PDZ domain-containing protein

Overview


Name	PDZ domain-containing protein
Smed ID	SMED30006669
Length (bp)	2472

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of PDZ domain-containing protein (SMED30006669) t-SNE clustered cells

Violin plots show distribution of expression levels for PDZ domain-containing protein (SMED30006669) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PDZ domain-containing protein (SMED30006669) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PDZ domain-containing protein (SMED30006669) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30006669

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30006669	h1SMcG0022388	dd_Smed_v4_17308_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30006669	h1SMcG0022388	dd_Smed_v4_17308_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30006669	h1SMcG0022388	dd_Smed_v4_17308_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
reproductive organ	SMED30006669	h1SMcG0022388	Contig35698	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30006669	h1SMcG0022388	Contig35698	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30006669	h1SMcG0022387	Contig35698	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30006669	h1SMcG0022387	Contig35698	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: WHRN (whirlin [Source:HGNC Symbol;Acc:HGNC:16361])

HSP 1 Score: 79.7221 bits (195), Expect = 9.996e-15
Identity = 60/180 (33.33%), Postives = 89/180 (49.44%), Query Frame = 1

Query: 1846 DEIRKINKDNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISR--KTISTPKEYISMQYNIPKEEIIKLAGNK-------LKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            +E+R + +      L +    + +  QT+ E    +  VD  + E     R  +++ST K   S +  +P+ E      NK          LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG+ L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  385 NEVRALPQTRTASTLSQ----LSDSGQTLSE----DSGVDAGEAEASAPGRGRQSVST-KSRSSKE--LPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFN 553

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: WHRN (whirlin [Source:HGNC Symbol;Acc:HGNC:16361])

HSP 1 Score: 79.337 bits (194), Expect = 1.005e-14
Identity = 60/180 (33.33%), Postives = 89/180 (49.44%), Query Frame = 1

Query: 1846 DEIRKINKDNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISR--KTISTPKEYISMQYNIPKEEIIKLAGNK-------LKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            +E+R + +      L +    + +  QT+ E    +  VD  + E     R  +++ST K   S +  +P+ E      NK          LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG+ L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  353 NEVRALPQTRTASTLSQ----LSDSGQTLSE----DSGVDAGEAEASAPGRGRQSVST-KSRSSKE--LPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFN 521

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: WHRN (whirlin [Source:HGNC Symbol;Acc:HGNC:16361])

HSP 1 Score: 79.337 bits (194), Expect = 1.664e-14
Identity = 58/179 (32.40%), Postives = 85/179 (47.49%), Query Frame = 1

Query: 1843 FDEIRKINKDNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISRKTISTPKEYISMQYNIPKEEIIKLAGNK-------LKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
             +E+R + +      L +    + +  QT+ E    +  VD  + E     R   S   +  S +  +P+ E      NK          LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG+ L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  735 VNEVRALPQTRTASTLSQ----LSDSGQTLSE----DSGVDAGEAEASAPGRGRQSVSTKSRSSK-ELPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFN 904

HSP 2 Score: 65.855 bits (159), Expect = 2.773e-10
Identity = 77/340 (22.65%), Postives = 143/340 (42.06%), Query Frame = 1

Query:  646 SIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHP---PLNYTICL---DHSRLKPIELLKDVSQE-----------IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP------------MTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQR-NQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNTLRVNDRMTF 1575
             IY++ V+  +L ++  +     ++G ++ ++N +  +++   E +  L  S  L L +   G        N  + Y W+D     I  P   P  +   L   +  R   + LL+   ++           +G+ I GG +Y LGIYI+ + PGS     G + GD+IL++N  SF         EA   L       + V    +LP             + +I+E  + S G      D+ +   +K  F+KG   +Q+T +SL   +   LE Q     ++Q+   + + L++Y    ++V  LV A+   ++      L++ +  T+   D   F
Sbjct:  165 GIYVSLVEPGSLAEKEGL-----RVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTN--HIYTWVDPQGRSISPPSGLPQPHGGALRQQEGDRRSTLHLLQGGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAEGSGLKVGDQILEVNGRSFLNI---LHDEAVRLLKSSRHLILTVKDVGRLPHARTTVDETKWIASSRIRETMANSAG---FLGDLTTEGINKPGFYKGPAGSQVTLSSLGNQTRVLLEEQARHLLNEQEHATMAYYLDEYRGGSVSVEALVMALFKLLNTHAKFSLLSEVRGTISPQDLERF 491

HSP 3 Score: 53.9138 bits (128), Expect = 1.441e-6
Identity = 32/96 (33.33%), Postives = 53/96 (55.21%), Query Frame = 1

Query:  991 IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP---MTDKIQ---EPRSRSV 1260
            +G +I GG ++ +GIY+S ++PGS+    G + GD+IL++N  S         AEA  AL       + VYS  ++P   +T+ I    +P+ RS+
Sbjct:  152 LGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLA---RVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTNHIYTWVDPQGRSI 244

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: WHRN (whirlin [Source:HGNC Symbol;Acc:HGNC:16361])

HSP 1 Score: 78.5666 bits (192), Expect = 2.481e-14
Identity = 60/181 (33.15%), Postives = 89/181 (49.17%), Query Frame = 1

Query: 1843 FDEIRKINKDNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISR--KTISTPKEYISMQYNIPKEEIIKLAGNK-------LKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
             +E+R + +      L +    + +  QT+ E    +  VD  + E     R  +++ST K   S +  +P+ E      NK          LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG+ L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  393 VNEVRALPQTRTASTLSQ----LSDSGQTLSE----DSGVDAGEAEASAPGRGRQSVST-KSRSSKE--LPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFN 562

HSP 2 Score: 58.151 bits (139), Expect = 4.726e-8
Identity = 50/190 (26.32%), Postives = 86/190 (45.26%), Query Frame = 1

Query:  955 KPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTDKIQEPRSRSVGRSRRKDDMYSV------LESKGMFHKGQRNQLTHTSLTQPSLGN-----LEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAI 1491
            K + L+    + +G+ I GG +Y LGIYI+ + PGS     G + GD+IL++N  SF         EA   L       + V    +LP      +  ++ +  SR ++ M +       L ++G+   G       + +T  SLGN     LE Q     ++Q+   + + L++Y    ++V  LV A+
Sbjct:    6 KKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAEGSGLKVGDQILEVNGRSFLNI---LHDEAVRLLKSSRHLILTVKDVGRLPHARTTVD-ETKWIASSRIRETMANSAGFLGDLTTEGINKPGFYKGPAGSQVTLSSLGNQTRVLLEEQARHLLNEQEHATMAYYLDEYRGGSVSVEALVMAL 191

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: USH1C (USH1 protein network component harmonin [Source:HGNC Symbol;Acc:HGNC:12597])

HSP 1 Score: 55.0694 bits (131), Expect = 3.742e-7
Identity = 70/271 (25.83%), Postives = 117/271 (43.17%), Query Frame = 1

Query:  502 PLNFASEY-----FNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGV----SSED---IWENVGNDYKWIDCVNDRICHPPLNYTICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTF--KLPMTD--KIQEPRSRSVGR 1266
            PL    EY       SR L   RL RL   H     LS+R  G+E+        ++I++     L K        +Q+G  + +ING   S    EE I+++     + + ++  G+    SS D    W+ V         V   +  P          ++ K + +    S+ +G +I  G     GI+IS +KPGS+ + +G + GD+I+++N V F+  +     EA + L    S  I + +    +L MTD  ++ E R R + R
Sbjct:   67 PLKHQVEYDQLTPRRSRKLKEVRLDRL---HPEGLGLSVR-GGLEF-----GCGLFISH-----LIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPLTWQYVDQFVSESGGVRGSLGSPGNR------ENKEKKVFISLVGSRGLGCSISSGPIQKPGIFISHVKPGSLSAEVGLEIGDQIVEVNGVDFSNLD---HKEAVNVLKSSRSLTISIVAAAGRELFMTDRERLAEARQRELQR 314

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: dysc (gene:FBgn0264006 transcript:FBtr0330418)

HSP 1 Score: 73.9442 bits (180), Expect = 4.304e-13
Identity = 37/93 (39.78%), Postives = 57/93 (61.29%), Query Frame = 1

Query: 2095 VTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNSEKID 2373
            +TV K  P+LGI+IEGG NT HPL RI  +  +  A   G +  G +ILEV+G  + G+ H ++A+ IAE F +     ITFL++++    ++
Sbjct:  887 ITVKKTKPILGIAIEGGANTKHPLPRIINIHENGAAFEAGGLEVGQLILEVDGTKVEGLHHQEVARLIAECFANREKAEITFLVVEAKKSNLE 979

HSP 2 Score: 52.373 bits (124), Expect = 2.124e-6
Identity = 56/217 (25.81%), Postives = 95/217 (43.78%), Query Frame = 1

Query:  880 WIDCVNDRICHPPLNY--TICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPM--TDKIQEP---RSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQD-----VNKILFLLEKYSNTELNVHQLVTAIQ 1494
            W+D  + R   PP+ Y         R++ +ELL +  Q +G+ I GG +Y LGI+++ +   S+    G   GD+IL++N  SF         EA   L       + +    K+P   T    EP    S +  R+RRK  + +++E K             + L +    +L   ++E+++K       V  +L +L+ Y       H LVT I+
Sbjct:  438 WMD-RHGRPASPPMEYGGRRSERRDRIRRVELLIEPGQSLGLMIRGGVEYGLGIFVTGVDKDSVADRSGLMIGDEILEVNGQSFLDV---THDEAVGQLKYHKRMSLVIRDVGKVPHSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEK-----------ARSLLPRHHFASLSYYIAEYSAKAMTIDAFVAVLLEMLDTYEK-----HTLVTEIR 634

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: dysc (gene:FBgn0264006 transcript:FBtr0330414)

HSP 1 Score: 73.9442 bits (180), Expect = 4.633e-13
Identity = 37/93 (39.78%), Postives = 57/93 (61.29%), Query Frame = 1

Query: 2095 VTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNSEKID 2373
            +TV K  P+LGI+IEGG NT HPL RI  +  +  A   G +  G +ILEV+G  + G+ H ++A+ IAE F +     ITFL++++    ++
Sbjct:  887 ITVKKTKPILGIAIEGGANTKHPLPRIINIHENGAAFEAGGLEVGQLILEVDGTKVEGLHHQEVARLIAECFANREKAEITFLVVEAKKSNLE 979

HSP 2 Score: 51.9878 bits (123), Expect = 2.195e-6
Identity = 56/217 (25.81%), Postives = 95/217 (43.78%), Query Frame = 1

Query:  880 WIDCVNDRICHPPLNY--TICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPM--TDKIQEP---RSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQD-----VNKILFLLEKYSNTELNVHQLVTAIQ 1494
            W+D  + R   PP+ Y         R++ +ELL +  Q +G+ I GG +Y LGI+++ +   S+    G   GD+IL++N  SF         EA   L       + +    K+P   T    EP    S +  R+RRK  + +++E K             + L +    +L   ++E+++K       V  +L +L+ Y       H LVT I+
Sbjct:  438 WMD-RHGRPASPPMEYGGRRSERRDRIRRVELLIEPGQSLGLMIRGGVEYGLGIFVTGVDKDSVADRSGLMIGDEILEVNGQSFLDV---THDEAVGQLKYHKRMSLVIRDVGKVPHSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEK-----------ARSLLPRHHFASLSYYIAEYSAKAMTIDAFVAVLLEMLDTYEK-----HTLVTEIR 634

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: dysc (gene:FBgn0264006 transcript:FBtr0330419)

HSP 1 Score: 73.9442 bits (180), Expect = 4.723e-13
Identity = 37/93 (39.78%), Postives = 57/93 (61.29%), Query Frame = 1

Query: 2095 VTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNSEKID 2373
            +TV K  P+LGI+IEGG NT HPL RI  +  +  A   G +  G +ILEV+G  + G+ H ++A+ IAE F +     ITFL++++    ++
Sbjct:  912 ITVKKTKPILGIAIEGGANTKHPLPRIINIHENGAAFEAGGLEVGQLILEVDGTKVEGLHHQEVARLIAECFANREKAEITFLVVEAKKSNLE 1004

HSP 2 Score: 51.9878 bits (123), Expect = 2.305e-6
Identity = 56/217 (25.81%), Postives = 95/217 (43.78%), Query Frame = 1

Query:  880 WIDCVNDRICHPPLNY--TICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPM--TDKIQEP---RSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQD-----VNKILFLLEKYSNTELNVHQLVTAIQ 1494
            W+D  + R   PP+ Y         R++ +ELL +  Q +G+ I GG +Y LGI+++ +   S+    G   GD+IL++N  SF         EA   L       + +    K+P   T    EP    S +  R+RRK  + +++E K             + L +    +L   ++E+++K       V  +L +L+ Y       H LVT I+
Sbjct:  438 WMD-RHGRPASPPMEYGGRRSERRDRIRRVELLIEPGQSLGLMIRGGVEYGLGIFVTGVDKDSVADRSGLMIGDEILEVNGQSFLDV---THDEAVGQLKYHKRMSLVIRDVGKVPHSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEK-----------ARSLLPRHHFASLSYYIAEYSAKAMTIDAFVAVLLEMLDTYEK-----HTLVTEIR 634

