SMED30006822

Overview
NameSMED30006822
Smed IDSMED30006822
Length (bp)2997
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30006822 (SMED30006822) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30006822 (SMED30006822) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30006822 (SMED30006822) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30006822 (SMED30006822) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006822

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30006822SMESG000043386.1 dd_Smed_v4_15542_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30006822SMESG000043386.1 dd_Smed_v4_15542_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30006822SMESG000043386.1 dd_Smed_v4_15542_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30006822SMESG000043386.1 dd_Smed_v6_15542_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30006822SMESG000043386.1 dd_Smed_v4_15542_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30006822 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.001235:90117..93169 +14565
Homology
[Close]
BLAST of SMED30006822 vs. Ensembl Human
Match: MOK (MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:9833])

HSP 1 Score: 61.6178 bits (148), Expect = 3.840e-19
Identity = 27/46 (58.70%), Postives = 33/46 (71.74%), Query Frame = -1 
Query:  745 SKLSFKIKIYHKRYRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 882
            SK  +   I  + YRAPECLLTDG+Y+Y+MDLWS GCV +EI   Q
Sbjct:   34 SKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQ 79

HSP 2 Score: 55.0694 bits (131), Expect = 3.840e-19
Identity = 23/37 (62.16%), Postives = 29/37 (78.38%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL+PLFPG NE+DQI KIHD++G+P   IL  FK+
Sbjct:   75 IASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQ 111

HSP 3 Score: 50.447 bits (119), Expect = 8.084e-11
Identity = 18/26 (69.23%), Postives = 24/26 (92.31%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ DFGSC++++S+ PYTEYISTRW
Sbjct:   21 LKLGDFGSCRSVYSKQPYTEYISTRW 46

HSP 4 Score: 37.7354 bits (86), Expect = 8.084e-11
Identity = 15/16 (93.75%), Postives = 16/16 (100.00%), Query Frame = -1 
Query: 2020 NGIFHRDVKPENILIR 2067
            NGIFHRDVKPENILI+
Sbjct:    2 NGIFHRDVKPENILIK 17
[Close]
BLAST of SMED30006822 vs. Ensembl Human
Match: MOK (MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:9833])

HSP 1 Score: 61.6178 bits (148), Expect = 5.722e-19
Identity = 24/33 (72.73%), Postives = 28/33 (84.85%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPECLLTDG+Y+Y+MDLWS GCV +EI   Q
Sbjct:  166 YRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQ 198

HSP 2 Score: 53.9138 bits (128), Expect = 5.722e-19
Identity = 23/37 (62.16%), Postives = 29/37 (78.38%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL+PLFPG NE+DQI KIHD++G+P   IL  FK+
Sbjct:  194 IASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQ 230

HSP 3 Score: 51.9878 bits (123), Expect = 3.059e-12
Identity = 18/26 (69.23%), Postives = 24/26 (92.31%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ DFGSC++++S+ PYTEYISTRW
Sbjct:  140 LKLGDFGSCRSVYSKQPYTEYISTRW 165

HSP 4 Score: 40.817 bits (94), Expect = 3.059e-12
Identity = 16/20 (80.00%), Postives = 19/20 (95.00%), Query Frame = -1 
Query: 2011 RNGIFHRDVKPENILIRVII 2070
            RNGIFHRDVKPENILI+ ++
Sbjct:  121 RNGIFHRDVKPENILIKDVL 140
[Close]
BLAST of SMED30006822 vs. Ensembl Human
Match: MOK (MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:9833])

HSP 1 Score: 61.6178 bits (148), Expect = 5.817e-19
Identity = 24/33 (72.73%), Postives = 28/33 (84.85%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPECLLTDG+Y+Y+MDLWS GCV +EI   Q
Sbjct:  167 YRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQ 199

HSP 2 Score: 53.9138 bits (128), Expect = 5.817e-19
Identity = 23/37 (62.16%), Postives = 29/37 (78.38%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL+PLFPG NE+DQI KIHD++G+P   IL  FK+
Sbjct:  195 IASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQ 231

HSP 3 Score: 51.9878 bits (123), Expect = 5.154e-12
Identity = 18/26 (69.23%), Postives = 24/26 (92.31%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ DFGSC++++S+ PYTEYISTRW
Sbjct:  141 LKLGDFGSCRSVYSKQPYTEYISTRW 166

HSP 4 Score: 40.0466 bits (92), Expect = 5.154e-12
Identity = 18/32 (56.25%), Postives = 23/32 (71.88%), Query Frame = -1 
Query: 1975 RNGIFHRDVKPENILIRVIIFFNYSRFGNYFS 2070
            RNGIFHRDVKPENILI+  +     + G++ S
Sbjct:  121 RNGIFHRDVKPENILIKQDVL----KLGDFGS 148
[Close]
BLAST of SMED30006822 vs. Ensembl Human
Match: MOK (MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:9833])

HSP 1 Score: 61.6178 bits (148), Expect = 6.536e-19
Identity = 24/33 (72.73%), Postives = 28/33 (84.85%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPECLLTDG+Y+Y+MDLWS GCV +EI   Q
Sbjct:  137 YRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQ 169

HSP 2 Score: 53.9138 bits (128), Expect = 6.536e-19
Identity = 23/37 (62.16%), Postives = 29/37 (78.38%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL+PLFPG NE+DQI KIHD++G+P   IL  FK+
Sbjct:  165 IASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQ 201

HSP 3 Score: 51.9878 bits (123), Expect = 4.801e-12
Identity = 18/26 (69.23%), Postives = 24/26 (92.31%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ DFGSC++++S+ PYTEYISTRW
Sbjct:  111 LKLGDFGSCRSVYSKQPYTEYISTRW 136

HSP 4 Score: 40.4318 bits (93), Expect = 4.801e-12
Identity = 18/32 (56.25%), Postives = 23/32 (71.88%), Query Frame = -1 
Query: 1975 RNGIFHRDVKPENILIRVIIFFNYSRFGNYFS 2070
            RNGIFHRDVKPENILI+  +     + G++ S
Sbjct:   91 RNGIFHRDVKPENILIKQDVL----KLGDFGS 118
[Close]
BLAST of SMED30006822 vs. Ensembl Human
Match: ICK (intestinal cell kinase [Source:HGNC Symbol;Acc:HGNC:21219])

HSP 1 Score: 42.743 bits (99), Expect = 3.842e-9
Identity = 18/43 (41.86%), Postives = 27/43 (62.79%), Query Frame = -1 
Query:  757 KSKLSFKIKIYHKRYRAPECLLTDGYYSYQMDLWSVGCVMFEI 885
            +SK  +   +  + YRAPE LL    YS  +D+W+VGC+M E+
Sbjct:  151 RSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEV 193

HSP 2 Score: 39.6614 bits (91), Expect = 3.842e-9
Identity = 16/30 (53.33%), Postives = 24/30 (80.00%), Query Frame = -3 
Query:  626 IFSLRPLFPGANEVDQIGKIHDILGSPDAS 715
            +++LRPLFPGA+E+D I KI  +LG+P  +
Sbjct:  193 VYTLRPLFPGASEIDTIFKICQVLGTPKKT 222

HSP 3 Score: 41.5874 bits (96), Expect = 8.534e-6
Identity = 19/46 (41.30%), Postives = 30/46 (65.22%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  + I S+ PYT+Y+STRW      L +  ++Y +P+ +
Sbjct:  139 VKIADFGLAREIRSKPPYTDYVSTRWYRAPEVL-LRSTNYSSPIDV 183

HSP 4 Score: 29.6462 bits (65), Expect = 8.534e-6
Identity = 10/15 (66.67%), Postives = 14/15 (93.33%), Query Frame = -1 
Query: 2026 RNGIFHRDVKPENIL 2070
            ++G FHRD+KPEN+L
Sbjct:  118 KHGFFHRDLKPENLL 132
[Close]
BLAST of SMED30006822 vs. Ensembl Celegans
Match: dyf-5 (Serine/threonine-protein kinase dyf-5 [Source:UniProtKB/Swiss-Prot;Acc:B3WFY8])

HSP 1 Score: 39.2762 bits (90), Expect = 1.915e-8
Identity = 14/29 (48.28%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    Y+  +D+W++GC+M E+
Sbjct:  172 YRAPEILLRSTSYNSPIDMWALGCIMAEL 200

HSP 2 Score: 39.2762 bits (90), Expect = 1.915e-8
Identity = 16/28 (57.14%), Postives = 23/28 (82.14%), Query Frame = -3 
Query:  632 IFSLRPLFPGANEVDQIGKIHDILGSPD 715
            ++ LRPLFPG +E+DQ+ KI  ILG+P+
Sbjct:  200 LYILRPLFPGTSEMDQLFKIISILGTPN 227

HSP 3 Score: 41.2022 bits (95), Expect = 3.684e-7
Identity = 20/46 (43.48%), Postives = 29/46 (63.04%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  + I S+ PYT+Y+STRW      L  + S Y +P+ +
Sbjct:  146 VKIADFGLAREIRSKPPYTDYVSTRWYRAPEILLRSTS-YNSPIDM 190

HSP 4 Score: 33.113 bits (74), Expect = 3.684e-7
Identity = 13/28 (46.43%), Postives = 17/28 (60.71%), Query Frame = -1 
Query: 1987 RNGIFHRDVKPENILIRVIIFFNYSRFG 2070
            +NG FHRD+KPENI+         + FG
Sbjct:  125 KNGFFHRDMKPENIMCNGTELVKIADFG 152
[Close]
BLAST of SMED30006822 vs. Ensembl Celegans
Match: dyf-5 (Serine/threonine-protein kinase dyf-5 [Source:UniProtKB/Swiss-Prot;Acc:B3WFY8])

HSP 1 Score: 39.2762 bits (90), Expect = 2.094e-8
Identity = 16/43 (37.21%), Postives = 27/43 (62.79%), Query Frame = -1 
Query:  757 KSKLSFKIKIYHKRYRAPECLLTDGYYSYQMDLWSVGCVMFEI 885
            +SK  +   +  + YRAPE LL    Y+  +D+W++GC+M E+
Sbjct:  158 RSKPPYTDYVSTRWYRAPEILLRSTSYNSPIDMWALGCIMAEL 200

HSP 2 Score: 39.2762 bits (90), Expect = 2.094e-8
Identity = 16/28 (57.14%), Postives = 23/28 (82.14%), Query Frame = -3 
Query:  632 IFSLRPLFPGANEVDQIGKIHDILGSPD 715
            ++ LRPLFPG +E+DQ+ KI  ILG+P+
Sbjct:  200 LYILRPLFPGTSEMDQLFKIISILGTPN 227

HSP 3 Score: 41.2022 bits (95), Expect = 3.601e-7
Identity = 20/46 (43.48%), Postives = 29/46 (63.04%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  + I S+ PYT+Y+STRW      L  + S Y +P+ +
Sbjct:  146 VKIADFGLAREIRSKPPYTDYVSTRWYRAPEILLRSTS-YNSPIDM 190

HSP 4 Score: 33.113 bits (74), Expect = 3.601e-7
Identity = 13/28 (46.43%), Postives = 17/28 (60.71%), Query Frame = -1 
Query: 1987 RNGIFHRDVKPENILIRVIIFFNYSRFG 2070
            +NG FHRD+KPENI+         + FG
Sbjct:  125 KNGFFHRDMKPENIMCNGTELVKIADFG 152
[Close]
BLAST of SMED30006822 vs. Ensembl Celegans
Match: cdk-11.1 (Cyclin-dependent kinase 11.1 [Source:UniProtKB/Swiss-Prot;Acc:Q09437])

HSP 1 Score: 40.817 bits (94), Expect = 2.587e-7
Identity = 16/30 (53.33%), Postives = 21/30 (70.00%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YR+PE LL    YS  +D+WSVGC+M E +
Sbjct:  525 YRSPELLLGTRLYSTPVDMWSVGCIMAEFI 554

HSP 2 Score: 33.8834 bits (76), Expect = 2.587e-7
Identity = 15/29 (51.72%), Postives = 20/29 (68.97%), Query Frame = -3 
Query:  620 LRPLFPGANEVDQIGKIHDILGSPDASIL 706
            L+PLFPG  E++QI KI   +G+P  SI 
Sbjct:  556 LKPLFPGRGELEQIKKIFMEMGTPTESIW 584
[Close]
BLAST of SMED30006822 vs. Ensembl Celegans
Match: cdk-11.1 (Cyclin-dependent kinase 11.1 [Source:UniProtKB/Swiss-Prot;Acc:Q09437])

HSP 1 Score: 40.817 bits (94), Expect = 2.652e-7
Identity = 16/30 (53.33%), Postives = 21/30 (70.00%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YR+PE LL    YS  +D+WSVGC+M E +
Sbjct:  515 YRSPELLLGTRLYSTPVDMWSVGCIMAEFI 544

HSP 2 Score: 33.8834 bits (76), Expect = 2.652e-7
Identity = 15/29 (51.72%), Postives = 20/29 (68.97%), Query Frame = -3 
Query:  620 LRPLFPGANEVDQIGKIHDILGSPDASIL 706
            L+PLFPG  E++QI KI   +G+P  SI 
Sbjct:  546 LKPLFPGRGELEQIKKIFMEMGTPTESIW 574
[Close]
BLAST of SMED30006822 vs. Ensembl Celegans
Match: pmk-1 (Mitogen-activated protein kinase pmk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q17446])

