Transposon Ty3-I Gag-Pol polyprotein

Query: 2248 PWNTPLVCVWKKEKKDIRLCLDFRQL-NKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQE---KTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQ-KDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAI 3192
            P   P   V  + ++  RL  ++  L + +T RQ + +  + E+ D LHG+ +F+ ++L     +  ++    E   K AF   E +   +  PF ++  P   Q ++  +LKD+    V+ Y  ++LI++ ++E+H +   +VL +     +  + +K Q  R+ V+FLG ++   G++ +   +  I  +  P    +LR+F+     YR F++ ++  A  L      ++ +  W    ++AF  +K A   AP+L  P  +  F L+T  +   + A L Q  D+ G     A+ S  +S  E  Y     ++L I
Sbjct:  611 PSTAPWEPVGARMQERARLQEEYWDLQDMLTNRQDY-IQMIPELFDQLHGAEWFTKLELRGTIVEESVNGHRTEDVWKAAFGL-ELEEMKSYQPFALSPDPIIPQNVIHFILKDMLGFFVLSYGQEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQFHRQTVEFLGFVVTPKGVKLNKNVMTIITGYPTPGSKLSLRNFIEFVFPYRHFVERFSIIAEPLVRQL-LSSYQFYWGVEEQEAFECLKRAFRKAPLLHHPKPQNPFYLETGVTGTALHASLIQIDDQTGKRACCAFYSRNISPIEVEYSQAEMKILPI 927          

Query: 2248 PWNTPLVCVWKKEKKDIRLCLDFRQL-NKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQE---KTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQ-KDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAI 3192
            P   P   V  + ++  RL  ++  L + +T RQ + +  + E+ D LHG+ +F+ ++L     +  ++    E   K AF   E +   +  PF ++  P   Q ++  +LKD+    V+ Y  ++LI++ ++E+H +   +VL +     +  + +K Q  R+ V+FLG ++   G++ +   +  I  +  P    +LR+F+     YR F++ ++  A  L      ++ +  W    ++AF  +K A   AP+L  P  +  F L+T  +   + A L Q  D+ G     A+ S  +S  E  Y     ++L I
Sbjct:  611 PSTAPWEPVGARMQERARLQEEYWDLQDMLTNRQDY-IQMIPELFDQLHGAEWFTKLELRGTIVEESVNGHRTEDVWKAAFGL-ELEEMKSYQPFALSPDPIIPQNVIHFILKDMLGFFVLSYGQEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQFHRQTVEFLGFVVTPKGVKLNKNVMTIITGYPTPGSKLSLRNFIEFVFPYRHFVERFSIIAEPLVRQL-LSSYQFYWGVEEQEAFECLKRAFRKAPLLHHPKPQNPFYLETGVTGTALHASLIQIDDQTGKRACCAFYSRNISPIEVEYSQAEMKILPI 927          

Query:  803 CWTCQKPGHSSRECNIKRRFQCYACGVEGHIRRECPTIKCHRCNARGH 946
            C+ C KPGH +R+C+     +CY+CG  GHI+++C  +KC+RC   GH
Sbjct:  100 CYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGH 147          

Query:  803 CWTCQKPGHSSRECNIKRRFQCYACGVEGHIRRECPTIKCHRCNARGH 946
            C+ C KPGH +R+C+     +CY+CG  GHI+++C  +KC+RC   GH
Sbjct:   99 CYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGH 146          

Query:  803 CWTCQKPGHSSRECNIKRRFQCYACGVEGHIRRECPTIKCHRCNARGH 946
            C+ C KPGH +R+C+     +CY+CG  GHI+++C  +KC+RC   GH
Sbjct:   93 CYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGH 140          

Query: 2185 DKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEK-GHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGK--RFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGK--IKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNTVLTKQGKIWIPSDNRQRMIKEVHV--LLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXX-XXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINK-QDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFG 4302
            + +E+ I +     IIR  +SP       V KK+   +R C+D+R LN IT +  +P+P +    + L G+ +F+ +DL NAY+ V++ +  + KTAF+T  G F +  +PFG++ AP  FQ L+  VL+D+    + VYLDDILIF+ + ++H     +VL ++   GL +  EKC    + V FLGHI++ +G++ D  K++A+  +  P   K L+ FLG  N+YRRFI+++++ A  L ++        RW+   + AF  +K   ++AP+L+ PD  ++F+++ DAS   +GA+LSQ+    G  H  AY SH +++ E+ Y I  +ELLA+    + + H+L G    F++ TDHK + ++ + K+ + ++   W  +    D  + YR G+ +   D LSR         + +H +  +    I  R L ++A      W+ ++     ++       C              ++++P + R  +I+  H   L CH G  +    I+       +A +++  +  C  C   KT               + P+  I +D    L  + N    I  ++D +SK      + K    R  +  +++      G P ++  D G  F ++  +E     G  +  SS +H  +NG  ER  + +   +   +++    +W+  +  +EY  N+     TG+SP E   G
Sbjct:  538 EAMEKYISDSLAAKIIRPSSSPAGAGFFFV-KKKDGSLRPCIDYRGLNAITVKNTYPLPLMSSAFERLQGASFFTKLDLRNAYHLVRIREGDEWKTAFNTPRGHFEYCVLPFGLSNAPAVFQALVNDVLRDMLDQFIYVYLDDILIFSHSLQEHVQHVRRVLQRLLENGLYVKAEKCVFHAQSVPFLGHIVSVEGMRMDPEKVQAVVDWPTPDSRKALQRFLGFANFYRRFIRNFSQLAAPLTALTSLKT-PFRWSNAAQVAFDRLKSCFVSAPILIAPDPSRQFVVEVDASEVGVGAILSQRSSSDGKMHPCAYFSHRLNNAEQNYDIGNRELLAVKLALEEWRHWLEGSGVPFIVWTDHKNLEYIQSAKR-LNSRQARWALFFGRFDFSISYRPGSKNVKPDALSR---------IFDHSERASSPETIVPRRLFISAV----TWEIESRVRMALEGVTPPPGC-----------PPSRLFVPEELRSDVIRWGHSSKLACHPGVSRTLYLIKQRFWWPVMARDIRNFVLACSVCAVSKTSNRPPAGLLQPLSVPSRPWSHIALDFVTGLPPS-NGNTVILTVVDRFSKATHFIPLPKLPSARETAAAVIDHVFRIHGLPTDVVSDRGPQFISKFWREFCHLMGATVSLSSGFHPQSNGQTERANQDLERMLRCLVSQNP-SSWSQQLSWVEYAHNSLPVSATGLSPFECSLG 1223          

Query: 1651 CLLDTGARINVMAKSVIDRLE-NIEILETRESLRCANNSRLETMGKLNINVKM---GSMERNVTFIIVKNLIPEIIGGVELQRL------FGIELKYILEEHEKRSDFICEIEARFGRIITDEERLRHAIDVLKVTGNKR-LLEIFQANKNVFMADKWDIGCT-NLIKHKIITKGEPIMIK-PRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEK-GHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGK--RFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNT--VLTKQGKIWIPSDNRQRMIKEVHV--LLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXX-XXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSK---YISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFG 4302
             L+D+GA  N +   +++ L+     L +  +++  +   L T+  +   +++   G+   N++F + K++   +I G     L      +G    +   E   +S  +         +  +E+     +D+  V      L  +F  ++   +       C  +L+      KG+   +  P R      + +E+ I +     IIR  +SP       V KK+   +R C+D+R LN IT +  +P+P +    + L G+ +F+ +DL NAY+ V++    + KTAF+T  G F +  +PFG++ AP  FQ L+  VL+D+    + VYLDDILIF+ + ++H     +VL ++   GL +  EKC    + V+FLGHI++ +G++ D  KI+A+  +  P   K L+ FLG  N+YRRFI+++++ A  L S+   +    RW+   E AF ++K   ++AP+L+ PD  ++F+++ DAS   +GA+LSQ+    G  H  AY SH +S  E+ Y I  +ELLA+    + + H+L G    F++ TDHK + ++ + K+ + ++   W  +    +  + YR G+ +   D LSR         + +  D  +         V  +G         + V  I  ++E++  +  +   T  +     ++++P + R  +++  H   + CH G  +    I+       +A +V+  +  C  C   K+               + P+  I +D    L  + N    +  ++D +SK   +ISL  +    E  ++  +++      G P ++  D G  F +R  +E  +  G  +  SS +H  +NG  ER  + +   +   +++    +W+  +  +EY  N+    +TG+SP +   G
Sbjct:  332 ALIDSGAEGNFIDSDLVNELKIPFSPLSSPIAVQALSGLSLPTITHITAPIRLVTSGNHTENISFFLTKSVNNPVILGHPWLVLHKPHINWGHSAVFSWSESCHKSCLLSACSTVPCSVFQEEQ-----VDLSNVPREYHDLKRVFSKSRAASLPPHRPYDCAIDLLPGTSPPKGKLYSLSVPER------EAMEKYISDSLAAKIIRPSSSPAGAGFFFV-KKKDGSLRPCIDYRGLNSITVKNTYPLPLMSSAFERLQGANFFTKLDLRNAYHLVRIRPGDEWKTAFNTPRGHFEYCVLPFGLSNAPAVFQALVNDVLRDMIDQFIYVYLDDILIFSHSLQEHVQHVRRVLQRLLENGLYVKAEKCVFHAQSVQFLGHIVSVEGMRMDPEKIQAVVDWPTPDSRKALQRFLGFANFYRRFIRNFSQLAAPLTSLT-SSKMPFRWSSAAEAAFSKLKGCFVSAPILIAPDPSRQFVVEVDASEVGVGAILSQRSSSDGKIHPCAYFSHRLSPAERNYDIGNRELLAVKLALEEWRHWLEGSGVPFIVWTDHKNLEYIRSAKR-LNSRQARWALFFGRFNFTISYRPGSKNIKPDALSR---------LFDPSDRLSSPDP-----VLPQG---------IVVANISWEIESR-VRTALNGVTPPIGCPPSRLFVPEELRSDVVRWGHSSKVACHPGVSRTLFVIKQRFWWPTMARDVRDFVLACSVCAVSKSSNRPPAGLLQPLSVPSRPWSHISLDFVTGLPSS-NGNTVVLTVVDRFSKAAHFISLPKLPSARETAVA--VIDHVFRIHGLPTDVVSDRGPQFVSRFWREFCRLLGATVSLSSGFHPQSNGQTERANQDLERTLRCLVSQNP-SSWSQQLSWVEYAHNSLPVSSTGLSPFQCSLG 1197          

Query: 1645 VDCLLDTGARINVMAKSVIDRLENIEILETRESLRCANNSRLE--TMGK------LNINVKMGSM-ERNVTFIIVKNLIPEIIGGVELQRLFGIELKYILEEHEKRSDFICEIEARFGRIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADK---------WDIGCTNLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKD--IRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQK-DEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGK--RFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNTVLTKQGKIWIPSDNRQRMIKEVHVLLC--HAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXX-XXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILK-FGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKIDRMKWYSNKEI--NREDMEKRIED--KTLKPKISKTVR--------------NFEM-EDVVLIKQEIR-----NKDDARWEGPYKVIKKIHERSYLLK 4533
            V  L+D+G+ +N++++ + D+L+    + T   +   N +R++  T+G         +++ +G   E  +TF ++ +   E+I G        I    I     + + +    + R    I     L  +I+  +V     L + ++    VF   K         WD  C   +   +      I    R +   +E  IEEA+    ++G IR   SP       +   EKKD  +R C+D+R LN IT +  +P+P V   L+ L  +R ++ +DL +AY  +++ +  + KTAF T  G + +  MP+G+A +P  FQ  + +V +DL    V+ Y+DDILI++   E H      VL ++    L    EKC+    +  FLG+II+  G++ +NTK++A+  +  PK VK L+ FLG  N+YRRFI++Y+  +  L S+      K++W     K+F ++K +  TAP+L  P+    F+++ DAS   IGAVLSQ+    G  H  AY S  +++ E+ Y +  KELL++    + + H+L G    F + TDHK + ++ + ++ +  +   W  + +  +  + YR GT +  AD LSR+           ++  +  +    IL  +       W  D ME  EI+   ++         N       + ++P   R R+++ VH  L   H G  +    ++N      +  ++   +++C  C + KT                 P+  + +D    L  + N    I  IID +SK   L  +        +   L + + + +G P+++  D G  F ++  K   K   I +  +S YH  +NG +ER  + I  Y+    +    K W++ +P  EY  N+    +TG++P + I G +     W     +  + +D  +R E+   +   ++ + +R              N++  + V L  +++R      K   R+ GP+K++K+I+  +Y L+
Sbjct:  332 VSALVDSGSAVNIISQELTDKLK----IPTSPCVPVINITRIDNGTIGSGIKAITQPVSLSIGLFHEETITFYVIPSCKYEVILG---HPWLTIHDPTISWNQGELTHWSTHCQQRCFSKILSLPCLSTSIESPEVHSQVTLPQPYREFAEVFNKSKAAQLPPHRSWD--CAIELLPNMSPPKSKIYPLSRPETQAMETYIEEAL----SSGYIRPSTSPAAAGFFFI---EKKDGGLRPCIDYRGLNNITVKYRYPLPLVPPALEQLREARIYTKLDLRSAYNLIRIREGDEWKTAFLTTRGHYEYLVMPYGLANSPAVFQSFINEVFRDLLNKCVIAYIDDILIYSPNLEQHIKDVRTVLTRLQENQLYAKLEKCEFHMSKTSFLGYIISHHGVEMNNTKVQAVTGWPLPKTVKELQRFLGFANFYRRFIRNYSLISAPLTSLLKGKPSKLKWNPETVKSFEKLKTSFTTAPILKHPNPELPFVVEVDASDYGIGAVLSQRHGNPGKLHPCAYFSRKLTAAERNYDVGNKELLSMKAALEEWRHWLEGAVHPFQIITDHKNLEYIKSARR-LNPRQARWSLFFTRFNFTVTYRPGTKNHKADALSRR-----------YDQGQLDQTPVSILPPSVVIAQISW--DIME--EIQRGQQDDPPPPECPPN-------RQYVPQTLRLRIMQWVHNSLSSGHPGISRTLNLVRNAFWWPKMNQDITTFVKSCAVCAQSKTPRELPSGLLQPLPIPHRPWSHLSIDFVTDLPNS-NNYTTILVIIDRFSKACRLIPLKGLPTAMETALELFQHVFRVYGIPEDIVSDRGPQFTSKVWKAFCKQLDINVSLTSGYHPESNGQVERLNQEIGRYLRTYCSREQDK-WSNFLPWAEYAQNSLTHSSTGLTPFQCILGYQPPMFPWSGEPSMVPSVDDWVQRSEEVWNSAHVRLQRAIRTQRINADQRRRPNPNYQPGQRVWLSTRDLRLRLPSRKLSPRYVGPFKILKRINNVTYRLE 1304          

Query: 2227 IIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEK-GHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGK--RFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNT--VLTKQGKIWIPSDNRQRMIKEVHV--LLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXX-XXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINK-QDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFG 4302
            IIR  +SP       V KK+   +R C+D+R LN IT +  +P+P +    + L G+ +F+ +DL NAY+ V++    + K+AF+T  G F +  +PFG++ AP  FQ  +  VL+D+    + VYLDDILIF+ + ++H     +VL ++   GL +  EKC    + V FLGHI++ +G++ D  KI+A+ ++  P   K L+ FLG  N+YRRFI+++++ A  L ++   +    RW+   E AF ++K   ++AP+L+ PD  ++F+++ DAS   +GA+LSQ+    G  H  AY SH +S+ E  Y I  +ELLA+    + + H+L G    F++ TDHK + ++ + K+ + ++   W  +    +  + YR G+ +   D LSR    +      E   +    +  RI+                 +  I  ++E+K  +  ++  T  +     ++++P   R  +I+  H   + CH G  + +  I+       LA +V+  +  C  C   KT               + P+  I +D    L  + N    I  ++D +SK      + K    R  +  ++N      G P ++  D G  F ++  +E  +  G  +  SS +H  +NG  ER  + +   +   +++    +W+  +  +EY  N+     TG+SP +   G
Sbjct:  554 IIRPSSSPAGAGFFFV-KKKDGSLRPCIDYRGLNNITVKNTYPLPLMSSAFERLQGANFFTKLDLRNAYHLVRIRAGDEWKSAFNTPRGHFEYCVLPFGLSNAPAVFQAFVNDVLRDMIDQFIYVYLDDILIFSHSLQEHVQHIRRVLQRLLENGLYVKAEKCVFHAQSVPFLGHIVSVEGLRMDPEKIKAVVNWPTPDSRKALQRFLGFANFYRRFIRNFSQLAAPLTALTS-SKTPFRWSSAAEAAFSKLKGCFVSAPILITPDPSRQFVVEVDASEVGVGAILSQRSSSDGKIHPCAYYSHRLSAAESNYDIGNRELLAVKLALEEWRHWLEGSGVPFIVWTDHKNLEYIKSAKR-LNSRQARWALFFGRFNFTISYRPGSKNIKPDALSRLFDSS------ERTSSLEPVVPKRIV-----------------ISNITWEIESK-VRAALDGVTPPIGCPPSRLFVPEKLRSDVIRWGHSSKVACHPGVSRTSFVIKQRFWWPALARDVRDFVLACSVCAVSKTSNRPPAGLLQPLSVPSRPWSHISLDFVTGLPPS-NGNTVILTVVDRFSKAAHFVPLPKLPSARETAVAVINHVFRIHGLPTDVVSDRGPQFISKFWREFCRLLGATVSLSSGFHPQSNGQTERANQDLERTLRCLVSQNP-SSWSQQLSWVEYAHNSLPVSATGLSPFQCSLG 1225          

