:ZDB-GENE-0503...	[more]
dpy30	5.750e-6	42.59	dpy-30 histone methyltransferase complex regulator...	[more]

BLAST of Protein dpy-30-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gtf3c6	2.439e-21	52.11	general transcription factor IIIC subunit 6 [Sourc...	[more]
sesn1	2.272e-7	43.48	sestrin 1 [Source:Xenbase;Acc:XB-GENE-491636]	[more]
sesn1	2.316e-7	43.48	sestrin 1 [Source:Xenbase;Acc:XB-GENE-491636]	[more]
sesn1	2.339e-7	43.48	sestrin 1 [Source:Xenbase;Acc:XB-GENE-491636]	[more]
sesn1	2.644e-7	43.48	sestrin 1 [Source:Xenbase;Acc:XB-GENE-491636]	[more]

BLAST of Protein dpy-30-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Dpy30	7.138e-20	48.61	dpy-30, histone methyltransferase complex regulato...	[more]
Dpy30	7.138e-20	48.61	dpy-30, histone methyltransferase complex regulato...	[more]
Dpy30	7.138e-20	48.61	dpy-30, histone methyltransferase complex regulato...	[more]
Dpy30	7.138e-20	48.61	dpy-30, histone methyltransferase complex regulato...	[more]
Ak7	3.236e-8	47.83	adenylate kinase 7 [Source:MGI Symbol;Acc:MGI:1926...	[more]

BLAST of Protein dpy-30-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9C005\|DPY30_HUMAN	9.930e-20	50.00	Protein dpy-30 homolog OS=Homo sapiens OX=9606 GN=...	[more]
sp\|Q2NKU6\|DPY30_BOVIN	9.930e-20	50.00	Protein dpy-30 homolog OS=Bos taurus OX=9913 GN=DP...	[more]
sp\|Q99LT0\|DPY30_MOUSE	4.993e-19	48.61	Protein dpy-30 homolog OS=Mus musculus OX=10090 GN...	[more]
sp\|Q8K3E7\|DPY30_RAT	2.325e-18	47.22	Protein dpy-30 homolog OS=Rattus norvegicus OX=101...	[more]
sp\|Q10661\|DPY30_CAEEL	1.849e-12	52.08	Dosage compensation protein dpy-30 OS=Caenorhabdit...	[more]

BLAST of Protein dpy-30-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
L0H755	1.305e-48	98.81	Dpy30-1 (Fragment) OS=Schmidtea mediterranea OX=79...	[more]
L0H9N7	4.658e-36	94.29	Dpy30-1 (Fragment) OS=Schmidtea mediterranea OX=79...	[more]
C3XZ39	4.861e-21	57.75	Uncharacterized protein OS=Branchiostoma floridae ...	[more]
R7VAY8	1.618e-20	59.46	Uncharacterized protein OS=Capitella teleta OX=283...	[more]
A7RP67	4.700e-20	56.34	Predicted protein OS=Nematostella vectensis OX=453...	[more]

BLAST of Protein dpy-30-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
dpy30	3.622e-21	50.67	dpy-30 histone methyltransferase complex regulator...	[more]
ak7b	3.059e-6	43.48	adenylate kinase 7 [Source:NCBI gene;Acc:103041221...	[more]

BLAST of Protein dpy-30-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Protein dpy-30-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Protein dpy-30-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO46806	6.500e-24	56.34	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36546	3.298e-6	45.65	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein dpy-30-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
dpy30	8.589e-20	50.00	dpy-30 histone methyltransferase complex regulator...	[more]

BLAST of Protein dpy-30-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000008786.1	7.598e-62	99.11	SMESG000008786.1	[more]
SMESG000066726.1	1.866e-13	43.10	SMESG000066726.1	[more]
SMESG000075409.1	1.947e-6	41.18	SMESG000075409.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30006884 ID=SMED30006884|Name=Protein dpy-30-like|organism=Schmidtea mediterranea sexual|type=transcript|length=423bp
TTTAAATCTTAGTAACTAAGTAAAATAAATATGAAAAATATGAATGAATC
AAATAATATAGATGAATCCCATTTATTTTCATCAGAAAACAATGAAGAAA
AGGAACGGACTGAAGAAATTGAATTGCCAACTAGTGTGTTAGAATCTAAG
ATTTTAAACATAGAAAAAATAATTGCGATTGAAAATCAAAGAAAGCTAAA
ACCCAAACTTACAACATTAGAAATTCAATCTTTACCATCAAGATTATATT
TAGAAGAAACAGTTATACCAATTTTAATACAAGGAATGAATTATTTAGTT
AAAGAAAGACCGCCCAATCCAATTGAATATATGGCAGCTTTTCTCTTGAA
AAATAAATCTGCCTATGAATCTATGTGATGATTTTATGCTAAAATAATTA
ATGTTGTTCATTTTTAAAAAAAA

protein sequence of SMED30006884-orf-1

>SMED30006884-orf-1 ID=SMED30006884-orf-1|Name=SMED30006884-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=116bp
MKNMNESNNIDESHLFSSENNEEKERTEEIELPTSVLESKILNIEKIIAI
ENQRKLKPKLTTLEIQSLPSRLYLEETVIPILIQGMNYLVKERPPNPIEY
MAAFLLKNKSAYESM*

Aliases

The feature 'Protein dpy-30-like' has the following synonyms


Synonym
dpy30-1

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000020	protonephridia
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0000418	head
PLANA:0000429	neoblast
PLANA:0002032	epidermal cell
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR037856	Sdc1/DPY30
IPR007858	Dpy-30_motif

Vocabulary: **cellular component**
Term	Definition
GO:0000781	chromosome, telomeric region
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0035097	histone methyltransferase complex
GO:0044666	MLL3/4 complex
GO:0048188	Set1C/COMPASS complex

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0018024	histone-lysine N-methyltransferase activity
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity

Vocabulary: **biological process**
Term	Definition
GO:0006348	chromatin silencing at telomere
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0016197	endosomal transport
GO:0016569	covalent chromatin modification
GO:0051568	histone H3-K4 methylation

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	G3DSA:1.20.890.10		coord: 62..115 e-value: 2.9E-23 score: 83.3
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..32
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 16..32
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..15
IPR007858	Dpy-30 motif	PFAM	PF05186	Dpy-30	coord: 69..109 e-value: 2.6E-16 score: 59.0
IPR037856	Sdc1/DPY30	PANTHER	PTHR23356	DPY30-RELATED	coord: 31..111

Main menu

Protein dpy-30-like

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 15

Owlery

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