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: dysc (gene:FBgn0264006 transcript:FBtr0330417)

HSP 1 Score: 73.559 bits (179), Expect = 4.812e-13
Identity = 37/93 (39.78%), Postives = 57/93 (61.29%), Query Frame = 1

Query: 2095 VTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNSEKID 2373
            +TV K  P+LGI+IEGG NT HPL RI  +  +  A   G +  G +ILEV+G  + G+ H ++A+ IAE F +     ITFL++++    ++
Sbjct:  763 ITVKKTKPILGIAIEGGANTKHPLPRIINIHENGAAFEAGGLEVGQLILEVDGTKVEGLHHQEVARLIAECFANREKAEITFLVVEAKKSNLE 855

HSP 2 Score: 52.373 bits (124), Expect = 1.976e-6
Identity = 56/217 (25.81%), Postives = 95/217 (43.78%), Query Frame = 1

Query:  880 WIDCVNDRICHPPLNY--TICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPM--TDKIQEP---RSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQD-----VNKILFLLEKYSNTELNVHQLVTAIQ 1494
            W+D  + R   PP+ Y         R++ +ELL +  Q +G+ I GG +Y LGI+++ +   S+    G   GD+IL++N  SF         EA   L       + +    K+P   T    EP    S +  R+RRK  + +++E K             + L +    +L   ++E+++K       V  +L +L+ Y       H LVT I+
Sbjct:  438 WMD-RHGRPASPPMEYGGRRSERRDRIRRVELLIEPGQSLGLMIRGGVEYGLGIFVTGVDKDSVADRSGLMIGDEILEVNGQSFLDV---THDEAVGQLKYHKRMSLVIRDVGKVPHSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEK-----------ARSLLPRHHFASLSYYIAEYSAKAMTIDAFVAVLLEMLDTYEK-----HTLVTEIR 634

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: dysc (gene:FBgn0264006 transcript:FBtr0333021)

HSP 1 Score: 73.559 bits (179), Expect = 5.571e-13
Identity = 37/93 (39.78%), Postives = 57/93 (61.29%), Query Frame = 1

Query: 2095 VTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNSEKID 2373
            +TV K  P+LGI+IEGG NT HPL RI  +  +  A   G +  G +ILEV+G  + G+ H ++A+ IAE F +     ITFL++++    ++
Sbjct:  879 ITVKKTKPILGIAIEGGANTKHPLPRIINIHENGAAFEAGGLEVGQLILEVDGTKVEGLHHQEVARLIAECFANREKAEITFLVVEAKKSNLE 971

HSP 2 Score: 54.299 bits (129), Expect = 4.691e-7
Identity = 76/338 (22.49%), Postives = 135/338 (39.94%), Query Frame = 1

Query:  637 STYSIYITNVDDVTLYKRNNIYER-DIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLI------------LQGKGVSSEDIW-----------------------ENVGNDYK----WIDCVNDRICHPPLNY--TICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPM--TDKIQEP---RSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQD-----VNKILFLLEKYSNTELNVHQLVTAIQ 1494
            S   +YI+ +++      N++ ER  ++ G  + ++NG   + +  EE + IL +S  + +             L G G  S D                            G  ++    W+D  + R   PP+ Y         R++ +ELL +  Q +G+ I GG +Y LGI+++ +   S+    G   GD+IL++N  SF         EA   L       + +    K+P   T    EP    S +  R+RRK  + +++E K             + L +    +L   ++E+++K       V  +L +L+ Y       H LVT I+
Sbjct:  319 SGLGVYISRIEE------NSVAERAGLRPGDTILEVNGTPFTSINHEEALKILKSSRQISMTVRAPPTLNSTAPLHGFGPPSRDPMYASMAPPLHPQNQAAAAAAAAAASGAGLPFRQTCSWMD-RHGRPASPPMEYGGRRSERRDRIRRVELLIEPGQSLGLMIRGGVEYGLGIFVTGVDKDSVADRSGLMIGDEILEVNGQSFLDV---THDEAVGQLKYHKRMSLVIRDVGKVPHSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEK-----------ARSLLPRHHFASLSYYIAEYSAKAMTIDAFVAVLLEMLDTYEK-----HTLVTEIR 630

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: whrnb (whirlin b [Source:ZFIN;Acc:ZDB-GENE-060526-377])

HSP 1 Score: 89.7373 bits (221), Expect = 8.345e-18
Identity = 53/153 (34.64%), Postives = 76/153 (49.67%), Query Frame = 1

Query: 1924 QTMKESQNLEKNVDIEDEEIKVISRKTISTPKEYISMQYNIPKEEIIKLAGNKLKK-------LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNS 2361
            Q     Q L ++  ++  E   +S+ +   P +    Q+         LA    K+       LV VPK    LGI++EGG NT  PL RI  +       LCG++  G +ILEVNG+ L GMEH    + IAE+FK+   D + FL+M+ NS
Sbjct:  792 QLSDSGQTLSEDSGVDIAEAGGLSKDSSPRPGKPPFQQFTGDTRRAEGLAQATAKQMGMMEPILVRVPKCASTLGIAVEGGANTRQPLPRIATIQKGGSVHLCGQLRVGQVILEVNGVSLKGMEHRDATRLIAEAFKTKDKDHVDFLIMEFNS 944

HSP 2 Score: 59.6918 bits (143), Expect = 1.343e-8
Identity = 85/393 (21.63%), Postives = 153/393 (38.93%), Query Frame = 1

Query:   76 VSTKVYNIKTAMKSLFTDNENKSISSILNDFKLNRSIQYLVDNIQPYIDTKVKLIFLHCLYEIIPSSHQERYYNYCSSKGL--RFNKFGQXXXXXXXXXXXXQRAY-NCNSYFDCDQIDGEAFDMFETKSSSSFRNDNILTKRKNPLNFASEYFNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHPP-------LNYTICLDHSRL-KPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP 1221
            +S  V  +  A+  L  D E +     LN +   R++  LV  ++  ++T  K   L  L  +IP S Q  +  Y +S+GL  + +    +     +    +  A+   +S     Q D         + +S F      T     L   SE        I ++T   S+       S+R        S     IY++ V+  +  +R  +     ++G ++ ++N     ++   E + +L  S  L + +   G        N  + Y W+D     +  PP       L   +   H+   K + +  D  + +G+ I GG +Y LGIYI+ +  GS     G + GD+IL++N  +F    + C  EA   L       + +    +LP
Sbjct:   24 LSVNVKKLHNALNVLLNDFEREQFIHCLNVYHAKRNVFDLVQTLKVILNTPHKRQLLPMLRLVIPRSDQLLFDQY-TSEGLYLKTDLLAASVKHECSEDLSSTNAHAGASSVHFAPQSDQAGPSHGSLRPASVFSTSAEGTAPALMLEAPSE--------IRQVTLKRSKSHEGLGFSIR------GGSEHGVGIYVSLVEPGSSAEREGL-----RVGDQIMKVNNVVFDRVTHGEAVKVLKGSKKLSMSVCSMGRIPGGYVTN--HVYTWVDPQGRSVSPPPDLVEQHSLGGRLSDLHTNTEKKVNISLDDGRSLGLMIRGGAEYALGIYITGVDRGSAAEYSGLKVGDQILEVNGRNF---RSICHDEAVQILKNSRHMLMTIKDVGRLP 391

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: whrna (whirlin a [Source:ZFIN;Acc:ZDB-GENE-091118-27])

HSP 1 Score: 80.8777 bits (198), Expect = 3.798e-15
Identity = 42/92 (45.65%), Postives = 56/92 (60.87%), Query Frame = 1

Query: 2083 LKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            +  LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG+ L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  845 MSTLVRVAKSASTLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGQVILEVNGVSLRGKEHREAARLIAEAFKTKEKDYIDFLITEFN 936

HSP 2 Score: 72.4034 bits (176), Expect = 1.793e-12
Identity = 109/512 (21.29%), Postives = 202/512 (39.45%), Query Frame = 1

Query:   76 VSTKVYNIKTAMKSLFTDNENKSISSILNDFKLNRSIQYLVDNIQPYIDTKVKLIFLHCLYEIIPSSHQERYYNYCSSKGLRF-NKFGQXXXXXXXXXXXXQRAYNCNSYFDCDQIDGEAF-DMFETKSSSSFRNDNILTKRKNPLNFASEYFNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKG-VSSEDIWENVGNDYKWIDCVNDRICHPP------------------LNYTICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTDKIQEPRSRSVGRSRRKD------------------DMYSVLESKGMFHKG-QRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAI 1491
            +S  V  +  A+  L +D E +     LN +   R++  LV  ++  ++   K   L  L  +IP S Q  +  Y +S+GL   ++    + D + +      +    + F   Q+      D   T S  +     +L +     NF  E        I +      +H +   L   I G     S     IY++ V+  +L ++  +     ++G ++ ++N +   ++   + + +L  S  L + ++  G +    I  +V   Y W+D     +  PP                   ++   L     K + L+ D  + +G+ I GG +Y LGIYI+ +  GS     G + GD+IL++N  SF   + P   EA   L       + V    +LP T  +       VG ++                     D  +   +KG F+KG   +Q+T +SL   S   LE Q     ++ +   + + +++Y +  + V QLV A+
Sbjct:   25 LSANVKKLHNALNLLLSDLEREQFIHCLNVYHSKRNVYDLVQTLKVILNVPSKRQLLPMLRLVIPRSDQLLFDQY-TSEGLYLKSEIHARNGDPDGAQEGANSSPTHGANFPASQVALRGSPDSISTSSDGTATLIPLLGR-----NFLPEPPGEIRQVILK------RHKSNEGLGFSIRG----GSEHGVGIYVSLVEPGSLAEKEGL-----RMGDQIMKVNDKVFDRVTHADAVKVLKGSKKLCMSVRSVGRIPGGYITNHV---YTWVDPQGRSVSPPPDLLAEHRSATLRRSNSQGRSHMQLLQDGDEKKVNLVLDDGRSLGLMIRGGAEYSLGIYITGVDRGSAAECGGIKVGDQILEVNGRSFL--SIP-HDEAVRVLKSSHHLMMTVKDVGRLPHTRTV-------VGETKWIASSQISDSSASSSVTGISLDQGASTSAKGGFYKGVAGSQVTLSSLVNQSRAMLEEQARHLLTEPERQTMGYYIQEYRDGHVGVEQLVMAL 502

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: whrna (whirlin a [Source:ZFIN;Acc:ZDB-GENE-091118-27])

HSP 1 Score: 80.8777 bits (198), Expect = 3.963e-15
Identity = 42/92 (45.65%), Postives = 56/92 (60.87%), Query Frame = 1

Query: 2083 LKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            +  LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG+ L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  830 MSTLVRVAKSASTLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGQVILEVNGVSLRGKEHREAARLIAEAFKTKEKDYIDFLITEFN 921

HSP 2 Score: 73.1738 bits (178), Expect = 9.618e-13
Identity = 109/497 (21.93%), Postives = 200/497 (40.24%), Query Frame = 1

Query:   76 VSTKVYNIKTAMKSLFTDNENKSISSILNDFKLNRSIQYLVDNIQPYIDTKVKLIFLHCLYEIIPSSHQERYYNYCSSKGLRF-NKFGQXXXXXXXXXXXXQRAYNCNSYFDCDQIDGEAF-DMFETKSSSSFRNDNILTKRKNPLNFASEYFNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKG-VSSEDIWENVGNDYKWIDCVNDRICHPP------------------LNYTICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTDKIQEPRSRSVGRSR---RKDDMYSVLESKGMFHKG-QRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAI 1491
            +S  V  +  A+  L +D E +     LN +   R++  LV  ++  ++   K   L  L  +IP S Q  +  Y +S+GL   ++    + D + +      +    + F   Q+      D   T S  +     +L +     NF  E        I +      +H +   L   I G     S     IY++ V+  +L ++  +     ++G ++ ++N +   ++   + + +L  S  L + ++  G +    I  +V   Y W+D     +  PP                   ++   L     K + L+ D  + +G+ I GG +Y LGIYI+ +  GS     G + GD+IL++N  SF   + P   EA   L       + V    +LP T  +       VG ++         S   S G F+KG   +Q+T +SL   S   LE Q     ++ +   + + +++Y +  + V QLV A+
Sbjct:   25 LSANVKKLHNALNLLLSDLEREQFIHCLNVYHSKRNVYDLVQTLKVILNVPSKRQLLPMLRLVIPRSDQLLFDQY-TSEGLYLKSEIHARNGDPDGAQEGANSSPTHGANFPASQVALRGSPDSISTSSDGTATLIPLLGR-----NFLPEPPGEIRQVILK------RHKSNEGLGFSIRG----GSEHGVGIYVSLVEPGSLAEKEGL-----RMGDQIMKVNDKVFDRVTHADAVKVLKGSKKLCMSVRSVGRIPGGYITNHV---YTWVDPQGRSVSPPPDLLAEHRSATLRRSNSQGRSHMQLLQDGDEKKVNLVLDDGRSLGLMIRGGAEYSLGIYITGVDRGSAAECGGIKVGDQILEVNGRSFL--SIP-HDEAVRVLKSSHHLMMTVKDVGRLPHTRTV-------VGETKWIASSQISDSSASSSGGFYKGVAGSQVTLSSLVNQSRAMLEEQARHLLTEPERQTMGYYIQEYRDGHVGVEQLVMAL 487