Query: 2185 DKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEK-GHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGK--RFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGK---IKTRILTVTAEGGYNKWQNDNMEVQE-IKNKLENKDCKFIMENNTVLTKQGKIWIPSDNRQRMIKEVHV--LLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXX-XXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSK---YISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFG 4302
            + +E+ I +     IIR  +SP       V KK+   +R C+D+R LN IT +  +P+P +    + L G+ +F+ +DL NAY+ V +    + KTAF+T  G F +  +PFG++ AP  FQ L+  VL+D+    + VYLDDILIF+ + ++H     +VL ++   GL +  EKC    + V+FLGHI++ +G++ D  KI+A+ ++  P   K L+ FLG  N+YRRFI ++++ A  L S+   +    RW+   E AF ++K   ++AP+L+ PD  ++F+++ DAS   +GA+LSQ+    G  H  AY SH +SS E+ Y I  +ELLA+    + + H+L G    F++ TDHK + ++ + K+ + ++   W  +    +  + YR G+ +   D LSR         + +  D  +     +  RI+            N + E++  ++  L+          N       ++++P + R  +++  H   + CH G  +    ++       +A +V+  +  C  C   K+               + P+  I +D    L  + N    I  ++D +SK   +ISL  +    E  ++  +++      G P ++  D G  F ++  +E  +  G  +  SS +H  +NG  ER  + +   +   +++    +W+  +  +EY  N+     TG+S  +   G
Sbjct:  538 EAMEKYISDSLAAKIIRPSSSPAGAGFFFV-KKKDGSLRPCIDYRGLNSITVKNTYPLPLMSSAFERLQGANFFTKLDLRNAYHLVCIRPGDEWKTAFNTPRGHFEYCVLPFGLSNAPAVFQALVNDVLRDMIDQFIYVYLDDILIFSHSLQEHIQHVRRVLQRLLENGLYVKAEKCVFHAQSVQFLGHIVSVEGMRMDPEKIQAVVNWPTPDSRKALQRFLGFANFYRRFIHNFSQLAAPLTSLT-SSKTPFRWSSAAEAAFSKLKGCFVSAPILIAPDPSRQFVVEVDASEVGVGAILSQRSASDGKVHPCAYFSHRLSSAERNYDIGNRELLAVKLALEEWRHWLEGSGVPFIVWTDHKNLEYIKSAKR-LNSRQARWALFFGRFNFTISYRPGSKNIKPDALSR---------LFDPSDRTSSPDPVLPQRIVVA----------NISWEIESRVRTALDGVTPPIGCPPN-------RLFVPEELRSDVVRWGHSSKVACHPGVSRTLFVVKQRFWWPAMARDVRDFVLACSVCAVSKSSNRPPAGLLQPLSVPSRPWSHISLDFVTGLPSS-NGNTVILTVVDRFSKAAHFISLPKLPSARETAVA--VIDHVFRIHGLPTDVVSDRGPQFVSKFWREFCRLLGATVSLSSGFHPQSNGQTERANQDLERTLRCLVSQNP-SSWSQQLSWVEYAHNSLPVSATGLSSFQCSLG 1223          

Query: 2038 RLLEIFQANKNVFMADKWDIGCTNLIKHKI-ITKGEPIMIKPRR-QPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNE-----------KIR------------WTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAI-YYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLS---------------------RKTC-GTCVQCMMEHEDAKTG--------------KIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNTVL---------------------------TKQGKIWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK 4308
            RL +    +  +F  +  D+GC+   KHKI + + +P   + RR  P +LED + + ++ L+  GII++  SP+ +P+V V +K+   IR+C+D+R LN+ T    +  P +++ L+ L GS++FS +DL + YYQ+ +  E +EKTAF    G F FNRMP G+  AP TFQ LM + + D+    V+VYLDD+++F +T E+H     KV  ++   GL+L+PEKCQ  +  V ++GH+++ +GI TD +KIEA+ S+ KP+ +  LRSFLG C YYRRF+K ++K A+ L  +   N E           ++R            WTE C+KAF ++K  L  APVL + D  K + L  DAS + +G +L Q+  K     +A+ S ++S  E+ Y   + E LA+ +      + YLYG  F ++TD+  +T+++TT K + A    W+  L+     + YR G  + +AD LS                     R  C G   +C   +   K G               + T  +    +G   + Q+++   Q     L  K  + +  ++  L                           +++ ++ +P  +R  ++  +H    H G  K    +++      +  +V+    +C RC + KT+ ++    +       P + + +D    ++        +  + DHY++Y        Q   T+++ L+ ++ + +G PK +H D G++FE++ + EL    G+    ++PYH   +   ER  RT+ + +  +L +  + +W+  +  + +  N+T    TG SP  ++FGR+
Sbjct:  290 RLRKHLNEHSALFSRNDLDMGCSTSTKHKIRLREDKPFRERSRRIAPGDLED-LRKHLEELKAAGIIKESRSPYASPIVVV-RKKNGSIRMCVDYRTLNQRTIPDQYTTPRIEDALNCLVGSKWFSVLDLRSGYYQLPMHPEDKEKTAFICPLGFFEFNRMPQGLCGAPATFQRLMERTVGDMHLLEVLVYLDDLIVFGRTLEEHEQRLLKVFDRLEKEGLKLSPEKCQFCQPSVNYVGHVVSAEGIATDPSKIEAVSSWPKPRTITELRSFLGFCGYYRRFVKGFSKVAQPLNQLLQSNTEVEGSDRDILAKRLRGQGWTRESIEDFWTEECDKAFDQLKYCLTHAPVLAYADATKPYTLHIDASREGLGGILYQEYNK-ELRPVAFISRSLSPSERNYPAHKLEFLALKWAVVDKLHEYLYGAEFEVQTDNNPLTYILTTAK-LDATGHRWLAALAHYKFSLRYRPGRDNRDADGLSRRPHGDLHPDDEWIEIPAPGVRTMCQGITGRCQSGNFAEKIGMTVRGIPKLYCNVTSVGTSTMPALNKGDIKRDQSEDPLCQMAMEALRKKQVQILKTDSHPLASLLVKEWDRLRLRDGLVYRRAPSATDSEKWQLMLPQKHRDSVLMALHDEHGHLGYDKTLGLVRDRFYWPCMKQDVEDYCRSCLRCIQRKTLPSRAAPLSHMESH-SPLDLVCIDFLS-IEPDEGGTSNVLVVTDHYTRYAQAFPTKDQRAITVAKVLVERFFIHYGLPKRIHSDQGRDFESKLVHELMSMLGVLKSRTTPYHPQGDPQPERFNRTLLDML-GTLPKEKKTHWSRHIATVVHAYNSTKNGATGYSPYFLMFGRE 1128          

Query: 2011 DVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGE-PIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEK-IRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRK 3402
            D L ++   +L +I ++   +F A+    G T+  +HK+ T  + PI     R    +  +++  I  +   G+I   +SPW +P+V V KK+    R C+D+R+LN +T   A+PMP VDE+LD L  ++Y +++DL   Y+Q+ L   +QEK+AF T  G + F  MPFG+  AP TFQ L+ ++L+ + +D    YLDDI +F++T E+H     +V  +I  AGL L PEKC +   EV++LGH +    ++ D  K+EAI  +  PK  K + +FLG   YYR+FI +Y+  A+ L  +  +   + I WT  CE A   +K+AL ++PVL  PDF + FIL TDAS   +GAVLSQ +  G EH +AY S  +   E  Y    KE LAI +  +    YLYG+ F + TDH  ++++         +   W   L   +  +++RKG  H NAD LSR+
Sbjct:  295 DHLHLSQQDQLRKILRSYSPMFSANP---GRTHWAEHKVDTGTQLPIRSPAYRVAEAVRPEMKSQIDEMLAFGVITPSHSPWASPVVLVPKKDGS-TRFCVDYRRLNDVTTTDAYPMPRVDELLDRLGNAKYLTTLDLSRGYWQIPLAPSAQEKSAFLTPFGLYQFTVMPFGMRNAPATFQRLVNRLLEGM-QDFAQAYLDDIAVFSQTWEEHLQHLQRVFAQIQDAGLTLKPEKCHLAMAEVQYLGHRVGGGQLRPDPAKVEAICQWPIPKTQKQVLAFLGTSGYYRKFIPNYSTVAKPLTDLTSRQRSRTIVWTPECESAMNALKQALASSPVLAAPDFSRRFILQTDASNFGLGAVLSQVNTYGEEHPVAYLSRKLLPREAAYATIEKECLAIVWALQKLQPYLYGREFTVVTDHNPLSWLQRVSG-DNGKLLRWSLLLQQYNFTIQHRKGKEHHNADGLSRQ 754          

Query: 3916 IDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKI----DRMKWYSNKEINREDME---------KRIE----------------DKTLKPKISKTVRNFEMEDVVLIKQEIRNKDDARWEGPYKVIKKIHERSYLLKDQNGKMVVRNVEKIKHFK 4587
            +D+ ++Y    A+ K D  T+++ L+  +  + G P E+  D G  F ++ ++ L +  G+  I SSPYH  TNG+ ER   T++  +  +  E G K+W   +P + +      Q++TG SP E+++GR++    D +  Y       +++          +R+E                 K    + ++  R  E + V+L+     +K  A WEGPY V  K+H+ +Y         VV   E   H+K
Sbjct:    1 MDYATRYPEAVALRKIDAPTVADALIQIFS-RVGFPSEILSDQGPQFTSQLLQCLWQRCGVRAIHSSPYHPQTNGLCERFNGTLKTMLR-TFVESGEKDWERYLPHLLFAYREVPQESTGFSPFELLYGRRVRGPLDLLCEYWEGAPQSQEVPIIPYVLKFRQRLEQMTSLAHDHLSAAQQRQKVWYDRKARERRFMEGDKVLLLVPTRHDKLQAAWEGPYVVTHKLHDTTY---------VVTPPEDPSHYK 242          

Query: 2191 IEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKD--IRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEK-GHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKR--FVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNTVL--TKQGKIWIPSDNRQRMIKEVHVL--LCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXX-XXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKF-GAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYI--NASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGR 4305
            ++E I      G IR   SP       V   EKKD  +R C+D+R LNKIT +  +P+P + E+ D L G++ FS +DL  AY  +++ +  + KTAF+T++G + +  MPFG+  AP  FQE +  + +DL    V+VYLDDILIF++  E H +   + L ++    L    EKC     ++ FLG+II+  G + D  K+ AIQ +  P+  K ++ F+G  NYYR+FIK ++ +   + S+  K      W  +  +AF  +K+A I+A VL  P+    F ++ DAS    GA+LSQ+    G  H  AY S   SS E+ Y I  +ELLA+    + + H L G      + TDHK + F+ + K+    Q   W  + S     + YR GT +  AD LSR         +         +I   +L   AE                         + ++  +     T  G  ++P + R  ++++ H      H G++K  + +Q       +  +V+  +  C  C   K   ++           + P+  + MD    L  +      I  +ID +SK      + K         L  + I +  G P E+  D G  F +R  + L K+ G+ L FSS YH  TNG  ER  + + +++  + SL +    +W+D++P  E+  N     +TG SP   ++G+
Sbjct:   18 MKEYISENLQRGFIRPSTSPAGAGFFFV---EKKDGGLRPCIDYRGLNKITVKNRYPLPLISELFDQLKGAKIFSKLDLRGAYNLIRIREGDEWKTAFNTRDGHYEYLVMPFGLCNAPAVFQEFVNDIFRDLLGKSVVVYLDDILIFSQDLETHRSQVKEALSRLRENSLFAKLEKCTFEVPKISFLGYIISSRGFEMDPAKVSAIQKWPLPQSTKAIQRFIGFANYYRQFIKGFSSRIAPILSLIRKGGRPNCWPPVALEAFQSLKDAFISASVLRHPEPHLPFFIEVDASDVGAGAILSQRHSADGKLHPCAYFSKKFSSAEQNYDIGNRELLAVKLALEEWRHLLEGASHPVTIYTDHKNLEFLQSLKRQNPRQ-ARWSLFFSRFHFVLTYRPGTKNRKADALSRSFSPEDRLPIEREPIIPPSRIIASVLPQFAE-------------------------QILLSQSAAPPDTPIGMAFVPPELRLPILQQTHSSKQAGHPGSEKTLELLQRLVWWPTIRKDVRDFVAACTVCATTKASHSRPCGLLHPLPVPSRPWTHLGMDFIVELPPSCG-NTVIWVVIDRFSKMAHFVPLRKLPSAVELAQLFIQHIFRLHGFPVEIVSDRGSQFVSRFWRSLCKSLGVSLQFSSAYHPQTNGAAERVNQALEQFLRNHVSLCQ---DDWSDLLPWAEFAHNNARHSSTGRSPFLSVYGQ 702          

Query: 1624 LDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESLRC--------ANNSRLETMGKLNINVKMGSMERNVTFIIVKNLIPEIIGGVELQRLFGIELKYILEEHEKRSDFI---CEIEARFGRIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCT-NLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKD--IRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEK-GHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKR--FVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNTVL--TKQGKIWIPSDNRQRMIKEVHVL--LCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXX-XXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKF-GAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYI--NASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGR 4305
            L  Q   V   LD+GA  N M  +   ++  I +     S+R         + ++   T G+L++ +    +E+ ++F+I+      ++ G+   RL    + +   +  + S +    C I     R+            V +        ++F      F+       C  +L+   +  +G    + P      +++ I E   NL+  G IR   SP       V   EKKD  +R C+D+R LNKIT +  +P+P + E+ D L G++ FS +DL  AY  +++ +  + KTAF+T++G + +  MPFG+  AP  FQE +  + +DL    V+VYLDDILIF++  E H +   + L ++    L    EKC     ++ FLG+II+  G + D  K+ AIQ +  P+  K ++ F+G  NYYR+FIKD++ +   + S+  K      W  +  +AF  +K+A I+A VL  P+    F ++ DAS    GA+LSQ+    G  H  AY S   SS E+ Y I  +ELLA+    + + H L G      + TDHK + F+ + K+    Q + W  + S  +  + YR GT +  AD LSR         + +       +I   +L   AE                         + ++  +     T  G  ++P + R  ++++ H      H G++K  + ++       +  +V+  +  C  C   K   ++           + P+  + MD    L  +      I  +ID +SK      + K         L  + I +  G P E+  D G  F +R  + L K+ G+ L FSS YH  TNG  ER  + + +++  + SL +    +W+D++P  E+  N     +TG SP   ++G+
Sbjct:  347 LSSQAIPVSAFLDSGAAGNFMDLAFAKKV-GISLFPVTPSIRVFAIDDRPLSTDTITLTTGELSVQIGALHLEK-MSFLIIPCPSSPVVLGLPWLRLHNPSIDWSSGQISRWSQYCQRHCLIPQPLQRVTVSSTSFSALPSVYR-----DFSDVFCKKSAEFLPPHRRYDCPIDLLPGTMPPRGRTYPLSPAET-AAMKEYISE---NLQR-GFIRPSTSPAGAGFFFV---EKKDGGLRPCIDYRGLNKITVKNRYPLPLISELFDQLKGAKIFSKLDLRGAYNLIRIREGDEWKTAFNTRDGHYEYLVMPFGLCNAPAVFQEFVNDIFRDLLGKSVVVYLDDILIFSQDLETHRSQVKEALSRLRENFLFAKLEKCTFEVPKISFLGYIISSRGFEMDPAKVSAIQKWPLPQSTKAIQRFIGFANYYRQFIKDFSSRIAPILSLIRKGGRPNCWPPVALEAFQSLKDAFISASVLRHPEPHLPFFIEVDASDVGAGAILSQRHSADGKLHPCAYFSKKFSSAEQNYDIGNRELLAVKLALEEWRHLLEGASHPVTIYTDHKNLEFLQSLKRQNPRQAR-WSLFFSRFNFVLTYRPGTKNRKADALSRSFSPEDRLPIEQEPIIPPFRIIASVLPQFAE-------------------------QILLSQSAAPSDTPIGMAFVPPELRLPILQQTHSSKQAGHPGSEKTLELLRRLVWWPTIRKDVRDFVAACTVCATTKASHSRPCGLLHPLPIPSRPWTHLGMDFIVELPPSCG-NTVIWVVIDRFSKMAHFIPLRKLPSAVELAHLFIQHIFRLHGFPVEIVSDRGSQFVSRFWRSLCKSLGVSLQFSSAYHPQTNGAAERVNQALEQFLRNHVSLCQ---DDWSDLLPWAEFAHNNASHSSTGRSPFLSVYGQ 1220          

