Tor
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30006752 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of Tor vs. Ensembl Human
Match: MTOR (mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942]) HSP 1 Score: 807.749 bits (2085), Expect = 0.000e+0 Identity = 534/1592 (33.54%), Postives = 856/1592 (53.77%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALE----VPSQYIKQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSV--DQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSVRSI--LELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S+ CR L+ K + + Q +++ + K+ LIQ+TI + +PRLAA +QY++ +++ + C+KKEK ++ +G ++ EF+ +L + + I+ LP KD + K+++ + ++ +++ I ++A + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + L+ + + + +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + + + VADVL KLL+V +DP+ D+R CV S DERFDA+LAQ +L LFVA D++FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG R KEQ+A++L L+ AP ++ + E +L L+ +++ PD P G +++N++AT I LA V G ++RK + +L ++ M+QDS+ L KR VA+ TL +LV TGYVVEPYRK+P LL +LL L+TE+ RRE I++LG +GALDP+K K +D D V + D S +E+LVN LD+FY A ++ +L ++ RD + ++ + I IFK LG VQ+L QV+P + I D ++ QL ++ VK H++ +M +++ ++ + W + + I L++ + + LG + K +L L+ + + D G + SI L + F ++++++H+LLP I+K+ + L +KAAL+ + RL E+LD +D A RI+ P+ R LD Q EL A D L++L+ ++ +++ + P++ K L ++ R++ + +++K +++ E++ ++ R R ++T ++++NLQKAW A + +S DDW++WL+ S+ L K+S S ++RSC L +++ LFNA+FVSCW EL + QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG P IL L++INNKLQ EAA+GV+ YA K + +L+ + W+E L +W AL Y +K++ N + EL LGRMRCL+ALG+W L +++ V+D + KMA + AAW LG +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V L+ELEEVIQYKLV E +E IRQ W +RL+GCQ++++DW+++L +RSLV++P++DM TWLK+A L +S RL ++ + L G + S+ ++ L PQ+ +++ K W + + A +++ V+ + + + I D+ + L+A+C L+LG+W + LQY Y ATE +AW AWA+ N+ + K++
Sbjct: 359 SRCCRDLMEEKFDQVCQWVLKCRNSKNS-LIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKV--YLPRVLDIIRAALPPKDFAHKRQKAMQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKD--------PD----------------------------PDPNPG---VINNVLAT----------------IGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVI-RVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPE--APLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLD---------------------------QSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVL----------VRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQH--RMLRSGQGDALASGPVETGPMKKLH-VSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEF-----QKGPTPA-ILESLISINNKLQQPEAAAGVLEYAMKHF-GELEIQATWYEKLHEWEDALVAYDKKMDTNKD----DPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSR-QLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQ-------TMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQY-----YSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQ 1807 HSP 2 Score: 653.284 bits (1684), Expect = 0.000e+0 Identity = 311/574 (54.18%), Postives = 420/574 (73.17%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSAN 8109
Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M HS LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF++L PLH +MER +T E +F Y DL A+ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLT++G +GH ++FLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L ++QK EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++++S++AVLEAF++DPLL W L D KG + + DS SA
Sbjct: 1880 YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAG 2452 HSP 3 Score: 80.8777 bits (198), Expect = 4.775e-14 Identity = 49/208 (23.56%), Postives = 110/208 (52.88%), Query Frame = 1
Query: 88 IDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
+ + F +GLK++++E + K AKE +++V EL++ S EE F D++ ++ S+D NERK ++ + ++ ++ + + + + ++++ +ND + + ++ I + + + E VE ++K + + D ++EG+R A L+ +E++ T FFQ +++ + + D + ++RE AL +T RE
Sbjct: 19 VSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEG-GNATRIGRFANYLRNLLPSNDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQRE 224 HSP 4 Score: 55.4546 bits (132), Expect = 2.063e-6 Identity = 22/56 (39.29%), Postives = 36/56 (64.29%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGGN--LTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ + L V++L+KQAT + NLCQ Y GWC FW
Sbjct: 2494 NKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW 2549
BLAST of Tor vs. Ensembl Human
Match: MTOR (mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942]) HSP 1 Score: 646.351 bits (1666), Expect = 0.000e+0 Identity = 318/615 (51.71%), Postives = 437/615 (71.06%), Query Frame = 1
Query: 6265 NENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSAN 8109
N + E++ +P+ L Q ++ + K L++ Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M HS LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF++L PLH +MER +T E +F Y DL A+ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLT++G +GH ++FLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L ++QK EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++++S++AVLEAF++DPLL W L D KG + + DS SA
Sbjct: 53 NSESEAESTENSPTPSPL-----QKKVTEDLSKTLLM----YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAG 657 HSP 2 Score: 55.4546 bits (132), Expect = 1.870e-6 Identity = 22/56 (39.29%), Postives = 36/56 (64.29%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGGN--LTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ + L V++L+KQAT + NLCQ Y GWC FW
Sbjct: 699 NKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW 754
BLAST of Tor vs. Ensembl Human
Match: SMG1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:HGNC Symbol;Acc:HGNC:30045]) HSP 1 Score: 219.164 bits (557), Expect = 6.561e-56 Identity = 180/649 (27.73%), Postives = 297/649 (45.76%), Query Frame = 1
Query: 6457 SLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKS----------------------------------GGSDRRRYNANK--------------------ILHSMEVHSARLVSEAFLLNEELIRLGISWMEMW--------------TECLEDASR-------LHYEEK-------NTTAMFKILYPL-HI--LMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAW----EIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVS-NRQ-TSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEML------------------KIAPDFEKLNI------------IQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
+LRL+ LL + H +R+ + GL W +I QL +R++ + +V I LL V + P ++ P ++ S GGS ++NK I+ + + +V + +L EL R+ + W E+W + LED + L EEK +T M I++ L H+ + ET HE ++ + YGD + +N + ++ +W EI +L ++ K+ S + L L SP L + +A+PG R V I+S+ + ++ +K P+KL +G DG +Y +L KG ED+ DER MQF ++NT+ + NRQ T R + + SV PL T +GLI WV + L + + ++++ L ++ ++ KI P + + + + K V E + + LA LW + W+ ++ RS AVMSMVGYI+GLGDRH N+++ +G+V+HID+ CFE + PEKVPFR+T+ + A+ VTG+EG+FR + Q++++MR+ RE+LL +LEAF++DPL+ W
Sbjct: 1789 TLRLLRLLVK--HAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHE-KWFQDNYGD--AIENALEKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYI--LRLEEISPWLAAMTNTEIALPGEVSA-RDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFH--ARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKA-VLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSL-RVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDW 2425
BLAST of Tor vs. Ensembl Human
Match: SMG1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:HGNC Symbol;Acc:HGNC:30045]) HSP 1 Score: 219.164 bits (557), Expect = 6.760e-56 Identity = 180/649 (27.73%), Postives = 297/649 (45.76%), Query Frame = 1
Query: 6457 SLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKS----------------------------------GGSDRRRYNANK--------------------ILHSMEVHSARLVSEAFLLNEELIRLGISWMEMW--------------TECLEDASR-------LHYEEK-------NTTAMFKILYPL-HI--LMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAW----EIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVS-NRQ-TSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEML------------------KIAPDFEKLNI------------IQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
+LRL+ LL + H +R+ + GL W +I QL +R++ + +V I LL V + P ++ P ++ S GGS ++NK I+ + + +V + +L EL R+ + W E+W + LED + L EEK +T M I++ L H+ + ET HE ++ + YGD + +N + ++ +W EI +L ++ K+ S + L L SP L + +A+PG R V I+S+ + ++ +K P+KL +G DG +Y +L KG ED+ DER MQF ++NT+ + NRQ T R + + SV PL T +GLI WV + L + + ++++ L ++ ++ KI P + + + + K V E + + LA LW + W+ ++ RS AVMSMVGYI+GLGDRH N+++ +G+V+HID+ CFE + PEKVPFR+T+ + A+ VTG+EG+FR + Q++++MR+ RE+LL +LEAF++DPL+ W
Sbjct: 1679 TLRLLRLLVK--HAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHE-KWFQDNYGD--AIENALEKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYI--LRLEEISPWLAAMTNTEIALPGEVSA-RDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFH--ARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKA-VLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSL-RVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDW 2315
BLAST of Tor vs. Ensembl Human
Match: ATR (ATR serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:882]) HSP 1 Score: 182.185 bits (461), Expect = 8.399e-45 Identity = 144/480 (30.00%), Postives = 238/480 (49.58%), Query Frame = 1
Query: 6691 KSGGSDR--RRYNANKILHSMEVHSARLVSEAFL--LNEELIRLGISWMEMWTECLEDASR--LHYEEKNT---TAMFKILYPLHILMEREI--ETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLEL-----SVASPRLHDYNDWILAIPGSYDPNRPI----VKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVI-RDYREKTQVLLNREHKEML--KIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSH-NSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDF------GDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
K+G SDR R + KI + H+ L FL ++ + R+ S E++ +E ++ L Y ++ TA+ K YP+ + +EI + H ++ GD + + + E N D + + S ++ K + + E+ SV P L IL ++ + P I + + ++ S Q P+K+++ G DG Y+ + K +D+R+D R M+F LIN + + ++ R L I+ +VIPL+ G+I WV N+ L ++ + Y+EK + +E ++ + K A EKL + ++ + + H +L++ + +W+ R+ + RS AVMSMVGYILGLGDRH NI+ +G+ +H+DF G+ FEV PE VPFRLT ++ M G EGLFR + LMR RE L++VL+ FLHDPL++W
Sbjct: 1703 KAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTDKLL--ELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPS----ILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFREFLL-------PRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEV-------PEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW 2162
BLAST of Tor vs. Ensembl Celegans
Match: let-363 (Target of rapamycin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q95Q95]) HSP 1 Score: 538.11 bits (1385), Expect = 6.307e-154 Identity = 265/568 (46.65%), Postives = 385/568 (67.78%), Query Frame = 1
Query: 6400 AVRGFVNAISLSPTANLQDSLRLVILLFQF--DHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVS-SIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIET-HHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREK-TQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVET 8088
AVR F A+ SP + L+D+LRL+ L F D + + + + + + WL I QL+AR+D + S +++ +L + PQA++ L +A +S R + NA +L M + ++LV EA L+ EEL+R I W E W + L+DASR+++ + N AMF L ++ LM++ T E +F Y DL A +ESS DL QAWEIY ++++K Q++ +++L+L SP L D L +PG+YDP+ PIV I S + +N++TSKQ PRK+ I G +G +Y FLLKGHED RQDER MQ FGL+NTL+ +N +T R NL+IQR S++ LS ++GLIGWVPN DTL+ ++++YREK ++ L+ EHK + K++ + E L ++QK ++FES + + G+DL H+LWLKS +SE WF+RRTN+ RS+A MSMVGYILGLGDRHPSN+ML R +GKV+HIDFGDCFEVA +REK+PE+VPFRLTRMLI AMEVTG++G++ +T+ +++ ++R N+ESLLAVLEAF++DP++ W L + KK + +T
Sbjct: 2051 AVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSK-NAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHDNNVQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDT 2617 HSP 2 Score: 266.929 bits (681), Expect = 7.576e-71 Identity = 203/688 (29.51%), Postives = 322/688 (46.80%), Query Frame = 1
Query: 4126 SNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMT---------QEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPEL-TDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETA-------KKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNEL-------------------TLGRMRCLQALGDWSSLKNIGI-------DRFDQVDDSIKTK-----MAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQF----PQIIFSWSKYQWTTGQHQMALGNLELLVEQ--KLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDW----------------------------YTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSK 5943
++ +DN D + + +++ S VP + T+ + Q +N L W + + S D+W+QWL I S ++R+ S+LG L++ LF A+F+S W EL +D Q D L +I P E+ Q +LNL EFM H E+ LPI+ L A + + +AKA YKE L+++ +K N L+T NKL ++E A+GVV YA + + Q RW+E L +W KAL Y+ LE+ N ++ + MRCL+ALG W L + + +R D V D I K MA I AWA+ ++ M YV I N +G LRAV+A+ ++E +A I+K R+ +DS LTAMA ESY RAY +V Q++AELEE I+YK E + I W RL+GC++ ++ W++L+ +R LVL+P + +KF+ + R+ + MS++++ L LS + ++++ + P ++ + +K + A+ LE L K N I T R +++ S + +RI AK L+LG+W ES ET A + + Y Y+ AT+ PG + W A ++ +C +
Sbjct: 1277 ASRQDNRDDYYRYGVEEKI---SEEVPKVAPTTARPTSELVTVQITKQRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDLFPAAFMSVWTELDSDVQNDLTSCLLRAISTGIP--ELIQTILNLAEFMDHSEKGPLPISHDVLGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEAAGVVRYAERNEMN-FQMRGRWYEKLNEWEKALGAYE--LEEKKKSSCPNLQVYDEKDHLMTPEEAATAEEARMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIAARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLREL----LSLPANSDLVRAKAPFDKPLLVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGR----ELIPPSTKEPARI-CAKVLLKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINY-----YQQATQYDPGWHKVWHKLASTHFYAVCRER 1942 HSP 3 Score: 223.016 bits (567), Expect = 1.573e-57 Identity = 189/761 (24.84%), Postives = 355/761 (46.65%), Query Frame = 1
Query: 1582 YMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNN---SRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDER---FDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELL--VNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRH----QQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTL-VDALEGSVRS--ILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQ 3819
+ + L + +V IK +I ++++ LS L LKM+ + IP+L ++ ++ S+ +TL + ++EP S L+ D E + ++A+ L EF F + L +++++ ++T E+RL AV +C +++ P +G S + L + VL + V +D + VR+ V F + F A+LAQ L F+A +DE E+++ + LGRL+ +NP+ + P LR +LL+TL++++ SG +R ++ +A+++A+L +P F++ P + S++ A MIP R E TA V+ A+ +AV+ G+++ K+L L L +M+ DS+SL KR A+ + + T YVV+PYR +P LL LL +L+T ++RRE IK LG +GA+DP+ K F + S + +S+ I + + + +++ N + L++FY A + +L +++D +S Y I I++IF+ LG + Y +QV+P A ++ + ++ FL QL +++ H +MP + I+ W + + +V I++L + +G D + L+ L D + V + ++E + + + I +H+ L +I ++ L I+ AL + + + +D+S A R++Q
Sbjct: 482 FTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMASVYQTLTGSLIPPKSEPIGRPASPKAILQKA----------------ETDPKELQRIVLAVDVLGEFYFSRGALQRIMQYVAD---YYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRLAELNPALVLPRLRLMLLETLSQMQQSGQARLEQHSAKMIAQLAKQSPKFMR-----------PYVGSLMIA--------------------------------MIPKLRND-----------QKYAEVTA---QVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHKVFTGSVQSSTAISTALSL--PISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQDEDSQS-YAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQLANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESIQKLTHCIVQHL--HLVLPPLLIILDDFSLKLSIRNTALSTVLHMTQQVDVSAYAPRMMQ 1161
BLAST of Tor vs. Ensembl Celegans
Match: let-363 (Target of rapamycin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q95Q95]) HSP 1 Score: 538.11 bits (1385), Expect = 6.367e-154 Identity = 265/568 (46.65%), Postives = 385/568 (67.78%), Query Frame = 1
Query: 6400 AVRGFVNAISLSPTANLQDSLRLVILLFQF--DHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVS-SIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIET-HHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREK-TQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVET 8088
AVR F A+ SP + L+D+LRL+ L F D + + + + + + WL I QL+AR+D + S +++ +L + PQA++ L +A +S R + NA +L M + ++LV EA L+ EEL+R I W E W + L+DASR+++ + N AMF L ++ LM++ T E +F Y DL A +ESS DL QAWEIY ++++K Q++ +++L+L SP L D L +PG+YDP+ PIV I S + +N++TSKQ PRK+ I G +G +Y FLLKGHED RQDER MQ FGL+NTL+ +N +T R NL+IQR S++ LS ++GLIGWVPN DTL+ ++++YREK ++ L+ EHK + K++ + E L ++QK ++FES + + G+DL H+LWLKS +SE WF+RRTN+ RS+A MSMVGYILGLGDRHPSN+ML R +GKV+HIDFGDCFEVA +REK+PE+VPFRLTRMLI AMEVTG++G++ +T+ +++ ++R N+ESLLAVLEAF++DP++ W L + KK + +T
Sbjct: 2054 AVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSK-NAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHDNNVQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKKDPKTRKDT 2620 HSP 2 Score: 266.929 bits (681), Expect = 7.909e-71 Identity = 203/688 (29.51%), Postives = 322/688 (46.80%), Query Frame = 1
Query: 4126 SNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMT---------QEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPEL-TDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETA-------KKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNEL-------------------TLGRMRCLQALGDWSSLKNIGI-------DRFDQVDDSIKTK-----MAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQF----PQIIFSWSKYQWTTGQHQMALGNLELLVEQ--KLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDW----------------------------YTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSK 5943
++ +DN D + + +++ S VP + T+ + Q +N L W + + S D+W+QWL I S ++R+ S+LG L++ LF A+F+S W EL +D Q D L +I P E+ Q +LNL EFM H E+ LPI+ L A + + +AKA YKE L+++ +K N L+T NKL ++E A+GVV YA + + Q RW+E L +W KAL Y+ LE+ N ++ + MRCL+ALG W L + + +R D V D I K MA I AWA+ ++ M YV I N +G LRAV+A+ ++E +A I+K R+ +DS LTAMA ESY RAY +V Q++AELEE I+YK E + I W RL+GC++ ++ W++L+ +R LVL+P + +KF+ + R+ + MS++++ L LS + ++++ + P ++ + +K + A+ LE L K N I T R +++ S + +RI AK L+LG+W ES ET A + + Y Y+ AT+ PG + W A ++ +C +
Sbjct: 1277 ASRQDNRDDYYRYGVEEKI---SEEVPKVAPTTARPTSELVTVQITKQRLNKDALMPQWKNENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDLFPAAFMSVWTELDSDVQNDLTSCLLRAISTGIP--ELIQTILNLAEFMDHSEKGPLPISHDVLGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEAAGVVRYAERNEMN-FQMRGRWYEKLNEWEKALGAYE--LEEKKKSSCPNLQVYDEKDHLMTPEEAATAEEARMHEMRCLEALGRWDELNSKSVVWADQRGNRNDSVRDEINKKQLDHKMAVIAARGAWAVDNWERMADYVSVISENTQDGAMLRAVVAVHNDENTKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEYKTRPERRPRIALLWSRRLQGCRRNVEQWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQGKNSMSRAVLREL----LSLPANSDLVRAKAPFDKPLLVLALAKQLYQDDHKDEAIRALEDLANHWNKRINPIPKATGR----ELIPPSTKEPARI-CAKVLLKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESRTPETIAFENTINY-----YQQATQYDPGWHKVWHKLASTHFYAVCRER 1942 HSP 3 Score: 223.016 bits (567), Expect = 1.600e-57 Identity = 189/761 (24.84%), Postives = 355/761 (46.65%), Query Frame = 1
Query: 1582 YMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNN---SRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDER---FDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELL--VNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRH----QQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTL-VDALEGSVRS--ILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQ 3819
+ + L + +V IK +I ++++ LS L LKM+ + IP+L ++ ++ S+ +TL + ++EP S L+ D E + ++A+ L EF F + L +++++ ++T E+RL AV +C +++ P +G S + L + VL + V +D + VR+ V F + F A+LAQ L F+A +DE E+++ + LGRL+ +NP+ + P LR +LL+TL++++ SG +R ++ +A+++A+L +P F++ P + S++ A MIP R E TA V+ A+ +AV+ G+++ K+L L L +M+ DS+SL KR A+ + + T YVV+PYR +P LL LL +L+T ++RRE IK LG +GA+DP+ K F + S + +S+ I + + + +++ N + L++FY A + +L +++D +S Y I I++IF+ LG + Y +QV+P A ++ + ++ FL QL +++ H +MP + I+ W + + +V I++L + +G D + L+ L D + V + ++E + + + I +H+ L +I ++ L I+ AL + + + +D+S A R++Q
Sbjct: 482 FTFLFLFVDAYHEQVTTQIKAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMASVYQTLTGSLIPPKSEPIGRPASPKAILQKA----------------ETDPKELQRIVLAVDVLGEFYFSRGALQRIMQYVAD---YYLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSLLQTIYGVLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRLAELNPALVLPRLRLMLLETLSQMQQSGQARLEQHSAKMIAQLAKQSPKFMR-----------PYVGSLMIA--------------------------------MIPKLRND-----------QKYAEVTA---QVLNAVSEIAVIGGAEIVKNLKPLFEKLTHMINDSSSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHKVFTGSVQSSTAISTALSL--PISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQDEDSQS-YAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQLANFVAIIRKHAAPYMPAIFTIIADAWKEDISVKMVVIEVLTDMGTAIGNDFSKYTGELIPYLLTVLQTDKTKERVLTVKVMESIQKLTHCIVQHL--HLVLPPLLIILDDFSLKLSIRNTALSTVLHMTQQVDVSAYAPRMMQ 1161
BLAST of Tor vs. Ensembl Celegans
Match: smg-1 (Serine/threonine-protein kinase smg-1 [Source:UniProtKB/Swiss-Prot;Acc:O01510]) HSP 1 Score: 197.208 bits (500), Expect = 9.829e-50 Identity = 167/614 (27.20%), Postives = 285/614 (46.42%), Query Frame = 1
Query: 6457 SLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSD-------------RRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWT--------ECLEDASRLHYEEKNT------TAMFK--ILYPLHILMEREI-----ETHHEVAF-----YNEYYGDLSSAKNLCIRYESS--NYKTDLTQAWEIYSNLYRKWSKQISN--VSTLELSVASPRLHDYNDWILAIPG--SYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRM---SVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKL-----NIIQKT-----------------------EVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGG 8070
+LR++ LL + H + +VI DGL+K ++ W ++ QL AR+ EH+ +V L+ + P A+V +V S +D R R K+ +M LV + EL R+ + E W+ E + S + E T TA K I+ L+ R+I E + + NE + A+ L ++ S + T ++W + NL + + S + T E SP L ++ + +PG S + +R +V I+ + + ++ +K P+KL +G DG FL KG ED+ DER MQF L N ++ + R +++ + +VIPL +GLI WV + + + R ++ K + L + K+ + P+ E+ N+I+ EVFES ++ ++ LW++++++ W+ + RSLAVMSMVG +LGLGDRH N+++ G V+HID+ CF+ + PE VPFRLTR + A+ + + G FR + + +++ +R + L +L+AF+ DPL+ W H++T G
Sbjct: 1458 TLRILELLVK--HGDVLIDVINDGLNKTNVHIWKEILPQLFARLSHPSEHIRKTLVDLISKICTAAPHAVVFQVVSGAASSSTDGEELEEQQNDDRNRVRACCEKLETNMSQSYPNLVKDVRQFVAELERINLLNEEKWSVVMGTMEHEMEKRLSLIRTENAKTESALHLTASVKNDIIVKRTQLLTRQIFDVLDELYQQTVIEPPKSKNEEEFVTAFAEVLTNAFQESRISRTTSPEKSWIPFKNLIANFVHRNSKKGMQTFETEDISPYLASLSNSCVPMPGQESVEFDR-VVSISRVARQVTILPTKTRPKKLGFVGSDGKQVAFLFKGREDLHLDERVMQFLRLCNVMLQPGKGKHRQSVAAYQAHHYAVIPLGPRSGLIKWVEGATPMFHIYRKWQMKEKA-LKQATKKNGETVPEIERPSNMYHNMIRLAFADHKIDSSITSDRSKWPAEILEEVFESLTAKTPTDLISRELWMRANDATTWWSVTKRYSRSLAVMSMVGSVLGLGDRHLDNLLVDLKWGHVVHIDYNICFDKGK-NLRIPETVPFRLTRNMRHALGPSEMYGTFRESCVHVLSTLRSGHQVLTMLLDAFVFDPLVDWTSHEHTATSG 2066
BLAST of Tor vs. Ensembl Celegans
Match: atl-1 (Serine/threonine-protein kinase ATR [Source:UniProtKB/Swiss-Prot;Acc:Q22258]) HSP 1 Score: 100.138 bits (248), Expect = 1.630e-20 Identity = 76/270 (28.15%), Postives = 127/270 (47.04%), Query Frame = 1
Query: 7189 PNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKI-APDFEKLNIIQKTEVFESGIRESDGKDLAHIL--WLKSHNSEA--WFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKN 7983
P+R + I+ + + ++ S P + + G + K +D+ +D + + N L++ + QT ++ SVIPL G+I ++ + + +K + + E E LK + + ++T+ F RE K+ ++ W + EA WF R F +S AVMS++GYI GLGDRH N+M+ +GK IH+DF F PE VPFRLT+ +I M ++G FR Q + + R+N
Sbjct: 710 PDRYL--IHDFSDKVKVLHSNTKPVIIKLTTKTGRIVRLICKKDDDLSKDYHFTKMVEMCNDLLMKDEQTRIQKMTATTYSVIPLGKQGGIIEFMEGVTSFYETL----DKLMGMTSGEWLEKLKFWNTHMKPMGKEERTKYF----REVACKNTPVVMGKWFRIQYPEAGQWFASRKLFAKSTAVMSVIGYIFGLGDRHTKNLMV-HTTGKCIHVDFDMIFNKGETL-GTPELVPFRLTQNMINGMGEVALDGEFRTVCEQALRVFREN 967
BLAST of Tor vs. Ensembl Celegans
Match: atl-1 (Serine/threonine-protein kinase ATR [Source:UniProtKB/Swiss-Prot;Acc:Q22258]) HSP 1 Score: 99.3673 bits (246), Expect = 4.051e-20 Identity = 76/270 (28.15%), Postives = 127/270 (47.04%), Query Frame = 1
Query: 7189 PNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKI-APDFEKLNIIQKTEVFESGIRESDGKDLAHIL--WLKSHNSEA--WFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKN 7983
P+R + I+ + + ++ S P + + G + K +D+ +D + + N L++ + QT ++ SVIPL G+I ++ + + +K + + E E LK + + ++T+ F RE K+ ++ W + EA WF R F +S AVMS++GYI GLGDRH N+M+ +GK IH+DF F PE VPFRLT+ +I M ++G FR Q + + R+N
Sbjct: 2167 PDRYL--IHDFSDKVKVLHSNTKPVIIKLTTKTGRIVRLICKKDDDLSKDYHFTKMVEMCNDLLMKDEQTRIQKMTATTYSVIPLGKQGGIIEFMEGVTSFYETL----DKLMGMTSGEWLEKLKFWNTHMKPMGKEERTKYF----REVACKNTPVVMGKWFRIQYPEAGQWFASRKLFAKSTAVMSVIGYIFGLGDRHTKNLMV-HTTGKCIHVDFDMIFNKGETLGT-PELVPFRLTQNMINGMGEVALDGEFRTVCEQALRVFREN 2424
BLAST of Tor vs. Ensembl Fly
Match: Tor (gene:FBgn0021796 transcript:FBtr0080422) HSP 1 Score: 756.133 bits (1951), Expect = 0.000e+0 Identity = 497/1562 (31.82%), Postives = 831/1562 (53.20%), Query Frame = 1
Query: 1300 KHPYLIQLTIHAIPRLAALE---VPSQYIKQSLDFLHRCIK---KEKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHL--GDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLVDALEGS---VRSILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNRI 5952
K PY+ Q + +PRLAA +Y++ + L + ++ K++ ++YIT+G++A E + L +T++K+ LP KD+++K++ P+ + +++ I L+A K+++ +K+++ M GLS L L+ +S +P+L + I L+ L + LMN + P A + +I + +L+ NG + ++AL+TL F+F++ N+ FV+ + FI +E+RLEAV+TC +LL L E + + V+ V+E+LL+V+ +D + +VR+ + +S DE FD LAQ L+ LF+ +DE+FEIR+L + +GRLS+INP+ + P LR +++ +T+L++SG SRNKEQ+A++L L+ + P + S+ +L L+P++ +P+ +NP V L V++ I +LA V G L DL+ L+ M+ D+ S DKR VA+ TL +L++ TG VV PY K+P L+ +L+ L+TE+ SIRRE I++LG +GA+DP+K K +DS D L+ +++ + D+S AELLVN LD++Y A A+ +L ++LRDPT + + + + IF+ LG V YL QVLP + A DN ++ QL I+ VKLH+ +M + +++ + W + L I L++ + + LG + + +L+ L+ + L R +L+ L +F ++ ++ ++LP I+K+ + Q+ AL+ + LA LD +D + RI+ P+ R+LD +EP EL A L +L ++ ++++V P++Q+TL + P + L+K+ S ++ D+ ES R R +N+ P + D + + ++ + L+ AW + +S DDW++WLK SI L KESPS+A+R+C +L L + LFNA+F+SCW EL+ ++ L +L L E++Q +LNL EFM HC+R +PI T L +RA+ R YAKAL YKE+EFL + + L+ INNKLQ EAA G+ L + ++L + RW+E L +W +AL Y+R L+ + S + E LG MRCL+ALGDWS L N+ ++ K++ P+ AAW L D+ M +YV IP + +G + RAV+A+ H++F A I + RD LD+ LT+MAGESY RAYG +V Q LAELEEVIQYKL+ E +E ++ W RL+G Q++++DWR+++Q+ SLV+ P++D+ TWLK+A L R+S L +S + L G++ K++ N L C PQ+ ++++KY Q Q A ++L + + ++ ++ + E+ + + L+A+C LR+ W K D++ + + + AT P +AW WA N+ ++ K+ +
