Leucine-rich repeat serine/threonine-protein kinase 2-like protein

Overview


Name	Leucine-rich repeat serine/threonine-protein kinase 2-like protein
Smed ID	SMED30006689
Length (bp)	6733

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Leucine-rich repeat serine/threonine-protein kinase 2-like protein (SMED30006689) t-SNE clustered cells

Violin plots show distribution of expression levels for Leucine-rich repeat serine/threonine-protein kinase 2-like protein (SMED30006689) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Leucine-rich repeat serine/threonine-protein kinase 2-like protein (SMED30006689) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30006689

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 20

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30006689	h1SMcG0006393	SmedASXL_004313	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
Smed sexual biotype	SMED30006689	h1SMcG0005166	Contig40297	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30006689	h1SMcG0005166	Contig40297	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30006689	h1SMcG0006897	Contig4364	GPL15192	PMID:29674431 Fincher et al., 2018
nervous system	SMED30006689	h1SMcG0006393	dd_Smed_v4_15919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30006689	h1SMcG0006393	dd_Smed_v4_15919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30006689	h1SMcG0006393	dd_Smed_v4_15919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30006689	h1SMcG0006393	Contig40297	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30006689	h1SMcG0006393	Contig40297	newmark_ests	PMID:29674431 Fincher et al., 2018
nervous system	SMED30006689	h1SMcG0006393	dd_Smed_v4_3239_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30006689	h1SMcG0006393	dd_Smed_v4_3239_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30006689	h1SMcG0006393	dd_Smed_v4_3239_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30006689	h1SMcG0006393	dd_Smed_v4_3239_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30006689	h1SMcG0006393	dd_Smed_v4_3239_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30006689	h1SMcG0006393	dd_Smed_v4_3239_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30006689	h1SMcG0006393	dd_Smed_v4_7343_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30006689	h1SMcG0006393	dd_Smed_v4_7343_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30006689	h1SMcG0006393	dd_Smed_v4_7343_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30006689	h1SMcG0006393	dd_Smed_v4_7343_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30006689	h1SMcG0006393	Contig4364	GPL15192	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Human
Match: LRRK2 (leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618])

HSP 1 Score: 458.759 bits (1179), Expect = 7.677e-130
Identity = 359/1226 (29.28%), Postives = 619/1226 (50.49%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIP-KHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLN-LLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQ-NGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKL------WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDL--HGNRIMNCYVRCL----ECAEQVPLLDIASISLRSDHFFCTSKHQNQFRI----VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA--VDRKRIVLEFAPFKDLKCVFQH-YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVF------ESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFK---VLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNI----FLIDDYIFATSGFVIY---KINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLII--SFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKE---KLNINSK---SYSCRIMCMTIWSGDRYLCAGTGNGYLIIID 6376
            K+  I PEIG L +LT LD+S+N  L+S P+E+G  K   +  L  D L+LN   KHI   A  ++I+++   RLK +V YN ++L+++G  G GKT++L  L++  K      + +  I+V  W +Q +  ++  D  L  WD +G++EF+  H  F++QRA YL V+D++K   E+  +KP L+N+K +A  +PV +VGTHLD   E  RK  C  M     +L +  GFP I    FV+AT  +  +  L+  I+    +  I++  ++ +  P  Y++LE++     K +P   P++  K +  LV +++L L++ EL  AV FL+  GV++HF D    L++LYF++P+W+C I+ + +T+          G IS  D      + F SK+ + F K  +  Q  K+LE + +        +++PS L    P   L    N+  I R++   + P GFW RLI R+  ++      + +   E  L      WR G+ ++     Y ++  +         ++I+V     G  +L Q+VD ID L+EEW+ GL + D+   G  ++  +        E  +++ L D+   +   D     +  Q +  I    + PD++L DLP +I++N  +LE   + + + G G  GSV++  Y+G+  AVK  N  +H+    S RLLRQE+ +L    HPS++SLLA  +  + +V+E A    L  + Q    +L+  L  RIA  V  G+++LH   IIYRD+K  NVL+F+L  ++ I  K+ADYGI++     G    +GTPG++APEV    + Y   AD++SFG+LL++I T G         P EF      GK  D + E+    WP ++  I +C K  P++RP +  +   +     V +     L +   +ECM    + S   +++L  G+  + ++  +D+    ++G +  +EV  +RIL + +       ES I  GTQ+G L   +  + K  +T   + D++ C+   S+    K    L++G A+G +         +D   ++    PL    + N+      + +   +T   V++      +   +  FT  KLIE  +S     +  +  F+++    +++  + Y   +N  ++  +D +  +L   +DC   ++E   K N  SK   SYS R+  + +   +  L  GTG G+++++D
Sbjct: 1256 KLKEIPPEIGCLENLTSLDVSYNLELRSFPNEMG--KLSKIWDLPLDELHLNFDFKHIGCKA--KDIIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGMQSATVGIDVKDWPIQIR-DKRKRDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKARASSSPVILVGTHLDVSDEKQRKA-C--MSKITKELLNKRGFPAIRDYHFVNATEESDALAKLRKTIINESLNFKIRDQLVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVRENQLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQILTVKVEGCPKHPKGIISRRDV-----EKFLSKKRK-FPKNYM-SQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISP-----YMLSGRERALRPNRMYWRQGIYLNWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDICGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGD--LLVNPDQPRLTIPISQIAPDLILADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFN--KHT----SLRLLRQELVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPNEFDELEIQGKLPDPVKEYGCAPWPMVEKLIKQCLKENPQERPTSAQVFDILNSAELVCLTRRILLPKNVIVECMVATHHNSRNASIWLGCGHTDRGQLSFLDL---NTEGYT-SEEVADSRILCLALVHLPVEKESWIVSGTQSGTLLVINTEDGKKRHTLEKMTDSVTCLYCNSFSKQSKQKNFLLVGTADGKLAI------FEDKTVKLKGAAPLKILNIGNVSTPLMCLSESTNSTERNVMWGGCGTKIFSFSNDFTIQKLIETRTSQ----LFSYAAFSDSNIITVVVDTALYIAKQNSPVVEVWDKKTEKLCGLIDCVHFLREVMVKENKESKHKMSYSGRVKTLCL-QKNTALWIGTGGGHILLLD 2438

HSP 2 Score: 66.2402 bits (160), Expect = 1.077e-9
Identity = 54/167 (32.34%), Postives = 88/167 (52.69%), Query Frame = 1

Query: 2380 FKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIK-QFCLSKTDKT-TLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGLNISEKSLHF-LRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL 2871
             +HL  L+L +N++ S P+   + ++ L  LDL  N+ T  P ++ K S + NL++S+N+I     L  T K  TLK F         NLS N+ +    N  DV ++L+ + +   G  IS       L++LK ++L  N I+ ++E FLE C K++S +   N L
Sbjct: 1010 LEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTVKCPTLKQF---------NLSYNQLSFVPENLTDVVEKLEQLILE--GNKISGICSPLRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFL 1165

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Human
Match: LRRK1 (leucine rich repeat kinase 1 [Source:HGNC Symbol;Acc:HGNC:18608])

HSP 1 Score: 329.331 bits (843), Expect = 5.387e-90
Identity = 268/998 (26.85%), Postives = 476/998 (47.70%), Query Frame = 2

Query: 2864 INLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNL-NIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAV--DYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTP------GFPKIS----KIVFVDATNFNQTITNLKNKILTVLND--HTIQNDHLLFEKQPSSYLKLEE--LFQEALKTLPENCPILTEKEVKDLVVKHKL-DLND-EELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAP--TNLSENLNTSKISRIFAFSFLPTGFWPRLIARISV-LAKSFKHLFD-----------------------------ICKLEFKLWRTGVIISMEDSIYLILEG-----KKDTEKNLEIIEISVTKSEL-GIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLEC-------------AEQVPLLDIASISLRS--DHFFCTSKHQN---QFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSV-FKGYYKGKCCAVKYINVVEHSN--DAPSYRLLR---------------QEIDILRRFQHPSIVSLLAVDRKRI--VLEFAPFKDLKCVFQH------YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNI-----GTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQT 5539
            ++ + P +  L SL+ L + +NP L+ LP E+G L   NL  L  + L + N+P  I K    + +L Y   +L+ + +   ++++++G   +GK+++L +LQ +   P+  +  + I  + W++Q     +A     +   WDI G       ++CF + +A Y++V+++    E +  L+  L N++ +AP+A V +VGTHLD ++   R  +   + + +L LC +P      GFP I+      +   +    + +  L   +   + D   TI    L     P SYL L+E  L ++  ++  ++   LT+++++ LV +    D+ D E+L+ A+ FL   G ++HF DT   L NLYFL P W+   + +   +    +  +NG I   D   L     F+++TE        +Q  + L  +++    +N+  ++P  LP +    T+   +   + I R+F  SF+P GFW R IAR+ + LA+    LF+                             + + +   W+ G++++  D  YL +E      KK     ++I    V +SE+     +  I D ++ L+++W+  LT  +  G  +M  YV C  C             +E V   D+    L +    F    +H +     + +VP++ + D P  + +  S LE +  + ++ G GG+G+V ++  Y+G+  AVK  ++ +  N  + P+  +LR               QE  +L   QHP IV+L+ +    +   LE AP   L  V         +I L  +L Q+IAYQ+ SG+ +LH  NII+ D+K  N+LV+SL++   IN+KL+DYGISR+    G +  +GTPGYQAPE+  R I Y    D+FS+G++L+ +       +GHH  +       G +  ++ +     + R+Q  + +C    PE RP A  +   +  P+F    Y     +QT
Sbjct:  560 LDTVPPSVCLLKSLSELYLGNNPGLRELPPELGQLG--NLWQLDTEDLTISNVPAEIQKEGP-KAMLSYLRAQLRKAEKCKLMKMIIVGPPRQGKSTLLEILQ-TGRAPQVVHGEATIRTTKWELQRPAGSRAKVESVEFNVWDIGGPASMATVNQCFFTDKALYVVVWNLALGEEAVANLQFWLLNIEAKAPNAVVLVVGTHLDLIEAKFRVERIATLRAYVLALCRSPSGSRATGFPDITFKHLHEISCKSLEGQEGLRQLIFHVTCSMKDVGSTIGCQRLAGRLIPRSYLSLQEAVLAEQQRRSRDDDVQYLTDRQLEQLVEQTPDNDIKDYEDLQSAISFLIETGTLLHFPDTSHGLRNLYFLDPIWLSECLQRIFNIKGSRSVAKNGVIRAEDLRMLLVGTGFTQQTE--------EQYFQFLAKFEIALPVANDSYLLPHLLPSKPGLDTHGMRHPTANTIQRVFKMSFVPVGFWQRFIARMLISLAEMDLQLFENKKNTKSRNRKVTIYSFTGNQRNRCSTFRVKRNQTIYWQEGLLVTF-DGGYLSVESSDVNWKKKKSGGMKI----VCQSEVRDFSAMAFITDHVNSLIDQWFPALTATESDGTPLMEQYVPCPVCETAWAQHTDPSEKSEDVQYFDMEDCVLTAIERDFISCPRHPDLPVPLQELVPELFMTDFPARLFLENSKLEHSEDEGSVLGQGGSGTVIYRARYQGQPVAVKRFHIKKFKNFANVPADTMLRHLRATDAMKNFSEFRQEASMLHALQHPCIVALIGISIHPLCFALELAPLSSLNTVLSENARDSSFIPLGHMLTQKIAYQIASGLAYLHKKNIIFCDLKSDNILVWSLDVKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPR-IVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIAKKLSKGIR-PVLGQPEEVQFRRLQALMMECWDTKPEKRPLALSVVSQMKDPTFATFMYELCCGKQT 1538

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Human
Match: LRRK1 (leucine rich repeat kinase 1 [Source:HGNC Symbol;Acc:HGNC:18608])

HSP 1 Score: 122.479 bits (306), Expect = 2.067e-27
Identity = 89/329 (27.05%), Postives = 155/329 (47.11%), Query Frame = 2

Query: 4949 VLEFAPFKDLKCVFQH------YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNI-----GTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVFESIIFLGTQNGQLWTYDHLENKFENT---NLVLPDAILCMVMKSYVDYFKVLMM-GLANGTI 5890
             LE AP   L  V         +I L  +L Q+IAYQ+ SG+ +LH  NII+ D+K  N+LV+SL++   IN+KL+DYGISR+    G +  +GTPGYQAPE+  R I Y    D+FS+G++L+ +       +GHH  +       G +  ++ +     + R+Q  + +C    PE RP A  +   +  P+F    Y     +QT         ++     V   +G +  +    ++ + G  + +  C      ++   +  +  ++  T++ +++ Y        NT    L  P  + C +    +     L++ GLA+G +
Sbjct:   10 ALELAPLSSLNTVLSENARDSSFIPLGHMLTQKIAYQIASGLAYLHKKNIIFCDLKSDNILVWSLDVKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPR-IVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIAKKLSKGIR-PVLGQPEEVQFRRLQALMMECWDTKPEKRPLALSVVSQMKDPTFATFMYELCCGKQTAF-----FSSQGQEYTVVFWDGKEESRNYTVVNTEKGLMEVQRMC--CPGMKVSCQLQVQRSLWTATEDQKIYIYTLKGMCPLNTPQQALDTPAVVTCFLAVPVIKKNSYLVLAGLADGLV 329

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Human
Match: STK36 (serine/threonine kinase 36 [Source:HGNC Symbol;Acc:HGNC:17209])

HSP 1 Score: 88.9669 bits (219), Expect = 2.693e-18
Identity = 61/195 (31.28%), Postives = 106/195 (54.36%), Query Frame = 2

Query: 4748 NMFGVGGNGSVFKGY--YKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLL---AVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIP--QGTPGYQAPEVLERCISYKLPADIFSFGILLFNIG 5311
             M G G  G V+KG   Y  +  A+K+I  +  S      R L++EI+I+R  +HP+IV +L     D++ +V+      +L  + +    L    +Q IA Q++S + +LH + I++RD+K QN+L     L+    +KL D+G +R ++    V+   +GTP Y +PE++E    Y   AD++S G +L+ + 
Sbjct:    8 EMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEK--ELRNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNIL-----LAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEER-PYDHTADLWSVGCILYELA 194

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Human
Match: CDK1 (cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722])

HSP 1 Score: 85.5001 bits (210), Expect = 1.477e-17
Identity = 66/212 (31.13%), Postives = 104/212 (49.06%), Query Frame = 2

Query: 4733 NTSKDNMFGVGGNGSVFKGYYK--GKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAV----DRKRIVLEFAPFKDLKCVFQHYIN-------LSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPG-----YQAPEVLERCISYKLPADIFSFGILLFNIGT 5314
            + +K    G G  G V+KG +K  G+  A+K I +       PS  +  +EI +L+  +HP+IVSL  V     R  ++ EF     L    + Y++       + S L++   YQ++ GI F H   +++RD+K QN+L+       K  +KLAD+G++R    FG  I   T       Y++PEVL     Y  P DI+S G +   + T
Sbjct:    3 DYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAI--REISLLKELRHPNIVSLQDVLMQDSRLYLIFEF-----LSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLI-----DDKGTIKLADFGLAR---AFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELAT 199

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Celegans
Match: lrk-1 (Leucine-rich repeat serine/threonine-protein kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TZM3])

HSP 1 Score: 210.305 bits (534), Expect = 6.070e-54
Identity = 265/1122 (23.62%), Postives = 462/1122 (41.18%), Query Frame = 2

Query: 2879 PEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHIS---KNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLL--QGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVD---YKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENN------------RKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQE-ALKTLPENCP-ILTEKEVKDLVVKHKLD------LNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLV---KQCLKVLELYDVVFRNSNNEIIIPSKLPIQ----------------------------------------APTNL----SENL-------NTSKISRIFAFSFLPTGFWPRLIARI---SVLAKSFKHLF-----------DI----CKLEFKLWRTGV-----------------IISMEDSIYLILEGK-KDTEKNLE---------IIEISV------------------TKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLH---GNRIMNCYVRCLECAE------------------------QVPLL------------DIASISLRSDHFF----------------CTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYK---GKCCAVKYINVVEHSNDAP---------------------------SYRLLRQEIDILRRFQHPSIVSLLAVDR--KRIVLEFAPFKDLKCVFQHY----INLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVL--VFSLELSSKINV--KLADYGISRELAPFGFVIP-QGTPGYQAPEVLE--RCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRA----GKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFV 5503
            P++  L+ L++L++S N  +K LP + G+L    L SL   G +L  P       +N +  EI+ Y    L+ S  Y+ LRL++LG  G GK+ + + L  +  + +   ++++  I  + WK ++K S+   +      +  D  GQ E+   H+ FLS+R+  L+++ IT   E + +L   L N+  +AP++ V +VGT+LD++  N+            +K + R+M ++  K     G P+I  ++ +++T+ N  +  L N I     +  +  +  + ++ PSSY+ L ++ +E  ++   E  P ++T +  ++ V K  +        +D E   A  FLH+CG +V F D    L +L F+ P W+   +   + +            S N    L      +  T +FK   L+    Q L +L  +++       +++IPS LP +                                        +PT+     SE++       +   + RI+A +++P+GFW RL+ RI     +  + + +F           DI     K E+ +W+TG+                 +  + D  Y  ++ + KD +K            I+E+ V                  T  E   ++L  I D +D L+E+WY  L    +H   G+ +++ YV C +C                          ++P+             DI+       H F                C S      R + PD V  D+ + + I+P  L+    +  M G G  G VF+   +   G+ C V    ++E  +  P                           +Y   RQE+ +L R +HP+++ L+ V      +V+E AP   L  +   +      LS  +++  A QV   +++LH  +IIYRD+K +NVL   F    S + +V  KL DYGISR + P G      GT G+ APE++       Y    D FSFG+ L+ + T+   P E   H +     G +  L+        P M D +  C    PE RP++  +  F   P F 
Sbjct:  899 PDVARLTLLSMLNLSGNTAIKELPPDYGMLS--RLWSLSLKGCSLKEPLESMVNVENCKTVEIVAYLKTILEESKTYHHLRLMILGSDGVGKSVIWDALCKEAVQKRQPIHSETGVIRQAEWKFEAKRSKGDKNLGPVGFSVIDFGGQREYHSTHQYFLSKRSLNLVLWKITDGDEALAQLDTWLVNIHARAPNSTVILVGTNLDQVASNSSKFGPGYIDIMEQKVRTRYMVADADK----SGLPRIVDVILINSTSRND-VKALLNTIYRTAWEVRMGKERAMEQQIPSSYIALMKVTKELGVEFRKEGQPAVMTVEAYRERVKKRMISKFGRPFRDDIEFYAACTFLHDCGELVRFEDA--TLRDLIFVDPLWLAEFLTSVVILR-----------SPNLPAGLLSTDAINPHTRSFKSGALLMLKTQLLDLLHKFELALATQPRQLLIPSLLPDEYRLRSDFLASAVKIRMKMSQWNVRCPSPAGSPTKSPLRRTSPTDQNGVGSEDVMLQFTYDDDQLLRRIYALAYIPSGFWSRLVTRIVGDKNVCAAIESIFMTTSADRAKIADIATKHAKAEWVVWQTGIELHVKGHSLFTLKQFLPLAEVRDIDYSAIDMRAKDEQKRWRTWNQPSHRPIVEMVVNSLSISAASQHGRKLSMKTDVEGRSRLLAMISDLLDTLLEDWYPALGTRFVHSSEGDLLVSRYVLCPQCVRDAERNGSRSRTSSSASHRRSQDDGELPITSSSHMKGSRTTGDISKCRGGVVHCFVIEECMLAGREYNWVECPSHGGLHMRELAPDTVFADIENALTIHPDQLK----RSRMLGRGAFGFVFRATVRQPNGELCEVAQ-KMLEPVDPGPGGRPSALAAYKAAADKWKRDSMEFACRAYCTSRQELSLLSRMKHPNVIGLVGVCTFPLSLVVELAPLGALNQLLGSHRKAGTKLSLGVIKESAVQVARALEYLHSAHIIYRDLKSENVLGWRFPAPFSPQTDVLLKLGDYGISRSVLPSGGAKGFGGTEGFMAPEIVRFNGEEEYTQKVDCFSFGMFLYELLTL-KFPFESEEHVKERMLDGARPVLLPHELLLPTP-MLDLLVHCWSAHPESRPSSSQLVGFCAAPEFT 1993

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Celegans
Match: gck-3 (Germinal center kinase 3 [Source:UniProtKB/Swiss-Prot;Acc:G5EEN4])

HSP 1 Score: 80.4925 bits (197), Expect = 7.790e-15
Identity = 64/231 (27.71%), Postives = 107/231 (46.32%), Query Frame = 2

Query: 4709 INPSD---LEVNTSK-DNMFGVGGNGSVFKGYY--KGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVS----LLAVDRKRIVLEFAPFKDLKCVFQHYIN-----------LSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQ--------GTPGYQAPEVLERCISYKLPADIFSFGILLFNIGT 5314
            +NP+D    E +  K D   GVG   +VF  Y   + +  A+K IN+ +      S   L  EI  + +  HP++VS     +A +   +V+       +  + +  +            L  V +  +  +V+ G+++ H N  I+RDIK  N+L     L+    +++AD+G+S  LA  G  + +        GTP + APEV+E+   Y   ADI+S GIL   + T
Sbjct:   95 LNPADRWPTEPSAYKLDESIGVGATATVFTAYCLPRNEKVAIKCINLEKCQT---SVDELSHEIQAMSQCNHPNVVSYYTSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNIL-----LADDGTIQIADFGVSGWLASSGGDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELAT 317

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Celegans
Match: gck-2 (Mitogen-activated protein kinase kinase kinase kinase [Source:UniProtKB/TrEMBL;Acc:Q23290])

HSP 1 Score: 80.8777 bits (198), Expect = 8.075e-15
Identity = 75/262 (28.63%), Postives = 124/262 (47.33%), Query Frame = 2

Query: 4757 GVGGNGSVFKGY--YKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIV----SLLAVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISREL-APFG----FVIPQGTPGYQAPEV--LERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAH--------WRAG-KQIDLISEHSSNSW-PRMQDCIHKCTKLVPEDRPNAEDI 5473
            G G  G V+K          AVK + +    N    + +++QEI ++R   HP+I+    S +  DR  IV+E+     L+ ++     LS + +  +  + + G+ +LH    I+RDIK  N+L     LSS  +VKLAD+G++ ++ A  G    F+   GTP + APEV  +E+   Y +  D+++ GI    +G     P  F  H         ++G K   L  +H    W P   D + +C    P+ RP+ E +
Sbjct:   22 GSGTYGEVYKARDIRSDSLAAVKVVKLEAGDN----FAVIQQEIMVIRECSHPNIIAYFGSYIRRDRLWIVMEYCGGGSLQDIYHLTGPLSELQIAFVCRETLRGLNYLHNMGKIHRDIKGANIL-----LSSSGDVKLADFGVAAQITATIGKRKSFI---GTPYWMAPEVACVEKRGGYGMQCDVWATGITAIELGEC--QPPLFDLHPMQVLYLMTKSGYKPPHLKDKH---RWTPLFHDFVRQCLTKNPKKRPSPEKL 266

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Celegans
Match: gck-3 (Germinal center kinase 3 [Source:UniProtKB/Swiss-Prot;Acc:G5EEN4])

HSP 1 Score: 80.1073 bits (196), Expect = 8.563e-15
Identity = 66/237 (27.85%), Postives = 110/237 (46.41%), Query Frame = 2

Query: 4709 INPSD---LEVNTSK-DNMFGVGGNGSVFKGYY--KGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVS----LLAVDRKRIVLEFAPFKDLKCVFQHYIN-----------LSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQ--------GTPGYQAPEVLERCISYKLPADIFSFGILLFNI--GTMGHH 5326
            +NP+D    E +  K D   GVG   +VF  Y   + +  A+K IN+ +      S   L  EI  + +  HP++VS     +A +   +V+       +  + +  +            L  V +  +  +V+ G+++ H N  I+RDIK  N+L     L+    +++AD+G+S  LA  G  + +        GTP + APEV+E+   Y   ADI+S GIL   +  GT  +H
Sbjct:   95 LNPADRWPTEPSAYKLDESIGVGATATVFTAYCLPRNEKVAIKCINLEKCQT---SVDELSHEIQAMSQCNHPNVVSYYTSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNIL-----LADDGTIQIADFGVSGWLASSGGDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYH 323

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Celegans
Match: C25A8.5 (Tyrosine-protein kinase [Source:UniProtKB/TrEMBL;Acc:Q18142])

HSP 1 Score: 76.2554 bits (186), Expect = 1.026e-13
Identity = 71/279 (25.45%), Postives = 123/279 (44.09%), Query Frame = 2

Query: 4703 ILINPSDLEVNTSK-DNMFGVGGNGSVFKGYYKGKC-----CAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKR----IVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTP-GYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHP------AEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHK-CTKLVPEDRPNAEDISKFI 5485
            IL  P ++E +  +     G G  G V+KG    K      CA+K   +   S +    + + +E  ++R   HP++V    V   +    +++E A    L    Q   NL       + YQ   GI ++H   +++RDI  +N L        +  VK+AD+G+SRE   +   + +  P  + APE L+  I Y   +D+F+FGI+ + I   G  P      +E   + R+G ++            R  + + K C    P+DR N  D+ +++
Sbjct:  108 ILKQPWEIEHSQVELTKKLGEGAFGEVWKGKLTLKNGTVENCAIKTAKL--ESLNKEQIKEIMREARLMRNLDHPNVVKFYGVGASQEPLYVIMELADCGALDSYLQKNPNLLPGKKMEMIYQAACGIAYMHEKKLLHRDIAARNCLY------GEGQVKIADFGLSREGNSYVMDLTKKVPIRWLAPETLKAGI-YSPKSDVFAFGIMAWEITENGKEPYPDMRVSEVVGYVRSGHRMRFDPVFVDF---RFGEYVTKHCWAENPDDRVNMSDVLRYL 374

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Fly
Match: Lrrk (gene:FBgn0038816 transcript:FBtr0112788)

HSP 1 Score: 134.42 bits (337), Expect = 9.128e-31
Identity = 100/386 (25.91%), Postives = 180/386 (46.63%), Query Frame = 2

Query: 3281 WDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNIL-KLCSTPGFPKISKIVFVDATNFN-QTITNLKNKILTVLNDHTIQ------NDHLLFEKQPSSYLKLEELFQEALKTLPENC--PILTEKEVKDLVVK------HKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQ--------APTNLSE---------------NLNT-------------------SKISRIFAFSFLPTGFWPRLIARI 4264
            WD  GQ E++  H+ FLS+R+ YL+++ I+   + + +L   L N++ +AP++PV IVGTH D + E+    +   ++  I  K  + P   KI     +D+   + +T+ N+ + +  ++ D  +Q       + +L +K P+SY+ LE++       L      P+L  ++ K LV +      +K   +  EL+ A  + H  GV++H++D    L + YFL PQW+C ++   +T+  +N F   G + L+D   LF+    S + +     + +   + +L  ++V     +  ++IPS LP Q        +   LS+               NLN                      + RI   ++ P+GFW RLI RI
Sbjct: 1021 WDFGGQKEYYATHQYFLSKRSLYLVLWRISDGHKGLAELLQWLGNIQARAPNSPVIIVGTHFDAVGESISPQKAEQLQQLIREKFIAIPDAEKIGLPRVIDSIEISCRTLHNI-HLLANIIYDTAMQLRSPGSKEPMLLQKIPASYIALEDIVNVIACNLRAAGRDPVLDGEQYKRLVTEQMRLHNYKSFRDAAELQQATTWCHENGVLLHYDDA--TLRDYYFLDPQWLCDMLAHVVTVREINPFAPTGVMKLDDLQMLFR----SVQVQGNGNRSYI---VSLLNKFEVALTWDSRTLLIPSLLPSQEAATPNSGSTVKLSQRSRGRSLGCSVSQEVNLNNLIYEQRSAPSSSSSSASVSQGLRRILLMTYFPSGFWSRLITRI 1396

HSP 2 Score: 106.686 bits (265), Expect = 2.712e-22
Identity = 84/271 (31.00%), Postives = 125/271 (46.13%), Query Frame = 2

Query: 4631 CTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFK------GYYKGKCCAVKYINVV--------------------------EHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRK--RIVLEFAPFKDLKCVFQHY----INLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSL-----ELSSK--INVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCI--SYKLPADIFSFGILLF 5302
            C    +     + PD++  D+PD   I PS+  +   K ++ G G  G VFK      G    K  A+K +  V                          +HS  A  Y   RQE+ +L   +HP+IV L+ +  K   +VLE AP   L  + +HY     ++     Q +  Q    I++LH   IIYRD+K +NVLV+ L     E S +  +++K+ADYGISR+ AP G     GT G+ APE++       Y    D FSFG+ ++
Sbjct: 1697 CPVHLEQSMAQLAPDVIFADIPDKHTI-PSECII---KGSLLGRGAFGFVFKANCKVRGARSFKPVAMKMLQPVPPGARAKESALMAFKVAVGKWDRDPLQHSCKA--YCTARQELAVLLTLKHPNIVPLVGICIKPLALVLELAPLGGLDALLRHYRRSGAHMGPHTFQTLVLQAARAIEYLHRRRIIYRDLKSENVLVWELPQPHTEDSPRNLVHIKIADYGISRQTAPSGAKGFGGTEGFMAPEIIRYNGEEEYTEKVDCFSFGMFIY 1961

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Fly
Match: Lrrk (gene:FBgn0038816 transcript:FBtr0334640)

HSP 1 Score: 134.42 bits (337), Expect = 9.981e-31
Identity = 100/386 (25.91%), Postives = 180/386 (46.63%), Query Frame = 2

Query: 3281 WDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNIL-KLCSTPGFPKISKIVFVDATNFN-QTITNLKNKILTVLNDHTIQ------NDHLLFEKQPSSYLKLEELFQEALKTLPENC--PILTEKEVKDLVVK------HKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQ--------APTNLSE---------------NLNT-------------------SKISRIFAFSFLPTGFWPRLIARI 4264
            WD  GQ E++  H+ FLS+R+ YL+++ I+   + + +L   L N++ +AP++PV IVGTH D + E+    +   ++  I  K  + P   KI     +D+   + +T+ N+ + +  ++ D  +Q       + +L +K P+SY+ LE++       L      P+L  ++ K LV +      +K   +  EL+ A  + H  GV++H++D    L + YFL PQW+C ++   +T+  +N F   G + L+D   LF+    S + +     + +   + +L  ++V     +  ++IPS LP Q        +   LS+               NLN                      + RI   ++ P+GFW RLI RI
Sbjct:  998 WDFGGQKEYYATHQYFLSKRSLYLVLWRISDGHKGLAELLQWLGNIQARAPNSPVIIVGTHFDAVGESISPQKAEQLQQLIREKFIAIPDAEKIGLPRVIDSIEISCRTLHNI-HLLANIIYDTAMQLRSPGSKEPMLLQKIPASYIALEDIVNVIACNLRAAGRDPVLDGEQYKRLVTEQMRLHNYKSFRDAAELQQATTWCHENGVLLHYDDA--TLRDYYFLDPQWLCDMLAHVVTVREINPFAPTGVMKLDDLQMLFR----SVQVQGNGNRSYI---VSLLNKFEVALTWDSRTLLIPSLLPSQEAATPNSGSTVKLSQRSRGRSLGCSVSQEVNLNNLIYEQRSAPSSSSSSASVSQGLRRILLMTYFPSGFWSRLITRI 1373

HSP 2 Score: 106.301 bits (264), Expect = 2.968e-22
Identity = 84/271 (31.00%), Postives = 125/271 (46.13%), Query Frame = 2

Query: 4631 CTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFK------GYYKGKCCAVKYINVV--------------------------EHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRK--RIVLEFAPFKDLKCVFQHY----INLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSL-----ELSSK--INVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCI--SYKLPADIFSFGILLF 5302
            C    +     + PD++  D+PD   I PS+  +   K ++ G G  G VFK      G    K  A+K +  V                          +HS  A  Y   RQE+ +L   +HP+IV L+ +  K   +VLE AP   L  + +HY     ++     Q +  Q    I++LH   IIYRD+K +NVLV+ L     E S +  +++K+ADYGISR+ AP G     GT G+ APE++       Y    D FSFG+ ++
Sbjct: 1674 CPVHLEQSMAQLAPDVIFADIPDKHTI-PSECII---KGSLLGRGAFGFVFKANCKVRGARSFKPVAMKMLQPVPPGARAKESALMAFKVAVGKWDRDPLQHSCKA--YCTARQELAVLLTLKHPNIVPLVGICIKPLALVLELAPLGGLDALLRHYRRSGAHMGPHTFQTLVLQAARAIEYLHRRRIIYRDLKSENVLVWELPQPHTEDSPRNLVHIKIADYGISRQTAPSGAKGFGGTEGFMAPEIIRYNGEEEYTEKVDCFSFGMFIY 1938

