Dual specificity protein phosphatase 23

Overview
NameDual specificity protein phosphatase 23
Smed IDSMED30006824
Length (bp)843
Neoblast Clusters

Zeng et. al., 2018



 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006824

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
reproductive organSMED30006824SMESG000027214.1 SMESG000020520.1 SMESG000076404.1 Contig43045newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006824SMESG000027214.1 SMESG000020520.1 SMESG000076404.1 Contig43045uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Human
Match: DUSP23 (dual specificity phosphatase 23 [Source:HGNC Symbol;Acc:HGNC:21480])

HSP 1 Score: 98.2117 bits (243), Expect = 7.615e-25
Identity = 56/155 (36.13%), Postives = 80/155 (51.61%), Query Frame = 2 
Query:  143 IPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            + PPNFSWV+PG LA  A P L  H  FL+  GV  +++L     P SD C       P +  H   I D       ++    +++D   +R   V VHC+ G GRTG +LAC+ +    + A ++I  IR +RP S+ET  Q K ++ FY   K
Sbjct:    3 VQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSC-------PGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRTK 150
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Human
Match: DUSP23 (dual specificity phosphatase 23 [Source:HGNC Symbol;Acc:HGNC:21480])

HSP 1 Score: 98.2117 bits (243), Expect = 7.615e-25
Identity = 56/155 (36.13%), Postives = 80/155 (51.61%), Query Frame = 2 
Query:  143 IPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            + PPNFSWV+PG LA  A P L  H  FL+  GV  +++L     P SD C       P +  H   I D       ++    +++D   +R   V VHC+ G GRTG +LAC+ +    + A ++I  IR +RP S+ET  Q K ++ FY   K
Sbjct:    3 VQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSC-------PGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRTK 150
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Human
Match: DUSP23 (dual specificity phosphatase 23 [Source:HGNC Symbol;Acc:HGNC:21480])

HSP 1 Score: 98.2117 bits (243), Expect = 7.615e-25
Identity = 56/155 (36.13%), Postives = 80/155 (51.61%), Query Frame = 2 
Query:  143 IPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            + PPNFSWV+PG LA  A P L  H  FL+  GV  +++L     P SD C       P +  H   I D       ++    +++D   +R   V VHC+ G GRTG +LAC+ +    + A ++I  IR +RP S+ET  Q K ++ FY   K
Sbjct:    3 VQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSC-------PGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRTK 150
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Human
Match: PTPDC1 (protein tyrosine phosphatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30184])

HSP 1 Score: 65.855 bits (159), Expect = 1.605e-11
Identity = 45/159 (28.30%), Postives = 76/159 (47.80%), Query Frame = 2 
Query:  161 SWVIPGILAASARP----VLREHLCF-LMKEGVGAIITLYSPFSDKC-------------LPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            SWV   ILA  ARP    + + H+    +  G+  II L  P                  LP  + E  IY++     D    ++  +  + KV+ + + ++  V +HC  G GRTG+++AC+ +  T+M A ++I F+R  RP S++T  Q+  +  F
Sbjct:  138 SWVTDNILAM-ARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFAL-QEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREF 294
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Human
Match: PTPDC1 (protein tyrosine phosphatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30184])

HSP 1 Score: 65.855 bits (159), Expect = 1.619e-11
Identity = 45/159 (28.30%), Postives = 76/159 (47.80%), Query Frame = 2 
Query:  161 SWVIPGILAASARP----VLREHLCF-LMKEGVGAIITLYSPFSDKC-------------LPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            SWV   ILA  ARP    + + H+    +  G+  II L  P                  LP  + E  IY++     D    ++  +  + KV+ + + ++  V +HC  G GRTG+++AC+ +  T+M A ++I F+R  RP S++T  Q+  +  F
Sbjct:  136 SWVTDNILAM-ARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFAL-QEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREF 292
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Celegans
Match: T12B3.1 (pep chromosome:WBcel235:IV:7382415:7384752:1 gene:WBGene00020444.1 transcript:T12B3.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T12B3.1)

HSP 1 Score: 53.5286 bits (127), Expect = 6.848e-8
Identity = 24/74 (32.43%), Postives = 46/74 (62.16%), Query Frame = 2 
Query:  377 IQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            I KV+D+ +S    + VHC  G GRTG+V+A + +    M   ++++ +R+ R ++V++  Q+K ++ F L I+
Sbjct:  160 IVKVVDFALSHG-KIAVHCHAGHGRTGMVIAAWMMYALGMSPSQAVDTVRSRRAKAVQSKEQVKTLHEFRLLIR 232
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Zebrafish
Match: dusp23a (dual specificity phosphatase 23a [Source:ZFIN;Acc:ZDB-GENE-030131-2554])

HSP 1 Score: 96.2857 bits (238), Expect = 4.393e-24
Identity = 49/150 (32.67%), Postives = 83/150 (55.33%), Query Frame = 2 
Query:  140 PIPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYSPFSDKCLPPVYEE-PDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFY 586
            P  PPNFSWV P  LA  ARP +  H  +L+  G+  +++L      +  PP YE+ P++  H  +I D +  + +++     +++   ++   V VHC+ G GRTG +LAC+ +    +  +E+I  IR +R  SVET  Q + + +F+
Sbjct:    7 PAEPPNFSWVEPCKLAGLARPTMVHHYRYLLDHGIKHLVSLL-----EIKPPNYEKCPELSLHQISIVDFTPPSRSQILQFLSIVEKANAKGEGVAVHCAHGHGRTGTMLACYLVKSRHLSGEEAIKEIRRLREGSVETKEQEQAVIDFH 151
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Zebrafish
Match: dusp23a (dual specificity phosphatase 23a [Source:ZFIN;Acc:ZDB-GENE-030131-2554])

HSP 1 Score: 96.2857 bits (238), Expect = 4.393e-24
Identity = 49/150 (32.67%), Postives = 83/150 (55.33%), Query Frame = 2 
Query:  140 PIPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYSPFSDKCLPPVYEE-PDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFY 586
            P  PPNFSWV P  LA  ARP +  H  +L+  G+  +++L      +  PP YE+ P++  H  +I D +  + +++     +++   ++   V VHC+ G GRTG +LAC+ +    +  +E+I  IR +R  SVET  Q + + +F+
Sbjct:    7 PAEPPNFSWVEPCKLAGLARPTMVHHYRYLLDHGIKHLVSLL-----EIKPPNYEKCPELSLHQISIVDFTPPSRSQILQFLSIVEKANAKGEGVAVHCAHGHGRTGTMLACYLVKSRHLSGEEAIKEIRRLREGSVETKEQEQAVIDFH 151
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Zebrafish
Match: dusp23b (dual specificity phosphatase 23b [Source:ZFIN;Acc:ZDB-GENE-040718-163])