Query: 1624 LDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESLRC--------ANNSRLETMGKLNINVKMGSMERNVTFIIVKNLIPEIIGGVELQRLFGIELKYILEEHEKRSDFI---CEIEARFGRIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCT-NLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKD--IRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEK-GHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKR--FVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNTVL--TKQGKIWIPSDNRQRMIKEVHVL--LCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXX-XXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKF-GAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYI--NASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGR 4305
            L  Q   V   LD+GA  N M  +   ++  I +     S+R         + ++   T G+L++ +    +E+ ++F+I+      ++ G+   RL    + +   +  + S +    C I     R+            V +        ++F      F+       C  +L+   +  +G    + P      +++ I E   NL+  G IR   SP       V   EKKD  +R C+D+R LNKIT +  +P+P + E+ D L G++ FS +DL  AY  +++ +  + KTAF+T++G + +  MPFG+  AP  FQE +  + +DL    V+VYLDDILIF++  E H +   + L ++    L    EKC     ++ FLG+II+  G + D  K+ AIQ +  P+  K ++ F+G  NYYR+FIKD++     + S+  K      W  +  +AF  +K+A I+A VL  P+    F ++ DAS    GA+LSQ+    G  H  AY S   SS E+ Y I  +ELLA+    + + H L G      + TDHK + F+ + K+    Q + W  + +  +  + YR GT +  AD LSR         + +       +I   +L   AE                         + ++  +     T  G  ++P + R  ++++ H      H G++K  + ++       +  +V+  +  C  C   K   ++           + P+  + MD    L  +      I  +ID +SK      + K         L  + I +  G P E+  D G  F +R  + L K+ G+ L FSS YH  TNG  ER  + + +++  + SL +    +W+D++P  E+  N     +TG SP   ++G+
Sbjct:  347 LSSQAIPVSAFLDSGAAGNFMDLAFAKKV-GISLFPVTPSIRVFAIDDRPLSTDTITLTTGELSVQIGALHLEK-MSFLIIPCPSSPVVLGLPWLRLHNPSIDWSSGQISRWSQYCQRHCLIPQPLQRVTVSSTSFSALPSVYR-----DFSDVFCKKSAEFLPPHRRYDCPIDLLPGTMPPRGRTYPLSPAET-AAMKEYISE---NLQR-GFIRPSTSPAGAGFFFV---EKKDGGLRPCIDYRGLNKITVKNRYPLPLISELFDQLKGAKIFSKLDLRGAYNLIRIREGDEWKTAFNTRDGHYEYLVMPFGLCNAPAVFQEFVNDIFRDLLGKSVVVYLDDILIFSQDLETHRSQVKEALSRLRENFLFAKLEKCTFEVPKISFLGYIISSRGFEMDPAKVSAIQKWPLPQSTKAIQRFIGFANYYRQFIKDFSSHIAPILSLIRKGGRPNCWPPVALEAFQSLKDAFISASVLRHPEPHLPFFIEVDASDVGAGAILSQRHSADGKLHPCAYFSKKFSSAEQNYDIGNRELLAVKLALEEWRHLLEGASHPVTIYTDHKNLEFLQSLKRQNPRQAR-WSLFFTRFNFVLTYRPGTKNRKADALSRSFSPKDRLPIEQEPIIPPFRIIASVLPQFAE-------------------------QILLSQSAAPSDTPIGMAFVPPELRLPILQQTHSSKQAGHPGSEKTLELLRRLVWWPTIRKDVRDFVAACTVCATTKASHSRPCGLLHPLPIPSRPWTHLGMDFIVELPPSCG-NTVIWVVIDRFSKMAHFIPLRKLPSAVELAHLFIQHIFRLHGFPVEIVSDRGSQFVSRFWRSLCKSLGVSLQFSSAYHPQTNGAAERVNQALEQFLRNHVSLCQ---DDWSDLLPWAEFAHNNASHSSTGRSPFLSVYGQ 1220          

Query: 2326 NKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQ------FCFNRM----PFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQ-KDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAI 3192
            + +T+RQ +    V E+ D LHG+ +F+ ++L          KES+ +   +  E        F  ++M    PF + +       ++  +LKD+    V+ +  ++L+++ ++E+H     +VL +     +  + +K Q  R+  + LG  I+  G++ +   +  I     P   + L+S + +   YR F++++A  A  L      ++E   W E  ++A   +K A   +PVL  P  +  F L+TD +   + A L Q  DE G +   A+ S  +S+ E  Y      +L I
Sbjct:  898 DMLTDRQDYTQ-MVPELFDQLHGAAWFTKLELLGI-------KESEMRHTVTHTEDTWRASFGFGLHQMRCYRPFTMNSYSDEGNNIVHFILKDILGLFVICHGREVLVYSMSQEEHSQHVRQVLVRFRYHNIYCSLDKTQFHRQTAEILGFNISPKGVKLNKNLMNLIVGCPVPGSRRCLQSVIDLVYPYRHFVENFAVIAAPLVRQL-LSSEPYYWGEEEQEALESLKRAFRKSPVLYHPKPQNPFYLETDITGSFLSASLVQTDDETGKKSTCAFYSRPLSTMEVEYPRVEMRILPI 1188          

Query: 2326 NKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQ------FCFNRM----PFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQ-KDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAI 3192
            + +T+RQ +    V E+ D LHG+ +F+ ++L          KES+ +   +  E        F  ++M    PF + +       ++  +LKD+    V+ +  ++L+++ ++E+H     +VL +     +  + +K Q  R+  + LG  I+  G++ +   +  I     P   + L+S + +   YR F++++A  A  L      ++E   W E  ++A   +K A   +PVL  P  +  F L+TD +   + A L Q  DE G +   A+ S  +S+ E  Y      +L I
Sbjct:  898 DMLTDRQDYTQ-MVPELFDQLHGAAWFTKLELLGI-------KESEMRHTVTHTEDTWRASFGFGLHQMRCYRPFTMNSYSDEGNNIVHFILKDILGLFVICHGREVLVYSMSQEEHSQHVRQVLVRFRYHNIYCSLDKTQFHRQTAEILGFNISPKGVKLNKNLMNLIVGCPVPGSRRCLQSVIDLVYPYRHFVENFAVIAAPLVRQL-LSSEPYYWGEEEQEALESLKRAFRKSPVLYHPKPQNPFYLETDITGSFLSASLVQTDDETGKKSTCAFYSRPLSTMEVEYPRVEMRILPI 1188          

Query:  803 CWTCQKPGHSSRECNIKRRFQCYACGVEGHIRRECPTIKCHRCNARGHKERECYTNME 976
            C+ C +PGH +R+CN +   +CY CG  GHI+++C  IKC+RC   GH    C    E
Sbjct:   91 CYICSQPGHLARDCNRQEEQKCYTCGEFGHIQKDCTQIKCYRCGENGHMAVNCSKTSE 148          

Query:  803 CWTCQKPGHSSRECNIKRRFQCYACGVEGHIRRECPTIKCHRCNARGH 946
            C+ C KPGH +R+C+     +CY+CG  GHI+++C  +KC+RC   GH
Sbjct:   99 CYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGH 146          

Query:  803 CWTCQKPGHSSRECNIKRRFQCYACGVEGHIRRECPTIKCHRCNARGH 946
            C+ C KPGH +R+C+     +CY+CG  GHI+++C  +KC+RC   GH
Sbjct:   98 CYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGH 145          

Query: 1633 QGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESLRCANNSRLETMGKLNINVKMGSMERNVTF-----------------IIVKNLIPEIIGGVELQR----LFGIELKYILEEHEKRSDFICEIEARFGRIITDEERLRHA------IDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKI-ITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKD----IRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCE--KAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSR-----KTCGTCVQCMMEHEDAK--------TGKIKTRILTVTAE-----------GGYNKWQNDNMEVQEIKNKLENKDCKFIMENNTV---------LTKQGKIWIPSDNRQRMIKEVHVL-------------------LCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEP-FEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGI--IERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQK-TTGVSPAEIIF 4299
            +GR   CLLDTG+ IN++        ENI  L  + S RC     L + G + +N  +  + RN  F                 +I + L+      +  +     LF    K I  E E+  +   +         +D+E ++        +D L      +L  +    +N+   +   +  TN IKH +  T   PI  K        E ++E  ++ + N G+IR+ NSP+N+P   V KK         R+ +D+R+LN+IT    +P+PN+DEIL  L   +YF++IDL   ++Q+++D+ES  KTAFSTK G + + RMPFG+  AP TFQ  M  +L+ L     +VYLDDI+IF+ +  +H N    V  K+A A L+L  +KC+  +KE  FLGHI+  DGI+ +  K++AI S+  P   K +R+FLG+  YYR+FI +YA  A+ + S C K   KI  T+  E  +AF ++K  +I  P+L  PDF K+F+L TDAS   +GAVLSQ       H I++ S  ++ HE  Y    KELLAI +  K F HYL G++F++ +DH+ + ++   K+P  A+ + W   LS    K++Y KG  ++ AD LSR            Q   E +++             K +I+ + ++                 Q D M +++ K  L +    FI  N T+         + ++  I I +    ++I+ + +L                   L H G QK+TK  + N    N    ++ +I  C  C   KT    TK   +   + E   EK  +DI        ++ K+    ID YSK+ +L  I  +D       L+ +   + G PK L  D    F + ++K   +   +EL  ++      NG+  +ER  +TI E I    +    +     +  I YT N  ++  TTG  PA+I  
Sbjct:   21 KGRSYKCLLDTGSTINMIN-------ENIFCLPIQNS-RC---EVLTSNGPITLN-DLIMLPRNSIFKKTEPFYVHRFSNNYDMLIGRKLLKNAQSVINYKNDTVTLFDQTYKLITSESERNQNLYIQRTPE-SIASSDQESIKKLDFSQFRLDHLNQEETFKLKGLLNKFRNLEYKEGEKLTFTNTIKHVLNTTHNSPIYSKQYPLAQTHEIEVENQVQEMLNQGLIRESNSPYNSPTWVVPKKPDASGANKYRVVIDYRKLNEITIPDRYPIPNMDEILGKLGKCQYFTTIDLAKGFHQIEMDEESISKTAFSTKSGHYEYLRMPFGLRNAPATFQRCMNNILRPLLNKHCLVYLDDIIIFSTSLTEHLNSIQLVFTKLADANLKLQLDKCEFLKKEANFLGHIVTPDGIKPNPIKVKAIVSYPIPTKDKEIRAFLGLTGYYRKFIPNYADIAKPMTS-CLKKRTKID-TQKLEYIEAFEKLKALIIRDPILQLPDFEKKFVLTTDASNLALGAVLSQNG-----HPISFISRTLNDHELNYSAIEKELLAIVWATKTFRHYLLGRQFLIASDHQPLRWLHNLKEP-GAKLERWRVRLSEYQFKIDYIKGKENSVADALSRIKIEENHHSEATQHSAEEDNSNLIHLTEKPINYFKKQIIFIKSDKNKVEHSKIFGNSITTIQYDVMTLEKAKQILLD---HFIHRNITIYIESDVDFEIVQRAHIEIVNTTYTKVIRSLFLLKNVGSYAEFKEIILQSHEKLLHPGIQKMTKLFKENHFFPNSQLLIQNIINECNICNLAKTEHRNTKMPLKITPNPEHCREKFVVDIYS------SEGKHYISCIDIYSKFATLEQIKTKDWIECRNALM-RIFNQLGKPKLLKADRDGAFSSLALKRWLEEEEVELQLNTA----KNGVADVERLHKTINEKIRIINSSDDEEVKLSKIETILYTYNQKIKHDTTGQRPAQIFL 964          

Query: 1606 GRPS-TTLDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESLRCAN-----NSRLETMGKLNINVK----MGSMERNVTFIIVKNLIPEIIGGVELQ----RLFGIELKYI--LEEHEKR--------SDFICEIEARFGRII-TDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKE----KKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEM-CEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSR 3399
            G+P   T+  +   + CL+DTG+ +N+ +K++ D    + I  T   +  +N     N  +    K+         +     N   ++ + L+ E    +  +     L+  + K I  +  HE+          D +     +   I+ +D  RL H    L     +RL  + Q   ++   +   +  TN  KH I TK    +      P   E ++E  I+++ N GIIR  NSP+N+P+  V KK+    K+  R+ +D+R+LN+IT     P+PN+DEIL  L    YF++IDL   ++Q+++D ES  KTAFSTK G + + RMPFG+  AP TFQ  M  +L+ L     +VYLDDI++F+ + ++H    G V  K+A A L+L  +KC+  ++E  FLGH++  DGI+ +  KIEAIQ +  P   K +++FLG+  YYR+FI ++A  A+ + + C K N KI  T    + AF ++K  +   P+L  PDF K+F L TDAS   +GAVLSQ       H ++Y S  ++ HE  Y    KELLAI +  K F HYL G+ F + +DH+ ++++   K P  ++   W   LS  D  ++Y KG  +  AD LSR
Sbjct:   11 GKPQYITIKYKENNLKCLIDTGSTVNMTSKNIFD----LPIQNTSTFIHTSNGPLIVNKSIIIPSKILFPTTNEFLLHPFSENYDLLLGRKLLAEAKATISYRDQEVTLYNNKYKLIEGIATHEQSHFQNVNMIPDTMLRQPNKISPILESDLYRLEH----LNNEEKQRLCALLQKYHDIQYHEGDKLTFTNQTKHTINTKHNLPLYSKYSYPQAYEQEVESQIQDMLNQGIIRTSNSPYNSPIWVVPKKQDASGKQKFRIVIDYRKLNEITVGDRHPIPNMDEILGKLGRCNYFTTIDLAKGFHQIEMDPESVSKTAFSTKHGHYEYLRMPFGLKNAPATFQRCMNDILRPLLNKHCLVYLDDIIVFSTSLDEHLQSLGLVFEKLAKANLKLQLDKCEFLKQETTFLGHVLTPDGIKPNPEKIEAIQKYPIPTKPKEIKAFLGLTGYYRKFIPNFADIAKPM-TKCLKKNMKIDTTNPEYDSAFKKLKYLISEDPILKVPDFTKKFTLTTDASDVALGAVLSQDG-----HPLSYISRTLNEHEINYSTIEKELLAIVWATKTFRHYLLGRHFEISSDHQPLSWLYRMKDP-NSKLTRWRVKLSEFDFDIKYIKGKENCVADALSR 623          

Query: 2113 IKHKIITKGEPIMIKPRRQPINLEDKIEEAI----KNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALE-SICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGH-EHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRK----TCGTCVQCMMEHEDA--KTGKIKTRILTVTAE-GGYNKWQNDNMEVQEIKNKLENKDC---KFIMENNTVLTKQGKIWIPSDNRQRMIKEVH---VLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEP-FEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKF-GAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKIDRMKWYSNKEINRE-----DMEKRIEDKTLKPKISKTVRNFEME---------------DVVLIKQEIRNKDDAR------WEGPYKVIKKIHERSYL--LKDQNGKMVVRNVEKIKHF 4584
            +KH I  K  P    PR QP ++ +K E+ I    + L +N  I    SP ++P+V V KK+    RLC+D+R LNK T    FP+P +D +L  +  ++ F+++DL + Y+Q+ ++ + + KTAF T  G++ +  MPFG+  AP TF   M    +DL    V VYLDDILIF+++ E+H+     VL ++    L +  +KC+   +E +FLG+ I    I     K  AI+ F  PK VK  + FLG+ NYYRRFI + +K A+ ++  IC K+    +WTE  +KA  ++K+AL  +PVLV  + +  + L TDAS D IGAVL + D K     V+ Y S ++ S +K Y     ELL I     HF + L+GK F LRTDH ++  +    +P   + Q W++ L++ D  +EY  G  +  AD +SR     T  T      E   +  K+  + + +L    E   +N    D    +  + KLE  +     + +E+  +   Q ++ +P   +  +++  H   +   H G       I        L   + + I  C +CQ +K+   +     Q +   E  +  I MD    L  T N    I  ++D +SK     A  K  + T    LL ++I  + G P+ +  D      A   +EL K  GI+   SS  H  T+G  ER  +T+   + A  +    +NW   +P+IE+  N+T  +T G SP EI  G   +     S+ E+N       ++ K ++  T++ K        EME               D VL+ ++   K  A       + GP++V+KKI++ +Y   L     K  V NV+ +K F
Sbjct:  584 VKHDIEIK--PGARLPRLQPYHVTEKNEQEINKIVQKLLDNKFIVPSKSPCSSPVVLVPKKDGT-FRLCVDYRTLNKATISDPFPLPRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDL--RFVNVYLDDILIFSESPEEHWKHLDTVLERLKNENLIVKKKKCKFASEETEFLGYSIGIQKIAPLQHKCAAIRDFPTPKTVKQAQRFLGMINYYRRFIPNCSKIAQPIQLFICDKS----QWTEKQDKAIDKLKDALCNSPVLVPFNNKANYRLTTDASKDGIGAVLEEVDNKNKLVGVVGYFSKSLESAQKNYPAGELELLGIIKALHHFRYMLHGKHFTLRTDHISLLSLQNKNEP-ARRVQRWLDDLATYDFTLEYLAGPKNVVADAISRAVYTITPETSRPIDTESWKSYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYY-QDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNI-QNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKF 1444          