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Fly
Match: Lrrk (gene:FBgn0038816 transcript:FBtr0334641)

HSP 1 Score: 134.035 bits (336), Expect = 1.391e-30
Identity = 100/386 (25.91%), Postives = 180/386 (46.63%), Query Frame = 2

Query: 3281 WDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNIL-KLCSTPGFPKISKIVFVDATNFN-QTITNLKNKILTVLNDHTIQ------NDHLLFEKQPSSYLKLEELFQEALKTLPENC--PILTEKEVKDLVVK------HKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQ--------APTNLSE---------------NLNT-------------------SKISRIFAFSFLPTGFWPRLIARI 4264
            WD  GQ E++  H+ FLS+R+ YL+++ I+   + + +L   L N++ +AP++PV IVGTH D + E+    +   ++  I  K  + P   KI     +D+   + +T+ N+ + +  ++ D  +Q       + +L +K P+SY+ LE++       L      P+L  ++ K LV +      +K   +  EL+ A  + H  GV++H++D    L + YFL PQW+C ++   +T+  +N F   G + L+D   LF+    S + +     + +   + +L  ++V     +  ++IPS LP Q        +   LS+               NLN                      + RI   ++ P+GFW RLI RI
Sbjct: 1089 WDFGGQKEYYATHQYFLSKRSLYLVLWRISDGHKGLAELLQWLGNIQARAPNSPVIIVGTHFDAVGESISPQKAEQLQQLIREKFIAIPDAEKIGLPRVIDSIEISCRTLHNI-HLLANIIYDTAMQLRSPGSKEPMLLQKIPASYIALEDIVNVIACNLRAAGRDPVLDGEQYKRLVTEQMRLHNYKSFRDAAELQQATTWCHENGVLLHYDDA--TLRDYYFLDPQWLCDMLAHVVTVREINPFAPTGVMKLDDLQMLFR----SVQVQGNGNRSYI---VSLLNKFEVALTWDSRTLLIPSLLPSQEAATPNSGSTVKLSQRSRGRSLGCSVSQEVNLNNLIYEQRSAPSSSSSSASVSQGLRRILLMTYFPSGFWSRLITRI 1464

HSP 2 Score: 106.686 bits (265), Expect = 2.706e-22
Identity = 84/271 (31.00%), Postives = 125/271 (46.13%), Query Frame = 2

Query: 4631 CTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFK------GYYKGKCCAVKYINVV--------------------------EHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRK--RIVLEFAPFKDLKCVFQHY----INLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSL-----ELSSK--INVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCI--SYKLPADIFSFGILLF 5302
            C    +     + PD++  D+PD   I PS+  +   K ++ G G  G VFK      G    K  A+K +  V                          +HS  A  Y   RQE+ +L   +HP+IV L+ +  K   +VLE AP   L  + +HY     ++     Q +  Q    I++LH   IIYRD+K +NVLV+ L     E S +  +++K+ADYGISR+ AP G     GT G+ APE++       Y    D FSFG+ ++
Sbjct: 1765 CPVHLEQSMAQLAPDVIFADIPDKHTI-PSECII---KGSLLGRGAFGFVFKANCKVRGARSFKPVAMKMLQPVPPGARAKESALMAFKVAVGKWDRDPLQHSCKA--YCTARQELAVLLTLKHPNIVPLVGICIKPLALVLELAPLGGLDALLRHYRRSGAHMGPHTFQTLVLQAARAIEYLHRRRIIYRDLKSENVLVWELPQPHTEDSPRNLVHIKIADYGISRQTAPSGAKGFGGTEGFMAPEIIRYNGEEEYTEKVDCFSFGMFIY 2029

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Fly
Match: SAK (gene:FBgn0026371 transcript:FBtr0078387)

HSP 1 Score: 90.1225 bits (222), Expect = 1.502e-17
Identity = 85/297 (28.62%), Postives = 143/297 (48.15%), Query Frame = 2

Query: 4748 NMFGVGGNGSVFKGYYKGKC------CAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA----VDRKRIVLEFAPFKDLKCVFQHYIN-LSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFG--FVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLISEH--SSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVF 5593
            ++ G GG    F   YK +C       A+K I+         + R+ RQE++I  R +HPS++ L       +   +VLE A   +L     H     +      I  QV++G+ +LH +NI++RDI + N+L     LS +++VK+AD+G++ +L       +   GTP Y +PEV+ R  S+ LPAD++S G +L+ +  +G  P E  A      ++ ++SE+   ++     QD I+K  K +P +R   E     +LC  F+             ++C     +    LNVF
Sbjct:   18 HLLGKGG----FATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRV-RQEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLL-----LSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSR-TSHGLPADVWSVGCMLYTL-LVGRPPFETDAVQSTLNKV-VMSEYIMPAHLSYEAQDLINKLLKKLPHERITLE----AVLCHPFM-------------LKCSNGGHSAPGALNVF 284

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Fly
Match: CG7236 (gene:FBgn0031730 transcript:FBtr0302950)

HSP 1 Score: 87.8113 bits (216), Expect = 2.592e-17
Identity = 58/195 (29.74%), Postives = 97/195 (49.74%), Query Frame = 2

Query: 4739 SKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKR----IVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPF-GFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNI 5308
             K +  G G  G V+K   +     V     VE  +D    ++  +EI +L+  +HP++VSLL V R++    +V EF     L  + +H       L ++I YQ + G+ + H    ++RDIK +N+L     L+++  VKL D+G +R L+P   +     T  Y+APE+L     Y  P D+++ G L   +
Sbjct:   48 EKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENIL-----LTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAEL 237

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Zebrafish
Match: lrrk2 (leucine-rich repeat kinase 2 [Source:ZFIN;Acc:ZDB-GENE-071218-6])

HSP 1 Score: 416.387 bits (1069), Expect = 9.696e-117
Identity = 310/1063 (29.16%), Postives = 535/1063 (50.33%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSL-VRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLC----STPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARI-SVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNR-------IMNCYVRCLECAEQVPLLDIASISLRSDHFFCTSKHQN---QFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAV--DRKRIVLEFAPFKDLKCVFQHY-INLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDI-----SKFILCPSFVAIKYVWPLTRQTRI-----ECMTT-----MMNESNILNVFLANGNKFKQE--VRSIDIKSGQSKGKSFCKEVDSNRILSMMVFESI------IFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYF---KVLMMGLANGTI 5890
            ++  I P+IG L  LT LD+SHN  L+S PDE+G  K  +L  L +         KHI   ++ ++I+++   RLK +V Y+ ++L+VLG  G GK+S++   Q  +L+         + +  W V+SK      +  L  W+ SG +E    H  F+S RA YL+++D++K   EIH +KP L+N+K  A   PV +VGTH D  +E       RH++  +LKL     S PGFP I +   + A   ++++  L+  I   L    IQ   ++ +  P  Y++LE+   +     P + P+L    + +++ + +L L + EL  A+ FL   GV++HF+  ++ L +LYF+  QW C II +T+++     +     +     +  F +     ++  F K+ ++ Q  K+LE + +     +++++IPS L    P   L    N+  I R++   + P G+WPR I+R+  V A          K     WR G+ +S     Y ++E     E     I+I+V  S  G  +  Q+VD ID L+EEW+ GL   D+HG          +  +     C +++ L D+ S +  +D      +  +       + PD+VL D P   +++P  LE+  + + M G GG GSV+K  YK +  AVK  N  +H++    +RL+RQE+ +L R  HPS+V LLA   +   +V+E AP+  L  +F+    +LS  L  RIA  V  G+++LH + IIYRD+K  NVL+F+L+  ++I  K+ DYGI++     G    +GTPG++APEV    + Y + AD++SFG+LL+++ T G         P+EF      GK  D + ++  + WP ++  + +C +  P+DRP +  +     S  +LC           L R+  +     EC          N     +V++  G+  ++   V ++D+++    G S  +E+D + IL M++  +       +  G+++G L+  D +  K  +    + D++  +   + + +      L++G A+GT+
Sbjct: 1248 RLTEIPPQIGMLEDLTSLDVSHNEGLRSFPDEMG--KLVHLWDLPLDGLQLQLDLKHI--GSKTKDIIRFLQQRLKKAVPYHRMKLMVLGGSGSGKSSLIQ--QLMRLRRSQWRSDPGVSIRDWPVRSK---DKRNMMLNVWEFSGGEECSGIHPHFMSSRAVYLVLYDLSKGASEIHAIKPWLFNIKAVAGQCPVIVVGTHADLCEE-------RHLQECLLKLQKELQSQPGFPAIRENHVLSACEESESLGRLRKAIYRELIGFKIQGQPVMGQLVPDCYVELEKRLLQERSCAPADFPVLRHSRLMEILQETQLQLEEGELPHAIHFLSEAGVLLHFDPVLQ-LKDLYFIDLQWFCRIISQTLSLKSSGPWDSTKGVVQRSTVEKFVE-----KSRCFPKDHMI-QYFKLLEKFQIALPFDHDQLLIPSSLSDHRPVIELPHCENSEVIIRLYEMPYFPMGYWPRQISRLLEVSAFLLYGREKALKPNRIYWRKGIYLSWSAEAYCLVEALTLEENPASFIKITVPCSRKGRVLFGQVVDHIDSLLEEWFPGLLTTDIHGTGETLLKKWALYSFSDGQNC-QKMLLEDLLS-NTNADGLLVNPEDPSCTLPISQISPDLVLSDQPSSTILDPEQLEMELTAEYMLGDGGFGSVYKAVYKNEEVAVKIFN--KHASALYVHRLVRQELAVLGRLCHPSLVGLLAAGCNPHILVMELAPYGSLDSLFERENGSLSRKLQHRIALHVADGLKYLHSSMIIYRDLKPHNVLLFNLKTDAEIVAKITDYGIAQYCCSMGVRSSEGTPGFRAPEVARGNVIYNVQADVYSFGLLLYDLLTYGERISDGMKFPSEFDEVAVQGKLPDPVKDYGCSPWPEIESLMRECMRENPQDRPTSAQVFDRLNSAEMLC-----------LMRELNVVGFPGECFVVSNSGGAANGGKNPHVWIGGGSSSQKLGCVTAVDLET----GGSLNQELDRSPILCMVIIRAADSCSDWLVAGSESGSLFIMDTINAKVLHRLKSVKDSVTSLYFHTELQHRCLKSYLLVGTADGTL 2268

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Zebrafish
Match: lrrk1 (leucine-rich repeat kinase 1 [Source:ZFIN;Acc:ZDB-GENE-101019-2])

HSP 1 Score: 186.422 bits (472), Expect = 1.272e-46
Identity = 199/809 (24.60%), Postives = 362/809 (44.75%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNL-NIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLS--EKAVD-YKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTP------GFPKIS-KIVFVDATNFNQTITNLKNKILTV-LNDHTIQND---HLLFEKQ-PSSYLKLEELF--QEALKTLPENCPILTEKEVKDLVVKHKL-DLND-EELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLS--ENLNTSKISRIFAFSFLPTGFWPRLIARI------------------------SVLAKSFK--------HLFDICKLEFKLWRTGVIISMEDSIYLILEGKK-DTEKNLEIIEISVTKSEL-GIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECAEQVPLLDI---ASISLRSDHFF---------------CTSKHQNQ---FRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGS-VFKGYYKGKCCAVKYIN---------------VVEH--SNDAP-SYRLLRQEIDILRRFQHPSIVSLLAVDRKRI--VLEFAPFKDLKCVFQ 4993
            ++  + P +  L +L+ L ++ NP ++ LP E+G L   NL  L  + LN+ NIP  + K+     +L Y    L+ +     L+L+V+G   +GK+++L  LQ +       N    +  S W+++  +   + AVD      WDI G       ++CF + +A Y++++++    E +  L+  L N++ +AP++ V +VGTHLD +    R  +   + + IL LC TP      G+P I+ K +   +    + +  LK  +  V  +   I N    H L  +  P SYL L+E    +   +   +    LT+ E++ ++ +    D+ D E+L+ A+ FL   G ++HF+DT   L  LYFL   W+   + + I +    +  +NG I   D   L     F+ +TE        +Q  + L  +++    +++  ++P  LP +   ++      + + I R F  SF+P GFW R IAR+                        S +  SF           F + + +   W+ G++++  D  YL +E    + +K        + +SE      +  I D ++ L+E+W+  LT  +  G+R++  +  C  C+    L D    +S+S    H+F                   H  Q    + +VP++ + D P  + +  SDLE    + ++ G GG+G+ +++  Y+G   A+K  +               +++H  S DA  S+   RQE  +L   QHP IV+L+ +    +   L+ AP   L  V +
Sbjct:  578 QLESVPPSVCALRNLSELYLASNPGIQELPIELGQLS--NLWQLDIEDLNISNIPADVRKDGPA-AVLAYLRAELRGAEPCRLLKLMVVGPPRQGKSALLEGLQ-TGKPSPFINTDCSVHTSSWELERPVGVLKTAVDSVSFNVWDIGGPASMSTVNQCFFTDKALYMVIWNLALGEEAVANLQSWLLNIEARAPNSAVIVVGTHLDLIDTKFRTERVATLRAYILALCRTPSGARCSGYPDITWKHLHEVSCKTLEGLDGLKRLLFQVSCSMKDISNPASCHKLVGRLIPKSYLILQEAIKAERVRRDEADEVQYLTDSELEQIIEQSPASDIKDYEDLQTAISFLMETGSVLHFSDTSHGLCKLYFLDAVWLSECLERIINLRGSRSVARNGVIKAEDLRMLLVGTGFTPQTE--------EQYFQFLAKFEIALPVASSSYLLPHLLPPKPALDIHGFRQQSNNSIQRHFKMSFVPAGFWERFIARMLISLNQMDLQAFETKKNTKNHRNRSTVIYSFAGNQQRNRCSTFRVRRSQTIYWKEGLLVTF-DGGYLSVESSDLNWKKKKSGGIKIICQSETRDFSAMAFITDHVNALIEQWFPALTGSESDGSRLIEQFAPCPFCSSVSRLPDPLPQSSLSQSVVHYFNMEDCVLAAVDKEHITCPNHPKQPVPLQELVPELFMTDFPSRLFLLKSDLEWTEDEADILGQGGSGTIIYRAKYRGHPVAIKRFHFKKCKQQSLNSSTDTMIKHLQSMDASRSFSEFRQESSMLHSLQHPCIVALVGISIHPLCFALQLAPLGSLNTVLE 1373

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Zebrafish
Match: stk36 (serine/threonine kinase 36 (fused homolog, Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030912-6])

HSP 1 Score: 91.2781 bits (225), Expect = 1.199e-17
Identity = 64/195 (32.82%), Postives = 107/195 (54.87%), Query Frame = 2

Query: 4751 MFGVGGNGSVFKGYYK--GKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLL---AVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIP--QGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGT 5314
            + G G  G V+KG  K  G+  A+K+I  V  S      R L++EIDI+R  +HP+IV LL     +R+ +V+      +L  + +   +L    ++ IA Q++S + +LH + I++RD+K QN+L     L     VKL D+G +R ++    V+   +GTP Y +PE++E    Y    D++S G +L+ + T
Sbjct:    9 VIGEGSFGRVYKGRRKFSGQVVALKFIPKVGRSEK--DLRSLKREIDIMRGLKHPNIVLLLDSFETEREVVVVTEYAEGELFQILEDDGSLPEKQVREIACQLVSALYYLHSHRILHRDMKPQNIL-----LGKGGVVKLCDFGFARAMSVSTLVLTSIKGTPLYMSPELVEE-KPYDHSTDLWSLGCILYELHT 195

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Zebrafish
Match: pimr48 (Pim proto-oncogene, serine/threonine kinase, related 48 [Source:ZFIN;Acc:ZDB-GENE-090312-25])

HSP 1 Score: 85.1149 bits (209), Expect = 7.122e-17
Identity = 76/265 (28.68%), Postives = 119/265 (44.91%), Query Frame = 2

Query: 4739 SKDNMFGVGGNGSVFKGYYK--GKCCAVKYINVVEHSNDAPSYRL-------LRQEIDILRRFQH----PSIVSLLA-VDRKR----IVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISK 5479
            +K  + G GG GSVF G  +  G   A+KY+     S D    RL       L  E+ ++ R       PS++ LL   DR R    I+   AP +DL+   +    L   L +++  Q+I+ ++      +++RD+K +N+L+ +       N+KL D+G    L    +    GTP Y  PE L R      PA ++S G+ L+NI      P  FR   R   +  LI     ++    +  I  C    P DRP+ +DI +
Sbjct:   75 AKGPLLGRGGFGSVFAGIRRSDGLPVAIKYV-----SKDRTHTRLKVDGQGRLPLEVALMTRVTSAPACPSVLQLLDWFDRPRRYVLILERLAPCQDLQSFCEENGCLDERLAKKVLVQLIAALKHCESRGVLHRDVKPENLLIST----ESQNIKLLDFGCGDLLKRSAYKYFAGTPAYAPPEWLRRHRYNATPATVWSVGVTLYNI-LCDRFP--FRGAQRVTSKSRLIFTRKLST--ECRHLIRWCLSTAPADRPSLDDIER 325

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Zebrafish
Match: ascl1b (si:ch211-210p4.6 [Source:NCBI gene;Acc:560440])

HSP 1 Score: 78.9518 bits (193), Expect = 1.665e-16
Identity = 104/403 (25.81%), Postives = 184/403 (45.66%), Query Frame = 2

Query: 2879 PEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVE-YNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDIT--KETEEIHKLKPLLW--NLKCQAPHAPVFIVGTHLDKMK-ENNRKTQCRHMESNILKLCSTPGFP--------------------------------KISKIVFVDATNFNQTITNLKNKI-LTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKT--LPENCPILTEKEVKDLVVKHKL-DLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRL 3961
            P +G LS L  L I  N  L  LPD   L +  +LN    +G  L  P        L++I  Y+     ++ + Y    + +        T   +L +G  ++    +++  IE+S + V+    + +   +   WD +GQ+E++  H  F++ +AF +L  +++  K  E   K   + W  NL+ Q P + V +VGTH+D+ + EN  K +  H+E  + K+  T                                    K+ ++V +D T     I  LK +I   VLN  T  +   + +  P SY ++E   QE L+   +PE+   +  ++V    +K++L  L+D++LKL +Q+LH  GVI+ + +  E L    F+KP ++ S + KT+  + L
Sbjct:  142 PLVG-LSRLKELYIERN-QLAELPDR--LFQNSSLNVFKANGNPLRKPPGEVCAGGLKDIQNYFAMLEANAPDVYTVKTMFLGNSMAGKSTLCRSLKEGCPVQVAEADRTVGIEISEFTVR----DGSDSIRFLFWDFAGQEEYYITHHVFITPQAFVILAINLSSYKMDEATFKENVVFWITNLQLQIPDSVVLLVGTHVDQCQDENEVKKKKEHIEEQVKKMLDTHTVNLEQRRKNLQEVDDPSSNSEQINQIERLTEYKLKVLELVPIDCTK-PADIDKLKTRIKAEVLNKDTFPS---IEQTLPRSYYEVENHIQELLENGDIPEHG--VVSQDVLLCELKNRLTTLDDDKLKLILQYLHRIGVIMWYKEIPE-LQESLFVKPSFLIS-LFKTVVRHDL 528

HSP 2 Score: 29.261 bits (64), Expect = 1.665e-16
Identity = 28/112 (25.00%), Postives = 49/112 (43.75%), Query Frame = 1

Query: 2539 LNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGLNISEKSLHFLRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKLD 2874
            + L +N ++Q     TD + L + ++      +NLS N+ TDF +                         +  LRQLK + L  N+I  I E    + +K++ + LS N+L+
Sbjct:   38 VELQRNRLRQI----TDISQLTNLKE------LNLSRNEITDFPV------------------------EIRALRQLKTLYLNQNNIKTIPENVFPSLEKLNFLKLSTNRLE 115

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Xenopus
Match: hes2 (hes family bHLH transcription factor 2 [Source:Xenbase;Acc:XB-GENE-486138])

HSP 1 Score: 477.633 bits (1228), Expect = 8.915e-136
Identity = 354/1215 (29.14%), Postives = 615/1215 (50.62%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIP-KHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTS-VLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLN-TFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKL-WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDL--HGNRIMNCYVRCL----ECAEQVPLLDIASISLRSDHFFCTSKHQNQFRI--VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA--VDRKRIVLEFAPFKDLKCVFQH-YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVF------ESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDY-------IFATSGFVIYKINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYN--FDDQGIQLKPAVDCKELIKEKLNINSK-----SYSCRIMCMTIWSGDRYLCAGTGNGYLIIID 6376
            KI  I PEIG L ++T  DIS+NP+L++ PDE+G  K   +  L  DGL L+I  KHI   A  ++++++   RLK +V YN ++++++G  G GKT+ V  L++  +L+      +  I+V  W +  +   K  +  L  WD +GQ+EF+C+H  F++ +A YL+V+D++K   E+  +KP L+N+K +A  +PV +VGTHLD   E  +K     ++    +LC+  G P I +  FV+A+  +  +  L+  I+    +  I+   +L +  P SYL+LE+      K +P   P+++ + + ++V + +L L++ EL  AV FL+  GV++HF D    L +LYF+ PQW+C II + +T+          G I  ND      + F  K+ + F K  +  Q  K+LE + +      ++++IPS L    P   L    N+  I R++  S+ P GFW RLI R+  ++       +  +   ++ WR G+ ++     Y ++E  K        ++++V     G  +L Q+VD ID L+EEW+ GL +  +   G  ++  +V       +  +++ L D+ + +   D        +    +  + PDIVL DLP +I++N  +LE + + + + G GG GSV++  YKG+  AVK  N  +H+    S RLLRQE+ +L    HPS+V LLA  V  + +V+E AP   L  + Q    +L+  L  RIA  V  G+++LH   IIYRD+K  NVL+F+L  +S I  K+ADYGI++     G    +GTPG++APEV    + Y   AD++SFG+LL++I T G         P EF      G+  D + E++   WP ++  I KC K  P+ RP +  + + +     + +     +      ECM           V++ NG+  K ++  ID+    +KG   C++   +RIL + +       +S I  GTQ+G++   D  + K ++T   L D++ C+  K Y      ++ G ANG +      T+++  ++  +  + + D+    + L +         ++   G  I+ +     +  FT  K I+   +     +     ++E+    + I  Y  +  +   Y   +D +  ++   +DC + +KE      K     +Y+ R+  + +   +  L  GTG G++++ID
Sbjct: 1211 KIKEIPPEIGFLENITSFDISYNPDLRTFPDEMG--KLTKIWDLPLDGLCLDIDLKHIGCKA--KDLIRFLQQRLKKAVPYNRMKVLIVGNTGSGKTTLVQQLMKCRRLEHGAEKATVGIDVKDWPILIRGKIKK-EITLNVWDFAGQEEFYCSHPHFMTPQALYLVVYDLSKGVSEVDAIKPWLFNIKARASSSPVILVGTHLDVSDEKCQKACISKIKQ---ELCNQHGLPSIREYHFVNASEESDLLAKLRKTIIRECLNFKIREQPVLGQLIPDSYLELEKKILNERKNVPLEFPVISHERMLEIVEESQLHLDENELTHAVHFLNESGVLLHFEDPALQLRDLYFVDPQWLCKIIAQILTVRADGCQKYPKGIIHCNDV-----ERFLEKK-KKFPKNYM-SQYFKLLEKFQIALPLGEDQLLIPSSLSDHRPVIELPHCENSEVIIRLYEMSYFPMGFWSRLINRLLEVSTYMLSGRERAQRPNRMYWRQGIYLNWSPEAYCLVESTKLDRNPNSFLKVTVPSCRKGCILLGQVVDHIDSLMEEWFPGLLESGICEEGEALLKKWVLYSFDDGQEHKKILLSDLQAKAEEGDLLVNPEDPRQTIPVSQIAPDIVLADLPRNIMLNAEELEFDQAPEFLLGDGGFGSVYRASYKGEDVAVKIFN--KHT----SSRLLRQELTVLSHLHHPSLVCLLAAGVHPRMLVMELAPKGSLDHLLQQDCASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNSAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILTGGARMVEGLKFPNEFDELAIHGRLPDPVKEYNCAPWPEVEVLIKKCLKENPQQRPTSATVYEILNSAELLCLMRNIVIFSMLTAECMVAASPLVKKHAVWVGNGSTRKGQMCCIDL----NKGGQTCEDFSDSRILCLTLVTLPGEKQSWILAGTQSGEIIAADSEDLKIKHTLHKLTDSVTCLFPKKY-----YILAGTANGRVAV-FENTAVKCTDAAPMKVINIGDSSTPVMHLCESTYSSEKKSVWGICGTKIFSL-----SSEFTVQKTIDTRVAT----LYSHGSYSESNITCIAIDKYIYVAKKISPYVEIWDKKAEKICEVLDCVQFLKEDTVKRRKCKQEEAYTARVKALYL-QKNTALWVGTGGGHILLID 2384

HSP 2 Score: 53.9138 bits (128), Expect = 4.787e-6
Identity = 49/170 (28.82%), Postives = 81/170 (47.65%), Query Frame = 1

Query: 2380 FKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGLNISEKSLHF-LRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKLDFT*N 2886
             + L  L+L+ NS+ S P+S  + +  L  LDL  N     P ++ + S L  L++S+N I              S +    L  +NLS N+   F  N  ++ Q L+ + +   G NISE  +   L +L  I+L  NSI  +   FL++C K+++ + + N L    N
Sbjct:  968 LERLEKLELQHNSLSSFPKSLCEALRSLTYLDLRGNSFKSFPHYILEISSLVFLDVSRNEIG-------PNLDWNSTKMCPNLKQLNLSYNQLMSFPENIGNITQNLEELIME--GNNISEIHIPLCLPELHTINLNKNSIHFLATDFLKDCVKLETFSATTNLLSIAPN 1128

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Xenopus
Match: hes2 (hes family bHLH transcription factor 2 [Source:Xenbase;Acc:XB-GENE-486138])

HSP 1 Score: 476.478 bits (1225), Expect = 1.667e-135
Identity = 354/1215 (29.14%), Postives = 615/1215 (50.62%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIP-KHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTS-VLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLN-TFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKL-WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDL--HGNRIMNCYVRCL----ECAEQVPLLDIASISLRSDHFFCTSKHQNQFRI--VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA--VDRKRIVLEFAPFKDLKCVFQH-YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVF------ESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDY-------IFATSGFVIYKINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYN--FDDQGIQLKPAVDCKELIKEKLNINSK-----SYSCRIMCMTIWSGDRYLCAGTGNGYLIIID 6376
            KI  I PEIG L ++T  DIS+NP+L++ PDE+G  K   +  L  DGL L+I  KHI   A  ++++++   RLK +V YN ++++++G  G GKT+ V  L++  +L+      +  I+V  W +  +   K  +  L  WD +GQ+EF+C+H  F++ +A YL+V+D++K   E+  +KP L+N+K +A  +PV +VGTHLD   E  +K     ++    +LC+  G P I +  FV+A+  +  +  L+  I+    +  I+   +L +  P SYL+LE+      K +P   P+++ + + ++V + +L L++ EL  AV FL+  GV++HF D    L +LYF+ PQW+C II + +T+          G I  ND      + F  K+ + F K  +  Q  K+LE + +      ++++IPS L    P   L    N+  I R++  S+ P GFW RLI R+  ++       +  +   ++ WR G+ ++     Y ++E  K        ++++V     G  +L Q+VD ID L+EEW+ GL +  +   G  ++  +V       +  +++ L D+ + +   D        +    +  + PDIVL DLP +I++N  +LE + + + + G GG GSV++  YKG+  AVK  N  +H+    S RLLRQE+ +L    HPS+V LLA  V  + +V+E AP   L  + Q    +L+  L  RIA  V  G+++LH   IIYRD+K  NVL+F+L  +S I  K+ADYGI++     G    +GTPG++APEV    + Y   AD++SFG+LL++I T G         P EF      G+  D + E++   WP ++  I KC K  P+ RP +  + + +     + +     +      ECM           V++ NG+  K ++  ID+    +KG   C++   +RIL + +       +S I  GTQ+G++   D  + K ++T   L D++ C+  K Y      ++ G ANG +      T+++  ++  +  + + D+    + L +         ++   G  I+ +     +  FT  K I+   +     +     ++E+    + I  Y  +  +   Y   +D +  ++   +DC + +KE      K     +Y+ R+  + +   +  L  GTG G++++ID
Sbjct: 1208 KIKEIPPEIGFLENITSFDISYNPDLRTFPDEMG--KLTKIWDLPLDGLCLDIDLKHIGCKA--KDLIRFLQQRLKKAVPYNRMKVLIVGNTGSGKTTLVQQLMKCRRLEHGAEKATVGIDVKDWPILIRGKIKK-EITLNVWDFAGQEEFYCSHPHFMTPQALYLVVYDLSKGVSEVDAIKPWLFNIKARASSSPVILVGTHLDVSDEKCQKACISKIKQ---ELCNQHGLPSIREYHFVNASEESDLLAKLRKTIIRECLNFKIREQPVLGQLIPDSYLELEKKILNERKNVPLEFPVISHERMLEIVEESQLHLDENELTHAVHFLNESGVLLHFEDPALQLRDLYFVDPQWLCKIIAQILTVRADGCQKYPKGIIHCNDV-----ERFLEKK-KKFPKNYM-SQYFKLLEKFQIALPLGEDQLLIPSSLSDHRPVIELPHCENSEVIIRLYEMSYFPMGFWSRLINRLLEVSTYMLSGRERAQRPNRMYWRQGIYLNWSPEAYCLVESTKLDRNPNSFLKVTVPSCRKGCILLGQVVDHIDSLMEEWFPGLLESGICEEGEALLKKWVLYSFDDGQEHKKILLSDLQAKAEEGDLLVNPEDPRQTIPVSQIAPDIVLADLPRNIMLNAEELEFDQAPEFLLGDGGFGSVYRASYKGEDVAVKIFN--KHT----SSRLLRQELTVLSHLHHPSLVCLLAAGVHPRMLVMELAPKGSLDHLLQQDCASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNSAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILTGGARMVEGLKFPNEFDELAIHGRLPDPVKEYNCAPWPEVEVLIKKCLKENPQQRPTSATVYEILNSAELLCLMRNIVIFSMLTAECMVAASPLVKKHAVWVGNGSTRKGQMCCIDL----NKGGQTCEDFSDSRILCLTLVTLPGEKQSWILAGTQSGEIIAADSEDLKIKHTLHKLTDSVTCLFPKKY-----YILAGTANGRVAV-FENTAVKCTDAAPMKVINIGDSSTPVMHLCESTYSSEKKSVWGICGTKIFSL-----SSEFTVQKTIDTRVAT----LYSHGSYSESNITCIAIDKYIYVAKKISPYVEIWDKKAEKICEVLDCVQFLKEDTVKRRKCKQEEAYTARVKALYL-QKNTALWVGTGGGHILLID 2381

HSP 2 Score: 53.9138 bits (128), Expect = 4.908e-6
Identity = 49/170 (28.82%), Postives = 81/170 (47.65%), Query Frame = 1

Query: 2380 FKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGLNISEKSLHF-LRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKLDFT*N 2886
             + L  L+L+ NS+ S P+S  + +  L  LDL  N     P ++ + S L  L++S+N I              S +    L  +NLS N+   F  N  ++ Q L+ + +   G NISE  +   L +L  I+L  NSI  +   FL++C K+++ + + N L    N
Sbjct:  962 LERLEKLELQHNSLSSFPKSLCEALRSLTYLDLRGNSFKSFPHYILEISSLVFLDVSRNEIG-------PNLDWNSTKMCPNLKQLNLSYNQLMSFPENIGNITQNLEELIME--GNNISEIHIPLCLPELHTINLNKNSIHFLATDFLKDCVKLETFSATTNLLSIAPN 1122

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Xenopus
Match: hes2 (hes family bHLH transcription factor 2 [Source:Xenbase;Acc:XB-GENE-486138])