Sbjct: 369 KSPYVQQALLQILPRLAAFNRAVFVEKYLQTCVSHLMQILRGKEKDRTVAYITIGYMAVAVQSAIEVH--LSSIMTSVKVALPSKDLTSKRKVPV-DPAVFACITLLAHAVKSEIADDVKDILEQMFYTGLSPALTVCLRELSENVPQLKSAITEGLIGILSQVLMNKAAILPYTALPTIAI---DGSLMQNG---------------DGATTVLALKTLGTFNFEEQNMLDFVQRCAD---YFIVHEQQEIRLEAVQTCTRLLK--LAVQSSESMENSKTLSDTVSHVIERLLMVAITDMDCNVRIRILRSLDETFDGKLAQPESLNSLFITLHDEIFEIRELAMVTIGRLSSINPAYVMPKLRTTMIELITDLKYSGMSRNKEQSAKMLDHLVISTPRLISSYMNPILKALVPKLH--------EPE--------------------------------------------SNP-----GVILNVLRTIGDLAEVNGGSDEMELWADDLLSILLEMLGDAGSPDKRGVALWTLGQLISATGRVVTPYHKYPVLIDILINFLKTEQRRSIRRETIRVLGLLGAMDPYKHKMNKGLIDSQKDNVLIAYSDGKVDESQ-DISTAELLVNMG-NALDEYYPAVAIAALMRILRDPTLSTRHTSVVQAVTFIFQSLGIKCVPYLAQVLPNLLDNVRTA-DNNLREFLFQQLAILVAFVKLHIISYMGDIFKLIKEFWTINTPLQNTLINLIEQIAVALGCEFRDYLAELIPQILRVLQHDNSKDRMVTRRLLQALQKFGSTLGYYLPLILPPIVKLFDSPYVPQ--QVSMVALETINNLACQLDFTDFSSRIIHPLVRVLD-AEP--------------------------ELRDQAMTTLRSLAKQLGKKYLVFVPMVQRTLNKHRIVDP----------EYEELLSKIKSCSTLA---DSYGAGESELRPSRFKNNE---PFVTDRNSNNKNLQVTTNELRTAWQVTRRVSKDDWVEWLKRLSIGLLKESPSHALRACRSLAQEYDTLLRDLFNAAFISCWTELSPDLKNELTQSLIQALQVTDMPEITQTILNLAEFMEHCDRDPIPIETKLLGTRAMACRAYAKALRYKEEEFLLREDSQ------VFESLILINNKLQQREAAEGL-LTRYRNAANELNVQGRWYEKLHNWDEALEHYERNLKTDSS----DLEARLGHMRCLEALGDWSELSNVTKHEWENFGTEAKSRAGPLAAVAAWGLQDWEAMREYVRCIPEDTQDGSYYRAVLAVHHDDFETAQRLIDETRDLLDTELTSMAGESYERAYGAMVCVQMLAELEEVIQYKLIPERREPLKTMWWKRLQGGQRLVEDWRRIIQVHSLVVKPHEDIHTWLKYASLCRKSGSLHLSHKTLVMLLGTD-PKLNPNQPLPCNQPQVTYAYTKYMAANNQLQEAY--------EQLTHFVSTYSQELSCLP--PEALKQQDQRLMARCYLRMATWQN----KLQDSIRPDAIQGALECFEKATSYDPNWYKAWHLWAYMNFKVVQAQKSAL 1773 HSP 2 Score: 632.484 bits (1630), Expect = 0.000e+0 Identity = 306/569 (53.78%), Postives = 415/569 (72.93%), Query Frame = 1
Query: 6367 LIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGE 8073
+I++R Y+ PAV+GF +ISL +LQD+LRL+ L F + + + + E + G+ I + WL VI QL+ARIDTH++ V +I LL+ +G+ HPQA+V PL +A KS S RR A KIL SM HS LV +A + +EELIR+ I W E W E LE+ASRL++ ++N MF+IL PLH ++ER +T E +F Y +L+ A RY++S DL +AW+IY ++++K S+Q+ +++LEL SP+L D LA+PGSY+P + +++I+ IK L ++TSKQ PRKL I G +G +YM+LLKGHED+RQDER MQ F L+NTL++ + T R NL+IQR +VIPLSTN+GLIGWVP+ DTL+ +IRDYR+K +V LN+EH+ ML APD++ L ++QK EVFE + ++ G DLA +LWLKS +SE WFERR N+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRMLI AMEVTGIEG +R T ++ ++R+N++SL+AVLEAF++DPLL W L D KKG +
Sbjct: 1796 MIIQR--YAVPAVQGFFRSISLIKGNSLQDTLRLLTLWFDYGNHAEVYEALLSGMKLIEINTWLQVIPQLIARIDTHRQLVGQLIHQLLMDIGKNHPQALVYPLTVASKSA-SLARRNAAFKILDSMRKHSPTLVEQAVMCSEELIRVAILWHEQWHEGLEEASRLYFGDRNVKGMFEILEPLHAMLERGPQTLKETSFSQAYGRELTEAYEWSQRYKTSAVVMDLDRAWDIYYHVFQKISRQLPQLTSLELPYVSPKLMTCKDLELAVPGSYNPGQELIRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIRDYRDKKKVPLNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNWRLLDVDKKGND 2361 HSP 3 Score: 83.1889 bits (204), Expect = 4.466e-15 Identity = 60/255 (23.53%), Postives = 123/255 (48.24%), Query Frame = 1
Query: 79 MTPIDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDF-IFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLISSPEKVES---QIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAAREGIGRRRQ----KVINDTTNQNTASSKLPMVSLGSSQFQKQISQ 819
M+ V F+ GLK+++ ++ K ++ +V EL++ S EE+ F D+ +M+ + DINE+K + M C+++ + + + S ++D+ + ND+ + + AR + + + + + +S IK++ V+ + + E +R A + +E++ T F+Q + I D + ++RE AL A VTA RE + + ++ D N + + LGSS+ QK +++
Sbjct: 1 MSTTSVVQQFVNGLKSRNRNVQNKATQDLLFYVKTELREMSQEELAQFFDEFDHHIFTMVNATDINEKKGGALAMKCLINCEGSLTARKGISPYLNRLRDLLLINDVSVMEIAARSLVKLANMPTSKGADSFDFDIKKAFEVLRGE-RQEYRRHSAVFILRELAIALPTYFYQHILTFFEVIFNAIFDPKPAIRESAGEALRAALIVTAQRESTKQSSEPQWYRICYDEANGSFNA------DLGSSKDQKGVTR 248 HSP 4 Score: 55.4546 bits (132), Expect = 1.166e-6 Identity = 24/56 (42.86%), Postives = 35/56 (62.50%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGK--EVGGNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A V+K +K KL G + ++ + V++L++QAT N NLCQ Y GWC FW
Sbjct: 2415 NSKASQVIKRVKCKLTGTDFQTEKSVNEQSQVELLIQQATNNENLCQCYIGWCPFW 2470
BLAST of Tor vs. Ensembl Fly
Match: Tor (gene:FBgn0021796 transcript:FBtr0336615) HSP 1 Score: 756.133 bits (1951), Expect = 0.000e+0 Identity = 497/1562 (31.82%), Postives = 831/1562 (53.20%), Query Frame = 1
Query: 1300 KHPYLIQLTIHAIPRLAALE---VPSQYIKQSLDFLHRCIK---KEKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHL--GDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLVDALEGS---VRSILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNRI 5952
K PY+ Q + +PRLAA +Y++ + L + ++ K++ ++YIT+G++A E + L +T++K+ LP KD+++K++ P+ + +++ I L+A K+++ +K+++ M GLS L L+ +S +P+L + I L+ L + LMN + P A + +I + +L+ NG + ++AL+TL F+F++ N+ FV+ + FI +E+RLEAV+TC +LL L E + + V+ V+E+LL+V+ +D + +VR+ + +S DE FD LAQ L+ LF+ +DE+FEIR+L + +GRLS+INP+ + P LR +++ +T+L++SG SRNKEQ+A++L L+ + P + S+ +L L+P++ +P+ +NP V L V++ I +LA V G L DL+ L+ M+ D+ S DKR VA+ TL +L++ TG VV PY K+P L+ +L+ L+TE+ SIRRE I++LG +GA+DP+K K +DS D L+ +++ + D+S AELLVN LD++Y A A+ +L ++LRDPT + + + + IF+ LG V YL QVLP + A DN ++ QL I+ VKLH+ +M + +++ + W + L I L++ + + LG + + +L+ L+ + L R +L+ L +F ++ ++ ++LP I+K+ + Q+ AL+ + LA LD +D + RI+ P+ R+LD +EP EL A L +L ++ ++++V P++Q+TL + P + L+K+ S ++ D+ ES R R +N+ P + D + + ++ + L+ AW + +S DDW++WLK SI L KESPS+A+R+C +L L + LFNA+F+SCW EL+ ++ L +L L E++Q +LNL EFM HC+R +PI T L +RA+ R YAKAL YKE+EFL + + L+ INNKLQ EAA G+ L + ++L + RW+E L +W +AL Y+R L+ + S + E LG MRCL+ALGDWS L N+ ++ K++ P+ AAW L D+ M +YV IP + +G + RAV+A+ H++F A I + RD LD+ LT+MAGESY RAYG +V Q LAELEEVIQYKL+ E +E ++ W RL+G Q++++DWR+++Q+ SLV+ P++D+ TWLK+A L R+S L +S + L G++ K++ N L C PQ+ ++++KY Q Q A ++L + + ++ ++ + E+ + + L+A+C LR+ W K D++ + + + AT P +AW WA N+ ++ K+ +
Sbjct: 370 KSPYVQQALLQILPRLAAFNRAVFVEKYLQTCVSHLMQILRGKEKDRTVAYITIGYMAVAVQSAIEVH--LSSIMTSVKVALPSKDLTSKRKVPV-DPAVFACITLLAHAVKSEIADDVKDILEQMFYTGLSPALTVCLRELSENVPQLKSAITEGLIGILSQVLMNKAAILPYTALPTIAI---DGSLMQNG---------------DGATTVLALKTLGTFNFEEQNMLDFVQRCAD---YFIVHEQQEIRLEAVQTCTRLLK--LAVQSSESMENSKTLSDTVSHVIERLLMVAITDMDCNVRIRILRSLDETFDGKLAQPESLNSLFITLHDEIFEIRELAMVTIGRLSSINPAYVMPKLRTTMIELITDLKYSGMSRNKEQSAKMLDHLVISTPRLISSYMNPILKALVPKLH--------EPE--------------------------------------------SNP-----GVILNVLRTIGDLAEVNGGSDEMELWADDLLSILLEMLGDAGSPDKRGVALWTLGQLISATGRVVTPYHKYPVLIDILINFLKTEQRRSIRRETIRVLGLLGAMDPYKHKMNKGLIDSQKDNVLIAYSDGKVDESQ-DISTAELLVNMG-NALDEYYPAVAIAALMRILRDPTLSTRHTSVVQAVTFIFQSLGIKCVPYLAQVLPNLLDNVRTA-DNNLREFLFQQLAILVAFVKLHIISYMGDIFKLIKEFWTINTPLQNTLINLIEQIAVALGCEFRDYLAELIPQILRVLQHDNSKDRMVTRRLLQALQKFGSTLGYYLPLILPPIVKLFDSPYVPQ--QVSMVALETINNLACQLDFTDFSSRIIHPLVRVLD-AEP--------------------------ELRDQAMTTLRSLAKQLGKKYLVFVPMVQRTLNKHRIVDP----------EYEELLSKIKSCSTLA---DSYGAGESELRPSRFKNNE---PFVTDRNSNNKNLQVTTNELRTAWQVTRRVSKDDWVEWLKRLSIGLLKESPSHALRACRSLAQEYDTLLRDLFNAAFISCWTELSPDLKNELTQSLIQALQVTDMPEITQTILNLAEFMEHCDRDPIPIETKLLGTRAMACRAYAKALRYKEEEFLLREDSQ------VFESLILINNKLQQREAAEGL-LTRYRNAANELNVQGRWYEKLHNWDEALEHYERNLKTDSS----DLEARLGHMRCLEALGDWSELSNVTKHEWENFGTEAKSRAGPLAAVAAWGLQDWEAMREYVRCIPEDTQDGSYYRAVLAVHHDDFETAQRLIDETRDLLDTELTSMAGESYERAYGAMVCVQMLAELEEVIQYKLIPERREPLKTMWWKRLQGGQRLVEDWRRIIQVHSLVVKPHEDIHTWLKYASLCRKSGSLHLSHKTLVMLLGTD-PKLNPNQPLPCNQPQVTYAYTKYMAANNQLQEAY--------EQLTHFVSTYSQELSCLP--PEALKQQDQRLMARCYLRMATWQN----KLQDSIRPDAIQGALECFEKATSYDPNWYKAWHLWAYMNFKVVQAQKSAL 1774 HSP 2 Score: 632.869 bits (1631), Expect = 0.000e+0 Identity = 306/569 (53.78%), Postives = 415/569 (72.93%), Query Frame = 1
Query: 6367 LIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGE 8073
+I++R Y+ PAV+GF +ISL +LQD+LRL+ L F + + + + E + G+ I + WL VI QL+ARIDTH++ V +I LL+ +G+ HPQA+V PL +A KS S RR A KIL SM HS LV +A + +EELIR+ I W E W E LE+ASRL++ ++N MF+IL PLH ++ER +T E +F Y +L+ A RY++S DL +AW+IY ++++K S+Q+ +++LEL SP+L D LA+PGSY+P + +++I+ IK L ++TSKQ PRKL I G +G +YM+LLKGHED+RQDER MQ F L+NTL++ + T R NL+IQR +VIPLSTN+GLIGWVP+ DTL+ +IRDYR+K +V LN+EH+ ML APD++ L ++QK EVFE + ++ G DLA +LWLKS +SE WFERR N+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRMLI AMEVTGIEG +R T ++ ++R+N++SL+AVLEAF++DPLL W L D KKG +
Sbjct: 1797 MIIQR--YAVPAVQGFFRSISLIKGNSLQDTLRLLTLWFDYGNHAEVYEALLSGMKLIEINTWLQVIPQLIARIDTHRQLVGQLIHQLLMDIGKNHPQALVYPLTVASKSA-SLARRNAAFKILDSMRKHSPTLVEQAVMCSEELIRVAILWHEQWHEGLEEASRLYFGDRNVKGMFEILEPLHAMLERGPQTLKETSFSQAYGRELTEAYEWSQRYKTSAVVMDLDRAWDIYYHVFQKISRQLPQLTSLELPYVSPKLMTCKDLELAVPGSYNPGQELIRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIRDYRDKKKVPLNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNWRLLDVDKKGND 2362 HSP 3 Score: 83.1889 bits (204), Expect = 4.466e-15 Identity = 60/255 (23.53%), Postives = 123/255 (48.24%), Query Frame = 1
Query: 79 MTPIDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDF-IFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLISSPEKVES---QIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAAREGIGRRRQ----KVINDTTNQNTASSKLPMVSLGSSQFQKQISQ 819
M+ V F+ GLK+++ ++ K ++ +V EL++ S EE+ F D+ +M+ + DINE+K + M C+++ + + + S ++D+ + ND+ + + AR + + + + + +S IK++ V+ + + E +R A + +E++ T F+Q + I D + ++RE AL A VTA RE + + ++ D N + + LGSS+ QK +++
Sbjct: 1 MSTTSVVQQFVNGLKSRNRNVQNKATQDLLFYVKTELREMSQEELAQFFDEFDHHIFTMVNATDINEKKGGALAMKCLINCEGSLTARKGISPYLNRLRDLLLINDVSVMEIAARSLVKLANMPTSKGADSFDFDIKKAFEVLRGE-RQEYRRHSAVFILRELAIALPTYFYQHILTFFEVIFNAIFDPKPAIRESAGEALRAALIVTAQRESTKQSSEPQWYRICYDEANGSFNA------DLGSSKDQKGVTR 248 HSP 4 Score: 55.4546 bits (132), Expect = 1.156e-6 Identity = 24/56 (42.86%), Postives = 35/56 (62.50%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGK--EVGGNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A V+K +K KL G + ++ + V++L++QAT N NLCQ Y GWC FW
Sbjct: 2416 NSKASQVIKRVKCKLTGTDFQTEKSVNEQSQVELLIQQATNNENLCQCYIGWCPFW 2471
BLAST of Tor vs. Ensembl Fly
Match: nonC (gene:FBgn0263968 transcript:FBtr0070972) HSP 1 Score: 232.261 bits (591), Expect = 3.268e-60 Identity = 172/604 (28.48%), Postives = 289/604 (47.85%), Query Frame = 1
Query: 6457 SLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANK-----------------ILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLED-----ASRLH----------YEEKNT------TAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQI--SNVSTLELSVASPRLHDYNDWILAIPG--SYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRIN--LSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREK-----------TQVLLNREHKEML--KIAPDFEKLN-----------IIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVA-TMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTK 8061
+LRL+ L+ + H S ++EV+ GL + W ++I QL +R++ H+ +V + LL + + PQ ++ P V+ G++R + +A +L + + V L+ +EL R+ + W E W L SR+ +E KN + L L + R ET +E +F + + + +R+ +AW+ LY + + STL++ SP L +++PG ++ P+ V I S+++ + ++ +K P+K+ G +G Y FL KG ED+ DER MQF + N +M R + N SVIPL +GLI WV + A+ + ++++ + R ++ K++P K N I +V + +E+ LA LW ++ N+ W + F+R ++VMSM+GY++GLGDRH N+++ SG ++HID+ CFE T+R PEKVPFRLT+ L+ AM +TGIEG FR ++ +MRK RE+LL +LEAF++DPL+ W +D+ +
Sbjct: 1615 TLRLLRLIVK--HASGLQEVLEQGLHTTPIAPWKVIIPQLFSRLNHHEPYVRKSVCDLLCRLAKSRPQLVIFPAVV-----GANREQQDATAPPATARPTTEDACCYGYLLGELSKQAPEAVQHVKLMVKELRRVCLLWDEYWIHSLAHIYNTYVSRVSALATDFRPDDHEGKNNRFNVWRPQLLADLEALVAVTSRPPETTYERSFRKRFDAPIRLTVD-ALRHRR------YPEAWDKLKQLYHILQSNMIRGSGSTLKMQSISPVLCGIGRMRISMPGLDAHGPDGDQVYIESVESSVCVLPTKTKPKKVAFYGSNGQRYTFLFKGMEDLHLDERIMQFLSISNAIMAC-RSDAPGNGCYRAHHYSVIPLGPQSGLISWVDGVTPVFALYKKWQQRRSQVAGNAGAGAVANVPRRFTDLFYNKLSPLLAKHNMQVSDPRRQWPISVLLQVLDELSQETPNDLLARELWCQAGNAAEWRQSVRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYNVCFEKGRTLR--IPEKVPFRLTQNLVQAMGITGIEGPFRLGCEYVLKVMRKERETLLTLLEAFVYDPLVDWTTNDDAQ 2201
BLAST of Tor vs. Ensembl Fly
Match: nonC (gene:FBgn0263968 transcript:FBtr0343321) HSP 1 Score: 232.261 bits (591), Expect = 3.268e-60 Identity = 172/604 (28.48%), Postives = 289/604 (47.85%), Query Frame = 1
Query: 6457 SLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANK-----------------ILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLED-----ASRLH----------YEEKNT------TAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQI--SNVSTLELSVASPRLHDYNDWILAIPG--SYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRIN--LSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREK-----------TQVLLNREHKEML--KIAPDFEKLN-----------IIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVA-TMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTK 8061
+LRL+ L+ + H S ++EV+ GL + W ++I QL +R++ H+ +V + LL + + PQ ++ P V+ G++R + +A +L + + V L+ +EL R+ + W E W L SR+ +E KN + L L + R ET +E +F + + + +R+ +AW+ LY + + STL++ SP L +++PG ++ P+ V I S+++ + ++ +K P+K+ G +G Y FL KG ED+ DER MQF + N +M R + N SVIPL +GLI WV + A+ + ++++ + R ++ K++P K N I +V + +E+ LA LW ++ N+ W + F+R ++VMSM+GY++GLGDRH N+++ SG ++HID+ CFE T+R PEKVPFRLT+ L+ AM +TGIEG FR ++ +MRK RE+LL +LEAF++DPL+ W +D+ +
Sbjct: 1615 TLRLLRLIVK--HASGLQEVLEQGLHTTPIAPWKVIIPQLFSRLNHHEPYVRKSVCDLLCRLAKSRPQLVIFPAVV-----GANREQQDATAPPATARPTTEDACCYGYLLGELSKQAPEAVQHVKLMVKELRRVCLLWDEYWIHSLAHIYNTYVSRVSALATDFRPDDHEGKNNRFNVWRPQLLADLEALVAVTSRPPETTYERSFRKRFDAPIRLTVD-ALRHRR------YPEAWDKLKQLYHILQSNMIRGSGSTLKMQSISPVLCGIGRMRISMPGLDAHGPDGDQVYIESVESSVCVLPTKTKPKKVAFYGSNGQRYTFLFKGMEDLHLDERIMQFLSISNAIMAC-RSDAPGNGCYRAHHYSVIPLGPQSGLISWVDGVTPVFALYKKWQQRRSQVAGNAGAGAVANVPRRFTDLFYNKLSPLLAKHNMQVSDPRRQWPISVLLQVLDELSQETPNDLLARELWCQAGNAAEWRQSVRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYNVCFEKGRTLR--IPEKVPFRLTQNLVQAMGITGIEGPFRLGCEYVLKVMRKERETLLTLLEAFVYDPLVDWTTNDDAQ 2201
BLAST of Tor vs. Ensembl Fly
Match: mei-41 (gene:FBgn0004367 transcript:FBtr0074271) HSP 1 Score: 164.466 bits (415), Expect = 9.768e-40 Identity = 101/342 (29.53%), Postives = 175/342 (51.17%), Query Frame = 1
Query: 7204 VKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSANIDAINELRKALQLHV---NPNNVPTTSVQFTNVPRNHSSR 8220
+ I+ + + ++ S P+KLTI DG +Y L+K +D+R+D R M+F GL+ + + + L I+ +V+P + GL+ W+PN + ++ + + +++++ + L + P E +I +K EVF + + L + +W+E R +IR++AVMSMVGYILGLGDRH NI+ +G +H+DF F + YPE VPFRLT +I AM G+EG FR + L+++ ++L+++L F++D + T+KG T D + + LQ HV N++P ++ N N +++
Sbjct: 2179 IYISGFQESVLILRSAAKPKKLTIRCSDGKDYDVLVKPKDDLRRDARLMEFNGLVKRYLHQDAPARQRRLHIRTYAVLPFNEECGLVEWLPNLASYRSICMNLYAQRRLVMSTRQLQSLAV-PLHE--SIERKREVFTKQLVPAHPPVFQEWLRQRFATPHSWYEARNTYIRTVAVMSMVGYILGLGDRHGENILFAEGNGDAVHVDFNCLFNQGELL-PYPEVVPFRLTHNMIVAMGPLGVEGSFRKCCEITLRLLKQESKTLMSILRPFVYD------VGAQTRKGAATAKITKD--------VQRIADRLQGHVKRQQANSIPLSTEGQVNFLINEATK 2502
BLAST of Tor vs. Ensembl Zebrafish
Match: mtor (mechanistic target of rapamycin kinase [Source:ZFIN;Acc:ZDB-GENE-030131-2974]) HSP 1 Score: 822.772 bits (2124), Expect = 0.000e+0 Identity = 538/1597 (33.69%), Postives = 860/1597 (53.85%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALE---VPSQYIKQSLDFLHRCIKKEK-------PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLS--VDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPL----MGVFQQTLVDALEGSVRSILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S+ CR+L+ + + + + +++ K+P LIQ+TI + +PRLAA + QY++ ++ L C+KKEK L + + A I P +L K + IK LP KD + K+++ + ++ +++ I +++ + +KE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + +L+ + + + +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + G + + VADVL KLL+V +DP+ D+R CV S DERFDA+LAQ +L LFVA DE+FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG RNKEQ+A++L L+ AP ++ + E +L L+ +++ PD NP V + V+ I LA V G ++RK + +L P ++ M+QDS+SL KR VA+ TL + V TGYVVEPYRK+P LL +LL L+TE+ IRRE I++LG +GALDP+K K +D D V + D S +E+LVN LD+FY A A+ +L ++LRDP+ +++ + + IFK LG VQ+L QV+P + I D ++ Q+ ++ VK+H++ +M + ++ + W ++ + I L++ + + LG + K +L L + VF + +++ +L + F ++++++H+LLP ++K+ ++ LQ +K AL+ L RL E+LD +D A RI+ P+ R LD + EL + D L++L+ ++ +++ + P++ K + ++ R++ + +++K ++ E++ F+ R+ R S T V +++ +++ LQKAW A + +S DDW++WL+ S+ L KES S A+RSC +L L++ LFNA+F+SCW EL++ QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG++P IL L++INNKLQ EAASGV+ YA K + +L+ + W+E L +W AL Y +K++ N + EL LGRMRCL+ALG+W L + + V + + KMA + AAW LG +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V Q L+ELEEVIQYKLV E ++ IR+ W +RL+GCQ++++DW+++L +RSLV+ P++DM TWLK+A L +S RL ++ + L G + SK ++ L P + +++ KY W + + A +++ V+ + + + I D+ L+A+C L+LG+W + LQY Y +TE +AW AWA+ N+ + K++
Sbjct: 345 SRYCRELMEERFDQVCRWVLKYRTSKNP-LIQMTILNLLPRLAAFQPHTFTDQYLQDTMGHLLGCLKKEKERTAAFQALGLLVVAVRADIQP-------YLSKILEIIKAALPPKDFAHKRQKTMQVDATVFTCISMLSRAMGPSIQQDVKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAYQLSSPSLTNIPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIHLLSGHGHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDEVFEIRELAICTIGRLSSMNPAFVMPFLRKMLIQILTELEHSGVGRNKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKD--------PD--------------------------------------------PNP-----GVVICVLATIGELAQVSGLEMRKWMDELFPIIMDMLQDSSSLAKRQVALWTLGQQVASTGYVVEPYRKYPSLLEVLLNFLKTEQNQGIRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSADYSTSEMLVNMGNLPLDEFYPAVAIVTLMRILRDPSLSNHHTMVVQAVTFIFKSLGLKCVQFLPQVMPTFLNVI-RVCDASIREFLFQQMGMVVCFVKIHIRPYMDDIFTLIREYWTPNNPMQNTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDMSVGRNVTIK-LLMAIQLFGANLDDYLHLLLPPVVKLFDAPDV--PLQARKVALETLDRLTESLDFTDYASRIIHPIVRTLDVT---------------------------PELRNSSMDTLSSLVFQLGKKYQIFIPMVNKVM----------LKHRINHQRYDVLICRIVKGYTLAEEEEDPLIFQH--RQLRSSQSDTLVSGPVESGPMKKLH-VSTTALQKAWGAARKVSKDDWLEWLRRLSVVLLKESSSPALRSCWSLAQTYIPLARDLFNAAFLSCWSELSEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEF-----QKGASPL-ILESLISINNKLQQPEAASGVLEYAMKHF-GELEIQATWYEKLHEWEDALVAYDKKIDMNKD----DPELILGRMRCLEALGEWGQLHQQCCEEWTLVSEETQAKMARMAAAAAWGLGHWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCQMLSELEEVIQYKLVPERRDIIRETWWERLQGCQRIVEDWQRILMVRSLVINPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSK-QLDHPLPTAHPHVTYAYMKYMWKSTRKIDAFQHMQHFVQG-------MQQQAQHAIAAEDQQHKLELHKLMARCFLKLGEWQLSLQGINESTIPKVLQY-----YSHSTEHDRNWYKAWHAWAVMNFEAVLHYKHQ 1790 HSP 2 Score: 651.744 bits (1680), Expect = 0.000e+0 Identity = 320/643 (49.77%), Postives = 445/643 (69.21%), Query Frame = 1
Query: 6265 NENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSA--NIDAINELRKALQLHVNPNNVPTTSVQ 8187
N S + E++ + + + Q ++ + K L++ Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M H LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF +L PLH +MER +T E +F Y DL A++ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+ I++I SI L ++TSKQ PRKLTI+G +GH +MFLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L +++K EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++R+S++AVLEAF++DPLL W L D KG + + DS +A +++A+ + H P S+
Sbjct: 1809 NSEASNSDSEADSTEHSPVPSPGQKKVNEDLSKTLLL----YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPEVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMRSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQSIIRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMEKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYTAGQSVEAMEGIDLGETTHKKPGTTVPESIH 2446 HSP 3 Score: 77.0258 bits (188), Expect = 3.856e-13 Identity = 46/202 (22.77%), Postives = 112/202 (55.45%), Query Frame = 1
Query: 106 FLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
F++GLK+++++ + K AK+ +++V EL++ S +E TF D++ ++ S+D+NE+K ++ + ++ ++ + + S+ + ++++ ++D + + ++ + ++ + E VE ++K + + D ++EG+R A L+ +E++ A T FFQ +++ + D + ++RE AL +T RE
Sbjct: 11 FVSGLKSRNEDTRAKAAKDLQHYVTTELRELSQDEATTFYDELNHHIFELVSSSDVNEKKGGILAIVSLIGVEG-GNATRISRFANYLRNLLPSSDSVVMEMASKAMGHLSMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAVSAPTFFFQQVQPFFDNIFYAVWDSKQAIREGAVSALRACLILTTQRE 210 HSP 4 Score: 55.8398 bits (133), Expect = 1.278e-6 Identity = 22/56 (39.29%), Postives = 37/56 (66.07%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGGNLTSE--EHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ + T + V++L+KQAT + NLCQ Y GWC FW
Sbjct: 2460 NKKAIQIINRVRDKLTGRDFSHDETLDVPTQVELLIKQATSHENLCQCYIGWCPFW 2515
BLAST of Tor vs. Ensembl Zebrafish
Match: mtor (mechanistic target of rapamycin kinase [Source:ZFIN;Acc:ZDB-GENE-030131-2974]) HSP 1 Score: 822.772 bits (2124), Expect = 0.000e+0 Identity = 538/1597 (33.69%), Postives = 860/1597 (53.85%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALE---VPSQYIKQSLDFLHRCIKKEK-------PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLS--VDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPL----MGVFQQTLVDALEGSVRSILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S+ CR+L+ + + + + +++ K+P LIQ+TI + +PRLAA + QY++ ++ L C+KKEK L + + A I P +L K + IK LP KD + K+++ + ++ +++ I +++ + +KE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + +L+ + + + +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + G + + VADVL KLL+V +DP+ D+R CV S DERFDA+LAQ +L LFVA DE+FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG RNKEQ+A++L L+ AP ++ + E +L L+ +++ PD NP V + V+ I LA V G ++RK + +L P ++ M+QDS+SL KR VA+ TL + V TGYVVEPYRK+P LL +LL L+TE+ IRRE I++LG +GALDP+K K +D D V + D S +E+LVN LD+FY A A+ +L ++LRDP+ +++ + + IFK LG VQ+L QV+P + I D ++ Q+ ++ VK+H++ +M + ++ + W ++ + I L++ + + LG + K +L L + VF + +++ +L + F ++++++H+LLP ++K+ ++ LQ +K AL+ L RL E+LD +D A RI+ P+ R LD + EL + D L++L+ ++ +++ + P++ K + ++ R++ + +++K ++ E++ F+ R+ R S T V +++ +++ LQKAW A + +S DDW++WL+ S+ L KES S A+RSC +L L++ LFNA+F+SCW EL++ QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG++P IL L++INNKLQ EAASGV+ YA K + +L+ + W+E L +W AL Y +K++ N + EL LGRMRCL+ALG+W L + + V + + KMA + AAW LG +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V Q L+ELEEVIQYKLV E ++ IR+ W +RL+GCQ++++DW+++L +RSLV+ P++DM TWLK+A L +S RL ++ + L G + SK ++ L P + +++ KY W + + A +++ V+ + + + I D+ L+A+C L+LG+W + LQY Y +TE +AW AWA+ N+ + K++
Sbjct: 345 SRYCRELMEERFDQVCRWVLKYRTSKNP-LIQMTILNLLPRLAAFQPHTFTDQYLQDTMGHLLGCLKKEKERTAAFQALGLLVVAVRADIQP-------YLSKILEIIKAALPPKDFAHKRQKTMQVDATVFTCISMLSRAMGPSIQQDVKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAYQLSSPSLTNIPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIHLLSGHGHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDEVFEIRELAICTIGRLSSMNPAFVMPFLRKMLIQILTELEHSGVGRNKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKD--------PD--------------------------------------------PNP-----GVVICVLATIGELAQVSGLEMRKWMDELFPIIMDMLQDSSSLAKRQVALWTLGQQVASTGYVVEPYRKYPSLLEVLLNFLKTEQNQGIRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSADYSTSEMLVNMGNLPLDEFYPAVAIVTLMRILRDPSLSNHHTMVVQAVTFIFKSLGLKCVQFLPQVMPTFLNVI-RVCDASIREFLFQQMGMVVCFVKIHIRPYMDDIFTLIREYWTPNNPMQNTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDMSVGRNVTIK-LLMAIQLFGANLDDYLHLLLPPVVKLFDAPDV--PLQARKVALETLDRLTESLDFTDYASRIIHPIVRTLDVT---------------------------PELRNSSMDTLSSLVFQLGKKYQIFIPMVNKVM----------LKHRINHQRYDVLICRIVKGYTLAEEEEDPLIFQH--RQLRSSQSDTLVSGPVESGPMKKLH-VSTTALQKAWGAARKVSKDDWLEWLRRLSVVLLKESSSPALRSCWSLAQTYIPLARDLFNAAFLSCWSELSEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEF-----QKGASPL-ILESLISINNKLQQPEAASGVLEYAMKHF-GELEIQATWYEKLHEWEDALVAYDKKIDMNKD----DPELILGRMRCLEALGEWGQLHQQCCEEWTLVSEETQAKMARMAAAAAWGLGHWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCQMLSELEEVIQYKLVPERRDIIRETWWERLQGCQRIVEDWQRILMVRSLVINPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSK-QLDHPLPTAHPHVTYAYMKYMWKSTRKIDAFQHMQHFVQG-------MQQQAQHAIAAEDQQHKLELHKLMARCFLKLGEWQLSLQGINESTIPKVLQY-----YSHSTEHDRNWYKAWHAWAVMNFEAVLHYKHQ 1790 HSP 2 Score: 635.95 bits (1639), Expect = 0.000e+0 Identity = 316/639 (49.45%), Postives = 437/639 (68.39%), Query Frame = 1
Query: 6265 NENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSN--------RQTSRINLS----------------IQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSAN 8109
N S + E++ + + + Q ++ + K L++ Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M H LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF +L PLH +MER +T E +F Y DL A++ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+ I++I SI L ++TSKQ PRKLTI+G +GH +MFLLKGHED+RQDER MQ FGL+NTL+ ++ RQ S +++S IQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L +++K EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++R+S++AVLEAF++DPLL W L D KG + + DS +A
Sbjct: 1809 NSEASNSDSEADSTEHSPVPSPGQKKVNEDLSKTLLL----YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPEVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMRSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQSIIRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLRQVSCVHVSEHCRISDVLISLQHIIIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMEKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYTAG 2442 HSP 3 Score: 77.0258 bits (188), Expect = 4.170e-13 Identity = 46/202 (22.77%), Postives = 112/202 (55.45%), Query Frame = 1
Query: 106 FLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
F++GLK+++++ + K AK+ +++V EL++ S +E TF D++ ++ S+D+NE+K ++ + ++ ++ + + S+ + ++++ ++D + + ++ + ++ + E VE ++K + + D ++EG+R A L+ +E++ A T FFQ +++ + D + ++RE AL +T RE
Sbjct: 11 FVSGLKSRNEDTRAKAAKDLQHYVTTELRELSQDEATTFYDELNHHIFELVSSSDVNEKKGGILAIVSLIGVEG-GNATRISRFANYLRNLLPSSDSVVMEMASKAMGHLSMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAVSAPTFFFQQVQPFFDNIFYAVWDSKQAIREGAVSALRACLILTTQRE 210 HSP 4 Score: 55.8398 bits (133), Expect = 1.281e-6 Identity = 22/56 (39.29%), Postives = 37/56 (66.07%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGGNLTSE--EHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ + T + V++L+KQAT + NLCQ Y GWC FW
Sbjct: 2508 NKKAIQIINRVRDKLTGRDFSHDETLDVPTQVELLIKQATSHENLCQCYIGWCPFW 2563
BLAST of Tor vs. Ensembl Zebrafish
Match: AL844179.1 (pep chromosome:GRCz11:CHR_ALT_CTG8_1_27:46082265:46126761:-1 gene:ENSDARG00000112020.1 transcript:ENSDART00000184694.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL844179.1) HSP 1 Score: 645.58 bits (1664), Expect = 0.000e+0 Identity = 320/643 (49.77%), Postives = 445/643 (69.21%), Query Frame = 1
Query: 6265 NENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSA--NIDAINELRKALQLHVNPNNVPTTSVQ 8187