HSP 1 Score: 38.5058 bits (88), Expect = 7.711e-7
Identity = 14/30 (46.67%), Postives = 23/30 (76.67%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPE +L   +Y+  +D+WSVGC++ E++
Sbjct:  199 YRAPEIMLNWMHYTQTVDVWSVGCILAELI 228

HSP 2 Score: 34.6538 bits (78), Expect = 7.711e-7
Identity = 12/29 (41.38%), Postives = 20/29 (68.97%), Query Frame = -3 
Query:  617 RPLFPGANEVDQIGKIHDILGSPDASILK 703
            + LFPG++ +DQ+ +I  + G+PD   LK
Sbjct:  231 KTLFPGSDHIDQLTRIMSVTGTPDEEFLK 259
[Close]
BLAST of SMED30006822 vs. Ensembl Fly
Match: CG42366 (gene:FBgn0259712 transcript:FBtr0331633)

HSP 1 Score: 42.3578 bits (98), Expect = 5.780e-10
Identity = 18/47 (38.30%), Postives = 28/47 (59.57%), Query Frame = -1 
Query:  745 KSKLSFKIKIYHKRYRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 885
            +S+  F   +  + YRAPE LL    Y   +DLW++GC+M E+  F+
Sbjct:  151 RSRPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYTFR 197

HSP 2 Score: 42.3578 bits (98), Expect = 5.780e-10
Identity = 16/28 (57.14%), Postives = 24/28 (85.71%), Query Frame = -3 
Query:  632 IFSLRPLFPGANEVDQIGKIHDILGSPD 715
            +++ RPLFPG++EVDQ+ KI  +LG+PD
Sbjct:  193 LYTFRPLFPGSSEVDQLFKICSVLGTPD 220

HSP 3 Score: 40.4318 bits (93), Expect = 2.070e-6
Identity = 16/26 (61.54%), Postives = 21/26 (80.77%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            +KIADFG  + I SR P+T+Y+STRW
Sbjct:  139 IKIADFGLAREIRSRPPFTDYVSTRW 164

HSP 4 Score: 31.9574 bits (71), Expect = 2.070e-6
Identity = 13/28 (46.43%), Postives = 17/28 (60.71%), Query Frame = -1 
Query: 1987 RNGIFHRDVKPENILIRVIIFFNYSRFG 2070
            R+G FHRD+KPEN+L         + FG
Sbjct:  118 RHGFFHRDLKPENLLCSGPDLIKIADFG 145
[Close]
BLAST of SMED30006822 vs. Ensembl Fly
Match: CG42366 (gene:FBgn0259712 transcript:FBtr0299965)

HSP 1 Score: 42.3578 bits (98), Expect = 5.928e-10
Identity = 18/47 (38.30%), Postives = 28/47 (59.57%), Query Frame = -1 
Query:  745 KSKLSFKIKIYHKRYRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 885
            +S+  F   +  + YRAPE LL    Y   +DLW++GC+M E+  F+
Sbjct:  151 RSRPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYTFR 197

HSP 2 Score: 42.3578 bits (98), Expect = 5.928e-10
Identity = 16/28 (57.14%), Postives = 24/28 (85.71%), Query Frame = -3 
Query:  632 IFSLRPLFPGANEVDQIGKIHDILGSPD 715
            +++ RPLFPG++EVDQ+ KI  +LG+PD
Sbjct:  193 LYTFRPLFPGSSEVDQLFKICSVLGTPD 220

HSP 3 Score: 40.4318 bits (93), Expect = 1.988e-6
Identity = 16/26 (61.54%), Postives = 21/26 (80.77%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            +KIADFG  + I SR P+T+Y+STRW
Sbjct:  139 IKIADFGLAREIRSRPPFTDYVSTRW 164

HSP 4 Score: 31.9574 bits (71), Expect = 1.988e-6
Identity = 13/28 (46.43%), Postives = 17/28 (60.71%), Query Frame = -1 
Query: 1987 RNGIFHRDVKPENILIRVIIFFNYSRFG 2070
            R+G FHRD+KPEN+L         + FG
Sbjct:  118 RHGFFHRDLKPENLLCSGPDLIKIADFG 145
[Close]
BLAST of SMED30006822 vs. Ensembl Fly
Match: Pitslre (gene:FBgn0016696 transcript:FBtr0304935)

HSP 1 Score: 41.2022 bits (95), Expect = 5.596e-7
Identity = 17/32 (53.12%), Postives = 21/32 (65.62%), Query Frame = -1 
Query:  748 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRF 843
            YRAPE LL    YS  +D+WSVGC+  E L+ 
Sbjct:  552 YRAPELLLCSPVYSTPIDVWSVGCIFAEFLQM 583

HSP 2 Score: 33.113 bits (74), Expect = 5.596e-7
Identity = 12/30 (40.00%), Postives = 20/30 (66.67%), Query Frame = -3 
Query:  611 PLFPGANEVDQIGKIHDILGSPDASILKNF 700
            PLFPG +E+D++ +I   LG+P+  I   +
Sbjct:  585 PLFPGKSEIDELNRIFKELGTPNEKIWPGY 614
[Close]
BLAST of SMED30006822 vs. Ensembl Fly
Match: Pitslre (gene:FBgn0016696 transcript:FBtr0304936)

HSP 1 Score: 41.2022 bits (95), Expect = 5.596e-7
Identity = 17/32 (53.12%), Postives = 21/32 (65.62%), Query Frame = -1 
Query:  748 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRF 843
            YRAPE LL    YS  +D+WSVGC+  E L+ 
Sbjct:  552 YRAPELLLCSPVYSTPIDVWSVGCIFAEFLQM 583

HSP 2 Score: 33.113 bits (74), Expect = 5.596e-7
Identity = 12/30 (40.00%), Postives = 20/30 (66.67%), Query Frame = -3 
Query:  611 PLFPGANEVDQIGKIHDILGSPDASILKNF 700
            PLFPG +E+D++ +I   LG+P+  I   +
Sbjct:  585 PLFPGKSEIDELNRIFKELGTPNEKIWPGY 614
[Close]
BLAST of SMED30006822 vs. Ensembl Fly
Match: Pitslre (gene:FBgn0016696 transcript:FBtr0331523)

HSP 1 Score: 41.2022 bits (95), Expect = 5.596e-7
Identity = 17/32 (53.12%), Postives = 21/32 (65.62%), Query Frame = -1 
Query:  748 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRF 843
            YRAPE LL    YS  +D+WSVGC+  E L+ 
Sbjct:  552 YRAPELLLCSPVYSTPIDVWSVGCIFAEFLQM 583

HSP 2 Score: 33.113 bits (74), Expect = 5.596e-7
Identity = 12/30 (40.00%), Postives = 20/30 (66.67%), Query Frame = -3 
Query:  611 PLFPGANEVDQIGKIHDILGSPDASILKNF 700
            PLFPG +E+D++ +I   LG+P+  I   +
Sbjct:  585 PLFPGKSEIDELNRIFKELGTPNEKIWPGY 614
[Close]
BLAST of SMED30006822 vs. Ensembl Zebrafish
Match: mak (male germ cell-associated kinase [Source:ZFIN;Acc:ZDB-GENE-030131-7279])

HSP 1 Score: 42.3578 bits (98), Expect = 2.084e-8
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D+W+VGC+M E+
Sbjct:  165 YRAPEVLLRSPVYSSPIDIWAVGCIMAEL 193

HSP 2 Score: 36.965 bits (84), Expect = 2.084e-8
Identity = 15/26 (57.69%), Postives = 22/26 (84.62%), Query Frame = -3 
Query:  638 IFSLRPLFPGANEVDQIGKIHDILGS 715
            +++LRPLFPG +EVD+I KI  +LG+
Sbjct:  193 LYTLRPLFPGNSEVDEIFKICQVLGT 218

HSP 3 Score: 41.5874 bits (96), Expect = 1.458e-6
Identity = 17/26 (65.38%), Postives = 21/26 (80.77%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            +KIADFG  + I SR PYT+Y+STRW
Sbjct:  139 VKIADFGLAREIRSRPPYTDYVSTRW 164

HSP 4 Score: 31.5722 bits (70), Expect = 1.458e-6
Identity = 14/39 (35.90%), Postives = 20/39 (51.28%), Query Frame = -1 
Query: 1987 FYCFELFSLNSRNGIFHRDVKPENILIRVIIFFNYSRFG 2103
            F   +  S   ++G FHRD+KPEN+L         + FG
Sbjct:  107 FQILQGLSFIHKHGFFHRDMKPENLLCMGPELVKIADFG 145
[Close]
BLAST of SMED30006822 vs. Ensembl Zebrafish
Match: mak (male germ cell-associated kinase [Source:ZFIN;Acc:ZDB-GENE-030131-7279])

HSP 1 Score: 42.3578 bits (98), Expect = 2.170e-8
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D+W+VGC+M E+
Sbjct:  166 YRAPEVLLRSPVYSSPIDIWAVGCIMAEL 194

HSP 2 Score: 36.965 bits (84), Expect = 2.170e-8
Identity = 15/26 (57.69%), Postives = 22/26 (84.62%), Query Frame = -3 
Query:  638 IFSLRPLFPGANEVDQIGKIHDILGS 715
            +++LRPLFPG +EVD+I KI  +LG+
Sbjct:  194 LYTLRPLFPGNSEVDEIFKICQVLGT 219

HSP 3 Score: 41.5874 bits (96), Expect = 3.534e-6
Identity = 17/26 (65.38%), Postives = 21/26 (80.77%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            +KIADFG  + I SR PYT+Y+STRW
Sbjct:  140 VKIADFGLAREIRSRPPYTDYVSTRW 165

HSP 4 Score: 30.4166 bits (67), Expect = 3.534e-6
Identity = 13/40 (32.50%), Postives = 19/40 (47.50%), Query Frame = -1 
Query: 1987 FFYCFELFSLNSRNGIFHRDVKPENILIRVIIFFNYSRFG 2106
             F      +   ++G FHRD+KPEN+L         + FG
Sbjct:  107 MFQVLSGLAFVHKHGFFHRDMKPENLLCMGPELVKIADFG 146
[Close]
BLAST of SMED30006822 vs. Ensembl Zebrafish
Match: cdk11b (cyclin-dependent kinase 11B [Source:ZFIN;Acc:ZDB-GENE-041212-74])

HSP 1 Score: 38.5058 bits (88), Expect = 1.295e-7
Identity = 18/39 (46.15%), Postives = 25/39 (64.10%), Query Frame = -1 
Query:  727 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQWQKILY 843
            YR+P+ LL    YS  +D+WSVGC+  E+L    QK L+
Sbjct:  608 YRSPDLLLGAKEYSTAVDMWSVGCIFGELL---TQKPLF 643

HSP 2 Score: 38.1206 bits (87), Expect = 1.295e-7
Identity = 16/35 (45.71%), Postives = 22/35 (62.86%), Query Frame = -3 
Query:  611 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNF 715
            + + +PLFPG +E+DQI KI   LGSP   I   +
Sbjct:  636 LLTQKPLFPGKSEIDQINKIFKDLGSPSEKIWPGY 670
[Close]
BLAST of SMED30006822 vs. Ensembl Zebrafish
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741])

HSP 1 Score: 39.6614 bits (91), Expect = 1.763e-7
Identity = 16/30 (53.33%), Postives = 22/30 (73.33%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPE LL   YYS  +D+WS+GC+  E++
Sbjct:  168 YRAPEILLGCKYYSTAVDIWSLGCIFAEMI 197

HSP 2 Score: 36.5798 bits (83), Expect = 1.763e-7
Identity = 18/36 (50.00%), Postives = 25/36 (69.44%), Query Frame = -3 
Query:  623 IFKTLIFSLRPLFPGANEVDQIGKIHDILGSPDASI 730
            IF  +I + R LFPG +E+DQ+ +I   LG+PD SI
Sbjct:  192 IFAEMI-TRRALFPGDSEIDQLFRIFRTLGTPDESI 226
[Close]
BLAST of SMED30006822 vs. Ensembl Zebrafish
Match: cdk6 (cyclin-dependent kinase 6 [Source:ZFIN;Acc:ZDB-GENE-060503-786])

HSP 1 Score: 38.891 bits (89), Expect = 3.518e-7
Identity = 17/31 (54.84%), Postives = 21/31 (67.74%), Query Frame = -1 
Query:  751 YRAPECLLTDGYYSYQMDLWSVGCVMFEILR 843
            YRAPE LL   Y +  +DLWSVGC+  E+ R
Sbjct:  182 YRAPEVLLQSSYAT-PVDLWSVGCIFAEMFR 211

HSP 2 Score: 36.5798 bits (83), Expect = 3.518e-7
Identity = 15/27 (55.56%), Postives = 21/27 (77.78%), Query Frame = -3 
Query:  635 IFSLRPLFPGANEVDQIGKIHDILGSP 715
            +F  RPLF G ++VDQ+GKI D++G P
Sbjct:  209 MFRRRPLFRGNSDVDQLGKIFDVVGVP 235
[Close]
BLAST of SMED30006822 vs. Ensembl Xenopus
Match: ltb4r2 (leukotriene B4 receptor 2 [Source:Xenbase;Acc:XB-GENE-984956])