HSP 1 Score: 91.6633 bits (226), Expect = 1.504e-22
Identity = 53/149 (35.57%), Postives = 75/149 (50.34%), Query Frame = 2 
Query:  149 PPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFY 586
            PPNFSWV PG +A  A P +  H  +L+  G+  ++TL     P  D C       PD+  H   I D    T  ++     +++   +    V VHC  G GRTG +LAC+ +   K+   ++IN IR IR  S+ET  Q +MI  FY
Sbjct:    6 PPNFSWVDPGKVAGLAMPRMTAHYQYLLNNGIKHLVTLTERKPPDHDTC-------PDLTLHHIKIIDFCPPTFEQINRFLTIVEEANASGQAVAVHCLHGFGRTGTMLACYLVKSRKISGIDAINEIRRIRRGSIETREQEQMIVQFY 147
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Zebrafish
Match: BX571879.2 (pep chromosome:GRCz11:CHR_ALT_CTG18_1_3:7591744:7600733:1 gene:ENSDARG00000112511.1 transcript:ENSDART00000190620.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX571879.2)

HSP 1 Score: 67.3958 bits (163), Expect = 2.903e-12
Identity = 47/166 (28.31%), Postives = 82/166 (49.40%), Query Frame = 2 
Query:  161 SWVIPGILAASARPVLREHLCFLMKE----------GVGAIITLYSPFSDK-CLPPVYEEPD--------------IYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            SWV   ILA  ARP       +LMK            + +II +  P     C PP+  EPD              I+++   + D    ++  M    KV+ + + ++  V VHC  G GRTG+++AC+ +   ++ A E+++++R  RP S++T SQ+ ++++F
Sbjct:   59 SWVTDDILAM-ARPST-----YLMKRYSIIEQFKQLNIKSIINMQLPGEHAHCGPPL--EPDSGFTYSPQIFMDNQIFFYNFGMSDFGVSSLEGMLDAVKVLAFSV-QEGKVAVHCHAGLGRTGVLIACYLVYTCRISASEAVHYVRIKRPRSIQTRSQINLVFDF 215
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Zebrafish
Match: zgc:77752 (zgc:77752 [Source:ZFIN;Acc:ZDB-GENE-040426-1867])

HSP 1 Score: 67.3958 bits (163), Expect = 3.068e-12
Identity = 47/166 (28.31%), Postives = 82/166 (49.40%), Query Frame = 2 
Query:  161 SWVIPGILAASARPVLREHLCFLMKE----------GVGAIITLYSPFSDK-CLPPVYEEPD--------------IYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            SWV   ILA  ARP       +LMK            + +II +  P     C PP+  EPD              I+++   + D    ++  M    KV+ + + ++  V VHC  G GRTG+++AC+ +   ++ A E+++++R  RP S++T SQ+ ++++F
Sbjct:   59 SWVTDDILAM-ARPST-----YLMKRYSIIEQFKQLNIKSIINMQLPGEHAHCGPPL--EPDSGFTYSPQSFMDNQIFFYNFGMSDFGVSSLEGMLDAVKVLAFSV-QEGKVAVHCHAGLGRTGVLIACYLVYTCRISASEAVHYVRIKRPRSIQTRSQINLVFDF 215
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Xenopus
Match: mettl14 (methyltransferase like 14 [Source:Xenbase;Acc:XB-GENE-5813560])

HSP 1 Score: 101.293 bits (251), Expect = 1.611e-25
Identity = 59/156 (37.82%), Postives = 85/156 (54.49%), Query Frame = 2 
Query:  140 PIPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            P+PP NFSWV PG+LA  A P L  H  +L + G+  +ITL     P+ D C       P I  H   I D    ++ ++    K++D   ++   V VHC  G GRTG +LAC+ +   K+   ++IN IR++R  S+ETT Q K I  F+ +IK
Sbjct:   47 PVPPHNFSWVEPGLLAGMAMPRLPAHYEYLYENGIRHLITLTEHKPPYHDTC-------PGITLHRIRILDFCAPSLEQIKNFLKIVDDAKAKGEAVGVHCLHGFGRTGTMLACYLVKVRKITGVDAINEIRSLRRGSIETTEQEKAIIQFHHHIK 195
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Xenopus
Match: PTPDC1 (protein tyrosine phosphatase domain containing 1 [Source:NCBI gene;Acc:100490857])

HSP 1 Score: 56.6102 bits (135), Expect = 1.682e-8
Identity = 29/99 (29.29%), Postives = 55/99 (55.56%), Query Frame = 2 
Query:  287 LPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            LP  + E +IY++     D    ++  +  + KV+ + + ++  V +HC  G GRTG+++AC+ I  T+M A ++I  +R  R  +++T  Q+  I  F
Sbjct:  143 LPEAFMEAEIYFYNFGWKDYGVASLTTILDMVKVMAFAL-QEGKVAIHCHAGLGRTGVLIACYLIFATRMTADQAILLVRARRHNAIQTRVQLLCIREF 240
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Xenopus
Match: PTPDC1 (protein tyrosine phosphatase domain containing 1 [Source:NCBI gene;Acc:100490857])

HSP 1 Score: 56.225 bits (134), Expect = 2.072e-8
Identity = 29/99 (29.29%), Postives = 55/99 (55.56%), Query Frame = 2 
Query:  287 LPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            LP  + E +IY++     D    ++  +  + KV+ + + ++  V +HC  G GRTG+++AC+ I  T+M A ++I  +R  R  +++T  Q+  I  F
Sbjct:  157 LPEAFMEAEIYFYNFGWKDYGVASLTTILDMVKVMAFAL-QEGKVAIHCHAGLGRTGVLIACYLIFATRMTADQAILLVRARRHNAIQTRVQLLCIREF 254
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Xenopus
Match: CDC14A (cell division cycle 14A [Source:NCBI gene;Acc:100490252])

HSP 1 Score: 50.447 bits (119), Expect = 1.259e-6
Identity = 33/158 (20.89%), Postives = 67/158 (42.41%), Query Frame = 2 
Query:  134 YIPIPPPNFSWVIPGILAASARP-------------VLREHLCFLMKEGVGAIITLYSPFSD--KCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQ 562
            Y  +   +F+W++PG   A + P                 +  +  K  + A+I L     D  +     ++  D+++   +             ++++ ++   + D  + VHC  G GRTG ++AC+ + H ++   E+I +IR  RP S+    Q
Sbjct:  166 YERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFRKHNIRAVIRLNKKIYDAKRFTDAGFDHYDLFFVDGSTPSDG--------IVRRFLNLCENTDGAIAVHCKAGLGRTGTLIACYIMKHYRLTHSEAIAWIRICRPGSIIGPQQ 315
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Xenopus
Match: CDC14A (cell division cycle 14A [Source:NCBI gene;Acc:100490252])