N S + E++ + + + Q ++ + K L++ Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M H LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF +L PLH +MER +T E +F Y DL A++ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+ I++I SI L ++TSKQ PRKLTI+G +GH +MFLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L +++K EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++R+S++AVLEAF++DPLL W L D KG + + DS +A +++A+ + H P S+
Sbjct: 31 NSEASNSDSEADSTEHSPVPSPGQKKVNEDLSKTLLL----YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPEVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMRSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQSIIRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMEKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYTAGQSVEAMEGIDLGETTHKKPGTTVPESIH 668
BLAST of Tor vs. Ensembl Zebrafish
Match: smg1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:ZFIN;Acc:ZDB-GENE-061013-767]) HSP 1 Score: 223.787 bits (569), Expect = 1.685e-57 Identity = 179/658 (27.20%), Postives = 287/658 (43.62%), Query Frame = 1
Query: 6457 SLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHP------------------QAMVN------PLVLAFKSG---------------------GSDRRRYNA----------NKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLE----------------------------DASRLHYEEKNTTAMFKILYPL-HI--LMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAW----EIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEML------------------KIAPDFEKLNIIQKT-----------EVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGE 8073
+LRL+ LL + H +RE + GL+ W +I QL +R++ + ++ I LL V + P QA N P +L G G + Y++ +KI+ + + +V + +L EL R+ + W E+W L+ D EK++ M +++ L H+ + ET HE ++ E YGD + N R S + +W +I +L ++ K+ S + L L SPRL + +A+PG V I S+ N + ++ +K P+KL +G DG NY +L KG ED+ DER MQF ++NT+ Q + SV PL T +GLI WV + L + + ++++ V+ ++ ++ KI+P + + + +V + + LA LW W+ + RS AVMSMVGYI+GLGDRH N+++ +G+V+HID+ CFE + PEKVPFR+T + A+ VTG+EG+FR + Q+V +MR+ RE+LL +LEAF++DPL+ W GGE
Sbjct: 1770 TLRLLRLLVK--HAGELREGLEHGLASTPTAPWRGIIPQLFSRLNHPEAYIRQSICSLLCRVAQDSPHLILYPAIVGSISLGGEAQAAGNKLPSSLPTLLGNMQGEGLCGGESETGSGPTSQESSRGEEMVMYSSEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVGELRRVTLLWDELWLGVLQQQHMHVLRRIQQLEDEVKRVQNNNTLRKDEKVAIMREKHSALMKPVVFALDHVRSITAAPAETPHE-EWFQETYGD--AIHNALERLRSPLNPANPASSWVPFKQIMLSLQQRAQKRASYL--LRLDEISPRLTAMANTEMALPGEVSATDA-VTIQSVGNTITILPTKTKPKKLYFLGSDGRNYPYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFQARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAVVQAQKAQDSFQQPQNLPMVPRPSELYYSKISPALKAVGLSLDVSRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWSVTQTYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSL-RVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQIMRRGRETLLTLLEAFVYDPLVDWT------AGGE 2412
BLAST of Tor vs. Ensembl Zebrafish
Match: smg1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:ZFIN;Acc:ZDB-GENE-061013-767]) HSP 1 Score: 223.016 bits (567), Expect = 2.606e-57 Identity = 177/658 (26.90%), Postives = 287/658 (43.62%), Query Frame = 1
Query: 6457 SLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQ-----AMVNPLVLAFK----------------------------------------SGGSDRRRYNA----------NKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLE----------------------------DASRLHYEEKNTTAMFKILYPL-HI--LMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAW----EIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEML------------------KIAPDFEKLNIIQKT-----------EVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGE 8073
+LRL+ LL + H +RE + GL+ W +I QL +R++ + ++ I LL V + P A+V + L + S G + Y++ +KI+ + + +V + +L EL R+ + W E+W L+ D EK++ M +++ L H+ + ET HE ++ E YGD + N R S + +W +I +L ++ K+ S + L L SPRL + +A+PG V I S+ N + ++ +K P+KL +G DG NY +L KG ED+ DER MQF ++NT+ Q + SV PL T +GLI WV + L + + ++++ V+ ++ ++ KI+P + + + +V + + LA LW W+ + RS AVMSMVGYI+GLGDRH N+++ +G+V+HID+ CFE + PEKVPFR+T + A+ VTG+EG+FR + Q+V +MR+ RE+LL +LEAF++DPL+ W GGE
Sbjct: 1766 TLRLLRLLVK--HAGELREGLEHGLASTPTAPWRGIIPQLFSRLNHPEAYIRQSICSLLCRVAQDSPHLILYPAIVGSISLGGEAQTAGNKLPSSLPTLLGNMQGEGLCGGESETGSGPTSQESSRGEEMVMYSSEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVGELRRVTLLWDELWLGVLQQQHMHVLRRIQQLEDEVKRVQNNNTLRKDEKVAIMREKHSALMKPVVFALDHVRSITAAPAETPHE-EWFQETYGD--AIHNALERLRSPLNPANPASSWVPFKQIMLSLQQRAQKRASYL--LRLDEISPRLTAMANTEMALPGEVSATDA-VTIQSVGNTITILPTKTKPKKLYFLGSDGRNYPYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFQARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAVVQAQKAQDSFQQPQNLPMVPRPSELYYSKISPALKAVGLSLDVSRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWSVTQTYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSL-RVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQIMRRGRETLLTLLEAFVYDPLVDWT------AGGE 2408
BLAST of Tor vs. Ensembl Xenopus
Match: tmem14a (transmembrane protein 14A [Source:Xenbase;Acc:XB-GENE-960880]) HSP 1 Score: 812.757 bits (2098), Expect = 0.000e+0 Identity = 545/1593 (34.21%), Postives = 863/1593 (54.17%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALEVPSQ-----YIKQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLS-VDQIEARNKI-IALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSVRSI--LELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S++CR+L+ K + I + +++ K+P LIQ+TI + +PRLAA PS Y+ ++ L C++KEK +++ +G I+ E +L K + +K LP KD + K+++ + ++ +++ I ++A + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + +L+ + +I I +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + G S + + VADVL KLL+V +DP+ D+R CV S DERFD +LAQ +L LFVA DE+FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG RNKEQ+A++L L+ AP ++ + E +L L+ +++ PD +V N++AT I LA V G ++RK + +L P ++ M+QDS+ L KR VA+ TL +LV TGYVVEPYRK+P LL +LL L+TE+ IRRE I++LG +GALDP+K K +D D + + D S +E+LVN LD+FY A ++ +L ++LRD + +++ + I IFK LG VQ+L QV+P + I DN ++ QL ++ V+ H++ +M ++ ++ W ++ + I L++ + + LG + K +L L+ + + D+ G +I L + F ++++++H+LLP I+K+ + S + +K AL+ + RL E+LD +D A RI+ P+ R LD S P T A D L++L+ ++ +++ + P++ K L+ + R+ ++LK +++ E++ ++ A+R L +++ P LD +++ NLQK A + +S DDW++WL+ S+ L K+S S A+RSC +L L++ LFNA+F+SCW EL + QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG +P IL L++INNKLQ EAASGV+ +A K Y +++ + W+E L +W AL Y +K+E N ++EL LGRMRCL+ALG+W L + + V++ + KMA + AAW L +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V Q L+ELEEVIQYKLV E +E IRQ W DRL+GCQ++++DW+++L ++SLV++P++DM TWLK+A L +S RL +S + L G + + + L PQ+ +++ KY W + + A ++ QK N++ + + + + D + + L+A+C L+LG+W + L+Y Y ATE +AW AWA+ N+ + K++
Sbjct: 353 SRACRELVEEKFDQICRWVLKCRSSKNP-LIQMTILNVLPRLAAFR-PSAFTADLYLPDTMSHLLSCVRKEKERTVAFQALGLISVAVRSEIRL--YLPKILEHVKAALPPKDFAHKRQKSIQVDATVFTCISMLARSMGPSIQQDIKELLEPMLSVGLSPALTAVLYDLSRHIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAQQLSSPSLTNIPEISDVGSITLALRTLGTFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIQLLSGHGHVS-QTAVQVVADVLGKLLVVGITDPDPDIRYCVLASLDERFDTHLAQAENLQALFVALNDEVFEIRELAICTIGRLSSMNPAFVMPFLRKMLIQILTELEHSGVGRNKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLRD--------PDPNP---------------------------------GVVTNVLAT----------------IGELAQVSGLEMRKWMDELFPIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPSLLEVLLNFLKTEQNQGIRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASALSLSESKANQDSADYSTSEMLVNMGNLPLDEFYPAVSVVTLMRILRDQSLSNHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLSAI-RLCDNNMREFMFQQLGMLVGFVRSHIRPYMDEIFALIKDYWTMNNPIQSTIILLIEQIVLSLGGEFKLYLPQLIPHMLRVFMHDSSVGRSVTIKLLNAIQMFGANLDDYLHLLLPPIVKLFDAPD--SPMPARKVALETVDRLTESLDFTDYASRIIHPIVRTLDMS-PDLRIT--------------------------AMDTLSSLVFQLGKKYHIFIPMVNKVLQK----------HRILHQRYEVLTCRILKGYTLADEEEDPLIYQHKAQRGNLSETAS-AP--LDAGPMKKLH-VSTTNLQKLTARR--VSKDDWLEWLRRLSVELLKDSSSPALRSCWSLAQAYNPLARDLFNAAFLSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGVVLLGERASKCRAYAKALHYKELEF-----QKGPSPA-ILESLISINNKLQQPEAASGVLEFAMKHY-GEMEIQATWYEKLHEWEDALVAYDKKIEVNKD----DSELILGRMRCLEALGEWGQLHQQCCENWTNVNEDARAKMARMAAAAAWGLEQWDSMEEYTCLIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDMLDAELTAMAGESYSRAYGAMVTCQMLSELEEVIQYKLVPERREIIRQTWWDRLQGCQRIVEDWQKILMVQSLVVSPHEDMRTWLKYASLCSKSGRLALSHKTLVMLLGVD-PALESDQPLPTAHPQVTYAYMKYMWKSTRKIEAFQHM-----QKFVNNMQLQAQHVAD----DPQHKQELQKLMARCFLKLGEWQLNLQGINECTIPCVLEY-----YSAATEHDHNWYKAWHAWAVMNFEAVLHFKHQ 1793 HSP 2 Score: 646.351 bits (1666), Expect = 0.000e+0 Identity = 306/556 (55.04%), Postives = 413/556 (74.28%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDN 8055
Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M HS LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF +L PLH +MER +T E +F Y DL A++ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLT++G +GH +MFLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L ++QK EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++++S++AVLEAF++DPLL W L D+
Sbjct: 1848 YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLDPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDS 2402 HSP 3 Score: 74.3294 bits (181), Expect = 4.628e-12 Identity = 46/202 (22.77%), Postives = 109/202 (53.96%), Query Frame = 1
Query: 106 FLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
F GL+++++E ++K AK+ +++V EL++ S EE F D++ + S+D++ERK ++ + ++ ++ + + S+ + ++++ ++D + + ++ + + + + E VE ++K + + D ++EG+R A L+ +E++ A T FFQ +++ + D + ++RE AL +T RE
Sbjct: 22 FANGLRSRNEETRIKAAKDLQHYVTTELREVSQEEATQFYDELNHFIFEFVSSSDVSERKGGILAIVSLIGVEG-GNATRISRFANYLRNLLPSSDPGVMEMASKAMGRLAMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAVSAPTFFFQQVQPFFDNIFFAVWDPKQAIREGAVAALRACLILTTQRE 221
BLAST of Tor vs. Ensembl Xenopus
Match: tmem14a (transmembrane protein 14A [Source:Xenbase;Acc:XB-GENE-960880]) HSP 1 Score: 812.372 bits (2097), Expect = 0.000e+0 Identity = 545/1593 (34.21%), Postives = 863/1593 (54.17%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALEVPSQ-----YIKQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLS-VDQIEARNKI-IALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSVRSI--LELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S++CR+L+ K + I + +++ K+P LIQ+TI + +PRLAA PS Y+ ++ L C++KEK +++ +G I+ E +L K + +K LP KD + K+++ + ++ +++ I ++A + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + +L+ + +I I +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + G S + + VADVL KLL+V +DP+ D+R CV S DERFD +LAQ +L LFVA DE+FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG RNKEQ+A++L L+ AP ++ + E +L L+ +++ PD +V N++AT I LA V G ++RK + +L P ++ M+QDS+ L KR VA+ TL +LV TGYVVEPYRK+P LL +LL L+TE+ IRRE I++LG +GALDP+K K +D D + + D S +E+LVN LD+FY A ++ +L ++LRD + +++ + I IFK LG VQ+L QV+P + I DN ++ QL ++ V+ H++ +M ++ ++ W ++ + I L++ + + LG + K +L L+ + + D+ G +I L + F ++++++H+LLP I+K+ + S + +K AL+ + RL E+LD +D A RI+ P+ R LD S P T A D L++L+ ++ +++ + P++ K L+ + R+ ++LK +++ E++ ++ A+R L +++ P LD +++ NLQK A + +S DDW++WL+ S+ L K+S S A+RSC +L L++ LFNA+F+SCW EL + QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG +P IL L++INNKLQ EAASGV+ +A K Y +++ + W+E L +W AL Y +K+E N ++EL LGRMRCL+ALG+W L + + V++ + KMA + AAW L +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V Q L+ELEEVIQYKLV E +E IRQ W DRL+GCQ++++DW+++L ++SLV++P++DM TWLK+A L +S RL +S + L G + + + L PQ+ +++ KY W + + A ++ QK N++ + + + + D + + L+A+C L+LG+W + L+Y Y ATE +AW AWA+ N+ + K++
Sbjct: 225 SRACRELVEEKFDQICRWVLKCRSSKNP-LIQMTILNVLPRLAAFR-PSAFTADLYLPDTMSHLLSCVRKEKERTVAFQALGLISVAVRSEIRL--YLPKILEHVKAALPPKDFAHKRQKSIQVDATVFTCISMLARSMGPSIQQDIKELLEPMLSVGLSPALTAVLYDLSRHIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAQQLSSPSLTNIPEISDVGSITLALRTLGTFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIQLLSGHGHVS-QTAVQVVADVLGKLLVVGITDPDPDIRYCVLASLDERFDTHLAQAENLQALFVALNDEVFEIRELAICTIGRLSSMNPAFVMPFLRKMLIQILTELEHSGVGRNKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLRD--------PDPNP---------------------------------GVVTNVLAT----------------IGELAQVSGLEMRKWMDELFPIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPSLLEVLLNFLKTEQNQGIRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASALSLSESKANQDSADYSTSEMLVNMGNLPLDEFYPAVSVVTLMRILRDQSLSNHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLSAI-RLCDNNMREFMFQQLGMLVGFVRSHIRPYMDEIFALIKDYWTMNNPIQSTIILLIEQIVLSLGGEFKLYLPQLIPHMLRVFMHDSSVGRSVTIKLLNAIQMFGANLDDYLHLLLPPIVKLFDAPD--SPMPARKVALETVDRLTESLDFTDYASRIIHPIVRTLDMS-PDLRIT--------------------------AMDTLSSLVFQLGKKYHIFIPMVNKVLQK----------HRILHQRYEVLTCRILKGYTLADEEEDPLIYQHKAQRGNLSETAS-AP--LDAGPMKKLH-VSTTNLQKLTARR--VSKDDWLEWLRRLSVELLKDSSSPALRSCWSLAQAYNPLARDLFNAAFLSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGVVLLGERASKCRAYAKALHYKELEF-----QKGPSPA-ILESLISINNKLQQPEAASGVLEFAMKHY-GEMEIQATWYEKLHEWEDALVAYDKKIEVNKD----DSELILGRMRCLEALGEWGQLHQQCCENWTNVNEDARAKMARMAAAAAWGLEQWDSMEEYTCLIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDMLDAELTAMAGESYSRAYGAMVTCQMLSELEEVIQYKLVPERREIIRQTWWDRLQGCQRIVEDWQKILMVQSLVVSPHEDMRTWLKYASLCSKSGRLALSHKTLVMLLGVD-PALESDQPLPTAHPQVTYAYMKYMWKSTRKIEAFQHM-----QKFVNNMQLQAQHVAD----DPQHKQELQKLMARCFLKLGEWQLNLQGINECTIPCVLEY-----YSAATEHDHNWYKAWHAWAVMNFEAVLHFKHQ 1665 HSP 2 Score: 645.195 bits (1663), Expect = 0.000e+0 Identity = 306/556 (55.04%), Postives = 413/556 (74.28%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDN 8055
Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M HS LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF +L PLH +MER +T E +F Y DL A++ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLT++G +GH +MFLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L ++QK EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++++S++AVLEAF++DPLL W L D+
Sbjct: 1720 YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLDPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDS 2274 HSP 3 Score: 55.0694 bits (131), Expect = 2.733e-6 Identity = 22/56 (39.29%), Postives = 35/56 (62.50%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGG--NLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ L V++L+KQAT + NLCQ Y GWC FW
Sbjct: 2321 NKKAIQIINRVRDKLTGRDFSHEETLDVATQVELLIKQATSHENLCQCYIGWCPFW 2376
BLAST of Tor vs. Ensembl Xenopus
Match: tmem14a (transmembrane protein 14A [Source:Xenbase;Acc:XB-GENE-960880]) HSP 1 Score: 811.601 bits (2095), Expect = 0.000e+0 Identity = 546/1594 (34.25%), Postives = 864/1594 (54.20%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALEVPSQ-----YIKQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLS-VDQIEARNKI-IALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSVRSI--LELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGD-FNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S++CR+L+ K + I + +++ K+P LIQ+TI + +PRLAA PS Y+ ++ L C++KEK +++ +G I+ E +L K + +K LP KD + K+++ + ++ +++ I ++A + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + +L+ + +I I +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + G S + + VADVL KLL+V +DP+ D+R CV S DERFD +LAQ +L LFVA DE+FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG RNKEQ+A++L L+ AP ++ + E +L L+ +++ PD +V N++AT I LA V G ++RK + +L P ++ M+QDS+ L KR VA+ TL +LV TGYVVEPYRK+P LL +LL L+TE+ IRRE I++LG +GALDP+K K +D D + + D S +E+LVN LD+FY A ++ +L ++LRD + +++ + I IFK LG VQ+L QV+P + I DN ++ QL ++ V+ H++ +M ++ ++ W ++ + I L++ + + LG + K +L L+ + + D+ G +I L + F ++++++H+LLP I+K+ + S + +K AL+ + RL E+LD +D A RI+ P+ R LD S P T A D L++L+ ++ +++ + P++ K L+ + R+ ++LK +++ E++ ++ A+R L +++ P LD +++ NLQK A + +S DDW++WL+ S+ L K+S S A+RSC +L L++ LFNA+F+SCW EL + QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG +P IL L++INNKLQ EAASGV+ +A K Y +++ + W+E L +W AL Y +K+E N ++EL LGRMRCL+ALG+W L + + V++ + KMA + AAW LG +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V Q L+ELEEVIQYKLV E +E IRQ W DRL+GCQ++++DW+++L ++SLV++P++DM TWLK+A L +S RL +S + L G + + + L PQ+ +++ KY W + + A ++ QK N++ + + + + D + + L+A+C L+LG+W + L+Y Y ATE +AW AWA+ N+ + K++
Sbjct: 342 SRACRELVEEKFDQICRWVLKCRSSKNP-LIQMTILNVLPRLAAFR-PSAFTADLYLPDTMSHLLSCVRKEKERTVAFQALGLISVAVRSEIRL--YLPKILEHVKAALPPKDFAHKRQKSIQVDATVFTCISMLARSMGPSIQQDIKELLEPMLSVGLSPALTAVLYDLSRHIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAQQLSSPSLTNIPEISDVGSITLALRTLGTFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIQLLSGHGHVS-QTAVQVVADVLGKLLVVGITDPDPDIRYCVLASLDERFDTHLAQAENLQALFVALNDEVFEIRELAICTIGRLSSMNPAFVMPFLRKMLIQILTELEHSGVGRNKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLRD--------PDPNP---------------------------------GVVTNVLAT----------------IGELAQVSGLEMRKWMDELFPIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPSLLEVLLNFLKTEQNQGIRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASALSLSESKANQDSADYSTSEMLVNMGNLPLDEFYPAVSVVTLMRILRDQSLSNHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLSAI-RLCDNNMREFMFQQLGMLVGFVRSHIRPYMDEIFALIKDYWTMNNPIQSTIILLIEQIVLSLGGEFKLYLPQLIPHMLRVFMHDSSVGRSVTIKLLNAIQMFGANLDDYLHLLLPPIVKLFDAPD--SPMPARKVALETVDRLTESLDFTDYASRIIHPIVRTLDMS-PDLRIT--------------------------AMDTLSSLVFQLGKKYHIFIPMVNKVLQK----------HRILHQRYEVLTCRILKGYTLADEEEDPLIYQHKAQRGNLSETAS-AP--LDAGPMKKLH-VSTTNLQKLTARR--VSKDDWLEWLRRLSVELLKDSSSPALRSCWSLAQAYNPLARDLFNAAFLSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGVVLLGERASKCRAYAKALHYKELEF-----QKGPSPA-ILESLISINNKLQQPEAASGVLEFAMKHY-GEMEIQATWYEKLHEWEDALVAYDKKIEVNKD----DSELILGRMRCLEALGEWGQLHQQCCENWTNVNEDARAKMARMAAAAAWGLGKLWDSMEEYTCLIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDMLDAELTAMAGESYSRAYGAMVTCQMLSELEEVIQYKLVPERREIIRQTWWDRLQGCQRIVEDWQKILMVQSLVVSPHEDMRTWLKYASLCSKSGRLALSHKTLVMLLGVD-PALESDQPLPTAHPQVTYAYMKYMWKSTRKIEAFQHM-----QKFVNNMQLQAQHVAD----DPQHKQELQKLMARCFLKLGEWQLNLQGINECTIPCVLEY-----YSAATEHDHNWYKAWHAWAVMNFEAVLHFKHQ 1783 HSP 2 Score: 633.254 bits (1632), Expect = 0.000e+0 Identity = 307/585 (52.48%), Postives = 414/585 (70.77%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLS--------------------------IQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKK 8064
Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M HS LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF +L PLH +MER +T E +F Y DL A++ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLT++G +GH +MFLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLS IQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L ++QK EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++++S++AVLEAF++DPLL W L D+ K
Sbjct: 1838 YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLDPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSRPRQISCVSGNIRLSTNFYCFIHICSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDSENK 2421 HSP 3 Score: 73.9442 bits (180), Expect = 5.531e-12 Identity = 46/202 (22.77%), Postives = 109/202 (53.96%), Query Frame = 1
Query: 106 FLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
F GL+++++E ++K AK+ +++V EL++ S EE F D++ + S+D++ERK ++ + ++ ++ + + S+ + ++++ ++D + + ++ + + + + E VE ++K + + D ++EG+R A L+ +E++ A T FFQ +++ + D + ++RE AL +T RE
Sbjct: 11 FANGLRSRNEETRIKAAKDLQHYVTTELREVSQEEATQFYDELNHFIFEFVSSSDVSERKGGILAIVSLIGVEG-GNATRISRFANYLRNLLPSSDPGVMEMASKAMGRLAMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAVSAPTFFFQQVQPFFDNIFFAVWDPKQAIREGAVAALRACLILTTQRE 210 HSP 4 Score: 55.0694 bits (131), Expect = 2.637e-6 Identity = 22/56 (39.29%), Postives = 35/56 (62.50%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGG--NLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ L V++L+KQAT + NLCQ Y GWC FW
Sbjct: 2479 NKKAIQIINRVRDKLTGRDFSHEETLDVATQVELLIKQATSHENLCQCYIGWCPFW 2534
BLAST of Tor vs. Ensembl Xenopus
Match: tmem14a (transmembrane protein 14A [Source:Xenbase;Acc:XB-GENE-960880]) HSP 1 Score: 810.446 bits (2092), Expect = 0.000e+0 Identity = 545/1601 (34.04%), Postives = 863/1601 (53.90%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALEVPSQ-----YIKQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLS-VDQIEARNKI-IALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQ--------QTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSVRSI--LELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S++CR+L+ K + I + +++ K+P LIQ+TI + +PRLAA PS Y+ ++ L C++KEK +++ +G I+ E +L K + +K LP KD + K+++ + ++ +++ I ++A + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + +L+ + +I I +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + G S + + VADVL KLL+V +DP+ D+R CV S DERFD +LAQ +L LFVA DE+FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG RNKEQ+A++L L+ AP ++ + E +L L+ +++ PD +V N++AT I LA V G ++RK + +L P ++ M+QDS+ L KR VA+ TL +LV TGYVVEPYRK+P LL +LL L+TE+ IRRE I++LG +GALDP+K K +D D + + D S +E+LVN LD+FY A ++ +L ++LRD + +++ + I IFK LG VQ+L QV+P + I +N + Q QL ++ V+ H++ +M ++ ++ W ++ + I L++ + + LG + K +L L+ + + D+ G +I L + F ++++++H+LLP I+K+ + S + +K AL+ + RL E+LD +D A RI+ P+ R LD S P T A D L++L+ ++ +++ + P++ K L+ + R+ ++LK +++ E++ ++ A+R L +++ P LD +++ NLQK A + +S DDW++WL+ S+ L K+S S A+RSC +L L++ LFNA+F+SCW EL + QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG +P IL L++INNKLQ EAASGV+ +A K Y +++ + W+E L +W AL Y +K+E N ++EL LGRMRCL+ALG+W L + + V++ + KMA + AAW L +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V Q L+ELEEVIQYKLV E +E IRQ W DRL+GCQ++++DW+++L ++SLV++P++DM TWLK+A L +S RL +S + L G + + + L PQ+ +++ KY W + + A ++ QK N++ + + + + D + + L+A+C L+LG+W + L+Y Y ATE +AW AWA+ N+ + K++
Sbjct: 349 SRACRELVEEKFDQICRWVLKCRSSKNP-LIQMTILNVLPRLAAFR-PSAFTADLYLPDTMSHLLSCVRKEKERTVAFQALGLISVAVRSEIRL--YLPKILEHVKAALPPKDFAHKRQKSIQVDATVFTCISMLARSMGPSIQQDIKELLEPMLSVGLSPALTAVLYDLSRHIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAQQLSSPSLTNIPEISDVGSITLALRTLGTFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIQLLSGHGHVS-QTAVQVVADVLGKLLVVGITDPDPDIRYCVLASLDERFDTHLAQAENLQALFVALNDEVFEIRELAICTIGRLSSMNPAFVMPFLRKMLIQILTELEHSGVGRNKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLRD--------PDPNP---------------------------------GVVTNVLAT----------------IGELAQVSGLEMRKWMDELFPIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPSLLEVLLNFLKTEQNQGIRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASALSLSESKANQDSADYSTSEMLVNMGNLPLDEFYPAVSVVTLMRILRDQSLSNHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLSAIRLCDNNMREKRTSLMSPQFMFQQLGMLVGFVRSHIRPYMDEIFALIKDYWTMNNPIQSTIILLIEQIVLSLGGEFKLYLPQLIPHMLRVFMHDSSVGRSVTIKLLNAIQMFGANLDDYLHLLLPPIVKLFDAPD--SPMPARKVALETVDRLTESLDFTDYASRIIHPIVRTLDMS-PDLRIT--------------------------AMDTLSSLVFQLGKKYHIFIPMVNKVLQK----------HRILHQRYEVLTCRILKGYTLADEEEDPLIYQHKAQRGNLSETAS-AP--LDAGPMKKLH-VSTTNLQKLTARR--VSKDDWLEWLRRLSVELLKDSSSPALRSCWSLAQAYNPLARDLFNAAFLSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGVVLLGERASKCRAYAKALHYKELEF-----QKGPSPA-ILESLISINNKLQQPEAASGVLEFAMKHY-GEMEIQATWYEKLHEWEDALVAYDKKIEVNKD----DSELILGRMRCLEALGEWGQLHQQCCENWTNVNEDARAKMARMAAAAAWGLEQWDSMEEYTCLIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDMLDAELTAMAGESYSRAYGAMVTCQMLSELEEVIQYKLVPERREIIRQTWWDRLQGCQRIVEDWQKILMVQSLVVSPHEDMRTWLKYASLCSKSGRLALSHKTLVMLLGVD-PALESDQPLPTAHPQVTYAYMKYMWKSTRKIEAFQHM-----QKFVNNMQLQAQHVAD----DPQHKQELQKLMARCFLKLGEWQLNLQGINECTIPCVLEY-----YSAATEHDHNWYKAWHAWAVMNFEAVLHFKHQ 1798 HSP 2 Score: 646.736 bits (1667), Expect = 0.000e+0 Identity = 306/556 (55.04%), Postives = 413/556 (74.28%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDN 8055
Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M HS LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF +L PLH +MER +T E +F Y DL A++ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLT++G +GH +MFLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L ++QK EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++++S++AVLEAF++DPLL W L D+
Sbjct: 1853 YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLDPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDS 2407 HSP 3 Score: 74.3294 bits (181), Expect = 4.478e-12 Identity = 46/202 (22.77%), Postives = 109/202 (53.96%), Query Frame = 1
Query: 106 FLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
F GL+++++E ++K AK+ +++V EL++ S EE F D++ + S+D++ERK ++ + ++ ++ + + S+ + ++++ ++D + + ++ + + + + E VE ++K + + D ++EG+R A L+ +E++ A T FFQ +++ + D + ++RE AL +T RE
Sbjct: 16 FANGLRSRNEETRIKAAKDLQHYVTTELREVSQEEATQFYDELNHFIFEFVSSSDVSERKGGILAIVSLIGVEG-GNATRISRFANYLRNLLPSSDPGVMEMASKAMGRLAMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAVSAPTFFFQQVQPFFDNIFFAVWDPKQAIREGAVAALRACLILTTQRE 215 HSP 4 Score: 55.0694 bits (131), Expect = 2.591e-6 Identity = 22/56 (39.29%), Postives = 35/56 (62.50%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGG--NLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ L V++L+KQAT + NLCQ Y GWC FW
Sbjct: 2454 NKKAIQIINRVRDKLTGRDFSHEETLDVATQVELLIKQATSHENLCQCYIGWCPFW 2509
BLAST of Tor vs. Ensembl Xenopus
Match: tmem14a (transmembrane protein 14A [Source:Xenbase;Acc:XB-GENE-960880]) HSP 1 Score: 808.52 bits (2087), Expect = 0.000e+0 Identity = 545/1594 (34.19%), Postives = 863/1594 (54.14%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALEVPSQ-----YIKQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLS-VDQIEARNKI-IALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSVRSI--LELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGD-FNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S++CR+L+ K + I + +++ K+P LIQ+TI + +PRLAA PS Y+ ++ L C++KEK +++ +G I+ E +L K + +K LP KD + K+++ + ++ +++ I ++A + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + +L+ + +I I +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + G S + + VADVL KLL+V +DP+ D+R CV S DERFD +LAQ +L LFVA DE+FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG RNKEQ+A++L L+ AP ++ + E +L L+ +++ PD +V N++AT I LA V G ++RK + +L P ++ M+QDS+ L KR VA+ TL +LV TGYVVEPYRK+P LL +LL L+TE+ IRRE I++LG +GALDP+K K +D D + + D S +E+LVN LD+FY A ++ +L ++LRD + +++ + I IFK LG VQ+L QV+P + I +N +Q L ++ V+ H++ +M ++ ++ W ++ + I L++ + + LG + K +L L+ + + D+ G +I L + F ++++++H+LLP I+K+ + S + +K AL+ + RL E+LD +D A RI+ P+ R LD S P T A D L++L+ ++ +++ + P++ K L+ + R+ ++LK +++ E++ ++ A+R L +++ P LD +++ NLQK A + +S DDW++WL+ S+ L K+S S A+RSC +L L++ LFNA+F+SCW EL + QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG +P IL L++INNKLQ EAASGV+ +A K Y +++ + W+E L +W AL Y +K+E N ++EL LGRMRCL+ALG+W L + + V++ + KMA + AAW LG +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V Q L+ELEEVIQYKLV E +E IRQ W DRL+GCQ++++DW+++L ++SLV++P++DM TWLK+A L +S RL +S + L G + + + L PQ+ +++ KY W + + A ++ QK N++ + + + + D + + L+A+C L+LG+W + L+Y Y ATE +AW AWA+ N+ + K++