HSP 1 Score: 473.011 bits (1216), Expect = 1.826e-134
Identity = 354/1220 (29.02%), Postives = 618/1220 (50.66%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIP-KHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTS-VLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLN-TFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKL-WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDL--HGNRIMNCYVRCL----ECAEQVPLLDIASISLRSDHFFCTSKHQNQFRI--VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA--VDRKRIVLEFAPFKDLKCVFQH-YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVF------ESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVM-----KSYVDYFKVLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDY-------IFATSGFVIYKINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYN--FDDQGIQLKPAVDCKELIKEKLNINSK-----SYSCRIMCMTIWSGDRYLCAGTGNGYLIIID 6376
            KI  I PEIG L ++T  DIS+NP+L++ PDE+G  K   +  L  DGL L+I  KHI   A  ++++++   RLK +V YN ++++++G  G GKT+ V  L++  +L+      +  I+V  W +  +   K  +  L  WD +GQ+EF+C+H  F++ +A YL+V+D++K   E+  +KP L+N+K +A  +PV +VGTHLD   E  +K     ++    +LC+  G P I +  FV+A+  +  +  L+  I+    +  I+   +L +  P SYL+LE+      K +P   P+++ + + ++V + +L L++ EL  AV FL+  GV++HF D    L +LYF+ PQW+C II + +T+          G I  ND      + F  K+ + F K  +  Q  K+LE + +      ++++IPS L    P   L    N+  I R++  S+ P GFW RLI R+  ++       +  +   ++ WR G+ ++     Y ++E  K        ++++V     G  +L Q+VD ID L+EEW+ GL +  +   G  ++  +V       +  +++ L D+ + +   D        +    +  + PDIVL DLP +I++N  +LE + + + + G GG GSV++  YKG+  AVK  N  +H+    S RLLRQE+ +L    HPS+V LLA  V  + +V+E AP   L  + Q    +L+  L  RIA  V  G+++LH   IIYRD+K  NVL+F+L  +S I  K+ADYGI++     G    +GTPG++APEV    + Y   AD++SFG+LL++I T G         P EF      G+  D + E++   WP ++  I KC K  P+ RP +  + + +     + +     +      ECM           V++ NG+  K ++  ID+    +KG   C++   +RIL + +       +S I  GTQ+G++   D  + K ++T   L D++ C++      +S   Y+  ++ G ANG +      T+++  ++  +  + + D+    + L +         ++   G  I+ +     +  FT  K I+   +     +     ++E+    + I  Y  +  +   Y   +D +  ++   +DC + +KE      K     +Y+ R+  + +   +  L  GTG G++++ID
Sbjct: 1143 KIKEIPPEIGFLENITSFDISYNPDLRTFPDEMG--KLTKIWDLPLDGLCLDIDLKHIGCKA--KDLIRFLQQRLKKAVPYNRMKVLIVGNTGSGKTTLVQQLMKCRRLEHGAEKATVGIDVKDWPILIRGKIKK-EITLNVWDFAGQEEFYCSHPHFMTPQALYLVVYDLSKGVSEVDAIKPWLFNIKARASSSPVILVGTHLDVSDEKCQKACISKIKQ---ELCNQHGLPSIREYHFVNASEESDLLAKLRKTIIRECLNFKIREQPVLGQLIPDSYLELEKKILNERKNVPLEFPVISHERMLEIVEESQLHLDENELTHAVHFLNESGVLLHFEDPALQLRDLYFVDPQWLCKIIAQILTVRADGCQKYPKGIIHCNDV-----ERFLEKK-KKFPKNYM-SQYFKLLEKFQIALPLGEDQLLIPSSLSDHRPVIELPHCENSEVIIRLYEMSYFPMGFWSRLINRLLEVSTYMLSGRERAQRPNRMYWRQGIYLNWSPEAYCLVESTKLDRNPNSFLKVTVPSCRKGCILLGQVVDHIDSLMEEWFPGLLESGICEEGEALLKKWVLYSFDDGQEHKKILLSDLQAKAEEGDLLVNPEDPRQTIPVSQIAPDIVLADLPRNIMLNAEELEFDQAPEFLLGDGGFGSVYRASYKGEDVAVKIFN--KHT----SSRLLRQELTVLSHLHHPSLVCLLAAGVHPRMLVMELAPKGSLDHLLQQDCASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNSAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILTGGARMVEGLKFPNEFDELAIHGRLPDPVKEYNCAPWPEVEVLIKKCLKENPQQRPTSATVYEILNSAELLCLMRNIVIFSMLTAECMVAASPLVKKHAVWVGNGSTRKGQMCCIDL----NKGGQTCEDFSDSRILCLTLVTLPGEKQSWILAGTQSGEIIAADSEDLKIKHTLHKLTDSVTCLLFSCIQGESPKKYY--ILAGTANGRVAV-FENTAVKCTDAAPMKVINIGDSSTPVMHLCESTYSSEKKSVWGICGTKIFSL-----SSEFTVQKTIDTRVAT----LYSHGSYSESNITCIAIDKYIYVAKKISPYVEIWDKKAEKICEVLDCVQFLKEDTVKRRKCKQEEAYTARVKALYL-QKNTALWVGTGGGHILLID 2324

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Xenopus
Match: hes2 (hes family bHLH transcription factor 2 [Source:Xenbase;Acc:XB-GENE-486138])

HSP 1 Score: 473.396 bits (1217), Expect = 1.857e-134
Identity = 354/1220 (29.02%), Postives = 618/1220 (50.66%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIP-KHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTS-VLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLN-TFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKL-WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDL--HGNRIMNCYVRCL----ECAEQVPLLDIASISLRSDHFFCTSKHQNQFRI--VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA--VDRKRIVLEFAPFKDLKCVFQH-YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVF------ESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVM-----KSYVDYFKVLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDY-------IFATSGFVIYKINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYN--FDDQGIQLKPAVDCKELIKEKLNINSK-----SYSCRIMCMTIWSGDRYLCAGTGNGYLIIID 6376
            KI  I PEIG L ++T  DIS+NP+L++ PDE+G  K   +  L  DGL L+I  KHI   A  ++++++   RLK +V YN ++++++G  G GKT+ V  L++  +L+      +  I+V  W +  +   K  +  L  WD +GQ+EF+C+H  F++ +A YL+V+D++K   E+  +KP L+N+K +A  +PV +VGTHLD   E  +K     ++    +LC+  G P I +  FV+A+  +  +  L+  I+    +  I+   +L +  P SYL+LE+      K +P   P+++ + + ++V + +L L++ EL  AV FL+  GV++HF D    L +LYF+ PQW+C II + +T+          G I  ND      + F  K+ + F K  +  Q  K+LE + +      ++++IPS L    P   L    N+  I R++  S+ P GFW RLI R+  ++       +  +   ++ WR G+ ++     Y ++E  K        ++++V     G  +L Q+VD ID L+EEW+ GL +  +   G  ++  +V       +  +++ L D+ + +   D        +    +  + PDIVL DLP +I++N  +LE + + + + G GG GSV++  YKG+  AVK  N  +H+    S RLLRQE+ +L    HPS+V LLA  V  + +V+E AP   L  + Q    +L+  L  RIA  V  G+++LH   IIYRD+K  NVL+F+L  +S I  K+ADYGI++     G    +GTPG++APEV    + Y   AD++SFG+LL++I T G         P EF      G+  D + E++   WP ++  I KC K  P+ RP +  + + +     + +     +      ECM           V++ NG+  K ++  ID+    +KG   C++   +RIL + +       +S I  GTQ+G++   D  + K ++T   L D++ C++      +S   Y+  ++ G ANG +      T+++  ++  +  + + D+    + L +         ++   G  I+ +     +  FT  K I+   +     +     ++E+    + I  Y  +  +   Y   +D +  ++   +DC + +KE      K     +Y+ R+  + +   +  L  GTG G++++ID
Sbjct: 1248 KIKEIPPEIGFLENITSFDISYNPDLRTFPDEMG--KLTKIWDLPLDGLCLDIDLKHIGCKA--KDLIRFLQQRLKKAVPYNRMKVLIVGNTGSGKTTLVQQLMKCRRLEHGAEKATVGIDVKDWPILIRGKIKK-EITLNVWDFAGQEEFYCSHPHFMTPQALYLVVYDLSKGVSEVDAIKPWLFNIKARASSSPVILVGTHLDVSDEKCQKACISKIKQ---ELCNQHGLPSIREYHFVNASEESDLLAKLRKTIIRECLNFKIREQPVLGQLIPDSYLELEKKILNERKNVPLEFPVISHERMLEIVEESQLHLDENELTHAVHFLNESGVLLHFEDPALQLRDLYFVDPQWLCKIIAQILTVRADGCQKYPKGIIHCNDV-----ERFLEKK-KKFPKNYM-SQYFKLLEKFQIALPLGEDQLLIPSSLSDHRPVIELPHCENSEVIIRLYEMSYFPMGFWSRLINRLLEVSTYMLSGRERAQRPNRMYWRQGIYLNWSPEAYCLVESTKLDRNPNSFLKVTVPSCRKGCILLGQVVDHIDSLMEEWFPGLLESGICEEGEALLKKWVLYSFDDGQEHKKILLSDLQAKAEEGDLLVNPEDPRQTIPVSQIAPDIVLADLPRNIMLNAEELEFDQAPEFLLGDGGFGSVYRASYKGEDVAVKIFN--KHT----SSRLLRQELTVLSHLHHPSLVCLLAAGVHPRMLVMELAPKGSLDHLLQQDCASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNSAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILTGGARMVEGLKFPNEFDELAIHGRLPDPVKEYNCAPWPEVEVLIKKCLKENPQQRPTSATVYEILNSAELLCLMRNIVIFSMLTAECMVAASPLVKKHAVWVGNGSTRKGQMCCIDL----NKGGQTCEDFSDSRILCLTLVTLPGEKQSWILAGTQSGEIIAADSEDLKIKHTLHKLTDSVTCLLFSCIQGESPKKYY--ILAGTANGRVAV-FENTAVKCTDAAPMKVINIGDSSTPVMHLCESTYSSEKKSVWGICGTKIFSL-----SSEFTVQKTIDTRVAT----LYSHGSYSESNITCIAIDKYIYVAKKISPYVEIWDKKAEKICEVLDCVQFLKEDTVKRRKCKQEEAYTARVKALYL-QKNTALWVGTGGGHILLID 2429

HSP 2 Score: 53.9138 bits (128), Expect = 5.130e-6
Identity = 49/170 (28.82%), Postives = 81/170 (47.65%), Query Frame = 1

Query: 2380 FKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGLNISEKSLHF-LRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKLDFT*N 2886
             + L  L+L+ NS+ S P+S  + +  L  LDL  N     P ++ + S L  L++S+N I              S +    L  +NLS N+   F  N  ++ Q L+ + +   G NISE  +   L +L  I+L  NSI  +   FL++C K+++ + + N L    N
Sbjct: 1002 LERLEKLELQHNSLSSFPKSLCEALRSLTYLDLRGNSFKSFPHYILEISSLVFLDVSRNEIG-------PNLDWNSTKMCPNLKQLNLSYNQLMSFPENIGNITQNLEELIME--GNNISEIHIPLCLPELHTINLNKNSIHFLATDFLKDCVKLETFSATTNLLSIAPN 1162

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Xenopus
Match: hes2 (hes family bHLH transcription factor 2 [Source:Xenbase;Acc:XB-GENE-486138])

HSP 1 Score: 473.011 bits (1216), Expect = 2.136e-134
Identity = 354/1220 (29.02%), Postives = 618/1220 (50.66%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIP-KHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTS-VLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLN-TFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKL-WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDL--HGNRIMNCYVRCL----ECAEQVPLLDIASISLRSDHFFCTSKHQNQFRI--VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA--VDRKRIVLEFAPFKDLKCVFQH-YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVF------ESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVM-----KSYVDYFKVLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDY-------IFATSGFVIYKINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYN--FDDQGIQLKPAVDCKELIKEKLNINSK-----SYSCRIMCMTIWSGDRYLCAGTGNGYLIIID 6376
            KI  I PEIG L ++T  DIS+NP+L++ PDE+G  K   +  L  DGL L+I  KHI   A  ++++++   RLK +V YN ++++++G  G GKT+ V  L++  +L+      +  I+V  W +  +   K  +  L  WD +GQ+EF+C+H  F++ +A YL+V+D++K   E+  +KP L+N+K +A  +PV +VGTHLD   E  +K     ++    +LC+  G P I +  FV+A+  +  +  L+  I+    +  I+   +L +  P SYL+LE+      K +P   P+++ + + ++V + +L L++ EL  AV FL+  GV++HF D    L +LYF+ PQW+C II + +T+          G I  ND      + F  K+ + F K  +  Q  K+LE + +      ++++IPS L    P   L    N+  I R++  S+ P GFW RLI R+  ++       +  +   ++ WR G+ ++     Y ++E  K        ++++V     G  +L Q+VD ID L+EEW+ GL +  +   G  ++  +V       +  +++ L D+ + +   D        +    +  + PDIVL DLP +I++N  +LE + + + + G GG GSV++  YKG+  AVK  N  +H+    S RLLRQE+ +L    HPS+V LLA  V  + +V+E AP   L  + Q    +L+  L  RIA  V  G+++LH   IIYRD+K  NVL+F+L  +S I  K+ADYGI++     G    +GTPG++APEV    + Y   AD++SFG+LL++I T G         P EF      G+  D + E++   WP ++  I KC K  P+ RP +  + + +     + +     +      ECM           V++ NG+  K ++  ID+    +KG   C++   +RIL + +       +S I  GTQ+G++   D  + K ++T   L D++ C++      +S   Y+  ++ G ANG +      T+++  ++  +  + + D+    + L +         ++   G  I+ +     +  FT  K I+   +     +     ++E+    + I  Y  +  +   Y   +D +  ++   +DC + +KE      K     +Y+ R+  + +   +  L  GTG G++++ID
Sbjct: 1248 KIKEIPPEIGFLENITSFDISYNPDLRTFPDEMG--KLTKIWDLPLDGLCLDIDLKHIGCKA--KDLIRFLQQRLKKAVPYNRMKVLIVGNTGSGKTTLVQQLMKCRRLEHGAEKATVGIDVKDWPILIRGKIKK-EITLNVWDFAGQEEFYCSHPHFMTPQALYLVVYDLSKGVSEVDAIKPWLFNIKARASSSPVILVGTHLDVSDEKCQKACISKIKQ---ELCNQHGLPSIREYHFVNASEESDLLAKLRKTIIRECLNFKIREQPVLGQLIPDSYLELEKKILNERKNVPLEFPVISHERMLEIVEESQLHLDENELTHAVHFLNESGVLLHFEDPALQLRDLYFVDPQWLCKIIAQILTVRADGCQKYPKGIIHCNDV-----ERFLEKK-KKFPKNYM-SQYFKLLEKFQIALPLGEDQLLIPSSLSDHRPVIELPHCENSEVIIRLYEMSYFPMGFWSRLINRLLEVSTYMLSGRERAQRPNRMYWRQGIYLNWSPEAYCLVESTKLDRNPNSFLKVTVPSCRKGCILLGQVVDHIDSLMEEWFPGLLESGICEEGEALLKKWVLYSFDDGQEHKKILLSDLQAKAEEGDLLVNPEDPRQTIPVSQIAPDIVLADLPRNIMLNAEELEFDQAPEFLLGDGGFGSVYRASYKGEDVAVKIFN--KHT----SSRLLRQELTVLSHLHHPSLVCLLAAGVHPRMLVMELAPKGSLDHLLQQDCASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNSAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILTGGARMVEGLKFPNEFDELAIHGRLPDPVKEYNCAPWPEVEVLIKKCLKENPQQRPTSATVYEILNSAELLCLMRNIVIFSMLTAECMVAASPLVKKHAVWVGNGSTRKGQMCCIDL----NKGGQTCEDFSDSRILCLTLVTLPGEKQSWILAGTQSGEIIAADSEDLKIKHTLHKLTDSVTCLLFSCIQGESPKKYY--ILAGTANGRVAV-FENTAVKCTDAAPMKVINIGDSSTPVMHLCESTYSSEKKSVWGICGTKIFSL-----SSEFTVQKTIDTRVAT----LYSHGSYSESNITCIAIDKYIYVAKKISPYVEIWDKKAEKICEVLDCVQFLKEDTVKRRKCKQEEAYTARVKALYL-QKNTALWVGTGGGHILLID 2429

HSP 2 Score: 53.9138 bits (128), Expect = 4.479e-6
Identity = 49/170 (28.82%), Postives = 81/170 (47.65%), Query Frame = 1

Query: 2380 FKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGLNISEKSLHF-LRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKLDFT*N 2886
             + L  L+L+ NS+ S P+S  + +  L  LDL  N     P ++ + S L  L++S+N I              S +    L  +NLS N+   F  N  ++ Q L+ + +   G NISE  +   L +L  I+L  NSI  +   FL++C K+++ + + N L    N
Sbjct: 1002 LERLEKLELQHNSLSSFPKSLCEALRSLTYLDLRGNSFKSFPHYILEISSLVFLDVSRNEIG-------PNLDWNSTKMCPNLKQLNLSYNQLMSFPENIGNITQNLEELIME--GNNISEIHIPLCLPELHTINLNKNSIHFLATDFLKDCVKLETFSATTNLLSIAPN 1162

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Mouse
Match: Lrrk2 (leucine-rich repeat kinase 2 [Source:MGI Symbol;Acc:MGI:1913975])

HSP 1 Score: 462.996 bits (1190), Expect = 2.900e-131
Identity = 357/1224 (29.17%), Postives = 618/1224 (50.49%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIP-KHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLN-LLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQN--GSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKL------WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCL------ECAEQVPLLDIASISLRSDHFFCTSKHQNQFRI--VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA--VDRKRIVLEFAPFKDLKCVFQH-YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVF------ESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFK---VLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDYIFATSGFVIYK------INLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLII--SFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKE---KLNINSK---SYSCRIMCMTIWSGDRYLCAGTGNGYLIIID 6376
            K+  I PEIG L +LT LD+S+N  L+S P+E+G  K   +  L  DGL+LN   KH+   A  ++I+++   RLK +V YN ++L+++G  G GKT++L  L++  K +      +  I+V  W +Q +  ++  D  L  WD +G++EF+  H  F++QRA YL V+D++K   E+  +KP L+N+K +A  +PV +VGTHLD   E  RK     +   +L   +  GFP I    FV+AT  +  +  L+  I+    +  I++  ++ +  P  Y++LE++     K +P   P++  K +  LV +H+L L++ EL  AV FL+  GV++HF D    L++LYF++P+W+C ++ + +T+ +++  +++  G IS  D      + F SK+ + F K  ++ Q  K+LE + +        +++PS L    P   L    N+  I R++   + P GFW RLI R+  ++      F +   E  L      WR G+ ++     Y ++  +    +    ++I+V     G  +L ++VD ID L+EEW+ GL + D+ G          L      E  +++ L ++   +   D      + +    I  + PD++L DLP +I++N  +LE   + + + G G  GSV++  Y+G+  AVK  N  +H+    S RLLRQE+ +L    HPS++SLLA  +  + +V+E A    L  + Q    +L+  L  RIA  V  G+++LH   IIYRD+K  NVL+F+L  ++ I  K+ADYGI++     G    +GTPG++APEV    + Y   AD++SFG+LL +I T G         P EF      GK  D + E+    WP ++  I KC K  P++RP +  +   +     + +     + +   +ECM      S    ++L  GN  K ++   D+ + +       +EV  +RIL + +       ES +  GTQ+G L   +  E    +T   + D++ C+   S     K    L++G A+G +       +++   +  L  L + D   T +  + + + ++   + +        + S D   FT  KLIE  ++     +  +  F+++    L +  + Y   +N  ++  +D +  +L   +DC   +KE   KLN  SK   SYS R+  + +   +  L  GTG G+++++D
Sbjct: 1256 KLKEIPPEIGCLENLTSLDVSYNLELRSFPNEMG--KLSKIWDLPLDGLHLNFDFKHVGCKA--KDIIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKMKKPELGMQGATVGIDVRDWSIQIR-GKRRKDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKARASSSPVILVGTHLDVSDEKQRKACISKITKELL---NKRGFPTIRDYHFVNATEESDALAKLRKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKAVPTEFPVINRKHLLQLVNEHQLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKVMAQILTV-KVDGCLKHPKGIISRRDV-----EKFLSKK-KRFPKNYMM-QYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISP-----FMLSGRERALRPNRMYWRQGIYLNWSPEAYCLVGSEVLDNRPESFLKITVPSCRKGCILLGRVVDHIDSLMEEWFPGLLEIDICGEGETLLKKWALYSFNDGEEHQKILLDELMKKAEEGDLLINPDQPRLTIPISQIAPDLILADLPRNIMLNNDELEFEEAPEFLLGDGSFGSVYRAAYEGEEVAVKIFN--KHT----SLRLLRQELVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLHDIWTTGSRIMEGLRFPNEFDELAIQGKLPDPVKEYGCAPWPMVEKLITKCLKENPQERPTSAQVFDILNSAELICLMRHILIPKNIIVECMVATNLNSKSATLWLGCGNTEKGQLSLFDLNTERYS----YEEVADSRILCLALVHLAAEKESWVVCGTQSGALLVINVEEETKRHTLEKMTDSVTCLHCNSLAKQSKQSNFLLVGTADGNLMI-FEDKAVKCKGAAPLKTLHIGDVS-TPLMCLSESLNSSERHITWGGCGTKVFSFSND---FTIQKLIETKTNQ----LFSYAAFSDSNIIALAVDTALYIAKKNSPVVEVWDKKTEKLCELIDCVHFLKEVMVKLNKESKHQLSYSGRVKALCL-QKNTALWIGTGGGHILLLD 2438

HSP 2 Score: 65.4698 bits (158), Expect = 1.224e-9
Identity = 53/168 (31.55%), Postives = 83/168 (49.40%), Query Frame = 1

Query: 2374 SLFKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKI--NEIGLNISEKSLHFLRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL 2871
            S  +HLT L+L +NS+ S P+   + ++ L  LDL  N+ T  P FV K   + NL+ S+N+I            L    K   L  +NLS N+ +    N   V ++L+ + +  N+I    S  S   L++LK ++L  N I  +   FLE C K++S +   N L
Sbjct: 1008 SHLEHLTKLELHQNSLTSFPQQLCETLKCLIHLDLHSNKFTSFPSFVLKMPRITNLDASRNDIG-------PTVVLDPAMKCPSLKQLNLSYNQLSSIPENLAQVVEKLEQLLLEGNKISGICSPLS---LKELKILNLSKNHIPSLPGDFLEACSKVESFSARMNFL 1165

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Mouse
Match: Lrrk1 (leucine-rich repeat kinase 1 [Source:MGI Symbol;Acc:MGI:2142227])

HSP 1 Score: 327.02 bits (837), Expect = 2.054e-89
Identity = 267/994 (26.86%), Postives = 476/994 (47.89%), Query Frame = 2

Query: 2864 INLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNL-NIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAV--DYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTP------GFPKIS--KIVFVDATNF--NQTITNLKNKILTVLND--HTIQNDHLLFEKQPSSYLKLEE--LFQEALKTLPENCPILTEKEVKDLVVKHKL-DLND-EELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAP--TNLSENLNTSKISRIFAFSFLPTGFWPRLIARISV-LAKSFKHLFD-----------------------------ICKLEFKLWRTGVIISMEDSIYLILEGKK-DTEKNLEIIEISVTKSEL-GIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLEC-------------AEQVPLLDIASISLRS--DHFFCTSKHQN---QFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSV-FKGYYKGKCCAVK--YINVVEHSNDAPSYRLLR---------------QEIDILRRFQHPSIVSLLAVDRKRI--VLEFAPFKDLKCVFQH------YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNI-----GTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQT 5539
            ++ + P +  L +L+ L + +NP L+ LP E+G L   NL  L  + LN+ N+P  + K    +  L +   +L+ + +   ++++++G   +GK+++L +LQ +   P+  +  + I  + W++Q     KA     +   WDI G       ++CF + +A Y++V+++    E +  L+  L N++ +AP+A V +VGTHLD ++   R  +   + + +L LC +P      GFP I+   +  +   N    + +  L   +   + D   TI    L     P SY+ L+E  L ++  ++L +    LT++++  LV +    D+ D E+L+ A+ FL   G ++HF DT   L NLYFL P W+   + +   +    +  +NG I   D   L     F+++TE        +Q  + L  +++    +N+  ++P  LP +    T+   +   + I R+F  SF+P GFW R IAR+ + LA+    LF+                             + + +   W+ G++++  D  YL +E    + +K        + +SE+     +  I D ++ L+++W+  LT  +  G  +M  YV C  C             +E V   D+    L +    F    +H +     + +VP++ + D P  + +  S LE    ++++ G GG+G+V ++  Y+G+  AVK  +I   ++S +AP+  +LR               QE  +L   QHP IVSL+ +    +   LE AP   L  V         ++ L  +L Q+IAYQ+ SG+ +LH  NII+ D+K  N+LV+SL     IN+KL+DYGISR+    G +  +GTPGYQAPE+  R I Y    D+FS+G++L+ +       +GHH  +       G +  ++ +     + R+Q  + +C    PE RP A  +   +  P+F    Y+ P  +Q+
Sbjct:  560 LDAVPPSVCLLKNLSELYLGNNPGLRELPPELGQLG--NLWQLDIEDLNISNVPAEVRKEGP-KATLSFLRAQLRKAEKCKLMKMILVGPPRQGKSTLLEILQ-TGKAPQLAHSEATIRTTKWELQRPAGSKAKVESVEFNVWDIGGPASMATVNQCFFTDKALYVVVWNLALGEEAVANLQFWLLNIEAKAPNAVVLVVGTHLDLIEAKFRVERIATLRAYVLALCRSPSGSRATGFPDITFKHLHEISCKNLEGQEGLRQLIFHVTCNMKDVGSTIGCQKLAGRLIPRSYISLQEAVLAEQQRRSLGDQVQYLTDRQLDQLVEQTPGNDIKDYEDLQSAISFLIETGTLLHFPDTSHGLRNLYFLDPIWLSECLQRIFNIKGSRSVAKNGVIQAEDLRMLLVGTGFTQQTE--------EQYFQFLAKFEIALPVANDSYLLPHLLPSKPGLDTHSMRHPMANTIQRVFKMSFVPVGFWQRFIARMLISLAEMDLQLFENKKNTKSRNRKVTIYSFTGSQRNRCSTFRVRRNQTIYWQEGLLVTF-DGGYLSVESSDVNWKKKKSGGIKIICQSEMRDFSAMAFITDHVNSLIDQWFPALTATESDGTPLMEQYVPCPVCEASWAQHADPNERSESVQYFDMEDCVLTAIERDFISCPRHPDLPVPLQELVPELFMTDFPARLFLENSKLEHTEGENSILGQGGSGTVIYQARYQGQPVAVKRFHIKKFKNSANAPADTMLRHLRAMDAMKNFSDFRQEASMLHALQHPCIVSLIGISIHPLCFALELAPLGSLNTVLSENAKDSSFMPLGHMLTQKIAYQIASGLAYLHKKNIIFCDLKSDNILVWSLSAKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPR-IVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIVKKLSKGIR-PVLGQPEEVQFHRLQALMMECWDTKPEKRPLALSVVSQMKDPTFATFMYMLPCGKQS 1538

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Mouse
Match: Lrrk1 (leucine-rich repeat kinase 1 [Source:MGI Symbol;Acc:MGI:2142227])

HSP 1 Score: 184.111 bits (466), Expect = 9.433e-49
Identity = 132/456 (28.95%), Postives = 223/456 (48.90%), Query Frame = 2

Query: 4325 WRTGVIISMEDSIYLILEGKK-DTEKNLEIIEISVTKSEL-GIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLEC-------------AEQVPLLDIASISLRS--DHFFCTSKHQN---QFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSV-FKGYYKGKCCAVK--YINVVEHSNDAPSYRLLR---------------QEIDILRRFQHPSIVSLLAVDRKRI--VLEFAPFKDLKCVFQH------YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNI-----GTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQT 5539
            W+ G++++  D  YL +E    + +K        + +SE+     +  I D ++ L+++W+  LT  +  G  +M  YV C  C             +E V   D+    L +    F    +H +     + +VP++ + D P  + +  S LE    ++++ G GG+G+V ++  Y+G+  AVK  +I   ++S +AP+  +LR               QE  +L   QHP IVSL+ +    +   LE AP   L  V         ++ L  +L Q+IAYQ+ SG+ +LH  NII+ D+K  N+LV+SL     IN+KL+DYGISR+    G +  +GTPGYQAPE+  R I Y    D+FS+G++L+ +       +GHH  +       G +  ++ +     + R+Q  + +C    PE RP A  +   +  P+F    Y+ P  +Q+
Sbjct:    1 WQEGLLVTF-DGGYLSVESSDVNWKKKKSGGIKIICQSEMRDFSAMAFITDHVNSLIDQWFPALTATESDGTPLMEQYVPCPVCEASWAQHADPNERSESVQYFDMEDCVLTAIERDFISCPRHPDLPVPLQELVPELFMTDFPARLFLENSKLEHTEGENSILGQGGSGTVIYQARYQGQPVAVKRFHIKKFKNSANAPADTMLRHLRAMDAMKNFSDFRQEASMLHALQHPCIVSLIGISIHPLCFALELAPLGSLNTVLSENAKDSSFMPLGHMLTQKIAYQIASGLAYLHKKNIIFCDLKSDNILVWSLSAKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPR-IVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIVKKLSKGIR-PVLGQPEEVQFHRLQALMMECWDTKPEKRPLALSVVSQMKDPTFATFMYMLPCGKQS 453

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Mouse
Match: Cdkl3 (cyclin-dependent kinase-like 3 [Source:MGI Symbol;Acc:MGI:2388268])

HSP 1 Score: 88.1965 bits (217), Expect = 6.256e-19
Identity = 64/190 (33.68%), Postives = 104/190 (54.74%), Query Frame = 2

Query: 4757 GVGGNGSVFKGYYK--GKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKR----IVLEFAPFKDLKCVFQHYIN-LSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQ--GTPGYQAPEVLERCISYKLPADIFSFGILL 5299
            G G  G+V K  +K  G+  A+K   +     +    ++  +EI  L++F+H ++V+L+ V R++    +V EF     L    QHY + L S  L++  +Q++  I++LH NNII+RDIK +N+LV     S     KL D+G +R LA  G V      T  Y+APE++ +  SY  P DI++ G ++
Sbjct:   11 GEGSYGTVMKCKHKDTGRIVAIK---IFYEKPEKSVNKIATREIKFLKQFRHENLVNLIEVFRQKKKIHLVFEFIDHTVLD-ELQHYCHGLESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILV-----SQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMI 191

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Mouse
Match: Cdkl3 (cyclin-dependent kinase-like 3 [Source:MGI Symbol;Acc:MGI:2388268])

HSP 1 Score: 91.6633 bits (226), Expect = 7.133e-19
Identity = 67/198 (33.84%), Postives = 108/198 (54.55%), Query Frame = 2

Query: 4757 GVGGNGSVFKGYYK--GKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKR----IVLEFAPFKDLKCVFQHYIN-LSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQ--GTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGH 5323
            G G  G+V K  +K  G+  A+K   +     +    ++  +EI  L++F+H ++V+L+ V R++    +V EF     L    QHY + L S  L++  +Q++  I++LH NNII+RDIK +N+LV     S     KL D+G +R LA  G V      T  Y+APE++ +  SY  P DI++ G ++  + T GH
Sbjct:   11 GEGSYGTVMKCKHKDTGRIVAIK---IFYEKPEKSVNKIATREIKFLKQFRHENLVNLIEVFRQKKKIHLVFEFIDHTVLD-ELQHYCHGLESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILV-----SQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMAT-GH 198

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. UniProt/SwissProt
Match: sp|Q5S006|LRRK2_MOUSE (Leucine-rich repeat serine/threonine-protein kinase 2 OS=Mus musculus OX=10090 GN=Lrrk2 PE=1 SV=2)