HSP 1 Score: 50.0618 bits (118), Expect = 2.144e-6
Identity = 32/153 (20.92%), Postives = 66/153 (43.14%), Query Frame = 2 
Query:  134 YIPIPPPNFSWVIPGILAASARP-------------VLREHLCFLMKEGVGAIITLYSPFSD--KCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESV 547
            Y  +   +F+W++PG   A + P                 +  +  K  + A+I L     D  +     ++  D+++   +             ++++ ++   + D  + VHC  G GRTG ++AC+ + H ++   E+I +IR  RP S+
Sbjct:  170 YERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFRKHNIRAVIRLNKKIYDAKRFTDAGFDHYDLFFVDGSTPSDG--------IVRRFLNLCENTDGAIAVHCKAGLGRTGTLIACYIMKHYRLTHSEAIAWIRICRPGSI 314
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Mouse
Match: Dusp23 (dual specificity phosphatase 23 [Source:MGI Symbol;Acc:MGI:1915690])

HSP 1 Score: 102.834 bits (255), Expect = 1.096e-26
Identity = 57/155 (36.77%), Postives = 82/155 (52.90%), Query Frame = 2 
Query:  143 IPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            + PPNFSWV+PG LA  A P L  H  FL+ +GV  +++L     P SD C       P +  H   I D    +  ++    K++D   +R   V VHC+ G GRTG +LAC+ +    + A ++I  IR +RP S+ET  Q K ++ FY   K
Sbjct:    3 VQPPNFSWVLPGRLAGLALPRLPAHYQFLLDQGVRHLVSLTERGPPHSDSC-------PGLTLHRMRIPDFCPPSPEQIDQFVKIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERALAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRTK 150
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Mouse
Match: Ptpdc1 (protein tyrosine phosphatase domain containing 1 [Source:MGI Symbol;Acc:MGI:2145430])

HSP 1 Score: 67.0106 bits (162), Expect = 5.347e-12
Identity = 46/159 (28.93%), Postives = 77/159 (48.43%), Query Frame = 2 
Query:  161 SWVIPGILAASARP---VLREHLCF--LMKEGVGAIITLYSPFSDKC-------------LPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            SWV   ILA  ARP   +L ++      + +G+  II L  P                  LP  + E  IY++     D    ++  +  + KV+ + + ++  V VHC  G GRTG+++AC+ +  T+M A ++I F+R  RP S++T  Q+  +  F
Sbjct:  132 SWVTDNILAM-ARPSSELLEKYRIIEQFLGQGIKTIINLQRPGEHASCGSALEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTAILDMVKVMTFAL-QEGKVAVHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREF 288
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Mouse
Match: Ptpdc1 (protein tyrosine phosphatase domain containing 1 [Source:MGI Symbol;Acc:MGI:2145430])

HSP 1 Score: 66.6254 bits (161), Expect = 6.400e-12
Identity = 46/159 (28.93%), Postives = 77/159 (48.43%), Query Frame = 2 
Query:  161 SWVIPGILAASARP---VLREHLCF--LMKEGVGAIITLYSPFSDKC-------------LPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            SWV   ILA  ARP   +L ++      + +G+  II L  P                  LP  + E  IY++     D    ++  +  + KV+ + + ++  V VHC  G GRTG+++AC+ +  T+M A ++I F+R  RP S++T  Q+  +  F
Sbjct:  145 SWVTDNILAM-ARPSSELLEKYRIIEQFLGQGIKTIINLQRPGEHASCGSALEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTAILDMVKVMTFAL-QEGKVAVHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREF 301
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Mouse
Match: Ptpdc1 (protein tyrosine phosphatase domain containing 1 [Source:MGI Symbol;Acc:MGI:2145430])

HSP 1 Score: 66.6254 bits (161), Expect = 6.485e-12
Identity = 46/159 (28.93%), Postives = 77/159 (48.43%), Query Frame = 2 
Query:  161 SWVIPGILAASARP---VLREHLCF--LMKEGVGAIITLYSPFSDKC-------------LPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            SWV   ILA  ARP   +L ++      + +G+  II L  P                  LP  + E  IY++     D    ++  +  + KV+ + + ++  V VHC  G GRTG+++AC+ +  T+M A ++I F+R  RP S++T  Q+  +  F
Sbjct:   84 SWVTDNILAM-ARPSSELLEKYRIIEQFLGQGIKTIINLQRPGEHASCGSALEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTAILDMVKVMTFAL-QEGKVAVHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREF 240
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Mouse
Match: Cdc14b (CDC14 cell division cycle 14B [Source:MGI Symbol;Acc:MGI:2441808])

HSP 1 Score: 52.7582 bits (125), Expect = 1.862e-7
Identity = 34/114 (29.82%), Postives = 59/114 (51.75%), Query Frame = 2 
Query:  374 LIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIKQYYKSFKTHILDGVFKTNSLKRKFEIP--KSFSRNLFEA 709
            ++Q+ +D   +    + VHC  G GRTG ++ C+ + H +M A ESI ++R  RP SV    Q       +L +KQ      +  L+G +    L+ +   P  ++FS++L +A
Sbjct:  258 IVQEFLDICENVKGAIAVHCKAGLGRTGTLIGCYLMKHYRMTAAESIAWLRICRPGSVIGPQQQ------FLVMKQ-----SSLWLEGDYFRQKLRGQENGPLREAFSKHLSDA 360
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. UniProt/SwissProt
Match: sp|Q6NT99|DUS23_MOUSE (Dual specificity protein phosphatase 23 OS=Mus musculus OX=10090 GN=Dusp23 PE=1 SV=1)

HSP 1 Score: 102.834 bits (255), Expect = 7.665e-26
Identity = 57/155 (36.77%), Postives = 82/155 (52.90%), Query Frame = 2 
Query:  143 IPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            + PPNFSWV+PG LA  A P L  H  FL+ +GV  +++L     P SD C       P +  H   I D    +  ++    K++D   +R   V VHC+ G GRTG +LAC+ +    + A ++I  IR +RP S+ET  Q K ++ FY   K
Sbjct:    3 VQPPNFSWVLPGRLAGLALPRLPAHYQFLLDQGVRHLVSLTERGPPHSDSC-------PGLTLHRMRIPDFCPPSPEQIDQFVKIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERALAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRTK 150
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. UniProt/SwissProt
Match: sp|Q9BVJ7|DUS23_HUMAN (Dual specificity protein phosphatase 23 OS=Homo sapiens OX=9606 GN=DUSP23 PE=1 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 3.657e-24
Identity = 56/155 (36.13%), Postives = 80/155 (51.61%), Query Frame = 2 
Query:  143 IPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            + PPNFSWV+PG LA  A P L  H  FL+  GV  +++L     P SD C       P +  H   I D       ++    +++D   +R   V VHC+ G GRTG +LAC+ +    + A ++I  IR +RP S+ET  Q K ++ FY   K
Sbjct:    3 VQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSC-------PGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRTK 150
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. UniProt/SwissProt
Match: sp|A7E379|PTPC1_BOVIN (Protein tyrosine phosphatase domain-containing protein 1 OS=Bos taurus OX=9913 GN=PTPDC1 PE=2 SV=2)