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: whrnb (whirlin b [Source:ZFIN;Acc:ZDB-GENE-060526-377])

HSP 1 Score: 58.151 bits (139), Expect = 3.750e-8
Identity = 85/393 (21.63%), Postives = 153/393 (38.93%), Query Frame = 1

Query:   76 VSTKVYNIKTAMKSLFTDNENKSISSILNDFKLNRSIQYLVDNIQPYIDTKVKLIFLHCLYEIIPSSHQERYYNYCSSKGL--RFNKFGQXXXXXXXXXXXXQRAY-NCNSYFDCDQIDGEAFDMFETKSSSSFRNDNILTKRKNPLNFASEYFNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHPP-------LNYTICLDHSRL-KPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP 1221
            +S  V  +  A+  L  D E +     LN +   R++  LV  ++  ++T  K   L  L  +IP S Q  +  Y +S+GL  + +    +     +    +  A+   +S     Q D         + +S F      T     L   SE        I ++T   S+       S+R        S     IY++ V+  +  +R  +     ++G ++ ++N     ++   E + +L  S  L + +   G        N  + Y W+D     +  PP       L   +   H+   K + +  D  + +G+ I GG +Y LGIYI+ +  GS     G + GD+IL++N  +F    + C  EA   L       + +    +LP
Sbjct:   24 LSVNVKKLHNALNVLLNDFEREQFIHCLNVYHAKRNVFDLVQTLKVILNTPHKRQLLPMLRLVIPRSDQLLFDQY-TSEGLYLKTDLLAASVKHECSEDLSSTNAHAGASSVHFAPQSDQAGPSHGSLRPASVFSTSAEGTAPALMLEAPSE--------IRQVTLKRSKSHEGLGFSIR------GGSEHGVGIYVSLVEPGSSAEREGL-----RVGDQIMKVNNVVFDRVTHGEAVKVLKGSKKLSMSVCSMGRIPGGYVTN--HVYTWVDPQGRSVSPPPDLVEQHSLGGRLSDLHTNTEKKVNISLDDGRSLGLMIRGGAEYALGIYITGVDRGSAAEYSGLKVGDQILEVNGRNF---RSICHDEAVQILKNSRHMLMTIKDVGRLP 391

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: pdzd7a (PDZ domain containing 7a [Source:ZFIN;Acc:ZDB-GENE-090313-191])

HSP 1 Score: 55.4546 bits (132), Expect = 2.683e-7
Identity = 41/164 (25.00%), Postives = 75/164 (45.73%), Query Frame = 1

Query:  646 SIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHPPLNYTICLDHS--RLKPIELLKDVSQE--IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSF 1125
             I+++ V+D +  +   +      +G +L ++NG     +     + +L  +  L ++++  G      +        W+D ++ R+       T     S   L+ I  L   S +  +G NI GGK++ LGIY+S + PG +    G + GD+IL  N VSF
Sbjct:   95 GIFVSKVEDDSTAEMAGLC-----VGDKLVEVNGISLESITMSSAVKVLTGNNRLRMVVRRVGKVPGIRYSK--EKTTWVDLIHRRMVVEESGRTPSEASSDGALRRIVHLYTTSDDYCLGFNIRGGKEFGLGIYVSKLDPGGLAEQNGIKMGDQILAANGVSF 251

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
Match: WHRN (whirlin [Source:NCBI gene;Acc:100486736])

HSP 1 Score: 76.2554 bits (186), Expect = 1.415e-13
Identity = 40/89 (44.94%), Postives = 53/89 (59.55%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            LV V K  P LGI+IEGG  T  PL RI  +     A  C ++  G +ILEVNGI + G EH + A+ IAE+FK+   D + FL+ + N
Sbjct:  756 LVRVKKTAPSLGIAIEGGAKTRQPLPRIVTIQRGGSAHNCSKLKVGQVILEVNGISMQGKEHREAARIIAEAFKTKEKDYMDFLVTEFN 844

HSP 2 Score: 60.077 bits (144), Expect = 1.412e-8
Identity = 48/190 (25.26%), Postives = 81/190 (42.63%), Query Frame = 1

Query:  610 WGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDL-ILQGKGVSSEDIWENVGNDYKWIDCVNDRICHP--------PL---------NYTICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSF 1125
            + I     H T  IY++ V+  +L +     +  +++G ++ + NGR   ++   E +  L  S  L L +L    +    I  ++   Y W+D     +  P        PL         ++   L     K + L+      +G+ I GG +Y LGIYI+ +  GS     G + GD+IL IN  SF
Sbjct:  144 FSIRGGVEHGT-GIYVSLVEPGSLAE-----QEGLRVGDQILKANGRPLDRVTHAEAVKALRGSQKLVLSVLSSGRIPGGHISSHI---YTWVDAHGRSVSPPRGPPHLQSPLLAGTEQEKRSHLQLLQEGDEKKVNLVLGEGSSLGLLIRGGAEYSLGIYITGVDKGSEAESAGLKVGDQILDINGSSF 324

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000028683.1 (lin-7 homolog B [Source:NCBI gene;Acc:100491827])

HSP 1 Score: 50.0618 bits (118), Expect = 3.617e-6
Identity = 39/126 (30.95%), Postives = 62/126 (49.21%), Query Frame = 1

Query:  943 HSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSM-IGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKL--PMTDKIQEPRSRSVGRSRRKDDMYSVLESKG 1311
            H+  + +EL K   + +G NI GGK+    IYIS I PG +     G + GD++L +N VS  G       E   A     +  + V  T K+   M  + ++ R+    R R++ + Y+ LES+G
Sbjct:   88 HAHPRVVELPK-TDEGLGFNIMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQ--GTVKLVVRYTPKVLEEMEARFEKMRT---ARRRQQQNSYTSLESRG 207

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Whrn (whirlin [Source:MGI Symbol;Acc:MGI:2682003])

HSP 1 Score: 75.8702 bits (185), Expect = 8.619e-14
Identity = 42/89 (47.19%), Postives = 54/89 (60.67%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG  L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  385 LVRVRKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGQTLRGKEHKEAARIIAEAFKTKERDYIDFLVTEFN 473

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Whrn (whirlin [Source:MGI Symbol;Acc:MGI:2682003])

HSP 1 Score: 75.485 bits (184), Expect = 9.420e-14
Identity = 42/89 (47.19%), Postives = 54/89 (60.67%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG  L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  374 LVRVRKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGQTLRGKEHKEAARIIAEAFKTKERDYIDFLVTEFN 462

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Whrn (whirlin [Source:MGI Symbol;Acc:MGI:2682003])

HSP 1 Score: 76.2554 bits (186), Expect = 1.210e-13
Identity = 42/89 (47.19%), Postives = 54/89 (60.67%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG  L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  827 LVRVRKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGQTLRGKEHKEAARIIAEAFKTKERDYIDFLVTEFN 915

HSP 2 Score: 66.2402 bits (160), Expect = 1.431e-10
Identity = 71/312 (22.76%), Postives = 127/312 (40.71%), Query Frame = 1

Query:  646 SIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHP-----PLNYTI------------CLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP------------MTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQR-NQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAI 1491
             IY++ V+  +L ++  +     ++G ++ ++N +  +++   E +  L  S  L L +   G        N  + Y W+D        P     P   T+             L     K + L+    + +G+ I GG +Y LGIYI+ + PGS     G + GD+IL++N  SF         EA   L       + V    +LP             + +I E  + S G      D      SK  F+KG   +Q+T +SL   +   L+ Q     ++Q+   +++ L +Y    ++V  +V A+
Sbjct:  166 GIYVSLVEPGSLAEKEGL-----RVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTN--HIYTWVDPQGRSTSPPSSLPQPHGSTLRQREDDRRSTLHLLQSGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAESSGLKVGDQILEVNGRSFLNI---LHDEAVKLLKSSRHLILTVKDVGRLPHARTTVDQTKWIASSRIGESVANSAG---FPGDHTEEGTSKPGFYKGPAGSQVTLSSLGNQTRALLDDQARHLLTEQERATMMYYLAQYRGGTISVEAMVMAL 464

HSP 3 Score: 53.5286 bits (127), Expect = 1.167e-6
Identity = 27/77 (35.06%), Postives = 43/77 (55.84%), Query Frame = 1

Query:  991 IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP 1221
            +G +I GG ++ +GIY+S ++PGS+    G + GD+IL++N  S         AEA  AL       + VYS  ++P
Sbjct:  153 LGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLA---RVTHAEAVKALKGSKKLVLSVYSAGRIP 226

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Whrn (whirlin [Source:MGI Symbol;Acc:MGI:2682003])

HSP 1 Score: 76.2554 bits (186), Expect = 1.324e-13
Identity = 42/89 (47.19%), Postives = 54/89 (60.67%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG  L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  820 LVRVRKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGQTLRGKEHKEAARIIAEAFKTKERDYIDFLVTEFN 908

HSP 2 Score: 68.9366 bits (167), Expect = 2.018e-11
Identity = 72/313 (23.00%), Postives = 128/313 (40.89%), Query Frame = 1

Query:  646 SIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHP-----PLNYTI------------CLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP------------MTDKIQEPRSRSVGRSRR-KDDMYSVLESKGMFHKGQR-NQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAI 1491
             IY++ V+  +L ++  +     ++G ++ ++N +  +++   E +  L  S  L L +   G        N  + Y W+D        P     P   T+             L     K + L+    + +G+ I GG +Y LGIYI+ + PGS     G + GD+IL++N  SF         EA   L       + V    +LP             + +I E  + S G   R   D      SK  F+KG   +Q+T +SL   +   L+ Q     ++Q+   +++ L +Y    ++V  +V A+
Sbjct:  166 GIYVSLVEPGSLAEKEGL-----RVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTN--HIYTWVDPQGRSTSPPSSLPQPHGSTLRQREDDRRSTLHLLQSGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAESSGLKVGDQILEVNGRSFLNI---LHDEAVKLLKSSRHLILTVKDVGRLPHARTTVDQTKWIASSRIGESVANSAGSGLRFPGDHTEEGTSKPGFYKGPAGSQVTLSSLGNQTRALLDDQARHLLTEQERATMMYYLAQYRGGTISVEAMVMAL 468

HSP 3 Score: 53.5286 bits (127), Expect = 1.226e-6
Identity = 27/77 (35.06%), Postives = 43/77 (55.84%), Query Frame = 1

Query:  991 IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP 1221
            +G +I GG ++ +GIY+S ++PGS+    G + GD+IL++N  S         AEA  AL       + VYS  ++P
Sbjct:  153 LGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLA---RVTHAEAVKALKGSKKLVLSVYSAGRIP 226

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Whrn (whirlin [Source:MGI Symbol;Acc:MGI:2682003])

HSP 1 Score: 75.8702 bits (185), Expect = 1.354e-13
Identity = 42/89 (47.19%), Postives = 54/89 (60.67%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG  L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  815 LVRVRKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGQTLRGKEHKEAARIIAEAFKTKERDYIDFLVTEFN 903

HSP 2 Score: 66.2402 bits (160), Expect = 1.524e-10
Identity = 71/312 (22.76%), Postives = 127/312 (40.71%), Query Frame = 1

Query:  646 SIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHP-----PLNYTI------------CLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP------------MTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQR-NQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAI 1491
             IY++ V+  +L ++  +     ++G ++ ++N +  +++   E +  L  S  L L +   G        N  + Y W+D        P     P   T+             L     K + L+    + +G+ I GG +Y LGIYI+ + PGS     G + GD+IL++N  SF         EA   L       + V    +LP             + +I E  + S G      D      SK  F+KG   +Q+T +SL   +   L+ Q     ++Q+   +++ L +Y    ++V  +V A+
Sbjct:  166 GIYVSLVEPGSLAEKEGL-----RVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTN--HIYTWVDPQGRSTSPPSSLPQPHGSTLRQREDDRRSTLHLLQSGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAESSGLKVGDQILEVNGRSFLNI---LHDEAVKLLKSSRHLILTVKDVGRLPHARTTVDQTKWIASSRIGESVANSAG---FPGDHTEEGTSKPGFYKGPAGSQVTLSSLGNQTRALLDDQARHLLTEQERATMMYYLAQYRGGTISVEAMVMAL 464