HSP 1 Score: 462.996 bits (1190), Expect = 2.028e-130
Identity = 357/1224 (29.17%), Postives = 618/1224 (50.49%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIP-KHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLN-LLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQN--GSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKL------WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCL------ECAEQVPLLDIASISLRSDHFFCTSKHQNQFRI--VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA--VDRKRIVLEFAPFKDLKCVFQH-YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVF------ESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFK---VLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDYIFATSGFVIYK------INLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLII--SFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKE---KLNINSK---SYSCRIMCMTIWSGDRYLCAGTGNGYLIIID 6376
            K+  I PEIG L +LT LD+S+N  L+S P+E+G  K   +  L  DGL+LN   KH+   A  ++I+++   RLK +V YN ++L+++G  G GKT++L  L++  K +      +  I+V  W +Q +  ++  D  L  WD +G++EF+  H  F++QRA YL V+D++K   E+  +KP L+N+K +A  +PV +VGTHLD   E  RK     +   +L   +  GFP I    FV+AT  +  +  L+  I+    +  I++  ++ +  P  Y++LE++     K +P   P++  K +  LV +H+L L++ EL  AV FL+  GV++HF D    L++LYF++P+W+C ++ + +T+ +++  +++  G IS  D      + F SK+ + F K  ++ Q  K+LE + +        +++PS L    P   L    N+  I R++   + P GFW RLI R+  ++      F +   E  L      WR G+ ++     Y ++  +    +    ++I+V     G  +L ++VD ID L+EEW+ GL + D+ G          L      E  +++ L ++   +   D      + +    I  + PD++L DLP +I++N  +LE   + + + G G  GSV++  Y+G+  AVK  N  +H+    S RLLRQE+ +L    HPS++SLLA  +  + +V+E A    L  + Q    +L+  L  RIA  V  G+++LH   IIYRD+K  NVL+F+L  ++ I  K+ADYGI++     G    +GTPG++APEV    + Y   AD++SFG+LL +I T G         P EF      GK  D + E+    WP ++  I KC K  P++RP +  +   +     + +     + +   +ECM      S    ++L  GN  K ++   D+ + +       +EV  +RIL + +       ES +  GTQ+G L   +  E    +T   + D++ C+   S     K    L++G A+G +       +++   +  L  L + D   T +  + + + ++   + +        + S D   FT  KLIE  ++     +  +  F+++    L +  + Y   +N  ++  +D +  +L   +DC   +KE   KLN  SK   SYS R+  + +   +  L  GTG G+++++D
Sbjct: 1256 KLKEIPPEIGCLENLTSLDVSYNLELRSFPNEMG--KLSKIWDLPLDGLHLNFDFKHVGCKA--KDIIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKMKKPELGMQGATVGIDVRDWSIQIR-GKRRKDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKARASSSPVILVGTHLDVSDEKQRKACISKITKELL---NKRGFPTIRDYHFVNATEESDALAKLRKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKAVPTEFPVINRKHLLQLVNEHQLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKVMAQILTV-KVDGCLKHPKGIISRRDV-----EKFLSKK-KRFPKNYMM-QYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISP-----FMLSGRERALRPNRMYWRQGIYLNWSPEAYCLVGSEVLDNRPESFLKITVPSCRKGCILLGRVVDHIDSLMEEWFPGLLEIDICGEGETLLKKWALYSFNDGEEHQKILLDELMKKAEEGDLLINPDQPRLTIPISQIAPDLILADLPRNIMLNNDELEFEEAPEFLLGDGSFGSVYRAAYEGEEVAVKIFN--KHT----SLRLLRQELVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLHDIWTTGSRIMEGLRFPNEFDELAIQGKLPDPVKEYGCAPWPMVEKLITKCLKENPQERPTSAQVFDILNSAELICLMRHILIPKNIIVECMVATNLNSKSATLWLGCGNTEKGQLSLFDLNTERYS----YEEVADSRILCLALVHLAAEKESWVVCGTQSGALLVINVEEETKRHTLEKMTDSVTCLHCNSLAKQSKQSNFLLVGTADGNLMI-FEDKAVKCKGAAPLKTLHIGDVS-TPLMCLSESLNSSERHITWGGCGTKVFSFSND---FTIQKLIETKTNQ----LFSYAAFSDSNIIALAVDTALYIAKKNSPVVEVWDKKTEKLCELIDCVHFLKEVMVKLNKESKHQLSYSGRVKALCL-QKNTALWIGTGGGHILLLD 2438

HSP 2 Score: 65.4698 bits (158), Expect = 8.563e-9
Identity = 53/168 (31.55%), Postives = 83/168 (49.40%), Query Frame = 1

Query: 2374 SLFKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKI--NEIGLNISEKSLHFLRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL 2871
            S  +HLT L+L +NS+ S P+   + ++ L  LDL  N+ T  P FV K   + NL+ S+N+I            L    K   L  +NLS N+ +    N   V ++L+ + +  N+I    S  S   L++LK ++L  N I  +   FLE C K++S +   N L
Sbjct: 1008 SHLEHLTKLELHQNSLTSFPQQLCETLKCLIHLDLHSNKFTSFPSFVLKMPRITNLDASRNDIG-------PTVVLDPAMKCPSLKQLNLSYNQLSSIPENLAQVVEKLEQLLLEGNKISGICSPLS---LKELKILNLSKNHIPSLPGDFLEACSKVESFSARMNFL 1165

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. UniProt/SwissProt
Match: sp|Q5S007|LRRK2_HUMAN (Leucine-rich repeat serine/threonine-protein kinase 2 OS=Homo sapiens OX=9606 GN=LRRK2 PE=1 SV=2)

HSP 1 Score: 458.759 bits (1179), Expect = 3.687e-129
Identity = 359/1226 (29.28%), Postives = 619/1226 (50.49%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIP-KHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLN-LLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQ-NGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKL------WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDL--HGNRIMNCYVRCL----ECAEQVPLLDIASISLRSDHFFCTSKHQNQFRI----VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA--VDRKRIVLEFAPFKDLKCVFQH-YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVF------ESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFK---VLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNI----FLIDDYIFATSGFVIY---KINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLII--SFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKE---KLNINSK---SYSCRIMCMTIWSGDRYLCAGTGNGYLIIID 6376
            K+  I PEIG L +LT LD+S+N  L+S P+E+G  K   +  L  D L+LN   KHI   A  ++I+++   RLK +V YN ++L+++G  G GKT++L  L++  K      + +  I+V  W +Q +  ++  D  L  WD +G++EF+  H  F++QRA YL V+D++K   E+  +KP L+N+K +A  +PV +VGTHLD   E  RK  C  M     +L +  GFP I    FV+AT  +  +  L+  I+    +  I++  ++ +  P  Y++LE++     K +P   P++  K +  LV +++L L++ EL  AV FL+  GV++HF D    L++LYF++P+W+C I+ + +T+          G IS  D      + F SK+ + F K  +  Q  K+LE + +        +++PS L    P   L    N+  I R++   + P GFW RLI R+  ++      + +   E  L      WR G+ ++     Y ++  +         ++I+V     G  +L Q+VD ID L+EEW+ GL + D+   G  ++  +        E  +++ L D+   +   D     +  Q +  I    + PD++L DLP +I++N  +LE   + + + G G  GSV++  Y+G+  AVK  N  +H+    S RLLRQE+ +L    HPS++SLLA  +  + +V+E A    L  + Q    +L+  L  RIA  V  G+++LH   IIYRD+K  NVL+F+L  ++ I  K+ADYGI++     G    +GTPG++APEV    + Y   AD++SFG+LL++I T G         P EF      GK  D + E+    WP ++  I +C K  P++RP +  +   +     V +     L +   +ECM    + S   +++L  G+  + ++  +D+    ++G +  +EV  +RIL + +       ES I  GTQ+G L   +  + K  +T   + D++ C+   S+    K    L++G A+G +         +D   ++    PL    + N+      + +   +T   V++      +   +  FT  KLIE  +S     +  +  F+++    +++  + Y   +N  ++  +D +  +L   +DC   ++E   K N  SK   SYS R+  + +   +  L  GTG G+++++D
Sbjct: 1256 KLKEIPPEIGCLENLTSLDVSYNLELRSFPNEMG--KLSKIWDLPLDELHLNFDFKHIGCKA--KDIIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGMQSATVGIDVKDWPIQIR-DKRKRDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKARASSSPVILVGTHLDVSDEKQRKA-C--MSKITKELLNKRGFPAIRDYHFVNATEESDALAKLRKTIINESLNFKIRDQLVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVRENQLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQILTVKVEGCPKHPKGIISRRDV-----EKFLSKKRK-FPKNYM-SQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISP-----YMLSGRERALRPNRMYWRQGIYLNWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDICGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGD--LLVNPDQPRLTIPISQIAPDLILADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFN--KHT----SLRLLRQELVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPNEFDELEIQGKLPDPVKEYGCAPWPMVEKLIKQCLKENPQERPTSAQVFDILNSAELVCLTRRILLPKNVIVECMVATHHNSRNASIWLGCGHTDRGQLSFLDL---NTEGYT-SEEVADSRILCLALVHLPVEKESWIVSGTQSGTLLVINTEDGKKRHTLEKMTDSVTCLYCNSFSKQSKQKNFLLVGTADGKLAI------FEDKTVKLKGAAPLKILNIGNVSTPLMCLSESTNSTERNVMWGGCGTKIFSFSNDFTIQKLIETRTSQ----LFSYAAFSDSNIITVVVDTALYIAKQNSPVVEVWDKKTEKLCGLIDCVHFLREVMVKENKESKHKMSYSGRVKTLCL-QKNTALWIGTGGGHILLLD 2438

HSP 2 Score: 66.2402 bits (160), Expect = 5.173e-9
Identity = 54/167 (32.34%), Postives = 88/167 (52.69%), Query Frame = 1

Query: 2380 FKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIK-QFCLSKTDKT-TLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGLNISEKSLHF-LRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL 2871
             +HL  L+L +N++ S P+   + ++ L  LDL  N+ T  P ++ K S + NL++S+N+I     L  T K  TLK F         NLS N+ +    N  DV ++L+ + +   G  IS       L++LK ++L  N I+ ++E FLE C K++S +   N L
Sbjct: 1010 LEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTVKCPTLKQF---------NLSYNQLSFVPENLTDVVEKLEQLILE--GNKISGICSPLRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFL 1165

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. UniProt/SwissProt
Match: sp|Q38SD2|LRRK1_HUMAN (Leucine-rich repeat serine/threonine-protein kinase 1 OS=Homo sapiens OX=9606 GN=LRRK1 PE=1 SV=3)

HSP 1 Score: 329.331 bits (843), Expect = 2.587e-89
Identity = 268/998 (26.85%), Postives = 476/998 (47.70%), Query Frame = 2

Query: 2864 INLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNL-NIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAV--DYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTP------GFPKIS----KIVFVDATNFNQTITNLKNKILTVLND--HTIQNDHLLFEKQPSSYLKLEE--LFQEALKTLPENCPILTEKEVKDLVVKHKL-DLND-EELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAP--TNLSENLNTSKISRIFAFSFLPTGFWPRLIARISV-LAKSFKHLFD-----------------------------ICKLEFKLWRTGVIISMEDSIYLILEG-----KKDTEKNLEIIEISVTKSEL-GIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLEC-------------AEQVPLLDIASISLRS--DHFFCTSKHQN---QFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSV-FKGYYKGKCCAVKYINVVEHSN--DAPSYRLLR---------------QEIDILRRFQHPSIVSLLAVDRKRI--VLEFAPFKDLKCVFQH------YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNI-----GTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQT 5539
            ++ + P +  L SL+ L + +NP L+ LP E+G L   NL  L  + L + N+P  I K    + +L Y   +L+ + +   ++++++G   +GK+++L +LQ +   P+  +  + I  + W++Q     +A     +   WDI G       ++CF + +A Y++V+++    E +  L+  L N++ +AP+A V +VGTHLD ++   R  +   + + +L LC +P      GFP I+      +   +    + +  L   +   + D   TI    L     P SYL L+E  L ++  ++  ++   LT+++++ LV +    D+ D E+L+ A+ FL   G ++HF DT   L NLYFL P W+   + +   +    +  +NG I   D   L     F+++TE        +Q  + L  +++    +N+  ++P  LP +    T+   +   + I R+F  SF+P GFW R IAR+ + LA+    LF+                             + + +   W+ G++++  D  YL +E      KK     ++I    V +SE+     +  I D ++ L+++W+  LT  +  G  +M  YV C  C             +E V   D+    L +    F    +H +     + +VP++ + D P  + +  S LE +  + ++ G GG+G+V ++  Y+G+  AVK  ++ +  N  + P+  +LR               QE  +L   QHP IV+L+ +    +   LE AP   L  V         +I L  +L Q+IAYQ+ SG+ +LH  NII+ D+K  N+LV+SL++   IN+KL+DYGISR+    G +  +GTPGYQAPE+  R I Y    D+FS+G++L+ +       +GHH  +       G +  ++ +     + R+Q  + +C    PE RP A  +   +  P+F    Y     +QT
Sbjct:  560 LDTVPPSVCLLKSLSELYLGNNPGLRELPPELGQLG--NLWQLDTEDLTISNVPAEIQKEGP-KAMLSYLRAQLRKAEKCKLMKMIIVGPPRQGKSTLLEILQ-TGRAPQVVHGEATIRTTKWELQRPAGSRAKVESVEFNVWDIGGPASMATVNQCFFTDKALYVVVWNLALGEEAVANLQFWLLNIEAKAPNAVVLVVGTHLDLIEAKFRVERIATLRAYVLALCRSPSGSRATGFPDITFKHLHEISCKSLEGQEGLRQLIFHVTCSMKDVGSTIGCQRLAGRLIPRSYLSLQEAVLAEQQRRSRDDDVQYLTDRQLEQLVEQTPDNDIKDYEDLQSAISFLIETGTLLHFPDTSHGLRNLYFLDPIWLSECLQRIFNIKGSRSVAKNGVIRAEDLRMLLVGTGFTQQTE--------EQYFQFLAKFEIALPVANDSYLLPHLLPSKPGLDTHGMRHPTANTIQRVFKMSFVPVGFWQRFIARMLISLAEMDLQLFENKKNTKSRNRKVTIYSFTGNQRNRCSTFRVKRNQTIYWQEGLLVTF-DGGYLSVESSDVNWKKKKSGGMKI----VCQSEVRDFSAMAFITDHVNSLIDQWFPALTATESDGTPLMEQYVPCPVCETAWAQHTDPSEKSEDVQYFDMEDCVLTAIERDFISCPRHPDLPVPLQELVPELFMTDFPARLFLENSKLEHSEDEGSVLGQGGSGTVIYRARYQGQPVAVKRFHIKKFKNFANVPADTMLRHLRATDAMKNFSEFRQEASMLHALQHPCIVALIGISIHPLCFALELAPLSSLNTVLSENARDSSFIPLGHMLTQKIAYQIASGLAYLHKKNIIFCDLKSDNILVWSLDVKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPR-IVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIAKKLSKGIR-PVLGQPEEVQFRRLQALMMECWDTKPEKRPLALSVVSQMKDPTFATFMYELCCGKQT 1538

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. UniProt/SwissProt
Match: sp|Q3UHC2|LRRK1_MOUSE (Leucine-rich repeat serine/threonine-protein kinase 1 OS=Mus musculus OX=10090 GN=Lrrk1 PE=1 SV=1)

HSP 1 Score: 327.02 bits (837), Expect = 1.437e-88
Identity = 267/994 (26.86%), Postives = 476/994 (47.89%), Query Frame = 2

Query: 2864 INLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNL-NIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAV--DYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTP------GFPKIS--KIVFVDATNF--NQTITNLKNKILTVLND--HTIQNDHLLFEKQPSSYLKLEE--LFQEALKTLPENCPILTEKEVKDLVVKHKL-DLND-EELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAP--TNLSENLNTSKISRIFAFSFLPTGFWPRLIARISV-LAKSFKHLFD-----------------------------ICKLEFKLWRTGVIISMEDSIYLILEGKK-DTEKNLEIIEISVTKSEL-GIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLEC-------------AEQVPLLDIASISLRS--DHFFCTSKHQN---QFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSV-FKGYYKGKCCAVK--YINVVEHSNDAPSYRLLR---------------QEIDILRRFQHPSIVSLLAVDRKRI--VLEFAPFKDLKCVFQH------YINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNI-----GTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQT 5539
            ++ + P +  L +L+ L + +NP L+ LP E+G L   NL  L  + LN+ N+P  + K    +  L +   +L+ + +   ++++++G   +GK+++L +LQ +   P+  +  + I  + W++Q     KA     +   WDI G       ++CF + +A Y++V+++    E +  L+  L N++ +AP+A V +VGTHLD ++   R  +   + + +L LC +P      GFP I+   +  +   N    + +  L   +   + D   TI    L     P SY+ L+E  L ++  ++L +    LT++++  LV +    D+ D E+L+ A+ FL   G ++HF DT   L NLYFL P W+   + +   +    +  +NG I   D   L     F+++TE        +Q  + L  +++    +N+  ++P  LP +    T+   +   + I R+F  SF+P GFW R IAR+ + LA+    LF+                             + + +   W+ G++++  D  YL +E    + +K        + +SE+     +  I D ++ L+++W+  LT  +  G  +M  YV C  C             +E V   D+    L +    F    +H +     + +VP++ + D P  + +  S LE    ++++ G GG+G+V ++  Y+G+  AVK  +I   ++S +AP+  +LR               QE  +L   QHP IVSL+ +    +   LE AP   L  V         ++ L  +L Q+IAYQ+ SG+ +LH  NII+ D+K  N+LV+SL     IN+KL+DYGISR+    G +  +GTPGYQAPE+  R I Y    D+FS+G++L+ +       +GHH  +       G +  ++ +     + R+Q  + +C    PE RP A  +   +  P+F    Y+ P  +Q+
Sbjct:  560 LDAVPPSVCLLKNLSELYLGNNPGLRELPPELGQLG--NLWQLDIEDLNISNVPAEVRKEGP-KATLSFLRAQLRKAEKCKLMKMILVGPPRQGKSTLLEILQ-TGKAPQLAHSEATIRTTKWELQRPAGSKAKVESVEFNVWDIGGPASMATVNQCFFTDKALYVVVWNLALGEEAVANLQFWLLNIEAKAPNAVVLVVGTHLDLIEAKFRVERIATLRAYVLALCRSPSGSRATGFPDITFKHLHEISCKNLEGQEGLRQLIFHVTCNMKDVGSTIGCQKLAGRLIPRSYISLQEAVLAEQQRRSLGDQVQYLTDRQLDQLVEQTPGNDIKDYEDLQSAISFLIETGTLLHFPDTSHGLRNLYFLDPIWLSECLQRIFNIKGSRSVAKNGVIQAEDLRMLLVGTGFTQQTE--------EQYFQFLAKFEIALPVANDSYLLPHLLPSKPGLDTHSMRHPMANTIQRVFKMSFVPVGFWQRFIARMLISLAEMDLQLFENKKNTKSRNRKVTIYSFTGSQRNRCSTFRVRRNQTIYWQEGLLVTF-DGGYLSVESSDVNWKKKKSGGIKIICQSEMRDFSAMAFITDHVNSLIDQWFPALTATESDGTPLMEQYVPCPVCEASWAQHADPNERSESVQYFDMEDCVLTAIERDFISCPRHPDLPVPLQELVPELFMTDFPARLFLENSKLEHTEGENSILGQGGSGTVIYQARYQGQPVAVKRFHIKKFKNSANAPADTMLRHLRAMDAMKNFSDFRQEASMLHALQHPCIVSLIGISIHPLCFALELAPLGSLNTVLSENAKDSSFMPLGHMLTQKIAYQIASGLAYLHKKNIIFCDLKSDNILVWSLSAKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPR-IVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIVKKLSKGIR-PVLGQPEEVQFHRLQALMMECWDTKPEKRPLALSVVSQMKDPTFATFMYMLPCGKQS 1538

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. UniProt/SwissProt
Match: sp|Q9TZM3|LRK1_CAEEL (Leucine-rich repeat serine/threonine-protein kinase 1 OS=Caenorhabditis elegans OX=6239 GN=lrk-1 PE=1 SV=6)

HSP 1 Score: 210.305 bits (534), Expect = 7.722e-53
Identity = 265/1122 (23.62%), Postives = 462/1122 (41.18%), Query Frame = 2

Query: 2879 PEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHIS---KNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLL--QGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVD---YKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENN------------RKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQE-ALKTLPENCP-ILTEKEVKDLVVKHKLD------LNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLV---KQCLKVLELYDVVFRNSNNEIIIPSKLPIQ----------------------------------------APTNL----SENL-------NTSKISRIFAFSFLPTGFWPRLIARI---SVLAKSFKHLF-----------DI----CKLEFKLWRTGV-----------------IISMEDSIYLILEGK-KDTEKNLE---------IIEISV------------------TKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLH---GNRIMNCYVRCLECAE------------------------QVPLL------------DIASISLRSDHFF----------------CTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYK---GKCCAVKYINVVEHSNDAP---------------------------SYRLLRQEIDILRRFQHPSIVSLLAVDR--KRIVLEFAPFKDLKCVFQHY----INLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVL--VFSLELSSKINV--KLADYGISRELAPFGFVIP-QGTPGYQAPEVLE--RCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRA----GKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFV 5503
            P++  L+ L++L++S N  +K LP + G+L    L SL   G +L  P       +N +  EI+ Y    L+ S  Y+ LRL++LG  G GK+ + + L  +  + +   ++++  I  + WK ++K S+   +      +  D  GQ E+   H+ FLS+R+  L+++ IT   E + +L   L N+  +AP++ V +VGT+LD++  N+            +K + R+M ++  K     G P+I  ++ +++T+ N  +  L N I     +  +  +  + ++ PSSY+ L ++ +E  ++   E  P ++T +  ++ V K  +        +D E   A  FLH+CG +V F D    L +L F+ P W+   +   + +            S N    L      +  T +FK   L+    Q L +L  +++       +++IPS LP +                                        +PT+     SE++       +   + RI+A +++P+GFW RL+ RI     +  + + +F           DI     K E+ +W+TG+                 +  + D  Y  ++ + KD +K            I+E+ V                  T  E   ++L  I D +D L+E+WY  L    +H   G+ +++ YV C +C                          ++P+             DI+       H F                C S      R + PD V  D+ + + I+P  L+    +  M G G  G VF+   +   G+ C V    ++E  +  P                           +Y   RQE+ +L R +HP+++ L+ V      +V+E AP   L  +   +      LS  +++  A QV   +++LH  +IIYRD+K +NVL   F    S + +V  KL DYGISR + P G      GT G+ APE++       Y    D FSFG+ L+ + T+   P E   H +     G +  L+        P M D +  C    PE RP++  +  F   P F 
Sbjct:  899 PDVARLTLLSMLNLSGNTAIKELPPDYGMLS--RLWSLSLKGCSLKEPLESMVNVENCKTVEIVAYLKTILEESKTYHHLRLMILGSDGVGKSVIWDALCKEAVQKRQPIHSETGVIRQAEWKFEAKRSKGDKNLGPVGFSVIDFGGQREYHSTHQYFLSKRSLNLVLWKITDGDEALAQLDTWLVNIHARAPNSTVILVGTNLDQVASNSSKFGPGYIDIMEQKVRTRYMVADADK----SGLPRIVDVILINSTSRND-VKALLNTIYRTAWEVRMGKERAMEQQIPSSYIALMKVTKELGVEFRKEGQPAVMTVEAYRERVKKRMISKFGRPFRDDIEFYAACTFLHDCGELVRFEDA--TLRDLIFVDPLWLAEFLTSVVILR-----------SPNLPAGLLSTDAINPHTRSFKSGALLMLKTQLLDLLHKFELALATQPRQLLIPSLLPDEYRLRSDFLASAVKIRMKMSQWNVRCPSPAGSPTKSPLRRTSPTDQNGVGSEDVMLQFTYDDDQLLRRIYALAYIPSGFWSRLVTRIVGDKNVCAAIESIFMTTSADRAKIADIATKHAKAEWVVWQTGIELHVKGHSLFTLKQFLPLAEVRDIDYSAIDMRAKDEQKRWRTWNQPSHRPIVEMVVNSLSISAASQHGRKLSMKTDVEGRSRLLAMISDLLDTLLEDWYPALGTRFVHSSEGDLLVSRYVLCPQCVRDAERNGSRSRTSSSASHRRSQDDGELPITSSSHMKGSRTTGDISKCRGGVVHCFVIEECMLAGREYNWVECPSHGGLHMRELAPDTVFADIENALTIHPDQLK----RSRMLGRGAFGFVFRATVRQPNGELCEVAQ-KMLEPVDPGPGGRPSALAAYKAAADKWKRDSMEFACRAYCTSRQELSLLSRMKHPNVIGLVGVCTFPLSLVVELAPLGALNQLLGSHRKAGTKLSLGVIKESAVQVARALEYLHSAHIIYRDLKSENVLGWRFPAPFSPQTDVLLKLGDYGISRSVLPSGGAKGFGGTEGFMAPEIVRFNGEEEYTQKVDCFSFGMFLYELLTL-KFPFESEEHVKERMLDGARPVLLPHELLLPTP-MLDLLVHCWSAHPESRPSSSQLVGFCAAPEFT 1993

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. TrEMBL
Match: A0A516IJV2 (Leucine-rich repeat serine/threonine-protein kinase 2-like protein (Fragment) OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 1467.21 bits (3797), Expect = 0.000e+0
Identity = 721/1147 (62.86%), Postives = 894/1147 (77.94%), Query Frame = 2

Query: 3281 WDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFK---DHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECAEQVPLLDIASISLRSDHFFCTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVFESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDYIFATSGFVIYKINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKEKLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIIDQEINYTVVLSLFKNHIICIQHSKLHNKHDKPDKEIVSGPTPEKPDVTDHLINCT-ETFESSAENTGLIIVGNGYKSIEED-FDGAVLIVLSDDISNISRQLEEHINSRNHIL 6706
            WDI+ Q+     HEC+LSQRAFY++VFD+TKE EEI+ L+PLLWN+K QAPHAP+ IVGTHLD +K N R  +C  + + + KLC TPG PKI+   FVD+++ N++IT LKNKI +VL  H   ND  L EKQPS YLKL E+ ++ LKTLP NC ILTEKEVK+L+ KHKL+LND ELKLAVQFLH+ G+I HFNDT ENLNNLYFLKPQWICS+I KTI+M  LN F  NG I+L +F++LFK   D   S  T N   +  + QCLKVLE Y+V+F++ N+E+IIPSKLPI  P  LSE LN+SKISRI+ F FLP GFWPRL+ +ISVL+KSF HLFD+ KLE   WRTG+IISME SI+L+LEGK++   N EIIEISVTKSELGIKILV I+DCI+V+++EWY GLTDDDL GN+++ CY  C +C  ++PL+DI  +S++S+ F C   H    RI+ PD+V GDLP+D+L+ PS+LEV  SK+N+ G+GGNG V+KG+YKG  CAVKYIN +++SN+ P+YRLLRQEIDILRRFQHPS+VS+LA DR++IVLEFAP KDLK + Q Y NLS  LLQRIA+QVISGIQ+LHFN IIYRDIKMQNVLVFSLELSS INVK+ADYGISRE+ P+GF+IPQGTPGYQAPEVLER  SYKLPADI+SFGILLFNI T G HPA+ +AHWRAGKQI+LISE+ SN WPRMQ+CI+KCT LVPEDRPNA++IS FI CP+F+ IK V PLT+QTRIECM +M+N +  L+VF+ANGN+ KQEVR IDI SG SKGK F +  +SNRILSMMVF  +IFLGT NG+LW Y+H EN   ++++   D+I+ M++ +  D   +LM+GL NG I YKL + SI DIN     ++ LS+APVTN+ L +D IFATSGF IYKI  +     F   K++E+DS++QD+LIKCF PF EN NG+L +  YFTIRN+ LIYN+DDQG QLKP ++CK+LIKEKLNI +K YS RIMC+TIWSG RY+CAGTGNG+L+IIDQ+IN+T++LSLFKN II +Q  KLH      +KE+       K +V D L +   E+     +NT L++VGNGYKSI ED F GAVLI LSDDIS +SR+L+EHI SRN IL
Sbjct:    1 WDITNQEGLNSFHECYLSQRAFYIIVFDMTKEIEEINILRPLLWNVKSQAPHAPILIVGTHLDILKSNERSNRCLFLRNTLKKLCITPGLPKIADFEFVDSSSPNRSITALKNKIGSVLCSHRFINDQTLIEKQPSYYLKLSEILKDCLKTLPANCSILTEKEVKNLLTKHKLNLNDNELKLAVQFLHDSGIIAHFNDTFENLNNLYFLKPQWICSMISKTISMPSLNIFTHNGIITLGEFITLFKTNTDFLLSGNTSN---KIQIVQCLKVLEKYNVIFQSLNDEVIIPSKLPINPPKKLSECLNSSKISRIYEFLFLPAGFWPRLLTKISVLSKSFDHLFDVYKLELNSWRTGMIISMEQSIHLVLEGKQEIVNNKEIIEISVTKSELGIKILVYIIDCIEVIIDEWYPGLTDDDLQGNKVITCYAVCPDCNTKIPLIDIVKVSMKSE-FICKFGHHTLIRIIAPDMVFGDLPNDLLVIPSELEVVNSKENLIGIGGNGCVYKGFYKGINCAVKYINNIDYSNEQPAYRLLRQEIDILRRFQHPSLVSMLAADREKIVLEFAPMKDLKYILQTYKNLSKCLLQRIAFQVISGIQYLHFNYIIYRDIKMQNVLVFSLELSSPINVKIADYGISREVCPWGFIIPQGTPGYQAPEVLERSTSYKLPADIYSFGILLFNIATRGRHPADLKAHWRAGKQIELISENQSNIWPRMQNCINKCTYLVPEDRPNAKEISDFIRCPTFMTIKSVLPLTQQTRIECMVSMLNSNKTLDVFIANGNQIKQEVRCIDIISGNSKGKPFLQNNNSNRILSMMVFSDVIFLGTLNGELWIYNHKENLILSSHIKFQDSIISMLVINAPDKSLILMLGLINGIINYKLNFISIFDINIGDFEEIKLSEAPVTNLHLTNDLIFATSGFEIYKICFNQMNGNFEYNKVLELDSNNQDQLIKCFYPFIENINGNLTVQLYFTIRNDCLIYNYDDQGNQLKPEINCKKLIKEKLNITTKRYSSRIMCLTIWSGCRYICAGTGNGFLVIIDQKINHTLILSLFKNPIITVQVCKLHENPLGVNKEMNKAEINXKSEVIDRLSSFKDESINIHNQNTSLLVVGNGYKSIGEDSFKGAVLIALSDDISKVSRRLDEHIKSRNDIL 1143

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. TrEMBL
Match: R7VFD9 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_224870 PE=4 SV=1)

HSP 1 Score: 548.895 bits (1413), Expect = 1.944e-159
Identity = 390/1257 (31.03%), Postives = 653/1257 (51.95%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLV-----FDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDAT--NFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLF----KDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKH-------LFDICKLEFKLWRTGVIIS-MEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECAEQVP----LLDIASISLRSDHFFCTSKHQN--QFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRK--RIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHP--AEFRAHWRAG---KQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDI-------KSGQSKGKSFCKEVDSNRILSMM-VFESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVM-----KSYVDYFKVLMMGLANGTIYYKLGYTSIQDINSEILSK-------LPLSDAPVTNIFLIDDYIFATSGFVIYKINLS-IDTERFTAVKLIEIDSSDQ-DRLIK--CFC---PFTENTNGDLIISFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKEKLNIN-SKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIIDQEINYTV-VLSLFKNHIICIQHSKL 6448
            K+  +  E+G LS+L+ L++SHNP+LK+LPDE G L    L  L  +GL L +  +I  + +  ++++Y +++LK SVEYN ++++V+G  GRGK++++  L               + +  WK   K   + V   L+CWD +GQ+EF+  H+CFL  +A Y++      F I+    E+  LKP L N++  AP  PV +VGTH+DK+           M S+I  L  +PGFP +      + +       ++ L+  I T +N   +    ++ +  P+SYLKL++LF   LKT+  + PI+ E  VK +V   KLDL  EEL+ A++FLH  GV++H+ D+  +LN+LY L P+W+C ++ + I +  +N F+    +   D L L     K H   +    F  E  + Q LK+LE ++V    +++E++IPSKLP + P  +    + + I R +   ++P GFW RL+ R+ VL++S+         + ++   +   W+TGVI+S ++D  + +    K     LE +EI+V  S  G K+L QIVD ID L+EEW+ GL      G+ ++ C   C++C    P    L ++   S  SD   C  KH       ++ PD V GDL     ++ S+L    S +N+ G G  G V+KG+YKG   A+K   + +   D P ++L+RQE  IL+   HPSI+ L+ V  +  R+V+E APF  L  V ++   L+  +  RIAYQ+  G+Q+LH   I+YRD+K  N+LVF+L   + INVK++DYGI++  +PFG    +GTPGY+APEV+ +  +Y   AD+FS+GI+L+ I T G  P   +FR         + I  IS    + W  M++ I +C +  P+ RP +  I + +     ++++  +PL +    +C+   M       V+++ G +   ++  I++       K  +SKG  F   +DS RI +M+ V +  + LGTQ+G++W YD   ++  +T     D+++ ++      K+ VDY   L++GLANG +       SI+   S +L         L  S A    +  + D +     F I       I     + ++L+ +++  Q D  IK    C   P        L  S +   R   ++  +      LK ++D   ++K +  ++ S++Y+ RI  M  +  D  L  G  NG + ++D+   + + V+  +   + CI   ++
Sbjct:  366 KLKKLPREMGELSALSSLNLSHNPDLKTLPDEFGKLS--RLWELNLEGLKLKLNPNIV-HGRTTDLIRYLHEKLKKSVEYNRMKMMVVGYGGRGKSTLVKRLMRQIPTADPPPTVGFV-IKEWKFPMKKGSRYVGQTLSCWDFAGQEEFYSQHQCFLFDKALYVVSCLQSEFGIS----ELQTLKPWLMNIQAHAPKCPVIVVGTHIDKVPREKLSETIHRMHSSIYSLFRSPGFPSLKNAFLAEVSCGEVACGLSQLRLLIRTAVNK--LNGRPVMGQMIPASYLKLQQLFAFELKTVNPSLPIINEHRVKSMVKDCKLDLEGEELRQAIRFLHETGVVLHYEDSSSHLNDLYILDPEWLCRMMAQVIAVREINPFVDQNGVLKKDVLKLLFNGKKIHHHGRRHFTFPPER-INQYLKLLERFEVALPLNDHELLIPSKLPDKIPAGIQLPKDEALIRRHYNMRYIPVGFWSRLLIRLLVLSRSWLSQNGRGLGIEEVEPQQINFWKTGVIVSFVQDLTFTVHSFSK--RARLECVEIAVPPSPHGAKLLGQIVDIIDSLIEEWFPGLLGVSPTGHSLVQCCAPCIQCPRLRPHVFSLNELLKQSETSDEIRC-PKHDALVPLALLAPDAVFGDLERRYTLDVSELHSLVSPENLLGDGSFGCVYKGWYKGSKVAIK---MYQPFGDVPVHKLIRQEATILQSLHHPSILHLIGVASRPWRLVMELAPFGSLDHVLKNREPLTRHMQHRIAYQIADGLQYLHSQKIVYRDLKPGNILVFNLAPGATINVKISDYGIAQVASPFGLSSAEGTPGYRAPEVV-KGQTYLFQADVFSYGIVLYQILTSGQSPYSGQFRFELDNAVHSEVIKPISTKGFSPWTDMEELIWQCVRQNPDKRPTSSQIVEMLKDGEVLSLRRAFPLCKTNDADCIAHQMRADGGQEVWISCGEEGNSQLSWINMDETLNGFKEQRSKGTMF---IDS-RISTMIRVGDDHMVLGTQSGRIWVYDSDSHQRSHTLEPAEDSVVSLLHYTHRNKTDVDY---LLVGLANGRVVVYPTTRSIRGKRSAMLKNITSPFCVLQSSSAQPLAVLQVGDDLQPVLCFEIGSTQRGRIYVTAGSLIQLLRVETKIQLDENIKWDTLCGGQPGNIQFMSRLNRSLHVAKRGSCVLECWSTYRRVLKNSLDLSTVLKPEDPVSPSETYAARITSMHSFDMD-MLWLGCANGRIFVVDKGAYHVIRVIHRYTGPVRCIDQVRM 1596

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. TrEMBL
Match: A0A2T7NTI5 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_14970 PE=4 SV=1)

HSP 1 Score: 556.599 bits (1433), Expect = 5.400e-158
Identity = 417/1337 (31.19%), Postives = 692/1337 (51.76%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXX-XXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLP-ENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFI-QNGSISLNDFLSLFKDHFFSKETEN--FKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLSENLNTSK-ISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKL-----EFKLWRTGVIISMEDSIYLILEG-KKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTD-DDLHGNRIMNCYVRCLECAEQVPLL----DIASISLRSDHFFCTSKHQNQFRI--VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKR---IVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHP---AEFR----AHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTM-MNESNILNVFLANG-NKFKQ------------EVRSIDIKSGQSKGKSFCKEVDSNRILSMM-VFESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMGLANGTI-YYKLGYTSIQDINSEILSKLPLSDAPVTNIF--LIDDYIFATSGFVIYKINLSIDTERFTAV-KLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKEKLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIIDQEINYTVVLSLFKNHIICIQHSKLHNKHDKPDKE-------IVSGPTPEK--PDVTDHLINCTETFESSAENT-GLIIVGNGYKSIEEDFDGAVLIVLSDDISNISRQLEEHINSRN 6697
            KI+ +  EIG+LSSL  LDISHN  L +LPD++G  +   L  +  DGLNL+I       A++RE+  Y ++RLK + +Y  ++L+V+G  GRGKTS+L+ L+    +   +   +  + V  WK + + + K + Y L+ WD +GQ++F+  H+CFLS R  YL V+DI+  T+E+ +LKP L N+  +AP  PV IVGTH DKM   +R       +  +  L S PGFP+I     VD T  +  +  L+ KIL+V++++ ++   ++ +K P+SY+KL E+  E  +T+  ++ P+L   ++  ++    L+L+++ELK AV FLH  GV++H+++T   + + YF+ P W+C ++ + +T+  +N FI ++G +  N    LF     + + EN       ++ Q L++LE +++    +  E++IP +LP   P      L+    + R ++  F+P GFW RL+ R+ V  +S K + ++  L     E   W+ G+ +  +   + +L+G + DTE+    + ++V  S  G+++L  +VD ID LV+EWY GLT  + L G  ++  +V C  C  + P L    D+ S S RSD   C  +H     +  + PD++L D+     +     E   S +N+ G GG GSV+K  Y+G+  A K  + +    D   +++LRQE  I+RR +HPS+VSL+AV R     +++EFAP + L  V    I+LS  +  +I  QV  G+ +LH   I+YRD+K  NVL+FSL   + +N K++DYGIS+  A  G V  +GT  ++APEV+ R  +Y   AD+FSFGIL++ + T G HP    EF+      +   + +  + +     W  MQD +++C   VP+ RP +E + + +       ++ V P++  T +ECM     ++ + + +++A+G N++ Q            E+ + +       G  F       RIL ++ V +  + LGTQ G++W ++   N   +++  L D++LC+ + +  D   VL  GLANG I  Y L         + I  +L  S  P+  I   ++D  +  + G  I    + +D+    AV K+I  D    D       P      G L+   Y + RN + +  +D Q  + K  +D  ++ K       +    RI  M +   ++ L  GTG G++ +ID        L++   H   I+ S L  +   P K        I+SG    K  PDV           E   EN  G + V       E D+   VL  L+D+ SN  RQL E + S+N
Sbjct: 1267 KISELPKEIGHLSSLQSLDISHNKLLTTLPDDLG--RCSCLWEMPLDGLNLDI--DFKAGARVRELRMYLHNRLKKAQDYYRMKLMVVGYGGRGKTSLLHALKKKVRQSGESPPVTVGVIVDEWKFERQRNNKTITYTLSTWDFAGQEDFYSTHQCFLSNRTLYLGVYDISLGTDEVDRLKPWLANIHARAPGCPVIIVGTHYDKMAPEDRAKIVSEFDIKLKDLMSKPGFPEIKCSAMVDLTRESNEMDQLRKKILSVIDEYKVRGQPVMGQKVPASYVKLAEVLSEEARTMTVKDFPVLRHNQLMRIIHNENLELDEDELKQAVSFLHESGVLLHYDETALQMRDFYFINPGWLCRMMAQVVTVPEINPFIKRDGIMKRNSAYMLFAGKAIAGDKENSFIFPPNMIPQYLRLLEKFEIALPRNEEELLIPCRLPSIRPQFQVPQLDRKDMVFRFYSMPFVPIGFWSRLLTRLIVFTQS-KFMENVLMLGSKPAEVHCWQEGLFVIWKQDTFFMLDGCRGDTEE----VHVTVPSSPPGVRLLGYVVDHIDSLVDEWYPGLTSIEPLLGRELLQKFVPCTTCTGKEPHLFLFSDLVSESERSDTVVC-PQHAGDVSLSQLAPDVMLTDVESHFRLEVDKFEFKNSPENLLGDGGFGSVYKAVYRGQTVATKVFSAI---GDTHPHKMLRQEAIIMRRLKHPSVVSLVAVARTPQHLMLMEFAPGRSLAHVLNSQISLSRTIQHKILLQVAEGMHYLHQLMIVYRDMKPDNVLIFSLSPDAVVNAKISDYGISQFTALSGLVAQEGTYSFRAPEVI-RGETYSFQADVFSFGILMYLVLTGGQHPFEELEFKNERDKSFADNRPVPPLIQRGCPPWADMQDLMNQCMHQVPDYRPLSETLCQRLNTAELFCLREVLPVSVGTTVECMAYQEFDDGHNMRLWVASGDNEYMQLTWFSLLDYTDEELTNRNRHKPNGMGTMF----RDGRILCVLPVNKEYVLLGTQAGKIWVFN-TRNDLLHSSPPLQDSVLCLNIITRNDDSLVL-AGLANGKIALYPLSEILQSPQMNPIEIRLGESYEPICCILHNIVDRRLVVSCGTRI----IVMDSREGVAVEKMITTD----DNSGPASKPILTMACGRLL---YLSRRNMTEVEAWDLQRERRKMIMDLSDVFK------LQKKESRITSMALHE-NKVLWVGTGGGHVAMID--TTAWTALTITDRHTASIR-SLLSVRLTGPGKYGSSSTSIILSGGLGFKTGPDV-----------ELERENQYGCVAVW------EADYP-QVLKTLADN-SNKRRQLLEKLQSQN 2543

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. TrEMBL
Match: A0A2R2MN78 (leucine-rich repeat serine/threonine-protein kinase 2-like isoform X2 OS=Lingula unguis OX=7574 GN=LOC106175217 PE=4 SV=1)

HSP 1 Score: 532.332 bits (1370), Expect = 1.881e-152
Identity = 380/1246 (30.50%), Postives = 633/1246 (50.80%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFI-QNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAP----TNLSENLNTS------KISRIFAFSFLPTGFWPRLIARISVLAK--SFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLEC----AEQVPLLDIASISLRSDHFFCTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA--VDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSK--INVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAE---FRAHWRAG------------KQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFK-QEVRSIDIKSGQSKGKSFCKEVDS-----NRILSM-MVFESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDA--PVTNIFLIDD----YIFATSGFVIYKINLSIDTERFTAVKLIEID-SSDQDRLIKCFCPFTENTNGDLIIS---FYFTIRNESLIYNFDDQGIQLKPAVDCKELIKE-KLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIID-QEINYTVVLSLFKNHIICI 6433
            +++ +  EIG LSSLT LDI HN ++ +LPDE+G L    L  L  D L L++P+ I K  + R+++ Y  +RL+++ E+  ++++V+G  GRGK++++  L     +P  +  +  ++V  W++++    K   Y L+ WD +GQ+EF+  H+CFLS R+ YL+V+++     E+  L+P L N+K +APH+PV IVGTH D + ++ R+ + + M S I +LC  PGFP +  ++ ++    +  I  L++KI   +    I+   ++ +K P S++KLEEL     K      P++  + ++ ++    LDL++EELK AV+FLH  GV++H+ D  + L N YFL PQW+  ++ + IT+  +N FI + G +   D   LF    F K   NF   +L+ Q L++LE ++++    N+E +IP +LP + P      LS+ ++++      +I R +   ++P GFW RLIAR+ V     S  +       E   W  G+ +   + +Y ++E         E++ I+V  S++G  +L  IVD ID L+EEWY GLT+    G  ++   V C +C         L D+ S S       C +        + PD++  DL D   I+P     N S + + G GG GSV++  YK K  AVK  N V    D   ++++RQE+ I+R   HPS++S++A  V+ + I+LE AP   L  + +    L     QRIA QV  G+ +LH N IIYRD+K +N+L+F+L L     IN K++DYGISR  AP G    +GTPGY+APEV+ R   Y   AD++SFG+ L+ + T G HP +   FR                  K   +        WP MQD I+ C K VPE+RP A +I + +     ++++   P+++   +ECM T+ ++ + + +++ +G      ++  + +     K       +       +RIL +  +  S + +G  +G +W YD    + ++    LPD++LCM           + +GLA+G +        + D  +E    L   ++  P+  I         YI   S  V+    L  DT R       EID +++Q R I C           +++S    Y     E+ +  +D     LK  +D  + + E   ++      CR+  + +      L  GTG G L+I+D   +    VL   +  + C+
Sbjct:  568 ELSEVPKEIGLLSSLTSLDIGHN-SILTLPDEMGRLN--KLWELRYDRLELDLPQAILK-GRTRDLIVYLSERLRNASEHYRMKMMVVGYAGRGKSTLIRTLM-KLPQPDKSIATVGVQVKDWELRTG-RRKPPHYTLSTWDFAGQEEFYNTHQCFLSNRSLYLVVYNLQIGPSEVETLRPWLLNIKARAPHSPVIIVGTHKDGLAKDEREQKIKEMRSLISELCCKPGFPDVKAVIELNCCYESSDIERLRDKIKEAVEGFKIKGQPVMGQKIPESFIKLEELVSYEAKAR-ATLPVIKAQTLRKIIKDANLDLDNEELKQAVRFLHESGVMLHYEDASQQLENFYFLDPQWLGRMMAQVITVREINPFIDEKGILRKTDINLLFNGKRFEK--FNFPT-SLIPQYLRLLEKFEIILPRGNDEFLIPCRLPAKKPPISFPGLSDVVDSNGNRKPIQIQRQYEMPYIPLGFWSRLIARLVVFIPKMSANNPDSGVVPETVYWIEGICVYWSELLYFMIE--PFCRDGHEVVVITVPLSKMGTSVLGHIVDHIDTLIEEWYPGLTEKSPTGLELVQRIVPCSQCIGPSIHHFVLDDLVSQSELDASMNCPNCGPVPLSRLAPDVIFADLEDHFQIDPQSFFFNKSPEYLLGDGGFGSVYRAKYKNKEVAVKVFNAV---GDIHPHKMMRQEVTIIRELNHPSLISMVAVGVNPRAILLEVAPLGSLGSLLKTR-TLGRAEQQRIAMQVAEGMAYLHHNMIIYRDMKPENILIFNLALGPNVVINAKISDYGISRFAAPCGLRASEGTPGYRAPEVI-RGEVYGAQADMYSFGMTLYELVTNGRHPYDDLSFRNQLDEAVLMKRPINPITTKLDPMTGRPCCQPWPDMQDVIYLCLKYVPEERPTAAEIHEKLERCDLLSLRNFLPISKNMTVECM-TLRHDGDGMELWVGSGGSEDCAQLSWVSLTENDPKILDLTLSLQGKFHPDSRILCLTTIGSSCVLIGCLSGHIWVYDAYTREHKHKLPRLPDSVLCMHFHQNQSGDAQVYVGLASGQLAIFDANNVLTDAFAEPSYTLRFGESSEPIRCIVPHTQSKTLYIGCGSKIVM----LLPDTWRDIPQ---EIDTATEQSRGIICA----------MVVSRKYLYLAKMQEATVEAWDLNKQVLKHTIDIYKTVSEFDPSMKLSRGDCRVTSLLL-QNTHTLWVGTGEGLLVILDTNSLRPCAVLKRHRTAVRCM 1777

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. TrEMBL
Match: A0A2R2MNR6 (leucine-rich repeat serine/threonine-protein kinase 2-like isoform X1 OS=Lingula unguis OX=7574 GN=LOC106175217 PE=4 SV=1)

HSP 1 Score: 532.717 bits (1371), Expect = 4.226e-152
Identity = 380/1246 (30.50%), Postives = 633/1246 (50.80%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFI-QNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAP----TNLSENLNTS------KISRIFAFSFLPTGFWPRLIARISVLAK--SFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLEC----AEQVPLLDIASISLRSDHFFCTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLA--VDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSK--INVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAE---FRAHWRAG------------KQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFK-QEVRSIDIKSGQSKGKSFCKEVDS-----NRILSM-MVFESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDA--PVTNIFLIDD----YIFATSGFVIYKINLSIDTERFTAVKLIEID-SSDQDRLIKCFCPFTENTNGDLIIS---FYFTIRNESLIYNFDDQGIQLKPAVDCKELIKE-KLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIID-QEINYTVVLSLFKNHIICI 6433
            +++ +  EIG LSSLT LDI HN ++ +LPDE+G L    L  L  D L L++P+ I K  + R+++ Y  +RL+++ E+  ++++V+G  GRGK++++  L     +P  +  +  ++V  W++++    K   Y L+ WD +GQ+EF+  H+CFLS R+ YL+V+++     E+  L+P L N+K +APH+PV IVGTH D + ++ R+ + + M S I +LC  PGFP +  ++ ++    +  I  L++KI   +    I+   ++ +K P S++KLEEL     K      P++  + ++ ++    LDL++EELK AV+FLH  GV++H+ D  + L N YFL PQW+  ++ + IT+  +N FI + G +   D   LF    F K   NF   +L+ Q L++LE ++++    N+E +IP +LP + P      LS+ ++++      +I R +   ++P GFW RLIAR+ V     S  +       E   W  G+ +   + +Y ++E         E++ I+V  S++G  +L  IVD ID L+EEWY GLT+    G  ++   V C +C         L D+ S S       C +        + PD++  DL D   I+P     N S + + G GG GSV++  YK K  AVK  N V    D   ++++RQE+ I+R   HPS++S++A  V+ + I+LE AP   L  + +    L     QRIA QV  G+ +LH N IIYRD+K +N+L+F+L L     IN K++DYGISR  AP G    +GTPGY+APEV+ R   Y   AD++SFG+ L+ + T G HP +   FR                  K   +        WP MQD I+ C K VPE+RP A +I + +     ++++   P+++   +ECM T+ ++ + + +++ +G      ++  + +     K       +       +RIL +  +  S + +G  +G +W YD    + ++    LPD++LCM           + +GLA+G +        + D  +E    L   ++  P+  I         YI   S  V+    L  DT R       EID +++Q R I C           +++S    Y     E+ +  +D     LK  +D  + + E   ++      CR+  + +      L  GTG G L+I+D   +    VL   +  + C+
Sbjct:  666 ELSEVPKEIGLLSSLTSLDIGHN-SILTLPDEMGRLN--KLWELRYDRLELDLPQAILK-GRTRDLIVYLSERLRNASEHYRMKMMVVGYAGRGKSTLIRTLM-KLPQPDKSIATVGVQVKDWELRTG-RRKPPHYTLSTWDFAGQEEFYNTHQCFLSNRSLYLVVYNLQIGPSEVETLRPWLLNIKARAPHSPVIIVGTHKDGLAKDEREQKIKEMRSLISELCCKPGFPDVKAVIELNCCYESSDIERLRDKIKEAVEGFKIKGQPVMGQKIPESFIKLEELVSYEAKAR-ATLPVIKAQTLRKIIKDANLDLDNEELKQAVRFLHESGVMLHYEDASQQLENFYFLDPQWLGRMMAQVITVREINPFIDEKGILRKTDINLLFNGKRFEK--FNFPT-SLIPQYLRLLEKFEIILPRGNDEFLIPCRLPAKKPPISFPGLSDVVDSNGNRKPIQIQRQYEMPYIPLGFWSRLIARLVVFIPKMSANNPDSGVVPETVYWIEGICVYWSELLYFMIE--PFCRDGHEVVVITVPLSKMGTSVLGHIVDHIDTLIEEWYPGLTEKSPTGLELVQRIVPCSQCIGPSIHHFVLDDLVSQSELDASMNCPNCGPVPLSRLAPDVIFADLEDHFQIDPQSFFFNKSPEYLLGDGGFGSVYRAKYKNKEVAVKVFNAV---GDIHPHKMMRQEVTIIRELNHPSLISMVAVGVNPRAILLEVAPLGSLGSLLKTR-TLGRAEQQRIAMQVAEGMAYLHHNMIIYRDMKPENILIFNLALGPNVVINAKISDYGISRFAAPCGLRASEGTPGYRAPEVI-RGEVYGAQADMYSFGMTLYELVTNGRHPYDDLSFRNQLDEAVLMKRPINPITTKLDPMTGRPCCQPWPDMQDVIYLCLKYVPEERPTAAEIHEKLERCDLLSLRNFLPISKNMTVECM-TLRHDGDGMELWVGSGGSEDCAQLSWVSLTENDPKILDLTLSLQGKFHPDSRILCLTTIGSSCVLIGCLSGHIWVYDAYTREHKHKLPRLPDSVLCMHFHQNQSGDAQVYVGLASGQLAIFDANNVLTDAFAEPSYTLRFGESSEPIRCIVPHTQSKTLYIGCGSKIVM----LLPDTWRDIPQ---EIDTATEQSRGIICA----------MVVSRKYLYLAKMQEATVEAWDLNKQVLKHTIDIYKTVSEFDPSMKLSRGDCRVTSLLL-QNTHTLWVGTGEGLLVILDTNSLRPCAVLKRHRTAVRCM 1875

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Cavefish
Match: lrrk2 (leucine-rich repeat kinase 2 [Source:ZFIN;Acc:ZDB-GENE-071218-6])

HSP 1 Score: 401.364 bits (1030), Expect = 3.369e-112
Identity = 279/901 (30.97%), Postives = 478/901 (53.05%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIG-LLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLN-LLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRH--MESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKL------WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNR---IMNCYVRCLECAEQVPLLDIASI--SLRSDHFFCTSKHQNQFRI----VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKR--IVLEFAPFKDLKCVFQHY-INLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDI 5473
            K+  I P+IG L  LT LD+S N  L+S PDE+G L++  +L             KHI      ++I++Y+  RLK +V Y  ++L+V+G  G GKT+++  L++  + + K+    ++I V  W V+ +  +  +   L  WDI G +E+  +H  F+S RA YL++++++K   E+  +KP L+N+K  AP +PV +VGTH+D M E++   +C     E  +++L    GFP I +   + A   + +I+ L+  I +  +   IQ   ++ +  P  Y++LE    +    +P   P+L  + +  L+ + +L L + EL  A++FL   GV++HF+D    L +LYF+ PQW+C++I +T+ ++          + L   L+L        E+  F +E L+ Q  K+LE + +     + +++IPS L    P   L  + N+  I RI+   + P G+W R I R+  ++      F +C  E  L      WRTG+ ++ +   Y ++E     +     ++++V  S  G  +L Q+VD ID ++EEWY  L + D+HG+    +    +     A++   + +  +  S+  D     +K   Q  I    + PD++L D P   +++P +LE   SK+ + G GG GSV++  YK +  A+K  N  +H+++   +RL+RQE+ +L R  HPS+V+LLA       +V+E AP   L  +F++   + S  L  RIA QV  G+++LH + IIYRD+K  NVL+F+L+  S+I  K+ DYGI +     G    +GTPG++APEV    + Y + AD++SFG+LL+++ T G         P+EF      GK  D +  +  + W   Q+ +  C    P+DRP +  +
Sbjct: 1234 KLTEIPPQIGLLEELTSLDVSGNVGLRSFPDELGKLVRLWDLPLDGL--QLQLDLKHIGNKT--KDIVRYFQQRLKKAVPYFRMKLIVVGTAGSGKTTLIQQLMKHKRSQWKSGIGGTKISVRDWTVRDRDKKNMI---LNVWDIPGGEEYSESHPHFMSSRAMYLVLYNLSKGVSELDTVKPWLFNIKALAPLSPVILVGTHVD-MCEDHVLQECMQKLREDVLIQL----GFPAIKECPILCACEESDSISKLRKSIASGASCFKIQGQPVMGQLVPDCYVELERRVLQERTRVPPEFPVLRHQRLLQLIQESQLQLEEGELPHAIRFLSETGVLLHFDDPALQLRDLYFIDPQWLCNVISQTLILSSSGLCENTTGVVLRSVLTLCLS-----ESRCFPREHLM-QYFKLLEKFQIALPFGDEQLLIPSSLLHHKPVIKLPHSENSEMIMRIYEMPYFPMGYWSRQINRLLEVSA-----FMLCGREIPLKPTPITWRTGIYLTWDAETYCLVEAYPIEKNPSSFVKVTVPCSRKGQVLLGQVVDHIDSVLEEWYPDLLNTDIHGDGETVLKKWALYSFNDAQEQSKMQLEELLKSIDKDGLL-VNKEDPQCTIPISQICPDLILIDQPASTMLDPEELEKELSKEYLLGDGGFGSVYRAIYKNEDVAIKIFN--KHASELYVHRLVRQELTVLGRLNHPSLVALLAAGSSPHVLVMELAPCGSLDSLFENKDGSFSRKLKHRIALQVADGLRYLHSSMIIYRDLKPHNVLLFTLKTDSEIIAKITDYGIVQYCCSMGVKSSEGTPGFRAPEVARGNVIYDVQADVYSFGLLLYDLLTCGQRISDGVKFPSEFDEIAVQGKLPDPVEHYHCSPWSGFQNLMKDCLNENPQDRPTSAQV 2108

HSP 2 Score: 54.299 bits (129), Expect = 2.182e-6
Identity = 46/165 (27.88%), Postives = 78/165 (47.27%), Query Frame = 1

Query: 2380 FKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGLNISEKSLHF-LRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL 2871
             KHL  L L  N +  IP +  ++++ L  LDL +N+L  +   +     L  L++++N +            LK   +   L  +NLS N  T F        + L+ + +   G  ISE SL   L ++K + +  N +A I++ FL  C K+++ + S NKL
Sbjct:  988 LKHLLHLDLSGNKLSEIPSTLCESLQNLTRLDLQDNQLKSLTAELLSLPSLSTLSVAQNCVGPVLF-------LKPHVRCPTLRQLNLSFNCLTAFPYQLGQAMENLEDLNLE--GNQISELSLPLCLAEMKALDVSKNGVAMISDDFLSGCFKLETFSASNNKL 1143

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Cavefish
Match: lrrk1 (leucine-rich repeat kinase 1 [Source:ZFIN;Acc:ZDB-GENE-101019-2])

HSP 1 Score: 290.426 bits (742), Expect = 2.318e-78
Identity = 256/999 (25.63%), Postives = 470/999 (47.05%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNL-NIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTP------GFPKIS-KIVFVDATNFNQTITNLKNKILTV---LNDHT--IQNDHLLFEKQPSSYLKLEE--LFQEALKTLPENCPILTEKEVKDLVVKH-KLDLND-EELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLS--ENLNTSKISRIFAFSFLPTGFWPRLIARI------------------------SVLAKSFK--------HLFDICKLEFKLWRTGVIISMEDSIYLILEGKK-DTEKNLEIIEISVTKSEL-GIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECA------EQVP-------------LLDIASISLRSDHFFCTS--KHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSV-FKGYYKGKCCAVKYIN---------------VVEH--SNDAP-SYRLLRQEIDILRRFQHPSIVSLLAVDRKRI--VLEFAPFKDLKCVFQ----HYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNI-----GTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRI 5545
            ++  + P +  L +L+ L +S+NP ++ LP E+G L   NL  L  + LN+ N+P  + K+     +L +    L+ +     L+L+V+G   +GK+++L  LQ +       +    +  S W+++      +V + +  WDI G       ++CF + +A Y++++++    E +  L+  L N++ +AP++ V +VGTHLD +    R  +   + + IL LC TP      G+P I+ K +   +    + +  LK  +  V   + D T       L+    P SYL L+E  L +   +   +    LT+ E+  ++ +    D+ D E+L+ A+ FL   G ++HF DT   L  LYFL   W+   + + I +    +  +NG I   D   L     F+++TE        +Q  + L  +++    ++N  ++P  LP +   ++      +++ I R F  SF+P GFW R IAR+                        + +  SF           F + + +   W+ G++++  D  YL +E    + +K        + +S +     +  I D ++ L+E+W+  LT  +  G+ ++  Y  C  C+      + +P             + D    ++  +H  C +  K     + +VP++ + D P  + +  SDLE +  + ++ G GG+G++ ++  Y+G+  A+K                  +++H  S DA  S+   RQE  +L   QHP IV+L+ +    +   LE AP   L  V +     ++ L  +L  + AYQ+ +G+ +LH  NII+ D+K  N+LV+SLE+   +N+KL+DYGISR+    G +  +GTPGYQAPE+    I Y    D+FS+G++L+ +       +GHH  +       G +  L S      +  +Q  + +C    PE RP A  + + +  PSF  ++Y+ P  +Q+++
Sbjct:  508 QLECVPPSVCFLKNLSELYLSNNPGIQELPSELGQLS--NLWQLDIEELNISNVPADVRKDGP-AAVLAFLRAELRRAEPCKLLKLMVVGPPRQGKSALLEGLQ-TGKSTSFMSSDRSVRTSTWELERPTGVDSVCFNV--WDIGGPASMSTVNQCFFTDKALYVVIWNLALGEEAVANLQSWLLNIEARAPNSAVVVVGTHLDLIDTKFRTERIATLRAYILALCRTPSGARASGYPDITWKHLHEVSCKSLEGMDGLKRLLYQVSCSMKDITNPASCHKLVGRLIPKSYLMLQETVLAERLRRDSMDEVQYLTDLELDQIIEQSPSSDIKDYEDLQTAISFLIETGSMLHFPDTSHGLCKLYFLDAVWLSECLERIIHLKSSRSVARNGVIRAEDLRMLLVGTGFTQQTE--------EQYFQFLAKFEIALPVASNSYLLPHLLPPKPAMDIHGFRQQSSNSIQRHFKMSFVPAGFWERFIARMLISLNQMDLQAFETKRGSRSPRSRNTVIYSFAGNQQRNRCSTFRVRRSQTIYWKEGLLVTF-DGGYLSVESSDLNWKKKKSGGIKIICQSVMRDFSAMAFITDHVNALIEQWFPALTASESDGSLLIEQYAPCPHCSAVLRHSDPLPTTHANQNTVHYFNMEDCVLAAIEKEHITCPNHPKEPVALQELVPELFMTDFPSRLFLEKSDLECSEEERDILGQGGSGTIIYRAKYRGQSVAIKRFQFKKCRQQSLNSSTDTMLKHLQSMDASRSFSEFRQEASMLHTLQHPCIVALVGISIHPLCFALELAPLGSLNTVLEERSSQFLPLGHMLTFKAAYQIAAGLAYLHRKNIIFCDLKSDNILVWSLEVEDSLNIKLSDYGISRQSFHEGALGVEGTPGYQAPEI-RPGIVYDEKVDMFSYGMVLYELLSGRRPVLGHHQLQIAKKLSKGVRPVLGSPEDVQ-FHCLQALMQECWDTKPEKRPLAMPLLRQMQNPSFPCLRYLLPCQQQSQL 1489

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Cavefish
Match: stk36 (serine/threonine kinase 36 [Source:NCBI gene;Acc:103030945])

HSP 1 Score: 92.0485 bits (227), Expect = 6.896e-18
Identity = 65/196 (33.16%), Postives = 106/196 (54.08%), Query Frame = 2

Query: 4748 NMFGVGGNGSVFKGYYK--GKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLL---AVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIP--QGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGT 5314
             M G G  G V+KG  K  G+  A+K+I  V  S      R L++EI+I+R  +HP IV LL     +R+ +V+      +L  + +    L    ++ IA Q++S + +LH N I++RD+K QN+L     L     VKL D+G +R ++    V+   +GTP Y +PE++E    Y   +D++S G +L+ + T
Sbjct:    8 EMIGEGSFGRVYKGRRKFSGQVVALKFIPKVGRSEK--ELRSLKREIEIMRGLKHPHIVLLLDSFETEREVVVVTEYAEGELFQILEDDGCLPESQVRTIACQLVSALYYLHSNRILHRDMKPQNIL-----LGKGGVVKLCDFGFARSMSVSTLVLTSIKGTPLYMSPELVEE-KPYDHTSDLWSLGCILYELHT 195