Query: 2113 IKHKIITKGEPIMIKPRRQPINLEDKIEEAI----KNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALE-SICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGH-EHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRK----TCGTCVQCMMEHEDA--KTGKIKTRILTVTAE-GGYNKWQNDNMEVQEIKNKLENKDC---KFIMENNTVLTKQGKIWIPSDNRQRMIKEVH---VLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEP-FEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKF-GAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKIDRMKWYSNKEINRE-----DMEKRIEDKTLKPKISKTVRNFEME---------------DVVLIKQEIRNKDDAR------WEGPYKVIKKIHERSYLL 4530
            +KH I  K  P    PR QP ++ +K E+ I    + L +N  I    SP ++P+V V KK+    RLC+D+R LNK T    FP+P +D +L  +  ++ F+++DL + Y+Q+ ++ + + KTAF T  G++ +  MPFG+  AP TF   M    +DL    V VYLDDILIF+++ E+H+     VL ++    L +  +KC+   +E +FLG+ I    I     K  AI+ F  PK VK  + FLG+ NYYRRFI + +K A+ ++  IC K+    +WTE  +KA  ++K AL  +PVLV  + +  + L TDAS D IGAVL + D K     V+ Y S ++ S +K Y     ELL I     HF + L+GK F LRTDH ++  +    +P   + Q W++ L++ D  +EY  G  +  AD +SR     T  T      E   +  K+  + + +L    E   +N    D    +  + KLE  +     + +E+  +   Q ++ +P   +  +++  H   +   H G       I        L   + + I  C +CQ +K+   +     Q +   E  +  I MD    L  T N    I  ++D +SK     A  K  + T    LL ++I  + G P+ +  D      A   +EL K  GI+   SS  H  T+G  ER  +T+   + A ++    +NW   +P+IE+  N+T  +T G SP EI  G   +     S+ E+N       ++ K ++  T++ K        EME               D VL+ ++   K  A       + GP++V+KKI++ +Y L
Sbjct:  610 VKHDIEIK--PGARLPRLQPYHVTEKNEQEINKIVQKLLDNKFIVPSKSPCSSPVVLVPKKDGT-FRLCVDYRTLNKATISDPFPLPRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDL--RFVNVYLDDILIFSESPEEHWKHLDTVLERLKNENLIVKKKKCKFASEETEFLGYSIGIQKIAPLQHKCAAIRDFPTPKTVKQAQRFLGMINYYRRFIPNCSKIAQPIQLFICDKS----QWTEKQDKAIEKLKAALCNSPVLVPFNNKANYRLTTDASKDGIGAVLEEVDNKNKLVGVVGYFSKSLESAQKNYPAGELELLGIIKALHHFRYMLHGKHFTLRTDHISLLSLQNKNEP-ARRVQRWLDDLATYDFTLEYLAGPKNVVADAISRAIYTITPETSRPIDTESWKSYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYY-QDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYVSTNI-QNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYEL 1450          

Query: 2068 NVFMADKWDIGCTNLIKHKI-ITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKK-----EKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKT 3405
            ++F  +   I   NL K ++ +   EP+  K  R P +  ++I+  ++ L  + I+    S +N+PL+ V KK     +KK  RL +D+RQ+NK      FP+P +D+ILD L  ++YFS +DL + ++Q++LD+ S++ T+FST  G + F R+PFG+  AP +FQ +MT     +      +Y+DD+++   +E+       +V GK     L+L+PEKC  F  EV FLGH     GI  D+ K + IQ++  P    + R F+  CNYYRRFIK++A  +R +  +C K N    WT+ C+KAF  +K  LI   +L +PDF KEF + TDAS    GAVL+Q +  GH+  +AY S A +  E     T +EL AI++   HF  Y+YGK F ++TDH+ +T++ +   P +   +  +  L   +  +EY KG  +  AD LSR T
Sbjct:  288 DIFALESEPITVNNLYKQQLRLKDDEPVYTKNYRSPHSQVEEIQAQVQKLIKDKIVEPSVSQYNSPLLLVPKKSSPNSDKKKWRLVIDYRQINKKLLADKFPLPRIDDILDQLGRAKYFSCLDLMSGFHQIELDEGSRDITSFSTSNGSYRFTRLPFGLKIAPNSFQRMMTIAFSGIEPSQAFLYMDDLIVIGCSEKHMLKNLTEVFGKCREYNLKLHPEKCSFFMHEVTFLGHKCTDKGILPDDKKYDVIQNYPVPHDADSARRFVAFCNYYRRFIKNFADYSRHITRLC-KKNVPFEWTDECQKAFIHLKSQLINPTLLQYPDFSKEFCITTDASKQACGAVLTQ-NHNGHQLPVAYASRAFTKGESNKSTTEQELAAIHWAIIHFRPYIYGKHFTVKTDHRPLTYLFSMVNPSSKLTRIRLE-LEEYNFTVEYLKGKDNHVADALSRIT 736          

Query: 3673 HAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKIDRMKWYSNKE-----INREDMEK----RIE------DKTLKPKISKTVRNFEME---------DVVLIKQEIRNKDDARWEGPYKVIKKIHERS--YLLKDQNGKMVVRNVEKIKHF 4584
            H G  K    ++ +   +N++  +K+ +  C++CQK KT        T T      F+++ +D  GPL ++ N  +Y   +I   +KY+    I  +  +T+++ +   +ILK+G  K    D G  ++   I +L K   I+ I S+ +HH T G++ER  RT+ EYI + ++   + +W   +    Y  N T        P E++FGR  +  K ++         N +D  K    R+E       K L+    K   N++++         D VL++ E+ +K D ++ GPYK I+ I + +   LL ++N K +V   +++K F
Sbjct:  909 HTGITKTLAKVKRHYYWKNMSKYIKEYVRKCQKCQKAKTTKHTKTPMTITETPEHAFDRVVVDTIGPLPKSENGNEYAVTLICDLTKYLVAIPIANKSAKTVAKAIFESFILKYGPMKTFITDMGTEYKNSIITDLCKYLKIKNITSTAHHHQTVGVVERSHRTLNEYIRSYIS-TDKTDWDVWLQYFVYCFNTTQSMVHNYCPYELVFGRTSNLPKHFNKLHSIEPIYNIDDYAKESKYRLEVAYARARKLLEAHKEKNKENYDLKVKDIELEVGDKVLLRNEVGHKLDFKYTGPYK-IESIGDNNNITLLTNKNKKQIVHK-DRLKKF 1235          

Query: 1612 PSTTLDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRE-SLRCANNSRLETMGKLNINVKMGSMERNVTFIIVKNLI-PEIIG--------------GVELQRLFGIELKYILE-EHEKRSDFICEIEARFGRIITDEERL---------------RHAIDVLKVTGNKR--LLEIFQANKNVFMADKWDIGCTNLIKHKIITKG-EPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDL-WKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKN--------KLENKDCKFI----MENNTVLTKQGKI---WIPSDN----------RQR---MIKEVH--VLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYI-NASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKI----------------DRMKWYSNKEINREDMEKRIEDKTLKPKISKTVRN-------------FEMEDVVLIKQEIRNKDDARWEGPYKVIKKIHERSYLLKDQNGK--MVVRNVEKIKHF 4584
            PS    + G ++  LLD+GA ++V+  S   +    E L+    S+   +  R+   G+  + +++GS    +   IV++L+ P I+G                E+    G  ++ + E  H  R    C       R ++ EE +               R  +D  + +   R  L  + +         + D+G T+L++H+I T G +P+ + PRR P    + ++  I+ + + G+I   + PW++P+V V KK+    R C+D+R+LN +T   A P+P +D+ LD L G+++FS++DL + Y+QV++ +E +EKTAFST  G F F  MPFG+  AP TFQ LM K L+ L WK   +VYLDDI++F KTEE+H      VL ++ + GL++ PEKCQ+ R+ V +LGH++ + GI TD  K  A+Q +  P+CV+ +R FLG+ +YYRRF++++A  A  L ++  K  EK  W    E+AF  +K+AL++ P+L  PDF + F+LD DAS D +GAVLSQ+ E+    VIAY S ++S  E+GYC TR+E+LA+ +  +HF  YLYG+RF+ RTDH ++ ++ + ++P   Q   W+  L+  D ++ +R G  H NAD LSR+    C QC ME   A   ++    + + A     +WQ  + E+Q+I+         +   +  + +     + + ++ ++G I   W   D           RQR   ++  VH      H G  K    ++          +V+     CE C      T K +   Q      PF+++ MD+ GPL+ET N  +YI    D++SK+    A+   + RT++  L+N    ++GAP+ LH D G+NFE+  +KE+ +  G+    ++ YH  ++G++ER  RT+ + +  AS++     +W   +  +     ++V  TTG +P+ +IFGR++                + +  Y+ +   R+D+E+  E  T++ K  +  R              +E  D V ++   + K  A W+GPY+V KK+   +Y +K   G+   +V + +++K +
Sbjct:  386 PSVAGKLNGLEIPLLLDSGAVVSVVPLSTWHKSTGGEPLKAAGGSILLGDGRRVRLCGQGTLPLQLGSWRGRLHVAIVESLVVPGILGTNFLDQYVKLIDWQAGEMTMTDGSSVRIVHEPSHATRPGIGCTWITASPREVSREETVGERPGNNSGELGACERALVDRAECSAQNRRALRSLIRRYGKAISCGEGDLGRTSLVQHRIETGGAQPVKLPPRRLPQAQRETVDRLIREMLHAGVIEPASGPWSSPVVLVRKKDGSP-RFCVDYRRLNAVTRVDAQPIPRIDDTLDALAGAKWFSTLDLASGYWQVEVAEEDREKTAFSTPLGLFQFRVMPFGLCNAPATFQRLMEKALRGLTWKT-CLVYLDDIIVFGKTEEEHLERLEGVLSRLQSVGLKIKPEKCQLMRQSVHYLGHVVTQQGIGTDPEKTAAVQKWPTPRCVREVRQFLGLASYYRRFVRNFAGVANPLHALT-KKGEKWHWGPKEEEAFTLLKKALVSPPILGHPDFDRTFLLDVDASEDAVGAVLSQQGERDPPSVIAYASRSLSRAERGYCATRREMLALVWATQHFRPYLYGRRFIARTDHNSLRWLRSFREP-EGQVARWLERLAEFDFEVVHRAGRKHQNADALSRR---VCKQCGMEGSPA---EVPVGAVKLDAASPIKQWQESDKELQQIREWSTQRTWPRAAPEGSRLLRSLWAQRDRIVVREGTICRKWETPDTGETRLLQVIPRQRIPEILAAVHNGQSGAHLGVAKTLAKLRQRYYWPQQREDVEDWCRACETCAARAVPTKKPQAPMQLQPVGYPFQRVGMDLLGPLEETRNGNRYILVACDYFSKWPEAFALPNAEARTVAAALVNGLFCRYGAPETLHSDQGRNFESALVKEVCQLFGVAKTRTTAYHPQSDGLVERMNRTLLDLLAKASIDHP--DDWDAHLDRVLLAYRSSVHHTTGATPSRVIFGREMRLPVDLVYGLPENAPEESVGEYTRR--LRQDLEQLYE--TVRGKAGREQRRQKFWKDRKAHGPVYEPGDQVWMQVPEKTKLGAYWDGPYEVQKKLDWNTYRVKQMKGRRQRLVVHFDRLKPY 1458          

Query: 1612 PSTTLDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRE-SLRCANNSRLETMGKLNINVKMGSMERNVTFIIVKNLI-PEIIG--------------GVELQRLFGIELKYILE-EHEKRSDFICEIEARFGRIITDEERL---------------RHAIDVLKVTGNKR--LLEIFQANKNVFMADKWDIGCTNLIKHKIITKG-EPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDL-WKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKN--------KLENKDCKFI----MENNTVLTKQGKI---WIPSDN----------RQR---MIKEVHVLLC--HAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYI-NASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKI----------------DRMKWYSNKEINREDMEKRIEDKTLKPKISKTVRN-------------FEMEDVVLIKQEIRNKDDARWEGPYKVIKKIHERSYLLKDQNGK--MVVRNVEKIKHF 4584
            PS    + G ++  LLD+GA ++V+  S+  +    E LE    S+   +  R+   G+  + +++GS    +   IV++L+ P I+G                E+    G  ++   E  H  R    C       R ++ EE +               R  +D  + +   R  L  + +         + D+G T+L++H+I T G +P+ + PRR P    + ++  I+ + + G+I   + PW++P+V V KK+    R C+D+R+LN +T   A P+P +D+ LD L G+++FS++DL + Y+QV++ +E +EKTAFST  G F F  MPFG+  AP TFQ LM K L+ L WK   +VYLDDI++F KTEE+H      VL ++ + GL++ PEKCQ+ R+ V +LGH++ + GI TD  K  A+Q +  P+CV+ +R FLG+ +YYRRF++++A  A  L ++  K  EK  W    E+AF  +K+AL++ P+L  PDF + F+LD DAS D +GAVLSQ+  +    VIAY S ++S  E+GYC TR+E+LA+ +  +HF  YLYG+RF+ RTDH ++ ++   ++P   Q   W+  L+  D ++ +R G  H NAD LSR+    C QC +E     T ++    + + A     +WQ  + E+Q+I+         +   +  + +     + + ++ ++G I   W   D           RQR   ++  VH      H G  K    ++          +V+     CE C      T K +   Q      PF+++ MD+ GPL+ET N  +YI  + D++SK+    A+   + RT++  L++    ++GAP+ LH D G+NFE+  +KE+ +  G+    ++ YH  ++G++ER  RT+ + +  AS++     +W   +  +     ++V  TTG +P+ IIFGR++                + +  Y+ +   R+D+E+  E  T++ K  +  R              +E  D V I+   + K  A W+GPY+V KK+   +Y +K+  G+   +V + +++K +
Sbjct:  346 PSVAGKLNGFEISLLLDSGAVVSVVPLSIWHKSTGGEPLEAAGGSILLGDGRRVRLCGQGTLPLQLGSWRGRLHVAIVESLVVPGILGTNFLDQYVKLIDWQAGEMTMTDGSSVRIAHEPSHATRPGIGCTWITAGPREVSREETVGERPGNDSGELGACERALVDRAECSAQNRRTLRSLIRRYGKAISCGEGDLGRTSLVQHRIETGGAQPVKLPPRRLPQAQRETVDRLIREMLHAGVIEPASGPWSSPVVLVQKKDGSP-RFCVDYRRLNAVTRVDAQPIPRIDDTLDALAGAKWFSTLDLASGYWQVEVAEEDREKTAFSTPLGLFQFRVMPFGLCNAPATFQRLMEKALRGLTWKT-CLVYLDDIIVFGKTEEEHLERLEGVLSRLQSVGLKIKPEKCQLMRQSVHYLGHVVTQQGIGTDPEKTAAVQKWPTPRCVREVRQFLGLASYYRRFVRNFAGVANPLHALT-KKGEKWHWGPKEEEAFTLLKKALVSPPILGHPDFDRTFLLDVDASEDAVGAVLSQQGGQDPPSVIAYASRSLSRAERGYCATRREMLALVWATQHFRPYLYGRRFIARTDHNSLRWLRNFREP-EGQVARWLERLAEFDFEVVHRAGRKHQNADALSRR---VCKQCGLE---GSTAEVPVGAVRLDAANPIKQWQESDKELQQIREWSTQRTWPRAAPEGSRLLRSLWAQRDRIVVREGTICRKWETPDTGETRLLQVIPRQRIPEILAAVHNGQSGGHLGVAKTLAKVRQRYYWPQQREDVEDWCRACETCAARAVPTKKPQAPMQLQPVGYPFQRVGMDLVGPLEETRNGNRYILVVCDYFSKWPEAFALPNAEARTVAAALVDGLFCRYGAPETLHSDQGRNFESALVKEVCQLFGVAKTRTTAYHPQSDGLVERMNRTLLDLLAKASIDHP--DDWDAHLNRVLLAYRSSVHHTTGATPSRIIFGREMRLPVDLVYGLPENTPEESVGEYTRR--LRQDLEQLYE--TVRGKAGREQRRQKFWKDRKAHGPVYEPGDQVWIQVPEKTKLGAYWDGPYEVQKKLDWNTYRVKEMKGRRQRLVVHFDRLKPY 1418          

Query: 2065 KNVFMADKWDIGCTNLIKHKIITKGEP-IMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCG-TCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIME---------------------------------NNTVLTKQ-----GKIW-----IPSDNRQRMIKEVHVLLC--HAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKIDRMK----------WYSNKEINREDMEKRIEDKTLKPKISKTVRNFEMEDVVLIKQEIRNKDDAR------------------------------WEGPYKVIKKIHERSY-LLKDQNGKMVVRNVEKIKHFKK 4590
            ++VF     D+G T+L +H+I T   P I   PRR PI  ++++   +K+++ + +I    SPW +P+V V KK+    R C+D+R+LN++T++ ++P+P +D+ILD L GS++FS++DL + Y+QV++  + +EKTAF+T +G + F  MPFG+  AP TF+ LM  VLK L  +  ++YLDDI+I  K+ E+H     KVL K+  A L+L+P KC++FR+EV +LGH+I+ +G++TD  K+ A++ +++P+ V  LRSFLG+C YYRRF+KD++  AR L  +  ++ +K  WT+ CE AF  +KEAL +AP+L +P   + FILDTDAS +++GAVLSQ+ E G E V+AY S  +S  E+ YC+TRKELLAI    +HF+HYLYG++F+LRTDH ++ +++  K P   Q   WI  L   DI + +RKG SH NAD LSR+ C   C  C       +      R +T +     + W +  +     K++L+++D K I+E                                  N VL ++     GK +     +P      ++KE+H      H G  K  + ++      N   +V+K    C+ C   K    +++ + Q      PFE+I  DI GPL  T +  KYI   ID+++K+     I  Q+  T++E ++  WI +FG P +LH D G+NF +  +KEL K  GI+   ++P H  ++G++ER  RTI   ++  ++   +++W   +P       + V +TTG SP++++FGR + R+             S+ E   +D++ R E           + NF  E V L  ++++ + D R                              W+GPY V+ ++++    + K  N K  V + ++++  KK
Sbjct:  643 QDVFSRSSSDVGRTSLTQHRIDTGDHPPIKQHPRRLPIAKQEEVRALLKDMQESNVIEPSASPWASPIVLVRKKDGS-TRFCVDYRRLNEVTKKDSYPLPRIDDILDTLSGSKWFSTLDLKSGYWQVEIHPDDREKTAFTTGQGLWQFKVMPFGLCNAPATFERLMETVLKGLSYEACLIYLDDIIIVGKSFEEHLENLRKVLQKLKEANLKLSPAKCKLFRQEVTYLGHVISAEGVRTDPEKVSAVKDWRRPENVHQLRSFLGLCTYYRRFVKDFSSIARPLHKLT-ESKQKFVWTKECENAFKNLKEALTSAPILTYPQLDRPFILDTDASNESVGAVLSQEIE-GQERVVAYWSKCLSKPERNYCVTRKELLAIVKAVEHFHHYLYGRKFLLRTDHASLAWLLNFKNP-EGQIARWIQRLQEYDITIRHRKGQSHGNADALSRRPCPENCRYCSRVEAKYQLVNPVARQITASTLADPDPWTDKEIR----KDQLQDRDIKPIIELMETSNRKPTWQDISSYSPTTKQYWALWDSLHIRNGVLYRKFESDDGKTFRWQLVLPRSRIPDVLKELHSSPAGGHFGIMKTLQRVRERFYWNNAKDDVQKWCRTCDACVSRKGPKKRSRGKLQRYNVGAPFERIAFDILGPLPRTADGNKYILVAIDYFTKWPEAYPIPDQEAVTVAEMMIQHWISRFGVPLQLHSDQGRNFTSAVVKELCKLLGIDKTQTTPLHPQSDGMVERFNRTILNNLSLVVSR-NQQDWDKKLPLFLLAYRSAVHETTGYSPSQMLFGRDL-RLPCDLLFGRPPDAPSSPEEYIQDLQARFE----------VMHNFARERVNLATEKMKTRYDTRATGHRFNEGDKVWLWNPTRRKGLSPKLQSPWDGPYTVLNRLNDVVVRIRKSSNSKPKVVHYDRLQARKK 1552          