HSP 3 Score: 53.5286 bits (127), Expect = 1.255e-6
Identity = 27/77 (35.06%), Postives = 43/77 (55.84%), Query Frame = 1

Query:  991 IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP 1221
            +G +I GG ++ +GIY+S ++PGS+    G + GD+IL++N  S         AEA  AL       + VYS  ++P
Sbjct:  153 LGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLA---RVTHAEAVKALKGSKKLVLSVYSAGRIP 226

[Close]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9P202|WHRN_HUMAN (Whirlin OS=Homo sapiens OX=9606 GN=WHRN PE=1 SV=4)

HSP 1 Score: 79.337 bits (194), Expect = 7.992e-14
Identity = 58/179 (32.40%), Postives = 85/179 (47.49%), Query Frame = 1

Query: 1843 FDEIRKINKDNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISRKTISTPKEYISMQYNIPKEEIIKLAGNK-------LKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
             +E+R + +      L +    + +  QT+ E    +  VD  + E     R   S   +  S +  +P+ E      NK          LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG+ L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  735 VNEVRALPQTRTASTLSQ----LSDSGQTLSE----DSGVDAGEAEASAPGRGRQSVSTKSRSSK-ELPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFN 904

HSP 2 Score: 65.855 bits (159), Expect = 1.332e-9
Identity = 77/340 (22.65%), Postives = 143/340 (42.06%), Query Frame = 1

Query:  646 SIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHP---PLNYTICL---DHSRLKPIELLKDVSQE-----------IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP------------MTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQR-NQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNTLRVNDRMTF 1575
             IY++ V+  +L ++  +     ++G ++ ++N +  +++   E +  L  S  L L +   G        N  + Y W+D     I  P   P  +   L   +  R   + LL+   ++           +G+ I GG +Y LGIYI+ + PGS     G + GD+IL++N  SF         EA   L       + V    +LP             + +I+E  + S G      D+ +   +K  F+KG   +Q+T +SL   +   LE Q     ++Q+   + + L++Y    ++V  LV A+   ++      L++ +  T+   D   F
Sbjct:  165 GIYVSLVEPGSLAEKEGL-----RVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTN--HIYTWVDPQGRSISPPSGLPQPHGGALRQQEGDRRSTLHLLQGGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAEGSGLKVGDQILEVNGRSFLNI---LHDEAVRLLKSSRHLILTVKDVGRLPHARTTVDETKWIASSRIRETMANSAG---FLGDLTTEGINKPGFYKGPAGSQVTLSSLGNQTRVLLEEQARHLLNEQEHATMAYYLDEYRGGSVSVEALVMALFKLLNTHAKFSLLSEVRGTISPQDLERF 491

HSP 3 Score: 53.9138 bits (128), Expect = 6.920e-6
Identity = 32/96 (33.33%), Postives = 53/96 (55.21%), Query Frame = 1

Query:  991 IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP---MTDKIQ---EPRSRSV 1260
            +G +I GG ++ +GIY+S ++PGS+    G + GD+IL++N  S         AEA  AL       + VYS  ++P   +T+ I    +P+ RS+
Sbjct:  152 LGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLA---RVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTNHIYTWVDPQGRSI 244

[Close]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|Q80VW5|WHRN_MOUSE (Whirlin OS=Mus musculus OX=10090 GN=Whrn PE=1 SV=3)

HSP 1 Score: 76.2554 bits (186), Expect = 8.462e-13
Identity = 42/89 (47.19%), Postives = 54/89 (60.67%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            LV V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG  L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  827 LVRVRKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGQTLRGKEHKEAARIIAEAFKTKERDYIDFLVTEFN 915

HSP 2 Score: 66.2402 bits (160), Expect = 1.001e-9
Identity = 71/312 (22.76%), Postives = 127/312 (40.71%), Query Frame = 1

Query:  646 SIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHP-----PLNYTI------------CLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP------------MTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQR-NQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAI 1491
             IY++ V+  +L ++  +     ++G ++ ++N +  +++   E +  L  S  L L +   G        N  + Y W+D        P     P   T+             L     K + L+    + +G+ I GG +Y LGIYI+ + PGS     G + GD+IL++N  SF         EA   L       + V    +LP             + +I E  + S G      D      SK  F+KG   +Q+T +SL   +   L+ Q     ++Q+   +++ L +Y    ++V  +V A+
Sbjct:  166 GIYVSLVEPGSLAEKEGL-----RVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTN--HIYTWVDPQGRSTSPPSSLPQPHGSTLRQREDDRRSTLHLLQSGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAESSGLKVGDQILEVNGRSFLNI---LHDEAVKLLKSSRHLILTVKDVGRLPHARTTVDQTKWIASSRIGESVANSAG---FPGDHTEEGTSKPGFYKGPAGSQVTLSSLGNQTRALLDDQARHLLTEQERATMMYYLAQYRGGTISVEAMVMAL 464

[Close]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|Q810W9|WHRN_RAT (Whirlin OS=Rattus norvegicus OX=10116 GN=Whrn PE=1 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 1.086e-12
Identity = 41/89 (46.07%), Postives = 54/89 (60.67%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            L+ V K+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG  L G EH + A+ IAE+FK+   D I FL+ + N
Sbjct:  829 LIRVRKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGQTLRGKEHREAARVIAEAFKTKERDYIDFLVTEFN 917

HSP 2 Score: 68.5514 bits (166), Expect = 2.154e-10
Identity = 71/310 (22.90%), Postives = 129/310 (41.61%), Query Frame = 1

Query:  646 SIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHP---PLNYTI------------CLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP------------MTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQRN-QLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAI 1491
             IY++ V+  +L ++  +     ++G ++ ++N +  +++   E +  L  S  L L +   G        N  + Y W+D        P   P   T+             L     K + L+    + +G+ I GG +Y LGIYI+ + PGS     G + GD+IL++N  SF    +    EA   L       + V    +LP             + +I E  + S G      D+     +K  F+KG    Q+T +SL   +   L+ Q     ++Q+   +++ L++Y    ++V  LV A+
Sbjct:  166 GIYVSLVEPGSLAEKEGL-----RVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTN--HIYTWVDPQGRSTSPPSSLPHGSTLRQHEDDRRSALHLLQSGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAESSGLKVGDQILEVNGRSFL---SILHDEAVKLLKSSRHLILTVKDVGRLPHARTTVDQTKWIASSRIGESITNSAG---FPGDLTEEGTNKPGFYKGPAGSQVTLSSLGNQTRALLDDQARHLLTEQERATMMYYLDQYRGGTISVEALVMAL 462

[Close]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9ES64|USH1C_MOUSE (Harmonin OS=Mus musculus OX=10090 GN=Ush1c PE=1 SV=1)

HSP 1 Score: 56.225 bits (134), Expect = 1.259e-6
Identity = 71/271 (26.20%), Postives = 121/271 (44.65%), Query Frame = 1

Query:  502 PLNFASEY-----FNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGV-----SSEDI--WENVGNDYKWIDCVNDRICHPPLNYTICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTF--KLPMTD--KIQEPRSRSVGR 1266
            PL    EY       SR L   RL RL   H     LS+R  G+E+        ++I++     L K        +Q+G  + +ING   S    EE I+++     + + ++  G+     S E+   W+ V         V   +  P  N T     ++ K + +    S+ +G +I  G     GI++S +KPGS+ + +G +TGD+I+++N + FT  +     EA + L    S  I + +    +L MTD  +++E R R + R
Sbjct:   67 PLKHQVEYDQLTPRRSRKLKEVRLDRL---HPEGLGLSVR-GGLEF-----GCGLFISH-----LIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPEESLKWQYVDQFVSESGGVRGGLGSP-GNRT-----TKEKKVFISLVGSRGLGCSISSGPIQKPGIFVSHVKPGSLSAEVGLETGDQIVEVNGIDFTNLD---HKEAVNVLKSSRSLTISIVAGAGRELFMTDRERLEEARQRELQR 314

[Close]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9Z252|LIN7B_RAT (Protein lin-7 homolog B OS=Rattus norvegicus OX=10116 GN=Lin7b PE=1 SV=1)

HSP 1 Score: 52.7582 bits (125), Expect = 2.727e-6
Identity = 41/132 (31.06%), Postives = 64/132 (48.48%), Query Frame = 1

Query:  925 YTICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSM-IGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKL--PMTDKIQEPRSRSVGRSRRKDDMYSVLESKG 1311
            +T    H+  + +EL K   + +G NI GGK+    IYIS + PG +     G + GD++L +N VS  G +     E   A     S  + V  T ++   M  + ++ RS    R R++   YS LES+G
Sbjct:   82 FTASEGHAHPRVVELPK-TDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQ--GSVKLVVRYTPRVLEEMEARFEKMRS---ARRRQQHHSYSSLESRG 207

[Close]

BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A5E4NAN0 (Uncharacterized protein OS=Cinara cedri OX=506608 GN=CINCED_3A004566 PE=4 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 3.371e-22
Identity = 137/619 (22.13%), Postives = 249/619 (40.23%), Query Frame = 1

Query:  637 STYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQ----------------GKGVSSEDIWENVGNDYKWIDCVNDRICHPPLNYTICLD-----------HSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNTLRVNDR-----MTFKMKLEVIQALREEKASITTSRSAHQTPIFQRPNLTENVGENDEISVIRRPIFKKPEFSHQN---SSNSEKDLPFK--EQTMESLDCEFQEKPSLFDEIRKINK---DNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISRKTISTPKEYISMQYNIPKEEIIKLAGNKLKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNSEKID 2373
            S   +YI+ V++ ++ +        ++ G  + ++NGR  S +  EE + I  +   + + ++                 +  + +D W  +   Y WI+     +  PPL Y   +              +++ +ELL +  Q +G+ I GG +Y LGI+I+ I   S+    G   GD+IL++N  SF         EA + L       + V    K+P +     P S +          +S+  + G    G          T  +   +E +     +K + N + + L++YS + +++   +T +   ++      L+  +   +  +DR     + ++   E  +    +  +  ++    Q+  F  PN  EN G +              E+S+ N   S N  KD P K  +Q+    D E +E      ++   +    D K E+L+E  N  +E       S NL+ +  I                   +  Q N+                + V K  P+LGI+IEGGINT H L RI  +  +  A   G +  G +ILEV+G  + GM H ++A+ IAESF       I FL++++    ++
Sbjct:  226 SNVGVYISRVEEGSIAE-----SVGLKPGDSILEVNGRPFSSISHEEALKIFKSYRQITMTVKCPSPPQSMPTMHKKDDDENTNQDDSWR-LTRTYSWINRKGQPVS-PPLEYAKPISPYSKWSYTRSSKDKIRKVELLIEPGQSLGLMIRGGTEYNLGIFITGIDKDSVADRSGLMIGDQILEVNGQSFL---NLSHDEAVNQLKFQKQMTLTVRDVGKVPHSCTTYNPESWN----------HSIDNADGALKLG----------TSAASQMVEEKARILLTKNEFNTLRYYLDEYSCSRMSIDAFITILFELLNTTDKFTLLTELRELIGPSDRDRFDQLVYRRGRESRKTHSRKLDNFNSNIPGGQSKGFDFPN--ENSGMD----------IGTTEYSNSNYRTSGNKGKDSPMKTNDQSQSHRDMEVEEFEYSHQQLSNKHGRSYDGKNELLDEDGNYRRESGFIESSSSNLQNDSQI------------------MLDQQGNL---------------RIIVKKIKPLLGIAIEGGINTKHLLPRIINIHENGAAYEAGGLEVGQLILEVDGQKVEGMPHQEVARLIAESFAQTDKSEIEFLVVEAKKSNLE 769

[Close]

BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A5E4NGN3 (Uncharacterized protein OS=Cinara cedri OX=506608 GN=CINCED_3A004566 PE=4 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 1.406e-20
Identity = 140/643 (21.77%), Postives = 255/643 (39.66%), Query Frame = 1