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Cavefish
Match: map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:ZFIN;Acc:ZDB-GENE-081104-140])

HSP 1 Score: 85.5001 bits (210), Expect = 2.617e-17
Identity = 70/273 (25.64%), Postives = 119/273 (43.59%), Query Frame = 2

Query: 4721 DLEVNTSKDNMFGVGGNGSVFKGYY-KGKCCAVKYI--NVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRK----RIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIP--------QGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGT-------MGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDI 5473
            D  +  +K  + G G  G+V+ G   +G+  AVK +  +V         Y  L +E+D+L+  +HP+IV  L          I +E+ P   +  V   +  L   +      QV+ G+ +LH N +I+RD+K  N+++    +     VKL D+G +R L                 GTP + APEV+     +   +D++S G  +F + T       MG   A F    R G    L  + S  +   ++ C+     +  + RP+A D+
Sbjct:   11 DDTITWAKGEVLGRGAYGTVYCGLTSQGQLIAVKQVLLDVSTSETAEKEYSRLEREVDLLKNLEHPNIVGFLGTALTDNVISIFMEYVPGGSISSVLNRFGPLPEKVFALYTRQVLEGVAYLHENRVIHRDLKGNNLMLMPTGV-----VKLIDFGCARRLNRLTHSGGNSDLLKSVHGTPYWMAPEVINE-TGHGKKSDVWSIGCTVFEMATGKPPLAHMGKMAALFYIGARKGLMPPLPDDFSEEAKSFVKACL-----INQKQRPSAADL 272

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Cavefish
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:103047431])

HSP 1 Score: 85.5001 bits (210), Expect = 2.620e-17
Identity = 62/202 (30.69%), Postives = 102/202 (50.50%), Query Frame = 2

Query: 4757 GVGGNGSVFKGYYK--GKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKRIVLEFAPFKDLKCVFQHYIN-------LSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQG-------TPGYQAPEVLERCISYKLPADIFSFGILLFNIGT 5314
            G G  G V+KG +K  G+  A+K I +       PS  +  +EI +L+  QHP++V LL V  +   L +  F+ L    + Y++       +  +L++   YQ++ GI F H   +++RD+K QN+L+      +K  +KLAD+G++R      F +P         T  Y+APEVL     Y  P D++S G +   + T
Sbjct:   11 GEGTYGVVYKGRHKSTGQVVALKKIRLESEEEGVPSTAV--REISLLKELQHPNVVRLLDVLMQESKL-YLVFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLI-----DNKGVIKLADFGLAR-----AFGVPVRVYTHEVVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELAT 199

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001592.1 (pep scaffold:Pmarinus_7.0:GL477300:73535:87647:-1 gene:ENSPMAG00000001434.1 transcript:ENSPMAT00000001592.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 228.024 bits (580), Expect = 1.199e-63
Identity = 152/503 (30.22%), Postives = 256/503 (50.89%), Query Frame = 2

Query: 4460 QIVDCIDVLVEEWYAGLTD--DDLHGNRIMNCYVRCLECAE--QVPLLDIASISLRSDHFFCTSKHQNQFRI----VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVD-RKRI-VLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMG-------HHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNIL---NVFLANGNKFKQEVRS-IDIKSGQSKGKSFCKEV-DSNRILSMMVFE----SIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMGLANGTI 5890
            + VD +D L+EEW+ GL +  D    +  +      L  A+  Q P + +A++   ++     +    + RI    + PD+VL D+PD + ++ S   +  S +++ G GG GSV++  Y G   AVK  N  +H +    +RL+RQE+ +L R +HPS+VSLLAV  R R+ V+E AP   L  V +    L   L  RIA  V  G++FLH + IIYRD+K  NVL+F+L+ ++ +  K+ADYGI+R     G V P GTPGY+APEV++  + Y   AD+++FG+LL+++ T G        +P EF     +GK  D ++ +  + WP +Q+ I  C +  P+ RP A        C +   +  V          C     + SN++   ++  A+ +    E  + +++      GK   +EV    R+LS+   E      +  GT++G++W       +  ++   L + +  ++  +       ++ G ANGT+
Sbjct:    2 RAVDHVDSLIEEWFPGLLEPHDGSESSAALLHQWAGLGPADDAQPPCVRLAALQDIAESGERVAPAMPRERIPIAQLAPDVVLADVPDHLQLDLSSFSLEQSAEHLLGEGGFGSVYRALYGGDQVAVKIFN--KHISQTHPHRLMRQELAVLSRSRHPSLVSLLAVGLRPRVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGGRRIVEGLRYPHEFDELASSGKLPDPVTYYGCSPWPDVQELIAACLQPEPQHRPAASQHHSRKACSNGSLLDRV----------CNKETSSASNMVCSKHLTAAHASYPSDETTAGVELCCLDLTGKVLHREVLPDQRVLSLCSAEVNKRQWVLAGTRSGRVWVVSAAPERSRHSLHCLSEPVTALIFVAAYQNASAVLAGTANGTL 492

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001591.1 (pep scaffold:Pmarinus_7.0:GL477300:68165:86851:-1 gene:ENSPMAG00000001434.1 transcript:ENSPMAT00000001591.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 220.705 bits (561), Expect = 1.565e-60
Identity = 137/430 (31.86%), Postives = 221/430 (51.40%), Query Frame = 2

Query: 4664 VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVD-RKRI-VLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMG-------HHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSK-------GKSFCKEV-DSNRILSMMVFE----SIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMGLANGTI 5890
            + PD+VL D+PD + ++ S   +  S +++ G GG GSV++  Y G   AVK  N  +H +    +RL+RQE+ +L R +HPS+VSLLAV  R R+ V+E AP   L  V +    L   L  RIA  V  G++FLH + IIYRD+K  NVL+F+L+ ++ +  K+ADYGI+R     G V P GTPGY+APEV++  + Y   AD+++FG+LL+++ T G        +P EF     +GK  D ++ +  + WP +Q+ I  C +  P+ RP A   S+   C +   +  V          C     + SN++   +  G      V   D  +   +       GK   +EV    R+LS+   E      +  GT++G++W       +  ++   L + +  ++  +       ++ G ANGT+
Sbjct:    1 LAPDVVLADVPDHLQLDLSSFSLEQSAEHLLGEGGFGSVYRALYGGDQVAVKIFN--KHISQTHPHRLMRQELAVLSRSRHPSLVSLLAVGLRPRVLVMELAPRGSLAGVMEREGELHRTLKHRIALHVAHGLRFLHASMIIYRDLKPDNVLLFTLQPNAAVIAKIADYGIARHCCTMGMVSPDGTPGYRAPEVVKGGVMYDQQADVYAFGLLLYDLLTGGRRIVEGLRYPHEFDELASSGKLPDPVTYYGCSPWPDVQELIAACLQPEPQHRPAASQHSRKA-CSNGSLLDRV----------CNKETSSASNMVCYVVYEGLHSSHTVLPSDETTAGVELCCLDLTGKVLHREVLPDQRVLSLCSAEVNKRQWVLAGTRSGRVWVVSAAPERSRHSLHCLSEPVTALIFVAAYQNASAVLAGTANGTL 417

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004441.1 (pep scaffold:Pmarinus_7.0:GL477554:92318:114375:1 gene:ENSPMAG00000004044.1 transcript:ENSPMAT00000004441.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.561 bits (314), Expect = 8.123e-29
Identity = 141/640 (22.03%), Postives = 246/640 (38.44%), Query Frame = 2

Query: 4187 NTSKISRIFAFSFLPTGFWPRLIAR--ISVLA-------------------------------KSFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNLE--IIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECAEQV------------PLLDIASISLRSDHFFCTSKHQNQFRI--VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVK--YINVVEHSNDAPSYR---------------------------LLRQEIDILRRFQHPSIVSLLAVDR---KRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLI-----SEHSS---NSWPRMQ---DCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECM---TTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVFESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAIL 5821
             T  + R+   SF P GFW RLIAR  ISV                                 K+    F I +     W  G+ I   D  + +    K    + E   IEI V         +  + D ++ L+E W+  L D + +G   +   + C  C                 L +    ++RSD   C     N   +  ++P+  L D P  +L++ + L+ N  ++   G G +G++++  Y+G+  A+K  +I       D PS R                                         P   SL+A+ R   +R V              H + L  +L  ++ +Q+   + +LH + +++ D+K  NVLV+SL+    +N KLADYG+SR     G    +GTPGYQAPEV    + +    D+FS G++++ +   G  PA        G+ +D++      E  +    +W   Q   + + +C K  P+ RP++ ++    LC    A  Y         +EC      +   +   +  L  G+   +    + + SG  + K         +++ +    S +++ TQ+ ++  Y       E   L +PD I+
Sbjct:  503 KTMTVRRLVQMSFTPLGFWSRLIARLLISVAQIERQYVEGMENFRSRRRNVNRAVAMRLGEDKKTRASTFRIRRARKVYWHEGLAILHSDGFFSVEAAGKQWGDSGEHPGIEILVQSQSQDFSAIAFVTDHVNTLIEHWFPELMDVETNGTPFIKQLIPCPYCVGPADSREGEGQGGLFTLEECVMEAVRSDVIACHRHADNPVPLTRLIPEAFLTDFPKRLLLDVASLDYNPREELQLGQGASGTIYRALYQGQPVAIKDYHIKGAAQQEDTPSTRHPTHTPTPSPLQATHTPPHPPTPPYPLHTTPHTHPHPTSPLPRHASLVALPRGVCRRSVPGVG-------KVLHPLPLGVMLTHKVIHQMGLALAYLHRHGMLHCDLKSDNVLVWSLDPHVAVNAKLADYGVSRLSFGQGSRGSEGTPGYQAPEVRPGFV-FDERVDVFSLGMVIYEL-LSGQRPAV------EGRPLDVVRKLIRGERPTVPLEAWRHAQPLAEIMEQCWKTCPKQRPSSHEVVTS-LCDPTSAWAY--------SVECGQHNACLPCSAFPRHALLWYGDGILRRYSVLTVPSGHMQTKHL--PCPGGKVVCLTKVGSTVWIATQDLKIEIY----VLREMCPLCVPDRII 1112

HSP 2 Score: 73.1738 bits (178), Expect = 8.306e-13
Identity = 70/248 (28.23%), Postives = 115/248 (46.37%), Query Frame = 2

Query: 2864 INLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNL-NIPKHISKNAQ-LREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXX----EIEVSIWKVQSKLSE---KAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVD 3580
            ++ +   IG+L +L  L +S    ++ LP  +G L   NL  L  D L + N+P  +  +      IL Y   + + S     L+L+V+G   +GKTS+L+ L+  +  P            I +S W +Q  L     K    + + WD+ G       H C  + RA YLLV+++    E +  L   L  ++ +APHA V +VGTHLD++       +   +++ +L LC  P    +S    VD
Sbjct:   87 MDSVPSSIGSLLALQELYLSRQKGVRELPHALGSLS--NLWLLEIDELEISNVPADLLHDPNGTPAILAYLRAQQRRSQHCYSLKLMVVGPSHQGKTSLLSSLRHRRKPPPPPVSGGCPDVPIVLSTWDLQRPLGLADLKVEKIRFSVWDVGGTASALPVHRCLCTDRALYLLVWNLALGEEGVVSLHHWLLTIQARAPHAAVIVVGTHLDRLPVRFMGERLATLKAQVLSLCCDPSGRSLSGYPSVD 332

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Sea Lamprey
Match: STK36 (serine/threonine kinase 36 [Source:HGNC Symbol;Acc:HGNC:17209])

HSP 1 Score: 100.138 bits (248), Expect = 4.909e-21
Identity = 67/194 (34.54%), Postives = 108/194 (55.67%), Query Frame = 2

Query: 4748 NMFGVGGNGSVFKGY--YKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLL---AVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIP--QGTPGYQAPEVLERCISYKLPADIFSFGILLFNI 5308
             M G G  G V+KG   Y G+  A+K+I  V  S+     R LR+EIDI+R  QHP+IV +L     D++ +V+      +L  + +   NL    ++ IA Q++S + +LH + I++RD+K QN+L     L     VKL D+G +R ++    V+   +GTP Y +PE++E    Y   AD++S G +L+ +
Sbjct:    8 EMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDK--ELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNIL-----LGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEE-KPYDHTADLWSMGCILYEL 193

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Sea Lamprey
Match: stk33 (serine/threonine kinase 33 [Source:ZFIN;Acc:ZDB-GENE-040724-242])

HSP 1 Score: 87.0409 bits (214), Expect = 1.856e-18
Identity = 58/196 (29.59%), Postives = 104/196 (53.06%), Query Frame = 2

Query: 4754 FGVGGNGSVFKGYY--KGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAV----DRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKI---NVKLADYGIS--RELAPFGFVI--PQGTPGYQAPEVLERCISYKLPADIFSFGILLF 5302
             G G  G+V++  +   G   A+K +N  +    +   RLL +E+ IL+R QH +I+ L  V     R  +V+E     +L+ V +    LS    + +A+ +   I +LH ++I++RD+K++N+L  S E    I   ++++ D+G+S  RE      ++  P GTP Y A EV++    Y    D++S G++L+
Sbjct:   11 LGSGSFGTVYEATHVETGVKWAIKTVN--KERAGSSGVRLLEREVVILKRVQHQNIIHLEEVLETHKRVYLVMELCELGELRAVLEQRKRLSEAEARHVAHSLAGAIAYLHKHDIVHRDLKLENILAKSSEPHEGIDHLDIRVTDFGLSAVREGNGAASMLQSPCGTPIYMAAEVIQ-SQDYSQQCDVWSIGVILY 203

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Yeast
Match: SNF1 (AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885])

HSP 1 Score: 77.0258 bits (188), Expect = 1.948e-14
Identity = 57/190 (30.00%), Postives = 97/190 (51.05%), Query Frame = 2

Query: 4754 FGVGGNGSVFKGYYK--GKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKR----IVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQ-GTPGYQAPEVLERCISYKLPADIFSFGILLF 5302
             G G  G V   Y+   G+  A+K IN    +      R+ R EI  LR  +HP I+ L  V + +    +V+E+A  +    + Q    +S    +R   Q+IS +++ H + I++RD+K +N+L     L   +NVK+AD+G+S  +    F+    G+P Y APEV+   +      D++S G++L+
Sbjct:   61 LGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIER-EISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQR-DKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLL-----LDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILY 243

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Yeast
Match: CMK1 (Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910])

HSP 1 Score: 75.0998 bits (183), Expect = 4.548e-14
Identity = 69/269 (25.65%), Postives = 126/269 (46.84%), Query Frame = 2

Query: 4754 FGVGGNGSV--FKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLL----AVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVI--PQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLISEHSSNSWP-------------RMQDCIHKCTKLVPEDRPNAEDI--SKFILC 5491
             G G  G V   K    G+  AVK +       +      L  E+DIL+R  HP+IV+      + D+  I+ + A   +L          +     RI  +++S ++++H  NI++RD+K +N+L   ++ S +  + +AD+GI++ L     ++  P G+ GY APEVL +   +  P DI+S G++ + +   G+      + +RA +  D + E ++  +P             + +  I K   L P  RP A ++    +I+C
Sbjct:   43 LGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLY--IDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQD-GHGKPCDIWSIGVITYTL-LCGY------SAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWIIC 301

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999])

HSP 1 Score: 73.9442 bits (180), Expect = 2.219e-13
Identity = 54/193 (27.98%), Postives = 96/193 (49.74%), Query Frame = 2

Query: 4754 FGVGGNGSVFKGYYKGK--CCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKR----IVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGF--VIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNI 5308
             G G +G V+  Y  G     A+K +N+ +     P   L+  EI +++  +HP+IV+ +     +    +++E+     L  V  H I L+   +  +  + +SG++FLH   +++RDIK  N+L     LS + ++KL D+G   ++           GTP + APEV+ R   Y    DI+S GI++  +
Sbjct:  626 IGQGASGGVYTAYEIGTNVSVAIKQMNLEKQ----PKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCI-LTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNIL-----LSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRK-EYGPKVDIWSLGIMIIEM 807

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Yeast
Match: STE11 (Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354])

HSP 1 Score: 73.559 bits (179), Expect = 2.444e-13
Identity = 48/163 (29.45%), Postives = 85/163 (52.15%), Query Frame = 2

Query: 4868 LRQEIDILRRFQHPSIVSLLAVDRK----RIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFG-----FVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHP 5329
            L+ E+++L+   H +IV+     ++     I LE+ P   +  +  +Y      L+     Q++ G+ +LH  NII+RDIK  N+L+       K  VK+ D+GIS++L+P           QG+  + +PEV+++  +    ADI+S G ++  + T G HP
Sbjct:  501 LQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILI-----DIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTA-KADIWSTGCVVIEMFT-GKHP 656

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Yeast
Match: DUN1 (Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259])

HSP 1 Score: 72.7886 bits (177), Expect = 3.407e-13
Identity = 63/204 (30.88%), Postives = 101/204 (49.51%), Query Frame = 2

Query: 4784 KGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLL---------AVDRKRIVLE-------FAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVL--VFSLELSSK------------INVKLADYGISRELAPFGFVIPQ-GTPGYQAPEVLERCISYKLPADIFSFGILLF 5302
            K    G+  AVK  +  + ++D    +  R+E +IL R QHP+IV+LL         +  +K +VLE       F       C+ Q   + S  L +    Q+++G+++LH  NII+RDIK +N+L  +   E  S+            I VK+AD+G+++      F     GTP Y APEVL +   Y    D++S G++L+
Sbjct:  218 KNKKTGQQVAVKIFHA-QQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQ---DESKALFK----QLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKK-GYTSKVDLWSAGVILY 412

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Nematostella
Match: EDO37102 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGP5])

HSP 1 Score: 387.111 bits (993), Expect = 3.120e-108
Identity = 298/1076 (27.70%), Postives = 511/1076 (47.49%), Query Frame = 2

Query: 3419 KCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEEL-FQEALKTLPENCPILTEKEVKDLVVKHK--LDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLSENLNTSK-ISRIFAFSFLPTGFWPRLIARISVLAKSF-------KHLFDICKLEFKL--WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHG-----NRIMNCYVRCLECAEQVPLLDIASISLRSDHFFCTSKHQ-NQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRK--RIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAE---FRAHWRA----GKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTM-MNESNI--LNVFLANG--NKFKQEVRSIDIK-SGQSKGKSFCKEVDSNRILSMMVFES-IIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFK---VLMMGLANG--TIYYKLGYTSIQDINSEILSKLPLSDA--------PVTNIFLIDDYIFATSG--FVIYKINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYNF-DDQGIQLKPAVDCKELIKEKLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIIDQEI-NYTVVLSLFKNHIICIQHSKLHNKHDKPDKEIVSG 6490
            K  APH  + I    L  M++   K Q  +         S+ G P+I   V ++ T     I  L+N+I+ ++     +   LL  + P ++++L++L  QE       + P L   +++ L+   +  + + D EL  AV+FLH  GV+VH++D + +L++++F+KP+W+C +I   +T       + NG +  +D   LFK    S          L  Q L++LE   V+   ++ E ++PS+L  + PT    N +  +   R++  +F+P GFW RLIAR+ + A+S         H  +  ++E  L  W  GV  + ED  Y ++           I+ I V  ++LG ++L  + D +DVL+EEW+  L   D        +R+  C V   E +    L D    +   ++  C         + V PD+VL DL    +++ ++L +   K+N+ G GG G+V+K  Y G+  AVK   V   + D   +RLLRQE+  L R +HPSI++++ V  K   +VLE AP   L  +      LS  L  RIA QV  G+ +LH + I+YRD+K  N+L+FSL L   IN K++DYGI+R    +G   P+GTPGY+APEV    ++Y   AD++SFG+ L+ + T G  P E   FR+   A    G+ ++ I++     WP + D I    +  P+ RP A+++ + +     V +K    + +   +ECM      E N   + V+  +G  + +  +V   DI  +G  +G      V   RI+ +    S ++  GTQ+G LW +D   +K  ++   LPDA+LC  ++ + D      V++ GLA+G   +Y  +       +   I      SDA        PV  I      ++   G   ++ + N     ER  +V+       D++R +          N   + +  +T   +S   +F D   +     +DC+ ++ E   +N  S+  R++CM +      L  G G G++I++     +   V++     + C+  +   +   +P   ++SG
Sbjct: 1329 KASAPHNELIIRDWVLQSMRD---KAQSLY--------SSSAGLPEIKAHVVLNCTAETPGIQALRNRIVNLIVKCKCKGHSLLGSRVPQAFVRLQQLVLQETASG--NSAPFLYRGDLRRLLQDQEDEVSMCDSELGQAVKFLHEAGVLVHYDDPVAHLSDVFFVKPEWLCHVISSVVTTGNDKGLVTNGILKRDDLHFLFKPEVGSHAE-------LTPQLLRLLERSGVLLPVNSTEFLMPSRLSRKEPTITLPNPSPERSCRRLYDLAFVPPGFWARLIARLLLFARSMISVDLNVTHEDEPHQVEPALHYWCDGVYATWEDHAYFLVNQDSSETYGTNILSILVPNTKLGFRLLGNLTDHVDVLIEEWFPSLNGVDPVQCLPLVSRLCPCLVCEGEYSHAFALEDCTEYACTHEYVTCPKTSVIMPLQHVAPDVVLADLDQQWMLDSAELCLEEKKENVLGDGGYGTVYKAKYYGQFVAVK---VFRKATDVCPHRLLRQEVPFLSRLRHPSIINMIGVALKPRALVLELAPLGSLSSLLSKGEGLSRGLQHRIALQVAEGLAYLHKHMIVYRDLKPHNILIFSLSLGILINAKISDYGIARYATLYGLTAPEGTPGYRAPEVARGDVAYNKEADMYSFGMFLYELVTGGKRPFEDLRFRSELDAAVVQGRMVEPITDSGCPPWPDVSDMIEHLLEPRPDLRPTAQEVFERLYTAELVCLKRDVVVCKGQTVECMAVRHYTEGNTDRMEVWTGSGLSDNYTGQVSWFDIADTGGCRGTL----VSDKRIMCITAVHSHLVVAGTQSGTLWIFDAWTHKCLHSLPALPDAVLC--LRHFFDIKTGQDVVVAGLADGKLAVYQTISLQKQDAVPHMITFCRTGSDATCQDCASHPVACITQARKRLYVGCGNDVIVVQPNDGFAVERRWSVQ-------DRNRGL---------VNNIAVGAQIWTSTKDSPSVDFWDVSKVVHHGTIDCRSIL-EASGVNEDSHEMRVVCMLLHR-RTALWVGLGGGHVIVLSPTTCDPLCVINRHVGAVRCLALAARRSIAGRPVSFVLSG 2357

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Nematostella
Match: EDO31971 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWE1])

HSP 1 Score: 216.083 bits (549), Expect = 6.697e-59
Identity = 151/492 (30.69%), Postives = 263/492 (53.46%), Query Frame = 2

Query: 2870 LISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLN-IPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQ---SKLSEKAVD------YKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPE--NCPILTEKEVKDLVVKHKL-DLND-EELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAP-----------TNLSENLNTSKISRIFAFSFLPTGFWPRLIARISV 4270
            ++ P +  L++L  LD+S+NP+L++LP ++G L+  +   L  + L L  +PKH+      ++ L +    L+ SV Y  ++L+V+G++G GKT++L  L+G  L    +     I V  W VQ   S LS   +         L+ WD++GQ  ++  H+ FL+    YL V++ T   E +  L+  L N+K +AP++ V I+GTHLD++   +R+++ + +   I+K   T GFPKI     V A    + IT LK  I     +   Q   ++ ++ P SY++L++  +       E    PIL E+E+  L   +K  D++D EEL LA +FLH+ GV++H+ND +  LN LYF+ P W+C +I   +T+   N ++++G +  ++   + +D  F     NF     + Q L+++E +++     + +I+IPS LP +AP              S + +   I R +  +++P+G W RLI R+ V
Sbjct:  167 VVPPSVCRLTNLNELDLSNNPDLRTLPPQLGNLR--DCWQLRLNKLTLTELPKHVRPGVLSKDTLAFLRATLRKSVPYYRMKLMVVGIQGYGKTTLLAALKGQPLPSNLSTVG--IVVDEWSVQISTSLLSRIGITSGIGPTITLSTWDLAGQSVYYAAHQMFLTPSTLYLAVWNATLGEEGVENLRSWLLNIKARAPYSDVIIIGTHLDRIPRASRESRVKELNHMIMKRYDTKGFPKIVGYTVVSAVT-GEGITELKELIYKKAINSKEQGQLVIGKQVPLSYIQLQDAIRHEADRRREARKPPILLEEEMLALAAGNKDNDIHDHEELALATRFLHDNGVLLHYNDQLRGLNTLYFIDPAWVCDLIASIVTVREKNGYVRDGIMLTSNVRMVLRDPRFPP---NF-----IPQYLQLMERFEIALTLDDFQILIPSMLPHEAPGMKMNELYRLFQRTSPDNSHDSIQRNYQMAYVPSGLWSRLITRLLV 645

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Nematostella
Match: EDO31970 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWE0])

HSP 1 Score: 105.145 bits (261), Expect = 2.272e-25
Identity = 69/187 (36.90%), Postives = 99/187 (52.94%), Query Frame = 2

Query: 4664 VVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKRI--VLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTP 5218
            +VPD+++ DLP  +L+   D        +  G GG G VF+G  +    AVK      HS  A   RL++  + +L   QHP +V LL V  + +  +LE AP   L  V +  I L     ++    V S + +LH ++IIYRD+K  NVLV+SL  +  +NVKL+DYGIS    P G    +GTP
Sbjct:   20 LVPDLMMTDLPRHLLVERCDFSYRDDAASRLGGGGAGEVFRGELRNSFVAVKTF----HSTRA--LRLVQIRVAVLCHLQHPCVVRLLGVCLRPLCFLLELAPHGSLASVMED-ITLGRRETEK--EHVASALWYLHDSDIIYRDLKTDNVLVWSLHDTDLVNVKLSDYGISCFATPQGVAGDEGTP 197

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Nematostella
Match: EDO31590 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXH7])

HSP 1 Score: 105.531 bits (262), Expect = 5.595e-25
Identity = 66/191 (34.55%), Postives = 106/191 (55.50%), Query Frame = 2

Query: 4757 GVGGNGSVFKGYYKGKCCAVKYINVVEHSNDA-PSYRLLRQEIDILRRF-QHPSIVSLLAVDRKRI--VLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLE-RCISYKLPADIFSFGILLFNIGT 5314
            G GG G V +G  +G+  A+K+ +  +   D    Y   R+E+++LRR  QHP +++++ V  + +  VLE A   +L       I +  ++L RIAYQ+   + +LH   +IYRD+K +N+LV+SL     + VKL D+G +      G +  +GT G  APE+L+     Y    DI+S+ ILL+ I T
Sbjct:    2 GSGGFGKVVRGECRGQPVAIKFFDKCDDEIDPLRHYFEARKELNVLRRVRQHPYLINIIGVSLRPLCLVLELAEKGNLSESLSSPIPIHRIVLFRIAYQIADALAYLHTLGVIYRDLKPENILVWSLNEGDDLYVKLIDFGTANFATSAGLISMKGTSGNHAPEMLDVEKREYTEQVDIYSYAILLYQIIT 192

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Nematostella
Match: EDO27465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T966])

HSP 1 Score: 104.76 bits (260), Expect = 4.325e-24
Identity = 54/168 (32.14%), Postives = 93/168 (55.36%), Query Frame = 2

Query: 3812 EELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAP-----------------TNLSENLNTSKISRIFAFSFLPTGFWPRLIARI 4264
            +EL+ A +FLH+ GV++H++D +  L +LYFL PQW+C ++   +T+  +N  I NG + L+D   +F+       +ENF    L+KQ + +L  ++V    S+  +++PS LP + P                  N++    T  + R +  S++P+GFWPRLI R+
Sbjct:   18 DELQQATKFLHDNGVLLHYDDPL--LRDLYFLDPQWLCDMLAHVVTIREVNPHINNGVMKLSDLSHIFR-------SENFPA-NLIKQYINLLSKFEVALPWSSEYLLVPSLLPDRQPISNQPIAPGGNPVVTRAMNMTAYTKTRVLRRQYIMSYIPSGFWPRLITRV 175

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Medaka
Match: lrrk2 (leucine rich repeat kinase 2 [Source:NCBI gene;Acc:101155093])

HSP 1 Score: 411.379 bits (1056), Expect = 1.804e-115
Identity = 345/1220 (28.28%), Postives = 590/1220 (48.36%), Query Frame = 2

Query: 2861 KINLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEE-LFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPT-NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKL------WRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNR---IMNCYVRCLECAEQVPLLDIASISLRSDHFFCTSKHQNQ-----FRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDR--KRIVLEFAPFKDLKCVFQHY-INLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHH-------PAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQS--KGKSFCKEVDSNRILSMMVF----ESIIFL--GTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMGLANG--TIY----------YKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDYIFATSGFVIYKINLSIDTE--RFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKEKLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIID 6376
            K++ +  +IG L  LT LD+SHN  L+S PDE+G  K   L  L  DGL L +   +  N + ++I++    RLK +V Y+ ++L+V+G    GKT++++ L   K +  +N  ++ I V  W ++ +  +K V   L  WD +G +EF  +H  FL+ RA YL+V++++K + ++  LKP L+ +K  AP +PV +VGTH D   E + +   +   + +L   +  GFP I           + +I NL+  I   +    IQ   ++ +  P SY++LE  +  E  +  PE  P+L   ++  L+ + +L L + EL  AV FL   G+++HFND    L  LYF+ PQW+C+I+ + +T+       Q   I     +    + F S E++ F K  LV Q +K+LE + +      +++++PS L    P   L    N+  I R +   + P  +W R I R+  ++      + +C  +  L      WR GV ++     Y ++E   +       ++I+V  S  G  +L Q+VD  D ++EEW+ GL + D+HGN    I    V      +Q   + +  +   SD+ F     ++        ++ PD+VL D P   +++  +LEV+ SK++  G GG G+V++G YK +  AVK  N  +H+++   YRLLRQE+ +L R +HPS+V LLA     + +V+E A    L  +F+H   +LS  L  RI+ QV  G+++LH   IIYRD+K  NVL+F+L+  S+I VK+ DYGI++     G    +GTPG++APEV      Y   AD+FS G+LL+++ T G         P+EF      G   D +  +  + WP  Q  +  C K  P+DRP +  +   +     + +       R  R EC+T             ++G+    E        G S  + + F  EVDS+ +LS++      E+  +L  GTQ+G L      +    +    + DA+  +   +   Y   L++G A+G  ++Y            +   ++ ++N+ ++   P   +  +            S  V Y ++ SIDT    + AV L  +       ++ C      + N       Y +    S +  +D +  +L   +DC  +I+         Y+  +  + + S +  L  GT  G+L++++
Sbjct: 1010 KLSEVPAQIGLLDGLTSLDVSHNSGLRSFPDEMG--KLSKLWDLPLDGLRLQLDFKLIGN-KTKDIIRSLQQRLKKAVPYHRMKLIVVGNPSSGKTTLIHQLMKQKRQLNSNQNAAGINVLDWTIKDRDKKKMV---LNVWDFTGGEEFSGSHLHFLTSRAVYLVVYNLSKGSSQVDALKPWLFTIKAVAPLSPVILVGTHADVSDELHFQDCLKKTRAELL---NHQGFPAIRDHHMGYFCEDSDSIANLRKAITREVTSFKIQGQLVMGQLVPDSYVELERRVLLERTRISPE-FPVLRRYQLLQLIQECQLQLEEAELPHAVHFLSEVGILLHFNDPGLRLQELYFIDPQWLCNILSQKLTLKSCGLREQPKGIVQRSVM----EKFLS-ESKCFPKSHLV-QFVKLLEKFQIALPLGEDQLLVPSSLSKHRPVIELPHCENSEVIVRFYEMPYFPMDYWSRQICRLLEVSS-----YLLCGQDKMLRPNRIYWRRGVYLNWCPEAYCLVEAASEEGSPSSFVKITVPMSRKGRVLLGQVVDHTDSVLEEWFPGLLNTDMHGNGEALIKRWAVYSFHDGQQPSKILLEDLFRYSDNDFLLVNPEDPGCTVPISLIAPDLVLSDQPAGTMLDREELEVDLSKESRLGDGGFGTVYRGVYKNEDVAVKIFN--KHASELYVYRLLRQELAVLGRLRHPSLVGLLAAGSAPQVLVMELALRGSLDALFEHQNGSLSRKLQHRISLQVADGLRYLHSAMIIYRDLKPHNVLLFNLKTDSEIIVKITDYGIAQYCCSMGVRSSEGTPGFRAPEVARGNAVYNQQADVFSLGLLLYDLLTCGERISDGMKFPSEFDEVAVQGNLPDPVQHYGCSPWPGFQALMKDCLKENPQDRPTSAQVFDRLNSGGMLCLMMEVRDPRLLRAECITA------------SSGSGEGPESSHTAWLGGGSSTQRRGFVTEVDSSPVLSLVTVRIPNEACHWLVAGTQSGSLLVISTEDLSSWHYLQGVTDAVTSLYFHAQKSY---LLVGTADGILSVYEDSVLPQTNGRPVKTLTVGNVNTPLMCLGPSLHSADSRTLWAGCGTNILSFSVDYDVSRSIDTRPNAYFAVFLHSL-------VLACVSRMVVDKN------VYLSKAGASTVEVWDKRSERLMECIDCCHIIR---------YTHTLKALLLQS-NAALWIGTRGGHLLLLE 2168