HSP 1 Score: 62.003 bits (149), Expect = 5.133e-20
Identity = 24/29 (82.76%), Postives = 27/29 (93.10%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPECLLTDGYY+Y+MD+WS GCV FEI
Sbjct:  167 YRAPECLLTDGYYTYKMDIWSAGCVFFEI 195

HSP 2 Score: 57.7658 bits (138), Expect = 5.133e-20
Identity = 23/37 (62.16%), Postives = 32/37 (86.49%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL PLFPG+NE+DQI KIHD++G+PD ++L+ FK+
Sbjct:  195 IASLHPLFPGSNELDQISKIHDVIGTPDQALLQKFKQ 231

HSP 3 Score: 52.373 bits (124), Expect = 5.377e-12
Identity = 19/26 (73.08%), Postives = 24/26 (92.31%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ DFGSC+++FS+ PYTEYISTRW
Sbjct:  141 LKLGDFGSCRSVFSKQPYTEYISTRW 166

HSP 4 Score: 40.0466 bits (92), Expect = 5.377e-12
Identity = 16/17 (94.12%), Postives = 17/17 (100.00%), Query Frame = -1 
Query: 2020 RNGIFHRDVKPENILIR 2070
            RNGIFHRDVKPENILI+
Sbjct:  121 RNGIFHRDVKPENILIK 137
[Close]
BLAST of SMED30006822 vs. Ensembl Xenopus
Match: ltb4r2 (leukotriene B4 receptor 2 [Source:Xenbase;Acc:XB-GENE-984956])

HSP 1 Score: 62.003 bits (149), Expect = 6.254e-20
Identity = 24/29 (82.76%), Postives = 27/29 (93.10%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPECLLTDGYY+Y+MD+WS GCV FEI
Sbjct:  170 YRAPECLLTDGYYTYKMDIWSAGCVFFEI 198

HSP 2 Score: 57.3806 bits (137), Expect = 6.254e-20
Identity = 23/37 (62.16%), Postives = 32/37 (86.49%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL PLFPG+NE+DQI KIHD++G+PD ++L+ FK+
Sbjct:  198 IASLHPLFPGSNELDQISKIHDVIGTPDQALLQKFKQ 234

HSP 3 Score: 52.373 bits (124), Expect = 6.232e-12
Identity = 19/26 (73.08%), Postives = 24/26 (92.31%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ DFGSC+++FS+ PYTEYISTRW
Sbjct:  144 LKLGDFGSCRSVFSKQPYTEYISTRW 169

HSP 4 Score: 40.0466 bits (92), Expect = 6.232e-12
Identity = 16/17 (94.12%), Postives = 17/17 (100.00%), Query Frame = -1 
Query: 2020 RNGIFHRDVKPENILIR 2070
            RNGIFHRDVKPENILI+
Sbjct:  124 RNGIFHRDVKPENILIK 140
[Close]
BLAST of SMED30006822 vs. Ensembl Xenopus
Match: ltb4r2 (leukotriene B4 receptor 2 [Source:Xenbase;Acc:XB-GENE-984956])

HSP 1 Score: 50.0618 bits (118), Expect = 3.137e-11
Identity = 19/26 (73.08%), Postives = 24/26 (92.31%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ DFGSC+++FS+ PYTEYISTRW
Sbjct:  141 LKLGDFGSCRSVFSKQPYTEYISTRW 166

HSP 2 Score: 39.6614 bits (91), Expect = 3.137e-11
Identity = 16/17 (94.12%), Postives = 17/17 (100.00%), Query Frame = -1 
Query: 2020 RNGIFHRDVKPENILIR 2070
            RNGIFHRDVKPENILI+
Sbjct:  121 RNGIFHRDVKPENILIK 137

HSP 3 Score: 63.929 bits (154), Expect = 5.936e-10
Identity = 25/31 (80.65%), Postives = 28/31 (90.32%), Query Frame = -1 
Query:  751 YRAPECLLTDGYYSYQMDLWSVGCVMFEILR 843
            YRAPECLLTDGYY+Y+MD+WS GCV FEI R
Sbjct:  167 YRAPECLLTDGYYTYKMDIWSAGCVFFEIAR 197
[Close]
BLAST of SMED30006822 vs. Ensembl Xenopus
Match: ICK (intestinal cell (MAK-like) kinase [Source:NCBI gene;Acc:100498050])

HSP 1 Score: 41.5874 bits (96), Expect = 9.251e-9
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    Y+  +D+W+VGC+M EI
Sbjct:  165 YRAPEVLLRATNYNSPIDIWAVGCIMAEI 193

HSP 2 Score: 39.6614 bits (91), Expect = 9.251e-9
Identity = 17/27 (62.96%), Postives = 23/27 (85.19%), Query Frame = -3 
Query:  635 IFSLRPLFPGANEVDQIGKIHDILGSP 715
            I++LRPLFPG++EVD I KI  +LG+P
Sbjct:  193 IYTLRPLFPGSSEVDTIFKICQVLGTP 219
[Close]
BLAST of SMED30006822 vs. Ensembl Xenopus
Match: ICK (intestinal cell (MAK-like) kinase [Source:NCBI gene;Acc:100498050])

HSP 1 Score: 41.2022 bits (95), Expect = 1.112e-8
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    Y+  +D+W+VGC+M EI
Sbjct:  165 YRAPEVLLRATNYNSPIDIWAVGCIMAEI 193

HSP 2 Score: 40.0466 bits (92), Expect = 1.112e-8
Identity = 17/27 (62.96%), Postives = 23/27 (85.19%), Query Frame = -3 
Query:  635 IFSLRPLFPGANEVDQIGKIHDILGSP 715
            I++LRPLFPG++EVD I KI  +LG+P
Sbjct:  193 IYTLRPLFPGSSEVDTIFKICQVLGTP 219
[Close]
BLAST of SMED30006822 vs. Ensembl Mouse
Match: Mok (MOK protein kinase [Source:MGI Symbol;Acc:MGI:1336881])

HSP 1 Score: 61.6178 bits (148), Expect = 1.307e-18
Identity = 24/33 (72.73%), Postives = 28/33 (84.85%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPECLLTDG+Y+Y+MDLWS GCV +EI   Q
Sbjct:  167 YRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQ 199

HSP 2 Score: 52.373 bits (124), Expect = 1.307e-18
Identity = 22/37 (59.46%), Postives = 28/37 (75.68%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL+PLFPG NE+DQI KIHD++G+P    L  FK+
Sbjct:  195 IASLQPLFPGVNELDQISKIHDVIGTPCQKTLTKFKQ 231

HSP 3 Score: 51.9878 bits (123), Expect = 5.214e-12
Identity = 18/26 (69.23%), Postives = 24/26 (92.31%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ DFGSC++++S+ PYTEYISTRW
Sbjct:  141 LKLGDFGSCRSVYSKQPYTEYISTRW 166

HSP 4 Score: 39.6614 bits (91), Expect = 5.214e-12
Identity = 17/32 (53.12%), Postives = 23/32 (71.88%), Query Frame = -1 
Query: 1975 RNGIFHRDVKPENILIRVIIFFNYSRFGNYFS 2070
            RNGIFHRDVKPENIL++  +     + G++ S
Sbjct:  121 RNGIFHRDVKPENILVKQDVL----KLGDFGS 148
[Close]
BLAST of SMED30006822 vs. Ensembl Mouse
Match: Mok (MOK protein kinase [Source:MGI Symbol;Acc:MGI:1336881])

HSP 1 Score: 48.9062 bits (115), Expect = 4.577e-11
Identity = 18/26 (69.23%), Postives = 24/26 (92.31%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ DFGSC++++S+ PYTEYISTRW
Sbjct:   49 LKLGDFGSCRSVYSKQPYTEYISTRW 74

HSP 2 Score: 39.6614 bits (91), Expect = 4.577e-11
Identity = 17/32 (53.12%), Postives = 23/32 (71.88%), Query Frame = -1 
Query: 1975 RNGIFHRDVKPENILIRVIIFFNYSRFGNYFS 2070
            RNGIFHRDVKPENIL++  +     + G++ S
Sbjct:   29 RNGIFHRDVKPENILVKQDVL----KLGDFGS 56

HSP 3 Score: 62.003 bits (149), Expect = 5.040e-10
Identity = 25/38 (65.79%), Postives = 30/38 (78.95%), Query Frame = -1 
Query:  730 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQWQKIL 843
            YRAPECLLTDG+Y+Y+MDLWS GCV +EI R    + L
Sbjct:   75 YRAPECLLTDGFYTYKMDLWSAGCVFYEIARAAETQTL 112
[Close]
BLAST of SMED30006822 vs. Ensembl Mouse
Match: Ick (intestinal cell kinase [Source:MGI Symbol;Acc:MGI:1934157])

HSP 1 Score: 42.743 bits (99), Expect = 2.194e-9
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D+W+VGC+M E+
Sbjct:  165 YRAPEVLLRSTNYSSPIDIWAVGCIMAEV 193

HSP 2 Score: 40.0466 bits (92), Expect = 2.194e-9
Identity = 16/30 (53.33%), Postives = 24/30 (80.00%), Query Frame = -3 
Query:  626 IFSLRPLFPGANEVDQIGKIHDILGSPDAS 715
            +++LRPLFPGA+E+D I KI  +LG+P  +
Sbjct:  193 VYTLRPLFPGASEIDTIFKICQVLGTPKKT 222

HSP 3 Score: 43.1282 bits (100), Expect = 1.876e-6
Identity = 21/46 (45.65%), Postives = 30/46 (65.22%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  + I SR PYT+Y+STRW      L +  ++Y +P+ I
Sbjct:  139 VKIADFGLAREIRSRPPYTDYVSTRWYRAPEVL-LRSTNYSSPIDI 183

HSP 4 Score: 29.6462 bits (65), Expect = 1.876e-6
Identity = 10/15 (66.67%), Postives = 14/15 (93.33%), Query Frame = -1 
Query: 2026 RNGIFHRDVKPENIL 2070
            ++G FHRD+KPEN+L
Sbjct:  118 KHGFFHRDLKPENLL 132
[Close]
BLAST of SMED30006822 vs. Ensembl Mouse
Match: Ick (intestinal cell kinase [Source:MGI Symbol;Acc:MGI:1934157])

HSP 1 Score: 42.743 bits (99), Expect = 2.445e-9
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D+W+VGC+M E+
Sbjct:  165 YRAPEVLLRSTNYSSPIDIWAVGCIMAEV 193

HSP 2 Score: 40.0466 bits (92), Expect = 2.445e-9
Identity = 16/30 (53.33%), Postives = 24/30 (80.00%), Query Frame = -3 
Query:  626 IFSLRPLFPGANEVDQIGKIHDILGSPDAS 715
            +++LRPLFPGA+E+D I KI  +LG+P  +
Sbjct:  193 VYTLRPLFPGASEIDTIFKICQVLGTPKKT 222

HSP 3 Score: 43.5134 bits (101), Expect = 1.692e-6
Identity = 21/46 (45.65%), Postives = 30/46 (65.22%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  + I SR PYT+Y+STRW      L +  ++Y +P+ I
Sbjct:  139 VKIADFGLAREIRSRPPYTDYVSTRWYRAPEVL-LRSTNYSSPIDI 183

HSP 4 Score: 29.6462 bits (65), Expect = 1.692e-6
Identity = 10/15 (66.67%), Postives = 14/15 (93.33%), Query Frame = -1 
Query: 2026 RNGIFHRDVKPENIL 2070
            ++G FHRD+KPEN+L
Sbjct:  118 KHGFFHRDLKPENLL 132
[Close]
BLAST of SMED30006822 vs. Ensembl Mouse
Match: Ick (intestinal cell kinase [Source:MGI Symbol;Acc:MGI:1934157])

HSP 1 Score: 42.743 bits (99), Expect = 2.445e-9
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D+W+VGC+M E+
Sbjct:  165 YRAPEVLLRSTNYSSPIDIWAVGCIMAEV 193

HSP 2 Score: 40.0466 bits (92), Expect = 2.445e-9
Identity = 16/30 (53.33%), Postives = 24/30 (80.00%), Query Frame = -3 
Query:  626 IFSLRPLFPGANEVDQIGKIHDILGSPDAS 715
            +++LRPLFPGA+E+D I KI  +LG+P  +
Sbjct:  193 VYTLRPLFPGASEIDTIFKICQVLGTPKKT 222

HSP 3 Score: 43.5134 bits (101), Expect = 1.692e-6
Identity = 21/46 (45.65%), Postives = 30/46 (65.22%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  + I SR PYT+Y+STRW      L +  ++Y +P+ I
Sbjct:  139 VKIADFGLAREIRSRPPYTDYVSTRWYRAPEVL-LRSTNYSSPIDI 183