Sbjct: 342 SRACRELVEEKFDQICRWVLKCRSSKNP-LIQMTILNVLPRLAAFR-PSAFTADLYLPDTMSHLLSCVRKEKERTVAFQALGLISVAVRSEIRL--YLPKILEHVKAALPPKDFAHKRQKSIQVDATVFTCISMLARSMGPSIQQDIKELLEPMLSVGLSPALTAVLYDLSRHIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAQQLSSPSLTNIPEISDVGSITLALRTLGTFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIQLLSGHGHVS-QTAVQVVADVLGKLLVVGITDPDPDIRYCVLASLDERFDTHLAQAENLQALFVALNDEVFEIRELAICTIGRLSSMNPAFVMPFLRKMLIQILTELEHSGVGRNKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLRD--------PDPNP---------------------------------GVVTNVLAT----------------IGELAQVSGLEMRKWMDELFPIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPSLLEVLLNFLKTEQNQGIRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASALSLSESKANQDSADYSTSEMLVNMGNLPLDEFYPAVSVVTLMRILRDQSLSNHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLSAIRLCDNNMREQ-----LGMLVGFVRSHIRPYMDEIFALIKDYWTMNNPIQSTIILLIEQIVLSLGGEFKLYLPQLIPHMLRVFMHDSSVGRSVTIKLLNAIQMFGANLDDYLHLLLPPIVKLFDAPD--SPMPARKVALETVDRLTESLDFTDYASRIIHPIVRTLDMS-PDLRIT--------------------------AMDTLSSLVFQLGKKYHIFIPMVNKVLQK----------HRILHQRYEVLTCRILKGYTLADEEEDPLIYQHKAQRGNLSETAS-AP--LDAGPMKKLH-VSTTNLQKLTARR--VSKDDWLEWLRRLSVELLKDSSSPALRSCWSLAQAYNPLARDLFNAAFLSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGVVLLGERASKCRAYAKALHYKELEF-----QKGPSPA-ILESLISINNKLQQPEAASGVLEFAMKHY-GEMEIQATWYEKLHEWEDALVAYDKKIEVNKD----DSELILGRMRCLEALGEWGQLHQQCCENWTNVNEDARAKMARMAAAAAWGLGKLWDSMEEYTCLIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDMLDAELTAMAGESYSRAYGAMVTCQMLSELEEVIQYKLVPERREIIRQTWWDRLQGCQRIVEDWQKILMVQSLVVSPHEDMRTWLKYASLCSKSGRLALSHKTLVMLLGVD-PALESDQPLPTAHPQVTYAYMKYMWKSTRKIEAFQHM-----QKFVNNMQLQAQHVAD----DPQHKQELQKLMARCFLKLGEWQLNLQGINECTIPCVLEY-----YSAATEHDHNWYKAWHAWAVMNFEAVLHFKHQ 1779 HSP 2 Score: 647.506 bits (1669), Expect = 0.000e+0 Identity = 307/559 (54.92%), Postives = 414/559 (74.06%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKK 8064
Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M HS LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF +L PLH +MER +T E +F Y DL A++ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLT++G +GH +MFLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L ++QK EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++++S++AVLEAF++DPLL W L D+ K
Sbjct: 1834 YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLDPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDSENK 2391 HSP 3 Score: 74.3294 bits (181), Expect = 4.590e-12 Identity = 46/202 (22.77%), Postives = 109/202 (53.96%), Query Frame = 1
Query: 106 FLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
F GL+++++E ++K AK+ +++V EL++ S EE F D++ + S+D++ERK ++ + ++ ++ + + S+ + ++++ ++D + + ++ + + + + E VE ++K + + D ++EG+R A L+ +E++ A T FFQ +++ + D + ++RE AL +T RE
Sbjct: 11 FANGLRSRNEETRIKAAKDLQHYVTTELREVSQEEATQFYDELNHFIFEFVSSSDVSERKGGILAIVSLIGVEG-GNATRISRFANYLRNLLPSSDPGVMEMASKAMGRLAMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAVSAPTFFFQQVQPFFDNIFFAVWDPKQAIREGAVAALRACLILTTQRE 210
BLAST of Tor vs. Ensembl Mouse
Match: Mtor (mechanistic target of rapamycin kinase [Source:MGI Symbol;Acc:MGI:1928394]) HSP 1 Score: 810.831 bits (2093), Expect = 0.000e+0 Identity = 535/1592 (33.61%), Postives = 857/1592 (53.83%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALE----VPSQYIKQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSV--DQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSVRSI--LELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S+ CR L+ K + + Q +++ K+ LIQ+TI + +PRLAA +QY++ +++ + C+KKEK ++ +G ++ EF+ +L + + I+ LP KD + K+++ + ++ +++ I ++A + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + L+ + + + +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + + + VADVL KLL+V +DP+ D+R CV S DERFDA+LAQ +L LFVA D++FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG R KEQ+A++L L+ AP ++ + E +L L+ +++ PD P G +++N++AT I LA V G ++RK + +L ++ M+QDS+ L KR VA+ TL +LV TGYVVEPYRK+P LL +LL L+TE+ RRE I++LG +GALDP+K K +D D V + D S +E+LVN LD+FY A ++ +L ++ RD + ++ + I IFK LG VQ+L QV+P + I D ++ QL ++ VK H++ +M +++ ++ + W + + I L++ + + LG + K +L L+ + + D +G + SI L + F ++++++H+LLP I+K+ + L +KAAL+ + RL E+LD +D A RI+ P+ R LD Q EL A D L++L+ ++ +++ + P++ K L ++ R++ + +++K +++ E++ ++ R R ++T ++++NLQKAW A + +S DDW++WL+ S+ L K+S S ++RSC L +++ LFNA+FVSCW EL + QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG P IL L++INNKLQ EAASGV+ YA K + +L+ + W+E L +W AL Y +K++ N ++ EL LGRMRCL+ALG+W L +++ V+D + KMA + AAW LG +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V L+ELEEVIQYKLV E +E IRQ W +RL+GCQ++++DW+++L +RSLV++P++DM TWLK+A L +S RL ++ + L G + S+ ++ L PQ+ +++ K W + + A +++ V+ + + + I D+ + L+A+C L+LG+W + LQY Y ATE +AW AWA+ N+ + K++
Sbjct: 359 SRCCRDLMEEKFDQVCQWVLKCRSSKNS-LIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKV--YLPRVLDIIRAALPPKDFAHKRQKTVQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAHQLASPGLTTLPEASDVASITLALRTLGSFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKD--------PD----------------------------PDPNPG---VINNVLAT----------------IGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVI-RVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSQGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEV--PLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLD---------------------------QSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVL----------VRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQH--RMLRSSQGDALASGPVETGPMKKLH-VSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEF-----QKGPTPA-ILESLISINNKLQQPEAASGVLEYAMKHF-GELEIQATWYEKLHEWEDALVAYDKKMDTNK----EDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSR-QLDHPLPTAHPQVTYAYMKNMWKSARKIDAFQHMQHFVQ-------TMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQY-----YSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQ 1807 HSP 2 Score: 654.44 bits (1687), Expect = 0.000e+0 Identity = 311/574 (54.18%), Postives = 420/574 (73.17%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSAN 8109
Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M HS LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF++L PLH +MER +T E +F Y DL A+ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLT++G +GH ++FLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L ++QK EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++++S++AVLEAF++DPLL W L D KG + + DS SA
Sbjct: 1880 YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAG 2452 HSP 3 Score: 79.337 bits (194), Expect = 8.975e-14 Identity = 49/208 (23.56%), Postives = 110/208 (52.88%), Query Frame = 1
Query: 88 IDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
+ + F +GLK++++E + K AKE +++V EL++ S EE F D++ ++ S+D NERK ++ + ++ ++ S + + + ++++ ++D + + ++ I + + + E VE ++K + + D ++EG+R A L+ +E++ T FFQ +++ + + D + ++RE AL +T RE
Sbjct: 19 VSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNS-TRIGRFANYLRNLLPSSDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQRE 224 HSP 4 Score: 55.8398 bits (133), Expect = 1.393e-6 Identity = 22/56 (39.29%), Postives = 36/56 (64.29%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGGN--LTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ + L V++L+KQAT + NLCQ Y GWC FW
Sbjct: 2494 NKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW 2549
BLAST of Tor vs. Ensembl Mouse
Match: Smg1 (SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) [Source:MGI Symbol;Acc:MGI:1919742]) HSP 1 Score: 220.705 bits (561), Expect = 1.803e-56 Identity = 180/649 (27.73%), Postives = 297/649 (45.76%), Query Frame = 1
Query: 6457 SLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKS----------------------------------GGSDRRRYNANK--------------------ILHSMEVHSARLVSEAFLLNEELIRLGISWMEMW--------------TECLEDASR-------LHYEEK-------NTTAMFKILYPL-HI--LMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAW----EIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVS-NRQ-TSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEML------------------KIAPDFEKLNI------------IQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
+LRL+ LL + H +R+ + GL W +I QL +R++ + +V I LL V + P ++ P ++ S GGS ++NK I+ + + +V + +L EL R+ + W E+W + LED + L EEK +T M I++ L H+ + ET HE ++ + YGD + N + ++ + +W EI +L ++ K+ S + L L SP L + +A+PG R V I+S+ + ++ +K P+KL +G DG +Y +L KG ED+ DER MQF ++NT+ + NRQ T R + + SV PL T +GLI WV + L + + ++++ L ++ ++ KI P + + + + K V E + + LA LW + W+ ++ RS AVMSMVGYI+GLGDRH N+++ +G+V+HID+ CFE + PEKVPFR+T+ + A+ VTG+EG+FR + Q++++MR+ RE+LL +LEAF++DPL+ W
Sbjct: 1787 TLRLLRLLVK--HAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISLSSESQASGNKYSSAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHE-KWFQDNYGD--AIDNALEKLKTPSNPAKPGSSWIPFKEIMLSLQQRAQKRASYI--LRLDEISPWLAAMTNTEIALPGEVSA-RDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFH--ARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAQDSYQTPQNPSIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKA-VLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSL-RVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDW 2423
BLAST of Tor vs. Ensembl Mouse
Match: Atr (ataxia telangiectasia and Rad3 related [Source:MGI Symbol;Acc:MGI:108028]) HSP 1 Score: 184.496 bits (467), Expect = 1.236e-45 Identity = 145/477 (30.40%), Postives = 240/477 (50.31%), Query Frame = 1
Query: 6691 KSGGSDR--RRYNANKILHSMEVHSARLVSEAFL--LNEELIRLGISWMEMWTECLEDASR--LHYEEKNT---TAMFKILYPLHILMEREIETH--HEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLEL-----SVASPRLHDYNDWILAIPGSYDPNRP-IVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVI-RDYREKTQVLLNREHKEML--KIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSH-NSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDF------GDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
K G SDR R + KI + H+ RL FL ++ + R+ S E++ +E ++ L Y ++ TA+ K YP+ + +EI T H ++ GD + + + E N D + + S ++ + + + + E+ SV P L +L ++DP + + + +++S Q P+K+++ G DG Y+ + K +D+R+D R M+F LIN + + ++ R L I+ +VIPL+ G+I WV N+ L ++ + Y+EK + +E ++ + K A EKL + Q+ + + H +L++ + +W+ R+ + RS AVMSMVGYILGLGDRH NI+ +G+ +H+DF G+ FEV PE VPFRLT ++ M G EGLFR + LMR RE L++VL+ FLHDPL++W
Sbjct: 2100 KGGRSDRLQMRNDLAKINSVLTEHTNRLAPYQFLTAFSQLISRICHSHDEVFVVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILTKAIHMKKSLEKFVGDATRLTDKLL--ELCNKSVDGSNSTLSMSTHFKMLKRLVEDPTFSEILIPLQSVMIPTLPS----VLGAHANHDPFPGHWAYLAGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKSLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKIYKEKGVYMTGKELRQCMLPKSAALSEKLKVFQELLL-------PRHPPVFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFEV-------PEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEW 2556
BLAST of Tor vs. Ensembl Mouse
Match: Atr (ataxia telangiectasia and Rad3 related [Source:MGI Symbol;Acc:MGI:108028]) HSP 1 Score: 184.496 bits (467), Expect = 1.291e-45 Identity = 145/477 (30.40%), Postives = 240/477 (50.31%), Query Frame = 1
Query: 6691 KSGGSDR--RRYNANKILHSMEVHSARLVSEAFL--LNEELIRLGISWMEMWTECLEDASR--LHYEEKNT---TAMFKILYPLHILMEREIETH--HEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLEL-----SVASPRLHDYNDWILAIPGSYDPNRP-IVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVI-RDYREKTQVLLNREHKEML--KIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSH-NSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDF------GDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
K G SDR R + KI + H+ RL FL ++ + R+ S E++ +E ++ L Y ++ TA+ K YP+ + +EI T H ++ GD + + + E N D + + S ++ + + + + E+ SV P L +L ++DP + + + +++S Q P+K+++ G DG Y+ + K +D+R+D R M+F LIN + + ++ R L I+ +VIPL+ G+I WV N+ L ++ + Y+EK + +E ++ + K A EKL + Q+ + + H +L++ + +W+ R+ + RS AVMSMVGYILGLGDRH NI+ +G+ +H+DF G+ FEV PE VPFRLT ++ M G EGLFR + LMR RE L++VL+ FLHDPL++W
Sbjct: 2106 KGGRSDRLQMRNDLAKINSVLTEHTNRLAPYQFLTAFSQLISRICHSHDEVFVVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILTKAIHMKKSLEKFVGDATRLTDKLL--ELCNKSVDGSNSTLSMSTHFKMLKRLVEDPTFSEILIPLQSVMIPTLPS----VLGAHANHDPFPGHWAYLAGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKSLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKIYKEKGVYMTGKELRQCMLPKSAALSEKLKVFQELLL-------PRHPPVFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFEV-------PEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEW 2562
BLAST of Tor vs. Ensembl Mouse
Match: Atm (ataxia telangiectasia mutated [Source:MGI Symbol;Acc:MGI:107202]) HSP 1 Score: 171.4 bits (433), Expect = 1.268e-41 Identity = 99/291 (34.02%), Postives = 158/291 (54.30%), Query Frame = 1
Query: 7201 IVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGW----VPNSDTL----NAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLH 8049
+V I S K L P+ + +G DG L+KG +D+RQD Q F + NTL+ N +T + L+I V+PLS +G++ W VP + L + R YR N+ K+M+++ +K + +K + F + I ++ + K + WFE+R + RS+A S+VGYILGLGDRH NI++ S +++HID G FE + PE VPFRL+R ++ M +TG+EG+FR + + +MR ++E+LL ++E L+DPL W ++
Sbjct: 2687 LVTIKSFKTEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEYLVNSEDGAHRRYR-PNDFSANQCQKKMMEV----QKKSFEEKYDTFMT-ICQNFEPVFRYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPT-PETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDWTMN 2970
BLAST of Tor vs. UniProt/SwissProt
Match: sp|Q9JLN9|MTOR_MOUSE (Serine/threonine-protein kinase mTOR OS=Mus musculus OX=10090 GN=Mtor PE=1 SV=2) HSP 1 Score: 810.831 bits (2093), Expect = 0.000e+0 Identity = 535/1592 (33.61%), Postives = 857/1592 (53.83%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALE----VPSQYIKQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSV--DQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSVRSI--LELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S+ CR L+ K + + Q +++ K+ LIQ+TI + +PRLAA +QY++ +++ + C+KKEK ++ +G ++ EF+ +L + + I+ LP KD + K+++ + ++ +++ I ++A + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + L+ + + + +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + + + VADVL KLL+V +DP+ D+R CV S DERFDA+LAQ +L LFVA D++FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG R KEQ+A++L L+ AP ++ + E +L L+ +++ PD P G +++N++AT I LA V G ++RK + +L ++ M+QDS+ L KR VA+ TL +LV TGYVVEPYRK+P LL +LL L+TE+ RRE I++LG +GALDP+K K +D D V + D S +E+LVN LD+FY A ++ +L ++ RD + ++ + I IFK LG VQ+L QV+P + I D ++ QL ++ VK H++ +M +++ ++ + W + + I L++ + + LG + K +L L+ + + D +G + SI L + F ++++++H+LLP I+K+ + L +KAAL+ + RL E+LD +D A RI+ P+ R LD Q EL A D L++L+ ++ +++ + P++ K L ++ R++ + +++K +++ E++ ++ R R ++T ++++NLQKAW A + +S DDW++WL+ S+ L K+S S ++RSC L +++ LFNA+FVSCW EL + QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG P IL L++INNKLQ EAASGV+ YA K + +L+ + W+E L +W AL Y +K++ N ++ EL LGRMRCL+ALG+W L +++ V+D + KMA + AAW LG +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V L+ELEEVIQYKLV E +E IRQ W +RL+GCQ++++DW+++L +RSLV++P++DM TWLK+A L +S RL ++ + L G + S+ ++ L PQ+ +++ K W + + A +++ V+ + + + I D+ + L+A+C L+LG+W + LQY Y ATE +AW AWA+ N+ + K++
Sbjct: 359 SRCCRDLMEEKFDQVCQWVLKCRSSKNS-LIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKV--YLPRVLDIIRAALPPKDFAHKRQKTVQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAHQLASPGLTTLPEASDVASITLALRTLGSFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKD--------PD----------------------------PDPNPG---VINNVLAT----------------IGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVI-RVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSQGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEV--PLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLD---------------------------QSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVL----------VRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQH--RMLRSSQGDALASGPVETGPMKKLH-VSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEF-----QKGPTPA-ILESLISINNKLQQPEAASGVLEYAMKHF-GELEIQATWYEKLHEWEDALVAYDKKMDTNK----EDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSR-QLDHPLPTAHPQVTYAYMKNMWKSARKIDAFQHMQHFVQ-------TMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQY-----YSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQ 1807 HSP 2 Score: 654.44 bits (1687), Expect = 0.000e+0 Identity = 311/574 (54.18%), Postives = 420/574 (73.17%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSAN 8109
Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M HS LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF++L PLH +MER +T E +F Y DL A+ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLT++G +GH ++FLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L ++QK EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++++S++AVLEAF++DPLL W L D KG + + DS SA
Sbjct: 1880 YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAG 2452 HSP 3 Score: 79.337 bits (194), Expect = 6.278e-13 Identity = 49/208 (23.56%), Postives = 110/208 (52.88%), Query Frame = 1
Query: 88 IDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
+ + F +GLK++++E + K AKE +++V EL++ S EE F D++ ++ S+D NERK ++ + ++ ++ S + + + ++++ ++D + + ++ I + + + E VE ++K + + D ++EG+R A L+ +E++ T FFQ +++ + + D + ++RE AL +T RE
Sbjct: 19 VSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNS-TRIGRFANYLRNLLPSSDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQRE 224 HSP 4 Score: 55.8398 bits (133), Expect = 9.744e-6 Identity = 22/56 (39.29%), Postives = 36/56 (64.29%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGGN--LTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ + L V++L+KQAT + NLCQ Y GWC FW
Sbjct: 2494 NKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW 2549
BLAST of Tor vs. UniProt/SwissProt
Match: sp|P42346|MTOR_RAT (Serine/threonine-protein kinase mTOR OS=Rattus norvegicus OX=10116 GN=Mtor PE=1 SV=1) HSP 1 Score: 808.905 bits (2088), Expect = 0.000e+0 Identity = 535/1592 (33.61%), Postives = 856/1592 (53.77%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALE----VPSQYIKQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSV--DQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSVRSI--LELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S+ CR L+ K + + Q +++ K+ LIQ+TI + +PRLAA +QY++ +++ + C+KKEK ++ +G ++ EF+ +L + + I+ LP KD + K+++ + ++ +++ I ++A + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + L+ + + + +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + + + VADVL KLL+V +DP+ D+R CV S DERFDA+LAQ +L LFVA D++FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG R KEQ+A++L L+ AP ++ + E +L L+ +++ PD P G +++N++AT I LA V G ++RK + +L ++ M+QDS+ L KR VA+ TL +LV TGYVVEPYRK+P LL +LL L+TE+ RRE I++LG +GALDP+K K +D D V + D S +E+LVN LD+FY A ++ +L ++ RD + ++ + I IFK LG VQ+L QV+P + I D ++ QL ++ VK H++ +M +++ ++ + W + + I L++ + + LG + K +L L+ + + D +G + SI L + F ++++++H+LLP I+K+ + L +KAAL+ + RL E+LD +D A RI+ P+ R LD Q EL A D L++L+ ++ +++ + P++ K L ++ R++ + +++K +++ E++ ++ R R ++T ++++NLQKAW A + +S DDW++WL+ S+ L K+S S ++RSC L +++ LFNA+FVSCW EL + QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG P IL L++INNKLQ EAASGV+ YA K + +L+ + W+E L +W AL Y +K++ N + EL LGRMRCL+ALG+W L +++ V+D + KMA + AAW LG +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V L+ELEEVIQYKLV E +E IRQ W +RL+GCQ++++DW+++L +RSLV++P++DM TWLK+A L +S RL ++ + L G + S+ ++ L PQ+ +++ K W + + A +++ V+ + + + I D+ + L+A+C L+LG+W + LQY Y ATE +AW AWA+ N+ + K++
Sbjct: 359 SRCCRDLMEEKFDQVCQWVLKCRSSKNS-LIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKV--YLPRVLDIIRAALPPKDFAHKRQKTVQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAHQLASPGLTTLPEASDVASITLALRTLGSFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKD--------PD----------------------------PDPNPG---VINNVLAT----------------IGELAQVSGLEMRKWVDELFVIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVI-RVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSQGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEV--PLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLD---------------------------QSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVL----------VRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQH--RMLRSSQGDALASGPVETGPMKKLH-VSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEF-----QKGPTPA-ILESLISINNKLQQPEAASGVLEYAMKHF-GELEIQATWYEKLHEWEDALVAYDKKMDTNKD----DPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSR-QLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQ-------TMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQY-----YSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQ 1807 HSP 2 Score: 654.055 bits (1686), Expect = 0.000e+0 Identity = 311/574 (54.18%), Postives = 420/574 (73.17%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSAN 8109
Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M HS LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF++L PLH +MER +T E +F Y DL A+ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLT++G +GH ++FLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L ++QK EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++++S++AVLEAF++DPLL W L D KG + + DS SA
Sbjct: 1880 YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNAKGNKRSRTRTDSYSAG 2452 HSP 3 Score: 78.9518 bits (193), Expect = 8.636e-13 Identity = 49/208 (23.56%), Postives = 110/208 (52.88%), Query Frame = 1
Query: 88 IDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
+ + F +GLK++++E + K AKE +++V EL++ S EE F D++ ++ S+D NERK ++ + ++ ++ S + + + ++++ ++D + + ++ I + + + E VE ++K + + D ++EG+R A L+ +E++ T FFQ +++ + + D + ++RE AL +T RE
Sbjct: 19 VSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNS-TRIGRFANYLRNLLPSSDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQRE 224 HSP 4 Score: 55.8398 bits (133), Expect = 9.663e-6 Identity = 22/56 (39.29%), Postives = 36/56 (64.29%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGGN--LTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ + L V++L+KQAT + NLCQ Y GWC FW
Sbjct: 2494 NKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW 2549
BLAST of Tor vs. UniProt/SwissProt
Match: sp|P42345|MTOR_HUMAN (Serine/threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1) HSP 1 Score: 807.749 bits (2085), Expect = 0.000e+0 Identity = 534/1592 (33.54%), Postives = 856/1592 (53.77%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALE----VPSQYIKQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSV--DQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSVRSI--LELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S+ CR L+ K + + Q +++ + K+ LIQ+TI + +PRLAA +QY++ +++ + C+KKEK ++ +G ++ EF+ +L + + I+ LP KD + K+++ + ++ +++ I ++A + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + L+ + + + +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + + + VADVL KLL+V +DP+ D+R CV S DERFDA+LAQ +L LFVA D++FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG R KEQ+A++L L+ AP ++ + E +L L+ +++ PD P G +++N++AT I LA V G ++RK + +L ++ M+QDS+ L KR VA+ TL +LV TGYVVEPYRK+P LL +LL L+TE+ RRE I++LG +GALDP+K K +D D V + D S +E+LVN LD+FY A ++ +L ++ RD + ++ + I IFK LG VQ+L QV+P + I D ++ QL ++ VK H++ +M +++ ++ + W + + I L++ + + LG + K +L L+ + + D G + SI L + F ++++++H+LLP I+K+ + L +KAAL+ + RL E+LD +D A RI+ P+ R LD Q EL A D L++L+ ++ +++ + P++ K L ++ R++ + +++K +++ E++ ++ R R ++T ++++NLQKAW A + +S DDW++WL+ S+ L K+S S ++RSC L +++ LFNA+FVSCW EL + QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG P IL L++INNKLQ EAA+GV+ YA K + +L+ + W+E L +W AL Y +K++ N + EL LGRMRCL+ALG+W L +++ V+D + KMA + AAW LG +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V L+ELEEVIQYKLV E +E IRQ W +RL+GCQ++++DW+++L +RSLV++P++DM TWLK+A L +S RL ++ + L G + S+ ++ L PQ+ +++ K W + + A +++ V+ + + + I D+ + L+A+C L+LG+W + LQY Y ATE +AW AWA+ N+ + K++
Sbjct: 359 SRCCRDLMEEKFDQVCQWVLKCRNSKNS-LIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKV--YLPRVLDIIRAALPPKDFAHKRQKAMQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKD--------PD----------------------------PDPNPG---VINNVLAT----------------IGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVI-RVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPE--APLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLD---------------------------QSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVL----------VRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQH--RMLRSGQGDALASGPVETGPMKKLH-VSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEF-----QKGPTPA-ILESLISINNKLQQPEAAAGVLEYAMKHF-GELEIQATWYEKLHEWEDALVAYDKKMDTNKD----DPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSR-QLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQ-------TMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQY-----YSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQ 1807 HSP 2 Score: 653.284 bits (1684), Expect = 0.000e+0 Identity = 311/574 (54.18%), Postives = 420/574 (73.17%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSAN 8109
Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M HS LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF++L PLH +MER +T E +F Y DL A+ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLT++G +GH ++FLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L ++QK EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++++S++AVLEAF++DPLL W L D KG + + DS SA