HSP 1 Score: 69.3218 bits (168), Expect = 6.014e-12
Identity = 46/159 (28.93%), Postives = 76/159 (47.80%), Query Frame = 2 
Query:  161 SWVIPGILAASARPVLR--EHLCFLMK---EGVGAIITLYSPFSDKC-------------LPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            SWV   ILA  ARP     E  C + +    G+ +II L  P                  LP  + E  IY++     D    ++  +  + KV+ + + ++  V +HC  G GRTG+++AC+ +  T+M A ++I F+R  RP S++T  Q+  +  F
Sbjct:  128 SWVTDNILAM-ARPSTEVLEKFCIIEQFRSHGIKSIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFAL-QEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREF 284
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. UniProt/SwissProt
Match: sp|Q6NZK8|PTPC1_MOUSE (Protein tyrosine phosphatase domain-containing protein 1 OS=Mus musculus OX=10090 GN=Ptpdc1 PE=1 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 4.536e-11
Identity = 46/159 (28.93%), Postives = 77/159 (48.43%), Query Frame = 2 
Query:  161 SWVIPGILAASARP---VLREHLCF--LMKEGVGAIITLYSPFSDKC-------------LPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            SWV   ILA  ARP   +L ++      + +G+  II L  P                  LP  + E  IY++     D    ++  +  + KV+ + + ++  V VHC  G GRTG+++AC+ +  T+M A ++I F+R  RP S++T  Q+  +  F
Sbjct:   84 SWVTDNILAM-ARPSSELLEKYRIIEQFLGQGIKTIINLQRPGEHASCGSALEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTAILDMVKVMTFAL-QEGKVAVHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREF 240
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. UniProt/SwissProt
Match: sp|A2A3K4|PTPC1_HUMAN (Protein tyrosine phosphatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PTPDC1 PE=1 SV=1)

HSP 1 Score: 65.855 bits (159), Expect = 7.835e-11
Identity = 45/159 (28.30%), Postives = 76/159 (47.80%), Query Frame = 2 
Query:  161 SWVIPGILAASARP----VLREHLCF-LMKEGVGAIITLYSPFSDKC-------------LPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            SWV   ILA  ARP    + + H+    +  G+  II L  P                  LP  + E  IY++     D    ++  +  + KV+ + + ++  V +HC  G GRTG+++AC+ +  T+M A ++I F+R  RP S++T  Q+  +  F
Sbjct:   84 SWVTDNILAM-ARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFAL-QEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREF 240
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. TrEMBL
Match: A0A2Y9FV54 (dual specificity protein phosphatase 23 OS=Physeter macrocephalus OX=9755 GN=DUSP23 PE=4 SV=1)

HSP 1 Score: 101.679 bits (252), Expect = 5.947e-23
Identity = 57/155 (36.77%), Postives = 81/155 (52.26%), Query Frame = 2 
Query:  143 IPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            + PPNFSWV+PG LA  A P L  H  FL+ +GV  +++L     P SD C       P +  H   I D       ++    K++D   +R   V VHC+ G GRTG +LAC+ +    + A ++I  IR +RP S+ET  Q K ++ FY   K
Sbjct:    3 VQPPNFSWVLPGRLAGLALPRLPAHYQFLLDQGVRHLVSLTERRPPHSDSC-------PSLTLHRLRIPDFCSPGPEQIDRFLKIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRRK 150
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. TrEMBL
Match: D3ZRL3 (Dual-specificity phosphatase 23 OS=Rattus norvegicus OX=10116 GN=Dusp23 PE=1 SV=1)

HSP 1 Score: 101.679 bits (252), Expect = 6.541e-23
Identity = 58/155 (37.42%), Postives = 80/155 (51.61%), Query Frame = 2 
Query:  143 IPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            + PPNFSWV+PG LA  A P L  H  FL+  GV  +++L     P SD C       P +  H   I D       ++    K++D   +R   V VHC+ G GRTG +LAC+ +    + A E+I  IR +RP S+ET  Q K ++ FY   K
Sbjct:    3 VQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSC-------PGLTLHRLRIPDFCPPAPEQIDQFVKIVDEANARGEAVGVHCALGFGRTGTMLACYLVKEQGLAAGEAIAEIRRLRPGSIETYEQEKAVFQFYQRTK 150
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. TrEMBL
Match: A0A2Y9M0R4 (dual specificity protein phosphatase 23 OS=Delphinapterus leucas OX=9749 GN=DUSP23 PE=4 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 7.504e-23
Identity = 57/155 (36.77%), Postives = 81/155 (52.26%), Query Frame = 2 
Query:  143 IPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            + PPNFSWV+PG LA  A P L  H  FL+ +GV  +++L     P SD C       P +  H   I D       ++    K++D   +R   V VHC+ G GRTG +LAC+ +    + A ++I  IR +RP S+ET  Q K ++ FY   K
Sbjct:    3 VQPPNFSWVLPGRLAGLALPRLPAHYQFLLDQGVRHLVSLTERGPPHSDSC-------PGLTLHRLRIPDFCSPGPEQIDRFVKIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRRK 150
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. TrEMBL
Match: A0A383ZAE5 (dual specificity protein phosphatase 23 OS=Balaenoptera acutorostrata scammoni OX=310752 GN=DUSP23 PE=4 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 7.504e-23
Identity = 57/155 (36.77%), Postives = 81/155 (52.26%), Query Frame = 2 
Query:  143 IPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            + PPNFSWV+PG LA  A P L  H  FL+ +GV  +++L     P SD C       P +  H   I D       ++    K++D   +R   V VHC+ G GRTG +LAC+ +    + A ++I  IR +RP S+ET  Q K ++ FY   K
Sbjct:    3 VQPPNFSWVLPGRLAGLALPRLPAHYQFLLDQGVRHLVSLTERGPPHSDSC-------PGLTLHRLRIPDFCSPGPEQIDRFVKIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRRK 150
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. TrEMBL
Match: A0A341BX30 (dual specificity protein phosphatase 23 isoform X1 OS=Neophocaena asiaeorientalis asiaeorientalis OX=1706337 GN=DUSP23 PE=4 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 7.504e-23
Identity = 57/155 (36.77%), Postives = 81/155 (52.26%), Query Frame = 2 
Query:  143 IPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            + PPNFSWV+PG LA  A P L  H  FL+ +GV  +++L     P SD C       P +  H   I D       ++    K++D   +R   V VHC+ G GRTG +LAC+ +    + A ++I  IR +RP S+ET  Q K ++ FY   K
Sbjct:    3 VQPPNFSWVLPGRLAGLALPRLPAHYQFLLDQGVRHLVSLTERGPPHSDSC-------PGLTLHRLRIPDFCSPGPEQIDRFVKIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRRK 150
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Cavefish
Match: dusp23b (dual specificity protein phosphatase 23-like [Source:NCBI gene;Acc:103035756])