HSP 4 Score: 29.6462 bits (65), Expect = 1.692e-6
Identity = 10/15 (66.67%), Postives = 14/15 (93.33%), Query Frame = -1 
Query: 2026 RNGIFHRDVKPENIL 2070
            ++G FHRD+KPEN+L
Sbjct:  118 KHGFFHRDLKPENLL 132
[Close]
BLAST of SMED30006822 vs. UniProt/SwissProt
Match: sp|Q9UQ07|MOK_HUMAN (MAPK/MAK/MRK overlapping kinase OS=Homo sapiens OX=9606 GN=MOK PE=2 SV=1)

HSP 1 Score: 61.6178 bits (148), Expect = 2.572e-18
Identity = 24/33 (72.73%), Postives = 28/33 (84.85%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPECLLTDG+Y+Y+MDLWS GCV +EI   Q
Sbjct:  167 YRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQ 199

HSP 2 Score: 53.9138 bits (128), Expect = 2.572e-18
Identity = 23/37 (62.16%), Postives = 29/37 (78.38%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL+PLFPG NE+DQI KIHD++G+P   IL  FK+
Sbjct:  195 IASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQ 231

HSP 3 Score: 51.9878 bits (123), Expect = 2.280e-11
Identity = 18/26 (69.23%), Postives = 24/26 (92.31%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ DFGSC++++S+ PYTEYISTRW
Sbjct:  141 LKLGDFGSCRSVYSKQPYTEYISTRW 166

HSP 4 Score: 40.0466 bits (92), Expect = 2.280e-11
Identity = 18/32 (56.25%), Postives = 23/32 (71.88%), Query Frame = -1 
Query: 1975 RNGIFHRDVKPENILIRVIIFFNYSRFGNYFS 2070
            RNGIFHRDVKPENILI+  +     + G++ S
Sbjct:  121 RNGIFHRDVKPENILIKQDVL----KLGDFGS 148
[Close]
BLAST of SMED30006822 vs. UniProt/SwissProt
Match: sp|Q9WVS4|MOK_MOUSE (MAPK/MAK/MRK overlapping kinase OS=Mus musculus OX=10090 GN=Mok PE=1 SV=1)

HSP 1 Score: 61.6178 bits (148), Expect = 7.976e-18
Identity = 24/33 (72.73%), Postives = 28/33 (84.85%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPECLLTDG+Y+Y+MDLWS GCV +EI   Q
Sbjct:  167 YRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQ 199

HSP 2 Score: 52.373 bits (124), Expect = 7.976e-18
Identity = 22/37 (59.46%), Postives = 28/37 (75.68%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL+PLFPG NE+DQI KIHD++G+P    L  FK+
Sbjct:  195 IASLQPLFPGVNELDQISKIHDVIGTPCQKTLTKFKQ 231

HSP 3 Score: 51.9878 bits (123), Expect = 3.184e-11
Identity = 18/26 (69.23%), Postives = 24/26 (92.31%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ DFGSC++++S+ PYTEYISTRW
Sbjct:  141 LKLGDFGSCRSVYSKQPYTEYISTRW 166

HSP 4 Score: 39.6614 bits (91), Expect = 3.184e-11
Identity = 17/32 (53.12%), Postives = 23/32 (71.88%), Query Frame = -1 
Query: 1975 RNGIFHRDVKPENILIRVIIFFNYSRFGNYFS 2070
            RNGIFHRDVKPENIL++  +     + G++ S
Sbjct:  121 RNGIFHRDVKPENILVKQDVL----KLGDFGS 148
[Close]
BLAST of SMED30006822 vs. UniProt/SwissProt
Match: sp|O43077|MDE3_SCHPO (Sporulation protein kinase mde3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mde3 PE=3 SV=1)

HSP 1 Score: 42.743 bits (99), Expect = 3.079e-9
Identity = 16/29 (55.17%), Postives = 23/29 (79.31%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL  G Y++ +DL++ GC++FEI
Sbjct:  198 YRAPELLLRSGSYNHSVDLYAFGCIVFEI 226

HSP 2 Score: 42.3578 bits (98), Expect = 3.079e-9
Identity = 16/27 (59.26%), Postives = 23/27 (85.19%), Query Frame = -3 
Query:  635 IFSLRPLFPGANEVDQIGKIHDILGSP 715
            I+SL+PLFPG NE DQ+ ++ +ILG+P
Sbjct:  226 IYSLKPLFPGRNETDQLNRVCEILGNP 252
[Close]
BLAST of SMED30006822 vs. UniProt/SwissProt
Match: sp|O14132|PIT1_SCHPO (Sporulation protein kinase pit1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=pit1 PE=1 SV=1)

HSP 1 Score: 46.9802 bits (110), Expect = 3.216e-9
Identity = 18/33 (54.55%), Postives = 24/33 (72.73%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPE LL D YYS+ +D+++ GC+ FEI   Q
Sbjct:  206 YRAPELLLRDSYYSFPVDIYAAGCMAFEIATLQ 238

HSP 2 Score: 37.7354 bits (86), Expect = 3.216e-9
Identity = 15/28 (53.57%), Postives = 23/28 (82.14%), Query Frame = -3 
Query:  632 IFSLRPLFPGANEVDQIGKIHDILGSPD 715
            I +L+P+FPG ++ DQ+ K+ +ILGSPD
Sbjct:  234 IATLQPIFPGNDDFDQLYKMCEILGSPD 261

HSP 3 Score: 45.4394 bits (106), Expect = 1.129e-7
Identity = 24/47 (51.06%), Postives = 30/47 (63.83%), Query Frame = -3 
Query: 1817 SLKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1957
            ++KIADFG  + I SR PYTEY+STRW      L  + S+Y  PV I
Sbjct:  179 NVKIADFGLAREINSRPPYTEYVSTRWYRAPELLLRD-SYYSFPVDI 224

HSP 4 Score: 34.2686 bits (77), Expect = 1.129e-7
Identity = 13/15 (86.67%), Postives = 14/15 (93.33%), Query Frame = -1 
Query: 2023 NGIFHRDVKPENILI 2067
            NG FHRD+KPENILI
Sbjct:  155 NGFFHRDMKPENILI 169
[Close]
BLAST of SMED30006822 vs. UniProt/SwissProt
Match: sp|P32581|IME2_YEAST (Meiosis induction protein kinase IME2/SME1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=IME2 PE=3 SV=1)

HSP 1 Score: 44.669 bits (104), Expect = 5.962e-9
Identity = 17/33 (51.52%), Postives = 23/33 (69.70%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YR+PE LL  GYYS  +D+W+ GCV  E+  F+
Sbjct:  250 YRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFR 282

HSP 2 Score: 39.2762 bits (90), Expect = 5.962e-9
Identity = 16/24 (66.67%), Postives = 20/24 (83.33%), Query Frame = -3 
Query:  635 LRPLFPGANEVDQIGKIHDILGSP 706
             R LFPGANE+DQI KI ++LG+P
Sbjct:  281 FRALFPGANEIDQIWKILEVLGTP 304
[Close]
BLAST of SMED30006822 vs. TrEMBL
Match: W4Z737 (Protein kinase domain-containing protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 1.515e-20
Identity = 31/43 (72.09%), Postives = 34/43 (79.07%), Query Frame = -1 
Query:  754 SKLSFKIKIYHKRYRAPECLLTDGYYSYQMDLWSVGCVMFEIL 882
            SK  F   I  + YRAPECLLTDGYYSYQMD+WSVGCV +EIL
Sbjct:  120 SKQPFTEYISTRWYRAPECLLTDGYYSYQMDMWSVGCVFYEIL 162

HSP 2 Score: 63.1586 bits (152), Expect = 1.515e-20
Identity = 26/36 (72.22%), Postives = 31/36 (86.11%), Query Frame = -3 
Query:  608 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFK 715
            I SL PLFPGANEVDQI KIHD++G+PDA+IL  F+
Sbjct:  161 ILSLHPLFPGANEVDQIAKIHDVMGTPDATILNKFR 196

HSP 3 Score: 53.9138 bits (128), Expect = 5.527e-10
Identity = 19/29 (65.52%), Postives = 26/29 (89.66%), Query Frame = -3 
Query: 1877 DQSLKIADFGSCKTIFSRYPYTEYISTRW 1963
            D  LK+ADFGSC++++S+ P+TEYISTRW
Sbjct:  104 DDHLKLADFGSCRSVYSKQPFTEYISTRW 132

HSP 4 Score: 41.9726 bits (97), Expect = 5.527e-10
Identity = 17/17 (100.00%), Postives = 17/17 (100.00%), Query Frame = -1 
Query: 2020 RNGIFHRDVKPENILIR 2070
            RNGIFHRDVKPENILIR
Sbjct:   87 RNGIFHRDVKPENILIR 103
[Close]
BLAST of SMED30006822 vs. TrEMBL
Match: A0A210QFC8 (MAPK/MAK/MRK overlapping kinase OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT10324 PE=4 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 7.294e-20
Identity = 26/33 (78.79%), Postives = 29/33 (87.88%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPECLLTDGYY+Y+MD+WSVGCV FEIL   
Sbjct:  558 YRAPECLLTDGYYTYKMDIWSVGCVFFEILSLH 590

HSP 2 Score: 62.3882 bits (150), Expect = 7.294e-20
Identity = 27/37 (72.97%), Postives = 30/37 (81.08%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL PLFPG+NEVDQI KIHDILG+PD S+L   KK
Sbjct:  586 ILSLHPLFPGSNEVDQIAKIHDILGTPDPSVLNKLKK 622

HSP 3 Score: 53.9138 bits (128), Expect = 7.483e-10
Identity = 19/26 (73.08%), Postives = 25/26 (96.15%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ADFGSC++++S+ PYTEYISTRW
Sbjct:  532 LKLADFGSCRSVYSKQPYTEYISTRW 557

HSP 4 Score: 41.2022 bits (95), Expect = 7.483e-10
Identity = 16/17 (94.12%), Postives = 17/17 (100.00%), Query Frame = -1 
Query: 2020 RNGIFHRDVKPENILIR 2070
            RNGIFHRDVKPENILI+
Sbjct:  512 RNGIFHRDVKPENILIK 528
[Close]
BLAST of SMED30006822 vs. TrEMBL
Match: H2YWW9 (Protein kinase domain-containing protein OS=Ciona savignyi OX=51511 PE=4 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 1.150e-19
Identity = 28/46 (60.87%), Postives = 35/46 (76.09%), Query Frame = -1 
Query:  745 SKLSFKIKIYHKRYRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 882
            SK  +   I  + YRAPECLLTDGYY+Y+MDLWSVGCV+FE++   
Sbjct:  147 SKQPYTEYISTRWYRAPECLLTDGYYTYRMDLWSVGCVLFEVMSLH 192

HSP 2 Score: 63.929 bits (154), Expect = 1.150e-19
Identity = 26/37 (70.27%), Postives = 31/37 (83.78%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            + SL PLFPGANEVDQI KIHD+LG+PDAS+L   K+
Sbjct:  188 VMSLHPLFPGANEVDQISKIHDVLGTPDASVLNKMKQ 224

HSP 3 Score: 54.6842 bits (130), Expect = 1.225e-8
Identity = 20/29 (68.97%), Postives = 26/29 (89.66%), Query Frame = -3 
Query: 1877 DQSLKIADFGSCKTIFSRYPYTEYISTRW 1963
            D  LK+ADFGSC++++S+ PYTEYISTRW
Sbjct:  131 DDVLKLADFGSCRSVYSKQPYTEYISTRW 159

HSP 4 Score: 36.1946 bits (82), Expect = 1.225e-8
Identity = 15/17 (88.24%), Postives = 16/17 (94.12%), Query Frame = -1 
Query: 2020 RNGIFHRDVKPENILIR 2070
            R GIFHRDVKPENILI+
Sbjct:  114 RCGIFHRDVKPENILIK 130
[Close]
BLAST of SMED30006822 vs. TrEMBL
Match: A0A3Q0JV15 (MAPK/MAK/MRK overlapping kinase OS=Ciona intestinalis OX=7719 GN=LOC100186816 PE=4 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 1.748e-19
Identity = 25/30 (83.33%), Postives = 30/30 (100.00%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPECLLTDGYY+Y+MDLWSVGCV+FE++
Sbjct:  196 YRAPECLLTDGYYTYRMDLWSVGCVLFEVM 225

HSP 2 Score: 62.003 bits (149), Expect = 1.748e-19
Identity = 27/36 (75.00%), Postives = 30/36 (83.33%), Query Frame = -3 
Query:  608 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFK 715
            + SL PLFPGANEVDQI KIHD+LG+PDASIL   K
Sbjct:  224 VMSLHPLFPGANEVDQISKIHDVLGTPDASILNKMK 259

HSP 3 Score: 54.6842 bits (130), Expect = 1.769e-8
Identity = 20/29 (68.97%), Postives = 26/29 (89.66%), Query Frame = -3 
Query: 1877 DQSLKIADFGSCKTIFSRYPYTEYISTRW 1963
            D  LK+ADFGSC++++S+ PYTEYISTRW
Sbjct:  167 DDVLKLADFGSCRSVYSKQPYTEYISTRW 195