Sbjct: 1880 YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAG 2452 HSP 3 Score: 80.8777 bits (198), Expect = 2.293e-13 Identity = 49/208 (23.56%), Postives = 110/208 (52.88%), Query Frame = 1
Query: 88 IDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
+ + F +GLK++++E + K AKE +++V EL++ S EE F D++ ++ S+D NERK ++ + ++ ++ + + + + ++++ +ND + + ++ I + + + E VE ++K + + D ++EG+R A L+ +E++ T FFQ +++ + + D + ++RE AL +T RE
Sbjct: 19 VSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEG-GNATRIGRFANYLRNLLPSNDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQRE 224 HSP 4 Score: 55.4546 bits (132), Expect = 9.909e-6 Identity = 22/56 (39.29%), Postives = 36/56 (64.29%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGGN--LTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ + L V++L+KQAT + NLCQ Y GWC FW
Sbjct: 2494 NKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW 2549
BLAST of Tor vs. UniProt/SwissProt
Match: sp|Q9VK45|TOR_DROME (Serine/threonine-protein kinase Tor OS=Drosophila melanogaster OX=7227 GN=Tor PE=1 SV=1) HSP 1 Score: 756.133 bits (1951), Expect = 0.000e+0 Identity = 497/1562 (31.82%), Postives = 831/1562 (53.20%), Query Frame = 1
Query: 1300 KHPYLIQLTIHAIPRLAALE---VPSQYIKQSLDFLHRCIK---KEKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHL--GDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLVDALEGS---VRSILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNRI 5952
K PY+ Q + +PRLAA +Y++ + L + ++ K++ ++YIT+G++A E + L +T++K+ LP KD+++K++ P+ + +++ I L+A K+++ +K+++ M GLS L L+ +S +P+L + I L+ L + LMN + P A + +I + +L+ NG + ++AL+TL F+F++ N+ FV+ + FI +E+RLEAV+TC +LL L E + + V+ V+E+LL+V+ +D + +VR+ + +S DE FD LAQ L+ LF+ +DE+FEIR+L + +GRLS+INP+ + P LR +++ +T+L++SG SRNKEQ+A++L L+ + P + S+ +L L+P++ +P+ +NP V L V++ I +LA V G L DL+ L+ M+ D+ S DKR VA+ TL +L++ TG VV PY K+P L+ +L+ L+TE+ SIRRE I++LG +GA+DP+K K +DS D L+ +++ + D+S AELLVN LD++Y A A+ +L ++LRDPT + + + + IF+ LG V YL QVLP + A DN ++ QL I+ VKLH+ +M + +++ + W + L I L++ + + LG + + +L+ L+ + L R +L+ L +F ++ ++ ++LP I+K+ + Q+ AL+ + LA LD +D + RI+ P+ R+LD +EP EL A L +L ++ ++++V P++Q+TL + P + L+K+ S ++ D+ ES R R +N+ P + D + + ++ + L+ AW + +S DDW++WLK SI L KESPS+A+R+C +L L + LFNA+F+SCW EL+ ++ L +L L E++Q +LNL EFM HC+R +PI T L +RA+ R YAKAL YKE+EFL + + L+ INNKLQ EAA G+ L + ++L + RW+E L +W +AL Y+R L+ + S + E LG MRCL+ALGDWS L N+ ++ K++ P+ AAW L D+ M +YV IP + +G + RAV+A+ H++F A I + RD LD+ LT+MAGESY RAYG +V Q LAELEEVIQYKL+ E +E ++ W RL+G Q++++DWR+++Q+ SLV+ P++D+ TWLK+A L R+S L +S + L G++ K++ N L C PQ+ ++++KY Q Q A ++L + + ++ ++ + E+ + + L+A+C LR+ W K D++ + + + AT P +AW WA N+ ++ K+ +
Sbjct: 369 KSPYVQQALLQILPRLAAFNRAVFVEKYLQTCVSHLMQILRGKEKDRTVAYITIGYMAVAVQSAIEVH--LSSIMTSVKVALPSKDLTSKRKVPV-DPAVFACITLLAHAVKSEIADDVKDILEQMFYTGLSPALTVCLRELSENVPQLKSAITEGLIGILSQVLMNKAAILPYTALPTIAI---DGSLMQNG---------------DGATTVLALKTLGTFNFEEQNMLDFVQRCAD---YFIVHEQQEIRLEAVQTCTRLLK--LAVQSSESMENSKTLSDTVSHVIERLLMVAITDMDCNVRIRILRSLDETFDGKLAQPESLNSLFITLHDEIFEIRELAMVTIGRLSSINPAYVMPKLRTTMIELITDLKYSGMSRNKEQSAKMLDHLVISTPRLISSYMNPILKALVPKLH--------EPE--------------------------------------------SNP-----GVILNVLRTIGDLAEVNGGSDEMELWADDLLSILLEMLGDAGSPDKRGVALWTLGQLISATGRVVTPYHKYPVLIDILINFLKTEQRRSIRRETIRVLGLLGAMDPYKHKMNKGLIDSQKDNVLIAYSDGKVDESQ-DISTAELLVNMG-NALDEYYPAVAIAALMRILRDPTLSTRHTSVVQAVTFIFQSLGIKCVPYLAQVLPNLLDNVRTA-DNNLREFLFQQLAILVAFVKLHIISYMGDIFKLIKEFWTINTPLQNTLINLIEQIAVALGCEFRDYLAELIPQILRVLQHDNSKDRMVTRRLLQALQKFGSTLGYYLPLILPPIVKLFDSPYVPQ--QVSMVALETINNLACQLDFTDFSSRIIHPLVRVLD-AEP--------------------------ELRDQAMTTLRSLAKQLGKKYLVFVPMVQRTLNKHRIVDP----------EYEELLSKIKSCSTLA---DSYGAGESELRPSRFKNNE---PFVTDRNSNNKNLQVTTNELRTAWQVTRRVSKDDWVEWLKRLSIGLLKESPSHALRACRSLAQEYDTLLRDLFNAAFISCWTELSPDLKNELTQSLIQALQVTDMPEITQTILNLAEFMEHCDRDPIPIETKLLGTRAMACRAYAKALRYKEEEFLLREDSQ------VFESLILINNKLQQREAAEGL-LTRYRNAANELNVQGRWYEKLHNWDEALEHYERNLKTDSS----DLEARLGHMRCLEALGDWSELSNVTKHEWENFGTEAKSRAGPLAAVAAWGLQDWEAMREYVRCIPEDTQDGSYYRAVLAVHHDDFETAQRLIDETRDLLDTELTSMAGESYERAYGAMVCVQMLAELEEVIQYKLIPERREPLKTMWWKRLQGGQRLVEDWRRIIQVHSLVVKPHEDIHTWLKYASLCRKSGSLHLSHKTLVMLLGTD-PKLNPNQPLPCNQPQVTYAYTKYMAANNQLQEAY--------EQLTHFVSTYSQELSCLP--PEALKQQDQRLMARCYLRMATWQN----KLQDSIRPDAIQGALECFEKATSYDPNWYKAWHLWAYMNFKVVQAQKSAL 1773 HSP 2 Score: 632.484 bits (1630), Expect = 0.000e+0 Identity = 306/569 (53.78%), Postives = 415/569 (72.93%), Query Frame = 1
Query: 6367 LIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGE 8073
+I++R Y+ PAV+GF +ISL +LQD+LRL+ L F + + + + E + G+ I + WL VI QL+ARIDTH++ V +I LL+ +G+ HPQA+V PL +A KS S RR A KIL SM HS LV +A + +EELIR+ I W E W E LE+ASRL++ ++N MF+IL PLH ++ER +T E +F Y +L+ A RY++S DL +AW+IY ++++K S+Q+ +++LEL SP+L D LA+PGSY+P + +++I+ IK L ++TSKQ PRKL I G +G +YM+LLKGHED+RQDER MQ F L+NTL++ + T R NL+IQR +VIPLSTN+GLIGWVP+ DTL+ +IRDYR+K +V LN+EH+ ML APD++ L ++QK EVFE + ++ G DLA +LWLKS +SE WFERR N+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRMLI AMEVTGIEG +R T ++ ++R+N++SL+AVLEAF++DPLL W L D KKG +
Sbjct: 1796 MIIQR--YAVPAVQGFFRSISLIKGNSLQDTLRLLTLWFDYGNHAEVYEALLSGMKLIEINTWLQVIPQLIARIDTHRQLVGQLIHQLLMDIGKNHPQALVYPLTVASKSA-SLARRNAAFKILDSMRKHSPTLVEQAVMCSEELIRVAILWHEQWHEGLEEASRLYFGDRNVKGMFEILEPLHAMLERGPQTLKETSFSQAYGRELTEAYEWSQRYKTSAVVMDLDRAWDIYYHVFQKISRQLPQLTSLELPYVSPKLMTCKDLELAVPGSYNPGQELIRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIRDYRDKKKVPLNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNWRLLDVDKKGND 2361 HSP 3 Score: 83.1889 bits (204), Expect = 4.476e-14 Identity = 60/255 (23.53%), Postives = 123/255 (48.24%), Query Frame = 1
Query: 79 MTPIDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDF-IFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLISSPEKVES---QIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAAREGIGRRRQ----KVINDTTNQNTASSKLPMVSLGSSQFQKQISQ 819
M+ V F+ GLK+++ ++ K ++ +V EL++ S EE+ F D+ +M+ + DINE+K + M C+++ + + + S ++D+ + ND+ + + AR + + + + + +S IK++ V+ + + E +R A + +E++ T F+Q + I D + ++RE AL A VTA RE + + ++ D N + + LGSS+ QK +++
Sbjct: 1 MSTTSVVQQFVNGLKSRNRNVQNKATQDLLFYVKTELREMSQEELAQFFDEFDHHIFTMVNATDINEKKGGALAMKCLINCEGSLTARKGISPYLNRLRDLLLINDVSVMEIAARSLVKLANMPTSKGADSFDFDIKKAFEVLRGE-RQEYRRHSAVFILRELAIALPTYFYQHILTFFEVIFNAIFDPKPAIRESAGEALRAALIVTAQRESTKQSSEPQWYRICYDEANGSFNA------DLGSSKDQKGVTR 248
BLAST of Tor vs. UniProt/SwissProt
Match: sp|Q86C65|TOR_DICDI (Serine/threonine-protein kinase tor OS=Dictyostelium discoideum OX=44689 GN=tor PE=1 SV=1) HSP 1 Score: 649.432 bits (1674), Expect = 0.000e+0 Identity = 509/1739 (29.27%), Postives = 861/1739 (49.51%), Query Frame = 1
Query: 1204 HRSKIHLSQSCRK---LIMAKLEFIWQMLIQNFDWKHPYLIQLTIHAIPRLAAL---EVPSQYIKQSLDFLHRCIKK--EKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQ--PLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVD-QIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIK---PFLSPLMGVFQQTLVDALEGSVRSILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEI-------NSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLES-ILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRF-DQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQE---TIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISK-NNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAI----------------------------ICMSKNRIVELTRQMSVIARRWKQLQHQEVTDTRRSSLTQGFNTNSQIVNQNNGSTVMSSEVARISQP-----QLRFSLLQSQQKRGCNLVSFPSTVP---HVPESLAT 6231
H S I +S+ R +++K + I + +++ D + + + + PRLA + Y ++ L ++ E+P ++I +G IA G + +L+ + IK + + TK +Q P + I ML + + V++ +MI V GL+ L +L+ +++ +P L +I LL + + L N +EP + S ++ T G + P + N VD Q+ A +AL+TL FDF KHNL FVR +++++ E+R EA TCAQL+ +E + + ++ V +VLEKLL+V +DP+ +R V S + RFD YLAQ +L LF+A DE+FEIR+L I +GRL+ NP+ + P+LRK L+Q LTELEFSG RNKE++A++L LI S SEKL+ P ++ I+ A ++P R +NP V V+ A+ L+VV G ++ +H+ L+P +I +QD +S KR VA+ TL++L + TGYV++P+ K+P LL LL ++TE +GSIRREVIK+LG +G+LDP+K K +N++G + + K +M+ + ++ +D+Y AL +L ++LRDP+ S++ + ++ IFK L S+ +L Q++P + M + ++ QL + +VK H++ ++ + ++ + WN + L + I+L++ ++ L + K P L P M T +L L F ++++++H L + E + T Q++ A+ + RL + L+ SD A RI+ P+ R+LD +E +EL + L L+ ++ + + P++ K L + + + ++K+LK + + D A R +++ ++ D + TS +I N +L+ AW + + +DW +W++ FS+ L +ESPS A+RSC +L L K LFNA FVSCW EL + Q+ L+ +LE+ +L+ E+ Q +LNL EFM E+ LPI L + A K YAKAL+YKE EF +P + + L++INN+LQ EAA G+++YA K + +L+ E W+E L+ W AL Y++K +D+ + N T+G +RCL ALG+W L + + + ++D + +AP+ AAW L +++ M++YV ++ + EG F RA++ + H+ F A +I AR +D+ LTA+ GESY RAY +V Q+L+ELEE+I+YK +S E I+ W RL+GCQ +D W+ +L + SLV++P++++ WLKF GL R+ +RL +++ + L G + S S+ ++L P+I F++ K W+ G Q A L V+ D + + R + + L + L LGD +E+ ++ H I+S+++ ATE P +AW +WA+ N+ + I + +R ++ T + ++ +K +EV ++L QGFNT ++ + V+ +ARI P +L L+ + K + +P TV H P LA
Sbjct: 247 HGSLITVSELLRNTGDFMLSKFKDICETVLKYKDHRDKLVKKTVLALFPRLAVFCSRDFVLNYFNACMNHLLAALRNQNERPTAFIALGEIAMAVGGSIKP--YLDSIVVMIK-----QGLMTKGKQFCPEVLTCISMLASAVGQSMYPHMQVILPQMI---VSSGLTVVLTDALRDLTINLPTLIPNIQYKLLNLISQVLANKPFSEPG----APSPYRKSATPFQGGSI-PQLGQNSDVDPQMIA----LALKTLGSFDFSKHNLLEFVR---ECVVNYLDDDNIEIRREAAITCAQLMV-----GTEEPTPTRGHSAVIVGEVLEKLLVVGIADPDPSIRKTVLSSLEARFDHYLAQAENLRSLFIALNDELFEIRELAITVIGRLTIRNPAYVMPSLRKTLIQLLTELEFSGDGRNKEESARLLGHLI--------SASEKLIK---PYVEPILKA--------------------------------LLPKLRD-----------SNP-----RVASCVLAALGELSVVGGEEMVQHIDSLLPLIIDTLQDQSSTSKREVALKTLAQLASSTGYVIKPFSKYPMLLDTLLNAIKTERIGSIRREVIKVLGILGSLDPYKHK--------MNELGKRREDPKANDDKNNNMTNEVITISPS---NEDYYPTVALTALMKILRDPSLSSHHTSVIQAVMYIFKSLSLKSIPFLPQIMPPFLHA-MNTGEPLFREFLFQQLGSLVSIVKQHIRDYLVNVFALIEKYWNSN--LLIPIIKLVEEISSALNDEFKVYLPNLIPQMLNVLHTDRSPKRSPTTKVLRALEVFGTNLDDYLH--LVIPAIVKLFEQVDVTTQVRTLAIQTIGRLCKKLNFSDYASRIIHPLARVLDSTE--------------------------SELREETLNTLCALVYQLGSDYAIFIPMVGKVL----------ARREIQSTNYELLISKLLKNQQLMLTPGSGDDGGMGANRFGGDHNGHHLGE--DHNNTSTPLDIGVKKLKANEQHLKNAWETSQRSTKEDWGEWIRRFSVELLRESPSPALRSCLSLAQDYHPLVKELFNAGFVSCWTELHEQFQEELVRSLETALLSPNIPPEILQTLLNLAEFMELHEK-PLPIDIRTLGALAEKCHAYAKALHYKESEF-------SQSPSSTIEALISINNQLQQPEAAIGILIYAQKNHSVELK--EGWYEKLRRWEDALAAYEKKQKDDPNGGTIEN--TMGILRCLHALGEWERLSALSSETWKSDINDHTRATIAPLAAAAAWNLVNWDKMDEYVCAMNKDTVEGSFYRAILEVHHDNFTLAHGFIDHARTLVDTELTALLGESYNRAYKVVVRLQQLSELEEIIEYKKCVDSPERRNMIKNTWKTRLRGCQHNVDIWQSILAVHSLVISPHEELDMWLKFVGLCRKGSRLGLAQKTLTMLMGKDPSTTSQFGSVLPNTHPRITFAYIKQLWSAGAKQPAFEKLRTFVQALRDTDDLPLQGR--------------AYLKLGEWQLALGDTLSEA------SIPH-----IISSFKAATECDPNWYKAWHSWALINFEVVSHYEQNGGTPEQIGAHLLPAVHSFFKSISLGPDRSLQDT--LRLLTLWFKHGAQKEV----EAALMQGFNT----ISIDTWLHVIPQIIARIHAPVLPVRRLLHELIDTIGKEHPQALVYPLTVATKSHSPARLAA 1798 HSP 2 Score: 582.408 bits (1500), Expect = 1.053e-167 Identity = 283/568 (49.82%), Postives = 391/568 (68.84%), Query Frame = 1
Query: 6385 AYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVL----HDNTKKGGEN 8076
A+ PAV F +ISL P +LQD+LRL+ L F+ + + G + IS++ WL VI Q++ARI V ++ L+ T+G+ HPQA+V PL +A KS S R A ++ M HSA LV +A +++EL+R I W+EMW E LE+ASR ++ + N AM L PLH ++E+ ET E +F + DL A +YE + + DL QAW++Y ++R+ KQ+ +S+LEL SP+L + N+ LA+PG+Y + +++I S L+++ SKQ PRKLTIIG DG Y FLLKGHED+RQDER MQ F L+N L+ +N +T++ +LSI+R SVIPLS N+GLIGWVP+SDTL+ +I+D+R+ ++LL+ EH+ ML++ D++ L ++QK EVF+ + S+G DL +LWLKS NSE W +RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R +G ++HIDFGDCFEVA R+KYPEK+PFRLTRMLI AMEV+GIEG FR T ++N++R N+ESL+AVLEAF+HDPL+ W L +NTK N
Sbjct: 1687 AHLLPAVHSFFKSISLGPDRSLQDTLRLLTLWFKHGAQKEVEAALMQGFNTISIDTWLHVIPQIIARIHAPVLPVRRLLHELIDTIGKEHPQALVYPLTVATKSH-SPARLAAAKSLMDKMRKHSATLVDQALPVSQELVRTAILWLEMWYEGLEEASRQYFGDHNPEAMLATLAPLHQILEKGPETTSETSFLQAFGRDLQEALEWSKKYEKTRKEGDLNQAWDLYYQVFRRIYKQLPQMSSLELQYVSPKLLNSNNMELAVPGTYKASENVIRIQSFSQALSVIPSKQRPRKLTIIGSDGLEYTFLLKGHEDLRQDERVMQLFSLVNNLLSANHETAKSHLSIRRFSVIPLSPNSGLIGWVPHSDTLHTLIKDFRDSNKILLSIEHRLMLQMCSDYDNLTLLQKVEVFQYALENSNGLDLHKVLWLKSRNSEVWLDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRHTGHILHIDFGDCFEVAMHRDKYPEKIPFRLTRMLINAMEVSGIEGNFRLTCEAVMNVLRNNKESLMAVLEAFVHDPLINWRLLTPNENNTKHKATN 2253 HSP 3 Score: 64.3142 bits (155), Expect = 2.650e-8 Identity = 44/208 (21.15%), Postives = 110/208 (52.88%), Query Frame = 1
Query: 91 DYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFI-SMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
D + L LK+K +E ++K +K K++V ++ ++ ++E F++++ + I ++ S+ I E+ ++ + ++D+D+ + + ++L+ ++ ND + + ++ + + S + E VE ++ + + D + E +R A L+ KE++ A T+F+ AS ++ + + ++D + ++RE AL + + RE
Sbjct: 12 DALTKLLNDLKSKKEEDRVKASKNLKSYVISQSREMTNENFTKFMNELNNNLIFELVNSSVIPEKIGGIMAIDELIDVDYDENATKITRLANYLRIGLGFNDFTVMLMASKALGRLARSSGTLTAEFVEFEVTRALEWLSGD-RIEARRHAAVLVLKELAQNAPTLFYVHASSFVDLIWVALKDPKVAIREGAVEALRACLELISERE 218
BLAST of Tor vs. TrEMBL
Match: A0A1L7H9U7 (Serine/threonine-protein kinase TOR OS=Dugesia japonica OX=6161 PE=2 SV=1) HSP 1 Score: 4970.22 bits (12891), Expect = 0.000e+0 Identity = 2414/2870 (84.11%), Postives = 2633/2870 (91.74%), Query Frame = 1
Query: 79 MTPIDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLISSPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAAREGIGRRRQKVINDTTNQNTASSKLPMVSLGSSQFQKQISQQPVNQLRANDSGILESGKIHIEQDWSQELYSNCIAELLRTLXXXXXXXHINSRKLNQESWSHGTXXXXXXXXXXSNDEMEMNRIQLERMIGLSLDQLSSSPMPSGVLSARAICRMEWPYSKMEEHIIQHRSKIHLSQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTIHAIPRLAALEVPSQYIKQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSI-ENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLVDALEGSVRSILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNRIVELTRQMSVIARRWKQLQHQEVTDTRRSSLTQGFNTNSQIVNQNNGSTVMSSEVARISQPQLRFSLLQSQQKRGCNLVSFPSTVPHVPESLATFGQAVAVRQPDNENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSVQFTNVPRNHSSRPSSGNIPHMPDNIRIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPWFGCYNTALKMRKRATDGSIIVERNGLEGLIFSAKSPISDRPN-YDDTEDEWAGANMRAMDVMKHIKNKLEGKEVGGNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
MTP +Y++YFL GLK+KSD++KLKTAKEFKNFV N+LKDK+HEEM+ FVDK++ EFI M++SND+ +RKAVLICM CIVDLDFIFSH++F KLS +IQDMPITNDIQIS LQARLIAQFNLISSPE+VESQIKESCSV DDSKSEGQRIYAALLFKEIS YASTVFFQ+A+RVI+SLL+GIRDKQASVREVCA+ALANAFAVTAAREGIGRRRQKV N+++NQN+ +K+ M SL +SQF KQI+QQP NQ+R+++S ++ESGKIH+EQDWSQELY NCI +LLR D S S LNQE+WSHGTLLLLNELLKL NDEMEMNR+Q+E MI LSLDQ ++S MP G+ +AR +CRMEWPYS MEEHIIQHRSKIHLSQSCRK++++KL+ IW ML+QNF+WK PYLIQL IHAIPRL+AL+V S Y LDFL RCIKKEK PL+YI++GF+AHI+P EFEKN FLEKTI IK NLPGKD+S KKRQPLLEVS+YMLIGLIATGF NKVH VIK+MIGTMVEVGLS PLIYSLKMVS FIPELT DIH TLLKSLRKTLMNNSR+EPKK Q STSIS+E + LCN LLSPL A NL++DQ+EARNKIIALRTLVEFDFDKHNLSLFVRFISS+LISFI+C YKEVRLEAV+TCAQLLTPLLG+ DD S+SDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELE+SGSSRNKEQAA ILAELIDTAPGF+Q HSE+LL+VLLPRI SII AAK+QPDG+S+ E NVK H YK S S ++ IY KG+ D++DN+ +T+ + EPTAVQLAVIQAIKNLAVVCGSKLR+HL DL+PALIYMMQDSTSLDKRFVAVTTL+KLVTHTGYVVEPY+KHP+LLRLLLMMLR+EEVGSIRREVIKLLGTIGALDPFKQKKFCSE+D++NDVGLVVSMHE +EKKEVDMSQAELLVN WK LD+FY ACALQSL QLLRDPT+RS+YD+ICMVI+SIFK LGPNSVQYLKQVLPEYFRCI+EAQD+RHQ+ FL+QLC+ITDVVKLHLKQFMPQLIEILLQLW+KS LT VCI LL+SLNIGLGADIKPFLS LMGVFQQTL++A E SV ++LELLPEFEYSIEEH+HILLPSIIKIIS++N+ S L+IKKAALDCLTRLAE LDLSDSAGRIVQPVCRLLDF EP Y Q+++S Q + T LSNEQLAELIP AFDLLTTLLVKMRRRFMVLTPLIQKTLENIK FPAGTTQ M FARFNTALNKV KISY++NHEDNL++FES A RKRLENSS N D +Q+S+ Q++NS+NLQK W KMIS+DDWIQWL+NFSI+L +ESP AIRSCSNLGGCTGVLSK LFNA+FVSCWPELTDTQQD LIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKG APQN+LF+LLTINNKLQLEEAASGVVLYATKV+RD+LQNEERWHEILQDWT+ALNLYQRKLEDNDSRR+QNNELTLGRMRCLQALGDW+SLKNIGIDRF+ VDDS+K KMAPIIVNAAWALGDFNTMN+YVESIPLNNFEGPF RAVIAIQ E+FHEAS++IQKARDELDS LTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARR NRLEMSKSIMDRLYGSELSKI+KN+IL+CQFPQIIFSWSKYQWT G HQ A+ +LELLVEQKLKND++ M ER+NN+Q VDE C+K+SR+LLAKCALRLGDWYTE AKE++ H +LQYRIVSTYRIATEEAPGTKRAWQAWAMANYA ICM K R+V++ RQM +IARRWKQLQHQ+ +D R+SS+ Q FN +SQ NNGS +S+++AR+SQPQLRF+LLQSQQKRG N+VSFPSTV HVPESLATFG AVAVRQ DNENLST ++E+ND PNDL +LE QY L+KQRK LI +RE +SHPAVRGFVNAISLSP ANLQDSLRLVILLFQF H+ +IREVI DGLSKI+LENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSME HSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLH+LMEREIET HEVAFYNEYYGDLS+AKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNR IVKI+SIKNCLNLMTSKQHPRKLTIIG DGHNYMFLLKGHEDIRQDERAMQFFGL+NTL+ SNRQT+RINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKT VLLNREHKEMLKIAPDFEKLNIIQKTEVFE+GIRESDGKDLAHILWLKSHNSEAWFERR+NFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTS+QIVNLMRKNRESLLAVLEAF+HDPLLQWVLHDNTKK GENTVE +DSLSAN DA+NELRK LQL ++ +N PT SVQ TNVPRNHSSRPSSGN+P MPD++RIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPW GCYNTA+KMRKR DGSIIVERNGLEGLIFSAKSP+SDRPN YDD+EDEWAGAN+RAMDVMKHIKNKLEGKE GGNLTSEEHVDML+KQATCNYNLCQMYFGWCAFW
Sbjct: 1 MTPNEYLEYFLVGLKSKSDDVKLKTAKEFKNFVVNDLKDKTHEEMMNFVDKMFLEFIQMVDSNDVTDRKAVLICMSCIVDLDFIFSHNSFLKLSSIIQDMPITNDIQISGLQARLIAQFNLISSPERVESQIKESCSVFTDDSKSEGQRIYAALLFKEISLYASTVFFQYATRVISSLLLGIRDKQASVREVCAMALANAFAVTAAREGIGRRRQKVTNESSNQNSIVNKI-MGSLSASQFHKQINQQPANQVRSSESTVMESGKIHMEQDWSQELYCNCITDLLRNSDQSL------SSHLNQEAWSHGTLLLLNELLKLCNDEMEMNRLQIELMILLSLDQFTTSSMPLGIANARLVCRMEWPYSNMEEHIIQHRSKIHLSQSCRKIMISKLDLIWPMLLQNFEWKQPYLIQLVIHAIPRLSALDVHSLYTTNCLDFLQRCIKKEKEKPLAYISLGFLAHISPTEFEKNGFLEKTINNIKFNLPGKDVSIKKRQPLLEVSVYMLIGLIATGFLNKVHDVIKDMIGTMVEVGLSVPLIYSLKMVSRFIPELTGDIHSTLLKSLRKTLMNNSRSEPKKNQISTSISIETDISLCNNLLSPLSATNLTIDQMEARNKIIALRTLVEFDFDKHNLSLFVRFISSRLISFISCPYKEVRLEAVRTCAQLLTPLLGS-DDISSYSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEYSGSSRNKEQAAHILAELIDTAPGFIQPHSEQLLVVLLPRIHSIISAAKNQPDGQSVMEIVNVKRLHTHDGNYKRSISGSVVSIYPKGTGDVIDNIASTHNLAEPTAVQLAVIQAIKNLAVVCGSKLRRHLNDLLPALIYMMQDSTSLDKRFVAVTTLTKLVTHTGYVVEPYKKHPKLLRLLLMMLRSEEVGSIRREVIKLLGTIGALDPFKQKKFCSEIDTINDVGLVVSMHEVVEKKEVDMSQAELLVNIPWKNLDEFYVACALQSLIQLLRDPTFRSSYDKICMVIMSIFKSLGPNSVQYLKQVLPEYFRCIIEAQDSRHQEIFLTQLCVITDVVKLHLKQFMPQLIEILLQLWDKSSSLTRVCINLLRSLNIGLGADIKPFLSHLMGVFQQTLIEAAEQSVHAMLELLPEFEYSIEEHIHILLPSIIKIISRDNIASRLEIKKAALDCLTRLAERLDLSDSAGRIVQPVCRLLDFHEPVPVYPNQINTSSQ-IPTNTLSNEQLAELIPHAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKNQFPAGTTQFMCFARFNTALNKVSKISYVANHEDNLERFESIAGRKRLENSSNSTGNNTDNNQSSINQDLNSLNLQKVWTQTKMISTDDWIQWLRNFSITLIRESPCPAIRSCSNLGGCTGVLSKTLFNAAFVSCWPELTDTQQDQLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGVAPQNLLFELLTINNKLQLEEAASGVVLYATKVHRDRLQNEERWHEILQDWTRALNLYQRKLEDNDSRRIQNNELTLGRMRCLQALGDWNSLKNIGIDRFEHVDDSVKAKMAPIIVNAAWALGDFNTMNRYVESIPLNNFEGPFFRAVIAIQFEDFHEASDFIQKARDELDSYLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRCNRLEMSKSIMDRLYGSELSKITKNHILSCQFPQIIFSWSKYQWTIGHHQAAVSSLELLVEQKLKNDLLNMGERVNNLQSVDELCLKSSRLLLAKCALRLGDWYTELQAKESEGQHQDLQYRIVSTYRIATEEAPGTKRAWQAWAMANYASICMFKMRLVDINRQMHLIARRWKQLQHQDASDNRKSSINQVFNQSSQGSTSNNGSLPLSNDIARMSQPQLRFALLQSQQKRGSNMVSFPSTVLHVPESLATFGHAVAVRQFDNENLSTMSVETNDPPNDLALLETQYSNLEKQRKKLIRDREDFSHPAVRGFVNAISLSPYANLQDSLRLVILLFQFGHLQKIREVIRDGLSKINLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMESHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHLLMEREIETLHEVAFYNEYYGDLSAAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRAIVKIDSIKNCLNLMTSKQHPRKLTIIGSDGHNYMFLLKGHEDIRQDERAMQFFGLVNTLLASNRQTTRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTNVLLNREHKEMLKIAPDFEKLNIIQKTEVFEAGIRESDGKDLAHILWLKSHNSEAWFERRSNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSVQIVNLMRKNRESLLAVLEAFIHDPLLQWVLHDNTKKVGENTVEPEDSLSANQDAVNELRKQLQLPIHISNAPTPSVQITNVPRNHSSRPSSGNMPLMPDSVRIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPWLGCYNTAMKMRKRTADGSIIVERNGLEGLIFSAKSPVSDRPNTYDDSEDEWAGANVRAMDVMKHIKNKLEGKEAGGNLTSEEHVDMLIKQATCNYNLCQMYFGWCAFW 2861
BLAST of Tor vs. TrEMBL
Match: H9XVZ6 (Serine/threonine-protein kinase TOR OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 3366.63 bits (8728), Expect = 0.000e+0 Identity = 1617/1680 (96.25%), Postives = 1618/1680 (96.31%), Query Frame = 1
Query: 3799 SAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRL-------------------------------------EMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNRIVELTRQMSVIARRWKQLQHQEVTDTRRSSLTQGFNTNSQIVNQNNGSTVMSSEVARISQPQLRFSLLQSQQKRGCNLVSFPSTVPHVPESLATFGQAVAVRQPDNENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSVQFTNVPRNHSSRPSSGNIPHMPDNIRIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPWFGCYNT-----------------ALKMRKRATDGSIIVERNGLEGLIFSAKSPISDRPNYDDTEDEWAGANMRAMDVMKHIKNKLEGKEVGGNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
SAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQL+ELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILD SQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISL KESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRL EMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDAL YRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNRIVELTRQMSVIARRWKQLQHQEVTDTRRSSLTQGFNTNSQIVNQNNGSTVMSSEVARISQPQLRFSLLQSQQKRGCNLVSFPSTVPHVPESLATFGQAVAVRQPDNENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSVQFTNVPRNHSSRPSSGNIPHMPDNIRIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPWFGCYNT LKMRKRATDGSIIVERNGLEGLIFSAKSPISDRPNYDDTEDEWAGANMRAMDVMKHIKNKLEGKEVGGNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW
Sbjct: 1106 SAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLSELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDISQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLVKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLMFNLRKSGGLPKTENLVKGLKLAVLFEATKSRILLRHEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDAL-----YRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNRIVELTRQMSVIARRWKQLQHQEVTDTRRSSLTQGFNTNSQIVNQNNGSTVMSSEVARISQPQLRFSLLQSQQKRGCNLVSFPSTVPHVPESLATFGQAVAVRQPDNENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSVQFTNVPRNHSSRPSSGNIPHMPDNIRIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPWFGCYNTVSLITESDSNQRIYDILTLKMRKRATDGSIIVERNGLEGLIFSAKSPISDRPNYDDTEDEWAGANMRAMDVMKHIKNKLEGKEVGGNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 2780 HSP 2 Score: 1835.85 bits (4754), Expect = 0.000e+0 Identity = 930/952 (97.69%), Postives = 934/952 (98.11%), Query Frame = 1
Query: 1273 QMLIQNFDWKHPYLIQLTIHAIPRLAALEVPSQYIKQSLDFLHRCIKKEKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDP---ERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLVDALEGSVRSILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKIS 4119
+MLIQNFDWKHPYLIQLTIHAIPRLAALEVPSQYIKQSLDFLHRCIKKEKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKM GTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDP ERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKS ENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPELLRLLLMMLRTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLVDALEGSVRSILELLPEFEYSIEEHVHILLPSIIKIISKENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQL+ELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNK+ +IS
Sbjct: 168 RMLIQNFDWKHPYLIQLTIHAIPRLAALEVPSQYIKQSLDFLHRCIKKEKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKM-------------GTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPAFLERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSTENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPELLRLLLMMLRTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLVDALEGSVRSILELLPEFEYSIEEHVHILLPSIIKIISKENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLSELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKIYQIS 1106 HSP 3 Score: 296.975 bits (759), Expect = 1.815e-76 Identity = 165/212 (77.83%), Postives = 168/212 (79.25%), Query Frame = 1
Query: 376 MPITNDIQISALQARLIAQFNLISSPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAAREGIGRRRQKVINDTTNQNTASSKLPMVSLGSSQFQKQISQQPVNQLRANDSGILESGKIHIEQDWSQELYSNCIAELLRTLXXXXXXXH--INSRKLNQESWSH 1005
MPITNDIQISALQARLIAQFNLISSPEKVESQIKESCSVVVDDSKSEGQRIYAA SVREVCAIALANAFAVTAAREGIGRRRQKVINDTTNQNTASSKLPMVSLG+SQFQKQISQQPVNQLRANDSGILESGKIHIEQDWSQELYSNCIAELLRTLDDSSSSSH +N + W H
Sbjct: 1 MPITNDIQISALQARLIAQFNLISSPEKVESQIKESCSVVVDDSKSEGQRIYAA----------------------------------SVREVCAIALANAFAVTAAREGIGRRRQKVINDTTNQNTASSKLPMVSLGNSQFQKQISQQPVNQLRANDSGILESGKIHIEQDWSQELYSNCIAELLRTLDDSSSSSHFILNRMLIQNFDWKH 178
BLAST of Tor vs. TrEMBL
Match: A0A4E0S151 (Serine/threonine-protein kinase mTOR OS=Fasciola hepatica OX=6192 GN=D915_004858 PE=3 SV=1) HSP 1 Score: 1517.67 bits (3928), Expect = 0.000e+0 Identity = 820/1769 (46.35%), Postives = 1115/1769 (63.03%), Query Frame = 1
Query: 3727 STLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLL---DFSEPSTAYTTQ-------------LSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDN-LDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECP-STEVSQAVLNLEEFMTHCE-------RMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNN-FEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNN-ILNCQFPQIIFSWSKYQWTTGQHQMALGNLELL----VEQKLKNDIIIMTERINNIQIVDESC------------------------------VKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIIC-------MSKNRIVELTRQMSVIARRWKQLQHQEVTDTRRSSLTQGFNTN-SQIVNQNNGSTVMSSEVARISQPQLRFSLLQSQQKRGCNLVSFPSTVPHVPESLATFGQAVAVRQPDNENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYN-DWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSA---------------------NIDAINELRKALQLHVNPNNVPTTSVQFTNVPR--------------NH----------SSRPSSGN----IPHMPDNIRIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPWFGCYNTALKMRKRATDGSIIVERNGLEGLIFSAKSPISDRPNYDDTEDEWAGANMRAMDVMKHIKNKLEGKEVGGNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
++Q++++ LDCL R + +DL D AG+IV P+CRLL + Y TQ + +A T + + L P A D+LT LL++M ++F +L P++QKTL +++ P RF L +V K +Y+ D L S A + R + P+ + + T N V+L++AW + +++S DDW QWLK + +L +ESPS AIR+CS L V+ + LFNA+FVSCWPELT QQD+LI+TLE +L S +VSQ +LNLEEFM H + R+ LP++ S LA RA+KNR YAKALYYKEQEFLEE K+ S L LLTI +KLQLEEAA+GV++YAT+ DKL NEE W E L DW ALNLY+RKLED+ R N L LGRMRCL+ALG W+ L + +R++QVD++++ +MAP+ +AAWA ++ + KYV ++P N+ F+G F RAV+ I + EA +Y+ KAR+ LD+ LT MAGESY RAY DLV Q L+E EEVIQYKLV + + +R+ W RL+GCQ V++DW Q++Q+RSLV+ P +D+ T L+F GL RR+ R +++ ++ L G + + IS N I NC P ++F+++K W+TG ++ A+ L +L +E KL+ D + +N + C + R L+AKC LRLG WY+E + + TY +T P +R+ + + +A +C S + T ++ + + ++L +D+ S+ N SQ + A I P R + QS + + T+ E V P +L+ A ++P + R ++ + E ++ P+VRGFVN+ISLSP+AN+QDSLRL+ LLF+F H++ IREVI +GL+KISLENWLL+IQQLLARIDT +E+V+SII+ LLI+VG+R+PQ++V PLVLAFKSGGSDRRRYNAN+IL+SME HS RLVSEAFLLNEELIRL I+W+E+W E LEDASR+++ EK+ MF++L+PLH +M+R ET HE F E+ G+L++ + C +E + + L QAW+ Y LYR++SKQ++N++TLELSVASPRLH+Y +W LA+PGSY+P+RP+V+I+ IKNCL MTSKQHPRKLTI+G +GH YMFLLKGHED RQDER MQFFGL+NTL+++N +T R NL+IQRMS+IPLSTNTGLIGWVPNSDTL+ +IRDYREKT +LN+E++EML +APDF++LN+IQKTE+FE+G+RES G+DLA+ILWLKSH+SEAWFERRTNF+RS+A MSMVGYILGLGDRHPSNIML R++GKV+HIDFGDCFEVA MREK+PEKVPFRLTRM+I AMEVTGI+G++R T +++L+R +RESLLAVLEAF++DPLLQWVL +N K + DD + + + A HV+PN+ VQ T R NH SS+P SG+ P+ P R+FT+ N+PDS +LR+P+ +N WRHHLCNGPWFG Y T+ +RK+ G I+VER GL G IFSAK P + + D N RA VM+ I+ KL G E + VD L+++AT N NLCQMY GWCAFW
Sbjct: 201 GSVQLRRSCLDCLARFTDRIDLDDLAGQIVHPICRLLMKLEACHQQFQYLTQHHHHMGTGSSSSSSGTKSAALAGTEACVKAINTLHPAAVDVLTGLLLRMGQKFKLLLPVVQKTLNSLRLRTP----------RFYMVLGRVEKGAYLPTTSDQVLADIVSVAAQNRNLRAVAQEPDPVPSPGLLRT---NGVSLERAWGSSRIVSRDDWDQWLKTLTTALLRESPSPAIRACSQLTAIAPVIGRTLFNAAFVSCWPELTPPQQDSLISTLEWVLRVADQSPDVSQTILNLEEFMAHVDKYAASSPRVPLPLSLSVLADRAMKNRAYAKALYYKEQEFLEELEKRSSPSPTTLSCLLTIYSKLQLEEAAAGVLIYATRNPNDKLVNEEVWREKLHDWKHALNLYERKLEDD--RIKDKNALILGRMRCLRALGQWAPLNAMAWERWEQVDENMRAEMAPLACSAAWATNSWDQVEKYVSALPANDSFDGAFYRAVLKIHSGSYSEACDYVAKARNVLDADLTTMAGESYDRAYADLVGTQLLSEAEEVIQYKLVPDRRPILREVWRSRLRGCQAVVEDWGQIIQLRSLVMEPQEDLKTRLRFVGLCRRNGRFILARQLLQNLLGQDPASISPNEPIPNCD-PAVVFAYTKLLWSTGAYEEAVTRLCVLKTNVLEPKLRVD---HSSSLNLQRQSASGCHLWSSIGTVSSNDALDAWDPRSASSQTALEFQRYRTLMAKCCLRLGSWYSELYTRSPPGCGSGVGS---DTYYSSTS-GPVPRRS----SRSTWAPMCGLDPGLSTSYQLLRNNTTRLQLSGNQTRRLP----SDSSGSNPADNVGVNVSQAWEDGQAFVIQCYRAATIHAPDNR-AAWQSWAMANYAVFNHLDTIKARIERAEMELNKVGSTSPSPHSLNAAGTGGGNTPPAAQPIAELVRAKTDLQRCM----ELHAAPSVRGFVNSISLSPSANMQDSLRLINLLFKFGHLAEIREVIREGLTKISLENWLLIIQQLLARIDTPREYVASIIIDLLISVGQRYPQSLVYPLVLAFKSGGSDRRRYNANRILYSMEEHSPRLVSEAFLLNEELIRLSITWVELWFESLEDASRVYFGEKDIGKMFRLLHPLHQMMDRGHETIHEATFLQEHGGELANCRVCCETFERTGARIVLQQAWDRYYTLYRRFSKQVNNMTTLELSVASPRLHEYGQNWQLAVPGSYEPHRPLVRISGIKNCLTFMTSKQHPRKLTILGSNGHQYMFLLKGHEDTRQDERVMQFFGLVNTLLMNNAETLRRNLTIQRMSIIPLSTNTGLIGWVPNSDTLHGLIRDYREKTGTMLNKENREMLFLAPDFDRLNVIQKTEIFEAGLRESSGRDLANILWLKSHSSEAWFERRTNFVRSMATMSMVGYILGLGDRHPSNIMLSRETGKVVHIDFGDCFEVAMMREKFPEKVPFRLTRMIIAAMEVTGIDGVYRQTCEMVLSLVRTHRESLLAVLEAFIYDPLLQWVLLENRKDFTHLDNKVDDPAAGGNATTAAAVTAVAAAPGPGQNGVAPVVNGIPAPTAHVDPNHRLAQGVQTTTARRPVDRTGGLVGVHTGNHLQPNHYEHQTSSQPHSGHASARCPNSPR--RVFTNPNHPDSLSLRDPHKINPWRHHLCNGPWFGRYETSKLLRKQTESGHIVVERKGLSGFIFSAKPPSEEEASSDSEAYPVTWGNTRARTVMEKIRQKLTGTEREHPMNVSTQVDYLIREATSNQNLCQMYIGWCAFW 1931 HSP 2 Score: 67.3958 bits (163), Expect = 7.823e-7 Identity = 33/89 (37.08%), Postives = 58/89 (65.17%), Query Frame = 1
Query: 3415 VVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTL-VDALEGSVRSILELLPEFEYSIEEHVH 3678
VV+LH K+F ++I++L+ W + + CI +L S+ LGA+ +P+L+ L+ V +TL + E ++ ++LE+LPEF Y++E H H
Sbjct: 3 VVRLHTKEFAHEVIDLLIAHWWIAPNVQNACITVLSSMVAALGAEFRPYLTRLIPVILRTLHHETSETNLIALLEVLPEFGYTLESHAH 91
BLAST of Tor vs. TrEMBL
Match: A0A3R7FPN5 (Serine/threonine-protein kinase mTOR (Fragment) OS=Clonorchis sinensis OX=79923 GN=Mtor PE=3 SV=1) HSP 1 Score: 1488.78 bits (3853), Expect = 0.000e+0 Identity = 820/1770 (46.33%), Postives = 1100/1770 (62.15%), Query Frame = 1
Query: 3733 LQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLL--------------------DFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDN-LDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESIL-NECPSTEVSQAVLNLEEFMTHCE-------RMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLN-NFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLV----EQKLKNDIIIMTERINNIQIVDESCVKNS-----------------RILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNRIVELTRQMSVIARRWKQLQHQEVTDTRRS-SLTQGFNTNSQIVNQNNGSTVMSSEVARISQPQLRFSLLQSQQKRGCNLVSFPSTVPHVPESLATFGQAV----AVRQ-----------------------PDNENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDY-NDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDD--SLSANIDA---INELRKALQLHVNPN-NVPTTSVQFTNVP-------RNHSS----RPSS------------------------GNIPHMPDN-----IRIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPWFGCYNTALKMRKRATDGSIIVERNGLEGLIFSAKSPISDRPNYDDTE-DEWAGANMRAMDVMKHIKNKLEGKEVGGNLTSEEHVDMLVKQATCNYNLCQMYFG 8661
LQ++ A L+CL RL + +DL D + +IV P+CRLL S PS+ T +S +Q L + + L P A D+LT LL++M ++F +L PL++K L+ + + RF T L +V K +Y+ D L S A + R + + P D S + NL++AW + +IS +DW QWL + +L +ESP+ AIR+CSNL + + LFNA+FVSCWPELT QQD LI+ LE +L + S EVSQA+LNLEEFM H + R+ LP++ LA RA+KNR YAKALYYKEQEFLEE K S Q L LLTI +KLQL+EAA+GV++YAT+ DKL NEE W E LQDW ALNLY+ KL+D R LGRMRCL+ALG W LK + +D VD+S++ +MAP+ +AAWA +++ + +Y ++P + NF G F R+V+ I F A YI KARD LD+ LT M GESY RAY DLV Q L+E EEVIQYKLV E + +R+AW RL GCQ V++DW Q+LQ+RSLVL P D+ TWL+FAGL RRS R +++ ++ L + + + + P +F+++K W+TG H+ A+ L +L+ E L ++ + ++ + ++D + V +S R L+AKC LRLG WY+E A+ + + S ++ +PGT + A A +L+R + R + Q + R +++ N GSTVM +S PQ + +G ++ + H P + A + AV Q P + +LS T + S +L L +K L E ++ P+VRGFVN+ISLSP+ANLQDSLRL+ LLF+F H+ IREVI +GL+KI L NWLLV+QQLLARIDT +E+V+SIIV +LI VG+ +PQ++V LVLAFKSGGSDRRRYNAN+IL+SME HS RLVSEAFLLNEELIRL I+W+EMW+E LEDASR+++ EK+ MF+ILYPLH++M+R ET HE AF E+ DL + + C YE ++ K L QAWE Y LYR+++KQ++N+ TLEL VASPRLH+Y DW LA+PGSY+PNRP+V+I IKNCL LMTSKQHPRKLT++G DGH Y+FLLKGHED RQDER MQFFGL+NTL+++N +T R NL+IQRMSVIPLSTNTGLIGWVPNSDTL+++IRDYREKTQ +LN+E++EM+++A DF++LN+IQKTE+FE+G+R+S G+DLA+ILWLKSH+SEAWFERRTNF+RS+A MSMVGYILGLGDRHPSNIML R++GKV+HIDFGDCFEVA MREK+PEKVPFRLTRM+I AMEV GI+G++R T +++LMR +RESLLAVLEAF+HDPLLQWV+ +N K + + DD S++ I NE+ Q +N N+ + Q P R H + RP+ ++PH P R+FT+ N+PDS +LR+P+ +N WRHHLCNGPWFGCY TA ++RK+ T+ +VER GL+G IFSAK P+++ Y++TE N +A V+ I+ KL G E + VD L+++AT N NLCQMY G
Sbjct: 130 LQLRVACLECLARLTDRMDLDDFSCQIVHPICRLLLTLEGYHQQLQYLNQHPHHLPSSAPSSTMKTAVSHGIQ------LCSNAINALHPAAVDVLTGLLLRMGQKFKLLLPLVRKMLDTLH----------LRPTRFYTVLGRVEKGAYLPMTSDQYLTGITSLATQTRAQRTVQREP---DASAVIKVLDTKGANLERAWRSSTLISREDWDQWLMTLTTALLRESPNPAIRACSNLIAINNTIGRTLFNAAFVSCWPELTAPQQDALISKLEEVLLSSDQSPEVSQAILNLEEFMAHVDKYSSTSTRVPLPLSLHLLADRAMKNRAYAKALYYKEQEFLEEVKKLSSPSQETLSCLLTIYSKLQLDEAATGVLIYATRQPNDKLVNEEAWRERLQDWKCALNLYENKLKDE--RIKDKTPHMLGRMRCLRALGQWVPLKTMVSKNWDLVDESVRRQMAPMACSAAWAADEWDQVERYASALPTDQNFYGAFYRSVLDIHSGRFDRACHYIAKARDVLDADLTTMTGESYDRAYADLVGTQLLSEAEEVIQYKLVPERRSVLREAWCARLLGCQSVVEDWGQVLQLRSLVLKPQDDLKTWLRFAGLCRRSGRFTLARELLQNLLSHDPAHSPQTEPIPNADPATVFAYTKLLWSTGAHEEAVTRLYVLITRVLEPMLSSEAVTLSNPRSFASVLDANEVLDSFDPKTTAAQAVLERQELRALMAKCCLRLGSWYSELYARCPPGTYSSDG----SASTVSQSYSPGTGGLQASVATA------------TKLSRSQTSTIRGPETPSAQPLRAARSGIQISESDQARKTPGNTATGSTVMDG--GGVSVPQ------TWDEHQGFVILCYDVATNHAPGNRAAWHSWAMANYAVFQHLDTLKARIERAEMDLNKAGSTSPGSHSLSKPTSPAVTSVGNLSPSSQGIVDLWHAKKKLQFCMELHAAPSVRGFVNSISLSPSANLQDSLRLIDLLFKFGHLVEIREVIREGLAKIRLSNWLLVVQQLLARIDTPREYVASIIVDMLIAVGKSYPQSLVYSLVLAFKSGGSDRRRYNANRILYSMEEHSPRLVSEAFLLNEELIRLSITWVEMWSEALEDASRVYFGEKDIMKMFRILYPLHLMMDRGHETAHESAFLQEHGNDLRNCRFCCETYERNSSKIVLQQAWEGYYTLYRQFTKQMNNMPTLELVVASPRLHEYRKDWELAVPGSYEPNRPLVRIAGIKNCLTLMTSKQHPRKLTVLGSDGHQYVFLLKGHEDTRQDERVMQFFGLVNTLLMNNSETLRRNLTIQRMSVIPLSTNTGLIGWVPNSDTLHSLIRDYREKTQTILNKENREMIRLARDFDRLNVIQKTEIFEAGLRDSSGRDLANILWLKSHSSEAWFERRTNFVRSMATMSMVGYILGLGDRHPSNIMLSRETGKVVHIDFGDCFEVAMMREKFPEKVPFRLTRMIIAAMEVIGIDGVYRQTCEMVMSLMRNDRESLLAVLEAFIHDPLLQWVILENRKDFTQMDNKLDDGASMAGTIGGQPTTNEVMAPGQPMMNGGANMMGANQQQKGHPKQPEHPYRQHQTTTARRPADRTGGLVPPNAQHHGYEYQAYHQQQNHLPHPPTRRSTSPRRVFTNPNHPDSVSLRDPHRINHWRHHLCNGPWFGCYETARRLRKQ-TEAGQVVERQGLQGFIFSAK-PLNEEDAYNETEASPITLENAKARAVVDKIRQKLNGTEREQPMNVPNQVDYLIREATSNQNLCQMYIG 1852
BLAST of Tor vs. TrEMBL
Match: A0A3Q0KKH1 (Ataxia telangiectasia mutated (Atm)-related OS=Schistosoma mansoni OX=6183 PE=3 SV=1) HSP 1 Score: 1403.65 bits (3632), Expect = 0.000e+0 Identity = 756/1563 (48.37%), Postives = 1013/1563 (64.81%), Query Frame = 1
Query: 3727 STLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEP-----------STAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLD-QFESFARRKRLENSSTYVPNILDTSQTSMTQE---INSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECP--STEVSQAVLNLEEFMTHCE-------RMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNN-FEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELL----------------------VEQKLKNDIIIMTERINN-------IQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALH----HNLQYRIVSTYRIATEEAPGTKRAWQAWAMA----NYAII------CMSKNRIVELTRQMSVIARRWKQLQHQEVTDTRRSSLTQGFNTNSQIVNQNNGST-------------VMSSEVARISQPQLRFSL-------------------------LQSQQKRGCNLVSFPSTVPHVPESLATFGQAVAVRQPDNENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYN-DWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDD 8094
++ ++KA L+CL R + +DL D AG+I+ P+CRLL E ++ S+SL A N NE L PA D+LT LL +M ++F PL+QK L ++ H P RFNT L +V K +Y+ D +F S + R R + + +D S+T T + IN+ NL++AW + +M+S DDW QWLK +++L +ESPS AIR+CS L T + + LFNA+F+SCWPEL QQD+LI TLE +L P S EVSQ +LNLEEFM H + R+ LP+ LA RALKNR YAKALYYKEQEFL E+ K+ L LLTI +KL LEEAA+GV+LYAT+ +DKL NEE W E L DW ALNLY+RKLED+ R + L LGRMRCL+ALG W+ L N+ +R++ V+D ++ MAP+ +AAWAL ++ + +Y E++ +N F+G F RAV+ I E++ +A ++I KARD LDS LTAMA ESY RAY DLV Q L+E EEVIQYKL+ E + +R+AW RL GC VI+DW Q++Q+RSLVL P +D +WL+FAGL RRS R +S+ +++ L G + + I + + P I+F ++K W G H+ A+ L +L V Q L +++ E ++ IQI++E K R LLAKC L+LG WY+E + H H+L Y S + A+ A A ++ N +I MS+ + L+ S I ++ ++ + RR++ G + +VN+N ++ + + A + P R + L+ + G + S ++ + S G V Q + NL I SN SP + E D QR E ++ P+V+GFVN+ISLSPTANLQDSLRL+ LLF+F H++ IREVI +GL+KI L+NWLLVIQQLLARIDT +E+V++II+ LLI+VG+R+PQ+MV PLVLAFKSGGSDRRRYNAN+IL+SME ++RL+SEAFLLNEELIRL I+W+EMW+E LEDASR+++ EK+ MF++L+PLH +M+R ET HE F E DL+ ++ C RYE + + DL +AWE Y LYR+++KQ++N++TLEL+V+SPRLH+Y DW LA+PGSY+P+RP+V+I SIKNCL +TSKQ PRKLTI G +GH Y+FLLKGHED RQDER MQFFGL+NTL+++N +T R NL+IQRMSVIPLST TGLIGWVPNSDT + +IRDYREK V+LN+E++EML++APDF++LN+IQKTE+FE+G+RES G+DLA+ILWLKSH+SEAWFERRTNF RS+A MSMVGYILGLGDRHPSNIML R +GKV+HIDFGDCFEVATMREK+PEKVPFRLTRM+I AMEVTGI+G++RHT +++L+R NRESLLAVLEAF+HDPLLQWVLH+N K+ + DD
Sbjct: 1673 GSVHLRKACLECLARFTDCVDLDDFAGQIIHPICRLLLTLESCHQSYQQLLHQQHHLSSTKSASLGSQACLNAINE----LRVPAMDVLTGLLYRMGQKFKFFLPLVQKMLSRLQLHTP----------RFNTVLGQVEKGAYLPTTSDRAHVKFTSISTRNRAQKLN------VDDSETPGTVKLLKINNTNLERAWHSSRMVSHDDWSQWLKTLNMALLRESPSPAIRACSQLTAITPGIGRTLFNAAFLSCWPELNYHQQDDLINTLERVL-RVPDQSPEVSQTILNLEEFMAHMDKYSSSSHRVHLPLPLGVLADRALKNRAYAKALYYKEQEFLMESEKRSCPSPATLSSLLTIYSKLNLEEAANGVLLYATRSTQDKLANEEVWREKLHDWKSALNLYERKLEDD--RIKDKSSLILGRMRCLRALGQWAPLNNMAWERWNDVNDQVRALMAPLACSAAWALNSWDRVERYTEALSADNSFDGAFYRAVLNIHSEQYAKACDFIMKARDVLDSNLTAMAEESYNRAYADLVGTQLLSEAEEVIQYKLIPERRSILREAWQSRLLGCNSVIEDWSQIIQLRSLVLEPYEDRRSWLRFAGLCRRSGRFILSRQVLENLLGLDPAGIPPCDPIPSSDPAIVFGYTKLLWAVGAHEEAVSRLCVLKTHVLEPLLRAETGINSAQQSSVFQLLSPNLLNANETLDGLDSRQIEIQIINER--KELRRLLAKCCLKLGSWYSELYTRSPPGGHQIDNHSLAYTPNSVFTAASGNGLQFSVAAAARTLSKVNSNSDVIDNIHPSQMSRGAGMRLSNNYSGIVVGGRESSNRNGSRIRRTASAAG---GTSVVNENLATSNITQTWEESQAFVIQCYQTATLHAPDCRNTWQSWAMANYAVFNHLDTLKACLERAELELNKVGGIDNHSLWTSRRNFSSSTGIHGSGVNHMQ--SSNLPVGNISSNFSPLPPPIAELVRAKTDLQRCM-----ELHAAPSVKGFVNSISLSPTANLQDSLRLINLLFKFGHLTEIREVIREGLTKIRLDNWLLVIQQLLARIDTPREYVATIIIDLLISVGQRYPQSMVYPLVLAFKSGGSDRRRYNANRILYSMEEQNSRLISEAFLLNEELIRLSITWVEMWSEALEDASRVYFGEKDIAKMFRLLHPLHQMMDRGHETIHEATFLQENGNDLAESRLCCERYELTQVRIDLQKAWEGYYTLYRRFAKQVNNMTTLELTVSSPRLHEYGQDWQLAVPGSYEPHRPLVRIASIKNCLTFITSKQRPRKLTITGSNGHQYVFLLKGHEDTRQDERIMQFFGLVNTLLINNPETLRRNLTIQRMSVIPLSTYTGLIGWVPNSDTFHNLIRDYREKADVVLNKENREMLRLAPDFDRLNVIQKTEIFEAGLRESSGRDLANILWLKSHSSEAWFERRTNFTRSMATMSMVGYILGLGDRHPSNIMLSRVTGKVVHIDFGDCFEVATMREKFPEKVPFRLTRMIISAMEVTGIDGVYRHTCEMVMSLLRSNRESLLAVLEAFIHDPLLQWVLHENRKEFNHLENKLDD 3200 HSP 2 Score: 260.766 bits (665), Expect = 2.489e-65 Identity = 128/323 (39.63%), Postives = 213/323 (65.94%), Query Frame = 1
Query: 2713 VEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLM-GVFQQTLVDALEGSVRSILELLPEFEYSIEEHVH 3678
EPT V +A+ + LA V + ++ + +P L YMMQD++ KR +AV TL++LV+HTGYVV PY+++P+LL +LL ML+ EE+ IR+EV++ LG +GALDPFK K + ++D+ D G+ VS HE +E+K+VD++Q+EL++N W+ D F++ CAL +L LRDP S Y I I+ + K LGP SV YL+Q++P+YFRC+ +D R Q+ + QL + +V+L+ K+F ++I++L+ W + + CI LL ++ LGA+ + +L+ L+ + + ++ E ++ ++LE+LPEF Y+++++ H
Sbjct: 1237 TEPTPVIVALFTTLGRLAAVAPRSIYHYMDEFIPILAYMMQDTSCFLKRSIAVWTLTRLVSHTGYVVIPYKRYPQLLNILLGMLKREEIKCIRQEVLRALGVLGALDPFKFKLYSGQVDTYGDTGIAVSHHEVVERKDVDITQSELVINLSWESRDVFFSVCALSALIHSLRDPALHSQYGSIVHTIVYVLKLLGPRSVIYLRQLIPDYFRCLENTRDARLQEFLIRQLGNVMTIVQLNTKEFAHEVIDLLITHWWIAPNVQRACIGLLSPMSSVLGAEFRTYLTRLIPTILRMFHHESNESNLIALLEVLPEFGYTLKDYAH 1559 HSP 3 Score: 235.728 bits (600), Expect = 1.029e-57 Identity = 129/261 (49.43%), Postives = 173/261 (66.28%), Query Frame = 1
Query: 1924 IALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYR-KGSIDIVDNLVAT 2703
+AL+TL F+FD H L+ FVR I IS TC KE+RLEAVKTCA L+ P L + + + ++ R L VADVL KLL V SDP+ DVR CVF SFD+RFD +LAQ HL+ LF+A YDE+F+IR LV++ LGRLS INP+C++PNLRK+LL TL +L SGS+RNKEQ+A +LA LI TAP F+ +SE L+ +LLPRI+ + A S + +F+ +I SS ++P R SI ++ N++ T
Sbjct: 775 LALKTLGSFNFDGHTLAHFVRHICDNFISISTCEVKEIRLEAVKTCAHLMIPWLKSTETQQWYA-RPALNTVADVLNKLLTVGISDPDPDVRRCVFLSFDQRFDLHLAQSDHLNYLFLALYDEVFDIRCLVMQRLGRLSDINPACVQPNLRKVLLHTLNDLSHSGSTRNKEQSALLLACLIATAPRFLIPYSEPLIHILLPRIRQALPA--SLRASLIVTSFSRLQNSTFTNNKEIDCSSSLLPAERLPASIQLIQNVILT 1032 HSP 4 Score: 174.866 bits (442), Expect = 2.255e-39 Identity = 74/139 (53.24%), Postives = 95/139 (68.35%), Query Frame = 1
Query: 8260 RIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPWFGCYNTALKMRKRATDGSIIVERNGLEGLIFSAKSPISDRPNYDDTEDEWAGANMRAMDVMKHIKNKLEGKEVGGNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
R+FT+ N+PDS +LR+P VNQWRHHLCNGPWFGCY TA ++RK+ G I+VER+GL+G IFSAK P ++ D N+RA VM+ I+ KL G E ++ VD L+++AT N NLCQMY GWCAFW
Sbjct: 3300 RVFTNPNHPDSASLRDPQKVNQWRHHLCNGPWFGCYETAKRLRKQMESGHIVVERHGLQGFIFSAKPPSTEDSCIDSESQPVTLGNVRARSVMERIRQKLTGTERDQVMSVSAQVDFLIREATSNQNLCQMYIGWCAFW 3438 HSP 5 Score: 152.525 bits (384), Expect = 1.606e-32 Identity = 103/383 (26.89%), Postives = 191/383 (49.87%), Query Frame = 1
Query: 85 PIDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLISSPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAAREG-------------IGRRRQKVINDTTNQNTASSKLPMVSLGSSQFQKQISQQPVNQLRANDSGILESGKIHIEQDWSQELYSNCIAELLRT------LXXXXXXXHI-NSRKLNQESWSHGTXXXXXXXXXXSNDEMEMNRIQLERMIGLSLDQLSSSPMPSGVLSARAICRMEWP 1173
P + F+ G+K++S++ + KT E V++ELK+ S++ + +D + +E I+++ + D++E+K ++ MGC+ ++DF+ H++ + + +T D+Q++AL+ARLI Q L+ + +E Q K +CS++ D S+ Q+ +A L +E + T F Q I ++L +RDK + RE+ +AL AF +TA RE +G N ++ S+++ + G+S+ + + + ++ W Y +C+ E +RT L SSH +SRKLN++ W HG +L+L ELL + ++L++M GL L + + G L+ R + WP
Sbjct: 5 PNSLISQFVQGIKSRSEDDRFKTVAELCKVVSSELKEVSNQNYVICLDLLCNELINIVSNGDVHEKKGAIVAMGCLAEVDFMSVHNHCQRFVKQLLTQSVTTDLQLTALEARLIGQLGLVFPYDFIEEQTKNACSILSKD-ISDAQKHFAILTLREFILHTPTSFCQHMGSFITAILSALRDKNSITRELAGVALRCAFILTAKREQRRYRTYLSVDHSRMGEGPGSFSNLEGGASSVSNRMFFSATGNSRHKTNPNSMSTVNFPGLGYSVSDTNSTSSPFIW----YRDCLIESIRTQSEPAPLILQEQSSHTSSSRKLNRDDWIHGNILILQELLFCVQPQFSKLLMELDQMCGLPLFEFLTVSHSEGSLAVRTVLSTRWP 382 HSP 6 Score: 94.3597 bits (233), Expect = 5.330e-15 Identity = 57/196 (29.08%), Postives = 106/196 (54.08%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTIHAIPRLAALEVPSQYI-----KQSLDFLHRCIKKEK--PLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPG-KDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNS 1788
S+ C L++ ++ IW ++ + ++ ++ L IPRL AL+ PS++ + ++++ +C++KEK P+ + + I + EF + +L + +I+ LP KD+S KKR P LE S + + L ++ + +++ MV GL+ PLI S K++++ IP L +I LL ++ LMNNS
Sbjct: 449 SEICLCLLLENIDKIWASVLMWINSRNHQIMFLLYKLIPRLVALK-PSEFQDTERQRTVMEWMLQCLRKEKEKPMILLNLSLICYFMGPEFATSNYLTQIFQSIRSYLPTQKDVSNKKRSPALETSAILSVSLFTKSLGPAINESVNQILDAMVASGLNQPLIASFKVIAMHIPRLRKEIQDCLLNNISLVLMNNS 643
BLAST of Tor vs. Ensembl Cavefish
Match: mtor (mechanistic target of rapamycin kinase [Source:NCBI gene;Acc:103042377]) HSP 1 Score: 868.611 bits (2243), Expect = 0.000e+0 Identity = 609/1970 (30.91%), Postives = 1018/1970 (51.68%), Query Frame = 1
Query: 106 FLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAAREGIGRRRQKVINDTTNQNTASSKLPMVSLGSSQFQKQI---SQQPVNQLRANDSGILESGKIHIEQDWSQELY--SNCIAELLRTLXXXXXXXHINSRKLNQESWSHGTXXXXXXXXXXSNDEMEMNRIQLERMIGLSLDQLSSSPMPSGVLSARAICRMEWPYSKMEEHIIQHRSKIHLSQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALE---VPSQYIKQSLDFLHRCIKKEKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLS--VDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSVRSI--LELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPI----ATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
F++GLK+++++ + K AK+ +++V EL++ S +E TF D++ ++ S+D+NE+K ++ + ++ ++ + + S+ + ++++ ++D + + ++ + ++ + E VE ++K + + D ++EG+R A L+ +E++ A T FFQ +++ + D + ++RE AL + TT + T + P Q+ KQ +++ ++ A + G+ + ++H EL S+ E +R D + + K +E GT L ++G S P G LS A+ P +S + S+ CR+L+ + + + + +++ K+P LIQ+TI + +PRLAA + QY+ ++ L C+KKEK + + E +L K + IK LP KD + K+++ + ++ +++ I +++ + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL L + +L+ + + + +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + G + + VADVL KLL+V +DP+ D+R CV S DERFDA+LAQ +L LFVA DE+FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG RNKEQ+A++L L+ AP ++ + E +L L+ +++ PD NP V ++V+ I LA V G ++RK + +L P ++ M+QDS+SL KR VA+ TL + V TGYVVEPYRK+P LL +LL L+TE+ IRRE I++LG +GALDP+K K +D D V + D S +E+LVN LD+FY A A+ +L ++LRDP+ +++ + + IFK LG VQ+L QV+P + I D ++ Q+ ++ VK+H++ +M + ++ + W ++ + I L++ + + LG + K +L L+ + + D G +I L + F ++++++H+LLP I+K+ ++ LQ +K AL+ L RL E+LD +D A RI+ P+ R LD + EL A D L++L+ ++ +++ + P++ K + ++ R++ + +++K +++ E++ ++ R+ R V +++ +++ LQKAW A + +S DDW++WL+ S+ L KES S A+RSC +L L++ LFNA+F+SCW EL++ QQD LI ++E L EV+Q +LNL EFM H ++ LP+ L RA K R YAKAL+YKE EF +KG +P IL L++INNKLQ EAASGV+ YA K + +L+ + W+E L +W AL Y +K++ N ++ EL LGRMRCL+ALG+W L + + V + + KMA + AAW LG +++M +Y IP + +G F RAV+A+ + F A + I KARD LD+ LTAMAGESY RAYG +V Q L+ELEEVIQYKLV E ++ IR+ W +RL+GCQ++++DW+++L +RSLV+ P++DM TWLK+A L +S RL ++ + L G + SK ++ L P + +++ KY W + + A +++ V+ + + + I D+ + L+A+C L+LG+W + LQY Y +TE +AW AWA+ N+ + K++
Sbjct: 11 FVSGLKSRNEDTRAKAAKDLQHYVTTELRELSQDEATTFYDELNHHIFELVSSSDVNEKKGGILAIVSLIGVEG-GNATRISRFANYLRNLLPSSDSVVMEMASKAMGHLSMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAVSAPTFFFQQVQPFFDNIFYAVWDSKQAIREGAVSALRACLIL-----------------TTQRETKEMQKP-------QWYKQTFEEAEKGFDESLAKEKGMNKDDRVHGALLILNELVRISSMEGERMREEMDEITQQQLVHDKYCKELMGFGTKPRHITPFTSFQSVQPPQSNALLGLLGYS--------SPQGFLSFGAV-----PAPS--------KSTLVESRYCRELMEERFDQVCRWVLKYRTTKNP-LIQMTILNLLPRLAAFQPHTFTDQYLSDTMGHLLGCLKKEKERTAAFQALGLLVVAVRTEIQPYLTKILEIIKAALPPKDFAHKRQKTMQVDATVFTCISMLSRAMGPSIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAHQLASPSLTNIPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSIHLISGHGHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDEVFEIRELAICTIGRLSSMNPAFVMPFLRKMLIQILTELEHSGVGRNKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKD--------PD--------------------------------------------PNP-----GVVISVLATIGELAQVSGLEMRKWMDELFPIIMDMLQDSSSLAKRQVALWTLGQQVASTGYVVEPYRKYPSLLEVLLNFLKTEQNQGIRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSADYSTSEMLVNMGNLPLDEFYPAVAIVTLMRILRDPSLSNHHTMVVQAVTFIFKSLGLKCVQFLPQVMPTFLNVI-RVCDASIREFLFQQMGMVVCFVKIHIRPYMDDIFTLIREYWTPNNPMQNTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRSVTIKLLMAIQLFGANLDDYLHLLLPPIVKLFDAPDV--PLQARKVALETLDRLTESLDFTDYASRIIHPIVRTLDGT---------------------------PELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVM----------LRHRINHQRYDVLICRIVKGYTLADEEEDSQIYQH--RQSRGNQGDALVSGPVESGPMKKLH-VSTTALQKAWGAARKVSKDDWLEWLRRLSVVLLKESSSPALRSCWSLAQTYIPLARDLFNAAFLSCWSELSEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEF-----QKGPSPL-ILESLISINNKLQQPEAASGVLEYAMKHF-GELEIQATWYEKLHEWEDALVAYDKKIDMNK----EDPELILGRMRCLEALGEWGQLHQQCCEEWTLVSEETQAKMARMAAAAAWGLGHWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCQMLSELEEVIQYKLVPERRDIIRETWWERLQGCQRIVEDWQRILMVRSLVINPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSK-QLDHPLPTAHPHVTYAYMKYMWKSARKIDAFQHMQHFVQG-------MQQQAQHAIAAEDQQHKQELHKLMARCFLKLGEWQLSLQGINESTIPKVLQY-----YSHSTEHDRNWYKAWHAWAVMNFEAVLHYKHQ 1790 HSP 2 Score: 652.899 bits (1683), Expect = 0.000e+0 Identity = 321/640 (50.16%), Postives = 445/640 (69.53%), Query Frame = 1
Query: 6265 NENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSV 8184
N S + E++ + + + Q ++ + K L++ Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M H LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF +L PLH +MER +T E +F Y DL A++ C +Y S DLTQAW++Y +++R+ +KQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLTI+G +GH +MFLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L +++K EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++R+S++AVLEAF++DPLL W L D KG + + DS +A E + + L + P T+V
Sbjct: 1812 NSEASNSDSEADSADHSPVPSPGQKKVNEDLSKTLLL----YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPEVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMRSGNVKDLTQAWDLYYHVFRRIAKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMEKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTKGTKRSRTRTDSYTAGQSV--ETMEGIDLGETTHKKPGTTV 2444 HSP 3 Score: 55.4546 bits (132), Expect = 1.139e-6 Identity = 22/56 (39.29%), Postives = 37/56 (66.07%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGGNLTSE--EHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ + T + V++L+KQAT + NLCQ Y GWC FW
Sbjct: 2463 NKKAIQIINRVRDKLTGRDFSHDETLDVPTQVELLIKQATSHENLCQCYIGWCPFW 2518
BLAST of Tor vs. Ensembl Cavefish
Match: smg1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:ZFIN;Acc:ZDB-GENE-061013-767]) HSP 1 Score: 226.098 bits (575), Expect = 2.777e-58 Identity = 179/650 (27.54%), Postives = 293/650 (45.08%), Query Frame = 1
Query: 6457 SLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHP------------------QAMVN------PLVLAFKSG----GSDRRRYNA---------------------------NKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLED---------ASRLHY-----------EEKNTTAMFKILYPL-HI--LMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAW----EIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEML------------------KIAPDFEKLNIIQKT-----------EVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGE 8073
+LRL+ LL + H +RE + GL+ W +I QL +R++ + ++ I LL V + P QA N P +L G G + + +A +KI+ ++ + +V + +L EL R+ + W E+W L+ + LHY EK++ M +++ L H+ + ET HE ++ E YG+ + N R ++ + +W +I +L ++ K+ S + L L SPRL + +A+PG V I+++ N + ++ +K P+KL +G DG NY +L KG ED+ DER MQF ++NT+ Q + SV PL T +GLI WV + L + + ++++ VL ++ ++ KI P + + + +V + + LA LW W+ ++ RS AVMSMVGYI+GLGDRH N+++ +G+V+HID+ CFE + PEKVPFR+T + A+ VTG+EG+FR + Q+V +MR+ RE+LL +LEAF++DPL+ W GGE
Sbjct: 1780 TLRLLRLLVK--HAGELREGLELGLASTPTAPWRGIIPQLFSRLNHPEAYIRQSICSLLCRVAQDSPHLILYPAIVGSISLGGESQAAGNKLPSSLPTLLGNMQGEGLCGEESQAGSAPASQESGRGEELVLCSSEDQAMMQDCYSKIVDTLSSGNPTMVLQVQMLVGELRRVTLLWDELWLGVLQQQHMHVLQLQSIHLHYYPLLDEKMAIMREKHSALMRPVVFALDHVRSITAAPAETPHET-WFQETYGE--AIHNALERLKNPLNPANPASSWVPFKQIMVSLQQRAQKRASYL--LRLDEISPRLASMANTEMALPGEVSATDA-VTIHNVGNTITILPTKTKPKKLYFLGSDGKNYPYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAVLQAQKAQDSYQQPQNLPMVPRPSELYYSKIGPALKAVGLSLDVSRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSL-RVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQMMRRGRETLLTLLEAFVYDPLVDWT------AGGE 2414
BLAST of Tor vs. Ensembl Cavefish
Match: atr (ATR serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-070912-458]) HSP 1 Score: 182.57 bits (462), Expect = 3.552e-45 Identity = 104/299 (34.78%), Postives = 168/299 (56.19%), Query Frame = 1
Query: 7168 AIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVI-RDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSH-NSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDF------GDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
A PG + V ++ + + ++ S Q P+K+++ G DG Y + K +D+R+D R M+F LIN + + ++ R +L I+ +VIPL+ G+I WV N+ L ++ + Y+EK L +E ++M+ K +Q+ + + + H +L++ + +W+ R+ + RS AVMSMVGY+LGLGDRH NI+ +G+ +H+DF G+ F+V PE VPFRLT+ ++ AM G EGLFR + LMR RE L++VL+ FLHDPL++W
Sbjct: 2076 AFPGHW------VYLSGFDDSVEILASLQKPKKISLRGSDGKFYTMMCKPKDDLRKDCRLMEFNCLINKCLRKDAESRRRDLHIRTYAVIPLNEECGIIEWVNNTAGLRHILNKLYKEKGIYLTGKELRKMI-----LPKTASLQEKLKLHKDVLCARHPPVFHDWFLRTFPDPTSWYNSRSAYCRSTAVMSMVGYVLGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFDV-------PEVVPFRLTQNMVHAMGPMGTEGLFRQACEVTLRLMRDQREPLMSVLKTFLHDPLVEW 2356
BLAST of Tor vs. Ensembl Cavefish
Match: prkdc (protein kinase, DNA-activated, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-030131-9008]) HSP 1 Score: 165.236 bits (417), Expect = 9.226e-40 Identity = 115/377 (30.50%), Postives = 190/377 (50.40%), Query Frame = 1
Query: 7141 LHDYNDWI-----------LAIPGSYDP-NRPI----VKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYR-EKTQVLLNR--------------EHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLK-SHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW--VLHDNTKKGGENTVETDDSLSAN---IDAINELRKALQLHVNP 8160
L +Y+ W+ L +PG YD ++P+ KI + +MTS + P++L + GDD ++ FL+KG ED+RQD+R Q FG++N ++ + S+ +L ++ VIP+++ GLI W+ N+ TL + R EK Q + R + + +++ A + K N F+ I ++ +DL +++ S EA+ R++F S A++ + ++LG+GDRH SN M+ ++G +I IDFG F AT PE +PFRLTR + M GL R + + R + E LL ++ F+ +P L W KKGG T E+ D+ N + +N R+ L+ NP
Sbjct: 3637 LKEYSPWLSNFRVETLRSELEVPGQYDGRSKPLPEYHAKITGFDERVKVMTSIRRPKRLIVRGDDEKDHPFLVKGGEDLRQDQRIEQLFGVMNIILSQDAACSQRSLMLRTYQVIPMTSRIGLIEWMENTCTLKDFLASRRTEKEQKTITRPNEIYDAWISKAAGKSEGIMRYAEVYRKANRTDTVNNFKK-IEQTVPEDLLRRAFVRMSTTPEAFLSLRSHFASSHALLCISQWVLGIGDRHLSNFMINTETGGMIGIDFGHAFGSATQFLPVPELMPFRLTRQFVNLMRPMAESGLIRSVMVHSLRAYRDDPELLLNTMDVFVKEPSLDWKNFAVKQLKKGGTWT-ESVDTQEINWYPLQKVNFARRKLE-GANP 4010