Query:  637 STYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQ----------------GKGVSSEDIWENVGNDYKWIDCVNDRICHPPLNYTICLD-----------HSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNTLRVNDR-----MTFKMKLEVIQALREEKASITTSRSAHQTPIFQRPNLTENVG--------------------------ENDEISVIRRPIFKKPEFSHQNSSNSEKDLPFKEQTMESLDCEFQEKPS-LFDEIRKI------NK-----DNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISRKTISTPKEYISMQYNIPKEEIIKLAGNKLKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKS 2355
            S   +YI+ V++ ++ +        ++ G  + ++NGR  S +  EE + I  +   + + ++                 +  + +D W  +   Y WI+     +  PPL Y   +              +++ +ELL +  Q +G+ I GG +Y LGI+I+ I   S+    G   GD+IL++N  SF         EA + L       + V    K+P +     P S +          +S+  + G    G          T  +   +E +     +K + N + + L++YS + +++   +T +   ++      L+  +   +  +DR     + ++   E  +    +  +  ++    Q+  F  PN  EN G                           ND+    R    ++ E+SHQ+  + E +L  ++   + +D  +  + S L+DE          NK     D K E+L+E  N  +E       S NL+ +  I                   +  Q N+                + V K  P+LGI+IEGGINT H L RI  +  +  A   G +  G +ILEV+G  + GM H ++A+ IAESF       I FL++++
Sbjct:  226 SNVGVYISRVEEGSIAE-----SVGLKPGDSILEVNGRPFSSISHEEALKIFKSYRQITMTVKCPSPPQSMPTMHKKDDDENTNQDDSWR-LTRTYSWINRKGQPVS-PPLEYAKPISPYSKWSYTRSSKDKIRKVELLIEPGQSLGLMIRGGTEYNLGIFITGIDKDSVADRSGLMIGDQILEVNGQSFL---NLSHDEAVNQLKFQKQMTLTVRDVGKVPHSCTTYNPESWN----------HSIDNADGALKLG----------TSAASQMVEEKARILLTKNEFNTLRYYLDEYSCSRMSIDAFITILFELLNTTDKFTLLTELRELIGPSDRDRFDQLVYRRGRESRKTHSRKLDNFNSNIPGGQSKGFDFPN--ENSGMDIGTTEYSNSNYRTSGNKGKDSPMKTNDQSQSHRDMEVEEFEYSHQDYGDLETELLPRKYHNDLIDVGYTHRNSGLYDESNMTRSSQLSNKHGRSYDGKNELLDEDGNYRRESGFIESSSSNLQNDSQI------------------MLDQQGNL---------------RIIVKKIKPLLGIAIEGGINTKHLLPRIINIHENGAAYEAGGLEVGQLILEVDGQKVEGMPHQEVARLIAESFAQTDKSEIEFLVVEA 803

[Close]

BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A5E4ND79 (PDZ domain OS=Cinara cedri OX=506608 GN=CINCED_3A004566 PE=4 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 1.495e-20
Identity = 140/649 (21.57%), Postives = 258/649 (39.75%), Query Frame = 1

Query:  637 STYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQ----------------GKGVSSEDIWENVGNDYKWIDCVNDRICHPPLNYTICLD-----------HSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNTLRVNDR-----MTFKMKLEVIQALREEKASITTSRSAHQTPIFQRPNLTENVG--------------------------ENDEISVIRRPIFKKPEFSHQNSSNSEKDLPFKEQTMESLDCEFQEKPS-LFDEIRKI------NK-----DNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISRKTISTPKEYISMQYNIPKEEIIKLAGNKLKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNSEKID 2373
            S   +YI+ V++ ++ +        ++ G  + ++NGR  S +  EE + I  +   + + ++                 +  + +D W  +   Y WI+     +  PPL Y   +              +++ +ELL +  Q +G+ I GG +Y LGI+I+ I   S+    G   GD+IL++N  SF   +     EA + L       + V    K+P +     P S +          +S+  + G    G          T  +   +E +     +K + N + + L++YS + +++   +T +   ++      L+  +   +  +DR     + ++   E  +    +  +  ++    Q+  F  PN  EN G                           ND+    R    ++ E+SHQ+  + E +L  ++   + +D  +  + S L+DE          NK     D K E+L+E  N  +E       S NL+ +  I                   +  Q N+                + V K  P+LGI+IEGGINT H L RI  +  +  A   G +  G +ILEV+G  + GM H ++A+ IAESF       I FL++++    ++
Sbjct:  443 SNVGVYISRVEEGSIAE-----SVGLKPGDSILEVNGRPFSSISHEEALKIFKSYRQITMTVKCPSPPQSMPTMHKKDDDENTNQDDSWR-LTRTYSWINRKGQPVS-PPLEYAKPISPYSKWSYTRSSKDKIRKVELLIEPGQSLGLMIRGGTEYNLGIFITGIDKDSVADRSGLMIGDQILEVNGQSFLNLS---HDEAVNQLKFQKQMTLTVRDVGKVPHSCTTYNPESWN----------HSIDNADGALKLG----------TSAASQMVEEKARILLTKNEFNTLRYYLDEYSCSRMSIDAFITILFELLNTTDKFTLLTELRELIGPSDRDRFDQLVYRRGRESRKTHSRKLDNFNSNIPGGQSKGFDFPN--ENSGMDIGTTEYSNSNYRTSGNKGKDSPMKTNDQSQSHRDMEVEEFEYSHQDYGDLETELLPRKYHNDLIDVGYTHRNSGLYDESNMTRSSQLSNKHGRSYDGKNELLDEDGNYRRESGFIESSSSNLQNDSQI------------------MLDQQGNL---------------RIIVKKIKPLLGIAIEGGINTKHLLPRIINIHENGAAYEAGGLEVGQLILEVDGQKVEGMPHQEVARLIAESFAQTDKSEIEFLVVEAKKSNLE 1026

[Close]

BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A5E4NAA2 (Uncharacterized protein OS=Cinara cedri OX=506608 GN=CINCED_3A004566 PE=4 SV=1)

HSP 1 Score: 107.842 bits (268), Expect = 3.541e-20
Identity = 139/646 (21.52%), Postives = 251/646 (38.85%), Query Frame = 1

Query:  637 STYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQ----------------GKGVSSEDIWENVGNDYKWIDCVNDRICHPPLNYTICLD-----------HSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNTLRVNDR-----MTFKMKLEVIQALREEKASITTSRSAHQTPIFQRPNLTENVGENDEISVIRRPIFKKPEFSHQN---SSNSEKDLPFK-------EQTMESLDCEFQEKPSLFDEIRK--------------------INK-----DNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISRKTISTPKEYISMQYNIPKEEIIKLAGNKLKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNSEKID 2373
            S   +YI+ V++ ++ +        ++ G  + ++NGR  S +  EE + I  +   + + ++                 +  + +D W  +   Y WI+     +  PPL Y   +              +++ +ELL +  Q +G+ I GG +Y LGI+I+ I   S+    G   GD+IL++N  SF         EA + L       + V    K+P +     P S +          +S+  + G    G          T  +   +E +     +K + N + + L++YS + +++   +T +   ++      L+  +   +  +DR     + ++   E  +    +  +  ++    Q+  F  PN  EN G +              E+S+ N   S N  KD P K        + ME  + E+  +    + +R                      NK     D K E+L+E  N  +E       S NL+ +  I                   +  Q N+                + V K  P+LGI+IEGGINT H L RI  +  +  A   G +  G +ILEV+G  + GM H ++A+ IAESF       I FL++++    ++
Sbjct:  226 SNVGVYISRVEEGSIAE-----SVGLKPGDSILEVNGRPFSSISHEEALKIFKSYRQITMTVKCPSPPQSMPTMHKKDDDENTNQDDSWR-LTRTYSWINRKGQPVS-PPLEYAKPISPYSKWSYTRSSKDKIRKVELLIEPGQSLGLMIRGGTEYNLGIFITGIDKDSVADRSGLMIGDQILEVNGQSFL---NLSHDEAVNQLKFQKQMTLTVRDVGKVPHSCTTYNPESWN----------HSIDNADGALKLG----------TSAASQMVEEKARILLTKNEFNTLRYYLDEYSCSRMSIDAFITILFELLNTTDKFTLLTELRELIGPSDRDRFDQLVYRRGRESRKTHSRKLDNFNSNIPGGQSKGFDFPN--ENSGMD----------IGTTEYSNSNYRTSGNKGKDSPMKTNDQSQSHRDMEVEEFEYSHQSGYLEGLRSHLGGWTQKLKSWYYGSSLQLSNKHGRSYDGKNELLDEDGNYRRESGFIESSSSNLQNDSQI------------------MLDQQGNL---------------RIIVKKIKPLLGIAIEGGINTKHLLPRIINIHENGAAYEAGGLEVGQLILEVDGQKVEGMPHQEVARLIAESFAQTDKSEIEFLVVEAKKSNLE 796

[Close]

BLAST of PDZ domain-containing protein vs. TrEMBL
Match: C3ZWT6 (PDZ domain-containing protein (Fragment) OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_241698 PE=4 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.270e-15
Identity = 40/85 (47.06%), Postives = 54/85 (63.53%), Query Frame = 1

Query: 2095 VTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLM 2349
            VTVPK  P LGI+IEGG NT  PL RI  + P   A   G +  G +ILEV+G  L G+EH   A+ IA++F++ + D + FL+M
Sbjct:    1 VTVPKVAPTLGIAIEGGANTRQPLPRIITIQPGGSADQSGALQVGHVILEVDGKSLQGLEHKDAARAIAQAFRTPAKDYVQFLVM 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: whrna (whirlin [Source:NCBI gene;Acc:103029719])

HSP 1 Score: 84.3445 bits (207), Expect = 2.665e-16
Identity = 43/89 (48.31%), Postives = 56/89 (62.92%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            LV VPK+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNGI L G EH + A+ IAE+FK+   D + FL+ + N
Sbjct:  786 LVRVPKSSSTLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGQVILEVNGISLRGREHREAARLIAEAFKTKEKDHVDFLITEFN 874

HSP 2 Score: 63.5438 bits (153), Expect = 7.728e-10
Identity = 75/338 (22.19%), Postives = 142/338 (42.01%), Query Frame = 1

Query:  574 QHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHPP-----LNYTICLDHSRL------------KPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTDKIQEPRSRSVGRSR-----RKDDMYSVLESKGM---------FHKG-QRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAI 1491
            +H ++  L   I G     S     IY++ V+  +L ++  +     ++G ++ ++N +    +   E + +L  +  L + ++  G        N  + Y W+D     +  PP      + T+  + S+             K + L+ D  + +G+ I GG +Y LGIYI+ +   S     G + GD+IL++N  SF   + P   EA   L       + V    +LP    +       VG ++     +  D   +L S G+         F+KG   +Q+T +SL   S   LE Q     ++ +   + + +++Y +  + V QLV A+
Sbjct:  138 RHKSQEGLGFSIRG----GSEHGVGIYVSLVEPGSLAEKEGL-----RVGDQILKVNDKVFDAVTHAEAVKVLKGNKKLSMSVRSVGRIPGGYVTN--HVYTWVDPQGRSVSPPPDLMEHRSATLRRNESQRRSNMQLLQEGDEKKVNLVLDDGRSLGLMIRGGAEYALGIYITGVDRSSAAECGGLKVGDQILEVNGRSFL--SIP-HDEAVRVLKSSRHLMMTVKDVGRLPHARTV-------VGETKWIASSQITDSSLLLGSAGVKNTYTDEAGFYKGVAGSQVTLSSLVNQSRAMLEEQARHLLTEPERQTMNYYIQEYRDGHIGVEQLVMAL 454

HSP 3 Score: 52.373 bits (124), Expect = 2.194e-6
Identity = 34/107 (31.78%), Postives = 58/107 (54.21%), Query Frame = 1

Query:  961 IELLKDVSQE-IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP---MTDKIQ---EPRSRSV 1260
            + L +  SQE +G +I GG ++ +GIY+S ++PGS+    G + GD+IL++N   F   +    AEA   L       + V S  ++P   +T+ +    +P+ RSV
Sbjct:  134 VTLKRHKSQEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILKVNDKVF---DAVTHAEAVKVLKGNKKLSMSVRSVGRIPGGYVTNHVYTWVDPQGRSV 237

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: whrna (whirlin [Source:NCBI gene;Acc:103029719])

HSP 1 Score: 83.9593 bits (206), Expect = 3.687e-16
Identity = 43/89 (48.31%), Postives = 56/89 (62.92%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            LV VPK+   LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNGI L G EH + A+ IAE+FK+   D + FL+ + N
Sbjct:  847 LVRVPKSSSTLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGQVILEVNGISLRGREHREAARLIAEAFKTKEKDHVDFLITEFN 935

HSP 2 Score: 61.6178 bits (148), Expect = 3.027e-9
Identity = 73/342 (21.35%), Postives = 138/342 (40.35%), Query Frame = 1