HSP 1 Score: 88.9669 bits (219), Expect = 1.421e-21
Identity = 52/153 (33.99%), Postives = 77/153 (50.33%), Query Frame = 2 
Query:  149 PPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            P NFSWV P  LA  A P +  H  +L+  G+  ++TL     P+ D C       P++  H   I D    T  ++     +++   ++   V VHC  G GRTG +LAC+ +   K+   ++IN IR IR  S+ET  Q +M+  FY  IK
Sbjct:    6 PHNFSWVEPHKLAGLAMPRMPGHYQYLVNNGIKHLVTLSERKPPYHDTC-------PELTLHHIRIHDFCAPTFDQIKRFLTIVEEANTKGEGVAVHCLHGYGRTGTMLACYLVKSRKLSGIDAINEIRRIRHGSIETREQEQMVVQFYQQIK 151
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Cavefish
Match: dusp23b (dual specificity protein phosphatase 23-like [Source:NCBI gene;Acc:103035756])

HSP 1 Score: 87.8113 bits (216), Expect = 1.132e-20
Identity = 52/153 (33.99%), Postives = 77/153 (50.33%), Query Frame = 2 
Query:  149 PPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            P NFSWV P  LA  A P +  H  +L+  G+  ++TL     P+ D C       P++  H   I D    T  ++     +++   ++   V VHC  G GRTG +LAC+ +   K+   ++IN IR IR  S+ET  Q +M+  FY  IK
Sbjct:   55 PHNFSWVEPHKLAGLAMPRMPGHYQYLVNNGIKHLVTLSERKPPYHDTC-------PELTLHHIRIHDFCAPTFDQIKRFLTIVEEANTKGEGVAVHCLHGYGRTGTMLACYLVKSRKLSGIDAINEIRRIRHGSIETREQEQMVVQFYQQIK 200
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Cavefish
Match: ENSAMXT00000043439.1 (dual specificity protein phosphatase 23-like [Source:NCBI gene;Acc:103032688])

HSP 1 Score: 81.2629 bits (199), Expect = 1.606e-18
Identity = 51/154 (33.12%), Postives = 76/154 (49.35%), Query Frame = 2 
Query:  146 PPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYS---PFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMI--YNFYLN 592
            PPPNFSWV    LA  A P    H  FL++  +  ++ L     P S+ C       P +  H   I D +  ++A++     +++   SR   V VHC  G GRTG +LAC+ +    +   E+I  IR +RP S+ET  Q + +  Y  YL+
Sbjct:    7 PPPNFSWVQADRLAGLAWPSRPAHYRFLLQNRIQHLVCLCESKPPGSESC-------PALTLHHIPIVDFTPPSLAQIQSFLSIVEDSSSRGEGVGVHCMHGHGRTGTMLACYLVKTRNISGLEAIEEIRKLRPGSIETKDQEQAVIKYQHYLH 153
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Cavefish
Match: zgc:77752 (protein tyrosine phosphatase domain-containing protein 1-like [Source:NCBI gene;Acc:103032733])

HSP 1 Score: 68.5514 bits (166), Expect = 9.776e-13
Identity = 32/98 (32.65%), Postives = 59/98 (60.20%), Query Frame = 2 
Query:  290 PPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            P V+ E  IY++   + D    +I  M    KV+ + +  +  V VHC  G GRTG+++AC+ I   ++ A E+I+++R  RP S++T +Q+ ++++F
Sbjct:  113 PQVFMENQIYFYNFGMTDFGVSSIVGMLDAVKVLTFSV-EEGKVAVHCHAGLGRTGVLIACYLIYMLRITASEAIHYVRIKRPRSIQTRAQISLVFDF 209
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Cavefish
Match: zgc:77752 (protein tyrosine phosphatase domain-containing protein 1-like [Source:NCBI gene;Acc:103032733])

HSP 1 Score: 68.5514 bits (166), Expect = 1.009e-12
Identity = 32/98 (32.65%), Postives = 59/98 (60.20%), Query Frame = 2 
Query:  290 PPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            P V+ E  IY++   + D    +I  M    KV+ + +  +  V VHC  G GRTG+++AC+ I   ++ A E+I+++R  RP S++T +Q+ ++++F
Sbjct:  119 PQVFMENQIYFYNFGMTDFGVSSIVGMLDAVKVLTFSV-EEGKVAVHCHAGLGRTGVLIACYLIYMLRITASEAIHYVRIKRPRSIQTRAQISLVFDF 215
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Sea Lamprey
Match: dusp23b (dual specificity phosphatase 23b [Source:ZFIN;Acc:ZDB-GENE-040718-163])

HSP 1 Score: 79.337 bits (194), Expect = 1.169e-18
Identity = 49/149 (32.89%), Postives = 70/149 (46.98%), Query Frame = 2 
Query:  149 PPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYSP---FSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFY 586
            PPNFSWV PG LA  A P    H  +L + GV  +++L       +D C       P I  H   I D       ++     ++    ++   V VHC  G GRTG +LACF + H  +   +++  IR +RP S+ET  Q   +  FY
Sbjct:    6 PPNFSWVEPGRLAGLAMPHDASHYRYLYECGVRHLVSLTHGAPRHADTC-------PGIRLHAIKIEDFHPPLPEQIERFLDIVSDAGAKGEAVAVHCMHGHGRTGTMLACFLVRHRALSGVDAVAEIRRLRPGSIETREQEIAVTRFY 147
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Sea Lamprey
Match: cdc14ab (cell division cycle 14Ab [Source:NCBI gene;Acc:565969])

HSP 1 Score: 48.1358 bits (113), Expect = 5.550e-7
Identity = 19/43 (44.19%), Postives = 29/43 (67.44%), Query Frame = 2 
Query:  419 VLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESV 547
            V VHC  G GRTG ++AC+ + H ++ A E++ +IR  RP S+
Sbjct:  102 VAVHCKAGLGRTGTLIACYLMKHHRLTAAEAVAWIRICRPGSI 144
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Nematostella
Match: EDO40641 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6M3])

HSP 1 Score: 50.447 bits (119), Expect = 1.045e-7
Identity = 36/134 (26.87%), Postives = 64/134 (47.76%), Query Frame = 2 
Query:  227 LMKEGVGAIITLYSPFSDKCLPPVYEEPDIYWHI-----ATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIKQYYKS 613
            L+ E V  +ITL   F  K L    +E    W +     AT+   +  + A++    K I+   S+   V VHC  GRGR+  ++AC+ + +  +  +E+  FI++ RP+    + Q   +  F+ ++ Q   S
Sbjct:   44 LIDENVKGVITLNEEFETKHLCNSKQEW-FAWGVTQLRLATVDFGNAPSFAQLLEGVKFIEDMRSKGDSVYVHCKAGRGRSTTLVACYLMKNKNLNPEEAHLFIKSKRPQIRLASQQWIALQQFHDHLHQKKNS 176
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Nematostella
Match: EDO38271 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDJ9])

HSP 1 Score: 50.8322 bits (120), Expect = 2.306e-7
Identity = 35/157 (22.29%), Postives = 65/157 (41.40%), Query Frame = 2 
Query:  134 YIPIPPPNFSWVIPGILAASARP-------------VLREHLCFLMKEGVGAIITLYSPFSD--KCLPPVYEEPDIYWHIATICD----RSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESV 547
            Y  +   +F+W++PG   A + P                 ++ +  K  +  ++ L     D  +      E  D+++   ++      R + TIAE            +    + +HC  G GRTG ++AC+ + H +  A ESI ++R  RP S+
Sbjct:  156 YERVENGDFNWIVPGKFLAFSGPHNKSRIKDGYPLHAPEAYIPYFKKHNISTVVRLNKKLYDAQRFTDHGIEHYDLFFIDGSVPSDMIVRRFLTIAE------------NAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRPGSI 300
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Nematostella
Match: EDO38043 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE41])

