Peptidyl-prolyl cis-trans isomerase

Overview


Name	Peptidyl-prolyl cis-trans isomerase
Smed ID	SMED30006859
Length (bp)	666

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Peptidyl-prolyl cis-trans isomerase (SMED30006859) t-SNE clustered cells

Violin plots show distribution of expression levels for Peptidyl-prolyl cis-trans isomerase (SMED30006859) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Peptidyl-prolyl cis-trans isomerase (SMED30006859) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Peptidyl-prolyl cis-trans isomerase (SMED30006859) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30006859

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30006859	h1SMcG0013822	SmedASXL_008795	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
head region	SMED30006859	h1SMcG0013822	SmedASXL_008796	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30006859	h1SMcG0013822	dd_Smed_v4_10327_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30006859	h1SMcG0013822	dd_Smed_v4_10327_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30006859	h1SMcG0013822	dd_Smed_v4_10327_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30006859	h1SMcG0013822	dd_Smed_v4_10327_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30006859	h1SMcG0013822	dd_Smed_v6_13354_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30006859	h1SMcG0013822	dd_Smed_v6_10327_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
reproductive organ	SMED30006859	h1SMcG0013822	Contig39392	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30006859	h1SMcG0013822	Contig39392	newmark_ests	PMID:28434803 Rouhana et al., 2017
epidermis	SMED30006859	h1SMcG0013822	dd_Smed_v4_10327_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
epidermis	SMED30006859	h1SMcG0013822	dd_Smed_v4_13354_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Human
Match: PPIL6 (peptidylprolyl isomerase like 6 [Source:HGNC Symbol;Acc:HGNC:21557])

HSP 1 Score: 183.341 bits (464), Expect = 7.193e-57
Identity = 81/146 (55.48%), Postives = 112/146 (76.71%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            D+ PKTC+NF+ +CTG+ G S+        LHY+N+IF R+V NGW+QGGDI YG+G  GESIYGPTFEDE+F++ H++RG+L MAN+GRH+N SQF+ITL    ++D ++VAFG +IEG+E LK++E V T NERPI   +I ++
Sbjct:  133 DVCPKTCKNFQVLCTGKAGFSQRG----IRLHYKNSIFHRIVQNGWIQGGDIVYGKGDNGESIYGPTFEDENFSVPHNKRGVLGMANKGRHSNGSQFYITLQATPYLDRKFVAFGQLIEGTEVLKQLELVPTQNERPIHMCRITDS 274

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Human
Match: PPIL6 (peptidylprolyl isomerase like 6 [Source:HGNC Symbol;Acc:HGNC:21557])

HSP 1 Score: 182.956 bits (463), Expect = 2.256e-56
Identity = 81/146 (55.48%), Postives = 112/146 (76.71%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            D+ PKTC+NF+ +CTG+ G S+        LHY+N+IF R+V NGW+QGGDI YG+G  GESIYGPTFEDE+F++ H++RG+L MAN+GRH+N SQF+ITL    ++D ++VAFG +IEG+E LK++E V T NERPI   +I ++
Sbjct:  165 DVCPKTCKNFQVLCTGKAGFSQRG----IRLHYKNSIFHRIVQNGWIQGGDIVYGKGDNGESIYGPTFEDENFSVPHNKRGVLGMANKGRHSNGSQFYITLQATPYLDRKFVAFGQLIEGTEVLKQLELVPTQNERPIHMCRITDS 306

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Human
Match: PPIL6 (peptidylprolyl isomerase like 6 [Source:HGNC Symbol;Acc:HGNC:21557])

HSP 1 Score: 168.703 bits (426), Expect = 1.363e-50
Identity = 81/172 (47.09%), Postives = 112/172 (65.12%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFE--------------------------DESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            D+ PKTC+NF+ +CTG+ G S+        LHY+N+IF R+V NGW+QGGDI YG+G  GESIYGPTFE                          DE+F++ H++RG+L MAN+GRH+N SQF+ITL    ++D ++VAFG +IEG+E LK++E V T NERPI   +I ++
Sbjct:  165 DVCPKTCKNFQVLCTGKAGFSQRG----IRLHYKNSIFHRIVQNGWIQGGDIVYGKGDNGESIYGPTFEELYGSLKRSVKRQKESRGVGKIEKYRDENFSVPHNKRGVLGMANKGRHSNGSQFYITLQATPYLDRKFVAFGQLIEGTEVLKQLELVPTQNERPIHMCRITDS 332

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Human
Match: PPIG (peptidylprolyl isomerase G [Source:HGNC Symbol;Acc:HGNC:14650])

HSP 1 Score: 147.517 bits (371), Expect = 2.107e-43
Identity = 71/144 (49.31%), Postives = 97/144 (67.36%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKT-VNERPIKDIKI 429
            D+ PKTCENFR +CTGEKG  +  +     LHY++ +F R+V +  +QGGD   G G GGESIYG  FEDESFA+KH++  +LSMANRG+ TN SQFFIT  P   +D  +V FG +I G E ++++E  KT    +P  +++I
Sbjct:   31 DVCPKTCENFRCLCTGEKGTGKSTQKP---LHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRI 171

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Human
Match: PPIG (peptidylprolyl isomerase G [Source:HGNC Symbol;Acc:HGNC:14650])

HSP 1 Score: 147.132 bits (370), Expect = 5.228e-42
Identity = 71/144 (49.31%), Postives = 97/144 (67.36%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKT-VNERPIKDIKI 429
            D+ PKTCENFR +CTGEKG  +  +     LHY++ +F R+V +  +QGGD   G G GGESIYG  FEDESFA+KH++  +LSMANRG+ TN SQFFIT  P   +D  +V FG +I G E ++++E  KT    +P  +++I
Sbjct:   31 DVCPKTCENFRCLCTGEKGTGKSTQKP---LHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRI 171

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Celegans
Match: cyn-3 (Peptidyl-prolyl cis-trans isomerase 3 [Source:UniProtKB/Swiss-Prot;Acc:P52011])

HSP 1 Score: 136.732 bits (343), Expect = 1.779e-40
Identity = 65/145 (44.83%), Postives = 94/145 (64.83%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            D+VPKT  NFRA+CTGE G  +  +     LH++ + F R++PN  +QGGD   G G+GGESIYG  F DE+F  KH   G+LSMAN G +TN SQFF+      W+D ++V FG ++EG + +K +E+  + + +P+KD  I +
Sbjct:   27 DVVPKTAGNFRALCTGENGIGKSGK----PLHFKGSKFHRIIPNFMIQGGDFTRGNGTGGESIYGEKFPDENFKEKHTGPGVLSMANAGPNTNGSQFFLCTVKTEWLDGKHVVFGRVVEGLDVVKAVESNGSQSGKPVKDCMIAD 167

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Celegans
Match: cyn-7 (Peptidyl-prolyl cis-trans isomerase 7 [Source:UniProtKB/Swiss-Prot;Acc:P52015])

HSP 1 Score: 132.109 bits (331), Expect = 1.045e-38
Identity = 65/145 (44.83%), Postives = 92/145 (63.45%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            DIVPKT ENFRA+CTGEKG  +  +     LH++ + F R++P   +QGGD   G G+GGESIYG  F DE+F  KH   G+LSMAN G +TN SQFF+     +W+D ++V FG ++EG + + K+E   + +  P  +  I +
Sbjct:   27 DIVPKTAENFRALCTGEKGVGKSGK----PLHFKGSKFHRIIPEFMIQGGDFTRGNGTGGESIYGEKFPDENFKEKHTGPGVLSMANAGPNTNGSQFFLCTVKTAWLDGKHVVFGRVVEGLDIVSKVEGNGSSSGTPKSECLIAD 167

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Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            DIVPKT ENFRA+CTGEKG  +  +     LH++ + F R++P   +QGGD   G G+GGESIYG  F DE+F  KH   G+LSMAN G +TN SQFF+     +W+D ++V FG ++EG + + K+E   + +  P  +  I +
Sbjct:   27 DIVPKTAENFRALCTGEKGVGKSGK----PLHFKGSKFHRIIPEFMIQGGDFTRGNGTGGESIYGEKFPDENFKEKHTGPGVLSMANAGPNTNGSQFFLCTVKTAWLDGKHVVFGRVVEGLDIVSKVEGNGSSSGTPKSECLIAD 167

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Celegans
Match: cyn-1 (Peptidyl-prolyl cis-trans isomerase 1 [Source:UniProtKB/Swiss-Prot;Acc:P52009])

HSP 1 Score: 131.339 bits (329), Expect = 4.140e-38
Identity = 65/145 (44.83%), Postives = 89/145 (61.38%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            D+VPKT ENFRA+CTGEKG           LH++ + F R++P   +QGGD     G+GGESIYG  F+DE+F +KH   G LSMAN G +TN SQFFI      W+D  +V FG + +G   +KK+E + + +  P K + I +
Sbjct:   45 DVVPKTAENFRALCTGEKGVGEQGVA----LHFKGSKFHRIIPEFMIQGGDFTRHNGTGGESIYGNKFKDENFDLKHTGPGCLSMANAGPNTNGSQFFICTVDTPWLDGGHVVFGQVTDGMSVVKKIEKMGSRSGAPAKTVTIAD 185

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Celegans
Match: cyn-13 (Peptidyl-prolyl cis-trans isomerase [Source:UniProtKB/TrEMBL;Acc:D3NQB1])