Query:  574 QHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHPP-----LNYTICLDHSRL------------KPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTDKIQEPRSRSVGRSR------------------RKDDMYSVLESKGMFHKG-QRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAI 1491
            +H ++  L   I G     S     IY++ V+  +L ++  +     ++G ++ ++N +    +   E + +L  +  L + ++  G        N  + Y W+D     +  PP      + T+  + S+             K + L+ D  + +G+ I GG +Y LGIYI+ +   S     G + GD+IL++N  SF   + P   EA   L       + V    +LP    +       VG ++                     D  +    K  F+KG   +Q+T +SL   S   LE Q     ++ +   + + +++Y +  + V QLV A+
Sbjct:  179 RHKSQEGLGFSIRG----GSEHGVGIYVSLVEPGSLAEKEGL-----RVGDQILKVNDKVFDAVTHAEAVKVLKGNKKLSMSVRSVGRIPGGYVTN--HVYTWVDPQGRSVSPPPDLMEHRSATLRRNESQRRSNMQLLQEGDEKKVNLVLDDGRSLGLMIRGGAEYALGIYITGVDRSSAAECGGLKVGDQILEVNGRSFL--SIP-HDEAVRVLKSSRHLMMTVKDVGRLPHARTV-------VGETKWIASSQITDSSSSSSVAGLSLDHGASASGKAGFYKGVAGSQVTLSSLVNQSRAMLEEQARHLLTEPERQTMNYYIQEYRDGHIGVEQLVMAL 499

HSP 3 Score: 52.373 bits (124), Expect = 2.125e-6
Identity = 34/107 (31.78%), Postives = 58/107 (54.21%), Query Frame = 1

Query:  961 IELLKDVSQE-IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP---MTDKIQ---EPRSRSV 1260
            + L +  SQE +G +I GG ++ +GIY+S ++PGS+    G + GD+IL++N   F   +    AEA   L       + V S  ++P   +T+ +    +P+ RSV
Sbjct:  175 VTLKRHKSQEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILKVNDKVF---DAVTHAEAVKVLKGNKKLSMSVRSVGRIPGGYVTNHVYTWVDPQGRSV 278

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000039104.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000027.1:1512563:1531320:-1 gene:ENSAMXG00000036967.1 transcript:ENSAMXT00000039104.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.411 bits (189), Expect = 1.342e-14
Identity = 42/90 (46.67%), Postives = 55/90 (61.11%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNS 2361
            LV V K+   LGI++EGG NT  PL RI  +     A LC ++  G +ILEVNG+ L GMEH   A+ IAE+FK+   D I FL+   N+
Sbjct:  305 LVRVSKSANTLGIAVEGGANTRQPLPRIVTIQKGGSAHLCRQLRVGQVILEVNGVSLKGMEHRDAARLIAEAFKTKEKDYIDFLITDFNT 394

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000039257.1 (pep primary_assembly:Astyanax_mexicanus-2.0:6:17529117:17547512:1 gene:ENSAMXG00000040221.1 transcript:ENSAMXT00000039257.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.5438 bits (153), Expect = 7.288e-10
Identity = 40/140 (28.57%), Postives = 68/140 (48.57%), Query Frame = 1

Query:  718 IGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHPPLNYTICLDHSR---LKPIELLKDVSQE-IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSF 1125
            +G +L ++NG     +  +  + +L     L L+LQ  G      + +      W+D ++ R+       ++   HS     + + L   +SQ  +G+NI GG +Y LGIY+S + PG +    G + GD+IL  N VSF
Sbjct:  126 VGDKLLEVNGISLENISMDSAVKVLMGHRRLRLVLQRVGWVPGVRYSS--EKTTWVDLIHRRMVVDEGEASLSGSHSDGALCRSVHLQTSLSQPYLGLNIRGGTEYGLGIYVSKLDPGGLAEQGGIKMGDQILSANGVSF 263

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: ush1c (Usher syndrome 1C [Source:ZFIN;Acc:ZDB-GENE-060312-41])

HSP 1 Score: 58.5362 bits (140), Expect = 2.416e-8
Identity = 70/258 (27.13%), Postives = 117/258 (45.35%), Query Frame = 1

Query:  502 PLNFASEY-----FNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGV-----SSEDI--WENVGNDYKWIDCVNDRICHPPLNYTICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTF--KLPMTDK 1233
            PL    EY       SR L   RL R+   H     LS+R  G+E+        ++I+ +  V   +  N+    +Q+G  + +ING   S    EE I+++     + L ++  G+     SSED   W+ V    +++    ++        ++     + K + L    +  +GI+I  G     GIYIS++KPGS+ + +G Q GD+I+++N V FT  +     EA   L    S  I V +    +L MTD+
Sbjct:   67 PLKHQVEYDQLTPKRSRKLKEVRLDRM---HPEGLGLSVR-GGLEF-----GCGLFISQI--VKDGQAGNV---GLQVGDEIVRINGYSISSCIHEEVINLIKTKKIVSLKVRHVGMIPVKSSSEDPLKWQFVD---QFVSESGEKKNSIAGMASLGGKEIKEKKVFLSLVGTTGMGISISSGPTQKPGIYISNVKPGSLSAEVGLQVGDQIVEVNGVDFTNVD---HKEAVRVLKSSRSLTITVLTGAGSELFMTDE 304

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Nematostella
Match: EDO44244 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWE0])

HSP 1 Score: 61.6178 bits (148), Expect = 8.239e-10
Identity = 101/485 (20.82%), Postives = 193/485 (39.79%), Query Frame = 1

Query:  121 FTDNENKSISSILNDFKLNRSIQYLVDNIQPYIDTKVKLIFLHCLYEIIPSSHQERYYNYCSSKGLRFNKFGQXXXXXXXXXXXXQRAYNCNSYFDCDQIDGEAFDMFETKSSSSFRNDNILTKRKNPLNFASEYFNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKG-VSSEDIWENVGNDYKWIDCVNDRICHPP----LNYTICLDHSRLKPIELLKDVSQ-----------EIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPM----TDKIQEPRSRSV-GRSRRKDDMYSVLES-----KGMFHKG-QRNQLTHTSLTQPSLGNLEI-QLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAI 1491
             +D E       LN ++ NR +  LV +++  +++  K      L EIIPS  ++R+Y         F+K  Q +       +   R                  DM    +S         T RK P+         R L I R      Q+C  +   +R        S     +Y++++D  ++ +   +       G  +  +N  +   +  ++ + I+ +S  L ++++  G + +  + E     Y+WID   ++I  PP       ++  D      + LL D  +           ++G+ I GG +Y LGIYI+ +   S  S  G + GD+I+ +N  SF        A A  AL    +  + +    +LP+    TDK +  + ++  G+  + +  +  ++S     K  F  G    QL +   T PS  NL   Q  +  ++ ++  + + + +Y+   ++V   V A+
Sbjct:   26 LSDQERAYFIQSLNRYQRNRDVDSLVASLKTVLNSPKKRQVFPILREIIPS--RDRHY---------FDKTWQGNRAQLRPVAKVSR-----------------IDMPNGTTSR--------TSRKYPI---------RKLQIKR-----PQNCG-FGFCMR------GGSEHGVGLYVSSIDTGSVSEAIGLLP-----GDHILAVNDVNFDGLTHDQAVKIIRSSKKLSVVVRSVGRIPNTFVAEAT---YRWIDPRGNQIPAPPNVDSSGRSLSADGIHKSDLRLLGDDDERKVNVFVEDGGKLGLKIRGGAEYGLGIYIAGVDEHSAASRAGLKCGDQIMDVNGTSFL---NISHASAIKALKANKNMMVTIKDVGRLPLAKTTTDKTRWSKGQTPNGKVAKTNSGHWGMQSVERPEKSKFQHGIAGTQLIYHG-TGPSTKNLTTEQAKQVLNENELGTMTYYIREYTKGWISVDAFVLAL 441

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Nematostella
Match: EDO48682 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIC6])

HSP 1 Score: 52.373 bits (124), Expect = 2.060e-8
Identity = 26/65 (40.00%), Postives = 40/65 (61.54%), Query Frame = 1

Query:  937 LDHSRLKPIELLKDVSQE--IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSF 1125
            L+ S  + + L+ + +Q   IG N+ GG +Y LGIY+S +  GS+    GF+ GD+IL +N  SF
Sbjct:    3 LNRSEERRVNLVVEPTQTGFIGFNLRGGAEYGLGIYVSGVDQGSLAEQAGFRVGDQILNVNDKSF 67

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Nematostella
Match: EDO27952 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DUS2])

HSP 1 Score: 55.4546 bits (132), Expect = 7.700e-8
Identity = 32/92 (34.78%), Postives = 50/92 (54.35%), Query Frame = 1

Query:  958 PIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIG-FQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTD 1230
            PIE+ K ++   G+N+ GG D L GI++ S+ PG      G  + GD+I +INSVS  G N   + +A   L +  +T   +   F+ P +D
Sbjct:  739 PIEIPK-LNGSFGLNVTGGHD-LGGIFVKSLLPGGAAEASGKIKVGDRITEINSVSMEGLN---RKQAVELLRRSAATATLMIERFRQPQSD 825

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: whrna (whirlin [Source:NCBI gene;Acc:101168386])

HSP 1 Score: 82.8037 bits (203), Expect = 8.340e-16
Identity = 43/89 (48.31%), Postives = 54/89 (60.67%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            LV VPK+   LGI+IEGG NT  PL RI  +     A  CG++  G IILEVNG+ L G EH   A+ IAE+FK+   D + FL+   N
Sbjct:  761 LVRVPKSASTLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGQIILEVNGVSLRGREHRDAARLIAEAFKNKERDYVDFLVTDFN 849

HSP 2 Score: 73.559 bits (179), Expect = 5.473e-13
Identity = 91/382 (23.82%), Postives = 163/382 (42.67%), Query Frame = 1

Query:  574 QHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHPP---------LNYTICLDHSRL--------KPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMT--DKIQEPRSRSVGRSRRKDDMYSVLESKG-----MFHKG-QRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNTLRVNDRMTFK---MKLEVIQALREEKASITTS 1635
            +H ++  L   I G     S     IY++ V+  +L ++  +     +IG ++ ++N +   K+   E + +L  S  L L ++  G        N  + Y W+D     +  PP         L  T     S +        K + L+ D  + +G+ I GG +Y LGIYI+ +  GS     G + GD+IL++N  SF            S  H+ D+  + + S+  L MT  D  + P +R+V    +      + ES        F+KG   +Q+T +SL   S   LE Q     ++ +   + + +E+Y +  + V QLV A+   ++      L++ +   +   D   F    ++ E IQAL+  + +   S
Sbjct:  125 RHKSQEGLGFSIRG----GSEHGVGIYVSLVEPGSLAEKQGL-----RIGDQIMKVNDKVFDKVTHAEAVKVLKGSKKLSLSVRSVGRIPGGYVTN--HVYTWVDPQGRSVSPPPDLPEHRSATLRRTDSQRRSNMQLLQEGDEKKVNLVLDDGRSLGLMIRGGAEYALGIYITGVDKGSAAECGGLKVGDQILEVNGHSF-----------LSIPHE-DAVKV-LKSSRHLMMTVKDVGRLPHARTVVGETKWIASSQIAESSANSSMPGFYKGVAGSQVTLSSLVNQSRAMLEEQARHLLTEAERQTMNYYVEEYRDGHVGVEQLVMALFELLNTHAKFSLLSEVRGLVTPQDLERFDGLVLRRE-IQALKARQGAAGAS 481

HSP 3 Score: 51.9878 bits (123), Expect = 2.585e-6
Identity = 33/110 (30.00%), Postives = 60/110 (54.55%), Query Frame = 1

Query:  952 LKPIELLKDVSQE-IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP---MTDKIQ---EPRSRSV 1260
            L+ + + +  SQE +G +I GG ++ +GIY+S ++PGS+    G + GD+I+++N   F   +    AEA   L       + V S  ++P   +T+ +    +P+ RSV
Sbjct:  118 LRQVTMKRHKSQEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKQGLRIGDQIMKVNDKVF---DKVTHAEAVKVLKGSKKLSLSVRSVGRIPGGYVTNHVYTWVDPQGRSV 224

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: whrna (whirlin [Source:NCBI gene;Acc:101168386])

HSP 1 Score: 81.6481 bits (200), Expect = 2.012e-15
Identity = 43/89 (48.31%), Postives = 54/89 (60.67%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSN 2358
            LV VPK+   LGI+IEGG NT  PL RI  +     A  CG++  G IILEVNG+ L G EH   A+ IAE+FK+   D + FL+   N
Sbjct:  875 LVRVPKSASTLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGQIILEVNGVSLRGREHRDAARLIAEAFKNKERDYVDFLVTDFN 963

HSP 2 Score: 75.0998 bits (183), Expect = 1.968e-13
Identity = 88/387 (22.74%), Postives = 161/387 (41.60%), Query Frame = 1