HSP 4 Score: 35.8094 bits (81), Expect = 1.769e-8
Identity = 15/17 (88.24%), Postives = 16/17 (94.12%), Query Frame = -1 
Query: 2020 RNGIFHRDVKPENILIR 2070
            R GIFHRDVKPENILI+
Sbjct:  150 RCGIFHRDVKPENILIK 166
[Close]
BLAST of SMED30006822 vs. TrEMBL
Match: K1QVT7 (MAPK/MAK/MRK overlapping kinase OS=Crassostrea gigas OX=29159 GN=CGI_10017610 PE=4 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 2.617e-19
Identity = 26/30 (86.67%), Postives = 29/30 (96.67%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPECLLTDGYY+Y+MD+WSVGCV FEIL
Sbjct:  172 YRAPECLLTDGYYTYKMDIWSVGCVFFEIL 201

HSP 2 Score: 61.6178 bits (148), Expect = 2.617e-19
Identity = 26/37 (70.27%), Postives = 31/37 (83.78%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL PLFPG+NEVDQI KIHDI+G+PD+S+L   KK
Sbjct:  200 ILSLHPLFPGSNEVDQIAKIHDIMGTPDSSVLDKLKK 236

HSP 3 Score: 53.1434 bits (126), Expect = 7.807e-10
Identity = 19/26 (73.08%), Postives = 25/26 (96.15%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ADFGSC++++S+ PYTEYISTRW
Sbjct:  146 LKLADFGSCRSVYSKQPYTEYISTRW 171

HSP 4 Score: 41.5874 bits (96), Expect = 7.807e-10
Identity = 17/17 (100.00%), Postives = 17/17 (100.00%), Query Frame = -1 
Query: 2020 RNGIFHRDVKPENILIR 2070
            RNGIFHRDVKPENILIR
Sbjct:  126 RNGIFHRDVKPENILIR 142
[Close]
BLAST of SMED30006822 vs. Ensembl Cavefish
Match: MOK (MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:9833])

HSP 1 Score: 60.8474 bits (146), Expect = 2.641e-20
Identity = 24/30 (80.00%), Postives = 27/30 (90.00%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPECLLTDGYYS +MD+WS GCV FEI+
Sbjct:  170 YRAPECLLTDGYYSLKMDIWSAGCVFFEIM 199

HSP 2 Score: 58.9214 bits (141), Expect = 2.641e-20
Identity = 23/37 (62.16%), Postives = 32/37 (86.49%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL PLFPG+NEVDQ+ KIHD+LG+P++ +L+ FK+
Sbjct:  198 IMSLNPLFPGSNEVDQVSKIHDVLGTPESMVLQKFKQ 234

HSP 3 Score: 50.447 bits (119), Expect = 4.788e-11
Identity = 18/26 (69.23%), Postives = 25/26 (96.15%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ADFGSC++++S+ P+TEYISTRW
Sbjct:  144 LKLADFGSCRSVYSKPPHTEYISTRW 169

HSP 4 Score: 37.7354 bits (86), Expect = 4.788e-11
Identity = 15/16 (93.75%), Postives = 16/16 (100.00%), Query Frame = -1 
Query: 2020 NGIFHRDVKPENILIR 2067
            NGIFHRDVKPENILI+
Sbjct:  125 NGIFHRDVKPENILIK 140
[Close]
BLAST of SMED30006822 vs. Ensembl Cavefish
Match: ICK (serine/threonine-protein kinase ICK-like [Source:NCBI gene;Acc:103040253])

HSP 1 Score: 40.4318 bits (93), Expect = 8.814e-9
Identity = 16/29 (55.17%), Postives = 20/29 (68.97%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D W+VGC+M E+
Sbjct:  165 YRAPEVLLRSTSYSSPIDQWAVGCIMAEL 193

HSP 2 Score: 40.0466 bits (92), Expect = 8.814e-9
Identity = 17/27 (62.96%), Postives = 23/27 (85.19%), Query Frame = -3 
Query:  635 IFSLRPLFPGANEVDQIGKIHDILGSP 715
            ++SLRPLFPG++EVD I KI  +LG+P
Sbjct:  193 LYSLRPLFPGSSEVDTIFKICQVLGTP 219

HSP 3 Score: 41.9726 bits (97), Expect = 1.880e-6
Identity = 21/44 (47.73%), Postives = 28/44 (63.64%), Query Frame = -3 
Query: 1823 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPV 1954
            +KIADFG  + I SR PYT+Y+STRW      L  + S Y +P+
Sbjct:  139 VKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTS-YSSPI 181

HSP 4 Score: 30.8018 bits (68), Expect = 1.880e-6
Identity = 13/40 (32.50%), Postives = 20/40 (50.00%), Query Frame = -1 
Query: 1987 FFYCFELFSLNSRNGIFHRDVKPENILIRVIIFFNYSRFG 2106
             F   +  +   ++G FHRD+KPEN+L         + FG
Sbjct:  106 MFQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFG 145
[Close]
BLAST of SMED30006822 vs. Ensembl Cavefish
Match: ICK (serine/threonine-protein kinase ICK-like [Source:NCBI gene;Acc:103040253])

HSP 1 Score: 40.0466 bits (92), Expect = 1.004e-8
Identity = 16/29 (55.17%), Postives = 20/29 (68.97%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D W+VGC+M E+
Sbjct:  165 YRAPEVLLRSTSYSSPIDQWAVGCIMAEL 193

HSP 2 Score: 40.0466 bits (92), Expect = 1.004e-8
Identity = 17/27 (62.96%), Postives = 23/27 (85.19%), Query Frame = -3 
Query:  635 IFSLRPLFPGANEVDQIGKIHDILGSP 715
            ++SLRPLFPG++EVD I KI  +LG+P
Sbjct:  193 LYSLRPLFPGSSEVDTIFKICQVLGTP 219

HSP 3 Score: 41.5874 bits (96), Expect = 2.268e-6
Identity = 21/44 (47.73%), Postives = 28/44 (63.64%), Query Frame = -3 
Query: 1823 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPV 1954
            +KIADFG  + I SR PYT+Y+STRW      L  + S Y +P+
Sbjct:  139 VKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTS-YSSPI 181

HSP 4 Score: 30.4166 bits (67), Expect = 2.268e-6
Identity = 13/40 (32.50%), Postives = 20/40 (50.00%), Query Frame = -1 
Query: 1987 FFYCFELFSLNSRNGIFHRDVKPENILIRVIIFFNYSRFG 2106
             F   +  +   ++G FHRD+KPEN+L         + FG
Sbjct:  106 MFQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFG 145
[Close]
BLAST of SMED30006822 vs. Ensembl Cavefish
Match: mak (male germ cell associated kinase [Source:NCBI gene;Acc:103025131])

HSP 1 Score: 43.1282 bits (100), Expect = 1.260e-8
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D+W+VGC+M E+
Sbjct:  131 YRAPEVLLRSSMYSSPIDMWAVGCIMAEL 159

HSP 2 Score: 36.5798 bits (83), Expect = 1.260e-8
Identity = 15/26 (57.69%), Postives = 22/26 (84.62%), Query Frame = -3 
Query:  638 IFSLRPLFPGANEVDQIGKIHDILGS 715
            +++LRPLFPG +EVD+I KI  +LG+
Sbjct:  159 LYTLRPLFPGNSEVDEIFKICQVLGT 184

HSP 3 Score: 41.2022 bits (95), Expect = 2.089e-6
Identity = 20/46 (43.48%), Postives = 28/46 (60.87%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  +   SR PYT+Y+STRW      L +  S Y +P+ +
Sbjct:  105 VKIADFGLARETRSRPPYTDYVSTRWYRAPEVL-LRSSMYSSPIDM 149

HSP 4 Score: 31.187 bits (69), Expect = 2.089e-6
Identity = 14/39 (35.90%), Postives = 20/39 (51.28%), Query Frame = -1 
Query: 1987 FYCFELFSLNSRNGIFHRDVKPENILIRVIIFFNYSRFG 2103
            F   +  S   ++G FHRD+KPEN+L         + FG
Sbjct:   73 FQILQGLSFIHKHGFFHRDMKPENLLCMGPELVKIADFG 111
[Close]
BLAST of SMED30006822 vs. Ensembl Cavefish
Match: mak (male germ cell associated kinase [Source:NCBI gene;Acc:103025131])

HSP 1 Score: 43.1282 bits (100), Expect = 1.270e-8
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D+W+VGC+M E+
Sbjct:  132 YRAPEVLLRSSMYSSPIDMWAVGCIMAEL 160

HSP 2 Score: 36.965 bits (84), Expect = 1.270e-8
Identity = 15/26 (57.69%), Postives = 22/26 (84.62%), Query Frame = -3 
Query:  638 IFSLRPLFPGANEVDQIGKIHDILGS 715
            +++LRPLFPG +EVD+I KI  +LG+
Sbjct:  160 LYTLRPLFPGNSEVDEIFKICQVLGT 185

HSP 3 Score: 41.2022 bits (95), Expect = 5.186e-6
Identity = 20/46 (43.48%), Postives = 28/46 (60.87%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  +   SR PYT+Y+STRW      L +  S Y +P+ +
Sbjct:  106 VKIADFGLARETRSRPPYTDYVSTRWYRAPEVL-LRSSMYSSPIDM 150

HSP 4 Score: 30.0314 bits (66), Expect = 5.186e-6
Identity = 12/28 (42.86%), Postives = 17/28 (60.71%), Query Frame = -1 
Query: 1987 RNGIFHRDVKPENILIRVIIFFNYSRFG 2070
            ++G FHRD+KPEN+L         + FG
Sbjct:   85 KHGFFHRDMKPENLLCMGPELVKIADFG 112
[Close]
BLAST of SMED30006822 vs. Ensembl Sea Lamprey
Match: mak (male germ cell-associated kinase [Source:ZFIN;Acc:ZDB-GENE-030131-7279])

HSP 1 Score: 41.2022 bits (95), Expect = 2.423e-9
Identity = 17/27 (62.96%), Postives = 24/27 (88.89%), Query Frame = -3 
Query:  635 IFSLRPLFPGANEVDQIGKIHDILGSP 715
            +++LRPLFPG++EVDQI KI  +LG+P
Sbjct:  193 LYTLRPLFPGSSEVDQIFKICQVLGTP 219

HSP 2 Score: 38.891 bits (89), Expect = 2.423e-9
Identity = 15/43 (34.88%), Postives = 26/43 (60.47%), Query Frame = -1 
Query:  757 KSKLSFKIKIYHKRYRAPECLLTDGYYSYQMDLWSVGCVMFEI 885
            +S+  +   +  + YR PE LL    YS  +D+W++GC+M E+
Sbjct:  151 RSRPPYTDYVSTRWYRGPEVLLRSTSYSSPIDIWALGCIMAEL 193

HSP 3 Score: 42.3578 bits (98), Expect = 4.763e-7
Identity = 22/46 (47.83%), Postives = 29/46 (63.04%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  + I SR PYT+Y+STRW      L  + S Y +P+ I
Sbjct:  139 VKIADFGLAREIRSRPPYTDYVSTRWYRGPEVLLRSTS-YSSPIDI 183

HSP 4 Score: 29.6462 bits (65), Expect = 4.763e-7
Identity = 12/28 (42.86%), Postives = 17/28 (60.71%), Query Frame = -1 
Query: 1987 RNGIFHRDVKPENILIRVIIFFNYSRFG 2070
            ++G FHRD+KPEN+L         + FG
Sbjct:  118 KHGFFHRDMKPENLLCMGPELVKIADFG 145
[Close]
BLAST of SMED30006822 vs. Ensembl Sea Lamprey
Match: mapk1 (mitogen-activated protein kinase 1 [Source:ZFIN;Acc:ZDB-GENE-030722-2])

HSP 1 Score: 40.0466 bits (92), Expect = 1.579e-7
Identity = 15/30 (50.00%), Postives = 22/30 (73.33%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPE +L    Y+  +D+WSVGC++ E+L
Sbjct:  204 YRAPEIMLNSKGYTKSIDIWSVGCILAEML 233

HSP 2 Score: 33.4982 bits (75), Expect = 1.579e-7
Identity = 16/32 (50.00%), Postives = 20/32 (62.50%), Query Frame = -3 
Query:  620 IFSLRPLFPGANEVDQIGKIHDILGSPDASIL 715
            + S RPLFPG + +DQ+  I  ILGSP    L
Sbjct:  232 MLSNRPLFPGKHYLDQLNHILGILGSPSQEDL 263
[Close]
BLAST of SMED30006822 vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741])

HSP 1 Score: 40.0466 bits (92), Expect = 2.134e-7
Identity = 16/30 (53.33%), Postives = 22/30 (73.33%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPE LL   +YS  +D+WS+GC+  E+L
Sbjct:  168 YRAPEILLGCKHYSTSVDVWSIGCIFAEML 197

HSP 2 Score: 33.4982 bits (75), Expect = 2.134e-7
Identity = 13/31 (41.94%), Postives = 21/31 (67.74%), Query Frame = -3 
Query:  623 IFSLRPLFPGANEVDQIGKIHDILGSPDASI 715
            + + R LFPG +E+DQ+ +I   LG+PD  +
Sbjct:  196 MLTRRALFPGDSEIDQLFRIFRTLGTPDEVV 226
[Close]
BLAST of SMED30006822 vs. Ensembl Sea Lamprey
Match: cdk4 (cyclin-dependent kinase 4 [Source:ZFIN;Acc:ZDB-GENE-060929-974])

