cilia- and flagella-associated protein 57

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSM--RKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEF--------NLAASL-ILEEAQKL------------------ENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRK-------QGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKI 3618
            M+   A   HVFG R  V   I Y +EQ +++P G++ V YN+DQ+ QKFI G EKS  M A++ISPNRRY+A++ET  E KP I IY+L+S+  RK+K L+  +    +F S++FSPDSKYL  QTS P+  L+YW WEK K +A  R+ +   N  V Q+SF+PQD+TQ+C  GN  FK+ R++E  LK     + E QN+L HTWV+D+++++GTDTGKL L E+G+ R E         N + SL +++E++ L                   ++   ++  QV  I + SKGFA + G G+V  FEK ++K++Y++ REI IPVD  S DP +S  Q +  +C SPSEET+VA T+ +QLYS T+S TEI+K G+ ++FE L Y  H + I GL  C RKP+IATC++DRS+R+WNYETN LEL+KE+ EEAYSI+LHPSG +I+VGF+DKLRLMN+LIDDIR+FKE+S+RGC EC+FS GGH FAAV+ N+I +Y+TT+ E + SLKGH GKIR++VW  DD KLIS G DGAVYEW+ +TGKR  E VLKSCSY  ++V+ D K  +AVG+D TLKEI+DS +LRE+ + DV  T + +S+SGRM+F GT+ G+IR+ K+PL    E+ EY  H+  ITKM +T +D +L+T ++D  +  W+V DK+GR +KR++++G+AEE+L+TK+D+EEK   M EL+TRV+ELKMENEYQLRLKDMNY+EKIKELT+KFIQEMESLKTKNQVL+TEK+K++  H E + ++++K S+ELQD+E  NNQKL+LEYEKYQELQ KSQRMQE+YE+QL++ +  K QALEELTE+YE K  EK+T+LE   +D+R Q  E+EETK+ IEED DREI D K KYE++LR+E+ESN RLKGETGIM+KKF+SLQKEI+++  +I+  + E  KL+ VI++LEKD  GLK+EIQERDETIQDKEKRIYDLKKKNQEL KFKFVLDYKIKELKKQIEPRE EI+  KEQIQEME+ELE FHKQN QL LNI EL QKL++T++E++ ERQ  RD+EA V+RFKTDL+NCV+YIQ+P+ LKE +  L++K++Q            A ++ D+Q+E+TRQREHLER++A+L+KK+ K+ E+HR DYVRIMQENVSLIKEIN+LR+ELK +R+  +DLEAAL L +K       + E +R +++     +       E EE GR++EMQR  I +LRD+I
Sbjct:    1 MSAVVAQTLHVFGLRSHVANNIFYFDEQIIIFPSGNHCVKYNVDQKWQKFIPGSEKSQGMLALSISPNRRYLAISETVQE-KPAITIYELSSIPCRKRKVLNNFDFQVQKFISMAFSPDSKYLLAQTSPPESNLVYWLWEKQKVMAIVRIDT--QNNPVYQVSFSPQDNTQVCVTGNGMFKLLRFAEGTLKQTSFQRGEPQNYLAHTWVADDKIVVGTDTGKLFLFESGDQRWETSIMVKEPTNGSKSLDVIQESESLIEFPPVSSPLPSYEQMVAASSHSQMSMPQVFAIAAYSKGFACSAGPGRVLLFEKMEEKDFYRESREIRIPVDPQSNDPSQSDKQDVLCLCFSPSEETLVASTSKNQLYSITMSLTEISK-GEPAHFEYLMYPLHSAPITGLATCIRKPLIATCSLDRSIRLWNYETNTLELFKEYQEEAYSISLHPSGHFIVVGFADKLRLMNLLIDDIRSFKEYSVRGCGECSFSNGGHLFAAVNGNVIHVYTTTSLENISSLKGHTGKIRSIVWNADDSKLISGGTDGAVYEWNLSTGKRETECVLKSCSYNCVTVSPDAKIIFAVGSDHTLKEIADSLILREISAFDVTYTAIVISHSGRMMFVGTSVGTIRAMKYPLPLQKEFNEYQAHAGPITKMLLTFDDQFLLTAAEDGCLFTWKVFDKDGRGIKREREVGFAEEVLVTKTDMEEKAQVMLELKTRVEELKMENEYQLRLKDMNYSEKIKELTDKFIQEMESLKTKNQVLRTEKEKQDVYHHEHIEDLLDKQSRELQDMECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTTLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYEKKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIETLKGEQMKLQGVIKSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELGKFKFVLDYKIKELKKQIEPRENEIRVMKEQIQEMEAELENFHKQNTQLELNITELWQKLRATDQEMRRERQKERDLEALVKRFKTDLHNCVAYIQEPRLLKEKVRGLFEKYVQR-----ADMVEIAGLNTDLQQEYTRQREHLERNLATLKKKVVKEGELHRTDYVRIMQENVSLIKEINELRRELKFTRSQVYDLEAALKLTKKVRPQEVSETEPSRDMLSTAPTARL-----NEQEETGRIIEMQRLEIQRLRDQI 1218          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSM--RKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEF--------NLAASL-ILEEAQKL------------------ENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQE---------------------------------MESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRK-------QGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKI 3618
            M+   A   HVFG R  V   I Y +EQ +++P G++ V YN+DQ+ QKFI G EKS  M A++ISPNRRY+A++ET  E KP I IY+L+S+  RK+K L+  +    +F S++FSPDSKYL  QTS P+  L+YW WEK K +A  R+ +   N  V Q+SF+PQD+TQ+C  GN  FK+ R++E  LK     + E QN+L HTWV+D+++++GTDTGKL L E+G+ R E         N + SL +++E++ L                   ++   ++  QV  I + SKGFA + G G+V  FEK ++K++Y++ REI IPVD  S DP +S  Q +  +C SPSEET+VA T+ +QLYS T+S TEI+K G+ ++FE L Y  H + I GL  C RKP+IATC++DRS+R+WNYETN LEL+KE+ EEAYSI+LHPSG +I+VGF+DKLRLMN+LIDDIR+FKE+S+RGC EC+FS GGH FAAV+ N+I +Y+TT+ E + SLKGH GKIR++VW  DD KLIS G DGAVYEW+ +TGKR  E VLKSCSY  ++V+ D K  +AVG+D TLKEI+DS +LRE+ + DV  T + +S+SGRM+F GT+ G+IR+ K+PL    E+ EY  H+  ITKM +T +D +L+T ++D  +  W+V DK+GR +KR++++G+AEE+L+TK+D+EEK   M EL+TRV+ELKMENEYQLRLKDMNY+EKIKELT+KFIQEMESLKTKNQVL+TEK+K++  H E + ++++K S+ELQD+E  NNQKL+LEYEKYQELQ KSQRMQE+YE+QL++ +  K QALEELTE+YE K  EK+T+LE   +D+R Q  E+EETK+ IEED DREI D K KYE++LR+E+ESN RLKGETGIM+KKF+SLQKEI+++  +I+  + E  KL+ VI++LEKD  GLK+EIQERDETIQDKEKRIYDLKKKNQEL KFKFVLDYKIKELKKQIEPRE EI+  KEQIQE                                 ME+ELE FHKQN QL LNI EL QKL++T++E++ ERQ  RD+EA V+RFKTDL+NCV+YIQ+P+ LKE +  L++K++Q            A ++ D+Q+E+TRQREHLER++A+L+KK+ K+ E+HR DYVRIMQENVSLIKEIN+LR+ELK +R+  +DLEAAL L +K       + E +R +++     +       E EE GR++EMQR  I +LRD+I
Sbjct:    1 MSAVVAQTLHVFGLRSHVANNIFYFDEQIIIFPSGNHCVKYNVDQKWQKFIPGSEKSQGMLALSISPNRRYLAISETVQE-KPAITIYELSSIPCRKRKVLNNFDFQVQKFISMAFSPDSKYLLAQTSPPESNLVYWLWEKQKVMAIVRIDT--QNNPVYQVSFSPQDNTQVCVTGNGMFKLLRFAEGTLKQTSFQRGEPQNYLAHTWVADDKIVVGTDTGKLFLFESGDQRWETSIMVKEPTNGSKSLDVIQESESLIEFPPVSSPLPSYEQMVAASSHSQMSMPQVFAIAAYSKGFACSAGPGRVLLFEKMEEKDFYRESREIRIPVDPQSNDPSQSDKQDVLCLCFSPSEETLVASTSKNQLYSITMSLTEISK-GEPAHFEYLMYPLHSAPITGLATCIRKPLIATCSLDRSIRLWNYETNTLELFKEYQEEAYSISLHPSGHFIVVGFADKLRLMNLLIDDIRSFKEYSVRGCGECSFSNGGHLFAAVNGNVIHVYTTTSLENISSLKGHTGKIRSIVWNADDSKLISGGTDGAVYEWNLSTGKRETECVLKSCSYNCVTVSPDAKIIFAVGSDHTLKEIADSLILREISAFDVTYTAIVISHSGRMMFVGTSVGTIRAMKYPLPLQKEFNEYQAHAGPITKMLLTFDDQFLLTAAEDGCLFTWKVFDKDGRGIKREREVGFAEEVLVTKTDMEEKAQVMLELKTRVEELKMENEYQLRLKDMNYSEKIKELTDKFIQEMESLKTKNQVLRTEKEKQDVYHHEHIEDLLDKQSRELQDMECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTTLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYEKKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIETLKGEQMKLQGVIKSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELGKFKFVLDYKIKELKKQIEPRENEIRVMKEQIQENDPILKWPQRVEIHLYNFRKQVRKVLLWGTLPQMEAELENFHKQNTQLELNITELWQKLRATDQEMRRERQKERDLEALVKRFKTDLHNCVAYIQEPRLLKEKVRGLFEKYVQR-----ADMVEIAGLNTDLQQEYTRQREHLERNLATLKKKVVKEGELHRTDYVRIMQENVSLIKEINELRRELKFTRSQVYDLEAALKLTKKVRPQEVSETEPSRDMLSTAPTARL-----NEQEETGRIIEMQRLEIQRLRDQI 1251          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSM--RKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNL--------AASL-ILEEAQKL------------------ENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKM 1887
            M+   A   HVFG R  V   I Y +EQ +++P G++ V YN+DQ+ QKFI G EKS  M A++ISPNRRY+A++ET  E KP I IY+L+S+  RK+K L+  +    +F S++FSPDSKYL  QTS P+  L+YW WEK K +A  R+ +   N  V Q+SF+PQD+TQ+C  GN  FK+ R++E  LK     + E QN+L HTWV+D+++++GTDTGKL L E+G+ R E ++        + SL +++E++ L                   ++   ++  QV  I + SKGFA + G G+V  FEK ++K++Y++ REI IPVD  S DP +S  Q +  +C SPSEET+VA T+ +QLYS T+S TEI+K G+ ++FE L Y  H + I GL  C RKP+IATC++DRS+R+WNYETN LEL+KE+ EEAYSI+LHPSG +I+VGF+DKLRLMN+LIDDIR+FKE+S+RGC EC+FS GGH FAAV+ N+I +Y+TT+ E + SLKGH GKIR++VW  DD KLIS G DGAVYEW+ +TGKR  E VLKSCSY  ++V+ D K  +AVG+D TLKEI+DS +LRE+ + DV  T + +S+SGRM+F GT+ G+IR+ K+PL    E+ EY  H+  ITK+
Sbjct:    1 MSAVVAQTLHVFGLRSHVANNIFYFDEQIIIFPSGNHCVKYNVDQKWQKFIPGSEKSQGMLALSISPNRRYLAISETVQE-KPAITIYELSSIPCRKRKVLNNFDFQVQKFISMAFSPDSKYLLAQTSPPESNLVYWLWEKQKVMAIVRIDT--QNNPVYQVSFSPQDNTQVCVTGNGMFKLLRFAEGTLKQTSFQRGEPQNYLAHTWVADDKIVVGTDTGKLFLFESGDQRWETSIMVKEPTNGSKSLDVIQESESLIEFPPVSSPLPSYEQMVAASSHSQMSMPQVFAIAAYSKGFACSAGPGRVLLFEKMEEKDFYRESREIRIPVDPQSNDPSQSDKQDVLCLCFSPSEETLVASTSKNQLYSITMSLTEISK-GEPAHFEYLMYPLHSAPITGLATCIRKPLIATCSLDRSIRLWNYETNTLELFKEYQEEAYSISLHPSGHFIVVGFADKLRLMNLLIDDIRSFKEYSVRGCGECSFSNGGHLFAAVNGNVIHVYTTTSLENISSLKGHTGKIRSIVWNADDSKLISGGTDGAVYEWNLSTGKRETECVLKSCSYNCVTVSPDAKIIFAVGSDHTLKEIADSLILREISAFDVTYTAIVISHSGRMMFVGTSVGTIRAMKYPLPLQKEFNEYQAHAGPITKV 644          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSM--RKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDS 531
            M+   A   HVFG R  V   I Y +EQ +++P G++ V YN+DQ+ QKFI G EKS  M A++ISPNRRY+A++ET  E KP I IY+L+S+  RK+K L+  +    +F S++FSPDSKYL  QTS P+  L+YW WEK K +A  R+ +   N  V Q+SF+PQD+
Sbjct:    1 MSAVVAQTLHVFGLRSHVANNIFYFDEQIIIFPSGNHCVKYNVDQKWQKFIPGSEKSQGMLALSISPNRRYLAISETVQE-KPAITIYELSSIPCRKRKVLNNFDFQVQKFISMAFSPDSKYLLAQTSPPESNLVYWLWEKQKVMAIVRIDT--QNNPVYQVSFSPQDN 166          

Query: 1987 DKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQV 2205
            ++++G+AEE+L+TK+D+EEK   M EL+TRV+ELKMENEYQLRLKDMNY+EKIKELT+KFIQEMESLKTKNQV
Sbjct:    2 EREVGFAEEVLVTKTDMEEKAQVMLELKTRVEELKMENEYQLRLKDMNYSEKIKELTDKFIQEMESLKTKNQV 74          

Query: 1474 SLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYT-GISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVD--VQLTTVTLSNSGRMLFCGTNNGSIRSF-------KFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQ 1959
            ++KGH+G + ++ +TTD   L+SCG D +V  WD  TG  C         +   +  ++ G    A  +D     + D +    V++     Q T VT ++S   +  G  +  ++ +        + LT         GH   IT + ++P+  ++++ S DC V  W ++
Sbjct:   76 TIKGHSGAVMDLKFTTDSSSLVSCGTDKSVRVWDMETGT-CARRFRTHTDFVNAVHPSRRGVTLVASASDDGTCRVHDMRTKEPVKTYTNRYQQTAVTFNDSSDQVISGGIDNVLKVWDMRRDEITYTLT---------GHRDTITGISLSPSGKFIISNSMDCTVRQWDIR 237          

Query: 1165 IATCAVDRSVRIWNY-ETNQLELYKEFAEEAYSIALHPSGLYILVG-FSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHY-FAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDS--QVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKF 1824
            + +C+ D +V +W+  + + +   ++  +    +A HP+G ++    F    R+ ++       ++E   +   + AF   G       H    +++       +M L GH  +I +V W  +  ++I+   D ++  WD    +        +   T +     G+   +   D TLK  S +  Q LR+++  D ++  V +S  G+ +    ++   R+FK 
Sbjct:  269 VVSCSYDGTVLLWSLSQESPIGELEQHPQRVSKVAFHPNGHHLATACFDSTWRMYDLTTKKELLYQEGHSKSVADVAFHPDGSVALTGGHDCYGRVWDMRTGRCIMFLDGHTKEIHSVEWMPNGYEMITGSSDNSMKVWDLRMRRNTYTMPAHTSVVTRVRADAAGQYLVSASFDCTLKMWSTTGWQPLRQLQGHDTRILCVDISPDGQWM---CSSAFDRTFKL 490          

Query: 1456 NFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESV-----DVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQ 1959
            NF V   LKGH G I  V +  D   L+S G D  V  WD  TG         +     + V + G       +D     + D   +R  E+        Q T VT +++   + CG  +  I+ +   + +        GH   IT + ++ N ++L++ S DC +M W ++
Sbjct:   71 NFAV---LKGHKGAIMEVKFNADSSHLVSAGTDKTVRVWDMETGSCIRNFKSHTDIVNSVDVNRRGPQMICSASDDGTVMVHD---MRSKEAAKKFICKYQQTAVTFNDAADNVICGGIDNQIKVWD--MLRNDVRYVLSGHRDTITSLSVSHNGNFLLSNSMDCSLMSWDIR 235          

Query: 1117 HYSQILGLDLCRRKPIIATCAVDRSVRIWN-YETNQLELYKEFAEEAYSIALHPSGLYILVG-FSDKLRLMNILI-DDI-----RTFKEFSIRGCKECAFSYGGHY-FAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDD--KKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREV-----ESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIW 1950
            H  ++L +D    K  I + + D  V +W+ + TN+            + A  PS   I  G   +K  ++ +   DDI     +     S   C  C F    +        +   I+   + +++ +  GH G +  +     D     IS G D     WD  +G+ C +S     +           + +A G+D     + D +  R+V     ES+   +  V  S SGR+LF G   G  R   +   K        GH  +I+ ++ +P+   + + S DC + IW
Sbjct:   80 HVGKVLCMDWSLDKRHIVSSSQDGKVIVWDGFTTNKEHALTMPTTWVMACAFSPSSQMIACGGLDNKCSVVPLSFEDDIIQKKRQVATHTSYMSC--CTFLRSDNLILTGSGDSTCAIWDVESGQLIQNFHGHTGDVFAIDVPKCDTGNTFISAGADKHSLVWDIRSGQ-CVQSFEGHEADINTVRFHPNGDAFATGSDDATCRLFDLRADRQVCVYEKESILFPVNGVDFSLSGRILFAGY--GDYRVGVWDSLKCARHSVLYGHENRISCLRTSPDGTAVCSASWDCTIRIW 368          

Query:   61 VFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILAN-EFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIR-----TEFNLAASLILEEA---------QKLENNQGV-LNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISV-TQDGKNTYAVGTDKTLKEISDSQVLREV---ESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPG--EWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDL 3411
            ++G R  V G I +   + ++YP    L  ++  Q  Q+F+  L +  +   ++IS +R+ +A+ E  S++   I IY+L +++K++ L  P    N E   + F+ DS+ +A  T  P+  LI    +K+  +   R T P ++     I+ NP D   +   G     +   SE        LKV+ +      ++S + +++GT   +LILVENGE +     ++ +    +I +E          Q+    Q V L + +V  + +  KGFA      +   FE+      +K  R+ ++ V +N     +   QI+N + I   +ET++  T+  Q+Y   L   E  K      FE L    H  +I+ + +C  KPII T + D+++RIWNYET  +EL ++F  +   + L  +G    +GFSD+LR+  I +DD+   K ++   C    +S  GH  AA + N I I S    +V+++LKGHNG + +V W+  DK LIS G +GA+Y WD  TG R  E V K   Y  IS  T D    YA  +  T++E  DS ++RE+         ++ V L+ S  ++F   + G++ + + P  + G   +  +      + K++ + +   L  IS+   + IW + + EG+    D+D+  ++E+LI +S L +K   +A L  R+ +   E +YQL   ++   ++++E+   +   +E LK  N  ++    +E      +++ + E+H  +L  + +  ++++++EY+K+  L+     ++E YE +L+      +  +E L   Y+ +  E+  ++ +L K+M+D+  E+ E  R +E + DR ++ T+ +YE +L  ER      +G+ G+++KKF S  +EID+  EE++  + E  K +  I+   ++   L+K+I +RD  I  KEKRI DL  KNQELDK+K VL +KI ELK QIEPRE +I   ++ I EME+ELE  ++ N QL L + E++ K  S   EL+TER   +     +    +D+Y     I   + LK+++  L++KH  +D     +     ++DA+++ EF RQR  +E +V    K +++D  + +  Y ++ +ENV LI+EI  L
Sbjct:   26 IYGLRSDVIGNIHFNLTKEVIYPVEGVLAFHDYVQNKQRFLR-LPEDTRPEVISISSHRKLLAVVERHSKNGRYISIYELATLKKRRHLELPSNHRNAEIQQMIFTNDSRSVALITRPPEETLIMLVLDKTSTVIEGRATIPGSHGGAECIAGNPNDCNFMAVGGERTLLLMSKSERGFSISNNLKVKYR-VTSMAFLSLDLLMIGTSDDQLILVENGEQKLAQKASDADTVDLMIDQEVFDRDKELQEQRFLPTQAVSLPDRRVLCMTAFPKGFAYII-FNRAFVFERVSK---FKFERKTILTVPTNLY--AEHMYQILN-LAIDHKQETVIVTTSHCQIYVGILIVPETLKT-KQLKFEPLGVLIHTGEIIAMSVCAWKPIIMTASRDQTIRIWNYETALVELVRKFQVDVNIVELSLTGQMAAIGFSDQLRITQIFMDDLNIVKTYNFPHCNAVRYSNFGHMMAAAYDNNIAITSVYKLDVLINLKGHNGIVLSVAWSRTDKFLISGGAEGAIYLWDIETGARLQEIVQKGTEYVTISCSTNDPLTIYAGTSIGTIREFQDSTLMREITIPSRTKGSVSDVCLARSDLIMFVADHEGNLFNMQLPFLEAGGGTFTNFRFFDGPVNKLRFSYDGTLLFAISNKGTLAIWAMDNIEGKVPYMDQDLMRSQEVLIPRSQLNDKIEQIANLELRLKQQAEEFQYQLSQNEIFDGQQLQEVHRSYCSALEELKELNNEIEARHTEEMNHITFQINSIREEHRIQLDTLATQYSERMLIEYQKFTNLRENMLELRESYEDKLKNSTGTLQDTVEALENNYKQQLNERKELIRDLMKEMQDKKAEFIEYCREVELENDRNMVSTQTEYENKLTTERNETQMWRGKAGVLQKKFESQSREIDNLLEEVEILKEEHHKSQRNIQKQMRNIEDLQKDIADRDYAINGKEKRIQDLLHKNQELDKYKQVLGHKIAELKAQIEPREFQINDKRKHIIEMEAELEGLNQNNVQLELQLKEMRDKYLSNVAELRTERHRAKASRECLHSICSDIYYVAGEINSAEALKKAVKELFRKHASDD-----ELKRFVTLDAEVRDEFMRQRRQIE-NVLDRYKSVAEDKSVQKK-YDKLFKENVILIEEIEKL 1147          

Query: 1462 EVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVD--VQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQ 1959
            E VM++ GH+G +    +T D   + +C  D  +  WD  TG+R             +  ++ G+     G+D    +I D++      +++   Q+T V   ++G  +  G  +  ++ +   + K        GHS  IT M ++P  D+++T + D  + +W V+
Sbjct:   89 ENVMAMSGHSGAVMEAHFTPDGSHIFTCSTDKTLAFWDIATGQRQRRFKGHGNFVNSVQGSRRGQQLLCSGSDDRTIKIWDARKKHAAHTLESPFQVTAVCFGDTGEQVISGGIDNEVKIWD--IRKQAVLHHLRGHSDTITGMSLSPEGDFILTNAMDNTLRVWDVR 254          