HSP 2 Score: 53.5286 bits (127), Expect = 3.668e-6
Identity = 51/175 (29.14%), Postives = 81/175 (46.29%), Query Frame = 1

Query: 2362 LASDSLFKH----LTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGLNISEKSLHF-LRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL 2871
            LA DS  +     L  L L  N++   P +  QN+  L  LDL  N+L  +P  +     L  LN+S+N I    LS     T  + +       +NLS NK + F        Q+L+ + +   G  I+E  +   L ++K + +  NS+ +I   FL NC K++ +N S + L
Sbjct:  752 LAEDSFVQQQLGFLLRLDLCHNNLTEFPSTICQNLRSLTRLDLQGNQLKSLPEGLLALPSLSTLNVSRNCIGP-TLSFDPAVTCPALKH------LNLSFNKISTFPHQLGCSMQKLEELFLE--GNCITELCVPLCLPEIKLLDVSRNSVDNICPDFLSNCCKLEHLNSSASFL 917

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Medaka
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:100049478])

HSP 1 Score: 82.8037 bits (203), Expect = 2.422e-16
Identity = 62/202 (30.69%), Postives = 101/202 (50.00%), Query Frame = 2

Query: 4757 GVGGNGSVFKGYYK--GKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAV----DRKRIVLEFAPFKDLKCVFQHYIN---LSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQG-------TPGYQAPEVLERCISYKLPADIFSFGILLFNIGT 5314
            G G  G V+KG +K  G+  A+K I +       PS  +  +E+ +L+  +HP++V LL V     R  ++ EF    DLK       +   +  +L++   YQ++ GI F H   +++RD+K QN+L+      +K  +KLAD+G++R      F +P         T  Y+APEVL     Y  P D++S G +   + T
Sbjct:   11 GEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAV--REVSLLQELKHPNVVRLLDVLMQESRLYLIFEFLSM-DLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLI-----DNKGVIKLADFGLAR-----AFGVPVRVYTHEVVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELAT 199

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Medaka
Match: cdk6 (cyclin dependent kinase 6 [Source:NCBI gene;Acc:101168879])

HSP 1 Score: 78.5666 bits (192), Expect = 8.942e-15
Identity = 70/249 (28.11%), Postives = 117/249 (46.99%), Query Frame = 2

Query: 4757 GVGGNGSVFKGY---YKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRR---FQHPSIVSLLAV------DRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIA-------------YQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISR----ELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHW---RAGKQIDLISEHSSNSWPR 5407
            G G  G V+K      +G+  A+K + V       P   +  +E+ +LR+   F+HP++V L  V      DR+           L  VF+H     +  L+++              YQ++ G+ FLH + +++RD+K QN+LV     +S   +KLAD+G++R    ++A    V+   T  Y+APEVL +  SY  P D++S G +      M      FR +    + GK  D++   S+  WP+
Sbjct:   17 GEGAYGKVYKARDLKNEGRFVALKRVRVQTEEEGMPLSTI--REVAVLRQLEAFEHPNVVRLFDVCTVSRTDRE---------TKLTLVFEHVDQDLTTYLEKVPDPGVPPETIKDMMYQLLQGLDFLHSHRVVHRDLKPQNILV-----TSGGQIKLADFGLARIYSFQMALTSVVV---TLWYRAPEVLLQS-SYATPVDLWSVGCIF---AEMFRRRPLFRGNSDVDQLGKIFDVVGVPSAEDWPQ 242

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Medaka
Match: si:ch211-22d5.2 (serine/threonine-protein kinase NIM1-like [Source:NCBI gene;Acc:101156106])

HSP 1 Score: 80.1073 bits (196), Expect = 9.454e-15
Identity = 79/274 (28.83%), Postives = 124/274 (45.26%), Query Frame = 2

Query: 4847 DAPSYRLLRQEIDILRRFQHPSIVSLLAV----DRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQ--GTPGYQAPEVLERCISYKLPADIFSFGILLFNI--GTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRM----QDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRS 5632
            DA + RLL +EI+ +   QHP+IV L  V     R  +VLE+A   DL         L     +    QV+S I+++H  +II+RD+K +NVL      +S   VK+AD+G S  ++     +    G+P Y APE+         P D+++ G+LLF +  GTM      FRA    GK    I E +    P +    Q  I    K  P +R     I + + C   + +++ W L        +  +++     +V      +  +EVRS
Sbjct:  105 DAQAQRLLSREINSMEALQHPNIVRLYEVVETPSRLYLVLEYAGGGDLHNRICSEGKLCDNTSKVTFAQVLSAIKYMHNLSIIHRDLKAENVL-----FTSSGAVKVADFGFSTRVSNRNLALDTFCGSPPYAAPELFRDESYLGPPVDVWAMGVLLFFMVTGTM-----PFRAE-TMGKLRRCIIEGNYTLPPWVPGPCQRLIRGILKPAPAER---YAIDQMLGCDWLLPVEFPWSLVPPEPTNALQRLLDSERSSSV----EAELHEEVRS 360

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Query: 4847 DAPSYRLLRQEIDILRRFQHPSIVSLLAV----DRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQ--GTPGYQAPEVLERCISYKLPADIFSFGILLFNI--GTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRM----QDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRS 5632
            DA + RLL +EI+ +   QHP+IV L  V     R  +VLE+A   DL         L     +    QV+S I+++H  +II+RD+K +NVL      +S   VK+AD+G S  ++     +    G+P Y APE+         P D+++ G+LLF +  GTM      FRA    GK    I E +    P +    Q  I    K  P +R     I + + C   + +++ W L        +  +++     +V      +  +EVRS
Sbjct:  105 DAQAQRLLSREINSMEALQHPNIVRLYEVVETPSRLYLVLEYAGGGDLHNRICSEGKLCDNTSKVTFAQVLSAIKYMHNLSIIHRDLKAENVL-----FTSSGAVKVADFGFSTRVSNRNLALDTFCGSPPYAAPELFRDESYLGPPVDVWAMGVLLFFMVTGTM-----PFRAE-TMGKLRRCIIEGNYTLPPWVPGPCQRLIRGILKPAPAER---YAIDQMLGCDWLLPVEFPWSLVPPEPTNALQRLLDSERSSSV----EAELHEEVRS 360

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BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Planmine SMEST
Match: SMESG000056130.1 (SMESG000056130.1)

HSP 1 Score: 2543.07 bits (6590), Expect = 0.000e+0
Identity = 1270/1278 (99.37%), Postives = 1273/1278 (99.61%), Query Frame = 2

Query: 2873 ISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECAEQVPLLDIASISLRSDHFFCTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVFESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDYIFATSGFVIYKINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKEKLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIIDQEINYTVVLSLFKNHIICIQHSKLHNKHDKPDKEIVSGPTPEKPDVTDHLINCTETFESSAENTGLIIVGNGYKSIEEDFDGAVLIVLSDDISNISRQLEEHINSRNHIL 6706
            IS EIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNGLRLVVLGLKGRGKTSVLNLLQGSKLKPKNNNKSSEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRL+TFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECAEQ+PLLDIASISLRSDHFFCTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVFESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLM+GLANGTIYYKLGYTSIQDINSEILSKL LSDAPVTNIFLIDDYIFATSGFVIYKINLSIDTERF AVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKEKLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIIDQEINYTVVLSLFKNHIICIQHSKL NKHDKPDKEIVSGPTPEKPDVTDHLIN TETFESSAENTGLIIVGNGYKSIEEDFDGAVLIVLSDDISNISRQLEEHINSRNHIL
Sbjct: 1333 ISSEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNGLRLVVLGLKGRGKTSVLNLLQGSKLKPKNNNKSSEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLDTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECAEQIPLLDIASISLRSDHFFCTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVFESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMVGLANGTIYYKLGYTSIQDINSEILSKLQLSDAPVTNIFLIDDYIFATSGFVIYKINLSIDTERFMAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKEKLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIIDQEINYTVVLSLFKNHIICIQHSKLLNKHDKPDKEIVSGPTPEKPDVTDHLINFTETFESSAENTGLIIVGNGYKSIEEDFDGAVLIVLSDDISNISRQLEEHINSRNHIL 2610

HSP 2 Score: 1831.61 bits (4743), Expect = 0.000e+0
Identity = 951/957 (99.37%), Postives = 954/957 (99.69%), Query Frame = 1

Query:    1 HIYHSDIGTFVLENLKKYNMKEILIYGFKMLYLFVSLSKSLKRLLNESDQESWIQFILDVLKNNLQCSETINWSFSVINRIIVLDPNLVRLIENKEFXXXXXXXXXXXXIFYSQTELSISTLCSCFEITSILSKYSEKIQNHFLESQIQTLIHLMVVRCLQTKSLSKEIECQIRLAATNAMKSLILYNLPAKELFYNEQTQYEDAKRFLVSCCQHNHDDCKYEEXXXXXXXXXXXXVEYNSIKYDLMQTLQSTLMKLLSCERCSMSPTIIEAFQELLIVLSGFEHETLFILDILSIRECCELASKFLNFYAIQKNTVIFIQLNSSSINKVEKLKILQIIGETIFRATSLFKNCLIIRAEACVLIQILLKQYPEFSPICVENNLDKFLFETINMNQNPDLIKIGLQAFYVLTELQENRDLILIKAIKESKLKLVQCLIAIGSDLAKVSKDALLSAVKQKDEAISFQLMSHLVNNGCKPEFYLITCCFDTNNYKNAIVLLRHYGINDSTEGKIINWSDLGMRHFHISWLEDLCEKQKLQIDPNVIWLSKRIKQESKNRMLLRQNYEKYQNSHVKSYRYPETQMRTLDKDIAGHKNYTRINNGIPIRISNIGKQNLFYNSSLHENSHNLINYPGNYSLRYPEKLQQNIVKEDAKSEEFCVTSKTIIKQKSNMRGYLPVKGEISEFLTAFRCGTDFSYHPLDPRCLQEKQNKNLDYLSERESGVVFDFHESPLQFSIKSPKDYKNDENTSISSALLETSIENQIQRNKVGYXXXXXXXXXXXEDFIEFKMQLASDSLFKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGLNISEKSLHFLRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL 2871
            H YHSDI TF+LENLKKYNMKEILI GFK+LYLFVSLSKSLKRLLNESDQESWIQFILDVLKNNLQCSETINWSFSVINRIIVLDPNLVRLIENKEFLQDTSLDTLLLQIFYSQTELSISTLCSCFEITSILSKYSEKIQNHFLESQIQTLIHLMVVRCLQTKSLSKEIECQIRLAATNAMKSLILYNLPAKELFYNEQTQYEDAKRFLVSCCQHNHDDCKYEECLAATLLFLACLVEYNSIKYDLMQTLQSTLMKLLSCERCSMSPTIIEAFQELLIVLSGFEHETLFILDILSIRECCELASKFLNFYAIQKNTVIFIQLNSSSINKVEKLKILQIIGETIFRATSLFKNCLIIRAEACVLIQILLKQYPEFSPICVENNLDKFLFETINMNQNPDLIKIGLQAFYVLTELQENRDLILIKAIKESKLKLVQCLIAIGSDLAKVSKDALLSAVKQKDEAISFQLMSHLVNNGCKPEFYLITCCFDTNNYKNAIVLLRHYGINDSTEGKIINWSDLGMRHFHISWLEDLCEKQKLQIDPNVIWLSKRIKQESKNRMLLRQNYEKYQNSHVKSYRYPETQMRTLDKDIAGHKNYTRINNGIPIRISNIGKQNLFYNSSLHENSHNLINYPGNYSLRYPEKLQQNIVKEDAKSEEFCVTSKTIIKQKSNMRGYLPVKGEISEFLTAFRCGTDFSYHPLDPRCLQEKQNKNLDYLSERESGVVFDFHESPLQFSIKSPKDYKNDENTSISSALLETSIENQIQRNKVGYLNLSKNKLSNLEDFIEFKMQLASDSLFKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIG+NISEKSLHFLRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL
Sbjct:  270 HRYHSDIVTFLLENLKKYNMKEILICGFKILYLFVSLSKSLKRLLNESDQESWIQFILDVLKNNLQCSETINWSFSVINRIIVLDPNLVRLIENKEFLQDTSLDTLLLQIFYSQTELSISTLCSCFEITSILSKYSEKIQNHFLESQIQTLIHLMVVRCLQTKSLSKEIECQIRLAATNAMKSLILYNLPAKELFYNEQTQYEDAKRFLVSCCQHNHDDCKYEECLAATLLFLACLVEYNSIKYDLMQTLQSTLMKLLSCERCSMSPTIIEAFQELLIVLSGFEHETLFILDILSIRECCELASKFLNFYAIQKNTVIFIQLNSSSINKVEKLKILQIIGETIFRATSLFKNCLIIRAEACVLIQILLKQYPEFSPICVENNLDKFLFETINMNQNPDLIKIGLQAFYVLTELQENRDLILIKAIKESKLKLVQCLIAIGSDLAKVSKDALLSAVKQKDEAISFQLMSHLVNNGCKPEFYLITCCFDTNNYKNAIVLLRHYGINDSTEGKIINWSDLGMRHFHISWLEDLCEKQKLQIDPNVIWLSKRIKQESKNRMLLRQNYEKYQNSHVKSYRYPETQMRTLDKDIAGHKNYTRINNGIPIRISNIGKQNLFYNSSLHENSHNLINYPGNYSLRYPEKLQQNIVKEDAKSEEFCVTSKTIIKQKSNMRGYLPVKGEISEFLTAFRCGTDFSYHPLDPRCLQEKQNKNLDYLSERESGVVFDFHESPLQFSIKSPKDYKNDENTSISSALLETSIENQIQRNKVGYLNLSKNKLSNLEDFIEFKMQLASDSLFKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGVNISEKSLHFLRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL 1226

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Planmine SMEST
Match: SMESG000056130.1 (SMESG000056130.1)

HSP 1 Score: 2491.84 bits (6457), Expect = 0.000e+0
Identity = 1251/1278 (97.89%), Postives = 1255/1278 (98.20%), Query Frame = 2

Query: 2873 ISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECAEQVPLLDIASISLRSDHFFCTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVFESIIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMGLANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDYIFATSGFVIYKINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKEKLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIIDQEINYTVVLSLFKNHIICIQHSKLHNKHDKPDKEIVSGPTPEKPDVTDHLINCTETFESSAENTGLIIVGNGYKSIEEDFDGAVLIVLSDDISNISRQLEEHINSRNHIL 6706
            IS EIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNGLRLVVLGLKGRGKTSVLNLLQGSKLKPKNNNKSSEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRL+TFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECAEQ+PLLDIASISLRSDHFFCTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVFE                  +NKFENTNLVLPDAILCMVMKSYVDYFKVLM+GLANGTIYYKLGYTSIQDINSEILSKL LSDAPVTNIFLIDDYIFATSGFVIYKINLSIDTERF AVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKEKLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIIDQEINYTVVLSLFKNHIICIQHSKL NKHDKPDKEIVSGPTPEKPDVTDHLIN TETFESSAENTGLIIVGNGYKSIEEDFDGAVLIVLSDDISNISRQLEEHINSRNHIL
Sbjct: 1333 ISSEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVRDGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNGLRLVVLGLKGRGKTSVLNLLQGSKLKPKNNNKSSEIEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLDTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECAEQIPLLDIASISLRSDHFFCTSKHQNQFRIVVPDIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKYINVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKRIVLEFAPFKDLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFSLELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPADIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCIHKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNESNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVFE------------------KNKFENTNLVLPDAILCMVMKSYVDYFKVLMVGLANGTIYYKLGYTSIQDINSEILSKLQLSDAPVTNIFLIDDYIFATSGFVIYKINLSIDTERFMAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYFTIRNESLIYNFDDQGIQLKPAVDCKELIKEKLNINSKSYSCRIMCMTIWSGDRYLCAGTGNGYLIIIDQEINYTVVLSLFKNHIICIQHSKLLNKHDKPDKEIVSGPTPEKPDVTDHLINFTETFESSAENTGLIIVGNGYKSIEEDFDGAVLIVLSDDISNISRQLEEHINSRNHIL 2592

HSP 2 Score: 1831.61 bits (4743), Expect = 0.000e+0
Identity = 951/957 (99.37%), Postives = 954/957 (99.69%), Query Frame = 1

Query:    1 HIYHSDIGTFVLENLKKYNMKEILIYGFKMLYLFVSLSKSLKRLLNESDQESWIQFILDVLKNNLQCSETINWSFSVINRIIVLDPNLVRLIENKEFXXXXXXXXXXXXIFYSQTELSISTLCSCFEITSILSKYSEKIQNHFLESQIQTLIHLMVVRCLQTKSLSKEIECQIRLAATNAMKSLILYNLPAKELFYNEQTQYEDAKRFLVSCCQHNHDDCKYEEXXXXXXXXXXXXVEYNSIKYDLMQTLQSTLMKLLSCERCSMSPTIIEAFQELLIVLSGFEHETLFILDILSIRECCELASKFLNFYAIQKNTVIFIQLNSSSINKVEKLKILQIIGETIFRATSLFKNCLIIRAEACVLIQILLKQYPEFSPICVENNLDKFLFETINMNQNPDLIKIGLQAFYVLTELQENRDLILIKAIKESKLKLVQCLIAIGSDLAKVSKDALLSAVKQKDEAISFQLMSHLVNNGCKPEFYLITCCFDTNNYKNAIVLLRHYGINDSTEGKIINWSDLGMRHFHISWLEDLCEKQKLQIDPNVIWLSKRIKQESKNRMLLRQNYEKYQNSHVKSYRYPETQMRTLDKDIAGHKNYTRINNGIPIRISNIGKQNLFYNSSLHENSHNLINYPGNYSLRYPEKLQQNIVKEDAKSEEFCVTSKTIIKQKSNMRGYLPVKGEISEFLTAFRCGTDFSYHPLDPRCLQEKQNKNLDYLSERESGVVFDFHESPLQFSIKSPKDYKNDENTSISSALLETSIENQIQRNKVGYXXXXXXXXXXXEDFIEFKMQLASDSLFKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGLNISEKSLHFLRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL 2871
            H YHSDI TF+LENLKKYNMKEILI GFK+LYLFVSLSKSLKRLLNESDQESWIQFILDVLKNNLQCSETINWSFSVINRIIVLDPNLVRLIENKEFLQDTSLDTLLLQIFYSQTELSISTLCSCFEITSILSKYSEKIQNHFLESQIQTLIHLMVVRCLQTKSLSKEIECQIRLAATNAMKSLILYNLPAKELFYNEQTQYEDAKRFLVSCCQHNHDDCKYEECLAATLLFLACLVEYNSIKYDLMQTLQSTLMKLLSCERCSMSPTIIEAFQELLIVLSGFEHETLFILDILSIRECCELASKFLNFYAIQKNTVIFIQLNSSSINKVEKLKILQIIGETIFRATSLFKNCLIIRAEACVLIQILLKQYPEFSPICVENNLDKFLFETINMNQNPDLIKIGLQAFYVLTELQENRDLILIKAIKESKLKLVQCLIAIGSDLAKVSKDALLSAVKQKDEAISFQLMSHLVNNGCKPEFYLITCCFDTNNYKNAIVLLRHYGINDSTEGKIINWSDLGMRHFHISWLEDLCEKQKLQIDPNVIWLSKRIKQESKNRMLLRQNYEKYQNSHVKSYRYPETQMRTLDKDIAGHKNYTRINNGIPIRISNIGKQNLFYNSSLHENSHNLINYPGNYSLRYPEKLQQNIVKEDAKSEEFCVTSKTIIKQKSNMRGYLPVKGEISEFLTAFRCGTDFSYHPLDPRCLQEKQNKNLDYLSERESGVVFDFHESPLQFSIKSPKDYKNDENTSISSALLETSIENQIQRNKVGYLNLSKNKLSNLEDFIEFKMQLASDSLFKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIG+NISEKSLHFLRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL
Sbjct:  270 HRYHSDIVTFLLENLKKYNMKEILICGFKILYLFVSLSKSLKRLLNESDQESWIQFILDVLKNNLQCSETINWSFSVINRIIVLDPNLVRLIENKEFLQDTSLDTLLLQIFYSQTELSISTLCSCFEITSILSKYSEKIQNHFLESQIQTLIHLMVVRCLQTKSLSKEIECQIRLAATNAMKSLILYNLPAKELFYNEQTQYEDAKRFLVSCCQHNHDDCKYEECLAATLLFLACLVEYNSIKYDLMQTLQSTLMKLLSCERCSMSPTIIEAFQELLIVLSGFEHETLFILDILSIRECCELASKFLNFYAIQKNTVIFIQLNSSSINKVEKLKILQIIGETIFRATSLFKNCLIIRAEACVLIQILLKQYPEFSPICVENNLDKFLFETINMNQNPDLIKIGLQAFYVLTELQENRDLILIKAIKESKLKLVQCLIAIGSDLAKVSKDALLSAVKQKDEAISFQLMSHLVNNGCKPEFYLITCCFDTNNYKNAIVLLRHYGINDSTEGKIINWSDLGMRHFHISWLEDLCEKQKLQIDPNVIWLSKRIKQESKNRMLLRQNYEKYQNSHVKSYRYPETQMRTLDKDIAGHKNYTRINNGIPIRISNIGKQNLFYNSSLHENSHNLINYPGNYSLRYPEKLQQNIVKEDAKSEEFCVTSKTIIKQKSNMRGYLPVKGEISEFLTAFRCGTDFSYHPLDPRCLQEKQNKNLDYLSERESGVVFDFHESPLQFSIKSPKDYKNDENTSISSALLETSIENQIQRNKVGYLNLSKNKLSNLEDFIEFKMQLASDSLFKHLTTLKLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLSKNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQLQSIKINEIGVNISEKSLHFLRQLKKISLKGNSIADINEKFLENCDKIDSVNLSENKL 1226

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Planmine SMEST
Match: SMESG000066553.1 (SMESG000066553.1)

HSP 1 Score: 102.449 bits (254), Expect = 3.696e-21
Identity = 96/392 (24.49%), Postives = 180/392 (45.92%), Query Frame = 2

Query: 3212 IEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEI-IIPSKLPIQAPT----NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLI 4372
            I+++ W   +K  E  + Y L  WD +GQ  ++  H+ FL+ RA YLL++++ ++  E   L   L ++ C AP AP+FIVGTH DK+ ++   T   H +S          +P +    FV +    + +  L +KI+        +    + E  P+++L+    F++ L +   +   L  + VK L   +   + D E+  A++FLH+ G I +F   +  L +   +  QW+  ++   +++   N+ I+NG +          +H   K   +   E++ K  L++ E++D+ F     E   IP  LP + P        +   T + +  + F +LP G + R   R+S  + S           F +W+ G +++  D   L+
Sbjct: 1834 IDINSW--STKTGEINLQYSL--WDFAGQTLYYNTHQFFLTGRAIYLLIWNV-RQGFEHAGLDFWLNSVTCHAPSAPIFIVGTHSDKVDKSEIPTT--HFQSR---------YPSVVGFFFVSSLT-GKGVKELHDKII-----EETKGQPYIGELVPNAWLR----FEKELISQRSSADYLNWEAVKKLANNNA--IYDGEINQAIRFLHDLGSIQYFEFPL--LKDFVIINSQWLVDVMACVVSVK--NSIIENGKL----------EHSKIKLVWSKYPESIHKWLLRLTEIFDLTFSVPGQEFNFIPCLLPNKQPEFSWPEFVDFNQTREANMFYQFEYLPPGLFNRAQVRLSQFSDS-----------FIIWQNGSLLNKNDDKALL 2172

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Planmine SMEST
Match: SMESG000066553.1 (SMESG000066553.1)

HSP 1 Score: 102.449 bits (254), Expect = 3.984e-21
Identity = 96/392 (24.49%), Postives = 180/392 (45.92%), Query Frame = 2

Query: 3212 IEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEI-IIPSKLPIQAPT----NLSENLNTSKISRIFAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLI 4372
            I+++ W   +K  E  + Y L  WD +GQ  ++  H+ FL+ RA YLL++++ ++  E   L   L ++ C AP AP+FIVGTH DK+ ++   T   H +S          +P +    FV +    + +  L +KI+        +    + E  P+++L+    F++ L +   +   L  + VK L   +   + D E+  A++FLH+ G I +F   +  L +   +  QW+  ++   +++   N+ I+NG +          +H   K   +   E++ K  L++ E++D+ F     E   IP  LP + P        +   T + +  + F +LP G + R   R+S  + S           F +W+ G +++  D   L+
Sbjct: 1828 IDINSW--STKTGEINLQYSL--WDFAGQTLYYNTHQFFLTGRAIYLLIWNV-RQGFEHAGLDFWLNSVTCHAPSAPIFIVGTHSDKVDKSEIPTT--HFQSR---------YPSVVGFFFVSSLT-GKGVKELHDKII-----EETKGQPYIGELVPNAWLR----FEKELISQRSSADYLNWEAVKKLANNNA--IYDGEINQAIRFLHDLGSIQYFEFPL--LKDFVIINSQWLVDVMACVVSVK--NSIIENGKL----------EHSKIKLVWSKYPESIHKWLLRLTEIFDLTFSVPGQEFNFIPCLLPNKQPEFSWPEFVDFNQTREANMFYQFEYLPPGLFNRAQVRLSQFSDS-----------FIIWQNGSLLNKNDDKALL 2166

[Close]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Planmine SMEST
Match: SMESG000073246.1 (SMESG000073246.1)

HSP 1 Score: 101.293 bits (251), Expect = 9.317e-21
Identity = 149/587 (25.38%), Postives = 266/587 (45.32%), Query Frame = 2

Query: 2864 INLISPEIGNLSSLTLLDISHNPNLKSLPDEIGLLKGKNLNSLVR-DGLNLNIPKHISKNAQLREILKYYYDRLKHSVEYNXXXXXXXXXXXXXXTSVLNLLQGXXXXXXXXXXXXE------IEVSIWKVQSKLSEKAVDYKLTCWDISGQDEFFCNHECFLSQRAFYLLVFDITKETEEIHKLKPLLWNLKCQAPHAPVFIVGTHLDKMKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNKILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEVKDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWICSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVKQCLKVLELYDVVFRNSNNEI---IIPSKLPIQAPTNLSENLNTSKISRI----FAFSFLPTGFWPRLIARISVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLILEGKKDTEKNL-EIIEISVTKSELGIK-ILVQIVDCIDVLVEEWYAGLTDDDLHGNRIMNCYVRCLECAE 4576
            I  +   I  L +L +LD+S+NP L+ +  +I  +       LV    +++  P+ I++   L   LKY    L  +V  N  +L+ +GL   GKTS+L+ L+  +   K   +  E      I+++ W V     E     + + WD +GQD ++  H+ FLS++A Y++V+ + +  E    L   L ++ C + +APVF+VGT  D+++ +     C    S++ K      + +I   + VD+ +    I +LK K++     H   N   + +  PS+ L LE  F     ++      +T +E +++ +     + ++++K  +Q LH+ G I +F+   E L N   + PQWI  I+   +++  +N  I+NG I  ++ +    D F SK         L    L + E +D+ F +   E    I+P  L  + P       +   + +     + F FLP G + R+  R          LFD  + + KLW+ G+                  EKN   ++ +   KS L ++ I V+ V+ +  LV++   GL     HG R  N  + C +C E
Sbjct: 2015 IRYVPDSIQQLENLEILDLSYNPLLEKVSAQISSIISIKQLILVHCPSISVPPPEIIARGTSL-SYLKYL---LAKTVVCNRTKLMFVGLGEAGKTSLLHALRSDENSAKEIIEQQEKQVTDGIDITKWTVICHNEE----IQYSAWDFAGQDVYYNTHQFFLSEKAIYIVVWSVRQGIEH-GDLDFWLSSISCHSKYAPVFVVGTRCDQVQAD---MSCF---SSLKK-----RYSQIEDFILVDSLS-GTGIKDLKQKLI-----HVTLNLPYMHQAIPSTILDLENQF----TSIRSQKNYITYQEFQNIAISQ--GIFEKDVKSVIQILHDFGSIQYFD--TEILKNYVVINPQWIVDIMANVVSV--VNQKIKNG-IFYHENMKDVWDKFESK---------LFNWMLNLTEEFDLTFPHPTMEPKANIVPCLLSEEEPEIEWPKFSEQTLCKFYHINYKFEFLPAGLFNRIQVR----------LFDFTEAK-KLWKYGMYF----------------EKNGHHVLFMRENKSSLIVRAIGVRPVNVL-ALVDDVIKGLVKASFHGVR-YNLEISCPDCIE 2526

The following BLAST results are available for this feature:

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Human
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Celegans
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Fly
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Zebrafish
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Xenopus
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Mouse
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. UniProt/SwissProt
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. TrEMBL
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Cavefish
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Sea Lamprey
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Yeast
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Nematostella
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Medaka
BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Planmine SMEST