HSP 1 Score: 38.1206 bits (87), Expect = 4.952e-7
Identity = 17/31 (54.84%), Postives = 21/31 (67.74%), Query Frame = -1 
Query:  751 YRAPECLLTDGYYSYQMDLWSVGCVMFEILR 843
            YRAPE LL   Y +  +DLWSVGC+  E+ R
Sbjct:  187 YRAPEVLLQSSYAT-TVDLWSVGCIFAEMFR 216

HSP 2 Score: 33.8834 bits (76), Expect = 4.952e-7
Identity = 14/28 (50.00%), Postives = 21/28 (75.00%), Query Frame = -3 
Query:  632 IFSLRPLFPGANEVDQIGKIHDILGSPD 715
            +F  RPLF G+++ DQ+ KI D+LG P+
Sbjct:  214 MFRRRPLFCGSSDFDQLTKIFDLLGLPN 241
[Close]
BLAST of SMED30006822 vs. Ensembl Sea Lamprey
Match: cdk1 (cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GENE-010320-1])

HSP 1 Score: 38.1206 bits (87), Expect = 1.913e-6
Identity = 15/30 (50.00%), Postives = 21/30 (70.00%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPE LL    YS  +D+WSVG ++ E++
Sbjct:  159 YRAPEVLLGTPRYSTPVDMWSVGTILAEMV 188

HSP 2 Score: 31.9574 bits (71), Expect = 1.913e-6
Identity = 13/27 (48.15%), Postives = 19/27 (70.37%), Query Frame = -3 
Query:  623 RPLFPGANEVDQIGKIHDILGSPDASI 703
            RPLF G +E+DQ+ +I  ILG+P   +
Sbjct:  191 RPLFHGDSEIDQLFRIFRILGTPTTEV 217
[Close]
BLAST of SMED30006822 vs. Ensembl Yeast
Match: IME2 (Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642])

HSP 1 Score: 44.669 bits (104), Expect = 1.066e-10
Identity = 17/33 (51.52%), Postives = 23/33 (69.70%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YR+PE LL  GYYS  +D+W+ GCV  E+  F+
Sbjct:  250 YRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFR 282

HSP 2 Score: 39.2762 bits (90), Expect = 1.066e-10
Identity = 16/24 (66.67%), Postives = 20/24 (83.33%), Query Frame = -3 
Query:  635 LRPLFPGANEVDQIGKIHDILGSP 706
             R LFPGANE+DQI KI ++LG+P
Sbjct:  281 FRALFPGANEIDQIWKILEVLGTP 304
[Close]
BLAST of SMED30006822 vs. Ensembl Yeast
Match: SMK1 (Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p [Source:SGD;Acc:S000006258])

HSP 1 Score: 40.4318 bits (93), Expect = 8.235e-7
Identity = 15/28 (53.57%), Postives = 22/28 (78.57%), Query Frame = -1 
Query:  760 YRAPECLLTDGYYSYQMDLWSVGCVMFE 843
            YRAPE LL++  YS  +D+W+VGC++ E
Sbjct:  215 YRAPELLLSNQPYSKSVDIWAVGCILAE 242

HSP 2 Score: 30.4166 bits (67), Expect = 8.235e-7
Identity = 13/34 (38.24%), Postives = 22/34 (64.71%), Query Frame = -3 
Query:  611 FSLRPLFPGANEVDQIGKIHDILGSPDASILKNF 712
            ++ +P+F G + + QI +I  +LG+PD  IL  F
Sbjct:  244 YARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKF 277
[Close]
BLAST of SMED30006822 vs. Ensembl Yeast
Match: SSN3 (Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963])

HSP 1 Score: 42.743 bits (99), Expect = 1.173e-6
Identity = 17/33 (51.52%), Postives = 23/33 (69.70%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPE LL   +Y+  +DLWSVGC+  E++  Q
Sbjct:  330 YRAPELLLGARHYTPAVDLWSVGCIFAELIGLQ 362

HSP 2 Score: 27.335 bits (59), Expect = 1.173e-6
Identity = 17/53 (32.08%), Postives = 27/53 (50.94%), Query Frame = -3 
Query:  605 IFKTLIFSLRPLFPGAN-----------EVDQIGKIHDILGSPDASILKNFKK 730
            IF  LI  L+P+F G             +V+Q+ +I ++LG+PD  I    +K
Sbjct:  354 IFAELI-GLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEK 405
[Close]
BLAST of SMED30006822 vs. Ensembl Yeast
Match: CDC28 (Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364])

HSP 1 Score: 37.3502 bits (85), Expect = 1.342e-6
Identity = 15/29 (51.72%), Postives = 19/29 (65.52%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D WS+GC+  E+
Sbjct:  177 YRAPEVLLGGKQYSTGVDTWSIGCIFAEM 205

HSP 2 Score: 32.3426 bits (72), Expect = 1.342e-6
Identity = 13/27 (48.15%), Postives = 21/27 (77.78%), Query Frame = -3 
Query:  623 RPLFPGANEVDQIGKIHDILGSPDASI 703
            +P+F G +E+DQI KI  +LG+P+ +I
Sbjct:  209 KPIFSGDSEIDQIFKIFRVLGTPNEAI 235
[Close]
BLAST of SMED30006822 vs. Ensembl Yeast
Match: RIM11 (Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004747])

HSP 1 Score: 40.4318 bits (93), Expect = 1.890e-6
Identity = 16/30 (53.33%), Postives = 21/30 (70.00%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPE +     Y+ Q+D+WS GCVM E+L
Sbjct:  205 YRAPELIFGATNYTNQIDIWSSGCVMAELL 234

HSP 2 Score: 29.261 bits (64), Expect = 1.890e-6
Identity = 11/23 (47.83%), Postives = 18/23 (78.26%), Query Frame = -3 
Query:  635 RPLFPGANEVDQIGKIHDILGSP 703
            +P+FPG + +DQ+ +I  ILG+P
Sbjct:  237 QPMFPGESGIDQLVEIIKILGTP 259
[Close]
BLAST of SMED30006822 vs. Ensembl Nematostella
Match: EDO40290 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7S4])

HSP 1 Score: 62.3882 bits (150), Expect = 3.586e-21
Identity = 24/30 (80.00%), Postives = 29/30 (96.67%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPECLLTDG+Y+++MDLWSVGCV FEI+
Sbjct:  165 YRAPECLLTDGFYTHKMDLWSVGCVFFEIM 194

HSP 2 Score: 58.5362 bits (140), Expect = 3.586e-21
Identity = 26/36 (72.22%), Postives = 30/36 (83.33%), Query Frame = -3 
Query:  608 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFK 715
            I SL PLFPG+NEVDQI KIHD+LG+P  SIL+ FK
Sbjct:  193 IMSLHPLFPGSNEVDQIAKIHDVLGTPVPSILQKFK 228

HSP 3 Score: 50.8322 bits (120), Expect = 6.264e-12
Identity = 18/29 (62.07%), Postives = 25/29 (86.21%), Query Frame = -3 
Query: 1877 DQSLKIADFGSCKTIFSRYPYTEYISTRW 1963
            D  +K+AD GSC++++S+ PYTEYISTRW
Sbjct:  136 DDIIKLADLGSCRSVYSKQPYTEYISTRW 164

HSP 4 Score: 38.5058 bits (88), Expect = 6.264e-12
Identity = 15/17 (88.24%), Postives = 17/17 (100.00%), Query Frame = -1 
Query: 2020 RNGIFHRDVKPENILIR 2070
            RNGIFHRDVKPENIL++
Sbjct:  119 RNGIFHRDVKPENILLK 135
[Close]
BLAST of SMED30006822 vs. Ensembl Nematostella
Match: EDO41147 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S560])

HSP 1 Score: 41.5874 bits (96), Expect = 2.091e-9
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D+W+VGC+M E+
Sbjct:  165 YRAPEVLLRSTNYSSPIDIWAVGCIMAEL 193

HSP 2 Score: 39.2762 bits (90), Expect = 2.091e-9
Identity = 15/27 (55.56%), Postives = 23/27 (85.19%), Query Frame = -3 
Query:  635 IFSLRPLFPGANEVDQIGKIHDILGSP 715
            +++LRPLFPG++EVD+I K+  +LG P
Sbjct:  193 LYTLRPLFPGSSEVDEIFKVCSVLGPP 219

HSP 3 Score: 40.817 bits (94), Expect = 3.737e-6
Identity = 20/46 (43.48%), Postives = 29/46 (63.04%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  +   SR PYT+Y+STRW      L +  ++Y +P+ I
Sbjct:  139 VKIADFGLARETRSRPPYTDYVSTRWYRAPEVL-LRSTNYSSPIDI 183

HSP 4 Score: 28.8758 bits (63), Expect = 3.737e-6
Identity = 10/15 (66.67%), Postives = 14/15 (93.33%), Query Frame = -1 
Query: 2026 RNGIFHRDVKPENIL 2070
            ++G FHRD+KPEN+L
Sbjct:  118 KHGYFHRDMKPENLL 132
[Close]
BLAST of SMED30006822 vs. Ensembl Nematostella
Match: EDO40841 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5Y1])

HSP 1 Score: 40.0466 bits (92), Expect = 6.530e-8
Identity = 17/33 (51.52%), Postives = 22/33 (66.67%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPE LL    YS  +D+WSVGC+  E+L  +
Sbjct:  316 YRAPELLLGIKEYSCPIDMWSVGCIFAELLTME 348

HSP 2 Score: 35.8094 bits (81), Expect = 6.530e-8
Identity = 17/37 (45.95%), Postives = 24/37 (64.86%), Query Frame = -3 
Query:  620 IFKTLIFSLRPLFPGANEVDQIGKIHDILGSPDASIL 730
            IF  L+ ++ PLFPG +E+DQI +I   LG+P   I 
Sbjct:  340 IFAELL-TMEPLFPGRSEIDQINRIFKELGTPSDKIW 375
[Close]
BLAST of SMED30006822 vs. Ensembl Nematostella
Match: EDO37435 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFQ0])

HSP 1 Score: 41.2022 bits (95), Expect = 2.057e-7
Identity = 16/30 (53.33%), Postives = 22/30 (73.33%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPE +L    YS  +D+WSVGC++ E+L
Sbjct:  189 YRAPEIMLNSKGYSKAIDIWSVGCILAEML 218

HSP 2 Score: 33.113 bits (74), Expect = 2.057e-7
Identity = 17/35 (48.57%), Postives = 23/35 (65.71%), Query Frame = -3 
Query:  608 RPLFPGANEVDQIGKIHDILGSP---DASILKNFK 703
            RPLFPG + +DQ+  I ++LGSP   D   +KN K
Sbjct:  221 RPLFPGKHYLDQLNLILNVLGSPIADDLLCIKNEK 255
[Close]
BLAST of SMED30006822 vs. Ensembl Nematostella
Match: EDO41403 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4F0])

HSP 1 Score: 40.4318 bits (93), Expect = 3.179e-7
Identity = 15/29 (51.72%), Postives = 21/29 (72.41%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL   YY+  +D+WS+GC+  E+
Sbjct:  168 YRAPEILLGSRYYATPVDVWSIGCIFAEM 196

HSP 2 Score: 33.113 bits (74), Expect = 3.179e-7
Identity = 13/27 (48.15%), Postives = 19/27 (70.37%), Query Frame = -3 
Query:  623 RPLFPGANEVDQIGKIHDILGSPDASI 703
            R LFPG +E+DQ+ +I   LG+PD  +
Sbjct:  200 RALFPGDSEIDQLFRIFRTLGTPDDKV 226
[Close]
BLAST of SMED30006822 vs. Ensembl Medaka
Match: MOK (MOK protein kinase [Source:NCBI gene;Acc:101173667])

HSP 1 Score: 60.8474 bits (146), Expect = 8.366e-21
Identity = 24/37 (64.86%), Postives = 33/37 (89.19%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL+PLFPGANE+DQ+ KIH++LG+PD S+L+ FK+
Sbjct:  254 IMSLKPLFPGANELDQVAKIHNVLGTPDQSLLQKFKQ 290

HSP 2 Score: 60.4622 bits (145), Expect = 8.366e-21
Identity = 23/33 (69.70%), Postives = 28/33 (84.85%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPECLLTDGYY+ +MD+WS GCV FEI+  +
Sbjct:  226 YRAPECLLTDGYYNLKMDIWSAGCVFFEIMSLK 258

HSP 3 Score: 50.447 bits (119), Expect = 1.890e-10
Identity = 18/26 (69.23%), Postives = 25/26 (96.15%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ADFGSC++++S+ P+TEYISTRW
Sbjct:  200 LKLADFGSCRSVYSKPPHTEYISTRW 225

HSP 4 Score: 35.8094 bits (81), Expect = 1.890e-10
Identity = 14/15 (93.33%), Postives = 15/15 (100.00%), Query Frame = -1 
Query: 2020 GIFHRDVKPENILIR 2064
            GIFHRDVKPENILI+
Sbjct:  182 GIFHRDVKPENILIK 196
[Close]
BLAST of SMED30006822 vs. Ensembl Medaka
Match: MOK (MOK protein kinase [Source:NCBI gene;Acc:101173667])