HSP 1 Score: 130.954 bits (328), Expect = 1.421e-36
Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEP 453
            D+ PKT ENFR +CTGE+G             Y+ +IF R++P   LQGGD   G G+GG+SIYG  F+DE+F ++H   G +SMAN G +TN SQFFI      W+D ++V FG ++EG   ++++E   T + +P   +KI E+  +EP
Sbjct:  162 DVTPKTAENFRCLCTGERG-----------FGYEGSIFHRIIPKFMLQGGDFTKGDGTGGKSIYGTKFDDENFTLRHTMPGTVSMANCGANTNGSQFFICTEKTDWLDGKHVVFGHVVEGMNIVRQVEQQGTPSGKPQMVVKIVESGEIEP 301

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Fly
Match: Moca-cyp (gene:FBgn0039581 transcript:FBtr0085286)

HSP 1 Score: 144.05 bits (362), Expect = 3.014e-39
Identity = 73/144 (50.69%), Postives = 94/144 (65.28%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKT-VNERPIKDIKI 429
            D+ PKT ENFRA+CTGEKG      +    L Y+  IF R+V +  +Q GD   G G+GGESIYG TFEDESF  KHDR  +LSMANRG++TN SQFFIT  P   +D  +V FG +I G E ++++E +    N RP++D  I
Sbjct:   36 DVAPKTAENFRALCTGEKG---FGLITGKKLQYKGVIFHRVVKDFMVQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDNIHVVFGQVISGQELVRQLEGLPVDRNSRPLQDAAI 176

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Fly
Match: Cyp1 (gene:FBgn0004432 transcript:FBtr0074238)

HSP 1 Score: 134.806 bits (338), Expect = 4.866e-39
Identity = 66/146 (45.21%), Postives = 92/146 (63.01%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            D+VPKT ENFRA+CTGEKG             Y+ +IF R++PN   QGGD     G+GG+SIYG  F DE+F +KH   GILSMAN G +TN SQFFI     +W+D ++V FG ++EG + +KK+E+  + + +  K I +  +
Sbjct:   90 DVVPKTAENFRALCTGEKG-----------FGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEVVEGLDVVKKIESYGSQSGKTSKKIIVANS 224

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Fly
Match: CG7768 (gene:FBgn0036415 transcript:FBtr0075736)

HSP 1 Score: 129.028 bits (323), Expect = 1.981e-37
Identity = 63/145 (43.45%), Postives = 91/145 (62.76%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            D+VPKT ENFRA+CTGEKG             Y+ + F R++PN   QGGD     G+GG SIYG  F DE+F +KH   G+LSMAN G +TN SQFFI     +W+D ++V FG ++EG + ++K+E+  + + +  K + I++
Sbjct:   27 DVVPKTAENFRALCTGEKGYG-----------YKGSPFHRVIPNFMCQGGDFTNQNGTGGRSIYGNKFPDENFELKHTGAGVLSMANAGANTNGSQFFICTGKTTWLDNKHVVFGKVVEGMDIVQKVESYGSQDGKTSKKVIIED 160

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Fly
Match: CG7768 (gene:FBgn0036415 transcript:FBtr0075737)

HSP 1 Score: 129.028 bits (323), Expect = 1.981e-37
Identity = 63/145 (43.45%), Postives = 91/145 (62.76%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            D+VPKT ENFRA+CTGEKG             Y+ + F R++PN   QGGD     G+GG SIYG  F DE+F +KH   G+LSMAN G +TN SQFFI     +W+D ++V FG ++EG + ++K+E+  + + +  K + I++
Sbjct:   27 DVVPKTAENFRALCTGEKGYG-----------YKGSPFHRVIPNFMCQGGDFTNQNGTGGRSIYGNKFPDENFELKHTGAGVLSMANAGANTNGSQFFICTGKTTWLDNKHVVFGKVVEGMDIVQKVESYGSQDGKTSKKVIIED 160

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Fly
Match: cyp33 (gene:FBgn0028382 transcript:FBtr0086945)

HSP 1 Score: 122.479 bits (306), Expect = 2.006e-33
Identity = 62/143 (43.36%), Postives = 84/143 (58.74%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKI 429
            D+VPKT ENFR +CT E+G             Y+   F R++P    QGGD     G+GG+SIYG  F DE+F +KH+  G LSMAN G +TN SQFFI      W+D ++V FG +I G+E ++KME   + +  P + I I
Sbjct:  162 DVVPKTAENFRQLCTHEQG-----------YGYKGCSFHRVIPEFMCQGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTLSMANSGANTNGSQFFICTTKTDWLDNKHVVFGHVISGAEVVRKMERCGSKSGTPSQKIVI 293

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Zebrafish
Match: ppil6 (peptidylprolyl isomerase (cyclophilin)-like 6 [Source:ZFIN;Acc:ZDB-GENE-050522-70])

HSP 1 Score: 190.66 bits (483), Expect = 1.200e-59
Identity = 88/144 (61.11%), Postives = 112/144 (77.78%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIW-YGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKI 429
            D+ PKTC NF+A+CTGE G S+ N      L Y+ +IF R+VPNGW+QGGDI    +G+GGESIYGPTFEDE+F I H++RGIL MAN+G H+N SQF+ITL P +WMD +YVAFG ++EG+E LK++EAV T NERP +D KI
Sbjct:  161 DVCPKTCRNFKALCTGEAGLSKSN----LELSYKGSIFHRVVPNGWIQGGDISPEKKGTGGESIYGPTFEDENFVISHNKRGILGMANQGAHSNGSQFYITLQPATWMDHKYVAFGQLVEGTEVLKRLEAVPTYNERPKQDCKI 300

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Zebrafish
Match: ppid (peptidylprolyl isomerase D [Source:ZFIN;Acc:ZDB-GENE-040625-34])

HSP 1 Score: 141.739 bits (356), Expect = 4.546e-40
Identity = 70/146 (47.95%), Postives = 95/146 (65.07%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            D+VPKT ENFRA+CTGEKG  +        LH++   F R++ +  +QGGD     G+GGESIYG  FEDE+F  KHDR G+LSMAN G +TN SQFFIT  P   +D ++V FG +++G   +K +EA++T  + P+K   I E 
Sbjct:   39 DVVPKTAENFRALCTGEKGVGKSTGKP---LHFKGCPFHRIIKSFMIQGGDFSNQNGTGGESIYGDKFEDENFHYKHDREGLLSMANAGPNTNGSQFFITTVPTPHLDGKHVVFGQVLKGMGVVKMLEAMETKEDNPVKPCVIAEC 181

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Zebrafish
Match: ppifb (peptidylprolyl isomerase Fb [Source:ZFIN;Acc:ZDB-GENE-051030-126])

HSP 1 Score: 135.961 bits (341), Expect = 8.816e-40
Identity = 69/145 (47.59%), Postives = 92/145 (63.45%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            D+VPKT ENFRA+CTGE G             Y+ +IF R++P    QGGD     G+GG+SIYGP F DE+F +KH   GILSMAN G +TN SQFFI  A   W+D R+V FGS+ EG + ++K+EA+ + + R  + I I +
Sbjct:   54 DVVPKTAENFRALCTGEHG-----------FGYKGSIFHRVIPQFMCQGGDFTNHNGTGGKSIYGPRFPDENFKLKHTGPGILSMANAGVNTNGSQFFICTAKTEWLDGRHVVFGSVKEGMDVVRKVEALGSRSGRTAQRISITD 187

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Zebrafish
Match: ppig (peptidylprolyl isomerase G (cyclophilin G) [Source:ZFIN;Acc:ZDB-GENE-040426-2822])

HSP 1 Score: 143.665 bits (361), Expect = 3.448e-39
Identity = 72/144 (50.00%), Postives = 96/144 (66.67%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKT-VNERPIKDIKI 429
            D+ PKTCENFR +CTGEKG  +  +     LHY+ T F R+V +  +QGGD   G G GGESIYG  FEDESF++KH +  +LSMANRG+ TN SQFFIT  P   +D  +V FG +I G + ++ +E+ KT  N RP  ++K+
Sbjct:   31 DVCPKTCENFRCLCTGEKGVGKTTQKP---LHYKGTPFHRIVKDFMIQGGDFSEGNGRGGESIYGGFFEDESFSMKHTKEFLLSMANRGKDTNGSQFFITTKPTPHLDGIHVVFGQVITGQDVIRMIESQKTDTNSRPYAEVKV 171

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Zebrafish
Match: RANBP2 (si:ch1073-55a19.2 [Source:ZFIN;Acc:ZDB-GENE-081104-93])

HSP 1 Score: 138.658 bits (348), Expect = 3.622e-37
Identity = 67/142 (47.18%), Postives = 90/142 (63.38%), Query Frame = 1

Query:    4 IVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKI 429
            IVPKT ENFRA+CTGEKG             Y  +IF R++P+   QGGDI +  G+GG SIYG  FEDESF ++H   G+LSMANRGR +N SQFF+TL     +D ++VAFG + +G + L+++  + T   +P   I I
Sbjct: 2800 IVPKTAENFRALCTGEKG-----------FGYSGSIFHRIIPDFMCQGGDITHQDGTGGRSIYGHAFEDESFEVRHTGPGLLSMANRGRDSNSSQFFLTLRKAEHLDYKHVAFGFVTDGMQVLRRLAEMGTKEGKPTHTITI 2930

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Xenopus
Match: PPIL6 (peptidylprolyl isomerase like 6 [Source:NCBI gene;Acc:100496026])