Query: 1630 IQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRE-SLRCANNSRLETMGKLNINVKMG-SMERNVTFIIVKNLI-PEIIGGVELQR------LFGIELKYILEEHEKRSDFICEIEARFGRIITDEER-LRHAIDVLKVTG--------NKRLLEIFQANKNVFMADKWDIGCTNLIKHKIIT-KGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCK--------------FIMENNTVLTKQG---KIW-------------IPSDNRQRMIKEVHVLLC--HAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKIDRMKWYSNKEIN-REDMEKRIEDKTLKPKIS 4401
            I GR  +  +DTGA +++M+  + + ++  ++L  +   L  A    L  +G   +N+ +G S   + T ++  +L  P +IG   L++           L+    E + ++D + E       + T++ R     ID +  +G         ++L ++F   K V      D+G T++++H+I T   +PI + PRR P      I++ +  +   G+I + +SPW+ P+V   KK+    R C+D+R+LN  TE+   P+P +D+ LDIL GSR+FS++DL + Y+QV+++ E + KTAFST  G + F  MPFG+  AP TFQ LM +VL+ L     +VYLDDI+IF +T  +      +VL ++  AGL++ P KC++  +EV FLGH+++  GI TD  K   +++++ P+C   LR F+G+ +YYR+F+K++A  A  L  +  K +++  W + CE+AF EMK  L+TAP+L FPDF K F+LD DAS D +GAVLSQ  + G EH IAY S A++  E+ YC TR+ELLA+ +  KHF  YLYG RF +RTDH  + ++   ++P   Q   W+  L+  D+++ +R G  H NAD LSR+TCG C + ++    A+    + +    TA       QN + +++ +K  +  +DC               F  + N ++   G   ++W             +PS  R+ +++E+H      H G ++  +  +       +A ++K     C+ C   K  + ++++  Q+I++  PF+++ +D  GPL +T   K+Y+  ++D+++K+    A    + +T+++ L++ +I +FG P+ +H D G++FEA  + E  +  GI+   ++ YH  +NG++ER  RT+ + + A L++   + W +++P   +  N +   TTG SP   +FGR+       +   ++ R D+ +R E +T+   +S
Sbjct:    4 ICGRGTELTIDTGAAVSLMSHELFNDIQPADLLPIQNVRLITAAGDELRVVGTSTVNISIGKSPPTSHTLLVAHSLTCPCLIGADFLRQHKCIIDFTSGTLQMNGYEVKLKTDRLSEHSIATASLATEDLRTYEEIIDSMCASGATENDYETREQLKKLFWKYKGVLPTTDDDLGRTSVVRHRIRTGNAKPIKMGPRRMPHRDRPIIQDLVDRMLQQGVIERASSPWSFPVVLA-KKKNGSFRFCVDYRKLNDRTEKDVQPLPRIDDALDILSGSRWFSTLDLASGYWQVEVEPEDRPKTAFSTPTGSYQFRVMPFGLCNAPATFQRLMEQVLEGLQWKTCLVYLDDIIIFGRTTTEQMERLEEVLNRLQAAGLKVKPSKCKLMTQEVVFLGHVVSGKGISTDPLKCATVENWEPPRCTNELRQFIGLASYYRKFVKNFASIAAPLHRLLQK-DKRWSWDDDCERAFQEMKRRLLTAPILKFPDFNKTFVLDVDASNDGLGAVLSQVHDDG-EHPIAYASRALTKPERRYCATRRELLALVWASKHFRPYLYGTRFKVRTDHNCLIWLNNFREP-EGQIARWLERLAEFDMEICHRPGKLHDNADALSRQTCGQCGKAVIPVAYAQAEPTQQQDQMNTA-------QNQDGDIKTLKEWIA-QDCWPSSCPEGVSRELRIFWGQRNALILDNGTLFRLWETPNSQRPLKLLVVPSHMRREILEELHDAPAGGHLGERRTLEKARCRFYWPGMAKDIKLWCRTCDACACRKGPSRRSRQPLQSIQTGYPFQRVGIDFLGPLPKTTTGKRYVLVVVDYFTKWTEAYATENMEAKTVAKVLVDNFITRFGPPESVHSDQGRSFEATLLAETFQLLGIKKTHTTSYHPQSNGLVERFNRTLLDTL-ALLSKRSPETWDEMLPWTTFAYNTSSHDTTGTSPFLALFGRE-------ARLPVDLRYDLPQREEPQTVTAYVS 959          

Query: 2026 TGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEP-IMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCG-TCVQCM-MEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENK-------DCKFIMENNTVLTKQGKIW---------------------------IPSDNRQRMIKEVHVLLC--HAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKI-----------DRMKWYSNKEINREDMEKRIEDKTLKPKISKTVRNFEMEDVVLIKQEIRNKDDA------------------------------RWEGPYKVIKKIHERSY-LLKDQNGKMVVRNVEKIKHFK 4587
            T  K LL+ FQ   N+F     D+G  N+ +H+I T   P I   PRR P+  +++ E  +K + +NGII + + PW +P+V V KK+    R C+D+R+LN+IT + ++P+P +D+ LD L+GS++FS++DL + Y+QV++  E +EKTAF+T +G + F  MPFG+  APGTF+ LM  VL+ L  +  +VYLDDI+I  +T ++H N   KV  ++  A L+L+P+KC+ FRKEV +LGHII+ DG++TD  K +A+  + +P+ V +LRSFLG+C YYRRF+++++  AR L  +  +      WTE CEK+F  +K+ALIT+PVL +P   KEFILDTDAS + IGAVLSQK     E VIAY S ++   E+ YC+TRKELLAI    +HF+HYLYG++F+LRTDH ++ +++  ++P   Q   WI  L   D ++++RKGTSH NAD LSR+ C  +C  C   E        I  ++LT       ++ Q   +E   IK  LE K         + I   +    +   +W                           +P    Q +++E H      H G  K     +     + L  +V+K    C  C   K   T+TK   Q      PFE++ +DI GPL  T    +Y+  ++D+++K+     I  Q+  T++E L+  WI ++G P  LH D G NF +    EL K  GI    ++  H  ++G++ER  RTI  +++  +++  + +W   +P       +   + TG +PA+++FGR +                  N+ +N  ++E R+E          +V  F  E + L  + ++ + D+                               WEGPY ++KK+++  Y + +  N K  V ++ ++  ++
Sbjct:  228 TAVKELLQEFQ---NLFSTSDSDVGRCNMTQHRINTGNHPPIKQYPRRLPLAKKEEAERLVKEMVDNGIIEESSGPWASPIVLV-KKKDGSTRFCVDYRKLNEITIKDSYPLPRIDDTLDALNGSQWFSTLDLKSGYWQVEIQPEDKEKTAFTTGQGLWQFKVMPFGLCNAPGTFERLMETVLRGLTSEACLVYLDDIIIVGRTFQEHINNIRKVFQRLQKANLKLSPKKCRFFRKEVSYLGHIISADGVKTDPEKTKAVVDWPRPETVHDLRSFLGLCTYYRRFVRNFSAIARPLHKLT-EARSNFNWTEECEKSFNNLKQALITSPVLTYPRTDKEFILDTDASNEGIGAVLSQKI-GNEECVIAYFSKSLGKPERNYCVTRKELLAIVKSIEHFHHYLYGRKFLLRTDHASLRWLLNFREP-EGQIARWIQRLQEYDFEIQHRKGTSHGNADALSRRPCKESCKHCTNAEKRFGMETDISMKVLTTEDAWSSSEVQKAQLEDPAIKPILERKLNSEDRPSWQEIAPESPATKRYWALWDSLHLKDGVLYRKWESDDGSSGRWQLILPKSRIQEVLRETHESASGGHFGVMKTLSKTRERFYWDRLRADVEKWCRECHACGARKGPKTRTKGRLQRYNVGAPFERMALDILGPLPVTAKGNRYVLVLMDYFTKWPEAIPIPDQEASTVAEELVRAWISRYGVPMILHSDQGTNFNSALFTELCKLLGILKTRTTALHPESDGMVERFNRTILNHLSLFVSK-NQTDWDTHLPLFLLAYRSADDEATGCTPADMLFGRTLRLPCDILFGRPSDTPSSPNEYLN--NLEARLE----------SVHAFARERIKLASERMKTRYDSGATGHHFKEGDQVWMYNPKRWRGLSPKLQQNWEGPYTIVKKLNDVIYRVQRSPNAKPKVIHINRLTPYR 1142          

Query: 2050 IFQANKNVFMADKWDIGCTNLIKHKI-ITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGK---NNEKIR----------WTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEK---GYCITRKELLAI-YYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTC----------GTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNK---------------------WQNDNME-VQEIKNKLEN-----KDCKFIMENNTVLTKQ----------GKIWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK----IDRM 4320
            + + ++N+F     D+GCT L++H I +    P+  + RR P +  D ++  I+ L  + ++R  +SP+ +P+V V KK+   IRLC+D+RQLN  T + AFP+P ++E LD L GS++FS++DL + Y QV + ++ +EKTAF T  G F FNRMPFG+  AP TFQ LM ++  D     +++YLDDI+IF+   + H      VL ++    L+L  EKC  F+  V +LGH+I++ G++TD  KI A+  +++P  VK +RSFLG  +YYRRF++ +A  A  L  + G    + ++ R          W E+CE +F  +K+ L+ APVL F DF + FI++ DAS   +GAVLSQ+ E G    IA+ S  +   E+    Y   + ELLA+ +   + F  YL G +F + TD+  ++++ + K  + A  Q W + L+  + +++YR GTS+ NAD LSR             G  V   +   D +T      +++ T +   ++                     W+       +E++N+ E      +  + I+E   VL +            ++ +P   +  ++  +H    H G ++ T  ++  C    +  ++KK    CERC   K +  K +    ++ +T P E + MD    L+   N ++ +  + D +SK+    A+  Q   T+   L+ KW   +G PK +H D G++FE   +K L +T GIE   ++PYH   NG  ER  RT+ + +     E  RK W  ++P + +  N T+ ++T  SP E++FG+K    IDRM
Sbjct:  324 LLRRHQNLFSEHAGDLGCTTLVQHSIPLLDSVPVRQRYRRLPPSQYDLVKAHIQELVEHQVVRPSSSPYASPIVVVQKKDG-SIRLCVDYRQLNAKTRKDAFPLPRIEESLDALSGSKWFSTLDLASGYNQVPVLEKDKEKTAFCTPFGLFEFNRMPFGLCNAPSTFQRLMERIFGDQSFHTLLLYLDDIVIFSSDLQQHLQRLDMVLSRLQQHNLKLKLEKCHFFQTRVSYLGHVISESGVETDPEKIRAVVDWKRPTTVKEVRSFLGFASYYRRFVEGFAALAAPLHKLVGALQGSKKQPRSKMHSIVIPHWDEVCETSFRALKDRLVRAPVLGFADFTRPFIVEIDASHTGLGAVLSQEQE-GKRRPIAFASRGLRPSERNMSNYSSMKLELLALKWAVTEKFREYLLGTQFTVYTDNNPLSYLQSAK--LAAVEQRWASQLALFNYELKYRPGTSNGNADALSRLPADTDQSSVGVRGISVPPEVPLADKETASRSQVVISSTVDAIPSRSSVDLQILQAADPLIAAFSVYWRRGQAPTARELRNEREGVKELVRQWQRIVERQGVLYRSVQLPPAKHTVFQLVLPKALQTEVLLALHDQHGHQGMERTTDLVRQRCYWPKMWQDIKKWCTECERCSIAKAMHPKVRTFMGSLLATRPLEILAMDFTV-LERASNGQENVLVLTDVFSKFTQAYAVADQKASTVVRVLVEKWFYVYGVPKRIHSDQGRSFEGELLKHLCETYGIEKSRTTPYHPEGNGQCERFNRTLHDLLRTLPPEKKRK-WPQLLPHLLFAYNTTIHQSTQYSPYELLFGQKPQLPIDRM 1143          

Query: 1624 LDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESLR-----CANNSRLETMGKLNINVKMGSMERNVTFIIVKN--LIPEIIGGVELQRLFGIELK-----YILEEH-------EKRSDFICEIEARFGRIITDEERLRHAIDVLKVTGNKRLLE----IFQANKNVF-MADKWDIGCTN------LIKHKIITKGE-PIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLS----RKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNK----LENKDCKFIMENNTVLTKQGKIWIPSDNRQRMIKEVH--VLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK----IDRM-------KWYSNKEINR-EDMEKRIEDKTLKPKISKT--------VRNFEMEDVVLIKQEIRNKDD--------ARWEGPYKVIKKIHERSYLLK--DQNGKMVVRNVEKIKHF 4584
            L ++G++V  ++DTG+  +++ +   DR++  +  E   S R      AN       G + ++ ++G  +    F +++N   +  ++ G++     G+ L      YIL          E  S      + R    I  E+ +   +D  +     +L+E      QA +++  +  +W   CTN      ++ H I T    PI  KP +  I  +  I+EAI++++  GI+R   SPW +P+V V KKE   +R C+D+R++N  T   A+PMP V EIL+ LHG+  FS++DL + Y+QV L+ +S  KTAF T +G + F  +PFGI  A  TFQ LM  VL +L      VY++DI++++ T E H     +V   +  AGL LN  KC + ++ + FLGH+I+ +GI T+  K+EAIQ+F +P+ +K L+ FLG+  +Y RFI  ++++A  L ++  KN   I WT+ C+KAF ++K+ALITAPVL  P+F + F + TDAS   +GAVLSQ  + G EHV+AY S  +   E+ Y    KE LA+ +  + +  YL G+ F + TDH A++++    KP T++   W   L + D  ++YRKG  +   D LS    R T G    C +             I       G  + Q D    QE +      +   D  F    N  L    ++ +P  +R+  ++  H   L  H G  K    + N     ++  +V    ++CE CQK K   +K     Q+    EP   + +D+ GPL ++  + +++  I+D+ SK++ +  + +     I + L+     ++G P  L  D G  F +R +    +  G+    ++ YH  TN + ER  RT++  I AS  +   + W   +PE  + +N+  Q++TG +PAE+  GRK    ++R+          + K + R +D+  +I D   K +  +           NF   D+V ++    ++ D         +W+GP K+I+KI   +Y ++  D + ++   +VE +K++
Sbjct:  430 LSVRGQQVTAMIDTGSTFSLIQEGTWDRMKRTQ--EVWRSGRGQKFILANGQTQTAKGVVELDCELGKCQAKRPFYVMENKDHVFSLVLGLDFLHDTGLILDFQKDVYILPGGDTVPFGGEGESPPFSYADMRL--CIAQEDYV--PLDYEEEQEINKLVEGADITSQAKQDLHKLLSQWPSVCTNQLGRTMIVLHHITTNDNLPIRQKPYKVSIEKQQLIKEAIEDMQRRGIVRPSTSPWASPVVLVPKKEG-GVRFCVDYRRMNSKTHLDAYPMPQVQEILESLHGAAIFSTLDLKSGYWQVGLEPDSIPKTAFITCQGLYEFTVLPFGIKNAAATFQRLMDSVLVNLKGKSCFVYINDIVVYSSTIEQHLGHLEEVFRCLHQAGLTLNLRKCNLLQRSLIFLGHVISGEGICTEPGKVEAIQAFPEPRSIKELQRFLGMAGWYHRFITHFSERAAILNALKKKNAPWI-WTQECQKAFEDIKQALITAPVLTPPNFSEPFQIQTDASDQGLGAVLSQGTD-GLEHVVAYASRLLQGAERNYSTAEKECLAVVWAVEKWRVYLEGRHFTVITDHSALSWVFNHPKP-TSRLTRWAIRLQTFDFSVQYRKGKCNIVPDTLSRIPDRMTEGVMAPCQVTGSSDGLPVDWAEIARAQEVDGTLQPQRDETGNQETRKDRIHFVTKNDILFRAVPNQQLGHTLQVVVPVQHREAFLQYAHDNPLSGHLGQMKTLLRLLNIAYWPSIRRDVWTYCKSCEICQKYKPRISKLSGRLQSTPVVEPGYMLGVDLMGPLPKSPRQNEHLLVIVDYCSKWVEMFPLREAKTSQIVQILIKDIFTRWGTPAYLVSDRGAQFTSRLLHATCRQWGVVQKLTTAYHPQTN-LTERVNRTLKTMI-ASYVKDKHRLWDQWIPEFRFAINSAWQESTGFTPAEVALGRKLKGPLERLLSQPPNPDHDAYKVVQRQQDLFCQIRDNVDKAQAKQAKFYNRRRKQVNFVGGDLVWVETHPLSRADKGFAAKLAEKWKGPAKIIRKISPVNYEIEYLDDSSRVDTIHVENLKYY 1475          