HSP 1 Score: 60.8474 bits (146), Expect = 1.002e-20
Identity = 24/37 (64.86%), Postives = 33/37 (89.19%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SL+PLFPGANE+DQ+ KIH++LG+PD S+L+ FK+
Sbjct:  248 IMSLKPLFPGANELDQVAKIHNVLGTPDQSLLQKFKQ 284

HSP 2 Score: 60.4622 bits (145), Expect = 1.002e-20
Identity = 23/33 (69.70%), Postives = 28/33 (84.85%), Query Frame = -1 
Query:  745 YRAPECLLTDGYYSYQMDLWSVGCVMFEILRFQ 843
            YRAPECLLTDGYY+ +MD+WS GCV FEI+  +
Sbjct:  220 YRAPECLLTDGYYNLKMDIWSAGCVFFEIMSLK 252

HSP 3 Score: 50.8322 bits (120), Expect = 1.801e-10
Identity = 18/26 (69.23%), Postives = 25/26 (96.15%), Query Frame = -3 
Query: 1877 LKIADFGSCKTIFSRYPYTEYISTRW 1954
            LK+ADFGSC++++S+ P+TEYISTRW
Sbjct:  194 LKLADFGSCRSVYSKPPHTEYISTRW 219

HSP 4 Score: 35.4242 bits (80), Expect = 1.801e-10
Identity = 14/15 (93.33%), Postives = 15/15 (100.00%), Query Frame = -1 
Query: 2020 GIFHRDVKPENILIR 2064
            GIFHRDVKPENILI+
Sbjct:  176 GIFHRDVKPENILIK 190
[Close]
BLAST of SMED30006822 vs. Ensembl Medaka
Match: ICK (ciliogenesis associated kinase 1 [Source:NCBI gene;Acc:101174616])

HSP 1 Score: 40.4318 bits (93), Expect = 1.849e-8
Identity = 16/29 (55.17%), Postives = 20/29 (68.97%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    YS  +D W+VGC+M E+
Sbjct:  165 YRAPEVLLRSTSYSSPIDQWAVGCIMAEL 193

HSP 2 Score: 38.891 bits (89), Expect = 1.849e-8
Identity = 16/27 (59.26%), Postives = 23/27 (85.19%), Query Frame = -3 
Query:  635 IFSLRPLFPGANEVDQIGKIHDILGSP 715
            +++LRPLFPG++EVD I KI  +LG+P
Sbjct:  193 LYTLRPLFPGSSEVDTIFKICQVLGTP 219

HSP 3 Score: 41.9726 bits (97), Expect = 2.147e-6
Identity = 21/44 (47.73%), Postives = 28/44 (63.64%), Query Frame = -3 
Query: 1823 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPV 1954
            +KIADFG  + I SR PYT+Y+STRW      L  + S Y +P+
Sbjct:  139 VKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTS-YSSPI 181

HSP 4 Score: 30.4166 bits (67), Expect = 2.147e-6
Identity = 11/27 (40.74%), Postives = 17/27 (62.96%), Query Frame = -1 
Query: 2026 FFYCFELFSLNSRNGIFHRDVKPENIL 2106
             F   +  +   ++G FHRD+KPEN+L
Sbjct:  106 MFQILQGLAFIHKHGFFHRDMKPENLL 132
[Close]
BLAST of SMED30006822 vs. Ensembl Medaka
Match: mak (male germ cell associated kinase [Source:NCBI gene;Acc:101162081])

HSP 1 Score: 42.3578 bits (98), Expect = 6.622e-8
Identity = 18/43 (41.86%), Postives = 26/43 (60.47%), Query Frame = -1 
Query:  757 KSKLSFKIKIYHKRYRAPECLLTDGYYSYQMDLWSVGCVMFEI 885
            +SK  +   +  + YRAPE LL    Y   +DLW+VGC+M E+
Sbjct:  153 RSKPPYTDYVSTRWYRAPEVLLRSSTYGSPIDLWAVGCIMAEL 195

HSP 2 Score: 35.4242 bits (80), Expect = 6.622e-8
Identity = 14/26 (53.85%), Postives = 22/26 (84.62%), Query Frame = -3 
Query:  638 IFSLRPLFPGANEVDQIGKIHDILGS 715
            +++LRPLFPG +E+D+I KI  +LG+
Sbjct:  195 LYTLRPLFPGNSEMDEIFKICQVLGT 220

HSP 3 Score: 43.8986 bits (102), Expect = 6.932e-7
Identity = 21/46 (45.65%), Postives = 30/46 (65.22%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  + I S+ PYT+Y+STRW      L +  S YG+P+ +
Sbjct:  141 VKIADFGLAREIRSKPPYTDYVSTRWYRAPEVL-LRSSTYGSPIDL 185

HSP 4 Score: 30.4166 bits (67), Expect = 6.932e-7
Identity = 13/40 (32.50%), Postives = 19/40 (47.50%), Query Frame = -1 
Query: 1987 FFYCFELFSLNSRNGIFHRDVKPENILIRVIIFFNYSRFG 2106
             F      +   ++G FHRD+KPEN+L         + FG
Sbjct:  108 LFQVLSGLAFVHKHGFFHRDMKPENLLCMGPELVKIADFG 147
[Close]
BLAST of SMED30006822 vs. Ensembl Medaka
Match: mak (male germ cell associated kinase [Source:NCBI gene;Acc:101162081])

HSP 1 Score: 42.3578 bits (98), Expect = 6.623e-8
Identity = 16/29 (55.17%), Postives = 20/29 (68.97%), Query Frame = -1 
Query:  757 YRAPECLLTDGYYSYQMDLWSVGCVMFEI 843
            YRAPE LL    Y   +DLW+VGC+M E+
Sbjct:  166 YRAPEVLLRSSTYGSPIDLWAVGCIMAEL 194

HSP 2 Score: 35.4242 bits (80), Expect = 6.623e-8
Identity = 14/26 (53.85%), Postives = 22/26 (84.62%), Query Frame = -3 
Query:  638 IFSLRPLFPGANEVDQIGKIHDILGS 715
            +++LRPLFPG +E+D+I KI  +LG+
Sbjct:  194 LYTLRPLFPGNSEMDEIFKICQVLGT 219

HSP 3 Score: 43.8986 bits (102), Expect = 2.996e-7
Identity = 21/46 (45.65%), Postives = 30/46 (65.22%), Query Frame = -3 
Query: 1817 LKIADFGSCKTIFSRYPYTEYISTRW*ELNRYLCVNLSHYGTPVGI 1954
            +KIADFG  + I S+ PYT+Y+STRW      L +  S YG+P+ +
Sbjct:  140 VKIADFGLAREIRSKPPYTDYVSTRWYRAPEVL-LRSSTYGSPIDL 184

HSP 4 Score: 31.5722 bits (70), Expect = 2.996e-7
Identity = 14/39 (35.90%), Postives = 20/39 (51.28%), Query Frame = -1 
Query: 1987 FYCFELFSLNSRNGIFHRDVKPENILIRVIIFFNYSRFG 2103
            F   +  S   ++G FHRD+KPEN+L         + FG
Sbjct:  108 FQILQGLSFIHKHGFFHRDMKPENLLCMGPELVKIADFG 146
[Close]
BLAST of SMED30006822 vs. Planmine SMEST
Match: SMESG000043386.1 (SMESG000043386.1)

HSP 1 Score: 77.0258 bits (188), Expect = 3.229e-29
Identity = 36/37 (97.30%), Postives = 36/37 (97.30%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            I SLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK
Sbjct:  196 ILSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 232

HSP 2 Score: 72.0182 bits (175), Expect = 3.229e-29
Identity = 30/30 (100.00%), Postives = 30/30 (100.00%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPECLLTDGYYSYQMDLWSVGCVMFEIL
Sbjct:  168 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 197

HSP 3 Score: 68.9366 bits (167), Expect = 2.750e-17
Identity = 29/29 (100.00%), Postives = 29/29 (100.00%), Query Frame = -3 
Query: 1877 DQSLKIADFGSCKTIFSRYPYTEYISTRW 1963
            DQSLKIADFGSCKTIFSRYPYTEYISTRW
Sbjct:  139 DQSLKIADFGSCKTIFSRYPYTEYISTRW 167

HSP 4 Score: 40.0466 bits (92), Expect = 2.750e-17
Identity = 16/17 (94.12%), Postives = 17/17 (100.00%), Query Frame = -1 
Query: 2020 RNGIFHRDVKPENILIR 2070
            +NGIFHRDVKPENILIR
Sbjct:  122 KNGIFHRDVKPENILIR 138
[Close]
BLAST of SMED30006822 vs. Planmine SMEST
Match: SMESG000075533.1 (SMESG000075533.1)

HSP 1 Score: 40.817 bits (94), Expect = 2.232e-8
Identity = 15/30 (50.00%), Postives = 24/30 (80.00%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPE +L+  +Y+ ++D+WSVGC+M E+ 
Sbjct:  209 YRAPEIMLSWMHYTNRVDIWSVGCIMAELF 238

HSP 2 Score: 38.1206 bits (87), Expect = 2.232e-8
Identity = 13/32 (40.62%), Postives = 23/32 (71.88%), Query Frame = -3 
Query:  620 IFSLRPLFPGANEVDQIGKIHDILGSPDASIL 715
            +F+ +PLFPG + +DQ+ KI ++ G+PD   +
Sbjct:  237 LFTRKPLFPGNDHIDQLKKIMELAGTPDKEFM 268
[Close]
BLAST of SMED30006822 vs. Planmine SMEST
Match: SMESG000075533.1 (SMESG000075533.1)

HSP 1 Score: 40.817 bits (94), Expect = 2.369e-8
Identity = 15/30 (50.00%), Postives = 24/30 (80.00%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPE +L+  +Y+ ++D+WSVGC+M E+ 
Sbjct:  185 YRAPEIMLSWMHYTNRVDIWSVGCIMAELF 214

HSP 2 Score: 37.7354 bits (86), Expect = 2.369e-8
Identity = 13/32 (40.62%), Postives = 23/32 (71.88%), Query Frame = -3 
Query:  620 IFSLRPLFPGANEVDQIGKIHDILGSPDASIL 715
            +F+ +PLFPG + +DQ+ KI ++ G+PD   +
Sbjct:  213 LFTRKPLFPGNDHIDQLKKIMELAGTPDKEFM 244
[Close]
BLAST of SMED30006822 vs. Planmine SMEST
Match: SMESG000012868.1 (SMESG000012868.1)

HSP 1 Score: 42.3578 bits (98), Expect = 7.600e-8
Identity = 16/30 (53.33%), Postives = 22/30 (73.33%), Query Frame = -1 
Query:  754 YRAPECLLTDGYYSYQMDLWSVGCVMFEIL 843
            YRAPE +L    YS  MD+WS+GC++ E+L
Sbjct:  190 YRAPEVMLNSKGYSKAMDMWSIGCILAEML 219

HSP 2 Score: 34.6538 bits (78), Expect = 7.600e-8
Identity = 14/28 (50.00%), Postives = 19/28 (67.86%), Query Frame = -3 
Query:  632 IFSLRPLFPGANEVDQIGKIHDILGSPD 715
            +   +PLFPG + V Q+  I D+LGSPD
Sbjct:  218 MLGCKPLFPGKHYVQQLKLIFDVLGSPD 245
[Close]
BLAST of SMED30006822 vs. Planmine SMEST
Match: SMESG000078149.1 (SMESG000078149.1)

HSP 1 Score: 42.3578 bits (98), Expect = 8.513e-8
Identity = 19/47 (40.43%), Postives = 28/47 (59.57%), Query Frame = -1 
Query:  757 FFLNKSKLSFKIKIYHKRYRAPECLLTDGYYSYQMDLWSVGCVMFEI 897
            F  + SK  +  K+    YRAPE LL +  Y   +D+WS+GC+M E+
Sbjct:  316 FEADNSKRPYTNKVITLWYRAPELLLGEEIYGEAIDVWSIGCIMGEL 362