Query: 1462 EVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVD--VQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQ 1959
            E VM++ GH+G +    +T D   + +C  D  +  WD  TG+R             +  ++ G+     G+D    +I D++      +++   Q+T V   ++G  +  G  +  ++ +   + K        GHS  IT M ++P  D+++T + D  + +W V+
Sbjct:   89 ENVMAMSGHSGAVMEAHFTPDGSHIFTCSTDKTLAFWDIATGQRQRRFKGHGNFVNSVQGSRRGQQLLCSGSDDRTIKIWDARKKHAAHTLESPFQVTAVCFGDTGEQVISGGIDNEVKIWD--IRKQAVLHHLRGHSDTITGMSLSPEGDFILTNAMDNTLRVWDVR 254          

Query: 1462 EVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGK-----RCGESVLKSCSYTGISVTQDGKNTYAVGTDK--TLKEISDSQVLREV-ESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIW 1950
            ++V  LKGH  KI  V++  ++  +I+   D  +  W   T +     RC E  +     TG+S+   G    +  +DK     +I   ++L +V ++ +V LTT      G +   GT +  ++ +   L +      + GH+  I+ +  + N  YL T +DD  V +W
Sbjct:  256 QMVAILKGHTKKITKVIYHPNEDTVITGSPDMNIRIWHVPTSQTQLLLRCHEGPV-----TGLSLHPTGDYLLSTSSDKHWAFSDIRTGRLLTKVIDTAEVGLTTAQFHPDGLIFGTGTVDSQVKIWD--LKEQSNVANFPGHTGPISAISFSENGYYLATAADDACVKLW 419          

Query:   52 LKHVFGFRVGVNGAIAYQN-EQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEF-------TSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFK 567
            LK V G  V  N A+        L YP G  +V++N  +++Q ++    +    T++A S   RYVA  E      P I +++L +        +   +  EF       T ++FSP  KYL    S  D ++  + W  + ++AS +++S  A      + F+ +D +    +GN   K
Sbjct:   25 LKKVLGLTVCSNAALDVSPVSGLLAYPAGCTVVLFNAKRQTQAYLVNTSRK-AFTSVAFSRCGRYVATGECGI--NPAIKVWELETPNGSLEHCSGGSVVAEFVDHKYAVTCVAFSPTGKYLVSVGSQHDMIVNVFDWRANLKMASNKISSKVA-----AVCFS-EDGSYFVTVGNRHVK 195          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNS--MRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNV-QVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQE 2964
            MA  AA   HVFG R GV   + Y +EQT+++PCG+N V YNIDQ+ Q+FI G E+S  M A+AIS NRRY+A++E    +K  I ++DL     R++K L+  E++ +EF  ++FSPDSKYL GQ  GPDW L  W WEK K +A+  +++   N  +NQ+SFNPQD+++IC  G   FK+F Y+   LK     K +S NFLCHTW++ E+V+ GT+TG+L++ E+G +R E N+ +    E   K + +    + + QVT IVS S GFA + G G V  FEKT+  + YKK R I IP    S D   ++ Q I+ +CISPSEET+VA T++ QLYS  LS  E+ K G+ + FE LS+SFH + I GL  C RKP+IAT ++DRSVRIWN+ETN LELYKEF EEAYS+ALHP+GLYILVGFSDKLRLM +L+DDI+ FKEF+IR C+EC FS+GGH FAAV+ N+I IYST  FE +++LKGHN K++ V ++ +D  L+SCGMDGAVYEW+T +G R  ES+LK+CSYTG++++ D K  +AVGTD +LKEI +SQ+L+E+ S DV  TTV LS SGR +F GT+ G++R  K+PL    +W EY  H+  ITKM IT +D +L+T+S+D  + IW++ DKEG+ +KR+K++ ++EEIL  K D +EK+  + EL  +V+EL+ +N+ QL LKD  YN+KI EL+EK +Q++ SL  + +VLK EKD ++  H + + +++E+H KEL D+ES+NNQKLMLEYEKYQELQ K   +Q++YE+QL  +E  K QALE++ + YE K  EK  ++     + + +  E+EE  R  EED D EI D ++KYE+ LREE++++++LK E    KK+F  LQ+EI++   EI+K + E Q+L+ VI++LE D  GLK  IQ RD  IQDKEK I+ LKKKN  L+K   V++++ + +++QIEP+E EIQ  K+Q+ E
Sbjct:    1 MATVAAP-SHVFGLRAGVKNNLLYLDEQTIIFPCGNNCVRYNIDQKFQRFIPGTERSQGMHALAISTNRRYLAVSE--CREKATITVFDLEQEQNRRRKVLTGGEMVVDEFVCMAFSPDSKYLIGQAGGPDWTLFLWMWEKKKVMATVNISN---NGPINQVSFNPQDNSKICVSGKGVFKIFHYAGETLKQTNAFKTDSHNFLCHTWMTTEQVLAGTETGQLMMFESGRLRWEINVTSVQKTESESKQQYSDEPFSALPQVTAIVSYSNGFACSMGQGTVCLFEKTEKADLYKKTRVIKIPPKRFSNDLSLTEKQKISTLCISPSEETLVASTDLGQLYSIHLSIAELQK-GECAYFEYLSHSFHNNIITGLSTCIRKPLIATSSLDRSVRIWNFETNVLELYKEFQEEAYSVALHPTGLYILVGFSDKLRLMTLLMDDIKIFKEFTIRNCRECTFSHGGHLFAAVNGNVINIYSTITFEEILNLKGHNEKVQAVAFSLNDSCLVSCGMDGAVYEWNTLSGTRESESILKTCSYTGVAISPDAKTFFAVGTDCSLKEIHNSQILKEMSSRDVVCTTVALSRSGRTIFIGTSTGTLRVIKYPLMIQNDWIEYQAHAGPITKMVITFDDQFLITVSEDGCLFIWKIIDKEGQGLKREKELIYSEEILTNKLDFDEKSKMLLELNAKVEELQEDNKCQLSLKDTEYNKKINELSEKCMQQIISLNAEKEVLKKEKDNQQEAHNKAISDILERHDKELHDMESSNNQKLMLEYEKYQELQLKLHNVQQEYEQQLHSMEESKTQALEDMMQSYEAKMEEKMILVNQYQDESQQRFKEFEEHIRQEEEDTDAEIHDIRMKYEQNLREEKKAHSKLKVELDTTKKRFHDLQREIENGNLEIEKLKQEVQRLQAVIKSLENDITGLKTAIQNRDGIIQDKEKNIFQLKKKNDTLNKTLEVMEFRAEYMQEQIEPKENEIQQQKDQMVE 974          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNS--MRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNV-QVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEK 2046
            MA  AA   HVFG R GV   + Y +EQT+++PCG+N V YNIDQ+ Q+FI G E+S  M A+AIS NRRY+A++E    +K  I ++DL     R++K L+  E++ +EF  ++FSPDSKYL GQ  GPDW L  W WEK K +A+  +++   N  +NQ+SFNPQD+++IC  G   FK+F Y+   LK     K +S NFLCHTW++ E+V+ GT+TG+L++ E+G +R E N+ +    E   K + +    + + QVT IVS S GFA + G G V  FEKT+  + YKK R I IP    S D   ++ Q I+ +CISPSEET+VA T++ QLYS  LS  E+ K G+ + FE LS+SFH + I GL  C RKP+IAT ++DRSVRIWN+ETN LELYKEF EEAYS+ALHP+GLYILVGFSDKLRLM +L+DDI+ FKEF+IR C+EC FS+GGH FAAV+ N+I IYST  FE +++LKGHN K++ V ++ +D  L+SCGMDGAVYEW+T +G R  ES+LK+CSYTG++++ D K  +AVGTD +LKEI +SQ+L+E+ S DV  TTV LS SGR +F GT+ G++R  K+PL    +W EY  H+  ITKM IT +D +L+T+S+D  + IW++ DKEG+ +KR+K++ ++EEIL  K D +EK
Sbjct:    1 MATVAAP-SHVFGLRAGVKNNLLYLDEQTIIFPCGNNCVRYNIDQKFQRFIPGTERSQGMHALAISTNRRYLAVSE--CREKATITVFDLEQEQNRRRKVLTGGEMVVDEFVCMAFSPDSKYLIGQAGGPDWTLFLWMWEKKKVMATVNISN---NGPINQVSFNPQDNSKICVSGKGVFKIFHYAGETLKQTNAFKTDSHNFLCHTWMTTEQVLAGTETGQLMMFESGRLRWEINVTSVQKTESESKQQYSDEPFSALPQVTAIVSYSNGFACSMGQGTVCLFEKTEKADLYKKTRVIKIPPKRFSNDLSLTEKQKISTLCISPSEETLVASTDLGQLYSIHLSIAELQK-GECAYFEYLSHSFHNNIITGLSTCIRKPLIATSSLDRSVRIWNFETNVLELYKEFQEEAYSVALHPTGLYILVGFSDKLRLMTLLMDDIKIFKEFTIRNCRECTFSHGGHLFAAVNGNVINIYSTITFEEILNLKGHNEKVQAVAFSLNDSCLVSCGMDGAVYEWNTLSGTRESESILKTCSYTGVAISPDAKTFFAVGTDCSLKEIHNSQILKEMSSRDVVCTTVALSRSGRTIFIGTSTGTLRVIKYPLMIQNDWIEYQAHAGPITKMVITFDDQFLITVSEDGCLFIWKIIDKEGQGLKREKELIYSEEILTNKLDFDEK 668          

Query:  121 VYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVA---LAETTSEDK---PVIVIYDLNSMRKKKTLSAPEILANEF-------TSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNL-KNFGIL-KVESQNF-LCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGF-SDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFA-AVHSNLIQIYSTT----NFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKR-CGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKP-GEWQEYLGHSAQITKMKITPNDDYLV-TISDDCVVMIWRV 1956
            VY   S +V+YN+D++ Q+  +G   +  +  +A+ P++  +A   +A T+S+ K   P + ++D        +L+   IL N F        S S S    +L       D +L  W W++  +LA  +     +N SV    F+P D+  I   G +    +   + +L K  G+  K E   F LC T+  +   I G  +G +++   G  R       SL ++ A   E +   L  ++  T+VS  K   +      + W       E ++K++ + +P       P ++ A+           ET++  T  + +   +L+   I     H++           ++ GL +   K    TC  D+ + +W+ +++Q    K   + A S   HPSG  + VG  + +  +++    D+ T             FS  G++ A   H N I IY+       +  V    GH+  I ++ W+ D + L+S   D  +  W  +  K+       +   +   + T  G + + +  D +             +  D+    V  S + R+L  G + G +  F FP ++       Y GHS+ +T +    +D +LV T   D  +M WRV
Sbjct:  250 VYFIASVVVLYNVDEQLQRHYTG--HTDDIKCLAVHPDKITIATGQVAGTSSDGKQLAPHVRVWD------SVSLNTLHILGNGFFDRALVCLSFSKSNGGSWLCVVDDSNDHMLSVWDWQREDRLAEVK----CSNESVFAADFHPTDANIIVTCGKSHLCFWSLEKGSLVKKQGLFEKQEKPKFVLCVTFSENGDAITGDSSGNILVWGKGSNRI------SLAIQGAH--EASVFALCMLRNGTLVSGGKDRKL------ISW------DENFQKIQTVEVP---ELYGPVRTVAE--------GRGETVLIGTTKNYVLQGSLNGEFIPITQGHTD-----------ELWGLTIHPLKHQFLTCGHDKHIYLWDSDSHQPIWTKTLEDSAQSAGFHPSGATVAVGMQTGRWLVLDTESKDLVTVHTDGNEQLSVIRFSPDGNFLAIGSHDNYIYIYAVAENGKKYSRVGKCSGHSSFITHLDWSVDSQYLVSNSGDYEILYWIPSVCKQVVSVETTRDIEWATFTCTL-GFHVFGLWPDGS-------------DGTDIN--AVCSSYAKRLLVTGDDFGKVHLFSFPCSQSRAPSHIYSGHSSHVTNVNFLFDDSHLVSTGGKDMSIMQWRV 816          

Query:  121 VYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVA---LAETTSEDK---PVIVIYDLNSMRKKKTLSAPEILANEF-------TSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNL-KNFGIL-KVESQNF-LCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGF-SDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFA-AVHSNLIQIYSTT----NFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKR-CGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKP-GEWQEYLGHSAQITKMKITPNDDYLV-TISDDCVVMIWRV 1956
            VY   S +V+YN+D++ Q+  +G   +  +  +A+ P++  +A   +A T+S+ K   P + ++D        +L+   IL N F        S S S    +L       D +L  W W++  +LA  +     +N SV    F+P D+  I   G +    +   + +L K  G+  K E   F LC T+  +   I G  +G +++   G  R       SL ++ A   E +   L  ++  T+VS  K   +      + W       E ++K++ + +P       P ++ A+           ET++  T  + +   +L+   I     H++           ++ GL +   K    TC  D+ + +W+ +++Q    K   + A S   HPSG  + VG  + +  +++    D+ T             FS  G++ A   H N I IY+       +  V    GH+  I ++ W+ D + L+S   D  +  W  +  K+       +   +   + T  G + + +  D +             +  D+    V  S + R+L  G + G +  F FP ++       Y GHS+ +T +    +D +LV T   D  +M WRV
Sbjct:  233 VYFIASVVVLYNVDEQLQRHYTG--HTDDIKCLAVHPDKITIATGQVAGTSSDGKQLAPHVRVWD------SVSLNTLHILGNGFFDRALVCLSFSKSNGGSWLCVVDDSNDHMLSVWDWQREDRLAEVK----CSNESVFAADFHPTDANIIVTCGKSHLCFWSLEKGSLVKKQGLFEKQEKPKFVLCVTFSENGDAITGDSSGNILVWGKGSNRI------SLAIQGAH--EASVFALCMLRNGTLVSGGKDRKL------ISW------DENFQKIQTVEVP---ELYGPVRTVAE--------GRGETVLIGTTKNYVLQGSLNGEFIPITQGHTD-----------ELWGLTIHPLKHQFLTCGHDKHIYLWDSDSHQPIWTKTLEDSAQSAGFHPSGATVAVGMQTGRWLVLDTESKDLVTVHTDGNEQLSVIRFSPDGNFLAIGSHDNYIYIYAVAENGKKYSRVGKCSGHSSFITHLDWSVDSQYLVSNSGDYEILYWIPSVCKQVVSVETTRDIEWATFTCTL-GFHVFGLWPDGS-------------DGTDIN--AVCSSYAKRLLVTGDDFGKVHLFSFPCSQSRAPSHIYSGHSSHVTNVNFLFDDSHLVSTGGKDMSIMQWRV 799          

Query:  121 VYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVA---LAETTSEDK---PVIVIYDLNSMRKKKTLSAPEILANEF-------TSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNL-KNFGIL-KVESQNF-LCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGF-SDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFA-AVHSNLIQIYSTT----NFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKR-CGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKP-GEWQEYLGHSAQITKMKITPNDDYLV-TISDDCVVMIWRV 1956
            VY   S +V+YN+D++ Q+  +G   +  +  +A+ P++  +A   +A T+S+ K   P + ++D        +L+   IL N F        S S S    +L       D +L  W W++  +LA  +     +N SV    F+P D+  I   G +    +   + +L K  G+  K E   F LC T+  +   I G  +G +++   G  R       SL ++ A   E +   L  ++  T+VS  K   +      + W       E ++K++ + +P       P ++ A+           ET++  T  + +   +L+   I     H++           ++ GL +   K    TC  D+ + +W+ +++Q    K   + A S   HPSG  + VG  + +  +++    D+ T             FS  G++ A   H N I IY+       +  V    GH+  I ++ W+ D + L+S   D  +  W  +  K+       +   +   + T  G + + +  D +             +  D+    V  S + R+L  G + G +  F FP ++       Y GHS+ +T +    +D +LV T   D  +M WRV
Sbjct:  242 VYFIASVVVLYNVDEQLQRHYTG--HTDDIKCLAVHPDKITIATGQVAGTSSDGKQLAPHVRVWD------SVSLNTLHILGNGFFDRALVCLSFSKSNGGSWLCVVDDSNDHMLSVWDWQREDRLAEVK----CSNESVFAADFHPTDANIIVTCGKSHLCFWSLEKGSLVKKQGLFEKQEKPKFVLCVTFSENGDAITGDSSGNILVWGKGSNRI------SLAIQGAH--EASVFALCMLRNGTLVSGGKDRKL------ISW------DENFQKIQTVEVP---ELYGPVRTVAE--------GRGETVLIGTTKNYVLQGSLNGEFIPITQGHTD-----------ELWGLTIHPLKHQFLTCGHDKHIYLWDSDSHQPIWTKTLEDSAQSAGFHPSGATVAVGMQTGRWLVLDTESKDLVTVHTDGNEQLSVIRFSPDGNFLAIGSHDNYIYIYAVAENGKKYSRVGKCSGHSSFITHLDWSVDSQYLVSNSGDYEILYWIPSVCKQVVSVETTRDIEWATFTCTL-GFHVFGLWPDGS-------------DGTDIN--AVCSSYAKRLLVTGDDFGKVHLFSFPCSQSRAPSHIYSGHSSHVTNVNFLFDDSHLVSTGGKDMSIMQWRV 808          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSM--RKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAA----------SLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQE-DVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKEL---EEAGRVMEMQRALIGQLRDKIVGME 3630
            M++  A   ++FG R  V   I Y +EQT+++P G+N V YN+DQ+ QKFI G EKS  M A+AISPNRRY+A++E   E K  + IYDL S+  +K+K LSAP++ A+EF SI+FSPDSKYL  Q+  P+W +I+W WEK K +A+ +  S +    + Q+SF+PQD+TQIC  G+  FK+FRY E N+K     KVE QNFLCHTW+S++RVI GTD GKL L E+G++R E N+ +          S   +E Q           V++  I++ SKGF  + G GKV  FEK +DK++YK+ R+I IP D  S DP +S+ Q I  MC+SPSEE ++  TN  QLYS  LSS EI+K G+ + FE L+ S+H S I GL +C RKP+IATC++DRSVRIWN+E N LELYKE+ EEAYS++LHPSGLY+LVGFSDKLR MN+LIDDIR+ KEF++RGCKECAFS+GGH FAAV+ N+I IY T  FE + +LKGHNGK+R+V W++DD KL+SCG+DGAVYEW+   GKR  E VLKSCSY+ ++++ D K  +AVG+D+TLKEISDSQ++RE+ S DV  T V +S+SGRM+F GT+ G+IRS K+PL    E+ EY  H+  +T++ +T +D YL+++S+D  +++W++ DKEGR +KRDK++G+AEE+LITKSDLEEKN  M EL+TRV+ELKMENEYQLRLKDMNYNEK+KELTEKFIQEME LKT NQ+LKT+ ++++ KH+E + E++EK S+E+QD+E++N+QKL+LEYEKYQELQ KSQRMQE+YE+QL ELE  K QALEE+TE+YE K  EK ++L+    + R    E+EETK+ IEED DREI D KI+YERRLREE+ES+ RLKGE+GIM+KKF+SLQKEI+++  +I+K + E QKL+ VI++LEKD +GLK+EIQERDETIQDKEKRIYDLKKKNQEL+KFKFVLDYKIKELKKQIEPRE EI+  KEQIQEMESELERFHKQN+QL LNI ELKQKLK+T++E+  ERQ  RD+EA V+RFKTDL+NCV +IQ+PK LK++I  LY K++Q+ DV+          VDADIQ+E+ RQREHLERS+++L+KKL+KD+EIHR D VR+MQENV+LIKEINDLR+ELK SRT  HDLEA LGL++K  +     +   ++    P+    L   EE  R+++MQR  I +LRD I   E
Sbjct:    1 MSVIVAQSHYIFGLRSPVTNNIFYFDEQTIIFPSGNNCVKYNVDQKWQKFIPGSEKSQGMQALAISPNRRYLAMSEKGLE-KATVTIYDLASVPFKKRKVLSAPDLTAHEFVSIAFSPDSKYLVAQSGFPEWQIIFWMWEKQKVMATVKPDSHSN--PIYQVSFSPQDNTQICTTGHGVFKLFRYLEGNMKQTNFQKVEPQNFLCHTWLSEDRVICGTDNGKLSLWESGDLRWEINIGSKSGQTDHEKHSAYSQELQVTSAEHAAPAPVRINAILAYSKGFLCSAGPGKVCMFEKVEDKDFYKRSRDIRIPQDEYSTDPTQSEQQEIVCMCLSPSEEMVLISTNKGQLYSIALSSAEISK-GEDAYFEYLTESWHSSSITGLSICVRKPLIATCSLDRSVRIWNFENNTLELYKEYQEEAYSVSLHPSGLYVLVGFSDKLRFMNLLIDDIRSVKEFTVRGCKECAFSHGGHLFAAVNGNVIHIYCTATFENITNLKGHNGKVRSVAWSSDDSKLVSCGLDGAVYEWNILLGKRESECVLKSCSYSSVAMSSDSKTIFAVGSDQTLKEISDSQIMREIPSFDVTYTAVAVSHSGRMIFTGTSLGTIRSMKYPLPLQKEFNEYQAHAKPVTRLVVTFDDQYLLSVSEDGCLILWKISDKEGRGLKRDKEVGYAEEVLITKSDLEEKNQVMLELKTRVEELKMENEYQLRLKDMNYNEKLKELTEKFIQEMEVLKTTNQILKTDSERQDIKHQEDVAELLEKQSREIQDLETSNSQKLLLEYEKYQELQLKSQRMQEEYEKQLHELEESKIQALEEITEHYEAKLQEKMSVLQLTQDESRQHLREFEETKKQIEEDGDREIQDMKIRYERRLREEKESSLRLKGESGIMRKKFSSLQKEIEERAADIEKMKAEQQKLQGVIKSLEKDILGLKREIQERDETIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPRENEIKEMKEQIQEMESELERFHKQNSQLDLNIAELKQKLKATDREMHKERQKVRDIEAVVKRFKTDLHNCVGFIQEPKMLKDNIRELYSKYVQDSDVAEI------VGVDADIQREYARQREHLERSLSTLQKKLAKDTEIHRTDNVRVMQENVTLIKEINDLRRELKLSRTKVHDLEAILGLNKKTRKNNATELKVSSSEGLHPVGVLRLNSEEETDRIIDMQRLEIKRLRDLIQSQE 1206          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSM--RKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLEN---------NQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQE---------------------MESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQE-DVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRK-QGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGME 3630
            M++  A   ++FG R  V   I Y +EQT+++P G+N V YN+DQ+ QKFI G EKS  M A+AISPNRRY+A++E   E K  + IYDL S+  +K+K LSAP++ A+EF SI+FSPDSKYL  Q+  P+W +I+W WEK K +A+ +  S +    + Q+SF+PQD+TQIC  G+  FK+FRY E N+K     KVE QNFLCHTW+S++RVI GTD GKL L E+G++R E N+ +   +  + +L +                V++  I++ SKGF  + G GKV  FEK +DK++YK+ R+I IP D  S DP +S+ Q I  MC+SPSEE ++  TN  QLYS  LSS EI+K G+ + FE L+ S+H S I GL +C RKP+IATC++DRSVRIWN+E N LELYKE+ EEAYS++LHPSGLY+LVGFSDKLR MN+LIDDIR+ KEF++RGCKECAFS+GGH FAAV+ N+I IY T  FE + +LKGHNGK+R+V W++DD KL+SCG+DGAVYEW+   GKR  E VLKSCSY+ ++++ D K  +AVG+D+TLKEISDSQ++RE+ S DV  T V +S+SGRM+F GT+ G+IRS K+PL    E+ EY  H+  +T++ +T +D YL+++S+D  +++W++ DKEGR +KRDK++G+AEE+LITKSDLEEKN  M EL+TRV+ELKMENEYQLRLKDMNYNEK+KELTEKFIQEME LKT NQ+LKT+ ++++ KH+E + E++EK S+E+QD+E++N+QKL+LEYEKYQELQ KSQRMQE+YE+QL ELE  K QALEE+TE+YE K  EK ++L+    + R    E+EETK+ IEED DREI D KI+YERRLREE+ES+ RLKGE+GIM+KKF+SLQKEI+++  +I+K + E QKL+ VI++LEKD +GLK+EIQERDETIQDKEKRIYDLKKKNQEL+KFKFVLDYKIKELKKQIEPRE EI+  KEQIQE                     MESELERFHKQN+QL LNI ELKQKLK+T++E+  ERQ  RD+EA V+RFKTDL+NCV +IQ+PK LK++I  LY K++Q+ DV+          VDADIQ+E+ RQREHLERS+++L+KKL+KD+EIHR D VR+MQENV+LIKEINDLR+ELK SRT  HDLEA LGL++K +   A +L           L     EE  R+++MQR  I +LRD I   E
Sbjct:    1 MSVIVAQSHYIFGLRSPVTNNIFYFDEQTIIFPSGNNCVKYNVDQKWQKFIPGSEKSQGMQALAISPNRRYLAMSEKGLE-KATVTIYDLASVPFKKRKVLSAPDLTAHEFVSIAFSPDSKYLVAQSGFPEWQIIFWMWEKQKVMATVKPDSHSN--PIYQVSFSPQDNTQICTTGHGVFKLFRYLEGNMKQTNFQKVEPQNFLCHTWLSEDRVICGTDNGKLSLWESGDLRWEINIGSKSGIYRSTELSSCFVFRVTSAEHAAPAPVRINAILAYSKGFLCSAGPGKVCMFEKVEDKDFYKRSRDIRIPQDEYSTDPTQSEQQEIVCMCLSPSEEMVLISTNKGQLYSIALSSAEISK-GEDAYFEYLTESWHSSSITGLSICVRKPLIATCSLDRSVRIWNFENNTLELYKEYQEEAYSVSLHPSGLYVLVGFSDKLRFMNLLIDDIRSVKEFTVRGCKECAFSHGGHLFAAVNGNVIHIYCTATFENITNLKGHNGKVRSVAWSSDDSKLVSCGLDGAVYEWNILLGKRESECVLKSCSYSSVAMSSDSKTIFAVGSDQTLKEISDSQIMREIPSFDVTYTAVAVSHSGRMIFTGTSLGTIRSMKYPLPLQKEFNEYQAHAKPVTRLVVTFDDQYLLSVSEDGCLILWKISDKEGRGLKRDKEVGYAEEVLITKSDLEEKNQVMLELKTRVEELKMENEYQLRLKDMNYNEKLKELTEKFIQEMEVLKTTNQILKTDSERQDIKHQEDVAELLEKQSREIQDLETSNSQKLLLEYEKYQELQLKSQRMQEEYEKQLHELEESKIQALEEITEHYEAKLQEKMSVLQLTQDESRQHLREFEETKKQIEEDGDREIQDMKIRYERRLREEKESSLRLKGESGIMRKKFSSLQKEIEERAADIEKMKAEQQKLQGVIKSLEKDILGLKREIQERDETIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPRENEIKEMKEQIQEVRFKRIHFLVFVSLHSSCSSPMESELERFHKQNSQLDLNIAELKQKLKATDREMHKERQKVRDIEAVVKRFKTDLHNCVGFIQEPKMLKDNIRELYSKYVQDSDVAEI------VGVDADIQREYARQREHLERSLSTLQKKLAKDTEIHRTDNVRVMQENVTLIKEINDLRRELKLSRTKVHDLEAILGLNKKTRKNNATELKGMHFCLSFIFLRLNSEEETDRIIDMQRLEIKRLRDLIQSQE 1224          

Query:   52 LKHVFGFR-VGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNL----KNFG-ILKVESQNFLCHTWVSDERVIL-GTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDK--EYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLEL-YKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRG--CKECAFSY-GGHYFA-AVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKL-ISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTK-PGEWQEYLGHSAQITKMKITPNDDYLVTISD-DCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEER 2250
            LK V G+R       + Y     +VY   +  V+Y+  Q SQ+F  G +    + ++AI P + YVA  +   +    I ++D  +++    L          +++ FS D K L       +  ++YW W+K +++A TR         +  +  NP  + ++  +G    K ++ +          FG I K+E+   +C ++   E ++  G  TG + + ++            ++L +  K  +         V  + +  KGF      G V  ++   ++  + Y   R  L P          S+  ++ D   +PS   I A T  H        + EI ++       LL       ++ GL    + P+ AT + D+++RIW   +    L  ++  +     A  P G  + VG SD   L+ +  D +     F  R     +  FS   G Y A A H N + IY+  + + V   KG +  I ++ W T  K L ++ G    ++ ++   GKR    V+K+     I       +T+      T + I  +       S    +   +L+   + L  G + G ++ F +P+     ++++Y+GHSA +T ++   +D  L+T+   D  +MIW  +                         LE K     E  T  +E    +    R K ++Y  KI  ++   I+EME  K   Q+       +EA  EER
Sbjct:  679 LKFVHGYRGYDCRNNLFYTQAGEVVYHVAAIAVVYDRLQHSQRFYLGHDDD--ILSLAIHPVKDYVATGQVGRD--AAIHVWDTQTLKCLSLLKGQH--QRGVSALDFSADGKCLVSVGLDDNHTIVYWDWKKGEKIACTR----GHKDKIFVVKCNPHHTDKLVTVGMKHIKFWQQTGGGFTAKRGTFGTIGKLET--MMCVSYGRAEDLVFSGAATGDIYIWKD------------VVLLKTIKAHDGP-------VFAMYALDKGFVTGGKDGVVELWDDMFERCLKTYAIKRAALSP---------SSKGLLLED---NPS---IRAITLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLATHPQLPLCATVSDDKTLRIWELSSQHRMLAVRKLKKGGRCCAFSPDGKALAVGLSDGSFLV-VNADTLEDMVSFHHRKEIIADIKFSPDAGKYLAVASHDNFVDIYNVLSSKRVGICKGASSYITHIDWDTRGKLLQVNSGAKEQLF-YEAPRGKR---YVIKAAEMEKIE-----WHTWTCVLGPTCEGIWPAH------SDITDVNAASLTKDRKALATGDDFGFVKLFSYPVKGCDAKFKKYVGHSAHVTNVRWLYDDSTLLTVGGADTALMIWTRE---------------------AFGSLENKPVDSEESDTDAEEDGGYDSDVAREKSIDYTTKIYAVS---IREMEGTKPHQQL-------KEASAEER 1335          

Query:   52 LKHVFGFR-VGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNL----KNFG-ILKVESQNFLCHTWVSDERVIL-GTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDK--EYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLEL-YKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRG--CKECAFSY-GGHYFA-AVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKL-ISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTK-PGEWQEYLGHSAQITKMKITPNDDYLVTISD-DCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEER 2250
            LK V G+R       + Y     +VY   +  V+Y+  Q SQ+F  G +    + ++AI P + YVA  +   +    I ++D  +++    L          +++ FS D K L       +  ++YW W+K +++A TR         +  +  NP  + ++  +G    K ++ +          FG I K+E+   +C ++   E ++  G  TG + + ++            ++L +  K  +         V  + +  KGF      G V  ++   ++  + Y   R  L P          S+  ++ D   +PS   I A T  H        + EI ++       LL       ++ GL    + P+ AT + D+++RIW   +    L  ++  +     A  P G  + VG SD   L+ +  D +     F  R     +  FS   G Y A A H N + IY+  + + V   KG +  I ++ W T  K L ++ G    ++ ++   GKR    V+K+     I       +T+      T + I  +       S    +   +L+   + L  G + G ++ F +P+     ++++Y+GHSA +T ++   +D  L+T+   D  +MIW  +                         LE K     E  T  +E    +    R K ++Y  KI  ++   I+EME  K   Q+       +EA  EER
Sbjct:  679 LKFVHGYRGYDCRNNLFYTQAGEVVYHVAAIAVVYDRLQHSQRFYLGHDDD--ILSLAIHPVKDYVATGQVGRD--AAIHVWDTQTLKCLSLLKGQH--QRGVSALDFSADGKCLVSVGLDDNHTIVYWDWKKGEKIACTR----GHKDKIFVVKCNPHHTDKLVTVGMKHIKFWQQTGGGFTAKRGTFGTIGKLET--MMCVSYGRAEDLVFSGAATGDIYIWKD------------VVLLKTIKAHDGP-------VFAMYALDKGFVTGGKDGVVELWDDMFERCLKTYAIKRAALSP---------SSKGLLLED---NPS---IRAITLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLATHPQLPLCATVSDDKTLRIWELSSQHRMLAVRKLKKGGRCCAFSPDGKALAVGLSDGSFLV-VNADTLEDMVSFHHRKEIIADIKFSPDAGKYLAVASHDNFVDIYNVLSSKRVGICKGASSYITHIDWDTRGKLLQVNSGAKEQLF-YEAPRGKR---YVIKAAEMEKIE-----WHTWTCVLGPTCEGIWPAH------SDITDVNAASLTKDRKALATGDDFGFVKLFSYPVKGCDAKFKKYVGHSAHVTNVRWLYDDSTLLTVGGADTALMIWTRE---------------------AFGSLENKPVDSEESDTDAEEDGGYDSDVAREKSIDYTTKIYAVS---IREMEGTKPHQQL-------KEASAEER 1335          

Query: 1717 REVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLT-KPGEWQEYLGHSAQITKMKITPNDDYLV-TISDDCVVMIWR 1953
            R  +  DV    V  S++G  +  G + G ++ F FP T K  + + Y GHSA +T ++ + +D Y++ T  DDC V +WR
Sbjct: 1878 RNADKADVNCACV--SHAGINVVTGDDFGLVKLFDFPCTEKFAKHKRYFGHSAHVTNVRFSHDDKYIISTGGDDCSVFVWR 1956          

Query:   52 LKHVFGFRVGV-NGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSED-KPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMF---------RYSENNLKNF----GILKVESQN-------FLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAAS----------LILEEAQKLENNQG----VLNNVQ----VTTIVSSSKG--FAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIY--STTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLK--EISDSQVLREVE-SVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEY-LGHSAQITKMKITPNDDYLVTISDDCVVMIW 1950
            L+ + GF   V +G I++ + + L+YP G  +++ N+  R Q+F+ G   ++ ++ +A S + RY+A  + T    K  I+++D         L+  ++   +  +++FSP+  YL       D  ++ W   K + +  +  +S ++  +   I  N  D   +   GN   +++         R +E  L         L+V SQ+       F C T   D   IL  +T   +L      + +F+L  +          L+     KL   +G        VQ    VT+I    +G  F V  G  +++ F        Y + +E LI             ++ IND+        + A          T S  +I      ++ ELL  +      L +D  R    I +   D  +R +  E+ +L    E A        H  G+  +   SD  R++                       S GG          ++I+  S     +V S+K H   +  +    ++++ ++   DG    WD     R  + VL +  +  +    +       GTD+ +   E+ D   +RE+E S    +  + + + G     G ++  ++ + +     GE     +GHS  IT++KI P   Y++++S D  ++ W
Sbjct:   12 LQGIIGFNGHVPSGLISHPDREHLIYPLGCTVIIENLSSRKQQFLQG--HTNNVSCVAASRSGRYLASGQVTYMGFKADILLWDYGRREACAKLTLHKV---KVEALAFSPNDLYLVSLGGQDDGSVVVWNVAKREAICGSPASSLSSGHATTIIFTNNSDDIFMTG-GNGTLRVWDVDLPNRKMRPTECQLGQMKRVVTCLQVTSQSCFTDDSCFYCGTSSGD---ILTINTKSKLLSSFAPQKGKFSLGVTALRLLKTGELLVGSGDGKLALCKGPNYKAAKTVQLQGSVTSISLRGQGHQFFVGTGGAQIYRFS-------YPEFKEELIAT---------CHSEAINDIAFPFGTSELFA----------TCSKNDIRVWHTATHKELLRITVPNMTCLAIDFMRDGKSIISAWNDGRIRAFMPESGRLMYCIENA--------HSMGVTAIAATSDCKRIV-----------------------SGGGE-------GQVRIWEISKETQRLVQSMKEHKSSVTCIKLKGNNRECLTASSDGTCIIWDIVRFTRL-QMVLSNTLFRCVCYHPEEFQFVTSGTDRKVGYWEVFDGSAIRELEGSKSGAINGMDICDQGAHFVTGGDDKLVKVWDY---NEGEVTHVGIGHSGNITRLKICPLSKYIISVSTDGAILCW 615          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSM--RKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNL-------AASL-ILEEAQKLENNQGVLNNV------------------QVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRK--QGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKI 3618
            M+   A   HVFG R  V   + + +EQ +++P G++ V YNIDQ+ QKFI+G +KS  M A+AISPNRRY+A++ET  E KP + IY+L+S+  RK+K L+  +    +FTS++FSPDSKYL  QTS PD  L+YW WEK K +A  +  S   N  + Q+S + QD++Q+C  G+  FK+ R++E  LK     + ES N+L H WVS++RVI+GTDTGKL L E+G+ R E ++       + SL +++E++ L     + + V                  QV  I + SKGFA + G G+V  FEK ++K++Y++ REI IP D  S DP +S  Q +  +C SPSEET++A TN +QLYS T+S TEI+K G+ ++FE L Y  H + I GLD C RKP+IATC++DRSVRIWNYE+N LELYKE+ EEAY+++LHPSG YI+VGF+DKLRLMN+LIDDIR FKE+S+RGCKEC+FS GGH FAAV+ N+I I++TT+ E +  LKGH GKIR++VW  DD KL+S G DGAVYEW+ +TGKR  E VLKSCSY  ++ + D K  +AVG+D+TLKEISDS +LRE+ + DV  T++T+S+SGRM+F GT+ G+IR+ K+PL+   E+ EY  H+  + KM +T +D +L+T+ +D  +  W+V DK+GR +KR++++G+AEE+L+TK+D+EEK   M EL+TRV+ELKMENEYQLRLKDMNY EKIKELT+KFIQEMESLKTKNQVLKTEK+K++  H ERL E+++K ++ELQD+E  NNQKL+LEYEKYQELQ KSQRMQE+YE+QL++ +  K QALEELTE+YE K  EK+ +LE   +D+R Q  E+EETK+ IEED DREI D K KYER+LR+E+ESN RLKGETGIM+KKF+SLQKEI+++  +I+  ++E  KL+ +IR+LEKD  GLK+EIQERDETIQDKEKRIYDLKKKNQEL+KFKFVLDYKIKELKKQIEPRE EI+  KEQIQEME+ELERFHKQN QL LNI EL QKL++T++E++ E+Q  RD+EA VRRFKTDL+NCV+YIQ+P  LKE I  L++K++Q            A +++D+Q+E+ RQREHLER++A+L+KK+ K+ E+HR DYVRIMQENVSLIKEIN+LR+ELK +R+  +DLE+AL + +K    E    +++         +   E EE GR++EMQR  I +LRD+I
Sbjct:    1 MSTVVAQALHVFGLRPHVTNNVFFFDEQIIIFPSGNHCVKYNIDQKWQKFIAGSDKSQGMLALAISPNRRYLAISETVQE-KPAVTIYELSSIPCRKRKVLNNFDFQVQKFTSMAFSPDSKYLLTQTSPPDSNLVYWLWEKQKVMAIIKADS--QNNPIYQVSISSQDNSQVCITGSGVFKLLRFAEGTLKQINFQRGESSNYLAHAWVSEDRVIVGTDTGKLFLFESGDQRWETSIMVKESTSSRSLEVIQESESLIEFPPLSSPVSSVERMDITTNTQQQAMPQVFAIAAYSKGFACSAGPGRVLLFEKVEEKDFYRESREIRIPTDQQSNDPSQSDKQDVLCLCFSPSEETLIASTNKNQLYSITMSLTEISK-GEAAHFEYLLYPLHSASITGLDTCIRKPLIATCSLDRSVRIWNYESNTLELYKEYQEEAYTVSLHPSGHYIVVGFADKLRLMNLLIDDIRPFKEYSVRGCKECSFSNGGHLFAAVNGNVIHIFTTTSLENINILKGHTGKIRSLVWNLDDSKLVSAGTDGAVYEWNLSTGKRETECVLKSCSYNSVTTSPDAKVIFAVGSDQTLKEISDSLILREIPAFDVIYTSITISHSGRMIFVGTSVGTIRAMKYPLSLQKEYNEYQAHAGPVMKMLLTFDDQFLLTVGEDGCLFTWKVFDKDGRGIKREREVGFAEEVLVTKTDMEEKAQIMLELKTRVEELKMENEYQLRLKDMNYTEKIKELTDKFIQEMESLKTKNQVLKTEKEKQDISHRERLEELVDKQTRELQDLECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTGLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYERKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIELLKSEQMKLQGIIRSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPRENEIKVMKEQIQEMEAELERFHKQNTQLELNITELLQKLRATDQEMRKEQQKERDLEALVRRFKTDLHNCVAYIQEPGLLKEKIRGLFEKYVQR-----ADMVEIAGLNSDLQQEYARQREHLERNLATLKKKVIKEGELHRTDYVRIMQENVSLIKEINELRRELKLTRSQIYDLESALKVSKKTRSQEVPESVISKDVVGSTSTMRLNEQEETGRIIEMQRLEIRRLRDQI 1217          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSM--RKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNL-------AASL-ILEEAQKLENNQGVLNNV------------------QVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRK--QGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKI 3618
            M+   A   HVFG R  V   + + +EQ +++P G++ V YNIDQ+ QKFI+G +KS  M A+AISPNRRY+A++ET  E KP + IY+L+S+  RK+K L+  +    +FTS++FSPDSKYL  QTS PD  L+YW WEK K +A  +  S   N  + Q+S + QD++Q+C  G+  FK+ R++E  LK     + ES N+L H WVS++RVI+GTDTGKL L E+G+ R E ++       + SL +++E++ L     + + V                  QV  I + SKGFA + G G+V  FEK ++K++Y++ REI IP D  S DP +S  Q +  +C SPSEET++A TN +QLYS T+S TEI+K G+ ++FE L Y  H + I GLD C RKP+IATC++DRSVRIWNYE+N LELYKE+ EEAY+++LHPSG YI+VGF+DKLRLMN+LIDDIR FKE+S+RGCKEC+FS GGH FAAV+ N+I I++TT+ E +  LKGH GKIR++VW  DD KL+S G DGAVYEW+ +TGKR  E VLKSCSY  ++ + D K  +AVG+D+TLKEISDS +LRE+ + DV  T++T+S+SGRM+F GT+ G+IR+ K+PL+   E+ EY  H+  + KM +T +D +L+T+ +D  +  W+V DK+GR +KR++++G+AEE+L+TK+D+EEK   M EL+TRV+ELKMENEYQLRLKDMNY EKIKELT+KFIQEMESLKTKNQVLKTEK+K++  H ERL E+++K ++ELQD+E  NNQKL+LEYEKYQELQ KSQRMQE+YE+QL++ +  K QALEELTE+YE K  EK+ +LE   +D+R Q  E+EETK+ IEED DREI D K KYER+LR+E+ESN RLKGETGIM+KKF+SLQKEI+++  +I+  ++E  KL+ +IR+LEKD  GLK+EIQERDETIQDKEKRIYDLKKKNQEL+KFKFVLDYKIKELKKQIEPRE EI+  KEQIQEME+ELERFHKQN QL LNI EL QKL++T++E++ E+Q  RD+EA VRRFKTDL+NCV+YIQ+P  LKE I  L++K++Q            A +++D+Q+E+ RQREHLER++A+L+KK+ K+ E+HR DYVRIMQENVSLIKEIN+LR+ELK +R+  +DLE+AL + +K    E    +++         +   E EE GR++EMQR  I +LRD+I
Sbjct:    1 MSTVVAQALHVFGLRPHVTNNVFFFDEQIIIFPSGNHCVKYNIDQKWQKFIAGSDKSQGMLALAISPNRRYLAISETVQE-KPAVTIYELSSIPCRKRKVLNNFDFQVQKFTSMAFSPDSKYLLTQTSPPDSNLVYWLWEKQKVMAIIKADS--QNNPIYQVSISSQDNSQVCITGSGVFKLLRFAEGTLKQINFQRGESSNYLAHAWVSEDRVIVGTDTGKLFLFESGDQRWETSIMVKESTSSRSLEVIQESESLIEFPPLSSPVSSVERMDITTNTQQQAMPQVFAIAAYSKGFACSAGPGRVLLFEKVEEKDFYRESREIRIPTDQQSNDPSQSDKQDVLCLCFSPSEETLIASTNKNQLYSITMSLTEISK-GEAAHFEYLLYPLHSASITGLDTCIRKPLIATCSLDRSVRIWNYESNTLELYKEYQEEAYTVSLHPSGHYIVVGFADKLRLMNLLIDDIRPFKEYSVRGCKECSFSNGGHLFAAVNGNVIHIFTTTSLENINILKGHTGKIRSLVWNLDDSKLVSAGTDGAVYEWNLSTGKRETECVLKSCSYNSVTTSPDAKVIFAVGSDQTLKEISDSLILREIPAFDVIYTSITISHSGRMIFVGTSVGTIRAMKYPLSLQKEYNEYQAHAGPVMKMLLTFDDQFLLTVGEDGCLFTWKVFDKDGRGIKREREVGFAEEVLVTKTDMEEKAQIMLELKTRVEELKMENEYQLRLKDMNYTEKIKELTDKFIQEMESLKTKNQVLKTEKEKQDISHRERLEELVDKQTRELQDLECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTGLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYERKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIELLKSEQMKLQGIIRSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPRENEIKVMKEQIQEMEAELERFHKQNTQLELNITELLQKLRATDQEMRKEQQKERDLEALVRRFKTDLHNCVAYIQEPGLLKEKIRGLFEKYVQR-----ADMVEIAGLNSDLQQEYARQREHLERNLATLKKKVIKEGELHRTDYVRIMQENVSLIKEINELRRELKLTRSQIYDLESALKVSKKTRSQEVPESVISKDVVGSTSTMRLNEQEETGRIIEMQRLEIRRLRDQI 1217          

Query:   52 LKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYS--------ENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETI-------------VACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHP-----SGLYILVGFSD 1308
            L H FG+       +   +  TL+Y  G+ +V+ +   ++Q ++        + A+ + P + Y A+AE  S   P I+IY+  S++  + L   +     +  + F+ +   LA     PD+ +  W W++ + +  T+    A +  V +++FNP +  Q+   G+   K +  +        + +L  FG  K  + +   +  + D +V+ G++ G L+L E   I+ E        ++       NQ +L+  +V T        A + G  ++  FE  D  +           +D    D G  + + IN++ I  S                 +A      ++   LS + IT+     + E L +SFH   I  L +     ++AT A+D SVR++++ +    ++ +F +   S+   P     S   I+VGF D
Sbjct:  123 LNHSFGYDCRKRANLQLLDSNTLLYVAGNQMVLLDFKDKTQIYLQS-SSGQGIGAIGVHPKKTYFAVAEKGS--FPKIIIYEYPSLKPYRILR--DGAEKAYAYVDFNNEGNLLASVGCHPDYTITIWGWKEEQPILRTK----AFSQDVFKVTFNPDNDEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFG--KTSTSDIEGYAELPDGKVLSGSEWGNLLLWEGSLIKVELCRTG---MKSCHSGSINQIMLDEGEVIT--------AGSDGSVRIWDFETIDTADV----------ID----DTGLLEIEPINELHIDKSVNLFSMIKMNEVGNNFWLAQDANGAIWKLDLSFSNITQ-----DPECL-FSFHSGPIAALAVSPLTYLMATTAMDCSVRVYDFSSKNPLVHMKFKQGGTSLIWAPRSVSVSASQIVVGFQD 525          

Query:   52 LKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYS--------ENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETI-------------VACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHP-----SGLYILVGFSD 1308
            L H FG+       +   +  TL+Y  G+ +V+ +   ++Q ++        + A+ + P + Y A+AE  S   P I+IY+  S++  + L   +     +  + F+ +   LA     PD+ +  W W++ + +  T+    A +  V +++FNP +  Q+   G+   K +  +        + +L  FG  K  + +   +  + D +V+ G++ G L+L E   I+ E        ++       NQ +L+  +V T        A + G  ++  FE  D  +           +D    D G  + + IN++ I  S                 +A      ++   LS + IT+     + E L +SFH   I  L +     ++AT A+D SVR++++ +    ++ +F +   S+   P     S   I+VGF D
Sbjct:  123 LNHSFGYDCRKRANLQLLDSNTLLYVAGNQMVLLDFKDKTQIYLQS-SSGQGIGAIGVHPKKTYFAVAEKGS--FPKIIIYEYPSLKPYRILR--DGAEKAYAYVDFNNEGNLLASVGCHPDYTITIWGWKEEQPILRTK----AFSQDVFKVTFNPDNDEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFG--KTSTSDIEGYAELPDGKVLSGSEWGNLLLWEGSLIKVELCRTG---MKSCHSGSINQIMLDEGEVIT--------AGSDGSVRIWDFETIDTADV----------ID----DTGLLEIEPINELHIDKSVNLFSMIKMNEVGNNFWLAQDANGAIWKLDLSFSNITQ-----DPECL-FSFHSGPIAALAVSPLTYLMATTAMDCSVRVYDFSSKNPLVHMKFKQGGTSLIWAPRSVSVSASQIVVGFQD 525          

Query:   31 MAIAAAHLKHVFGFRVGV-NGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSED-KPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVN---QISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQN-----FLCHTWVSDERVI--LGTDTGKL--------ILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQ----LYSF-------TLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSI-ALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIR----GCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLK--EISDSQVLREVE-SVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEY-LGHSAQITKMKITPNDDYLVTISDDCVVMIWR 1953
            + +A   L+ V GF   V NG   + +++ L+YP G  +++  I+   Q F+ G    + ++ + IS    Y+A  + T    K  I+++D    +K++ ++   +   +  +++FSP+  YL       D  ++ W+  K   +      SPAA  +V     + F+          GN   +++   E +L N  I   E Q       +  T ++D+     LGT TG +        +L + G ++ +F+L  S     A +     G+L        V S  G  + C   K   ++     +    +  I +  + +    G  ++ I   +  +  +ET++A  +       ++ F       T +  +I      S  ELL  +       G+D  R    I +   D  +R +  E+ +L          Y+I + H  G+  +   SD  R+       I    E  +R    GC+                       T   E  +  K H   +  +    ++++ ++   DG    WD    +R  + +L +  +  +    +       GTD+ +   E+ D  V+RE+E S+   +  + ++  G     G ++  ++ + +     GE     +GHS  I  M+I+P + Y+V++S D  ++ W+
Sbjct:    9 LDVAELELQAVIGFNGHVPNGLKCHPDQEHLIYPLGCTVLIQAINTNEQNFLHG--HGNNVSCVTISKEGDYIASGQVTFMGFKADIILWDF---KKRELIARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICG----SPAAGLNVGNATSVVFSRCRDEMFVTAGNGTIRVW---ELDLPNRKIWPTECQTGQMKRIVLSTGMADDDSFFYLGTTTGDILKMNPKTKLLADTGPVKDKFSLGVS-----ALRCLKMGGLL--------VGSGAGLLIFC---KSPSYKPIKKVQLQGGITSITLRGEGHQFFVGTEESHIYR-VNFTDFKETLIATCHFEAVQDIVFPFGTAELFATCAKKDIRVWHTMSKRELLRITVPNMTCHGIDFMRDGKSIISAWDDGKIRAFAPESGRL---------MYTINSAHRIGVTAIATTSDCKRI-------ISGGGEGEVRVWQVGCQ-----------------------TQKLEEAL--KEHKSSVSCIRVKKNNEECVTASTDGTCIIWDLVRLRR-NQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGSVIRELEGSLSGSINGMDITQEGGHFVTGGHDHLVKVWDY---NEGEVTHVGVGHSGNIMAMRISPGNQYIVSVSADGAILRWK 615          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSM--RKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEF--------NLAASL-ILEEAQKL------------------ENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRK-------QGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKI 3618
            M+   A   HVFG R  V   I Y +EQ +++P G++ V YN+DQ+ QKFI G EKS  M A++ISPNRRY+A++ET  E KP I IY+L+S+  RK+K L+  +    +F S++FSPDSKYL  QTS P+  L+YW WEK K +A  R+ +   N  V Q+SF+PQD+TQ+C  GN  FK+ R++E  LK     + E QN+L HTWV+D+++++GTDTGKL L E+G+ R E         N + SL +++E++ L                   ++   ++  QV  I + SKGFA + G G+V  FEK ++K++Y++ REI IPVD  S DP +S  Q +  +C SPSEET+VA T+ +QLYS T+S TEI+K G+ ++FE L Y  H + I GL  C RKP+IATC++DRS+R+WNYETN LEL+KE+ EEAYSI+LHPSG +I+VGF+DKLRLMN+LIDDIR+FKE+S+RGC EC+FS GGH FAAV+ N+I +Y+TT+ E + SLKGH GKIR++VW  DD KLIS G DGAVYEW+ +TGKR  E VLKSCSY  ++V+ D K  +AVG+D TLKEI+DS +LRE+ + DV  T + +S+SGRM+F GT+ G+IR+ K+PL    E+ EY  H+  ITKM +T +D +L+T ++D  +  W+V DK+GR +KR++++G+AEE+L+TK+D+EEK   M EL+TRV+ELKMENEYQLRLKDMNY+EKIKELT+KFIQEMESLKTKNQVL+TEK+K++  H E + ++++K S+ELQD+E  NNQKL+LEYEKYQELQ KSQRMQE+YE+QL++ +  K QALEELTE+YE K  EK+T+LE   +D+R Q  E+EETK+ IEED DREI D K KYE++LR+E+ESN RLKGETGIM+KKF+SLQKEI+++  +I+  + E  KL+ VI++LEKD  GLK+EIQERDETIQDKEKRIYDLKKKNQEL KFKFVLDYKIKELKKQIEPRE EI+  KEQIQEME+ELE FHKQN QL LNI EL QKL++T++E++ ERQ  RD+EA V+RFKTDL+NCV+YIQ+P+ LKE +  L++K++Q            A ++ D+Q+E+TRQREHLER++A+L+KK+ K+ E+HR DYVRIMQENVSLIKEIN+LR+ELK +R+  +DLEAAL L +K       + E +R +++     +       E EE GR++EMQR  I +LRD+I
Sbjct:    1 MSAVVAQTLHVFGLRSHVANNIFYFDEQIIIFPSGNHCVKYNVDQKWQKFIPGSEKSQGMLALSISPNRRYLAISETVQE-KPAITIYELSSIPCRKRKVLNNFDFQVQKFISMAFSPDSKYLLAQTSPPESNLVYWLWEKQKVMAIVRIDT--QNNPVYQVSFSPQDNTQVCVTGNGMFKLLRFAEGTLKQTSFQRGEPQNYLAHTWVADDKIVVGTDTGKLFLFESGDQRWETSIMVKEPTNGSKSLDVIQESESLIEFPPVSSPLPSYEQMVAASSHSQMSMPQVFAIAAYSKGFACSAGPGRVLLFEKMEEKDFYRESREIRIPVDPQSNDPSQSDKQDVLCLCFSPSEETLVASTSKNQLYSITMSLTEISK-GEPAHFEYLMYPLHSAPITGLATCIRKPLIATCSLDRSIRLWNYETNTLELFKEYQEEAYSISLHPSGHFIVVGFADKLRLMNLLIDDIRSFKEYSVRGCGECSFSNGGHLFAAVNGNVIHVYTTTSLENISSLKGHTGKIRSIVWNADDSKLISGGTDGAVYEWNLSTGKRETECVLKSCSYNCVTVSPDAKIIFAVGSDHTLKEIADSLILREISAFDVTYTAIVISHSGRMMFVGTSVGTIRAMKYPLPLQKEFNEYQAHAGPITKMLLTFDDQFLLTAAEDGCLFTWKVFDKDGRGIKREREVGFAEEVLVTKTDMEEKAQVMLELKTRVEELKMENEYQLRLKDMNYSEKIKELTDKFIQEMESLKTKNQVLRTEKEKQDVYHHEHIEDLLDKQSRELQDMECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTTLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYEKKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIETLKGEQMKLQGVIKSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELGKFKFVLDYKIKELKKQIEPRENEIRVMKEQIQEMEAELENFHKQNTQLELNITELWQKLRATDQEMRRERQKERDLEALVKRFKTDLHNCVAYIQEPRLLKEKVRGLFEKYVQR-----ADMVEIAGLNTDLQQEYTRQREHLERNLATLKKKVVKEGELHRTDYVRIMQENVSLIKEINELRRELKFTRSQVYDLEAALKLTKKVRPQEVSETEPSRDMLSTAPTARL-----NEQEETGRIIEMQRLEIQRLRDQI 1218          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSM--RKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNL-------AASL-ILEEAQKLENNQGVLNNV------------------QVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRK--QGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKI 3618
            M+   A   HVFG R  V   + + +EQ +++P G++ V YNIDQ+ QKFI+G +KS  M A+AISPNRRY+A++ET  E KP + IY+L+S+  RK+K L+  +    +FTS++FSPDSKYL  QTS PD  L+YW WEK K +A  +  S   N  + Q+S + QD++Q+C  G+  FK+ R++E  LK     + ES N+L H WVS++RVI+GTDTGKL L E+G+ R E ++       + SL +++E++ L     + + V                  QV  I + SKGFA + G G+V  FEK ++K++Y++ REI IP D  S DP +S  Q +  +C SPSEET++A TN +QLYS T+S TEI+K G+ ++FE L Y  H + I GLD C RKP+IATC++DRSVRIWNYE+N LELYKE+ EEAY+++LHPSG YI+VGF+DKLRLMN+LIDDIR FKE+S+RGCKEC+FS GGH FAAV+ N+I I++TT+ E +  LKGH GKIR++VW  DD KL+S G DGAVYEW+ +TGKR  E VLKSCSY  ++ + D K  +AVG+D+TLKEISDS +LRE+ + DV  T++T+S+SGRM+F GT+ G+IR+ K+PL+   E+ EY  H+  + KM +T +D +L+T+ +D  +  W+V DK+GR +KR++++G+AEE+L+TK+D+EEK   M EL+TRV+ELKMENEYQLRLKDMNY EKIKELT+KFIQEMESLKTKNQVLKTEK+K++  H ERL E+++K ++ELQD+E  NNQKL+LEYEKYQELQ KSQRMQE+YE+QL++ +  K QALEELTE+YE K  EK+ +LE   +D+R Q  E+EETK+ IEED DREI D K KYER+LR+E+ESN RLKGETGIM+KKF+SLQKEI+++  +I+  ++E  KL+ +IR+LEKD  GLK+EIQERDETIQDKEKRIYDLKKKNQEL+KFKFVLDYKIKELKKQIEPRE EI+  KEQIQEME+ELERFHKQN QL LNI EL QKL++T++E++ E+Q  RD+EA VRRFKTDL+NCV+YIQ+P  LKE I  L++K++Q            A +++D+Q+E+ RQREHLER++A+L+KK+ K+ E+HR DYVRIMQENVSLIKEIN+LR+ELK +R+  +DLE+AL + +K    E    +++         +   E EE GR++EMQR  I +LRD+I
Sbjct:    1 MSTVVAQALHVFGLRPHVTNNVFFFDEQIIIFPSGNHCVKYNIDQKWQKFIAGSDKSQGMLALAISPNRRYLAISETVQE-KPAVTIYELSSIPCRKRKVLNNFDFQVQKFTSMAFSPDSKYLLTQTSPPDSNLVYWLWEKQKVMAIIKADS--QNNPIYQVSISSQDNSQVCITGSGVFKLLRFAEGTLKQINFQRGESSNYLAHAWVSEDRVIVGTDTGKLFLFESGDQRWETSIMVKESTSSRSLEVIQESESLIEFPPLSSPVSSVERMDITTNTQQQAMPQVFAIAAYSKGFACSAGPGRVLLFEKVEEKDFYRESREIRIPTDQQSNDPSQSDKQDVLCLCFSPSEETLIASTNKNQLYSITMSLTEISK-GEAAHFEYLLYPLHSASITGLDTCIRKPLIATCSLDRSVRIWNYESNTLELYKEYQEEAYTVSLHPSGHYIVVGFADKLRLMNLLIDDIRPFKEYSVRGCKECSFSNGGHLFAAVNGNVIHIFTTTSLENINILKGHTGKIRSLVWNLDDSKLVSAGTDGAVYEWNLSTGKRETECVLKSCSYNSVTTSPDAKVIFAVGSDQTLKEISDSLILREIPAFDVIYTSITISHSGRMIFVGTSVGTIRAMKYPLSLQKEYNEYQAHAGPVMKMLLTFDDQFLLTVGEDGCLFTWKVFDKDGRGIKREREVGFAEEVLVTKTDMEEKAQIMLELKTRVEELKMENEYQLRLKDMNYTEKIKELTDKFIQEMESLKTKNQVLKTEKEKQDISHRERLEELVDKQTRELQDLECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTGLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYERKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIELLKSEQMKLQGIIRSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPRENEIKVMKEQIQEMEAELERFHKQNTQLELNITELLQKLRATDQEMRKEQQKERDLEALVRRFKTDLHNCVAYIQEPGLLKEKIRGLFEKYVQR-----ADMVEIAGLNSDLQQEYARQREHLERNLATLKKKVIKEGELHRTDYVRIMQENVSLIKEINELRRELKLTRSQIYDLESALKVSKKTRSQEVPESVISKDVVGSTSTMRLNEQEETGRIIEMQRLEIRRLRDQI 1217          

Query:   52 LKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYS--------ENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETI-------------VACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHP-----SGLYILVGFSD 1308
            L H FG+       +   +  TL+Y  G+ +V+ +   ++Q ++        + A+ + P + Y A+AE  S   P I+IY+  S++  + L   +     +  + F+ +   LA     PD+ +  W W++ + +  T+    A +  V +++FNP +  Q+   G+   K +  +        + +L  FG  K  + +   +  + D +V+ G++ G L+L E   I+ E        ++       NQ +L+  +V T        A + G  ++  FE  D  +           +D    D G  + + IN++ I  S                 +A      ++   LS + IT+     + E L +SFH   I  L +     ++AT A+D SVR++++ +    ++ +F +   S+   P     S   I+VGF D
Sbjct:  123 LNHSFGYDCRKRANLQLLDSNTLLYVAGNQMVLLDFKDKTQIYLQS-SSGQGIGAIGVHPKKTYFAVAEKGS--FPKIIIYEYPSLKPYRILR--DGAEKAYAYVDFNNEGNLLASVGCHPDYTITIWGWKEEQPILRTK----AFSQDVFKVTFNPDNDEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFG--KTSTSDIEGYAELPDGKVLSGSEWGNLLLWEGSLIKVELCRTG---MKSCHSGSINQIMLDEGEVIT--------AGSDGSVRIWDFETIDTADV----------ID----DTGLLEIEPINELHIDKSVNLFSMIKMNEVGNNFWLAQDANGAIWKLDLSFSNITQ-----DPECL-FSFHSGPIAALAVSPLTYLMATTAMDCSVRVYDFSSKNPLVHMKFKQGGTSLIWAPRSVSVSASQIVVGFQD 525          

Query:   52 LKHVFGFRVGV-NGAIAYQNEQTLVYPCGSNLVMYN-IDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPV-IVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLK------NFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQ--VTTIVSSSKG-FAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSST--EITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAE--EAYSIALHPSGLYILVGFSD-KLRLMNI----LIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIY--STTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDK--TLKEISDSQVLREVESVDV-QLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEY---LGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQ 1959
            L  V GF   + NG IA+ + +T++YP GS +V+ +  D RSQ+F+ G   S K++ +A+S + RY+A  + T       I+I+DL S +    ++  ++   +  ++ FS D ++LA      D  L+ W       +      SP      N + F      ++   GN    ++ Y   N K        G LK   ++ +     +DE    GT TG ++                 I  E    +N      NVQ  VT       G   V  G G +    K              +P  + +   G   +  + DM  +    T    T +  +Y    S    E+ +   +     +++   YS++            ATC     +R+W+  T + EL +      E + IA    G  IL G+SD K+R        +I  I    + ++      A S      +     +++++    T+  +  S+K H G +  +       + +S   DG+   WD +T KR   S+  +  +  +    D       GTD+  T  +  D   +R ++  D+ ++  + +   G  L  G  +  ++ + +      E   Y   + HS  IT + +TP+   +V++  +  + IW  Q
Sbjct:    7 LNSVIGFGGAIENGLIAHPDGRTIIYPLGSTIVLRDRADPRSQEFLQG--HSDKVSCLALSRSGRYLASGQITYMGFTADIIIWDLESKQLIHRMALHKV---KVQALDFSCDERFLASLGGQDDNALVLWDVASGNAICG----SPCNTNFTNCVKFFNNSPDKLITAGNFNMNVWTYDAGNNKLRPTDATLGTLKRVFKSVVVD--ANDEYAYCGTTTGDVL----------------QIALERVLFKNTGPAKGNVQMGVTATCEVPTGDILVGGGDGSLQLLRK--------------MPALAGTKVEGAITSIALADM--NARGFTFFVGTAMCNIYKPATSRLKEELVQTAHNDKINGMAFPNEYSEVF-----------ATCGTG-FIRLWHLTTCR-ELLRIAVPNLECFCIAFTTDGSAILSGWSDGKIRAFGPQSGKIIFTINDAHQKAVTAIASTADS--SRILSGGEEGMVRVWRIGRTSQTLEASMKDHKGPVNCIRIKGSGDECVSASSDGSCILWDLHTFKR-RTSLFANTFFKSVVYHPDESQLVTAGTDRKVTYWDAYDGNAIRIIDGSDLDEVNALAVDRDGEALVSGGGDKLVKLWGYD-----EGHCYFVGVAHSGAITAVGVTPDKQRIVSVGTEGGIFIWDYQ 607          

Query:   37 IAAAHLKHVFGFRVGV-NGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSED-KPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVN---QISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWV-------SDERVILGTDTGKL--------ILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLY--SFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEE--AYSIALHPSGLYILVGFSDK---------LRLMNILIDDIRTFKEFSIRGCKEC--AFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLK--EISDSQVLREVE-SVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEY-LGHSAQITKMKITPNDDYLVTISDDCVVMIWR 1953
            +A   L  V GF   V  G   + +++ ++YP G  +++  I+ + Q F+ G    + ++ +AIS +  Y+A  + T    K  I+++D    + ++ L+   +   +  +++FSP+  YL       D  ++ W+  K   +      SPAA  +V     + F+          GN   +++   E +L N  I   E Q       V        D    LGT TG +        +L + G  + +F+L  S I     +     G+L        V S  G  V C                YK +++I +            Q  I +        + +V     H +Y  SFT     +         E + + F  +++            ATCA  + +R+W+  +N+ EL +        + I     G  I+  ++D           RLM + I++       +I    +C    S GG     V     QI   T  ++  +LK H   +  +    ++++ ++   DG    WD    +R  + +L +  +  +    +       GTD+ +   E+ D  V+RE+E S+   +  + ++  G     G N+  ++ + +     GE     +GHS  IT+++I+P + Y+V++S D  ++ W+
Sbjct:   11 VAELELDAVIGFNGHVPTGLKCHPDQEHMIYPLGCTVLIQAINTKEQNFLQG--HGNNVSCLAISRSGEYIASGQVTFMGFKADIILWD---YKNRELLARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICG----SPAAGLNVGNATNVIFSRCRDEMFMTAGNGTIRVW---ELDLPNRKIWPTECQTGQLKRIVMSIGVDDDDSFFYLGTTTGDILKMNPRTKLLTDVGPAKDKFSLGVSAI-----RCLKMGGLL--------VGSGAGLLVFC------------KSPGYKPIKKIQL------------QGGITSITLRGEGHQFLVGTEESH-IYRVSFTDFKETLIATCHFDAVEDIVFPFGTAELF-----------ATCA-KKDIRVWHTSSNR-ELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYV-INNAHRIGVTAIATTSDCKRVISGGGEGEVRVW----QIGCQTQ-KLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDLVRLRR-NQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDY---NEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRWK 615          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQG-----VLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKM-GDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGMESG 3636
            M+IA A  KH+FG + GV G I Y +EQT+VYP G+N ++YNIDQ+SQKFI G +KS  MTA+A+SPNRRYVA+AE    +KP I IYDL+S+RK+K LS+P++ +NEF S++FSPDSKYL  Q   PD+ L+YW WEKSK +A T+ ++P  +  V Q+SFNPQD+TQ+C +GN  FK FRYSE NLK F   K+E QN+LCH WVS+ERVI+GTDTG+L+L E GE++ EFN+ A    ++ +    N+G     +    QV+ IV+ SKGFA +CG G VH FEKTDDK+++KK REI IP D+NSADP K+Q Q+I  + +SPSEET+VA T++ QLY  TL S ++ K  GD ++FE+L+ SFHY QI GLD+C RKP+IAT + DRSVRIWNYE   LEL+KEFAEEAYSIALHPSGLYILVGFSDKLRLMN+LIDDIRTFKEF+IRGC+EC FS GG+ FAAVHSN+IQIYST+ FE   +LKGHNGK+R++VW++DD K++SCG DGAVYEW+T +GKR GESVLKSC YTG++VT DGK T+AVG+DKTLKEI+DSQ+LR++E+ D+ L++V LS+SGRMLF GT  G++ S KFPL  PGEW E+ GH +QITKMKI+ +D YLVT+S+D  V++W++QDKEGR +KRDK++GWAEEILITKSDLEEKN  M++L+TR DELK+EN+YQLRLKDMNYNEKIKELTEKFIQEME+LKTKNQVLKT+KDKEEAKHEE + E+M+KH+KELQD+ESANNQKLMLEYEK+QE Q+K+ +MQE+Y+R LQE E  K +A+EELTEYYETK  EK+T LE  + + R    EYEETK+ IEEDADREILD K  YE RLR E+E N +L+GE+GIMKKKF SLQ+EIDD KEEIKKFQ ETQK  NVIRN+EKD +GLKKEIQERD+TIQDKEKRIYDLKKKNQEL+KFKFVLDYKIKELKKQIEPRE +I+  K+QIQEMESELERFHKQN QL L+I EL QKL++T+KE+  ERQ  RDVEA V+RFKTDL+NCV YIQDPK LKESI ALY KH+QEDV      T  ASVDADIQKE++RQREHLERSVASLRKKLSKDSEIHRAD VRIMQENVSLIKEINDLR+ELK +RT  HDLEAA+GLH K+ +     +AA+TA  P  L+EK++EE  +++EMQ   I +LR +I  ++ G
Sbjct:    1 MSIAIAQAKHIFGLKPGVTGNICYHDEQTIVYPSGANCILYNIDQKSQKFIPGTDKSEGMTALAVSPNRRYVAIAEKG--EKPTITIYDLHSLRKRKVLSSPDVQSNEFVSLAFSPDSKYLVAQGGKPDYTLLYWTWEKSKVMAGTKTSNPQTSPPVYQVSFNPQDNTQLCVVGNGIFKHFRYSEGNLKTFNFQKMEPQNYLCHAWVSEERVIVGTDTGRLLLFEAGELKNEFNIGA----QQREAGRPNEGEEVSSIPVIPQVSAIVAYSKGFACSCGPGTVHLFEKTDDKDFFKKTREIKIPPDNNSADPTKAQQQLITCLTVSPSEETLVASTDLSQLYYLTLPSADLGKSEGDQAHFEVLAQSFHYGQITGLDVCIRKPLIATSSHDRSVRIWNYENCNLELHKEFAEEAYSIALHPSGLYILVGFSDKLRLMNLLIDDIRTFKEFTIRGCRECGFSNGGNLFAAVHSNVIQIYSTSTFENTSNLKGHNGKVRSIVWSSDDSKMVSCGGDGAVYEWETYSGKRVGESVLKSCGYTGVAVTPDGKATFAVGSDKTLKEIADSQILRQIEAGDMTLSSVALSHSGRMLFAGTVKGTLWSLKFPLNPPGEWTEHSGHGSQITKMKISYDDQYLVTVSEDASVILWKIQDKEGRGLKRDKEVGWAEEILITKSDLEEKNTMMSDLKTRNDELKLENDYQLRLKDMNYNEKIKELTEKFIQEMEALKTKNQVLKTDKDKEEAKHEEEMREVMDKHTKELQDLESANNQKLMLEYEKFQEQQSKTMKMQEEYDRLLQEKEESKMRAMEELTEYYETKLQEKTTQLEQAHDEARQSLKEYEETKKQIEEDADREILDIKNNYEIRLRAEKEDNIKLRGESGIMKKKFTSLQREIDDHKEEIKKFQAETQKQTNVIRNMEKDIMGLKKEIQERDDTIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPRENDIKRMKDQIQEMESELERFHKQNTQLELSIKELTQKLRATDKEMHQERQKVRDVEAVVKRFKTDLHNCVGYIQDPKMLKESIKALYSKHVQEDV------TESASVDADIQKEYSRQREHLERSVASLRKKLSKDSEIHRADNVRIMQENVSLIKEINDLRRELKIARTQIHDLEAAMGLHSKKNKNDTAAIAAITAKGPSALMEKDMEEKNKMIEMQMVEIRRLRSEISDLDFG 1196          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPA-ANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVD-SNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALG----LHRKQGEAARQ-LVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGME 3630
            M+IA A  +H+FG + GV+G I Y +EQT+VYP GSN ++YNIDQ+ Q+FI G +KS  MTA+A+SPNRRYVA+AE    ++P I IYDL+S+RKKK LS+ E+ ++E+ S++FSPDSKYL  Q   PDW L+YW WEKSK +A+ + ++P   N  V Q+SFNPQD+TQ+C +GN  F+ FRYSE NLK F   K+E QN+LCH WVS+ER+I+GTDTG+L+L E GE++ EFNL A  I ++A  L++    +  +QVT++VS SKGFA + GLG V+ FEKTDDK+Y+KK REI+IP D  NS D   +Q Q+I  + +SPSEET+VA T+  QLY  TLSS +++K GD + FE+LS  FH + I GLD+C RKP+IATC+VDRSVRIWNYET  LELYK FAEEAYSIALHPSGLYILVGFSDKLRLMN+LIDDIRTFKEF++RGC+ECAFS GGH FA+V  N+IQ+YSTT FE + +LKGHNGK+++VVW+ DD KL+SCGMDGAVYEWDT TGKR  ESV KSCSYTG+++T DGK T+AVG+DKTLKEI+DSQ+LREV + D+ L+TV+LS+SGRMLF GT  G++ S K+PL  PG+W E+ GH A I KMKI+ +D +LV+I++D  +++W++QDKEGR +KRDK++GWAEEILITKSDLEEKN T+ +L +RV+ELKMENEYQLRLKDM YNEK+KELTEKFIQEMESLKTKNQVLKT+KDKEE+KHEE + E+M+KH+KELQD+ESANNQKLMLEYEK+QE QAK  +MQEDY+RQLQE+E  KE+ALEELTEYYETK  + +T L+  N + R Q+ EYEETK+ IEEDADREILD K +YERRLR+E+E+N RL+GETGIMKKKF SLQKEIDD KEEIKK Q ET KL NVIR+LEKD +GLKKEIQERD+TIQDKEKRIYDLKKKNQEL+KFKFVLDYKIKELKKQIEPRE++I++ KEQIQEMESELERFHKQN QL LNI EL+QKLK+T+KE+  ERQ  RDVEA VRRFKTDL+NCV YIQDPK LKESI ALY+KH+QED+      T  ASVDADIQKEF+RQ+EHLERSVASLRKKL KDSEIH+AD VRIMQENV+LIKEINDLRKELK  R   HD+EAA+G      +  G+   Q  V A+   +  P+VEKELEE  +V+EMQ+  + +LRD+I  +E
Sbjct:    1 MSIAIAQARHIFGLKPGVSGNICYHDEQTIVYPAGSNCILYNIDQKVQRFIPGTDKSEGMTALAVSPNRRYVAIAEKG--ERPTITIYDLHSLRKKKVLSSHEVQSSEYISLAFSPDSKYLVAQGGKPDWTLLYWTWEKSKVMATAKTSNPQNPNSEVYQVSFNPQDNTQLCVVGNTVFRHFRYSEGNLKPFNFQKMEPQNYLCHAWVSEERIIVGTDTGRLLLFEAGEVKNEFNLVAPNI-DKAAALDDANTAMT-LQVTSLVSYSKGFACSFGLGTVYLFEKTDDKDYFKKAREIMIPPDLCNSQDSTLAQQQLIRCLAVSPSEETLVASTDQAQLYYLTLSSADLSK-GDQAQFEVLSQVFHNAPITGLDVCIRKPLIATCSVDRSVRIWNYETCNLELYKVFAEEAYSIALHPSGLYILVGFSDKLRLMNLLIDDIRTFKEFTVRGCRECAFSNGGHLFASVMGNVIQLYSTTTFENINNLKGHNGKVKSVVWSADDSKLVSCGMDGAVYEWDTFTGKRISESVWKSCSYTGVTITPDGKATFAVGSDKTLKEIADSQILREVPAGDMTLSTVSLSHSGRMLFAGTVKGTLWSLKYPLAVPGDWTEHQGHGAPIVKMKISFDDQFLVSIAEDASIILWKIQDKEGRGLKRDKEVGWAEEILITKSDLEEKNTTVNDLNSRVEELKMENEYQLRLKDMTYNEKMKELTEKFIQEMESLKTKNQVLKTDKDKEESKHEEEMAELMDKHAKELQDLESANNQKLMLEYEKFQEQQAKMMKMQEDYDRQLQEMEESKEKALEELTEYYETKIQDMTTKLDQSNDEARQQSREYEETKKQIEEDADREILDIKHQYERRLRDEKEANMRLRGETGIMKKKFTSLQKEIDDHKEEIKKLQAETSKLNNVIRSLEKDILGLKKEIQERDDTIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPREMDIKNMKEQIQEMESELERFHKQNTQLELNITELRQKLKATDKEMHQERQKVRDVEAVVRRFKTDLHNCVGYIQDPKMLKESIKALYQKHVQEDI------TESASVDADIQKEFSRQKEHLERSVASLRKKLEKDSEIHKADNVRIMQENVTLIKEINDLRKELKLCRVLIHDMEAAMGQDSRTRKMTGQGQGQGTVTALPTKQAGPMVEKELEEKSKVIEMQQLELRRLRDEIYDLE 1196          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPA-ANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDS-NSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKE----CAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLH-RKQGEAARQLVAAVT-ANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGMES 3633
            M+IA A  K++FG + GV+G I Y +EQT+VYP GSN ++YNIDQ++QKFI G EKS  MTA+A+SPNRRYVA+AE    +KP+I +YDL+S+RK+K LS+PE+   E+ S++FSPDSKYL  Q   PDW L+YW WEKSK +A+T+ ++P      VNQ+SFNPQD+TQ+C +GN  F+ FRYSE NLK F   K+E QN+LCH WV++ER+++GTD G+L++ E GE+++E  L          K + +   +++ Q+T IVS SKGFA ACG G V  FEKTDDK+++KK RE+ IP DS NSADP +   QII  + ISPSEET+VA T+  QLY  TLSS ++ + GD + FE+LS +FH  QILGLD+C RKP+IATC++DRSVRIWNYET  +EL+K FAEEAYSI+LHPSGLYILVGFSDKLRLMN+LIDDIRTFKEF+IRGC+E    CAFS GGH FAAVH N+IQIYSTT FE + +LKGHNGK+R+VVW+T+D +LISCGMDGAVY+WD  T KR GESVLK+CSYTG++VT DGK ++AVG+DKTLKEI+DSQVLREV S D+ LT V +S+SGRMLF GT  G++ S KFPLT PGEWQE+ GHSA ITKMKIT +D YL+T+++D  +++W++QDKEGR +KRDK++GWAEEILITKSDLEEKNA MA+L +RV+ELKMENEYQLRLKDMNYNEK+KELTEKFIQEMESLKTKNQVLKT+KDKEEAKHEE + E+MEKH+KELQD+ESANN KLMLEYEK+QE QAK  +MQEDY+RQLQE+E  KE+ALEELTEYYETK  E +T LE  N + R Q  EYEE K+ IEEDADREILD K KYERRLR+E+E+N RLKGETGIM+KKF SLQKEIDD KEEIKK Q ET KL N+IRNLEKD  GLKKEIQERD+TIQDKEKRIYDLKKKNQEL+KFKFVLDYKIKELKKQIEPRE +I++ KEQIQEMESELERFHKQN QL LNI EL+QKLK+ +KE++ ERQ  RDVEA VRRFKTDL+NCV YIQ+PK LKESI ALY+KH+QED++ T      ASVDADIQKEF RQ+EHLERSVASLRKKL KDSEIH+AD VRIMQENV LIKEINDLRKE+K  RT+ HDL+A LGL+ +KQ + +   +   + A + +  +E ++EE  R++++Q   I +LR+++  +ES
Sbjct:    1 MSIALAQAKYIFGLKPGVSGNICYHDEQTIVYPAGSNCILYNIDQKAQKFIPGSEKSDGMTALAVSPNRRYVAIAEKG--EKPIITVYDLHSLRKRKVLSSPEVPTGEYISLAFSPDSKYLIAQGGQPDWTLLYWTWEKSKVMATTKTSNPQNLGCDVNQVSFNPQDNTQLCVVGNTIFRHFRYSEGNLKPFSFQKLEPQNYLCHAWVTEERIVVGTDNGRLLIFEAGEMKSEIYLG---------KDDKDTEDISSNQITAIVSYSKGFACACGPGTVFLFEKTDDKDFFKKTREVKIPTDSYNSADPTEPLHQIITCLAISPSEETLVASTDQAQLYYLTLSSADLAR-GDQAIFEVLSQTFHNGQILGLDVCIRKPLIATCSLDRSVRIWNYETCNMELHKVFAEEAYSISLHPSGLYILVGFSDKLRLMNLLIDDIRTFKEFTIRGCREASLQCAFSNGGHLFAAVHGNVIQIYSTTTFECITNLKGHNGKVRSVVWSTNDSRLISCGMDGAVYDWDVATEKRIGESVLKTCSYTGVTVTPDGKTSFAVGSDKTLKEIADSQVLREVSSADMILTNVAMSHSGRMLFAGTVKGTLWSLKFPLTIPGEWQEHQGHSAAITKMKITLDDQYLITVAEDASILLWKIQDKEGRGLKRDKEVGWAEEILITKSDLEEKNALMADLNSRVEELKMENEYQLRLKDMNYNEKMKELTEKFIQEMESLKTKNQVLKTDKDKEEAKHEEEMAEVMEKHAKELQDLESANNHKLMLEYEKFQEQQAKMMKMQEDYDRQLQEMEESKERALEELTEYYETKLQEMTTKLEQSNDEARQQNREYEEMKKQIEEDADREILDIKNKYERRLRDEKEANMRLKGETGIMRKKFTSLQKEIDDHKEEIKKLQAETAKLNNIIRNLEKDIQGLKKEIQERDDTIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPRENDIKNMKEQIQEMESELERFHKQNTQLELNITELRQKLKACDKEMRLERQRVRDVEAIVRRFKTDLHNCVGYIQEPKMLKESIKALYQKHVQEDITET------ASVDADIQKEFGRQKEHLERSVASLRKKLEKDSEIHKADNVRIMQENVMLIKEINDLRKEVKLQRTHVHDLKATLGLYTKKQKKGSDHAIQMQSPARRHEATMELKMEEQNRLIDLQLMEIKRLRNEVQELES 1191          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAAN----FSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNV----QVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEA-ARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGMES 3633
            M+IA A  +H+FG + GV G +AYQ+EQT++YP GSN V+YNIDQ++QKFI G EKS  MTAMA+SPNR+YVA+AE    +K  I IYDL+S R++K LS+PE+ + E+ S++FSPDSKYL  Q   PDW L+YW W+KSK +AS + TS A        V Q++FNPQD+TQ+C +GN  FK++RYSE +LK F   K+E QN LC  WVSDERV++GTD G+L+L E GE++ EF++  S   ++ +    ++G         ++T IV+ SKGFA + G G V  +EKTDDKEY+KK REI IP DSNSADP KS+ Q+I  + +SPSEET+VA T+  QLYS TLSS ++ K G  + FE L  +FH  QI GLD+C RK ++ATC VDRSVRIWN+E   LELYKEFAEEAYSIALHPSGLY+LVGFSDKLRLMN+LIDDIR FKEF+IRGC+ECAFS GGH FAAV SNLI IYST  FE ++ LKGHNGKIR+V+WT DD KLISCGMDGAVYEWDT TGKR GE+VLKSCSY+ ++VT DGK T AVGTD TLKEISDS +LREV + D  L TV +S+SGRMLF GTN G++RS+KFPLT  GEWQEY GHS+ ITKMKIT +D  LVT+S+D  +M+W++QDKEGR  +RDK++GWAEEILITKSDLEEKN  MAEL+TRVDELK ENEYQLR+KDMNYNEKIKELTEKFIQEMESLKTKNQVLKT+KDKEEAKHEE + E +EKH+KE+QD+ESANNQKLMLEYEKYQ+L AKSQ+MQEDY+RQLQE+E  KE+ALEELTEYYET+  +K+T LE  +   R+   EYEETKR IEEDADREILD K +YER LR+E+ESN RLKGE+GIMKKKF SLQKEI+D KEEIKK  T+ +KL  VI NLEKDK GLKKEI ERDETIQDKEKRIYDLKKKNQEL+KFKFVLDYKIKELKKQIEPRE +I+  KEQIQEMESELERFHKQN QL LNI EL+QKLK+T+KE+  ERQ  RD EA ++RFKTDL+NCV YIQDPK LK+SI ALYKKH+QED+      T  ASVDADIQKE+ RQREHLERSVASLRKKL+KD+EIHRAD VRIMQENVSLIKEINDLRKELK +RT  HDLEAALGLHRK   A A   + AV +     ++EK+LEE+ R+++MQ+  I +LR  I  +E+
Sbjct:    1 MSIAVAQARHIFGLKTGVTGNVAYQDEQTIIYPSGSNCVLYNIDQKAQKFIPGSEKSTGMTAMAVSPNRKYVAIAEKG--EKATITIYDLHSQRRRKVLSSPEVQSGEYVSLAFSPDSKYLVAQGGKPDWTLLYWTWDKSKVMASIK-TSVAQGKEIPPPVYQVTFNPQDNTQLCVVGNQIFKLYRYSEGSLKPFAFQKMEPQNNLCQAWVSDERVVVGTDNGRLLLFEAGELKNEFHVEKSQKGDKEKMDSISEGEATQPSGPPEITAIVAYSKGFACSVGPGTVFLYEKTDDKEYFKKAREIKIPADSNSADPSKSENQVITSLTVSPSEETLVASTDSSQLYSMTLSSADLGKDG-QAYFEYLCQAFHQGQITGLDVCIRKALVATCGVDRSVRIWNFENCNLELYKEFAEEAYSIALHPSGLYVLVGFSDKLRLMNLLIDDIRVFKEFTIRGCRECAFSNGGHLFAAVTSNLIYIYSTATFENLLQLKGHNGKIRSVIWTADDNKLISCGMDGAVYEWDTFTGKRVGENVLKSCSYSSVAVTPDGKTTLAVGTDHTLKEISDSSILREVPAEDTTLNTVGMSHSGRMLFAGTNTGTLRSYKFPLTADGEWQEYQGHSSAITKMKITYDDTTLVTVSEDASIMLWKIQDKEGRGARRDKEVGWAEEILITKSDLEEKNTMMAELKTRVDELKTENEYQLRMKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTDKDKEEAKHEEEVQEALEKHAKEMQDMESANNQKLMLEYEKYQDLLAKSQKMQEDYDRQLQEMEDSKERALEELTEYYETELQKKTTQLEEAHDQARNAQKEYEETKRQIEEDADREILDIKNRYERLLRDEKESNLRLKGESGIMKKKFTSLQKEIEDHKEEIKKNHTDKEKLSGVISNLEKDKTGLKKEIAERDETIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPREKDIKDMKEQIQEMESELERFHKQNTQLELNITELRQKLKATDKEMHQERQKVRDREAMIKRFKTDLHNCVGYIQDPKMLKDSIKALYKKHVQEDI------TESASVDADIQKEYARQREHLERSVASLRKKLAKDTEIHRADNVRIMQENVSLIKEINDLRKELKIARTQVHDLEAALGLHRKNAAAEATATLQAVASQNKNAMLEKDLEESKRIVDMQKNEIKRLRLSIYELEN 1200          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPA-ANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDS-NSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGME 3630
            M+IA A  +++FG + GV G ++Y +EQT+VYP GSN ++YNIDQ++QKFI G ++S + TA+A+SPNRRYVALAE    +K +I IYDL+S+RKKK LS+ E+ +NE+ S++FSPDSKYL  Q   PDW L+YW WEKSK +AS + ++P   N  V Q+SFNPQD+TQ+C +GN  F+ FRYSE NLK F   K + QN+LCH WVS++R+I+GTD+GKL+L E GE++ EF LA + I  +    + +        VT++VS SKGFA + G G V+ +EKT+DKE++KK REI IP D  NS DP  +Q Q+   + +SPSEET++  T+  QLY  TLSS +++K GD ++FE+LS  FH + ILGLD+C RKP+IATC++DRSV+IWNYET  LELYK FAEEAYS+ALHPSGLYILVGFSDKLRLMN+LIDDIRTFKEF++RGC+ECAFS GGH FA+V  N+IQ+YSTT FE + +LKGHNGK++ VVW+ DD KLISCGMDGAVYEWDT +GKR  ESV+KSC+YT ++VT DGK T+AVGTDK LKEI+DS +LREV + D+ L+TV +S+SGRMLF GT  G++ S KFPL  PG+W EY GH A I KMKIT +D YL+++++D  +++W++QDKEGR +KRDK++GWAEEILITKSDLEEKN+T+A+L +RV+ELKMENEYQLRLKDM YNEK+KELTEKFIQEMESLKTKNQVLKT+KDKEEAKHEE L E+M+ H+KE+QD+ESANNQKLMLEYEK+QE QAK  +MQEDY++QLQE+E  KE+ALEELTEYYETK  E +  LE  N + R Q  EYEETK+ IEED DREILD K +YERRLR+E+E+N RLKGETGIMKKKF SLQKEIDD K+EIKK Q E  KL NVIR+LEKD  GLKKEIQERD+TIQDKEKRIYDLKKKNQEL+KFKFVLDYKIKELKKQIEPRE++I++ KEQIQEMESELERFHKQN QL LNI EL+QKLK+T+KE+  ERQ  RDVEA VRRFKTDL+NCV YIQDPK LKESI ALY+KH+QED+     +T  ASVDADIQKEF+RQ+EHLERSVASLRKKL KDSEIH+AD VRIMQENV+LIKEINDLRKEL+  R   HD+EAA+GL  + G+    +   +      PLVEKELEE  +++EMQ+  + +LRD+I  ME
Sbjct:    1 MSIAIAQARYIFGLKSGVTGNVSYHDEQTIVYPAGSNCILYNIDQKTQKFIQGTDRSEETTALAVSPNRRYVALAEKG--EKAIITIYDLHSLRKKKVLSSSEVQSNEYVSLAFSPDSKYLVAQGGKPDWTLLYWTWEKSKVMASIKTSNPQNPNSEVYQVSFNPQDNTQLCVVGNTVFRYFRYSEGNLKPFNFQKSDPQNYLCHAWVSEDRIIVGTDSGKLLLFEAGELKREFILANNDISTDESSYQTH--------VTSLVSYSKGFACSFGYGTVYLYEKTEDKEFFKKSREITIPPDPYNSQDPALNQQQLFRHLTVSPSEETLIGSTDQSQLYYLTLSSADLSK-GDQASFEILSQVFHNAPILGLDVCIRKPLIATCSMDRSVKIWNYETCNLELYKVFAEEAYSVALHPSGLYILVGFSDKLRLMNLLIDDIRTFKEFTVRGCRECAFSNGGHLFASVMGNVIQLYSTTTFENINNLKGHNGKVKAVVWSADDSKLISCGMDGAVYEWDTFSGKRISESVMKSCNYTSVTVTPDGKTTFAVGTDKALKEIADSHILREVMAGDMTLSTVAMSHSGRMLFAGTVKGALWSMKFPLAVPGDWTEYPGHGAAIVKMKITFDDQYLISVAEDATIILWKIQDKEGRGLKRDKEVGWAEEILITKSDLEEKNSTVADLNSRVEELKMENEYQLRLKDMTYNEKMKELTEKFIQEMESLKTKNQVLKTDKDKEEAKHEEELSEIMDNHAKEIQDLESANNQKLMLEYEKFQEQQAKMMKMQEDYDKQLQEMEDSKEKALEELTEYYETKLQEMTAKLEQCNDETRQQNREYEETKKQIEEDGDREILDIKHQYERRLRDEKEANMRLKGETGIMKKKFTSLQKEIDDHKDEIKKLQAEALKLNNVIRSLEKDIQGLKKEIQERDDTIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPREMDIKNMKEQIQEMESELERFHKQNTQLELNITELRQKLKATDKEMHQERQKVRDVEAIVRRFKTDLHNCVGYIQDPKMLKESIKALYQKHVQEDI-----KTESASVDADIQKEFSRQKEHLERSVASLRKKLEKDSEIHKADNVRIMQENVTLIKEINDLRKELRICRVLIHDMEAAMGLDVR-GQKKTGITIPLPPKPVGPLVEKELEEHKKIIEMQQLELKRLRDEIYDME 1185          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLN--SMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQL-YSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQE-DVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKI 3618
            MA   A   H+FG R GVN  + + +E T+V+PCG+N V Y++DQ  Q FI G E+S  M AMAIS NRRY+A+AE   ++K  I IYDL     R++K L+  E+   EF  ++FSPDSKYL GQ  GP+W L YW WEK K +A+ + TS   +      SF PQD+ QIC  GN  FK+FRY+E  LK    +K+E  N L H W+S ER+I GT+TG+L++ E+G+ R   ++ +    +E +  + +       +VT I   SKGFA + G G V  FEKT++K+ YKK REI IP D    DP +++ Q I+ +CISPSEET+ A T+  Q  Y   L  T +                     LG        ++  C+              LELYKEF EE+YS+ALHPSGL+ILVGFSDK+RLMN+LIDDIR FKEF++RGC+ECAFS+GGH FAAV+ N+I IYSTT FE V++LKGHNGK+R++ W+ DD +L+SCGMDGAVYEW+  +GKR  ESVLK+CSYTG++++ D K  +AVG+D TLKEI D Q+LRE+ S D   TT+ +++SGR LF GT  G++R+ K+PL    +W EY  HSA ITKM +T +D +L+T+S+D  ++IW++ DKEGR++KR+K++ +AEEILITKSDLEEKN  M EL+TRVDELKMENEYQLRLKDMNYNEKI+ELTE+FIQ++ESLKT+NQVLKTEK+K+   H+E           +L   ES NNQKLMLEY+KY ELQ KSQ+MQE YE +LQ+LE  K  ALE+LT++YE K  EK + L     + R Q  E+EET +L EED DRE+ D +I+YE +LR+E+E+N + + E  +MKKK  SLQ+E+ ++  EI K + E  KLE +I++LEKD + LK+E+Q+RD TI DKEK IYDL  KNQEL+KFKFVLDYKI ELKKQIEPRE  I+  KEQ QEME EL +F ++N QL L I +LK KLK+T+KE+  E Q  R+VEA VRR KTDL+NCV +IQ+PK LK+SI  LY++++Q+ DV           VDADIQ+E +RQ+EHLER+VASL++KLS D+ +H+A  V+ M+EN  LIKEINDLRKEL+  R   H+ E   GL +K    +  L  ++          K  EEA R+++ QR  I +LR ++
Sbjct:    1 MAAVVAQSHHIFGLRTGVNNNLLFFDEHTVVFPCGNNCVRYDLDQACQSFIPGTERSQSMQAMAISANRRYLAVAE--HKEKATITIYDLQHEQSRRRKVLTGGELPVREFVCMAFSPDSKYLIGQAGGPEWTLFYWVWEKHKIMATVKTTSTGPS-----TSFCPQDNMQICVSGNGLFKIFRYTEGALKQTNSVKMEQHNILSHAWMSKERIIAGTETGRLLVFESGDQRGSLSVTSKPSTQERKSEDTSSSPALLPRVTAISPYSKGFACSAGPGTVCLFEKTEEKDSYKKNREIKIPPDPCFNDPTQAEQQEISTLCISPSEETLAASTDRGQSNYPTPLCFTAV--------------------FLGSKYALSGGVLVCCSA-------------LELYKEFQEESYSVALHPSGLFILVGFSDKIRLMNLLIDDIRAFKEFTVRGCRECAFSHGGHMFAAVNGNVIHIYSTTTFENVLNLKGHNGKVRSMAWSADDSRLVSCGMDGAVYEWNALSGKRESESVLKTCSYTGLTLSPDNKTIFAVGSDCTLKEIQDCQILREMASDDAAYTTIAMTHSGRALFTGTAFGTVRAIKYPLPLQKDWTEYQAHSAPITKMVVTFDDQFLLTVSEDGCLLIWKIIDKEGRALKREKEMSYAEEILITKSDLEEKNQFMLELKTRVDELKMENEYQLRLKDMNYNEKIRELTEEFIQQIESLKTENQVLKTEKEKQAVTHKE-----------DLTFAESNNNQKLMLEYDKYHELQLKSQQMQESYEEKLQQLEDSKVHALEKLTQFYEAKIQEKVSALGQCQDETRQQLREFEETIKLTEEDGDRELQDIRIRYENKLRKEKETNIKHEDEIRVMKKKHDSLQRELKNKDLEIDKLKLEQNKLEGIIKSLEKDILVLKREVQKRDVTINDKEKNIYDLNSKNQELEKFKFVLDYKITELKKQIEPRENVIKEMKEQTQEMEGELAQFQQKNTQLELTIADLKLKLKATDKEMHKEMQRVRNVEALVRRIKTDLHNCVGFIQEPKKLKDSIRTLYERYVQQSDV------VEIVGVDADIQRENSRQKEHLERNVASLKRKLSNDTNVHQAYKVKTMKENAFLIKEINDLRKELRLIRAQLHNYETQEGLSKKNKCKSEVLSPSL----------KFEEEAERIIQFQRVEIQRLRQEL 1133          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLN--SMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELY-KEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQE-DVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTAN-KPQPLVEKEL---EEAGRVMEMQRALIGQLRDKI 3618
            MA   A   H+FG R GVN  + + +E T+V+PCG+N V Y++DQ  Q FI G E+S  M AMAIS NRRY+A+AE   ++K  I IYDL     R++K L+  E+   EF  ++FSPDSKYL GQ  GP+W L YW WEK K +A+ + TS      ++Q+SF PQD+ QIC  GN  FK+FRY+E  LK    +K+E  N L H W+S ER+I GT+TG+L++ E+G+ R   ++ +    +E +  + +       +VT I   SKGFA + G G V  FEKT++K+          P D    DP +++ Q I+ +CISPSEET+ A T+  QLY  TLSS E+++ G+ + FE LS+SFH   I GL +C RKP+IATC++D SVRIWN+ETN  E Y KEF EE+YS+ALHPSGL+ILVGFSDK+RLMN+LIDDIR FKEF++RGC+ECAFS+GGH FAAV+ N+I IYSTT FE V++LKGHNGK+R++ W+ + +      MDGAVYEW+  +GKR  ESV                       D TLKEI D Q+LRE+ S D   TT+ +++SGR LF GT  G++R+ K+PL    +W EY            T +   +VT  D   ++        GR         +AEEILITKSDLEEKN  M EL+TRVDELKMENEYQLRLKDMNYNEKI+ELTE+FIQ++ESLKT+NQVLKTEK+K+   H+E L E+++KH KE QD+ES NNQKLMLEY+KY ELQ KSQ+MQE YE +LQ+LE  K  ALE+LT++YE K  EK + L     + R Q  E+EET +L EED DRE+ D +I+YE +LR+E+E+N + + E  +MKKK  SLQ+E+ ++  EI K + E  KLE +I++LEKD + LK+E+Q+RD TI DKEK IYDL  KNQEL+KFKFVLDYKI ELKKQIEPRE  I+  KEQ QEME EL +F ++N QL L I +LK KLK+T+KE+  E Q  R+VEA VRR KTDL+NCV +IQ+PK LK+SI  LY++++Q+ DV           VDADIQ+E +RQ+EHLER+VASL++KLS D+ +H+A  V+ M+EN  LIKEINDLRKEL+  R   H+ E   GL +K      +  +A   N KP+      L   EEA R+++ QR  I +LR ++
Sbjct:    1 MAAVVAQSHHIFGLRTGVNNNLLFFDEHTVVFPCGNNCVRYDLDQACQSFIPGTERSQSMQAMAISANRRYLAVAE--HKEKATITIYDLQHEQSRRRKVLTGGELPVREFVCMAFSPDSKYLIGQAGGPEWTLFYWVWEKHKIMATVKTTSTGP---IHQVSFCPQDNMQICVSGNGLFKIFRYTEGALKQTNSVKMEQHNILSHAWMSKERIIAGTETGRLLVFESGDQRGSLSVTSKPSTQERKSEDTSSSPALLPRVTAISPYSKGFACSAGPGTVCLFEKTEEKDN---------PPDPCFNDPTQAEQQEISTLCISPSEETLAASTDRGQLYHITLSSVEMSR-GEQAQFEFLSHSFHSGIITGLSICMRKPLIATCSLDHSVRIWNFETNAREHYVKEFQEESYSVALHPSGLFILVGFSDKIRLMNLLIDDIRAFKEFTVRGCRECAFSHGGHMFAAVNGNVIHIYSTTTFENVLNLKGHNGKVRSMAWSAERQSAGLLWMDGAVYEWNALSGKRESESV-----------------------DCTLKEIQDCQILREMASDDAAYTTIAMTHSGRALFTGTAFGTVRAIKYPLPLQKDWTEYQAPFC-------TYHQSMVVTFDDQFFLL----DGFRGRV--------YAEEILITKSDLEEKNQFMLELKTRVDELKMENEYQLRLKDMNYNEKIRELTEEFIQQIESLKTENQVLKTEKEKQAVTHKEALSEVLKKHGKEQQDLESNNNQKLMLEYDKYHELQLKSQQMQESYEEKLQQLEDSKVHALEKLTQFYEAKIQEKVSALGQCQDETRQQLREFEETIKLTEEDGDRELQDIRIRYENKLRKEKETNIKHEDEIRVMKKKHDSLQRELKNKDLEIDKLKLEQNKLEGIIKSLEKDILVLKREVQKRDVTINDKEKNIYDLNSKNQELEKFKFVLDYKITELKKQIEPRENVIKEMKEQTQEMEGELAQFQQKNTQLELTIADLKLKLKATDKEMHKEMQRVRNVEALVRRIKTDLHNCVGFIQEPKKLKDSIRTLYERYVQQSDV------VEIVGVDADIQRENSRQKEHLERNVASLKRKLSNDTNVHQAYKVKTMKENAFLIKEINDLRKELRLIRAQLHNYETQEGLSKKN-----KCKSATNINSKPESGSIWSLKFEEEAERIIQFQRVEIQRLRQEL 1136          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLN--SMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELER 2985
            MA   A   H+FG R GVN  + + +E T+V+PCG+N V Y++DQ  Q FI G E+S  M AMAIS NRRY+A+AE   ++K  I IYDL     R++K L+  E+   EF  ++FSPDSKYL GQ  GP+W L YW WEK K +A+ + TS   +      SF PQD+ QIC  GN  FK+FRY+E  LK    +K+E  N L H W+S ER+I GT+TG+L++ E+G+ R   ++ +    +E  +  ++   L   +VT I   SKGFA + G G V  FEKT++K+ YKK REI IP D    DP +++ Q I+ +CISPSEET+ A T+  QLY  TLSS E+++ G    FE LS+SFH   I GL +C RKP+IATC++D SVRIWN+ETN LELYKEF EE+YS+ALHPSGL+ILVGFSDK+RLMN+LIDDIR FKEF++RGC+ECAFS+GGH FAAV+ N+I IYSTT FE V++LKGHNGK+R++ W+ DD +L+SCGMDGAVYEW+  +GKR  ESVLK+CSYTG++++ D K  +AVG+D TLKEI D Q+LRE+ S D   TT+ +++SGR LF GT  G++R+ K+PL    +W EY  HSA ITKM +T +D +L+T+S+D  ++IW++ DKEGR++KR+K++ +AEEILITKSDLEEKN  M EL+TRVDELKMENEYQLRLKDMNYNEKI+ELTE+FIQ++ESLKT+NQVLKTEK+K+   H+E           +L   ES NNQKLMLEY+KY ELQ KSQ+MQE YE +LQ+LE  K  ALE+LT++YE K  EK + L     + R Q  E+EET +L EED DRE+ D +I+YE +LR+E+E+N + + E  +MKKK  SLQ+E+ ++  EI K + E  KLE +I++LEKD + LK+E+Q+RD TI DKEK IYDL  KNQEL+KFKFVLDYKI ELKKQIEPRE  I+  KEQ QE+   ++R
Sbjct:    1 MAAVVAQSHHIFGLRTGVNNNLLFFDEHTVVFPCGNNCVRYDLDQACQSFIPGTERSQSMQAMAISANRRYLAVAE--HKEKATITIYDLQHEQSRRRKVLTGGELPVREFVCMAFSPDSKYLIGQAGGPEWTLFYWVWEKHKIMATVKTTSTGPS-----TSFCPQDNMQICVSGNGLFKIFRYTEGALKQTNSVKMEQHNILSHAWMSKERIIAGTETGRLLVFESGDQRGSLSVTSKPSTQEKSEDTSSSPALLP-RVTAISPYSKGFACSAGPGTVCLFEKTEEKDSYKKNREIKIPPDPCFNDPTQAEQQEISTLCISPSEETLAASTDRGQLYHITLSSVEMSRFG-RCQFEFLSHSFHSGIITGLSICMRKPLIATCSLDHSVRIWNFETNALELYKEFQEESYSVALHPSGLFILVGFSDKIRLMNLLIDDIRAFKEFTVRGCRECAFSHGGHMFAAVNGNVIHIYSTTTFENVLNLKGHNGKVRSMAWSADDSRLVSCGMDGAVYEWNALSGKRESESVLKTCSYTGLTLSPDNKTIFAVGSDCTLKEIQDCQILREMASDDAAYTTIAMTHSGRALFTGTAFGTVRAIKYPLPLQKDWTEYQAHSAPITKMVVTFDDQFLLTVSEDGCLLIWKIIDKEGRALKREKEMSYAEEILITKSDLEEKNQFMLELKTRVDELKMENEYQLRLKDMNYNEKIRELTEEFIQQIESLKTENQVLKTEKEKQAVTHKE-----------DLTFAESNNNQKLMLEYDKYHELQLKSQQMQESYEEKLQQLEDSKVHALEKLTQFYEAKIQEKVSALGQCQDETRQQLREFEETIKLTEEDGDRELQDIRIRYENKLRKEKETNIKHEDEIRVMKKKHDSLQRELKNKDLEIDKLKLEQNKLEGIIKSLEKDILVLKREVQKRDVTINDKEKNIYDLNSKNQELEKFKFVLDYKITELKKQIEPRENVIKEMKEQTQEVGFSVQR 967          

Query:  121 VYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVA---LAETTSEDK---PVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDS--KYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNL-KNFGIL-KVESQNF-LCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSS--TEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGF-SDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFA-AVHSNLIQIYSTT----NFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRC----------GESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKP-GEWQEYLGHSAQITKMKITPNDDYLV-TISDDCVVMIWRV 1956
            +Y   S +V+YN+D++ Q+  +G   +  +  +A+ P++  +A   +A T+S+ K   P + ++D  S+     L +          +SFS  +   +L       D +L  W W++ ++LA  +     +N SV    F+P D+  I   G +    +   +N+L K  G+  K E   F LC T+  +   I G  +G +++   G  R       SL ++ A   E++   L  ++  T++S  K   +    G             Y+K++ + IP       P ++ A+           ET++  T  + +   +L    T IT+              H  ++ GL +   K    TC  D+ V +W+ + +Q    K   + A S   HPSG  + +G  + +  +++    D+ T            +FS  G++ A   H N I IY+ +     +  V    GH+  I ++ W+ D + L+S   D  +  W  +  K+             S   + S+    +  DG +    GTD                     +  V  SN  R+L  G + G +  F FP ++       Y GHS+ +T +    ND +LV T   D  VM WRV
Sbjct:  165 LYFIASVVVLYNVDEQLQRHYTG--HTDDIKCLAVHPDKITIATGQVAGTSSDGKQLAPHVRVWDSVSLNTLHVLGS-GFFDRALVCLSFSKSNGGSWLCVVDDSNDHVLSVWDWQREERLAEVK----CSNESVFATDFHPTDANTIVTCGKSHLYFWSLEKNSLVKKQGLFEKQEKPKFVLCVTFSENGDAITGDSSGNILVWGKGSNRI------SLAVQAAH--ESSVLALCMLRNGTLLSGGKDRRITAWDGN------------YQKIQTVEIP---EVYGPIRTVAE--------GRGETVLIGTTKNYVLQGSLDGEFTPITQG-------------HTDELWGLAVHPLKHQFLTCGHDKLVCLWDCDQHQPLWTKTMEDAAQSAGFHPSGATVAIGTQTGRWLVLDTETKDLVTMHTDGNEQISVMSFSPDGNFLAIGSHDNYIYIYAVSENGRKYSRVGKCSGHSSFITHLDWSVDSQYLVSNSGDYEILYWIPSVCKQVVSVETTRDIPWSSFTCTLSFHVFGLWPDGSD----GTD---------------------VNAVCRSNETRLLATGDDFGKVHLFSFPCSQSRAPSHMYGGHSSHVTNVHFLFNDSHLVSTGGKDMSVMQWRV 731          

Query:  121 VYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVA---LAETTSEDK---PVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDS--KYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNL-KNFGIL-KVESQNF-LCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSS--TEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGF-SDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFA-AVHSNLIQIYSTT----NFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRC----------GESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKP-GEWQEYLGHSAQITKMKITPNDDYLV-TISDDCVVMIWRV 1956
            +Y   S +V+YN+D++ Q+  +G   +  +  +A+ P++  +A   +A T+S+ K   P + ++D  S+     L +          +SFS  +   +L       D +L  W W++ ++LA  +     +N SV    F+P D+  I   G +    +   +N+L K  G+  K E   F LC T+  +   I G  +G +++   G  R       SL ++ A   E++   L  ++  T++S  K   +    G     +  +  E Y  +R +           G+               ET++  T  + +   +L    T IT+              H  ++ GL +   K    TC  D+ V +W+ + +Q    K   + A S   HPSG  + +G  + +  +++    D+ T            +FS  G++ A   H N I IY+ +     +  V    GH+  I ++ W+ D + L+S   D  +  W  +  K+             S   + S+    +  DG +    GTD                     +  V  SN  R+L  G + G +  F FP ++       Y GHS+ +T +    ND +LV T   D  VM WRV
Sbjct:  264 LYFIASVVVLYNVDEQLQRHYTG--HTDDIKCLAVHPDKITIATGQVAGTSSDGKQLAPHVRVWDSVSLNTLHVLGS-GFFDRALVCLSFSKSNGGSWLCVVDDSNDHVLSVWDWQREERLAEVK----CSNESVFATDFHPTDANTIVTCGKSHLYFWSLEKNSLVKKQGLFEKQEKPKFVLCVTFSENGDAITGDSSGNILVWGKGSNRI------SLAVQAAH--ESSVLALCMLRNGTLLSGGKDRRITAWDGNYQKIQTVEIPEVYGPIRTVA---------EGRG--------------ETVLIGTTKNYVLQGSLDGEFTPITQG-------------HTDELWGLAVHPLKHQFLTCGHDKLVCLWDCDQHQPLWTKTMEDAAQSAGFHPSGATVAIGTQTGRWLVLDTETKDLVTMHTDGNEQISVMSFSPDGNFLAIGSHDNYIYIYAVSENGRKYSRVGKCSGHSSFITHLDWSVDSQYLVSNSGDYEILYWIPSVCKQVVSVETTRDIPWSSFTCTLSFHVFGLWPDGSD----GTD---------------------VNAVCRSNETRLLATGDDFGKVHLFSFPCSQSRAPSHMYGGHSSHVTNVHFLFNDSHLVSTGGKDMSVMQWRV 830          

Query: 1042 SFTLSSTE--ITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFS--IRGCKECAF----SYGGHYFAAVHSNLIQIYSTT----NFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEW-DTNTGKRCGESVLKSCSYTGISVTQDGKNTYAV---GTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKP-GEWQEYLGHSAQITKMKITPNDDYLVTISD-DCVVMIWRVQ 1959
            SF + +TE  I +   H  F  +    H  ++ GL + + +    TCA D+   +WN  T++    K   +   S   HPSG  + +G     +  + L+ D++T KE      G ++ A       G H     + N I +YS +     +  V    GH+  + ++ W+T+ + L+S   D     W   N  +    + ++   +  ++    G +T+ V   G D T                   +  +  S SG++   G + G +R F+    +P      Y GH + +T +  + +D ++ T    D  V+ WRVQ
Sbjct:  349 SFWVGTTENGILQGSAHGEFSPVVQG-HTDELWGLAVHQNQDAFLTCAQDKQAILWNSATHRPTWIKTLKDPLQSADFHPSGKVVAIG----TQAASWLVLDLKTQKELHHESAGNEQIAVMRYSPDGSHLAVGSNDNFIYVYSVSEEGHKYNAVGKCTGHSSFVTHLDWSTNGEFLMSNSGDYETLYWTPANCKQVTAMATVRDVEWATMTCVL-GFSTFGVWSEGADGT------------------DINALCRSGSGKLCVLGDDFGKVRLFRSSAFQPRSPSHAYGGHCSHVTNVAFSSDDSFVFTTGGKDMGVLQWRVQ 648          

Query:   52 LKHVFGFRVGV-NGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSED-KPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQN------FLCHTWVSDERVI-LGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNN---VQVTTIVSSSKG-FAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLS--STEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEE--AYSIALHPSGLYILVGFSD---------KLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLK--EISDSQVLREVE-SVDVQLTTVTLSNSGRMLFC--GTNNGSIRSFKF---PLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWR 1953
            L+ V GF   V +G +++ + + L+YP G  +V+ ++    Q F+ G   ++ ++ +A+S +  YVA  + T    K  +++++         L+  ++   +  +++FSP+  YLA      D  ++ W   K + +    ++ P A  + N + F           GN+  ++++    ++ N  I   + Q         C     D+     GT +G ++ V         NL          KL N+ G   N   + VT +     G   V  G G V   ++ + K   K   E                   +  + +        A T + Q+Y F L   + E+           +++ F  S            + ATC+  + +R+W+ ++ + EL +        +SI    +G  I+ G++D           RLM I ID+       ++    +C     G     V    +    T +  +V ++K H   I  +    +DK+ +S   DG    WD     R  + V+ +  +       +       GTD+ +   E+ D  ++RE+E S    +  + +S  G       G ++  I+ + +    +T  G+     GHS  +T++ + PN  +++++S D  ++ WR
Sbjct:   16 LESVIGFNGQVPSGLVSHPDCEHLLYPLGCTVVIRSLKGARQSFLHG--HTNNVSCLAVSNSGHYVASGQVTYMGFKADVILWNFEKRELHARLTLHKV---KVEALAFSPNDLYLASLGGQDDGSVVIWNVTKKEAVCGNAVSLPTAG-TTNTVRFTNTSDLSFITAGNDTIRVWQL---DIPNRKIRPTDCQTGQLKRIIKCVAVAPDDSFFYCGTTSGDILKV---------NLKT--------KLLNSYGPAKNKLTLGVTALSLLKSGELLVGTGDGVVALCKEANFKTMQKVALE-----------------GAVTSISLRGQGHQFFAGTAVAQIYQFNLPEFTHEMIATCHSEPVNDVAFPFITSGT--------SELFATCS-SQDIRVWHTQSGK-ELLRITVPNMTCHSIQFARNGKNIVSGWNDGKIRAFTPESGRLMYI-IDNAHGMGVTTVSLTGDCKRIISGGVSGQVR---VWELGTQSQRLVEAMKEHKSSISCIRLKHNDKECVSASTDGTCIIWDLERFVR-KQIVMANTLFKCACYHPEEFQIITSGTDRKIGFWEVFDGSLIRELEASQSGSINGMDVSPDGEYFVTVKGGDDKLIKVWSYNDGDVTFVGK-----GHSGNVTRLCVCPNRWHILSVSTDGAILRWR 620          

Query: 1117 HYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFA--EEAYSIALHPSGLYILVGFSDK-LRLMNILIDDIRTFKEFSIRGCKECAFSYGGH---YFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWD----------------------TNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKE---GRSVKRD 1989
            H   +      R    +A+CA D  ++ WN  T + EL   +A  E     A  P+G  I  G +D  ++L N     +           + C F++  H          + I+++         +L GH+G +R   ++ DD++L+SC +D  +  W                       T  G+R     L+SC++     + DG+   AV  +      + +     V       T + ++ +   L C     S     + +    +  +Y GH   +  +  + +  +L++ S+D  V +W+V  +E   G  +KRD
Sbjct:  120 HAGAVYHAAFSRSGEYVASCAGDGYLKKWNSRTGE-ELMATYAHDEPVLCCAFAPNGRVIATGSADHTVKLWNAQSGRLLGPHRAHDGEVQHCTFAHAFHKPLLATCSQDSSIKLWEWKEQGKGSALLGHSGPVRCCCFSPDDQRLVSCSVDCTLKVWSVKLRQEERSVDVRECVDSEDGATKEGER--SLALRSCAW-----SPDGRRIVAVAENIVFVFNALTVACENVLRTHAHCTILAVAFAPDSLHCAVGLSSYSLEMWNVKSCRKTADYRGHVGWVHGVAFSADGSWLLSASEDHTVSLWQVNGEESAAGVYLKRD 433          

Query: 1117 HYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFA--EEAYSIALHPSGLYILVGFSDK-LRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFA-AVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTG-ISVTQDGKNTYAVGTDKTLK--EISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWR 1953
            H   I  +D       +A+ ++D  + +WN++  Q   Y+     +   S+   PSG  ++    DK +RL    +    T  +      +  +FS  G     A     I++++    + + SL  H+  +R+  ++ D + ++S   D  V  WD+N+ + C  +  +   +   +     G    A GTD T+K  +I  +++L+  +     + +++   +G  L   +N+ +++     L +   +    GH    T +  +   D+  +   D  VM+W+
Sbjct:   17 HRDTITSVDFNPNMKQLASGSMDACLMVWNFKP-QTRAYRFVGHKDAVMSVQFSPSGHLVVSASRDKTVRLWVPSVKGESTVFKAHTATVRSVSFSADGQSLVTASDDKSIKVWTVHRQKFLYSLNQHSNWVRSAKFSPDGRLIVSGSDDRTVRVWDSNS-RECVHTFYEHGGFVNQVDFHPSGTCIAAAGTDNTVKVWDIRMNKLLQHYQVHGAAVNSLSFHPTGNYLITASNDSTLKVLD--LVEGRLFYTLHGHQGPATAVAFSRAGDFFASGGSDEQVMVWK 298          

Query:   52 LKHVFGFRVGVNGAIAYQNEQTLV-YPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMF-----RYSENNLK-----NFGILKVESQNFLC 639
            L+ V G  +  +  +    +  LV YP G  +V++N  +  Q  I    +   +T +A SP+ +Y+   E  S   P + ++DL     +  +S  +      + ++FSP+ KY+       D ++  W W K   +A  +++S      V  +SF+  D++    +GN   + +     + S+ NL        G+L V+  NF C
Sbjct:    3 LEKVLGITLSSSSGLCCDPKTGLVAYPAGCTVVIFNPKKGKQTHIFNASRK-PITTLAFSPDGKYLVTGE--SGHMPAVRVWDLAD---RTQVSEFQRHKYGISCVAFSPNVKYVVSVGYQHDMMVNVWDWRKGALIAFNKVSS-----KVTAVSFS-SDNSYFVTVGNRHVRFWYLDASKASKANLTVPLLGRSGLLGVQRNNFFC 197          

Query: 1378 KECAFSYGGHYFA-AVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQ-DGKNTYAVGTDKTLKEISDSQVLREVESVDVQ----------LTTVTLSNSGRMLFCGTNNGSIRSF-----------KFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIW 1950
            +   FS  G + A      LI+I+   N ++VM L+GH   I ++ +     KL+S   D  V  WD  TG+ C  ++      T ++V+  DGK   A   D+ ++ + DS+    VE +D +          + +V  +  G+ +  G+ + S++ +           K P +   E   Y+GH   +  +  T ND+Y+++ S D  V+ W
Sbjct:  447 RSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQ-CSLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVR-VWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVT-YIGHKDFVLSVATTQNDEYILSGSKDRGVLFW 657          

Query: 1117 HYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGK 1590
            H   I  L +     I AT + D++ +IWN E  +LE          ++A H  GL+                 D+ +F ++     K  A S G           ++I+S   F V+ +L+GH   ++   +    K+LISCG DG +  WD ++G+
Sbjct:  490 HEKDINALSVSPNDSIFATASYDKTCKIWNLENGELE---------ATLANHKRGLW-----------------DV-SFCQYD----KLLATSSG--------DKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCSSGE 608          

Query: 1417 AVHSNLIQIYS--TTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNT---------GKRCGESVLKSCSYTGISVTQDGK-NTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFP------LTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQD 1962
            A H N +++Y   TTN   V S +GH G + +V +  D++ +++   DG +  WD  +              E V+       IS  +DG    + +G ++   +++           D  L ++++++ G ML      G+   ++ P        KP    ++  HS  IT++ ++ +  +L T S D    +W + D
Sbjct:   50 AGHQN-VRLYDIRTTNPNPVASFEGHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVRSPSIPRNYKHNAPVNEVVIHPNQGELISCDRDGNIRIWDLGENQCTHQLTPED--------DTSLQSLSMASDGSMLAAANTKGNCYVWEMPNHTDASHLKPV--TKFRAHSTYITRILLSSDVKHLATCSADHTARVWSIDD 238          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNL---------AASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKK 2661
            M+IA A  +H FG +                              +SQ+FI G +KS  MTAMA+SPNRRYVA+AE    +K  I IYDL+++RKKK LS PE+ + EF S++FSPDSKYL  Q+  PDW L+YW WEK+K +A T+ +S   + +V Q+SFNPQD+TQ+C +GN  FK+FRYSE NLK F   K+E QNFLCH WVSDER+I GTDTG+L+L E+GE++ EF++          A  +   A   + +       QVT I + SKGF  + G G VH FEK ++K+ YKK REI IP D+ + DP   ++Q I D+ +SPSEET+V  T+  QLYS TLS+ ++ K GD + FELLS SFH+  I G+D+C RKP+IATC++DRSVRIWNYET  LE YKEF EE YSIALHPSGLYILVGFSDKLRLMN+LIDDIR FKEF+IRGC+EC+FS GGH FAAVH N+IQ+YS+T FE V +LKGHNGK+R V+W+ DD K+ISCGMDGAVYEW+    KR GESVLKSCSYT ++V+ DG+ T+AVG+D+T+KEI DSQ+LREV + D+ LT   +S SGRMLF GT +G++R+ KFPLT PGEWQE+  H+  I KM+++ +D YL T S+D  + I++  DKEGR +KRDK++G+AEEILITKSDLEEKNA MAEL+TRV+ELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKT+KDKEEAKHEE + + MEKHSKELQD+ESANNQKLM EYEKYQELQAKSQ+MQEDYERQL E+E  +EQ LEELTEYYE K  EK+  L+   ++ R Q  EYEETK+ IEEDADREILD K KYERRLREE+E+N RLKGETGIM+KK
Sbjct:    1 MSIAVATPRHCFGLKA----------------------------DKSQRFIPGSDKSVGMTAMAVSPNRRYVAIAEKG--EKATITIYDLHTLRKKKVLSHPEVQSAEFVSLAFSPDSKYLVSQSGRPDWTLLYWTWEKAKVMAFTK-SSNQQDSAVYQVSFNPQDNTQLCVVGNGIFKLFRYSEGNLKQFAFQKMEPQNFLCHAWVSDERIITGTDTGRLLLFESGELKNEFSVFGGGPSAPGTARQLSTAAIGADPSPTQTAYPQVTCIAAFSKGFICSGGAGTVHLFEKAEEKDAYKKSREIRIPTDTTNPDPQMIESQEIKDLTVSPSEETLVCSTSTSQLYSITLSTADLGK-GDLATFELLSQSFHHGVITGMDVCIRKPLIATCSLDRSVRIWNYETCSLEAYKEFQEECYSIALHPSGLYILVGFSDKLRLMNLLIDDIRYFKEFTIRGCRECSFSNGGHLFAAVHGNVIQLYSSTTFENVGNLKGHNGKVRQVIWSQDDSKIISCGMDGAVYEWNVYNYKREGESVLKSCSYTSVTVSPDGRTTFAVGSDRTIKEICDSQILREVPASDMVLTQCVMSRSGRMLFAGTASGTLRAMKFPLTVPGEWQEHQVHAGSINKMRMSYDDQYLFTASEDGSLYIYKAVDKEGRGLKRDKEVGYAEEILITKSDLEEKNAMMAELKTRVEELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTDKDKEEAKHEEEVADHMEKHSKELQDLESANNQKLMSEYEKYQELQAKSQKMQEDYERQLTEMEEAREQVLEELTEYYENKLQEKTAQLDQSQEESRQQLREYEETKKQIEEDADREILDIKNKYERRLREEKEANLRLKGETGIMRKK 854          

Query: 3088 DVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRK 3480
            DVEA V+RFKTDLYNCV +IQ+PK LKE++ ALY+K++Q++   +      A VDADIQ+E+ RQREHLERSVASLRKKL+KDSEIHRAD VRIMQENV+LIKEINDLR+ELK +RT  HDLE ALG+ RK
Sbjct:    1 DVEAVVKRFKTDLYNCVGFIQEPKKLKENVKALYQKYVQDETPES------AGVDADIQREYARQREHLERSVASLRKKLTKDSEIHRADNVRIMQENVTLIKEINDLRRELKIARTQVHDLETALGVMRK 125          

Query:   52 LKHVFGFRVG-VNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQI--CAIGNNFFKMFRYSENNLKNFGILK--VESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQ---VTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEI--TKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRG--CKECAFSYGGHYFA-AVHSNLIQIYSTTN-FEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKR-CGESVLKSCSYTGISVTQDGKNTYAVGT--DKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPG-EWQEYLGHSAQITKMKITPNDDYLVTI-SDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDEL--KMENEYQLRLKDMNYNEKIKELTEK 2163
            L+ V+G+R       + Y   + +VY      V+YN  + +Q+F  G +    + ++A+ P +  VA  +   +  P I ++D +S      L   +      T ++F+P   YL         +++ W W++ KQLASTR  +      +  + FNP     +  C + +  F   R +  N K  GI     E Q  LC  + SD+    GT +G++                        K +N  G + N     V +I   + GFA     G V  +    D E+    +  LI  ++     G S    I  +C     E I+  TN  +++    +  +   T +  H+  EL + + H           +K I AT + D+SVR+W+     L    +  ++  S+A +  G ++ VG SD    M +   D+      + R     E  +S  G + A   + N + IY+    ++ V   KG +  I ++ W+ D K L +         +   TGKR   +  +KS  +           T  VGT  +    + SD+    +V ++D             ++  G + G ++ FKFP  + G ++++Y+GHSA +T ++ + + + ++++   D  V  WR    EG +   D D+  A         L+  +       + +DEL   +ENE Q+      Y E +  L EK
Sbjct:   13 LEWVYGYRGHQCRNNLYYTASKEIVYFVAGVGVVYNTRENTQRFFLGHDDD--IISLALHPEKVLVATGQVGKD--PYICVWDSHSTETVSILK--DAHQRGITCLAFNPSGNYLVSVGLEDYHMVVVWDWKRGKQLASTRGHTD----RIFDMQFNPYKENVLVSCGVKHIIFWTLRGNSLNPKK-GIFGKTGEIQTNLCLAFGSDDVTYSGTLSGEIY---------------------KWKGQNLAGAIPNAHTGAVFSIFGGADGFASGSKDGTVVLW----DAEFKPIAKLDLI--NTRVGYEGLS----IRSVCWLG--EKILVGTNAGEVFEVMATDKDKPRTIVQGHAEGELWALAAH----------PKKGIFATGSDDKSVRLWSMADKSLLARTDVDQKVRSVAFNADGTHLAVGLSDG-SFMILKARDLSEVTRINDRKEVLHEMKYSPDGQFLAVGSNDNFVDIYAVAQKYKKVGECKGSSSFITHLDWSEDSKYLQTNSGAAERLFYRMPTGKRITNKEEIKSIHWA--------TWTCVVGTEVNGIWGKYSDTN---DVNALDACFQH-------NVMVTGDDFGLVKLFKFPSVRKGSKFRKYVGHSAHVTNVRFSNDFNRVISVGGGDHAVFQWRFL-PEGITDDHD-DLPEA-----VSGYLDSDSEESDSEASDIDELDSDVENEQQIDYSRTIYREDLPALKEK 657          

Query:   52 LKHVFGFRVGV-NGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSED-KPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLK------NFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLEN-NQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEY-YKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLS--STEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAY--SIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYG-GHYFAAVHSNLIQIYSTT---------NFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLK--EISDSQVLREVE---SVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFP---LTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWR 1953
            L+ V GF   V NG + + +   L+YP G+ +V+  I    Q  +SG   +  +T +A+S + RY+A  +      K  ++++D    + K  L+  ++   +  +++FSP+ +YL       D  ++ W  +  + +  +    P+A  + N ++F   +       GN   +++     N K      N G LK    N +  T   D     GT +G ++++         N+   L        E  +QG    V    ++   +   V  G G V      D K +   K    L  V+ +           I  + +          T + Q+Y F     + E      +     + + F +S I            ATC+ +  +R+WN  T++ EL +         ++ +   G   + G+ D           IR F+  S +   E + ++  G     V+S   +I S             +++  +K H G +  +    DD + +S   DG    W+  +  R  + V  +  +  +            GTD+ +   E  D  ++R++E   +  +Q   + L +S      G  +  ++ + +    +T  G      GHS  IT++KI PN  ++V++S D  ++ WR
Sbjct:   14 LESVIGFAGAVPNGLLVHPDRDHLIYPLGNTVVIEQIKTGKQSCLSG--HTDNVTCVAVSKSGRYLASGQQAHMGFKASVIVWDYAEKKLKYQLTLHKV---KVEALAFSPNDEYLVSLGGQDDGSVVVWDLQAGEAVCGSPAAVPSAG-TTNAVAFANHNDNLFITGGNKTLRVWELDRPNRKIRPTECNMGQLK-RIVNCIKVT-EDDTHFFCGTTSGDILMI---------NIQNRLFRHYGPAKEKFSQG----VTAMELIKGGQELLVGAGDGTV---AVVDCKNFKVSKANSKLCKVEGD-----------ITSIALRGQGHQFFVGTKLSQMYRFNFPEFTYERINTCHYDKVNDVVFPFGFSDIF-----------ATCSKNE-IRVWNTNTSK-ELLRIVVPNVTCNTVDIQKDGKAFVSGWDD---------GKIRVFRPESGQLFYEISDAHSKGVTAVIVNSTCSKIVSGGGEGQVRVWEGKKLLGMMKEHKGSVTCIKLKRDDTECVSASTDGTCIIWNLESFVR-SQIVFANTMFEAVCYHPSDCQIITAGTDRKIAYWETFDGALIRDLEGSSAGSIQGMDIALDDSVTHFVTGGADKLLKVWDYDAGQVTHLGG-----GHSGDITRVKICPNSRWIVSVSADGAILRWR 616          

Query: 1129 ILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYK--EFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTT---VTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKE 1968
            ILG+ +      I T   D S+R+W+YET + EL K  +  +  Y++AL P   +++ G                             AF +            ++I+      +V +LKGH   +  V+ T D K++IS   D  V  WD  T               GI++T DG+   +   D+TL+ I + +    V ++     T   V  S   +    G+ +  ++ +     K  E +  +GH++ I  + +TP+   +++  DD  V +W ++  E
Sbjct:   16 ILGIAVTPDTKKIITGGADGSIRVWDYETGK-ELNKLLDHTKLVYTLALSPHADFLVSG-----------------------------AFDH-----------TVKIWDMDTLSLVHTLKGHKNWVSGVLVTPDSKRIISSSYDKTVKIWDVETCAFVNSLDGHDGHVRGIAITSDGRRLVSASQDRTLR-IWNLETFAHVSTLRGHSETVYCVCCSPDDKFAISGSEDTMVKIWDLESAK--EVRSLVGHTSDIFAVAVTPDGSKVISSGDDTQVKVWSLESGE 256          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLN--SMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAAS------------LILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQE--DVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHD 3450
            M+  +A    + G R GV+  + + +E TLVY  GS+ V  N  QR Q+F  G EKS  + A+A+S + R++A++E    +   I ++DL     RKKK LSA +I A EF  I+FS DSKYL GQT  P+W+L++W WEK+K LAS + T+ +    VNQ+SF+P +STQ+C  G+  FK+ R SE  LK     +VE+ NFLCH WV ++R+I GTDTG+L++ E+G+IR E  + +             + L+EA+ +E+    L+   +T + S SKGF  + G G    FEK + ++ Y++ REI IP D        +  Q I  MC+SP+EET+   T   QL+S  +SS ++ K     +F+ +   FH S I GL +C RKP++ATC++DRSV IWNYET +L+LYK+F EEA+S+ALHP+G ++LVGFSDKLRLMN+L+DDIR F+EF++R C+ECAFS+GGH FAAV  N+I +YS  + E V++LKGH+GK+R++ W+ DD +L+SCGMDGAVYEW+T TGKR  ESVL+SCS+TG++ + D K+  AVG+D TLKE+ D QVLR V +     T + +S+SGR++F GT++G+IR+ K+PL    +W +   HS  ITKM IT +D +L+++++D  +++ ++ DK+GR +K ++ +  AEEIL+TK +LEEKN +M  L+ R++EL+ME+EY+LRLKD+NYNEKIKEL+EKF QE++SLKT  QV+  E +  + + E+   E+ +KH K+L+D+E + NQKL+LE+EK+Q+LQ K ++ +ED+++QL+  E  K QALEE T  YE K  EK+ +L    ++ + +     E  + +EED + ++   +IKYE++L+ E+E N  LKG+T  +K +   LQ ++ DQ  +  K Q E Q L ++I  LE D   L  +I    +TI++K+  I DLK K Q+L+K KF+ ++++ E +KQ E ++ EI+  +E I  ++ +L++  K ++QL L+  +L+ KLK+ +KE+    Q  +++E ++ R ++DL+ CV YIQ+P+ LKESI  LY  H+ E   V    +   E   + D+Q   T QR+ LE++V SL+ KL      H   Y R+ +E  ++I E N LRKEL   RT   D
Sbjct:    1 MSSISAQAHFILGLRTGVSNNLNFIDEHTLVYATGSSCVCLNTVQRFQRFFPGSEKSRSVRALAVSASHRFLAVSECG--ESACITVFDLQHEQGRKKKVLSAGDIHAQEFVCIAFSHDSKYLIGQTGAPEWMLVFWLWEKNKVLASVKTTTSSN--PVNQVSFSPHNSTQLCVSGSGVFKLLRLSEGVLKQTSTARVENFNFLCHAWVPEDRLIAGTDTGRLLVSESGDIRKEIRMMSKEGQSQADRQVKVMRLKEAEVVES----LSACPITAVFSYSKGFVCSTGPGTACLFEKME-QDSYRRSREIQIPPDPQGDQLTLADGQEIQSMCMSPAEETLAISTTRGQLFSVNVSSADMNK-EQKLHFDFVCQPFHSSPITGLSICFRKPLVATCSLDRSVHIWNYETKELDLYKQFQEEAHSVALHPTGFFVLVGFSDKLRLMNLLVDDIRVFQEFTVRSCRECAFSHGGHMFAAVSGNMIHVYSFISCENVLNLKGHSGKVRSIEWSVDDSRLVSCGMDGAVYEWNTQTGKRESESVLESCSFTGVAFSLDYKSALAVGSDLTLKEVQDGQVLRVVPADQDAHTAIAVSHSGRVVFTGTSSGAIRAIKYPLPSQRDWFQQRAHSGAITKMVITYDDQFLLSVAEDNCLLVSKIIDKDGRGLKSNRQVVHAEEILVTKLELEEKNQSMMALKMRLEELQMEHEYRLRLKDVNYNEKIKELSEKFQQEIKSLKTTQQVMTVEVETCKRESEKNSAELAKKHVKQLKDLERSFNQKLILEHEKFQDLQEKLKKTEEDHKKQLRSAEQSKVQALEEATHMYEAKLQEKTQLLAQSQQEAQLKISVLNEVIKQMEEDEELKLNAVQIKYEKKLQSEKEINLNLKGKTDDVKHEIRCLQAQVRDQSADTHKLQQERQSLRDLITALEGDIQELNMQIFGHKQTIENKDITISDLKGKIQQLEKLKFIYEFQLNEFRKQTETQKEEIKEQREMITTLKDDLQQMDKSSSQLKLSNSDLRLKLKAKDKEIFKNLQKVKNLELRLTRIRSDLHTCVGYIQEPRKLKESIKILYAHHVPEPGSVERDSEDVEEEEDEDDVQMTLTVQRDQLEKTVDSLKMKLDNSDAEHNKVYERMKKEKAAMITENNQLRKELLLIRTQVKD 1146          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLN--SMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAAS------------LILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQE--DVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHD 3450
            M+  +A    + G R GV+  + + +E TLVY  GS+ V  N  QR Q+F  G EKS  + A+A+S + R++A++E    +   I ++DL     RKKK LSA +I A EF  I+FS DSKYL GQT  P+W+L++W WEK+K LAS + T+ +    VNQ+SF+P +STQ+C  G+  FK+ R SE  LK     +VE+ NFLCH WV ++R+I GTDTG+L++ E+G+IR E  + +             + L+EA+ +E+    L+   +T + S SKGF  + G G    FEK + ++ Y++ REI IP D        +  Q I  MC+SP+EET+   T   QL+S  +SS ++ K     +F+ +   FH S I GL +C RKP++ATC++DRSV IWNYET +L+LYK+F EEA+S+ALHP+G ++LVGFSDKLRLMN+L+DDIR F+EF++R C+ECAFS+GGH FAAV  N+I +YS  + E V++LKGH+GK+R++ W+ DD +L+SCGMDGAVYEW+T TGKR  ESVL+SCS+TG++ + D K+  AVG+D TLKE+ D QVLR V +     T + +S+SGR++F GT++G+IR+ K+PL    +W +   HS  ITKM IT +D +L+++++D  +++ ++ DK+GR +K ++ +  AEEIL+TK +LEEKN +M  L+ R++EL+ME+EY+LRLKD+NYNEKIKEL+EKF QE++SLKT  QV+  E +  + + E+   E+ +KH K+L+D+E + NQKL+LE+EK+Q+LQ K ++ +ED+++QL+  E  K QALEE T  YE K  EK+ +L    ++ + +     E  + +EED + ++   +IKYE++L+ E+E N  LKG+T  +K +   LQ ++ DQ  +  K Q E Q L ++I  LE D   L  +I    +TI++K      LK   Q++DK    L     +L+ +++ ++ EI    +++                                          +++E ++ R ++DL+ CV YIQ+P+ LKESI  LY  H+ E   V    +   E   + D+Q   T QR+ LE++V SL+ KL      H   Y R+ +E  ++I E N LRKEL   RT   D
Sbjct:    1 MSSISAQAHFILGLRTGVSNNLNFIDEHTLVYATGSSCVCLNTVQRFQRFFPGSEKSRSVRALAVSASHRFLAVSECG--ESACITVFDLQHEQGRKKKVLSAGDIHAQEFVCIAFSHDSKYLIGQTGAPEWMLVFWLWEKNKVLASVKTTTSSN--PVNQVSFSPHNSTQLCVSGSGVFKLLRLSEGVLKQTSTARVENFNFLCHAWVPEDRLIAGTDTGRLLVSESGDIRKEIRMMSKEGQSQADRQVKVMRLKEAEVVES----LSACPITAVFSYSKGFVCSTGPGTACLFEKME-QDSYRRSREIQIPPDPQGDQLTLADGQEIQSMCMSPAEETLAISTTRGQLFSVNVSSADMNK-EQKLHFDFVCQPFHSSPITGLSICFRKPLVATCSLDRSVHIWNYETKELDLYKQFQEEAHSVALHPTGFFVLVGFSDKLRLMNLLVDDIRVFQEFTVRSCRECAFSHGGHMFAAVSGNMIHVYSFISCENVLNLKGHSGKVRSIEWSVDDSRLVSCGMDGAVYEWNTQTGKRESESVLESCSFTGVAFSLDYKSALAVGSDLTLKEVQDGQVLRVVPADQDAHTAIAVSHSGRVVFTGTSSGAIRAIKYPLPSQRDWFQQRAHSGAITKMVITYDDQFLLSVAEDNCLLVSKIIDKDGRGLKSNRQVVHAEEILVTKLELEEKNQSMMALKMRLEELQMEHEYRLRLKDVNYNEKIKELSEKFQQEIKSLKTTQQVMTVEVETCKRESEKNSAELAKKHVKQLKDLERSFNQKLILEHEKFQDLQEKLKKTEEDHKKQLRSAEQSKVQALEEATHMYEAKLQEKTQLLAQSQQEAQLKISVLNEVIKQMEEDEELKLNAVQIKYEKKLQSEKEINLNLKGKTDDVKHEIRCLQAQVRDQSADTHKLQQERQSLRDLITALEGDIQELNMQIFGHKQTIENK------LKDDLQQMDKSSSQLKLSNSDLRLKLKAKDKEIFKNLQKV------------------------------------------KNLELRLTRIRSDLHTCVGYIQEPRKLKESIKILYAHHVPEPGSVERDSEDVEEEEDEDDVQMTLTVQRDQLEKTVDSLKMKLDNSDAEHNKVYERMKKEKAAMITENNQLRKELLLIRTQVKD 1098          

Query:  118 LVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDK------PVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDS--KYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNL-KNFGIL-KVESQNF-LCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGK----VHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTN---IHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECA---FSYGGHYFA-AVHSNLIQIYSTT----NFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVD-VQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKP-GEWQEYLGHSAQITKMKITPNDDYLVTISD-DCVVMIWRV 1956
            +VY   S +V+YN +++ Q+   G   +  +  +++ P+   +A  +     K      P + I+D  S+     +          T +SFS  +   +L       D +L  W W+K KQLA  +     +N SV    F+P D+  I   G +    +      L K  G+  K E   + LC  +  +   I G  +G + +   G  R    ++ +           ++G + ++ V       K   +  G GK    V W     D +Y KK  E+ +   S+S  P ++ A+          EE  V  T    I   +  TL  T I +              H  ++ GLD+        TCA D+ V++W+  ++Q    K   ++A S+  HPSG  + VG      L  +L  D R        G +  +   +S  G++ A   H N + IY+ +     +  V    GH+  + ++ W+ + + +++   D  +  W+ + GK            T +   ++ +   +  T      +S + +    ES D   +     S+ G +L    + G +  F FP ++P     EY GHS+ +T +    +D  L++    D  ++ W V
Sbjct:  223 IVYFIASVVVLYNTEEQQQRHYLG--HTDDVKCLSVHPDMVTIATGQVAGNSKEGKLLAPHVRIWDSVSLNTVHVIGMGG-FDRAVTCVSFSKSNGGAFLCAVDDANDHILSVWDWQKEKQLADVK----CSNDSVLAAVFHPMDNNLIVTCGKSHINFWTMEGRTLTKRQGLFEKHEKPKYVLCVAFAENGDTITGDSSGNIYIWAKGGSRISHAVSGA-----------HEGGIFSICVL------KDGTMVSGGGKDRRVVLW-----DHDYRKKA-EMEV---SDSLGPVRALAE-------GKPEELFVGTTKNAIIRSAFPDTL--TPIVQG-------------HTDELWGLDVHPSMEQFVTCAQDKLVQLWDSNSHQPLWSKSIEDQARSVGFHPSGAVLAVGTMTGRWL--VLDADTRDLVSVHTDGNEMISTIRYSPDGNFLAVGSHDNFVYIYAVSEGGRKYSRVGKCSGHSSFVTHLDWSANSQYIVTNSGDYEILFWEASNGKHV----------TNVDTVRNLEWATSTCT------LSFNTLGIWPESADGTDINAACRSHGGSLLASADDFGKVHLFTFPCSQPRAPSLEYGGHSSHVTNVAFLHDDSRLISSGGKDTSILQWAV 791          

Query:  118 LVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDK------PVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDS--KYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNL-KNFGIL-KVESQNF-LCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGK----VHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTN---IHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECA---FSYGGHYFA-AVHSNLIQIYSTT----NFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVD-VQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKP-GEWQEYLGHSAQITKMKITPNDDYLVTISD-DCVVMIWRV 1956
            +VY   S +V+YN +++ Q+   G   +  +  +++ P+   +A  +     K      P + I+D  S+     +          T +SFS  +   +L       D +L  W W+K KQLA  +     +N SV    F+P D+  I   G +    +      L K  G+  K E   + LC  +  +   I G  +G + +   G  R    ++ +           ++G + ++ V       K   +  G GK    V W     D +Y KK  E+ +   S+S  P ++ A+          EE  V  T    I   +  TL  T I +              H  ++ GLD+        TCA D+ V++W+  ++Q    K   ++A S+  HPSG  + VG      L  +L  D R        G +  +   +S  G++ A   H N + IY+ +     +  V    GH+  + ++ W+ + + +++   D  +  W+ + GK            T +   ++ +   +  T      +S + +    ES D   +     S+ G +L    + G +  F FP ++P     EY GHS+ +T +    +D  L++    D  ++ W V
Sbjct:  245 IVYFIASVVVLYNTEEQQQRHYLG--HTDDVKCLSVHPDMVTIATGQVAGNSKEGKLLAPHVRIWDSVSLNTVHVIGMGG-FDRAVTCVSFSKSNGGAFLCAVDDANDHILSVWDWQKEKQLADVK----CSNDSVLAAVFHPMDNNLIVTCGKSHINFWTMEGRTLTKRQGLFEKHEKPKYVLCVAFAENGDTITGDSSGNIYIWAKGGSRISHAVSGA-----------HEGGIFSICVL------KDGTMVSGGGKDRRVVLW-----DHDYRKKA-EMEV---SDSLGPVRALAE-------GKPEELFVGTTKNAIIRSAFPDTL--TPIVQG-------------HTDELWGLDVHPSMEQFVTCAQDKLVQLWDSNSHQPLWSKSIEDQARSVGFHPSGAVLAVGTMTGRWL--VLDADTRDLVSVHTDGNEMISTIRYSPDGNFLAVGSHDNFVYIYAVSEGGRKYSRVGKCSGHSSFVTHLDWSANSQYIVTNSGDYEILFWEASNGKHV----------TNVDTVRNLEWATSTCT------LSFNTLGIWPESADGTDINAACRSHGGSLLASADDFGKVHLFTFPCSQPRAPSLEYGGHSSHVTNVAFLHDDSRLISSGGKDTSILQWAV 813          

Query:   49 HLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVE-------SQNFLCHTWVSDERVILGTDTGKLILVENGEIRTE 726
            HL H FGF       +   ++ TL++  G+ +V+ ++  + Q+F+        + A+A+ P+R + A+AE  +   P I++Y+  S+R  + L       + ++ +SF+ D   LA     PD+LL  W W + +++ S + TS      V+++SF+  D   +   G      ++ S      F + K+        + +      + D  V+ GT+ G L+L +   I+ E
Sbjct:   48 HLSHSFGFDSRRRANLGVLDDSTLIFIAGNLMVLLDVHAQEQRFLR-SSGGGGIGAIAVHPSREFFAVAEKGTS--PDIIVYEYPSLRPGRILRGGT--RHRYSCVSFNHDGSLLASVGGEPDFLLTLWDWRR-EEVQSFQATSQ----EVHRVSFSHYDQELLTTAGCRHINFWKLS-TTFTGFKLEKLAGHFGNSVASDIEGVLELPDGEVVSGTEWGNLLLWDGNSIKAE 269          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGMESGRLIXXXXXXXXXXXXAPDEIATRSILSAGERLPPIDT 3747
            MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACT+IHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLQKEIDDQKEEIKKFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDELKQKLKSTEKELKTERQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGMESGRLINTNTNNNGGNTGAPDEIATRSILSAGERLPPIDT
Sbjct:    1 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTDIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLQKEIDDQKEEIKKFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDELKQKLKSTEKELKTERQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGMESGRLINTNTNNNGGNTGAPDEIATRSILSAGERLPPIDT 1239          

Query:   31 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLXXXXXXXXXXXXXFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDVSGTQKQTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGMESGRLIXXXXXXXXXXXXAPDEIATRSILSAGERLPPIDT 3747
            MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACT+IHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLQKEIDDQKEEIKKFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDELKQKLKSTEKELKTERQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDV      TSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGMESGRLINTNTNNNGGNTGAPDEIATRSILSAGERLPPIDT
Sbjct:    1 MAIAAAHLKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTDIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCKECAFSYGGHYFAAVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPLTKPGEWQEYLGHSAQITKMKITPNDDYLVTISDDCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKIKELTEKFIQEMESLKTKNQVLKTEKDKEEAKHEERLHEMMEKHSKELQDIESANNQKLMLEYEKYQELQAKSQRMQEDYERQLQELESQKEQALEELTEYYETKQAEKSTILENLNKDMRDQTMEYEETKRLIEEDADREILDTKIKYERRLREERESNARLKGETGIMKKKFASLQKEIDDQKEEIKKFQTETQKLENVIRNLEKDKIGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEPRELEIQSAKEQIQEMESELERFHKQNNQLTLNIDELKQKLKSTEKELKTERQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKESIVALYKKHIQEDV------TSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELEEAGRVMEMQRALIGQLRDKIVGMESGRLINTNTNNNGGNTGAPDEIATRSILSAGERLPPIDT 1233          

Query:   52 LKHVFGFR-VGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNL----KNFG-ILKVESQNFLCHTWVSDERVIL--GTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEY--YKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQ--LELYKEFAEEAYSIALHPSGLYILVGFSDKLRLMNILIDDIRTFKEFSIRGCK-----ECAFSYG-GHYFA-AVHSNLIQIYSTTNFEVVMSLKGHNGKIRNVVWTTDDKKLI--SCGMDGAVYEWDTNTGKRCGESVLKSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFPL-TKPGEWQEYLGHSAQITKMKITPNDDYLVTISD-DCVVMIWRVQDKEGRSVKRDKDIGWAEEILITKSDLEEKNATMAELRTRVDELKMENEYQLRLKDMNYNEKI-KELTEKFIQEMESLKTKNQVLKTEKDKE 2229
            L+ V G+R       I Y     +V+   +  ++ NI  ++Q+F +    +  +  + + P +  +A  E   E  P I ++D  +M+    L           ++ FS D K LA      + LL+ W W K ++LASTR    A    +  I ++P ++ Q+ A+G  F + +             FG + K+++Q  LC  +  ++  +   G+ +G L+ +    I     L +++++ E                  I +  KGF      G +   ++T  K +  YK   E L P             Q+++  C  P+  ++V      ++ + T SS EI ++       +L       ++ GL +   K I AT + D  + IW  E +   L   K+    A    +   G  + VGF D     + L+  + +  E +    +     +  FS   G Y A   H N + IYS  + + +   KG +  I ++ W+TD K L+  S   +   +E    T +   ++ ++   +   S    G +   +   K   +I+D             + +V+L++ G++L  G + G ++ F++P  TK  ++++YLGHSA +T ++   ND+YL+++   D  +M+W    K  R     +D    ++I + +SDL +   T +E     D   +E E  +      Y+E++ ++ TE    ++ S  T N  LK    +E
Sbjct:  675 LEWVHGYRGYDCRNNIFYLQSGEIVFHVAAVGIVMNIASKTQRFYA--SHNDDILCLGLHPLKDLIATGEVGRE--PTIHVWDTQTMKSVSILKGEH--ERGVCAVDFSSDGKKLASVGLDDNHLLVVWDWRKGEKLASTR----AHKDKIFMIKWDPHNNNQLVAVGMKFIRFWTQVGGGFTTKRGTFGNVAKLDTQ--LCAAYNPNKPGVCYTGSPSG-LVYIWKDNI-----LQSAVMMHEGG-------------CYAIDALDKGFVTGGKDGTIKLCDETFTKVHKSYKLSPENLQP------------QQMLSSAC--PTIRSVVLGKG--KILAST-SSGEIMELSTDGTINILVQGHGEGELWGLAVHPSKNICATVSDDCYLMIWEVEPSNHKLIKLKKLKGPARCCDISCDGSAVAVGFKDG----SFLVLSLTSLGEIASSHHRKEEISDIKFSPAPGKYLAVGSHDNFVDIYSAISHQRLSVCKGCSSYITHLDWSTDGKLLMVNSGAKEQLFFEAPRGTRQIIAKTEIEKIIWASWSCVL-GDSCIGIWPPKC--DITD-------------INSVSLTSDGKVLATGDDFGRVKLFEYPSKTKFAKFKQYLGHSAHVTNVRWLHNDEYLLSVGGADTALMVW----KHRRDPVPLEDSINNKKINMPQSDLSD---TDSEEENGFDS-DVEREKSMDYIAKTYSERLNQQQTESLKPDLVSQTTSNNNLKASVSRE 1348          

Query:   52 LKHVFGFRVG-VNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSENNLKN----FG-------ILKVE---SQNFLCHT---------WVSD--ERVILGTDTGKLILVEN---GEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGLGKVHWFEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCISPSEETIVACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSIALHPSGLYILVGFSDK----LRLMNIL-IDDIRTFKEFSIRGCKECAFSYGGHYFA-AVHSNLIQIY-STTNFEVVMSLKGHNGKIRNVVWTTDDKKLISCGMDGAVYEWDTNTGKRCGESVL----KSCSYTGISVTQDGKNTYAVGTDKTLKEISDSQVLREVESVDVQLTTVTLSNSGRMLFCGTNNGSIRSFKFP-LTKPGEWQEYLGHSAQITKMKITPNDDYLVTI-SDDCVVMIWRVQD 1962
            L  V+G+R    +  + Y N + +VY      ++Y+I QR Q +    E +  + ++A++ +   VA  +      P I I++ NS+  K  L       +  +S++FS +  YL      P+  L  W W+K K L+STR  S     +   +S  P    +    G    K +    N L +    +G       IL V    S N +C++         W  +  ERVI    +G L  +E+   G +    +    L   E Q +      L N+    ++  S           VHW                     SN+   G   + II     +P++                      + M  H+  EL +   H           +K I AT + D S+RIW     +        ++  S   +  G  I +G  D     +R  +++ + + +  KE       E  FS  GH+ A   + N + IY +T +F+     KG++  I ++ W+ D   + +      +  +    G+   ++ L    K   +TG+ +  D +  +A  TD             ++ + DV L       +  ++  G + G ++ F +P  TK   +++Y GHSA +T ++ + +  +L++I   D  +  WR+ D
Sbjct:   13 LDWVYGYRGHQCHNNLFYTNSEKIVYFVAGIGIVYDIKQRKQFYY--FEHNDDIISLALASDGELVATGQVGKS--PFICIWNSNSLETKSILKDQH--THGISSVAFSKNGMYLLSVGLDPNATLNVWDWKKGKVLSSTRAHSDRVFDARFMVSDGP---IKFVTCGIKHIKFWSLCGNTLSSKKGIYGKKGEIQTILTVCMSISDNAVCYSGTLNGDVYIWRENNLERVIATVHSGALYSIESCASGYVTGGKDSCVVLHDPEFQPMTRIDLKLTNIGYPNLIVRS-----------VHWL--------------------SNNVLVGTQGSDIIEIPVSTPNKPK--------------------SLMMGHAAGELWALGVH----------PKKSIFATGSDDCSLRIWQMNEREPLTTLRIDKKIRSCGFNHDGSLIAIGIMDGSFSVIRTRDMIEVHNAQDRKEV----LHELKFSPDGHWLAVGSNDNFVDIYDATASFKRTGVCKGNSSFITHLDWSLDSTYIRTNSGAAELLIFKAPGGEHITQTQLLTSIKWAMFTGV-LGTDIQGIWAKYTDT-----------NDINAADVNL-------NANLIATGDDFGLVKLFNYPSPTKGAHFRKYTGHSAHVTNVRWSFDKKFLISIGGGDQSIFQWRLTD 598          

Query:   52 LKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYSE--------NNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGL-GKVH-W-FEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCI-----SPSEETIV--ACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSI-----ALHPSGLYILVGFSDK-LRLMNI 1329
            L H FG+       +A  ++QTL Y  G+ +   N+   S  ++  L     +  MA+ P + Y+A+ E  S+  PV  IY+  S++  + L   +     ++   F+   + LA   S PD++L  W W+  +    T L S A +  + +++++      +   G    + ++ ++         ++  FG  K E  +      + D +V+ G++ G + LV +GE+         + +    K   + G +N + +       +G  +  G  GK++ W FE  D  E  +++            DP  ++  + ND  +     SP  E+ +  A     +++   LS +  +   +  N      +FH  +I   D+     + A+   D S+R++++   +L    +F  E   I      + P G  ++ GF D  +R++N 
Sbjct:   96 LAHSFGYNCQKRDNLALLDQQTLCYISGNYIEFMNLSDFSHSYLRSL-SGEGIGCMAVHPTKMYLAVGEKKSDSPPVTAIYEYPSLKLYRILR--DGTEKAYSYCQFNTSGELLATVGSDPDFMLTVWEWKNEQ----TVLRSKAFSQDIYRVAWSADLEGVLTTAGTGHIRFWKMADTFTGLKLQGDIGKFG--KTEISDIEGFVVLPDGKVLSGSEWGNM-LVWDGEL-------IKVQIGRKNKKPCHSGTINQIII------EEGELMTLGTDGKINTWDFETIDTAEVAEEMATF-------EMDP-MNELLVSNDAKLMHVVKSPETESSIWYAQDGNGKIWKLDLSFSHTSAPPEILN------TFHSGEIRDCDVSPLSYLSASIGSDGSLRVFDFAARKLMAEMKFNFEGSKILWAPLKVDPKGKTVIAGFHDGVIRILNF 508          

Query:   52 LKHVFGFRVGVNGAIAYQNEQTLVYPCGSNLVMYNIDQRSQKFISGLEKSHKMTAMAISPNRRYVALAETTSEDKPVIVIYDLNSMRKKKTLSAPEILANEFTSISFSPDSKYLAGQTSGPDWLLIYWAWEKSKQLASTRLTSPAANFSVNQISFNPQDSTQICAIGNNFFKMFRYS--------ENNLKNFGILKVESQNFLCHTWVSDERVILGTDTGKLILVENGEIRTEFNLAASLILEEAQKLENNQGVLNNVQVTTIVSSSKGFAVACGL-GKVH-W-FEKTDDKEYYKKVREILIPVDSNSADPGKSQAQIINDMCI-----SPSEETIV--ACTNIHQLYSFTLSSTEITKMGDHSNFELLSYSFHYSQILGLDLCRRKPIIATCAVDRSVRIWNYETNQLELYKEFAEEAYSI-----ALHPSGLYILVGFSDK-LRLMNI 1329
            L H FG+       +A  ++QTL Y  G+ +   N+   S  ++  L     +  MA+ P + Y+A+ E  S+  PV  IY+  S++  + L   +     ++   F+   + LA   S PD++L  W W+  +    T L S A +  + +++++      +   G    + ++ +        + ++  FG  K E  +      + D +V+ G++ G + LV +GE+         + +    K   + G +N + +       +G  +  G  GK++ W FE  D  E  +++            DP  ++  + ND  +     SP  E+ +  A     +++   LS +  +     +  E+L+ +FH  +I   D+     + A+   D S+R++++   +L    +F  E   I      + P G  ++ GF D  +R++N 
Sbjct:   96 LAHSFGYNCQKRDNLALLDQQTLCYISGNYIEFMNLSDFSHSYLRSL-SGEGIGCMAVHPTKMYLAVGEKKSDSPPVTAIYEYPSLKLYRILR--DGTEKAYSYCQFNTSGELLATVGSDPDFMLTVWEWKNEQ----TVLRSKAFSQDIYRVAWSADLEGVLTTAGTGHIRFWKMADTFTGLKLQGDIGKFG--KTEISDIEGFVVLPDGKVLSGSEWGNM-LVWDGEL-------IKVQIGRKNKKPCHSGTINQIII------EEGELMTLGTDGKINTWDFETIDTAEVAEEMATF-------EMDP-MNELLVSNDAKLMHVVKSPETESSIWYAQDGNGKIWKLDLSFSHTS-----APPEILN-TFHSGEIRDCDVSPLSYLSASIGSDGSLRVFDFAARKLMAEMKFNFEGSKILWAPLKVDPKGKTVIAGFHDGVIRILNF 508