Query: 2047 EIFQANKNVFMADKWDIGCTNLIKHKI-ITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESIC-----GKNNEKIR-----WTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEK---GYCITRKELLAI-YYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDA-----KTGKIKTRILTVTAE------------------GGY------NKWQNDNMEVQEIKNKLE-----NK--DCKFIMENNTVLTKQG-----KIWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK 4308
            ++ Q   +VF  D+ ++GCT+LI+H+I +    P+  + RR P +  D ++  I+ L +  +IR   SP+++P+V V K++   IRLC+D+RQLN  T + A+P+P ++E LD L G+R+FS++DL + Y QV + +  + KTAF T  G F FNRMPFG+  AP TFQ LM ++  D     +++YLDDI+IF+ T + H      VL ++    L+L   KC  F+ +VK+LGH+I+  G+ TD  KI+A+  +++P+ V  LRSFLG  +YYRRF++ +AK A  L  +      GK   K +     W++ CE+AF  +K  L++APVL + DF K FIL+ DAS   +GAVLSQ D++G    IAY S  +   E+    Y   + ELL + +   + F  YL G +F + TD+  ++++ T K  + A  Q W++ L+  +  ++YR G S+ NAD LSR       Q   E         + G  K  I T+ A                   G +       K+       QE K  LE     NK  +C  ++   T  T  G     ++ +P   ++ ++  +H    H GA++    ++  C   ++  ++++  + C RC   K    K +     + +++P E I +D    +    + ++ +  I D +SK+        Q   T++  L+ KW   +G P+ +H D G+NFE+  +K L K   ++   ++PYH   NG  ER  RT+ + +    +E  R+ W   +P++ +  N TV +TT  SP E++FGR+
Sbjct:  291 DLLQRYSSVFSQDEGELGCTHLIEHEIPLIDDTPVKQRYRRLPPSQYDLVKGHIQELLDRKVIRASCSPYSSPVVVVQKRDGT-IRLCVDYRQLNSKTRKDAYPLPRIEESLDALGGARFFSTLDLASGYNQVPMAEHDKSKTAFCTPFGLFEFNRMPFGLCNAPSTFQRLMERIFGDERFQSLLLYLDDIVIFSSTFDLHLQRLEVVLKRLQQNNLKLKLSKCHFFQSQVKYLGHVISSAGVATDPEKIKAVSEWERPQTVTQLRSFLGFASYYRRFVEGFAKHASPLHRLVAVLQGGKRRVKTKPVEGHWSDACEEAFETLKLKLVSAPVLGYADFSKPFILEIDASHGGLGAVLSQ-DQEGGRRPIAYASRGLRDSERNMSNYSSMKLELLGLKWAVTEKFREYLLGAQFTVYTDNNPLSYLQTAK--LGAVEQRWVSQLALFNFNIKYRPGLSNRNADALSRLPACPTPQSFQETVSGISIPLQVGATKATISTIDAVPLRPKADLQRLQSADPVIGPFLQYWHRQKFPTAGERAQESKEVLELVRQWNKLRECDGVLYRLT-RTPDGVEEFLQLVLPECLQKEVLTALHDNHGHQGAERTASLVRQRCFWPHMWKKIERWCKECSRCVVAKMGQPKIRTFMGNLSASKPLEIIAIDFTL-MDRASDGRENVLVITDVFSKFTQAFPTQDQRASTVAHILVEKWFYVYGVPQRIHSDQGRNFESDLLKSLCKIYDVKKSRTTPYHPQGNGQCERFNRTMHDLLRTLPSEQKRR-WPKYLPQLLFAYNTTVHQTTAHSPYELMFGRQ 1093          

Query: 2005 AIDVLKVTGNKR--LLEIFQANKNVFMADKWDIGCTNLIKHKI-ITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALE----SICGKNNEK-------IRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEK---GYCITRKELLAI-YYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRK----------TCGTCVQCMMEHEDAKTGKIKT--RILTVTAEGGYNKWQNDNMEVQEI--------------KNKLENKDCKFIMENNTVLTKQGKIW----------------IPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK 4308
            A+D+  +T  ++  +  + Q   +VF A   D+GCTNLI+H+I +    P+  + RR P +  + ++  I  L    ++R+ +SP+ +P+V V KK+   +R+C+D+R LN  T + AFP+P ++E LD L G+R+FS++DL + Y QV + ++ + KTAF T  G F +NRMPFG+  AP TFQ LM ++  D     +++YLDDI++F+ +   H      VLG++   GL+    KC  F++EV +LGH+I+  G+ TD  KIEA+  +Q+P+ V  LRSFLG  +YYRRF++ +A+ A  L     ++ G   +K       + WT  CE++F  +K  L++APVL + DF   FIL+ DAS+  +GAVLSQ+ + G    +AY S  +   E+    Y   + E LA+ +   + F  YL G + V+ TD+  ++++ + K  + A    W   L++ D +++YR G S+ NAD LSR+            GT V  +++         +    +L  ++    +  Q+ +  ++E+              K ++       + + + ++ + G ++                +P+  +  ++K++H    H G ++ ++ ++  C    +  ++K+    CERCQ  K            + ++ P E + +D    L+ + N  + +  + D +SKY        Q   T+++ LL +W  KFG P  +H D G++FE+  I++     G+E   ++PYH   NG  ER  RT+   +  +L    +++WA  +P++ +  N T  + TG SP  ++FG++
Sbjct:  250 AVDLSALTDQEQGVVRSLLQKYNSVFSAHDGDLGCTNLIEHEIPLLDNIPVRQRHRRIPPSDYELVKAHIDQLLEAQVVRESSSPYASPIVLV-KKKDGSLRMCVDYRLLNSKTRKDAFPLPRIEESLDALSGARWFSTLDLASGYNQVPVAEQDKPKTAFCTPFGLFEWNRMPFGLCNAPSTFQRLMQRMFGDQQYQSLLLYLDDIIVFSSSVSQHLQRLEVVLGRLQKEGLKAKLSKCVFFKQEVGYLGHVISNKGVSTDPAKIEAVAQWQRPRTVSELRSFLGFASYYRRFVEGFAQLAGPLHKLVAALVGSKTKKGSGQALGMAWTAQCEQSFEALKARLVSAPVLAYADFSLPFILEIDASYSGLGAVLSQEHD-GAVRPVAYASRGLRPPERNMDNYSSMKLEFLALKWAMTEKFREYLLGHKCVVYTDNNPLSYLQSAK--LGAMEHRWAAQLAAFDFEIKYRSGRSNKNADALSRQYQLGPSVTEYVPGTPVPELVQQASPVVSATQALVSVLPGSSPVDIHSLQDADPLLREVLVFWRKQVQPTSAEKRQVSRPAMALLRQWDRLVERDGVLYRRVFRPDGGEESFQLLLPAVLKPEVLKQLHQDHGHQGIERTSELVRQRCYWPGMFADIKQWCRECERCQVAKDAGPVPHSFMGHLLASRPNEIVAIDFTV-LEPSRNGLENVLVMTDVFSKYTIAVPTRDQRASTVAQVLLREWFYKFGVPGRIHSDQGRSFESALIQQFCHLYGVERSRTTPYHPAGNGQCERFNRTLHNLLR-TLPTSRKQDWASNLPQVIFCYNTTPHQGTGESPYYLMFGQE 1071          

Query: 2062 NKNVFMADKWDIGCTNLIKHKI-ITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIR--------------WTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAI-YYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSR----------KTCGTCVQCMMEHEDAKTGKIKTRILTVT-AEGGYNKWQN------------DNMEVQEIK---------------------------------NKLENKDCKFIMENNTVLTK------QGKIW---IPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGR--------------KIDRMKWYSNKEINREDMEKRIEDKTLKPKISK-----------TVRNFEMEDVVLIK---QEIRNKDDARWEG-PYKVIKKIHE-RSYLLKDQNGKMVVRNVEKIKH 4581
            N +VF     D G T ++KH+I +    P  +  R+ P +    + +AI  +E  G+IR   SP+ +P+V V KK+   +R+C+D+R+LN  + R AFP+P V+E L+ L  ++YFS++DL + Y+QV++ +  + KTAFST  G F  NRMPFG+  +P TFQ LMT    DL  + +++YLDDI+IF++T ++H      V  ++   GL+L P+KC + R+EV +LGH+++ DGI+TD  KI  +  ++ P+    L  FLG   YYRRFI+ YA  A  L  +   +  K +              WTE CE AF  +K  L TAPVL + D+ + F+L TDAS   +GAVL+Q  + G E VIAY S  ++  E  Y   + E LA+ +     F  +LYG +F + TD+  + +++TT K + A  Q W+  LS  D  + YR+G  + NAD LSR           TC   V    + +  + G    R +  T +E G NK  +             +M  QEI+                                  KL  K+ K ++  + +L +      +G  +   +P   R  +   +H    H G ++    ++       +  +VK   E CERC   KT T   +    +I +  P E I +D    ++++    + I  + DH+S++        Q   T+++ L   +  KFG P +LH D G+NFE+  +KEL +  G +   +SPYH   NG  ER  RT+   +  +L    +  W + +  + +  N T   +TG +P  ++FGR                D  +     +   + ++   E   L  + SK            VR F   D VLIK    E R K   RWE  PY VIKK      Y+++ ++G      VE++ H
Sbjct:  210 NSDVFSKHHLDYGHTTVVKHEIPLVDPRPFRLPYRKIPPSQYQAVRKAITEMEEAGVIRPSKSPYASPIVVVTKKDG-SLRICMDYRKLNSCSTRDAFPLPRVEEALEALGEAKYFSTLDLTSGYWQVEVAEADKHKTAFSTPMGLFEANRMPFGLQNSPSTFQRLMTCCFGDLNFESLLIYLDDIVIFSRTFDEHLERLQMVFDRLRKYGLKLKPQKCHLLRREVLYLGHVVSSDGIKTDPDKISKVAGWKVPENRHELLQFLGFAGYYRRFIEGYASIAAPLYRLTSGDPRKKKRGRKGPPAVGLPFIWTEECENAFQTLKTKLTTAPVLGYADYSQPFVLQTDASLAGLGAVLAQVQD-GRERVIAYASRGLNPAETRYPAHKLEFLALKWAVTDKFYDHLYGHKFSVLTDNNPLKYVMTTAK-LDATGQRWVAQLSMFDFDIRYRQGGCNANADGLSRMPASEVAEALHTCPQLVPTSSQKQSQEKGDSAERAVDGTSSESGSNKEPSADQFLSAGSDALPSMSKQEIRAAQRTDPVIGPVLYYKCQYAKPKRSARTQSNEQEKLLRKEWKKLVVKDDILFRHVRDRQRGSFYQLVLPEKFRGYVKSSLHDESGHFGVERTFALVRERFYWPRMFNDVKTWCEQCERCCLRKTPTAGLRAPLVSIHTNAPLELICIDFLT-VEKSKGGFENILVVTDHFSRWAQAYPTKDQKAETVAKVLWKNFFCKFGFPAKLHADQGRNFESTVVKELCRLTGTQKSHTSPYHPQGNGTTERFNRTLMNLM-GTLPPQSKARWHEYIDALTHAYNCTRHDSTGYTPYYLMFGRHPRLPIDLVFGLAPATDYCEHSDYAKTLHDSLKYACEQANLTSRHSKDTQKKHYDVKAKVRQFTPGDRVLIKVCHTETRQKLGDRWEPKPYLVIKKQPGIPVYVVRSEDG-----TVERVIH 1150          

Query: 3628 DNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAK----TAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK 4308
            ++++ +++ VH    H G  +  K ++ +   + +  +++  I  CE C++     +          S  P+E + MD+ GP   T    +++  I+D+++K+  LT +  Q    +   L      +FG PK+L  +  + + A+  +E+ +     +G+ +      H   NG      + +R+ ++ +   G  ++W   + +  +  + +    T  SP  ++ GR+
Sbjct:   68 EDKRSILQRVHGA-DHCGQTRTRKLLEEHYYWKGMVNDIRDYINACEICKQKSYKRSSISHVKLLKASY-PWEVLGMDLLGPFPATSRAHRFVLLIVDYFTKWAELTPMTDQSAAHVVAALTTA-FHRFGFPKKLFCNVSEEYVAQINEEMFRHFPMCSGLAIS-----HLWANGAHRGTSQALRDCVSKA--TGRHRDWELQLEQRLFEYHTSKHSATRYSPFYLMLGRE 288          

Query:  710 GGRTYRDVV----QVGATKREINEWKPETRVKVIECWTCQKPGHSSRECNIKRR-----FQCYACGVEGHIRRECPTI-------KCHRCNARGHKEREC 961
            GG+++ D      + G   RE    +         C+ C K GH +REC   R+       CY CG +GH+ REC +        KC+ C  RGH +R+C
Sbjct:    2 GGKSFTDGCYRCGEGGHIARECPLPQDSVSSNTAACYNCGKGGHIARECPEGRQDRGGGPSCYTCGKQGHLARECSSGGGGPGDNKCYGCGQRGHMQRDC 101          

Query: 3628 DNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYI-SLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFS--SPYHHNTNGIIERQFRTIREYINASLNEGGR-----------KNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK 4308
            D ++ ++  VH    H G +K    ++ +     + ++VK +I +C  C+   +             S  P+E + +D+ GPL  T    +Y+  +ID++SK+  ++  I K  E   S   L     ++G P+++    GK F    + ++ K++ +   +   SP     +  +     ++R  +N + N+  +            +W   V +  +        TT  SP  ++FGR+
Sbjct:   76 DEKRNILMSVHGA-GHFGQKKTILKLEADYYWLGMISDVKNLIASCGVCRNKGSRRVAMPSMKLLKASG-PWEVLGLDVLGPLPVTSRANRYLLLLIDYFSKWAEAVPLIEKSQEHVASA--LTVVFCRYGFPRKVFSSLGKEF----VTQVNKSSTLSRAYQRCSPSQTQVHAHV-----SVRVALNKATNQALKGCVNLVASQHPSDWESRVEQSLFEYRVGKHSTTQYSPFYLMFGRE 303          

Query: 3628 DNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYI-SLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFE-------------ARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK 4308
            D ++ ++  VH    H G +K    ++ +     + ++VK +I +C  C+   +             S  P+E + +D+ GPL  T    +Y+  +ID++SK+  ++  I K  E   S   L     ++G P+++    GK F              + +++ L +T G      + +H  TN       + ++  +N   ++    +W   V +  +        TT  SP  ++FGR+
Sbjct:   76 DEKRNILMSVHGA-GHFGQKKTILKLEADYYWLGMISDVKNLIASCGVCRNKGSRRVAMPSMKLLKASG-PWEVLGLDVLGPLPVTSRANRYLLLLIDYFSKWAEAVPLIEKSQEHVASA--LTVVFCRYGFPRKVFSSLGKEFVTQVNKIQHKKWCISHTLQNLCETRG-----PAGWHKATN-------QALKGCVNLVASQHP-SDWESRVEQSLFEYRVGKHSTTQYSPFYLMFGRE 299          

Query:  803 CWTCQKPGHSSRECNIKRRF---QCYACGVEGHIRRECPTIKCHRCNARGHKEREC 961
            C+ C KPGH   +C + R     QCY CG  GH+R EC   +C  CN  GH  REC
Sbjct:   25 CYNCNKPGHVQTDCTMPRTVEFKQCYNCGETGHVRSECTVQRCFNCNQTGHISREC 80          

Query:  737 QVGATKREINEWKPETRVKVIECWTCQKPGHSSREC---NIKRRFQCYACGVEGHIRRECPTIK-CHRCNARGHKEREC 961
            Q G   RE  E K  +R   + C+ C  P H +++C   +     +CY CG  GH+ R+C   + C+ CN  GH  ++C
Sbjct:   72 QTGHISRECPEPKKTSRFSKVSCYKCGGPNHMAKDCMKEDGISGLKCYTCGQAGHMSRDCQNDRLCYNCNETGHISKDC 150          

Query: 2608 DDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNY 2865
            DD++ F  + E+H     ++L  +  +G + + +K Q   + VKFLGH+I+++G++    K++ I+ ++ P   + LR F+G+C +
Sbjct:    1 DDVICFHSSFEEHLRGIERMLQAVRASGFK-SIKKSQFATRSVKFLGHVIDQNGVRPQPEKLD-IRQWETPTNEEELRKFIGVCTF 84          

Query: 2437 QVKLDKESQEKTAFSTK-EGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYL-DDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLG 2853
            ++ L ++S +    +T   G   + R   G+  +    +ELM +VL DL  +GV+V L DD+     T  + ++ + + L  +    LRL+  K  I  K    LG I +   ++    ++  +     P  V  +RSF+G
Sbjct:  186 KIPLSRDSLKYCGVATPFRGVRVYTRCAMGMPGSETALEELMCRVLGDLLAEGVVVKLADDLYCGGNTPHELFSNWKRTLQALHECNLRLSASKTIINPKTTTILGWIWSAGTLKASPHRVATLAQCPTPTTVGLMRSFIG 326          