HSP 2 Score: 34.2686 bits (77), Expect = 8.513e-8
Identity = 14/37 (37.84%), Postives = 22/37 (59.46%), Query Frame = -3 
Query:  605 IFSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK 715
            +F  R +F  +NE+DQ+  I  + G+P+A I  N  K
Sbjct:  362 LFVRRTMFTASNEMDQLETISKVCGTPNAGIWPNVTK 398
The following BLAST results are available for this feature:
BLAST of SMED30006822 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MOK3.840e-1958.70MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:98... [more]
MOK5.722e-1972.73MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:98... [more]
MOK5.817e-1972.73MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:98... [more]
MOK6.536e-1972.73MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:98... [more]
ICK3.842e-941.86intestinal cell kinase [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of SMED30006822 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dyf-51.915e-848.28Serine/threonine-protein kinase dyf-5 [Source:Uni... [more]
dyf-52.094e-837.21Serine/threonine-protein kinase dyf-5 [Source:Uni... [more]
cdk-11.12.587e-753.33Cyclin-dependent kinase 11.1 [Source:UniProtKB/Sw... [more]
cdk-11.12.652e-753.33Cyclin-dependent kinase 11.1 [Source:UniProtKB/Sw... [more]
pmk-17.711e-746.67Mitogen-activated protein kinase pmk-1 [Source:Un... [more]
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BLAST of SMED30006822 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG423665.780e-1038.30gene:FBgn0259712 transcript:FBtr0331633[more]
CG423665.928e-1038.30gene:FBgn0259712 transcript:FBtr0299965[more]
Pitslre5.596e-753.13gene:FBgn0016696 transcript:FBtr0304935[more]
Pitslre5.596e-753.13gene:FBgn0016696 transcript:FBtr0304936[more]
Pitslre5.596e-753.13gene:FBgn0016696 transcript:FBtr0331523[more]
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BLAST of SMED30006822 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mak2.084e-855.17male germ cell-associated kinase [Source:ZFIN;Acc:... [more]
mak2.170e-855.17male germ cell-associated kinase [Source:ZFIN;Acc:... [more]
cdk11b1.295e-746.15cyclin-dependent kinase 11B [Source:ZFIN;Acc:ZDB-G... [more]
cdk21.763e-753.33cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk63.518e-754.84cyclin-dependent kinase 6 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of SMED30006822 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ltb4r25.133e-2082.76leukotriene B4 receptor 2 [Source:Xenbase;Acc:XB-G... [more]
ltb4r26.254e-2082.76leukotriene B4 receptor 2 [Source:Xenbase;Acc:XB-G... [more]
ltb4r23.137e-1173.08leukotriene B4 receptor 2 [Source:Xenbase;Acc:XB-G... [more]
ICK9.251e-955.17intestinal cell (MAK-like) kinase [Source:NCBI gen... [more]
ICK1.112e-855.17intestinal cell (MAK-like) kinase [Source:NCBI gen... [more]
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BLAST of SMED30006822 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mok1.307e-1872.73MOK protein kinase [Source:MGI Symbol;Acc:MGI:1336... [more]
Mok4.577e-1169.23MOK protein kinase [Source:MGI Symbol;Acc:MGI:1336... [more]
Ick2.194e-955.17intestinal cell kinase [Source:MGI Symbol;Acc:MGI:... [more]
Ick2.445e-955.17intestinal cell kinase [Source:MGI Symbol;Acc:MGI:... [more]
Ick2.445e-955.17intestinal cell kinase [Source:MGI Symbol;Acc:MGI:... [more]
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BLAST of SMED30006822 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9UQ07|MOK_HUMAN2.572e-1872.73MAPK/MAK/MRK overlapping kinase OS=Homo sapiens OX... [more]
sp|Q9WVS4|MOK_MOUSE7.976e-1872.73MAPK/MAK/MRK overlapping kinase OS=Mus musculus OX... [more]
sp|O43077|MDE3_SCHPO3.079e-955.17Sporulation protein kinase mde3 OS=Schizosaccharom... [more]
sp|O14132|PIT1_SCHPO3.216e-954.55Sporulation protein kinase pit1 OS=Schizosaccharom... [more]
sp|P32581|IME2_YEAST5.962e-951.52Meiosis induction protein kinase IME2/SME1 OS=Sacc... [more]
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BLAST of SMED30006822 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
W4Z7371.515e-2072.09Protein kinase domain-containing protein OS=Strong... [more]
A0A210QFC87.294e-2078.79MAPK/MAK/MRK overlapping kinase OS=Mizuhopecten ye... [more]
H2YWW91.150e-1960.87Protein kinase domain-containing protein OS=Ciona ... [more]
A0A3Q0JV151.748e-1983.33MAPK/MAK/MRK overlapping kinase OS=Ciona intestina... [more]
K1QVT72.617e-1986.67MAPK/MAK/MRK overlapping kinase OS=Crassostrea gig... [more]
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BLAST of SMED30006822 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MOK2.641e-2080.00MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:98... [more]
ICK8.814e-955.17serine/threonine-protein kinase ICK-like [Source:N... [more]
ICK1.004e-855.17serine/threonine-protein kinase ICK-like [Source:N... [more]
mak1.260e-855.17male germ cell associated kinase [Source:NCBI gene... [more]
mak1.270e-855.17male germ cell associated kinase [Source:NCBI gene... [more]
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BLAST of SMED30006822 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mak2.423e-962.96male germ cell-associated kinase [Source:ZFIN;Acc:... [more]
mapk11.579e-750.00mitogen-activated protein kinase 1 [Source:ZFIN;Ac... [more]
cdk22.134e-753.33cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk44.952e-754.84cyclin-dependent kinase 4 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk11.913e-650.00cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of SMED30006822 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
IME21.066e-1051.52Serine/threonine protein kinase involved in activa... [more]
SMK18.235e-753.57Middle sporulation-specific mitogen-activated prot... [more]
SSN31.173e-651.52Cyclin-dependent protein kinase; component of RNA ... [more]
CDC281.342e-651.72Cyclin-dependent kinase (CDK) catalytic subunit; m... [more]
RIM111.890e-653.33Protein kinase; required for signal transduction d... [more]
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BLAST of SMED30006822 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO402903.586e-2180.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO411472.091e-955.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO408416.530e-851.52Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO374352.057e-753.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO414033.179e-751.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SMED30006822 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MOK8.366e-2164.86MOK protein kinase [Source:NCBI gene;Acc:101173667... [more]
MOK1.002e-2064.86MOK protein kinase [Source:NCBI gene;Acc:101173667... [more]
ICK1.849e-855.17ciliogenesis associated kinase 1 [Source:NCBI gene... [more]
mak6.622e-841.86male germ cell associated kinase [Source:NCBI gene... [more]
mak6.623e-855.17male germ cell associated kinase [Source:NCBI gene... [more]
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BLAST of SMED30006822 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000043386.13.229e-2997.30SMESG000043386.1[more]
SMESG000075533.12.232e-850.00SMESG000075533.1[more]
SMESG000075533.12.369e-850.00SMESG000075533.1[more]
SMESG000012868.17.600e-853.33SMESG000012868.1[more]
SMESG000078149.18.513e-840.43SMESG000078149.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006822 ID=SMED30006822|Name=SMED30006822|organism=Schmidtea mediterranea sexual|type=transcript|length=2997bp
TTCTTAATTTTTTGATTATTTACATTTTGCAACGCTCACAGTCATATTTC
AGATTTTAATCTTCCTGATCACTGAGCACATCAGCATACTAAATGACAAC
ATTGGTTTAATAAAAATTTAGTATTATCATGATAATGTTTTAGAGGGATA
CAGAGCTTTGTAATTTAATATTTGATGGGGGTTAATTCTTTGTGACGAAT
TGTGATGAAGGGGAGTGTCATTCATATTGCTTTAGTTTTGGCATTAATTC
AACTTATAATCACATTTTTACGAATGAAAACTTTGATGTCTGTTATAATT
ATCGAACTTCGTCATTTTGCAGCTATTCTTCTGAAGTGCCTACCGTGTTC
CCACGGTTATCCTTCCGTTTCTGCTGCAATGTCTCCCTCATTCAACAACG
ATGTATTCGTAAAAAAACGTCAACTGCTTTCGTCTCATCGGCAATTTCAA
CAAGCTTACAATGGTATAGCACAAATAAGTAACGGGGAACGTCTTAGAAA
AGTTAGTATATTTAAAATAAAAATCAAATGGCAAGCGAGACAGCAGAGGC
AACCGACTGTCATAAGTTCACAATTATTAGTATAAATATATATTGACAAA
TTTACTTTTTAAAATTTTTTAAAATGCTTGCATCAGGACTGCCCAATATG
TCGTGAATCTTTCCGATTTGATCTACTTCATTAGCACCGGGAAATAATGG
CCGAAGGCTAAAAATCAGAGTTTTAAATATAAAATTTTTTGCCACTGGAA
CCTTAGAATCTCGAACATTACACACCCAACACTCCAAAGATCCATTTGGT
AGCTGTAATAGCCATCGGTTAATAGACATTCAGGAGCCCGATACCTTTTA
TGATAAATTTTAATTTTAAAACTTAATTTTGATTTATTCAAAAAAAACAG
TTTGGTCCTTTTAAGCATCGTTTTTTATAAAGAGGAAGTTTAGGAAGTTT
TTTAGAAACCAATGCCCTAGGACGTTTAAAAGATTTGTAGCTTACATAAT
AAGTAGTTCAAGGAGTACACTTAGTACAGAGACCATGAGGTTGCGCCAAC
ATTCCCTCTAGTCTGTTTAAGAGAAAATGTGAAGATAGCATTGCCCTAGT
CTAAAGTCCTTACAAATCATTATAAAACCTCCGGAAATATGGAAAATAAT
TTATTTGAATGCATCTATGCGTCAAAAGATAGAAGAATTCAGTTTTGGTT
TTGAAGCCAGTGTCGTTTGAGGTTAAATACAATACTCCTGACAGCAGGAG
CCAAACTTCCTATGTGTCAACTGTATCCTAACAATATGAAGACAGTTAAT
AACGCAACCGTTAAACATTGTAAAATTTAATAAATAATTAATTTCTGCTT
AGTTATTTGATGTTTTAATTTTTTTTGGCTGTTTCAGTCAAAAACTCAAG
TTTGTGTGTATATGTGTGTGAATGATAAAATTGCACACATGCTTGTATGC
GTGTATACGTTATATACACGAGCTTTCATAAATTACCATCAGAAATGATT
GACAGTTCTATCGACAAGTTATATATTGATCAGCAACCGACTCACTTAAA
TAAGTCAAAATAACATTCCAACTCACTGCGGATTGCTTTGGACGGGTATT
CTATGCGTGCATGTTAATTAATTACCAGCAAAAGTGGTTAAATTAAATTT
ATTTTTTCACTTAATTATTTTATTTATTTATTTTTCAAAAGATTATATCG
ATACTTCTTTTTGGCACGCCCTTCATTTATTGATATAATTTATAATTTTA
ATTAATAATTAATTGTGATTAGGTGTCATGTCAACCGAGTAAAACCGAGT
TAGGTCAAGTGAAAGATATTCCGACAGGGGTGCCATAGTGAGATAAATTT
ACACATAAATAGCGATTTAATTCTTACCATCTTGTGGATATATATTCTGT
ATACGGATACCGGGAAAATATAGTTTTACACGATCCAAAATCTGCAATTT
TCAACGATTGATCCTAAAAATGTATGAAAAATAATTACCAAACCTAGAAT
AATTGAAGAAAATAATTACTCTTATTAAAATATTTTCAGGTTTAACATCT
CTGTGAAAAATGCCATTTCTAGAATTTAAAGAAAATAATTCGAAACAATA
AAAAAAGTTTTGCGGGAAAATTACAATAATTTTTATTCCCAAAATCAACA
GTTAGCCACGAAATTTAATAAAAATAATAATAAATTTAATTTTAATTAAT
TCTATTTTTAACTAGCCAAGATGAGGGGTTCCCATTGTTCTTGATAACTC
ACACGTTTGACTATCTTCGCAAATGACAGTTGGAGGCTGAGGACCAGTAG
CTAGCAAGCATGGTCAATTTTTATGGGCCACAGGTTGCCAACCCCTAGCT
TAGACGTTAAACTATTGACATAAAAATATTATGAAACCGATCATTTAATA
TAAGGATTTTGCCACAAGCGGCGTGAATTTCCACCCGACTCATTGTGGAA
GAATGCAATACAGTTGACCTATTTGTGTATCAAAGTATATAAACATAAAA
GTTACAGTAATAACATGTTTATCAGATATACGATTGATAAAGTCGCAGCC
AGAATTTGTTAATGGGGGTTAAGGTTTAGGACTTTGTACCATGGGTGAAT
ATATTCCGACAAACATTTTATGCGGTTAATTTTGGGTTTCAAGGAAACCT
TTACCATAAAAAGTTGCTCGGACATTATCATTATTATTGCGCAGAAAGAG
TTACATTCTATAAAATTGACCAAAGAGAACCTTTGCAGGGATTCCAAAGT
TTGATTTTAAGTTAGTTTCTTTACCAATTTTTTGTTTTCTTTATTTTCAT
CGTCAAGCTATGTATTCACCGGGGGAGATAGAATTCCACACGCCACCACC
AAACCTGCGCCTCTGCGTACTTCTATATCTGGACGCATCAGAGTCCGCGG
GTAAAGGACTAGGAAGAGTTACTGAACATTTTAATTTAGTAAATGTATTA
TTATAGTATAGGACCAGAGCTTCTTAAAGTTTTGTAATTCACAGATC
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protein sequence of SMED30006822-orf-1

>SMED30006822-orf-1 ID=SMED30006822-orf-1|Name=SMED30006822-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=127bp
MKGSVIHIALVLALIQLIITFLRMKTLMSVIIIELRHFAAILLKCLPCSH
GYPSVSAAMSPSFNNDVFVKKRQLLSSHRQFQQAYNGIAQISNGERLRKV
SIFKIKIKWQARQQRQPTVISSQLLV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom_sf
IPR019774Aromatic-AA_hydroxylase_C
IPR008271Ser/Thr_kinase_AS
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0016714oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0055114oxidation-reduction process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableTMHMMTMhelixcoord: 5..22