EED-1

Overview


Name	EED-1 (AFD29604.1)
Smed ID	SMED30006748
Length (bp)	1398

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of EED-1 (SMED30006748) t-SNE clustered cells

Violin plots show distribution of expression levels for EED-1 (SMED30006748) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of EED-1 (SMED30006748) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for EED-1 (SMED30006748) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30006748

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30006748	h1SMcG0004019	SmedASXL_013489	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
parenchyma	SMED30006748	h1SMcG0004019	isotig15566	be_Smed_v2	PMID:22543868 Onal et al., 2012
tail stripe	SMED30006748	h1SMcG0004019	isotig15566	be_Smed_v2	PMID:22543868 Onal et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of EED-1 vs. Ensembl Human
Match: EED (embryonic ectoderm development [Source:HGNC Symbol;Acc:HGNC:3188])

HSP 1 Score: 302.753 bits (774), Expect = 7.347e-98
Identity = 158/400 (39.50%), Postives = 221/400 (55.25%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KPS     IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    + +     IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   82 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDR 439

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Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KPS     IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    + +     IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   82 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDR 439

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BLAST of EED-1 vs. Ensembl Human
Match: EED (embryonic ectoderm development [Source:HGNC Symbol;Acc:HGNC:3188])

HSP 1 Score: 302.368 bits (773), Expect = 6.171e-97
Identity = 158/400 (39.50%), Postives = 221/400 (55.25%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KPS     IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    + +     IRQT F+ D+ IL+  CD   I R+DR
Sbjct:  142 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDR 499

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BLAST of EED-1 vs. Ensembl Human
Match: EED (embryonic ectoderm development [Source:HGNC Symbol;Acc:HGNC:3188])

HSP 1 Score: 288.886 bits (738), Expect = 3.244e-92
Identity = 158/425 (37.18%), Postives = 221/425 (52.00%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSK-------------------------SCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SK                         SCE  +V WKPG +   +         +KPS     IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    + +     IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   82 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGKMEDDI-------DKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDR 464

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BLAST of EED-1 vs. Ensembl Human
Match: EED (embryonic ectoderm development [Source:HGNC Symbol;Acc:HGNC:3188])

HSP 1 Score: 283.493 bits (724), Expect = 6.531e-91
Identity = 142/344 (41.28%), Postives = 198/344 (57.56%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLR 1218
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KPS     IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L 
Sbjct:   82 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE 392

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BLAST of EED-1 vs. Ensembl Celegans
Match: mes-6 (Polycomb protein mes-6 [Source:UniProtKB/Swiss-Prot;Acc:Q9GYS1])

HSP 1 Score: 88.5817 bits (218), Expect = 1.038e-18
Identity = 98/453 (21.63%), Postives = 164/453 (36.20%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDG-------MFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVF----------------------------DTFLQ---------------HFPDFSSNKIHGNYIDCGRWFGGL--VFSKSC--EGYLVLWKPGSLNSSLLPTFKIGQDVKP----SILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            F  TA + E    +I+G + N     ++   +   +VGG  +  Y   +D  INNI+                  WS   P    ++  R+         +++Y          V   G  G I +I      +   L   G  IN+I   P   +L+   S D +IR+ ++ N   + + GG E H   IL  D    G F+LSCG DH +  W L   ++   + ++ K LH +   V                             D  L+               + P   S  +H +Y+DC R+  G     SK C  E  +  W+ G     +      G  ++P    +      +     W+++F +D +R  L  G   G +  ++LR+ + T       +  +            T+RQ  F+   + L+   D G + RFDR
Sbjct:   27 FVLTAKLLEDQKKAIYGCAFNQYAGIDEEQAV--ATVGGSFLHMYSVPID--INNIEL----------------QWSCNFPTDKSSKVEREESLFTVTWCYDTYEAENDRNPFKVVTGGTLGHIYVIDYVSRKLSNRLRSVGWEINDIRTCPANSNLIVCASSDQSIRIHHIRNEACLIVIGGLECHAGTILSVDWSTDGDFILSCGFDHQLMEWDLSVKQVKEHLERACKALHQDKINVLTQSQDIPYVSKGTMRKSAVSRNIPDKEEDQLLELHRELIPRPSCLLPIYTPSSVSTDMHSDYVDCIRFLIGTNYALSKGCGNEKAIHFWRFGPPKGEVENRIH-GNVLRPKSCTTKFRTMNVPSGSAWFIKFAVDPRRRWLVCGGAGGSVMFFDLRNNEETNPTHTCSVGSR------------TVRQASFSTCGRFLVLVTDEGFVCRFDR 446

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BLAST of EED-1 vs. Ensembl Celegans
Match: wdr-23 (DDB1- and CUL4-associated factor 11 homolog [Source:UniProtKB/Swiss-Prot;Acc:P90794])

HSP 1 Score: 51.9878 bits (123), Expect = 7.290e-7
Identity = 28/102 (27.45%), Postives = 48/102 (47.06%), Query Frame = 1

Query:  592 LGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWN--VWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHEN 891
            +  H   +N + F  L  +L++S   D  +++W+   W+   V   G   GHR  + H D     R+LLS   D TIK+W L     M+ +  +R  +  ++
Sbjct:  234 VNAHEDDVNSVCFADLGSNLIYSAGDDGLVKVWDKRAWSDGDVEPVGVFAGHRDGVTHVDSRQDERYLLSNSKDQTIKVWDLRKFSNMSGVEATRACVQSQH 335

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Query:  592 LGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWN--VWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHEN 891
            +  H   +N + F  L  +L++S   D  +++W+   W+   V   G   GHR  + H D     R+LLS   D TIK+W L     M+ +  +R  +  ++
Sbjct:  234 VNAHEDDVNSVCFADLGSNLIYSAGDDGLVKVWDKRAWSDGDVEPVGVFAGHRDGVTHVDSRQDERYLLSNSKDQTIKVWDLRKFSNMSGVEATRACVQSQH 335

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BLAST of EED-1 vs. Ensembl Celegans
Match: wdr-23 (DDB1- and CUL4-associated factor 11 homolog [Source:UniProtKB/Swiss-Prot;Acc:P90794])

HSP 1 Score: 51.6026 bits (122), Expect = 8.615e-7
Identity = 28/102 (27.45%), Postives = 48/102 (47.06%), Query Frame = 1

Query:  592 LGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWN--VWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHEN 891
            +  H   +N + F  L  +L++S   D  +++W+   W+   V   G   GHR  + H D     R+LLS   D TIK+W L     M+ +  +R  +  ++
Sbjct:  266 VNAHEDDVNSVCFADLGSNLIYSAGDDGLVKVWDKRAWSDGDVEPVGVFAGHRDGVTHVDSRQDERYLLSNSKDQTIKVWDLRKFSNMSGVEATRACVQSQH 367

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Query:  592 LGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWN--VWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHEN 891
            +  H   +N + F  L  +L++S   D  +++W+   W+   V   G   GHR  + H D     R+LLS   D TIK+W L     M+ +  +R  +  ++
Sbjct:  266 VNAHEDDVNSVCFADLGSNLIYSAGDDGLVKVWDKRAWSDGDVEPVGVFAGHRDGVTHVDSRQDERYLLSNSKDQTIKVWDLRKFSNMSGVEATRACVQSQH 367

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BLAST of EED-1 vs. Ensembl Fly
Match: escl (gene:FBgn0032391 transcript:FBtr0342581)

HSP 1 Score: 295.049 bits (754), Expect = 5.958e-95
Identity = 155/400 (38.75%), Postives = 221/400 (55.25%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDT---PINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNL--RDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            +K ++ ++E HN+ IFG+  N  +  ++  P +F +VG   V+ YEC   T       I+ L  Y D D +E FY CAWSY                         G  ++A AG +G+IRI +P       N  GHG +INE+ FHP  P LL S SKD+++RLWN+ + V V +FGG EGHR E+L  D D+ G  ++S GMDH++K+W+LD   +  +I  S  +  ++N   F T  +HFPDFS+  IH NY+DC +WFG  VFSKSCE  +V WKPG L+ S        Q+   ++LH F+   C+IW+VRF  +  + +LALGN+LG  +VW L   D  +T+ + +   K              TIRQT F+ D  IL+C CD   + R+DR
Sbjct:   97 YKYSSHVREDHNHQIFGVQFNPFL--DRGQPQVFATVGKDRVSIYECERSTGQESCEGIRLLQVYADPDTDESFYTCAWSY---------------------DSVTGDPVLAAAGYRGVIRIFNPVKHQCSKNYIGHGHAINELKFHPTRPQLLLSGSKDHSLRLWNIQSDVCVAVFGGVEGHRDEVLSVDFDLRGDRIMSSGMDHSLKLWRLDKPDIKEAIELSSGFSPNKNTGPFPTIKEHFPDFSTRDIHRNYVDCVQWFGDFVFSKSCENSIVCWKPGKLSESWHEIKP--QESATTVLHHFDYKMCEIWFVRFAFNAWQKILALGNQLGTTFVWELDCNDPNLTKCSQLVHPKSNS-----------TIRQTSFSKDGSILVCVCDDSTVWRWDR 460

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BLAST of EED-1 vs. Ensembl Fly
Match: escl (gene:FBgn0032391 transcript:FBtr0080286)

HSP 1 Score: 295.049 bits (754), Expect = 5.958e-95
Identity = 155/400 (38.75%), Postives = 221/400 (55.25%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDT---PINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNL--RDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            +K ++ ++E HN+ IFG+  N  +  ++  P +F +VG   V+ YEC   T       I+ L  Y D D +E FY CAWSY                         G  ++A AG +G+IRI +P       N  GHG +INE+ FHP  P LL S SKD+++RLWN+ + V V +FGG EGHR E+L  D D+ G  ++S GMDH++K+W+LD   +  +I  S  +  ++N   F T  +HFPDFS+  IH NY+DC +WFG  VFSKSCE  +V WKPG L+ S        Q+   ++LH F+   C+IW+VRF  +  + +LALGN+LG  +VW L   D  +T+ + +   K              TIRQT F+ D  IL+C CD   + R+DR
Sbjct:   97 YKYSSHVREDHNHQIFGVQFNPFL--DRGQPQVFATVGKDRVSIYECERSTGQESCEGIRLLQVYADPDTDESFYTCAWSY---------------------DSVTGDPVLAAAGYRGVIRIFNPVKHQCSKNYIGHGHAINELKFHPTRPQLLLSGSKDHSLRLWNIQSDVCVAVFGGVEGHRDEVLSVDFDLRGDRIMSSGMDHSLKLWRLDKPDIKEAIELSSGFSPNKNTGPFPTIKEHFPDFSTRDIHRNYVDCVQWFGDFVFSKSCENSIVCWKPGKLSESWHEIKP--QESATTVLHHFDYKMCEIWFVRFAFNAWQKILALGNQLGTTFVWELDCNDPNLTKCSQLVHPKSNS-----------TIRQTSFSKDGSILVCVCDDSTVWRWDR 460

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BLAST of EED-1 vs. Ensembl Fly
Match: esc (gene:FBgn0000588 transcript:FBtr0080325)

HSP 1 Score: 281.952 bits (720), Expect = 2.087e-90
Identity = 151/400 (37.75%), Postives = 219/400 (54.75%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            +K    +KE+H  +IFG++ N  + K+  +P +F + G   VT YEC        ++ LH Y D DP+E FY CAWSY                            ++A AG +G+IR+I    +  + N  GHGQ+INE+ FHP    LL S SKD+ IRLWN+ + V + I GG EGHR E+L  D +M G  ++S GMDH++K+W L+     + I  S  +   ++ + F T  +HFPDFS+  IH NY+DC +WFG  V SKSCE  +V WKPG L+ S        + VKPS     I+ +FE D+C+IW+VRF  +  + ++ALGN+ G +YVW L D    EG  +  L   + +         T+RQ  F+ DA +L+  CD   + R++R
Sbjct:   62 YKYDTHVKENHGANIFGVAFNTLLGKD--EPQVFATAGSNRVTVYECPRQ---GGMQLLHCYADPDPDEVFYTCAWSY---------------------DLKTSSPLLAAAGYRGVIRVIDVEQNEAVGNYIGHGQAINELKFHPHKLQLLLSGSKDHAIRLWNIQSHVCIAILGGVEGHRDEVLSIDFNMRGDRIVSSGMDHSLKLWCLNTPEFHHKIELSNTFSQEKSTLPFPTVTKHFPDFSTRDIHRNYVDCVQWFGNFVLSKSCENAIVCWKPGQLHQSF-------EQVKPSDSSCTIIAEFEYDECEIWFVRFGFNPWQKVIALGNQQGKVYVWEL-DPSDPEGAHMTTLHNSRSV--------ATVRQIAFSRDASVLVYVCDDATVWRWNR 419

[Close]

BLAST of EED-1 vs. Ensembl Fly
Match: Lis-1 (gene:FBgn0015754 transcript:FBtr0087241)

HSP 1 Score: 55.4546 bits (132), Expect = 5.382e-8
Identity = 34/91 (37.36%), Postives = 45/91 (49.45%), Query Frame = 1

Query:  586 FNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGD------VDMAGRFLLSCGMDHTIKIWKLDDS 840
            F+L GH  SI  +IFHP++  L+ S S+D TIR+W+         F   E  RS   H D       D  G+ L SC  D +IK+W    S
Sbjct:  102 FSLTGHRASITRVIFHPIFA-LMVSASEDATIRIWD---------FETGEYERSLKGHTDSVQDVAFDAQGKLLASCSADLSIKLWDFQQS 182

[Close]

BLAST of EED-1 vs. Ensembl Fly
Match: Lis-1 (gene:FBgn0015754 transcript:FBtr0304747)

HSP 1 Score: 55.4546 bits (132), Expect = 5.382e-8
Identity = 34/91 (37.36%), Postives = 45/91 (49.45%), Query Frame = 1

Query:  586 FNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGD------VDMAGRFLLSCGMDHTIKIWKLDDS 840
            F+L GH  SI  +IFHP++  L+ S S+D TIR+W+         F   E  RS   H D       D  G+ L SC  D +IK+W    S
Sbjct:  102 FSLTGHRASITRVIFHPIFA-LMVSASEDATIRIWD---------FETGEYERSLKGHTDSVQDVAFDAQGKLLASCSADLSIKLWDFQQS 182

[Close]

BLAST of EED-1 vs. Ensembl Zebrafish
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:550463])

HSP 1 Score: 292.352 bits (747), Expect = 5.325e-94
Identity = 155/400 (38.75%), Postives = 217/400 (54.25%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKP-----SILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE H   +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW++                      C+    ++A AG +GIIRII+      + +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+LD  RL  +I  S +Y   +    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KP     +IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    +       IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   84 FKCVNSLKEDHGQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYEC---HSQGEIRLLQSYVDADADENFYTCAWTF---------------------DCSSSHPLLAVAGSRGIIRIINHITMQCVKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADFDLLGEKIMSCGMDHSLKLWRLDSERLQRAIRGSYEYNPSKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGRMEDDI-------DRIKPNESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTLPRCTSAIRQTSFSRDSSILIAVCDDASIWRWDR 441

[Close]

BLAST of EED-1 vs. Ensembl Zebrafish
Match: pafah1b1b (platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b [Source:NCBI gene;Acc:394247])

HSP 1 Score: 51.9878 bits (123), Expect = 1.039e-6
Identity = 26/80 (32.50%), Postives = 40/80 (50.00%), Query Frame = 1

Query:  586 FNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIW 825
            + L GH   +  +IFHP++  L+ S S+D TI++W+             +GH   +     D  G+ L SC  D TIK+W
Sbjct:  102 YALSGHRSPVTRVIFHPVF-SLMVSASEDATIKVWDYEAGDFERTL---KGHTDSVQDISFDQTGKLLASCSADMTIKLW 177

[Close]

Query:  586 FNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIW 825
            + L GH   +  +IFHP++  L+ S S+D TI++W+             +GH   +     D  G+ L SC  D TIK+W
Sbjct:  102 YALSGHRSPVTRVIFHPVF-SLMVSASEDATIKVWDYEAGDFERTL---KGHTDSVQDISFDQTGKLLASCSADMTIKLW 177

[Close]

BLAST of EED-1 vs. Ensembl Zebrafish
Match: copa (coatomer protein complex, subunit alpha [Source:ZFIN;Acc:ZDB-GENE-020905-2])

HSP 1 Score: 50.8322 bits (120), Expect = 2.932e-6
Identity = 31/113 (27.43%), Postives = 51/113 (45.13%), Query Frame = 1

Query:  514 QQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMN 852
            Q +    G    I++ +  +   +F L GH   I    FH  YP +L S S D TIR+WN  +   VC+     GH   ++      +   ++S  +D T+++W +   R  N
Sbjct:   63 QPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWIL-SASDDQTIRIWNWQSRTCVCVL---TGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKN 171

[Close]

BLAST of EED-1 vs. Ensembl Zebrafish
Match: pafah1b1a (platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a [Source:NCBI gene;Acc:394246])

HSP 1 Score: 49.6766 bits (117), Expect = 5.571e-6
Identity = 25/80 (31.25%), Postives = 40/80 (50.00%), Query Frame = 1

Query:  586 FNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIW 825
            + L GH   +  +IFHP++  ++ S S+D TI++W+             +GH   +     D  G+ L SC  D TIK+W
Sbjct:  102 YALSGHRSPVTRVIFHPVF-SVIVSASEDATIKVWDHETGDFERTL---KGHTDSVQDISFDHTGKLLASCSADMTIKLW 177

[Close]

BLAST of EED-1 vs. Ensembl Xenopus
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:550079])

HSP 1 Score: 300.056 bits (767), Expect = 6.801e-97
Identity = 155/395 (39.24%), Postives = 219/395 (55.44%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC    P   I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+  +I +S +Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +        +V  +IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    +       IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   79 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYEC---HPQGEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSLRMKTAIRESYEYNPNKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKASESNV--TILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTYPKCASAIRQTSFSRDSSILVAVCDDATIWRWDR 436

[Close]

BLAST of EED-1 vs. Ensembl Xenopus
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:550079])

HSP 1 Score: 295.049 bits (754), Expect = 6.233e-95
Identity = 155/395 (39.24%), Postives = 218/395 (55.19%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC    P   I+ L +Y D+D  E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+  +I +S +Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +        +V  +IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    +       IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   87 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYEC---HPQGEIRLLQSYVDAD--ENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSLRMKTAIRESYEYNPNKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKASESNV--TILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTYPKCASAIRQTSFSRDSSILVAVCDDATIWRWDR 442

[Close]

BLAST of EED-1 vs. Ensembl Xenopus
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:550079])

HSP 1 Score: 295.049 bits (754), Expect = 7.345e-95
Identity = 155/395 (39.24%), Postives = 218/395 (55.19%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC    P   I+ L +Y D+D  E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+  +I +S +Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +        +V  +IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    +       IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   86 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYEC---HPQGEIRLLQSYVDAD--ENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSLRMKTAIRESYEYNPNKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKASESNV--TILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTYPKCASAIRQTSFSRDSSILVAVCDDATIWRWDR 441

[Close]

BLAST of EED-1 vs. Ensembl Xenopus
Match: hnrnpa2b1 (heterogeneous nuclear ribonucleoprotein A2/B1 [Source:Xenbase;Acc:XB-GENE-490993])

HSP 1 Score: 53.9138 bits (128), Expect = 4.190e-7
Identity = 33/136 (24.26%), Postives = 67/136 (49.26%), Query Frame = 1

Query:  511 GQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLH----HENEMVFD 906
             ++++    + G +R+     + ++  L GH  ++  + FHP Y D + S S D  I+LW+V      C+F   +GH   +        G++L S   DH++K+W L   ++M  +++ +  ++    H NE + +
Sbjct:   74 AEELIVAGSQSGSLRVWDLEAAKILRTLMGHKANVCSLDFHP-YGDFVASGSLDTNIKLWDVRRKG--CVFR-YKGHTQAVRCLRFSPDGKWLASASDDHSVKLWDLTAGKMMAELSEHKGPVNIIEFHPNEYLLN 205

[Close]

BLAST of EED-1 vs. Ensembl Xenopus
Match: hnrnpa2b1 (heterogeneous nuclear ribonucleoprotein A2/B1 [Source:Xenbase;Acc:XB-GENE-490993])

HSP 1 Score: 53.9138 bits (128), Expect = 4.398e-7
Identity = 33/135 (24.44%), Postives = 66/135 (48.89%), Query Frame = 1

Query:  511 GQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLH----HENEMVF 903
             ++++    + G +R+     + ++  L GH  ++  + FHP Y D + S S D  I+LW+V      C+F   +GH   +        G++L S   DH++K+W L   ++M  +++ +  ++    H NE + 
Sbjct:   74 AEELIVAGSQSGSLRVWDLEAAKILRTLMGHKANVCSLDFHP-YGDFVASGSLDTNIKLWDVRRKG--CVFR-YKGHTQAVRCLRFSPDGKWLASASDDHSVKLWDLTAGKMMAELSEHKGPVNIIEFHPNEYLL 204

[Close]

BLAST of EED-1 vs. Ensembl Mouse
Match: Eed (embryonic ectoderm development [Source:MGI Symbol;Acc:MGI:95286])

HSP 1 Score: 302.753 bits (774), Expect = 5.044e-98
Identity = 158/400 (39.50%), Postives = 221/400 (55.25%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KPS     IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    + +     IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   82 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDR 439

[Close]

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KPS     IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    + +     IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   82 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDR 439

[Close]

BLAST of EED-1 vs. Ensembl Mouse
Match: Eed (embryonic ectoderm development [Source:MGI Symbol;Acc:MGI:95286])

HSP 1 Score: 302.368 bits (773), Expect = 3.505e-97
Identity = 158/400 (39.50%), Postives = 221/400 (55.25%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KPS     IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    + +     IRQT F+ D+ IL+  CD   I R+DR
Sbjct:  141 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDR 498

[Close]

BLAST of EED-1 vs. Ensembl Mouse
Match: Eed (embryonic ectoderm development [Source:MGI Symbol;Acc:MGI:95286])

HSP 1 Score: 172.555 bits (436), Expect = 1.174e-50
Identity = 84/208 (40.38%), Postives = 117/208 (56.25%), Query Frame = 1

Query:  226 ESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLM 849
            E HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+M
Sbjct:   39 EDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYEC---HSQGEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMM 220

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BLAST of EED-1 vs. Ensembl Mouse
Match: Eed (embryonic ectoderm development [Source:MGI Symbol;Acc:MGI:95286])

HSP 1 Score: 102.064 bits (253), Expect = 1.429e-25
Identity = 45/101 (44.55%), Postives = 65/101 (64.36%), Query Frame = 1

Query:  787 LLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLN---SSLLPTFKIGQ 1080
            ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +      + P   IGQ
Sbjct:    2 IMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPNACIGQ 102

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BLAST of EED-1 vs. UniProt/SwissProt
Match: sp|Q921E6|EED_MOUSE (Polycomb protein EED OS=Mus musculus OX=10090 GN=Eed PE=1 SV=1)

HSP 1 Score: 302.753 bits (774), Expect = 3.528e-97
Identity = 158/400 (39.50%), Postives = 221/400 (55.25%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KPS     IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    + +     IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   82 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDR 439

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BLAST of EED-1 vs. UniProt/SwissProt
Match: sp|O75530|EED_HUMAN (Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2)

HSP 1 Score: 302.753 bits (774), Expect = 3.528e-97
Identity = 158/400 (39.50%), Postives = 221/400 (55.25%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KPS     IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    + +     IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   82 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDR 439

[Close]

BLAST of EED-1 vs. UniProt/SwissProt
Match: sp|Q3SZ25|EED_BOVIN (Polycomb protein EED OS=Bos taurus OX=9913 GN=EED PE=2 SV=1)

HSP 1 Score: 302.753 bits (774), Expect = 3.684e-97
Identity = 158/400 (39.50%), Postives = 221/400 (55.25%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPS-----ILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+MN+I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KPS     IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    + +     IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   82 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDR 439

[Close]

BLAST of EED-1 vs. UniProt/SwissProt
Match: sp|Q6AZS2|EEDB_XENLA (Polycomb protein eed-B OS=Xenopus laevis OX=8355 GN=eed-b PE=1 SV=2)

HSP 1 Score: 300.056 bits (767), Expect = 3.200e-96
Identity = 154/395 (38.99%), Postives = 219/395 (55.44%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC    P  +I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+  +I +S  Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +        +V  +IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    +       IRQT F+ D+ +L+  CD   I R+DR
Sbjct:   79 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYEC---HPQGDIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSLRMKTAIKESYDYNPNKTNRPFVSQKVHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIEKIKASESNV--TILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTYPKCASAIRQTSFSRDSSVLIAVCDDSTIWRWDR 436

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BLAST of EED-1 vs. UniProt/SwissProt
Match: sp|Q28DT7|EED_XENTR (Polycomb protein eed OS=Xenopus tropicalis OX=8364 GN=eed PE=2 SV=1)

HSP 1 Score: 300.056 bits (767), Expect = 3.603e-96
Identity = 155/395 (39.24%), Postives = 219/395 (55.44%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE HN  +FG+  N      + DP++F +VG   VT YEC    P   I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIRII+P     I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+  +I +S +Y  ++    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +        +V  +IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    +       IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   79 FKCVNSLKEDHNQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYEC---HPQGEIRLLQSYVDADADENFYTCAWTY---------------------DSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSLRMKTAIRESYEYNPNKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKASESNV--TILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTYPKCASAIRQTSFSRDSSILVAVCDDATIWRWDR 436

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BLAST of EED-1 vs. TrEMBL
Match: H9CXT3 (EED-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 875.159 bits (2260), Expect = 0.000e+0
Identity = 446/446 (100.00%), Postives = 446/446 (100.00%), Query Frame = 1

Query:   52 MFKEETKLDAKRKLIKAKRKGPLHLEIDKEXXXXXXXXXXXXXXXXXXXXFKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDRT 1389
            MFKEETKLDAKRKLIKAKRKGPLHLEIDKESVSNSSKSLSDSILNSSQLNFKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDRT
Sbjct:    1 MFKEETKLDAKRKLIKAKRKGPLHLEIDKESVSNSSKSLSDSILNSSQLNFKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDRT 446

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BLAST of EED-1 vs. TrEMBL
Match: A0A5B9BXU8 (Embryonic ectoderm development-like protein OS=Dugesia japonica OX=6161 GN=eed PE=2 SV=1)

HSP 1 Score: 784.252 bits (2024), Expect = 0.000e+0
Identity = 387/445 (86.97%), Postives = 414/445 (93.03%), Query Frame = 1

Query:   52 MFKEETKLDAKRKLIKAKRKGPLHLEIDKEXXXXXXXXXXXXXXXXXXXXFKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            M KEE K D KRKLIK KRK   + E+DKES SNSSKS+SD+  N + LNFKQTALIKESHNNSIFGISVN+ IRKNKSDPILFVSVGGQNVTFYECLLDT +NNIKFLHAYKDSDPNEEFYCC WSYYVP+QNR+ +Y D M ESYLE+C  GQQIVACAGKKGIIRIISPNM GVI NL GHGQSINE+IFHPLYPDLLFSFSKDYT+RLWNVWNSVLVCIFGGSEGHRSEILHGDVDM G+FLLSCGMDHTIKIWKLDD+RL N+IAKSRKYLHHENE VFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNS+L PTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLG IY+WNLRD++ITEGNSIFDLKPQ+F++N+KNGLPVTIRQTRFT++AKILLCACDGG+IARFDR
Sbjct:    1 MTKEELKNDTKRKLIKPKRKIISNNELDKESGSNSSKSVSDNNKNLNNLNFKQTALIKESHNNSIFGISVNEHIRKNKSDPILFVSVGGQNVTFYECLLDTTVNNIKFLHAYKDSDPNEEFYCCTWSYYVPYQNRSSSYADSMIESYLENCVAGQQIVACAGKKGIIRIISPNMGGVILNLAGHGQSINEVIFHPLYPDLLFSFSKDYTVRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMTGQFLLSCGMDHTIKIWKLDDTRLTNAIAKSRKYLHHENEFVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSNLTPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGRIYIWNLRDKRITEGNSIFDLKPQEFVVNNKNGLPVTIRQTRFTNEAKILLCACDGGVIARFDR 445

[Close]

BLAST of EED-1 vs. TrEMBL
Match: G4VT41 (Putative embryonic ectoderm development protein OS=Schistosoma mansoni OX=6183 GN=Smp_165220 PE=4 SV=1)

HSP 1 Score: 362.073 bits (928), Expect = 5.763e-117
Identity = 189/434 (43.55%), Postives = 260/434 (59.91%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLL----------DTPINNIKFLHAYKD-SDPNEEFYCCAWSYYVPFQNRNENYRD---------------GMFESYLES-CTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLN--SSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLG--HIYVWNLRDRKITEGNSIFDLKPQKFMINS-----KNGLPVT---IRQTRFTDDAKILLCACDGGLIARFDR 1386
            +K T +I+E+H+ S+FG++ N   R   +DP+LF +V    VT Y+C L           + ++++  L ++ D +   EEFYCCAWS        +  + D               G   S   S     QQ+VA AGK+G+IRI+ P+M+    +L GHG SINE+ FHP  P LLFSFSKDYTIRLWN+ + VLVCIFGG+EGHR+E+LHGD+ + G  LLS GMDH +KIW+L+   L N++  S  Y    N   F   +QHFP+FSS  +HGNY+DC RWFG LV SKSCE  + LWKPG L+  S+ +PT  +  + K SI+HQ +  DC++WY+RFDID+K  +LALG   G   +Y+W+L+  +     +  +L  Q     +       G+P++   IRQTRF DD  ILLC  D GLI RFD+
Sbjct:   78 YKPTCIIRETHSQSVFGVAFNSVNRSQPTDPLLFATVASHYVTVYQCSLKNDLEDKSTQSSDMSSVCLLQSFADPAGDKEEFYCCAWSRDTSGNVASSWWTDCCESRRPRPTLHPHQGPISSSSGSLLPAHQQVVAAAGKRGVIRILCPSMASCPASLVGHGSSINELRFHPRDPALLFSFSKDYTIRLWNIASHVLVCIFGGAEGHRAEVLHGDLSLTGDLLLSAGMDHCVKIWRLNTPELANAVIDSFNYRSRSNPKPFPVLVQHFPEFSSRDVHGNYVDCARWFGSLVISKSCENSVTLWKPGGLDDSSANIPTPGVPTEHKTSIIHQLKATDCNLWYIRFDIDLKNHVLALGTGTGPSRVYLWDLKYPE-----NALNLPAQVLHFPTVSGVGPGGMPLSHSAIRQTRFADDGDILLCVGDNGLIVRFDK 506

[Close]

BLAST of EED-1 vs. TrEMBL
Match: W6UDL5 (Polycomb protein EED OS=Echinococcus granulosus OX=6210 GN=EGR_06227 PE=4 SV=1)

HSP 1 Score: 360.533 bits (924), Expect = 8.031e-117
Identity = 190/440 (43.18%), Postives = 257/440 (58.41%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINN---------IKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKP------------------------------SILHQFELDDCDIWYVRFDIDVKRGLLALGNRLG--HIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPV----TIRQTRFTDDAKILLCACDGGLIARFDR 1386
            F QTA I+ESH   IFG++ N   R + SDP+LF +VG  +VT Y+C    P            I  L ++ D+  +EEFYCCAWS        N + R G+ ++     +  QQI+A AGK+G+IRI+ P++S  + +L GHGQ++NE+ FHP +P LLFSFSKD+T+RLWN+   V+VCIFGG EGHR+E+LHGD+ + G FLL+  MDHTIKIW+LD   + N++  S +Y   +    F T LQHFPDFS+   HGNY+DC RWFG LV SKSCE  +V+W PG + S+  P      D+ P                              S+LHQ  L DCD+WYVRFD+ +++ LLALG  +G   I++W+L D       S   L P+   I +     +     IRQTRFT D +IL+   D GL+ RFDR
Sbjct:   51 FAQTAFIRESHGRPIFGVAFNCDNRSSSSDPLLFATVGANHVTIYQCRELPPPPEGQDATSNPPIHLLQSFSDASSDEEFYCCAWSC-------NLDARRGVAKA-----SSRQQILAVAGKRGVIRILCPSLSKCLDSLIGHGQAVNELKFHPNHPSLLFSFSKDFTVRLWNIATHVMVCIFGGVEGHRAEVLHGDISLTGDFLLTASMDHTIKIWRLDIPEMRNAVRASFEYT--DKRKPFHTLLQHFPDFSTRDAHGNYVDCARWFGSLVISKSCENAVVVWMPGDIESATSPASLDLHDLLPPRLVAIDNSSGRGSGARARQMTGVPLETHCSLLHQLRLPDCDLWYVRFDLHLQQRLLALGTGVGLPRIFLWDLSDL-----GSTLSLVPKVLHITATGAGNLNNFGAIRQTRFTGDGRILVAVGDNGLVVRFDR 471

[Close]

BLAST of EED-1 vs. TrEMBL
Match: A0A068Y217 (Polycomb protein EED OS=Echinococcus multilocularis OX=6211 PE=4 SV=1)

HSP 1 Score: 360.147 bits (923), Expect = 8.912e-117
Identity = 190/440 (43.18%), Postives = 258/440 (58.64%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINN---------IKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKP------------------------------SILHQFELDDCDIWYVRFDIDVKRGLLALGNRLG--HIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPV----TIRQTRFTDDAKILLCACDGGLIARFDR 1386
            F QTA I+ESH   IFG++ N   R + SDP+LF +VG  +VT Y+C    P +          I  L ++ D+  +EEFYCCAWS        N + R G+ ++     +  QQI+A AGK+G+IRI+ P++S  + +L GHGQ++NE+ FHP +P LLFSFSKD+T+RLWN+   V+VCIFGG EGHR+E+LHGD+ + G FLL+  MDHTIKIW+LD   + N++  S +Y   +    F T LQHFPDFS+   HGNY+DC RWFG LV SKSCE  +V+W PG + S+  P      D+ P                              S+LHQ  L DCD+WYVRFD+ +++ LLALG  +G   I++W+L D       S   L P+   I +     +     IRQTRFT D +IL+   D GL+ RFDR
Sbjct:   45 FTQTAFIRESHGRPIFGVAFNCDNRSSSSDPLLFATVGANHVTIYQCRELPPPSEGQDATSNPPIHLLQSFSDAASDEEFYCCAWSC-------NLDARRGVAKA-----SSRQQILAVAGKRGVIRILCPSLSKCLDSLIGHGQAVNELKFHPNHPSLLFSFSKDFTVRLWNIATHVMVCIFGGVEGHRAEVLHGDISLTGDFLLTASMDHTIKIWRLDIPEMRNAVRASFEYT--DKRKPFHTLLQHFPDFSTRDAHGNYVDCARWFGSLVISKSCENAVVVWMPGDIESATSPASLDLHDLLPPRLVAIDNSSGRGSGARTRQMTGVPLETHCSLLHQLRLPDCDLWYVRFDLHLQQRLLALGTGVGLPRIFLWDLSDL-----GSTLSLVPKVLHITATGAGNLNNFGAIRQTRFTGDGRILVAVGDNGLVVRFDR 465

[Close]

BLAST of EED-1 vs. Ensembl Cavefish
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:103041188])

HSP 1 Score: 286.96 bits (733), Expect = 4.432e-92
Identity = 152/400 (38.00%), Postives = 216/400 (54.00%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKP-----SILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE H   +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                       +    ++A AG +GIIRII+      + +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+  +I  S +Y   +    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KP     +IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    +       IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   82 FKCVNSLKEDHGQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYEC---HSHGEIRLLQSYVDADADENFYTCAWTY---------------------DTSTSHPLLAVAGSRGIIRIINHITMQCVKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADFDLLGEKIMSCGMDHSLKLWRINSERMQKAIRCSYEYNPSKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DHIKPNESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTLPKCTSAIRQTSFSRDSSILIAVCDDASIWRWDR 439

[Close]

BLAST of EED-1 vs. Ensembl Cavefish
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:103041188])

HSP 1 Score: 269.24 bits (687), Expect = 1.156e-85
Identity = 136/344 (39.53%), Postives = 194/344 (56.40%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKP-----SILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLR 1218
            FK    +KE H   +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                       +    ++A AG +GIIRII+      + +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  R+  +I  S +Y   +    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KP     +IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L 
Sbjct:   82 FKCVNSLKEDHGQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYEC---HSHGEIRLLQSYVDADADENFYTCAWTY---------------------DTSTSHPLLAVAGSRGIIRIINHITMQCVKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADFDLLGEKIMSCGMDHSLKLWRINSERMQKAIRCSYEYNPSKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DHIKPNESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE 392

[Close]

BLAST of EED-1 vs. Ensembl Cavefish
Match: pafah1b1a (lissencephaly-1 homolog A-like [Source:NCBI gene;Acc:103030333])

HSP 1 Score: 51.9878 bits (123), Expect = 6.883e-7
Identity = 25/80 (31.25%), Postives = 42/80 (52.50%), Query Frame = 1

Query:  586 FNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIW 825
            ++L GH   + ++IFHP++  ++ S S+D TI++W+             +GH   +     D  G+ L SC  D TIK+W
Sbjct:  102 YSLSGHRSPVTKVIFHPVF-SVMVSASEDATIKVWDYETGDFERTL---KGHTDSVQDISFDQTGKLLASCSADMTIKLW 177

[Close]

BLAST of EED-1 vs. Ensembl Cavefish
Match: pafah1b1a (lissencephaly-1 homolog A-like [Source:NCBI gene;Acc:103030333])

HSP 1 Score: 51.9878 bits (123), Expect = 8.409e-7
Identity = 25/80 (31.25%), Postives = 42/80 (52.50%), Query Frame = 1

Query:  586 FNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIW 825
            ++L GH   + ++IFHP++  ++ S S+D TI++W+             +GH   +     D  G+ L SC  D TIK+W
Sbjct:  106 YSLSGHRSPVTKVIFHPVF-SVMVSASEDATIKVWDYETGDFERTL---KGHTDSVQDISFDQTGKLLASCSADMTIKLW 181

[Close]

BLAST of EED-1 vs. Ensembl Cavefish
Match: pafah1b1b (lissencephaly-1 homolog B [Source:NCBI gene;Acc:103047044])

HSP 1 Score: 50.8322 bits (120), Expect = 2.085e-6
Identity = 25/80 (31.25%), Postives = 40/80 (50.00%), Query Frame = 1

Query:  586 FNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIW 825
            + L GH   +  +IFHP++  ++ S S+D TI++W+             +GH   +     D  G+ L SC  D TIK+W
Sbjct:  102 YALSGHRSPVTRVIFHPVF-SVMVSASEDATIKVWDYEAGDFERTL---KGHTDSVQDISFDQTGKLLASCSADMTIKLW 177

[Close]

BLAST of EED-1 vs. Ensembl Sea Lamprey
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:550463])

HSP 1 Score: 209.149 bits (531), Expect = 3.554e-64
Identity = 103/267 (38.58%), Postives = 152/267 (56.93%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSK 1002
            FK    +KE H   +FG+  N      + DP++F +VG   VT YEC        ++ + +Y D + +E FY CAW+Y     +RN ++                 ++  AG +GIIRII+P     + +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    +V +FGG EGHR E+L  D D+ G  ++SCGMDH++K+W+LD  R+  +I  S +Y  ++    F +   H+PDFS+  IH NY+DC RW G L+ SK
Sbjct:   79 FKCVNSLKEDHGQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEVRLMQSYVDVEADENFYTCAWTY-----DRNTSH----------------PLLGIAGSRGIIRIINPITMQCVKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTMVAVFGGVEGHRDEVLSADFDLYGDKIMSCGMDHSLKLWRLDSERMQRAIRGSYEYNPNKTNRPFPSQKVHYPDFSTRDIHRNYVDCVRWLGDLILSK 319

[Close]

BLAST of EED-1 vs. Ensembl Sea Lamprey
Match: ciao1 (cytosolic iron-sulfur assembly component 1 [Source:NCBI gene;Acc:795104])

HSP 1 Score: 53.9138 bits (128), Expect = 3.013e-8
Identity = 32/83 (38.55%), Postives = 46/83 (55.42%), Query Frame = 1

Query:  592 LGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLW----NVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWK 828
            L  H Q +  +++HP   ++L S S D +IRL+    + W+S     F   EGH S +   D D  GR L+SCG D TI+IW+
Sbjct:  145 LNSHTQDVKHVVWHP-NSEVLASASYDNSIRLYREDGDDWSS-----FATLEGHESTVWSIDFDATGRRLVSCGDDKTIRIWQ 221

[Close]

BLAST of EED-1 vs. Ensembl Sea Lamprey
Match: pafah1b1b (platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b [Source:NCBI gene;Acc:394247])

HSP 1 Score: 50.8322 bits (120), Expect = 2.804e-7
Identity = 24/80 (30.00%), Postives = 42/80 (52.50%), Query Frame = 1

Query:  586 FNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIW 825
            + L GH   +  +IFHP++  ++ S S+D TI++W+             +GH   +     D++G+ L SC  D T+K+W
Sbjct:   41 YALSGHRSPVTRVIFHPVF-SVIVSASEDATIKVWDYETGDFERTL---KGHTDSVQDISFDLSGKMLASCSADMTVKLW 116

[Close]

BLAST of EED-1 vs. Ensembl Yeast
Match: CRN1 (Coronin; cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity; plays a role in regulation of actin patch assembly [Source:SGD;Acc:S000004421])

HSP 1 Score: 49.2914 bits (116), Expect = 9.044e-7
Identity = 20/87 (22.99%), Postives = 43/87 (49.43%), Query Frame = 1

Query:  592 LGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMN 852
            L GH + +  +++HP+  ++L S S DYT++LWNV     +        H   +        G +L +   D  +++W + + ++++
Sbjct:  136 LTGHARKVGHVLYHPVAENVLASSSGDYTVKLWNVETGKDMITL----KHPDMVTSMSFSYDGNYLATVARDKKLRVWNIREEKIVS 218

[Close]

BLAST of EED-1 vs. Ensembl Yeast
Match: COP1 (Alpha subunit of COPI vesicle coatomer complex; complex surrounds transport vesicles in the early secretory pathway [Source:SGD;Acc:S000002304])

HSP 1 Score: 48.521 bits (114), Expect = 1.810e-6
Identity = 32/115 (27.83%), Postives = 52/115 (45.22%), Query Frame = 1

Query:  514 QQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWN-SVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNS 855
            Q I   AG    I++ S + +  ++ L GH   +  + FH   P  + S S D TIR+WN  N   + C+     GH   ++          ++S  +D TI+IW +   R  +S
Sbjct:   65 QPIFVSAGDDYTIKVWSLDTNKCLYTLTGHLDYVRTVFFHRELP-WIISASDDQTIRIWNWQNRKEIACL----TGHNHFVMCAQFHPTDDLIVSASLDETIRIWDISGLRKRHS 174

[Close]

BLAST of EED-1 vs. Ensembl Nematostella
Match: EDO42020 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2L1])

HSP 1 Score: 237.654 bits (605), Expect = 3.120e-75
Identity = 123/328 (37.50%), Postives = 183/328 (55.79%), Query Frame = 1

Query:  403 NEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
             E FYCCAW+                      S T G+ ++A AG++ +IR ISP     I +  GHG +IN++ FHPL    L S S+D+++RLWNV    L+ IF G EGHR E+L+ D D+ G  ++SCGMDH++KIW L+  ++  +  +S  Y   +++ VF T   H+PDF++  IH NY+DC RW G LV SKSCE  +V WKP      +     I + +   +   F+   C+IWY+RF +D ++ L+A GN+ G ++VW++          + D    + +    N     +RQT F+ D KIL+C CDGG + R+DR
Sbjct:    1 EESFYCCAWTC---------------------SPTTGELMLAVAGQRAVIRFISPITMSCIKHYIGHGGAINDLKFHPLDQCFLLSGSRDHSLRLWNVKTDALIAIFAGVEGHRDEVLNLDFDILGTRIISCGMDHSLKIWSLETEQIQKACDESYLYDASKSKRVFPTANVHYPDFTTRDIHRNYVDCVRWLGDLVLSKSCENCIVCWKPQDPLDEIFQKVHIDK-IFLVLCILFDFSQCEIWYMRFSLDFEQRLVAAGNQQGKVFVWDI---------GVEDPSKARCITLVHNKCVSAVRQTAFSRDGKILVCVCDGGTVWRWDR 297

[Close]

BLAST of EED-1 vs. Ensembl Nematostella
Match: KATNB1 (Katanin p80 WD40 repeat-containing subunit B1 [Source:UniProtKB/TrEMBL;Acc:A7SV12])

HSP 1 Score: 55.0694 bits (131), Expect = 4.259e-8
Identity = 33/114 (28.95%), Postives = 57/114 (50.00%), Query Frame = 1

Query:  511 GQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMN 852
            G+ +V    + G ++I     + ++  L GH  SI  + FHP + D + S S D  ++LW++      CIF   +GH   + H      GR+++S G D   K+W L   +++N
Sbjct:   72 GEDLVVAGSQSGTLKIWDLEAAKILRTLTGHKSSIRSLDFHP-FGDFVASGSLDTNLKLWDIRRK--GCIF-TYKGHTDCVNHLRFSPDGRWIISGGEDGAAKLWDLTAGKIIN 181

[Close]

BLAST of EED-1 vs. Ensembl Nematostella
Match: EDO42019 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2L0])

HSP 1 Score: 51.6026 bits (122), Expect = 6.969e-8
Identity = 26/66 (39.39%), Postives = 34/66 (51.52%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSD 399
            FK T  +KE H   +F +  N  I+  +SDP  F +VG   VT Y+C        IK L AY+D D
Sbjct:   95 FKCTNFLKEDHKQPLFAVQFNPFIKDEESDPYFFATVGSNRVTIYQC---EEKGVIKLLQAYEDPD 157

[Close]

BLAST of EED-1 vs. Ensembl Nematostella
Match: EDO33837 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR29])

HSP 1 Score: 50.447 bits (119), Expect = 1.114e-6
Identity = 31/107 (28.97%), Postives = 50/107 (46.73%), Query Frame = 1

Query:  586 FNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFD 906
            + L GH  S+N I+F P Y + L + S D T+ LW+    +    F    GH +   H   ++ G  + SC     +K+W   D R ++ +A +    H  N + FD
Sbjct:  433 YTLRGHADSVNSIVFLP-YSNTLLTSSADKTLSLWDARTGLCAQTF---YGHMNSCNHCTFNLKGDTVASCDAYGVVKLW---DVRTVSCMATADLGPHPANRVAFD 532

[Close]

BLAST of EED-1 vs. Ensembl Nematostella
Match: EDO34676 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNL4])

HSP 1 Score: 49.2914 bits (116), Expect = 2.102e-6
Identity = 59/220 (26.82%), Postives = 87/220 (39.55%), Query Frame = 1

Query:  505 TVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLV-CIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWK-LDDSRLM-NSIAKSRKYLHHENEMVFDTFLQHFPDFS--------------SNKIHGNYIDCG----RWFGGLVFSK---------SCEGYLVLWKPGSLNSSLLPTFKI 1074
            T   + +A  GK  +IRI  P+ S  I    GH   I+ + F       LFS S D T+++WN+     V  +F    GH+  +   D     R   + G D T++IWK +++S+L+ N    S   +   NE   D FL    D S               +  HG   D       W   L   K         SC+  + LW+ G    S+ P F +
Sbjct:  202 TTDGKYLASGGKDKLIRIWDPDTSKHIHTFKGHRDVISGLAFR-RGSHQLFSASHDKTVKIWNLDEMAYVETLF----GHQDAVTGIDSLSRDRAATAGGRDRTLRIWKVVEESQLVFNGAGGSIDCIELINE---DHFLSGSDDGSLTMWNTAKKKPLCTVDNAHGKPSDSTTPDESWITALAAVKSTDLVASAGSCDSCVRLWQCGPGYRSIKPLFSV 413

[Close]

BLAST of EED-1 vs. Ensembl Medaka
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:100049503])

HSP 1 Score: 288.886 bits (738), Expect = 8.247e-93
Identity = 153/400 (38.25%), Postives = 215/400 (53.75%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKP-----SILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FK    +KE H   +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIR+I+      I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L  D D+ G  ++SCGMDH++K+W+++  RL  +I  S +Y   +    F +   HFPDFS+  IH NY+DC RW G L+ SKSCE  +V WKPG +   +         +KP     +IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    +       IRQT F+ D+ IL+  CD   I R+DR
Sbjct:   85 FKCVNSLKEDHGQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DTNTSHPLLAVAGSRGIIRVINHITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADFDLLGEKIMSCGMDHSLKLWRINSERLQKAIRGSYEYNPSKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDI-------DHIKPNESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTLPKCTSAIRQTSFSRDSSILIAVCDDASIWRWDR 442

[Close]

BLAST of EED-1 vs. Ensembl Medaka
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:100049503])

HSP 1 Score: 133.65 bits (335), Expect = 9.840e-35
Identity = 72/192 (37.50%), Postives = 98/192 (51.04%), Query Frame = 1

Query:  202 FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMA 777
            FK    +KE H   +FG+  N      + DP++F +VG   VT YEC        I+ L +Y D+D +E FY CAW+Y                            ++A AG +GIIR+I+      I +  GHG +INE+ FHP  P+LL S SKD+ +RLWN+    LV IFGG EGHR E+L    + A
Sbjct:   79 FKCVNSLKEDHGQPLFGVQFN--WHSKEGDPLVFATVGSNRVTLYECHSQ---GEIRLLQSYVDADADENFYTCAWTY---------------------DTNTSHPLLAVAGSRGIIRVINHITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSASCENA 244

HSP 2 Score: 88.5817 bits (218), Expect = 6.426e-19
Identity = 52/147 (35.37%), Postives = 74/147 (50.34%), Query Frame = 1

Query:  979 FGGL------VFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKP-----SILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDR 1386
            FGG+      V S SCE  +V WKPG +   +         +KP     +IL +F+   CDIWY+RF +D  + +LALGN++G +YVW+L          + D    K    +       IRQT F+ D+ IL+  CD   I R+DR
Sbjct:  226 FGGVEGHRDEVLSASCENAIVCWKPGKMEDDI-------DHIKPNESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE---------VEDPHKAKCTTLTLPKCTSAIRQTSFSRDSSILIAVCDDASIWRWDR 356

[Close]

BLAST of EED-1 vs. Ensembl Medaka
Match: katnb1 (katanin regulatory subunit B1 [Source:NCBI gene;Acc:101167102])

HSP 1 Score: 54.299 bits (129), Expect = 1.937e-7
Identity = 36/117 (30.77%), Postives = 57/117 (48.72%), Query Frame = 1

Query:  505 TVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGG-SEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMN 852
            ++ ++ VA   + G IR+     + ++  L GH  SI  + FHP Y   L S S D  I+LW+V     V  F G ++  RS     D    G++L S   D T+K+W L   +++ 
Sbjct:   72 SLSEEQVAAGSQSGSIRVWDLEAAKILQTLMGHKASITSLGFHP-YGQFLASSSMDTNIKLWDVRRKGYVFRFKGHTDAVRSLAFSPD----GKWLASASDDCTVKLWDLSQGKIIT 183

[Close]

Query:  505 TVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGG-SEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMN 852
            ++ ++ VA   + G IR+     + ++  L GH  SI  + FHP Y   L S S D  I+LW+V     V  F G ++  RS     D    G++L S   D T+K+W L   +++ 
Sbjct:   72 SLSEEQVAAGSQSGSIRVWDLEAAKILQTLMGHKASITSLGFHP-YGQFLASSSMDTNIKLWDVRRKGYVFRFKGHTDAVRSLAFSPD----GKWLASASDDCTVKLWDLSQGKIIT 183

[Close]

BLAST of EED-1 vs. Ensembl Medaka
Match: PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1 [Source:NCBI gene;Acc:101169717])

HSP 1 Score: 51.2174 bits (121), Expect = 1.371e-6
Identity = 25/80 (31.25%), Postives = 40/80 (50.00%), Query Frame = 1

Query:  586 FNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIW 825
            + L GH   +  +IFHP++  ++ S S+D TI++W+             +GH   +     D  G+ L SC  D TIK+W
Sbjct:  102 YALSGHRSPVTRVIFHPVF-SVMVSASEDATIKVWDYETGDFERTL---KGHTDSVQDISFDQTGKLLASCSADMTIKLW 177

[Close]

BLAST of EED-1 vs. Planmine SMEST
Match: SMESG000045902.1 (SMESG000045902.1)

HSP 1 Score: 875.159 bits (2260), Expect = 0.000e+0
Identity = 446/446 (100.00%), Postives = 446/446 (100.00%), Query Frame = 1

Query:   52 MFKEETKLDAKRKLIKAKRKGPLHLEIDKEXXXXXXXXXXXXXXXXXXXXFKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDRT 1389
            MFKEETKLDAKRKLIKAKRKGPLHLEIDKESVSNSSKSLSDSILNSSQLNFKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDRT
Sbjct:    1 MFKEETKLDAKRKLIKAKRKGPLHLEIDKESVSNSSKSLSDSILNSSQLNFKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLDTPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLESCTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIHGNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSILHQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIFDLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDRT 446

[Close]

BLAST of EED-1 vs. Planmine SMEST
Match: SMESG000034899.1 (SMESG000034899.1)

HSP 1 Score: 49.2914 bits (116), Expect = 3.870e-6
Identity = 29/89 (32.58%), Postives = 49/89 (55.06%), Query Frame = 1

Query:  592 LGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSI 858
            L GH + I ++ ++    DLLF+ +K+   +  NVW +V     G  +GH+  +   DVD   RFL++   D ++ IW ++   L+NSI
Sbjct:   23 LQGHERPITQVKYN-REGDLLFTIAKE---KEPNVWYTVNGERLGTYDGHKGAVWCLDVDWETRFLITGAADDSLNIWDIETGTLLNSI 107

[Close]

BLAST of EED-1 vs. Planmine SMEST
Match: SMESG000034899.1 (SMESG000034899.1)

HSP 1 Score: 48.9062 bits (115), Expect = 4.177e-6
Identity = 29/89 (32.58%), Postives = 49/89 (55.06%), Query Frame = 1

Query:  592 LGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSI 858
            L GH + I ++ ++    DLLF+ +K+   +  NVW +V     G  +GH+  +   DVD   RFL++   D ++ IW ++   L+NSI
Sbjct:    6 LQGHERPITQVKYN-REGDLLFTIAKE---KEPNVWYTVNGERLGTYDGHKGAVWCLDVDWETRFLITGAADDSLNIWDIETGTLLNSI 90

[Close]

BLAST of EED-1 vs. Planmine SMEST
Match: SMESG000034899.1 (SMESG000034899.1)

HSP 1 Score: 48.9062 bits (115), Expect = 4.299e-6
Identity = 29/89 (32.58%), Postives = 49/89 (55.06%), Query Frame = 1

Query:  592 LGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSRLMNSI 858
            L GH + I ++ ++    DLLF+ +K+   +  NVW +V     G  +GH+  +   DVD   RFL++   D ++ IW ++   L+NSI
Sbjct:   17 LQGHERPITQVKYN-REGDLLFTIAKE---KEPNVWYTVNGERLGTYDGHKGAVWCLDVDWETRFLITGAADDSLNIWDIETGTLLNSI 101

[Close]

BLAST of EED-1 vs. Planmine SMEST
Match: SMESG000077177.1 (SMESG000077177.1)

HSP 1 Score: 49.2914 bits (116), Expect = 5.853e-6
Identity = 29/110 (26.36%), Postives = 47/110 (42.73%), Query Frame = 1

Query:  514 QQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDLLFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCGMDHTIKIWKLDDSR 843
            Q I    G    I++ +      +F L GH   I    FH  YP  + S S D TIR+WN  +   +C+     GH   ++          ++S  +D T+++W +   R
Sbjct:   65 QPIFVSGGDDYKIKVWNYKTKRCLFTLLGHLDYIRTTFFHKEYP-WIISASDDQTIRIWNWQSRTAICVL---TGHSHYVMCAQFHPKEDLVVSASLDQTVRVWDISGLR 170

The following BLAST results are available for this feature:

BLAST of EED-1 vs. Ensembl Human
BLAST of EED-1 vs. Ensembl Celegans
BLAST of EED-1 vs. Ensembl Fly
BLAST of EED-1 vs. Ensembl Zebrafish
BLAST of EED-1 vs. Ensembl Xenopus
BLAST of EED-1 vs. Ensembl Mouse
BLAST of EED-1 vs. UniProt/SwissProt
BLAST of EED-1 vs. TrEMBL
BLAST of EED-1 vs. Ensembl Cavefish
BLAST of EED-1 vs. Ensembl Sea Lamprey
BLAST of EED-1 vs. Ensembl Yeast
BLAST of EED-1 vs. Ensembl Nematostella
BLAST of EED-1 vs. Ensembl Medaka
BLAST of EED-1 vs. Planmine SMEST

BLAST of EED-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
EED	7.347e-98	39.50	embryonic ectoderm development [Source:HGNC Symbol...	[more]
EED	7.347e-98	39.50	embryonic ectoderm development [Source:HGNC Symbol...	[more]
EED	6.171e-97	39.50	embryonic ectoderm development [Source:HGNC Symbol...	[more]
EED	3.244e-92	37.18	embryonic ectoderm development [Source:HGNC Symbol...	[more]
EED	6.531e-91	41.28	embryonic ectoderm development [Source:HGNC Symbol...	[more]

BLAST of EED-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mes-6	1.038e-18	21.63	Polycomb protein mes-6 [Source:UniProtKB/Swiss-Pr...	[more]
wdr-23	7.290e-7	27.45	DDB1- and CUL4-associated factor 11 homolog [Sour...	[more]
wdr-23	7.290e-7	27.45	DDB1- and CUL4-associated factor 11 homolog [Sour...	[more]
wdr-23	8.615e-7	27.45	DDB1- and CUL4-associated factor 11 homolog [Sour...	[more]
wdr-23	8.615e-7	27.45	DDB1- and CUL4-associated factor 11 homolog [Sour...	[more]

BLAST of EED-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
escl	5.958e-95	38.75	gene:FBgn0032391 transcript:FBtr0342581	[more]
escl	5.958e-95	38.75	gene:FBgn0032391 transcript:FBtr0080286	[more]
esc	2.087e-90	37.75	gene:FBgn0000588 transcript:FBtr0080325	[more]
Lis-1	5.382e-8	37.36	gene:FBgn0015754 transcript:FBtr0087241	[more]
Lis-1	5.382e-8	37.36	gene:FBgn0015754 transcript:FBtr0304747	[more]

BLAST of EED-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eed	5.325e-94	38.75	embryonic ectoderm development [Source:NCBI gene;A...	[more]
pafah1b1b	1.039e-6	32.50	platelet-activating factor acetylhydrolase 1b, reg...	[more]
pafah1b1b	1.039e-6	32.50	platelet-activating factor acetylhydrolase 1b, reg...	[more]
copa	2.932e-6	27.43	coatomer protein complex, subunit alpha [Source:ZF...	[more]
pafah1b1a	5.571e-6	31.25	platelet-activating factor acetylhydrolase 1b, reg...	[more]

BLAST of EED-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eed	6.801e-97	39.24	embryonic ectoderm development [Source:NCBI gene;A...	[more]
eed	6.233e-95	39.24	embryonic ectoderm development [Source:NCBI gene;A...	[more]
eed	7.345e-95	39.24	embryonic ectoderm development [Source:NCBI gene;A...	[more]
hnrnpa2b1	4.190e-7	24.26	heterogeneous nuclear ribonucleoprotein A2/B1 [Sou...	[more]
hnrnpa2b1	4.398e-7	24.44	heterogeneous nuclear ribonucleoprotein A2/B1 [Sou...	[more]

BLAST of EED-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Eed	5.044e-98	39.50	embryonic ectoderm development [Source:MGI Symbol;...	[more]
Eed	5.044e-98	39.50	embryonic ectoderm development [Source:MGI Symbol;...	[more]
Eed	3.505e-97	39.50	embryonic ectoderm development [Source:MGI Symbol;...	[more]
Eed	1.174e-50	40.38	embryonic ectoderm development [Source:MGI Symbol;...	[more]
Eed	1.429e-25	44.55	embryonic ectoderm development [Source:MGI Symbol;...	[more]

BLAST of EED-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q921E6\|EED_MOUSE	3.528e-97	39.50	Polycomb protein EED OS=Mus musculus OX=10090 GN=E...	[more]
sp\|O75530\|EED_HUMAN	3.528e-97	39.50	Polycomb protein EED OS=Homo sapiens OX=9606 GN=EE...	[more]
sp\|Q3SZ25\|EED_BOVIN	3.684e-97	39.50	Polycomb protein EED OS=Bos taurus OX=9913 GN=EED ...	[more]
sp\|Q6AZS2\|EEDB_XENLA	3.200e-96	38.99	Polycomb protein eed-B OS=Xenopus laevis OX=8355 G...	[more]
sp\|Q28DT7\|EED_XENTR	3.603e-96	39.24	Polycomb protein eed OS=Xenopus tropicalis OX=8364...	[more]

BLAST of EED-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
H9CXT3	0.000e+0	100.00	EED-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1	[more]
A0A5B9BXU8	0.000e+0	86.97	Embryonic ectoderm development-like protein OS=Dug...	[more]
G4VT41	5.763e-117	43.55	Putative embryonic ectoderm development protein OS...	[more]
W6UDL5	8.031e-117	43.18	Polycomb protein EED OS=Echinococcus granulosus OX...	[more]
A0A068Y217	8.912e-117	43.18	Polycomb protein EED OS=Echinococcus multiloculari...	[more]

BLAST of EED-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eed	4.432e-92	38.00	embryonic ectoderm development [Source:NCBI gene;A...	[more]
eed	1.156e-85	39.53	embryonic ectoderm development [Source:NCBI gene;A...	[more]
pafah1b1a	6.883e-7	31.25	lissencephaly-1 homolog A-like [Source:NCBI gene;A...	[more]
pafah1b1a	8.409e-7	31.25	lissencephaly-1 homolog A-like [Source:NCBI gene;A...	[more]
pafah1b1b	2.085e-6	31.25	lissencephaly-1 homolog B [Source:NCBI gene;Acc:10...	[more]

BLAST of EED-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
eed	3.554e-64	38.58	embryonic ectoderm development [Source:NCBI gene;A...	[more]
ciao1	3.013e-8	38.55	cytosolic iron-sulfur assembly component 1 [Source...	[more]
pafah1b1b	2.804e-7	30.00	platelet-activating factor acetylhydrolase 1b, reg...	[more]

BLAST of EED-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
CRN1	9.044e-7	22.99	Coronin; cortical actin cytoskeletal component tha...	[more]
COP1	1.810e-6	27.83	Alpha subunit of COPI vesicle coatomer complex; co...	[more]

BLAST of EED-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO42020	3.120e-75	37.50	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
KATNB1	4.259e-8	28.95	Katanin p80 WD40 repeat-containing subunit B1 [So...	[more]
EDO42019	6.969e-8	39.39	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33837	1.114e-6	28.97	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34676	2.102e-6	26.82	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of EED-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eed	8.247e-93	38.25	embryonic ectoderm development [Source:NCBI gene;A...	[more]
eed	9.840e-35	37.50	embryonic ectoderm development [Source:NCBI gene;A...	[more]
katnb1	1.937e-7	30.77	katanin regulatory subunit B1 [Source:NCBI gene;Ac...	[more]
katnb1	1.937e-7	30.77	katanin regulatory subunit B1 [Source:NCBI gene;Ac...	[more]
PAFAH1B1	1.371e-6	31.25	platelet activating factor acetylhydrolase 1b regu...	[more]

BLAST of EED-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000045902.1	0.000e+0	100.00	SMESG000045902.1	[more]
SMESG000034899.1	3.870e-6	32.58	SMESG000034899.1	[more]
SMESG000034899.1	4.177e-6	32.58	SMESG000034899.1	[more]
SMESG000034899.1	4.299e-6	32.58	SMESG000034899.1	[more]
SMESG000077177.1	5.853e-6	26.36	SMESG000077177.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30006748
GenBank	AFD29604.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30006748 ID=SMED30006748|Name=EED-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1398bp
TTTTTTTTCATTTACACTAATTTAAATTAACCTTGTTTTTATTTAGATTT
AATGTTTAAAGAAGAAACTAAATTAGACGCAAAACGCAAATTAATTAAGG
CTAAACGTAAAGGACCATTACATTTAGAAATAGATAAGGAAAGTGTTTCT
AATTCCTCTAAAAGTTTATCGGATAGTATATTAAATTCAAGCCAACTAAA
TTTCAAGCAAACTGCTTTAATTAAAGAAAGTCATAATAATTCAATTTTTG
GAATATCTGTCAATGATCGCATCCGTAAAAATAAGTCTGATCCTATTTTA
TTCGTCTCCGTAGGTGGTCAAAATGTTACTTTTTATGAATGTCTCCTTGA
CACACCTATAAATAATATTAAATTTCTTCATGCATATAAAGATTCAGACC
CAAATGAAGAGTTTTATTGTTGTGCATGGTCATATTATGTTCCTTTTCAA
AATCGAAATGAAAATTATAGAGACGGCATGTTTGAATCATACCTGGAAAG
TTGTACTGTAGGTCAGCAAATCGTTGCATGTGCCGGCAAAAAAGGAATTA
TTCGAATTATTAGTCCTAACATGAGTGGTGTTATCTTCAATTTAGGAGGT
CATGGTCAATCAATTAATGAGATTATATTTCATCCTCTTTATCCAGATTT
ATTATTTTCATTTAGCAAAGATTATACTATCAGATTATGGAATGTATGGA
ATAGTGTTTTGGTTTGTATTTTTGGTGGATCAGAAGGTCATAGATCCGAG
ATTCTCCACGGTGATGTTGATATGGCTGGCCGATTTTTACTCTCCTGTGG
AATGGACCACACTATAAAAATATGGAAATTGGATGATTCGCGATTAATGA
ATTCTATTGCAAAATCCCGCAAATATTTGCACCATGAAAATGAGATGGTT
TTCGATACGTTCCTGCAACATTTTCCTGATTTCAGTTCTAATAAAATTCA
TGGAAATTATATCGATTGTGGCCGTTGGTTTGGGGGCCTTGTGTTTTCAA
AGTCTTGCGAAGGGTATCTAGTGCTATGGAAACCGGGCTCGTTGAATTCA
AGCCTTTTGCCGACATTTAAAATCGGCCAAGATGTCAAACCCAGCATTCT
TCATCAGTTTGAACTGGATGATTGCGATATTTGGTATGTCAGATTCGATA
TAGATGTCAAGCGGGGTCTACTGGCCCTTGGCAACCGTTTGGGCCACATA
TATGTCTGGAATTTGAGAGACAGAAAGATCACAGAAGGAAATAGTATTTT
CGATTTGAAGCCGCAAAAGTTCATGATCAATAGCAAAAATGGGCTGCCGG
TCACAATTAGACAAACTCGATTTACCGATGATGCTAAGATATTGCTGTGC
GCGTGTGACGGAGGCCTGATTGCTCGCTTTGATCGTACATAATATTTA

protein sequence of SMED30006748-orf-1

>SMED30006748-orf-1 ID=SMED30006748-orf-1|Name=SMED30006748-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=447bp
MFKEETKLDAKRKLIKAKRKGPLHLEIDKESVSNSSKSLSDSILNSSQLN
FKQTALIKESHNNSIFGISVNDRIRKNKSDPILFVSVGGQNVTFYECLLD
TPINNIKFLHAYKDSDPNEEFYCCAWSYYVPFQNRNENYRDGMFESYLES
CTVGQQIVACAGKKGIIRIISPNMSGVIFNLGGHGQSINEIIFHPLYPDL
LFSFSKDYTIRLWNVWNSVLVCIFGGSEGHRSEILHGDVDMAGRFLLSCG
MDHTIKIWKLDDSRLMNSIAKSRKYLHHENEMVFDTFLQHFPDFSSNKIH
GNYIDCGRWFGGLVFSKSCEGYLVLWKPGSLNSSLLPTFKIGQDVKPSIL
HQFELDDCDIWYVRFDIDVKRGLLALGNRLGHIYVWNLRDRKITEGNSIF
DLKPQKFMINSKNGLPVTIRQTRFTDDAKILLCACDGGLIARFDRT*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000422	tail stripe
PLANA:0002109	X1 cell
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR037352	Polycomb_EED
IPR036322	WD40_repeat_dom_sf
IPR001680	WD40_repeat
IPR015943	WD40/YVTN_repeat-like_dom_sf
IPR017986	WD40_repeat_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0003682	chromatin binding
GO:0042054	histone methyltransferase activity
GO:0042802	identical protein binding

Vocabulary: **biological process**
Term	Definition
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006349	regulation of gene expression by genetic imprinting
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0016569	covalent chromatin modification
GO:0016571	histone methylation
GO:0021510	spinal cord development
GO:0061087	positive regulation of histone H3-K27 methylation
GO:2000011	regulation of adaxial/abaxial pattern formation

Vocabulary: **cellular component**
Term	Definition
GO:0001739	sex chromatin
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005694	chromosome
GO:0005829	cytosol
GO:0035098	ESC/E(Z) complex
GO:0045120	pronucleus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001680	WD40 repeat	SMART	SM00320	WD40_4	coord: 217..259 e-value: 8.9E-4 score: 28.5 coord: 174..214 e-value: 0.0064 score: 25.7 coord: 346..387 e-value: 150.0 score: 3.2
IPR001680	WD40 repeat	PFAM	PF00400	WD40	coord: 229..259 e-value: 0.0054 score: 17.6 coord: 180..214 e-value: 0.21 score: 12.5
IPR001680	WD40 repeat	PROSITE	PS50082	WD_REPEATS_2	coord: 227..268 score: 11.11
IPR001680	WD40 repeat	PROSITE	PS50082	WD_REPEATS_2	coord: 181..215 score: 10.776
IPR015943	WD40/YVTN repeat-like-containing domain superfamily	GENE3D	G3DSA:2.130.10.10		coord: 46..446 e-value: 2.1E-94 score: 318.8
None	No IPR available	PANTHER	PTHR10253	POLYCOMB PROTEIN	coord: 36..445
IPR037352	Polycomb protein EED	PANTHER	PTHR10253:SF5	POLYCOMB PROTEIN EED	coord: 36..445
IPR017986	WD40-repeat-containing domain	PROSITE	PS50294	WD_REPEATS_REGION	coord: 181..268 score: 16.506
IPR036322	WD40-repeat-containing domain superfamily	SUPERFAMILY	SSF50978	WD40 repeat-like	coord: 50..444