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
LRRK2	7.677e-130	29.28	leucine rich repeat kinase 2 [Source:HGNC Symbol;A...	[more]
LRRK1	5.387e-90	26.85	leucine rich repeat kinase 1 [Source:HGNC Symbol;A...	[more]
LRRK1	2.067e-27	27.05	leucine rich repeat kinase 1 [Source:HGNC Symbol;A...	[more]
STK36	2.693e-18	31.28	serine/threonine kinase 36 [Source:HGNC Symbol;Acc...	[more]
CDK1	1.477e-17	31.13	cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:...	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrk-1	6.070e-54	23.62	Leucine-rich repeat serine/threonine-protein kinas...	[more]
gck-3	7.790e-15	27.71	Germinal center kinase 3 [Source:UniProtKB/Swiss-...	[more]
gck-2	8.075e-15	28.63	Mitogen-activated protein kinase kinase kinase kin...	[more]
gck-3	8.563e-15	27.85	Germinal center kinase 3 [Source:UniProtKB/Swiss-...	[more]
C25A8.5	1.026e-13	25.45	Tyrosine-protein kinase [Source:UniProtKB/TrEMBL;...	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Lrrk	9.128e-31	25.91	gene:FBgn0038816 transcript:FBtr0112788	[more]
Lrrk	9.981e-31	25.91	gene:FBgn0038816 transcript:FBtr0334640	[more]
Lrrk	1.391e-30	25.91	gene:FBgn0038816 transcript:FBtr0334641	[more]
SAK	1.502e-17	28.62	gene:FBgn0026371 transcript:FBtr0078387	[more]
CG7236	2.592e-17	29.74	gene:FBgn0031730 transcript:FBtr0302950	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrk2	9.696e-117	29.16	leucine-rich repeat kinase 2 [Source:ZFIN;Acc:ZDB-...	[more]
lrrk1	1.272e-46	24.60	leucine-rich repeat kinase 1 [Source:ZFIN;Acc:ZDB-...	[more]
stk36	1.199e-17	32.82	serine/threonine kinase 36 (fused homolog, Drosoph...	[more]
pimr48	7.122e-17	28.68	Pim proto-oncogene, serine/threonine kinase, relat...	[more]
ascl1b	1.665e-16	25.81	si:ch211-210p4.6 [Source:NCBI gene;Acc:560440]	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hes2	8.915e-136	29.14	hes family bHLH transcription factor 2 [Source:Xen...	[more]
hes2	1.667e-135	29.14	hes family bHLH transcription factor 2 [Source:Xen...	[more]
hes2	1.826e-134	29.02	hes family bHLH transcription factor 2 [Source:Xen...	[more]
hes2	1.857e-134	29.02	hes family bHLH transcription factor 2 [Source:Xen...	[more]
hes2	2.136e-134	29.02	hes family bHLH transcription factor 2 [Source:Xen...	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Lrrk2	2.900e-131	29.17	leucine-rich repeat kinase 2 [Source:MGI Symbol;Ac...	[more]
Lrrk1	2.054e-89	26.86	leucine-rich repeat kinase 1 [Source:MGI Symbol;Ac...	[more]
Lrrk1	9.433e-49	28.95	leucine-rich repeat kinase 1 [Source:MGI Symbol;Ac...	[more]
Cdkl3	6.256e-19	33.68	cyclin-dependent kinase-like 3 [Source:MGI Symbol;...	[more]
Cdkl3	7.133e-19	33.84	cyclin-dependent kinase-like 3 [Source:MGI Symbol;...	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q5S006\|LRRK2_MOUSE	2.028e-130	29.17	Leucine-rich repeat serine/threonine-protein kinas...	[more]
sp\|Q5S007\|LRRK2_HUMAN	3.687e-129	29.28	Leucine-rich repeat serine/threonine-protein kinas...	[more]
sp\|Q38SD2\|LRRK1_HUMAN	2.587e-89	26.85	Leucine-rich repeat serine/threonine-protein kinas...	[more]
sp\|Q3UHC2\|LRRK1_MOUSE	1.437e-88	26.86	Leucine-rich repeat serine/threonine-protein kinas...	[more]
sp\|Q9TZM3\|LRK1_CAEEL	7.722e-53	23.62	Leucine-rich repeat serine/threonine-protein kinas...	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A516IJV2	0.000e+0	62.86	Leucine-rich repeat serine/threonine-protein kinas...	[more]
R7VFD9	1.944e-159	31.03	Uncharacterized protein OS=Capitella teleta OX=283...	[more]
A0A2T7NTI5	5.400e-158	31.19	Uncharacterized protein OS=Pomacea canaliculata OX...	[more]
A0A2R2MN78	1.881e-152	30.50	leucine-rich repeat serine/threonine-protein kinas...	[more]
A0A2R2MNR6	4.226e-152	30.50	leucine-rich repeat serine/threonine-protein kinas...	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrk2	3.369e-112	30.97	leucine-rich repeat kinase 2 [Source:ZFIN;Acc:ZDB-...	[more]
lrrk1	2.318e-78	25.63	leucine-rich repeat kinase 1 [Source:ZFIN;Acc:ZDB-...	[more]
stk36	6.896e-18	33.16	serine/threonine kinase 36 [Source:NCBI gene;Acc:1...	[more]
map3k19	2.617e-17	25.64	mitogen-activated protein kinase kinase kinase 19 ...	[more]
cdk1	2.620e-17	30.69	cyclin dependent kinase 1 [Source:NCBI gene;Acc:10...	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000001592.1	1.199e-63	30.22	pep scaffold:Pmarinus_7.0:GL477300:73535:87647:-1 ...	[more]
ENSPMAT00000001591.1	1.565e-60	31.86	pep scaffold:Pmarinus_7.0:GL477300:68165:86851:-1 ...	[more]
ENSPMAT00000004441.1	8.123e-29	22.03	pep scaffold:Pmarinus_7.0:GL477554:92318:114375:1 ...	[more]
STK36	4.909e-21	34.54	serine/threonine kinase 36 [Source:HGNC Symbol;Acc...	[more]
stk33	1.856e-18	29.59	serine/threonine kinase 33 [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
SNF1	1.948e-14	30.00	AMP-activated S/T protein kinase; forms a complex ...	[more]
CMK1	4.548e-14	25.65	Calmodulin-dependent protein kinase; may play a ro...	[more]
STE20	2.219e-13	27.98	Cdc42p-activated signal transducing kinase; involv...	[more]
STE11	2.444e-13	29.45	Signal transducing MEK kinase; involved in pheromo...	[more]
DUN1	3.407e-13	30.88	Cell-cycle checkpoint S/T protein kinase; required...	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO37102	3.120e-108	27.70	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31971	6.697e-59	30.69	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31970	2.272e-25	36.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31590	5.595e-25	34.55	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27465	4.325e-24	32.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrk2	1.804e-115	28.28	leucine rich repeat kinase 2 [Source:NCBI gene;Acc...	[more]
cdk1	2.422e-16	30.69	cyclin dependent kinase 1 [Source:NCBI gene;Acc:10...	[more]
cdk6	8.942e-15	28.11	cyclin dependent kinase 6 [Source:NCBI gene;Acc:10...	[more]
si:ch211-22d5.2	9.454e-15	28.83	serine/threonine-protein kinase NIM1-like [Source:...	[more]
si:ch211-22d5.2	9.454e-15	28.83	serine/threonine-protein kinase NIM1-like [Source:...	[more]

BLAST of Leucine-rich repeat serine/threonine-protein kinase 2-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000056130.1	0.000e+0	99.37	SMESG000056130.1	[more]
SMESG000056130.1	0.000e+0	97.89	SMESG000056130.1	[more]
SMESG000066553.1	3.696e-21	24.49	SMESG000066553.1	[more]
SMESG000066553.1	3.984e-21	24.49	SMESG000066553.1	[more]
SMESG000073246.1	9.317e-21	25.38	SMESG000073246.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30006689 ID=SMED30006689|Name=Leucine-rich repeat serine/threonine-protein kinase 2-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=6733bp
CACATATATCATTCAGATATAGGTACATTTGTGTTGGAAAATCTTAAAAA
ATATAATATGAAAGAGATTTTAATTTATGGATTTAAAATGTTATATTTAT
TTGTATCTTTATCAAAATCATTGAAGAGACTTCTTAATGAATCTGATCAA
GAGTCTTGGATACAATTTATATTGGATGTTTTAAAAAATAATTTACAATG
CTCAGAAACAATTAACTGGTCGTTTTCTGTGATAAATCGCATTATTGTAT
TGGATCCAAATTTAGTTCGTTTGATTGAAAATAAAGAATTTTTACAGGAT
ACATCTTTGGACACTCTGCTCCTTCAAATCTTCTATTCACAAACTGAATT
ATCAATTTCAACGCTCTGTTCATGTTTTGAAATCACTTCAATCCTATCGA
AATACTCAGAAAAGATTCAAAATCATTTTCTAGAAAGTCAAATTCAAACT
CTCATTCATTTAATGGTAGTCAGATGTCTTCAAACAAAATCATTAAGCAA
AGAAATTGAATGCCAAATTAGACTGGCAGCGACAAATGCTATGAAGTCTC
TGATTTTATATAACTTGCCTGCGAAGGAGTTATTTTATAATGAACAAACT
CAATACGAAGACGCCAAGAGGTTTTTAGTGAGCTGTTGCCAACATAATCA
TGATGATTGTAAATACGAAGAGTGTCTTGCTGCAACTTTATTGTTCTTGG
CATGTCTCGTGGAATACAATTCAATCAAATATGACCTTATGCAAACTTTA
CAATCAACATTAATGAAATTGTTATCATGTGAAAGATGTTCAATGAGTCC
AACTATAATTGAAGCCTTCCAAGAACTATTAATAGTTTTATCAGGATTTG
AACACGAAACCCTCTTTATATTGGACATACTCTCAATAAGAGAATGCTGT
GAATTGGCGAGTAAATTTCTAAACTTTTATGCTATTCAAAAAAATACAGT
AATATTTATACAACTGAATTCATCTAGCATTAACAAAGTGGAAAAATTAA
AAATTCTTCAGATTATCGGTGAAACAATTTTCCGAGCAACTTCTTTGTTT
AAAAACTGTCTAATAATTCGTGCAGAGGCTTGTGTTTTAATACAAATTTT
ATTAAAACAATATCCAGAGTTTTCCCCGATATGTGTTGAAAATAATTTGG
ACAAGTTCCTTTTTGAGACTATTAATATGAATCAAAATCCAGATTTGATT
AAAATTGGTTTACAAGCTTTTTATGTACTTACAGAATTACAAGAAAATAG
AGATTTAATTTTAATTAAGGCTATTAAGGAATCCAAGTTGAAGTTGGTTC
AATGTCTAATTGCAATTGGAAGTGATCTAGCAAAAGTCTCAAAAGATGCT
TTATTGTCAGCCGTTAAACAAAAGGATGAAGCCATCAGTTTCCAATTAAT
GTCACATTTAGTTAATAATGGATGTAAGCCAGAGTTTTATCTTATTACCT
GTTGTTTTGACACAAATAATTACAAAAATGCAATTGTCTTATTGAGACAT
TATGGGATTAATGACTCAACTGAAGGAAAAATAATAAATTGGAGTGATTT
GGGAATGAGACATTTCCATATTTCATGGTTGGAAGATTTGTGTGAAAAAC
AAAAACTACAAATCGATCCGAATGTTATCTGGTTATCCAAGAGAATTAAG
CAGGAGTCTAAAAACCGGATGTTGCTGAGACAAAATTATGAAAAGTATCA
AAATTCACATGTGAAATCGTATCGATATCCGGAAACGCAAATGAGAACTT
TGGACAAGGATATTGCAGGTCACAAAAACTACACTCGAATAAATAATGGA
ATACCAATCCGAATATCAAATATTGGCAAGCAAAACTTGTTCTATAATAG
TTCCCTGCATGAAAATTCACATAATCTTATAAATTATCCTGGAAATTATT
CACTGCGATATCCTGAAAAGCTCCAACAAAATATTGTGAAAGAAGATGCA
AAATCAGAAGAATTTTGTGTTACCAGTAAAACAATAATAAAACAGAAGTC
AAACATGCGGGGATATCTGCCTGTCAAGGGTGAAATCAGTGAATTTTTAA
CGGCTTTCCGATGTGGAACGGATTTTTCATATCATCCCTTGGACCCAAGA
TGTTTACAAGAAAAACAAAATAAAAATTTGGATTATCTGTCAGAAAGAGA
AAGCGGAGTTGTATTTGATTTCCATGAATCCCCTTTACAGTTTTCAATTA
AGTCACCCAAAGACTACAAAAACGATGAAAATACCTCGATAAGTTCTGCT
TTATTGGAAACGAGTATAGAAAACCAAATTCAGAGAAATAAAGTCGGTTA
TTTGAATTTATCAAAAAATAAATTGTCAAATCTGGAAGACTTTATTGAAT
TCAAAATGCAATTGGCATCGGATTCTCTTTTTAAGCATTTGACAACATTA
AAATTGGAAAAGAATTCAATAAAATCTATTCCAGAAAGTGCTTTTCAAAA
TATGGAACAGTTGAAAATTTTGGATTTGAGTGAAAACAGATTGACCAAAG
TCCCTTGGTTTGTGTTCAAATATTCTCCATTGGAGAACTTGAATCTATCT
AAAAATAATATAAAACAGTTTTGTTTATCAAAAACGGACAAAACTACGCT
GAAGTCATTTAGAAAAACAAACTTTCTTTCAATAATTAATTTATCAAATA
ATAAATTTACCGATTTCGACATAAATTCGTTTGATGTTTTTCAACAACTT
CAAAGCATTAAAATAAATGAAATTGGTTTGAATATTTCGGAGAAATCTTT
GCATTTTCTTAGGCAGCTGAAAAAGATTTCATTGAAAGGAAATTCCATTG
CAGATATTAATGAAAAGTTTTTGGAAAATTGTGACAAAATAGATTCAGTA
AATTTGAGTGAAAATAAACTTGATTTCACCTGAAATAGGCAATTTGTCGA
GTCTAACACTGTTGGATATCAGCCATAATCCAAATTTAAAAAGCTTGCCG
GATGAAATTGGACTCCTTAAAGGAAAGAATCTTAATAGCTTAGTAAGAGA
TGGCTTAAATTTAAATATTCCAAAACACATCAGTAAAAATGCCCAATTGC
GAGAGATACTGAAATACTATTATGATAGATTGAAGCATTCTGTGGAATAT
AATGGATTGCGACTGGTGGTTTTAGGATTAAAGGGAAGGGGTAAAACATC
TGTTCTTAACTTACTTCAAGGATCGAAATTAAAACCGAAAAATAACAATA
AATCCTCAGAAATTGAAGTTTCAATTTGGAAAGTTCAATCAAAACTTTCT
GAGAAAGCAGTTGACTACAAGCTAACATGTTGGGATATTAGCGGTCAAGA
TGAGTTCTTTTGCAATCATGAATGCTTCTTATCTCAAAGAGCTTTTTATT
TGTTAGTTTTTGATATTACCAAAGAAACAGAAGAAATCCACAAATTGAAG
CCTTTGTTATGGAACTTGAAATGTCAAGCTCCTCATGCTCCAGTGTTTAT
TGTTGGTACTCACCTTGATAAAATGAAAGAAAATAATAGGAAAACTCAAT
GTAGACATATGGAAAGCAACATTTTAAAGCTTTGCAGTACTCCGGGATTT
CCAAAAATTTCAAAGATTGTCTTTGTTGATGCGACAAATTTTAATCAAAC
AATAACAAATTTAAAAAACAAAATATTGACAGTGTTGAACGATCACACCA
TTCAAAATGACCATTTGTTATTTGAGAAACAGCCTAGTAGTTATTTAAAG
CTAGAAGAATTATTTCAAGAAGCATTGAAAACTTTACCAGAGAATTGTCC
CATTTTAACCGAGAAAGAAGTCAAAGATTTGGTGGTGAAACATAAATTAG
ATTTAAATGATGAAGAATTGAAACTGGCCGTTCAATTCCTACACAATTGC
GGAGTAATTGTCCATTTCAACGACACTATGGAAAATTTAAATAATCTTTA
CTTTTTGAAACCCCAATGGATTTGTTCTATTATAATTAAAACAATTACAA
TGAATCGTTTGAATACTTTTATCCAAAATGGATCTATCAGTCTGAATGAT
TTTCTTTCATTGTTTAAGGATCACTTTTTTTCAAAAGAAACGGAAAATTT
CAAAAAAGAAACTCTTGTCAAGCAGTGCTTGAAAGTTCTTGAATTATACG
ATGTCGTTTTCCGAAATTCAAATAACGAAATAATCATTCCTTCAAAATTA
CCCATTCAGGCGCCGACAAATTTATCAGAAAATTTAAATACGTCAAAGAT
TAGTAGGATATTTGCATTCTCATTCTTACCAACTGGGTTTTGGCCGCGAC
TTATTGCAAGAATCAGCGTTTTGGCCAAATCATTCAAACATCTCTTTGAC
ATTTGTAAATTAGAGTTCAAGTTGTGGAGAACTGGAGTCATTATATCTAT
GGAGGATTCGATTTATCTAATATTGGAAGGTAAGAAAGATACTGAAAAGA
ACTTGGAAATCATCGAAATATCTGTCACGAAGAGTGAGTTGGGAATAAAA
ATTCTTGTTCAAATAGTCGACTGTATTGATGTACTGGTAGAGGAATGGTA
CGCGGGACTTACTGATGACGATCTTCATGGGAATCGGATTATGAATTGTT
ACGTTCGTTGCTTAGAATGTGCTGAACAAGTTCCTCTGTTAGATATTGCC
AGTATATCTTTGCGATCTGATCATTTTTTTTGTACGAGTAAACATCAAAA
CCAATTTCGAATAGTAGTTCCAGATATTGTTCTAGGAGATCTCCCCGATG
ATATTCTTATCAATCCATCCGATTTAGAGGTTAATACAAGTAAAGATAAT
ATGTTTGGAGTTGGAGGCAATGGATCCGTATTCAAGGGATATTATAAAGG
AAAATGTTGTGCGGTTAAGTACATAAATGTGGTTGAGCACTCAAATGATG
CGCCATCTTATCGATTATTACGCCAAGAAATTGATATACTAAGGAGGTTC
CAGCATCCGTCAATAGTGAGTTTGCTAGCTGTTGATCGCAAACGAATAGT
ATTGGAATTTGCACCTTTCAAAGATTTAAAATGCGTTTTCCAACATTACA
TAAACCTGTCCTCTGTGCTTCTTCAACGGATCGCATACCAAGTGATCAGC
GGAATTCAGTTTCTACATTTTAACAATATTATCTATCGAGATATTAAAAT
GCAAAACGTTTTGGTGTTTAGTTTGGAACTTTCTTCAAAGATAAATGTAA
AACTCGCAGATTACGGAATATCAAGAGAATTAGCTCCCTTTGGTTTTGTT
ATTCCTCAAGGGACGCCTGGATATCAAGCTCCAGAAGTACTTGAAAGATG
TATTTCATATAAACTTCCTGCAGACATCTTTTCTTTCGGTATTCTTCTGT
TTAATATAGGAACTATGGGTCATCATCCAGCGGAATTTAGAGCTCATTGG
CGAGCCGGTAAGCAAATAGACCTGATTTCTGAGCACAGCAGTAATAGCTG
GCCAAGAATGCAGGATTGTATTCATAAATGCACAAAGCTAGTTCCGGAAG
ATCGACCGAATGCTGAAGATATTTCAAAATTTATCCTTTGTCCTTCTTTT
GTAGCTATAAAATATGTATGGCCATTGACTAGGCAGACACGAATCGAATG
CATGACCACAATGATGAATGAAAGCAACATATTAAATGTTTTTTTAGCAA
ATGGTAATAAATTTAAACAAGAAGTTCGGTCAATTGATATAAAATCTGGA
CAATCAAAGGGGAAATCATTTTGCAAAGAAGTTGATTCAAACAGAATATT
ATCTATGATGGTTTTTGAAAGTATAATATTTTTGGGTACTCAAAATGGCC
AGCTGTGGACATATGATCATTTAGAAAACAAATTTGAGAACACAAATCTT
GTTTTACCTGATGCCATCCTTTGTATGGTTATGAAGAGCTACGTTGACTA
TTTCAAAGTGTTGATGATGGGGTTAGCTAATGGGACAATCTATTACAAAT
TGGGCTATACTTCTATTCAAGACATTAATTCAGAAATATTAAGTAAACTG
CCACTTTCGGATGCTCCAGTAACTAATATTTTCTTGATTGATGATTATAT
ATTTGCCACTTCGGGATTTGTGATATACAAAATAAATCTTTCCATCGATA
CTGAAAGATTTACGGCAGTAAAATTGATAGAGATCGACTCAAGTGATCAA
GACCGATTGATAAAATGTTTCTGTCCCTTTACAGAAAATACTAACGGAGA
TTTGATAATAAGCTTTTATTTCACAATTAGAAATGAATCCTTAATCTATA
ATTTTGATGACCAAGGTATTCAACTGAAACCAGCGGTAGATTGCAAGGAA
TTAATAAAAGAGAAATTGAATATAAATAGTAAAAGTTATTCGTGTAGAAT
AATGTGTATGACCATATGGTCAGGAGATCGCTATTTATGTGCCGGAACCG
GAAATGGTTACTTAATAATTATTGATCAAGAAATTAATTACACTGTGGTG
CTCAGTTTATTTAAAAATCACATTATTTGTATTCAACACTCAAAGTTACA
CAATAAACACGATAAACCCGATAAAGAAATTGTCAGTGGTCCTACCCCTG
AAAAACCCGATGTCACAGACCACTTAATAAATTGTACCGAAACTTTTGAA
AGTTCCGCTGAGAATACAGGCTTAATAATTGTTGGAAATGGATACAAATC
AATTGAAGAGGACTTTGACGGGGCAGTTTTAATTGTTTTAAGCGATGATA
TTTCAAATATTTCCAGACAATTGGAAGAACATATTAACTCAAGAAATCAC
ATTTTGTAAATAACATTTTTTTGAAATAAAAAT

protein sequence of SMED30006689-orf-1

>SMED30006689-orf-1 ID=SMED30006689-orf-1|Name=SMED30006689-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=961bp
HIYHSDIGTFVLENLKKYNMKEILIYGFKMLYLFVSLSKSLKRLLNESDQ
ESWIQFILDVLKNNLQCSETINWSFSVINRIIVLDPNLVRLIENKEFLQD
TSLDTLLLQIFYSQTELSISTLCSCFEITSILSKYSEKIQNHFLESQIQT
LIHLMVVRCLQTKSLSKEIECQIRLAATNAMKSLILYNLPAKELFYNEQT
QYEDAKRFLVSCCQHNHDDCKYEECLAATLLFLACLVEYNSIKYDLMQTL
QSTLMKLLSCERCSMSPTIIEAFQELLIVLSGFEHETLFILDILSIRECC
ELASKFLNFYAIQKNTVIFIQLNSSSINKVEKLKILQIIGETIFRATSLF
KNCLIIRAEACVLIQILLKQYPEFSPICVENNLDKFLFETINMNQNPDLI
KIGLQAFYVLTELQENRDLILIKAIKESKLKLVQCLIAIGSDLAKVSKDA
LLSAVKQKDEAISFQLMSHLVNNGCKPEFYLITCCFDTNNYKNAIVLLRH
YGINDSTEGKIINWSDLGMRHFHISWLEDLCEKQKLQIDPNVIWLSKRIK
QESKNRMLLRQNYEKYQNSHVKSYRYPETQMRTLDKDIAGHKNYTRINNG
IPIRISNIGKQNLFYNSSLHENSHNLINYPGNYSLRYPEKLQQNIVKEDA
KSEEFCVTSKTIIKQKSNMRGYLPVKGEISEFLTAFRCGTDFSYHPLDPR
CLQEKQNKNLDYLSERESGVVFDFHESPLQFSIKSPKDYKNDENTSISSA
LLETSIENQIQRNKVGYLNLSKNKLSNLEDFIEFKMQLASDSLFKHLTTL
KLEKNSIKSIPESAFQNMEQLKILDLSENRLTKVPWFVFKYSPLENLNLS
KNNIKQFCLSKTDKTTLKSFRKTNFLSIINLSNNKFTDFDINSFDVFQQL
QSIKINEIGLNISEKSLHFLRQLKKISLKGNSIADINEKFLENCDKIDSV
NLSENKLDFT*

protein sequence of SMED30006689-orf-2

>SMED30006689-orf-2 ID=SMED30006689-orf-2|Name=SMED30006689-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1079bp
MKENNRKTQCRHMESNILKLCSTPGFPKISKIVFVDATNFNQTITNLKNK
ILTVLNDHTIQNDHLLFEKQPSSYLKLEELFQEALKTLPENCPILTEKEV
KDLVVKHKLDLNDEELKLAVQFLHNCGVIVHFNDTMENLNNLYFLKPQWI
CSIIIKTITMNRLNTFIQNGSISLNDFLSLFKDHFFSKETENFKKETLVK
QCLKVLELYDVVFRNSNNEIIIPSKLPIQAPTNLSENLNTSKISRIFAFS
FLPTGFWPRLIARISVLAKSFKHLFDICKLEFKLWRTGVIISMEDSIYLI
LEGKKDTEKNLEIIEISVTKSELGIKILVQIVDCIDVLVEEWYAGLTDDD
LHGNRIMNCYVRCLECAEQVPLLDIASISLRSDHFFCTSKHQNQFRIVVP
DIVLGDLPDDILINPSDLEVNTSKDNMFGVGGNGSVFKGYYKGKCCAVKY
INVVEHSNDAPSYRLLRQEIDILRRFQHPSIVSLLAVDRKRIVLEFAPFK
DLKCVFQHYINLSSVLLQRIAYQVISGIQFLHFNNIIYRDIKMQNVLVFS
LELSSKINVKLADYGISRELAPFGFVIPQGTPGYQAPEVLERCISYKLPA
DIFSFGILLFNIGTMGHHPAEFRAHWRAGKQIDLISEHSSNSWPRMQDCI
HKCTKLVPEDRPNAEDISKFILCPSFVAIKYVWPLTRQTRIECMTTMMNE
SNILNVFLANGNKFKQEVRSIDIKSGQSKGKSFCKEVDSNRILSMMVFES
IIFLGTQNGQLWTYDHLENKFENTNLVLPDAILCMVMKSYVDYFKVLMMG
LANGTIYYKLGYTSIQDINSEILSKLPLSDAPVTNIFLIDDYIFATSGFV
IYKINLSIDTERFTAVKLIEIDSSDQDRLIKCFCPFTENTNGDLIISFYF
TIRNESLIYNFDDQGIQLKPAVDCKELIKEKLNINSKSYSCRIMCMTIWS
GDRYLCAGTGNGYLIIIDQEINYTVVLSLFKNHIICIQHSKLHNKHDKPD
KEIVSGPTPEKPDVTDHLINCTETFESSAENTGLIIVGNGYKSIEEDFDG
AVLIVLSDDISNISRQLEEHINSRNHIL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR015943	WD40/YVTN_repeat-like_dom_sf
IPR036322	WD40_repeat_dom_sf
IPR003591	Leu-rich_rpt_typical-subtyp
IPR032675	LRR_dom_sf
IPR001611	Leu-rich_rpt
IPR013319	GH11/12
IPR000719	Prot_kinase_dom
IPR032171	COR
IPR013684	MIRO-like
IPR027417	P-loop_NTPase
IPR008271	Ser/Thr_kinase_AS
IPR020859	ROC_dom
IPR017986	WD40_repeat_dom
IPR011009	Kinase-like_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004672	protein kinase activity
GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0000149	SNARE binding
GO:0000166	nucleotide binding
GO:0001948	glycoprotein binding
GO:0003779	actin binding
GO:0003924	GTPase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004708	MAP kinase kinase activity
GO:0004871	signal transducer activity
GO:0005096	GTPase activator activity
GO:0017075	syntaxin-1 binding
GO:0030159	receptor signaling complex scaffold activity
GO:0030276	clathrin binding
GO:0032403	protein complex binding
GO:0034211	GTP-dependent protein kinase activity
GO:0015631	tubulin binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0017048	Rho GTPase binding
GO:0036479	peroxidase inhibitor activity
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0044325	ion channel binding
GO:0051018	protein kinase A binding
GO:1904713	beta-catenin destruction complex binding

Vocabulary: **biological process**
Term	Definition
GO:0006468	protein phosphorylation
GO:0007264	small GTPase mediated signal transduction
GO:0006897	endocytosis
GO:0006914	autophagy
GO:0006979	response to oxidative stress
GO:0007005	mitochondrion organization
GO:0007030	Golgi organization
GO:0007040	lysosome organization
GO:0007528	neuromuscular junction development
GO:0008340	determination of adult lifespan
GO:0009267	cellular response to starvation
GO:0000165	MAPK cascade
GO:0000186	activation of MAPKK activity
GO:0000187	activation of MAPK activity
GO:0001933	negative regulation of protein phosphorylation
GO:0001934	positive regulation of protein phosphorylation
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0019722	calcium-mediated signaling
GO:0021772	olfactory bulb development
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb
GO:0030154	cell differentiation
GO:0031398	positive regulation of protein ubiquitination
GO:0032091	negative regulation of protein binding
GO:0032092	positive regulation of protein binding
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034260	negative regulation of GTPase activity
GO:0034599	cellular response to oxidative stress
GO:0034613	cellular protein localization
GO:0035556	intracellular signal transduction
GO:0035564	regulation of kidney size
GO:0035640	exploration behavior
GO:0010506	regulation of autophagy
GO:0010508	positive regulation of autophagy
GO:0010738	regulation of protein kinase A signaling
GO:0010955	negative regulation of protein processing
GO:0014041	regulation of neuron maturation
GO:0016242	negative regulation of macroautophagy
GO:0016310	phosphorylation
GO:0035641	locomotory exploration behavior
GO:0035751	regulation of lysosomal lumen pH
GO:0036465	synaptic vesicle recycling
GO:0040012	regulation of locomotion
GO:0042391	regulation of membrane potential
GO:0043068	positive regulation of programmed cell death
GO:0043547	positive regulation of GTPase activity
GO:0046039	GTP metabolic process
GO:0046777	protein autophosphorylation
GO:0048312	intracellular distribution of mitochondria
GO:0048812	neuron projection morphogenesis
GO:0051646	mitochondrion localization
GO:0051900	regulation of mitochondrial depolarization
GO:0051966	regulation of synaptic transmission, glutamatergic
GO:0060079	excitatory postsynaptic potential
GO:0060159	regulation of dopamine receptor signaling pathway
GO:0060161	positive regulation of dopamine receptor signaling pathway
GO:0060828	regulation of canonical Wnt signaling pathway
GO:0061001	regulation of dendritic spine morphogenesis
GO:0070997	neuron death
GO:0071287	cellular response to manganese ion
GO:0071407	cellular response to organic cyclic compound
GO:0072593	reactive oxygen species metabolic process
GO:0090263	positive regulation of canonical Wnt signaling pathway
GO:0090394	negative regulation of excitatory postsynaptic potential
GO:1901214	regulation of neuron death
GO:1901215	negative regulation of neuron death
GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1902499	positive regulation of protein autoubiquitination
GO:1902692	regulation of neuroblast proliferation
GO:1902803	regulation of synaptic vesicle transport
GO:1902902	negative regulation of autophagosome assembly
GO:1903125	negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation
GO:1903206	negative regulation of hydrogen peroxide-induced cell death
GO:1903215	negative regulation of protein targeting to mitochondrion
GO:1903351	cellular response to dopamine
GO:1904887	Wnt signalosome assembly
GO:1905279	regulation of retrograde transport, endosome to Golgi
GO:1905289	regulation of CAMKK-AMPK signaling cascade
GO:2000172	regulation of branching morphogenesis of a nerve
GO:2000300	regulation of synaptic vesicle exocytosis

Vocabulary: **cellular component**
Term	Definition
GO:0008021	synaptic vesicle
GO:0005615	extracellular space
GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0005743	mitochondrial inner membrane
GO:0005759	mitochondrial matrix
GO:0005764	lysosome
GO:0005768	endosome
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005798	Golgi-associated vesicle
GO:0005802	trans-Golgi network
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0005902	microvillus
GO:0030054	cell junction
GO:0030424	axon
GO:0030425	dendrite
GO:0030426	growth cone
GO:0030529	intracellular ribonucleoprotein complex
GO:0030672	synaptic vesicle membrane
GO:0031410	cytoplasmic vesicle
GO:0031966	mitochondrial membrane
GO:0032473	cytoplasmic side of mitochondrial outer membrane
GO:0032839	dendrite cytoplasm
GO:0016020	membrane
GO:0016234	inclusion body
GO:0042995	cell projection
GO:0043005	neuron projection
GO:0043025	neuronal cell body
GO:0043195	terminal bouton
GO:0043204	perikaryon
GO:0043231	intracellular membrane-bounded organelle
GO:0044753	amphisome
GO:0044754	autolysosome
GO:0045121	membrane raft
GO:0045202	synapse
GO:0070062	extracellular exosome
GO:0097487	multivesicular body, internal vesicle
GO:0098794	postsynapse
GO:0099400	caveola neck
GO:1990909	Wnt signalosome

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000719	Protein kinase domain	SMART	SM00220	serkin_6	coord: 422..677 e-value: 5.7E-36 score: 135.5
IPR000719	Protein kinase domain	PFAM	PF00069	Pkinase	coord: 425..668 e-value: 4.9E-37 score: 127.7
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 422..677 score: 31.877
IPR015943	WD40/YVTN repeat-like-containing domain superfamily	GENE3D	G3DSA:2.130.10.10		coord: 703..1004 e-value: 1.7E-5 score: 26.2
None	No IPR available	GENE3D	G3DSA:1.10.510.10		coord: 421..702 e-value: 3.9E-45 score: 156.1
None	No IPR available	PANTHER	PTHR23257:SF740	LEUCINE-RICH REPEAT SERINE/THREONINE-PROTEIN KINASE 1	coord: 60..264 coord: 331..689
None	No IPR available	PANTHER	PTHR23257	SERINE-THREONINE PROTEIN KINASE	coord: 60..264
None	No IPR available	PANTHER	PTHR23257	SERINE-THREONINE PROTEIN KINASE	coord: 331..689
IPR032171	C-terminal of Roc (COR) domain	PFAM	PF16095	COR	coord: 71..291 e-value: 7.2E-25 score: 87.9
IPR008271	Serine/threonine-protein kinase, active site	PROSITE	PS00108	PROTEIN_KINASE_ST	coord: 536..548
IPR011009	Protein kinase-like domain superfamily	SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	coord: 426..686
IPR036322	WD40-repeat-containing domain superfamily	SUPERFAMILY	SSF50978	WD40 repeat-like	coord: 720..990