Query:  770 WKPETRVKVIECWTCQKPGHSSREC-NIKRRFQCYACGVEGHIRRECPTIKCHRCNARGHKEREC 961
            +K E R   I C  C + GH + +C + K+  +C  CG +GH +R CP   C  C+  GH+ R C
Sbjct:    4 YKEEKRSMYIRCHNCNERGHMAVDCPDPKKVIKCCLCGGQGHYKRSCPNELCFNCDQPGHQSRVC 68          

Query: 2419 LGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEED 2643
            + + Y+  KL   +     F+T  G+F F RMPFGI+ A    Q+++ +   D+  +GV+   DDI++  KTE +
Sbjct:    1 MSSCYWHKKLTDAASLLCTFNTPFGRFRFRRMPFGISCASEVAQKMVEEHFGDI--EGVLPVYDDIIVSGKTEAE 73          

Query: 1972 RIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIIT-KGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTC--GTCVQC---------MMEHEDAKTGKIKTRILTVTAEGGYNKW---QNDNMEVQEIKNKLE-------------NKDCKFIMEN-NTVLTKQG---KIW-------------IPSDNRQRMIKEVHVLL--CHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGV------------SPAEIIFGRKIDRMKWYSNKEINREDMEK----------RIEDKTLKPKISKTVR----NFEMEDVVLIKQEIRNKD-----DARWEGPYKVIKKIHERSYLLK-DQNGKMVVRNVEKIKHFK 4587
            R+   +E  R + D L+      L ++    +++F   + ++G T+L+ H+I T    PI  +PRR P+  +   + AI+ +   GII   +SPW + +V V KK+   +R C+D+R LN +T++ ++P+P +DE LD++ GS +FSS+DL + Y+QV L   ++ KTAF T  G + F  + FG+  AP TF+ LM KVL  + +   +VYLDDIL+   + +       KVL +IA AGL+L+P+KC   R+E++FLGH I  +GI T   K++A++ +  P  +++L+SFLG+ +YYRRF++ ++  A  L  +  K+ + + WT+ CE+AF  +K+AL  +P+L  PD +  FILDTDAS   +GAVLSQ    G E V+AY S  +S  E+ YC+TR+ELLA+     HF +YL G  F +RTDH A+ +++T K+P   Q   W+  L+S    +E+R G+ H NAD +SR+ C    C  C         +   E + TG+    +  +       +W   Q  ++++Q +   +E             +   K + E  + +  K G   + W             +P   R  +++  H      H G  K  + I+       L  +V+     C+ C   K    +++ E Q + +  P E++ +DI GP   T    +++   +D+++K+    AI  Q+  T+++ L+     +FGA + +H D G+NFE+     + +  G+    ++P H  ++G++ER  RT+ + + A L    + +W + +P +     + VQ +T              +PAE+ FG+  D +      E  R+  ++          ++E   ++ K +  +R    +F+  D+V +    R K      D +W GP +V++K+ E  Y ++    G+ V  + +++  ++
Sbjct:  214 RVTAVKEIWRRSCDGLQPGQKDELWKVLLEYRDIFALSEDEVGLTHLVHHEIDTGDARPIKTRPRRLPLAHQVAADSAIEEMLRGGIIEPSDSPWASGVVMVKKKKGPKMRFCVDYRPLNGVTKKDSYPLPRIDESLDLVSGSSWFSSLDLRSGYWQVPLSPAARPKTAFCTGRGLWQFRVLSFGLCNAPATFERLMEKVLASIPRQECLVYLDDILVHGGSFKAALESLRKVLQRIAAAGLKLHPDKCCFMRRELEFLGHKIGGEGISTLEEKVQAVRDWPTPTTLRDLKSFLGLASYYRRFVRGFSCIAAPLFHLQRKDCDFV-WTQECEQAFSSLKKALTNSPILTPPDPKLPFILDTDASDVGMGAVLSQMGSAG-ERVVAYFSKTLSKAERRYCVTRRELLAVVKAIGHFRYYLCGLPFTVRTDHSALQWLMTFKEP-EGQIARWLEELASFSFTVEHRPGSRHANADAMSRRPCALAGCQYCEKREAREAVISREEQSHTGESSWPVCRLVQGVDSTEWRAHQEQDVDLQPVLQWVEAGRKPEWGEVAGCSPGSKGLFEKFDALRLKDGVLQRAWKEPATGEERWQVVVPRTLRNSVLQGCHGAAGSGHFGVSKTLRRIRQGFYWGQLRRDVEDFCRRCDICTAHKGPPDRSRAELQQLAAGAPMERVAVDIMGPFPRTNRGNRFVLVAMDYFTKWPEAYAIPDQEAVTVADALVEGMFSRFGAAEVIHSDQGRNFESAVFSAMCERLGMRKTRTTPLHPQSDGLVERFNRTLVKQL-AILTSAHQSDWDEHLPLVLMAYRSAVQDSTLCTPALLMLGRELRTPAEMSFGKPPDALGAPPGPEYARKLQDRMDTAHAFARNQLEKAGIRQKRNYDLRAKGKDFKAGDLVWVYNPKRKKGRCPKLDCQWVGPCEVLEKLGEVVYRVELPPGGRRVTLHRDRLAPYR 1160          

Query: 2068 NVFMADKWDIGCTNLIKHKI-ITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGK-NNEKIR----------WTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEK---GYCITRKELLAI-YYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRK-----------TCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNK-------------------WQNDNMEVQEIKNKLENKDCKFIMENNTVLTKQG----------------KIWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK 4308
             VF   + D+GCT+LI H+I +    P+  + RR P +     +E I NL  + +IR+ +SP+ +P+V + KK+   +RLC+D+RQLN  T + AFP+P ++E LD L G+R+FS++DL + Y+QV + +  + KTAF T  G F +NRMPFG+  AP TFQ LM ++  +     +++YLDDI++F+ T E H      VL ++   GL++   KC  F+ +V +LGH+I+  G+ TD  K+EA+ +++ P  V  LRSF+G  +YYRRF++ +AK A  L  +  +    K+R          WTE C+++F  +K  L T PVL + DF + FIL+ DAS   +GAVLSQ+ E G    IAY S  +   E+    Y   R E LA+ +   + F  YL G++ ++ TD+  ++++ T K  + A  Q W   L++ D+++ YR G S+ NAD LSR+             G+C+  M   +  +T  + T   T+ A   ++                    W+       E + +L +     + + N ++ + G                +I +P   R+ ++  VH    H G  +    ++  C    ++ EV +    CERCQ  K      +     + +++P E + MD    L+ T +  + +  I D +SKY    A   Q   T+++ L+ +W  KFG P  +H D G++FE+  I++L     +E   ++PYH   NG  ER  RT+ + +  +L    +++W   +P++ Y+ N T   +TG SP  ++FG++
Sbjct:  321 TVFSLHEGDLGCTSLITHEIPLVDDAPVRQRYRRIPPSDYVAAKEHINNLLQSQVIRESSSPFASPIVLIRKKDG-GLRLCVDYRQLNSRTRKDAFPLPRIEESLDALSGARWFSTLDLASGYHQVAVAEADRPKTAFCTPFGLFEWNRMPFGLCNAPSTFQRLMQRMFGEQQGQSLLLYLDDIIVFSSTIEQHLERLELVLERLQLEGLKVKLAKCAFFQHQVHYLGHVISDQGVSTDPGKVEAVANWEPPTTVFQLRSFIGFASYYRRFVEGFAKLAAPLHRLVAELEGNKVRKKSARGLTNHWTEECQRSFEALKAKLTTTPVLAYADFSRPFILEVDASNGGLGAVLSQEQE-GKVRPIAYASRGLRPTERNPVNYSSMRLEFLALKWAVAEKFREYLLGQKCIVYTDNNPLSYLSTAK--LGAMEQRWAAQLAAFDLEIRYRSGRSNRNADALSRQHFPDMQAWRDVLPGSCLP-MSLQQVQQTETVGTTQATMVALPHHSPSDMASLQGADPVLKEFLPFWERQTRPSPEERRQLSSPTLALLRQWNRLVEQGGVLYRRVFRDDGGEAVLQILLPGSIREEVLTAVHQQHGHQGVDRTLDLLRQRCYWPGMSAEVAEWCSQCERCQVAKVTRPAARAPMGHLLASKPNEILAMDFSV-LEPTTSGIENVLVITDIFSKYTMAVATRDQRAATVAQVLVTEWFSKFGVPARIHSDQGRSFESALIQQLCDLYAVEKSRTTPYHPEGNGQCERFNRTLHDLLR-TLPVSRKRDWNVCLPQLLYSYNTTPHHSTGESPFFLMFGQE 1122          

Query: 2068 NVFMADKWDIGCTNLIKHKI-ITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGK-NNEKIR----------WTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEK---GYCITRKELLAI-YYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRK-----------TCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNK-------------------WQNDNMEVQEIKNKLENKDCKFIMENNTVLTKQG----------------KIWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK 4308
             VF   + D+GCT+LI H+I +    P+  + RR P +     +E I NL  + +IR+ +SP+ +P+V + KK+   +RLC+D+RQLN  T + AFP+P ++E LD L G+R+FS++DL + Y+QV + +  + KTAF T  G F +NRMPFG+  AP TFQ LM ++  +     +++YLDDI++F+ T E H      VL ++   GL++   KC  F+ +V +LGH+I+  G+ TD  K+EA+ +++ P  V  LRSF+G  +YYRRF++ +AK A  L  +  +    K+R          WTE C+++F  +K  L T PVL + DF + FIL+ DAS   +GAVLSQ+ E G    IAY S  +   E+    Y   R E LA+ +   + F  YL G++ ++ TD+  ++++ T K  + A  Q W   L++ D+++ YR G S+ NAD LSR+             G+C+  M   +  +T  + T   T+ A   ++                    W+       E + +L +     + + N ++ + G                +I +P   R+ ++  VH    H G  +    ++  C    ++ EV +    CERCQ  K      +     + +++P E + MD    L+ T +  + +  I D +SKY    A   Q   T+++ L+ +W  KFG P  +H D G++FE+  I++L     +E   ++PYH   NG  ER  RT+ + +  +L    +++W   +P++ Y+ N T   +TG SP  ++FG++
Sbjct:  321 TVFSLHEGDLGCTSLITHEIPLVDDAPVRQRYRRIPPSDYVAAKEHINNLLQSQVIRESSSPFASPIVLIRKKDG-GLRLCVDYRQLNSRTRKDAFPLPRIEESLDALSGARWFSTLDLASGYHQVAVAEADRPKTAFCTPFGLFEWNRMPFGLCNAPSTFQRLMQRMFGEQQGQSLLLYLDDIIVFSSTIEQHLERLELVLERLQLEGLKVKLAKCAFFQHQVHYLGHVISDQGVSTDPGKVEAVANWEPPTTVFQLRSFIGFASYYRRFVEGFAKLAAPLHRLVAELEGNKVRKKSARGLTNHWTEECQRSFEALKAKLTTTPVLAYADFSRPFILEVDASNGGLGAVLSQEQE-GKVRPIAYASRGLRPTERNPVNYSSMRLEFLALKWAVAEKFREYLLGQKCIVYTDNNPLSYLSTAK--LGAMEQRWAAQLAAFDLEIRYRSGRSNRNADALSRQHFPDMQAWRDVLPGSCLP-MSLQQVQQTETVGTTQATMVALPHHSPSDMASLQGADPVLKEFLPFWERQTRPSPEERRQLSSPTLALLRQWNRLVEQGGVLYRRVFRDDGGEAVLQILLPGSIREEVLTAVHQQHGHQGVDRTLDLLRQRCYWPGMSAEVAEWCSQCERCQVAKVTRPAARAPMGHLLASKPNEILAMDFSV-LEPTTSGIENVLVITDIFSKYTMAVATRDQRAATVAQVLVTEWFSKFGVPARIHSDQGRSFESALIQQLCDLYAVEKSRTTPYHPEGNGQCERFNRTLHDLLR-TLPVSRKRDWNVCLPQLLYSYNTTPHHSTGESPFFLMFGQE 1122          

Query: 2035 KRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKP-RRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESIC---------GKNNEKIR---WTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEK---GYCITRKELLAI-YYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAE----------------------GGYNK-WQNDNMEVQEIKNKLEN------KDCKFIMENNTVLTK----------QGKIWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK----IDRM------------KWY----SNKEINREDMEKRIED----KTLKPKISKTVRNFEMEDVVLIKQE---IRNKDDARWEG-PYKVI 4500
            +R+  +      VF  D  D+GCTNL+ H+I    E  + +P RR P +  +     I+ L  + +IR+ +SP+ +P+V V KK+   +R+C+D+RQLN  T + AFP P +DE LD L G+++F+++DL + Y QV++ ++ + KTAF T  G F FNRMPFG+  AP TFQ LM ++  D     V++YLDD++IF+ + E H     +V  ++   GL++   KC  F+K+VK+LGH+++ +G+ TD  K   ++ +++P  + +LRSFLG  +YYRRFI  +AK A  L S+          GK  +K     W   CE++F E+K ALITAPVL + DF+K F+L+ DAS   +GAVLSQ+ E G    +A+ S ++   E+    Y   + EL+A+ +   + F  YL G    + TD+  ++ + T K  + A  Q W + L++ D+ ++YR G+ + NAD LSR+        ++E   A+  + + R+L V AE                      G + K W+   M     ++ L        +  K + E+ +VL +            ++ +P   ++ ++  +H    H G ++  + I++     N+ ++V+K    CERC   K +  K K    ++K++ P E + +D    L    + ++ +  + D +SKY        Q   T++E L+  W   FG P  +H D G+NFE+  +  L K   I+   ++PYH   NG  ER  RT+ + +  +L    ++ W   + ++ +  N TV ++TG++P  ++FGR+    +D +            +W     S+  +  E +++R+E+    + LK +      +FE  D V  +      RNK    W+  PY+++
Sbjct:  303 ERVKALLSKYNRVFAKDDLDVGCTNLMTHEIPLLDETPVRQPYRRIPPSQYELARSHIQQLLQSQVIRESSSPYASPIVLVQKKDG-GLRMCVDYRQLNARTRKDAFPSPRIDESLDALAGAQWFTTLDLASGYSQVEVAEKDKAKTAFCTPFGLFEFNRMPFGLCNAPSTFQRLMERLFGDCRFQSVLLYLDDVIIFSSSVEQHLQRLEQVFSRLDAQGLKVKLSKCHFFQKQVKYLGHVVSAEGVSTDPEKAAVVRDWRRPANLADLRSFLGFASYYRRFIAGFAKIASPLNSLVARLLPPGRKGKTPKKPVDEFWDAECEESFQELKTALITAPVLAYADFQKPFVLEVDASHGGLGAVLSQEHE-GKRRPVAFASRSLKPTERNMNNYSSMKLELVALKWAVTEKFREYLLGNACTVFTDNNPLSHLATAK--LGATEQRWASELAAFDLTIKYRPGSQNANADALSRQ------HPVLELSGARPLETE-RVLGVQAEMSTLPGLSPSDLYTLQRQDPVLGPFIKYWERGKMPDARERHGLSKPVRELIRQWKRLREHESVLYRCIYGSDGHGETNQLVLPQSLQESILHSLHDDHGHQGTERTLQLIRSRYYWPNMYSDVEKWCRTCERCVLSKALQPKVKTYMGSVKASRPHEILAIDFTV-LDPATDGRENVLVMTDVFSKYTQTVPTKDQRASTVAEALVKHWFQLFGPPARIHSDQGRNFESNLVHRLCKFYQIDKSRTTPYHPQGNGQCERFNRTLHDLLR-TLPPEQKRRWPRHLSQVTFAYNTTVHQSTGMTPYFLMFGREPRLPVDFLLGSDTEHDVPLDEWLEEHQSSLAVAYEAVQRRMENVRAQRDLKMQDQCLAPDFEEGDFVYTRNHGARGRNKIQDFWDPTPYQIV 1195          