BLAST of Tor vs. Ensembl Cavefish
Match: atm (ATM serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040809-1]) HSP 1 Score: 161.77 bits (408), Expect = 9.327e-39 Identity = 90/291 (30.93%), Postives = 154/291 (52.92%), Query Frame = 1
Query: 7201 IVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRD--------YREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLH 8049
+V I+S K +L P+ + +G DG + L+KG +D+RQD Q F + +TL+ N +T + L+I+R V+P S +G++ W + + + D +R + L K M +F+K K + F + + ++ + + + W E+R + RS+A S+VGYI+GLGDRH NI++ + +++HID G FE + PE VPFRL+R ++ M +TG+EG+FR + + +MR ++E LL ++E L+DPL W ++
Sbjct: 2677 LVTISSFKPHFHLAGGVNLPKIIDCVGSDGKSRRQLVKGQDDLRQDAVMQQVFHMCSTLLQRNAETRKRKLNIRRYKVVPFSQRSGVLEWCSGTVPIGEFLVDPQKGAHKRFRPQDWTSLACRKKMMEAQRMEFDK-----KLQAF-TEVCQNFRPVFRYFCMERFLDPAVWLEKRLAYTRSVATSSIVGYIVGLGDRHIQNILIDEQTAELVHIDLGVAFEQGKILPT-PETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQEVLLTIVEVLLYDPLFDWTMN 2960
BLAST of Tor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007186.1 (pep scaffold:Pmarinus_7.0:GL476459:175296:202639:-1 gene:ENSPMAG00000006485.1 transcript:ENSPMAT00000007186.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 165.236 bits (417), Expect = 7.200e-41 Identity = 96/295 (32.54%), Postives = 152/295 (51.53%), Query Frame = 1
Query: 7201 IVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAP-DFEKLNIIQKTEVFESGIRESD----GKDLA--------HILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVL 8046
+V + + + L P+ + G DG Y L+KG +D+RQD Q F + N L+ + +T LSI+ V+PLS +G++ W + I DY L+ ++ K P D+ ++ + V R D ++L H W + + WFERR ++ RS+A S+VGYI+GLGDRH NI++ +S +++HID G FE + PE VPFRLTR ++ M +TG+EG+FR + + +MR ++E+LL ++E L DPL W +
Sbjct: 717 LVTVRAFRPHFRLAGGVNLPKIIDCEGSDGRTYRQLVKGRDDLRQDAVMQQVFHMCNELLAGSAETRTRKLSIRTYKVVPLSQRSGVLEWCVGT----MPIGDY------LVQKDTGAHTKYRPNDWPSMHCRKFMNVAAQDRRNGDLFLAYQELCHHFRPVFRHFFWERFLDPAVWFERRLSYTRSVATSSIVGYIVGLGDRHVQNILIDLNSAELVHIDLGVAFEQGRILPT-PETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQEALLTIVEVLLFDPLFDWTM 1000
BLAST of Tor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003429.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003429.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 163.696 bits (413), Expect = 4.530e-40 Identity = 112/345 (32.46%), Postives = 184/345 (53.33%), Query Frame = 1
Query: 7174 PGSYDPNRP----IVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINT-LMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRD-YREK-TQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSH-NSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLL---AVLEAFLHDPLLQWV--LHDNTKKGGENTVETDDSLSANIDAINELRKALQLHV-NPNN 8166
PG + + P + I + + +++S Q P+K+ I G DG +Y + K +D+R+D R M+F LIN L+ + ++ R +L I +VIPL+ GL+ WV N+++L ++ Y EK + ++ K +L I E QK ++ + + H +L++ + +W+ R + RS AVMSMVGY+LGLGDRH NI+ +G+ +H+DF +C + PE VPFRLT ++ AM G+EGLFR + +M RESL+ +VL+ F+HDPL++W LH + + E + + I + ++ + L + NPNN
Sbjct: 2268 PGGHADHDPFPGNMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKDAESRRRDLRICTYAVIPLNEECGLVEWVNNTESLRTIVDILYNEKGIGLTMSEVSKCILPIETPLE-----QKLSMYRDKLLPPH-PPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDF-NCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWSRPLHGSWRGSANEAGEVVNEKAKQI--VQDIEQRLHGVIKNPNN 2603
BLAST of Tor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003412.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003412.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 163.696 bits (413), Expect = 4.828e-40 Identity = 112/347 (32.28%), Postives = 185/347 (53.31%), Query Frame = 1
Query: 7168 AIPGSYDPNRP----IVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINT-LMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRD-YREK-TQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSH-NSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLL---AVLEAFLHDPLLQWV--LHDNTKKGGENTVETDDSLSANIDAINELRKALQLHV-NPNN 8166
+ PG + + P + I + + +++S Q P+K+ I G DG +Y + K +D+R+D R M+F LIN L+ + ++ R +L I +VIPL+ GL+ WV N+++L ++ Y EK + ++ K +L I E QK ++ + + H +L++ + +W+ R + RS AVMSMVGY+LGLGDRH NI+ +G+ +H+DF +C + PE VPFRLT ++ AM G+EGLFR + +M RESL+ +VL+ F+HDPL++W LH + + E + + I + ++ + L + NPNN
Sbjct: 2300 STPGGHADHDPFPGNMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKDAESRRRDLRICTYAVIPLNEECGLVEWVNNTESLRTIVDILYNEKGIGLTMSEVSKCILPIETPLE-----QKLSMYRDKLLPPH-PPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDF-NCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWSRPLHGSWRGSANEAGEVVNEKAKQI--VQDIEQRLHGVIKNPNN 2637
BLAST of Tor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003421.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003421.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 163.31 bits (412), Expect = 5.241e-40 Identity = 112/347 (32.28%), Postives = 185/347 (53.31%), Query Frame = 1
Query: 7168 AIPGSYDPNRP----IVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINT-LMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRD-YREK-TQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSH-NSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLL---AVLEAFLHDPLLQWV--LHDNTKKGGENTVETDDSLSANIDAINELRKALQLHV-NPNN 8166
+ PG + + P + I + + +++S Q P+K+ I G DG +Y + K +D+R+D R M+F LIN L+ + ++ R +L I +VIPL+ GL+ WV N+++L ++ Y EK + ++ K +L I E QK ++ + + H +L++ + +W+ R + RS AVMSMVGY+LGLGDRH NI+ +G+ +H+DF +C + PE VPFRLT ++ AM G+EGLFR + +M RESL+ +VL+ F+HDPL++W LH + + E + + I + ++ + L + NPNN
Sbjct: 2286 STPGGHADHDPFPGNMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKDAESRRRDLRICTYAVIPLNEECGLVEWVNNTESLRTIVDILYNEKGIGLTMSEVSKCILPIETPLE-----QKLSMYRDKLLPPH-PPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDF-NCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWSRPLHGSWRGSANEAGEVVNEKAKQI--VQDIEQRLHGVIKNPNN 2623
BLAST of Tor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010422.1 (pep scaffold:Pmarinus_7.0:GL478779:2292:46075:1 gene:ENSPMAG00000009431.1 transcript:ENSPMAT00000010422.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 153.68 bits (387), Expect = 4.499e-37 Identity = 125/472 (26.48%), Postives = 208/472 (44.07%), Query Frame = 1
Query: 6727 NKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMW--------------TECLEDASR-------LHYE-------EKNTTAMFKILYPL---HILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVST--LELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFE-SGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
+KI+ + S +VS+ LL EL R+ + W E+W + LED + L E EK+T M +++ L H + ET HE F + Y +S+A R ++ +W + L + ++ ++ L L+ SPRL +A+PG R V ++S+ ++++ +K P+KL+ + DG+ Y +L KG ED+ DER MQF ++N + V + SV PL + +GLI WV + L + + ++++ E L K E+ S IR +D + ++ NF+R L ++ + K + + FEV PEKVPFR+T+ + A+ VTG+EG+FR + QI+ +MR+ RE+LL +LEAF++DPL+ W
Sbjct: 1883 SKIVDKLMASSPTMVSQVQLLVSELRRITVLWDELWLGVLLQQQMMALRRVQQLEDEGKRVQANVTLRKEEKLAIMREKHTALMKPVVFALEHAHSITSASPETPHERWFQDTYGASISAALE---RLKNPPNPASPGASWAPFRQLLQSLQQRAQKRTSYLLRLAEMSPRLSALAGTEMALPGESH-AREAVCVHSLAPSVSILPTKTKPKKLSFLASDGNTYTYLFKGLEDLHLDERIMQFLSIVNNMFVKGNGREWHRFHARHYSVTPLGSRSGLIQWVDGATPLFGLYKRWQQR-------------------ETLTAGHKVELVPCSRIRLADPR-----------------KQIKNFLRHLRECAVSSF-------------------KSVRVTKARAFEV-------PEKVPFRMTQDIERALGVTGVEGIFRLSCEQILQIMRRGRETLLTLLEAFVYDPLVDW 2288
BLAST of Tor vs. Ensembl Yeast
Match: TOR1 (PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis; TOR1 has a paralog, TOR2, that arose from the whole genome duplication [Source:SGD;Acc:S000003827]) HSP 1 Score: 549.28 bits (1414), Expect = 1.058e-158 Identity = 274/561 (48.84%), Postives = 381/561 (67.91%), Query Frame = 1
Query: 6397 PAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENT 8079
PA++GF ++ISL T+ LQD+LRL+ LLF F I + + + +G + + +ENWL V+ QL++RI VS+ ++ LL +G+ HPQA+V PL +A KS R++ A I+ + +HS LV++A L++ ELIR+ + W E+W E LEDASR + E N MF L PLH + E +T EV+F + DL+ A Y+ S +L QAW+IY N++RK ++QI + TL+L SP+L +D LA+PG+Y P +P ++I + ++++SKQ PRK +I G DG +Y ++LKGHEDIRQD MQ FGL+NTL+ ++ + + +L IQ+ IPLS +GL+GWVPNSDT + +IR++R+ ++ LN EH ML++APD+E L ++QK EVF + + G+DL ILWLKS +SE W ERRT + RSLAVMSM GYILGLGDRHPSN+ML R +GKVIHIDFGDCFE A +REKYPEKVPFRLTRML AMEV+GIEG FR T ++ ++R N+ESL+A+LEAF DPL+ W +K E T
Sbjct: 1820 PAIKGFFHSISLLETSCLQDTLRLLTLLFNFGGIKEVSQAMYEGFNLMKIENWLEVLPQLISRIHQPDPTVSNSLLSLLSDLGKAHPQALVYPLTVAIKSESVSRQK-AALSIIEKIRIHSPVLVNQAELVSHELIRVAVLWHELWYEGLEDASRQFFVEHNIEKMFSTLEPLHKHLGNEPQTLSEVSFQKSFGRDLNDAYEWLNNYKKSKDINNLNQAWDIYYNVFRKITRQIPQLQTLDLQHVSPQLLATHDLELAVPGTYFPGKPTIRIAKFEPLFSVISSKQRPRKFSIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLKNDSECFKRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHRDAKKIPLNIEHWVMLQMAPDYENLTLLQKIEVFTYALDNTKGQDLYKILWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMRVLRDNKESLMAILEAFALDPLIHWGFDLPPQKLTEQT 2379 HSP 2 Score: 507.679 bits (1306), Expect = 1.439e-145 Identity = 418/1543 (27.09%), Postives = 753/1543 (48.80%), Query Frame = 1
Query: 1408 IKKEKPLSYITMGFIAH-----IAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVI-KEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFV-----------RFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV-DALEGSV--RSILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIAT----LESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFD-LLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQET---IRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERI--NNIQIVDESC---VKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICM 5937
+K +KP I++G IA+ IAP ++++ + I+ +L K KK E I+ IG +A + ++ + ++ M + LS + + ++++ IP L I+ LL + TL +P S S E E RNK I +T E + D +++ + + RF + + + SY E V+ A L + + D+ + ++L V++VL KLL ++ +DP +D+RL V ++ + FD LAQ +L LF A +DE F I+ + + +GRLS++NP+ + P++RKILL+ LT+L+FS SSR KE+ A +L LI ++ + + E LL ++++P ++ S + V ++ I L+VV G ++ +L DL P +I QD ++ KR A+ L +L +GYV++P +PELL +L+ +L+TE +IRR+ + L+G +GA+DP++QK+ E+ S D+ + E+ + A LL+ D++YT + L ++L+DP+ S + + I+ IF+ LG V +L Q++P +M + + QLC + +V+ H++ + + + ++ ++ KL + + ++++++ L + K + + +F L D V R +L LL F ++E + H++ P I+++ ++ ++++A+ + +LA+ +DL + + RIV + R+L ++ ++++L+++I + L+ LL++M F + P+I + L +K H ++ N N VL + E N ++ + + + +P IN L+ AW + + + +DW +W K SI L KESPS+A+R+CSNL L+K LFN +F W EL Q++LI + L S LN E+ Q +LNL EFM H ++ LPI T +L A + YAKAL+YKE +F++E P+N + L++INN+L +AA G++ +A + LQ +E W E L+ W AL+ Y + + D+ + +TLG+MR L ALG+W L + ++ K +AP+ AAW LG+++ + +Y+ + + + F A++ + ++ AS++I ARD L + ++A+ ESY RAY +V Q + E EE+I+YK + + E + W RL GCQ+ +D W+++L++RSLV+ P QD+ W+KFA L R+S R+ ++ ++ L + S N P ++++ KY W TG ++ AL +L + +L +D+ + + ++++ S V+ LLA+C L+ G+W +A + + + N I+ +Y +AT +AW WA+AN+ +I M
Sbjct: 401 LKDDKPQILISIGDIAYEVGPDIAP-------YVKQILDYIEHDLQTKFKFRKK----FENEIFYCIGRLAVPLGPVLGKLLNRNILDLMFKCPLSDYMQETFQILTERIPSLGPKINDELLNLVCSTLSGTPFIQPGSPMEIPSFSRERAR--------------------EWRNKNILQKT-GESNDDNNDIKIIIQAFRMLKNIKSRFSLVEFVRIVALSYIEHTDPRVRKLAALTSCEIYVKDNICKQTSLHSLNTVSEVLSKLLAITIADPLQDIRLEVLKNLNPCFDPQLAQPDNLRLLFTALHDESFNIQSVAMELVGRLSSVNPAYVIPSIRKILLELLTKLKFSTSSREKEETASLLCTLIRSSKDVAKPYIEPLL-------------------------------------------NVLLPKFQDTS----------------STVASTALRTIGELSVVGGEDMKIYLKDLFPLIIKTFQDQSNSFKREAALKALGQLAASSGYVIDPLLDYPELLGILVNILKTENSQNIRRQTVTLIGILGAIDPYRQKE--REVTSTTDI--------STEQNAPPIDIA-LLMQGMSPSNDEYYTTVVIHCLLKILKDPSLSSYHTAVIQAIMHIFQTLGLKCVSFLDQIIPTILD-VMRTCSQSLLEFYFQQLCSLIIIVRQHIRPHVDSIFQA-IKDFSSVAKLQITLVSVIEAISKALEGEFKRLVPLTLTLFLVILENDKSSDKVLSRRVLRLLESFGPNLEGYSHLITPKIVQMAEF----TSGNLQRSAIITIGKLAKDVDLFEMSSRIVHSLLRVL----------------------SSTTSDELSKVI---MNTLSLLLIQMGTSFAIFIPVINEVL--MKKHIQHTIYDDLTNRILN---NDVLPTKIL---EANTTDYKPAEQMEAADAGVAKLP-------------INQSVLKSAWNSSQQRTKEDWQEWSKRLSIQLLKESPSHALRACSNLASMYYPLAKELFNTAFACVWTELYSQYQEDLIGSLCIALSSPLN---PPEIHQTLLNLVEFMEHDDK-ALPIPTQSLGEYAERCHAYAKALHYKEIKFIKE-------PENSTIESLISINNQLNQTDAAIGILKHAQQ--HHSLQLKETWFEKLERWEDALHAYNEREKAGDT----SVSVTLGKMRSLHALGEWEQLSQLAARKWKVSKLQTKKLIAPLAAGAAWGLGEWDMLEQYISVMKPKSPDKEFFDAILYLHKNDYDNASKHILNARDLLVTEISALINESYNRAYSVIVRTQIITEFEEIIKYKQLPPNSEKKLHYQNLWTKRLLGCQKNVDLWQRVLRVRSLVIKPKQDLQIWIKFANLCRKSGRMRLANKALNMLLEGG-NDPSLPNTFKAP-PPVVYAQLKYIWATGAYKEALNHL-IGFTSRLAHDLGLDPNNMIAQSVKLSSASTAPYVEEYTKLLARCFLKQGEW---RIATQPNWRNTNPD-AILGSYLLATHFDKNWYKAWHNWALANFEVISM 1765 HSP 3 Score: 56.6102 bits (135), Expect = 7.840e-8 Identity = 27/65 (41.54%), Postives = 36/65 (55.38%), Query Frame = 1
Query: 8488 DTEDEWAGANMRAMDVMKHIKNKLEGKEVG--GNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
+ E + N RAM V++ I +KL G ++ L E VD L++QAT LCQ Y GWC FW
Sbjct: 2406 EAEQQNETKNARAMLVLRRITDKLTGNDIKRFNELDVPEQVDKLIQQATSIERLCQHYIGWCPFW 2470
BLAST of Tor vs. Ensembl Yeast
Match: TOR2 (PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis; TOR2 has a paralog, TOR1, that arose from the whole genome duplication [Source:SGD;Acc:S000001686]) HSP 1 Score: 535.798 bits (1379), Expect = 2.284e-154 Identity = 275/562 (48.93%), Postives = 383/562 (68.15%), Query Frame = 1
Query: 6397 PAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGS-YDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENT 8079
PA++GF ++ISLS +++LQD+LRL+ L F F I + + +G + I + WL V+ QL++RI + VS ++ LL +G+ HPQA+V PL++A KS R++ A I+ M +HS LV +A L++ ELIR+ + W E W E L+DASR + E NT MF L PL+ +++R ET E++F N + DL+ A + Y+ S ++L QAW+IY N++RK KQ+ + TLEL SP+L +D LA+PG+ +PIVKI+ + ++++SKQ PRK I G DG +Y ++LKGHEDIRQD MQ FGL+NTL+ ++ + R +L IQ+ IPLS +GL+GWVPNSDT + +IR++RE ++ LN EH ML++APD++ L ++QK EVF + ++G+DL +LWLKS +SE W ERRT + RSLAVMSM GYILGLGDRHPSN+ML R +GKVIHIDFGDCFE A +REK+PEKVPFRLTRML AMEV+GIEG FR T ++ ++R N+ SL+A+LEAF DPL+ W TKK E T
Sbjct: 1823 PAIKGFFHSISLSESSSLQDALRLLTLWFTFGGIPEATQAMHEGFNLIQIGTWLEVLPQLISRIHQPNQIVSRSLLSLLSDLGKAHPQALVYPLMVAIKSESLSRQK-AALSIIEKMRIHSPVLVDQAELVSHELIRMAVLWHEQWYEGLDDASRQFFGEHNTEKMFAALEPLYEMLKRGPETLREISFQNSFGRDLNDAYEWLMNYKKSKDVSNLNQAWDIYYNVFRKIGKQLPQLQTLELQHVSPKLLSAHDLELAVPGTRASGGKPIVKISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLQNDAECFRRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREAKKIPLNIEHWVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAFDPLINWGFDLPTKKIEEET 2383 HSP 2 Score: 481.485 bits (1238), Expect = 2.170e-137 Identity = 429/1578 (27.19%), Postives = 759/1578 (48.10%), Query Frame = 1
Query: 1312 LIQLTIHAI-PRLAALEVPSQYIKQSLD--FLH--RCIKK---------EKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVI-KEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLVDALEGSVRS-------ILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPST-EVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFD-LLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQE---TIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDES-----CVKNSRILLAKCALRLGDWYTESLAK----ETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICM 5937
+I+ ++AI P LAA + P+ + K+ LD +H R +K +KP +++G IA FE + +T I N+ + K + E ++ IG +A + K+++ M+ +S + +L +++ IP L + ++ +L L +L + + ++ S+E N S + S D I +I +++ +++L+ FVR I T SY E +V+ A L + L DD + + L +V++VL KLL+++ +DP ++RL + Q FD LAQ +L LF+A DE+F I+ I+ +GRLS++NP+ + P+LRK LL+ LT+L+FS + KE++A +++C + D + K Y +++P + S +AV ++ + L+VV G ++ ++L +L+P +I QD ++ KR A+TTL +L +GYVV P +PELL +L+ +L+TE IRR ++L+G +GALDP+K + ++ + + ++E+ + A LL+ D++Y + +L ++L DP+ ++ I+ IF+ LG V +L Q++P +M + + QL + +VK H++ + ++ ++ + + KL + I +++S++ L + K F+ + F +D LE + IL+ L F ++E++ H+++P ++++ S +KK ++ L RLA+ ++LS+ + RIVQ + R+L N EL + L+ LL+++ F+V P+I K L + + ++ +NK+L + + D+ RK E+ + ++ + Q I L+ AW + + +DW +W++ SI L KESPS +RSCS+L L++ LFNASF SCW EL + Q++LI L L+ + E+ Q +LNL EFM H ++ LPI L A K +AKAL+YKE EFLEE P+N + L++INN+L ++A G++ +A + ++LQ +E W+E LQ W AL Y K ++ + E+ +G++R L ALG+W L + +++ +K MAP+ AAW L ++ + +Y + + + F A++ + F +A +I ARD L + L+A+ ESY RAY +V AQ +AELEE+I+YK + ++ + T+R+ W RL GCQ+ ID W+++L++RSLV+ P +D +KFA L R+S R+ ++K +++ L E N P ++++ KY W TG AL L + ++ +D+ + + + +S V++ LLA+C L+ G+W K D+ I+ +Y +AT +AW WA+AN+ +I M
Sbjct: 365 VIRREVYAILPLLAAFD-PAIFTKKYLDRIMVHYLRYLKNIDMNAANNSDKPFILVSIGDIA------FEVGSSISPYMTLILDNIREGLRTKFKVRKQFEKDLFYCIGKLACALGPAFAKHLNKDLLNLMLNCPMSDHMQETLMILNEKIPSLESTVNSRILNLLSISLSGEKFIQSNQYDFNNQFSIEKARKSRNQ--SFMKKTGESNDDITDAQILIQCFKMLQLIHHQYSLTEFVRLI--------TISYIEHEDSSVRKLAALTSCDLFIKDDICKQTSVHALHSVSEVLSKLLMIAITDPVAEIRLEILQHLGSNFDPQLAQPDNLRLLFMALNDEIFGIQLEAIKIIGRLSSVNPAYVVPSLRKTLLELLTQLKFSNMPKKKEESA------------------------------TLLCTLINSSDE-------------VAKPYIDPILDVILPKCQDAS----------------SAVASTALKVLGELSVVGGKEMTRYLKELMPLIINTFQDQSNSFKRDAALTTLGQLAASSGYVVGPLLDYPELLGILINILKTENNPHIRRGTVRLIGILGALDPYKHR----------EIEVTSNSKSSVEQNAPSIDIA-LLMQGVSPSNDEYYPTVVIHNLMKILNDPSLSIHHTAAIQAIMHIFQNLGLRCVSFLDQIIPGII-LVMRSCPPSQLDFYFQQLGSLISIVKQHIRPHVEKIYGVIREFF-PIIKLQITIISVIESISKALEGEFKRFVPETLTFF----LDILENDQSNKRIVPIRILKSLVTFGPNLEDYSHLIMPIVVRMTEY----SAGSLKKISIITLGRLAKNINLSEMSSRIVQALVRIL--------------------------NNGDRELTKATMNTLSLLLLQLGTDFVVFVPVINKAL----------LRNRIQHSVYDQLVNKLLNNECLPTNII-FDKENEVPERKNYEDE-------MQVTKLPVNQNI----LKNAWYCSQQKTKEDWQEWIRRLSIQLLKESPSACLRSCSSLVSVYYPLARELFNASFSSCWVELQTSYQEDLIQALCKALSSSENPPEIYQMLLNLVEFMEHDDK-PLPIPIHTLGKYAQKCHAFAKALHYKEVEFLEE-------PKNSTIEALISINNQLHQTDSAIGILKHAQQ--HNELQLKETWYEKLQRWEDALAAYNEK----EAAGEDSVEVMMGKLRSLYALGEWEELSKLASEKWGTAKPEVKKAMAPLAAGAAWGLEQWDEIAQYTSVMKSQSPDKEFYDAILCLHRNNFKKAEVHIFNARDLLVTELSALVNESYNRAYNVVVRAQIIAELEEIIKYKKLPQNSDKRLTMRETWNTRLLGCQKNIDVWQRILRVRSLVIKPKEDAQVRIKFANLCRKSGRMALAKKVLNTLL-EETDDPDHPNTAKAS-PPVVYAQLKYLWATGLQDEALKQL-INFTSRMAHDLGLDPNNMIAQSVPQQSKRVPRHVEDYTKLLARCFLKQGEWRVCLQPKWRLSNPDS--------ILGSYLLATHFDNTWYKAWHNWALANFEVISM 1772 HSP 3 Score: 60.4622 bits (145), Expect = 4.636e-9 Identity = 30/65 (46.15%), Postives = 39/65 (60.00%), Query Frame = 1
Query: 8488 DTEDEWAGANMRAMDVMKHIKNKLEGKEVG--GNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
+ E + A N RAM V+K I +KL G ++ +L E VD L++QAT NLCQ Y GWC FW
Sbjct: 2410 ENEHKNAIRNARAMLVLKRITDKLTGNDIRRFNDLDVPEQVDKLIQQATSVENLCQHYIGWCPFW 2474
BLAST of Tor vs. Ensembl Yeast
Match: MEC1 (Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres [Source:SGD;Acc:S000000340]) HSP 1 Score: 158.303 bits (399), Expect = 9.987e-39 Identity = 99/285 (34.74%), Postives = 152/285 (53.33%), Query Frame = 1
Query: 7183 YDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYRE--KTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEA--WFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHD 8025
Y P RP+V I + + +S + P++L IIG DG+ Y + K ED+RQD + MQF ++ L+ + + + +L I SV+ L + G++ VPN TL +++ E K + L H A D + +++ + F + + W + + WF R + RS AVM+MVG+ILGLGDRH NI+L +GKV+H+DF DC R PE VPFRLT L+ A+ + G EG F+ +S + LMRKN +L+ V+E ++D
Sbjct: 2037 YQPFRPVVSIIRFGSSYKVFSSLKKPKQLNIIGSDGNIYGIMCK-KEDVRQDNQYMQFATTMDFLLSKDIASRKRSLGINIYSVLSLREDCGILEMVPNVVTLRSILSTKYESLKIKYSLKSLHDRWQHTAVDGKLEFYMEQVDKFPPILYQ----------WFLENFPDPINWFNARNTYARSYAVMAMVGHILGLGDRHCENILLDIQTGKVLHVDF-DCLFEKGKRLPVPEIVPFRLTPNLLDALGIIGTEGTFKKSSEVTLALMRKNEVALMNVIETIMYD 2309
BLAST of Tor vs. Ensembl Yeast
Match: TEL1 (Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; acts with Red1p and Mec1p to promote interhomolog recombination by phosphorylation of Hop1; functionally redundant with Mec1p; regulates P-body formation induced by replication stress; homolog of human ataxia-telangiectasia mutated (ATM) gene [Source:SGD;Acc:S000000184]) HSP 1 Score: 139.043 bits (349), Expect = 8.771e-33 Identity = 83/266 (31.20%), Postives = 140/266 (52.63%), Query Frame = 1
Query: 7258 PRKLTIIGDDGHNYMFLLKG-HEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEM--LKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVL 8046
P+ +T DG L+KG ++D+RQD Q F +N ++ +++ ++L I+ V+PL G+I +V NS +L+ ++ ++ ++ K M ++ + E+L K I L + + + WFE + + + +A S+VGYILGLGDRH +NI+L +G+ IHID G F+ + PE VPFRLTR ++ VTG++GLFR + ++ ++RK+ ++ VL DPL WV+
Sbjct: 2447 PKIVTFNISDGTTQKALMKGSNDDLRQDAIMEQVFQQVNKVLQNDKVLRNLDLGIRTYKVVPLGPKAGIIEFVANSTSLHQILSKLHTNDKITFDQARKGMKAVQTKSNEERLKAYLK-------ITNEIKPQLRNFFFDSFPDPLDWFEAKKTYTKGVAASSIVGYILGLGDRHLNNILLDCSTGEPIHIDLGIAFDQGKLL-PIPELVPFRLTRDIVDGFGVTGVDGLFRRSCERVYAVLRKDYVKVMCVLNILKWDPLYSWVM 2704
BLAST of Tor vs. Ensembl Yeast
Match: TRA1 (Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation [Source:SGD;Acc:S000001141]) HSP 1 Score: 65.0846 bits (157), Expect = 2.092e-10 Identity = 100/435 (22.99%), Postives = 168/435 (38.62%), Query Frame = 1
Query: 7054 WEIYSNLYRKWSKQISN----VSTLE-LSVASPRLHDYNDWI---LAIPGSY----DPNRPIVKINSIKNCLNLMTSKQHP-RKLTIIGDDG--HNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQV-----------LLNREHKEMLKIAPDFEKLNIIQKTEVFES----GIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYP-------------------------EKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSANIDAINELRKALQL-HVNPNNVPTTSVQF 8190
+E Y R W +++ N S E L V P L +++ + IPG Y D N +KI ++ + R+L I G DG H++ R++ER Q + L N + N +T R ++ IPLS ++ + TL+ + ++ +K LN H + L APD I K E+F S + + KD H L + + W R+ F + + Y++ + +R P I + + SG V F + + ++P E VPFRLT + + + +EG+F I + + L L F+ D ++ W N + + + + N+D I +RK QL H+ N+ PT + QF
Sbjct: 3307 YETYIKRLRYWRRRLENKLDRASKKENLEVLCPHLSNFHHQKFEDIEIPGQYLLNKDNNVHFIKIARFLPTVDFVRGTHSSYRRLMIRGHDGSVHSFAVQYPAVRHSRREERMFQLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEIHNEFCKKKGFDPDDIQDFMADKLNAAHDDALP-APDM----TILKVEIFNSIQTMFVPSNVLKD--HFTSLFTQFEDFWLFRK-QFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNV--------FTLEMLPSRFPYERVKPLLKNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNELNTYLALFIRDEIISWF--SNLHRPIIENPQLREMVQTNVDLI--IRKVAQLGHL--NSTPTVTTQF 3719
BLAST of Tor vs. Ensembl Nematostella
Match: EDO44977 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU99]) HSP 1 Score: 822.002 bits (2122), Expect = 0.000e+0 Identity = 527/1605 (32.83%), Postives = 878/1605 (54.70%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTIHAIPRLAALE---VPSQYIKQSLDFLHRCIKK--EKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGA-----NDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSV-NDVGLVVSMHET---IEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLV--DALEGSVRS-ILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSV--------NLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLE-SILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQN-ILFDLLTINNKLQLEEAASGVVLYATKVY-RDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRI-LLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNR 5949
S+ C++ + K + + +++ ++ + Q + +PRLAA + +Y+K+S+ +L +K+ E+ ++ +G +A E F + + +K +LP +D+ K+++ + ++ ++ + +++ K+ +KE++ M+ VGLS L L ++ +P+L I LLK L LM P + + + L+P +++ D + + ++ALRTL FDF+ H L+ V + + +F+ +K++R+EAV+TC++LL+P L G S +T V++VL K+L+V +DP+ D+R CV S DERFDA+LAQ +L+ LFVA DE FEIR++ I + RLS +NP+ + P+LRK L+Q LTELE+SG R+KEQ+A++L L+ AP +++ P ++ I+ A +IP R ++V ++V+ AI A V G+K+ K + +L P +I M+QD++S+ KR +A+ TL +LV TGYVVEPYRK+P LL +LL L+TE+ IRRE I++LG +GALDP+K K ++++ V +D G+ E+ + VD S +E+LV +L++FY A + +L +++RDP+ S++ + + IFK LG V YL Q++P + I D+ ++ QL ++ +VK H++ ++ + ++ + W + + + L++ + + LG + K +L ++ + + ++ + SV + +L L F S+++++H+L+P ++K+ + L ++K AL+ L RL+E+LDL+D A RI+ P+ R LD +EL A D L++L+ ++ +R+ P + K L IK+ + R++ + K++K +++ + E++L RR++L N D S T+ E S+ +LQKAW A + +S DDW++WL+ S+ L KESPS A+RS L++ LFNA+FVSCW EL + Q+ L+ LE ++ ++ P E++Q +LNL EF+ H E+ LP+++ L +A K R YAKAL+YKE+EF P L L++INNKLQ EAA GV++YA +++ D+++ ERW+E L DW ALN Y++KL D D + LTLGRMRC++ALG+W L + D++ V D I+ +MA + AAW LG++ +M +Y IP + EG F RA +A+ H+ F +A I ARD LD+ LTA AGESY RAYG +V Q L+ELEE+IQYKLV E +E I++ W +RL+GCQ+V++DW+++LQ+RSLVLTP +DM +WLK++ L R+S RL +S + L GS+ SK + L +PQ+ F++ K+ W GQ + A +L V L + + ++ D+ + + L+A+C L+LGDW + + N +I+ Y ATE +AW +WA N+ + KN+
Sbjct: 330 SKVCKEFMEDKFDEVCILVLYYSGTRNSTIQQTLLTLLPRLAAFQPQKFVKKYLKESMQYLVGALKRDRERSSAFKAIGLLAIAVRHNIEP--FSKPVVEQVKQSLPMRDLGHKRQKAVTVDPMVFACVAMLSRAIGPKISKDVKELLEPMLSVGLSPALTACLHDLAHQVPQLKKSIQDGLLKMLSLILMQKPLRHPGAPKSTPA-------------LTPSTSSHSLFDSSDVTSTVLALRTLGSFDFEGHLLT-HVNLVRNCAETFLASEFKDIRMEAVRTCSRLLSPSLHPMVVTNAPQHGPISATST-QVVSEVLSKMLMVGITDPDPDIRHCVLSSLDERFDAHLAQAENLAALFVALNDEEFEIREVAISIISRLSNLNPAYIMPSLRKALIQILTELEYSGVGRSKEQSARMLGHLVSNAP-----------MLIRPYMEPILKA--------------------------------LIPKLRDPDPEVV----------------ISVLAAIGEHAQVSGTKMCKWMNELFPIIIDMLQDASSMAKRKIALWTLGQLVESTGYVVEPYRKYPNLLEVLLNFLKTEQAPGIRREAIRVLGLLGALDPYKHK--LNQIEGVLDDGGISTGSKESETAVCDDRVDTSTSEMLVTMGSVVLEEFYPAVVISALMRIVRDPSLSSHHTMVIQAVTFIFKSLGMKCVTYLSQIMPSFLNVIRTC-DSGFREFVFQQLGVLISIVKQHIRNYLDDIFTLIKEYWTINSPMQTTIVLLVEQIAVALGGEFKNYLPQIIPHILKVFMHDNSPQRSVTTKLLNALQMFGSSLDDYLHLLVPPVVKLFDSNEI--PLSVRKCALETLDRLSESLDLTDFASRIIHPIVRTLD---------------------------SCSELRGTAMDTLSSLVFQLGKRYSTFIPTVNKVL--IKH--------KIQHQRYDVLICKIVKSNFVLDWENDL-----LLRRQKLVRG-----NFADDSATTAAIEAASIKKLAFKPDSLQKAWGASRCVSKDDWMEWLRRLSVELLKESPSPALRSSWATAQTYPPLARDLFNAAFVSCWSELHEELQNELVKNLELALKSQIP--EITQTLLNLAEFLEHTEKGALPLSSDLLGEQASKCRAYAKALHYKEEEF-------HRVPNTETLEALISINNKLQQPEAAHGVLVYAQRMHGADEIR--ERWYEKLHDWENALNAYKKKL-DQDPEDIH---LTLGRMRCMEALGEWGELHTVACDKWPDVSDDIRKQMARMAAAAAWGLGNWESMEEYTCLIPRDTQEGAFYRAALALHHDNFQQAQACIDAARDLLDTELTARAGESYNRAYGAMVSVQMLSELEEIIQYKLVHERREDIKRTWWNRLQGCQRVVEDWQKILQVRSLVLTPQEDMQSWLKYSSLCRKSGRLALSHKTLVMLLGSDPSK-HPDLPLPTTYPQVTFAYMKHLWREGQKEEAFQHLHFFVHTTLHQ------QALQSLSPNDDDNKREELLKLVARCYLKLGDWQS-----SLQGFNENTIPQILLYYSAATENDKSCYKAWHSWAFMNFEAVLYYKNQ 1779 HSP 2 Score: 643.654 bits (1659), Expect = 0.000e+0 Identity = 308/599 (51.42%), Postives = 429/599 (71.62%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNT------KKGGENTV-----ETDDSLSANIDAINELRKALQLH 8151
Y+ PAV GF +I+LS +LQD+LRL+ L F + H+ + E + +G+ I ++ WL VI QL+ARIDT ++ V +I LL +G+ HPQA++ PL +A KS S R AN+IL +M HS +LV +A +++EELIR+ I W E+W E LE+ASR+++ E N MF +L PLH +MER +T E +F Y DL A+ C RY+ S DLTQAW++Y ++R+ SKQ+ +++LEL SP+L D LA+PG+Y+P++P++ I ++ + LN++TSKQ PRKL + G +G ++MFLLKGHED+RQDER MQ FGL+NTL+ S+ +TS+ +LSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML +APD++ L ++QK EVFE + ++G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGY+LGLGDRHPSN+ML R +G+++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTGI+G +R T ++ MR++++S++AVLEAF++DPLL W L DN KG +T+ E + + N D + + A LH
Sbjct: 1809 YAKPAVHGFFKSIALSSGNSLQDTLRLLTLWFDYGHLPEVYEALVEGIKTIQIDTWLQVIPQLIARIDTPRQLVGRLIHQLLTDIGKHHPQALIYPLTVASKSASSARHN-AANQILKNMCEHSQQLVQQAVMVSEELIRVAILWHELWHEGLEEASRMYFGEGNVKGMFAVLDPLHQMMERGPQTLKETSFNQAYGRDLMEAQEWCRRYQKSGNVKDLTQAWDLYYTVFRRISKQLPQLTSLELQYVSPKLLMSRDLELAVPGTYEPHKPVIHIRNVHSSLNVITSKQRPRKLCLAGSNGSDFMFLLKGHEDLRQDERVMQLFGLVNTLLASDPETSKRHLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLTMAPDYDHLTLMQKVEVFEHALANTNGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYVLGLGDRHPSNLMLDRLTGRILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGIDGNYRLTCESVMRTMREHKDSVMAVLEAFVYDPLLNWRLMDNAAPKIKRSKGRSDTMTEAAEEMLEGVDVNRDKPSAKKPAEPLH 2406 HSP 3 Score: 83.5741 bits (205), Expect = 1.427e-15 Identity = 52/202 (25.74%), Postives = 112/202 (55.45%), Query Frame = 1
Query: 106 FLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
L+GLK++SDE +L+ AK+ +++V+ EL++ S E+ +F+D+ M+ S+D NE+K ++ + ++ + S + S+ + ++++ +ND + + ++ + + L + + VE ++K + + D ++EG+R A L+ +E++ A T FFQ +++ +RD + ++RE AL + A RE
Sbjct: 8 LLSGLKSRSDESRLQAAKDLQHYVSTELREASPEQYGSFMDEFNHHIFEMVSSSDANEKKGGIMAIVGLIGISG-GSATKVSRFANYLRNLLPSNDTAVMEMASKAMGRLALTGGTFTADYVEFEVKRALEWLGGD-RNEGRRHAAVLVLRELAVNAPTFFFQQVQPFFDNIFNAVRDPKQAIREGAMEALRACLVILAQRE 207 HSP 4 Score: 62.3882 bits (150), Expect = 3.716e-9 Identity = 35/118 (29.66%), Postives = 58/118 (49.15%), Query Frame = 1
Query: 8353 WFGCYNTALKMRKRATDGSIIVE--RNGLEGLIFSAKSPISDRPNY------DDTEDEWAGANMRAMDVMKHIKNKLEGKEVGG--NLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
W N A K+++ + E LEG+ + P + +P ++T + N +A+D++ +++KL G++ L VD+L+KQAT + NLCQ Y GWC FW
Sbjct: 2358 WRLMDNAAPKIKRSKGRSDTMTEAAEEMLEGVDVNRDKPSAKKPAEPLHSIEEETGHKPEFLNKKALDIITRVRDKLTGRDFANRNTLDVPTQVDLLIKQATAHENLCQCYIGWCPFW 2475
BLAST of Tor vs. Ensembl Nematostella
Match: EDO48437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJW4]) HSP 1 Score: 206.453 bits (524), Expect = 6.888e-53 Identity = 148/506 (29.25%), Postives = 241/506 (47.63%), Query Frame = 1
Query: 6733 ILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECL----EDASRLHYE------------------------EKNTTAMFKILYPLHILME---REIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVA--SPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQR-MSVIPLSTNTGLIGWVPNSDTLNAVIRDYREK---TQVLLNREH------------KEML--KIAPDFEKLNIIQKTE-------------VFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNT 8058
I+ S++ + +LV+E +EL R+ + W E+W L +D R + EK+ M I++ L L + ++ T HE F+ Y + A L +N +D +W+ + L + + S L + SP L + +PG IV I+++ N +N++ +K P+KL +G DG + +L KG ED+ DER MQF + N M + + R L R SV PL +GLI WV + + A+ + ++++ T LL E+ K+ P ++ I+ E V E I E+ L+ LW S + W+ + RS AVMSM+GYI+GLGDRH N+++ +G+V+HID+ CFE + PEKVPFR+T L A+ VTG+EG+FR + Q++ ++++ RE+LL +LEAF++DPL+ W +++
Sbjct: 228 IVSSLQSLNPKLVTELQGFIQELRRITLLWEELWLGSLIQTHQDVVRRQQQLDEEIKRVNSNVNLTDGQRAALIREKHVAIMRPIVFALEQLQKITNQQACTPHEQWFHRAYSALIEKA--LASLTNPAN-PSDARSSWDPFKQLLQTLQGRSMKKSAYSLVMEDISPTLAKMKSTAIYMPGQSHFEGEIVSISAVVNEVNILPTKTKPKKLVFVGSDGQRHTYLFKGLEDLHLDERIMQFLSICNN-MFTRADSHRCPLFCARHYSVTPLGPRSGLIQWVDGAVPVFALYKRWQQREAATNALLKSAQGSNQPPPPPMKPSELFYSKMTPALKEKGIVDPKESGRKEWPIAVMRQVLEELIAETPSDLLSRELWCSSTGALEWWHMTKTYARSTAVMSMIGYIIGLGDRHLDNMLIDFTTGEVVHIDYNVCFEKGRGL-RVPEKVPFRMTPNLEMALGVTGVEGMFRLSCEQVLKILKQGRETLLTLLEAFVYDPLVDWTTANDS 728
BLAST of Tor vs. Ensembl Nematostella
Match: EDO36404 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIS1]) HSP 1 Score: 167.933 bits (424), Expect = 3.249e-41 Identity = 100/313 (31.95%), Postives = 156/313 (49.84%), Query Frame = 1
Query: 7201 IVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDS---LSANIDAINEL 8130
IV ++ +L P+ + +G DG L+KG +D+RQD Q FG++N L+ +N +T + L ++ VIPLS +G++ W + L + R + K+ + + + GI + H K + WFERR + RS A S+VGYI+GLGDRH NI++ +S +++HID G FE + PE VPFRLTR L+ M VTG+EG+FR + + +MR ++E+L+ +LE L+DPL W L K + T +D S +D + +L
Sbjct: 1345 IVYVDRFMPTFSLAGGVNLPKIIACVGSDGVKRRQLVKGRDDLRQDAVMEQVFGMVNQLLANNTETRKRKLRVRTYKVIPLSQRSGMLEWCEGTMPLGEYLIGSPGHNTGAHQRYNPRDWSPMDCRRKMASVVRNYIL-IGIMDHFKPVFRHFFLEKFVDPAEWFERRLAYTRSCATSSIVGYIVGLGDRHVQNILVDCNSAELVHIDLGVAFEQGKVLPT-PETVPFRLTRDLVDGMGVTGVEGVFRRCCEKTMAVMRTSQEALVTILEVLLYDPLYSWTLSPEKKMALQATKPDNDVSEISSTAVDLVGDL 1655
BLAST of Tor vs. Ensembl Nematostella
Match: EDO34280 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPT8]) HSP 1 Score: 164.851 bits (416), Expect = 3.212e-40 Identity = 113/360 (31.39%), Postives = 184/360 (51.11%), Query Frame = 1
Query: 7063 YSNLYRKWSKQISNVS--TLELS---VASP--RLHDYNDWI-----------LAIPGSYD-PNRPI----VKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIR---DYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILW--LK------SHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
+ N++ K +++ N+S T +L V+ P L +Y+ W+ L +PG Y ++P+ V I + ++ S + P+++TI GDD ++MFL+KG EDIR D+R Q F ++N +M + S+ NL ++ VIP++ GLI W+ N+ L ++ EK +++ R+ K ML + +II E + K A + W L+ + + EA+ RT+F R+ A + + Y+LG+GDRH SN ++ +G +I IDFG F AT PE VPFRLTR + GL R+T I ++ +R N E LL ++ F+ +P L W
Sbjct: 1388 FENIFGKDGEKLVNMSLKTAKLKQQMVSKPPGNLKEYSPWLTNFQADSHAQKLEVPGQYTGQSKPMPEYHVNIAGFDEKVLVLASIRKPKRVTIRGDDERDHMFLVKGGEDIRLDQRIEQLFCMMNEVMSEDPACSQRNLRLRTYQVIPMTQRVGLIEWLKNTKPLKELLHIAATESEKQAMVVRRKTKNMLDLTLRI-LFDIIISREANRTDTESEFKKKQAQVPWDLLRRAFQQLAASPEAYLTLRTHFARTHACICICQYVLGIGDRHLSNFLVDMRTGGLIGIDFGHSFGSATQFLPVPELVPFRLTRQFTNLLLPLKESGLVRNTMIHVMRALRGNHELLLNTMDVFVKEPSLDW 1746
BLAST of Tor vs. Ensembl Nematostella
Match: EDO29217 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T497]) HSP 1 Score: 119.398 bits (298), Expect = 6.115e-30 Identity = 63/157 (40.13%), Postives = 90/157 (57.32%), Query Frame = 1
Query: 7675 HNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSANIDAINELRKALQ 8145
N +W+E R + R+ AVMSMVGYILGLGDRH NI+ +G+ +H+D F + PE+VPFRLT L+ AM + G EG++R + + LMR +SLL VL F+HDPL++W+ T G+ + D N +A+ L+ Q
Sbjct: 15 QNPTSWYESRLAYCRTTAVMSMVGYILGLGDRHGENILFDSTNGECVHVDLNCLFNKGETFD-CPERVPFRLTHNLVDAMGLLGYEGVYRRSCEVTLRLMRSQCDSLLTVLGTFIHDPLMEWLRPRGTP--GDPSKSKDTGEVTNEEAVKILKSIEQ 168
BLAST of Tor vs. Ensembl Medaka
Match: mtor (mechanistic target of rapamycin kinase [Source:ZFIN;Acc:ZDB-GENE-030131-2974]) HSP 1 Score: 647.506 bits (1669), Expect = 0.000e+0 Identity = 311/574 (54.18%), Postives = 420/574 (73.17%), Query Frame = 1
Query: 6388 YSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSAN 8109
Y+ PAV+GF +ISLS NLQD+LR++ L F + H + E + +G+ I ++ WL VI QL+ARIDT + V +I LL +G HPQA++ PL +A KS + R ANKIL +M H LV +A +++EELIR+ I W EMW E LE+ASRL++ E+N MF +L PLH +MER +T E +F Y DL A++ C +Y S DLTQAW++Y +++R+ SKQ+ +++LEL SP+L D LA+PG+YDPN+PI++I SI L ++TSKQ PRKLTI+G +GH +MFLLKGHED+RQDER MQ FGL+NTL+ ++ + R NLSIQR +VIPLSTN+GLIGWVP+ DTL+A+IRDYREK ++LLN EH+ ML++APD++ L +++K EVFE + + G DLA +LWLKS +SE WF+RRTN+ RSLAVMSMVGYILGLGDRHPSN+ML R SGK++HIDFGDCFEVA REK+PEK+PFRLTRML AMEVTG++G +R T ++ ++R++R+S++AVLEAF++DPLL W L D+ KG + + DS +A
Sbjct: 68 YTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPEVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHN-AANKILKNMCEHCNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMRSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAASLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMEKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDSNTKGTKRSRTRTDSYTAG 640 HSP 2 Score: 55.4546 bits (132), Expect = 9.755e-7 Identity = 22/56 (39.29%), Postives = 37/56 (66.07%), Query Frame = 1
Query: 8515 NMRAMDVMKHIKNKLEGKEVGGNLTSE--EHVDMLVKQATCNYNLCQMYFGWCAFW 8676
N +A+ ++ +++KL G++ + T + V++L+KQAT + NLCQ Y GWC FW
Sbjct: 682 NKKAIQIINRVRDKLTGRDFSHDETLDVPTQVELLIKQATSHENLCQCYIGWCPFW 737
BLAST of Tor vs. Ensembl Medaka
Match: mtor (mechanistic target of rapamycin kinase [Source:ZFIN;Acc:ZDB-GENE-030131-2974]) HSP 1 Score: 375.555 bits (963), Expect = 1.090e-108 Identity = 251/716 (35.06%), Postives = 382/716 (53.35%), Query Frame = 1
Query: 1225 SQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTI-HAIPRLAALE---VPSQYIKQSLDFLHRCIKKEKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPL-LEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLS--VDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCI 3351
S+ CR+L+ + + + + +++ K+P LIQ+TI + +PRLAA + QY+ S+ L C+KKEK + + E +L K + IK LP KD + K+++ + ++ +++ I +++ + IKE++ M+ VGLS L L +S IP+L DI LLK L LM+ P + GL + + +L+ + + +ALRTL F+F+ H+L+ FVR + F+ +KE+R+EA +TC++LLTP + N G + + VADVL KLL+V +DP+ D+R CV S DERFDA+LAQ +L LFVA DE+FEIR+L I +GRLS++NP+ + P LRK+L+Q LTELE SG RNKEQ+A++L L+ AP ++ + E +L L+ +++ PD NP AV ++V+ I LA V G ++RK + +L P ++ M+QDS+SL KR VA+ TL + V TGYVVEPYRK+P LL +LL L+TE+ IRRE I++LG +GALDP+K K +D D V + D S +E+LVN LD+FY A A+ +L ++LRDP+ +++ + + IFK LG VQ+L QV+P + I
Sbjct: 358 SRYCRELMEERFDQVCRWVLKYKTSKNP-LIQMTILNLLPRLAAFQPHNFTDQYLSDSMGHLLGCLKKEKERTAAFQALGLLVVAVRTEIQPYLSKILEIIKAALPPKDFAHKRQKTIQVDATVFTCISMLSRAMGPSIQPDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPG---------------MPKGLAHQMASPSLTNIPEAGDVGGITLALRTLGSFEFEGHSLTQFVRHCADH---FLNSEHKEIRMEAARTCSRLLTPSI--NLINGHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDEVFEIRELAICTIGRLSSMNPAFVMPFLRKMLIQILTELEHSGVGRNKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKD--------PD--------------------------------------------PNP-----AVVISVLATIGELAQVSGLEMRKWMDELFPIIMDMLQDSSSLAKRQVALWTLGQQVASTGYVVEPYRKYPSLLEVLLNFLKTEQNQGIRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSADYSTSEMLVNMGNLPLDEFYPAVAIVTLMRILRDPSLSNHHTMVVQAVTFIFKSLGLKCVQFLPQVMPTFLNVI 995 HSP 2 Score: 78.5666 bits (192), Expect = 9.274e-14 Identity = 46/202 (22.77%), Postives = 114/202 (56.44%), Query Frame = 1
Query: 106 FLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLIS---SPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAARE 702
F++GLK+++++ + K+AK+ +++V EL++ S +E TF D++ ++ S+D+NE+K ++ + ++ ++ + + S+ + ++++ ++D + + ++ + ++ + E VE ++K + + D ++EG+R A L+ +E++ A T FFQ +++ + D++ ++RE AL +T RE
Sbjct: 24 FVSGLKSRNEDTRAKSAKDLQHYVTTELRELSQDEATTFYDELNHHIFELVSSSDVNEKKGGILAIVSLIGVEG-GNATRISRFANYLRNLLPSSDPVVMEMASKAMGHLSMAGDTFTAEYVEFEVKRALEWLGAD-RNEGRRHAAVLVLRELAVSAPTFFFQQVQPFFDNIFYAVWDQKQAIREGAVSALRACLILTTQRE 223
BLAST of Tor vs. Ensembl Medaka
Match: atr (ATR serine/threonine kinase [Source:NCBI gene;Acc:101157099]) HSP 1 Score: 166.777 bits (421), Expect = 2.368e-40 Identity = 100/278 (35.97%), Postives = 157/278 (56.47%), Query Frame = 1
Query: 7231 LNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEML--KIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDF------GDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
+ ++ S Q P+K+++ G DG +Y + K +D+R+D R M+F LIN + + ++ R L I+ +VIPL+ G+I WV N+ L ++ ++ L +E ++++ K AP EKL I ++ + + + H +L++ R+ + RS AVMSMVGY+LGLGDRH NI+ +G+ +H+DF G+ F+V PE VPFRLT+ ++ AM G EGLFR + LMR RE L+ VL+ FLHDPL++W
Sbjct: 1825 VEILASLQKPKKISLRGSDGRSYTMMCKPKDDLRKDCRLMEFNCLINKCLRKHAESRRRELHIRTYAVIPLNEECGIIEWVNNTAGLRHILTKLYKERVYLSGKELRKLILPKTAPFEEKLRIHKE-------VLCARHPPVFHEWFLRTFPDPT--SSRSAYCRSTAVMSMVGYVLGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFDV-------PEVVPFRLTQNMVHAMGPMGTEGLFRQACEVTLRLMRDQREPLM-VLKTFLHDPLVEW 2085
BLAST of Tor vs. Ensembl Medaka
Match: prkdc (protein kinase, DNA-activated, catalytic subunit [Source:NCBI gene;Acc:101171206]) HSP 1 Score: 147.132 bits (370), Expect = 2.245e-34 Identity = 107/370 (28.92%), Postives = 179/370 (48.38%), Query Frame = 1
Query: 7129 ASPRLHDYNDWI-----------LAIPGSYDPNRPI-VKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHD--NTKKGG--ENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSVQF 8190
A L +Y+ W+ L +PG P KI + +M+S +HP++L I GDD ++ FL+KG ED+RQD+R Q F ++N ++ ++ + L + VIPL+T GLI W+ N+ TL +D+ KT + E+K + L ++Q DL ++ EA+ R++FI S A++ + +ILG+GDRH SN M+ ++G +I IDFG F AT PE +PFRLT+ + M+ GL + + + R + LL ++ F+ +P L W + +KGG ++V T + + +N R+ L+ NP + + ++
Sbjct: 3550 APGNLKEYSPWLSGFKADSFSNELEVPGRSKPLPEYHAKITGFDERVMVMSSMRHPKRLIIRGDDERDHPFLVKGGEDLRQDQRIEQLFSIMNIVLSNDTACVQRGLQLHTYQVIPLTT-VGLIEWMENTCTL----KDFVYKT--MTEEENKRAKRADAVNNFLKVLQHVPA-----------DLLRSFLRMCNSPEAFLSLRSHFISSHALLCVSHWILGIGDRHLSNFMVNVETGGMIGIDFGHAFGSATQFLPVPELMPFRLTQQFVNLMQPLKESGLIQSIMVHSLRAYRAEPDLLLNTMDVFIKEPCLDWKNFEVKQLRKGGTWTDSVNTKEVNWYPLQKVNFARRKLE-GANPAAITSEELKL 3900
BLAST of Tor vs. Ensembl Medaka
Match: pik3c2a (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [Source:NCBI gene;Acc:101155105]) HSP 1 Score: 78.5666 bits (192), Expect = 1.204e-13 Identity = 75/270 (27.78%), Postives = 116/270 (42.96%), Query Frame = 1
Query: 7201 IVKINSIKNCLNLMTSKQHPRKLTIIGDD--GHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHN-SEAWFERRT-NFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYP-EKVPFRLTR----MLIGAMEVTGIEGLFRHTSIQIVNLMRKN 7983
+ K +IK C + +S P KL ++ D G + K ED+RQD A+Q +++ + + ++L I I + G++ VP+SDTL + +Y G+ S KD WL+ +N +E +E+ + NFI S A + Y+LG+ DRH NIML R +G + HIDFG A M + ++ PF LT ++ G T LF Q NL+RK+
Sbjct: 1058 VAKELNIKAC-SFFSSNAVPLKLALVNADPLGEEINVMFKVGEDLRQDMLALQMIRIMDRMWLQEG----LDLRIVNFKCISTGKDKGMVELVPSSDTLRKIQVEY------------------------------------GVTGS-FKDKPLAEWLRKYNPAEDEYEKASENFIYSCAGCCVATYVLGICDRHNDNIML-RSTGHMFHIDFGKFLGHAQMFGSFKRDRAPFVLTSDMAYVINGGERPTSRFQLFVDLCCQAYNLIRKH 1284
BLAST of Tor vs. Planmine SMEST
Match: SMESG000025384.1 (SMESG000025384.1) HSP 1 Score: 5841.54 bits (15153), Expect = 0.000e+0 Identity = 2860/2866 (99.79%), Postives = 2862/2866 (99.86%), Query Frame = 1
Query: 79 MTPIDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLISSPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAAREGIGRRRQKVINDTTNQNTASSKLPMVSLGSSQFQKQISQQPVNQLRANDSGILESGKIHIEQDWSQELYSNCIAELLRTLXXXXXXXHINSRKLNQESWSHGTXXXXXXXXXXSNDEMEMNRIQLERMIGLSLDQLSSSPMPSGVLSARAICRMEWPYSKMEEHIIQHRSKIHLSQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTIHAIPRLAALEVPSQYIKQSLDFLHRCIKKEKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSIENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPEXXXXXXXXXXTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLVDALEGSVRSILELLPEFEYSIEEHVHXXXXXXXXXXXXENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLAELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDTSQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLAKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNRIVELTRQMSVIARRWKQLQHQEVTDTRRSSLTQGFNTNSQIVNQNNGSTVMSSEVARISQPQLRFSLLQSQQKRGCNLVSFPSTVPHVPESLATFGQAVAVRQPDNENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSVQFTNVPRNHSSRPSSGNIPHMPDNIRIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPWFGCYNTALKMRKRATDGSIIVERNGLEGLIFSAKSPISDRPNYDDTEDEWAGANMRAMDVMKHIKNKLEGKEVGGNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 8676
MTPIDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMI FVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLISSPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAAREGIGRRRQKVINDTTNQNTASSKLPMVSLG+SQFQKQISQQPVNQLRANDSGILESGKIHIEQDWSQELYSNCIAELLRTLDDSSSSSHINSRKLNQESWSHGTLLLLNELLKLSNDEMEMNRIQLERMIGLSLDQLSSSPMPSGVLSARAICRMEWPYSKMEEHIIQHRSKIHLSQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTIHAIPRLAALEVPSQYIKQSLDFLHRCIKKEKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKS ENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPELLRLLLMMLRTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLVDALEGSVRSILELLPEFEYSIEEHVHILLPSIIKIISKENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQL+ELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILD SQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISL KESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNRIVELTRQMSVIARRWKQLQHQEVTDTRRSSLTQGFNTNSQIVNQNNGSTVMSSEVARISQPQLRFSLLQSQQKRGCNLVSFPSTVPHVPESLATFGQAVAVRQPDNENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSVQFTNVPRNHSSRPSSGNIPHMPDNIRIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPWFGCYNTALKMRKRATDGSIIVERNGLEGLIFSAKSPISDRPNYDDTEDEWAGANMRAMDVMKHIKNKLEGKEVGGNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW
Sbjct: 1 MTPIDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMIIFVDKIYSEFISMIESNDINERKAVLICMGCIVDLDFIFSHSNFSKLSLLIQDMPITNDIQISALQARLIAQFNLISSPEKVESQIKESCSVVVDDSKSEGQRIYAALLFKEISFYASTVFFQFASRVINSLLIGIRDKQASVREVCAIALANAFAVTAAREGIGRRRQKVINDTTNQNTASSKLPMVSLGNSQFQKQISQQPVNQLRANDSGILESGKIHIEQDWSQELYSNCIAELLRTLDDSSSSSHINSRKLNQESWSHGTLLLLNELLKLSNDEMEMNRIQLERMIGLSLDQLSSSPMPSGVLSARAICRMEWPYSKMEEHIIQHRSKIHLSQSCRKLIMAKLEFIWQMLIQNFDWKHPYLIQLTIHAIPRLAALEVPSQYIKQSLDFLHRCIKKEKPLSYITMGFIAHIAPGEFEKNEFLEKTITAIKLNLPGKDISTKKRQPLLEVSIYMLIGLIATGFKNKVHVVIKEMIGTMVEVGLSFPLIYSLKMVSLFIPELTNDIHGTLLKSLRKTLMNNSRTEPKKAQYSTSISLENETLLCNGLLSPLVAANLSVDQIEARNKIIALRTLVEFDFDKHNLSLFVRFISSKLISFITCSYKEVRLEAVKTCAQLLTPLLGANDDEGSFSDRNTLTAVADVLEKLLIVSTSDPERDVRLCVFQSFDERFDAYLAQECHLSPLFVAFYDEMFEIRKLVIRCLGRLSAINPSCLKPNLRKILLQTLTELEFSGSSRNKEQAAQILAELIDTAPGFVQSHSEKLLLVLLPRIQSIICAAKSQPDGKSTENFNVKATHIIGKGYKISTSSIMIPIYRKGSIDIVDNLVATNPIVEPTAVQLAVIQAIKNLAVVCGSKLRKHLGDLVPALIYMMQDSTSLDKRFVAVTTLSKLVTHTGYVVEPYRKHPELLRLLLMMLRTEEVGSIRREVIKLLGTIGALDPFKQKKFCSELDSVNDVGLVVSMHETIEKKEVDMSQAELLVNTQWKILDDFYTACALQSLTQLLRDPTYRSNYDRICMVIISIFKYLGPNSVQYLKQVLPEYFRCIMEAQDNRHQQTFLSQLCIITDVVKLHLKQFMPQLIEILLQLWNKSDKLTLVCIQLLKSLNIGLGADIKPFLSPLMGVFQQTLVDALEGSVRSILELLPEFEYSIEEHVHILLPSIIKIISKENLGSTLQIKKAALDCLTRLAETLDLSDSAGRIVQPVCRLLDFSEPSTAYTTQLSSSLQGVATTNLSNEQLSELIPPAFDLLTTLLVKMRRRFMVLTPLIQKTLENIKYHFPAGTTQSMSFARFNTALNKVLKISYISNHEDNLDQFESFARRKRLENSSTYVPNILDISQTSMTQEINSVNLQKAWAAKKMISSDDWIQWLKNFSISLVKESPSNAIRSCSNLGGCTGVLSKALFNASFVSCWPELTDTQQDNLIATLESILNECPSTEVSQAVLNLEEFMTHCERMKLPIATSALASRALKNRVYAKALYYKEQEFLEETAKKGSAPQNILFDLLTINNKLQLEEAASGVVLYATKVYRDKLQNEERWHEILQDWTKALNLYQRKLEDNDSRRVQNNELTLGRMRCLQALGDWSSLKNIGIDRFDQVDDSIKTKMAPIIVNAAWALGDFNTMNKYVESIPLNNFEGPFLRAVIAIQHEEFHEASEYIQKARDELDSCLTAMAGESYIRAYGDLVEAQKLAELEEVIQYKLVRESQETIRQAWIDRLKGCQQVIDDWRQLLQIRSLVLTPNQDMTTWLKFAGLARRSNRLEMSKSIMDRLYGSELSKISKNNILNCQFPQIIFSWSKYQWTTGQHQMALGNLELLVEQKLKNDIIIMTERINNIQIVDESCVKNSRILLAKCALRLGDWYTESLAKETDALHHNLQYRIVSTYRIATEEAPGTKRAWQAWAMANYAIICMSKNRIVELTRQMSVIARRWKQLQHQEVTDTRRSSLTQGFNTNSQIVNQNNGSTVMSSEVARISQPQLRFSLLQSQQKRGCNLVSFPSTVPHVPESLATFGQAVAVRQPDNENLSTATIESNDSPNDLIMLENQYRLLDKQRKALIVEREAYSHPAVRGFVNAISLSPTANLQDSLRLVILLFQFDHISRIREVICDGLSKISLENWLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEVHSARLVSEAFLLNEELIRLGISWMEMWTECLEDASRLHYEEKNTTAMFKILYPLHILMEREIETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAWEIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVLHDNTKKGGENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSVQFTNVPRNHSSRPSSGNIPHMPDNIRIFTDNNYPDSKTLRNPYSVNQWRHHLCNGPWFGCYNTALKMRKRATDGSIIVERNGLEGLIFSAKSPISDRPNYDDTEDEWAGANMRAMDVMKHIKNKLEGKEVGGNLTSEEHVDMLVKQATCNYNLCQMYFGWCAFW 2866
BLAST of Tor vs. Planmine SMEST
Match: SMESG000061710.1 (SMESG000061710.1) HSP 1 Score: 164.081 bits (414), Expect = 1.257e-39 Identity = 109/379 (28.76%), Postives = 193/379 (50.92%), Query Frame = 1
Query: 7027 NYKTDLTQAWEIYSNLYRKWSKQISN-VSTLELSVA--------SPRLHDYN-------------DWILAIPGSYD--PNRPI----VKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRI--NLS-IQRMSVIPLSTNTGLIGWVPNSDTLNAVIRD---------YREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLK-SHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
N++ D T + + N + + +I+N + T +L V+ SP L YN DW L IPG Y+ RP +KI ++ + +M SKQ P+K+ IIGD+ Y FL+K ED+RQD R Q F ++N +M + Q ++ LS I+ +VIP+S + GL+ W+ N+ TL+ R Y++ + + +EK +++ + F+ + DL ++ S E+++ R NFI+ A+ Y+LG+GDRH N ++ ++G +I IDFG F +AT+ PE +PFRLT ++ ++ +G+ G+F T ++ + + + ++++++ FL + +L W
Sbjct: 2683 NFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYHQPDVISKDW-LEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMTKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSDFYRKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKPDVVSTNQKFDENQKLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 3060
BLAST of Tor vs. Planmine SMEST
Match: SMESG000061710.1 (SMESG000061710.1) HSP 1 Score: 163.696 bits (413), Expect = 1.477e-39 Identity = 109/379 (28.76%), Postives = 193/379 (50.92%), Query Frame = 1
Query: 7027 NYKTDLTQAWEIYSNLYRKWSKQISN-VSTLELSVA--------SPRLHDYN-------------DWILAIPGSYD--PNRPI----VKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRI--NLS-IQRMSVIPLSTNTGLIGWVPNSDTLNAVIRD---------YREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLK-SHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 8040
N++ D T + + N + + +I+N + T +L V+ SP L YN DW L IPG Y+ RP +KI ++ + +M SKQ P+K+ IIGD+ Y FL+K ED+RQD R Q F ++N +M + Q ++ LS I+ +VIP+S + GL+ W+ N+ TL+ R Y++ + + +EK +++ + F+ + DL ++ S E+++ R NFI+ A+ Y+LG+GDRH N ++ ++G +I IDFG F +AT+ PE +PFRLT ++ ++ +G+ G+F T ++ + + + ++++++ FL + +L W
Sbjct: 2695 NFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYHQPDVISKDW-LEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMTKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSDFYRKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKPDVVSTNQKFDENQKLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 3072
BLAST of Tor vs. Planmine SMEST
Match: SMESG000009788.1 (SMESG000009788.1) HSP 1 Score: 160.614 bits (405), Expect = 1.341e-38 Identity = 156/637 (24.49%), Postives = 275/637 (43.17%), Query Frame = 1
Query: 6553 WLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEV----HSARLVSEAFLLNEELIRLGISWMEMWT----ECLED----ASRLHYE---------EKNTTAMFKILYPLHI-----LMEREI-------ETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAW------------EIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEML-----------------------------KIAPDFEK--------------LNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVL-----HDNTKKGGENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSV 8184
W VI QL AR+ + + + + LL + + L++ GS N + H ++ ++ +LV E + +EL R+ + W E+W +C ++ A +L E K+ + K+ Y I ++ER ET E F+N + +++S +S N + AW E N+ K + +L+L SP L N ++ +PG N+ ++ SI ++++ +K P+K + +G Y +L KG ED+R DER MQ G+ NT+ + I V PL T GLI V + +L ++ + ++ + + + + K+ P E +NI+ EVF R++ L+ LW S NS W+ NF RS AVM ++G+ LGLGDRH N+++ +G++IHID+ CF+ + K PEKVPFRLT ++ + GLFR + + +++++++S+L +++ F+ DP++ W H + GG+ V + SL ID +++++ +N NN + +
Sbjct: 1749 WTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNC--SKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAEEITSTIE---EIKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGM--NNKSLL---SIDKHISILPTKTKPKKFRFLSTNGKYYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNIL--IEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKG-VSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSL---ID-----KRSVEFIINLNNFQSVFI 2364
BLAST of Tor vs. Planmine SMEST
Match: SMESG000009788.1 (SMESG000009788.1) HSP 1 Score: 160.614 bits (405), Expect = 1.355e-38 Identity = 156/637 (24.49%), Postives = 275/637 (43.17%), Query Frame = 1
Query: 6553 WLLVIQQLLARIDTHKEHVSSIIVGLLITVGERHPQAMVNPLVLAFKSGGSDRRRYNANKILHSMEV----HSARLVSEAFLLNEELIRLGISWMEMWT----ECLED----ASRLHYE---------EKNTTAMFKILYPLHI-----LMEREI-------ETHHEVAFYNEYYGDLSSAKNLCIRYESSNYKTDLTQAW------------EIYSNLYRKWSKQISNVSTLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQVLLNREHKEML-----------------------------KIAPDFEK--------------LNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVL-----HDNTKKGGENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSV 8184
W VI QL AR+ + + + + LL + + L++ GS N + H ++ ++ +LV E + +EL R+ + W E+W +C ++ A +L E K+ + K+ Y I ++ER ET E F+N + +++S +S N + AW E N+ K + +L+L SP L N ++ +PG N+ ++ SI ++++ +K P+K + +G Y +L KG ED+R DER MQ G+ NT+ + I V PL T GLI V + +L ++ + ++ + + + + K+ P E +NI+ EVF R++ L+ LW S NS W+ NF RS AVM ++G+ LGLGDRH N+++ +G++IHID+ CF+ + K PEKVPFRLT ++ + GLFR + + +++++++S+L +++ F+ DP++ W H + GG+ V + SL ID +++++ +N NN + +
Sbjct: 1784 WTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNC--SKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAEEITSTIE---EIKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGM--NNKSLL---SIDKHISILPTKTKPKKFRFLSTNGKYYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNIL--IEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKG-VSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSL---ID-----KRSVEFIINLNNFQSVFI 2399 The following BLAST results are available for this feature:
BLAST of Tor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Tor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Tor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Tor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Tor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Tor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Tor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Tor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Tor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Tor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Tor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Tor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Tor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Tor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30006752 ID=SMED30006752|Name=Tor|organism=Schmidtea mediterranea sexual|type=transcript|length=8786bpback to top protein sequence of SMED30006752-orf-1 >SMED30006752-orf-1 ID=SMED30006752-orf-1|Name=SMED30006752-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2867bp MTPIDYVDYFLAGLKNKSDELKLKTAKEFKNFVANELKDKSHEEMITFVDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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