HSP 1 Score: 48.1358 bits (113), Expect = 1.717e-6
Identity = 37/153 (24.18%), Postives = 67/153 (43.79%), Query Frame = 2 
Query:  161 SWVIPGILAASARPV------------LREHLCFLMKEGVGAIITLYSP---------FSDKCLPP-VYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVET 553
            +W++PG + A + P             LR+H     + GV  ++ L            +  +C     +   D Y+    I  ++   I + F   +++D+    +  V +HC  G GRTG ++AC+ I   K  A E++ ++R  RP SV +
Sbjct:  185 NWIVPGKILAMSDPQRRNEVKASRFAKLRKHF---RQNGVKTVVRLNRDDNMIKYGLVYDARCFTANGFAHSDQYFEDGGIPTKA---IVKRF--TRILDHC---EGAVAIHCRAGLGRTGTLIACYLIKQYKFSAAEAVGWLRICRPGSVSS 326
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Medaka
Match: dusp23a (dual specificity phosphatase 23 [Source:NCBI gene;Acc:101157498])

HSP 1 Score: 82.4185 bits (202), Expect = 4.879e-19
Identity = 51/152 (33.55%), Postives = 77/152 (50.66%), Query Frame = 2 
Query:  146 PPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYSPFSDKCLPPVYEE-PDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIK 598
            PP NFSWV  G LA  A P +     +L   G+  ++ L         PP +E  P++  H   I D +  + A++     +++   ++   V VHC  G GRTG +LAC+ +   K+   ++IN IR +R  S+ETT Q K +  FY  IK
Sbjct:    5 PPQNFSWVEAGRLAGLAMPRMPCDYRYLSDNGIKHLVCLCER-----KPPNHEAFPELQLHHIKIVDFTPPSPAQIDRFLSIVEEANAKKEGVAVHCMHGFGRTGTMLACYLVKSRKISGIDAINEIRRMRAGSIETTEQEKAVVQFYQRIK 151
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Medaka
Match: ptpdc1b (protein tyrosine phosphatase domain-containing protein 1-like [Source:NCBI gene;Acc:101171912])

HSP 1 Score: 72.0182 bits (175), Expect = 9.309e-14
Identity = 33/98 (33.67%), Postives = 59/98 (60.20%), Query Frame = 2 
Query:  290 PPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            P V+ E +I+++    CD     +  M  + KV+ + + ++  V VHC  G GRTG+++ACF    T+M A ++I+++R  RP S++T SQ++ +  F
Sbjct:  213 PEVFMENNIFFYNYGWCDYGVANLTTMLDMVKVMAFAL-QEGKVAVHCHAGLGRTGVLIACFLAYATRMTANQAISYVRAKRPNSIQTRSQLRCVREF 309
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Medaka
Match: ptpdc1b (protein tyrosine phosphatase domain-containing protein 1-like [Source:NCBI gene;Acc:101171912])

HSP 1 Score: 71.633 bits (174), Expect = 1.093e-13
Identity = 33/98 (33.67%), Postives = 59/98 (60.20%), Query Frame = 2 
Query:  290 PPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            P V+ E +I+++    CD     +  M  + KV+ + + ++  V VHC  G GRTG+++ACF    T+M A ++I+++R  RP S++T SQ++ +  F
Sbjct:  136 PEVFMENNIFFYNYGWCDYGVANLTTMLDMVKVMAFAL-QEGKVAVHCHAGLGRTGVLIACFLAYATRMTANQAISYVRAKRPNSIQTRSQLRCVREF 232
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Medaka
Match: zgc:77752 (zgc:77752 [Source:ZFIN;Acc:ZDB-GENE-040426-1867])

HSP 1 Score: 63.929 bits (154), Expect = 3.276e-11
Identity = 27/98 (27.55%), Postives = 59/98 (60.20%), Query Frame = 2 
Query:  290 PPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            P  + + DIY++   + D    ++  +    KV+D+ + ++  V +HC  G GRTG+++AC+ I   ++   E+++++R  RP S++T +Q+  +++F
Sbjct:  122 PQTFMDNDIYFYNFGMPDYGVSSLVGIIDGLKVLDFAV-KEGRVAIHCHAGLGRTGVLIACYLIYTLRISPSEAVHYVRIKRPRSIQTRTQINQVFDF 218
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Medaka
Match: ptpdc1a (protein tyrosine phosphatase domain containing 1 [Source:NCBI gene;Acc:101157363])

HSP 1 Score: 60.077 bits (144), Expect = 7.206e-10
Identity = 27/98 (27.55%), Postives = 54/98 (55.10%), Query Frame = 2 
Query:  290 PPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNF 583
            P  + +  +Y++     D    ++  +  + KV+ + + ++  + VHC  G GRTG++LAC+ +   +M A ++I F+R  RP S++T  Q+  +  F
Sbjct:  120 PETFMQAGVYYYNFGWKDYGVASLTTILDMVKVMSFAV-QEGKMAVHCHAGLGRTGVLLACYLVFTARMNADQAILFVRAKRPNSIQTRGQLLCVREF 216
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Planmine SMEST
Match: SMESG000020520.1 (SMESG000020520.1)

HSP 1 Score: 496.508 bits (1277), Expect = 1.591e-180
Identity = 240/240 (100.00%), Postives = 240/240 (100.00%), Query Frame = 2 
Query:  110 MLNNVQPKYIPIPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYSPFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIKQYYKSFKTHILDGVFKTNSLKRKFEIPKSFSRNLFEATIFCRQNKILRTLEKQRLNTQVSISKKSKKLINAFAIDEK 829
            MLNNVQPKYIPIPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYSPFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIKQYYKSFKTHILDGVFKTNSLKRKFEIPKSFSRNLFEATIFCRQNKILRTLEKQRLNTQVSISKKSKKLINAFAIDEK
Sbjct:    1 MLNNVQPKYIPIPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYSPFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIKQYYKSFKTHILDGVFKTNSLKRKFEIPKSFSRNLFEATIFCRQNKILRTLEKQRLNTQVSISKKSKKLINAFAIDEK 240
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Planmine SMEST
Match: SMESG000020520.1 (SMESG000020520.1)

HSP 1 Score: 468.389 bits (1204), Expect = 1.946e-169
Identity = 230/240 (95.83%), Postives = 230/240 (95.83%), Query Frame = 2 
Query:  110 MLNNVQPKYIPIPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYSPFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIKQYYKSFKTHILDGVFKTNSLKRKFEIPKSFSRNLFEATIFCRQNKILRTLEKQRLNTQVSISKKSKKLINAFAIDEK 829
            MLNNVQPKYIPIPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYSPFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQK          PVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIKQYYKSFKTHILDGVFKTNSLKRKFEIPKSFSRNLFEATIFCRQNKILRTLEKQRLNTQVSISKKSKKLINAFAIDEK
Sbjct:    1 MLNNVQPKYIPIPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIITLYSPFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQK----------PVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTSQMKMIYNFYLNIKQYYKSFKTHILDGVFKTNSLKRKFEIPKSFSRNLFEATIFCRQNKILRTLEKQRLNTQVSISKKSKKLINAFAIDEK 230
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Planmine SMEST
Match: SMESG000057887.1 (SMESG000057887.1)

HSP 1 Score: 51.2174 bits (121), Expect = 4.775e-7
Identity = 38/151 (25.17%), Postives = 61/151 (40.40%), Query Frame = 2 
Query:  134 YIPIPPPNFSWVIPGILAASARPVLRE-------------HLCFLMKEGVGAIITLYSPFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESV 547
            Y  +   +F+W++PG   A   P  +              +  +  K  V  II L     D      + E     H     D S  T +   ++++ ++   +    + VHC  G GRTG ++ C+ + H K  A E I +IR  RP SV
Sbjct:  182 YEKVENGDFNWIVPGKFLAFCGPFHQSKIENGFPLHAPEAYFPYFRKNNVQTIIRLNKKIYDSRR---FTEAGFKHHELFFVDGSVPTDS---IVRQFLEICETSSGAIAVHCKAGLGRTGTLIGCYLMKHYKFTAAEVIGWIRICRPGSV 326
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Planmine SMEST
Match: SMESG000057887.1 (SMESG000057887.1)

HSP 1 Score: 51.2174 bits (121), Expect = 5.039e-7
Identity = 38/151 (25.17%), Postives = 61/151 (40.40%), Query Frame = 2 
Query:  134 YIPIPPPNFSWVIPGILAASARPVLRE-------------HLCFLMKEGVGAIITLYSPFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESV 547
            Y  +   +F+W++PG   A   P  +              +  +  K  V  II L     D      + E     H     D S  T +   ++++ ++   +    + VHC  G GRTG ++ C+ + H K  A E I +IR  RP SV
Sbjct:  182 YEKVENGDFNWIVPGKFLAFCGPFHQSKIENGFPLHAPEAYFPYFRKNNVQTIIRLNKKIYDSRR---FTEAGFKHHELFFVDGSVPTDS---IVRQFLEICETSSGAIAVHCKAGLGRTGTLIGCYLMKHYKFTAAEVIGWIRICRPGSV 326
[Close]
BLAST of Dual specificity protein phosphatase 23 vs. Planmine SMEST
Match: SMESG000057887.1 (SMESG000057887.1)

HSP 1 Score: 51.2174 bits (121), Expect = 5.067e-7
Identity = 38/151 (25.17%), Postives = 61/151 (40.40%), Query Frame = 2 
Query:  134 YIPIPPPNFSWVIPGILAASARPVLRE-------------HLCFLMKEGVGAIITLYSPFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISRDVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESV 547
            Y  +   +F+W++PG   A   P  +              +  +  K  V  II L     D      + E     H     D S  T +   ++++ ++   +    + VHC  G GRTG ++ C+ + H K  A E I +IR  RP SV
Sbjct:  173 YEKVENGDFNWIVPGKFLAFCGPFHQSKIENGFPLHAPEAYFPYFRKNNVQTIIRLNKKIYDSRR---FTEAGFKHHELFFVDGSVPTDS---IVRQFLEICETSSGAIAVHCKAGLGRTGTLIGCYLMKHYKFTAAEVIGWIRICRPGSV 317
The following BLAST results are available for this feature:
BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DUSP237.615e-2536.13dual specificity phosphatase 23 [Source:HGNC Symbo... [more]
DUSP237.615e-2536.13dual specificity phosphatase 23 [Source:HGNC Symbo... [more]
DUSP237.615e-2536.13dual specificity phosphatase 23 [Source:HGNC Symbo... [more]
PTPDC11.605e-1128.30protein tyrosine phosphatase domain containing 1 [... [more]
PTPDC11.619e-1128.30protein tyrosine phosphatase domain containing 1 [... [more]
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BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
T12B3.16.848e-832.43pep chromosome:WBcel235:IV:7382415:7384752:1 gene:... [more]
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BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dusp23a4.393e-2432.67dual specificity phosphatase 23a [Source:ZFIN;Acc:... [more]
dusp23a4.393e-2432.67dual specificity phosphatase 23a [Source:ZFIN;Acc:... [more]
dusp23b1.504e-2235.57dual specificity phosphatase 23b [Source:ZFIN;Acc:... [more]
BX571879.22.903e-1228.31pep chromosome:GRCz11:CHR_ALT_CTG18_1_3:7591744:76... [more]
zgc:777523.068e-1228.31zgc:77752 [Source:ZFIN;Acc:ZDB-GENE-040426-1867][more]
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BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mettl141.611e-2537.82methyltransferase like 14 [Source:Xenbase;Acc:XB-G... [more]
PTPDC11.682e-829.29protein tyrosine phosphatase domain containing 1 [... [more]
PTPDC12.072e-829.29protein tyrosine phosphatase domain containing 1 [... [more]
CDC14A1.259e-620.89cell division cycle 14A [Source:NCBI gene;Acc:1004... [more]
CDC14A2.144e-620.92cell division cycle 14A [Source:NCBI gene;Acc:1004... [more]
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BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dusp231.096e-2636.77dual specificity phosphatase 23 [Source:MGI Symbol... [more]
Ptpdc15.347e-1228.93protein tyrosine phosphatase domain containing 1 [... [more]
Ptpdc16.400e-1228.93protein tyrosine phosphatase domain containing 1 [... [more]
Ptpdc16.485e-1228.93protein tyrosine phosphatase domain containing 1 [... [more]
Cdc14b1.862e-729.82CDC14 cell division cycle 14B [Source:MGI Symbol;A... [more]
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BLAST of Dual specificity protein phosphatase 23 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6NT99|DUS23_MOUSE7.665e-2636.77Dual specificity protein phosphatase 23 OS=Mus mus... [more]
sp|Q9BVJ7|DUS23_HUMAN3.657e-2436.13Dual specificity protein phosphatase 23 OS=Homo sa... [more]
sp|A7E379|PTPC1_BOVIN6.014e-1228.93Protein tyrosine phosphatase domain-containing pro... [more]
sp|Q6NZK8|PTPC1_MOUSE4.536e-1128.93Protein tyrosine phosphatase domain-containing pro... [more]
sp|A2A3K4|PTPC1_HUMAN7.835e-1128.30Protein tyrosine phosphatase domain-containing pro... [more]
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BLAST of Dual specificity protein phosphatase 23 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2Y9FV545.947e-2336.77dual specificity protein phosphatase 23 OS=Physete... [more]
D3ZRL36.541e-2337.42Dual-specificity phosphatase 23 OS=Rattus norvegic... [more]
A0A2Y9M0R47.504e-2336.77dual specificity protein phosphatase 23 OS=Delphin... [more]
A0A383ZAE57.504e-2336.77dual specificity protein phosphatase 23 OS=Balaeno... [more]
A0A341BX307.504e-2336.77dual specificity protein phosphatase 23 isoform X1... [more]
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BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dusp23b1.421e-2133.99dual specificity protein phosphatase 23-like [Sour... [more]
dusp23b1.132e-2033.99dual specificity protein phosphatase 23-like [Sour... [more]
ENSAMXT00000043439.11.606e-1833.12dual specificity protein phosphatase 23-like [Sour... [more]
zgc:777529.776e-1332.65protein tyrosine phosphatase domain-containing pro... [more]
zgc:777521.009e-1232.65protein tyrosine phosphatase domain-containing pro... [more]
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BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
dusp23b1.169e-1832.89dual specificity phosphatase 23b [Source:ZFIN;Acc:... [more]
cdc14ab5.550e-744.19cell division cycle 14Ab [Source:NCBI gene;Acc:565... [more]
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BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO406411.045e-726.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO382712.306e-722.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO380431.717e-624.18Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Dual specificity protein phosphatase 23 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dusp23a4.879e-1933.55dual specificity phosphatase 23 [Source:NCBI gene;... [more]
ptpdc1b9.309e-1433.67protein tyrosine phosphatase domain-containing pro... [more]
ptpdc1b1.093e-1333.67protein tyrosine phosphatase domain-containing pro... [more]
zgc:777523.276e-1127.55zgc:77752 [Source:ZFIN;Acc:ZDB-GENE-040426-1867][more]
ptpdc1a7.206e-1027.55protein tyrosine phosphatase domain containing 1 [... [more]
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BLAST of Dual specificity protein phosphatase 23 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000020520.11.591e-180100.00SMESG000020520.1[more]
SMESG000020520.11.946e-16995.83SMESG000020520.1[more]
SMESG000057887.14.775e-725.17SMESG000057887.1[more]
SMESG000057887.15.039e-725.17SMESG000057887.1[more]
SMESG000057887.15.067e-725.17SMESG000057887.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006824 ID=SMED30006824|Name=Dual specificity protein phosphatase 23|organism=Schmidtea mediterranea sexual|type=transcript|length=843bp
TTAAGTCATGTAATTTATTTAGTTTTTCAACATCTTCTAATTAACCATAT
ATATTATTATTTAATTATTTATAATTAAGGATTATTGTAAATCATTTAAT
GAAAAATTTATGCTGAACAACGTACAGCCAAAATATATTCCAATCCCACC
ACCTAATTTTAGTTGGGTAATTCCCGGAATATTGGCTGCAAGTGCCAGGC
CAGTTCTGAGAGAACATTTGTGCTTCTTAATGAAAGAAGGAGTCGGAGCA
ATTATTACACTCTATTCACCATTTTCCGACAAATGTTTACCTCCAGTATA
TGAAGAGCCAGATATTTATTGGCACATTGCTACTATTTGTGATCGTAGCT
ATTTTACAATTGCAGAAATGTTTCTCATTCAAAAAGTAATAGATTATTAT
ATTTCAAGAGATGTTCCTGTATTGGTCCACTGCTCTTGGGGCCGTGGTCG
AACTGGAATAGTTCTTGCATGCTTCTTTATCATTCACACAAAAATGAAAG
CTAAGGAAAGCATAAATTTCATTAGAACAATACGACCGGAATCAGTGGAG
ACGACTTCTCAAATGAAAATGATTTACAATTTCTACCTAAATATAAAGCA
GTACTATAAATCATTCAAAACGCATATATTAGATGGAGTATTTAAAACAA
ATTCCTTAAAAAGAAAATTTGAAATTCCGAAATCGTTTTCTCGAAATTTA
TTTGAAGCAACAATATTCTGTAGACAAAACAAAATACTGCGCACGTTAGA
GAAACAACGCTTAAATACTCAAGTTTCAATTTCAAAAAAAAGCAAAAAAC
TTATAAATGCTTTCGCAATAGACGAAAAATGAAATAATTGCAC
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protein sequence of SMED30006824-orf-1