Query: 2035 KRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKP-RRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESIC---------GKNNEKIR---WTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEK---GYCITRKELLAI-YYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAE----------------------GGYNK-WQNDNMEVQEIKNKLEN------KDCKFIMENNTVLTK----------QGKIWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRK----IDRM------------KWY----SNKEINREDMEKRIED----KTLKPKISKTVRNFEMEDVVLIKQE---IRNKDDARWEG-PYKVI 4500
            +R+  +      VF  D  D+GCTNL+ H+I    E  + +P RR P +  +     I+ L  + +IR+ +SP+ +P+V V KK+   +R+C+D+RQLN  T + AFP+P +DE LD L G+++F+++DL + Y QV++ ++ + KTAF T  G F FNRMPFG+  AP TFQ LM ++  D     V++YLDD++IF+ + E H     +V  ++   GL++   KC  F+K+VK+LGH+++ +G+ TD  K   ++ +++P  + +LRSFLG  +YYRRFI  +AK A  L S+          GK  +K     W   CEK+F E+K ALITAPVL + +F+K F+L+ DAS   +GAVLSQ+ E G    +A+ S ++   E+    Y   + EL+A+ +   + F  YL G    + TD+  ++ + T K  + A  Q W + L++ D+ ++YR G+ + NAD LSR+        ++E   A+  + + R+L V AE                      G + K W+   M     ++ L        +  K + E+ +VL +            ++ +P   ++ ++  +H    H G ++  + I++     N+ ++V+K    CERC   K +  K K    ++K++ P E + +D    L    + ++ +  + D +SKY        Q   T++E L+  W   FG P  +H D G NFE+  + +L K   I+   ++PYH   NG  ER   T+ + +  +L    ++ W   + ++ +  N TV ++TG++P  ++FGR+    +D +            +W     S+  +  E +++R+E+    + LK +      +FE  D V  +      RNK    W+  PY+++
Sbjct:  303 ERVKALLSKYNRVFAKDDLDVGCTNLMTHEIPLLDETPVRQPYRRIPPSQYELAHSHIQQLLQSQVIRESSSPYASPIVLVQKKDG-GLRMCVDYRQLNARTRKDAFPLPRIDESLDALAGAQWFTTLDLASGYSQVEVAEKDKAKTAFCTPFGLFEFNRMPFGLCNAPSTFQRLMERLFGDCRFQSVLLYLDDVIIFSSSVEQHLQRLEQVFSRLEAQGLKVKLSKCHFFQKQVKYLGHVVSAEGVSTDPEKAAVVRDWRRPANLADLRSFLGFASYYRRFIAGFAKIASPLNSLVARLLPPGRKGKTPKKPVDEFWDAECEKSFQELKTALITAPVLAYANFQKPFVLEVDASHGGLGAVLSQEHE-GRRRPVAFASRSLKPTERNMNNYSSMKLELVALKWAVTEKFREYLLGNACTVFTDNNPLSHLATAK--LGATEQRWASELAAFDLTIKYRPGSQNANADALSRQ------HPVLELSGARPLETE-RVLGVQAEMSTLPGLSPSDLYTLQQQDPVLGPFIKYWERGKMPDARERHGLSKPVRELIRQWKRLREHESVLYRYIYGSDGHGETNQLVLPQSLQESILHSLHDDHGHQGTERTLQLIRSRYYWPNMYSDVEKWCRTCERCVLSKALQPKVKTYMGSVKASRPHEILAIDFTV-LDPATDGRENVLVMTDVFSKYTQTVPTKDQRASTVAEALVKHWFQLFGPPARIHSDQGWNFESNLVHQLCKFYQIDKSRTTPYHPQGNGQCERFNLTLHDLLR-TLPPEQKRRWPRHLSQVTFAYNTTVHQSTGMTPYFLMFGREPRLPVDFLLGSDTEHDVPLDEWLEEHQSSLAVAYEAVQRRMENVRAQRDLKMQDQCLAPDFEEGDFVYTRNHGARGRNKIQDFWDPTPYQIV 1195          

Query: 1309 MDDDCMIDKDCSVFERDINNNSSVEIKKSNDKESQKKFKEECKVNEVVKHEERTIEKIYKFLKKNGDVCINEIVEDTREQNILSVEEQKSPVITYNIMQGRPSTTLDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESLRCANNSRLETMGKLNINVKMGSMERNVTFIIVKNLIPEIIGGVELQRLFGIELKYILEEHEKRSDFICEIEARFGRIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNTVLTKQGKIWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKIDRMKWYSNKEINREDMEKRIEDKTLKPKISKTVRNFEMEDVVLIKQEIRNKDDARWEGPYKVIKKIHERSYLLKDQNGKMVVRNVEKIKHFKKGG 4596
            MDDDCMIDKDCSVFERDINNNSSVEIKKSNDKESQKKFKEECKVNEVVKHEERTIEKIYKFLKKNGDVCINEIVEDTREQNILSVEEQKSP ITYNIMQGRPSTTLDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESLRCANNSRLETMGKLNINVKMGSMERNVTFIIVKNLIPEIIGGVELQRLFGIELK ILEEHEKRSDFICEIEARFGRIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNTVLTKQGKIWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCQKMKTITTKTKEETQTIKSTEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEI+YTLNATVQKTTGVSPAEIIFGRKIDRMKWYSNKEINREDMEKRIEDKTLKPKISKTVRNFEMEDVVLIKQEIRNKDDARWEGPYKVIKKIHERSYLLKDQNGKMVVRNVEKIKHFKKGG
Sbjct: 2449 MDDDCMIDKDCSVFERDINNNSSVEIKKSNDKESQKKFKEECKVNEVVKHEERTIEKIYKFLKKNGDVCINEIVEDTREQNILSVEEQKSPAITYNIMQGRPSTTLDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESLRCANNSRLETMGKLNINVKMGSMERNVTFIIVKNLIPEIIGGVELQRLFGIELKCILEEHEKRSDFICEIEARFGRIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNTVLTKQGKIWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCQKMKTITTKTKEETQTIKSTEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIKYTLNATVQKTTGVSPAEIIFGRKIDRMKWYSNKEINREDMEKRIEDKTLKPKISKTVRNFEMEDVVLIKQEIRNKDDARWEGPYKVIKKIHERSYLLKDQNGKMVVRNVEKIKHFKKGG 3544          

Query:  161 ASNMATIPTDLLIGRLLPEKFHRGDDLELFIKECQRFFEITKTPVKTQMVLVITLLDRTLIEEYEAAEGKTVEQKLRAAFHRPTSLIDDLREALNYEQGNDSAEIFIEKISKMTKKLASHTWNEEEIQKCLLTHCVRDKEVRKEIEMKDLXXXXXXXXXXXXXXXXXXXXXXVNTVRSIRPTTGGRTYRDVVQVGATKREINEWKPETRVKVIECWTCQKPGHSSRECNIKRRFQCYACGVEGHIRRECPTIKCHRCNARGHKERECYTNMERRNQGRDRDQRKMSGGRIQRNTYQQREDMYQPRNVHQRQWGNQQYNRKDIAAIESDDEMMNTKQSSQP 1180
            ASNMATIPTDLLIGRLLPEKFHRGDDLELFIKECQRFFEITKTPVKTQMVLVITLLDRTLIEEYEAAEGKTVEQKLRAAFHRPTSLIDDLREALNYEQ                                         EVRKEIEMKDLKTAEQIKETIKKIEKVNKVIEQVNTVRSIRPTTGGRTYRDVVQVGATKREINEWKPETRVK+IECWTCQKPGHSSRECNIKRRFQCYACGVEGHIRRECPTIKCHRCNARGHKERECYTNMERRNQGRDRDQRKMSGGRIQRNTYQQREDMYQPRNVHQRQWGNQQYNRKDIAAIESDDEMMNTKQSSQP
Sbjct: 2148 ASNMATIPTDLLIGRLLPEKFHRGDDLELFIKECQRFFEITKTPVKTQMVLVITLLDRTLIEEYEAAEGKTVEQKLRAAFHRPTSLIDDLREALNYEQ-----------------------------------------EVRKEIEMKDLKTAEQIKETIKKIEKVNKVIEQVNTVRSIRPTTGGRTYRDVVQVGATKREINEWKPETRVKMIECWTCQKPGHSSRECNIKRRFQCYACGVEGHIRRECPTIKCHRCNARGHKERECYTNMERRNQGRDRDQRKMSGGRIQRNTYQQREDMYQPRNVHQRQWGNQQYNRKDIAAIESDDEMMNTKQSSQP 2446          

Query: 1609 RPSTTLDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESL-RCANNSRLETMGKLNINVKMGSMERNVTFIIVKNLIPEIIGGVELQRLFGIELKYILEEHEKRSDFICEIEARFGRIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYN------KWQNDNMEVQEIKNKLENKDCKF-----------------IMENNTVLTKQGK--IWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCXXXXXXXXXXXXXXXXXXXXEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNG 4140
            R  + ++I G  V+ L ++GA I+VM++     + +  ++++R  L    +N   + +G + I  K     R +  IIV+ + P  IGGV+  ++FG+ELK   E +   S  +     RF    TD +RL++ +  LK+  N  L  +     N+FMA ++D+G T +I H++ T G PI+  PR QP++LE K+EE ++NL   G++RKC SPWNTPLV V K +   +R+CLDFR LN +TE+ +FPMP++  +LD L  S+ F SIDLG AYY V+L++ SQ KTAFSTKEGQFCFNR+PFG++ AP TFQ+LM ++L+ L   GV+VYLDDILI+ + +E H  +  +V  +I  +GL++NPEKC   +  + F+GH +++ GIQT+  KI  I++  +PK    LRSFLG+  YYRRFIK+Y+  A  L +     ++ I WTE C K F  +K+ L  AP+L +P   + FI+DTD SF+ IG                     ++ HE GYC+TRKELL ++ F  HF  YLYG+RFV RTDHKA+TFM TTKKPI+ QFQTW+   S  D  ++YRKG  H NA   SR     C    MEH+DAK  K +TR +  + +G  N      + QN++    +I + L   +                    I +N  ++   GK  + +P    + ++   H+ LCH G  K   Y+++   + ++   + + I  C+ C   K    +TKE           E+I +DI     ET   KKY+  IID +SK +SL     QDE TI   +LN WI +FG P+ +  D  + FE    ++  +  GI+  FSSPY H +NG
Sbjct:  283 RKWSIMEINGFHVEMLWNSGASISVMSEKCWRLIGSPILMDSRILLSEVFSNEDKKPLGSVKIVAKWNKKFRELNVIIVRKIHPNFIGGVDTMKIFGMELK---EVNNIESSLV---NKRF----TDSDRLKNTLLTLKLDKNSELGTLISQFSNIFMASRFDLGHTKVITHELKTSGPPILQNPRGQPMHLEAKVEELVQNLLEAGVVRKCQSPWNTPLVIVGKPDG-SVRICLDFRLLNSVTEKFSFPMPDMQLLLDCLGKSKIFYSIDLGQAYYLVELNENSQIKTAFSTKEGQFCFNRLPFGLSTAPATFQKLMHQILEGLVFKGVVVYLDDILIYGENQETHDKLLFEVFTRIRDSGLKVNPEKCAFNKSVLNFIGHTVSEKGIQTNKRKISEIENATEPKSTTELRSFLGLTTYYRRFIKNYSMIAAPLYAATTGCDKMIVWTEECRKRFINLKKLLCEAPILEYPRADRLFIIDTDDSFEAIG--------------------HLTKHEIGYCVTRKELLVLHEFIVHFRQYLYGRRFVARTDHKALTFMNTTKKPISPQFQTWMANFSEYDFALQYRKGNEHGNAGGWSRLNNTICSHYQMEHKDAKKAKCRTRCIN-SLQGSSNIMKIIKQKQNEDKVTSQIISHLNGNEAHISYKTISSSIFKYLKILQIQDNVLMINTDGKLAVVVPDSYVKSLVNYFHIELCHLGINKTLFYLKDFFFLPSMNQIITECINKCKICASRKIDQGRTKEILLPRTGERFLEQIVVDI--DYMETKESKKYMIVIIDCFSKLVSLP----QDEATILNVILNNWIYRFGRPESILTDRERIFEGSMFRDWMEKFGIKQEFSSPYQHQSNG 1114          

Query: 1945 ICEIEARFGRIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYL 3330
            +C I+A+FG++IT  ER   A   LKV     L EI + N+NVFMA+KW+IGCT L+KHKI+T+G  I IKPRRQPI+LE KIEEAI+NL  NGII+                             LN +T+RQA+PM N+ EILD   G ++F+SIDLGNAYYQV+L+++S+EKTAFST  GQ+CFNRMPFGIA  PGT QELM KVL ++  +G +VYL+DILIFT T+E +Y +   V+ +I                                    + EAI+SFQKP+C+KNL+SF GICNYYRRFIKDYAKK R LE +CGK N K+ W E CEKAF +MK+AL  +PVL +PDF ++FI+DTD+SFDTIG VLSQKD  G+E VIAYGSHAMS+HEKGYCI RKELLAIYYFC+HFNH+LYGKRF LRTD KAITFM++TKKPITAQF+TWIN+L
Sbjct:  113 MCNIDAKFGKLITGTERFDRARKELKVNYT-VLAEIIKNNQNVFMANKWEIGCTALLKHKIVTRGSLINIKPRRQPIHLEPKIEEAIQNLFKNGIIK----------------------------NLNLVTDRQAYPMQNIAEILDRFEGEKHFNSIDLGNAYYQVELEEKSKEKTAFSTTTGQYCFNRMPFGIATGPGTSQELMRKVLGNI--NGTVVYLNDILIFTATKEQYYAVLNDVIERIG-----------------------------------RPEAIKSFQKPECIKNLKSFPGICNYYRRFIKDYAKKTRTLEELCGKYNVKLIWAENCEKAFEDMKKALTESPVLGYPDFTRDFIIDTDSSFDTIGDVLSQKDNNGYEKVIAYGSHAMSTHEKGYCIKRKELLAIYYFCQHFNHHLYGKRFTLRTDLKAITFMLSTKKPITAQFKTWINHL 508          

Query: 1978 ITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYN 3504
             TD +RL+  +  LK+  N +L  +     N+FMA ++D+G T +I H+I           +++P++LE K+EE ++NL   G++RK  SPWNTPLV V K +   IR+CLDFR LN +TE+ +F  P++  +LD L  S+ FSSIDLG AYYQV+L++ SQ KTAFSTKEGQFCFNR+PFG++ AP TFQ+LM ++L+ L   GV+VYLD+ILI+ + +E H  +  +V  +I  +GL++NPEKC   +  + F+GH                                            +Y+  A  +      N++ I WTE C  +F  +K+ L  AP+L +P   + F++DTDASF  IGAVLSQ  E   E VIAYGS  ++ HE G+C+T KELLA++ F  HF  YLYG+RFV RTDHKA+TFM TTKKPI+ QFQTW+  LS  D  ++YRKG  H NAD  SR     C  C+ME++DAK  K +TR +  + +G  N
Sbjct:   97 FTDSDRLKITLSTLKLDKNSKLGTLISKFSNIFMASRFDLGHTKVITHEI-----------KKKPMHLEGKVEELVQNLLEAGVVRKSISPWNTPLVIVGKLDG-SIRMCLDFRLLNSVTEKFSFYSPDMKLLLDCLGNSKIFSSIDLGQAYYQVELNENSQIKTAFSTKEGQFCFNRLPFGLSTAPATFQKLMHQILEGLVFKGVVVYLDEILIYGENQEIHDKLLFEVFTRIRDSGLKVNPEKCAFNKSVLNFIGHT-------------------------------------------NYSIIAAPMYVATTGNDKMIVWTEECRNSFINLKKLLCEAPILEYPRADRLFVIDTDASFGAIGAVLSQIKEDCTEVVIAYGSRHLTKHEMGHCVTIKELLALHEFIVHFRQYLYGRRFVARTDHKALTFMNTTKKPISPQFQTWMANLSEHDFALQYRKGEEHGNADGKSRLNNTKCSHCLMENKDAKEAKCRTRYIN-SLQGSSN 549          

Query: 4018 APKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNE-GGRKNWADIVPEIEYTLNATVQKTTGVSPAEIIFGRKIDRMKWYSNKEINREDMEKRIEDKTLKPKISKTVRNFEMEDVVLIKQEIRNKDDARWEGPYKVI 4500
            +P+ +  D G  FE    ++  +  GI+  FSSPY H +N + ER  RT+R+ +  SL E   + NW  ++P IE++ NAT+Q +T  SP EI++GRKI+      + +  RE++E   E KT   K + T++N +++++     + R   +   + PY+ +
Sbjct:  615 SPESILTDRGIIFEGSMFRDWMEKFGIKQEFSSPYQHQSNILAERIIRTVRDMLATSLAEIKTKNNWCRLLPRIEFSFNATIQNSTKFSPFEIVYGRKINLYSGVEHIQKFREEIED--ETKTNLVKAATTMQNRDIDNLGTRSLKNRAYQEGIKQTPYEAL 774          

Query: 1606 GRPSTTLDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESLRCANNSRLETMGKLNINVKMGSMERNVTFIIVKNLIPEIIGGVELQRLFGIELKYILEEHEKRSDFICEIEARFGRIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESICGKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQ 3312
            GR  + + + G  V+ L D+GA I+V+++     + +  ++++R  L        E +    I  K     R +  IIV+ + P+ IGGV+  ++FG+ELK      E  +     +  RF    TD E L+  +  LK   N +L  +     N+FMA ++D G   +I H+I T   PI+   RRQ ++LE K+EE ++NL   G++RK  SPWNTPLV V K +                               D  + SR+        AYYQV+L++ SQ KTAFSTKEGQ CFNR+P G++ AP TFQ+ + + LK L   G ++YLDDILI+ + +E +  +  +V  +I  +GL+ NPEKC   +  + F+GH +++ GIQT+  KI  I++  +PK    LRSFLG+ N+Y+RFIK+Y+  A  L +                           TAP+L +P   + FI+DTD SF  IGAVLSQ  E G E VIAYGS  ++ HE  YC+TRKEL A++ F  HF  YLYGKRFV R DHKA+TFM TTKKPI++QF 
Sbjct:    5 GRKWSMMRLNGFHVEMLWDSGASISVISEKCWRLIGSPILMDSRIRLSGVFPKEDEKLLGSKIVAKWNKKFRKLNVIIVRKIYPDFIGGVDTIKIFGMELK------EVNNIESLLVNKRF----TDSELLKITLLTLKFDKNTKLGTLIFQFSNIFMASRFDFGHIKVIAHEIKTSDSPILQNSRRQLMHLEGKVEELVQNLLEAGVLRKSQSPWNTPLVIVGKPD-------------------------------DSKNVSRF-------QAYYQVELNENSQIKTAFSTKEGQLCFNRLPIGLSTAPATFQKHINQTLKGLVFKGEVLYLDDILIYAENQETYDKLLFEVFIRIRDSGLKANPEKCAFNKSVLNFIGHTVSEKGIQTNKRKISEIENATEPKSTTELRSFLGLTNFYQRFIKNYSMIAEPLYTAT-------------------------TAPILEYPRADRLFIIDTDDSFGAIGAVLSQIKEDGTEGVIAYGSRHLTEHEMEYCMTRKELFALHEFIVHFRQYLYGKRFVARMDHKALTFMNTTKKPISSQFH 500