Query:  574 QHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKG-VSSEDIWENVGNDYKWIDCVNDRICHPP---------LNYTICLDHSRL--------KPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP------------MTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNTLRVNDRMTFK---MKLEVIQALREEKASITTS 1635
            +H ++  L   I G     S     IY++ V+  +L ++  +     +IG ++ ++N +   K+   E + +L  S  L L ++  G +    +  +V   Y W+D     +  PP         L  T     S +        K + L+ D  + +G+ I GG +Y LGIYI+ +  GS     G + GD+IL++N  SF   + P + +A   L       + V    +LP             + +I E  + S   S   +   SV    G +     +Q+T +SL   S   LE Q     ++ +   + + +E+Y +  + V QLV A+   ++      L++ +   +   D   F    ++ E IQAL+  + +   S
Sbjct:  187 RHKSQEGLGFSIRG----GSEHGVGIYVSLVEPGSLAEKQGL-----RIGDQIMKVNDKVFDKVTHAEAVKVLKGSKKLSLSVRSVGRIPGGYVTNHV---YTWVDPQGRSVSPPPDLPEHRSATLRRTDSQRRSNMQLLQEGDEKKVNLVLDDGRSLGLMIRGGAEYALGIYITGVDKGSAAECGGLKVGDQILEVNGHSFL--SIPHE-DAVKVLKSSRHLMMTVKDVGRLPHARTVVGETKWIASSQIAESSANSSMASFSVEQGASVAGKPGFYKGVAGSQVTLSSLVNQSRAMLEEQARHLLTEAERQTMNYYVEEYRDGHVGVEQLVMALFELLNTHAKFSLLSEVRGLVTPQDLERFDGLVLRRE-IQALKARQGAAGAS 557

HSP 3 Score: 51.2174 bits (121), Expect = 4.820e-6
Identity = 33/110 (30.00%), Postives = 60/110 (54.55%), Query Frame = 1

Query:  952 LKPIELLKDVSQE-IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLP---MTDKIQ---EPRSRSV 1260
            L+ + + +  SQE +G +I GG ++ +GIY+S ++PGS+    G + GD+I+++N   F   +    AEA   L       + V S  ++P   +T+ +    +P+ RSV
Sbjct:  180 LRQVTMKRHKSQEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKQGLRIGDQIMKVNDKVF---DKVTHAEAVKVLKGSKKLSLSVRSVGRIPGGYVTNHVYTWVDPQGRSV 286

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: whrnb (whirlin [Source:NCBI gene;Acc:101156094])

HSP 1 Score: 77.411 bits (189), Expect = 3.346e-14
Identity = 42/90 (46.67%), Postives = 54/90 (60.00%), Query Frame = 1

Query: 2092 LVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNS 2361
            LV V K    LGI+IEGG NT  PL RI  +     A  CG++  G +ILEVNG+ + G EH   A+ IAE+FK+   D I FL++ S S
Sbjct:  681 LVRVLKNADTLGIAIEGGANTRQPLPRIVTLQKGGSAYNCGQLKVGHVILEVNGVSMRGREHKDAARIIAEAFKTKEKDHIDFLVVDSGS 770

HSP 2 Score: 51.9878 bits (123), Expect = 2.569e-6
Identity = 42/169 (24.85%), Postives = 74/169 (43.79%), Query Frame = 1

Query:  631 SHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKG-VSSEDIWENVGNDYKWIDCVNDRICHPPLNYTICLDHSRLKP---IELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSF 1125
            S     IY++ V+  +  +R  +     +IG ++   N      +   E + +L     L + +   G +    I  +V   Y W+D     +  PP +     D  +  P   + L  +    +G+ I GG +Y LGIYI+ + PGS   +   + GD+IL++N  SF
Sbjct:  143 SEHGVGIYVSLVEPGSSAQREGL-----RIGDQIVAANDMMFDNVTHVEAVKVLKGCRTLTMSVCSMGRIPGNHITNHV---YSWVDPQGRGVSPPPDSQ----DADQRGPERMVSLNMEDGLSLGLMIRGGAEYGLGIYITGVDPGSAADVGALKVGDQILEVNDQSF 299

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: pdzd7a (membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 [Source:NCBI gene;Acc:101157152])

HSP 1 Score: 59.6918 bits (143), Expect = 1.299e-8
Identity = 44/173 (25.43%), Postives = 78/173 (45.09%), Query Frame = 1

Query:  631 SHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRIC------HPPLNYTICLDHSRLKPIELLKDVSQE--IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSF 1125
            S     I+++ VDD      ++  +  + +G +L ++NG     +     + +L  +  L ++L+  G      +        W+D ++ R+        P    + C     L+ I  L   S +  +G NI GGK++ LGIY+S + PG +    G + GD+IL  N VSF
Sbjct:   93 SEHGLGIFVSKVDD-----DSSAAQAGLTVGDKLVEVNGVSLESITMSSAVKVLTGNNRLRMVLRRVGKIPGIRYSK--EKTTWVDLIHRRMVVEEGSGAPSEASSDCA----LRRIVHLFTTSDDYCLGFNIRGGKEFGLGIYVSKLDPGGLAEQHGIKMGDQILAANGVSF 254

HSP 2 Score: 55.0694 bits (131), Expect = 2.935e-7
Identity = 31/85 (36.47%), Postives = 46/85 (54.12%), Query Frame = 1

Query: 2095 VTVPKAVPMLGISIEGGINTP-HPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLL 2346
            VT+ KA P LGISI GGI +   P+ +I K+ P   A     +  GD +L V+G  L G+ H      I  +F + + DP+ F++
Sbjct:  874 VTISKAKPSLGISISGGIESKIQPMIKIEKIFPGGAASTNEALKAGDELLSVDGKSLQGVTHLHAVDLIRRAFSNKAKDPMVFVV 958

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: pdzd7a (membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 [Source:NCBI gene;Acc:101157152])

HSP 1 Score: 59.3066 bits (142), Expect = 1.703e-8
Identity = 44/173 (25.43%), Postives = 78/173 (45.09%), Query Frame = 1

Query:  631 SHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRIC------HPPLNYTICLDHSRLKPIELLKDVSQE--IGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSF 1125
            S     I+++ VDD      ++  +  + +G +L ++NG     +     + +L  +  L ++L+  G      +        W+D ++ R+        P    + C     L+ I  L   S +  +G NI GGK++ LGIY+S + PG +    G + GD+IL  N VSF
Sbjct:   93 SEHGLGIFVSKVDD-----DSSAAQAGLTVGDKLVEVNGVSLESITMSSAVKVLTGNNRLRMVLRRVGKIPGIRYSK--EKTTWVDLIHRRMVVEEGSGAPSEASSDCA----LRRIVHLFTTSDDYCLGFNIRGGKEFGLGIYVSKLDPGGLAEQHGIKMGDQILAANGVSF 254

HSP 2 Score: 55.0694 bits (131), Expect = 2.857e-7
Identity = 31/85 (36.47%), Postives = 46/85 (54.12%), Query Frame = 1

Query: 2095 VTVPKAVPMLGISIEGGINTP-HPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLL 2346
            VT+ KA P LGISI GGI +   P+ +I K+ P   A     +  GD +L V+G  L G+ H      I  +F + + DP+ F++
Sbjct:  869 VTISKAKPSLGISISGGIESKIQPMIKIEKIFPGGAASTNEALKAGDELLSVDGKSLQGVTHLHAVDLIRRAFSNKAKDPMVFVV 953

[Close]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Match: SMESG000023278.1 (SMESG000023278.1)

HSP 1 Score: 1592.79 bits (4123), Expect = 0.000e+0
Identity = 784/787 (99.62%), Postives = 786/787 (99.87%), Query Frame = 1

Query:   49 MNRLKNKNEVSTKVYNIKTAMKSLFTDNENKSISSILNDFKLNRSIQYLVDNIQPYIDTKVKLIFLHCLYEIIPSSHQERYYNYCSSKGLRFNKFGQXXXXXXXXXXXXQRAYNCNSYFDCDQIDGEAFDMFETKSSSSFRNDNILTKRKNPLNFASEYFNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHPPLNYTICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNTLRVNDRMTFKMKLEVIQALREEKASITTSRSAHQTPIFQRPNLTENVGENDEISVIRRPIFKKPEFSHQNSSNSEKDLPFKEQTMESLDCEFQEKPSLFDEIRKINKDNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISRKTISTPKEYISMQYNIPKEEIIKLAGNKLKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNSEKIDESDCIDYQSTYL 2409
            MNRLKNKNEVSTKVYNIKTAMKSLFTDNENKSISSILNDFKLNRSIQYLVDNIQPYIDTKVKLIFLHCLYEIIPSSHQERYYNYCSSKGLRFNKFGQNSFDFNNSPSFNQRAYNCNSYFDCDQIDGEAFDMFETKSSSSFRNDNILTKRKNPLNFASEYFNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKD+EFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHPPLNYTICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDS DIWVYSTFKLPMTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNTLRVNDRMTFKMKLEVIQALREEKASITTSRSAHQTPIFQRPNLTENVGENDEISVIRRPIFKKPEFSHQNSSNSEKDLPFKEQTMESLDCEFQEKPSLFDEIRKINKDNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISRKTISTPKEYISMQYNIPKEEIIKLAGNKLKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSC+GLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNSEKIDESDCIDYQSTYL
Sbjct:    1 MNRLKNKNEVSTKVYNIKTAMKSLFTDNENKSISSILNDFKLNRSIQYLVDNIQPYIDTKVKLIFLHCLYEIIPSSHQERYYNYCSSKGLRFNKFGQNSFDFNNSPSFNQRAYNCNSYFDCDQIDGEAFDMFETKSSSSFRNDNILTKRKNPLNFASEYFNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYSIYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDDEFIDILNNSMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHPPLNYTICLDHSRLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDKILQINSVSFTGSNTPCQAEAFSALHQCDSADIWVYSTFKLPMTDKIQEPRSRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSEFTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNTLRVNDRMTFKMKLEVIQALREEKASITTSRSAHQTPIFQRPNLTENVGENDEISVIRRPIFKKPEFSHQNSSNSEKDLPFKEQTMESLDCEFQEKPSLFDEIRKINKDNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISRKTISTPKEYISMQYNIPKEEIIKLAGNKLKKLVTVPKAVPMLGISIEGGINTPHPLARITKVDPDSCSGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKIAESFKSLSTDPITFLLMKSNSEKIDESDCIDYQSTYL 787

The following BLAST results are available for this feature:

BLAST of PDZ domain-containing protein vs. Ensembl Human
BLAST of PDZ domain-containing protein vs. Ensembl Celegans
BLAST of PDZ domain-containing protein vs. Ensembl Fly
BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
BLAST of PDZ domain-containing protein vs. Ensembl Mouse
BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
BLAST of PDZ domain-containing protein vs. TrEMBL
BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
BLAST of PDZ domain-containing protein vs. Ensembl Sea Lamprey
BLAST of PDZ domain-containing protein vs. Ensembl Yeast
BLAST of PDZ domain-containing protein vs. Ensembl Nematostella
BLAST of PDZ domain-containing protein vs. Ensembl Medaka
BLAST of PDZ domain-containing protein vs. Planmine SMEST

BLAST of PDZ domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
WHRN	9.996e-15	33.33	whirlin [Source:HGNC Symbol;Acc:HGNC:16361]	[more]
WHRN	1.005e-14	33.33	whirlin [Source:HGNC Symbol;Acc:HGNC:16361]	[more]
WHRN	1.664e-14	32.40	whirlin [Source:HGNC Symbol;Acc:HGNC:16361]	[more]
WHRN	2.481e-14	33.15	whirlin [Source:HGNC Symbol;Acc:HGNC:16361]	[more]
USH1C	3.742e-7	25.83	USH1 protein network component harmonin [Source:HG...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dysc	4.304e-13	39.78	gene:FBgn0264006 transcript:FBtr0330418	[more]
dysc	4.633e-13	39.78	gene:FBgn0264006 transcript:FBtr0330414	[more]
dysc	4.723e-13	39.78	gene:FBgn0264006 transcript:FBtr0330419	[more]
dysc	4.812e-13	39.78	gene:FBgn0264006 transcript:FBtr0330417	[more]
dysc	5.571e-13	39.78	gene:FBgn0264006 transcript:FBtr0333021	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
whrnb	8.345e-18	34.64	whirlin b [Source:ZFIN;Acc:ZDB-GENE-060526-377]	[more]
whrna	3.798e-15	45.65	whirlin a [Source:ZFIN;Acc:ZDB-GENE-091118-27]	[more]
whrna	3.963e-15	45.65	whirlin a [Source:ZFIN;Acc:ZDB-GENE-091118-27]	[more]
whrnb	3.750e-8	21.63	whirlin b [Source:ZFIN;Acc:ZDB-GENE-060526-377]	[more]
pdzd7a	2.683e-7	25.00	PDZ domain containing 7a [Source:ZFIN;Acc:ZDB-GENE...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
WHRN	1.415e-13	44.94	whirlin [Source:NCBI gene;Acc:100486736]	[more]
ENSXETT00000028683.1	3.617e-6	30.95	lin-7 homolog B [Source:NCBI gene;Acc:100491827]	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Whrn	8.619e-14	47.19	whirlin [Source:MGI Symbol;Acc:MGI:2682003]	[more]
Whrn	9.420e-14	47.19	whirlin [Source:MGI Symbol;Acc:MGI:2682003]	[more]
Whrn	1.210e-13	47.19	whirlin [Source:MGI Symbol;Acc:MGI:2682003]	[more]
Whrn	1.324e-13	47.19	whirlin [Source:MGI Symbol;Acc:MGI:2682003]	[more]
Whrn	1.354e-13	47.19	whirlin [Source:MGI Symbol;Acc:MGI:2682003]	[more]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9P202\|WHRN_HUMAN	7.992e-14	32.40	Whirlin OS=Homo sapiens OX=9606 GN=WHRN PE=1 SV=4	[more]
sp\|Q80VW5\|WHRN_MOUSE	8.462e-13	47.19	Whirlin OS=Mus musculus OX=10090 GN=Whrn PE=1 SV=3	[more]
sp\|Q810W9\|WHRN_RAT	1.086e-12	46.07	Whirlin OS=Rattus norvegicus OX=10116 GN=Whrn PE=1...	[more]
sp\|Q9ES64\|USH1C_MOUSE	1.259e-6	26.20	Harmonin OS=Mus musculus OX=10090 GN=Ush1c PE=1 SV...	[more]
sp\|Q9Z252\|LIN7B_RAT	2.727e-6	31.06	Protein lin-7 homolog B OS=Rattus norvegicus OX=10...	[more]