HSP 1 Score: 183.341 bits (464), Expect = 1.095e-56
Identity = 84/151 (55.63%), Postives = 110/151 (72.85%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEP 453
            D+ PKTCENF+++CTG  G S    +    LHY+++IF R+V NGW+QGGDI  G+GSGGESI+G TFEDE+FA+ H +RGIL MAN+GRH+N SQF+ITL P S++D R VAFG ++EG   LK++E + T NERP  D KI +     P
Sbjct:  158 DLCPKTCENFQSLCTGAAGVS----LSGLKLHYKDSIFHRIVKNGWIQGGDIESGKGSGGESIFGETFEDENFAVPHSKRGILGMANKGRHSNGSQFYITLQPTSYLDRRCVAFGQLVEGCGVLKEIEDIPTYNERPTTDCKITDCGIFTP 304

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Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEP 453
            D+ PKTCENF+++CTG  G S    +    LHY+++IF R+V NGW+QGGDI  G+GSGGESI+G TFEDE+FA+ H +RGIL MAN+GRH+N SQF+ITL P S++D R VAFG ++EG   LK++E + T NERP  D KI +     P
Sbjct:  158 DLCPKTCENFQSLCTGAAGVS----LSGLKLHYKDSIFHRIVKNGWIQGGDIESGKGSGGESIFGETFEDENFAVPHSKRGILGMANKGRHSNGSQFYITLQPTSYLDRRCVAFGQLVEGCGVLKEIEDIPTYNERPTTDCKITDCGIFTP 304

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Xenopus
Match: ppia (peptidylprolyl isomerase A (cyclophilin A) [Source:NCBI gene;Acc:394470])

HSP 1 Score: 132.88 bits (333), Expect = 1.166e-38
Identity = 66/143 (46.15%), Postives = 91/143 (63.64%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKI 429
            D+VPKT ENFRA+CT EKG             Y+N+ F R++P    QGGD     G+GG+SIYG  F DE+F ++H   GILSMAN G +TN SQFFI  A  SW+D ++V FG++I+G + ++ ME + + + +P K I I
Sbjct:   27 DVVPKTAENFRALCTNEKG-----------FGYKNSGFHRIIPEFMCQGGDFTNHNGTGGKSIYGNKFADENFQLRHTGPGILSMANAGANTNGSQFFICTAKTSWLDGKHVVFGTVIDGMDVVRNMEKLGSQSGKPAKKIVI 158

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Xenopus
Match: ppig (peptidylprolyl isomerase G (cyclophilin G) [Source:NCBI gene;Acc:407915])

HSP 1 Score: 140.969 bits (354), Expect = 6.130e-38
Identity = 69/145 (47.59%), Postives = 99/145 (68.28%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKT-VNERPIKDIKIK 432
            D+ PKTCENFR++CTGE+G  +  +     LHY+N +F R+V +  +QGGD   G G GGESIYG  FEDE+F+I+H++  +LSMANRG+ TN SQFFIT  P   +D  +V FG +I G + ++++E  KT  + +P  D+ I+
Sbjct:   31 DVCPKTCENFRSLCTGERGIGKSTQKP---LHYKNCMFHRVVKDFMIQGGDFSEGNGRGGESIYGGFFEDENFSIQHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGLHVVFGQVISGQDLVREIENQKTDASSKPSVDVSIQ 172

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Xenopus
Match: neurl4 (neuralized E3 ubiquitin protein ligase 4 [Source:Xenbase;Acc:XB-GENE-5825550])

HSP 1 Score: 130.954 bits (328), Expect = 1.592e-37
Identity = 65/146 (44.52%), Postives = 89/146 (60.96%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            D+VPKT ENFRA+CTGEKG             Y+ + F R++PN   QGGD     G+GG+SIYG  F DE+F +KH   G++SMAN G +TN SQFFI      W+D ++V FG I +G + +KK+E+  +   RP K + + E 
Sbjct:   62 DVVPKTAENFRALCTGEKG-----------FGYKGSTFHRIIPNFMCQGGDFTNHNGTGGKSIYGSRFPDENFFLKHTGPGVVSMANAGPNTNGSQFFICTVETEWLDNKHVVFGCIKDGYDIMKKIESFGSKTGRPSKKVVVAEC 196

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Mouse
Match: Ppil6 (peptidylprolyl isomerase (cyclophilin)-like 6 [Source:MGI Symbol;Acc:MGI:1920325])

HSP 1 Score: 171.014 bits (432), Expect = 6.852e-52
Identity = 78/146 (53.42%), Postives = 103/146 (70.55%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            D  P+TC NF+ +CTG  G S         LHY+++IF R+V NGW+QGGDI  GRG  GESIYGPTFEDE+F+I H++RG+L M N+G HTN SQF+ITL    ++D +YVAFG +IEG+  LK++E V T NERP+    I ++
Sbjct:  167 DACPRTCTNFQVLCTGTSGFSERGT----KLHYKDSIFHRVVQNGWIQGGDIVQGRGDDGESIYGPTFEDENFSIPHNKRGVLGMVNKGHHTNGSQFYITLQAAPYLDKKYVAFGQLIEGTHVLKQLELVPTENERPLLLCSIADS 308

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Mouse
Match: Ppig (peptidyl-prolyl isomerase G (cyclophilin G) [Source:MGI Symbol;Acc:MGI:2445173])

HSP 1 Score: 146.362 bits (368), Expect = 4.951e-40
Identity = 71/144 (49.31%), Postives = 97/144 (67.36%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKT-VNERPIKDIKI 429
            D+ PKTCENFR +CTGEKG  +  +     LHY++ +F R+V +  +QGGD   G G GGESIYG  FEDESFA+KH++  +LSMANRG+ TN SQFFIT  P   +D  +V FG +I G E ++++E  KT    +P  +++I
Sbjct:   31 DVCPKTCENFRCLCTGEKGTGKSTQKP---LHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRI 171

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Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKT-VNERPIKDIKI 429
            D+ PKTCENFR +CTGEKG  +  +     LHY++ +F R+V +  +QGGD   G G GGESIYG  FEDESFA+KH++  +LSMANRG+ TN SQFFIT  P   +D  +V FG +I G E ++++E  KT    +P  +++I
Sbjct:   31 DVCPKTCENFRCLCTGEKGTGKSTQKP---LHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRI 171

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Mouse
Match: Ppil6 (peptidylprolyl isomerase (cyclophilin)-like 6 [Source:MGI Symbol;Acc:MGI:1920325])

HSP 1 Score: 130.568 bits (327), Expect = 3.146e-38
Identity = 63/146 (43.15%), Postives = 88/146 (60.27%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            D  P+TC NF+ +CTG  G S         LHY+++IF R+V NGW+QGGD                   E+F+I H++RG+L M N+G HTN SQF+ITL    ++D +YVAFG +IEG+  LK++E V T NERP+    I ++
Sbjct:   17 DACPRTCTNFQVLCTGTSGFSERGT----KLHYKDSIFHRVVQNGWIQGGD-------------------ENFSIPHNKRGVLGMVNKGHHTNGSQFYITLQAAPYLDKKYVAFGQLIEGTHVLKQLELVPTENERPLLLCSIADS 139

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Mouse
Match: Ppid (peptidylprolyl isomerase D (cyclophilin D) [Source:MGI Symbol;Acc:MGI:1914988])

HSP 1 Score: 136.346 bits (342), Expect = 5.374e-38
Identity = 71/145 (48.97%), Postives = 90/145 (62.07%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            DIVPKT ENFRA+CTGEKG           LH++   F R++    +QGGD     G+GGESIYG  FEDE+F  KHDR G+LSMAN G +TN SQFFIT  P   +D ++V FG +I+G    + +E V+   E+P K   I E
Sbjct:   39 DIVPKTAENFRALCTGEKGTG---STTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQFFITTVPTPHLDGKHVVFGQVIKGLGVARTLENVEVNGEKPAKLCVIAE 180

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. UniProt/SwissProt
Match: sp|Q8IXY8|PPIL6_HUMAN (Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 OS=Homo sapiens OX=9606 GN=PPIL6 PE=1 SV=1)

HSP 1 Score: 182.956 bits (463), Expect = 1.083e-55
Identity = 81/146 (55.48%), Postives = 112/146 (76.71%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            D+ PKTC+NF+ +CTG+ G S+        LHY+N+IF R+V NGW+QGGDI YG+G  GESIYGPTFEDE+F++ H++RG+L MAN+GRH+N SQF+ITL    ++D ++VAFG +IEG+E LK++E V T NERPI   +I ++
Sbjct:  165 DVCPKTCKNFQVLCTGKAGFSQRG----IRLHYKNSIFHRIVQNGWIQGGDIVYGKGDNGESIYGPTFEDENFSVPHNKRGVLGMANKGRHSNGSQFYITLQATPYLDRKFVAFGQLIEGTEVLKQLELVPTQNERPIHMCRITDS 306

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. UniProt/SwissProt
Match: sp|Q1RMP7|PPIL6_BOVIN (Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 OS=Bos taurus OX=9913 GN=PPIL6 PE=2 SV=1)

HSP 1 Score: 171.4 bits (433), Expect = 2.493e-51
Identity = 77/143 (53.85%), Postives = 105/143 (73.43%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKI 429
            D  PKTC+NF+ +CTG+ G S+        LHY  +IF R+V NGW+QGGDI  G+G  GESIYGPTFEDE+F++ H++RG+L M N+GRH+N SQF+ITL    ++D +YVAFG +IEG++ L  +E+V T NERPI++  I
Sbjct:  161 DTCPKTCKNFQILCTGKAGFSQSG----IKLHYTGSIFHRVVRNGWVQGGDIVAGKGDNGESIYGPTFEDENFSVPHNKRGVLGMVNKGRHSNGSQFYITLQAAPYLDKKYVAFGQLIEGTDVLHHLESVPTENERPIQNCVI 299

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. UniProt/SwissProt
Match: sp|P0C1I1|PPID_RHIO9 (Peptidyl-prolyl cis-trans isomerase D OS=Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) OX=246409 GN=cyp12 PE=3 SV=1)

HSP 1 Score: 151.369 bits (381), Expect = 6.369e-43
Identity = 71/143 (49.65%), Postives = 100/143 (69.93%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKI 429
            DIVPKT ENFRA+CTGEKGE +  +     L YQ ++F R++ N  +QGGD   G G+GGESIYG  FEDE+F +KH++  +LSMAN G  TN SQFFIT  P   +D ++V FG +++G   ++ +E ++TV++RP++D  I
Sbjct:   27 DIVPKTAENFRALCTGEKGEGKSGKP----LSYQGSLFHRIIKNFMIQGGDFTAGNGTGGESIYGEKFEDENFVLKHEKPFLLSMANAGPGTNGSQFFITTVPTPHLDGKHVVFGKVLKGKAVVRALENLETVSDRPVEDAVI 165

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. UniProt/SwissProt
Match: sp|Q9TW32|PPIB_DICDI (Peptidyl-prolyl cis-trans isomerase B OS=Dictyostelium discoideum OX=44689 GN=cypB PE=1 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 1.485e-42
Identity = 72/144 (50.00%), Postives = 96/144 (66.67%), Query Frame = 1

Query:    7 VPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            VPKT ENFRA+CTGEKG     +     LHY+++ F R++PN  +QGGD   G G+GGESIYG  F DE+F IKH + G+LSMAN G +TN SQFFIT    SW+D R+  FG +IEG + +K +E++ + +  P K  KI  +
Sbjct:   55 VPKTVENFRALCTGEKGLGTSGK----PLHYKDSKFHRIIPNFMIQGGDFTRGDGTGGESIYGKKFNDENFKIKHSKPGLLSMANAGPNTNGSQFFITTVVTSWLDGRHTVFGEVIEGMDIVKLLESIGSQSGTPSKIAKISNS 194

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. UniProt/SwissProt
Match: sp|Q9SKQ0|CP19B_ARATH (Peptidyl-prolyl cis-trans isomerase CYP19-2 OS=Arabidopsis thaliana OX=3702 GN=CYP19-2 PE=2 SV=1)

HSP 1 Score: 141.739 bits (356), Expect = 2.525e-41
Identity = 69/145 (47.59%), Postives = 93/145 (64.14%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            D  PKT ENFRA+CTGEKG  R  +     LH++ + F R++PN   QGGD   G G+GGESIYG  FEDE+F  KH   GILSMAN G +TN SQFFI      W+D ++V FG ++EG + +K +E + + + +P K + I +
Sbjct:   28 DKTPKTAENFRALCTGEKGVGRSGK----PLHFKGSSFHRVIPNFMCQGGDFTKGNGTGGESIYGAKFEDENFERKHTGPGILSMANAGANTNGSQFFICTVKTDWLDGKHVVFGQVVEGLDVVKAIEKIGSSSGKPTKPVVIAD 168

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. TrEMBL
Match: A0A5J4NBN4 (Peptidyl-prolyl cis-trans isomerase OS=Paragonimus westermani OX=34504 GN=DEA37_0002963 PE=3 SV=1)

HSP 1 Score: 234.187 bits (596), Expect = 5.185e-74
Identity = 107/152 (70.39%), Postives = 127/152 (83.55%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEPR 456
            D++PKTCENFRA+CTGEK E R NEVE++N+HY+ T+FFRLV NGW+QGGD+ Y RG+ G SIYG TFEDE+FAIKHDRRGILSMAN GRHTN SQFFITLAP  WMD  YVAFG ++EGS TL KME V T NERPIK+I+I + + V+P+
Sbjct:  103 DVLPKTCENFRALCTGEKKEIRKNEVESYNMHYKGTLFFRLVKNGWIQGGDVMYNRGNDGCSIYGRTFEDENFAIKHDRRGILSMANAGRHTNGSQFFITLAPTPWMDNVYVAFGRLVEGSMTLDKMEEVPTENERPIKEIRISDVRIVDPK 254

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. TrEMBL
Match: A0A4E0R9D1 (Peptidyl-prolyl cis-trans isomerase OS=Fasciola hepatica OX=6192 GN=D915_006284 PE=4 SV=1)

HSP 1 Score: 231.491 bits (589), Expect = 2.379e-72
Identity = 106/156 (67.95%), Postives = 126/156 (80.77%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEPRLAET 468
            D++PKTCENFRA+CTGEKG+   N VE++ +HY+NT+FFR V NGW+QGGD+ Y RG+ G SIYG TFEDE+FAIKHDRRGI+SMAN GRHTN SQFFITLAP  WMD  YVAFG ++EGSETL+KME V TVNERP+KD+ I E   + P   ET
Sbjct:  145 DLLPKTCENFRALCTGEKGKVPKNSVESYTMHYKNTLFFRCVKNGWIQGGDVLYNRGNDGCSIYGRTFEDENFAIKHDRRGIVSMANAGRHTNGSQFFITLAPTPWMDNLYVAFGRVVEGSETLEKMENVPTVNERPMKDVCIAEINVMNPLRLET 300

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. TrEMBL
Match: A0A504Y8P7 (Peptidyl-prolyl cis-trans isomerase OS=Fasciola gigantica OX=46835 GN=FGIG_03426 PE=4 SV=1)

HSP 1 Score: 231.491 bits (589), Expect = 2.458e-72
Identity = 106/156 (67.95%), Postives = 126/156 (80.77%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEPRLAET 468
            D++PKTCENFRA+CTGEKG+   N VE++ +HY+NT+FFR V NGW+QGGD+ Y RG+ G SIYG TFEDE+FAIKHDRRGI+SMAN GRHTN SQFFITLAP  WMD  YVAFG ++EGSETL+KME V TVNERP+KD+ I E   + P   ET
Sbjct:  145 DLLPKTCENFRALCTGEKGKVPKNSVESYTMHYKNTLFFRCVKNGWIQGGDVLYNRGNDGCSIYGRTFEDENFAIKHDRRGIVSMANAGRHTNGSQFFITLAPTPWMDNLYVAFGRVVEGSETLEKMENVPTVNERPMKDVCIAEINVMNPLRLET 300

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. TrEMBL
Match: A0A419PPI0 (Peptidyl-prolyl cis-trans isomerase OS=Clonorchis sinensis OX=79923 GN=PPIL6 PE=3 SV=1)

HSP 1 Score: 224.557 bits (571), Expect = 7.035e-70
Identity = 105/152 (69.08%), Postives = 122/152 (80.26%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEPR 456
            DI+PKTCENFRA+CTGEKG    NEVE++ +HY+ T+FFRLV NGW+QGGD+ + RG+ G SIYG TFEDE+FAIKHDRRGILSMAN GRHTN SQFFITLAP  WMD  YVAFG +IEGS TL  ME V T NERP KDI I E + ++P+
Sbjct:  123 DILPKTCENFRALCTGEKGLVPKNEVESYKMHYKGTLFFRLVRNGWIQGGDVLHSRGNDGCSIYGRTFEDENFAIKHDRRGILSMANAGRHTNDSQFFITLAPTPWMDNLYVAFGRVIEGSLTLDLMEEVPTQNERPTKDICISEIQIMDPK 274

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. TrEMBL
Match: A0A4S2LKQ6 (Peptidyl-prolyl cis-trans isomerase OS=Opisthorchis felineus OX=147828 GN=CRM22_006511 PE=3 SV=1)

HSP 1 Score: 224.942 bits (572), Expect = 9.077e-70
Identity = 104/152 (68.42%), Postives = 122/152 (80.26%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEPR 456
            DI+PKTCENFRA+CTGE G    NEVE++ +HY+ T+FFRLV NGW+QGGD+ + RG+ G SIYG TFEDE+FAIKHDRRGILSMAN GRHTN SQFFITLAP  WMD  YVAFG +IEGS TL  ME V T NERP+KDI I E + ++P+
Sbjct:  142 DILPKTCENFRALCTGENGLVPKNEVESYKMHYKGTLFFRLVKNGWIQGGDVLHSRGNDGCSIYGRTFEDENFAIKHDRRGILSMANAGRHTNDSQFFITLAPTPWMDNLYVAFGRVIEGSLTLDLMEEVPTQNERPMKDICISEIQIMDPK 293

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Cavefish
Match: ppil6 (peptidylprolyl isomerase like 6 [Source:NCBI gene;Acc:103033169])

HSP 1 Score: 186.037 bits (471), Expect = 3.732e-58
Identity = 86/152 (56.58%), Postives = 112/152 (73.68%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIW-YGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEP 453
            D+ PKTC+NF+A+CTGE G S++       L Y+N++F R+VPNGWLQGGDI   G+G+GGESIYG TF DE FA+ H++RGIL MAN+G H+N SQF+ITL P  WMDT YVAFG ++EG++ L+K+E V T NERP +D +I       P
Sbjct:  146 DLCPKTCKNFKALCTGEAGMSQNQ----LMLSYKNSLFHRVVPNGWLQGGDITPAGKGNGGESIYGATFGDEGFAVSHNKRGILGMANQGPHSNGSQFYITLQPALWMDTNYVAFGQVVEGTDVLRKLEEVPTYNERPKQDCRIVACGLFNP 293

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Cavefish
Match: ENSAMXT00000043946.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001973.1:152187:156122:-1 gene:ENSAMXG00000041718.1 transcript:ENSAMXT00000043946.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 135.576 bits (340), Expect = 3.975e-40
Identity = 67/142 (47.18%), Postives = 93/142 (65.49%), Query Frame = 1

Query:    4 IVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKI 429
            IVPKT ENFR +CTGEKG             Y+N++F R++P+   QGGDI    G+GG+S+YG  FEDE+F ++H   G+LSMANRGR TN SQFFITL     +D ++VAFG +  G + +K+M  + + + +P K IK+
Sbjct:   13 IVPKTAENFRLLCTGEKG-----------FGYRNSVFHRIIPDFMCQGGDITNQDGTGGKSVYGGKFEDENFDVRHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVAFGFVRNGMDVVKQMGEMGSKSGKPSKTIKV 143

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Cavefish
Match: ENSAMXT00000049365.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001973.1:152187:155501:-1 gene:ENSAMXG00000041718.1 transcript:ENSAMXT00000049365.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 135.576 bits (340), Expect = 5.710e-40
Identity = 67/142 (47.18%), Postives = 93/142 (65.49%), Query Frame = 1

Query:    4 IVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKI 429
            IVPKT ENFR +CTGEKG             Y+N++F R++P+   QGGDI    G+GG+S+YG  FEDE+F ++H   G+LSMANRGR TN SQFFITL     +D ++VAFG +  G + +K+M  + + + +P K IK+
Sbjct:   27 IVPKTAENFRLLCTGEKG-----------FGYRNSVFHRIIPDFMCQGGDITNQDGTGGKSVYGGKFEDENFDVRHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVAFGFVRNGMDVVKQMGEMGSKSGKPSKTIKV 157

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Cavefish
Match: ENSAMXT00000033420.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001973.1:152187:154187:-1 gene:ENSAMXG00000041718.1 transcript:ENSAMXT00000033420.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 135.191 bits (339), Expect = 7.698e-40
Identity = 67/142 (47.18%), Postives = 93/142 (65.49%), Query Frame = 1

Query:    4 IVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKI 429
            IVPKT ENFR +CTGEKG             Y+N++F R++P+   QGGDI    G+GG+S+YG  FEDE+F ++H   G+LSMANRGR TN SQFFITL     +D ++VAFG +  G + +K+M  + + + +P K IK+
Sbjct:   32 IVPKTAENFRLLCTGEKG-----------FGYRNSVFHRIIPDFMCQGGDITNQDGTGGKSVYGGKFEDENFDVRHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVAFGFVRNGMDVVKQMGEMGSKSGKPSKTIKV 162

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Cavefish
Match: ENSAMXT00000048079.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001973.1:152187:155587:-1 gene:ENSAMXG00000041718.1 transcript:ENSAMXT00000048079.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 135.191 bits (339), Expect = 8.738e-40
Identity = 67/142 (47.18%), Postives = 93/142 (65.49%), Query Frame = 1

Query:    4 IVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKI 429
            IVPKT ENFR +CTGEKG             Y+N++F R++P+   QGGDI    G+GG+S+YG  FEDE+F ++H   G+LSMANRGR TN SQFFITL     +D ++VAFG +  G + +K+M  + + + +P K IK+
Sbjct:   33 IVPKTAENFRLLCTGEKG-----------FGYRNSVFHRIIPDFMCQGGDITNQDGTGGKSVYGGKFEDENFDVRHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVAFGFVRNGMDVVKQMGEMGSKSGKPSKTIKV 163

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010135.1 (pep scaffold:Pmarinus_7.0:GL476417:32947:40880:1 gene:ENSPMAG00000009125.1 transcript:ENSPMAT00000010135.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 138.272 bits (347), Expect = 1.033e-41
Identity = 67/145 (46.21%), Postives = 93/145 (64.14%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            D+VPKT ENFRA+CTGEKG             Y+ + F R++P+   QGGD   G G+GG+SIYG  FEDE+F +KH+  GILSMAN G +TN SQFFI  A  +W+D ++V FG +I G + +KK+E+    + +  K I + +
Sbjct:   27 DVVPKTAENFRALCTGEKG-----------FGYKGSTFHRVIPDFMCQGGDFTKGNGTGGKSIYGNKFEDENFTLKHEGPGILSMANAGPNTNGSQFFICTAKTAWLDNKHVVFGKVISGLDVIKKVESYGAASGKTSKKIVVAD 160

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Sea Lamprey
Match: ppig (peptidylprolyl isomerase G (cyclophilin G) [Source:ZFIN;Acc:ZDB-GENE-040426-2822])

HSP 1 Score: 144.821 bits (364), Expect = 2.416e-40
Identity = 72/144 (50.00%), Postives = 96/144 (66.67%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKT-VNERPIKDIKI 429
            D+ PKTCENFR +CTGE+G  +   +    LH+++T F R+V N  +QGGD   G G GGESIYG  FEDE+F +KHD+  +LSMANRG+ TN SQFFIT  P   +D  +V FG ++ G + LK++E  KT  N  P  DI++
Sbjct:   30 DVCPKTCENFRCLCTGERGIGK---ITRKPLHFRSTSFHRIVKNFMVQGGDFSEGNGRGGESIYGGFFEDENFQLKHDQEFLLSMANRGKDTNGSQFFITTKPAPHLDGEHVVFGRVLSGQDLLKEIENQKTDANSLPYADIRV 170

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Sea Lamprey
Match: ppifb (peptidylprolyl isomerase Fb [Source:ZFIN;Acc:ZDB-GENE-051030-126])

HSP 1 Score: 128.642 bits (322), Expect = 7.703e-38
Identity = 64/130 (49.23%), Postives = 83/130 (63.85%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAV 390
            D+VPKT ENFRA+CTGE G             Y+ +IF R++PN   QGGD     G+GG SIYG TF DE+F +KH   GILSMAN G++TN SQFFI     +W+D ++V FG +  G + +KKME +
Sbjct:   37 DVVPKTAENFRALCTGEHG-----------FGYKGSIFHRIIPNFMCQGGDFTRNNGTGGVSIYGTTFRDENFILKHTGPGILSMANAGKNTNGSQFFICTELTNWLDGKHVVFGHVTSGMDIVKKMEKL 155

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004654.1 (pep scaffold:Pmarinus_7.0:GL489343:42315:43690:-1 gene:ENSPMAG00000004243.1 transcript:ENSPMAT00000004654.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 123.635 bits (309), Expect = 2.192e-35
Identity = 64/146 (43.84%), Postives = 87/146 (59.59%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            ++VP+T ENFRA+CT E G             Y+N+   R++P    QGGD     G+GG SIY   FEDESF I H R GILSMAN GR+TN SQFFITL   S +D ++VAFG++  G   ++ ME + + +    K I + ++
Sbjct:   79 NVVPRTAENFRALCTHEHG-----------FGYRNSTIHRVIPGFMCQGGDFTNHNGTGGRSIYEKPFEDESFKILHSRAGILSMANSGRNTNTSQFFITLRATSHLDHKHVAFGAVRSGMSIVRAMEELGSQSGNTTKKIVVTDS 213

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004873.1 (pep scaffold:Pmarinus_7.0:GL486356:449:3367:-1 gene:ENSPMAG00000004429.1 transcript:ENSPMAT00000004873.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.842 bits (268), Expect = 2.193e-30
Identity = 56/100 (56.00%), Postives = 67/100 (67.00%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCT-GEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFI 297
            D+ PKTCENFR +CT GE+G  +        LHY+ T F R+V    +QGGD   G G GGESIYG  F DESFA+KHD   +LSMANRG+ TN SQFF+
Sbjct:   30 DVCPKTCENFRCLCTAGERGVGKTTLKP---LHYKGTPFHRIVKEFMIQGGDFSEGNGKGGESIYGGFFNDESFAVKHDEDFLLSMANRGKDTNGSQFFM 126

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Yeast
Match: CPR1 (Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A; N-terminally propionylated in vivo; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002562])

HSP 1 Score: 136.346 bits (342), Expect = 2.773e-41
Identity = 66/130 (50.77%), Postives = 87/130 (66.92%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAV 390
            DIVPKT ENFRA+CTGEKG             Y  + F R++P+  LQGGD   G G+GG+SIYG  F DE+F   HDR G+LSMAN G +TN SQFFIT  P  W+D ++V FG +++G + +KK+E++
Sbjct:   25 DIVPKTAENFRALCTGEKG-----------FGYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYDIVKKVESL 143

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Yeast
Match: CPR3 (Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; involved in protein refolding after import into mitochondria [Source:SGD;Acc:S000004543])

HSP 1 Score: 132.88 bits (333), Expect = 1.435e-39
Identity = 66/146 (45.21%), Postives = 92/146 (63.01%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            ++VPKT ENFRA+CTGEKG             Y+   F R++P+  +QGGD     G GG+SIYG  F DE+F  KHD+ G+LSMAN G +TN SQFFIT  P  W+D ++V FG + +G + +K +E+  T + +P  +I I+E 
Sbjct:   45 NVVPKTAENFRALCTGEKG-----------WGYKGVPFHRIIPDFMIQGGDTDLTNGFGGKSIYGSKFADENFVKKHDKAGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVTKGMDIVKAIESYGTASGKPRAEIVIEEA 179

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Yeast
Match: CPR5 (Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the ER; catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; transcriptionally induced in response to unfolded proteins in the ER; CPR5 has a paralog, CPR2, that arose from the whole genome duplication [Source:SGD;Acc:S000002712])

HSP 1 Score: 123.25 bits (308), Expect = 2.105e-35
Identity = 61/144 (42.36%), Postives = 92/144 (63.89%), Query Frame = 1

Query:   10 PKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNER-PIKDIKIKET 438
            P+T ENF  +      +          + Y N+IF R++PN  +QGGD  +  G GG+SI+G TF+DE+F +KHD+ G LSMANRG++TN SQFFIT  P  W+D ++V FG +++G + +  +E VKT +   P+K++ I E+
Sbjct:   60 PQTVENFYQLTISRDPK----------MGYLNSIFHRVIPNFMIQGGDFTHRSGIGGKSIFGNTFKDENFDVKHDKPGRLSMANRGKNTNGSQFFITTVPCPWLDGKHVVFGEVLDGMDVVHYIENVKTDSRNMPVKEVIIVES 193

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Yeast
Match: CPR2 (Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; potential role in the secretory pathway; seamless-GFP and mCherry fusion proteins localize to the vacuole, while SWAT-GFP fusion localizes to both the endoplasmic reticulum and vacuole; suppresses toxicity of slow-folding human Z-type alpha1-antitrypsin variant associated with liver cirrhosis and emphysema [Source:SGD;Acc:S000001099])

HSP 1 Score: 117.472 bits (293), Expect = 2.554e-33
Identity = 61/155 (39.35%), Postives = 93/155 (60.00%), Query Frame = 1

Query:    4 IVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLA-PGSWMDTRYVAFGSIIEGSETLKKMEAV-KTVNERPIKDIKIKETKFVEPRLA 462
            + PKT +NF  + T    +            +  + F R++PN  +QGGD   G G GG+SIYG TF DE+F +KHDR+G LSMANRG+ TN SQFFIT     SW+D ++V FG +++G + +  ++ V +  N++P++ +KI +     P L+
Sbjct:   60 VCPKTAKNFYKLSTTTNSKK----------GFIGSTFHRVIPNFMVQGGDFTDGTGVGGKSIYGDTFPDENFTLKHDRKGRLSMANRGKDTNGSQFFITTTEEASWLDGKHVVFGQVVDGMDVVNYIQHVSRDANDKPLEAVKIAKCGEWTPELS 204

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Yeast
Match: CPR6 (Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; plays a role in determining prion variants; binds to Hsp82p and contributes to chaperone activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004206])

HSP 1 Score: 119.783 bits (299), Expect = 1.175e-32
Identity = 61/147 (41.50%), Postives = 88/147 (59.86%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKME--AVKTVNERPIKDIKIKE 435
            DIVPKT ENF  +C G  G ++        L Y+ +IF R++ +   Q GD     G+GGESIY   FEDE+F +KHD+  +LSMAN G +TN SQ FIT  P   +D ++V FG +I+G   ++ +E       N +P++D+KI +
Sbjct:   27 DIVPKTAENFLKLCEGNAGMAKTKP--DVPLSYKGSIFHRVIKDFMCQFGDFTNFNGTGGESIYDEKFEDENFTVKHDKPFLLSMANAGPNTNGSQAFITCVPTPHLDGKHVVFGEVIQGKRIVRLIENQQCDQENNKPLRDVKIDD 171

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Nematostella
Match: EDO41091 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5B9])

HSP 1 Score: 146.747 bits (369), Expect = 3.457e-43
Identity = 78/152 (51.32%), Postives = 107/152 (70.39%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGES-RHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEP 453
            D +P+TC NF+++  G   ES RH+      L Y+++I   +VPNGW+QGGDI  GRG GGES+YGP FEDE F++ H+RRG++ MAN+GRHTN SQF+ITL P  WMDT+YVAFG +IEG   L  +E  +T NERP  + ++ +   ++P
Sbjct:  146 DRLPRTCGNFKSLIAGNLEESERHDP--PLKLRYKDSILHGIVPNGWIQGGDIEGGRGIGGESVYGPLFEDEDFSVAHNRRGVVGMANKGRHTNGSQFYITLQPAPWMDTKYVAFGQVIEGLNVLDVLEGQETFNERPKVECRVADCGVLDP 295

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BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Nematostella
Match: EDO48915 (Peptidyl-prolyl cis-trans isomerase [Source:UniProtKB/TrEMBL;Acc:A7RHU5])

HSP 1 Score: 142.895 bits (359), Expect = 3.127e-42
Identity = 73/145 (50.34%), Postives = 98/145 (67.59%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNE--RPIKDIKI 429
            D+ PKTCENFRA+CTGE G  ++       LHY+ + F R+V +  +QGGD   G G+GGESIYG TF DE F  KH+R  +LSMANRG +TN SQFFIT  P   +D  +V FG +I+G E ++++E++ T NE  RP  D+K+
Sbjct:   34 DVCPKTCENFRALCTGECGVGKNTGKP---LHYKGSPFHRVVKDFMIQGGDFSSGNGTGGESIYGGTFGDECFEFKHERPMLLSMANRGPNTNGSQFFITTQPAPHLDNIHVVFGHVIQGEELVRQIESLPT-NEKNRPNADVKV 174

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Nematostella
Match: EDO31539 (Peptidyl-prolyl cis-trans isomerase [Source:UniProtKB/TrEMBL;Acc:A7SXN2])

HSP 1 Score: 132.88 bits (333), Expect = 2.485e-39
Identity = 67/146 (45.89%), Postives = 92/146 (63.01%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKET 438
            D+VPKT ENFRA+CTGEKG             Y+ + F R++P    QGGD   G G+GG+SIYG  F DE+F +KH   GILSMAN G  TN SQFF+  A  SW+D ++V FGS+ +G + +KK+E V + + +  K + I ++
Sbjct:   26 DVVPKTAENFRALCTGEKG-----------FGYKGSSFHRVIPGFMCQGGDFTRGDGTGGKSIYGAKFADENFNLKHTGPGILSMANAGPGTNGSQFFLCTAKTSWLDGKHVVFGSVKDGMDVVKKIEKVGSDSGKTSKKVVIADS 160

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Nematostella
Match: EDO41747 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3C4])

HSP 1 Score: 133.265 bits (334), Expect = 2.255e-37
Identity = 68/151 (45.03%), Postives = 91/151 (60.26%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEP 453
            D VPKT ENFRA+CTGEKG           LHY+   F R++ +  +QGGD     G+GGESIYG  F DE F  KHD+ G+LSMAN G +TN SQFFIT  P   +D R+V FG +++G + ++++EA    +  P     I+E   + P
Sbjct:   39 DKVPKTAENFRALCTGEKGIGPSTGKP---LHYKGCPFHRIIKDFMVQGGDFSNKNGTGGESIYGEKFADEDFTYKHDKPGLLSMANSGPNTNGSQFFITTVPTPHLDGRHVVFGKVLKGMDVVRELEATPVDDSSPKSPCIIEECGELAP 186

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Nematostella
Match: EDO34613 (Peptidyl-prolyl cis-trans isomerase [Source:UniProtKB/TrEMBL;Acc:A7SNV5])

HSP 1 Score: 128.257 bits (321), Expect = 4.421e-37
Identity = 64/145 (44.14%), Postives = 94/145 (64.83%), Query Frame = 1

Query:    7 VPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVN-ERPIKDIKIKET 438
            VPKT ENF  + TGEKG             Y+N+IF R++ +  +QGGD   G G+GG+SIYG  F DE+F ++H   G LSMAN G+ TN SQFFIT     W+D R+V FG +++G + ++K+E  KT + +RP+K++K+ ++
Sbjct:   52 VPKTAENFFQLATGEKG-----------FGYKNSIFHRVIQDFMIQGGDFTKGDGTGGKSIYGQKFADENFKLQHYGAGWLSMANAGKDTNGSQFFITTVKTPWLDGRHVVFGKVLKGMDVVRKIEKSKTDHGDRPVKEVKVADS 185

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Medaka
Match: ppil6 (peptidylprolyl isomerase like 6 [Source:NCBI gene;Acc:101164021])

HSP 1 Score: 173.326 bits (438), Expect = 4.828e-53
Identity = 82/152 (53.95%), Postives = 104/152 (68.42%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYG-RGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEP 453
            D+ PKT +NF A+CTGE G+S+        L Y+  +F R+VPNGW+Q GDI  G +G+GGESIYGPTFEDE FAI H +RGIL MAN+G H+N SQF+ITL P  WMD  YV FG ++EG + LKK+E   T NERP  + +I      +P
Sbjct:  149 DVCPKTSKNFEALCTGECGQSQSG----LQLCYKGCLFHRIVPNGWVQAGDISPGSKGNGGESIYGPTFEDECFAISHSKRGILGMANKGPHSNGSQFYITLQPTPWMDKTYVGFGQVVEGFDVLKKLEEAPTCNERPKFECRIAACGLFKP 296

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Medaka
Match: PPIG (peptidylprolyl isomerase G [Source:NCBI gene;Acc:101158399])

HSP 1 Score: 147.132 bits (370), Expect = 1.975e-40
Identity = 73/144 (50.69%), Postives = 97/144 (67.36%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKT-VNERPIKDIKI 429
            D+ PKTCENFR +CTGEKG  +  +     LHY+ ++F R+V +  +QGGD   G G GGESIYG  FEDESFA+KH++  +LSMANRG+ TN SQFFIT  P   +D  +V FG ++ G E ++ ME  KT  + RP  ++KI
Sbjct:   30 DVCPKTCENFRCLCTGEKGIGKGTQKP---LHYKGSVFHRIVKDFMIQGGDFSEGNGRGGESIYGGFFEDESFAMKHNKDLLLSMANRGKDTNGSQFFITTKPAPHLDGVHVVFGQVVSGQEVVQTMENQKTDPSSRPYAEVKI 170

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Medaka
Match: si:ch1073-55a19.2 (RANBP2-like and GRIP domain-containing protein 8 [Source:NCBI gene;Acc:101160447])

HSP 1 Score: 141.354 bits (355), Expect = 3.212e-38
Identity = 74/144 (51.39%), Postives = 95/144 (65.97%), Query Frame = 1

Query:    4 IVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            IVPKT ENFRA+CTGEKG         F L  QN+IF R+VP+   QGGDI    G+GG+SIYG +FEDE+F ++H   GILSMANRGR TN SQFFITL     +D ++VAFG + +G + +++M  + T    P K + I E
Sbjct: 2971 IVPKTAENFRALCTGEKG---------FGL--QNSIFHRVVPDFMCQGGDITNSNGTGGKSIYGSSFEDENFDVRHTGPGILSMANRGRDTNNSQFFITLKKAEHLDFKHVAFGWVRDGMDVVQQMGELGTKQGVPSKKLVITE 3103

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Medaka
Match: si:ch1073-55a19.2 (RANBP2-like and GRIP domain-containing protein 8 [Source:NCBI gene;Acc:101160447])

HSP 1 Score: 141.354 bits (355), Expect = 3.214e-38
Identity = 74/144 (51.39%), Postives = 95/144 (65.97%), Query Frame = 1

Query:    4 IVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            IVPKT ENFRA+CTGEKG         F L  QN+IF R+VP+   QGGDI    G+GG+SIYG +FEDE+F ++H   GILSMANRGR TN SQFFITL     +D ++VAFG + +G + +++M  + T    P K + I E
Sbjct: 2998 IVPKTAENFRALCTGEKG---------FGL--QNSIFHRVVPDFMCQGGDITNSNGTGGKSIYGSSFEDENFDVRHTGPGILSMANRGRDTNNSQFFITLKKAEHLDFKHVAFGWVRDGMDVVQQMGELGTKQGVPSKKLVITE 3130

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Medaka
Match: ppiaa (peptidyl-prolyl cis-trans isomerase [Source:NCBI gene;Acc:101156984])

HSP 1 Score: 125.561 bits (314), Expect = 3.919e-36
Identity = 63/143 (44.06%), Postives = 88/143 (61.54%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKI 429
            D+VPKT ENFRA+CTGEKG             Y+ + F R++P    QGGD     G+GG+SIYG  F DE+F + H   GILSMAN G +TN SQFFI     +W+D ++V FG ++EG + ++KME++ + + +    I I
Sbjct:   27 DVVPKTAENFRALCTGEKG-----------FGYKGSGFHRVIPRFMCQGGDFTNHNGTGGKSIYGNKFADENFTLTHTGPGILSMANAGPNTNGSQFFICTEKTAWLDGKHVVFGQVVEGMDVVRKMESLGSQSGKTSAKITI 158

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Planmine SMEST
Match: SMESG000059112.1 (SMESG000059112.1)

HSP 1 Score: 331.257 bits (848), Expect = 2.729e-115
Identity = 157/159 (98.74%), Postives = 158/159 (99.37%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVEPRLAETNNA 477
            DIVPKTCENFRA+CTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETK VEPRLAETNNA
Sbjct:  142 DIVPKTCENFRALCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKVVEPRLAETNNA 300

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Planmine SMEST
Match: SMESG000052204.1 (SMESG000052204.1)

HSP 1 Score: 134.42 bits (337), Expect = 1.189e-39
Identity = 66/143 (46.15%), Postives = 93/143 (65.03%), Query Frame = 1

Query:    7 VPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            VPKT ENFRA+CTGEKG             ++ + F R++PN  LQGGD   G G+GG+SIYG  FEDE+F IKH + G+LSMAN G +TN SQFFIT    +W+D ++V FG + EG + ++K+E + + + +  K + I +
Sbjct:   27 VPKTVENFRALCTGEKG-----------FGFKGSKFHRVIPNFMLQGGDFTRGNGTGGKSIYGEKFEDENFKIKHTKPGLLSMANAGPNTNGSQFFITTVITNWLDGKHVVFGEVAEGMDIVQKVEKLGSASGKTSKTVSITD 158

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Planmine SMEST
Match: SMESG000006567.1 (SMESG000006567.1)

HSP 1 Score: 129.798 bits (325), Expect = 8.441e-38
Identity = 65/145 (44.83%), Postives = 91/145 (62.76%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            D +PKT +NFRA+CTGEKG             Y+ + F R++ +  LQGGD   G G+GG+SIYG  F+DESF  KH + G+LSMAN G +TN SQFFIT     W+D ++V FG + EG E +K +E + + + +P K + I +
Sbjct:   31 DDIPKTADNFRALCTGEKG-----------FGYKGSKFHRIISSFMLQGGDFTRGNGTGGKSIYGEKFDDESFKYKHTKPGLLSMANAGPNTNGSQFFITTVVTKWLDGKHVVFGEVEEGMEIVKAIEKLGSDSGKPSKSVVIDD 164

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Planmine SMEST
Match: SMESG000006567.1 (SMESG000006567.1)

HSP 1 Score: 129.413 bits (324), Expect = 9.630e-38
Identity = 65/145 (44.83%), Postives = 91/145 (62.76%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKE 435
            D +PKT +NFRA+CTGEKG             Y+ + F R++ +  LQGGD   G G+GG+SIYG  F+DESF  KH + G+LSMAN G +TN SQFFIT     W+D ++V FG + EG E +K +E + + + +P K + I +
Sbjct:   24 DDIPKTADNFRALCTGEKG-----------FGYKGSKFHRIISSFMLQGGDFTRGNGTGGKSIYGEKFDDESFKYKHTKPGLLSMANAGPNTNGSQFFITTVVTKWLDGKHVVFGEVEEGMEIVKAIEKLGSDSGKPSKSVVIDD 157

[Close]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Planmine SMEST
Match: SMESG000079132.1 (SMESG000079132.1)

HSP 1 Score: 124.405 bits (311), Expect = 9.390e-36
Identity = 62/144 (43.06%), Postives = 91/144 (63.19%), Query Frame = 1

Query:    1 DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIK 432
            DI PKTCENFR +CTGEKG             Y+N+    +VP   + GGDI  G G+GG+SIYG TFEDE+F +KH + G+++M ++  ++N SQFFITL     ++ + V FG I+EG E ++ +E   + + +  K+IKI+
Sbjct:   26 DICPKTCENFRCLCTGEKG-----------FGYKNSKIHAVVPGSLVIGGDITKGDGTGGKSIYGETFEDENFRMKHTQPGMIAMVSKEPNSNNSQFFITLNAAKELNGKSVVFGKIVEGLEVVRFLEVFGSPDGKTKKEIKIR 158

The following BLAST results are available for this feature:

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Human
BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Celegans
BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Fly
BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Zebrafish
BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Xenopus
BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Mouse
BLAST of Peptidyl-prolyl cis-trans isomerase vs. UniProt/SwissProt
BLAST of Peptidyl-prolyl cis-trans isomerase vs. TrEMBL
BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Cavefish
BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Sea Lamprey
BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Yeast
BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Nematostella
BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Medaka
BLAST of Peptidyl-prolyl cis-trans isomerase vs. Planmine SMEST

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PPIL6	7.193e-57	55.48	peptidylprolyl isomerase like 6 [Source:HGNC Symbo...	[more]
PPIL6	2.256e-56	55.48	peptidylprolyl isomerase like 6 [Source:HGNC Symbo...	[more]
PPIL6	1.363e-50	47.09	peptidylprolyl isomerase like 6 [Source:HGNC Symbo...	[more]
PPIG	2.107e-43	49.31	peptidylprolyl isomerase G [Source:HGNC Symbol;Acc...	[more]
PPIG	5.228e-42	49.31	peptidylprolyl isomerase G [Source:HGNC Symbol;Acc...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cyn-3	1.779e-40	44.83	Peptidyl-prolyl cis-trans isomerase 3 [Source:Uni...	[more]
cyn-7	1.045e-38	44.83	Peptidyl-prolyl cis-trans isomerase 7 [Source:Uni...	[more]
cyn-7	1.045e-38	44.83	Peptidyl-prolyl cis-trans isomerase 7 [Source:Uni...	[more]
cyn-1	4.140e-38	44.83	Peptidyl-prolyl cis-trans isomerase 1 [Source:Uni...	[more]
cyn-13	1.421e-36	42.38	Peptidyl-prolyl cis-trans isomerase [Source:UniPr...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Moca-cyp	3.014e-39	50.69	gene:FBgn0039581 transcript:FBtr0085286	[more]
Cyp1	4.866e-39	45.21	gene:FBgn0004432 transcript:FBtr0074238	[more]
CG7768	1.981e-37	43.45	gene:FBgn0036415 transcript:FBtr0075736	[more]
CG7768	1.981e-37	43.45	gene:FBgn0036415 transcript:FBtr0075737	[more]
cyp33	2.006e-33	43.36	gene:FBgn0028382 transcript:FBtr0086945	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ppil6	1.200e-59	61.11	peptidylprolyl isomerase (cyclophilin)-like 6 [Sou...	[more]
ppid	4.546e-40	47.95	peptidylprolyl isomerase D [Source:ZFIN;Acc:ZDB-GE...	[more]
ppifb	8.816e-40	47.59	peptidylprolyl isomerase Fb [Source:ZFIN;Acc:ZDB-G...	[more]
ppig	3.448e-39	50.00	peptidylprolyl isomerase G (cyclophilin G) [Source...	[more]
RANBP2	3.622e-37	47.18	si:ch1073-55a19.2 [Source:ZFIN;Acc:ZDB-GENE-081104...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PPIL6	1.095e-56	55.63	peptidylprolyl isomerase like 6 [Source:NCBI gene;...	[more]
PPIL6	1.095e-56	55.63	peptidylprolyl isomerase like 6 [Source:NCBI gene;...	[more]
ppia	1.166e-38	46.15	peptidylprolyl isomerase A (cyclophilin A) [Source...	[more]
ppig	6.130e-38	47.59	peptidylprolyl isomerase G (cyclophilin G) [Source...	[more]
neurl4	1.592e-37	44.52	neuralized E3 ubiquitin protein ligase 4 [Source:X...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ppil6	6.852e-52	53.42	peptidylprolyl isomerase (cyclophilin)-like 6 [Sou...	[more]
Ppig	4.951e-40	49.31	peptidyl-prolyl isomerase G (cyclophilin G) [Sourc...	[more]
Ppig	4.951e-40	49.31	peptidyl-prolyl isomerase G (cyclophilin G) [Sourc...	[more]
Ppil6	3.146e-38	43.15	peptidylprolyl isomerase (cyclophilin)-like 6 [Sou...	[more]
Ppid	5.374e-38	48.97	peptidylprolyl isomerase D (cyclophilin D) [Source...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8IXY8\|PPIL6_HUMAN	1.083e-55	55.48	Probable inactive peptidyl-prolyl cis-trans isomer...	[more]
sp\|Q1RMP7\|PPIL6_BOVIN	2.493e-51	53.85	Probable inactive peptidyl-prolyl cis-trans isomer...	[more]
sp\|P0C1I1\|PPID_RHIO9	6.369e-43	49.65	Peptidyl-prolyl cis-trans isomerase D OS=Rhizopus ...	[more]
sp\|Q9TW32\|PPIB_DICDI	1.485e-42	50.00	Peptidyl-prolyl cis-trans isomerase B OS=Dictyoste...	[more]
sp\|Q9SKQ0\|CP19B_ARATH	2.525e-41	47.59	Peptidyl-prolyl cis-trans isomerase CYP19-2 OS=Ara...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5J4NBN4	5.185e-74	70.39	Peptidyl-prolyl cis-trans isomerase OS=Paragonimus...	[more]
A0A4E0R9D1	2.379e-72	67.95	Peptidyl-prolyl cis-trans isomerase OS=Fasciola he...	[more]
A0A504Y8P7	2.458e-72	67.95	Peptidyl-prolyl cis-trans isomerase OS=Fasciola gi...	[more]
A0A419PPI0	7.035e-70	69.08	Peptidyl-prolyl cis-trans isomerase OS=Clonorchis ...	[more]
A0A4S2LKQ6	9.077e-70	68.42	Peptidyl-prolyl cis-trans isomerase OS=Opisthorchi...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ppil6	3.732e-58	56.58	peptidylprolyl isomerase like 6 [Source:NCBI gene;...	[more]
ENSAMXT00000043946.1	3.975e-40	47.18	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000049365.1	5.710e-40	47.18	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000033420.1	7.698e-40	47.18	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000048079.1	8.738e-40	47.18	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000010135.1	1.033e-41	46.21	pep scaffold:Pmarinus_7.0:GL476417:32947:40880:1 g...	[more]
ppig	2.416e-40	50.00	peptidylprolyl isomerase G (cyclophilin G) [Source...	[more]
ppifb	7.703e-38	49.23	peptidylprolyl isomerase Fb [Source:ZFIN;Acc:ZDB-G...	[more]
ENSPMAT00000004654.1	2.192e-35	43.84	pep scaffold:Pmarinus_7.0:GL489343:42315:43690:-1 ...	[more]
ENSPMAT00000004873.1	2.193e-30	56.00	pep scaffold:Pmarinus_7.0:GL486356:449:3367:-1 gen...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
CPR1	2.773e-41	50.77	Cytoplasmic peptidyl-prolyl cis-trans isomerase (c...	[more]
CPR3	1.435e-39	45.21	Mitochondrial peptidyl-prolyl cis-trans isomerase ...	[more]
CPR5	2.105e-35	42.36	Peptidyl-prolyl cis-trans isomerase (cyclophilin) ...	[more]
CPR2	2.554e-33	39.35	Peptidyl-prolyl cis-trans isomerase (cyclophilin);...	[more]
CPR6	1.175e-32	41.50	Peptidyl-prolyl cis-trans isomerase (cyclophilin);...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO41091	3.457e-43	51.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48915	3.127e-42	50.34	Peptidyl-prolyl cis-trans isomerase [Source:UniPr...	[more]
EDO31539	2.485e-39	45.89	Peptidyl-prolyl cis-trans isomerase [Source:UniPr...	[more]
EDO41747	2.255e-37	45.03	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34613	4.421e-37	44.14	Peptidyl-prolyl cis-trans isomerase [Source:UniPr...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ppil6	4.828e-53	53.95	peptidylprolyl isomerase like 6 [Source:NCBI gene;...	[more]
PPIG	1.975e-40	50.69	peptidylprolyl isomerase G [Source:NCBI gene;Acc:1...	[more]
si:ch1073-55a19.2	3.212e-38	51.39	RANBP2-like and GRIP domain-containing protein 8 [...	[more]
si:ch1073-55a19.2	3.214e-38	51.39	RANBP2-like and GRIP domain-containing protein 8 [...	[more]
ppiaa	3.919e-36	44.06	peptidyl-prolyl cis-trans isomerase [Source:NCBI g...	[more]

BLAST of Peptidyl-prolyl cis-trans isomerase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000059112.1	2.729e-115	98.74	SMESG000059112.1	[more]
SMESG000052204.1	1.189e-39	46.15	SMESG000052204.1	[more]
SMESG000006567.1	8.441e-38	44.83	SMESG000006567.1	[more]
SMESG000006567.1	9.630e-38	44.83	SMESG000006567.1	[more]
SMESG000079132.1	9.390e-36	43.06	SMESG000079132.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30006859 ID=SMED30006859|Name=Peptidyl-prolyl cis-trans isomerase|organism=Schmidtea mediterranea sexual|type=transcript|length=666bp
GATATTGTTCCGAAGACATGCGAAAATTTCCGTGCAGTGTGTACTGGAGA
AAAGGGTGAATCAAGACACAATGAAGTGGAGACCTTTAACTTGCACTATC
AAAATACTATATTTTTTCGTCTGGTCCCCAATGGATGGTTACAAGGAGGA
GATATTTGGTATGGACGTGGAAGTGGTGGCGAATCTATTTATGGTCCCAC
ATTCGAAGATGAAAGTTTTGCTATAAAGCATGACAGACGTGGCATTCTTA
GCATGGCCAACAGGGGAAGGCATACTAATCAGTCTCAATTTTTCATAACT
CTTGCTCCAGGCTCATGGATGGACACTCGCTACGTAGCATTTGGATCTAT
AATTGAAGGAAGTGAAACTCTGAAGAAAATGGAAGCAGTAAAAACTGTCA
ATGAGAGACCGATAAAAGATATCAAAATAAAAGAAACAAAATTTGTTGAA
CCCAGGCTAGCTGAAACCAATAATGCATGATTTTTCAGATTTATTAATAA
TTATGTTTTTATTTATTTATCATTTTAATGTTGATGAAATAAAGTAAGAT
TTTGTTAAAAGTGACCTTCGATTTTACCATTGTAAAAAGTTTGAATAATC
CTGAAAAAAAGCAAAAACTGTAATGAGTATATCGGTTCAAATAAACCATT
ATGTTGCAAAAAAAAA

protein sequence of SMED30006859-orf-1

>SMED30006859-orf-1 ID=SMED30006859-orf-1|Name=SMED30006859-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=160bp
DIVPKTCENFRAVCTGEKGESRHNEVETFNLHYQNTIFFRLVPNGWLQGG
DIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFIT
LAPGSWMDTRYVAFGSIIEGSETLKKMEAVKTVNERPIKDIKIKETKFVE
PRLAETNNA*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0000418	head
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR002130	Cyclophilin-type_PPIase_dom
IPR029000	Cyclophilin-like_dom_sf
IPR024936	Cyclophilin-type_PPIase

Vocabulary: **molecular function**
Term	Definition
GO:0003755	peptidyl-prolyl cis-trans isomerase activity
GO:0016853	isomerase activity

Vocabulary: **biological process**
Term	Definition
GO:0006457	protein folding
GO:0000413	protein peptidyl-prolyl isomerization

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002130	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain	PRINTS	PR00153	CSAPPISMRASE	coord: 38..50 score: 45.74 coord: 81..96 score: 67.34 coord: 96..108 score: 52.36 coord: 109..124 score: 30.43
IPR002130	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain	PFAM	PF00160	Pro_isomerase	coord: 2..148 e-value: 1.9E-36 score: 125.7
IPR002130	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain	PROSITE	PS50072	CSA_PPIASE_2	coord: 1..148 score: 30.86
IPR029000	Cyclophilin-like domain superfamily	GENE3D	G3DSA:2.40.100.10		coord: 1..149 e-value: 1.2E-57 score: 196.5
IPR029000	Cyclophilin-like domain superfamily	SUPERFAMILY	SSF50891	Cyclophilin-like	coord: 1..149
IPR024936	Cyclophilin-type peptidyl-prolyl cis-trans isomerase	PIRSF	PIRSF001467	Peptidylpro_ismrse	coord: 1..153 e-value: 7.1E-52 score: 173.2
None	No IPR available	PANTHER	PTHR11071	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE	coord: 1..147
None	No IPR available	PANTHER	PTHR11071:SF193	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 6	coord: 1..147