>SMED30006824-orf-1 ID=SMED30006824-orf-1|Name=SMED30006824-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=241bp
MLNNVQPKYIPIPPPNFSWVIPGILAASARPVLREHLCFLMKEGVGAIIT
LYSPFSDKCLPPVYEEPDIYWHIATICDRSYFTIAEMFLIQKVIDYYISR
DVPVLVHCSWGRGRTGIVLACFFIIHTKMKAKESINFIRTIRPESVETTS
QMKMIYNFYLNIKQYYKSFKTHILDGVFKTNSLKRKFEIPKSFSRNLFEA
TIFCRQNKILRTLEKQRLNTQVSISKKSKKLINAFAIDEK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR003595Tyr_Pase_cat
IPR000340Dual-sp_phosphatase_cat-dom
IPR029021Prot-tyrosine_phosphatase-like
IPR016130Tyr_Pase_AS
IPR000387TYR_PHOSPHATASE_dom
Vocabulary: biological process
TermDefinition
GO:0006470protein dephosphorylation
GO:0016311dephosphorylation
GO:0035335peptidyl-tyrosine dephosphorylation
Vocabulary: molecular function
TermDefinition
GO:0008138protein tyrosine/serine/threonine phosphatase activity
GO:0016791phosphatase activity
GO:0004725protein tyrosine phosphatase activity
GO:0004721phosphoprotein phosphatase activity
GO:0004722protein serine/threonine phosphatase activity
GO:0016787hydrolase activity
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005737cytoplasm
GO:0005829cytosol
GO:0070062extracellular exosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003595Protein-tyrosine phosphatase, catalyticSMARTSM00404ptp_7coord: 67..161
e-value: 0.001
score: 22.4
IPR000340Dual specificity phosphatase, catalytic domainPFAMPF00782DSPccoord: 86..159
e-value: 3.8E-11
score: 42.9
IPR029021Protein-tyrosine phosphatase-likeGENE3DG3DSA:3.90.190.10coord: 11..162
e-value: 1.3E-26
score: 95.4
IPR029021Protein-tyrosine phosphatase-likeSUPERFAMILYSSF52799(Phosphotyrosine protein) phosphatases IIcoord: 7..164
NoneNo IPR availablePANTHERPTHR23339:SF26DUAL SPECIFICITY PROTEIN PHOSPHATASE 23coord: 9..165
NoneNo IPR availablePANTHERPTHR23339TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASEcoord: 9..165
NoneNo IPR availableCDDcd14504DUSP23coord: 17..159
e-value: 6.0907E-39
score: 130.09
IPR016130Protein-tyrosine phosphatase, active sitePROSITEPS00383TYR_PHOSPHATASE_1coord: 106..116
IPR000387Tyrosine specific protein phosphatases domainPROSITEPS50056TYR_PHOSPHATASE_2coord: 79..153
score: 14.997