BLAST of PDZ domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5E4NAN0	3.371e-22	22.13	Uncharacterized protein OS=Cinara cedri OX=506608 ...	[more]
A0A5E4NGN3	1.406e-20	21.77	Uncharacterized protein OS=Cinara cedri OX=506608 ...	[more]
A0A5E4ND79	1.495e-20	21.57	PDZ domain OS=Cinara cedri OX=506608 GN=CINCED_3A0...	[more]
A0A5E4NAA2	3.541e-20	21.52	Uncharacterized protein OS=Cinara cedri OX=506608 ...	[more]
C3ZWT6	1.270e-15	47.06	PDZ domain-containing protein (Fragment) OS=Branch...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
whrna	2.665e-16	48.31	whirlin [Source:NCBI gene;Acc:103029719]	[more]
whrna	3.687e-16	48.31	whirlin [Source:NCBI gene;Acc:103029719]	[more]
ENSAMXT00000039104.1	1.342e-14	46.67	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000039257.1	7.288e-10	28.57	pep primary_assembly:Astyanax_mexicanus-2.0:6:1752...	[more]
ush1c	2.416e-8	27.13	Usher syndrome 1C [Source:ZFIN;Acc:ZDB-GENE-060312...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PDZ domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PDZ domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3


Match Name	E-value	Identity	Description
EDO44244	8.239e-10	20.82	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48682	2.060e-8	40.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27952	7.700e-8	34.78	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
whrna	8.340e-16	48.31	whirlin [Source:NCBI gene;Acc:101168386]	[more]
whrna	2.012e-15	48.31	whirlin [Source:NCBI gene;Acc:101168386]	[more]
whrnb	3.346e-14	46.67	whirlin [Source:NCBI gene;Acc:101156094]	[more]
pdzd7a	1.299e-8	25.43	membrane-associated guanylate kinase, WW and PDZ d...	[more]
pdzd7a	1.703e-8	25.43	membrane-associated guanylate kinase, WW and PDZ d...	[more]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000023278.1	0.000e+0	99.62	SMESG000023278.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30006669 ID=SMED30006669|Name=PDZ domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2472bp
AATAATAATTTTTATACCAAAACCTTTTGAATTCTCAACAAAACCTCAAT
GAATCGATTGAAAAATAAAAACGAAGTTTCAACCAAAGTTTACAACATTA
AAACTGCTATGAAATCATTATTCACAGACAATGAAAATAAATCTATTTCA
TCCATATTAAATGATTTCAAATTGAACCGAAGCATTCAATATCTTGTTGA
CAACATTCAGCCATACATCGACACAAAAGTCAAATTAATTTTCCTTCATT
GCCTCTACGAAATAATTCCTAGCAGCCACCAGGAACGATATTACAATTAC
TGCTCATCGAAAGGTTTACGTTTCAACAAATTTGGACAGAACTCTTTTGA
TTTCAATAATTCACCTTCCTTCAATCAACGAGCTTATAACTGTAATTCAT
ATTTTGATTGCGATCAAATTGATGGAGAAGCATTTGACATGTTCGAAACG
AAATCCTCCAGCTCCTTTCGAAATGACAACATTCTAACCAAGCGAAAGAA
TCCTCTCAATTTTGCTTCAGAATATTTCAATAGTCGGCATTTGTTTATTT
GCAGACTAACAAGACTTTCTAGTCAGCATTGCAATAAATATGAATTATCT
CTTCGGATTTGGGGAATCGAATGGTGGAGAAGCCATTCAACATATTCAAT
ATACATTACCAATGTTGATGATGTAACTTTGTATAAGAGAAACAACATTT
ACGAACGCGATATCCAAATTGGTCAGAGACTGAAACAAATCAACGGAAGA
GATGCATCAAAAATGAAGGATGAAGAGTTTATAGATATTCTCAATAATTC
AATGTTCCTAGATTTGATTCTTCAGGGGAAAGGGGTTTCTAGTGAAGACA
TATGGGAAAATGTCGGCAATGACTATAAATGGATTGATTGTGTCAATGAT
AGAATTTGTCACCCCCCGTTGAATTATACTATATGTTTAGACCATTCCCG
CCTGAAACCAATTGAGCTACTAAAGGATGTCTCACAAGAAATTGGTATCA
ATATATGTGGAGGAAAAGATTACTTATTGGGCATTTATATCAGTTCTATC
AAACCTGGTTCCATAGGATCAATGATCGGGTTCCAGACCGGTGACAAAAT
TCTGCAAATAAATTCCGTCAGTTTTACTGGGTCGAATACTCCTTGCCAGG
CTGAGGCATTCAGTGCTCTTCATCAATGTGACAGCACCGATATTTGGGTT
TATTCTACGTTTAAACTGCCAATGACAGACAAAATCCAAGAACCCAGAAG
CCGATCAGTTGGACGTTCAAGAAGAAAAGATGACATGTATTCAGTGCTTG
AATCAAAGGGGATGTTTCATAAAGGCCAAAGAAATCAGCTAACTCATACC
AGCCTCACTCAACCATCTTTGGGAAATCTAGAAATACAACTGTCCGAATT
CACCAGCAAACAAGACGTGAACAAAATATTATTTCTGTTGGAAAAATATT
CAAATACAGAGCTGAATGTCCACCAACTGGTAACAGCAATACAGCACCAT
ATCCATGGGATTTGGACCATGAAGCTTATCAACCTAATTTCAAATACCCT
TCGAGTTAATGATCGGATGACCTTCAAAATGAAATTGGAAGTCATTCAAG
CGTTGCGCGAAGAAAAGGCATCAATAACAACATCAAGAAGTGCACATCAA
ACGCCAATTTTCCAACGTCCAAATTTAACGGAAAATGTAGGAGAAAATGA
TGAGATTTCTGTCATAAGAAGACCAATATTCAAAAAGCCTGAGTTCAGTC
ATCAAAATTCCTCAAACTCAGAAAAAGATTTACCATTCAAAGAACAAACT
ATGGAATCTTTAGATTGTGAGTTCCAAGAAAAGCCATCATTATTTGATGA
GATCCGAAAAATAAACAAAGATAATAAAAAAGAAATTCTGGAAGAAACTG
AAAATACAATCAAAGAAAAGCGTCAAACAATGAAAGAGAGTCAAAATTTA
GAAAAAAATGTTGACATAGAAGATGAAGAAATCAAGGTGATTTCTCGAAA
GACAATATCGACACCAAAAGAGTACATTTCAATGCAATATAATATTCCAA
AAGAAGAAATTATAAAATTAGCAGGAAATAAATTGAAAAAGTTAGTAACT
GTTCCAAAAGCAGTTCCGATGTTAGGGATTTCAATAGAAGGAGGCATCAA
TACCCCCCATCCTTTAGCAAGGATCACAAAAGTCGATCCCGATAGTTGCG
CAGGCCTATGCGGTGAAATGTCTAGAGGCGATATTATTCTCGAAGTCAAT
GGGATACCTTTGACTGGTATGGAACACAACAAAATTGCCCAAAAAATTGC
CGAATCGTTCAAATCATTATCTACTGACCCGATCACATTTTTGCTGATGA
AATCTAACAGTGAAAAAATCGATGAATCCGACTGTATTGATTATCAGAGC
ACTTATCTCTAAAACTGGATTTCTAGAGAAAATTATAATTTCACTGCACG
AATAGCATTTGTAATAAATAAT

protein sequence of SMED30006669-orf-1

>SMED30006669-orf-1 ID=SMED30006669-orf-1|Name=SMED30006669-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=788bp
MNRLKNKNEVSTKVYNIKTAMKSLFTDNENKSISSILNDFKLNRSIQYLV
DNIQPYIDTKVKLIFLHCLYEIIPSSHQERYYNYCSSKGLRFNKFGQNSF
DFNNSPSFNQRAYNCNSYFDCDQIDGEAFDMFETKSSSSFRNDNILTKRK
NPLNFASEYFNSRHLFICRLTRLSSQHCNKYELSLRIWGIEWWRSHSTYS
IYITNVDDVTLYKRNNIYERDIQIGQRLKQINGRDASKMKDEEFIDILNN
SMFLDLILQGKGVSSEDIWENVGNDYKWIDCVNDRICHPPLNYTICLDHS
RLKPIELLKDVSQEIGINICGGKDYLLGIYISSIKPGSIGSMIGFQTGDK
ILQINSVSFTGSNTPCQAEAFSALHQCDSTDIWVYSTFKLPMTDKIQEPR
SRSVGRSRRKDDMYSVLESKGMFHKGQRNQLTHTSLTQPSLGNLEIQLSE
FTSKQDVNKILFLLEKYSNTELNVHQLVTAIQHHIHGIWTMKLINLISNT
LRVNDRMTFKMKLEVIQALREEKASITTSRSAHQTPIFQRPNLTENVGEN
DEISVIRRPIFKKPEFSHQNSSNSEKDLPFKEQTMESLDCEFQEKPSLFD
EIRKINKDNKKEILEETENTIKEKRQTMKESQNLEKNVDIEDEEIKVISR
KTISTPKEYISMQYNIPKEEIIKLAGNKLKKLVTVPKAVPMLGISIEGGI
NTPHPLARITKVDPDSCAGLCGEMSRGDIILEVNGIPLTGMEHNKIAQKI
AESFKSLSTDPITFLLMKSNSEKIDESDCIDYQSTYL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR036034	PDZ_sf
IPR033028	Whirlin
IPR001478	PDZ

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

Vocabulary: **biological process**
Term	Definition
GO:0007605	sensory perception of sound
GO:0050953	sensory perception of light stimulus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 607..651
None	No IPR available	PANTHER	PTHR23116	PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED	coord: 14..88 coord: 312..361
None	No IPR available	PANTHER	PTHR23116	PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED	coord: 562..771
None	No IPR available	CDD	cd00992	PDZ_signaling	coord: 302..377 e-value: 2.63425E-14 score: 66.8214
None	No IPR available	CDD	cd00992	PDZ_signaling	coord: 681..757 e-value: 3.74293E-11 score: 57.5767
IPR001478	PDZ domain	SMART	SM00228	pdz_new	coord: 313..388 e-value: 1.9E-4 score: 30.8 coord: 179..262 e-value: 7.0 score: 4.6 coord: 690..770 e-value: 8.0E-8 score: 42.0
IPR001478	PDZ domain	PFAM	PF00595	PDZ	coord: 309..361 e-value: 3.1E-6 score: 27.4 coord: 691..753 e-value: 7.3E-7 score: 29.5
IPR001478	PDZ domain	PROSITE	PS50106	PDZ	coord: 682..753 score: 12.546
IPR001478	PDZ domain	PROSITE	PS50106	PDZ	coord: 304..361 score: 12.968
IPR036034	PDZ superfamily	GENE3D	G3DSA:2.30.42.10		coord: 293..402 e-value: 3.2E-13 score: 51.5
IPR036034	PDZ superfamily	GENE3D	G3DSA:2.30.42.10		coord: 676..775 e-value: 8.3E-17 score: 63.0
IPR036034	PDZ superfamily	SUPERFAMILY	SSF50156	PDZ domain-like	coord: 681..769
IPR036034	PDZ superfamily	SUPERFAMILY	SSF50156	PDZ domain-like	coord: 290..387
IPR033028	Whirlin	PANTHER	PTHR23116:SF37	WHIRLIN	coord: 312..361
IPR033028	Whirlin	PANTHER	PTHR23116:SF37	WHIRLIN	coord: 562..771 coord: 14..88

Main menu

PDZ domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Owlery

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